Angiotensin-converting enzyme

Query:  584 DISYIYNNAKPCF--NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            D+   Y+ A  C     CL++ E  +  +  T + YE L   W  WR+  G+ I + + + ++L N  +R NG+ DA     S  +E    +    +L+  + PLY  LH YVR  L++ Y  +  +  GPIPAH+ GN+WAQ W+NI+ ++       S +    EA       P  +MF  A++F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  N+ D    HHEMGHI+Y+M Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + L+S    S   DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV RT+ DFDPG+K+HI   V YIRYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG +L   +  G S+ W E M+++TG   + + ++L +F PL  WL+  N+     +GW
Sbjct:  172 DMETTYSVATVCHPNGSCLQL-EPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM-YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLKQGWTP-RRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647          

Query:  584 DISYIYNNAKPCF--NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            D+   Y+ A  C     CL++ E  +  +  T + YE L   W  WR+  G+ I + + + ++L N  +R NG+ DA     S  +E    +    +L+  + PLY  LH YVR  L++ Y  +  +  GPIPAH+ GN+WAQ W+NI+ ++       S +  +    +  +     +MF  A++F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  N+ D    HHEMGHI+Y+M Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + L+S    S   DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV RT+ DFDPG+K+HI   V YIRYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG +L   +  G S+ W E M+++TG   + + ++L +F PL  WL+  N+     +GW
Sbjct:  172 DMETTYSVATVCHPNGSCLQL-EPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM-YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTP---RRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647          

Query:  584 DISYIYNNAKPCF--NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            D+   Y+ A  C     CL++ E  +  +  T + YE L   W  WR+  G+ I + + + ++L N  +R NG+ DA     S  +E    +    +L+  + PLY  LH YVR  L++ Y  +  +  GPIPAH+ GN+WAQ W+NI+ ++       S +    EA       P  +MF  A++F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  N+ D    HHEMGHI+Y+M Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + L+S    S   DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV RT+ DFDPG+K+HI   V YIRYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG +L   +  G S+ W E M+++TG   + + ++L +F PL  WL+  N+     +GW
Sbjct:  746 DMETTYSVATVCHPNGSCLQL-EPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM-YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLKQGWTP-RRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221          

Query:  494 PELRRKFRLI-TASIRNENESLVHELIHINNDISYIYNNAKPCF-NK---CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            P+LRR    + T    N   +   +   + +++S IY+ AK C  NK   C  + +  +  +  + + Y  L   W  W N  G  +K L+     L N   +++G  D   Y  S+ +    F+     LY  + PLY  LH +VR  L++ Y  ++ +  GPIPAH+ G++WAQ W NI+ ++     K    N    +T          MF +AEEF+ S+ +  M  EFWE SML KP D + V CH SA DF N  DFRIK CT   M   +T+HHEMGHI+YY+ Y  LP   R  AN GFHEAIGD +AL+V TPEHLHKIGL+ RV +    DI+YL+  ALEK+AFLPF   +D + WG+++G  P S  N  WW LR +YQG+ PPV R E  FD G+K+H+     YIRYFVSF++QFQF+E++C  +GY+GPLH+C+ Y+S +AG KL ++L  G S+ W+E +K + G   + ++ LLK+F P+ +WL+  N++    +GW
Sbjct:  115 PQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSL-DPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSW-YNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDK---PNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623          

Query:  584 DISYIYNNAKPCF--NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            D+   Y+ A  C     CL++ E  +  +  T + YE L   W  WR+  G+ I + + + ++L N  +R NG+ DA     S  +E    +    +L+  + PLY  LH YVR  L++ Y  +  +  GPIPAH+ GN+WAQ W+NI+ ++       S +    EA       P  +MF  A++F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  N+ D    HHEMGHI+Y+M Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + L+S    S   DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV RT+ DFDPG+K+HI   V YIRYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG +L   +  G S+ W E M+++TG   + + ++L +F PL  WL+  N+     +GW
Sbjct:  746 DMETTYSVATVCHPNGSCLQL-EPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM-YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLKQGWTP-RRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221          

Query:  494 PELRRKFRLI-TASIRNENESLVHELIHINNDISYIYNNAKPCF-NK---CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            P+LRR    + T    N   +   +   + +++S IY+ AK C  NK   C  + +  +  +  + + Y  L   W  W N  G  +K L+     L N   +++G  D   Y  S+ +    F+     LY  + PLY  LH +VR  L++ Y  ++ +  GPIPAH+ G++WAQ W NI+ ++     K    N    +T          MF +AEEF+ S+ +  M  EFWE SML KP D + V CH SA DF N  DFRIK CT   M   +T+HHEMGHI+YY+ Y  LP   R  AN GFHEAIGD +AL+V TPEHLHKIGL+ RV +    DI+YL+  ALEK+AFLPF   +D + WG+++G  P S  N  WW LR +YQG+ PPV R E  FD G+K+H+     YIRYFVSF++QFQF+E++C  +GY+GPLH+C+ Y+S +AG KL ++L  G S+ W+E +K + G   + ++ LLK+F P+ +WL+  N++    +GW
Sbjct:  115 PQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSL-DPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSW-YNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDK---PNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623          

Query:  584 DISYIYNNAKPCF--NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            D+   Y+ A  C     CL++ E  +  +  T + YE L   W  WR+  G+ I + + + ++L N  +R NG+ DA     S  +E    +    +L+  + PLY  LH YVR  L++ Y  +  +  GPIPAH+ GN+WAQ W+NI+ ++       S +  +    +  +     +MF  A++F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  N+ D    HHEMGHI+Y+M Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + L+S    S   DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV RT+ DFDPG+K+HI   V YIR                                     +KL      G S+ W E M+++TG   + + ++L +F PL  WL+  N+     +GW
Sbjct:  172 DMETTYSVATVCHPNGSCLQL-EPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM-YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTP---RRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIR-----------------------------------TAMKL------GFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 606          

Query:  662 LFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDA-ATYGLSFDFEDD------DFKSTALKLYGAILPLYKELHGYVRYCLNKFY--PGKFDKSGPIPAHIFGNV----WAQQWTNIFPIIRDCGQK---LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCH-GSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISR----VPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHIS-FGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +F+ EKD  +L   W ++      K K  +   + + N G++ NG  +  A +  +FD          D      K+Y  I P Y+ LH Y+R  L   Y  P    K GPIPAH+FG++    W+  +    P   +       LSA N Q+  T+        +MF  A  +++S G   +   +W  S+ ++   K + CH  +A D     DFR+K C +    DF   H  +    Y   Y     +FR  A+    +AI +  A     P +L+   L+      + DS    I+ L   +LE    LPF ++ D++ + L++G+VP +++N  WW++R +Y+G+  P      + D      +S       R  +S++++FQ  +++C     +G +       S++   KL E +  G S  W + +++++G  E+ ++ LL++++PL  WL+ TN+   + +GW
Sbjct:  307 IFRNEKDASRLQHLWVSYVTAIA-KSKPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSSKVHKAEFDLNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDWSAHYEQTKPFEEESETPEAMLSAFNTQNYTTK--------KMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWSKDMICHPAAALDMRAPNDFRVKACAQLGEPDFEQAHSLLVQTYYQYLYKDQSLLFREQASPVITDAIANAFAHLSTNPHYLYSQKLVPSEHLDIKDS--VIINKLYKESLESFTKLPFTIAADNWRYELFDGTVPKNKLNDRWWEIRNKYEGVRSPQPYNTSNLDALIHNSVSQVHSPATRTLISYVLKFQILKALCP----EGTILSEGCILSEDTTEKLRETMKLGSSITWLKALEMISGKGELDAQPLLEYYEPLINWLRNTNEIDQVVVGW 764          

Query:  662 LFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDA-ATYGLSFDFEDD------DFKSTALKLYGAILPLYKELHGYVRYCLNKFY--PGKFDKSGPIPAHIFGNV----WAQQWTNIFPIIRDCGQK---LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCH-GSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISR----VPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHIS-FGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +F+ EKD  +L   W ++      K K  +   + + N G++ NG  +  A +  +FD          D      K+Y  I P Y+ LH Y+R  L   Y  P    K GPIPAH+FG++    W+  +    P   +       LSA N Q+  T+        +MF  A  +++S G   +   +W  S+ ++   K + CH  +A D     DFR+K C +    DF   H  +    Y   Y     +FR  A+    +AI +  A     P +L+   L+      + DS    I+ L   +LE    LPF ++ D++ + L++G+VP +++N  WW++R +Y+G+  P      + D      +S       R  +S++++FQ  +++C     +G +       S++   KL E +  G S  W + +++++G  E+ ++ LL++++PL  WL+ TN+   + +GW
Sbjct:  307 IFRNEKDASRLQHLWVSYVTAIA-KSKPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSSKVHKAEFDLNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDWSAHYEQTKPFEEESETPEAMLSAFNTQNYTTK--------KMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWSKDMICHPAAALDMRAPNDFRVKACAQLGEPDFEQAHSLLVQTYYQYLYKDQSLLFREQASPVITDAIANAFAHLSTNPHYLYSQKLVPSEHLDIKDS--VIINKLYKESLESFTKLPFTIAADNWRYELFDGTVPKNKLNDRWWEIRNKYEGVRSPQPYNTSNLDALIHNSVSQVHSPATRTLISYVLKFQILKALCP----EGTILSEGCILSEDTTEKLRETMKLGSSITWLKALEMISGKGELDAQPLLEYYEPLINWLRNTNEIDQVVVGW 764          

Query:  527 ASIRNENESL---------VHELIHINNDISYI---YNNAKPCF----NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGP------LHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            A IR + E L           + + + N IS +   Y  A  C     + C    E  I +     +D  +LA YW  W + +G  +++ F   ++L    S+ NGH   A Y + F +ED DF+      +  +LP Y++LHGYVR+ L + Y P      G IP  + GN+W Q W  +  +     +K   +   +   +  +   V+++F + ++F++S+GM  +   FW  S+L++P D+ V CH SA DF    D RIKMCTE +   F  +HHE+GHI+YY+ Y   P ++RG+ N GFHEA+GD IAL+V + +HL  IGLI      +   I+ L   AL K+ FLPF  ++D Y + ++   +  S+ N  +W +R  + G+ PPV RTE DFDP +KYHI   V Y+RYF + + QFQF++++C  +G   P      L  C+ + SK AG  L + LSKG S++W+E ++  TG TE+   +LL++F+PLY+WLK  N +L +P+GW
Sbjct:  100 ADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYATATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLTRKASQLNGHRSYADYWVQF-YEDPDFERQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVMPAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFVDVKAEMEKQGYT---VQKLFELGDQFFQSLGMRALPPSFWNLSVLTRPDDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHELGHIQYYLQYEQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLIENGRLDEKSRINQLFKQALSKIVFLPFGYAVDKYRYAVFRNELDESQWNCGFWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLRYFAAHIFQFQFHKALCRKAGQYAPNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEFTGETEMDPAALLEYFEPLYQWLKQENSRLGVPLGW 614          

Query:  527 ASIRNENESL---------VHELIHINNDISYI---YNNAKPCF----NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGP------LHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            A IR + E L           + + + N IS +   Y  A  C     + C    E  I +     +D  +LA YW  W + +G  +++ F   ++L    S+ NGH   A Y + F +ED DF+      +  +LP Y++LHGYVR+ L + Y P      G IP  + GN+W Q W  +  +     +K   +   +   +  +   V+++F + ++F++S+GM  +   FW  S+L++P D+ V CH SA DF    D RIKMCTE +   F  +HHE+GHI+YY+ Y   P ++RG+ N GFHEA+GD IAL+V + +HL  IGLI      +   I+ L   AL K+ FLPF  ++D Y + ++   +  S+ N  +W +R  + G+ PPV RTE DFDP +KYHI   V Y+RYF + + QFQF++++C  +G   P      L  C+ + SK AG  L + LSKG S++W+E ++  TG TE+   +LL++F+PLY+WLK  N +L +P+GW
Sbjct:  100 ADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYATATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLTRKASQLNGHRSYADYWVQF-YEDPDFERQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVMPAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFVDVKAEMEKQGYT---VQKLFELGDQFFQSLGMRALPPSFWNLSVLTRPDDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHELGHIQYYLQYEQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLIENGRLDEKSRINQLFKQALSKIVFLPFGYAVDKYRYAVFRNELDESQWNCGFWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLRYFAAHIFQFQFHKALCRKAGQYAPNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEFTGETEMDPAALLEYFEPLYQWLKQENSRLGVPLGW 614          

Query:  296 AKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLIT----ASIRNENESLVHELIHINNDISYIYNNAKPC----FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQK----LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISG------YKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            AK + + +N+   +  N      + Y ++I  +N + K       +K   ++   + KF W+S++S +L+R+F+ +T    A++  ++ +   EL+   + +   +   K C      KC    +  I ++    +D+E+LA YW  + +  G  ++  F R ++L    ++ N     A   L  ++EDD F+     ++  I PLY+++HGYVR+ L K Y      ++GPIP H+ GN+WAQQW+ I  I+    +K    +SAE       E     P+ +MF + ++F+ S+ + K+  +FW++S++ KP D + + CH SA DF    D RIK CT        T+HHE+GHI+Y++ Y H P ++R  AN GFHEA+GD ++L+V TP+HL KIGL+          I+ L  TAL+K+ FLPFA +MD Y W L+ G V  +  N  +W LR  Y G+ PPV R+E DFD  +KYHIS  V Y+RY VSF+IQFQFY+S C  +G       + PL  C+ Y S  AG     MLS G S+ W + ++   G   +  +++ ++F+PL  WL+  N K N+ IGW
Sbjct:   25 AKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYA---ELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWLD-EYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAE------MEKQGYTPL-KMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGW 606          

