Dynein light chain

Overview
NameDynein light chain
Smed IDSMED30034525
Length (bp)803
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Dynein light chain (SMED30034525) t-SNE clustered cells

Violin plots show distribution of expression levels for Dynein light chain (SMED30034525) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynein light chain (SMED30034525) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynein light chain (SMED30034525) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30034525

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30034525h1SMcG0000850 SmedASXL_009150SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30034525h1SMcG0000850 dd_Smed_v4_9661_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30034525h1SMcG0000850 dd_Smed_v4_9661_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30034525h1SMcG0000850 dd_Smed_v4_9661_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL2 (dynein light chain LC8-type 2 [Source:HGNC Symbol;Acc:HGNC:24596])

HSP 1 Score: 62.003 bits (149), Expect = 6.141e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 60.077 bits (144), Expect = 2.876e-11
Identity = 26/74 (35.14%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q +++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 60.077 bits (144), Expect = 2.876e-11
Identity = 26/74 (35.14%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q +++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 60.077 bits (144), Expect = 2.876e-11
Identity = 26/74 (35.14%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q +++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 60.077 bits (144), Expect = 2.876e-11
Identity = 26/74 (35.14%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q +++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 62.003 bits (149), Expect = 2.011e-12
Identity = 28/74 (37.84%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q AID + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAIDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 62.003 bits (149), Expect = 2.011e-12
Identity = 28/74 (37.84%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q AID + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAIDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 62.003 bits (149), Expect = 2.011e-12
Identity = 28/74 (37.84%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q AID + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAIDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-2 (Probable dynein light chain 2, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q21557])

HSP 1 Score: 49.2914 bits (116), Expect = 7.499e-8
Identity = 22/72 (30.56%), Postives = 42/72 (58.33%), Query Frame = 2 
Query:  482 RQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            R   I V  +A + Y ++KD+A  +K++LD+++   WHV+  +  FGS +S++ G F+  K      +I++ 
Sbjct:   18 RDMVISVVREAQRLYNIDKDVAAFVKEELDKKFGATWHVICGK-CFGSRVSYEMGHFILLKCNKVNVMIYKC 88
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-5 (Dynein Light Chain [Source:UniProtKB/TrEMBL;Acc:Q65XS9])

HSP 1 Score: 49.2914 bits (116), Expect = 4.100e-7
Identity = 21/71 (29.58%), Postives = 41/71 (57.75%), Query Frame = 2 
Query:  485 QFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            Q A  ++ ++   Y LE DIA+ +K   D EY   WH +  +  FGSF++ +   F++++I    +++++T
Sbjct:   71 QEACSLAAKSIMTYHLEHDIARHLKMAFDREYGPDWHCICGKH-FGSFVTFEPDSFIYFRIGTIAFMLFKT 140
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0070706)

HSP 1 Score: 62.7734 bits (151), Expect = 1.329e-12
Identity = 28/74 (37.84%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0070704)

HSP 1 Score: 62.7734 bits (151), Expect = 1.329e-12
Identity = 28/74 (37.84%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0307065)

HSP 1 Score: 62.7734 bits (151), Expect = 1.329e-12
Identity = 28/74 (37.84%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: ctp (gene:FBgn0011760 transcript:FBtr0070707)

HSP 1 Score: 62.7734 bits (151), Expect = 1.329e-12
Identity = 28/74 (37.84%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: Cdlc2 (gene:FBgn0026141 transcript:FBtr0077924)

HSP 1 Score: 62.3882 bits (150), Expect = 1.565e-12
Identity = 28/74 (37.84%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGRN-FGSYVTHETRHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll2a (dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:ZDB-GENE-030828-11])

HSP 1 Score: 62.003 bits (149), Expect = 3.320e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll2b (dynein, light chain, LC8-type 2b [Source:ZFIN;Acc:ZDB-GENE-050320-132])

