Periostin

Overview
NamePeriostin
Smed IDSMED30034597
Length (bp)2315
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Periostin (SMED30034597) t-SNE clustered cells

Violin plots show distribution of expression levels for Periostin (SMED30034597) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Periostin (SMED30034597) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Periostin (SMED30034597) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30034597

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30034597h1SMcG0011728 Contig1042GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30034597h1SMcG0011728 dd_Smed_v4_1505_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30034597h1SMcG0011728 dd_Smed_v4_1505_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30034597h1SMcG0011728 Contig39779uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30034597h1SMcG0011728 Contig39779newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
intestinal phagocyteSMED30034597h1SMcG0011728 dd_Smed_v6_1505_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30034597h1SMcG0009514 Contig2530GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30034597h1SMcG0011728 Contig2530GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
gutSMED30034597h1SMcG0011728 dd_Smed_v4_1505_0_1dd_Smed_v4PMID:30962434
Cote et al., 2019
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Periostin vs. Ensembl Human
Match: TGFBI (transforming growth factor beta induced [Source:HGNC Symbol;Acc:HGNC:11771])

HSP 1 Score: 111.694 bits (278), Expect = 1.128e-24
Identity = 138/589 (23.43%), Postives = 243/589 (41.26%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSE---VESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDL----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKI-------SLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDL--KINSFSKYILLIPTN----------EAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWG-----SSELNRLFQLH 1926
            N+CA  K       Y F  C   +++  C   T   Y+CCPG+ K P  +  C     + ++++ + V +   +   +    EK        E  G  ++T+ AP ++    L    L    SNV     + +  H+   R+ +++  +G T  ++  +  +++  Y NG+V ++C  L+  DH A NGV+H I   I+  + +  Q+   ++    D           S L  ML  E +GQ+ T+ AP+N A+E   S+  ++I         L+ NHIL   +CA+AI    +    +L    L V CS D     +     KA I  +D+++ NGV+  ID +L+P SA +  +         ++SDVS+ +   R   L   ++   +  LL P N          +AHT                        +LR H++K +  +    +  + ++    GGK L V  Y       S    N+      +  ++  G +F +DR+  PP  T+M +L       +    +Q  G    +   G   +F A  N  ++    +E       + EL  + + H
Sbjct:   47 NVCAVQKVIGTNRKY-FTNCKQWYQRKICGKSTVISYECCPGYEKVP-GEKGCPAALPLSNLYETLGV-VGSTTTQLYTDRTEKLRP-----EMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVIST-ITNNIQQIIEIE----DTFETLRAAVAASGLNTML--EGNGQY-TLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSV--ETLEGTTLEVGCSGD-----MLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELA-------AESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTPPIDAHTR----------------------NLLRNHIIKDQLASKYLYHGQTLET---LGGKKLRVFVY-----RNSLCIENSCIAAHDKRGRY--GTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVF-APTNEAFRALPPRERSRLLGDAKELANILKYH 572          

HSP 2 Score: 56.6102 bits (135), Expect = 1.773e-7
Identity = 59/223 (26.46%), Postives = 100/223 (44.84%), Query Frame = 1
Query:  637 HIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSE-LREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSK-------ISLLVKNHILNRMICAQAI-------TKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVP 1260
            HI K+++ S    +G T +TL    KL+V  Y N L  I+   +   D   + G +  +   +TP +G      TV+  ++ D   +     IQS  L E L++E      TVFAP+N A+ A   +  S+       ++ ++K HI + ++ +  I       + +   L  SL N  + V               NK  + + D+++ NGVV +I +VL P
Sbjct:  438 HIIKDQLASKYLYHGQTLETLGGK-KLRVFVYRNSLC-IENSCIAAHDKRGRYGTLFTMDRVLTPPMG------TVMDVLKGDNRFSMLVAAIQSAGLTETLNREG---VYTVFAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSV---------------NKEPVAEPDIMATNGVVHVITNVLQP 634          
BLAST of Periostin vs. Ensembl Human
Match: POSTN (periostin [Source:HGNC Symbol;Acc:HGNC:16953])

HSP 1 Score: 109.383 bits (272), Expect = 6.368e-24
Identity = 120/468 (25.64%), Postives = 210/468 (44.87%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYS------DDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F TC   +K++ C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   +++S    L EE  G+ ++T  AP +      D  ++ G     NV    + +  H+   RM +    NG    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    ++A   D L++     I S++ E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C+++I   A     +L    + + C  D     +   G K  + K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + +    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   42 NVCA-LQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMR-------MEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVE-LLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFIEA--EDDLSSFRAAAITSDILEALGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVF--ETLEGNTIEIGCDGDS----ITVNGIKM-VNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASA----LRPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLNELYNGQILET---IGGKQLRVFVY 462          

HSP 2 Score: 53.5286 bits (127), Expect = 1.307e-6
Identity = 60/257 (23.35%), Postives = 114/257 (44.36%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQS-ELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLG--PSLANEYLGVDCSSDKSRSILDAC-GNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAV 1290
            YT+LAP    +SDD + + +  L  +      +  HI K ++  N+  NG   +T+    +L+V  Y    V I+   +     + +NG IH     I P        K++ + ++ D   ++F + +++ +L+E+L Q  D  W T+F P+N A++   S+   K  L+   + L  +I            G  P + N       S    + + D    N+ +  + D+++ NGV+ ++D +L P       D +
Sbjct:  403 YTLLAPVNNAFSDDTLSMDQRLLKLI------LQNHILKVKVGLNELYNGQILETIGG-KQLRVFVYRTA-VCIENSCMEKGSKQGRNGAIHIFREIIKP------AEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGD--W-TLFVPTNDAFKGMTSE--EKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQL 640          
BLAST of Periostin vs. Ensembl Human
Match: POSTN (periostin [Source:HGNC Symbol;Acc:HGNC:16953])

HSP 1 Score: 109.383 bits (272), Expect = 6.451e-24
Identity = 122/468 (26.07%), Postives = 213/468 (45.51%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYSDDAMKLGEFDL-----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F TC   +K++ C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   +++S    L EE  G+ ++T  AP S++A    + D+     SNV     + +  H+   RM +    NG    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    ++A   D L++     I S++ E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C+++I   A     +L    + + C  D     +   G K  + K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + +    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   42 NVCA-LQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMR-------MEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAP-SNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFIEA--EDDLSSFRAAAITSDILEALGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVF--ETLEGNTIEIGCDGDS----ITVNGIKM-VNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASA----LRPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLNELYNGQILET---IGGKQLRVFVY 462          

HSP 2 Score: 53.9138 bits (128), Expect = 1.266e-6
Identity = 60/257 (23.35%), Postives = 114/257 (44.36%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQS-ELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLG--PSLANEYLGVDCSSDKSRSILDAC-GNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAV 1290
            YT+LAP    +SDD + + +  L  +      +  HI K ++  N+  NG   +T+    +L+V  Y    V I+   +     + +NG IH     I P        K++ + ++ D   ++F + +++ +L+E+L Q  D  W T+F P+N A++   S+   K  L+   + L  +I            G  P + N       S    + + D    N+ +  + D+++ NGV+ ++D +L P       D +
Sbjct:  403 YTLLAPVNNAFSDDTLSMDQRLLKLI------LQNHILKVKVGLNELYNGQILETIGG-KQLRVFVYRTA-VCIENSCMEKGSKQGRNGAIHIFREIIKP------AEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGD--W-TLFVPTNDAFKGMTSE--EKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQL 640          
BLAST of Periostin vs. Ensembl Human
Match: POSTN (periostin [Source:HGNC Symbol;Acc:HGNC:16953])

HSP 1 Score: 109.383 bits (272), Expect = 7.404e-24
Identity = 120/468 (25.64%), Postives = 210/468 (44.87%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYS------DDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F TC   +K++ C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   +++S    L EE  G+ ++T  AP +      D  ++ G     NV    + +  H+   RM +    NG    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    ++A   D L++     I S++ E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C+++I   A     +L    + + C  D     +   G K  + K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + +    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   42 NVCA-LQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMR-------MEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVE-LLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFIEA--EDDLSSFRAAAITSDILEALGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVF--ETLEGNTIEIGCDGDS----ITVNGIKM-VNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASA----LRPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLNELYNGQILET---IGGKQLRVFVY 462          

HSP 2 Score: 53.9138 bits (128), Expect = 1.129e-6
Identity = 60/257 (23.35%), Postives = 114/257 (44.36%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQS-ELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLG--PSLANEYLGVDCSSDKSRSILDAC-GNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAV 1290
            YT+LAP    +SDD + + +  L  +      +  HI K ++  N+  NG   +T+    +L+V  Y    V I+   +     + +NG IH     I P        K++ + ++ D   ++F + +++ +L+E+L Q  D  W T+F P+N A++   S+   K  L+   + L  +I            G  P + N       S    + + D    N+ +  + D+++ NGV+ ++D +L P       D +
Sbjct:  403 YTLLAPVNNAFSDDTLSMDQRLLKLI------LQNHILKVKVGLNELYNGQILETIGG-KQLRVFVYRTA-VCIENSCMEKGSKQGRNGAIHIFREIIKP------AEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGD--W-TLFVPTNDAFKGMTSE--EKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQL 640          
BLAST of Periostin vs. Ensembl Human
Match: POSTN (periostin [Source:HGNC Symbol;Acc:HGNC:16953])

HSP 1 Score: 109.383 bits (272), Expect = 7.474e-24
Identity = 120/468 (25.64%), Postives = 210/468 (44.87%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYS------DDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F TC   +K++ C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   +++S    L EE  G+ ++T  AP +      D  ++ G     NV    + +  H+   RM +    NG    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    ++A   D L++     I S++ E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C+++I   A     +L    + + C  D     +   G K  + K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + +    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   42 NVCA-LQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMR-------MEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVE-LLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFIEA--EDDLSSFRAAAITSDILEALGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVF--ETLEGNTIEIGCDGDS----ITVNGIKM-VNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASA----LRPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLNELYNGQILET---IGGKQLRVFVY 462          

HSP 2 Score: 53.9138 bits (128), Expect = 1.286e-6
Identity = 60/257 (23.35%), Postives = 114/257 (44.36%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQS-ELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLG--PSLANEYLGVDCSSDKSRSILDAC-GNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAV 1290
            YT+LAP    +SDD + + +  L  +      +  HI K ++  N+  NG   +T+    +L+V  Y    V I+   +     + +NG IH     I P        K++ + ++ D   ++F + +++ +L+E+L Q  D  W T+F P+N A++   S+   K  L+   + L  +I            G  P + N       S    + + D    N+ +  + D+++ NGV+ ++D +L P       D +
Sbjct:  403 YTLLAPVNNAFSDDTLSMDQRLLKLI------LQNHILKVKVGLNELYNGQILETIGG-KQLRVFVYRTA-VCIENSCMEKGSKQGRNGAIHIFREIIKP------AEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGD--W-TLFVPTNDAFKGMTSE--EKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQL 640          
BLAST of Periostin vs. Ensembl Fly
Match: Fas1 (gene:FBgn0285925 transcript:FBtr0333726)

HSP 1 Score: 50.447 bits (119), Expect = 5.677e-6
Identity = 57/240 (23.75%), Postives = 99/240 (41.25%), Query Frame = 1
Query:  766 LVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNS---FYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKS----KYGSKISLLVKNHILNRMICAQAITKKATSL---GPSLANE---YLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVL-VPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKY 1443
            +V  +    NGV+H I  P+           TV Q +Q +    +   FY  I      +LD  +    +T+ APSN AW ++      +  +K+  ++  HI+   +    I +K  +L    P++ N    Y  V      +   ++  G  A +I+ D+   NG V IID VL VP + +  K     L +    SD     + S   D   N+  ++   +P ++   W + +  Y
Sbjct:  291 IVKANIPVSNGVVHLIHRPLM------IIDTTVTQFLQENAENGALRKFYEVIMDNGGAVLDDINSLTEVTILAPSNEAWNSSNINNVLRDRNKMRQILNMHIIKDRLNVDKIRQKNANLIAQVPTVNNNTFLYFNVRGEGSDTVITVEGGGVNATVIQADVAQTNGYVHIIDHVLGVPYTTVLGK-----LESDPMMSDTYKMGKFSHFNDQLNNTQRRFTYFVPRDKG--WQKTELDY 517          
BLAST of Periostin vs. Ensembl Fly
Match: Fas1 (gene:FBgn0285925 transcript:FBtr0300037)

HSP 1 Score: 50.447 bits (119), Expect = 5.880e-6
Identity = 56/231 (24.24%), Postives = 96/231 (41.56%), Query Frame = 1
Query:  793 NGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNS---FYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKS----KYGSKISLLVKNHILNRMICAQAITKKATSL---GPSLANE---YLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVL-VPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKY 1443
            NGV+H I  P+           TV Q +Q +    +   FY  I      +LD  +    +T+ APSN AW ++      +  +K+  ++  HI+   +    I +K  +L    P++ N    Y  V      +   ++  G  A +I+ D+   NG V IID VL VP + +  K     L +    SD     + S   D   N+  ++   +P ++   W + +  Y
Sbjct:  300 NGVVHLIHRPLM------IIDTTVTQFLQENAENGALRKFYEVIMDNGGAVLDDINSLTEVTILAPSNEAWNSSNINNVLRDRNKMRQILNMHIIKDRLNVDKIRQKNANLIAQVPTVNNNTFLYFNVRGEGSDTVITVEGGGVNATVIQADVAQTNGYVHIIDHVLGVPYTTVLGK-----LESDPMMSDTYKMGKFSHFNDQLNNTQRRFTYFVPRDKG--WQKTELDY 517          
BLAST of Periostin vs. Ensembl Fly
Match: Fas1 (gene:FBgn0285925 transcript:FBtr0300036)

HSP 1 Score: 50.447 bits (119), Expect = 5.932e-6
Identity = 56/231 (24.24%), Postives = 96/231 (41.56%), Query Frame = 1
Query:  793 NGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNS---FYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKS----KYGSKISLLVKNHILNRMICAQAITKKATSL---GPSLANE---YLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVL-VPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKY 1443
            NGV+H I  P+           TV Q +Q +    +   FY  I      +LD  +    +T+ APSN AW ++      +  +K+  ++  HI+   +    I +K  +L    P++ N    Y  V      +   ++  G  A +I+ D+   NG V IID VL VP + +  K     L +    SD     + S   D   N+  ++   +P ++   W + +  Y
Sbjct:  300 NGVVHLIHRPLM------IIDTTVTQFLQENAENGALRKFYEVIMDNGGAVLDDINSLTEVTILAPSNEAWNSSNINNVLRDRNKMRQILNMHIIKDRLNVDKIRQKNANLIAQVPTVNNNTFLYFNVRGEGSDTVITVEGGGVNATVIQADVAQTNGYVHIIDHVLGVPYTTVLGK-----LESDPMMSDTYKMGKFSHFNDQLNNTQRRFTYFVPRDKG--WQKTELDY 517          
BLAST of Periostin vs. Ensembl Fly
Match: mfas (gene:FBgn0260745 transcript:FBtr0082491)

HSP 1 Score: 50.447 bits (119), Expect = 6.119e-6
Identity = 104/554 (18.77%), Postives = 214/554 (38.63%), Query Frame = 1
Query:  355 TFEYQCCPGFTKSPLVD--NQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEF--------DLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTY----SNGL----VFIDCRALVNPDHEAKNGVIHYISG---PITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE--------AAKSKYGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCS---SDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSF--LQHSRSCDLKINSFSKYILLIPTNEA------HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWGS 1896
            T   QCC G+ +    D    C +++   K +     D    +F +      ++ D+         T+  P     M+            D       P    +H     +      N    +T   D K+++ +Y    + GL       +C  +   D  ++  ++H + G   P+T ++    + +  +  M+            ++ L  ML+   D + +T+F P++ A++        A K   G   ++L KNH+L+   C+ A    A +   +L  E L ++ +   ++++        N A+II  D++  NGV+ +ID++L   SA+        +++  S+ +++ F  L  +   D + +      +  PT++A         L+EQ +  N N  +        + L YHV+K    T   +++ S  +   +  +     T+ +     ++   N AR    +       ++  VDR   PP   M++LL   P+     E ++       + +   ++  L  +N  ++   E   GS
Sbjct:  186 TLTRQCCYGYGRPRNADFTTPCEKID--IKDVEATASDMGAKQFLESARTAGELADMLGAGSGKKVTLFVPNDAAFMEYRGHHQQENNVEDAKAEASKPSIYKLHAVLGEVQLEDVPNEKLLQTELPDQKIRINSYQLPAALGLEPYRFAANCVPIEKHDKLSEQALVHTLGGVLKPLTKNLMDIIRERADMSIMRTVLE--------KTNLSAMLE---DDKPVTIFVPTDAAFDKLEPHLRRALKEGRGCASNIL-KNHLLDLTFCSLATVPGAKTTAYNLLGEPLLLNRTHRAANQTGPTPIYINNLAKIIDADIMGTNGVLHVIDTILPTESALP-------MTSLMSQKNLTIFQRLLEASGYDDQFDDLDNVTIFAPTDKALQNTEWARMLKEQPELLNHNLDL-------LEFLNYHVVKPMIKT-CDLSEKSLPTVAGSSVRLNLYSTHALFSDVMNRATVNCARLVHFDDESCG-SVLHQVDRALAPPKNNMLKLLEANPNYSKFLELVRKANLTQLLSNDSRSLTLLVPKNDIFEELNESGEGS 709          
BLAST of Periostin vs. Ensembl Fly
Match: mfas (gene:FBgn0260745 transcript:FBtr0082492)

