GTP-binding protein Di-Ras2

Overview
NameGTP-binding protein Di-Ras2
Smed IDSMED30034513
Length (bp)958
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of GTP-binding protein Di-Ras2 (SMED30034513) t-SNE clustered cells

Violin plots show distribution of expression levels for GTP-binding protein Di-Ras2 (SMED30034513) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of GTP-binding protein Di-Ras2 (SMED30034513) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for GTP-binding protein Di-Ras2 (SMED30034513) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30034513

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30034513h1SMcG0006476 dd_Smed_v4_14502_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30034513h1SMcG0006476 dd_Smed_v4_14502_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30034513h1SMcG0006476 dd_Smed_v4_14502_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30034513h1SMcG0006476 dd_Smed_v6_14502_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Match: DIRAS2 (DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323])

HSP 1 Score: 199.519 bits (506), Expect = 6.770e-63
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Match: DIRAS1 (DIRAS family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:19127])

HSP 1 Score: 184.111 bits (466), Expect = 7.116e-57
Identity = 94/164 (57.32%), Postives = 123/164 (75.00%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PTIED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LV+S+ S  +L EL  IY+ I V  K ++ ++P+ML GNK D T  REV   E + VA EW C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLI-VQIKGSVEDIPVMLVGNKCDETQ-REVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLE 168          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Match: DIRAS1 (DIRAS family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:19127])

HSP 1 Score: 184.111 bits (466), Expect = 7.116e-57
Identity = 94/164 (57.32%), Postives = 123/164 (75.00%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PTIED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LV+S+ S  +L EL  IY+ I V  K ++ ++P+ML GNK D T  REV   E + VA EW C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLI-VQIKGSVEDIPVMLVGNKCDETQ-REVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLE 168          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Match: RAP1B (RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857])

HSP 1 Score: 141.739 bits (356), Expect = 1.073e-40
Identity = 68/163 (41.72%), Postives = 109/163 (66.87%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Match: RAP1B (RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857])

HSP 1 Score: 141.739 bits (356), Expect = 1.073e-40
Identity = 68/163 (41.72%), Postives = 109/163 (66.87%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: drn-1 (GTP-binding protein drn-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09930])

HSP 1 Score: 196.052 bits (497), Expect = 9.973e-62
Identity = 95/166 (57.23%), Postives = 121/166 (72.89%), Query Frame = 3
Query:  234 SDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYN-KQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            SDY++ +FGA  VGK+S+ +RF+KGTF++ YVPTIED YRQVIS N K + TLQI DT+GSHQFPAM +LSI  GNAF+L+YS+ +  +  EL  I E +K  K + I E PIML GNK D    REVS   G+KVA    CGFIETSAK+N NI ++FQ+LL ++
Sbjct:   29 SDYRVAVFGAGGVGKSSITQRFVKGTFNENYVPTIEDTYRQVISCNQKNVCTLQITDTTGSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVPIIEMMKEVKGNAIAETPIMLVGNKKDEESKREVSSNSGQKVATNMECGFIETSAKNNENITELFQQLLALE 194          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: rap-1 (Ras-related protein Rap-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18246])

HSP 1 Score: 138.272 bits (347), Expect = 9.061e-40
Identity = 74/196 (37.76%), Postives = 118/196 (60.20%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKC 824
            +YKIV+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ + I   K  + +EVP++L GNK DL D R V  ++G+ +A ++   F+ETSAK   N+ ++F +L++   N  +    R Q             G+ NK+C
Sbjct:    3 EYKIVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLMDLRDQILRVK--DTDEVPMILVGNKCDLEDERVVGKDQGQNLARQFGSAFLETSAKAKINVSEVFYDLVR-QINRRYPESGRRQ-------------GQSNKQC 182          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: rap-2 (RAP homolog (Vertebrate Rap GTPase family) [Source:UniProtKB/TrEMBL;Acc:O17599])

HSP 1 Score: 121.324 bits (303), Expect = 2.743e-33
Identity = 63/149 (42.28%), Postives = 92/149 (61.74%), Query Frame = 3
Query:  276 KTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            K++L  +F+  TF + Y PTIED YR+ I  + Q   L+I+DT+G+ QF +M  L I+ G  FV+VYSI S    +++  + E I   K S    VPI+L GNK DL+  R+V  EEG  +A+ W+C F E SAK+N N+   F E+++
Sbjct:   16 KSALTVQFVSSTFIEKYDPTIEDFYRKEIEVDGQPSVLEILDTAGTEQFSSMRDLYIKNGQGFVVVYSITSQQTFHDIRNMKEQIVRVKGS--ENVPILLVGNKCDLSHQRQVRSEEGLALAESWSCPFTECSAKNNQNVNVTFAEIVR 162          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: rap-3 (RAP homolog (Vertebrate Rap GTPase family) [Source:UniProtKB/TrEMBL;Acc:O01312])

HSP 1 Score: 114.005 bits (284), Expect = 2.823e-30
Identity = 68/196 (34.69%), Postives = 106/196 (54.08%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKC 824
            +YKIV+ G   VGK++L  ++++G F   Y  TIED+YR++   + +   L+I+DT+G+ QF  M +    T   FVLV+S+   S    L + + DI   +     EVP++L GNKSDL + R+V   E    A++    + ETSA+ N N+ ++F+E     C  L   + +S   N   R  S  S   +KKC
Sbjct:    3 EYKIVVLGNGGVGKSALTLQYVQGIFVHTYDATIEDSYRKLSKVDAENARLEILDTAGTEQFTGMRETYYRTAQGFVLVFSLAETSTFENLKQTFTDIIAIRG---KEVPMILVGNKSDLAETRQVDESEAHNFAEKLKIPYFETSARLNQNVSEVFEE-----CAVL---IQKSAKPNIERRKWSSESEIGDKKC 187          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: ssr-2 (Sperm-Specific family, class R [Source:UniProtKB/TrEMBL;Acc:O02139])

HSP 1 Score: 111.694 bits (278), Expect = 2.736e-28
Identity = 59/164 (35.98%), Postives = 106/164 (64.63%), Query Frame = 3
Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW--NCGFIETSAKDNTNIKDMFQELLQM 725
            Y++V+ G++KVGKT++I+R++   FS  Y  TIED + +          L I+DT  +  FP M +LSI + +AF+LV+S+   ++  E+++I+++I  S++S++NE+PI++ GNK D+ + +++  E  K   +    +  +IE SAKDN  I D+F+ LL++
Sbjct:    6 YRLVVLGSAKVGKTNIIRRYLYNEFSSKYKETIEDLHSREFRIQGVPLPLDILDT--NFNFPDMRRLSIASASAFLLVFSVDDVTSFKEMSDIWQEI-CSRRSDLNELPIVVVGNKCDVEN-KKIYEETAKAFTNRLSSDVRYIEVSAKDNIRITDVFRTLLEL 165          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: CG8500 (gene:FBgn0037754 transcript:FBtr0082139)

HSP 1 Score: 180.644 bits (457), Expect = 2.164e-55
Identity = 96/165 (58.18%), Postives = 122/165 (73.94%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLT-DCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RFIKGTF + Y+PTIED YRQVIS NK I TLQI DT+GSHQFPAM +LSI  G+AF+LVYS+ S  +L EL  I+  IK  K ++I  +P+ML GNK D T + REVS  EG+  A  W+  F+ETSAK N N+ ++FQELL M+
Sbjct:   18 DYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELREVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNME 182          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: CG8500 (gene:FBgn0037754 transcript:FBtr0347364)