HSP 1 Score: 62.003 bits (149), Expect = 3.320e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll2a (dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:ZDB-GENE-030828-11])

HSP 1 Score: 62.003 bits (149), Expect = 3.320e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll1 (dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1961])

HSP 1 Score: 60.8474 bits (146), Expect = 8.901e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVECATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dynll1 (dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1961])

HSP 1 Score: 60.8474 bits (146), Expect = 8.901e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVECATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll2 (dynein light chain LC8-type 2 [Source:NCBI gene;Acc:100038056])

HSP 1 Score: 62.003 bits (149), Expect = 5.567e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll1 (dynein light chain LC8-type 1 [Source:NCBI gene;Acc:448652])

HSP 1 Score: 60.8474 bits (146), Expect = 1.134e-11
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A+D + QA + + +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVDCATQALEKFNIEKDIAAFIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll2 (dynein light chain LC8-type 2 [Source:MGI Symbol;Acc:MGI:1915347])

HSP 1 Score: 62.003 bits (149), Expect = 4.216e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll2 (dynein light chain LC8-type 2 [Source:MGI Symbol;Acc:MGI:1915347])

HSP 1 Score: 62.003 bits (149), Expect = 4.216e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll2 (dynein light chain LC8-type 2 [Source:MGI Symbol;Acc:MGI:1915347])

HSP 1 Score: 62.003 bits (149), Expect = 4.216e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll1 (dynein light chain LC8-type 1 [Source:MGI Symbol;Acc:MGI:1861457])

HSP 1 Score: 60.077 bits (144), Expect = 1.974e-11
Identity = 26/74 (35.14%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q +++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll1 (dynein light chain LC8-type 1 [Source:MGI Symbol;Acc:MGI:1861457])

HSP 1 Score: 60.077 bits (144), Expect = 1.974e-11
Identity = 26/74 (35.14%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q +++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|P14202|TEGU_SCHMA (Tegument antigen OS=Schistosoma mansoni OX=6183 GN=A12 PE=2 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 1.273e-17
Identity = 52/187 (27.81%), Postives = 94/187 (50.27%), Query Frame = 2 
Query:  143 DLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPS 703
            + I+AF EID D +  I K ELI Y  K   +M  ++ W+  FD +   +I++EEFC   GL+ +E   ++ + K+E      ++ PP  E     I       +  +   +F+++ +D + +   D    +++A  +K  LD  Y ++W VV+   ++    SH+    + +K  N+  L W+TPS
Sbjct:   12 EFIRAFLEIDADSNEMIDKQELIKYCQKYRLDMKLIDPWIARFDTDKDNKISIEEFCRGFGLKVSEIRREKDELKKERDGKFPKL-PPNIE----IIAATMSKTKQYEICCQFKEY-VDNTSRTGNDM---REVANKMKSLLDNTYGRVWQVVLLTGSYWMNFSHEPFLSIQFKYNNYVCLAWRTPS 189
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|P32070|SM21_SCHMA (Antigen Sm21.7 OS=Schistosoma mansoni OX=6183 GN=SM21.7 PE=2 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 1.015e-13
Identity = 45/166 (27.11%), Postives = 82/166 (49.40%), Query Frame = 2 
Query:  224 KKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNE-----DYLQQVQTKQEESKPMIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPSN 706
            K+  +M  VN+W+ +FD +   +IT EEFC  LGL+ NE     ++++ VQ+ +E+S P              E + +           E  Q   D+ ++  KD  + K + K+ K +L+  Y ++W V     ++ +  SH+  + + ++ +N   L W+TPSN
Sbjct:   34 KEKLDMKQVNEWIALFDVDKDQKITFEEFCRGLGLKQNEMRIERNHIKTVQSGREQSLP--------------EGVSIIASTMPKPKQVEVTQLFKDIYNEVKKDPDMNK-VVKTFKSELERRYGRVWQVNAVTHSYWASFSHEPFQSIQFQYDNKIILAWRTPSN 184
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q6BZF8|DYL1_DEBHA (Dynein light chain 1, cytoplasmic OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=DYN2 PE=3 SV=1)