HSP 1 Score: 50.447 bits (119), Expect = 6.119e-6
Identity = 104/554 (18.77%), Postives = 214/554 (38.63%), Query Frame = 1
Query:  355 TFEYQCCPGFTKSPLVD--NQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEF--------DLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTY----SNGL----VFIDCRALVNPDHEAKNGVIHYISG---PITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE--------AAKSKYGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCS---SDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSF--LQHSRSCDLKINSFSKYILLIPTNEA------HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWGS 1896
            T   QCC G+ +    D    C +++   K +     D    +F +      ++ D+         T+  P     M+            D       P    +H     +      N    +T   D K+++ +Y    + GL       +C  +   D  ++  ++H + G   P+T ++    + +  +  M+            ++ L  ML+   D + +T+F P++ A++        A K   G   ++L KNH+L+   C+ A    A +   +L  E L ++ +   ++++        N A+II  D++  NGV+ +ID++L   SA+        +++  S+ +++ F  L  +   D + +      +  PT++A         L+EQ +  N N  +        + L YHV+K    T   +++ S  +   +  +     T+ +     ++   N AR    +       ++  VDR   PP   M++LL   P+     E ++       + +   ++  L  +N  ++   E   GS
Sbjct:  186 TLTRQCCYGYGRPRNADFTTPCEKID--IKDVEATASDMGAKQFLESARTAGELADMLGAGSGKKVTLFVPNDAAFMEYRGHHQQENNVEDAKAEASKPSIYKLHAVLGEVQLEDVPNEKLLQTELPDQKIRINSYQLPAALGLEPYRFAANCVPIEKHDKLSEQALVHTLGGVLKPLTKNLMDIIRERADMSIMRTVLE--------KTNLSAMLE---DDKPVTIFVPTDAAFDKLEPHLRRALKEGRGCASNIL-KNHLLDLTFCSLATVPGAKTTAYNLLGEPLLLNRTHRAANQTGPTPIYINNLAKIIDADIMGTNGVLHVIDTILPTESALP-------MTSLMSQKNLTIFQRLLEASGYDDQFDDLDNVTIFAPTDKALQNTEWARMLKEQPELLNHNLDL-------LEFLNYHVVKPMIKT-CDLSEKSLPTVAGSSVRLNLYSTHALFSDVMNRATVNCARLVHFDDESCG-SVLHQVDRALAPPKNNMLKLLEANPNYSKFLELVRKANLTQLLSNDSRSLTLLVPKNDIFEELNESGEGS 709          
BLAST of Periostin vs. Ensembl Zebrafish
Match: postnb (periostin, osteoblast specific factor b [Source:ZFIN;Acc:ZDB-GENE-030131-9120])

HSP 1 Score: 111.309 bits (277), Expect = 1.107e-24
Identity = 115/400 (28.75%), Postives = 181/400 (45.25%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYSDDAMKLGEFDL-----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAW-----EAAKSKYGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA 1413
            N+CA L+   G     F TC   ++   C    T  Y+CCPG+ +       C  V  +  +         + K AK  + +S I  L +E  G  +YT  AP S+DA  L E ++     SNV     + +  H+   R+ +    NG T  ++ +D  L +  YSNG+V ++C  +++ +  A NGV+H I   IT  VGS  Q    ++    D L+        S L   +D+  +    T+FAP+N A+     E        K SL  L+  H+LN + C++AI   A +   +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P SA    + V     G S++  S  L         +   ++Y LL P N A
Sbjct:   42 NMCA-LQQVVGTKKKYFSTCRNWYQGAICGKTATVLYECCPGYMELA-GQRGCPAVAPIDNV----FGTLGLVK-AKTTQDYSDISKLRQEIEGAGSYTFFAP-SNDAWDLLEAEVRNALVSNVNIELYNALHYHMVNKRLLTKDLKNGMTATSMYNDLSLHINHYSNGVVTVNCARIIHGNQVATNGVVHVIDRVITA-VGSTIQDMIEVE----DDLSTLSTVATDSGL---IDKLGEPGHFTLFAPTNAAFDKLGREVLDRLMKDKKSLQALLNYHLLNSVQCSEAIM--AGTSHETLEGSNIEIGCDGDS----LTVNGIKM-VLKKDIVATNGVIHLIDEVLMPDSAKQVMELV-----GQSQATFSDMLTE-LGLSAAMRPQAEYTLLAPVNAA 412          

HSP 2 Score: 58.151 bits (139), Expect = 3.944e-8
Identity = 66/271 (24.35%), Postives = 117/271 (43.17%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQR-------KTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSK-------YGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSA-MSAKDAVSCL 1299
            YT+LAP    ++D+ M + +  L  +      +  HI KN++  +Q  NG   +TLS    L+V  Y   L  I+   L+    E  NG +H +   I+P   S +Q        K  L  M+   LT            ++L QE D    T+FAP++ A+     +        G+ +  ++  H  N +     +    T+L  +L    L V   ++ S  +     N  ++ + D+++ NGVV  + ++L P    + ++D +S L
Sbjct:  403 YTLLAPVNAAFNDEVMSMDQSFLKII------LENHILKNKIVLSQLYNGQRLETLSGKF-LRVFVYRTALC-IENACLIRGSKEGSNGALHLMKTLISPAESSMFQILVKNGAFKIFLSLMEAAGLT------------DLLKQEGD---FTLFAPTDEAFAGLSERDLTLLKSNGNALKAILLYHFSNGVFIGGGLETGVTNLLKTLQGSNLRV-LYANASMLV-----NTVKVPEPDIMATNGVVHFVRTLLYPEDIPVGSQDLLSLL 644          
BLAST of Periostin vs. Ensembl Zebrafish
Match: postnb (periostin, osteoblast specific factor b [Source:ZFIN;Acc:ZDB-GENE-030131-9120])

HSP 1 Score: 111.309 bits (277), Expect = 1.174e-24
Identity = 115/400 (28.75%), Postives = 181/400 (45.25%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYSDDAMKLGEFDL-----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAW-----EAAKSKYGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA 1413
            N+CA L+   G     F TC   ++   C    T  Y+CCPG+ +       C  V  +  +         + K AK  + +S I  L +E  G  +YT  AP S+DA  L E ++     SNV     + +  H+   R+ +    NG T  ++ +D  L +  YSNG+V ++C  +++ +  A NGV+H I   IT  VGS  Q    ++    D L+        S L   +D+  +    T+FAP+N A+     E        K SL  L+  H+LN + C++AI   A +   +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P SA    + V     G S++  S  L         +   ++Y LL P N A
Sbjct:   42 NMCA-LQQVVGTKKKYFSTCRNWYQGAICGKTATVLYECCPGYMELA-GQRGCPAVAPIDNV----FGTLGLVK-AKTTQDYSDISKLRQEIEGAGSYTFFAP-SNDAWDLLEAEVRNALVSNVNIELYNALHYHMVNKRLLTKDLKNGMTATSMYNDLSLHINHYSNGVVTVNCARIIHGNQVATNGVVHVIDRVITA-VGSTIQDMIEVE----DDLSTLSTVATDSGL---IDKLGEPGHFTLFAPTNAAFDKLGREVLDRLMKDKKSLQALLNYHLLNSVQCSEAIM--AGTSHETLEGSNIEIGCDGDS----LTVNGIKM-VLKKDIVATNGVIHLIDEVLMPDSAKQVMELV-----GQSQATFSDMLTE-LGLSAAMRPQAEYTLLAPVNAA 412          

HSP 2 Score: 58.151 bits (139), Expect = 3.518e-8
Identity = 66/271 (24.35%), Postives = 117/271 (43.17%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQR-------KTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSK-------YGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSA-MSAKDAVSCL 1299
            YT+LAP    ++D+ M + +  L  +      +  HI KN++  +Q  NG   +TLS    L+V  Y   L  I+   L+    E  NG +H +   I+P   S +Q        K  L  M+   LT            ++L QE D    T+FAP++ A+     +        G+ +  ++  H  N +     +    T+L  +L    L V   ++ S  +     N  ++ + D+++ NGVV  + ++L P    + ++D +S L
Sbjct:  403 YTLLAPVNAAFNDEVMSMDQSFLKII------LENHILKNKIVLSQLYNGQRLETLSGKF-LRVFVYRTALC-IENACLIRGSKEGSNGALHLMKTLISPAESSMFQILVKNGAFKIFLSLMEAAGLT------------DLLKQEGD---FTLFAPTDEAFAGLSERDLTLLKSNGNALKAILLYHFSNGVFIGGGLETGVTNLLKTLQGSNLRV-LYANASMLV-----NTVKVPEPDIMATNGVVHFVRTLLYPEDIPVGSQDLLSLL 644          
BLAST of Periostin vs. Ensembl Zebrafish
Match: postnb (periostin, osteoblast specific factor b [Source:ZFIN;Acc:ZDB-GENE-030131-9120])

HSP 1 Score: 110.923 bits (276), Expect = 1.322e-24
Identity = 115/400 (28.75%), Postives = 181/400 (45.25%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYSDDAMKLGEFDL-----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAW-----EAAKSKYGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA 1413
            N+CA L+   G     F TC   ++   C    T  Y+CCPG+ +       C  V  +  +         + K AK  + +S I  L +E  G  +YT  AP S+DA  L E ++     SNV     + +  H+   R+ +    NG T  ++ +D  L +  YSNG+V ++C  +++ +  A NGV+H I   IT  VGS  Q    ++    D L+        S L   +D+  +    T+FAP+N A+     E        K SL  L+  H+LN + C++AI   A +   +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P SA    + V     G S++  S  L         +   ++Y LL P N A
Sbjct:   42 NMCA-LQQVVGTKKKYFSTCRNWYQGAICGKTATVLYECCPGYMELA-GQRGCPAVAPIDNV----FGTLGLVK-AKTTQDYSDISKLRQEIEGAGSYTFFAP-SNDAWDLLEAEVRNALVSNVNIELYNALHYHMVNKRLLTKDLKNGMTATSMYNDLSLHINHYSNGVVTVNCARIIHGNQVATNGVVHVIDRVITA-VGSTIQDMIEVE----DDLSTLSTVATDSGL---IDKLGEPGHFTLFAPTNAAFDKLGREVLDRLMKDKKSLQALLNYHLLNSVQCSEAIM--AGTSHETLEGSNIEIGCDGDS----LTVNGIKM-VLKKDIVATNGVIHLIDEVLMPDSAKQVMELV-----GQSQATFSDMLTE-LGLSAAMRPQAEYTLLAPVNAA 412          

HSP 2 Score: 58.151 bits (139), Expect = 3.905e-8
Identity = 66/271 (24.35%), Postives = 117/271 (43.17%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQR-------KTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSK-------YGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSA-MSAKDAVSCL 1299
            YT+LAP    ++D+ M + +  L  +      +  HI KN++  +Q  NG   +TLS    L+V  Y   L  I+   L+    E  NG +H +   I+P   S +Q        K  L  M+   LT            ++L QE D    T+FAP++ A+     +        G+ +  ++  H  N +     +    T+L  +L    L V   ++ S  +     N  ++ + D+++ NGVV  + ++L P    + ++D +S L
Sbjct:  403 YTLLAPVNAAFNDEVMSMDQSFLKII------LENHILKNKIVLSQLYNGQRLETLSGKF-LRVFVYRTALC-IENACLIRGSKEGSNGALHLMKTLISPAESSMFQILVKNGAFKIFLSLMEAAGLT------------DLLKQEGD---FTLFAPTDEAFAGLSERDLTLLKSNGNALKAILLYHFSNGVFIGGGLETGVTNLLKTLQGSNLRV-LYANASMLV-----NTVKVPEPDIMATNGVVHFVRTLLYPEDIPVGSQDLLSLL 644          
BLAST of Periostin vs. Ensembl Zebrafish
Match: postnb (periostin, osteoblast specific factor b [Source:ZFIN;Acc:ZDB-GENE-030131-9120])

HSP 1 Score: 110.923 bits (276), Expect = 1.326e-24
Identity = 115/400 (28.75%), Postives = 181/400 (45.25%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYSDDAMKLGEFDL-----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAW-----EAAKSKYGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA 1413
            N+CA L+   G     F TC   ++   C    T  Y+CCPG+ +       C  V  +  +         + K AK  + +S I  L +E  G  +YT  AP S+DA  L E ++     SNV     + +  H+   R+ +    NG T  ++ +D  L +  YSNG+V ++C  +++ +  A NGV+H I   IT  VGS  Q    ++    D L+        S L   +D+  +    T+FAP+N A+     E        K SL  L+  H+LN + C++AI   A +   +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P SA    + V     G S++  S  L         +   ++Y LL P N A
Sbjct:   42 NMCA-LQQVVGTKKKYFSTCRNWYQGAICGKTATVLYECCPGYMELA-GQRGCPAVAPIDNV----FGTLGLVK-AKTTQDYSDISKLRQEIEGAGSYTFFAP-SNDAWDLLEAEVRNALVSNVNIELYNALHYHMVNKRLLTKDLKNGMTATSMYNDLSLHINHYSNGVVTVNCARIIHGNQVATNGVVHVIDRVITA-VGSTIQDMIEVE----DDLSTLSTVATDSGL---IDKLGEPGHFTLFAPTNAAFDKLGREVLDRLMKDKKSLQALLNYHLLNSVQCSEAIM--AGTSHETLEGSNIEIGCDGDS----LTVNGIKM-VLKKDIVATNGVIHLIDEVLMPDSAKQVMELV-----GQSQATFSDMLTE-LGLSAAMRPQAEYTLLAPVNAA 412          

HSP 2 Score: 58.151 bits (139), Expect = 3.732e-8
Identity = 66/271 (24.35%), Postives = 117/271 (43.17%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQR-------KTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSK-------YGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSA-MSAKDAVSCL 1299
            YT+LAP    ++D+ M + +  L  +      +  HI KN++  +Q  NG   +TLS    L+V  Y   L  I+   L+    E  NG +H +   I+P   S +Q        K  L  M+   LT            ++L QE D    T+FAP++ A+     +        G+ +  ++  H  N +     +    T+L  +L    L V   ++ S  +     N  ++ + D+++ NGVV  + ++L P    + ++D +S L
Sbjct:  403 YTLLAPVNAAFNDEVMSMDQSFLKII------LENHILKNKIVLSQLYNGQRLETLSGKF-LRVFVYRTALC-IENACLIRGSKEGSNGALHLMKTLISPAESSMFQILVKNGAFKIFLSLMEAAGLT------------DLLKQEGD---FTLFAPTDEAFAGLSERDLTLLKSNGNALKAILLYHFSNGVFIGGGLETGVTNLLKTLQGSNLRV-LYANASMLV-----NTVKVPEPDIMATNGVVHFVRTLLYPEDIPVGSQDLLSLL 644          
BLAST of Periostin vs. Ensembl Zebrafish
Match: postna (periostin, osteoblast specific factor a [Source:ZFIN;Acc:ZDB-GENE-091113-23])

HSP 1 Score: 110.153 bits (274), Expect = 1.946e-24
Identity = 108/412 (26.21%), Postives = 195/412 (47.33%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTK------SPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDA------------MKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQ-NDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSK-------ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA 1413
            N+CA L+   G     F TC   +K++ C  +    Y+CCPG+ K       P V    + ++SV+  + + +K  +  ++A      S++++  E  G  +YT+ AP SDDA            + LG  +L N       +  H+   R  +    N  T +++ +   L +  YSNG+V ++C  +++ +  A NGV+H I   I+         +T+   ++ ND L++     + ++L++ L +   G + T+FAP+N A++   +    +       I  L+K H+LN + C++AI   A S+  +L    + + C  +     L   G K  ++K+D+V+ NGV+ +ID VL+P SA    + V     G S+S V S +         +   ++Y +L P N A
Sbjct:   42 NVCA-LQQVMGTKKKYFSTCRNWYKKSICGKKAIVLYECCPGYMKLEGKRGCPAV----APIDSVYGTLDL-VKAKTTQQYAD----QSKLRE--EIAGEGSYTIFAP-SDDAWEELDPASKAAVISLGNTELYN------ALHYHMVSKRFLTKDLKNDMTLESMFNKQGLHINHYSNGVVTVNCARIIHGNQVATNGVVHVIDRVIS------VVSQTIKDVIETNDDLSSLSGVVVSADLQDQLGEP--GHY-TLFAPTNEAFDKINADALERLMSDQTVIQALLKYHLLNSVQCSEAIM--AGSIYGTLEGSNIEIGCDGES----LTVNGIKM-VLKKDIVTSNGVIHLIDQVLMPDSAKQVMELV-----GKSQS-VFSDMVSELGLSAALQPETEYTVLAPLNGA 412          
BLAST of Periostin vs. Ensembl Xenopus
Match: postn (periostin, osteoblast specific factor [Source:NCBI gene;Acc:100127174])

HSP 1 Score: 118.627 bits (296), Expect = 7.581e-27
Identity = 139/517 (26.89%), Postives = 235/517 (45.45%), Query Frame = 1
Query:  127 YLKMFAGFYILSVLLIVVNAQVNPKYPRYTPVAKELAQPFKETNLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTK------SPLVDNQCSEVESVWKIIPV----HLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFD-----LSNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQN-DPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSK--ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            +L +FA F    +L  + +A+ N  Y +    ++  A+  +  N+CA L+   G     F TC   ++   C  + T  Y+CCPG+ K       P V    + +++V+  + +      +DYS           S+++   E  G  +YT  AP S+DA +L + D     LSNV     + +  H+   RM +    NG +  ++ ++ +L +  Y+NG+V ++C  +++ +  A NGV+H I   +T  VG+     T+   +++ D LT+     + +E+   L ++  GQ+ T+FAP+N A+E       +   G K  +  LV  HILN + C++AI     SL  +L    L + C  D     L   GNK  + ++D+V+ NGV+ +ID VL+P SA         L    S+    + L             ++Y LL P N A +   E  K      ++         +L+ HVLK K       N  + ++    GGK L V  Y
Sbjct:    5 FLCVFATF----LLSAIDHAEGNAYYDKILTHSRIRARQ-QGPNVCA-LQQVLGTKKKYFSTCKNWYQGAICGKKATILYECCPGYMKINGESGCPAV----APIDNVYGTLGIVGATSTQDYS---------DRSELRKEIE--GVGSYTFFAP-SNDAWQLLDSDVRDSLLSNVNIELLNALHYHMINKRMLTKDLKNGLSVTSMFNNQELVINHYTNGVVTVNCARVIHGNQIATNGVVHVIDRVVTA-VGN-----TIEDFIESEDELTSFREAGVAAEVLAELGKK--GQY-TLFAPTNDAFEKLPRGVLERIMGDKQAVKALVNYHILNSVQCSEAIM--GGSLLETLEGSSLQIGCDGDS----LTVNGNKM-VNRKDIVTTNGVIHLIDQVLIPDSAKQV------LELAGSEQTTFTDLMAQMGLAASFRPDAEYTLLAPINNAFS--DETLKMDQRILKL---------ILQNHVLKTKVALNGLYNGQTLET---LGGKLLRVFVY 463          

HSP 2 Score: 51.2174 bits (121), Expect = 7.366e-6
Identity = 72/301 (23.92%), Postives = 124/301 (41.20%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQ-SELREMLDQESDGQWLTVFAPSNTAWEAAKSK-----YGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNE 1410
            YT+LAP    +SD+ +K+ +  L  +      +  H+ K ++  N   NG T +TL     L+V  Y    V I+   ++    E +NG IH  S  I P        K+    +  D   + F N I+ + L+++L Q   G W T F P+N A++   ++        K++L  ++  H+   +          T++  SL    + V  + + + S+     N     + D ++ NGV  +ID +L P       + +  +     K     F   SR    K    +KYI  I   E
Sbjct:  404 YTLLAPINNAFSDETLKMDQRILKLI------LQNHVLKTKVALNGLYNGQTLETLGG-KLLRVFVYRTA-VCIENSCMLRGSKEGRNGAIHIFSEIIKP------AEKSFYDLLSLDKRFSIFLNLIEFAGLKDLLLQP--GAW-TWFIPTNDAFKGLSNEEMEILKRDKVALQNILLYHLAPEVFIGGGFEPGVTNILKSLQGNKIMVKAAVNNTLSV-----NGVVSKEPDQMTTNGVFHVIDKLLFPADVSLGNEQLLSILNKIIKYITIKF---SRGSTFKEIPLTKYIKFITIGE 679          
BLAST of Periostin vs. Ensembl Xenopus
Match: postn (periostin, osteoblast specific factor [Source:NCBI gene;Acc:100127174])