Query:  296 AKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLIT----ASIRNENESLVHELIHINNDISYIYNNAKPC----FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQK----LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISG------YKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            AK + + +N+   +  N      + Y ++I  +N + K       +K   ++   + KF W+S++S +L+R+F+ +T    A++  ++ +   EL+   + +   +   K C      KC    +  I ++    +D+E+LA YW  + +  G  ++  F R ++L    ++ N     A   L  ++EDD F+     ++  I PLY+++HGYVR+ L K Y      ++GPIP H+ GN+WAQQW+ I  I+    +K    +SAE       E     P+ +MF + ++F+ S+ + K+  +FW++S++ KP D + + CH SA DF    D RIK CT        T+HHE+GHI+Y++ Y H P ++R  AN GFHEA+GD ++L+V TP+HL KIGL+          I+ L  TAL+K+ FLPFA +MD Y W L+ G V  +  N  +W LR  Y G+ PPV R+E DFD  +KYHIS  V Y+RY VSF+IQFQFY+S C  +G       + PL  C+ Y S  AG     MLS G S+ W + ++   G   +  +++ ++F+PL  WL+  N K N+ IGW
Sbjct:   25 AKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYA---ELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWLD-EYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAE------MEKQGYTPL-KMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGW 606          

Query:  296 AKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLIT----ASIRNENESLVHELIHINNDISYIYNNAKPC----FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQK----LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISG------YKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            AK + + +N+   +  N      + Y ++I  +N + K       +K   ++   + KF W+S++S +L+R+F+ +T    A++  ++ +   EL+   + +   +   K C      KC    +  I ++    +D+E+LA YW  + +  G  ++  F R ++L    ++ N     A   L  ++EDD F+     ++  I PLY+++HGYVR+ L K Y      ++GPIP H+ GN+WAQQW+ I  I+    +K    +SAE       E     P+ +MF + ++F+ S+ + K+  +FW++S++ KP D + + CH SA DF    D RIK CT        T+HHE+GHI+Y++ Y H P ++R  AN GFHEA+GD ++L+V TP+HL KIGL+          I+ L  TAL+K+ FLPFA +MD Y W L+ G V  +  N  +W LR  Y G+ PPV R+E DFD  +KYHIS  V Y+RY VSF+IQFQFY+S C  +G       + PL  C+ Y S  AG     MLS G S+ W + ++   G   +  +++ ++F+PL  WL+  N K N+ IGW
Sbjct:   25 AKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYA---ELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWLD-EYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAE------MEKQGYTPL-KMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGW 606          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDIN--------KKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRNENESLVHE-LIHINN---DISYIYNNAKPCFNK--CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            E YP    +   E  AK + D+ N  +    N +    + Y+TDI         +KNLE+    +  G +         +    K           R+++     E  +L  E L+  NN    +  +Y+ A  C +K  CL + +  + K+    +DY++L   W  WRN +G++I+  + R ++L N  ++ NGH D   +  S  +E   F+     L+  + PLY  +H YVR  L K Y P + +  GPIPAH+ GN+WAQ W+ I  ++         +       +  +    ++MF  ++ F+ S+G+  M  EFW +SML KP D + V CH SA DF N  DFRIK CT   M D  T+HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V D+    I++LM+ AL+K+AFLPF   MD + W +++G +  SE NK WW+LR +YQGL PPV RTE DFDPG+K+HI   V YIRYFVSF+IQFQF++ +C+ +G+KGPLH C+ YQSKEAG  L +++  G S+ W E MKI+TG  ++  + L+++F PL +WL+  N+K    +GW
Sbjct:  662 EGYPEDIGKITDEMQAKQFLDEYNSTAEEVWNAYTESSWTYNTDITEAHKDNMLQKNLEMANHTKIYGLEARKYDTSDFQDESVK-----------RILSKLSDLERAALSAEDLVEYNNLLASMETLYSVATVCKDKSNCLPL-DPDLNKIMAESRDYDELLFAWQGWRNASGREIRDSYKRYVELANSAAKSNGHTDNGAFWRSL-YETPTFEQDLEALWKDLEPLYLSVHAYVRRALYKKYGPERINLKGPIPAHLLGNMWAQTWSGIMDLVNPYPDATQVDATPAMIAQGWTP---KRMFEESDRFFTSLGLLPMPPEFWNKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPISFRDGANPGFHEAIGDVLALSVATPKHLQSIGLLDKVEDNAESTINFLMSIALDKIAFLPFGYLMDQWRWKVFDGRISSSEYNKEWWNLRMKYQGLCPPVPRTEKDFDPGAKFHIPANVPYIRYFVSFVIQFQFHKGLCDAAGHKGPLHNCDIYQSKEAGKLLSDVMKMGFSKPWPEAMKIITGQPKMSVQPLMEYFKPLIEWLEKENEKNGDVLGW 1249          

Query:  575 INNDISYIYNNAKPCFN--KCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPII--------RDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            I + +  IY+ AK C +  +C  + E  + ++  T + Y++L   W  W N +G  +K L+   +++ N  S+ +G +D   Y  S+ +E   FK     L+  + PLY+ LH +VR  L  +Y P   +  GPIPAH+ GN+W+Q W NI+ ++         D    + A+ Y               MF +AEEF+ S+G+ +M  EFW++SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH+EYY+ Y   P  FR  AN GFHEAIGD ++L+V TP+HLH I L+ ++ D    DI+YL+  ALEK+AFLPF   +D + W +++G  P    N  WW LR +YQG+ PP +RTE+ FD G KYHI     YIRYFVSF++QFQF+E +C  +G+ GPLH+C+ Y+S+EAG  L ++L  G S+ W + ++   G  ++ +  L+ +F P+  WL+  N+K    +GW
Sbjct:  173 ILSQMDSIYSTAKVCPSPEECWSL-EPELQEIMATSRSYKRLLYAWEGWHNSSGVPLKSLYAEFVKISNKASQMDGFKDTGEYWRSW-YESPTFKQDLENLFKQLEPLYQNLHAFVRRKLYDYYGPKYINLKGPIPAHLLGNMWSQTWNNIYNMMIPFPNRPNVDVTNTMIAKGYN-----------ATHMFRVAEEFFTSLGLLEMPPEFWDKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVSFRRGANPGFHEAIGDVLSLSVSTPKHLHSIDLLDQLTDDAESDINYLLKMALEKIAFLPFGYLIDQWRWSVFSGETPPDRYNADWWYLRTKYQGICPPTRRTEEHFDAGGKYHIPGNTPYIRYFVSFILQFQFHEKLCKEAGHTGPLHKCDIYKSREAGAVLEKVLKAGSSEPWTQVLQEALGTDKMDATPLMSYFLPVTTWLREQNEKTGETLGW 651          

Query:  563 ELIHINNDISYIYNNAKPCF----NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATY---------GLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQ------MFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLI-SRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            EL +I +++S IYN A  C       C +  E G+  +    +DY++    W  WR  TG K++ L+ + + L+N  ++ N +ED   Y            + +  D     A ++Y  ILPLYKELH YVR  L   YPG       +PAH+ G++W + WTN++P++           Y D    ++S   VEQ      +F  AE+F+ S+ M  M D FW  SM  KP+++ V CH +A D  N  DFRIKMCT+ NM DF T+HHEMGH +Y MAY + P + R  AN GFHEA+G+ ++L+  TP HL  +GL+ S        DI++L+  AL  V  LPF   ++ + W ++   +P  E  + WW ++    G+   V R E   DP + +H+S   S+IRYF   + QFQF E++C  +G+ GPL++C+   S +AG KL  ML  G+S +W   ++ + G T++ S+ LL +F  L +WLK  N+K N   GW
Sbjct:  114 ELRNIMSEMSTIYNTATVCKIDDPTDC-QTLEPGLESIMAESRDYDERLHVWEGWRVATGMKMRPLYEKYVDLKNEAAKLNNYEDHGDYWRGDYETIDDPKYSYSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVYPGHIGSDACLPAHLLGDMWGRFWTNLYPLMIP---------YPDRPDIDVSSAMVEQGWDEIRLFKEAEKFFMSVNMPAMFDNFWNNSMFIKPEERDVVCHPTAWDMGNRKDFRIKMCTKVNMDDFLTVHHEMGHNQYQMAYRNHPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPSDFKQDYETDINFLLKQALTIVGTLPFTYMLEEWRWQVFKAKIPKDEWMQQWWQMKRELVGVAEAVPRDETYCDPPALFHVSGDYSFIRYFTRTIYQFQFQEALCKAAGHTGPLYKCDITNSTKAGDKLRHMLELGRSMSWTRALEEVAGTTKMDSQPLLHYFSTLMEWLKEENQKNNRVPGW 607          

Query:  563 ELIHINNDISYIYNNAKPC----FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATY---------GLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQ------MFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLI-SRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            EL +I +++S IYN A  C       C +  E G+  +    +DY++    W  WR  TG K++ L+ + + L+N  ++ N +ED   Y            + +  D     A ++Y  ILPLYKELH YVR  L   YPG       +PAH+ G++W + WTN++P++           Y D    ++S   VEQ      +F  AE+F+ S+ M  M D FW  SM  KP+++ V CH +A D  N  DFRIKMCT+ NM DF T+HHEMGH +Y MAY + P + R  AN GFHEA+G+ ++L+  TP HL  +GL+ S        DI++L+  AL  V  LPF   ++ + W ++   +P  E  + WW ++    G+   V R E   DP + +H+S   S+IRYF   + QFQF E++C  +G+ GPL++C+   S +AG KL  ML  G+S +W   ++ + G T++ S+ LL +F  L +WLK  N+K N   GW
Sbjct:  114 ELRNIMSEMSTIYNTATVCKIDDPTDC-QTLEPGLESIMAESRDYDERLHVWEGWRVATGMKMRPLYEKYVDLKNEAAKLNNYEDHGDYWRGDYETIDDPKYSYSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVYPGHIGSDACLPAHLLGDMWGRFWTNLYPLMIP---------YPDRPDIDVSSAMVEQGWDEIRLFKEAEKFFMSVNMPAMFDNFWNNSMFIKPEERDVVCHPTAWDMGNRKDFRIKMCTKVNMDDFLTVHHEMGHNQYQMAYRNHPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPSDFKQDYETDINFLLKQALTIVGTLPFTYMLEEWRWQVFKAKIPKDEWMQQWWQMKRELVGVAEAVPRDETYCDPPALFHVSGDYSFIRYFTRTIYQFQFQEALCKAAGHTGPLYKCDITNSTKAGDKLRHMLELGRSMSWTRALEEVAGTTKMDSQPLLHYFSTLMEWLKEENQKNNRVPGW 607          

Query:  494 PELRRKFRLIT----ASIRNENESLVHELIHINNDISYIYNNAKPC--FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            PE +R  R ++    A++  E +    E   I +D+  IY+ AK C   N      +  + ++    +DY++L   W  WR+ +G++I++ + R +QL N  ++ NG+ D   Y  S+ +E    +S   KLY  + PLY  LH YVR  L K Y  K  +  GPIPAH+ GN+WAQ W+NI+ ++            Q +AT  +     ++MF  ++ F++S+G+  M  EFW++SM+ KP+D+ V CH SA DF N  DFRIK CT  NM D  T+HHEMGH++Y++ Y   P +FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V D+   DI+YLM+ AL+K+AFLPF   MD + W +++G  P SE N+ WW+LR +YQGL+PPV RTE+DFDPG+K+HI   V YIRYF+SF+IQFQF+E++C  +  +GPLH+C+ YQS +AG  L + +  G S+ W E M+ +TG   + + +LLK+F PL  WL   N K    +GW
Sbjct:   23 PETQRILRKLSEIDKAALSEEEQK---EYNQITSDMETIYSVAKVCKDGNTNCHPLDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAYWRSW-YETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVPYPNAA-----QVDATPAMINWTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 527          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLIT----ASIRNENESLVHELIHINNDISYIYNNAKPC--FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + YP   ++ A+EK A  +     + +    N +    + Y+T+I + N +L K      S   L+   +++ + +  F+ PE +R  R ++    A++  E +    E   I +D+  IY+ AK C   N      +  + ++    +DY++L   W  WR+ +G++I++ + R +QL N  ++ NG+ D   Y  S+ +E    +S   KLY  + PLY  LH YVR  L K Y  K  +  GPIPAH+ GN+WAQ W+NI+ ++         +       +N +    ++MF  ++ F++S+G+  M  EFW++SM+ KP+D+ V CH SA DF N  DFRIK CT  NM D  T+HHEMGH++Y++ Y   P +FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V D+   DI+YLM+ AL+K+AFLPF   MD + W +++G  P SE N+ WW+LR +YQGL+PPV RTE+DFDPG+K+HI   V YIRYF+SF+IQFQF+E++C  +  +GPLH+C+ YQS +AG  L + +  G S+ W E M+ +TG   + + +LLK+F PL  WL   N K    +GW
Sbjct:  605 DGYPGDIEKIANEKEADTFLSDYTKSAEVVWNDYTEASWAYNTNITEANKQLDKNL--AMSGHTLQYGLQARNYDYSDFQDPETQRILRKLSEIDKAALSEEEQK---EYNQITSDMETIYSVAKVCKDGNTNCHPLDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAYWRSW-YETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVPYPNAAQVDATPAMIAKNWTP---KRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1190          