HSP 1 Score: 65.855 bits (159), Expect = 8.778e-13
Identity = 28/67 (41.79%), Postives = 49/67 (73.13%), Query Frame = 2 
Query:  497 DVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            ++S++A  +YK+EKDIA  +KK+LD+ Y   WHV+V +S FGS+++H+ G F ++ I    +LI+++
Sbjct:   25 ELSNEAVSNYKIEKDIATYLKKELDQLYGATWHVIVGKS-FGSYVTHEQGFFTYFYIGQLAFLIFKS 90
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q02647|DYL1_YEAST (Dynein light chain 1, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=DYN2 PE=1 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 3.891e-12
Identity = 27/77 (35.06%), Postives = 52/77 (67.53%), Query Frame = 2 
Query:  470 TAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTP 700
            T + ++  + +S  A   Y+LE+DIA ++KK+LD +Y   WHV+V ++ FGS+++H+ G F+++ I    +L+++T 
Sbjct:   17 TDKLKEDILTISKDALDKYQLERDIAGTVKKQLDVKYGNTWHVIVGKN-FGSYVTHEKGHFVYFYIGPLAFLVFKTA 92
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q6FUJ0|DYL1_CANGA (Dynein light chain 1, cytoplasmic OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) OX=284593 GN=DYN2 PE=3 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 5.349e-12
Identity = 27/74 (36.49%), Postives = 50/74 (67.57%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q    ++ +A +++ LE++IA  IKK++D  Y   WHV+V RS FGS+++H+ GKF+++ +     L+++T
Sbjct:   14 EMQQEVFRIAEEAMREHTLEREIASVIKKEMDSRYGHTWHVIVGRS-FGSYVTHEKGKFVYFYVGPLALLVFKT 86
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A1I8I7N8 (Dynein light chain OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001380g1 PE=3 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 4.105e-40
Identity = 68/187 (36.36%), Postives = 115/187 (61.50%), Query Frame = 2 
Query:  140 MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTP 700
            MD + A+E IDTD+SGEIT +EL  Y  K +YE  FV KW+ +FD +N+G IT+EEFC+ LGL P ++Y+++VQ  +E+S  ++       E+ +               T E ++  + ++  A + ++ E+DIA+ +K +LD ++++ WHV+V R  +GSF +H+ G+  H+ +     L+W+TP
Sbjct:    1 MDFLTAYEAIDTDFSGEITSEELEAYCRKHNYEDKFVEKWLRLFDHDNSGTITIEEFCETLGLVPKQEYMEKVQINREKSSGVMDGVKIITEDPD--------------MTDELKEEIVQLARTAQEQFENERDIARYMKSELDAKFDRAWHVIVGRFQYGSFCTHEVGRLFHFYVVRNAILVWKTP 173
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A267GLS7 (Dynein light chain OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008799g1 PE=3 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 4.514e-40
Identity = 68/197 (34.52%), Postives = 117/197 (59.39%), Query Frame = 2 
Query:  143 DLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKP----------MIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPS 703
            D + AFE IDTD+SGEIT++EL  Y  K++++  FV KW+ +FD +N+G I+++E+CD LGL+PN +Y+++VQ ++  + P          +I +    NE                    +  +  + ++ +A   + +EKDIA  IK +LDE+    W VV+ R  +GSF++H++G  +H+ ++ F +LIW+TP+
Sbjct:    3 DFLTAFESIDTDFSGEITREELEAYCRKQNFDEKFVQKWLNLFDADNSGTISIDEYCDTLGLRPNTEYMEKVQVQRSNAAPADDDWMNGVKVIAVDKALNE--------------------DLMRLIVRLAREAQAKHTVEKDIAMYIKDRLDEKDQAAWQVVLGRFKYGSFVTHENGYMLHFFVDRFAFLIWRTPN 179
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A1I8I0B9 (Dynein light chain OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 145.976 bits (367), Expect = 9.298e-40
Identity = 67/197 (34.01%), Postives = 116/197 (58.88%), Query Frame = 2 
Query:  143 DLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKP----------MIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPS 703
            D + AFE IDTD+SGEIT++EL  Y  K++++  FV KW+ +FD +N+G I+++E+CD LGL+PN +Y+++VQ ++  + P          +I +    +E+                      +  + ++ +A   + +EKDIA  IK +LDE+    W VV+ R  +GSF++H+ G  +H+ ++ F +LIW+TP+
Sbjct:    3 DFLTAFESIDTDFSGEITREELEAYCRKQNFDEKFVQKWLNLFDADNSGTISIDEYCDTLGLRPNTEYMEKVQVQRSNAAPADDDWMNGVKVIAVAEALDED--------------------LMRLIVRLAREAQAKHTVEKDIAMYIKDRLDEKDQAAWQVVLGRFKYGSFVTHEKGYMLHFFVDRFAFLIWRTPN 179
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A267EIW9 (Dynein light chain OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005207g1 PE=3 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 1.188e-39
Identity = 70/195 (35.90%), Postives = 116/195 (59.49%), Query Frame = 2 
Query:  140 MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKP--------MIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTP 700
            MD + AFE+ID+D+SGEIT +EL  Y  + +YE  FV KW+ +FD +N+G IT+EEFCD LGL P ++Y+++VQT +E+S+         +I   P  ++ T                    ++  + ++ QA + +  E+DIA+ +K +LD+ + + WHV+V R  +GSF +H++G   H+ +     L+W+TP
Sbjct:    1 MDFLHAFEDIDSDFSGEITTEELEAYCRRHNYEDRFVEKWLRLFDHDNSGTITIEEFCDTLGLVPKQEYMEKVQTNREKSEGGGIMDGVKIITEDPELSDST--------------------KEEIVRIARQAQEQFVNERDIARHMKARLDDMFGRAWHVIVGRYQYGSFCTHETGSLFHFYVLRNAVLVWKTP 175
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A267EQG8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026868g1 PE=4 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 1.689e-39
Identity = 73/196 (37.24%), Postives = 121/196 (61.73%), Query Frame = 2 
Query:  143 DLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKP---------MIQICPPFNE-ETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTP 700
            D +KAFE IDTD+SGEITK EL  Y  K++++  F+ KW+++FD +N+G IT+EE+C+ LGL PN DY+++V+T++  + P            +    N+ E ++ + +V+I+  D     +  +  + ++ +    Y LEKDIAK IK  LD+   + WH +V R  +GSF +H+ G+ +H  +  F +L+W+TP
Sbjct:    3 DFLKAFEAIDTDFSGEITKQELEEYCKKQEFDDRFIQKWLDLFDADNSGTITVEEYCETLGLTPNTDYIEKVETRRVNAGPPGTGVDEADQYAVQSSGNDGEIDDSLDNVQILAVDDQLPEDLMRTIVRLAREGQAVYSLEKDIAKHIKAGLDDLDGRAWHAIVGRFQYGSFCTHEVGRMLHCFVGRFAFLVWRTP 198
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: ENSAMXT00000047143.1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 62.003 bits (149), Expect = 2.813e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dynll2b (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 62.003 bits (149), Expect = 2.813e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dynll1 (dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1961])