HSP 1 Score: 117.857 bits (294), Expect = 1.558e-26
Identity = 130/474 (27.43%), Postives = 215/474 (45.36%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTK------SPLVDNQCSEVESVWKIIPV----HLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFD-----LSNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQN-DPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSK--ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F TC   ++   C  + T  Y+CCPG+ K       P V    + +++V+  + +      +DYS           S+++   E  G  +YT  AP S+DA +L + D     LSNV     + +  H+   RM +    NG +  ++ ++ +L +  Y+NG+V ++C  +++ +  A NGV+H I   +T  VG+     T+   +++ D LT+     + +E+   L ++  GQ+ T+FAP+N A+E       +   G K  +  LV  HILN + C++AI     SL  +L    L + C  D     L   GNK  + ++D+V+ NGV+ +ID VL+P SA         L    S+    + L             ++Y LL P N A +   E  K      ++         +L+ HVLK K       N  + ++    GGK L V  Y
Sbjct:   44 NVCA-LQQVLGTKKKYFSTCKNWYQGAICGKKATILYECCPGYMKINGESGCPAV----APIDNVYGTLGIVGATSTQDYS---------DRSELRKEIE--GVGSYTFFAP-SNDAWQLLDSDVRDSLLSNVNIELLNALHYHMINKRMLTKDLKNGLSVTSMFNNQELVINHYTNGVVTVNCARVIHGNQIATNGVVHVIDRVVTA-VGN-----TIEDFIESEDELTSFREAGVAAEVLAELGKK--GQY-TLFAPTNDAFEKLPRGVLERIMGDKQAVKALVNYHILNSVQCSEAIM--GGSLLETLEGSSLQIGCDGDS----LTVNGNKM-VNRKDIVTTNGVIHLIDQVLIPDSAK------QVLELAGSEQTTFTDLMAQMGLAASFRPDAEYTLLAPINNAFS--DETLKMDQRILKL---------ILQNHVLKTKVALNGLYNGQTLET---LGGKLLRVFVY 464          

HSP 2 Score: 51.2174 bits (121), Expect = 8.316e-6
Identity = 73/301 (24.25%), Postives = 124/301 (41.20%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQ-SELREMLDQESDGQWLTVFAPSNTAWEAAKSK-----YGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNE 1410
            YT+LAP    +SD+ +K+ +  L  +      +  H+ K ++  N   NG T +TL     L+V  Y    V I+   ++    E +NG IH  S  I P   S Y        +  D   + F N I+ + L+++L Q   G W T F P+N A++   ++        K++L  ++  H+   +          T++  SL    + V  + + + S+     N     + D ++ NGV  +ID +L P       + +  +     K     F   SR    K    +KYI  I   E
Sbjct:  405 YTLLAPINNAFSDETLKMDQRILKLI------LQNHVLKTKVALNGLYNGQTLETLGGKL-LRVFVYRTA-VCIENSCMLRGSKEGRNGAIHIFSEIIKPAEKSFYD------LLSLDKRFSIFLNLIEFAGLKDLLLQ--PGAW-TWFIPTNDAFKGLSNEEMEILKRDKVALQNILLYHLAPEVFIGGGFEPGVTNILKSLQGNKIMVKAAVNNTLSV-----NGVVSKEPDQMTTNGVFHVIDKLLFPADVSLGNEQLLSILNKIIKYITIKF---SRGSTFKEIPLTKYIKFITIGE 680          
BLAST of Periostin vs. Ensembl Xenopus
Match: postn (periostin, osteoblast specific factor [Source:NCBI gene;Acc:100127174])

HSP 1 Score: 117.857 bits (294), Expect = 1.812e-26
Identity = 130/474 (27.43%), Postives = 215/474 (45.36%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTK------SPLVDNQCSEVESVWKIIPV----HLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFD-----LSNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQN-DPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSK--ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F TC   ++   C  + T  Y+CCPG+ K       P V    + +++V+  + +      +DYS           S+++   E  G  +YT  AP S+DA +L + D     LSNV     + +  H+   RM +    NG +  ++ ++ +L +  Y+NG+V ++C  +++ +  A NGV+H I   +T  VG+     T+   +++ D LT+     + +E+   L ++  GQ+ T+FAP+N A+E       +   G K  +  LV  HILN + C++AI     SL  +L    L + C  D     L   GNK  + ++D+V+ NGV+ +ID VL+P SA         L    S+    + L             ++Y LL P N A +   E  K      ++         +L+ HVLK K       N  + ++    GGK L V  Y
Sbjct:   44 NVCA-LQQVLGTKKKYFSTCKNWYQGAICGKKATILYECCPGYMKINGESGCPAV----APIDNVYGTLGIVGATSTQDYS---------DRSELRKEIE--GVGSYTFFAP-SNDAWQLLDSDVRDSLLSNVNIELLNALHYHMINKRMLTKDLKNGLSVTSMFNNQELVINHYTNGVVTVNCARVIHGNQIATNGVVHVIDRVVTA-VGN-----TIEDFIESEDELTSFREAGVAAEVLAELGKK--GQY-TLFAPTNDAFEKLPRGVLERIMGDKQAVKALVNYHILNSVQCSEAIM--GGSLLETLEGSSLQIGCDGDS----LTVNGNKM-VNRKDIVTTNGVIHLIDQVLIPDSAK------QVLELAGSEQTTFTDLMAQMGLAASFRPDAEYTLLAPINNAFS--DETLKMDQRILKL---------ILQNHVLKTKVALNGLYNGQTLET---LGGKLLRVFVY 464          

HSP 2 Score: 50.8322 bits (120), Expect = 9.255e-6
Identity = 72/301 (23.92%), Postives = 123/301 (40.86%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQ-SELREMLDQESDGQWLTVFAPSNTAWEAAKSK-----YGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNE 1410
            YT+LAP    +SD+ +K+ +  L  +      +  H+ K ++  N   NG T +TL     L+V  Y    V I+   ++    E +NG IH  S  I P   S Y        +  D   + F N I+ + L+++L Q   G W T F P+N A++   ++        K++L  ++  H+   +          T++  SL    + V  + + + S+      +      D ++ NGV  +ID +L P       + +  +     K     F   SR    K    +KYI  I   E
Sbjct:  405 YTLLAPINNAFSDETLKMDQRILKLI------LQNHVLKTKVALNGLYNGQTLETLGGKL-LRVFVYRTA-VCIENSCMLRGSKEGRNGAIHIFSEIIKPAEKSFYD------LLSLDKRFSIFLNLIEFAGLKDLLLQ--PGAW-TWFIPTNDAFKGLSNEEMEILKRDKVALQNILLYHLAPEVFIGGGFEPGVTNILKSLQGNKIMVKAAVNNTLSVNGVVSKEP-----DQMTTNGVFHVIDKLLFPADVSLGNEQLLSILNKIIKYITIKF---SRGSTFKEIPLTKYIKFITIGE 680          
BLAST of Periostin vs. Ensembl Xenopus
Match: postn (periostin, osteoblast specific factor [Source:NCBI gene;Acc:100127174])

HSP 1 Score: 117.857 bits (294), Expect = 1.844e-26
Identity = 130/474 (27.43%), Postives = 215/474 (45.36%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTK------SPLVDNQCSEVESVWKIIPV----HLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFD-----LSNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQN-DPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSK--ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F TC   ++   C  + T  Y+CCPG+ K       P V    + +++V+  + +      +DYS           S+++   E  G  +YT  AP S+DA +L + D     LSNV     + +  H+   RM +    NG +  ++ ++ +L +  Y+NG+V ++C  +++ +  A NGV+H I   +T  VG+     T+   +++ D LT+     + +E+   L ++  GQ+ T+FAP+N A+E       +   G K  +  LV  HILN + C++AI     SL  +L    L + C  D     L   GNK  + ++D+V+ NGV+ +ID VL+P SA         L    S+    + L             ++Y LL P N A +   E  K      ++         +L+ HVLK K       N  + ++    GGK L V  Y
Sbjct:   44 NVCA-LQQVLGTKKKYFSTCKNWYQGAICGKKATILYECCPGYMKINGESGCPAV----APIDNVYGTLGIVGATSTQDYS---------DRSELRKEIE--GVGSYTFFAP-SNDAWQLLDSDVRDSLLSNVNIELLNALHYHMINKRMLTKDLKNGLSVTSMFNNQELVINHYTNGVVTVNCARVIHGNQIATNGVVHVIDRVVTA-VGN-----TIEDFIESEDELTSFREAGVAAEVLAELGKK--GQY-TLFAPTNDAFEKLPRGVLERIMGDKQAVKALVNYHILNSVQCSEAIM--GGSLLETLEGSSLQIGCDGDS----LTVNGNKM-VNRKDIVTTNGVIHLIDQVLIPDSAK------QVLELAGSEQTTFTDLMAQMGLAASFRPDAEYTLLAPINNAFS--DETLKMDQRILKL---------ILQNHVLKTKVALNGLYNGQTLET---LGGKLLRVFVY 464          

HSP 2 Score: 50.8322 bits (120), Expect = 9.192e-6
Identity = 72/301 (23.92%), Postives = 123/301 (40.86%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQ-SELREMLDQESDGQWLTVFAPSNTAWEAAKSK-----YGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNE 1410
            YT+LAP    +SD+ +K+ +  L  +      +  H+ K ++  N   NG T +TL     L+V  Y    V I+   ++    E +NG IH  S  I P   S Y        +  D   + F N I+ + L+++L Q   G W T F P+N A++   ++        K++L  ++  H+   +          T++  SL    + V  + + + S+      +      D ++ NGV  +ID +L P       + +  +     K     F   SR    K    +KYI  I   E
Sbjct:  405 YTLLAPINNAFSDETLKMDQRILKLI------LQNHVLKTKVALNGLYNGQTLETLGGKL-LRVFVYRTA-VCIENSCMLRGSKEGRNGAIHIFSEIIKPAEKSFYD------LLSLDKRFSIFLNLIEFAGLKDLLLQ--PGAW-TWFIPTNDAFKGLSNEEMEILKRDKVALQNILLYHLAPEVFIGGGFEPGVTNILKSLQGNKIMVKAAVNNTLSVNGVVSKEP-----DQMTTNGVFHVIDKLLFPADVSLGNEQLLSILNKIIKYITIKF---SRGSTFKEIPLTKYIKFITIGE 680          
BLAST of Periostin vs. Ensembl Xenopus
Match: postn (periostin, osteoblast specific factor [Source:NCBI gene;Acc:100127174])

HSP 1 Score: 117.857 bits (294), Expect = 1.908e-26
Identity = 130/474 (27.43%), Postives = 215/474 (45.36%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTK------SPLVDNQCSEVESVWKIIPV----HLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFD-----LSNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQN-DPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSK--ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F TC   ++   C  + T  Y+CCPG+ K       P V    + +++V+  + +      +DYS           S+++   E  G  +YT  AP S+DA +L + D     LSNV     + +  H+   RM +    NG +  ++ ++ +L +  Y+NG+V ++C  +++ +  A NGV+H I   +T  VG+     T+   +++ D LT+     + +E+   L ++  GQ+ T+FAP+N A+E       +   G K  +  LV  HILN + C++AI     SL  +L    L + C  D     L   GNK  + ++D+V+ NGV+ +ID VL+P SA         L    S+    + L             ++Y LL P N A +   E  K      ++         +L+ HVLK K       N  + ++    GGK L V  Y
Sbjct:   44 NVCA-LQQVLGTKKKYFSTCKNWYQGAICGKKATILYECCPGYMKINGESGCPAV----APIDNVYGTLGIVGATSTQDYS---------DRSELRKEIE--GVGSYTFFAP-SNDAWQLLDSDVRDSLLSNVNIELLNALHYHMINKRMLTKDLKNGLSVTSMFNNQELVINHYTNGVVTVNCARVIHGNQIATNGVVHVIDRVVTA-VGN-----TIEDFIESEDELTSFREAGVAAEVLAELGKK--GQY-TLFAPTNDAFEKLPRGVLERIMGDKQAVKALVNYHILNSVQCSEAIM--GGSLLETLEGSSLQIGCDGDS----LTVNGNKM-VNRKDIVTTNGVIHLIDQVLIPDSAK------QVLELAGSEQTTFTDLMAQMGLAASFRPDAEYTLLAPINNAFS--DETLKMDQRILKL---------ILQNHVLKTKVALNGLYNGQTLET---LGGKLLRVFVY 464          

HSP 2 Score: 50.8322 bits (120), Expect = 8.896e-6
Identity = 73/301 (24.25%), Postives = 124/301 (41.20%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQ-SELREMLDQESDGQWLTVFAPSNTAWEAAKSK-----YGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNE 1410
            YT+LAP    +SD+ +K+ +  L  +      +  H+ K ++  N   NG T +TL     L+V  Y    V I+   ++    E +NG IH  S  I P   S Y        +  D   + F N I+ + L+++L Q   G W T F P+N A++   ++        K++L  ++  H+   +          T++  SL    + V  + + + S+     N     + D ++ NGV  +ID +L P       + +  +     K     F   SR    K    +KYI  I   E
Sbjct:  405 YTLLAPINNAFSDETLKMDQRILKLI------LQNHVLKTKVALNGLYNGQTLETLGGKL-LRVFVYRTA-VCIENSCMLRGSKEGRNGAIHIFSEIIKPAEKSFYD------LLSLDKRFSIFLNLIEFAGLKDLLLQ--PGAW-TWFIPTNDAFKGLSNEEMEILKRDKVALQNILLYHLAPEVFIGGGFEPGVTNILKSLQGNKIMVKAAVNNTLSV-----NGVVSKEPDQMTTNGVFHVIDKLLFPADVSLGNEQLLSILNKIIKYITIKF---SRGSTFKEIPLTKYIKFITIGE 680          
BLAST of Periostin vs. Ensembl Mouse
Match: Postn (periostin, osteoblast specific factor [Source:MGI Symbol;Acc:MGI:1926321])

HSP 1 Score: 111.309 bits (277), Expect = 1.231e-24
Identity = 124/469 (26.44%), Postives = 213/469 (45.42%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYS------DDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARII-KEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F +C   ++   C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   + +S +  L EE  G+ +YT  AP +      D  ++ G  +  NV    + +  H+   RM +    +G    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    L+A   D L++     I S+L E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C++AIT  A     ++    + + C  D S SI     N  +++ K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + S    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   44 NVCA-LQQILGTKKKYFSSCKNWYQGAICGKKTTVLYECCPGYMR-------MEGMKGCPAVMPIDHVYGTLGIVGATTTQHYSDVSKLREEIEGKGSYTYFAPSNEAWENLDSDIRRGLENNVNVE-LLNALHSHMVNKRMLTKDLKHGMVIPSMYNNLGLFINHYPNGVVTVNCARVIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFLEA--EDDLSSFRAAAITSDLLESLGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITGGAVF--ETMEGNTIEIGCEGD-SISI-----NGIKMVNKKDIVTKNGVIHLIDEVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASS----LKPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLSDLYNGQILET---IGGKQLRVFVY 464          

HSP 2 Score: 51.6026 bits (122), Expect = 3.956e-6
Identity = 63/263 (23.95%), Postives = 118/263 (44.87%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQS-ELREMLDQESDGQWLTVFAPSNTAWEAAKSK-----YGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKE------DLVSGNGVVQIIDSVLVPTSAMSAKD 1284
            YT+LAP    +SDD + + +  L  +      +  HI K ++  +   NG   +T+    +L+V  Y    + I+   +V    + +NG IH     I P        K++   ++ D   + F + +++ +L+++L Q  D  W T+FAP+N A++   S+      G K +L  +N IL  +     I K      P + N    +  ++  S+  L    N+  ++ E      D+++ NGV+ ++D +L P       D
Sbjct:  405 YTLLAPVNNAFSDDTLSMDQRLLKLI------LQNHILKVKVGLSDLYNGQILETIGG-KQLRVFVYRTA-ICIENSCMVRGSKQGRNGAIHIFREIIQP------AEKSLHDKLRQDKRFSIFLSLLEAADLKDLLTQPGD--W-TLFAPTNDAFKGMTSEERELLIGDKNAL--QNIILYHLTPGVYIGK---GFEPGVTN----ILKTTQGSKIYLKGV-NETLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGND 640          
BLAST of Periostin vs. Ensembl Mouse
Match: Postn (periostin, osteoblast specific factor [Source:MGI Symbol;Acc:MGI:1926321])

HSP 1 Score: 110.923 bits (276), Expect = 1.524e-24
Identity = 124/469 (26.44%), Postives = 213/469 (45.42%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYS------DDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARII-KEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F +C   ++   C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   + +S +  L EE  G+ +YT  AP +      D  ++ G  +  NV    + +  H+   RM +    +G    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    L+A   D L++     I S+L E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C++AIT  A     ++    + + C  D S SI     N  +++ K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + S    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   44 NVCA-LQQILGTKKKYFSSCKNWYQGAICGKKTTVLYECCPGYMR-------MEGMKGCPAVMPIDHVYGTLGIVGATTTQHYSDVSKLREEIEGKGSYTYFAPSNEAWENLDSDIRRGLENNVNVE-LLNALHSHMVNKRMLTKDLKHGMVIPSMYNNLGLFINHYPNGVVTVNCARVIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFLEA--EDDLSSFRAAAITSDLLESLGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITGGAVF--ETMEGNTIEIGCEGD-SISI-----NGIKMVNKKDIVTKNGVIHLIDEVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASS----LKPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLSDLYNGQILET---IGGKQLRVFVY 464          

HSP 2 Score: 51.2174 bits (121), Expect = 4.600e-6
Identity = 63/263 (23.95%), Postives = 118/263 (44.87%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQS-ELREMLDQESDGQWLTVFAPSNTAWEAAKSK-----YGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKE------DLVSGNGVVQIIDSVLVPTSAMSAKD 1284
            YT+LAP    +SDD + + +  L  +      +  HI K ++  +   NG   +T+    +L+V  Y    + I+   +V    + +NG IH     I P        K++   ++ D   + F + +++ +L+++L Q  D  W T+FAP+N A++   S+      G K +L  +N IL  +     I K      P + N    +  ++  S+  L    N+  ++ E      D+++ NGV+ ++D +L P       D
Sbjct:  405 YTLLAPVNNAFSDDTLSMDQRLLKLI------LQNHILKVKVGLSDLYNGQILETIGG-KQLRVFVYRTA-ICIENSCMVRGSKQGRNGAIHIFREIIQP------AEKSLHDKLRQDKRFSIFLSLLEAADLKDLLTQPGD--W-TLFAPTNDAFKGMTSEERELLIGDKNAL--QNIILYHLTPGVYIGK---GFEPGVTN----ILKTTQGSKIYLKGV-NETLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGND 640          
BLAST of Periostin vs. Ensembl Mouse
Match: Postn (periostin, osteoblast specific factor [Source:MGI Symbol;Acc:MGI:1926321])