Query:  512 FRLITASIR-----NENESLVHELIHINNDISYIYNNAKPC----FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQK--LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
             + I +SIR     N N +   E   I +++  IY+ AK C      KC  + E  I ++  T + Y+KL   W  W N  G  +K+ +LR +QL N   R +G++D   Y  S+ +    F+     LY  + PLY  LH +VR  L + Y  K+ +  GPIPAH+FGN+W+QQW NI+ ++     K  +   N   E   N +      MF ++EEF+ S+G+ +M  EFWE+SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH+EYY+ Y   P  +R  AN GFHEAIGD ++L+V TP HL  IGL+  V + K  DI+YL+  ALEK+AFLPF   +D + W +++G  P +  N  WW+LR +YQG+ PP+ R ++ FD G+KYHI     YIRYFVSF++QFQF++++C  + + GPLH C+ Y+S+EAG  L ++L  G S++W+E +K +TG+ ++    LL++F P+ +WL   N K N  +GW
Sbjct:   88 LKKIISSIRTLGASNLNLTAREEYNTILSEMDSIYSTAKVCPPNATAKCWSL-EPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAYWRSW-YASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMMIPFPDKTNIDVTNTMREKGWNAT-----HMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDTVTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 594          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLIT----ASIRNENESLVHELIHINNDISYIYNNAKPC--FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + YP   ++ A+EK A  +     + +    N +    + Y+T+I + N ++        S   L+   +++ + +  F+ PE +R  R ++    A++  E +    E   I +D+  IY+ AK C   N      +  + ++    +DY++L   W  WR+ +G++I++ + R +QL N  ++ NG+ D   Y  S+ +E    +S   KLY  + PLY  LH YVR  L K Y  K  +  GPIPAH+ GN+WAQ W+NI+ ++            Q +AT  +     ++MF  ++ F++S+G+  M  EFW++SM+ KP+D+ V CH SA DF N  DFRIK CT  NM D  T+HHEMGH++Y++ Y   P +FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V D+   DI+YLM+ AL+K+AFLPF   MD + W +++G  P SE N+ WW+LR +YQGL+PPV RTE+DFDPG+K+HI   V YIRYF+SF+IQFQF+E++C  +  +GPLH+C+ YQS +AG  L + +  G S+ W E M+ +TG   + + +LLK+F PL  WL   N K    +GW
Sbjct:  628 DGYPGDIEKIANEKEADTFLSDYTKSAEVVWNDYTEASWAYNTNITEANKQVMLDKNLAMSGHTLQYGLQARNYDYSDFQDPETQRILRKLSEIDKAALSEEEQK---EYNQITSDMETIYSVAKVCKDGNTNCHPLDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAYWRSW-YETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVPYPNAA-----QVDATPAMINWTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1213          

Query:  512 FRLITASIR-----NENESLVHELIHINNDISYIYNNAKPC----FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQK--LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
             + I +SIR     N N +   E   I +++  IY+ AK C      KC  + E  I ++  T + Y+KL   W  W N  G  +K+ +LR +QL N   R +G++D   Y  S+ +    F+     LY  + PLY  LH +VR  L + Y  K+ +  GPIPAH+FGN+W+QQW NI+ ++     K  +   N   E   N +      MF ++EEF+ S+G+ +M  EFWE+SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH+EYY+ Y   P  +R  AN GFHEAIGD ++L+V TP HL  IGL+  V + K  DI+YL+  ALEK+AFLPF   +D + W +++G  P +  N  WW+LR +YQG+ PP+ R ++ FD G+KYHI     YIRYFVSF++QFQF++++C  + + GPLH C+ Y+S+EAG  L ++L  G S++W+E +K +TG+ ++    LL++F P+ +WL   N K N  +GW
Sbjct:  111 LKKIISSIRTLGASNLNLTAREEYNTILSEMDSIYSTAKVCPPNATAKCWSL-EPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAYWRSW-YASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMMIPFPDKTNIDVTNTMREKGWNAT-----HMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDTVTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 617          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLIT----ASIRNENESLVHELIHINNDISYIYNNAKPC--FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + YP   ++ A+EK A  +     + +    N +    + Y+T+I + N +L K      S   L+   +++ + +  F+ PE +R  R ++    A++  E +    E   I +D+  IY+ AK C   N      +  + ++    +DY++L   W  WR+ +G++I++ + R +QL N  ++ NG+ D   Y  S+ +E    +S   KLY  + PLY  LH YVR  L K Y  K  +  GPIPAH+ GN+WAQ W+NI+ ++         +       +N +    ++MF  ++ F++S+G+  M  EFW++SM+ KP+D+ V CH SA DF N  DFRIK CT  NM D  T+HHEMGH++Y++ Y   P +FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V D+   DI+YLM+ AL+K+AFLPF   MD + W +++G  P SE N+ WW+LR +YQGL+PPV RTE+DFDPG+K+HI   V YIRYF+SF+IQFQF+E++C  +  +GPLH+C+ YQS +AG  L + +  G S+ W E M+ +TG   + + +LLK+F PL  WL   N K    +GW
Sbjct:  623 DGYPGDIEKIANEKEADTFLSDYTKSAEVVWNDYTEASWAYNTNITEANKQLDKNL--AMSGHTLQYGLQARNYDYSDFQDPETQRILRKLSEIDKAALSEEEQK---EYNQITSDMETIYSVAKVCKDGNTNCHPLDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAYWRSW-YETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVPYPNAAQVDATPAMIAKNWTP---KRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1208          

Query:  512 FRLITASIR-----NENESLVHELIHINNDISYIYNNAKPC----FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQK--LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
             + I +SIR     N N +   E   I +++  IY+ AK C      KC  + E  I ++  T + Y+KL   W  W N  G  +K+ +LR +QL N   R +G++D   Y  S+ +    F+     LY  + PLY  LH +VR  L + Y  K+ +  GPIPAH+FGN+W+QQW NI+ ++     K  +   N   E   N +      MF ++EEF+ S+G+ +M  EFWE+SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH+EYY+ Y   P  +R  AN GFHEAIGD ++L+V TP HL  IGL+  V + K  DI+YL+  ALEK+AFLPF   +D + W +++G  P +  N  WW+LR +YQG+ PP+ R ++ FD G+KYHI     YIRYFVSF++QFQF++++C  + + GPLH C+ Y+S+EAG  L ++L  G S++W+E +K +TG+ ++    LL++F P+ +WL   N K N  +GW
Sbjct:  106 LKKIISSIRTLGASNLNLTAREEYNTILSEMDSIYSTAKVCPPNATAKCWSL-EPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAYWRSW-YASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMMIPFPDKTNIDVTNTMREKGWNAT-----HMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDTVTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 612          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLIT----ASIRNENESLVHELIHINNDISYIYNNAKPC--FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + YP   ++ A+EK A  +     + +    N +    + Y+T+I + N +L K      S   L+   +++ + +  F+ PE +R  R ++    A++  E +    E   I +D+  IY+ AK C   N      +  + ++    +DY++L   W  WR+ +G++I++ + R +QL N  ++ NG+ D   Y  S+ +E    +S   KLY  + PLY  LH YVR  L K Y  K  +  GPIPAH+ GN+WAQ W+NI+ ++         +       +N +    ++MF  ++ F++S+G+  M  EFW++SM+ KP+D+ V CH SA DF N  DFRIK CT  NM D  T+HHEMGH++Y++ Y   P +FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V D+   DI+YLM+ AL+K+AFLPF   MD + W +++G  P SE N+ WW+LR +YQGL+PPV RTE+DFDPG+K+HI   V YIRYF+SF+IQFQF+E++C  +  +GPLH+C+ YQS +AG  L + +  G S+ W E M+ +TG   + + +LLK+F PL  WL   N K    +GW
Sbjct:  630 DGYPGDIEKIANEKEADTFLSDYTKSAEVVWNDYTEASWAYNTNITEANKQLDKNL--AMSGHTLQYGLQARNYDYSDFQDPETQRILRKLSEIDKAALSEEEQK---EYNQITSDMETIYSVAKVCKDGNTNCHPLDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAYWRSW-YETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVPYPNAAQVDATPAMIAKNWTP---KRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1215          

Query:  512 FRLITASIR-----NENESLVHELIHINNDISYIYNNAKPC----FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQK--LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
             + I +SIR     N N +   E   I +++  IY+ AK C      KC  + E  I ++  T + Y+KL   W  W N  G  +K+ +LR +QL N   R +G++D   Y  S+ +    F+     LY  + PLY  LH +VR  L + Y  K+ +  GPIPAH+FGN+W+QQW NI+ ++     K  +   N   E   N +      MF ++EEF+ S+G+ +M  EFWE+SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH+EYY+ Y   P  +R  AN GFHEAIGD ++L+V TP HL  IGL+  V + K  DI+YL+  ALEK+AFLPF   +D + W +++G  P +  N  WW+LR +YQG+ PP+ R ++ FD G+KYHI     YIRYFVSF++QFQF++++C  + + GPLH C+ Y+S+EAG  L ++L  G S++W+E +K +TG+ ++    LL++F P+ +WL   N K N  +GW
Sbjct:  113 LKKIISSIRTLGASNLNLTAREEYNTILSEMDSIYSTAKVCPPNATAKCWSL-EPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAYWRSW-YASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMMIPFPDKTNIDVTNTMREKGWNAT-----HMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDTVTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 619          

Query:  584 DISYIYNNAKPCFNK--CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKM--PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            D+   Y+ +  C+    C+ + E  +  +  T + YE+L   W +WR+  G+ I   F + ++  N  ++ NG+ DA     S  +E D+ +    KLY  + PLY  LH YVR  L++ Y  ++ +  GPIPAH+ GN+WAQ W+NI+ ++       SA N   +ATE + K      ++F  A+ F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  NM D    HHEMGHI+Y+M Y  LP  FR  AN GFHEAIGD +AL+V TP+HL+ + L+S       +DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV R++ DFDPGSK+H+   V Y+RYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG  L + +  G S+ W E MK++TG   + + +++ +F PL +WL   N++    +GW
Sbjct:  171 DMETTYSLSNICYTNGTCMPL-EPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGDSWRSL-YESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFP---SAPNI--DATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 646          

Query:  212 PSVFDSYYHMTDLESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRR---KFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKM--PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            P + D+Y    DLE+     D +  E      +D+  ++ +   N +A  +++Y+T+I  +  ++        S   LK   ++K F   +F++  ++R   K + +  ++    E   +  I ++ + +Y  +N       C+ + E  +  +  T + YE+L   W +WR+  G+ I   F + ++  N  ++ NG+ DA     S  +E D+ +    KLY  + PLY  LH YVR  L++ Y  ++ +  GPIPAH+ GN+WAQ W+NI+ ++       SA N   +ATE + K      ++F  A+ F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  NM D    HHEMGHI+Y+M Y  LP  FR  AN GFHEAIGD +AL+V TP+HL+ + L+S       +DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV R++ DFDPGSK+H+   V Y+RYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG  L + +  G S+ W E MK++TG   + + +++ +F PL +WL   N++    +GW
Sbjct:  402 PPLPDNYPEGIDLETDEAKADRFVEE------YDRTAQVLL---NEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPL-EPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGDSWRSL-YESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFP---SAPNI--DATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 993          

Query:  833 FEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +E   F+ +   +Y  + PLY  LH YVR  L++ Y  K+ +  GPIPAH+ G++WAQ W NI+ ++     K    N    +T          MF ++EEF+ S+G+  M  EFW  SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH++YY+ Y  L    R  AN GFHEAIGD +AL+V TP HLHKIGL+  V +    DI+YL+  ALEK+AFLPF   +D + WG+++G  P S  N  WW LR +YQG+ PPV R E  FD G+K+HI     YIRYFVSF++QFQF++++C  +G++GPLH+C+ YQS +AG KL ++L  G S+ W+E +K L G+  + +++LL++F P+ +WL+  N++    +GW
Sbjct:    3 YESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDK---PNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGW 395          

Query:  212 PSVFDSYYHMTDLESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRR---KFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKM--PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            P + D+Y    DLE+     D +  E      +D+  ++ +   N +A  +++Y+T+I  +  ++        S   LK   ++K F   +F++  ++R   K + +  ++    E   +  I ++ + +Y  +N       C+ + E  +  +  T + YE+L   W +WR+  G+ I   F + ++  N  ++ NG+ DA     S  +E D+ +    KLY  + PLY  LH YVR  L++ Y  ++ +  GPIPAH+ GN+WAQ W+NI+ ++       SA N   +ATE + K      ++F  A+ F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  NM D    HHEMGHI+Y+M Y  LP  FR  AN GFHEAIGD +AL+V TP+HL+ + L+S       +DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV R++ DFDPGSK+H+   V Y+RYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG  L + +  G S+ W E MK++TG   + + +++ +F PL +WL   N++    +GW
Sbjct:  635 PPLPDNYPEGIDLETDEAKADRFVEE------YDRTAQVLL---NEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPL-EPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGDSWRSL-YESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFP---SAPNI--DATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1226          

Query:  509 KFRLITASIRN---ENESLVHELIH--INNDISYIYNNAKPCF-NK---CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            K R I  SIR     N  L     +  + +++S IY+  K CF NK   C  + +  +  +  + + Y KL   W  W +  G  +K L+     + N   R++   D   +  S+ +E   F+ +   +Y  + PLY  LH YVR  L++ Y  K+ +  GPIPAH+ G++WAQ W NI+ ++     K    N    +T          MF ++EEF+ S+G+  M  EFW  SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH++YY+ Y  L    R  AN GFHEAIGD +AL+V TP HLHKIGL+  V +    DI+YL+  ALEK+AFLPF   +D + WG+++G  P S  N  WW LR +YQG+ PPV R E  FD G+K+HI     YIRYFVSF++QFQF++++C  +G++GPLH+C+ YQS +AG KL ++L  G S+ W+E +K L G+  + +++LL++F P+ +WL+  N++    +GW
Sbjct:  121 KLRRIIGSIRTLGPANLPLAQRQQYNSLLSNMSRIYSTGKVCFPNKTATCWSL-DPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAFWRSW-YESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDK---PNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGW 628          