HSP 1 Score: 60.077 bits (144), Expect = 3.034e-11
Identity = 26/64 (40.62%), Postives = 46/64 (71.88%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKI 667
            E +Q A++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +
Sbjct:   16 EMQQDAVECATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYL 78
[Close]
BLAST of Dynein light chain vs. Ensembl Yeast
Match: DYN2 (Cytoplasmic light chain dynein, microtubule motor protein; required for intracellular transport and cell division; involved in mitotic spindle positioning; forms complex with dynein intermediate chain Pac11p that promotes Dyn1p homodimerization, potentiates motor processivity; Dyn2p-Pac11p complex important for interaction of dynein motor complex with dynactin complex; acts as molecular glue to dimerize, stabilize Nup82-Nsp1-Nup159 complex module of cytoplasmic pore filaments [Source:SGD;Acc:S000002832])

HSP 1 Score: 64.3142 bits (155), Expect = 5.604e-14
Identity = 27/77 (35.06%), Postives = 52/77 (67.53%), Query Frame = 2 
Query:  470 TAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTP 700
            T + ++  + +S  A   Y+LE+DIA ++KK+LD +Y   WHV+V ++ FGS+++H+ G F+++ I    +L+++T 
Sbjct:   17 TDKLKEDILTISKDALDKYQLERDIAGTVKKQLDVKYGNTWHVIVGKN-FGSYVTHEKGHFVYFYIGPLAFLVFKTA 92
[Close]
BLAST of Dynein light chain vs. Ensembl Nematostella
Match: EDO44582 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVI5])

HSP 1 Score: 57.7658 bits (138), Expect = 3.533e-11
Identity = 25/69 (36.23%), Postives = 48/69 (69.57%), Query Frame = 2 
Query:  491 AIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            AI+ + QA + + +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   21 AIECATQALEKFNIEKDIAAFIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: ENSORLT00000005747.2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101162462])

HSP 1 Score: 63.1586 bits (152), Expect = 9.786e-13
Identity = 28/74 (37.84%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A+D + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: DYNLL2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101174042])

HSP 1 Score: 62.3882 bits (150), Expect = 1.750e-12
Identity = 27/74 (36.49%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            E +Q A+D + QA + Y +EKDIA  +KK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 EMQQDAVDCAMQAMEKYNIEKDIAAYVKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: dynll1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101171417])

HSP 1 Score: 59.6918 bits (143), Expect = 2.242e-11
Identity = 26/74 (35.14%), Postives = 51/74 (68.92%), Query Frame = 2 
Query:  476 EFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQT 697
            + +Q A++ + QA + Y +EKDIA  IKK+ D++YN  WH +V R+ FGS+++H++  F+++ +     L++++
Sbjct:   16 DMQQDAVECATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRN-FGSYVTHETKHFIYFYLGQVAILLFKS 88
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000008592.1 (SMESG000008592.1)

HSP 1 Score: 357.836 bits (917), Expect = 1.106e-126
Identity = 188/189 (99.47%), Postives = 189/189 (100.00%), Query Frame = 2 
Query:  140 MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPSN 706
            MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNEEIIDVEIIREDPDTTAEFRQFAIDVSHQASKD+KLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPSN
Sbjct:    1 MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNEEIIDVEIIREDPDTTAEFRQFAIDVSHQASKDHKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPSN 189
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000042102.1 (SMESG000042102.1)

HSP 1 Score: 143.28 bits (360), Expect = 3.185e-42
Identity = 76/191 (39.79%), Postives = 121/191 (63.35%), Query Frame = 2 
Query:  140 MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQ---ICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPS 703
            M+ IKAFEEID+D SGEIT+ ELI YM  K+Y+  FV KW+ IFD +N+G ITLEEFC+ LGL PN++Y ++++ ++ E + + +   + P ++         + +I EDP    +F+ F + +  +A+ +      IAK +K  LD ++ + W+VVV    +GSF+SH+ G F+H K+  F  L+W+ P+
Sbjct:    1 MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQKRIEKRKSEKELLKRKSLLIPLYD---------LYVIDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVPA 182
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000081226.1 (SMESG000081226.1)