HSP 1 Score: 110.923 bits (276), Expect = 1.753e-24
Identity = 124/469 (26.44%), Postives = 213/469 (45.42%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYS------DDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARII-KEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F +C   ++   C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   + +S +  L EE  G+ +YT  AP +      D  ++ G  +  NV    + +  H+   RM +    +G    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    L+A   D L++     I S+L E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C++AIT  A     ++    + + C  D S SI     N  +++ K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + S    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   44 NVCA-LQQILGTKKKYFSSCKNWYQGAICGKKTTVLYECCPGYMR-------MEGMKGCPAVMPIDHVYGTLGIVGATTTQHYSDVSKLREEIEGKGSYTYFAPSNEAWENLDSDIRRGLENNVNVE-LLNALHSHMVNKRMLTKDLKHGMVIPSMYNNLGLFINHYPNGVVTVNCARVIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFLEA--EDDLSSFRAAAITSDLLESLGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITGGAVF--ETMEGNTIEIGCEGD-SISI-----NGIKMVNKKDIVTKNGVIHLIDEVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASS----LKPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLSDLYNGQILET---IGGKQLRVFVY 464          

HSP 2 Score: 51.6026 bits (122), Expect = 4.353e-6
Identity = 63/263 (23.95%), Postives = 118/263 (44.87%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQS-ELREMLDQESDGQWLTVFAPSNTAWEAAKSK-----YGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKE------DLVSGNGVVQIIDSVLVPTSAMSAKD 1284
            YT+LAP    +SDD + + +  L  +      +  HI K ++  +   NG   +T+    +L+V  Y    + I+   +V    + +NG IH     I P        K++   ++ D   + F + +++ +L+++L Q  D  W T+FAP+N A++   S+      G K +L  +N IL  +     I K      P + N    +  ++  S+  L    N+  ++ E      D+++ NGV+ ++D +L P       D
Sbjct:  405 YTLLAPVNNAFSDDTLSMDQRLLKLI------LQNHILKVKVGLSDLYNGQILETIGG-KQLRVFVYRTA-ICIENSCMVRGSKQGRNGAIHIFREIIQP------AEKSLHDKLRQDKRFSIFLSLLEAADLKDLLTQPGD--W-TLFAPTNDAFKGMTSEERELLIGDKNAL--QNIILYHLTPGVYIGK---GFEPGVTN----ILKTTQGSKIYLKGV-NETLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGND 640          
BLAST of Periostin vs. Ensembl Mouse
Match: Postn (periostin, osteoblast specific factor [Source:MGI Symbol;Acc:MGI:1926321])

HSP 1 Score: 110.538 bits (275), Expect = 2.070e-24
Identity = 124/469 (26.44%), Postives = 213/469 (45.42%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYS------DDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARII-KEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F +C   ++   C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   + +S +  L EE  G+ +YT  AP +      D  ++ G  +  NV    + +  H+   RM +    +G    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    L+A   D L++     I S+L E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C++AIT  A     ++    + + C  D S SI     N  +++ K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + S    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   44 NVCA-LQQILGTKKKYFSSCKNWYQGAICGKKTTVLYECCPGYMR-------MEGMKGCPAVMPIDHVYGTLGIVGATTTQHYSDVSKLREEIEGKGSYTYFAPSNEAWENLDSDIRRGLENNVNVE-LLNALHSHMVNKRMLTKDLKHGMVIPSMYNNLGLFINHYPNGVVTVNCARVIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFLEA--EDDLSSFRAAAITSDLLESLGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITGGAVF--ETMEGNTIEIGCEGD-SISI-----NGIKMVNKKDIVTKNGVIHLIDEVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASS----LKPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLSDLYNGQILET---IGGKQLRVFVY 464          

HSP 2 Score: 51.2174 bits (121), Expect = 5.022e-6
Identity = 63/263 (23.95%), Postives = 118/263 (44.87%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQS-ELREMLDQESDGQWLTVFAPSNTAWEAAKSK-----YGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKE------DLVSGNGVVQIIDSVLVPTSAMSAKD 1284
            YT+LAP    +SDD + + +  L  +      +  HI K ++  +   NG   +T+    +L+V  Y    + I+   +V    + +NG IH     I P        K++   ++ D   + F + +++ +L+++L Q  D  W T+FAP+N A++   S+      G K +L  +N IL  +     I K      P + N    +  ++  S+  L    N+  ++ E      D+++ NGV+ ++D +L P       D
Sbjct:  405 YTLLAPVNNAFSDDTLSMDQRLLKLI------LQNHILKVKVGLSDLYNGQILETIGG-KQLRVFVYRTA-ICIENSCMVRGSKQGRNGAIHIFREIIQP------AEKSLHDKLRQDKRFSIFLSLLEAADLKDLLTQPGD--W-TLFAPTNDAFKGMTSEERELLIGDKNAL--QNIILYHLTPGVYIGK---GFEPGVTN----ILKTTQGSKIYLKGV-NETLLVNELKSKESDIMTTNGVIHVVDKLLYPADIPVGND 640          
BLAST of Periostin vs. Ensembl Mouse
Match: Tgfbi (transforming growth factor, beta induced [Source:MGI Symbol;Acc:MGI:99959])

HSP 1 Score: 108.997 bits (271), Expect = 4.740e-24
Identity = 136/583 (23.33%), Postives = 241/583 (41.34%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSE---VESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAP----YSDDAMKLGEFDLSNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKI-------SLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQ--HSRSCDLKINSFSKYILLIPTN----EAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEW-----GSSELNRLFQLH 1926
            N+CA  K   G     F  C   +++  C   T   Y+CCPG+ K P  +  C     + ++++ + V +   +   +    EK        E  G  ++T+ AP    +S    ++ +  +SNV     + +  H+   R+ +++  +G T  ++  +  +++  Y NG+V ++C  L+  DH A NGV+H I   I+  + +  Q+   ++    D           S L  +L  E DGQ+ T+ AP+N A+E   ++  ++I         L+ NHIL   +CA+AI    +    +L    L V CS DK          KA I  +D+++ NGV+  ID +L+P SA +  +          +SDVS+ +        D  ++   +   L P N    +    +  Q K                 +L  H++K +  +    +  + D+    GGK L V  Y       S    N+      +  +F  G +F +DR+  PP  T+M +L       +    +Q  G    +   G   +F A  N  +Q    +E       + EL  + + H
Sbjct:   47 NVCAVQK-VIGTNKKYFTNCKQWYQRKICGKSTVISYECCPGYEKVP-GEKGCPAALPLSNLYETMGV-VGSTTTQLYTDRTEKLRP-----EMEGPGSFTIFAPSNEAWSSLPAEVLDSLVSNVNIELLNALRYHMVDRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVIST-ITNNIQQIIEIE----DTFETLRAAVAASGLNTVL--EGDGQF-TLLAPTNEAFEKIPAETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGMSM--ETLGGTTLEVGCSGDKL-----TINGKAVISNKDILATNGVIHFIDELLIPDSAKTLLELA-------GESDVSTAIDILKQAGLDTHLSGKEQLTFLAPLNSVFKDGVPRIDAQMK----------------TLLLNHMVKEQLASKYLYSGQTLDT---LGGKKLRVFVY-----RNSLCIENSCIAAHDKRGRF--GTLFTMDRMLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLMEILNREGVYTVF-APTNEAFQAMPPEELNKLLANAKELTNILKYH 572          

HSP 2 Score: 64.3142 bits (155), Expect = 3.991e-10
Identity = 94/388 (24.23%), Postives = 158/388 (40.72%), Query Frame = 1
Query:  892 TNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKY------GSKISLL--VKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTS-----AMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPS-KTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWGSSELNRLFQLHTIKMELWGSDMGYFYP-ETLSTLNSAYLE 2010
            T   Y D   +LR   + E  G + T+FAPSN AW +  ++          I LL  ++ H+++R +    + K   +L     N  + +    +   ++     N AR++K D  + NGVV +ID V+   +      +  +D    L    + S +++ L+             ++ LL PTNEA   +  ++         +        +L  H+LK      A V  MS ++    GG  L V         G KL  N       +      G+I F+D + IP S KT+++L  E  DV    + L+  G D+ + S    + FLA  N  ++    +    +++  L   H +K +L      Y Y  +TL TL    L 
Sbjct:  117 TTQLYTDRTEKLRP--EMEGPGSF-TIFAPSNEAWSSLPAEVLDSLVSNVNIELLNALRYHMVDRRVLTDEL-KHGMTLTSMYQNSNIQIHHYPNGIVTV-----NCARLLKADHHATNGVVHLIDKVISTITNNIQQIIEIEDTFETLRAAVAASGLNTVLEGD----------GQFTLLAPTNEAFEKIPAETLNRILGDPEALR-----DLLNNHILKSAMCAEAIVAGMSMETL---GGTTLEV------GCSGDKLTINGKAVISNKDILATNGVIHFIDELLIPDSAKTLLELAGES-DVSTAIDILKQAGLDTHL-SGKEQLTFLAPLNSVFKDGVPRI--DAQMKTLLLNHMVKEQLASK---YLYSGQTLDTLGGKKLR 464          

HSP 3 Score: 53.1434 bits (126), Expect = 1.336e-6
Identity = 61/221 (27.60%), Postives = 103/221 (46.61%), Query Frame = 1
Query:  637 HIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSE-LREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSK-------ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMS 1275
            H+ K ++ S    +G T  TL    KL+V  Y N L  I+   +   D   + G +  +   +TP +G      TV+  ++ D   +     IQS  L E+L++E      TVFAP+N A++A   +  +K       ++ ++K HI + ++ +  I   A     SL  + L V  S +   S+     NK  + + D+++ NGVV  I++VL P    S
Sbjct:  438 HMVKEQLASKYLYSGQTLDTLGGK-KLRVFVYRNSLC-IENSCIAAHDKRGRFGTLFTMDRMLTPPMG------TVMDVLKGDNRFSMLVAAIQSAGLMEILNREG---VYTVFAPTNEAFQAMPPEELNKLLANAKELTNILKYHIGDEILVSGGI--GALVRLKSLQGDKLEVS-SKNNVVSV-----NKEPVAETDIMATNGVVYAINTVLQPPGCFS 639          
BLAST of Periostin vs. UniProt/SwissProt
Match: sp|Q95215|BGH3_RABIT (Transforming growth factor-beta-induced protein ig-h3 OS=Oryctolagus cuniculus OX=9986 GN=TGFBI PE=2 SV=2)

HSP 1 Score: 112.079 bits (279), Expect = 4.092e-24
Identity = 132/514 (25.68%), Postives = 226/514 (43.97%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSE---VESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDL----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKI-------SLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTG-DSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLL 1749
            N+CA  K       Y F  C   +++  C   T   Y+CCPG+ K P  +  C     + ++++ + V +   +   +    EK   ++   E  GR  +T+ AP ++    L    L    SNV     + +  H+   R+ +++  +G    ++  + K ++  Y NG+V ++C  L+  DH A NGV+H I   I+  V +  Q+   ++    D           S L  +L  ESDGQ+ T+ AP+N A E   ++  ++I         L+ NHIL   +CA+AI    +    +L    L V CS D     +     KA I  +D+++ NGV+  ID +L+P SA +    +S L+ G D  + +  F Q      L  N   +  LL P N   +  +E +            + +   +LR H++K +  +    +  + D+    GGK L V  Y       S    N+      +  ++  G +F +DR+  PPS T+M +L
Sbjct:   47 NVCAVQKVIGTNRKY-FTNCKQWYQRKICGKSTVISYECCPGYEKVP-GERSCPAALPLANLYETLGV-VGSTTTQLYTDRTEK---LRPEMEGPGR--FTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVDRRVLTDELKHGMALTSMYQNSKFQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVIST-VTNNIQQIIEIE----DTFETLRAAVAASGLNTLL--ESDGQF-TLLAPTNEAKEKIPTETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSM--ETLEATTLEVGCSGD-----MLTINGKAIISNKDVLATNGVIHFIDELLIPDSAKT----LSELAAGSDVSTAIDLFGQAGLGTHLSGN--ERLTLLAPLN---SVFEEGAP---------PIDAHTRNLLRNHIIKDQLASKYLYHGQTLDT---LGGKKLRVFVY-----RNSLCIENSCIAAHDKRGRY--GTLFTMDRMLTPPSGTVMDVL 509          
BLAST of Periostin vs. UniProt/SwissProt
Match: sp|Q15582|BGH3_HUMAN (Transforming growth factor-beta-induced protein ig-h3 OS=Homo sapiens OX=9606 GN=TGFBI PE=1 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 5.417e-24
Identity = 138/589 (23.43%), Postives = 243/589 (41.26%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSE---VESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDL----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKI-------SLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDL--KINSFSKYILLIPTN----------EAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWG-----SSELNRLFQLH 1926
            N+CA  K       Y F  C   +++  C   T   Y+CCPG+ K P  +  C     + ++++ + V +   +   +    EK        E  G  ++T+ AP ++    L    L    SNV     + +  H+   R+ +++  +G T  ++  +  +++  Y NG+V ++C  L+  DH A NGV+H I   I+  + +  Q+   ++    D           S L  ML  E +GQ+ T+ AP+N A+E   S+  ++I         L+ NHIL   +CA+AI    +    +L    L V CS D     +     KA I  +D+++ NGV+  ID +L+P SA +  +         ++SDVS+ +   R   L   ++   +  LL P N          +AHT                        +LR H++K +  +    +  + ++    GGK L V  Y       S    N+      +  ++  G +F +DR+  PP  T+M +L       +    +Q  G    +   G   +F A  N  ++    +E       + EL  + + H
Sbjct:   47 NVCAVQKVIGTNRKY-FTNCKQWYQRKICGKSTVISYECCPGYEKVP-GEKGCPAALPLSNLYETLGV-VGSTTTQLYTDRTEKLRP-----EMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVIST-ITNNIQQIIEIE----DTFETLRAAVAASGLNTML--EGNGQY-TLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSV--ETLEGTTLEVGCSGD-----MLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELA-------AESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTPPIDAHTR----------------------NLLRNHIIKDQLASKYLYHGQTLET---LGGKKLRVFVY-----RNSLCIENSCIAAHDKRGRY--GTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVF-APTNEAFRALPPRERSRLLGDAKELANILKYH 572          

HSP 2 Score: 56.6102 bits (135), Expect = 8.514e-7
Identity = 59/223 (26.46%), Postives = 100/223 (44.84%), Query Frame = 1
Query:  637 HIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSE-LREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSK-------ISLLVKNHILNRMICAQAI-------TKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVP 1260
            HI K+++ S    +G T +TL    KL+V  Y N L  I+   +   D   + G +  +   +TP +G      TV+  ++ D   +     IQS  L E L++E      TVFAP+N A+ A   +  S+       ++ ++K HI + ++ +  I       + +   L  SL N  + V               NK  + + D+++ NGVV +I +VL P
Sbjct:  438 HIIKDQLASKYLYHGQTLETLGGK-KLRVFVYRNSLC-IENSCIAAHDKRGRYGTLFTMDRVLTPPMG------TVMDVLKGDNRFSMLVAAIQSAGLTETLNREG---VYTVFAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSV---------------NKEPVAEPDIMATNGVVHVITNVLQP 634          
BLAST of Periostin vs. UniProt/SwissProt
Match: sp|Q62009|POSTN_MOUSE (Periostin OS=Mus musculus OX=10090 GN=Postn PE=1 SV=2)

HSP 1 Score: 110.923 bits (276), Expect = 1.226e-23
Identity = 124/469 (26.44%), Postives = 213/469 (45.42%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYS------DDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARII-KEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F +C   ++   C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   + +S +  L EE  G+ +YT  AP +      D  ++ G  +  NV    + +  H+   RM +    +G    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    L+A   D L++     I S+L E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C++AIT  A     ++    + + C  D S SI     N  +++ K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + S    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   44 NVCA-LQQILGTKKKYFSSCKNWYQGAICGKKTTVLYECCPGYMR-------MEGMKGCPAVMPIDHVYGTLGIVGATTTQHYSDVSKLREEIEGKGSYTYFAPSNEAWENLDSDIRRGLENNVNVE-LLNALHSHMVNKRMLTKDLKHGMVIPSMYNNLGLFINHYPNGVVTVNCARVIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFLEA--EDDLSSFRAAAITSDLLESLGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSEAITGGAVF--ETMEGNTIEIGCEGD-SISI-----NGIKMVNKKDIVTKNGVIHLIDEVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASS----LKPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLSDLYNGQILET---IGGKQLRVFVY 464          
BLAST of Periostin vs. UniProt/SwissProt
Match: sp|Q15063|POSTN_HUMAN (Periostin OS=Homo sapiens OX=9606 GN=POSTN PE=1 SV=2)

HSP 1 Score: 109.383 bits (272), Expect = 3.555e-23
Identity = 120/468 (25.64%), Postives = 210/468 (44.87%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPV-HLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYS------DDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWE-----AAKSKYGSKIS--LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEA---HTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTY 1605
            N+CA L+   G     F TC   +K++ C  +TT  Y+CCPG+ +          ++    ++P+ H+        A   +++S    L EE  G+ ++T  AP +      D  ++ G     NV    + +  H+   RM +    NG    ++ ++  L +  Y NG+V ++C  +++ +  A NGV+H I   +T  +G+  Q    ++A   D L++     I S++ E L +  DG + T+FAP+N A+E       +   G K++   L+K HILN + C+++I   A     +L    + + C  D     +   G K  + K+D+V+ NGV+ +ID VL+P SA    +      T  + +D+ + L  + +    +    +Y LL P N A    T   +Q                   +L+ H+LK+K       N    ++    GGK L V  Y
Sbjct:   42 NVCA-LQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMR-------MEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVE-LLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLT-QIGTSIQ--DFIEA--EDDLSSFRAAAITSDILEALGR--DGHF-TLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVF--ETLEGNTIEIGCDGDS----ITVNGIKM-VNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQT--TFTDLVAQLGLASA----LRPDGEYTLLAPVNNAFSDDTLSMDQRLLKL--------------ILQNHILKVKVGLNELYNGQILET---IGGKQLRVFVY 462          

