GTP-binding protein Di-Ras2

Overview


Name	GTP-binding protein Di-Ras2
Smed ID	SMED30034513
Length (bp)	958

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of GTP-binding protein Di-Ras2 (SMED30034513) t-SNE clustered cells

Violin plots show distribution of expression levels for GTP-binding protein Di-Ras2 (SMED30034513) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of GTP-binding protein Di-Ras2 (SMED30034513) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for GTP-binding protein Di-Ras2 (SMED30034513) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034513

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
nervous system	SMED30034513	dd_Smed_v4_14502_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30034513	dd_Smed_v4_14502_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30034513	dd_Smed_v4_14502_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30034513	dd_Smed_v6_14502_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Match: DIRAS2 (DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323])

HSP 1 Score: 199.519 bits (506), Expect = 6.770e-63
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Match: DIRAS1 (DIRAS family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:19127])

HSP 1 Score: 184.111 bits (466), Expect = 7.116e-57
Identity = 94/164 (57.32%), Postives = 123/164 (75.00%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PTIED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LV+S+ S  +L EL  IY+ I V  K ++ ++P+ML GNK D T  REV   E + VA EW C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLI-VQIKGSVEDIPVMLVGNKCDETQ-REVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLE 168

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Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PTIED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LV+S+ S  +L EL  IY+ I V  K ++ ++P+ML GNK D T  REV   E + VA EW C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLI-VQIKGSVEDIPVMLVGNKCDETQ-REVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLE 168

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Match: RAP1B (RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857])

HSP 1 Score: 141.739 bits (356), Expect = 1.073e-40
Identity = 68/163 (41.72%), Postives = 109/163 (66.87%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163

[Close]

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: drn-1 (GTP-binding protein drn-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09930])

HSP 1 Score: 196.052 bits (497), Expect = 9.973e-62
Identity = 95/166 (57.23%), Postives = 121/166 (72.89%), Query Frame = 3

Query:  234 SDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYN-KQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            SDY++ +FGA  VGK+S+ +RF+KGTF++ YVPTIED YRQVIS N K + TLQI DT+GSHQFPAM +LSI  GNAF+L+YS+ +  +  EL  I E +K  K + I E PIML GNK D    REVS   G+KVA    CGFIETSAK+N NI ++FQ+LL ++
Sbjct:   29 SDYRVAVFGAGGVGKSSITQRFVKGTFNENYVPTIEDTYRQVISCNQKNVCTLQITDTTGSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVPIIEMMKEVKGNAIAETPIMLVGNKKDEESKREVSSNSGQKVATNMECGFIETSAKNNENITELFQQLLALE 194

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: rap-1 (Ras-related protein Rap-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18246])

HSP 1 Score: 138.272 bits (347), Expect = 9.061e-40
Identity = 74/196 (37.76%), Postives = 118/196 (60.20%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKC 824
            +YKIV+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ + I   K  + +EVP++L GNK DL D R V  ++G+ +A ++   F+ETSAK   N+ ++F +L++   N  +    R Q             G+ NK+C
Sbjct:    3 EYKIVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLMDLRDQILRVK--DTDEVPMILVGNKCDLEDERVVGKDQGQNLARQFGSAFLETSAKAKINVSEVFYDLVR-QINRRYPESGRRQ-------------GQSNKQC 182

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: rap-2 (RAP homolog (Vertebrate Rap GTPase family) [Source:UniProtKB/TrEMBL;Acc:O17599])

HSP 1 Score: 121.324 bits (303), Expect = 2.743e-33
Identity = 63/149 (42.28%), Postives = 92/149 (61.74%), Query Frame = 3

Query:  276 KTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            K++L  +F+  TF + Y PTIED YR+ I  + Q   L+I+DT+G+ QF +M  L I+ G  FV+VYSI S    +++  + E I   K S    VPI+L GNK DL+  R+V  EEG  +A+ W+C F E SAK+N N+   F E+++
Sbjct:   16 KSALTVQFVSSTFIEKYDPTIEDFYRKEIEVDGQPSVLEILDTAGTEQFSSMRDLYIKNGQGFVVVYSITSQQTFHDIRNMKEQIVRVKGS--ENVPILLVGNKCDLSHQRQVRSEEGLALAESWSCPFTECSAKNNQNVNVTFAEIVR 162

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: rap-3 (RAP homolog (Vertebrate Rap GTPase family) [Source:UniProtKB/TrEMBL;Acc:O01312])

HSP 1 Score: 114.005 bits (284), Expect = 2.823e-30
Identity = 68/196 (34.69%), Postives = 106/196 (54.08%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKC 824
            +YKIV+ G   VGK++L  ++++G F   Y  TIED+YR++   + +   L+I+DT+G+ QF  M +    T   FVLV+S+   S    L + + DI   +     EVP++L GNKSDL + R+V   E    A++    + ETSA+ N N+ ++F+E     C  L   + +S   N   R  S  S   +KKC
Sbjct:    3 EYKIVVLGNGGVGKSALTLQYVQGIFVHTYDATIEDSYRKLSKVDAENARLEILDTAGTEQFTGMRETYYRTAQGFVLVFSLAETSTFENLKQTFTDIIAIRG---KEVPMILVGNKSDLAETRQVDESEAHNFAEKLKIPYFETSARLNQNVSEVFEE-----CAVL---IQKSAKPNIERRKWSSESEIGDKKC 187

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Match: ssr-2 (Sperm-Specific family, class R [Source:UniProtKB/TrEMBL;Acc:O02139])

HSP 1 Score: 111.694 bits (278), Expect = 2.736e-28
Identity = 59/164 (35.98%), Postives = 106/164 (64.63%), Query Frame = 3

Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW--NCGFIETSAKDNTNIKDMFQELLQM 725
            Y++V+ G++KVGKT++I+R++   FS  Y  TIED + +          L I+DT  +  FP M +LSI + +AF+LV+S+   ++  E+++I+++I  S++S++NE+PI++ GNK D+ + +++  E  K   +    +  +IE SAKDN  I D+F+ LL++
Sbjct:    6 YRLVVLGSAKVGKTNIIRRYLYNEFSSKYKETIEDLHSREFRIQGVPLPLDILDT--NFNFPDMRRLSIASASAFLLVFSVDDVTSFKEMSDIWQEI-CSRRSDLNELPIVVVGNKCDVEN-KKIYEETAKAFTNRLSSDVRYIEVSAKDNIRITDVFRTLLEL 165

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: CG8500 (gene:FBgn0037754 transcript:FBtr0082139)

HSP 1 Score: 180.644 bits (457), Expect = 2.164e-55
Identity = 96/165 (58.18%), Postives = 122/165 (73.94%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLT-DCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RFIKGTF + Y+PTIED YRQVIS NK I TLQI DT+GSHQFPAM +LSI  G+AF+LVYS+ S  +L EL  I+  IK  K ++I  +P+ML GNK D T + REVS  EG+  A  W+  F+ETSAK N N+ ++FQELL M+
Sbjct:   18 DYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELREVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNME 182

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: CG8500 (gene:FBgn0037754 transcript:FBtr0347364)

HSP 1 Score: 180.644 bits (457), Expect = 2.164e-55
Identity = 96/165 (58.18%), Postives = 122/165 (73.94%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLT-DCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RFIKGTF + Y+PTIED YRQVIS NK I TLQI DT+GSHQFPAM +LSI  G+AF+LVYS+ S  +L EL  I+  IK  K ++I  +P+ML GNK D T + REVS  EG+  A  W+  F+ETSAK N N+ ++FQELL M+
Sbjct:   18 DYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELREVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNME 182