HSP 1 Score: 119.783 bits (299), Expect = 2.968e-33
Identity = 68/188 (36.17%), Postives = 103/188 (54.79%), Query Frame = 2 
Query:  140 MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPS 703
            M+L+K F EID   +G IT+++L+++  +++    F  KW+ +FD  N G+I +E F   +GL+P EDY+ Q     EES   I+      E+ N                   +   I+ S  A  +Y+ E  +AK IK  LD+ + K+WH VV +S FGS ISH    FMHYKIE+  +LI++TP+
Sbjct:    1 MELLKIFNEIDVGRTGIITEEQLLDFQ-ERNGLNNFAEKWLNMFDVENEGKIRIENFASTVGLEP-EDYVDQTIQNHEESGQFIENVDIIKEDDN--------------MPQNLKDAIINTSIDALNNYEKESQMAKHIKIFLDDNFGKVWHAVVGKSQFGSNISHLPESFMHYKIEDHAFLIFKTPN 172
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000078154.1 (SMESG000078154.1)

HSP 1 Score: 124.02 bits (310), Expect = 1.511e-32
Identity = 62/189 (32.80%), Postives = 108/189 (57.14%), Query Frame = 2 
Query:  134 FQMDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTP 700
              +D +K FEEID D+SGEI+ +E+  YM + ++E  FV+KW+ +F+PN  GRIT+E +C +LGL P E Y  +V      ++ +  + P  N   +   + +  +    D T   + F I ++ +A K+   E +IA+ IK+ LD  +  +W V+V+R  +  ++SH+    +H+ +    + IW+TP
Sbjct:  240 MSLDFLKTFEEIDGDFSGEISYEEISTYMRRHNFEAEFVDKWLTLFEPNKDGRITIESYCGSLGLIPREHYYGRVVA----NRKVGSLIPRGNATEDWANVRIIRLEPLMDDT--MKTFIIRLARKAQKELATEYEIARFIKQSLDLRWGGLWQVIVSRYPYACYLSHEMASLIHFWLLEHSFCIWKTP 422
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000006950.1 (SMESG000006950.1)