HSP 2 Score: 53.9138 bits (128), Expect = 5.423e-6
Identity = 60/257 (23.35%), Postives = 114/257 (44.36%), Query Frame = 1
Query:  544 YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQS-ELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLG--PSLANEYLGVDCSSDKSRSILDAC-GNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAV 1290
            YT+LAP    +SDD + + +  L  +      +  HI K ++  N+  NG   +T+    +L+V  Y    V I+   +     + +NG IH     I P        K++ + ++ D   ++F + +++ +L+E+L Q  D  W T+F P+N A++   S+   K  L+   + L  +I            G  P + N       S    + + D    N+ +  + D+++ NGV+ ++D +L P       D +
Sbjct:  403 YTLLAPVNNAFSDDTLSMDQRLLKLI------LQNHILKVKVGLNELYNGQILETIGG-KQLRVFVYRTA-VCIENSCMEKGSKQGRNGAIHIFREIIKP------AEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGD--W-TLFVPTNDAFKGMTSE--EKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQL 640          
BLAST of Periostin vs. UniProt/SwissProt
Match: sp|P82198|BGH3_MOUSE (Transforming growth factor-beta-induced protein ig-h3 OS=Mus musculus OX=10090 GN=Tgfbi PE=1 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 4.062e-23
Identity = 136/583 (23.33%), Postives = 241/583 (41.34%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSE---VESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAP----YSDDAMKLGEFDLSNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKI-------SLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQ--HSRSCDLKINSFSKYILLIPTN----EAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEW-----GSSELNRLFQLH 1926
            N+CA  K   G     F  C   +++  C   T   Y+CCPG+ K P  +  C     + ++++ + V +   +   +    EK        E  G  ++T+ AP    +S    ++ +  +SNV     + +  H+   R+ +++  +G T  ++  +  +++  Y NG+V ++C  L+  DH A NGV+H I   I+  + +  Q+   ++    D           S L  +L  E DGQ+ T+ AP+N A+E   ++  ++I         L+ NHIL   +CA+AI    +    +L    L V CS DK          KA I  +D+++ NGV+  ID +L+P SA +  +          +SDVS+ +        D  ++   +   L P N    +    +  Q K                 +L  H++K +  +    +  + D+    GGK L V  Y       S    N+      +  +F  G +F +DR+  PP  T+M +L       +    +Q  G    +   G   +F A  N  +Q    +E       + EL  + + H
Sbjct:   47 NVCAVQK-VIGTNKKYFTNCKQWYQRKICGKSTVISYECCPGYEKVP-GEKGCPAALPLSNLYETMGV-VGSTTTQLYTDRTEKLRP-----EMEGPGSFTIFAPSNEAWSSLPAEVLDSLVSNVNIELLNALRYHMVDRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVIST-ITNNIQQIIEIE----DTFETLRAAVAASGLNTVL--EGDGQF-TLLAPTNEAFEKIPAETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGMSM--ETLGGTTLEVGCSGDKL-----TINGKAVISNKDILATNGVIHFIDELLIPDSAKTLLELA-------GESDVSTAIDILKQAGLDTHLSGKEQLTFLAPLNSVFKDGVPRIDAQMK----------------TLLLNHMVKEQLASKYLYSGQTLDT---LGGKKLRVFVY-----RNSLCIENSCIAAHDKRGRF--GTLFTMDRMLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLMEILNREGVYTVF-APTNEAFQAMPPEELNKLLANAKELTNILKYH 572          

HSP 2 Score: 63.929 bits (154), Expect = 4.535e-9
Identity = 94/387 (24.29%), Postives = 158/387 (40.83%), Query Frame = 1
Query:  892 TNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKY------GSKISLL--VKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTS-----AMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPS-KTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWGSSELNRLFQLHTIKMELWGSDMGYFYP-ETLSTLNSAYL 2007
            T   Y D   +LR   + E  G + T+FAPSN AW +  ++          I LL  ++ H+++R +    + K   +L     N  + +    +   ++     N AR++K D  + NGVV +ID V+   +      +  +D    L    + S +++ L+             ++ LL PTNEA   +  ++         +        +L  H+LK      A V  MS ++    GG  L V         G KL  N       +      G+I F+D + IP S KT+++L  E  DV    + L+  G D+ + S    + FLA  N  ++    +    +++  L   H +K +L      Y Y  +TL TL    L
Sbjct:  117 TTQLYTDRTEKLRP--EMEGPGSF-TIFAPSNEAWSSLPAEVLDSLVSNVNIELLNALRYHMVDRRVLTDEL-KHGMTLTSMYQNSNIQIHHYPNGIVTV-----NCARLLKADHHATNGVVHLIDKVISTITNNIQQIIEIEDTFETLRAAVAASGLNTVLEGD----------GQFTLLAPTNEAFEKIPAETLNRILGDPEALR-----DLLNNHILKSAMCAEAIVAGMSMETL---GGTTLEVGC------SGDKLTINGKAVISNKDILATNGVIHFIDELLIPDSAKTLLELAGES-DVSTAIDILKQAGLDTHL-SGKEQLTFLAPLNSVFKDGVPRI--DAQMKTLLLNHMVKEQLASK---YLYSGQTLDTLGGKKL 463          
BLAST of Periostin vs. TrEMBL
Match: A0A4E0RIM6 (Gynecophoral canal protein OS=Fasciola hepatica OX=6192 GN=D915_001851 PE=4 SV=1)

HSP 1 Score: 387.497 bits (994), Expect = 1.993e-120
Identity = 211/617 (34.20%), Postives = 349/617 (56.56%), Query Frame = 1
Query:  358 FEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKY--GSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTP---------AFVNQMSFDSNLDN-GGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRK-EKEWGSSELNRLFQLHTIKMELWGSDMGYFYPETLSTLNSAYLE-SGNPFQLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWIIDWPLK 2166
            +EY CCPG+ +S L++N+C ++E+ WK I  +LK+    + A  L  ++++ DL ++  +  YTV  P  D  ++  E D  + G     +   + + R YS+ F NG       ++  LK TTYSNGL+F++C   ++ DHE  NG++HY    I P      +  TVL  +Q+D   + F   +  ++R +LDQ +   W TVFAP+N AW  A S+   G  ++ L ++H+L +M+C++AIT+ ++ +GP++A +Y+ +  +++   ++L  C ++    + DL+S  GV+ +ID  + P  +M   +A+ CL  G  K +++   +    CD+   S +K +LL PT +A   LQ      +   +M S+  Y+C+V  +H+L    D P          FV +  F ++     G P+ V   +V++RDGSKL FN A+TT L+P KF  G+I+ V+ +N PP KTM++L+ E P+      K+Q+TG           VLFLA  + GW+TR  E  + + +  +L QLHTI   ++G D G+ +  T+  ++S   + SG   QL IKR  +GN FIG+  LP +LW++V++ N  GTDG++W+IDWP+K
Sbjct:   90 YEYDCCPGYERSTLLNNKCVQMEATWKPIVRYLKERGNVETASALANNTRLPDLSQDPAKYVYTVFVPKEDGDIRSPEIDYRSGGNSARNL---VTRGRHYSHGFTNGRKIPN-ENNFPLKFTTYSNGLIFVECALFLSVDHETTNGLVHYTDRAIPP----SNRYPTVLSRLQSDSDLSQFVQALPPDVRSVLDQRNSNTWYTVFAPTNRAWNEAVSRLPPGESVANLARHHVLKKMLCSRAITRDSSEVGPTMAEDYVRMTRTTNGRPAVLGPCSDQIPFERPDLMSATGVIHVIDKAITPLGSMELDEALKCLQRG-GKQELAQAAREMEECDVVSRSKAKVVLL-PTAKA---LQGAGDNPSMAKRMRSDRAYRCKVYAHHLLT--PDNPKSLKNTKQNGFVQEEKFRTDYTAPNGSPVFVTGSYVRERDGSKLSFNGAKTTNLKPLKFRNGLIYSVESVNYPPEKTMLELIREEPNTTQIVSKIQETGIQKDFDRLESKVLFLAPIDMGWKTRDVENAYSTPQTRKLLQLHTIPHPIFGGDNGFVWHSTIHKVDSLLPDRSGGRIQLTIKRHPDGNTFIGHSELPEKLWAMVLKWNKVGTDGVVWMIDWPIK 691          
BLAST of Periostin vs. TrEMBL
Match: A0A4S2LDH2 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_008075 PE=4 SV=1)

HSP 1 Score: 382.489 bits (981), Expect = 1.141e-118
Identity = 220/687 (32.02%), Postives = 373/687 (54.29%), Query Frame = 1
Query:  136 MFAGFYILSVLLIVVNAQVNPKYPRYTPVAKELAQPFKETNLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYG--SKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVL-----KMKGDTPAFVNQMSFDSNLDN-GGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRK-EKEWGSSELNRLFQLHTIKMELWGSDMGYFYPETLSTLNSAYLESGNPF-QLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWIIDWPLK 2166
            +F     L+ LL  V +   P  PR      + AQ     N+C ++      LP   W C  P        +  + Y CCPG++KS ++ NQC + +S WK +  +L+D      A+ L++++ I+DL  E  +  YTV  P +D+ +K  E D +   G  +     + + R YS  F+NGA      +   LK+T+YS+GL F++CR L++ DHE  NG+IHY  G + P  G   +  TV++ +Q++P  ++F   +  + +  L +    +  TVFAP+N+AW+ A    G    ++ L  +H+LN+MIC+ AI +++  +GP+ A++Y+ +  +SD + ++LDAC  +   +K+DL+S  GVV +I+ V      +S  +A++C++ G  +  +S   +  + CDL  N  +  ++LIP  EA  WL  +     E  +M S+  YKCQV  +H+L     K   +   F  +  F+++     G+   V ++++  RDG +L FNAA+T   +P  F  G+I+ V +IN PP K M+Q++   P++    EK++ TG        G   LFLA  + GW+TR  E  +   +  +L QLHTI   L+G + G+    ++ T+++   E G  + +L IK + +GN  IG+  +  +LW++V++ N  GTDG++W+IDWP+K
Sbjct:    2 LFRTAVFLAGLLGTVLSNDRPPDPRNFQTF-DTAQKRSGENMCPYIIKGSKKLPVICWMCHFPHGM---RPDNRYVYDCCPGYSKSDIIPNQCVQRDSTWKDLIRYLEDNGNSNTARALKENTAIQDLQAEPSQKVYTVFVPQNDEDIKNAELDYT---GRDNSARNLVAQGRHYSPSFINGAKIPN-ENSVDLKITSYSSGLTFVECRMLMSADHETTNGLIHYTDGAL-PATG---KYSTVMERLQDEPDISNFVQALPPDTKYALSRRDSRELYTVFAPTNSAWKDALKGLGPGESVASLANHHVLNKMICSGAIIQESGDVGPTQADDYIKLTLTSDGNPAVLDACNQQIPFVKKDLMSKTGVVHVIERVATSLLPLSLSEAINCIAEG-PQHKLSQSAREIKDCDLVTNPKAN-VILIPDEEAFKWLTSKRNQLEEAKRMLSDRRYKCQVYAHHMLTDKMMKQPSNFNGFGQEYRFETDYRAPSGEHPPVFSHYITGRDGRRLSFNAAQTKNRKPVIFRDGVIYPVQKINFPPDKNMVQVIENEPNMTRVAEKIKSTGMQQEFVKMGGKTLFLAPIDMGWKTRDLENGYTIDQTRKLLQLHTIPHALFGGEDGFLRRASVQTVDTLLPERGGGYVKLTIKYQPDGNALIGHPEISEDLWAMVLKWNKVGTDGVVWVIDWPIK 674          
BLAST of Periostin vs. TrEMBL
Match: A0A4S2LCW8 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_008075 PE=4 SV=1)

HSP 1 Score: 380.563 bits (976), Expect = 5.268e-118
Identity = 219/687 (31.88%), Postives = 373/687 (54.29%), Query Frame = 1
Query:  136 MFAGFYILSVLLIVVNAQVNPKYPRYTPVAKELAQPFKETNLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYG--SKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVL-----KMKGDTPAFVNQMSFDSNLDN-GGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRK-EKEWGSSELNRLFQLHTIKMELWGSDMGYFYPETLSTLNSAYLESGNPF-QLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWIIDWPLK 2166
            +F     L+ LL  V +   P  PR      + AQ     N+C ++      LP   W C  P        +  + Y CCPG++KS ++ NQC + +S WK +  +L+D      A+ L++++ I+DL  E  +  YTV  P +D+ +K  E D +   G  +     + + R YS  F+NGA      +   LK+T+YS+GL F++CR L++ DHE  NG+IHY  G + P  G   +  TV++ +Q++P  ++F   +  + +  L +    +  TVFAP+N+AW+ A    G    ++ L  +H+LN+MIC+ AI +++  +GP+ A++Y+ +  +SD + ++LDAC  +   +K+DL+S  GVV +I+ V      +S  +A++C++ G  +  +S   +  + CDL  N  +  ++LIP  EA  WL  +     E  +M S+  YKCQV  +H+L     K   +   F  +  F+++     G+   V ++++  RDG +L FNAA+T   +P  F  G+I+ V +IN PP K ++Q++   P++    EK++ TG        G   LFLA  + GW+TR  E  +   +  +L QLHTI   L+G + G+    ++ T+++   E G  + +L IK + +GN  IG+  +  +LW++V++ N  GTDG++W+IDWP+K
Sbjct:    2 LFRTAVFLAGLLGTVLSNDRPPDPRNFQTF-DTAQKRSGENMCPYIIKGSKKLPVICWMCHFPHGM---RPDNRYVYDCCPGYSKSDIIPNQCVQRDSTWKDLIRYLEDNGNSNTARALKENTAIQDLQAEPSQKVYTVFVPQNDEDIKNAELDYT---GRDNSARNLVAQGRHYSPSFINGAKIPN-ENSVDLKITSYSSGLTFVECRMLMSADHETTNGLIHYTDGAL-PATG---KYSTVMERLQDEPDISNFVQALPPDTKYALSRRDSRELYTVFAPTNSAWKDALKGLGPGESVASLANHHVLNKMICSGAIIQESGDVGPTQADDYIKLTLTSDGNPAVLDACNQQIPFVKKDLMSKTGVVHVIERVATSLLPLSLSEAINCIAEG-PQHKLSQSAREIKDCDLVTNPKAN-VILIPDEEAFKWLTSKRNQLEEAKRMLSDRRYKCQVYAHHMLTDKMMKQPSNFNGFGQEYRFETDYRAPSGEHPPVFSHYITGRDGRRLSFNAAQTKNRKPVIFRDGVIYPVQKINFPPDKNLVQVIENEPNMTRVAEKIKSTGMQQEFVKMGGKTLFLAPIDMGWKTRDLENGYTIDQTRKLLQLHTIPHALFGGEDGFLRRASVQTVDTLLPERGGGYVKLTIKYQPDGNALIGHPEISEDLWAMVLKWNKVGTDGVVWVIDWPIK 674          
BLAST of Periostin vs. TrEMBL
Match: A0A0R3SA45 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS1196 PE=4 SV=2)

HSP 1 Score: 378.252 bits (970), Expect = 2.517e-117
Identity = 237/674 (35.16%), Postives = 363/674 (53.86%), Query Frame = 1
Query:  196 PKYP-RYTPVAKELAQPFKETNLCAFLK-PSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMK-LGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSK--ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVL-----KMKG----DTPA---FVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTR-KEKEWGSSELNRLFQLHTIKMELWGSDMGYFYPETLSTLNSAYLESGNPFQLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWIIDWPL 2163
            P+ P +Y P  K     FKE N+CA+    + G    S W CG P  + Y     T  Y CCPG+ +S +V+N+C E    +  I   L+D    + A +L+   Q++   ++NG+D +TV  P  D +++ + E D  N+          I   R YS  F +G    T +  + LK+TTY+NGLVF++C+ L  PD E  NG+IH ISGPI   V   Y+  +V+  +++DP  +SF  DI S+LR  L   +  +  TVFAP+NTAW AAK + G    ++ LV+ H+ + +IC Q+I  +   LGPS AN Y+  +   D  R + D+CG +A   + D+++GNGVV  +   L   ++M+ K A++CL+ G  K D++   +   SC + I S    ++L+PT EA                +  +    C + + HVL     KMK      TP    + +Q +       GG+  +    +++ RDGS L+F  A TT L+P  F +G+IF V  IN PP++TMM+++ E PD+  T EK+Q  G+ + +     NV+F A QNHGW+TR KE  +G  +L  LF++ TI  +L     G    ET+  + S    SG    L+IKR L+GN FIGY+G+  +LW+L I   +  +DG++ ++DWPL
Sbjct:   31 PELPQKYNP--KNYKPLFKEINMCAYKNVKTDGGGNISAWICG-PVDEQY----GTVTYDCCPGYKRSSIVNNECVERNPTYMSIISTLQDMKKDETADILQ---QLEPALDKNGKD-FTVFVPEEDSSLQFIKELDAVNL----------IVPGRYYSGDFKSGTDIPTKTG-YPLKITTYNNGLVFVECQLLTKPDFETSNGIIHIISGPI--DVSKNYE--SVMDRLRSDPDLSSFTADIPSDLRAQLSASNSRERYTVFAPTNTAWTAAKREIGDSQGVTDLVRQHVQDSLICGQSIDNQNRLLGPSKANTYVYANQQHDGMRFLEDSCGGRAHFAQMDMMAGNGVVHKLSRALQSPTSMNLKGALNCLANGPDK-DLNQAAREMVSCGIDIRSGDNAVVLLPTTEA----------------LRKSLTSGCNLYQNHVLTSTDCKMKNVYGIGTPQECLYTSQYTAP-----GGRHPTFTNQYIRSRDGSTLHFGKAETTSLKPIPFREGVIFTVKSINPPPTRTMMEIVRENPDLSTTYEKMQRAGFPTILSQKSPNVVFFAPQNHGWKTRDKENAYGPGQLRNLFEMQTIPHQLITGKDGNVDSETIQEMQSI---SG--VYLKIKRTLDGNTFIGYDGMHPDLWALAIGDPIVASDGIVQVVDWPL 651          
BLAST of Periostin vs. TrEMBL
Match: A0A074YWU2 (Fasciclin domain protein OS=Opisthorchis viverrini OX=6198 GN=T265_11903 PE=4 SV=1)