HSP 1 Score: 180.644 bits (457), Expect = 2.164e-55
Identity = 96/165 (58.18%), Postives = 122/165 (73.94%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLT-DCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RFIKGTF + Y+PTIED YRQVIS NK I TLQI DT+GSHQFPAM +LSI  G+AF+LVYS+ S  +L EL  I+  IK  K ++I  +P+ML GNK D T + REVS  EG+  A  W+  F+ETSAK N N+ ++FQELL M+
Sbjct:   18 DYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELREVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNME 182          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0303154)

HSP 1 Score: 141.739 bits (356), Expect = 5.480e-41
Identity = 70/162 (43.21%), Postives = 108/162 (66.67%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YKIV+ G+  VGK++L  +F++  F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ E I   K +  ++VP++L GNK DL + R V  E GK +A ++NC F+ETSAK   N+ D+F +L++
Sbjct:    3 EYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDT--DDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAKAKVNVNDIFYDLVR 162          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0072867)

HSP 1 Score: 141.739 bits (356), Expect = 5.480e-41
Identity = 70/162 (43.21%), Postives = 108/162 (66.67%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YKIV+ G+  VGK++L  +F++  F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ E I   K +  ++VP++L GNK DL + R V  E GK +A ++NC F+ETSAK   N+ D+F +L++
Sbjct:    3 EYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDT--DDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAKAKVNVNDIFYDLVR 162          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0332671)

HSP 1 Score: 141.739 bits (356), Expect = 5.480e-41
Identity = 70/162 (43.21%), Postives = 108/162 (66.67%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YKIV+ G+  VGK++L  +F++  F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ E I   K +  ++VP++L GNK DL + R V  E GK +A ++NC F+ETSAK   N+ D+F +L++
Sbjct:    3 EYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDT--DDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAKAKVNVNDIFYDLVR 162          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Match: diras1a (DIRAS family, GTP-binding RAS-like 1a [Source:ZFIN;Acc:ZDB-GENE-030131-5788])

HSP 1 Score: 192.2 bits (487), Expect = 2.212e-60
Identity = 102/199 (51.26%), Postives = 137/199 (68.84%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKCDIV 833
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED YRQVIS +K + TL+I DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +PIML GNKSD T  REV  +EG+  A+ W C F+ETSAK NTN+K++FQELL +D     +   RS    +        + KL  KC ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLEITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYQQV-LAIKGNVENIPIMLVGNKSDETQ-REVETKEGEAQANTWKCAFMETSAKTNTNVKELFQELLNLDKKRDMSLNMRSSKQRR--------ADKLKAKCSVM 195          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Match: diras1b (DIRAS family, GTP-binding RAS-like 1b [Source:ZFIN;Acc:ZDB-GENE-070912-620])

HSP 1 Score: 184.111 bits (466), Expect = 3.849e-57
Identity = 94/164 (57.32%), Postives = 123/164 (75.00%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ I ++ K N+  +PIML GNKSD T  REV  E+G+  +  W C F+ETSAK N N+ ++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSKQSLEELKPIYQQI-LAIKGNVENIPIMLVGNKSDETQ-REVKTEDGEAQSKTWKCAFMETSAKTNHNVTELFQELLNLE 168          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Match: rap1b (RAP1B, member of RAS oncogene family [Source:NCBI gene;Acc:321107])

HSP 1 Score: 142.124 bits (357), Expect = 5.690e-41
Identity = 68/163 (41.72%), Postives = 109/163 (66.87%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWN-CGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +WN C F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKAMEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNSCAFLESSAKSKINVNEIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Match: rap1ab (RAP1A, member of RAS oncogene family b [Source:ZFIN;Acc:ZDB-GENE-040426-2738])

HSP 1 Score: 141.739 bits (356), Expect = 6.314e-41
Identity = 69/163 (42.33%), Postives = 108/163 (66.26%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ D+F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Match: rap1ab (RAP1A, member of RAS oncogene family b [Source:ZFIN;Acc:ZDB-GENE-040426-2738])

HSP 1 Score: 141.739 bits (356), Expect = 6.314e-41
Identity = 69/163 (42.33%), Postives = 108/163 (66.26%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ D+F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: pnp (purine nucleoside phosphorylase [Source:Xenbase;Acc:XB-GENE-1011598])

HSP 1 Score: 201.83 bits (512), Expect = 7.664e-64
Identity = 94/168 (55.95%), Postives = 127/168 (75.60%), Query Frame = 3
Query:  225 DPQSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            +P +DY++V+FGA+ VGK+SL+ RF++GTF + Y+PTIED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYS+ S  ++ EL  IYE I    K +   +PIML GNKSD T  REV   EG+ +A++W C F+ETSAK N N++++FQELL ++
Sbjct:    3 EPSNDYRVVVFGAAGVGKSSLVLRFVRGTFRETYIPTIEDTYRQVISCDKNICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSVTSKQSMEELQPIYEQI-CQIKGDTQNIPIMLVGNKSDET-LREVQASEGECLANKWKCSFMETSAKLNYNVQELFQELLNLE 168          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: DIRAS2 (DIRAS family GTP binding RAS like 2 [Source:NCBI gene;Acc:100038204])

HSP 1 Score: 186.037 bits (471), Expect = 9.508e-58
Identity = 95/164 (57.93%), Postives = 123/164 (75.00%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF + Y+PTIED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNKSD +  RE+   EG+ +A +W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRESYIPTIEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CQIKGDVESIPIMLVGNKSDESQNRELDSSEGEAMAKKWKCAFMETSAKMNHNVKELFQELLNLE 169          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: diras1 (DIRAS family GTP binding RAS like 1 [Source:NCBI gene;Acc:780240])

HSP 1 Score: 180.259 bits (456), Expect = 1.722e-55
Identity = 92/164 (56.10%), Postives = 123/164 (75.00%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PTIED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LV+S+ S  ++ EL  IY+ I +  K +I  +P+ML GNK D T  REV  +E + +A EW C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVPRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSIEELKPIYQQI-LQIKGSIENIPVMLVGNKCDETQ-REVDTKEVEALAKEWKCAFMETSAKMNYNVKELFQELLNLE 168          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: rap1b (RAP1B, member of RAS oncogene family [Source:NCBI gene;Acc:493557])

HSP 1 Score: 141.354 bits (355), Expect = 1.460e-40
Identity = 68/163 (41.72%), Postives = 109/163 (66.87%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: aldh1a3 (aldehyde dehydrogenase 1 family member A3 [Source:Xenbase;Acc:XB-GENE-992885])

HSP 1 Score: 140.198 bits (352), Expect = 4.377e-40
Identity = 68/163 (41.72%), Postives = 107/163 (65.64%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +    Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVEGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Diras2 (DIRAS family, GTP-binding RAS-like 2 [Source:MGI Symbol;Acc:MGI:1915453])

HSP 1 Score: 198.364 bits (503), Expect = 1.273e-62
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Diras1 (DIRAS family, GTP-binding RAS-like 1 [Source:MGI Symbol;Acc:MGI:2183442])