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0303154)

HSP 1 Score: 141.739 bits (356), Expect = 5.480e-41
Identity = 70/162 (43.21%), Postives = 108/162 (66.67%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YKIV+ G+  VGK++L  +F++  F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ E I   K +  ++VP++L GNK DL + R V  E GK +A ++NC F+ETSAK   N+ D+F +L++
Sbjct:    3 EYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDT--DDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAKAKVNVNDIFYDLVR 162

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0072867)

HSP 1 Score: 141.739 bits (356), Expect = 5.480e-41
Identity = 70/162 (43.21%), Postives = 108/162 (66.67%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YKIV+ G+  VGK++L  +F++  F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ E I   K +  ++VP++L GNK DL + R V  E GK +A ++NC F+ETSAK   N+ D+F +L++
Sbjct:    3 EYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDT--DDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAKAKVNVNDIFYDLVR 162

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0332671)

HSP 1 Score: 141.739 bits (356), Expect = 5.480e-41
Identity = 70/162 (43.21%), Postives = 108/162 (66.67%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YKIV+ G+  VGK++L  +F++  F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ E I   K +  ++VP++L GNK DL + R V  E GK +A ++NC F+ETSAK   N+ D+F +L++
Sbjct:    3 EYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDT--DDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAKAKVNVNDIFYDLVR 162

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Match: diras1a (DIRAS family, GTP-binding RAS-like 1a [Source:ZFIN;Acc:ZDB-GENE-030131-5788])

HSP 1 Score: 192.2 bits (487), Expect = 2.212e-60
Identity = 102/199 (51.26%), Postives = 137/199 (68.84%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKCDIV 833
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED YRQVIS +K + TL+I DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +PIML GNKSD T  REV  +EG+  A+ W C F+ETSAK NTN+K++FQELL +D     +   RS    +        + KL  KC ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLEITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYQQV-LAIKGNVENIPIMLVGNKSDETQ-REVETKEGEAQANTWKCAFMETSAKTNTNVKELFQELLNLDKKRDMSLNMRSSKQRR--------ADKLKAKCSVM 195

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Match: diras1b (DIRAS family, GTP-binding RAS-like 1b [Source:ZFIN;Acc:ZDB-GENE-070912-620])

HSP 1 Score: 184.111 bits (466), Expect = 3.849e-57
Identity = 94/164 (57.32%), Postives = 123/164 (75.00%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ I ++ K N+  +PIML GNKSD T  REV  E+G+  +  W C F+ETSAK N N+ ++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSKQSLEELKPIYQQI-LAIKGNVENIPIMLVGNKSDETQ-REVKTEDGEAQSKTWKCAFMETSAKTNHNVTELFQELLNLE 168

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Match: rap1b (RAP1B, member of RAS oncogene family [Source:NCBI gene;Acc:321107])

HSP 1 Score: 142.124 bits (357), Expect = 5.690e-41
Identity = 68/163 (41.72%), Postives = 109/163 (66.87%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWN-CGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +WN C F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKAMEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNSCAFLESSAKSKINVNEIFYDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Match: rap1ab (RAP1A, member of RAS oncogene family b [Source:ZFIN;Acc:ZDB-GENE-040426-2738])

HSP 1 Score: 141.739 bits (356), Expect = 6.314e-41
Identity = 69/163 (42.33%), Postives = 108/163 (66.26%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ D+F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVR 163

[Close]

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ D+F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: pnp (purine nucleoside phosphorylase [Source:Xenbase;Acc:XB-GENE-1011598])

HSP 1 Score: 201.83 bits (512), Expect = 7.664e-64
Identity = 94/168 (55.95%), Postives = 127/168 (75.60%), Query Frame = 3

Query:  225 DPQSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            +P +DY++V+FGA+ VGK+SL+ RF++GTF + Y+PTIED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYS+ S  ++ EL  IYE I    K +   +PIML GNKSD T  REV   EG+ +A++W C F+ETSAK N N++++FQELL ++
Sbjct:    3 EPSNDYRVVVFGAAGVGKSSLVLRFVRGTFRETYIPTIEDTYRQVISCDKNICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSVTSKQSMEELQPIYEQI-CQIKGDTQNIPIMLVGNKSDET-LREVQASEGECLANKWKCSFMETSAKLNYNVQELFQELLNLE 168

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: DIRAS2 (DIRAS family GTP binding RAS like 2 [Source:NCBI gene;Acc:100038204])

HSP 1 Score: 186.037 bits (471), Expect = 9.508e-58
Identity = 95/164 (57.93%), Postives = 123/164 (75.00%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF + Y+PTIED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNKSD +  RE+   EG+ +A +W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRESYIPTIEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CQIKGDVESIPIMLVGNKSDESQNRELDSSEGEAMAKKWKCAFMETSAKMNHNVKELFQELLNLE 169

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: diras1 (DIRAS family GTP binding RAS like 1 [Source:NCBI gene;Acc:780240])

HSP 1 Score: 180.259 bits (456), Expect = 1.722e-55
Identity = 92/164 (56.10%), Postives = 123/164 (75.00%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PTIED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LV+S+ S  ++ EL  IY+ I +  K +I  +P+ML GNK D T  REV  +E + +A EW C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVPRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSIEELKPIYQQI-LQIKGSIENIPVMLVGNKCDETQ-REVDTKEVEALAKEWKCAFMETSAKMNYNVKELFQELLNLE 168

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: rap1b (RAP1B, member of RAS oncogene family [Source:NCBI gene;Acc:493557])

HSP 1 Score: 141.354 bits (355), Expect = 1.460e-40
Identity = 68/163 (41.72%), Postives = 109/163 (66.87%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Match: aldh1a3 (aldehyde dehydrogenase 1 family member A3 [Source:Xenbase;Acc:XB-GENE-992885])

HSP 1 Score: 140.198 bits (352), Expect = 4.377e-40
Identity = 68/163 (41.72%), Postives = 107/163 (65.64%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +    Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVEGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Diras2 (DIRAS family, GTP-binding RAS-like 2 [Source:MGI Symbol;Acc:MGI:1915453])

HSP 1 Score: 198.364 bits (503), Expect = 1.273e-62
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Diras1 (DIRAS family, GTP-binding RAS-like 1 [Source:MGI Symbol;Acc:MGI:2183442])

HSP 1 Score: 186.037 bits (471), Expect = 8.297e-58
Identity = 95/164 (57.93%), Postives = 125/164 (76.22%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PTIED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LV+S+ S  +L+EL+ IY+ I V  K ++ ++PIML GNK D T  REV   E + VA EW C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLDELSPIYKLI-VQIKGSVEDIPIMLVGNKCDETQ-REVHTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLE 168

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Rap1b (RAS related protein 1b [Source:MGI Symbol;Acc:MGI:894315])

HSP 1 Score: 141.739 bits (356), Expect = 7.364e-41
Identity = 68/163 (41.72%), Postives = 109/163 (66.87%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Rap1a (RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852])

HSP 1 Score: 140.198 bits (352), Expect = 3.254e-40
Identity = 68/163 (41.72%), Postives = 108/163 (66.26%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Match: Rasd2 (RASD family, member 2 [Source:MGI Symbol;Acc:MGI:1922391])

HSP 1 Score: 142.124 bits (357), Expect = 4.897e-40
Identity = 71/173 (41.04%), Postives = 113/173 (65.32%), Query Frame = 3