Query:  272 DEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRNENESLV--HELIHINNDISYI---YNNAKPCFNK--CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKM------PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +++ SE  AKL+     + +    N F    + Y T+I K+N +   + +   S+  L    +++ F    F + +++R  R     ++N ++S +   +L+  N  ++Y+   YN A+ C ++  CL + E  + ++  T +D ++L   W  WR+  G++++ +F   ++L N  ++ NG++D      S  +E D  +    +LY  + PLY  LH YVR  L ++Y P   D  GPIPAH+ GN+WAQ W NI  ++           Y  +A E+++ +        E+MF  A  F+ S+GM      FW +SM+ KP D + V CH S+ +F    DFR+K CTE  + D  ++ H+MGHI+Y++ Y +L  I++  A+  F EA+G  IAL+V + ++L   GL+S+       ++++L+  ALEK+AF+PF+  +D + W +++G++     N+ WW+ R +YQGL PPV R++DDFDPG+K+HI   V YIRYF+  ++QFQ +E++C  SG+ GPLH+C+ Y SK AG  L ++L  G S+ WRE ++ +TG + I +++ L +F PL  WL   N K    +GW
Sbjct:   30 NDFYSEAQAKLFLQFYEQTAQVVLNEFMEATWNYVTNITKQNQKNMLQKEADRSQFMLYFSTRARMFRTDHFLNQDVKRMLR----KLQNIDKSALPTEDLLEYNRLLTYMETAYNRAEVCLDEGPCLTL-EPDLQEIMATSRDQKELLWAWQGWRDAVGRQLRPVFEDYVRLSNKAAQYNGYKDMGALWRS-KYESDTLEEDLEQLYKELQPLYLNLHAYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILDLVLP---------YPTKAPEDITAIMKIQHWRPEKMFEEANLFFTSMGMLPAPPAFWIKSMMEKPADGREVECHTSSWNFYKFNDFRVKKCTEVTLEDLLSVFHQMGHIQYFLQYQNLSVIYQEGASPAFEEAVGSVIALSVSSHKYLLARGLLSQPHQDSEEEVNFLLGIALEKIAFIPFSYLVDKFRWKIFDGTISKITYNQEWWNFRLKYQGLCPPVPRSDDDFDPGAKFHIPANVPYIRYFLGLILQFQLHEALCEASGHVGPLHQCDNYNSKVAGKILGDLLKLGSSRPWREVLQEVTGESNISTKAFLTYFKPLMDWLVTENVKQGDTLGW 610          

Query:  563 ELIHINNDISYIYNNAKPCFNK----CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATY---------GLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLI-SRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +L  I N +S IY+  K C  K    CL + E G+ ++  T  DY      W  WR   G++++ L+   + L+N  +R N + D   Y            +++  +       + +  I PLY+ LH YVR  L   YP     +G +PAH+ G++W + WTN++P+     QK + +       +       E++F  AE+F+ S+G+  MT  FW  SML++P D + V CH +A D  +G DFRIKMCT+  M +F T HHEMGHI+Y MAY+  P + R  AN GFHEA+G+ ++L+  TP+HL  IGL+ S   +    +I++L+  AL  V  LPF   ++ + W ++ G +P  +  K WW+++    G++ P+   E   DP S +H+S   S+IRY+   + QFQF E++C  + Y G LH+C+   S EAG KL++MLS G S+ W + ++ + GA  +  + LL +F PL+ WLK  N+  N  +GW
Sbjct:  115 QLNTILNTMSTIYSTGKVCNPKNPQECLLL-EPGLDEIMATSTDYNSRLWAWEGWRAEVGKQLRPLYEEYVVLKNEMARANNYNDYGDYWRGDYEAEGADGYNYNRNQLIEDVERTFAEIKPLYEHLHAYVRRKLMDTYPSYISPTGCLPAHLLGDMWGRFWTNLYPLTVPFAQKPNIDVTDAMMNQGWD---AERIFQEAEKFFVSVGLPHMTQGFWANSMLTEPADGRKVVCHPTAWDLGHG-DFRIKMCTKVTMDNFLTAHHEMGHIQYDMAYARQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLPSDFQEDSETEINFLLKQALTIVGTLPFTYMLEKWRWMVFRGEIPKEQWMKKWWEMKREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRYYTRTIYQFQFQEALCQAAKYNGSLHKCDISNSTEAGQKLLKMLSLGNSEPWTKALENVVGARNMDVKPLLNYFQPLFDWLKEQNR--NSFVGW 606          

Query:  557 VHELIHINNDISYIYNNAKPCF--NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKM--PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + E   I  D+   Y+ A  C+    CL + E  +  +  T + YE+L   W +WR+  G+ I  LF + ++L N  +  NG+ D      S  +E    +    +LY  + PLY  LH YVR  L++ Y  +  +  GPIPAH+ GN+WAQ W+NI+ ++       SA N   +ATE + K      ++F  A++F+ S+G+  +++EFW +SML KP D + V CH SA DF NG DFRIK CT  NM D    HHEMGHI+Y+M Y  LP  FR  AN GFHEAIGD +AL+V TP+HLH + L+S        DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV R++DDFDPGSK+H+   V YIRYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG  L + +  G S+ W E MK++TG   + + +++ +F PL +WL   N++    +GW
Sbjct:  743 LEEYNQILMDMETTYSIANVCYLNGTCLHL-EPDLTNVMATSRKYEELLWVWKSWRDKVGRAILPLFPKYVELSNKIAHLNGYADGGDSWRS-SYESKSLEQDLEQLYQELQPLYLNLHAYVRRSLHRHYGSQHINLDGPIPAHLLGNMWAQTWSNIYDLVAPFP---SAPNL--DATEAMIKQGWTPRRIFKEADDFFTSLGLLPVSEEFWNKSMLEKPGDGREVVCHASAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGGYEHDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQDDFDPGSKFHVPANVPYIRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADTMKMGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1227          

Query:  575 INNDISYIYNNAKPCF-NK---CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQK--LSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + N+++ IY+ +K C  NK   C  + E  +  +  + + Y KL   W +W +V G  +K L+     L N   +++G  D   Y  S  ++   F+ T   LY  + PLY  LH YVR  L++ Y  K+ +  GPIPAH+ G++WAQ W NI+ ++     K  L   N   +   N     V  MF +AEEF+ S+G+  M  EFW  SML KP D + V CH SA DF N  DFRIK CT   M   +T+HHEMGH++YY+ Y  L    R  AN GFHEAIGD +AL+V TP HLHKIGL+ RV +    DI+YL+  ALEK+AFLPF   +D + WG+++G  P S  N  WW  R +YQG+ PPV R E  FD G+K+HI  G  YIRYFVSF++QFQF++++C  +G++GPLH+C+ YQS +AG KL  +L  G S+ W+E +K + G+  + +++LL++F P+ +WL+  N++    +GW
Sbjct:  149 LQNNMNRIYSTSKVCLPNKTATCWSL-EPELTNILASSRSYAKLLFAWESWHDVVGIPLKPLYQDFTALSNEAYKQDGFSDTGAYWRS-AYDSPSFEETLEHLYHQLEPLYLNLHAYVRRALHRRYGDKYINLRGPIPAHLLGDMWAQSWDNIYDMVVPFPNKPNLDVTNTMVQKGWN-----VTHMFRVAEEFFTSMGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFFNRKDFRIKQCTRITMEQLSTVHHEMGHVQYYLQYKDLTVPLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDRVANDLESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGHTPPSRYNFDWWYFRTKYQGICPPVVRNETHFDAGAKFHIPSGTPYIRYFVSFILQFQFHQALCKEAGHQGPLHQCDIYQSTQAGAKLQRVLQAGYSRPWQEVLKEMVGSDTLDAQALLEYFQPVIRWLQEQNQRNGEVLGW 629          

Query:  506 RKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNK--CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKM--PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +K + +  ++   NE  + E   I  D+   Y+ A  C+    CL + E  +  +  T + YE+L   W +WR+  G+ I   F + +   N  ++ NG+ DA     S  +E DD +    KLY  + PLY  LH YVR  L++ Y  ++ +  GPIPAH+ GN+WAQ W+NI+ ++       S +     ATE + K      ++F  A+ F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  NM +    HHEMGHI+Y+M Y  LP  FR  AN GFHEAIGD +AL+V TP+HLH + L+S        DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV R++ DFDPGSK+H+   V YIRYF+SF+IQFQF+E++C  +G+ GPL++C+ YQSKEAG  L + +  G S+ W E MKI+TG   + + +++ +F PL +WL   N++    +GW
Sbjct:  728 KKVQNVDRAVLPPNE--LEEYNQILLDMETTYSVANVCYTNGTCLSL-EPDLTNIMATSRKYEELLWVWKSWRDKVGRAILPFFPKYVDFSNKIAKLNGYSDAGDSWRS-SYESDDLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPSID-----ATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTSVNMEELVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGSGYEHDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYIRYFISFIIQFQFHEALCRAAGHTGPLYKCDIYQSKEAGKLLADAMKLGYSKQWPEAMKIITGQPNMSASAIMNYFKPLTEWLVTENRRHGETLGW 1227          

Query:  506 RKFRLITASIRN---ENESLVHELIH--INNDISYIYNNAKPCF-NK---CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +K R I  S++     N  L   L +  + +++S IY+  K CF NK   C  + +  +  +  + ++Y K+   W  W +  G  ++ L+     L N   R++G  D   Y  S+ +E   F+ +   LY  + PLY  LH +VR  L++ Y  K+ +  GPIPAH+ G++WAQ W NI+ ++     K    N    +T          MF +AEEF+ S+G+  M  EFW  SML KP D + V CH SA DF N  DFRIK CT   M   +T+HHEMGH++YY+ Y  L    R  AN GFHEAIGD +AL+V TP HLHKIGL+ RV +    DI+YL+  ALEK+AFLPF   +D + WG+++G  P S  N  WW LR +YQG+ PPV R E  FD G+K+HI     YIRYFVSF++QFQF++++C  +G++GPLH+C+ YQS +AG KL ++L  G S+ W+E +K L G+  + + +L+++F P+ +WL+  N++    +GW
Sbjct:  121 QKLRRIIGSVQTLGPANLPLTQRLQYNSLLSNMSRIYSTGKVCFPNKTATCWSL-DPELTNILASSRNYAKVLFAWEGWHDAVGIPLRPLYQDFTALSNEAYRQDGFSDTGAYWRSW-YESPSFEESLEHLYHQVEPLYLNLHAFVRRALHRRYGDKYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDK---PNLDVTSTMVQKGWNATHMFRVAEEFFTSLGLSPMPPEFWAESMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDRVANDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNYDWWYLRTKYQGICPPVARNETHFDAGAKFHIPSVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSTKAGAKLQQVLQAGCSRPWQEVLKDLVGSDALDASALMEYFQPVSQWLQEQNQRNGEVLGW 629          

Query:  575 INNDISYIYNNAKPCFNK--CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCL-NKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQ------MFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            I +D+  IY+ AK C +   C ++ E  I  +  T + Y+KL   W  W N  G  ++  +   + L N   + +G ED  +Y  S+ ++   F+     LY  + PLY  LH +VR  L +++ P   +  GPIPAH+ GN+WAQQW NI+ ++           Y D+   +++   V Q      MF ++EEF+ S+G+ +M  EFWE+SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH++YY+ Y   P  FRG AN GFHEAIGD ++L+V TP HL KIGL+S   + +  +I+YL+  ALEK+AFLPF   +D + W +++G  P S  N  WW LR +YQG+  PV R E +FDPG+KYHI     YIRYFVSF++QFQF++++C  + + GPLH C+ Y SKEAG KL E+L  G S++W+E +  LTG  ++ + +LL++F P+  WL+  N K N  +GW
Sbjct:   43 ILSDMDKIYSTAKVCLDNGTCWDL-EPDISDIMATSRSYKKLLYAWEGWHNAAGNPLRAKYQEFVTLSNEAYQMDGFEDTGSYWRSW-YDSTTFEDDLEHLYNQLEPLYLNLHAFVRRKLYDRYGPKYINLKGPIPAHLLGNMWAQQWNNIYDLMVP---------YPDKPNLDVTNTMVNQGWNATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVQYYLQYKDQPVSFRGGANPGFHEAIGDVLSLSVSTPSHLQKIGLLSSAVEDEESNINYLLKMALEKIAFLPFGYLIDQWRWNVFSGRTPPSRYNYDWWYLRTKYQGICAPVSRNESNFDPGAKYHIPGNTPYIRYFVSFILQFQFHKALCQAANHTGPLHTCDIYMSKEAGAKLREVLKAGSSKSWQEILFNLTGTDKMDAGALLEYFSPVTTWLQEQNNKTNEVLGW 521          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLEL---KKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCF-NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCL-NKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            E YP   D+   E  AK +  + N  +    N +    ++Y+T+I   N E+   K       +       R+     ++      +  K  ++  +   E+E  + E   + +D+   Y+ AK C  N      +  +  +  T +DY +L   W  W + +G KIK  + R ++L N  +  NG+ D   Y  S  +E   F+    +LY  + PLY  LH YVR  L NK+        GPIPAH+ GN+WAQ W+NIF ++         +     A +     P + MF  ++ F+ S+G+  M  EFW++SM+ KP D + V CH SA DF N  DFRIK CT  NM D  T+HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP+HLH I L+ +V +++  DI+YLM+ AL+K+AFLPF   MD + W +++G +   E N+ WW+LR +YQGL PPV R+EDDFDPG+K+HI   V YIRYFVSF+IQFQF++++C  +G+ GPLH C+ YQSKEAG  L + +  G S+ W E M+++TG   + +E+L+ +F+PL  WL   N +    +GW
Sbjct:  532 EGYPEGIDKIVDEAQAKEFLSEYNSTAEVVWNAYTEASWEYNTNITDHNKEVMLEKNLAMSKHTIEYGMRARQFDPSDFQDETVTRILNKLSVLERAALPEDE--LKEYNTLLSDMETTYSVAKVCRENNTFHPLDPDLTDILATSRDYNELLFAWKGWWDASGAKIKDKYKRYVELSNKAAVLNGYTDNGAYWRSL-YETPTFEEDLERLYLQLQPLYLNLHAYVRRALYNKYGAEHISLKGPIPAHLLGNMWAQSWSNIFDLVMPFPDATKVD--ATPAMKQQGWTP-KMMFEESDRFFTSLGLIPMPQEFWDKSMIEKPADGREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYMDQPISFRDGANPGFHEAIGDVMALSVSTPKHLHSINLLDQVTENEESDINYLMSIALDKIAFLPFGYLMDQWRWKVFDGRIKEDEYNQQWWNLRLKYQGLCPPVPRSEDDFDPGAKFHIPANVPYIRYFVSFVIQFQFHQALCKAAGHTGPLHTCDIYQSKEAGKLLGDAMKLGFSKPWPEAMQLITGQPNMSAEALMSYFEPLMTWLVKKNTENGEVLGW 1119          

Query:  212 PSVFDSYYHMTDLESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRR---KFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKM--PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            P + D+Y    DLE+     D +  E      +D+  ++ +   N +A  +++Y+T+I  +  ++        S   LK   ++K F   +F++  ++R   K + +  ++    E   +  I ++ + +Y  +N       C+ + E  +  +  T + YE+L   W +WR+  G+ I   F + ++  N  ++ NG+ DA     S  +E D+ +    KLY  + PLY  LH YVR  L++ Y  ++ +  GPIPAH+ GN+WAQ W+NI+ ++       SA N   +ATE + K      ++F  A+ F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  NM D    HHEMGHI+Y+M Y  LP  FR  AN GFHEAIGD +AL+V TP+HL+ + L+S       +DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV R++ DFDPGSK+H+   V Y+RYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG  L + +  G S+ W E MK++TG   + + +++ +F PL +WL   N++    +GW
Sbjct:  635 PPLPDNYPEGIDLETDEAKADRFVEE------YDRTAQVLL---NEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPL-EPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGDSWRSL-YESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFP---SAPNI--DATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1226          

Query:  509 KFRLITASIRN---ENESLVHELIH--INNDISYIYNNAKPCF-NK---CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            K R I  SIR     N  L     +  + +++S IY+  K CF NK   C  + +  +  +  + + Y KL   W  W +  G  +K L+     + N   R++   D   +  S+ +E   F+ +   +Y  + PLY  LH YVR  L++ Y  K+ +  GPIPAH+ G++WAQ W NI+ ++     K    N    +T          MF ++EEF+ S+G+  M  EFW  SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH++YY+ Y  L    R  AN GFHEAIGD +AL+V TP HLHKIGL+  V +    DI+YL+  ALEK+AFLPF   +D + WG+++G  P S  N  WW LR +YQG+ PPV R E  FD G+K+HI     YIRYFVSF++QFQF++++C  +G++GPLH+C+ YQS +AG KL ++L  G S+ W+E +K L G+  + +++LL++F P+ +WL+  N++    +GW
Sbjct:  121 KLRRIIGSIRTLGPANLPLAQRQQYNSLLSNMSRIYSTGKVCFPNKTATCWSL-DPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAFWRSW-YESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDK---PNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGW 628          

Query:  584 DISYIYNNAKPCFN--KCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            D+   Y+ A  C     CL++ E  +  +  T + YE L   W  WR+  G+ I + + + ++L N  +R NG+ DA     S  +E    +    +L+  + PLY  LH YVR  L++ Y  +  +  GPIPAH+ GN+WAQ W+NI+ ++       S +    EA       P  +MF  A++F+ S+G+  +  EFW +SML KP D + V CH SA DF NG DFRIK CT  N+ D    HHEMGHI+Y+M Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + L+S    S   DI++LM  AL+K+AF+PF+  +D + W +++GS+     N+ WW LR +YQGL PPV RT+ DFDPG+K+HI   V YIRYFVSF+IQFQF+E++C  +G+ GPLH+C+ YQSKEAG +L   +  G S+ W E M+++TG   + + ++L +F PL  WL+  N+     +GW
Sbjct:  744 DMETTYSVATVCHTNGSCLQL-EPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM-YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLKQGWTP-RRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1219          

Query:  494 PELRRKFRLI-TASIRNENESLVHELIHINNDISYIYNNAKPCF-NK---CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            P+LRR    + T    N   +   +   + +++S IY+ AK C  NK   C  + +  +  +  + + Y  L   W  W N  G  +K L+     L N   +++G  D   Y  S+ +    F+     LY  + PLY  LH +VR  L++ Y  ++ +  GPIPAH+ G++WAQ W NI+ ++     K    N    +T          MF +AEEF+ S+ +  M  EFWE SML KP D + V CH SA DF N  DFRIK CT   M   +T+HHEMGHI+YY+ Y  LP   RG AN GFHEAIGD +AL+V TP HLHKIGL+  V +    DI+YL+  ALEK+AFLPF   +D + WG+++G  P S  N  WW LR +YQG+ PPV R E  FD G+K+H+     YIRYFVSF++QFQF+E++C  +GY+GPLH+C+ YQS +AG KL ++L  G S+ W+E +K + G   + ++ LLK+F P+ +WL+  N++    +GW
Sbjct:  113 PQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSL-DPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSW-YNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDK---PNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRGGANPGFHEAIGDVLALSVSTPAHLHKIGLLDNVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPNSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYQSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 621          

Query:  248 LESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLIS-RVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            LE YPNVC+ ++ E CA+ W  ++NEI IRN NR AN++FKY+T+IN  NL    + ++  + +  K+  K+KKF  K FKSP ++R   ++  S R  + S    LI I   I  IYN A PCF  C   GE GII++F   KDY+ LAGYW AWRN TG +I+ LF+ RM LEN  + ++G  D+A + L+ DF++ +F       +  I  LYKELHGYVR+CL+K+YP +F+KSGPIPAHI G+ W++ W N+F I++ C + +   + + E  EN+ K+ V +MF ++E FY S+GM  MTDEFW+RS+  K + K+++CH  +  F NGVDFRIKMCT K++ D T+I HEMGHI+Y+MAY +L   FR SANSGF E  GD + LA +TP +L KIGL+S  + + +  +I+YL+ +AL+ + F+PFA+S++ Y+  +YNGSV  +E+NK +WD+  + QG++PPV+RTE+ FD G+KYH++ G +Y R+  S+L Q+  +E+MCN+SGYKGPLH+C+F+ SKE G K +EM+  G ++NWR+TMKILTG T + S+SLL F+ PLY+WLK  NK+LN+  GW
Sbjct:    2 LEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHLKAKKFRLKFFKSPWVKRSLEMLKKSSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSLYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHEYDLRKEIDENIGKLTVHEMFKLSESFYSSLGMHNMTDEFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEYVNSVYNGSVGNNEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNVKTGW 591          

Query:  494 PELRRKFRLIT----ASIRNENESLVHELIHINNDISYIYNNAKPC-FNK------CLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPG-KFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSES--LLKFFDPLYKWLKFTNKKLNIPIGW 2014
            P +RR F+ ++    A++ N+    + ELI    D+  IY+ +K C FN       C    E  + ++    ++Y++LA  W AWR+V+G+++K  ++R ++L N  +  NG  D         +E D F+    +L+  I PLY++LH YVR  L   Y   K    GPIPAHI GN+WAQ W+ I   I    +K S +       +N+S +   ++F I+EEF+ S+G+  MTDEFWERS++ KP+D+ + CH SA DF +G DFRIK CT  NM DF   HHEMGHI+YY  Y+H P +FR  AN GFHEA+GD +AL+  TP+HL  IGL+  + + K  D+++L +TAL K+AFLPF   +D + WG+++G +  +E+N  WW+LR +YQG+ PPV+RTE+DFDPGSKYH+     Y+RYFVS +IQFQF++S+C  +G+ GPLH+C+ Y+SK+AG  L +ML  G S+ W E M I+TG    K ++  + ++F+PLY+WLK  NK     IGW
Sbjct:  100 PLIRRWFKKLSILGKAALPNDQLKELDELI---ADMKNIYSTSKVCPFNSKETDENCNLSLEPELTEILTKSRNYDELAYIWKAWRDVSGKRVKDKYIRFIELSNKAAELNGFRDTGELWRE-RYESDTFQQEIEQLWQQIRPLYEQLHAYVRRKLINIYGSDKIRHDGPIPAHILGNMWAQDWSGILQDITPYPEKPSVDITPKMIAKNMSAL---EIFKISEEFFTSVGLKAMTDEFWERSIIEKPKDREIVCHASAWDFCDGKDFRIKQCTSINMEDFIVTHHEMGHIQYYQQYAHQPCVFREGANPGFHEAVGDCLALSTSTPKHLQTIGLLDHIAEDKKGDVNFLFSTALSKLAFLPFGYLIDLWRWGIFSGDIKSTELNTKWWELRLKYQGICPPVERTENDFDPGSKYHVPGNTPYVRYFVSHVIQFQFHKSLCEAAGHVGPLHKCDIYKSKDAGKVLSQMLELGSSEIWNEAMNIMTGGVTNKMDAGPMFEYFEPLYQWLKEENK--GEVIGW 611          

Query:  506 RKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCF----NKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIR--------DCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGF----DIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            R+F+LIT      +++ V  + ++ + +  IY+  K C       CL + E  ++ L  T +DY++L   W +WR+VTG  I+ L+   +  +N  ++ENG  D   +    +FED +       L+  + PLY++LH YVR  L   Y  K+   +GPIPAH+ GN+WAQQW  I  +++        D    L  +NY            V++MF  AE F+ S+GM  MT EFWE+SM+ KP D + V CH SA DF N  D+RIKMCTE +  +   IHHEMGH++YYM YSH P I+R  AN+GFHEA+GDTIAL+V TPEHLHK+ L+  + D K      D+++LM  AL+K+AFLPF L +D + W ++ G    S  N+ WWDLR RYQG+ PPV R+E DFDPG+K+H+   V YIRYFVSFLIQFQF  ++C+ +G+ GP+H C+ YQS  AG KL +MLS G S+ W + M++LTG  EI   ++L++F PL  +L   NK  N  IGW
Sbjct:  124 RQFKLITMDASLRDDADVRRMSYLLSQMESIYDKGKVCRPHSEASCLPL-EPDLVNLMMTSRDYDELLWAWKSWRDVTGPPIRDLYREFVVFQNKAAKENGFADMGEFWRISNFEDKNLDKIVDGLFDQVKPLYQQLHAYVRRKLINQYGEKYVSPTGPIPAHLLGNMWAQQWDLILDLLQPYPNVPSVDVTSALKKQNYT-----------VQKMFKTAEAFFCSLGMDNMTKEFWEKSMVVKPTDGREVQCHASAEDFHNASDYRIKMCTEIDYDNLYVIHHEMGHVQYYMQYSHQPDIYRNGANAGFHEAVGDTIALSVATPEHLHKLKLLDDIGDDKELREKQDLNFLMKMALQKLAFLPFGLLIDKWRWDVFRGHTNASNYNQKWWDLRLRYQGIAPPVPRSELDFDPGAKFHVPANVPYIRYFVSFLIQFQFQRALCDAAGHTGPIHHCDIYQSTAAGEKLKKMLSLGSSRPWPDAMEVLTGQREIDPSAILEYFKPLQDFLVKENK--NEIIGW 630          

Query:  494 PELRRKFRLITASIRNE-NESLVHELIHINNDISYIYNNAKPCFN--------KCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            P+LRR+F+L+    R+  +   + EL     D++ IY ++K C +        KC    E  +I +     +Y++L   W  WR+  G  IKK +LR ++L N  +R NG  D         +E   F+     L+  + PLY+ LH YVR  L + +   K   +GPIPAH+ GN+WAQ W+N+   ++    K S +  Q    + ++ + + ++   +E+F+ S+G+  MT EFW +S+  KP+D+ + CH SA DF NG DFRIKMCTE NM      HHEMGH++YYM Y++ P  FR  AN GFHEAIGD +AL++ TP+HL  IGL+    + +  D+++LM+TAL+KVAFLPF   +D + W +++G +  S+ N  WW LR +YQG+ PPVKRTE DFDP +KYHI    +YIRYFVSF+IQFQF++++C+I+G+KGPLHRC+ Y SKEAG +L +ML  G S+ W   MK+LTG T++ +  +LK+F+PL KWLK  N+  +  IGW
Sbjct:  109 PQLRRQFKLLLILGRSALDPKKLRELNLCKADMANIYGSSKICLHVKGSKYDHKCNLALEPDLIDIMANSTNYKELLQVWKQWRDTVGPPIKKKYLRYVELSNEAARLNGFRDEGA-NWRKSYESVTFQRDIENLWRQVKPLYQHLHAYVRRRLIQLFGESKIRCNGPIPAHLLGNMWAQDWSNLIEYLKPFPTKPSFDVTQKMVAKKMTPLDIVKL---SEKFFTSLGLKAMTQEFWNKSIFEKPKDREMVCHPSAWDFCNGKDFRIKMCTEVNMDFLVITHHEMGHVQYYMQYANQPPTFRKGANEGFHEAIGDVMALSISTPKHLKTIGLLDNYTEDEENDLNFLMSTALKKVAFLPFGYIVDQWRWKVFSGKISPSQWNTEWWKLRLKYQGVCPPVKRTERDFDPAAKYHIPGDTAYIRYFVSFIIQFQFHQALCDIAGHKGPLHRCDIYNSKEAGKRLAQMLQMGSSRPWPVAMKVLTGKTKMDAGPILKYFEPLLKWLKEKNE--DEIIGW 619          