HSP 1 Score: 186.037 bits (471), Expect = 8.297e-58
Identity = 95/164 (57.93%), Postives = 125/164 (76.22%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PTIED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LV+S+ S  +L+EL+ IY+ I V  K ++ ++PIML GNK D T  REV   E + VA EW C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLDELSPIYKLI-VQIKGSVEDIPIMLVGNKCDETQ-REVHTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLE 168          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Rap1b (RAS related protein 1b [Source:MGI Symbol;Acc:MGI:894315])

HSP 1 Score: 141.739 bits (356), Expect = 7.364e-41
Identity = 68/163 (41.72%), Postives = 109/163 (66.87%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Rap1a (RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852])

HSP 1 Score: 140.198 bits (352), Expect = 3.254e-40
Identity = 68/163 (41.72%), Postives = 108/163 (66.26%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Rasd2 (RASD family, member 2 [Source:MGI Symbol;Acc:MGI:1922391])

HSP 1 Score: 142.124 bits (357), Expect = 4.897e-40
Identity = 71/173 (41.04%), Postives = 113/173 (65.32%), Query Frame = 3
Query:  231 QSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNIN------EVPIMLAGNKSDLTD-CREVSFEEGK-KVADEWNCGFIETSAKDNTNIKDMFQELLQM 725
            ++ Y++V+ GAS+VGK+S++ RF+ G F D Y PTIED +R+V + +  ++ L I+DTSG+H FPAM +LSI TG+ F+LV+S+ S  + +E+  + + I   K    N      E+P+++ GNK+D ++ CR+V   E +  V+ + NC + E SAK NTN+ +MF  L  M
Sbjct:   17 KNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIHGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHSELCRQVPAMEAELLVSGDENCAYFEVSAKKNTNVNEMFYVLFSM 189          
BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q96HU8|DIRA2_HUMAN (GTP-binding protein Di-Ras2 OS=Homo sapiens OX=9606 GN=DIRAS2 PE=1 SV=1)

HSP 1 Score: 199.519 bits (506), Expect = 3.251e-62
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169          
BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q95KD9|DIRA2_MACFA (GTP-binding protein Di-Ras2 OS=Macaca fascicularis OX=9541 GN=DIRAS2 PE=2 SV=1)

HSP 1 Score: 198.749 bits (504), Expect = 5.650e-62
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDMESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169          
BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q5PR73|DIRA2_MOUSE (GTP-binding protein Di-Ras2 OS=Mus musculus OX=10090 GN=Diras2 PE=1 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 8.906e-62
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169          
BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q5R6S2|DIRA2_PONAB (GTP-binding protein Di-Ras2 OS=Pongo abelii OX=9601 GN=DIRAS2 PE=2 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 1.389e-61
Identity = 91/164 (55.49%), Postives = 119/164 (72.56%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YR+VIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRRVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169          
BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q09930|DIRA_CAEEL (GTP-binding protein drn-1 (Fragment) OS=Caenorhabditis elegans OX=6239 GN=drn-1 PE=1 SV=3)

HSP 1 Score: 196.052 bits (497), Expect = 1.269e-60
Identity = 95/166 (57.23%), Postives = 121/166 (72.89%), Query Frame = 3
Query:  234 SDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYN-KQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            SDY++ +FGA  VGK+S+ +RF+KGTF++ YVPTIED YRQVIS N K + TLQI DT+GSHQFPAM +LSI  GNAF+L+YS+ +  +  EL  I E +K  K + I E PIML GNK D    REVS   G+KVA    CGFIETSAK+N NI ++FQ+LL ++
Sbjct:   29 SDYRVAVFGAGGVGKSSITQRFVKGTFNENYVPTIEDTYRQVISCNQKNVCTLQITDTTGSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVPIIEMMKEVKGNAIAETPIMLVGNKKDEESKREVSSNSGQKVATNMECGFIETSAKNNENITELFQQLLALE 194          
BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: A0A0R3SBV7 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS2003 PE=4 SV=1)

HSP 1 Score: 221.476 bits (563), Expect = 4.191e-68
Identity = 106/203 (52.22%), Postives = 150/203 (73.89%), Query Frame = 3
Query:  234 SDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYED-IKVSKKSNINEVPIMLAGNKSDLTD-CREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH---LFATLNRSQTANKSFRLLSHTSGKLNKKCD 827
            SDY++ +FGAS VGK+SL+ RF+KGTF + YVPTIED +RQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+L+YSI + ++L+EL  IYE+ +++  ++ +  +PIML GNKSD  +  REV   +G+++A +WNCGF+ETSAK+N N+K++FQELL+M+      L    + S++  K FR L H S + + K D
Sbjct:    6 SDYRVAVFGASGVGKSSLVLRFVKGTFREAYVPTIEDTFRQVISCNKQVCTLQITDTTGSHQFPAMQRLSISRGHAFMLIYSITNRASLDELTPIYEELVRIKGQAAMQSIPIMLVGNKSDEDESSREVPTNQGEELAQKWNCGFMETSAKNNLNVKEVFQELLRMETRQNMTLVGDNSDSKSFLKCFRFLRHGSARRSPKND 208          
BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: A0A087VXX6 (GTP binding protein Di Ras2 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000080400 PE=4 SV=1)

HSP 1 Score: 218.009 bits (554), Expect = 9.548e-67
Identity = 104/194 (53.61%), Postives = 141/194 (72.68%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYED-IKVSKKSNINEVPIMLAGNKSDLTDC-REVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH---LFATLNRSQTANKSFRLLSHTS 803
            DY++ +FGAS VGK+SL+ RF+KGTF + Y+PTIED +RQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+L+YS+ S  +L+EL  IYE+ +++   + +  +PIML GNKSD  D  REVS  +G+ VA +WNCGF+ETSAK+N N+K++FQELL+M+      L    + S+     FR L H S
Sbjct:    7 DYRVAVFGASGVGKSSLVLRFVKGTFREAYIPTIEDTFRQVISCNKQVCTLQITDTTGSHQFPAMQRLSISRGHAFMLIYSVTSRVSLDELTPIYEELVRIKGPTAMQSIPIMLVGNKSDEGDTGREVSTIQGEAVAQKWNCGFMETSAKNNVNVKEVFQELLRMETRQNMTLVGDTSDSKGILSCFRFLRHES 200          
BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: A0A0R3WE68 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS9099 PE=4 SV=1)

HSP 1 Score: 217.624 bits (553), Expect = 1.507e-66
Identity = 107/205 (52.20%), Postives = 146/205 (71.22%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYED-IKVSKKSNINEVPIMLAGNKSDLTDC-REVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH---LFATLNRSQTANKSFRLLSHTS---GKLNKKCD 827
            DY++ +FGAS VGK+SL+ RF+KGTF + Y+PTIED +RQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+L+YSI S  +L+EL  IYE+ +++   + +  +PIML GNKSD +D  REVS  +G+ +A +WNCGF+ETSAK+N N+K++FQELL+M+      L    + S+     FR L H S   G   +K D
Sbjct:    7 DYRVAVFGASGVGKSSLVLRFVKGTFREAYIPTIEDTFRQVISCNKQVCTLQITDTTGSHQFPAMQRLSISRGHAFMLIYSITSRVSLDELTPIYEELVRIKGPAAMPSIPIMLVGNKSDESDTGREVSTVQGEAMAQKWNCGFMETSAKNNVNVKEVFQELLRMETRQNMTLVGDNSDSKGILSCFRFLRHGSTQRGSRGEKSD 211          
BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: W6US97 (GTP-binding protein Di-Ras2 OS=Echinococcus granulosus OX=6210 GN=EGR_00687 PE=4 SV=1)