Query:  231 QSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNIN------EVPIMLAGNKSDLTD-CREVSFEEGK-KVADEWNCGFIETSAKDNTNIKDMFQELLQM 725
            ++ Y++V+ GAS+VGK+S++ RF+ G F D Y PTIED +R+V + +  ++ L I+DTSG+H FPAM +LSI TG+ F+LV+S+ S  + +E+  + + I   K    N      E+P+++ GNK+D ++ CR+V   E +  V+ + NC + E SAK NTN+ +MF  L  M
Sbjct:   17 KNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIHGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHSELCRQVPAMEAELLVSGDENCAYFEVSAKKNTNVNEMFYVLFSM 189

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q96HU8|DIRA2_HUMAN (GTP-binding protein Di-Ras2 OS=Homo sapiens OX=9606 GN=DIRAS2 PE=1 SV=1)

HSP 1 Score: 199.519 bits (506), Expect = 3.251e-62
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q95KD9|DIRA2_MACFA (GTP-binding protein Di-Ras2 OS=Macaca fascicularis OX=9541 GN=DIRAS2 PE=2 SV=1)

HSP 1 Score: 198.749 bits (504), Expect = 5.650e-62
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDMESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q5PR73|DIRA2_MOUSE (GTP-binding protein Di-Ras2 OS=Mus musculus OX=10090 GN=Diras2 PE=1 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 8.906e-62
Identity = 92/164 (56.10%), Postives = 119/164 (72.56%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q5R6S2|DIRA2_PONAB (GTP-binding protein Di-Ras2 OS=Pongo abelii OX=9601 GN=DIRAS2 PE=2 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 1.389e-61
Identity = 91/164 (55.49%), Postives = 119/164 (72.56%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++ +FGA  VGK+SL+ RF+KGTF + Y+PT+ED YR+VIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IYE I    K ++  +PIML GNK D +  REV   E + +A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRRVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQI-CEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLE 169

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Match: sp|Q09930|DIRA_CAEEL (GTP-binding protein drn-1 (Fragment) OS=Caenorhabditis elegans OX=6239 GN=drn-1 PE=1 SV=3)

HSP 1 Score: 196.052 bits (497), Expect = 1.269e-60
Identity = 95/166 (57.23%), Postives = 121/166 (72.89%), Query Frame = 3

Query:  234 SDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYN-KQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            SDY++ +FGA  VGK+S+ +RF+KGTF++ YVPTIED YRQVIS N K + TLQI DT+GSHQFPAM +LSI  GNAF+L+YS+ +  +  EL  I E +K  K + I E PIML GNK D    REVS   G+KVA    CGFIETSAK+N NI ++FQ+LL ++
Sbjct:   29 SDYRVAVFGAGGVGKSSITQRFVKGTFNENYVPTIEDTYRQVISCNQKNVCTLQITDTTGSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVPIIEMMKEVKGNAIAETPIMLVGNKKDEESKREVSSNSGQKVATNMECGFIETSAKNNENITELFQQLLALE 194

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: A0A0R3SBV7 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS2003 PE=4 SV=1)

HSP 1 Score: 221.476 bits (563), Expect = 4.191e-68
Identity = 106/203 (52.22%), Postives = 150/203 (73.89%), Query Frame = 3

Query:  234 SDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYED-IKVSKKSNINEVPIMLAGNKSDLTD-CREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH---LFATLNRSQTANKSFRLLSHTSGKLNKKCD 827
            SDY++ +FGAS VGK+SL+ RF+KGTF + YVPTIED +RQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+L+YSI + ++L+EL  IYE+ +++  ++ +  +PIML GNKSD  +  REV   +G+++A +WNCGF+ETSAK+N N+K++FQELL+M+      L    + S++  K FR L H S + + K D
Sbjct:    6 SDYRVAVFGASGVGKSSLVLRFVKGTFREAYVPTIEDTFRQVISCNKQVCTLQITDTTGSHQFPAMQRLSISRGHAFMLIYSITNRASLDELTPIYEELVRIKGQAAMQSIPIMLVGNKSDEDESSREVPTNQGEELAQKWNCGFMETSAKNNLNVKEVFQELLRMETRQNMTLVGDNSDSKSFLKCFRFLRHGSARRSPKND 208

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: A0A087VXX6 (GTP binding protein Di Ras2 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000080400 PE=4 SV=1)

HSP 1 Score: 218.009 bits (554), Expect = 9.548e-67
Identity = 104/194 (53.61%), Postives = 141/194 (72.68%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYED-IKVSKKSNINEVPIMLAGNKSDLTDC-REVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH---LFATLNRSQTANKSFRLLSHTS 803
            DY++ +FGAS VGK+SL+ RF+KGTF + Y+PTIED +RQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+L+YS+ S  +L+EL  IYE+ +++   + +  +PIML GNKSD  D  REVS  +G+ VA +WNCGF+ETSAK+N N+K++FQELL+M+      L    + S+     FR L H S
Sbjct:    7 DYRVAVFGASGVGKSSLVLRFVKGTFREAYIPTIEDTFRQVISCNKQVCTLQITDTTGSHQFPAMQRLSISRGHAFMLIYSVTSRVSLDELTPIYEELVRIKGPTAMQSIPIMLVGNKSDEGDTGREVSTIQGEAVAQKWNCGFMETSAKNNVNVKEVFQELLRMETRQNMTLVGDTSDSKGILSCFRFLRHES 200

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BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: A0A0R3WE68 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS9099 PE=4 SV=1)

HSP 1 Score: 217.624 bits (553), Expect = 1.507e-66
Identity = 107/205 (52.20%), Postives = 146/205 (71.22%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYED-IKVSKKSNINEVPIMLAGNKSDLTDC-REVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH---LFATLNRSQTANKSFRLLSHTS---GKLNKKCD 827
            DY++ +FGAS VGK+SL+ RF+KGTF + Y+PTIED +RQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+L+YSI S  +L+EL  IYE+ +++   + +  +PIML GNKSD +D  REVS  +G+ +A +WNCGF+ETSAK+N N+K++FQELL+M+      L    + S+     FR L H S   G   +K D
Sbjct:    7 DYRVAVFGASGVGKSSLVLRFVKGTFREAYIPTIEDTFRQVISCNKQVCTLQITDTTGSHQFPAMQRLSISRGHAFMLIYSITSRVSLDELTPIYEELVRIKGPAAMPSIPIMLVGNKSDESDTGREVSTVQGEAMAQKWNCGFMETSAKNNVNVKEVFQELLRMETRQNMTLVGDNSDSKGILSCFRFLRHGSTQRGSRGEKSD 211

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BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: W6US97 (GTP-binding protein Di-Ras2 OS=Echinococcus granulosus OX=6210 GN=EGR_00687 PE=4 SV=1)

HSP 1 Score: 218.009 bits (554), Expect = 2.625e-66
Identity = 104/194 (53.61%), Postives = 140/194 (72.16%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYED-IKVSKKSNINEVPIMLAGNKSDLTDC-REVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH---LFATLNRSQTANKSFRLLSHTS 803
            DY++ +FGAS VGK+SL+ RF+KGTF + Y+PTIED +RQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+L+YS+ S  +L+EL  IYE+ +++     +  +PIML GNKSD  D  REVS  +G+ VA +WNCGF+ETSAK+N N+K++FQELL+M+      L    + S+     FR L H S
Sbjct:   33 DYRVAVFGASGVGKSSLVLRFVKGTFREAYIPTIEDTFRQVISCNKQVCTLQITDTTGSHQFPAMQRLSISRGHAFMLIYSVTSRVSLDELTPIYEELVRIKGPRAMRSIPIMLVGNKSDEGDTGREVSTIQGEAVAQKWNCGFMETSAKNNVNVKEVFQELLRMETRQNMTLVGDTSDSKGILSCFRFLRHGS 226