HSP 1 Score: 94.3597 bits (233), Expect = 1.551e-23
Identity = 61/186 (32.80%), Postives = 95/186 (51.08%), Query Frame = 2 
Query:  146 LIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNXXXXXXXXXXXXXXTTAEFRQFAIDVSHQASKDYKLE-KDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTP 700
             IKA+ +ID D SG IT DEL  YM + +Y+  FV KW+ +FD +NTGRITLEEFC+ LGL+ + D++ + +T  +ES                  +   +     +         I V  +A + Y    K+ +  IK+ LD      WH ++ +  + ++ S +    +  KIEN  YL+W+TP
Sbjct:    5 FIKAYCQIDKDGSGTITADELRAYMTENNYQEDFVTKWLRLFDRDNTGRITLEEFCETLGLEVS-DFIDK-RTALKESADF--------------SLYNGVNILSSNMVQPNEGIVIQVIRKARELYPNSFKEQSTYIKQNLDLVLETTWHCIITKGQYWAYYSCEPECSLAVKIENIVYLLWRTP 174
The following BLAST results are available for this feature:
BLAST of Dynein light chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DYNLL26.141e-1236.49dynein light chain LC8-type 2 [Source:HGNC Symbol;... [more]
DYNLL12.876e-1135.14dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL12.876e-1135.14dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL12.876e-1135.14dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL12.876e-1135.14dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
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BLAST of Dynein light chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dlc-12.011e-1237.84Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-12.011e-1237.84Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-12.011e-1237.84Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-27.499e-830.56Probable dynein light chain 2, cytoplasmic [Sourc... [more]
dlc-54.100e-729.58Dynein Light Chain [Source:UniProtKB/TrEMBL;Acc:Q... [more]
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BLAST of Dynein light chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctp1.329e-1237.84gene:FBgn0011760 transcript:FBtr0070706[more]
ctp1.329e-1237.84gene:FBgn0011760 transcript:FBtr0070704[more]
ctp1.329e-1237.84gene:FBgn0011760 transcript:FBtr0307065[more]
ctp1.329e-1237.84gene:FBgn0011760 transcript:FBtr0070707[more]
Cdlc21.565e-1237.84gene:FBgn0026141 transcript:FBtr0077924[more]
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BLAST of Dynein light chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dynll2a3.320e-1236.49dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:... [more]
dynll2b3.320e-1236.49dynein, light chain, LC8-type 2b [Source:ZFIN;Acc:... [more]
dynll2a3.320e-1236.49dynein, light chain, LC8-type 2a [Source:ZFIN;Acc:... [more]
dynll18.901e-1236.49dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z... [more]
dynll18.901e-1236.49dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z... [more]
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BLAST of Dynein light chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
dynll25.567e-1236.49dynein light chain LC8-type 2 [Source:NCBI gene;Ac... [more]
dynll11.134e-1136.49dynein light chain LC8-type 1 [Source:NCBI gene;Ac... [more]
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BLAST of Dynein light chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dynll24.216e-1236.49dynein light chain LC8-type 2 [Source:MGI Symbol;A... [more]
Dynll24.216e-1236.49dynein light chain LC8-type 2 [Source:MGI Symbol;A... [more]
Dynll24.216e-1236.49dynein light chain LC8-type 2 [Source:MGI Symbol;A... [more]
Dynll11.974e-1135.14dynein light chain LC8-type 1 [Source:MGI Symbol;A... [more]
Dynll11.974e-1135.14dynein light chain LC8-type 1 [Source:MGI Symbol;A... [more]