HSP 1 Score: 218.009 bits (554), Expect = 2.625e-66
Identity = 104/194 (53.61%), Postives = 140/194 (72.16%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYED-IKVSKKSNINEVPIMLAGNKSDLTDC-REVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH---LFATLNRSQTANKSFRLLSHTS 803
            DY++ +FGAS VGK+SL+ RF+KGTF + Y+PTIED +RQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+L+YS+ S  +L+EL  IYE+ +++     +  +PIML GNKSD  D  REVS  +G+ VA +WNCGF+ETSAK+N N+K++FQELL+M+      L    + S+     FR L H S
Sbjct:   33 DYRVAVFGASGVGKSSLVLRFVKGTFREAYIPTIEDTFRQVISCNKQVCTLQITDTTGSHQFPAMQRLSISRGHAFMLIYSVTSRVSLDELTPIYEELVRIKGPRAMRSIPIMLVGNKSDEGDTGREVSTIQGEAVAQKWNCGFMETSAKNNVNVKEVFQELLRMETRQNMTLVGDTSDSKGILSCFRFLRHGS 226          
BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: G7YC89 (DIRAS family GTP-binding Ras-like 2 OS=Clonorchis sinensis OX=79923 GN=DIRAS2 PE=4 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 7.964e-66
Identity = 95/171 (55.56%), Postives = 128/171 (74.85%), Query Frame = 3
Query:  234 SDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFA 746
            +DY++ +FGA  VGKTSL+ RF++GTF + YVPTIED YRQVIS NKQ+ TLQI DT+GSHQFPAM +LS+  G+AF+LVYS+ + S+  EL  +Y ++ + K+  +  VPIML GNK D  + REVS   GK ++ +W CGF+ETSAK NTN+K++FQELL+M+     A
Sbjct:    6 TDYRVAVFGAGGVGKTSLVLRFVRGTFRETYVPTIEDTYRQVISCNKQVCTLQITDTTGSHQFPAMQRLSMSKGHAFILVYSVTNQSSFEELPHLYNELTIIKREELARVPIMLVGNKIDEGESREVSTALGKALSQKWKCGFMETSAKTNTNVKEVFQELLRMETRQNMA 176          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: diras1a (GTP-binding protein Di-Ras1-like [Source:NCBI gene;Acc:103039567])

HSP 1 Score: 186.422 bits (472), Expect = 3.453e-58
Identity = 100/199 (50.25%), Postives = 135/199 (67.84%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKCDIV 833
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED YRQVIS +K + TL+I DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +PIML GNKSD T  REV  +EG+  A+ W C F+ETSAK N N+ ++FQELL +D     +   RS    +        + KL  KC ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLEITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYQQV-LAIKGNVEGIPIMLVGNKSDETQ-REVETKEGEAQANNWKCAFMETSAKTNHNVTELFQELLNLDKKRDMSLNMRSSKQRR--------ADKLKAKCSVM 195          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: DIRAS2 (DIRAS family GTPase 2 [Source:NCBI gene;Acc:103025938])

HSP 1 Score: 182.956 bits (463), Expect = 8.619e-57
Identity = 93/164 (56.71%), Postives = 122/164 (74.39%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF + Y+PTIED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  I+E I    K ++  +PIML GNK+D T  REV   +G+ ++  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRESYIPTIEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSKQSLEELKPIFEQI-CQIKGDVESIPIMLVGNKNDETSGREVESSDGEALSKRWKCAFMETSAKTNHNVKELFQELLNLE 169          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: ENSAMXT00000054511.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000334.1:549901:552517:1 gene:ENSAMXG00000043039.1 transcript:ENSAMXT00000054511.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 162.155 bits (409), Expect = 2.200e-48
Identity = 88/202 (43.56%), Postives = 128/202 (63.37%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDM------FQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKC 824
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED Y+QVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +P+ML GNK+D T  REV  E+G+  A  W C F+ETS ++             + E    +  H + TL +++   ++   + H     + +C
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYQQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYQQM-LAIKGNVEGIPVMLVGNKNDETQ-REVQTEDGEAQAQAWKCAFMETSGQNQPQCHRALPGAAEYGEEALHEPEHRWKTLRKTKAHRQTEGEVQHYVEAEHAQC 206          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: ENSAMXT00000048672.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000334.1:542785:552517:1 gene:ENSAMXG00000043039.1 transcript:ENSAMXT00000048672.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 162.155 bits (409), Expect = 2.200e-48
Identity = 88/202 (43.56%), Postives = 128/202 (63.37%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDM------FQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKC 824
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED Y+QVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +P+ML GNK+D T  REV  E+G+  A  W C F+ETS ++             + E    +  H + TL +++   ++   + H     + +C
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYQQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYQQM-LAIKGNVEGIPVMLVGNKNDETQ-REVQTEDGEAQAQAWKCAFMETSGQNQPQCHRALPGAAEYGEEALHEPEHRWKTLRKTKAHRQTEGEVQHYVEAEHAQC 206          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: rap1ab (ras-related protein Rap-1A [Source:NCBI gene;Acc:103022868])

HSP 1 Score: 141.739 bits (356), Expect = 6.019e-41
Identity = 69/163 (42.33%), Postives = 108/163 (66.26%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWN-CGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +WN C F+E+SAK   N+ D+F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNHCAFLESSAKSKINVLDIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: DIRAS2 (DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323])

HSP 1 Score: 179.874 bits (455), Expect = 3.197e-56
Identity = 95/164 (57.93%), Postives = 120/164 (73.17%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF++GTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AFVLVYSI S  +L EL  IYE I  S K +   VPIML GNK D T  REV   EG+  A  W C F+ETSAK + N++++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVRGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISRGHAFVLVYSIASRQSLEELRPIYEVI-CSLKGDTEAVPIMLVGNKCDETT-REVQTAEGEAQAKAWRCAFMETSAKMDYNVRELFQELLNLE 168          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: DIRAS2 (DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323])

HSP 1 Score: 175.637 bits (444), Expect = 1.440e-54
Identity = 90/168 (53.57%), Postives = 120/168 (71.43%), Query Frame = 3
Query:  225 DPQSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            +P SDY +V+FGA  VGK+SL+ RF++GTF + YVPT+ED YRQVIS +K + TLQI DT+GSHQFPAM +L+I  G+AF+LVYS+ S  +L EL  IY D+    K +++ VP+ML  NK D T  REV+  EG+  A  W C F ETSAK + N+ + FQELL ++
Sbjct:    3 EPSSDYHVVVFGAGGVGKSSLVLRFVRGTFREAYVPTVEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLAISRGHAFLLVYSVTSRQSLEELRPIY-DVIAQIKGDVSAVPMMLVANKCDET-AREVAAGEGETQAKAWRCAFTETSAKMDYNVSEAFQELLTLE 168          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: RIT2 (Ras like without CAAX 2 [Source:HGNC Symbol;Acc:HGNC:10017])