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BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Match: G7YC89 (DIRAS family GTP-binding Ras-like 2 OS=Clonorchis sinensis OX=79923 GN=DIRAS2 PE=4 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 7.964e-66
Identity = 95/171 (55.56%), Postives = 128/171 (74.85%), Query Frame = 3

Query:  234 SDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFA 746
            +DY++ +FGA  VGKTSL+ RF++GTF + YVPTIED YRQVIS NKQ+ TLQI DT+GSHQFPAM +LS+  G+AF+LVYS+ + S+  EL  +Y ++ + K+  +  VPIML GNK D  + REVS   GK ++ +W CGF+ETSAK NTN+K++FQELL+M+     A
Sbjct:    6 TDYRVAVFGAGGVGKTSLVLRFVRGTFRETYVPTIEDTYRQVISCNKQVCTLQITDTTGSHQFPAMQRLSMSKGHAFILVYSVTNQSSFEELPHLYNELTIIKREELARVPIMLVGNKIDEGESREVSTALGKALSQKWKCGFMETSAKTNTNVKEVFQELLRMETRQNMA 176

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: diras1a (GTP-binding protein Di-Ras1-like [Source:NCBI gene;Acc:103039567])

HSP 1 Score: 186.422 bits (472), Expect = 3.453e-58
Identity = 100/199 (50.25%), Postives = 135/199 (67.84%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKCDIV 833
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED YRQVIS +K + TL+I DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +PIML GNKSD T  REV  +EG+  A+ W C F+ETSAK N N+ ++FQELL +D     +   RS    +        + KL  KC ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLEITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYQQV-LAIKGNVEGIPIMLVGNKSDETQ-REVETKEGEAQANNWKCAFMETSAKTNHNVTELFQELLNLDKKRDMSLNMRSSKQRR--------ADKLKAKCSVM 195

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: DIRAS2 (DIRAS family GTPase 2 [Source:NCBI gene;Acc:103025938])

HSP 1 Score: 182.956 bits (463), Expect = 8.619e-57
Identity = 93/164 (56.71%), Postives = 122/164 (74.39%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF + Y+PTIED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  I+E I    K ++  +PIML GNK+D T  REV   +G+ ++  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRESYIPTIEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSKQSLEELKPIFEQI-CQIKGDVESIPIMLVGNKNDETSGREVESSDGEALSKRWKCAFMETSAKTNHNVKELFQELLNLE 169

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: ENSAMXT00000054511.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000334.1:549901:552517:1 gene:ENSAMXG00000043039.1 transcript:ENSAMXT00000054511.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 162.155 bits (409), Expect = 2.200e-48
Identity = 88/202 (43.56%), Postives = 128/202 (63.37%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDM------FQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKC 824
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED Y+QVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +P+ML GNK+D T  REV  E+G+  A  W C F+ETS ++             + E    +  H + TL +++   ++   + H     + +C
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYQQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYQQM-LAIKGNVEGIPVMLVGNKNDETQ-REVQTEDGEAQAQAWKCAFMETSGQNQPQCHRALPGAAEYGEEALHEPEHRWKTLRKTKAHRQTEGEVQHYVEAEHAQC 206

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: ENSAMXT00000048672.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000334.1:542785:552517:1 gene:ENSAMXG00000043039.1 transcript:ENSAMXT00000048672.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 162.155 bits (409), Expect = 2.200e-48
Identity = 88/202 (43.56%), Postives = 128/202 (63.37%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDM------FQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGKLNKKC 824
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED Y+QVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +P+ML GNK+D T  REV  E+G+  A  W C F+ETS ++             + E    +  H + TL +++   ++   + H     + +C
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYQQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYQQM-LAIKGNVEGIPVMLVGNKNDETQ-REVQTEDGEAQAQAWKCAFMETSGQNQPQCHRALPGAAEYGEEALHEPEHRWKTLRKTKAHRQTEGEVQHYVEAEHAQC 206

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Match: rap1ab (ras-related protein Rap-1A [Source:NCBI gene;Acc:103022868])

HSP 1 Score: 141.739 bits (356), Expect = 6.019e-41
Identity = 69/163 (42.33%), Postives = 108/163 (66.26%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWN-CGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +WN C F+E+SAK   N+ D+F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNHCAFLESSAKSKINVLDIFYDLVR 163

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BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: DIRAS2 (DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323])

HSP 1 Score: 179.874 bits (455), Expect = 3.197e-56
Identity = 95/164 (57.93%), Postives = 120/164 (73.17%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF++GTF + Y+PT+ED YRQVIS +K I TLQI DT+GSHQFPAM +LSI  G+AFVLVYSI S  +L EL  IYE I  S K +   VPIML GNK D T  REV   EG+  A  W C F+ETSAK + N++++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVRGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISRGHAFVLVYSIASRQSLEELRPIYEVI-CSLKGDTEAVPIMLVGNKCDETT-REVQTAEGEAQAKAWRCAFMETSAKMDYNVRELFQELLNLE 168

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: DIRAS2 (DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323])

HSP 1 Score: 175.637 bits (444), Expect = 1.440e-54
Identity = 90/168 (53.57%), Postives = 120/168 (71.43%), Query Frame = 3

Query:  225 DPQSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            +P SDY +V+FGA  VGK+SL+ RF++GTF + YVPT+ED YRQVIS +K + TLQI DT+GSHQFPAM +L+I  G+AF+LVYS+ S  +L EL  IY D+    K +++ VP+ML  NK D T  REV+  EG+  A  W C F ETSAK + N+ + FQELL ++
Sbjct:    3 EPSSDYHVVVFGAGGVGKSSLVLRFVRGTFREAYVPTVEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLAISRGHAFLLVYSVTSRQSLEELRPIY-DVIAQIKGDVSAVPMMLVANKCDET-AREVAAGEGETQAKAWRCAFTETSAKMDYNVSEAFQELLTLE 168

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: RIT2 (Ras like without CAAX 2 [Source:HGNC Symbol;Acc:HGNC:10017])

HSP 1 Score: 116.701 bits (291), Expect = 1.272e-31
Identity = 62/180 (34.44%), Postives = 104/180 (57.78%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMF----QELLQMDCNHLFATLNRSQ 764
            +YKIV+ G   VGK+++  +FI   F + + PTIEDAY+  +  + +   L I+DT+G  +F AM    +  G  F++ YSI    +  E A+  + I   +  +  EVP++L GNK+DL + R+VS EEG+ +A E++C F ETSA     + ++F    +E+ + + + + A   RS+
Sbjct:   20 EYKIVMLGPGGVGKSAMTMQFISHRFPEDHDPTIEDAYKTQVRIDDETAHLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFQEAAQFKQLIYQVR--HTYEVPVVLVGNKTDLGEIRQVSQEEGRSLAREFSCQFFETSAALRQYVDEVFYAVVREIRRKEHDAMVAMERRSK 197

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: rheb (Ras homolog, mTORC1 binding [Source:ZFIN;Acc:ZDB-GENE-040426-1690])

HSP 1 Score: 110.153 bits (274), Expect = 1.322e-29
Identity = 62/169 (36.69%), Postives = 101/169 (59.76%), Query Frame = 3