Query:  563 ELIHINNDISYIYNNAKPCFNKCLEVG------ESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDK-SGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSES--LLKFFDPLYKWLKFTNKKLNIPIGW 2014
            EL  I  D+  IY+ AK C  K L         E  + ++  T  DY++L   W  WRN TG+K+K  +++ ++L N  S+ NG  D         +E DDF+     L+  I P YK +H YVR  L + YP    K  GPIPAH+ GN+WAQ W NI P +    +K   +     +     KM +  MFT+++EF+ S+G+ KMT EFW  S++ KP+D+ + CH SA DF +G D RIKMCT  NM DF T+HHEMGHIEY++ Y+H PT+FR  AN GFHEAIGD +AL+V TP+H  K+GL+  V + K  DI+YLM  AL KV FLPFA  MD++ W L++G +   E+N  WW++R +YQGL PPVKRT +D D   KYH    V YIRYFV+ +IQFQF++++C+ +G++GPLH+C+ Y+S+ AG  L +M+  G S +W + M+I+T     K ++  LL++FDPL KWL   NK  N  +GW
Sbjct:  136 ELSEIVADMQDIYSRAKICSYKSLSKKDCNLSLEPELTEILATSTDYDELKHVWAGWRNATGKKMKDKYVKYVKLSNKASQLNGFSDTGMLWREV-YESDDFEEDIEALFQKIKPFYKHMHAYVRRKLIQRYPKHGIKPDGPIPAHLLGNMWAQTWGNILPEVMPYPKK---KELDITSVMKEKKMKIIDMFTMSDEFFASVGLKKMTSEFWNNSIIEKPRDREMVCHASAWDFYDGKDVRIKMCTRLNMNDFKTVHHEMGHIEYFLQYAHQPTVFRRGANPGFHEAIGDVMALSVSTPQHWVKVGLVDDVEEDKEADINYLMGVALNKVVFLPFAYVMDNWRWKLFSGEIKEDEMNSEWWNMRLKYQGLCPPVKRTNEDLDAACKYHTISDVKYIRYFVAHIIQFQFHKALCDAAGHEGPLHKCDIYRSENAGKLLRDMMRLGSSVHWEKAMQIITNGKTYKMDAKPLLEYFDPLIKWLHEKNK--NETVGW 622          

Query:  251 ESYP-NVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLE--LKKRFQRXXXXXXXXXXXXXXXXXX-XXXXXPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFN--KCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIR--------DCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            E YP +V D+   E  AK +  + N  +    N +    + Y+T+IN+ N +  L+K  +         L+ +       +      + +K   +  ++ ++++  + E  ++   +   Y+ AK C +   CL + +  + K+    +DY++L   W  WRN +G+++++ ++R ++L N+ +R NGH D   +  S  +E   F+     L+  + PLY  LH YVR  L K Y  K  +  GPIPAH+ GN+WAQ W+ I  ++R        D  Q + A+ +              +MF  +E F+ S+G+  M DEFW++SML KP D + V CH SA DF N  DFRIK CT  NM D  T+HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP+HLH IGL+ ++ ++    I++LM+ AL+K+AFLPF   MD + W +++G +  SE NK WW+LR +YQGL PPV RTE DFDPG+K+HI   V Y+RYFVSF++QFQF++++C+ +G+ GPLH C+ YQSKEAG  L +++  G S+ W E M ++TG  ++  + L+++F PL  WL+  N K    +GW
Sbjct:  621 EGYPEDVADKITDEAQAKQFLAEYNSTAETVWNAYTEASWSYNTNINEANKQNMLEKNLEMANHTKTYGLEARKYDTSDFQDSSVKRILKKLSDLERAVLSDDD--LKEYNNLLASMETTYSVAKVCKDDGTCLPL-DPDLNKIMAESRDYDELLFAWQGWRNASGRELRQSYVRYVELANLAARSNGHADNGAFWRSL-YETPTFEEDLEALWKDLQPLYLNLHSYVRRALFKKYGAKRINLKGPIPAHLLGNMWAQTWSGIMDLVRPYPNAAQVDVTQAMIAKGWD-----------ANRMFRESENFFTSVGLLPMPDEFWQKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVINMDDLITVHHEMGHVQYFLQYKDQPISFRDGANPGFHEAIGDVLALSVSTPKHLHTIGLLDKLEENAESTINFLMSIALDKIAFLPFGYLMDQWRWKVFDGRISSSEYNKEWWNLRLKYQGLCPPVTRTEVDFDPGAKFHIPANVPYVRYFVSFVVQFQFHKALCDTAGHTGPLHNCDIYQSKEAGKLLGDVMKLGFSKPWPEAMAMITGQPQMSVQPLMEYFQPLITWLEQENAKNGDVLGW 1209          

Query:  575 INNDISYIYNNAKPCFN--KCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            I + +  IY+ AK C    +C  + E  + ++    + Y+KL   W  W NV+G  +K L+   +QL N  S  +G +D   Y  S+ +E   F+     L+  + PLY+ LH +VR  L  FY P   +  GPIPAH+ GN+W+Q W NI+ ++     K + +       +N +      MF +AEEF+ S+G+ +M  +FW++SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGH+EYY+ Y   P  FR  AN GFHEA+GD ++L+V TP+HLH IGL+  +P+    DI+YL+  ALEK+AFLPF   +D + WG+++G  P    N  WW LR +YQG+ PPV+RTE+ FDPG+KYHI     YIRYFVSF++QFQF++ +C  +G+ GPLH C+ Y+S +AG  L ++L  G S+ W E ++   G  ++ + +L+++F P+  WL+  N+     +GW
Sbjct:  132 ILSQMDNIYSTAKVCPKPEECWAL-EPELKEILANSQSYKKLLYAWEGWHNVSGIPLKDLYPEFVQLSNNASVMDGFDDTGAYWRSW-YESPTFEQDLENLFKQLQPLYQNLHAFVRRKLYDFYGPKYINLKGPIPAHLLGNMWSQTWNNIYNMMIPFPDKPNVDVTNAMVEKNYN---ATHMFRVAEEFFTSLGLKEMPQKFWDKSMLEKPDDGREVVCHASAWDFYNREDFRIKQCTIVTMEQLFTVHHEMGHVEYYLQYKDQPVSFRRGANPGFHEAVGDVLSLSVSTPKHLHTIGLLDTLPNDNETDINYLLKMALEKIAFLPFGYLIDQWRWGVFSGRTPPERYNAEWWYLRTKYQGICPPVRRTEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHQKLCQEAGHTGPLHTCDIYRSTQAGAVLEKVLQAGSSKPWTEVLQEALGTNKMDAAALMEYFLPVTTWLEEQNRLTGETLGW 610          

Query:  566 LIHINNDISYIYNNAKPC-----FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLS---------FDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPV------EQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKV-VNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLI-SRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            L  + N++S IY+    C     F+ C +  E G+ ++    +DY +    W  WR   G+K++KL+     L+N  ++ N ++D   Y  +         + +  D+       +Y  I+PLYKELH YVR  L   YPG    +G +PAH+ G++W + WTN++P+         A  Y D+   ++S   V      E++F  AE+F+ S+ M  M   FW  SML+KP D   V CH +A D  N  DFRIKMCT+ NM DF T HHEMGH +Y MAY HLP + R  AN GFHEA+G+ ++L+  TP HL  +GL+ +   +    DI++L+  AL  VA LPF   ++ + W ++ G++P  +    WW+++    G+  P+ R E   DP + +H+S   S+IRYF   + QFQ  +++C  +G+ GPL++C+   S +AG KL +ML  G+S++W   ++ + G T + +  LL +F  LY+WLK  N+K N   GW
Sbjct:  115 LSKVLNEMSTIYSTGTVCKIDNPFD-C-QTLEPGLEEIMANSRDYYERLHVWEGWRVQVGKKMRKLYEEYADLKNEAAKLNNYKDYGDYWRANYETEDEPKYSYSRDELMRDVRSIYSEIMPLYKELHAYVRAKLQNTYPGHIASNGGLPAHLLGDMWGRFWTNLYPL---------AVPYPDKPDIDVSPAMVAQGWDEERLFKEAEKFFVSVNMSAMFPNFWTNSMLTKPTDGTKVVCHPTAWDMGNREDFRIKMCTKVNMDDFLTAHHEMGHNQYQMAYRHLPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPADFTEDMETDINFLLKQALTIVATLPFTYMLEEWRWQVFQGTIPKDQWMLRWWEMKRELVGVTEPLPRDESYCDPPALFHVSGDYSFIRYFTRTVYQFQLQDALCKEAGHTGPLYKCDITNSTDAGNKLRDMLELGRSKSWTRALEQVCGDTRMDARPLLSYFSTLYEWLKEENQKNNRASGW 608          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLI----TASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHED-AATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGK-FDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + YP   D+   E  A    ++ N  + +  + +    + Y+TDI +++ +L +      +   L   R +  + W +F+   +RR+ + I    TA++    E+ + E   I + +   Y+ AK C  +     +  I  +    ++Y++L  YW  WR+ +G+K+++ ++R ++L N  +  NG  D  A +  ++D E   F++   ++Y  + PLY  LH YVR  L++ Y  +  +  GPIPAH+ GN+WAQ W N+  ++       +A +          K   + MF +++ F+ S+GM  M  EFW++SML KP D + V CH SA DF N  DFRIK CT   M D  T+HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP+HL +IGL+  V D+   DI++L++ AL+K+AFLPF   MD + W +++G +P  + NK WW+LR +YQGL PPV RTEDDFDPGSK+HI   V Y RYFVSF+IQFQF E++C  +G KG LH+C+ Y+SK+AG KL +++  G S+ W+E M+++TG   + + +LLK+F PL  WL   N+K    +GW
Sbjct:  639 DDYPGNLDKITDETQAIALLEEYNTTAEKYWSEYNEASWTYNTDITEEHDKLVQEANLRMANHSLYFGRDALLYDWSNFQDEGVRRQLKKISQIGTAALP---ETELKEYNEIVSRMETAYSVAKVCRGETCIPLDPDITAIMAESRNYDELLYYWQGWRDASGRKMREDYVRYVELSNKAAIANGFPDNGAQWRSAYDTET--FEADLERIYEELKPLYLNLHAYVRRKLHQHYGDEHVNLKGPIPAHLLGNMWAQSWNNLNSLVAPFP---NAPSVDATPAMQAQKWTPKMMFNVSDVFFTSLGMIPMPREFWDKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVVTMDDLVTVHHEMGHVQYFLQYKEQPVPFRDGANPGFHEAIGDVMALSVATPKHLKEIGLLETVEDNSESDINFLLSMALDKIAFLPFGFLMDQWRWKVFDGRIPTEDYNKEWWNLRMKYQGLCPPVARTEDDFDPGSKFHIPASVPYDRYFVSFVIQFQFQEALCAAAGQKGDLHKCDIYKSKDAGDKLAKVMQLGSSRRWQEAMEMITGQQNMSAAALLKYFKPLTDWLVKENQKNGEVLGW 1225          

Query:  581 NDISYIYNNAKPC------FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQ------MFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKG---FDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +D+  IY+  K C         C  + +  I  +  T + Y+KL  YW  W NV G+ +   + R ++L N  S+ +   D   Y  S+ +E   F+    ++Y  + PLY  LH YVR  L++ Y  KF +  GPIPAH+ GN+W+QQW NIF ++           Y  + + +++   VEQ      MF  +E+F++ +G+ +M  EFW  SML KP D + V CH SA DF N  DFRIK CT   M    T+HHEMGHIEYY+ Y      FRG AN GFHEAIGD ++L+V TP HL  IGL+   PD  G    DI+YLM  ALEK+AFLPF   +D + W +++G  P    N+ WW LR +YQG+ P V R   DFD G+K+HI     YIRYFVSF+IQFQF +++C  +  KGPL++C+  +++ AG  L + +  G S+ W E MK +TG  ++ +  L+++F P+  WL+  N  +N  +GW
Sbjct:  149 SDMDAIYSTGKVCKPGQTSGTDCAPL-DPTITDILATSRSYKKLLYYWEGWHNVVGRPLHSKYARFVELSNAASQLDDFADTGEYWRSW-YESATFRDDLERIYEELKPLYLNLHAYVRRKLHQHYGEKFVNLKGPIPAHLLGNMWSQQWNNIFDMVVP---------YPGKTSVDVTDTMVEQGWNATHMFRTSEDFFKDLGLLEMPPEFWSGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTIPTMEQLFTVHHEMGHIEYYLQYKDQHVSFRGGANPGFHEAIGDVLSLSVSTPTHLKTIGLLG--PDYVGDKESDINYLMKMALEKIAFLPFGYLIDLWRWDVFSGKTPPERYNQDWWYLRTKYQGICPGVPRKSTDFDAGAKFHIPGNTPYIRYFVSFIIQFQFQKALCTAAQDKGPLYKCDIDKNQAAGNLLRKAMQMGSSRPWTEVMKEMTGTDKMSALPLIEYFKPVIDWLEKEN--VNETLGW 628          

Query:  500 LRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPC------FNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQ------MFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLI--SRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLR 1633
            L R+ R++ ++  N + +   EL  +   +   Y+    C         C  + E  +  +  T + Y +L  YW  WR   G+ ++  +   +QL N  SR +G  D   +  S  +E + F++   +LY  + PLY  +H YVR  L++ Y  +  +  GPIPAH+ G++WAQQW  I+ ++           Y  +   +++   VEQ      MF ++EEF+ S+G+ +M  EFW  SML KP D + V CH SA DF N  DFRIK CT   M D    HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP HL KIGL+  S V D    DI++L+  AL K+AFLPF   +D + W +++G  P    N  WW LR
Sbjct:   25 LLREMRIMGSA--NLHPAAREELNRVILQMQTTYSTGAVCKPGHSSGPDCFPL-EPELDHIMATSRSYTQLLYYWEGWRTDVGRPLRAPYAHFVQLSNEASRADGFADTGEFWRSV-YETETFRADLERLYDELRPLYLHMHAYVRRRLHRRYGERLVNLRGPIPAHLLGDMWAQQWQGIYDLV---------VPYPGKTRVDVTSAMVEQGWNTTHMFRVSEEFFTSLGLMEMPPEFWNGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTSVTMTDLVRAHHEMGHVQYFLQYKEQPVPFRRGANPGFHEAIGDVMALSVATPRHLKKIGLLEPSYVEDPAESDINFLLWMALGKIAFLPFGFLVDQWRWDVFSGHTPPGRYNHDWWHLR 405          