HSP 1 Score: 116.701 bits (291), Expect = 1.272e-31
Identity = 62/180 (34.44%), Postives = 104/180 (57.78%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMF----QELLQMDCNHLFATLNRSQ 764
            +YKIV+ G   VGK+++  +FI   F + + PTIEDAY+  +  + +   L I+DT+G  +F AM    +  G  F++ YSI    +  E A+  + I   +  +  EVP++L GNK+DL + R+VS EEG+ +A E++C F ETSA     + ++F    +E+ + + + + A   RS+
Sbjct:   20 EYKIVMLGPGGVGKSAMTMQFISHRFPEDHDPTIEDAYKTQVRIDDETAHLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFQEAAQFKQLIYQVR--HTYEVPVVLVGNKTDLGEIRQVSQEEGRSLAREFSCQFFETSAALRQYVDEVFYAVVREIRRKEHDAMVAMERRSK 197          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: rheb (Ras homolog, mTORC1 binding [Source:ZFIN;Acc:ZDB-GENE-040426-1690])

HSP 1 Score: 110.153 bits (274), Expect = 1.322e-29
Identity = 62/169 (36.69%), Postives = 101/169 (59.76%), Query Frame = 3
Query:  228 PQSDY-KIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQ---FPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            PQ  Y KI + G   VGK+SL  +F++G F D Y PTIE+ + + ++ N Q F L+++DT+G  +   FP  + + I   + +VLVYS+ S  +   +  I+E  K+        VP++L GNK DL   R +S EEGK +A  WN  F+E++AK++  + ++F+ ++Q
Sbjct:    2 PQPKYRKIAVLGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKNLTVNGQEFNLKLVDTAGQDEYSMFPQTYSMDI---HGYVLVYSVTSIKSFEVVRVIHE--KLLDMVGKVHVPLVLVGNKKDLHMERVISCEEGKTLATSWNAAFMESTAKEHQTVVEVFKWMIQ 165          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001560.1 (pep scaffold:Pmarinus_7.0:GL476528:157506:173211:1 gene:ENSPMAG00000001407.1 transcript:ENSPMAT00000001560.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 108.997 bits (271), Expect = 8.945e-29
Identity = 49/161 (30.43%), Postives = 92/161 (57.14%), Query Frame = 3
Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +K+++ G+  VGK++L  +F+   F + Y PT  D+YR+ +  + +   + I+DT+G   + A+      +G  F+  +SI  H +     ++    ++ +    + +P +L GNKSDL + R+VS EE +  AD+W  G++ETSAK   N+  +F +L++
Sbjct:   15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCAFSICEHESFAGTTDLRRSEQILRVKEDDSIPFLLVGNKSDLEERRQVSIEEARARADQWGVGYVETSAKTRANVDKVFFDLMR 175          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: RSR1 (GTP-binding protein of the Ras superfamily; required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases [Source:SGD;Acc:S000003384])

HSP 1 Score: 138.658 bits (348), Expect = 1.103e-39
Identity = 70/163 (42.94%), Postives = 109/163 (66.87%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWN-CGFIETSAKDNTNIKDMFQELLQ 722
            DYK+V+ GA  VGK+ L  +F++G + D Y PTIED+YR+ I  + ++F L+I+DT+G  QF AM +L I++G  F+LVYS+    +L EL E+ E +   K S  + VP++L GNK+DL + R +S EEG +V+ +W    F ETSA   +N+ ++F +L++
Sbjct:    3 DYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDS--DRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRSNVDEVFVDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: RAS1 (GTPase involved in G-protein signaling in adenylate cyclase activation; plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes; relative distribution to the nucleus increases upon DNA replication stress; RAS1 has a paralog, RAS2, that arose from the whole genome duplication [Source:SGD;Acc:S000005627])

HSP 1 Score: 121.709 bits (304), Expect = 6.703e-33
Identity = 67/176 (38.07%), Postives = 113/176 (64.20%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQM--DCNHLFATLNR 758
            +YKIV+ G   VGK++L  +FI+  F D Y PTIED+YR+ +  + ++  L I+DT+G  ++ AM +  + TG  F+LVYS+ S ++ +EL   Y+ I+  K S+   +P+++ GNK DL + R+VS+E+G ++A + N  F+ETSAK   N+ + F  L+++  D    + ++NR
Sbjct:   10 EYKIVVVGGGGVGKSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSILDILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDY--IPVVVVGNKLDLENERQVSYEDGLRLAKQLNAPFLETSAKQAINVDEAFYSLIRLVRDDGGKYNSMNR 183          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: RAS2 (GTP-binding protein; regulates nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes; RAS2 has a paralog, RAS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005042])

HSP 1 Score: 112.849 bits (281), Expect = 2.043e-29
Identity = 63/163 (38.65%), Postives = 104/163 (63.80%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQM 725
            +YK+V+ G   VGK++L  +  +  F D Y PTIED+YR+ +  + ++  L I+DT+G  ++ AM +  +  G  F+LVYSI S S+L+EL   Y+ I   K ++   VPI++ GNKSDL + ++VS+++G  +A + N  F+ETSAK   N+++ F  L ++
Sbjct:   10 EYKLVVVGGGGVGKSALTIQLTQSHFVDEYDPTIEDSYRKQVVIDDEVSILDILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQILRVKDTDY--VPIVVVGNKSDLENEKQVSYQDGLNMAKQMNAPFLETSAKQAINVEEAFYTLARL 170          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: YPT6 (Rab family GTPase; required for endosome-to-Golgii, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6 [Source:SGD;Acc:S000004252])

HSP 1 Score: 88.5817 bits (218), Expect = 2.305e-21
Identity = 58/161 (36.02%), Postives = 90/161 (55.90%), Query Frame = 3
Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIE-DAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCG-FIETSAKDNTNIKDMFQEL 716
            YKIV  G   VGKTSLI RF+  TF D Y  TI  D   + +  + +   LQ+ DT+G  +F ++    I      ++VY I    +   + +  ED+K +++ + N V + + GNKSDL+D R++S EEG+K A       F+ETS K   N+K +F+++
Sbjct:   11 YKIVFLGEQGVGKTSLITRFMYDTFDDHYQATIGIDFLSKTMYLDDKTIRLQLWDTAGQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYIDKWIEDVK-NERGDEN-VILCIVGNKSDLSDERQISTEEGEKKAKLLGAKIFMETSTKAGYNVKALFKKI 169          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: RHB1 (Putative Rheb-related GTPase; involved in regulating canavanine resistance and arginine uptake; member of the Ras superfamily of G-proteins [Source:SGD;Acc:S000000622])