Query:  228 PQSDY-KIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQ---FPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            PQ  Y KI + G   VGK+SL  +F++G F D Y PTIE+ + + ++ N Q F L+++DT+G  +   FP  + + I   + +VLVYS+ S  +   +  I+E  K+        VP++L GNK DL   R +S EEGK +A  WN  F+E++AK++  + ++F+ ++Q
Sbjct:    2 PQPKYRKIAVLGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKNLTVNGQEFNLKLVDTAGQDEYSMFPQTYSMDI---HGYVLVYSVTSIKSFEVVRVIHE--KLLDMVGKVHVPLVLVGNKKDLHMERVISCEEGKTLATSWNAAFMESTAKEHQTVVEVFKWMIQ 165

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001560.1 (pep scaffold:Pmarinus_7.0:GL476528:157506:173211:1 gene:ENSPMAG00000001407.1 transcript:ENSPMAT00000001560.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 108.997 bits (271), Expect = 8.945e-29
Identity = 49/161 (30.43%), Postives = 92/161 (57.14%), Query Frame = 3

Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +K+++ G+  VGK++L  +F+   F + Y PT  D+YR+ +  + +   + I+DT+G   + A+      +G  F+  +SI  H +     ++    ++ +    + +P +L GNKSDL + R+VS EE +  AD+W  G++ETSAK   N+  +F +L++
Sbjct:   15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCAFSICEHESFAGTTDLRRSEQILRVKEDDSIPFLLVGNKSDLEERRQVSIEEARARADQWGVGYVETSAKTRANVDKVFFDLMR 175

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: RSR1 (GTP-binding protein of the Ras superfamily; required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases [Source:SGD;Acc:S000003384])

HSP 1 Score: 138.658 bits (348), Expect = 1.103e-39
Identity = 70/163 (42.94%), Postives = 109/163 (66.87%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWN-CGFIETSAKDNTNIKDMFQELLQ 722
            DYK+V+ GA  VGK+ L  +F++G + D Y PTIED+YR+ I  + ++F L+I+DT+G  QF AM +L I++G  F+LVYS+    +L EL E+ E +   K S  + VP++L GNK+DL + R +S EEG +V+ +W    F ETSA   +N+ ++F +L++
Sbjct:    3 DYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDS--DRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRSNVDEVFVDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: RAS1 (GTPase involved in G-protein signaling in adenylate cyclase activation; plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes; relative distribution to the nucleus increases upon DNA replication stress; RAS1 has a paralog, RAS2, that arose from the whole genome duplication [Source:SGD;Acc:S000005627])

HSP 1 Score: 121.709 bits (304), Expect = 6.703e-33
Identity = 67/176 (38.07%), Postives = 113/176 (64.20%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQM--DCNHLFATLNR 758
            +YKIV+ G   VGK++L  +FI+  F D Y PTIED+YR+ +  + ++  L I+DT+G  ++ AM +  + TG  F+LVYS+ S ++ +EL   Y+ I+  K S+   +P+++ GNK DL + R+VS+E+G ++A + N  F+ETSAK   N+ + F  L+++  D    + ++NR
Sbjct:   10 EYKIVVVGGGGVGKSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSILDILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDY--IPVVVVGNKLDLENERQVSYEDGLRLAKQLNAPFLETSAKQAINVDEAFYSLIRLVRDDGGKYNSMNR 183

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: RAS2 (GTP-binding protein; regulates nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes; RAS2 has a paralog, RAS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005042])

HSP 1 Score: 112.849 bits (281), Expect = 2.043e-29
Identity = 63/163 (38.65%), Postives = 104/163 (63.80%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQM 725
            +YK+V+ G   VGK++L  +  +  F D Y PTIED+YR+ +  + ++  L I+DT+G  ++ AM +  +  G  F+LVYSI S S+L+EL   Y+ I   K ++   VPI++ GNKSDL + ++VS+++G  +A + N  F+ETSAK   N+++ F  L ++
Sbjct:   10 EYKLVVVGGGGVGKSALTIQLTQSHFVDEYDPTIEDSYRKQVVIDDEVSILDILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQILRVKDTDY--VPIVVVGNKSDLENEKQVSYQDGLNMAKQMNAPFLETSAKQAINVEEAFYTLARL 170

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: YPT6 (Rab family GTPase; required for endosome-to-Golgii, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6 [Source:SGD;Acc:S000004252])

HSP 1 Score: 88.5817 bits (218), Expect = 2.305e-21
Identity = 58/161 (36.02%), Postives = 90/161 (55.90%), Query Frame = 3

Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIE-DAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCG-FIETSAKDNTNIKDMFQEL 716
            YKIV  G   VGKTSLI RF+  TF D Y  TI  D   + +  + +   LQ+ DT+G  +F ++    I      ++VY I    +   + +  ED+K +++ + N V + + GNKSDL+D R++S EEG+K A       F+ETS K   N+K +F+++
Sbjct:   11 YKIVFLGEQGVGKTSLITRFMYDTFDDHYQATIGIDFLSKTMYLDDKTIRLQLWDTAGQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYIDKWIEDVK-NERGDEN-VILCIVGNKSDLSDERQISTEEGEKKAKLLGAKIFMETSTKAGYNVKALFKKI 169

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Match: RHB1 (Putative Rheb-related GTPase; involved in regulating canavanine resistance and arginine uptake; member of the Ras superfamily of G-proteins [Source:SGD;Acc:S000000622])

HSP 1 Score: 85.5001 bits (210), Expect = 2.501e-20
Identity = 57/175 (32.57%), Postives = 98/175 (56.00%), Query Frame = 3

Query:  243 KIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDC-----REVSFEEGKKVA------DEWN-CGFIETSAKDNTNIKDMFQELL-QMD 728
            KI L GA  VGKT+L  RF++  F + Y PTIE+ + ++I Y     TL+I+DT+G  +   ++  S+      +L YSI + ++ + +  +++  K+  +   + +P++L G K+DL        R V+  EG+K+A      D+ N   FIE SA+ + N+++ F  LL QM+
Sbjct:   18 KIALIGARNVGKTTLTVRFVESRFVESYYPTIENEFTRIIPYKSHDCTLEILDTAGQDEVSLLNIKSLTGVRGIILCYSIINRASFDLIPILWD--KLVDQLGKDNLPVILVGTKADLGRSTKGVKRCVTKAEGEKLASTIGSQDKRNQAAFIECSAELDYNVEETFMLLLKQME 190

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO30327 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T133])

HSP 1 Score: 139.043 bits (349), Expect = 4.284e-40
Identity = 74/178 (41.57%), Postives = 109/178 (61.24%), Query Frame = 3

Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVS----------FEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQM--DCNH 737
            ++I +FG + VGKTS++KRF  G FS+ Y PT+ED Y +V++ N  I  L   D+SGS+QFPAM +++I+  + F+LVYS+ S  +  EL  +  ++   KKS   ++P++L GNK DL + REVS          F   K    + N   +ETSAKD+ NI D+F E++ M  DC H
Sbjct:    9 HEIAVFGGAGVGKTSIVKRFYCGKFSEEYEPTVEDCYSKVLNKNGSIMVLNTTDSSGSYQFPAMREVAIKRASGFILVYSLDSKFSFEELKRLLYEVIEKKKS--ADIPVVLVGNKKDLEEQREVSSEQVVKEVMAFAREKGCEGKLNMRQVETSAKDDCNISDVFDEVVDMLEDCTH 184

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO39047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB93])

HSP 1 Score: 137.502 bits (345), Expect = 8.245e-40
Identity = 68/163 (41.72%), Postives = 110/163 (67.48%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S  N+L ++ E I   K  + ++VP++L GNK DL D R V  ++G+ +A ++ NC F+ETSAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVK--DTDDVPMVLVGNKCDLEDERVVGKDQGQNLAKQFANCTFLETSAKAKINVNEIFYDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO33484 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS29])