Query:  644 ESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQ------MFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLI 1465
            E  +  +  T + Y +L  YW  WR   G+ ++  +   +QL N  SR +G  D   +  S  +E + F++   +LY  + PLY  +H YVR  L++ Y  +  +  GPIPAH+ G++WAQQW  I+ ++           Y  +   +++   VEQ      MF ++EEF+ S+G+ +M  EFW  SML KP D + V CH SA DF N  DFRIK CT   M D    HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP HL KIGL+
Sbjct:  132 EPELDHIMATSRSYTQLLYYWEGWRTDVGRPLRAPYAHFVQLSNEASRADGFADTGEFWRSV-YETETFRADLERLYDELRPLYLHMHAYVRRRLHRRYGERLVNLRGPIPAHLLGDMWAQQWQGIYDLVVP---------YPGKTRVDVTSAMVEQGWNTTHMFRVSEEFFTSLGLMEMPPEFWNGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTSVTMTDLVRAHHEMGHVQYFLQYKEQPVPFRRGANPGFHEAIGDVMALSVATPRHLKKIGLL 403          

Query:  497 ELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAK-PCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + +R+ +LI AS   +N + +     +N+ +  IY++ K    N  +      + K+    +DYE+L   W  WR+  G  I+ L+ + + + N G++ENG +D   Y  S  +E ++ +  A  LY  + PLY+ELH YVRY L++ Y  +      IPAH+FGN+WAQ W NI+ ++   G + S +  ++   +  +++   +M  +AE F+ SIG+  +   F+ RSM+ KP+D+ V CH SA DF    D RIK CT        T HHE+GHI+Y++ Y+H P  +R  AN GFHEA+GDT++L+V TP HLH+IGL+  V ++   DI+ LM  AL KVAFLPF   +D + W ++ G +     N+ WW+LR +YQG+ PPV RTE+DFDPG+KYHI     YIRYFVS++IQFQF+++ C  +G+ GPLH+C+ Y S  AG KL  ML  GKS+ W + +K +TG  E+    L ++F PL  W+K    K   PIGW
Sbjct:   95 DTKRQIKLIAASASPKNPADIKRKSELNSQMDKIYSSGKVKDANGEMLSLNPDLYKILAESRDYERLLFVWKGWRDAVGPAIRPLYQQFVDISNKGAKENGWKDNGEYWRS-SYEVENLERIAEGLYSDLKPLYQELHAYVRYKLSQQY-SQVKSGDAIPAHLFGNMWAQSWANIYDLVEPYGNQSSLDVTRNMVKQGYTEL---RMVQLAESFFTSIGLDPLPQSFYNRSMIVKPKDRGVVCHASAWDFLISRDVRIKQCTTITHDSLVTTHHELGHIQYFLQYAHQPYEYRTGANPGFHEAVGDTLSLSVDTPAHLHRIGLLDAVSNNTESDINALMKMALSKVAFLPFGFLIDQWRWRVFRGEITPQNYNRKWWELRTKYQGIKPPVCRTENDFDPGAKYHIPANTPYIRYFVSYVIQFQFHKAACEAAGHTGPLHKCSIYNSTAAGGKLGAMLKLGKSKPWPQALKAMTGTEEMDVGPLTEYFKPLITWMKAQRAKHGYPIGW 596          

Query:  497 ELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVG-ESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFT------IAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + RR+ +++T +  + ++ +   L  +   +  IY + K       ++  +  + K+    +DYE+L   W  WR+ TG +++ L+ + ++L N G++ENG  D   +  S+ +E D+ +S+   LY  + PLY+ELH YVRY L+K Y  +   +GPIPAH+FGN+WAQ W NI+ II         E Y+++ + +++K  V Q +T      +AE F+ SIG+  +   F+E+SM+ KP+ + V CH SA DF    D RIK CT        T HHE+GHI+YY+ Y   P  +R  AN GFHEA+GDT++L+V TP HL  IGL+  V +    DI+ LM  AL KVAFLPF   +D + W +++G +     N+ WW LR +YQG+ PPV RTE+DFDPG+KYHI     YIRYFVSF++QFQF+++ C  +G++GPLH+C+ Y S EAG KL +MLS GKS+ W   ++ +TG  ++   SL ++F PL  WLK   ++    IGW
Sbjct:  562 DTRRQIKMVTETASSSDKDVQKTLNDVEGKMDQIYGSGKVIDTDGSKLSLDPHLYKILSNSRDYERLKFVWKGWRDATGPELRPLYKQFVELANKGAKENGWADNGEWWRSW-YEIDNLESSVEALYEDLRPLYEELHAYVRYKLSKKY-SQVKPTGPIPAHVFGNMWAQSWVNIYDII---------EPYENQPSLDVTKTMVAQNYTQLRMVQLAESFFTSIGLKALPMSFYEKSMIVKPEGREVQCHASAWDFKINRDVRIKQCTTITHNYLVTTHHELGHIQYYLQYWDQPFEYRTGANPGFHEAVGDTLSLSVDTPTHLKLIGLLDAVSNDSKSDINALMKMALRKVAFLPFGFLIDQWRWKVFSGDITSDNYNREWWKLRTKYQGIKPPVCRTENDFDPGAKYHIPGNTPYIRYFVSFVLQFQFHKAACEAAGHQGPLHKCSIYNSTEAGKKLGDMLSLGKSKPWPLALEQMTGTRKMDVSSLKEYFKPLSDWLKSQRQEYKYTIGW 1063          

Query:  581 NDISYIYNNAK---PCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDF----SNG-VDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            ++++ IY++AK   P     L +    + +L    ++  +L   W  WR VTG K++ LF   + L N G+++NG ++   Y     +E  + +     ++  +  LY ELH YVR  L++ YP     S  IPAH+ GN+WAQ W NI+P++     K S +  ++   +N + +   +M  +AE F+ SIG  K+   F+ +SM  KP+D+ V CH +A DF    S G  D RIK CTE    D    HHEMGHI Y++ Y   P I+R  AN  FHEA+GDTIAL+V TP HL K+ L+    + K  +I+ LM  AL K+AFLPF   ++ + W +Y G +  SE NK WW+LR ++QG+ PP+ R E  FDPGSK+HI+    YI+YF+S ++QFQ ++++C+I+G   PLH+C+ Y S +AG KL  ML  G+S+ WR+T++  TG+ ++    L ++F PLY+WL     +    IGW
Sbjct:    8 SEMTEIYSSAKVTNPAIGTNLSLNPQ-LTELMANSRNSPELLAAWRDWRQVTGPKMRPLFKDCVTLANQGAKDNGFQNMYEYQTHL-YELPNLEEYIDGIWQELKVLYLELHAYVRQRLSEQYPHVLS-SQAIPAHLLGNMWAQNWVNIYPLVEPYSGKPSLDVTKNLRQQNYTAV---KMVQLAEAFFRSIGFEKLPGSFYSKSMFEKPEDREVLCHAAALDFFEKNSKGEKDVRIKQCTEITHQDLIITHHEMGHIYYFLKYWDQPYIYRDGANPAFHEALGDTIALSVDTPRHLVKVKLLDEYMEDKEAEINALMKMALSKIAFLPFGYLLEKWRWQVYTGEIDSSEYNKKWWELRVKHQGVRPPISRDETTFDPGSKFHIAANARYIQYFLSRILQFQLHKTVCDIAGINEPLHKCSIYNSTKAGQKLSAMLEMGRSKPWRDTLEAFTGSRDMSVNPLKEYFHPLYQWLVEQRCQNKYKIGW 487          

Query:  581 NDISYIYNNAKPCFN-----KCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQD----EATENLSKM--PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
             +++ IY+  K C N      C+ + +  +  L    ++ ++L   W  WR+     ++ +F + + L N G+R++G  D   +        +DF +   KL+  + PLYKELH YVR+ L K Y G    SGPIPAH+ GN+WAQ W  I+ ++         + Y D    + T +L K     E+MF +A+ F+ SIG+  M   FW +SML KP +K V CH SA DF    D RIKMCT     D  TIHHEMGH EY++AY   P  +R  AN GFHEAIGDTIAL+V TP+HL+ +GL+  +P      I++LM  AL  VA LPF   +D + W +  G +  S  N  WW +R  YQG+ PPV R E DFDPG+K+HI     YI YFVS ++QFQF+ ++CN+  + GPLH C+ YQSKEAG K  EML+ G+S+ W +T+  LTG  E+ ++ LL++F PL KWL     K N  +GW
Sbjct:    3 TNMTEIYSTGKVCLNITRNNTCMSL-DPDLGNLMSRSRNQDELVWAWRGWRDAVAPPVRGMFQQMVDLLNKGARQHGLGDYGHFERGEYEMGNDFTAVIKKLWTDVKPLYKELHAYVRFQLKKKYAG-MSGSGPIPAHLLGNMWAQNWDGIYDMV---------QPYPDATPLDVTPSLIKQHYTPEKMFKLAQSFFVSIGLDPMPKSFWNKSMLRKPGNKSVVCHASAFDFLKD-DVRIKMCTRLKQEDLITIHHEMGHCEYFLAYKDQPYAYRNGANPGFHEAIGDTIALSVVTPKHLNSVGLLYTLPKGDEASINFLMTQALSHVAPLPFTYLVDQWRWKVLAGEISPSNYNSAWWRMRTLYQGVKPPVARNESDFDPGAKFHIVSNSPYIGYFVSLILQFQFHRALCNLVKHTGPLHECSIYQSKEAGKKFKEMLAAGRSRPWPQTLFKLTGEREMSADPLLEYFAPLRKWLFNYRIKNNYTLGW 479          

Query:  581 NDISYIYNNAKPCFN-----KCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQD----EATENLSKM--PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
             +++ IY+  K C N      C+ + +  +  L    ++ ++L   W  WR+     ++ +F + + L N G+R++G  D   +        +DF +   KL+  + PLYKELH YVR+ L K Y G    SGPIPAH+ GN+WAQ W  I+ ++         + Y D    + T +L K     E+MF +A+ F+ SIG+  M   FW +SML KP +K V CH SA DFS      IKMCT     D  TIHHEMGH EY++AY   P  +R  AN GFHEAIGDTIAL+V TP+HL+ +GL+  +P      I++LM  AL  VA LPF   +D + W +  G +  S  N  WW +R  YQG+ PPV R E DFDPG+K+HI     YI YFVS ++QFQF+ ++CN++ + GPLH C+ YQSKEAG K  EML+ G+S+ W +T+  LTG  E+ ++ LL++F PL KWL     K    +GW
Sbjct:    3 TNMTEIYSTGKVCLNITRNNTCMSL-DPDLGNLMSRSRNQDELVWAWRGWRDAVAPPVRGMFQQMVDLLNKGARQHGLGDYGHFERGEYEMGNDFTAVIKKLWTDVKPLYKELHAYVRFQLKKKYAG-MSGSGPIPAHLLGNMWAQNWDGIYDMV---------QPYPDATPLDVTPSLIKQHYTPEKMFKLAQSFFVSIGLDPMPKSFWNKSMLRKPGNKSVVCHASAFDFSKMTSGAIKMCTRLKQEDLITIHHEMGHCEYFLAYKDQPYAYRNGANPGFHEAIGDTIALSVVTPKHLNSVGLLYTLPKGDEASINFLMTQALSHVAPLPFTYLVDQWRWKVLAGEISPSNYNSAWWRMRTLYQGVKPPVARNESDFDPGAKFHIVSNSPYIGYFVSLILQFQFHRALCNLAKHTGPLHECSIYQSKEAGKKFKEMLAAGRSRVWPQTLFKLTGEREMSADPLLEYFAPLRKWLFNYRIKNKYTLGW 480          

Query:  959 SGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKM--PVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            SGPIPAH+ GN+WAQ W  I+ +++        +      T +L K     E+MF +A+ F+ SIG+  M   FW +SML KP +K V CH SA DF    D RIKMCT     D  TIHHEMGH EY++AY   P  +R  AN GFHEAIGDTIAL+V TP+HL+ +GL+  +P      I++LM  AL  VA LPF                             YR+  +   +    D  D      I   + Y RYFVS ++QFQF+ ++CN+  + GPLH C+ YQSKEAG K  EML+ G+S+ W +T+  LTG  E+ ++ LL++F PL KWL     K N  +GW
Sbjct:    4 SGPIPAHLLGNMWAQNWDGIYDMVQPYPDATPLD-----VTPSLIKQHYTPEKMFKLAQSFFVSIGLDPMPKSFWNKSMLRKPGNKSVVCHASAFDFLKD-DVRIKMCTRLKQEDLITIHHEMGHCEYFLAYKDQPYAYRNGANPGFHEAIGDTIALSVVTPKHLNSVGLLYTLPKGDEASINFLMTQALSHVAPLPFTFDF-------------------------YRHDFIDITLFHRYDFID---MTFIDMTLLY-RYFVSLILQFQFHRALCNLVKHTGPLHECSIYQSKEAGKKFKEMLAAGRSRPWPQTLFKLTGEREMSADPLLEYFAPLRKWLFNYRIKNNYTLGW 322          