HSP 1 Score: 85.5001 bits (210), Expect = 2.501e-20
Identity = 57/175 (32.57%), Postives = 98/175 (56.00%), Query Frame = 3
Query:  243 KIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDC-----REVSFEEGKKVA------DEWN-CGFIETSAKDNTNIKDMFQELL-QMD 728
            KI L GA  VGKT+L  RF++  F + Y PTIE+ + ++I Y     TL+I+DT+G  +   ++  S+      +L YSI + ++ + +  +++  K+  +   + +P++L G K+DL        R V+  EG+K+A      D+ N   FIE SA+ + N+++ F  LL QM+
Sbjct:   18 KIALIGARNVGKTTLTVRFVESRFVESYYPTIENEFTRIIPYKSHDCTLEILDTAGQDEVSLLNIKSLTGVRGIILCYSIINRASFDLIPILWD--KLVDQLGKDNLPVILVGTKADLGRSTKGVKRCVTKAEGEKLASTIGSQDKRNQAAFIECSAELDYNVEETFMLLLKQME 190          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO30327 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T133])

HSP 1 Score: 139.043 bits (349), Expect = 4.284e-40
Identity = 74/178 (41.57%), Postives = 109/178 (61.24%), Query Frame = 3
Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVS----------FEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQM--DCNH 737
            ++I +FG + VGKTS++KRF  G FS+ Y PT+ED Y +V++ N  I  L   D+SGS+QFPAM +++I+  + F+LVYS+ S  +  EL  +  ++   KKS   ++P++L GNK DL + REVS          F   K    + N   +ETSAKD+ NI D+F E++ M  DC H
Sbjct:    9 HEIAVFGGAGVGKTSIVKRFYCGKFSEEYEPTVEDCYSKVLNKNGSIMVLNTTDSSGSYQFPAMREVAIKRASGFILVYSLDSKFSFEELKRLLYEVIEKKKS--ADIPVVLVGNKKDLEEQREVSSEQVVKEVMAFAREKGCEGKLNMRQVETSAKDDCNISDVFDEVVDMLEDCTH 184          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO39047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB93])

HSP 1 Score: 137.502 bits (345), Expect = 8.245e-40
Identity = 68/163 (41.72%), Postives = 110/163 (67.48%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  ++G+ +A ++ NC F+ETSAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVK--DTDDVPMVLVGNKCDLEDERVVGKDQGQNLAKQFANCTFLETSAKAKINVNEIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO33484 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS29])

HSP 1 Score: 134.806 bits (338), Expect = 1.303e-38
Identity = 72/176 (40.91%), Postives = 107/176 (60.80%), Query Frame = 3
Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVS----------FEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH 737
            ++I +FG + VGKTS++KRF  G FS+ Y PT+ED Y +V++ N  I  L   D+SGS+QFPAM +++I+  + F+LVYS+ S  +  EL  +  ++   KKS   ++P++L GNK DL + REVS          F   K    + N   +ETSAKD+ NI D+F E++ M   H
Sbjct:    9 HEIAVFGGAGVGKTSIVKRFYCGKFSEEYEPTVEDCYSKVLNKNGSIMVLNTTDSSGSYQFPAMREVAIKRASGFILVYSLDSKFSFEELKRLLYEVIEKKKS--ADIPVVLVGNKKDLEEQREVSSEQVVKEVMAFAREKGCEGKLNMRQVETSAKDDCNISDVFDEVVDMLDKH 182          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO36578 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI58])

HSP 1 Score: 120.168 bits (300), Expect = 2.993e-33
Identity = 69/167 (41.32%), Postives = 97/167 (58.08%), Query Frame = 3
Query:  246 IVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSD---------LTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELL 719
            IV FGAS VGKTSLI RF+   F+D Y PTIED + + + +N + + LQIIDTSG+++FPAM K+ I  G+AFVLVYS     +  +L     +I    K   N  P ++  NK+D         LTD R +       V  EW   +I+ SAK+N+ ++D+F  L+
Sbjct:    1 IVFFGASSVGKTSLILRFLGYAFNDDYSPTIEDFFIKHVFFNNETYELQIIDTSGTYEFPAMRKVDIAKGDAFVLVYSQDHPESFTKLNRYRSEILEGGK---NRHPCIVVCNKNDLPLATHLGVLTDHRGLRISAQHLVQTEWQSLWIDCSAKENSQVEDIFLRLM 164          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO27138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI58])

HSP 1 Score: 120.168 bits (300), Expect = 2.993e-33
Identity = 69/167 (41.32%), Postives = 97/167 (58.08%), Query Frame = 3
Query:  246 IVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSD---------LTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELL 719
            IV FGAS VGKTSLI RF+   F+D Y PTIED + + + +N + + LQIIDTSG+++FPAM K+ I  G+AFVLVYS     +  +L     +I    K   N  P ++  NK+D         LTD R +       V  EW   +I+ SAK+N+ ++D+F  L+
Sbjct:    1 IVFFGASSVGKTSLILRFLGYAFNDDYSPTIEDFFIKHVFFNNETYELQIIDTSGTYEFPAMRKVDIAKGDAFVLVYSQDHPESFTKLNRYRSEILEGGK---NRHPCIVVCNKNDLPLATHLGVLTDHRGLRISAQHLVQTEWQSLWIDCSAKENSQVEDIFLRLM 164          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: diras1b (GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:101171042])

HSP 1 Score: 186.808 bits (473), Expect = 2.697e-58
Identity = 94/164 (57.32%), Postives = 125/164 (76.22%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +PIML GNKSD T  REV  ++G+  A++W C F+ETSAK N N+ ++FQELL +D
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSKQSLEELKPIYQQV-LAIKGNVEAIPIMLVGNKSDETQ-REVETKDGEAQANQWKCAFMETSAKTNHNVTELFQELLNLD 168          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: ENSORLT00000038069.1 (GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:101164795])

HSP 1 Score: 184.882 bits (468), Expect = 1.693e-57
Identity = 93/164 (56.71%), Postives = 123/164 (75.00%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED Y QVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  ++ EL  IY+ I ++ K ++  +PIML GNKSD T  REV  +EG+  A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYTQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSIEELKPIYQQI-LAIKGSVESIPIMLVGNKSDETAQREVESKEGEAQATAWKCAFMETSAKTNFNVKELFQELLALE 169          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: ENSORLT00000037992.1 (GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:101164795])

HSP 1 Score: 184.882 bits (468), Expect = 1.693e-57
Identity = 93/164 (56.71%), Postives = 123/164 (75.00%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED Y QVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  ++ EL  IY+ I ++ K ++  +PIML GNKSD T  REV  +EG+  A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYTQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSIEELKPIYQQI-LAIKGSVESIPIMLVGNKSDETAQREVESKEGEAQATAWKCAFMETSAKTNFNVKELFQELLALE 169          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: rap1aa (ras-related protein O-Krev [Source:NCBI gene;Acc:101171247])

HSP 1 Score: 142.124 bits (357), Expect = 4.399e-41
Identity = 69/163 (42.33%), Postives = 108/163 (66.26%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  +  +VP++L GNK DL D R V  E+G+ +A +W NC F+ETSAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEIDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLETSAKSKINVNEIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: rap1ab (ras-related protein Rap-1A [Source:NCBI gene;Acc:101167529])

HSP 1 Score: 141.739 bits (356), Expect = 5.318e-41
Identity = 69/163 (42.33%), Postives = 108/163 (66.26%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ D+F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVR 163          
BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000080856.1 (SMESG000080856.1)