HSP 1 Score: 365.925 bits (938), Expect = 2.717e-112
Identity = 215/681 (31.57%), Postives = 365/681 (53.60%), Query Frame = 1
Query:  157 LSVLLIVVNAQVNPKYPRYTPVAKELAQPFKETNLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYG--SKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVL-----KMKGDTPAFVNQMSFDSN--LDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRK-EKEWGSSELNRLFQLHTIKMELWGSDMGYFYPETLSTLNSAYLESGNPF-QLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWIIDWPLK 2166
            L+ LL  V +   P  PR      + AQ     N+C ++      LP   W C  P        +T + Y CCPG++KS ++ NQC + +  WK +   L+D      A+ L++++ I+DL  +  +  YTV  P +D+ +K  E D +   G  +     + + R YS  FVNGA      +   LK+T+YS GL F++CR L++ DHE  NG+IHY  G + P  G   +  +V+  +Q +P  ++F   +  + +  L +    +  TVFAP+N AW  A  + G  + ++ L  +H+LN+MIC+ AI +++  +GP+ A +Y+ +  +SD + ++LDAC  +   +K+DL+S  GVV II+ V      +S  +A++C++ G     + S  +  + CD+  N+ +  ++L+P  EA  WL  +     E  +M ++ +YKCQV  +H+L     K       F  +  F+++    NG  P  V +++V  RDG +L FNAA+T   +P  F  G+I+ V ++N PP + M+ ++   P++    EK++ TG            LFLA  + GW+TR  E  +   +  +L QLHTI   L+G + G+    ++ T+++   E G  + +L IK + +GN  IG+  +  +LW++V++ N  GTDG++W+IDWP+K
Sbjct:    9 LAGLLGTVLSNDRPPDPRNFQTF-DTAQKRAGENMCPYIVKGSKKLPVICWMCHFPHG---LRPDTRYVYDCCPGYSKSDIIPNQCVQRDPTWKDLLTFLEDNGNSNTARALKENTAIQDLQAKPSQKVYTVFVPQNDEDIKNAELDYT---GRDNSARTLVAQGRHYSPSFVNGAKIPN-ENAVDLKITSYSTGLTFVECRMLMSTDHETTNGLIHYTDGAL-PATG---KYPSVMDRLQAEPDISNFVQALPPDTKNALSRRDSRELYTVFAPTNDAWNDAVKRLGPGASVASLANHHVLNKMICSGAIIQESNDVGPTQAADYIKLTLTSDGNPAVLDACSQQIPFLKKDLMSKTGVVHIIERVATSLLPLSLNEAINCIAQGPQHKLLQS-AREIKDCDVVKNTKAN-VILMPDEEAFKWLTLKRNQLEEAKRMLADRKYKCQVYAHHMLTDKMMKQPFKFNGFGQEYRFETDYRAPNGEHP-PVFSHYVTGRDGRRLNFNAAQTRNRKPMIFRDGVIYPVQKLNFPPDRNMIHVIENEPNLTKVAEKIKSTGMQQEFAKMEGKTLFLAPIDMGWKTRDLENGYTIDQTRKLLQLHTIPHALFGGEEGFLRRASVQTVDTLLPERGGGYVKLTIKVQPDGNTLIGHPEISEDLWAMVLKWNKVGTDGVVWVIDWPIK 674          
BLAST of Periostin vs. Ensembl Cavefish
Match: postna (periostin [Source:NCBI gene;Acc:103035536])

HSP 1 Score: 120.553 bits (301), Expect = 1.499e-27
Identity = 116/408 (28.43%), Postives = 200/408 (49.02%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDN--QCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYSD-------DAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAW-----EAAKSKYGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKS---DVSSFLQHSRSCDLKINSFSKYILLIPTNEAHT 1419
            N+CA L+   G     F TC   +K T C  +    Y+CCPG+ +   +      S +++V+  + + LK       A + +++S I  + EE +G  TYT+ AP  D        A K  E +++N     + +  H+   R+ +    N    +++ ++  L +  YSNG+V ++C  +++ +  A NGV+H I   I+  VGS    K V+ + +     ++ +N ++S L E LDQ   G + T+FAP++ A+     E  +   G +  L   +K H+LN M C++AI   + S+  +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P SA    + V     G S+S   D+ S L  S +    + + ++Y LL P N   T
Sbjct:   42 NMCA-LQQVMGTKKKYFSTCRNWYKGTICGKKAVVLYECCPGYMELEGMRGCPAASPIDNVYGTLGL-LK-------ADITKRYSDISKIKEEIDGSGTYTMFAPTDDAWDQLDGTARKALEGNVNN--ELYNALHYHMVNKRLVTKDLKNDLKLESMHNNQGLHINHYSNGIVTVNCARIIHANQVATNGVVHLIDRVISA-VGSTI--KEVINSNEELGSLSAAFN-VESTLLEKLDQP--GHY-TLFAPTDNAFDSMDREVIERVLGDQTVLKAFLKYHLLNSMQCSEAIM--SGSVYETLEGSNIEIGCDGDS----LTVNGIKM-VLKKDIVTSNGVIHLIDQVLMPDSAKQVTELV-----GGSQSTFGDMVSELGLSAA----MGAGTQYTLLAPLNGVFT 415          
BLAST of Periostin vs. Ensembl Cavefish
Match: postna (periostin [Source:NCBI gene;Acc:103035536])

HSP 1 Score: 120.168 bits (300), Expect = 1.763e-27
Identity = 116/408 (28.43%), Postives = 200/408 (49.02%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDN--QCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYSD-------DAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAW-----EAAKSKYGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKS---DVSSFLQHSRSCDLKINSFSKYILLIPTNEAHT 1419
            N+CA L+   G     F TC   +K T C  +    Y+CCPG+ +   +      S +++V+  + + LK       A + +++S I  + EE +G  TYT+ AP  D        A K  E +++N     + +  H+   R+ +    N    +++ ++  L +  YSNG+V ++C  +++ +  A NGV+H I   I+  VGS    K V+ + +     ++ +N ++S L E LDQ   G + T+FAP++ A+     E  +   G +  L   +K H+LN M C++AI   + S+  +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P SA    + V     G S+S   D+ S L  S +    + + ++Y LL P N   T
Sbjct:   42 NMCA-LQQVMGTKKKYFSTCRNWYKGTICGKKAVVLYECCPGYMELEGMRGCPAASPIDNVYGTLGL-LK-------ADITKRYSDISKIKEEIDGSGTYTMFAPTDDAWDQLDGTARKALEGNVNN--ELYNALHYHMVNKRLVTKDLKNDLKLESMHNNQGLHINHYSNGIVTVNCARIIHANQVATNGVVHLIDRVISA-VGSTI--KEVINSNEELGSLSAAFN-VESTLLEKLDQP--GHY-TLFAPTDNAFDSMDREVIERVLGDQTVLKAFLKYHLLNSMQCSEAIM--SGSVYETLEGSNIEIGCDGDS----LTVNGIKM-VLKKDIVTSNGVIHLIDQVLMPDSAKQVTELV-----GGSQSTFGDMVSELGLSAA----MGAGTQYTLLAPLNGVFT 415          
BLAST of Periostin vs. Ensembl Cavefish
Match: tgfbi (transforming growth factor beta induced [Source:NCBI gene;Acc:103033053])

HSP 1 Score: 106.686 bits (265), Expect = 2.283e-23
Identity = 129/544 (23.71%), Postives = 224/544 (41.18%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDD--AMKLGEFD--LSNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYIS---GPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAW-----EAAKSKYGSKISL--LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLF 1842
            N+CA  K  QG     F  C   + +  C   TT  Y+CCPG+ K  + +  C     +  I   +          K+  + +++++  E  G  ++T  AP ++   A+     D  +SNV     + +  H+   R+ S+   +G++F ++  D  + +  YSNG+V ++C  LV  D  A NG++H +      IT +V +  + +  LQ++Q             + L  ML  E++G + T+FAP+N A+     E      G  ++L  L+  HI+  + CA++I   A     +L    L V C  +           KA + ++D +  NGVV  I  +LVP SA + K+    L+ G  +   S  L         +       L+ P N+A       +                 + LR H+LK K  + +  +    ++    GG  L V  Y       +    NA      +  ++  G +F VD+I  PP  T+M +L       +  + +Q  G    +   G   +F
Sbjct:   41 NVCAMQK-IQGTDKKYFTNCKQWYHRKICGKPTTIAYECCPGYEKV-VGEKGCPAALPLLNIY--NTLGVVGATTTKMYSERAKLQEEIE--GPGSFTFFAPSNEAWAALPTEILDALVSNVNIELLNALHYHMVNKRLTSDDLKHGSSFPSMYQDFDVHIHHYSNGIVTVNCARLVKTDQHATNGIVHVVDRVITAITNNVNAFLETEDELQSLQTAIAA--------AGLTSML--ENEGSY-TIFAPTNEAFKKIPQEMLDRILGDPVALKDLLNYHIVKNLHCAESIV--AGVPLETLQGTVLEVGCDGNDM-----TLNGKAIVTEKDKLGTNGVVHYISELLVPDSAKTLKE----LAEGTPQVSTSIKLFMDAGLGAHLTGSETVTLIAPQNDAFKGSATLTPSLR-------------KALRNHILKNKFSSKSLYHGQELET---LGGNKLRVFVY-----RNNLCIENACIAAHDKDGRY--GTMFTVDKILAPPMGTVMDVLKADSRFSILVDNVQKAGLTELLNKEGPYTIF 533          
BLAST of Periostin vs. Ensembl Cavefish
Match: postnb (periostin, osteoblast specific factor b [Source:ZFIN;Acc:ZDB-GENE-030131-9120])

HSP 1 Score: 105.531 bits (262), Expect = 5.657e-23
Identity = 135/546 (24.73%), Postives = 230/546 (42.12%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLL--EKHSQIKDLFEE-NGRDTYTVLAPYSDDAMKLGEFDL-----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSK-------ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDN-GGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLF 1842
            N+CA L+   G     F TC   ++   C  + T  Y+CCPG+ K   +   C  V  +  +       Y        +  +++S +  L EE  G  +YT  AP S++A  L + ++     SNV     + +  H+   R+ +    NG T  ++ +D  L +  YSNG+V ++C  +++ +  A NGV+H I   IT  VG+     T+   +  D   +S   +  +    ++D+       T+FAP++ A+         +       +  L+  H+L+ + C++AI    +    +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P SA    + V    +  + SD+ S L  S S   K    ++Y LL P N A +          +          K  +L  HVLK K      + Q+     L+  GGK L V  Y       +    NA        ++ A G +  +     P   +M +LL+E    K+    ++  G    +K  G   LF
Sbjct:   42 NVCA-LQQVMGTKKKYFSTCRNWYQGAICGKKATVLYECCPGYMKLEGMRG-CPAVAPIDNV-------YGTLGLINAITTQEYSSLSKLREEIEGSGSYTFFAP-SNEAWDLLDAEVRNALVSNVNIELYNALHYHMANKRLLTKDLRNGLTVTSMYNDLSLHINHYSNGIVTVNCARIIHGNQVATNGVVHVIDRVITA-VGN-----TIQDVIDVDDELSSL--NTMATAAGLMDKLGQPGHFTLFAPTDDAFSKLDGDVMERLMADKDVLQALINYHLLDSVQCSEAIMSGTSY--ETLEGTNIEIGCDGDS----LTVNGVKM-VLKKDIVTTNGVIHLIDQVLMPDSAKQVMELVG--PSQSTFSDMVSELGLSASMRPK----AEYTLLAPLNSAFS----------DEVMSMDQRLLKI-ILENHVLKSK----IVLGQLYNGQRLETLGGKFLRVFVYRT-----AVCIENACLIRG--SKEGANGALHLMKTFIKPAESSMFKLLTEHGGFKIFLSLMEAAGLTDLLKQEGDFTLF 534          
BLAST of Periostin vs. Ensembl Sea Lamprey
Match: tgfbi (transforming growth factor, beta-induced [Source:ZFIN;Acc:ZDB-GENE-030131-73])

HSP 1 Score: 86.2705 bits (212), Expect = 8.365e-18
Identity = 127/557 (22.80%), Postives = 229/557 (41.11%), Query Frame = 1
Query:  340 CESETTFEYQCCPGFTKSPLVD--NQCSEV---ESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMK-----LGEFDLSNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITP---HVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKI-------SLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDR-INIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWG-----SSELNRLFQLHT 1929
            C S     Y CCPG+ K   VD  N CS +   E+V+  +  +++  S   +  +    S ++   E +G   +TV  P SD+A +     + E  +SNV     + ++ H+   R+ ++   +G    +  ++  L +  +SNG+V ++C  L+ P+  A NGV+H I   I P    +    +    L++++           +  E   M+   S    LT+FAP+N A E    +   +I        ++++ H++  +IC++++  +   L  +     L   C     R  L   G    + + D+V+ NGVV +ID +++P SA    +           S V++F+      DL   S +K  L     E++T L  +     E+      E+ K ++L  HV++ +  +    N    ++     G  L V  Y       S       RT +        G IF +D+ +  PP  T+M +L       +    L+  G+  ++ S   ++   A  N  + T    E       S EL  L   H 
Sbjct:    2 CISNRVVTYDCCPGYVK---VDGINGCSAITPMENVYNTME-YVEAMSTQSYFNI----SGLRPNVEASG--IHTVFTP-SDEAWEALSEDIREALVSNVNLELRNALSYHMVSRRLLTSDLRDGLVLTSNYENQPLFINHHSNGVVTVNCARLIRPNFLATNGVVHTIDRVIVPVSNRISEIVEFTAELESLK-----------VLMEKAGMMPLLSSEGPLTLFAPTNEAIERVPKETMDRIMGDPKTLKMVLEGHMMRSVICSESLLGEDVVLPTAGGAPALVASCQGSSIR--LRGGG---EVTRRDIVTTNGVVHLIDHLVLPDSARDVLEVA-------EDSGVNTFM------DLLEESGAKAQL--QHEESYTLLTVKDSAVTESFTADRGEKLKQKML-AHVVRGRYLSDRLFNGQRLET---LAGGTLRVFIYHRALCIESSCVDTKDRTAR-------NGAIFILDKPLPPPPRSTLMNMLEADTRFTMLVSLLRTAGFAEKL-SMPVDLTIFAPTNEAFGTLPVAELARLSRNSKELQELLLSHV 504          

HSP 2 Score: 59.6918 bits (143), Expect = 1.578e-9
Identity = 68/278 (24.46%), Postives = 123/278 (44.24%), Query Frame = 1
Query:  457 KDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELR-----EMLDQESDGQWLTVFAPSNTAW------EAAK-SKYGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVL 1254
            +D  V  F  LLE+      L  E   ++YT+L     D+     F           +  H+ + R  S++  NG   +TL+    L+V  Y   L  I+   +   D  A+NG I  +  P+ P       R T++  ++ D    + +  + S LR     E L    D   LT+FAP+N A+      E A+ S+   ++  L+ +H+ + ++    +    T+L  +L+    GV+    +   ++ +   K  +I+ D+++ NGV+ +ID VL
Sbjct:  313 EDSGVNTFMDLLEESGAKAQLQHE---ESYTLLT--VKDSAVTESFTADRGEKLKQKMLAHVVRGRYLSDRLFNGQRLETLAGG-TLRVFIYHRALC-IESSCVDTKDRTARNGAIFILDKPLPPP-----PRSTLMNMLEAD----TRFTMLVSLLRTAGFAEKLSMPVD---LTIFAPTNEAFGTLPVAELARLSRNSKELQELLLSHVSSGILVRGGLIPIGTNLVMALS----GVNIDVTQKGGVM-SINEKQTVIEADIMATNGVIHVIDGVL 566          
BLAST of Periostin vs. Ensembl Sea Lamprey
Match: tgfbi (transforming growth factor, beta-induced [Source:ZFIN;Acc:ZDB-GENE-030131-73])

HSP 1 Score: 63.5438 bits (153), Expect = 1.122e-10
Identity = 52/198 (26.26%), Postives = 92/198 (46.46%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEE-NGRDTYTVLAPYSDDAMKLGEFDL----SNVGG-FPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITP 831
            N CA ++   G     F +C   +++  C   TT  Y+CCPGF  S   +  C  +  +  +    L+       A   +++SQ  +L  E +G  T T  AP ++   +L    L    SNV     + +  H+   R+ ++   +G+T  ++ +   + V  Y NG++ ++C  L+ P++ A NGV+H I   I P
Sbjct:   42 NTCA-VQQIDGTSKRYFSSCKSWYQKKICGKPTTVSYECCPGFI-SIEGEKGCPAIAPLSNVFRT-LETVD----ATATQEYSQRAELRGELDGHATVTYFAPQNEGWTELPTEVLDALVSNVNRELRNALYYHMVNRRLLASDLKHGSTLTSMYEKLGVMVHHYPNGIITVNCARLLKPNNLATNGVVHVIDRVIAP 232          

HSP 2 Score: 59.3066 bits (142), Expect = 2.772e-9
Identity = 65/264 (24.62%), Postives = 123/264 (46.59%), Query Frame = 1
Query:  514 DLFEENG-------RDTYTVLAPYSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSE-LREMLDQESDGQWLTVFAPSNTAWEA-AKSKYG------SKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVP 1260
            D+F E G        + YT+LAP ++       F+LS+       +  H+ K ++   Q  NG   +TL    K+++  Y   +  I+   +     E + G++H I+  I  HV      ++ L+ +Q D   ++    I++  L E L   S G+ LT+FAP+N A+ A  K++         ++  L+  H+ + ++ +  I   A ++  +L    L ++ S D S  +     N  ++++ DL++ +G + II  VL P
Sbjct:  398 DMFAEAGLKGSLKPGEAYTLLAPKNEAFSDTTIFELSD--DIAELLKNHVIKGQVSLYQLYNGQELETLGGK-KIRIFIYRKAIC-IENSCVSTMGKEGRLGILHVINKLI--HV----PERSFLEILQADRRFSTLVELIRTAGLTEKL--RSAGR-LTLFAPTNEAFAALPKAELNRLKGNPKELEALLNFHLASEVLVSGGIVGGAKNVLRTLHGGLLEIESSKDGSVLV-----NGKKVVESDLMATSGAIHIISGVLTP 643          
BLAST of Periostin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009717.1 (pep scaffold:Pmarinus_7.0:GL479096:23086:35405:1 gene:ENSPMAG00000008781.1 transcript:ENSPMAT00000009717.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.9954 bits (136), Expect = 4.352e-9
Identity = 43/203 (21.18%), Postives = 85/203 (41.87%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFA-KLLEKHSQIKDLFEE-NGRDTYTVLAPYSDDAMKL-GEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQR 855
            N+CA  +   G     F +C + +++  C    T  Y+CCPG+          S       I+P++    +V     K+ +      DL  + +G   YT   P ++   ++    +L +       +  H    R+ S    +G+   ++     + V    NG++ ++C  ++ P+  A NGV+H + G I P V +  ++
Sbjct:   43 NMCAVQQIENG--KKYFSSCQLWYRKKICNRPATVSYECCPGYV-------SLSGQTGCPAIVPLNSIYKTVDGLGIKVTKARVDKADLGSDLDGPGAYTFFMPTNEAWERIPAAAELEDPAVLKSLLLSHAVNKRLLSRHLKSGSALASMQSGRSIYVQQSPNGILTVNCVRVIKPNILATNGVLHMVDG-IIPRVSNNIRK 235          
BLAST of Periostin vs. Ensembl Nematostella
Match: EDO48508 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ38])