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BLAST of Dynein light chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P14202|TEGU_SCHMA1.273e-1727.81Tegument antigen OS=Schistosoma mansoni OX=6183 GN... [more]
sp|P32070|SM21_SCHMA1.015e-1327.11Antigen Sm21.7 OS=Schistosoma mansoni OX=6183 GN=S... [more]
sp|Q6BZF8|DYL1_DEBHA8.778e-1341.79Dynein light chain 1, cytoplasmic OS=Debaryomyces ... [more]
sp|Q02647|DYL1_YEAST3.891e-1235.06Dynein light chain 1, cytoplasmic OS=Saccharomyces... [more]
sp|Q6FUJ0|DYL1_CANGA5.349e-1236.49Dynein light chain 1, cytoplasmic OS=Candida glabr... [more]
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BLAST of Dynein light chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8I7N84.105e-4036.36Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A267GLS74.514e-4034.52Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A1I8I0B99.298e-4034.01Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A267EIW91.188e-3935.90Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A267EQG81.689e-3937.24Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Dynein light chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSAMXT00000047143.12.813e-1236.49dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
dynll2b2.813e-1236.49dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
dynll13.034e-1140.63dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z... [more]
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BLAST of Dynein light chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
DYN25.604e-1435.06Cytoplasmic light chain dynein, microtubule motor ... [more]
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BLAST of Dynein light chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO445823.533e-1136.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Dynein light chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSORLT00000005747.29.786e-1337.84dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
DYNLL21.750e-1236.49dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
dynll12.242e-1135.14dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
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BLAST of Dynein light chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000008592.11.106e-12699.47SMESG000008592.1[more]
SMESG000042102.13.185e-4239.79SMESG000042102.1[more]
SMESG000081226.12.968e-3336.17SMESG000081226.1[more]
SMESG000078154.11.511e-3232.80SMESG000078154.1[more]
SMESG000006950.11.551e-2332.80SMESG000006950.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034525 ID=SMED30034525|Name=Dynein light chain|organism=Schmidtea mediterranea sexual|type=transcript|length=803bp
CGTTCCGATCTTCATTCTCTAAGTTTACACACTGAAAACAAACAAATGAT
CTTAAAGCGAAAAACTATGACAGAGAATGTATAAATATTGTTGACTCGAT
TAGAAACGCATTAATTACAGATTTATATTTAATTTTCAAATGGATCTAAT
CAAAGCATTTGAAGAAATCGACACCGATTACTCTGGTGAAATCACAAAAG
ATGAGTTGATCAATTATATGATTAAAAAAGACTACGAGATGGGTTTTGTT
AATAAATGGATGGAAATTTTCGATCCCAATAATACCGGTAGAATTACTTT
GGAAGAATTTTGTGATGCTCTAGGATTGCAACCGAACGAGGATTATTTAC
AACAAGTACAAACGAAACAAGAAGAATCGAAACCGATGATTCAGATCTGT
CCGCCATTTAATGAAGAAACCAATGAAGAAATAATTGACGTGGAAATCAT
TCGTGAAGATCCTGACACGACCGCGGAATTCAGACAATTCGCTATTGATG
TCTCTCATCAAGCGTCTAAAGATTACAAACTGGAAAAGGATATTGCAAAA
TCTATTAAAAAGAAATTAGATGAAGAATACAATAAAATATGGCATGTAGT
TGTAGCAAGATCAACTTTCGGTAGCTTTATTAGTCACAAGTCAGGAAAAT
TTATGCATTACAAAATCGAAAATTTTTGTTACTTAATCTGGCAGACACCT
TCAAATTAGGAGTTTTTAAACGAACTTATGCTATATTTATGACCACTTGA
GCATGTATCGTTTTAAAATTTTTATGATTAATAAATATTTCAATTATTAA
AAA
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protein sequence of SMED30034525-orf-1