HSP 1 Score: 194.126 bits (492), Expect = 3.427e-61
Identity = 96/165 (58.18%), Postives = 130/165 (78.79%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIK-VSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FG+  VGK+S++ RF++GTF + YVPTIED YRQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+LVY+I + ++L EL  IYE+IK +   S ++ +PIML GNK D ++ RE+S + G+ ++  W CGF+ETSAK N NIK+MFQELLQM+
Sbjct:    7 DYRVVVFGSGGVGKSSIVLRFVRGTFRENYVPTIEDTYRQVISNNKQVCTLQITDTTGSHQFPAMQRLSITKGHAFLLVYTITNKASLEELVPIYEEIKSIRGVSELSNIPIMLVGNKCDESENREISTDTGQTLSKTWKCGFMETSAKANINIKEMFQELLQME 171          
BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000017950.1 (SMESG000017950.1)

HSP 1 Score: 142.895 bits (359), Expect = 2.035e-41
Identity = 66/162 (40.74%), Postives = 108/162 (66.67%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK+ L  +F++G F + Y PTIED+YR+ +  +     L+I+DT+G+ QF AM  + +++G  F+LVYSI + ++ N++ ++ E I   K S   ++P++L GNK DL D R V   +G+  A  WNC F+ETSA+ N N++D+F EL++
Sbjct:    3 EYKLVMLGSGGVGKSCLTVQFVQGVFLEKYDPTIEDSYRKQVEIDDNQCMLEILDTAGAEQFTAMRDMYMKSGQGFILVYSITNQTSFNDIDDLREQITRIKDS--TDIPMILVGNKCDLEDQRNVGRIQGQHKAKLWNCSFLETSARSNNNVQDIFVELVR 162          
BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000017314.1 (SMESG000017314.1)

HSP 1 Score: 142.51 bits (358), Expect = 2.164e-41
Identity = 69/162 (42.59%), Postives = 109/162 (67.28%), Query Frame = 3
Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G   VGK++L  +F++G F + Y PTIED+YR+ +  +     L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S+ NEL ++ E I   K  + + VP++L GNK DL D R V  E+G+ +A ++NC F+ETSAK+  N+ ++F +L++
Sbjct:    3 EYKLVVLGTGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGSQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSSFNELEDLREQILRVK--DTDNVPMVLVGNKCDLEDDRSVGKEQGQVLARKFNCSFMETSAKNKINVNEIFYDLVR 162          
BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000017950.1 (SMESG000017950.1)

HSP 1 Score: 135.191 bits (339), Expect = 1.261e-38
Identity = 63/157 (40.13%), Postives = 103/157 (65.61%), Query Frame = 3
Query:  252 LFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            + G+  VGK+ L  +F++G F + Y PTIED+YR+ +  +     L+I+DT+G+ QF AM  + +++G  F+LVYSI + ++ N++ ++ E I   K S   ++P++L GNK DL D R V   +G+  A  WNC F+ETSA+ N N++D+F EL++
Sbjct:    1 MLGSGGVGKSCLTVQFVQGVFLEKYDPTIEDSYRKQVEIDDNQCMLEILDTAGAEQFTAMRDMYMKSGQGFILVYSITNQTSFNDIDDLREQITRIKDS--TDIPMILVGNKCDLEDQRNVGRIQGQHKAKLWNCSFLETSARSNNNVQDIFVELVR 155          
BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000063142.1 (SMESG000063142.1)