HSP 1 Score: 134.806 bits (338), Expect = 1.303e-38
Identity = 72/176 (40.91%), Postives = 107/176 (60.80%), Query Frame = 3

Query:  240 YKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVS----------FEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMDCNH 737
            ++I +FG + VGKTS++KRF  G FS+ Y PT+ED Y +V++ N  I  L   D+SGS+QFPAM +++I+  + F+LVYS+ S  +  EL  +  ++   KKS   ++P++L GNK DL + REVS          F   K    + N   +ETSAKD+ NI D+F E++ M   H
Sbjct:    9 HEIAVFGGAGVGKTSIVKRFYCGKFSEEYEPTVEDCYSKVLNKNGSIMVLNTTDSSGSYQFPAMREVAIKRASGFILVYSLDSKFSFEELKRLLYEVIEKKKS--ADIPVVLVGNKKDLEEQREVSSEQVVKEVMAFAREKGCEGKLNMRQVETSAKDDCNISDVFDEVVDMLDKH 182

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO36578 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI58])

HSP 1 Score: 120.168 bits (300), Expect = 2.993e-33
Identity = 69/167 (41.32%), Postives = 97/167 (58.08%), Query Frame = 3

Query:  246 IVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSD---------LTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELL 719
            IV FGAS VGKTSLI RF+   F+D Y PTIED + + + +N + + LQIIDTSG+++FPAM K+ I  G+AFVLVYS     +  +L     +I    K   N  P ++  NK+D         LTD R +       V  EW   +I+ SAK+N+ ++D+F  L+
Sbjct:    1 IVFFGASSVGKTSLILRFLGYAFNDDYSPTIEDFFIKHVFFNNETYELQIIDTSGTYEFPAMRKVDIAKGDAFVLVYSQDHPESFTKLNRYRSEILEGGK---NRHPCIVVCNKNDLPLATHLGVLTDHRGLRISAQHLVQTEWQSLWIDCSAKENSQVEDIFLRLM 164

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Match: EDO27138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI58])

HSP 1 Score: 120.168 bits (300), Expect = 2.993e-33
Identity = 69/167 (41.32%), Postives = 97/167 (58.08%), Query Frame = 3

Query:  246 IVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSD---------LTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELL 719
            IV FGAS VGKTSLI RF+   F+D Y PTIED + + + +N + + LQIIDTSG+++FPAM K+ I  G+AFVLVYS     +  +L     +I    K   N  P ++  NK+D         LTD R +       V  EW   +I+ SAK+N+ ++D+F  L+
Sbjct:    1 IVFFGASSVGKTSLILRFLGYAFNDDYSPTIEDFFIKHVFFNNETYELQIIDTSGTYEFPAMRKVDIAKGDAFVLVYSQDHPESFTKLNRYRSEILEGGK---NRHPCIVVCNKNDLPLATHLGVLTDHRGLRISAQHLVQTEWQSLWIDCSAKENSQVEDIFLRLM 164

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: diras1b (GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:101171042])

HSP 1 Score: 186.808 bits (473), Expect = 2.697e-58
Identity = 94/164 (57.32%), Postives = 125/164 (76.22%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED YRQVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  +L EL  IY+ + ++ K N+  +PIML GNKSD T  REV  ++G+  A++W C F+ETSAK N N+ ++FQELL +D
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSKQSLEELKPIYQQV-LAIKGNVEAIPIMLVGNKSDETQ-REVETKDGEAQANQWKCAFMETSAKTNHNVTELFQELLNLD 168

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: ENSORLT00000038069.1 (GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:101164795])

HSP 1 Score: 184.882 bits (468), Expect = 1.693e-57
Identity = 93/164 (56.71%), Postives = 123/164 (75.00%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED Y QVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  ++ EL  IY+ I ++ K ++  +PIML GNKSD T  REV  +EG+  A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYTQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSIEELKPIYQQI-LAIKGSVESIPIMLVGNKSDETAQREVESKEGEAQATAWKCAFMETSAKTNFNVKELFQELLALE 169

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: ENSORLT00000037992.1 (GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:101164795])

HSP 1 Score: 184.882 bits (468), Expect = 1.693e-57
Identity = 93/164 (56.71%), Postives = 123/164 (75.00%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FGA  VGK+SL+ RF+KGTF D Y+PT+ED Y QVIS +K + TLQI DT+GSHQFPAM +LSI  G+AF+LVYSI S  ++ EL  IY+ I ++ K ++  +PIML GNKSD T  REV  +EG+  A  W C F+ETSAK N N+K++FQELL ++
Sbjct:    7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTVEDTYTQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSIEELKPIYQQI-LAIKGSVESIPIMLVGNKSDETAQREVESKEGEAQATAWKCAFMETSAKTNFNVKELFQELLALE 169

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: rap1aa (ras-related protein O-Krev [Source:NCBI gene;Acc:101171247])

HSP 1 Score: 142.124 bits (357), Expect = 4.399e-41
Identity = 69/163 (42.33%), Postives = 108/163 (66.26%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K  +  +VP++L GNK DL D R V  E+G+ +A +W NC F+ETSAK   N+ ++F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEIDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVK--DTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLETSAKSKINVNEIFYDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Match: rap1ab (ras-related protein Rap-1A [Source:NCBI gene;Acc:101167529])

HSP 1 Score: 141.739 bits (356), Expect = 5.318e-41
Identity = 69/163 (42.33%), Postives = 108/163 (66.26%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEW-NCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK++L  +F++G F + Y PTIED+YR+ +  + Q   L+I+DT+G+ QF AM  L ++ G  F LVYSI + S  N+L ++ E I   K +   +VP++L GNK DL D R V  E+G+ +A +W NC F+E+SAK   N+ D+F +L++
Sbjct:    3 EYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVLDIFYDLVR 163

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000080856.1 (SMESG000080856.1)

HSP 1 Score: 194.126 bits (492), Expect = 3.427e-61
Identity = 96/165 (58.18%), Postives = 130/165 (78.79%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIK-VSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQMD 728
            DY++V+FG+  VGK+S++ RF++GTF + YVPTIED YRQVIS NKQ+ TLQI DT+GSHQFPAM +LSI  G+AF+LVY+I + ++L EL  IYE+IK +   S ++ +PIML GNK D ++ RE+S + G+ ++  W CGF+ETSAK N NIK+MFQELLQM+
Sbjct:    7 DYRVVVFGSGGVGKSSIVLRFVRGTFRENYVPTIEDTYRQVISNNKQVCTLQITDTTGSHQFPAMQRLSITKGHAFLLVYTITNKASLEELVPIYEEIKSIRGVSELSNIPIMLVGNKCDESENREISTDTGQTLSKTWKCGFMETSAKANINIKEMFQELLQME 171

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000017950.1 (SMESG000017950.1)

HSP 1 Score: 142.895 bits (359), Expect = 2.035e-41
Identity = 66/162 (40.74%), Postives = 108/162 (66.67%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G+  VGK+ L  +F++G F + Y PTIED+YR+ +  +     L+I+DT+G+ QF AM  + +++G  F+LVYSI + ++ N++ ++ E I   K S   ++P++L GNK DL D R V   +G+  A  WNC F+ETSA+ N N++D+F EL++
Sbjct:    3 EYKLVMLGSGGVGKSCLTVQFVQGVFLEKYDPTIEDSYRKQVEIDDNQCMLEILDTAGAEQFTAMRDMYMKSGQGFILVYSITNQTSFNDIDDLREQITRIKDS--TDIPMILVGNKCDLEDQRNVGRIQGQHKAKLWNCSFLETSARSNNNVQDIFVELVR 162