HSP 1 Score: 66.2402 bits (160), Expect = 2.846e-11
Identity = 123/581 (21.17%), Postives = 217/581 (37.35%), Query Frame = 1
Query:  208 RYTPVAKELAQPFKE--TNLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTF--EYQCCPGFTKSPLVDNQ--CSEVESVWKIIPVHL-KDYSVPKFAKLLEKHSQIKDLFEENGRDT-YTVLAPYSDDAMKLGEFDLSNVGGFPHPIT----MHIWKNRMYSNQFVNGATFKTLS--DDHKLKVTTYSNGLV-FIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKISLLVKNHILNRMICAQAITKK------ATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFA----------QGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQN 1857
            R  P   ++ QP K+   N+C    P  G+        G   ++  C S T    +Y CCPGF +   V  +  C E   V K+  V + K   + +F KL+     + +L  E   DT YT   P ++    +    L  +   P  +      H+   ++ S    +    +T+   +D ++ V   ++  V  +    ++  +  A NG+IH I   I P  G+      ++  +  +P  +  Y  + S  R M         +T+FAPSN A ++     G    LL     L + +    + +        T    SL   ++GV   +D +   L+   N A +   D+ + +GV+ +ID  L+P  AM   +AV  L      + ++  L+ S          + + LL PT++A + +                     +VL YHV+  +  T  F      DS                   +G+KL  N  R  KL     A            +I  +  + IP  +T+  ++   P        L+ +     +K+   ++   A  N
Sbjct:   40 RRLPEQPDIHQPLKKDGLNVCEMRVPV-GMSQECVLEQG--LRRLKCRSVTHHRTDYVCCPGFAR---VKGKPGCPEELYVSKMNIVEVAKSLGLSEFVKLV----NLAELGSELVLDTKYTAFIPSNEAIKSIPAKTLEALAADPKKLRDVLLFHVLPEKVVSEALKHNMLLQTMDPPNDIRVNVNERTHPQVKVVQGAKIIQANQGASNGIIHVIDRVIFPSSGN------LMSYLNENPQLSMLYEVLNS--RNMTLSN-----VTLFAPSNAALQSLPP--GRLDKLLKNKQCLQKFLTYHVLPEPLYSPVLRTCRWKSLEGSFVGVMYGADNTS--LEV--NDAMVTIGDVSTTDGVIHVIDKPLMPYGAMDLVEAVKSLKL----NTLAKLLEDSGLAKTLATIDTSFTLLAPTDKAFSAVPADVMADLSRDAEKLK-----KVLTYHVIGRRVWTYEFGRDTLVDS------------------LEGTKLRLNTFRLGKLHSVNGACLSRSNLETCNSVIHVISSVLIPEQRTLYDIVRNEPQFTTLARILEKSSLSDMLKNSSRSITLFAPTN 564          
BLAST of Periostin vs. Ensembl Nematostella
Match: EDO37200 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGF8])

HSP 1 Score: 61.2326 bits (147), Expect = 3.579e-10
Identity = 53/219 (24.20%), Postives = 98/219 (44.75%), Query Frame = 1
Query:  628 ITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQW-LTVFAPSNTAWEAAKSKYGSKI-------SLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVP 1260
            +  H+ K ++YS+   N     +L +D +++   Y   +V   C  +   +  A NGV+H +S  + P +        ++  ++  P    F   + + +   LD   +G+   TVFAPSN A+     +   KI       + +++ H+++   C+  +T KA            G D +   S+       NKA+++  D    NGVV +ID+VL+P
Sbjct:   81 LMFHVLKGKVYSSAIKNDLLVASL-EDSEIRFNIYGK-IVTAQCSLITKVNLNASNGVLHELSRVMVPPL-----YGNIVGFVREQP--QHFSTLLAAVVEATLDGVLEGEGPFTVFAPSNAAFTKIPKEELDKILHNIPLLTKILEYHVVSGTFCSAGLTDKAK------VETLSGSDVTIHVSKG--GVMVNKAKVVFSDAPVSNGVVHVIDTVLIP 282          
BLAST of Periostin vs. Ensembl Medaka
Match: postn (periostin [Source:NCBI gene;Acc:101165439])

HSP 1 Score: 109.383 bits (272), Expect = 3.799e-24
Identity = 95/355 (26.76%), Postives = 166/355 (46.76%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDN--QCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSD--------DAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSK-------ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSA 1269
            N+CA L+   G     F TC    K + C  +    Y+CCPG+ K   +      + ++ V+  + + +K  +  ++       SQ++   E  G  + T+ AP +D        + +KL E +        + +  H    R+ +    NG    T+S+DH L +  Y NG+V ++C  ++  +  A NG +H I   I P  G+    K +L+  +N+ L++       ++L   LD+  +    T+F P++ A++   S Y  +       I+ LVK H+LN + CA+AI   A S+  +     + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL P SA
Sbjct:   42 NVCA-LQQVMGTSKKYFSTCRNWHKGSICGKKAVVLYECCPGYMKIEGMKGCPAAAPIDDVYGTLGL-VKATATQQYTN----ESQLRGDIE--GPTSVTLFAPSNDAWDLLDPNEKLKLAENENQE---LYNTLLFHTVNQRLVTKDMKNGLVVPTMSEDHNLYINHYGNGVVTVNCARIIYGNQVATNGAVHVIDRVIRPVSGT---IKDILE--ENENLSSFATAASAADL---LDKLGEAGHYTLFVPTDEAFDKLPSGYLERIIENNAVITALVKYHLLNSVQCAEAIM--AGSVYETEEGSSIEIGCDGD----FLTVNGIKM-VLKKDIVTSNGVIHLIDQVLFPDSA 370          
BLAST of Periostin vs. Ensembl Medaka
Match: postn (periostin [Source:NCBI gene;Acc:101165439])

HSP 1 Score: 109.383 bits (272), Expect = 3.948e-24
Identity = 95/355 (26.76%), Postives = 166/355 (46.76%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDN--QCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSD--------DAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSK-------ISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSA 1269
            N+CA L+   G     F TC    K + C  +    Y+CCPG+ K   +      + ++ V+  + + +K  +  ++       SQ++   E  G  + T+ AP +D        + +KL E +        + +  H    R+ +    NG    T+S+DH L +  Y NG+V ++C  ++  +  A NG +H I   I P  G+    K +L+  +N+ L++       ++L   LD+  +    T+F P++ A++   S Y  +       I+ LVK H+LN + CA+AI   A S+  +     + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL P SA
Sbjct:   42 NVCA-LQQVMGTSKKYFSTCRNWHKGSICGKKAVVLYECCPGYMKIEGMKGCPAAAPIDDVYGTLGL-VKATATQQYTN----ESQLRGDIE--GPTSVTLFAPSNDAWDLLDPNEKLKLAENENQE---LYNTLLFHTVNQRLVTKDMKNGLVVPTMSEDHNLYINHYGNGVVTVNCARIIYGNQVATNGAVHVIDRVIRPVSGT---IKDILE--ENENLSSFATAASAADL---LDKLGEAGHYTLFVPTDEAFDKLPSGYLERIIENNAVITALVKYHLLNSVQCAEAIM--AGSVYETEEGSSIEIGCDGD----FLTVNGIKM-VLKKDIVTSNGVIHLIDQVLFPDSA 370          
BLAST of Periostin vs. Ensembl Medaka
Match: postn (periostin [Source:NCBI gene;Acc:101154884])

HSP 1 Score: 105.916 bits (263), Expect = 3.437e-23
Identity = 110/404 (27.23%), Postives = 191/404 (47.28%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDN--QCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDL-----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKIS-------LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSK-SDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHT 1419
            N+CA L+   G     F TC   +    C  + T  Y+CCPG+ K   +      + ++ V+  + + +K  S  K+A + +   +I+      G  ++T  AP S++A +L + D+     SNV     + +  H+   R+ +    NG T  ++ +D  L +  YSNG+V ++C  +++ +  A NGV+H I   I+  +G+  Q    ++    D LT        S L E L Q   G + T+FAP+N A++   S    ++         L+  H+L+ + C++AI   ++    +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P    SAK  +  L +  S   D+ S L  S S    + S ++Y  L P N+  T
Sbjct:   40 NVCA-LQQVMGTKKKYFSTCRNWYHGAICGKKATVLYECCPGYIKLDGMRGCPAVAPIDHVYGSLGI-VKASSTQKYADISKVRPEIE------GSGSFTFFAP-SNEAWELLDEDVRNALVSNVNIELYNALHYHMANKRLLTKDLKNGMTITSMYNDLDLHINHYSNGVVTVNCARIISGNQIATNGVVHVIDRVISA-IGNSMQDVIEVE----DDLTTLSDLAQTSGLLEKLGQP--GHY-TLFAPTNDAFDKLGSDVLERLQSDKEVLKALLSFHLLDSVQCSEAIMVGSSY--ETLEGNSIEIGCDGDS----LTVNGVK-MVLKKDIVTKNGVIHLIDQVLLPD---SAKQVMELLGSSQSTFGDMISELGISTS----MASDAEYTFLAPLNDVFT 412          

HSP 2 Score: 60.4622 bits (145), Expect = 5.238e-9
Identity = 72/297 (24.24%), Postives = 131/297 (44.11%), Query Frame = 1
Query:  448 VHLKDYSV-PKFAK-----LLEKHSQIKDLFEENGRDT-------YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSE-LREMLDQESDGQWLTVFAPSNTAW--------EAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVP 1260
            +HL D  + P  AK     L    S   D+  E G  T       YT LAP    ++D+ M + + DL  +      +  H++KN++   Q  NG   +T++    L+V  Y    V I+   L+    E  NG +H +   + P        KT+ + ++ +     F + +++  L ++L QE      T+FAPS+ A+        E  KS   +  ++L+  H+ N +  +  +    T+L  SL    L +  ++  ++       N  ++ + D+++ NGVV  ++ VL P
Sbjct:  356 IHLIDQVLLPDSAKQVMELLGSSQSTFGDMISELGISTSMASDAEYTFLAPLNDVFTDEVMSIDQDDLRVI------LENHVFKNKIMLGQLYNGQLLETIA-GKTLRVFIYRTA-VCIENSCLIRGTKEGANGALHLMKTLLKP------AAKTMFEILKQNGNFKIFLSLMEAAGLTDVLRQEGS---FTLFAPSDKAFASLATRDLELLKSNKNALKTILLY-HLTNAVFVSGGLEVGVTNLLKSLQGSSLKLIFANSTTQV------NSVKVPEADIMATNGVVHFVNQVLYP 628          
BLAST of Periostin vs. Ensembl Medaka
Match: postn (periostin [Source:NCBI gene;Acc:101154884])

HSP 1 Score: 105.916 bits (263), Expect = 3.576e-23
Identity = 110/404 (27.23%), Postives = 191/404 (47.28%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDN--QCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDL-----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKIS-------LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSK-SDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHT 1419
            N+CA L+   G     F TC   +    C  + T  Y+CCPG+ K   +      + ++ V+  + + +K  S  K+A + +   +I+      G  ++T  AP S++A +L + D+     SNV     + +  H+   R+ +    NG T  ++ +D  L +  YSNG+V ++C  +++ +  A NGV+H I   I+  +G+  Q    ++    D LT        S L E L Q   G + T+FAP+N A++   S    ++         L+  H+L+ + C++AI   ++    +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P    SAK  +  L +  S   D+ S L  S S    + S ++Y  L P N+  T
Sbjct:   40 NVCA-LQQVMGTKKKYFSTCRNWYHGAICGKKATVLYECCPGYIKLDGMRGCPAVAPIDHVYGSLGI-VKASSTQKYADISKVRPEIE------GSGSFTFFAP-SNEAWELLDEDVRNALVSNVNIELYNALHYHMANKRLLTKDLKNGMTITSMYNDLDLHINHYSNGVVTVNCARIISGNQIATNGVVHVIDRVISA-IGNSMQDVIEVE----DDLTTLSDLAQTSGLLEKLGQP--GHY-TLFAPTNDAFDKLGSDVLERLQSDKEVLKALLSFHLLDSVQCSEAIMVGSSY--ETLEGNSIEIGCDGDS----LTVNGVKM-VLKKDIVTKNGVIHLIDQVLLPD---SAKQVMELLGSSQSTFGDMISELGISTS----MASDAEYTFLAPLNDVFT 412          

HSP 2 Score: 60.8474 bits (146), Expect = 4.145e-9
Identity = 72/297 (24.24%), Postives = 131/297 (44.11%), Query Frame = 1
Query:  448 VHLKDYSV-PKFAK-----LLEKHSQIKDLFEENGRDT-------YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSE-LREMLDQESDGQWLTVFAPSNTAW--------EAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVP 1260
            +HL D  + P  AK     L    S   D+  E G  T       YT LAP    ++D+ M + + DL  +      +  H++KN++   Q  NG   +T++    L+V  Y    V I+   L+    E  NG +H +   + P        KT+ + ++ +     F + +++  L ++L QE      T+FAPS+ A+        E  KS   +  ++L+  H+ N +  +  +    T+L  SL    L +  ++  ++       N  ++ + D+++ NGVV  ++ VL P
Sbjct:  356 IHLIDQVLLPDSAKQVMELLGSSQSTFGDMISELGISTSMASDAEYTFLAPLNDVFTDEVMSIDQDDLRVI------LENHVFKNKIMLGQLYNGQLLETIA-GKTLRVFIYRTA-VCIENSCLIRGTKEGANGALHLMKTLLKP------AAKTMFEILKQNGNFKIFLSLMEAAGLTDVLRQEGS---FTLFAPSDKAFASLATRDLELLKSNKNALKTILLY-HLTNAVFVSGGLEVGVTNLLKSLQGSSLKLIFANSTTQV------NSVKVPEADIMATNGVVHFVNQVLYP 628          
BLAST of Periostin vs. Ensembl Medaka
Match: postn (periostin [Source:NCBI gene;Acc:101154884])

HSP 1 Score: 105.916 bits (263), Expect = 3.687e-23
Identity = 110/404 (27.23%), Postives = 191/404 (47.28%), Query Frame = 1
Query:  256 NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDN--QCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDL-----SNVG-GFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKIS-------LLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSK-SDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHT 1419
            N+CA L+   G     F TC   +    C  + T  Y+CCPG+ K   +      + ++ V+  + + +K  S  K+A + +   +I+      G  ++T  AP S++A +L + D+     SNV     + +  H+   R+ +    NG T  ++ +D  L +  YSNG+V ++C  +++ +  A NGV+H I   I+  +G+  Q    ++    D LT        S L E L Q   G + T+FAP+N A++   S    ++         L+  H+L+ + C++AI   ++    +L    + + C  D     L   G K  ++K+D+V+ NGV+ +ID VL+P    SAK  +  L +  S   D+ S L  S S    + S ++Y  L P N+  T
Sbjct:   40 NVCA-LQQVMGTKKKYFSTCRNWYHGAICGKKATVLYECCPGYIKLDGMRGCPAVAPIDHVYGSLGI-VKASSTQKYADISKVRPEIE------GSGSFTFFAP-SNEAWELLDEDVRNALVSNVNIELYNALHYHMANKRLLTKDLKNGMTITSMYNDLDLHINHYSNGVVTVNCARIISGNQIATNGVVHVIDRVISA-IGNSMQDVIEVE----DDLTTLSDLAQTSGLLEKLGQP--GHY-TLFAPTNDAFDKLGSDVLERLQSDKEVLKALLSFHLLDSVQCSEAIMVGSSY--ETLEGNSIEIGCDGDS----LTVNGVK-MVLKKDIVTKNGVIHLIDQVLLPD---SAKQVMELLGSSQSTFGDMISELGISTS----MASDAEYTFLAPLNDVFT 412          

HSP 2 Score: 61.2326 bits (147), Expect = 3.438e-9
Identity = 72/297 (24.24%), Postives = 131/297 (44.11%), Query Frame = 1
Query:  448 VHLKDYSV-PKFAK-----LLEKHSQIKDLFEENGRDT-------YTVLAP----YSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSE-LREMLDQESDGQWLTVFAPSNTAW--------EAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVP 1260
            +HL D  + P  AK     L    S   D+  E G  T       YT LAP    ++D+ M + + DL  +      +  H++KN++   Q  NG   +T++    L+V  Y    V I+   L+    E  NG +H +   + P        KT+ + ++ +     F + +++  L ++L QE      T+FAPS+ A+        E  KS   +  ++L+  H+ N +  +  +    T+L  SL    L +  ++  ++       N  ++ + D+++ NGVV  ++ VL P
Sbjct:  356 IHLIDQVLLPDSAKQVMELLGSSQSTFGDMISELGISTSMASDAEYTFLAPLNDVFTDEVMSIDQDDLRVI------LENHVFKNKIMLGQLYNGQLLETIA-GKTLRVFIYRTA-VCIENSCLIRGTKEGANGALHLMKTLLKP------AAKTMFEILKQNGNFKIFLSLMEAAGLTDVLRQEGS---FTLFAPSDKAFASLATRDLELLKSNKNALKTILLY-HLTNAVFVSGGLEVGVTNLLKSLQGSSLKLIFANSTTQV------NSVKVPEADIMATNGVVHFVNQVLYP 628          
BLAST of Periostin vs. Planmine SMEST
Match: SMESG000070985.1 (SMESG000070985.1)

HSP 1 Score: 1380.93 bits (3573), Expect = 0.000e+0
Identity = 674/680 (99.12%), Postives = 677/680 (99.56%), Query Frame = 1
Query:  136 MFAGFYILSVLLIVVNAQVNPKYPRYTPVAKELAQPFKETNLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWGSSELNRLFQLHTIKMELWGSDMGYFYPETLSTLNSAYLESGNPFQLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWIIDWPLKFRD 2175
            MFAGFYILSVLLIVVNAQVNPKYPRYTPVAKELAQPFKE NLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDLSNVGGFPHPITMHI KNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELRE+LDQESDGQWLTVFAPSNTAWEAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGD KSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYSNENSQMSSNEEYKCQVLRYHVLKMKGDTPAFVNQMSFD+NLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWGSSELNRLFQLHTIKMELWGSDMGYFYPETLST+NSAYLESGNPFQLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWIIDWPLKFRD
Sbjct:    1 MFAGFYILSVLLIVVNAQVNPKYPRYTPVAKELAQPFKEPNLCAFLKPSQGLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVWKIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKLGEFDLSNVGGFPHPITMHIGKNRMYSNQFVNGATFKTLSDDHKLKVTTYSNGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQNDPLTNSFYNDIQSELREILDQESDGQWLTVFAPSNTAWEAAKSKYGSKISLLVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDPKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYSNENSQMSSNEEYKCQVLRYHVLKMKGDTPAFVNQMSFDTNLDNGGKPLSVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWGSSELNRLFQLHTIKMELWGSDMGYFYPETLSTVNSAYLESGNPFQLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWIIDWPLKFRD 680          
BLAST of Periostin vs. Planmine SMEST
Match: SMESG000036036.1 (SMESG000036036.1)