HSP 1 Score: 108.227 bits (269), Expect = 4.982e-28
Identity = 63/167 (37.72%), Postives = 94/167 (56.29%), Query Frame = 3
Query:  219 FFDPQSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIE-DAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQEL 716
            F  P   +K+V  G   VGKTSLI RF+  +F   Y  TI  D   + +    +   LQ+ DT+G  +F ++    I   +  V+VY I + ++ N+  +  +D++  +    N+V IML GNK+DL D R+VS EEG+K A E N  FIETSAK   N+K +F+ +
Sbjct:    7 FSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERG---NDVIIMLVGNKTDLVDKRKVSTEEGEKKARELNVMFIETSAKAGYNVKQLFRRI 170          
The following BLAST results are available for this feature:
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DIRAS26.770e-6356.10DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC... [more]
DIRAS17.116e-5757.32DIRAS family GTPase 1 [Source:HGNC Symbol;Acc:HGNC... [more]
DIRAS17.116e-5757.32DIRAS family GTPase 1 [Source:HGNC Symbol;Acc:HGNC... [more]
RAP1B1.073e-4041.72RAP1B, member of RAS oncogene family [Source:HGNC ... [more]
RAP1B1.073e-4041.72RAP1B, member of RAS oncogene family [Source:HGNC ... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
drn-19.973e-6257.23GTP-binding protein drn-1 [Source:UniProtKB/Swiss... [more]
rap-19.061e-4037.76Ras-related protein Rap-1 [Source:UniProtKB/Swiss... [more]
rap-22.743e-3342.28RAP homolog (Vertebrate Rap GTPase family) [Sourc... [more]
rap-32.823e-3034.69RAP homolog (Vertebrate Rap GTPase family) [Sourc... [more]
ssr-22.736e-2835.98Sperm-Specific family, class R [Source:UniProtKB/... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG85002.164e-5558.18gene:FBgn0037754 transcript:FBtr0082139[more]
CG85002.164e-5558.18gene:FBgn0037754 transcript:FBtr0347364[more]
Rap15.480e-4143.21gene:FBgn0004636 transcript:FBtr0303154[more]
Rap15.480e-4143.21gene:FBgn0004636 transcript:FBtr0072867[more]
Rap15.480e-4143.21gene:FBgn0004636 transcript:FBtr0332671[more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
diras1a2.212e-6051.26DIRAS family, GTP-binding RAS-like 1a [Source:ZFIN... [more]
diras1b3.849e-5757.32DIRAS family, GTP-binding RAS-like 1b [Source:ZFIN... [more]
rap1b5.690e-4141.72RAP1B, member of RAS oncogene family [Source:NCBI ... [more]
rap1ab6.314e-4142.33RAP1A, member of RAS oncogene family b [Source:ZFI... [more]
rap1ab6.314e-4142.33RAP1A, member of RAS oncogene family b [Source:ZFI... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pnp7.664e-6455.95purine nucleoside phosphorylase [Source:Xenbase;Ac... [more]
DIRAS29.508e-5857.93DIRAS family GTP binding RAS like 2 [Source:NCBI g... [more]
diras11.722e-5556.10DIRAS family GTP binding RAS like 1 [Source:NCBI g... [more]
rap1b1.460e-4041.72RAP1B, member of RAS oncogene family [Source:NCBI ... [more]
aldh1a34.377e-4041.72aldehyde dehydrogenase 1 family member A3 [Source:... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Diras21.273e-6256.10DIRAS family, GTP-binding RAS-like 2 [Source:MGI S... [more]
Diras18.297e-5857.93DIRAS family, GTP-binding RAS-like 1 [Source:MGI S... [more]
Rap1b7.364e-4141.72RAS related protein 1b [Source:MGI Symbol;Acc:MGI:... [more]
Rap1a3.254e-4041.72RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:... [more]
Rasd24.897e-4041.04RASD family, member 2 [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q96HU8|DIRA2_HUMAN3.251e-6256.10GTP-binding protein Di-Ras2 OS=Homo sapiens OX=960... [more]
sp|Q95KD9|DIRA2_MACFA5.650e-6256.10GTP-binding protein Di-Ras2 OS=Macaca fascicularis... [more]
sp|Q5PR73|DIRA2_MOUSE8.906e-6256.10GTP-binding protein Di-Ras2 OS=Mus musculus OX=100... [more]
sp|Q5R6S2|DIRA2_PONAB1.389e-6155.49GTP-binding protein Di-Ras2 OS=Pongo abelii OX=960... [more]
sp|Q09930|DIRA_CAEEL1.269e-6057.23GTP-binding protein drn-1 (Fragment) OS=Caenorhabd... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3SBV74.191e-6852.22Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A087VXX69.548e-6753.61GTP binding protein Di Ras2 OS=Echinococcus multil... [more]
A0A0R3WE681.507e-6652.20Uncharacterized protein OS=Taenia asiatica OX=6051... [more]
W6US972.625e-6653.61GTP-binding protein Di-Ras2 OS=Echinococcus granul... [more]
G7YC897.964e-6655.56DIRAS family GTP-binding Ras-like 2 OS=Clonorchis ... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
diras1a3.453e-5850.25GTP-binding protein Di-Ras1-like [Source:NCBI gene... [more]
DIRAS28.619e-5756.71DIRAS family GTPase 2 [Source:NCBI gene;Acc:103025... [more]
ENSAMXT00000054511.12.200e-4843.56pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000048672.12.200e-4843.56pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
rap1ab6.019e-4142.33ras-related protein Rap-1A [Source:NCBI gene;Acc:1... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DIRAS23.197e-5657.93DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC... [more]
DIRAS21.440e-5453.57DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC... [more]
RIT21.272e-3134.44Ras like without CAAX 2 [Source:HGNC Symbol;Acc:HG... [more]
rheb1.322e-2936.69Ras homolog, mTORC1 binding [Source:ZFIN;Acc:ZDB-G... [more]
ENSPMAT00000001560.18.945e-2930.43pep scaffold:Pmarinus_7.0:GL476528:157506:173211:1... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
RSR11.103e-3942.94GTP-binding protein of the Ras superfamily; requir... [more]
RAS16.703e-3338.07GTPase involved in G-protein signaling in adenylat... [more]
RAS22.043e-2938.65GTP-binding protein; regulates nitrogen starvation... [more]
YPT62.305e-2136.02Rab family GTPase; required for endosome-to-Golgii... [more]
RHB12.501e-2032.57Putative Rheb-related GTPase; involved in regulati... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO303274.284e-4041.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO390478.245e-4041.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO334841.303e-3840.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365782.993e-3341.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO271382.993e-3341.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
diras1b2.697e-5857.32GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:... [more]
ENSORLT00000038069.11.693e-5756.71GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:... [more]
ENSORLT00000037992.11.693e-5756.71GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:... [more]
rap1aa4.399e-4142.33ras-related protein O-Krev [Source:NCBI gene;Acc:1... [more]
rap1ab5.318e-4142.33ras-related protein Rap-1A [Source:NCBI gene;Acc:1... [more]
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BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000080856.13.427e-6158.18SMESG000080856.1[more]
SMESG000017950.12.035e-4140.74SMESG000017950.1[more]
SMESG000017314.12.164e-4142.59SMESG000017314.1[more]
SMESG000017950.11.261e-3840.13SMESG000017950.1[more]
SMESG000063142.14.982e-2837.72SMESG000063142.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034513 ID=SMED30034513|Name=GTP-binding protein Di-Ras2|organism=Schmidtea mediterranea sexual|type=transcript|length=958bp
CTGAGCCATTATTCATGATTTAAATGCTGAAAATTTCTGGAATAACGTTT
TAATAAATCATGGCTGCATCTGGTAGGGTAGGACGAACTCTGAGTAAAAC
TACAGCTAAAAAGCAATTCTTGGAGAAAAACTCTAGAGACGTTGATTTAC
AGGGTACCAACAATCTCACTATACCAAACTCAATCACATCTTCAACTCCA
ACCAATATTCAAGATTCATTTTTTGATCCTCAAAGTGATTATAAAATTGT
CCTTTTTGGAGCTTCAAAGGTTGGAAAAACCTCTTTAATCAAGCGCTTCA
TCAAGGGAACATTTTCCGATATCTATGTGCCAACAATAGAAGATGCTTAC
CGACAAGTCATTAGTTATAACAAACAGATTTTCACATTACAGATAATCGA
CACTTCCGGCAGTCACCAGTTTCCAGCGATGCACAAGTTAAGCATCGAAA
CCGGAAACGCTTTCGTATTAGTTTATTCTATTCAAAGTCACTCGAACCTG
AATGAATTGGCCGAAATCTATGAAGATATAAAAGTGTCAAAGAAATCCAA
TATAAACGAAGTGCCTATTATGCTAGCTGGAAATAAAAGCGATTTGACTG
ATTGTAGAGAAGTTAGTTTTGAAGAAGGGAAAAAGGTTGCAGATGAATGG
AATTGTGGATTCATAGAGACATCAGCCAAGGATAATACAAATATTAAGGA
TATGTTTCAAGAGCTTCTACAAATGGACTGTAATCATCTTTTTGCCACTT
TAAATAGAAGTCAAACTGCGAACAAATCTTTTCGACTTTTGTCTCACACG
AGTGGGAAATTAAATAAAAAATGTGACATTGTATGATTTATTTAATTTTT
CTTTTTTAACTTAACAATTCGAGTGATTATTATATTGACTGTGCGATTAT
TGTGATAGATTTGTCAATATGTAATTCATTGTTTTTGATTTATTTTCAAA
GAAACTGG
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protein sequence of SMED30034513-orf-1

>SMED30034513-orf-1 ID=SMED30034513-orf-1|Name=SMED30034513-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=259bp
MAASGRVGRTLSKTTAKKQFLEKNSRDVDLQGTNNLTIPNSITSSTPTNI
QDSFFDPQSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQV
ISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNEL
AEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCG
FIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGK
LNKKCDIV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003924GTPase activity
GO:0005525GTP binding
GO:0000166nucleotide binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR001806Small_GTPase
IPR027417P-loop_NTPase
IPR020849Small_GTPase_Ras-type
Vocabulary: biological process
TermDefinition
GO:0007264small GTPase mediated signal transduction
GO:0007165signal transduction
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0005622intracellular
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 84..100
score: 31.49
coord: 201..223
score: 36.57
coord: 166..179
score: 51.24
coord: 101..123
score: 27.68
coord: 61..82
score: 43.17
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 58..226
e-value: 1.0E-63
score: 227.7
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 61..230
e-value: 8.6E-18
score: 75.1
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 63..222
e-value: 1.9E-10
score: 14.5
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 58..227
e-value: 9.2E-59
score: 199.7
NoneNo IPR availablePANTHERPTHR24070:SF69coord: 57..256
IPR001806Small GTPasePFAMPF00071Rascoord: 62..221
e-value: 9.5E-45
score: 152.1
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 59..219
e-value: 1.6E-24
score: 84.5
IPR020849Small GTPase superfamily, Ras-typePANTHERPTHR24070FAMILY NOT NAMEDcoord: 57..256
IPR020849Small GTPase superfamily, Ras-typePROSITEPS51421RAScoord: 56..258
score: 26.882
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 58..236