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000017314.1 (SMESG000017314.1)

HSP 1 Score: 142.51 bits (358), Expect = 2.164e-41
Identity = 69/162 (42.59%), Postives = 109/162 (67.28%), Query Frame = 3

Query:  237 DYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            +YK+V+ G   VGK++L  +F++G F + Y PTIED+YR+ +  +     L+I+DT+G+ QF AM  L ++ G  FVLVYSI + S+ NEL ++ E I   K  + + VP++L GNK DL D R V  E+G+ +A ++NC F+ETSAK+  N+ ++F +L++
Sbjct:    3 EYKLVVLGTGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGSQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSSFNELEDLREQILRVK--DTDNVPMVLVGNKCDLEDDRSVGKEQGQVLARKFNCSFMETSAKNKINVNEIFYDLVR 162

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000017950.1 (SMESG000017950.1)

HSP 1 Score: 135.191 bits (339), Expect = 1.261e-38
Identity = 63/157 (40.13%), Postives = 103/157 (65.61%), Query Frame = 3

Query:  252 LFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQELLQ 722
            + G+  VGK+ L  +F++G F + Y PTIED+YR+ +  +     L+I+DT+G+ QF AM  + +++G  F+LVYSI + ++ N++ ++ E I   K S   ++P++L GNK DL D R V   +G+  A  WNC F+ETSA+ N N++D+F EL++
Sbjct:    1 MLGSGGVGKSCLTVQFVQGVFLEKYDPTIEDSYRKQVEIDDNQCMLEILDTAGAEQFTAMRDMYMKSGQGFILVYSITNQTSFNDIDDLREQITRIKDS--TDIPMILVGNKCDLEDQRNVGRIQGQHKAKLWNCSFLETSARSNNNVQDIFVELVR 155

[Close]

BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Match: SMESG000063142.1 (SMESG000063142.1)

HSP 1 Score: 108.227 bits (269), Expect = 4.982e-28
Identity = 63/167 (37.72%), Postives = 94/167 (56.29%), Query Frame = 3

Query:  219 FFDPQSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIE-DAYRQVISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNELAEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCGFIETSAKDNTNIKDMFQEL 716
            F  P   +K+V  G   VGKTSLI RF+  +F   Y  TI  D   + +    +   LQ+ DT+G  +F ++    I   +  V+VY I + ++ N+  +  +D++  +    N+V IML GNK+DL D R+VS EEG+K A E N  FIETSAK   N+K +F+ +
Sbjct:    7 FSAPLQKFKLVFLGEQSVGKTSLITRFMYDSFDSTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNDNSFNQTTKWIDDVRTERG---NDVIIMLVGNKTDLVDKRKVSTEEGEKKARELNVMFIETSAKAGYNVKQLFRRI 170

The following BLAST results are available for this feature:

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DIRAS2	6.770e-63	56.10	DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC...	[more]
DIRAS1	7.116e-57	57.32	DIRAS family GTPase 1 [Source:HGNC Symbol;Acc:HGNC...	[more]
DIRAS1	7.116e-57	57.32	DIRAS family GTPase 1 [Source:HGNC Symbol;Acc:HGNC...	[more]
RAP1B	1.073e-40	41.72	RAP1B, member of RAS oncogene family [Source:HGNC ...	[more]
RAP1B	1.073e-40	41.72	RAP1B, member of RAS oncogene family [Source:HGNC ...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
drn-1	9.973e-62	57.23	GTP-binding protein drn-1 [Source:UniProtKB/Swiss...	[more]
rap-1	9.061e-40	37.76	Ras-related protein Rap-1 [Source:UniProtKB/Swiss...	[more]
rap-2	2.743e-33	42.28	RAP homolog (Vertebrate Rap GTPase family) [Sourc...	[more]
rap-3	2.823e-30	34.69	RAP homolog (Vertebrate Rap GTPase family) [Sourc...	[more]
ssr-2	2.736e-28	35.98	Sperm-Specific family, class R [Source:UniProtKB/...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG8500	2.164e-55	58.18	gene:FBgn0037754 transcript:FBtr0082139	[more]
CG8500	2.164e-55	58.18	gene:FBgn0037754 transcript:FBtr0347364	[more]
Rap1	5.480e-41	43.21	gene:FBgn0004636 transcript:FBtr0303154	[more]
Rap1	5.480e-41	43.21	gene:FBgn0004636 transcript:FBtr0072867	[more]
Rap1	5.480e-41	43.21	gene:FBgn0004636 transcript:FBtr0332671	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
diras1a	2.212e-60	51.26	DIRAS family, GTP-binding RAS-like 1a [Source:ZFIN...	[more]
diras1b	3.849e-57	57.32	DIRAS family, GTP-binding RAS-like 1b [Source:ZFIN...	[more]
rap1b	5.690e-41	41.72	RAP1B, member of RAS oncogene family [Source:NCBI ...	[more]
rap1ab	6.314e-41	42.33	RAP1A, member of RAS oncogene family b [Source:ZFI...	[more]
rap1ab	6.314e-41	42.33	RAP1A, member of RAS oncogene family b [Source:ZFI...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pnp	7.664e-64	55.95	purine nucleoside phosphorylase [Source:Xenbase;Ac...	[more]
DIRAS2	9.508e-58	57.93	DIRAS family GTP binding RAS like 2 [Source:NCBI g...	[more]
diras1	1.722e-55	56.10	DIRAS family GTP binding RAS like 1 [Source:NCBI g...	[more]
rap1b	1.460e-40	41.72	RAP1B, member of RAS oncogene family [Source:NCBI ...	[more]
aldh1a3	4.377e-40	41.72	aldehyde dehydrogenase 1 family member A3 [Source:...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Diras2	1.273e-62	56.10	DIRAS family, GTP-binding RAS-like 2 [Source:MGI S...	[more]
Diras1	8.297e-58	57.93	DIRAS family, GTP-binding RAS-like 1 [Source:MGI S...	[more]
Rap1b	7.364e-41	41.72	RAS related protein 1b [Source:MGI Symbol;Acc:MGI:...	[more]
Rap1a	3.254e-40	41.72	RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:...	[more]
Rasd2	4.897e-40	41.04	RASD family, member 2 [Source:MGI Symbol;Acc:MGI:1...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q96HU8\|DIRA2_HUMAN	3.251e-62	56.10	GTP-binding protein Di-Ras2 OS=Homo sapiens OX=960...	[more]
sp\|Q95KD9\|DIRA2_MACFA	5.650e-62	56.10	GTP-binding protein Di-Ras2 OS=Macaca fascicularis...	[more]
sp\|Q5PR73\|DIRA2_MOUSE	8.906e-62	56.10	GTP-binding protein Di-Ras2 OS=Mus musculus OX=100...	[more]
sp\|Q5R6S2\|DIRA2_PONAB	1.389e-61	55.49	GTP-binding protein Di-Ras2 OS=Pongo abelii OX=960...	[more]
sp\|Q09930\|DIRA_CAEEL	1.269e-60	57.23	GTP-binding protein drn-1 (Fragment) OS=Caenorhabd...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0R3SBV7	4.191e-68	52.22	Uncharacterized protein OS=Hymenolepis diminuta OX...	[more]
A0A087VXX6	9.548e-67	53.61	GTP binding protein Di Ras2 OS=Echinococcus multil...	[more]
A0A0R3WE68	1.507e-66	52.20	Uncharacterized protein OS=Taenia asiatica OX=6051...	[more]
W6US97	2.625e-66	53.61	GTP-binding protein Di-Ras2 OS=Echinococcus granul...	[more]
G7YC89	7.964e-66	55.56	DIRAS family GTP-binding Ras-like 2 OS=Clonorchis ...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
diras1a	3.453e-58	50.25	GTP-binding protein Di-Ras1-like [Source:NCBI gene...	[more]
DIRAS2	8.619e-57	56.71	DIRAS family GTPase 2 [Source:NCBI gene;Acc:103025...	[more]
ENSAMXT00000054511.1	2.200e-48	43.56	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000048672.1	2.200e-48	43.56	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
rap1ab	6.019e-41	42.33	ras-related protein Rap-1A [Source:NCBI gene;Acc:1...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DIRAS2	3.197e-56	57.93	DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC...	[more]
DIRAS2	1.440e-54	53.57	DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC...	[more]
RIT2	1.272e-31	34.44	Ras like without CAAX 2 [Source:HGNC Symbol;Acc:HG...	[more]
rheb	1.322e-29	36.69	Ras homolog, mTORC1 binding [Source:ZFIN;Acc:ZDB-G...	[more]
ENSPMAT00000001560.1	8.945e-29	30.43	pep scaffold:Pmarinus_7.0:GL476528:157506:173211:1...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
RSR1	1.103e-39	42.94	GTP-binding protein of the Ras superfamily; requir...	[more]
RAS1	6.703e-33	38.07	GTPase involved in G-protein signaling in adenylat...	[more]
RAS2	2.043e-29	38.65	GTP-binding protein; regulates nitrogen starvation...	[more]
YPT6	2.305e-21	36.02	Rab family GTPase; required for endosome-to-Golgii...	[more]
RHB1	2.501e-20	32.57	Putative Rheb-related GTPase; involved in regulati...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO30327	4.284e-40	41.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39047	8.245e-40	41.72	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33484	1.303e-38	40.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36578	2.993e-33	41.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27138	2.993e-33	41.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
diras1b	2.697e-58	57.32	GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:...	[more]
ENSORLT00000038069.1	1.693e-57	56.71	GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:...	[more]
ENSORLT00000037992.1	1.693e-57	56.71	GTP-binding protein Di-Ras1 [Source:NCBI gene;Acc:...	[more]
rap1aa	4.399e-41	42.33	ras-related protein O-Krev [Source:NCBI gene;Acc:1...	[more]
rap1ab	5.318e-41	42.33	ras-related protein Rap-1A [Source:NCBI gene;Acc:1...	[more]