>SMED30034525-orf-1 ID=SMED30034525-orf-1|Name=SMED30034525-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=190bp
MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTG
RITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNEEIID
VEIIREDPDTTAEFRQFAIDVSHQASKDYKLEKDIAKSIKKKLDEEYNKI
WHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPSN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR037177DLC_sf
IPR001372Dynein_light_chain_typ-1/2
IPR002048EF_hand_dom
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
Vocabulary: cellular component
TermDefinition
GO:0030286dynein complex
GO:0005737cytoplasm
GO:0005856cytoskeleton
GO:0005874microtubule
GO:0005875microtubule associated complex
Vocabulary: biological process
TermDefinition
GO:0007017microtubule-based process
GO:0006810transport
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
GO:0003774motor activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001372Dynein light chain, type 1/2SMARTSM01375Dynein_light_2coord: 91..186
e-value: 3.6E-19
score: 79.7
IPR001372Dynein light chain, type 1/2PFAMPF01221Dynein_lightcoord: 109..186
e-value: 4.6E-20
score: 71.7
IPR001372Dynein light chain, type 1/2PANTHERPTHR11886DYNEIN LIGHT CHAINcoord: 106..186
IPR002048EF-hand domainSMARTSM00054efh_1coord: 36..64
e-value: 0.0036
score: 26.5
coord: 2..30
e-value: 0.015
score: 24.5
IPR002048EF-hand domainPFAMPF13499EF-hand_7coord: 3..60
e-value: 2.0E-8
score: 34.5
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 1..33
score: 12.003
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 37..67
score: 9.966
IPR002048EF-hand domainCDDcd00051EFhcoord: 2..61
e-value: 2.19421E-10
score: 52.1649
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 1..69
e-value: 1.4E-12
score: 49.2
NoneNo IPR availablePANTHERPTHR11886:SF78DYNEIN LIGHT CHAIN-RELATEDcoord: 106..186
IPR037177Dynein light chain superfamilyGENE3DG3DSA:3.30.740.10coord: 98..186
e-value: 3.1E-21
score: 77.3
IPR037177Dynein light chain superfamilySUPERFAMILYSSF54648DLCcoord: 100..187
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 45..57
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 2..70