HSP 1 Score: 169.859 bits (429), Expect = 8.259e-46
Identity = 106/343 (30.90%), Postives = 178/343 (51.90%), Query Frame = 1
Query: 1159 RSILDACGNKARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVS---CLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPL-SVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDS-RIKSFGHNVLFLAWQNHGWQTRKEKE-------WGSSELNRLFQLHTIKMELWGSDMGYFYPETLSTLNSAYLESGNPFQLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWII 2151
            R + D CG+K++ + +D ++ NGV  II+  L+P SAMS  D ++   C S+   K++   F +  + CDL +    KY +L+P + +  W +  S++  E S+   ++EY+C+V RYH+++   +     + M          + L   V YF+KDRD S LYF+ +     +  KF  G ++ + RIN+ P K ++ +L E P++K ++ ++Q    D    K      LFLA  + G +     +       +    L     LHT+ + LWG D+GYF P T+    S    SG   +L    + N  + IGY+GLP E W+ V++ NLH  DG++W++
Sbjct:    2 RYVSDLCGSKSKFVSQDNMAANGVYHIIEKPLIPLSAMSFNDILNNPKCASSNFFKAN--KFFEFIKGCDLLMKPGKKYAILMPIDRSFDWWKGYSQFQPEYSRFLKDKEYRCRVARYHIVEQNPELEKLSSLMHEQKGYKTNNRDLLHEVDYFLKDRDHSDLYFHFSPVMDFKSDKFRDGSLYRISRINVIPEKFIVDILKEHPNLKTSSSQVQKADMDKLEFKPRRPLSLFLATLDEGLKDLTTGKIDKIIAGYDGKALKNYLLLHTVPLYLWGGDIGYFKPNTVQRFMS---RSG--IELIFWMDKNQVMRIGYDGLPKEKWAEVVKFNLHAKDGIVWLL 337          
BLAST of Periostin vs. Planmine SMEST
Match: SMESG000036036.1 (SMESG000036036.1)

HSP 1 Score: 154.836 bits (390), Expect = 9.209e-41
Identity = 100/325 (30.77%), Postives = 166/325 (51.08%), Query Frame = 1
Query: 1213 VSGNGVVQIIDSVLVPTSAMSAKDAVS---CLSTGDSKSDVSSFLQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYXXXXXXXXXXXXYKCQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPL-SVVTYFVKDRDGSKLYFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEKLQDTGYDS-RIKSFGHNVLFLAWQNHGWQTRKEKE-------WGSSELNRLFQLHTIKMELWGSDMGYFYPETLSTLNSAYLESGNPFQLQIKRELNGNIFIGYEGLPFELWSLVIESNLHGTDGMLWII 2151
            ++ NGV  II+  L+P SAMS  D ++   C S+   K++   F +  + CDL +    KY +L+P + +  W +  S++  E S+   ++EY+C+V RYH+++   +     + M          + L   V YF+KDRD S LYF+ +     +  KF  G ++ + RIN+ P K ++ +L E P++K ++ ++Q    D    K      LFLA  + G +     +       +    L     LHT+ + LWG D+GYF P T+    S    SG   +L    + N  + IGY+GLP E W+ V++ NLH  DG++W++
Sbjct:    1 MAANGVYHIIEKPLIPLSAMSFNDILNNPKCASSNFFKAN--KFFEFIKGCDLLMKPGKKYAILMPIDRSFDWWKGYSQFQPEYSRFLKDKEYRCRVARYHIVEQNPELEKLSSLMHEQKGYKTNNRDLLHEVDYFLKDRDHSDLYFHFSPVMDFKSDKFRDGSLYRISRINVIPEKFIVDILKEHPNLKTSSSQVQKADMDKLEFKPRRPLSLFLATLDEGLKDLTTGKIDKIIAGYDGKALKNYLLLHTVPLYLWGGDIGYFKPNTVQRFMS---RSG--IELIFWMDKNQVMRIGYDGLPKEKWAEVVKFNLHAKDGIVWLL 318          
The following BLAST results are available for this feature:
BLAST of Periostin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TGFBI1.128e-2423.43transforming growth factor beta induced [Source:HG... [more]
POSTN6.368e-2425.64periostin [Source:HGNC Symbol;Acc:HGNC:16953][more]
POSTN6.451e-2426.07periostin [Source:HGNC Symbol;Acc:HGNC:16953][more]
POSTN7.404e-2425.64periostin [Source:HGNC Symbol;Acc:HGNC:16953][more]
POSTN7.474e-2425.64periostin [Source:HGNC Symbol;Acc:HGNC:16953][more]
back to top
BLAST of Periostin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Periostin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fas15.677e-623.75gene:FBgn0285925 transcript:FBtr0333726[more]
Fas15.880e-624.24gene:FBgn0285925 transcript:FBtr0300037[more]
Fas15.932e-624.24gene:FBgn0285925 transcript:FBtr0300036[more]
mfas6.119e-618.77gene:FBgn0260745 transcript:FBtr0082491[more]
mfas6.119e-618.77gene:FBgn0260745 transcript:FBtr0082492[more]
back to top
BLAST of Periostin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
postnb1.107e-2428.75periostin, osteoblast specific factor b [Source:ZF... [more]
postnb1.174e-2428.75periostin, osteoblast specific factor b [Source:ZF... [more]
postnb1.322e-2428.75periostin, osteoblast specific factor b [Source:ZF... [more]
postnb1.326e-2428.75periostin, osteoblast specific factor b [Source:ZF... [more]
postna1.946e-2426.21periostin, osteoblast specific factor a [Source:ZF... [more]
back to top
BLAST of Periostin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
postn7.581e-2726.89periostin, osteoblast specific factor [Source:NCBI... [more]
postn1.558e-2627.43periostin, osteoblast specific factor [Source:NCBI... [more]
postn1.812e-2627.43periostin, osteoblast specific factor [Source:NCBI... [more]
postn1.844e-2627.43periostin, osteoblast specific factor [Source:NCBI... [more]
postn1.908e-2627.43periostin, osteoblast specific factor [Source:NCBI... [more]
back to top
BLAST of Periostin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Postn1.231e-2426.44periostin, osteoblast specific factor [Source:MGI ... [more]
Postn1.524e-2426.44periostin, osteoblast specific factor [Source:MGI ... [more]
Postn1.753e-2426.44periostin, osteoblast specific factor [Source:MGI ... [more]
Postn2.070e-2426.44periostin, osteoblast specific factor [Source:MGI ... [more]
Tgfbi4.740e-2423.33transforming growth factor, beta induced [Source:M... [more]
back to top
BLAST of Periostin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q95215|BGH3_RABIT4.092e-2425.68Transforming growth factor-beta-induced protein ig... [more]
sp|Q15582|BGH3_HUMAN5.417e-2423.43Transforming growth factor-beta-induced protein ig... [more]
sp|Q62009|POSTN_MOUSE1.226e-2326.44Periostin OS=Mus musculus OX=10090 GN=Postn PE=1 S... [more]
sp|Q15063|POSTN_HUMAN3.555e-2325.64Periostin OS=Homo sapiens OX=9606 GN=POSTN PE=1 SV... [more]
sp|P82198|BGH3_MOUSE4.062e-2323.33Transforming growth factor-beta-induced protein ig... [more]
back to top
BLAST of Periostin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0RIM61.993e-12034.20Gynecophoral canal protein OS=Fasciola hepatica OX... [more]
A0A4S2LDH21.141e-11832.02Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A4S2LCW85.268e-11831.88Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A0R3SA452.517e-11735.16Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A074YWU22.717e-11231.57Fasciclin domain protein OS=Opisthorchis viverrini... [more]
back to top
BLAST of Periostin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
postna1.499e-2728.43periostin [Source:NCBI gene;Acc:103035536][more]
postna1.763e-2728.43periostin [Source:NCBI gene;Acc:103035536][more]
tgfbi2.283e-2323.71transforming growth factor beta induced [Source:NC... [more]
postnb5.657e-2324.73periostin, osteoblast specific factor b [Source:ZF... [more]
back to top
BLAST of Periostin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tgfbi8.365e-1822.80transforming growth factor, beta-induced [Source:Z... [more]
tgfbi1.122e-1026.26transforming growth factor, beta-induced [Source:Z... [more]
ENSPMAT00000009717.14.352e-921.18pep scaffold:Pmarinus_7.0:GL479096:23086:35405:1 g... [more]
back to top
BLAST of Periostin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Periostin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO485082.846e-1121.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO372003.579e-1024.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Periostin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
postn3.799e-2426.76periostin [Source:NCBI gene;Acc:101165439][more]
postn3.948e-2426.76periostin [Source:NCBI gene;Acc:101165439][more]
postn3.437e-2327.23periostin [Source:NCBI gene;Acc:101154884][more]
postn3.576e-2327.23periostin [Source:NCBI gene;Acc:101154884][more]
postn3.687e-2327.23periostin [Source:NCBI gene;Acc:101154884][more]
back to top
BLAST of Periostin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000070985.10.000e+099.12SMESG000070985.1[more]
SMESG000036036.18.259e-4630.90SMESG000036036.1[more]
SMESG000036036.19.209e-4130.77SMESG000036036.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034597 ID=SMED30034597|Name=Periostin|organism=Schmidtea mediterranea sexual|type=transcript|length=2315bp
GAGTGAGCCTAGATATAATCAGTGATAATTGAGCTTTGATAACCATGTTC
TCAAAAATGACCTTATGAAGAGTGAAAAGTAATGTTATAAATCGAAATAA
AAATGAAGACCATTTAAGTATACGGTTATTTGAAAATGTTTGCTGGTTTT
TATATATTAAGCGTCTTGCTTATCGTTGTAAATGCTCAAGTGAATCCTAA
GTATCCTAGATATACTCCAGTCGCGAAAGAATTAGCTCAGCCATTTAAAG
AAACTAATCTTTGTGCGTTTTTAAAACCGAGTCAAGGTTTACTACCATAT
TCATTTTGGACTTGTGGAGTTCCATTTAAACAAACTTATTGTGAGTCGGA
AACCACATTTGAATATCAGTGCTGTCCCGGTTTCACCAAAAGTCCTTTAG
TTGACAATCAGTGTTCAGAGGTAGAATCAGTTTGGAAAATAATTCCTGTT
CACTTGAAAGATTATTCGGTTCCGAAATTCGCAAAATTGTTAGAAAAGCA
TTCTCAAATTAAAGACCTATTTGAAGAAAATGGACGTGACACTTATACAG
TACTTGCACCATACAGTGATGATGCAATGAAACTGGGTGAATTTGATTTA
TCGAATGTCGGCGGATTTCCTCATCCAATTACAATGCACATATGGAAAAA
CCGTATGTATTCAAACCAATTTGTTAATGGTGCGACTTTTAAAACACTTT
CGGACGATCACAAATTAAAAGTGACAACTTATTCCAATGGACTTGTCTTC
ATCGATTGTCGGGCTTTAGTTAATCCAGATCATGAAGCTAAGAATGGGGT
CATTCATTATATTTCTGGACCAATTACTCCACATGTTGGATCCGGATATC
AGAGAAAAACGGTATTACAAGCAATGCAAAATGATCCATTAACCAACAGT
TTTTATAACGATATCCAATCAGAATTGAGGGAAATGCTAGACCAAGAAAG
TGATGGTCAGTGGTTGACTGTATTTGCACCATCTAATACCGCATGGGAAG
CAGCTAAGTCAAAATATGGCAGTAAAATATCTTTGCTTGTGAAAAACCAT
ATTTTAAATCGAATGATTTGTGCGCAGGCTATTACAAAAAAAGCGACATC
CCTTGGTCCTTCATTGGCAAATGAGTATCTAGGAGTTGACTGCAGTTCAG
ATAAATCGAGATCTATTCTCGATGCTTGTGGAAACAAGGCAAGAATAATT
AAAGAAGATCTTGTTTCCGGAAATGGAGTAGTACAGATTATCGACTCAGT
ATTAGTTCCAACTTCCGCTATGTCTGCGAAGGATGCTGTATCATGCCTGA
GTACGGGTGATTCTAAATCCGACGTGTCAAGCTTTCTTCAGCATTCCAGA
AGTTGTGACTTGAAAATAAATTCGTTCAGCAAATACATACTTTTAATTCC
CACAAATGAAGCTCATACTTGGCTCCAAGAACAGAGCAAATATTCTAACG
AGAATTCACAAATGTCGTCTAATGAAGAATACAAATGTCAGGTTCTTCGG
TATCATGTGTTAAAAATGAAAGGAGATACTCCAGCTTTCGTCAACCAAAT
GTCATTTGATTCAAATTTGGATAATGGCGGAAAACCACTGAGTGTAGTTA
CATATTTTGTTAAAGACCGAGACGGTTCAAAATTATATTTCAATGCGGCA
AGAACAACAAAATTGGAACCAAGGAAGTTTGCACAGGGAATTATATTCTT
CGTTGACCGAATAAATATTCCACCATCAAAAACAATGATGCAATTGTTAT
CTGAACGGCCTGATGTAAAGCTCACAACCGAAAAGTTACAAGATACTGGT
TATGATTCTAGAATTAAATCGTTTGGTCATAATGTTCTGTTTTTGGCATG
GCAAAATCACGGCTGGCAAACAAGAAAAGAAAAGGAATGGGGCAGCTCAG
AATTGAATCGACTTTTCCAATTGCATACAATTAAAATGGAACTTTGGGGA
TCAGATATGGGATATTTCTATCCCGAGACGCTTTCAACCCTAAATTCAGC
TTATTTGGAGTCTGGAAACCCATTCCAACTGCAGATTAAACGCGAACTGA
ATGGTAATATATTCATAGGCTATGAAGGCTTGCCTTTCGAATTGTGGTCT
TTAGTTATTGAGAGTAATCTTCATGGAACTGACGGAATGTTATGGATCAT
TGACTGGCCCTTGAAATTCAGAGACTGAGACTATAAATGTGATTGTAGGT
ATACAGAAAATTGTCGACAAAAACATGAAATTAATTAAACATTGATTTTT
TTATTAGTTTTTAATCGTTTTGCCCCAAATTTTAATGAATAAAATATCTA
TATGACTATTTTTGG
back to top

protein sequence of SMED30034597-orf-1

>SMED30034597-orf-1 ID=SMED30034597-orf-1|Name=SMED30034597-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=681bp
MFAGFYILSVLLIVVNAQVNPKYPRYTPVAKELAQPFKETNLCAFLKPSQ
GLLPYSFWTCGVPFKQTYCESETTFEYQCCPGFTKSPLVDNQCSEVESVW
KIIPVHLKDYSVPKFAKLLEKHSQIKDLFEENGRDTYTVLAPYSDDAMKL
GEFDLSNVGGFPHPITMHIWKNRMYSNQFVNGATFKTLSDDHKLKVTTYS
NGLVFIDCRALVNPDHEAKNGVIHYISGPITPHVGSGYQRKTVLQAMQND
PLTNSFYNDIQSELREMLDQESDGQWLTVFAPSNTAWEAAKSKYGSKISL
LVKNHILNRMICAQAITKKATSLGPSLANEYLGVDCSSDKSRSILDACGN
KARIIKEDLVSGNGVVQIIDSVLVPTSAMSAKDAVSCLSTGDSKSDVSSF
LQHSRSCDLKINSFSKYILLIPTNEAHTWLQEQSKYSNENSQMSSNEEYK
CQVLRYHVLKMKGDTPAFVNQMSFDSNLDNGGKPLSVVTYFVKDRDGSKL
YFNAARTTKLEPRKFAQGIIFFVDRINIPPSKTMMQLLSERPDVKLTTEK
LQDTGYDSRIKSFGHNVLFLAWQNHGWQTRKEKEWGSSELNRLFQLHTIK
MELWGSDMGYFYPETLSTLNSAYLESGNPFQLQIKRELNGNIFIGYEGLP
FELWSLVIESNLHGTDGMLWIIDWPLKFRD*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0008270zinc ion binding
GO:0005178integrin binding
GO:0005515protein binding
GO:0005518collagen binding
GO:0050840extracellular matrix binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR036378FAS1_dom_sf
IPR000782FAS1_domain
Vocabulary: biological process
TermDefinition
GO:0001525angiogenesis
GO:0002062chondrocyte differentiation
GO:0007155cell adhesion
GO:0007162negative regulation of cell adhesion
GO:0007601visual perception
GO:0008283cell proliferation
GO:0030198extracellular matrix organization
GO:0044267cellular protein metabolic process
GO:0050896response to stimulus
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
GO:0005578proteinaceous extracellular matrix
GO:0005604basement membrane
GO:0005615extracellular space
GO:0005802trans-Golgi network
GO:0005886plasma membrane
GO:0031012extracellular matrix
GO:0070062extracellular exosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000782FAS1 domainSMARTSM00554fasc_3coord: 419..530
e-value: 1.2
score: 5.6
coord: 278..376
e-value: 8.4E-16
score: 68.5
coord: 138..233
e-value: 5.9E-11
score: 52.4
IPR000782FAS1 domainPFAMPF02469Fasciclincoord: 114..232
e-value: 5.7E-13
score: 49.2
coord: 415..526
e-value: 6.4E-6
score: 26.4
coord: 257..375
e-value: 8.6E-15
score: 55.1
IPR000782FAS1 domainPROSITEPS50213FAS1coord: 240..373
score: 18.852
IPR000782FAS1 domainPROSITEPS50213FAS1coord: 99..230
score: 11.943
IPR036378FAS1 domain superfamilyGENE3DG3DSA:2.30.180.10coord: 241..379
e-value: 1.2E-17
score: 66.6
IPR036378FAS1 domain superfamilyGENE3DG3DSA:2.30.180.10coord: 101..230
e-value: 5.7E-11
score: 44.8
IPR036378FAS1 domain superfamilySUPERFAMILYSSF82153FAS1 domaincoord: 512..676
IPR036378FAS1 domain superfamilySUPERFAMILYSSF82153FAS1 domaincoord: 241..376
IPR036378FAS1 domain superfamilySUPERFAMILYSSF82153FAS1 domaincoord: 108..232
IPR036378FAS1 domain superfamilySUPERFAMILYSSF82153FAS1 domaincoord: 411..532
NoneNo IPR availablePANTHERPTHR10900PERIOSTIN-RELATEDcoord: 111..233
coord: 275..401
coord: 395..673
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..17
score: 0.86