BLAST of GTP-binding protein Di-Ras2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000080856.1	3.427e-61	58.18	SMESG000080856.1	[more]
SMESG000017950.1	2.035e-41	40.74	SMESG000017950.1	[more]
SMESG000017314.1	2.164e-41	42.59	SMESG000017314.1	[more]
SMESG000017950.1	1.261e-38	40.13	SMESG000017950.1	[more]
SMESG000063142.1	4.982e-28	37.72	SMESG000063142.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034513 ID=SMED30034513|Name=GTP-binding protein Di-Ras2|organism=Schmidtea mediterranea sexual|type=transcript|length=958bp
CTGAGCCATTATTCATGATTTAAATGCTGAAAATTTCTGGAATAACGTTT
TAATAAATCATGGCTGCATCTGGTAGGGTAGGACGAACTCTGAGTAAAAC
TACAGCTAAAAAGCAATTCTTGGAGAAAAACTCTAGAGACGTTGATTTAC
AGGGTACCAACAATCTCACTATACCAAACTCAATCACATCTTCAACTCCA
ACCAATATTCAAGATTCATTTTTTGATCCTCAAAGTGATTATAAAATTGT
CCTTTTTGGAGCTTCAAAGGTTGGAAAAACCTCTTTAATCAAGCGCTTCA
TCAAGGGAACATTTTCCGATATCTATGTGCCAACAATAGAAGATGCTTAC
CGACAAGTCATTAGTTATAACAAACAGATTTTCACATTACAGATAATCGA
CACTTCCGGCAGTCACCAGTTTCCAGCGATGCACAAGTTAAGCATCGAAA
CCGGAAACGCTTTCGTATTAGTTTATTCTATTCAAAGTCACTCGAACCTG
AATGAATTGGCCGAAATCTATGAAGATATAAAAGTGTCAAAGAAATCCAA
TATAAACGAAGTGCCTATTATGCTAGCTGGAAATAAAAGCGATTTGACTG
ATTGTAGAGAAGTTAGTTTTGAAGAAGGGAAAAAGGTTGCAGATGAATGG
AATTGTGGATTCATAGAGACATCAGCCAAGGATAATACAAATATTAAGGA
TATGTTTCAAGAGCTTCTACAAATGGACTGTAATCATCTTTTTGCCACTT
TAAATAGAAGTCAAACTGCGAACAAATCTTTTCGACTTTTGTCTCACACG
AGTGGGAAATTAAATAAAAAATGTGACATTGTATGATTTATTTAATTTTT
CTTTTTTAACTTAACAATTCGAGTGATTATTATATTGACTGTGCGATTAT
TGTGATAGATTTGTCAATATGTAATTCATTGTTTTTGATTTATTTTCAAA
GAAACTGG

protein sequence of SMED30034513-orf-1

>SMED30034513-orf-1 ID=SMED30034513-orf-1|Name=SMED30034513-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=259bp
MAASGRVGRTLSKTTAKKQFLEKNSRDVDLQGTNNLTIPNSITSSTPTNI
QDSFFDPQSDYKIVLFGASKVGKTSLIKRFIKGTFSDIYVPTIEDAYRQV
ISYNKQIFTLQIIDTSGSHQFPAMHKLSIETGNAFVLVYSIQSHSNLNEL
AEIYEDIKVSKKSNINEVPIMLAGNKSDLTDCREVSFEEGKKVADEWNCG
FIETSAKDNTNIKDMFQELLQMDCNHLFATLNRSQTANKSFRLLSHTSGK
LNKKCDIV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0000166	nucleotide binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR005225	Small_GTP-bd_dom
IPR001806	Small_GTPase
IPR027417	P-loop_NTPase
IPR020849	Small_GTPase_Ras-type

Vocabulary: **biological process**
Term	Definition
GO:0007264	small GTPase mediated signal transduction
GO:0007165	signal transduction

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0005622	intracellular

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00449	RASTRNSFRMNG	coord: 84..100 score: 31.49 coord: 201..223 score: 36.57 coord: 166..179 score: 51.24 coord: 101..123 score: 27.68 coord: 61..82 score: 43.17
None	No IPR available	SMART	SM00173	ras_sub_4	coord: 58..226 e-value: 1.0E-63 score: 227.7
None	No IPR available	SMART	SM00175	rab_sub_5	coord: 61..230 e-value: 8.6E-18 score: 75.1
None	No IPR available	SMART	SM00174	rho_sub_3	coord: 63..222 e-value: 1.9E-10 score: 14.5
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 58..227 e-value: 9.2E-59 score: 199.7
None	No IPR available	PANTHER	PTHR24070:SF69		coord: 57..256
IPR001806	Small GTPase	PFAM	PF00071	Ras	coord: 62..221 e-value: 9.5E-45 score: 152.1
IPR005225	Small GTP-binding protein domain	TIGRFAM	TIGR00231	TIGR00231	coord: 59..219 e-value: 1.6E-24 score: 84.5
IPR020849	Small GTPase superfamily, Ras-type	PANTHER	PTHR24070	FAMILY NOT NAMED	coord: 57..256
IPR020849	Small GTPase superfamily, Ras-type	PROSITE	PS51421	RAS	coord: 56..258 score: 26.882
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 58..236