Query:  677 KDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            + Y  L   W AW N  G  +KKL+ R ++L N  SR +G  D   +  S+D + + F+     LY  I PLY  LH +VR  L   Y  K+ +  GPIPAH+ GN+WAQ W NI+ ++     K++ +   +   +  +      MF +AEEF+ S+G+ +M  EFWE SM+ KP D+ V CH SA DF N  DFRIK CT+  M +F T+HHEMGHI+YY+ Y + P  FR  AN GFHEAIGD +AL+V TP+HLHKI L+      +  ++++L+  AL+K+AFLPF   +D + WG+++   P    N  WW LR +YQG+ PP++RTE+ FDPG+K+HI     YIRYFVSF++QFQ +E +C  + + GPLH C+ Y+SKEAG  L ++L  G S+ W E ++   G  +I + SL+K+FDP+ +WL+  N  +N  +GW
Sbjct:   94 RSYNLLLFTWEAWHNTAGVPLKKLYSRFVELSNKASRADGFADTGAWWRSWDDDSETFEQDMDNLYKTIQPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIPFPGKVNVDVTDEMVRQGYN---ATHMFRVAEEFFTSLGLMEMPKEFWEGSMIVKPNDRDVVCHASAWDFYNRKDFRIKQCTKVTMDEFFTVHHEMGHIQYYLQYKNQPVGFRDGANPGFHEAIGDLMALSVSTPKHLHKINLMKSAESDEETNLNFLLNMALQKIAFLPFGYLVDLWRWGVFSEKTPPERYNADWWYLRTKYQGICPPIRRTEEQFDPGAKFHIPNNTPYIRYFVSFILQFQLHEKLCEAANHTGPLHTCDIYRSKEAGTILKKILEPGSSRPWPELLQETIGTNKIDASSLMKYFDPVIRWLEKQN--VNETLGW 535          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRN-ENESLVHELIHINNDISYIYNNAKPCFNKCLEVG-----ESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNI--FPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            E YP   ++   E  AK   D+ N  +    N +    +KY+TDI   N +         S   LK   K++++    F+ P ++R    + A + + E  +L  E +   N +             C E G     +  + K+    +DY +L   W  WR+  G+ +++ + R ++L N  +  +G+ D      S  +E   F+     L+  + PLY+ +H YVR  L K Y P   +  GPIPAH+ GN+WAQ W+ I  F I      ++ A         N ++M     F  ++ F+ S+G+  M +EFWE+SML KP D + V CH SA DF N  DFRIK CT   M D  T+HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V ++   DI++LM+ AL+K+AFLPF   MD + W +++G +P +E NK WW+LR +YQGL PPV RTE+DFDPG+K+HI   V Y+RYFVSF+IQFQF++++C  + + GPLH C+ YQSKEAG  L +++  G S+ W E M I+TG +++ ++ L+++F+PL +WL+  N+     IGW
Sbjct:  545 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKR----VIAKLSDIERAALPPEELEEYNTLLSNMETKYSVAEVCREDGRCHPLDPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGAMWRSL-YETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIPYPGATQVDATPAMLAQGWNATRM-----FQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYESDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1132          

Query:  575 INNDISYIYNNAK--PCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            I + +  IY+ AK  P  N    + E  +  +  T + Y+KL   W  W N +G  +KKL+   ++L N  S+ +G  D      S+ +E + F+     LY  I PLY  LH +VR  L   Y  K+ +  GPIPAH+ GN+WAQ W NI+ ++     K + +   +   +  +      MF ++EEF+ S+G+ +M  EFWE SM+ KP D+ V CH SA DF N  DFRIK CT   M    T+HHEMGHI+YY+ Y   P  FR  AN GFHEAIGD ++L+V TP+HLH I L+         DI+YL+  ALEK+AFLPF   +D + WG++NG  P  + N  WW LR ++QG+ PP KR+E+ FDPG+KYHI     YIRYFVSF++QFQF+E +C  + + GPLH C+ Y+S EAG  L ++L  G S+ W E ++   G  E+ + SLLK+F+P+ KWL+  N  +N  +GW
Sbjct:   59 ILSTMDSIYSTAKVYPQPNVSWSL-EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGADWRSW-YESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIPFPNKPNLDVTDEMVRQGYN---ATHMFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 534          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRN-ENESLVHELIHINNDISYIYNNAKPCFNKCLEVG-----ESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNI--FPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            E YP   ++   E  AK   D+ N  +    N +    +KY+TDI   N +         S   LK   K++++    F+ P ++R    + A + + E  +L  E +   N +             C E G     +  + K+    +DY +L   W  WR+  G+ +++ + R ++L N  +  +G+ D      S  +E   F+     L+  + PLY+ +H YVR  L K Y P   +  GPIPAH+ GN+WAQ W+ I  F I      ++ A         N ++M     F  ++ F+ S+G+  M +EFWE+SML KP D + V CH SA DF N  DFRIK CT   M D  T+HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V ++   DI++LM+ AL+K+AFLPF   MD + W +++G +P +E NK WW+LR +YQGL PPV RTE+DFDPG+K+HI   V Y+RYFVSF+IQFQF++++C  + + GPLH C+ YQSKEAG  L +++  G S+ W E M I+TG +++ ++ L+++F+PL +WL+  N+     IGW
Sbjct:  545 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKR----VIAKLSDIERAALPPEELEEYNTLLSNMETKYSVAEVCREDGRCHPLDPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGAMWRSL-YETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIPYPGATQVDATPAMLAQGWNATRM-----FQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYESDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1132          

Query:  575 INNDISYIYNNAK--PCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            I + +  IY+ AK  P  N    + E  +  +  T + Y+KL   W  W N +G  +KKL+   ++L N  S+ +G  D      S+ +E + F+     LY  I PLY  LH +VR  L   Y  K+ +  GPIPAH+ GN+WAQ W NI+ ++     K + +   +   +  +      MF ++EEF+ S+G+ +M  EFWE SM+ KP D+ V CH SA DF N  DFRIK CT   M    T+HHEMGHI+YY+ Y   P  FR  AN GFHEAIGD ++L+V TP+HLH I L+         DI+YL+  ALEK+AFLPF   +D + WG++NG  P  + N  WW LR ++QG+ PP KR+E+ FDPG+KYHI     YIRYFVSF++QFQF+E +C  + + GPLH C+ Y+S EAG  L ++L  G S+ W E ++   G  E+ + SLLK+F+P+ KWL+  N  +N  +GW
Sbjct:   59 ILSTMDSIYSTAKVYPQPNVSWSL-EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGADWRSW-YESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIPFPNKPNLDVTDEMVRQGYN---ATHMFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 534          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRN-ENESLVHELIHINNDISYIYNNAKPCFNKCLEVG-----ESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNI--FPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            E YP   ++   E  AK   D+ N  +    N +    +KY+TDI   N +         S   LK   K++++    F+ P ++R    + A + + E  +L  E +   N +             C E G     +  + K+    +DY +L   W  WR+  G+ +++ + R ++L N  +  +G+ D      S  +E   F+     L+  + PLY+ +H YVR  L K Y P   +  GPIPAH+ GN+WAQ W+ I  F I      ++ A         N ++M     F  ++ F+ S+G+  M +EFWE+SML KP D + V CH SA DF N  DFRIK CT   M D  T+HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V ++   DI++LM+ AL+K+AFLPF   MD + W +++G +P +E NK WW+LR +YQGL PPV RTE+DFDPG+K+HI   V Y+RYFVSF+IQFQF++++C  + + GPLH C+ YQSKEAG  L +++  G S+ W E M I+TG +++ ++ L+++F+PL +WL+  N+     IGW
Sbjct:  625 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKR----VIAKLSDIERAALPPEELEEYNTLLSNMETKYSVAEVCREDGRCHPLDPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGAMWRSL-YETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIPYPGATQVDATPAMLAQGWNATRM-----FQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYESDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1212          

Query:  575 INNDISYIYNNAK--PCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            I + +  IY+ AK  P  N    + E  +  +  T + Y+KL   W  W N +G  +KKL+   ++L N  S+ +G  D      S+ +E + F+     LY  I PLY  LH +VR  L   Y  K+ +  GPIPAH+ GN+WAQ W NI+ ++     K + +   +   +  +      MF ++EEF+ S+G+ +M  EFWE SM+ KP D+ V CH SA DF N  DFRIK CT   M    T+HHEMGHI+YY+ Y   P  FR  AN GFHEAIGD ++L+V TP+HLH I L+         DI+YL+  ALEK+AFLPF   +D + WG++NG  P  + N  WW LR ++QG+ PP KR+E+ FDPG+KYHI     YIRYFVSF++QFQF+E +C  + + GPLH C+ Y+S EAG  L ++L  G S+ W E ++   G  E+ + SLLK+F+P+ KWL+  N  +N  +GW
Sbjct:  139 ILSTMDSIYSTAKVYPQPNVSWSL-EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGADWRSW-YESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIPFPNKPNLDVTDEMVRQGYN---ATHMFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 614          

Query:  251 ESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRN-ENESLVHELIHINNDISYIYNNAKPCFNKCLEVG-----ESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFY-PGKFDKSGPIPAHIFGNVWAQQWTNI--FPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQD-KVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            E YP   ++   E  AK   D+ N  +    N +    +KY+TDI   N +         S   LK   K++++    F+ P ++R    + A + + E  +L  E +   N +             C E G     +  + K+    +DY +L   W  WR+  G+ +++ + R ++L N  +  +G+ D      S  +E   F+     L+  + PLY+ +H YVR  L K Y P   +  GPIPAH+ GN+WAQ W+ I  F I      ++ A         N ++M     F  ++ F+ S+G+  M +EFWE+SML KP D + V CH SA DF N  DFRIK CT   M D  T+HHEMGH++Y++ Y   P  FR  AN GFHEAIGD +AL+V TP+HL  IGL+ +V ++   DI++LM+ AL+K+AFLPF   MD + W +++G +P +E NK WW+LR +YQGL PPV RTE+DFDPG+K+HI   V Y+RYFVSF+IQFQF++++C  + + GPLH C+ YQSKEAG  L +++  G S+ W E M I+TG +++ ++ L+++F+PL +WL+  N+     IGW
Sbjct:  623 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKR----VIAKLSDIERAALPPEELEEYNTLLSNMETKYSVAEVCREDGRCHPLDPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGAMWRSL-YETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIPYPGATQVDATPAMLAQGWNATRM-----FQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYESDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1210          

Query:  575 INNDISYIYNNAK--PCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKF-DKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            I + +  IY+ AK  P  N    + E  +  +  T + Y+KL   W  W N +G  +KKL+   ++L N  S+ +G  D      S+ +E + F+     LY  I PLY  LH +VR  L   Y  K+ +  GPIPAH+ GN+WAQ W NI+ ++     K + +   +   +  +      MF ++EEF+ S+G+ +M  EFWE SM+ KP D+ V CH SA DF N  DFRIK CT   M    T+HHEMGHI+YY+ Y   P  FR  AN GFHEAIGD ++L+V TP+HLH I L+         DI+YL+  ALEK+AFLPF   +D + WG++NG  P  + N  WW LR ++QG+ PP KR+E+ FDPG+KYHI     YIRYFVSF++QFQF+E +C  + + GPLH C+ Y+S EAG  L ++L  G S+ W E ++   G  E+ + SLLK+F+P+ KWL+  N  +N  +GW
Sbjct:  137 ILSTMDSIYSTAKVYPQPNVSWSL-EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGADWRSW-YESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIPFPNKPNLDVTDEMVRQGYN---ATHMFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 612          

Query:   92 MVFKXXXXXXXXXXXXXXRDRFFSKTKNEIDFDDEFQALEPSVFDSYYHMTDLESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            MVFKLTLLIVILIQSLQSRDRFFSKTKNEIDFDDEFQALEPSVFDSYYHMTDLE YPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRIGSKIGLKLKRKSKKFHWKSFKSPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKN+VDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW
Sbjct:    1 MVFKLTLLIVILIQSLQSRDRFFSKTKNEIDFDDEFQALEPSVFDSYYHMTDLEGYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRIGSKIGLKLKRKSKKFHWKSFKSPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNIVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 641          

Query:  218 VFDSYYHMTDLESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +FDSY+++T+LE YP VC+EY++E CAK W  K+NEI+IRN NR+AN++++Y ++INK NLEL K+FQ I  K+G  ++ K+KKF WK F SP +R+    ++ ++R+++E++   L+ + + I YIYNN KPCF  CL  GE  II LFK EKDY+KL GYW AWRNVTG +I+ LF+++++LEN+G+RENG  D A++ L  DFE+++FK T ++LY  ILPLYKELH +VRYCL K+YPGKFDK+GPIPAHIFGNVW+QQWTNIF I++ C +     ++ ++A+  L K+ V +MF +AEEFY SIG+FKMT+EFWERS++ +   ++++CHGSAHDF+NGVD+RI MCT+K++ DFTTIHHEMGHIEY+MAYS LPT +R SANSGFHEAIGDTIALAVKTPEHLHKIGL+  +P SK FDI+YLM +ALEKVAFLPFAL MDSYIW +YNG++P S++N++WWDL  +YQG+ PPV+R+E DFD G+KYHI+F V YIRYF+SF+IQFQFYESMC++SGYKGPLHRC+FYQS +AG KL+EML +G+  NWRETMKILTG  EIKS SLLKFF+PL+ WLK  N+ L+  +GW
Sbjct:   12 IFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 610          

Query:  218 VFDSYYHMTDLESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +FDSY+++T+LE YP VC+EY++E CAK W  K+NEI+IRN NR+AN++++Y ++INK NLEL K+FQ I  K+G  ++ K+KKF WK F SP +R+    ++ ++R+++E++   L+ + + I YIYNN KPCF  CL  GE  II LFK EKDY+KL GYW AWRNVTG +I+ LF+++++LEN+G+RENG  D A++ L  DFE+++FK T ++LY  ILPLYKELH +VRYCL K+YPGKFDK+GPIPAHIFGNVW+Q+WTNIF I++ C +     N+ ++A+  L K+ V +MF +AEEFY SIG+FKMT+EFWERS++ +   ++++CHGSAHDF+NGVD+RI MCT+K++ DFTTIHHEMGHIEY+MAYS LPT +R SANSGFHEAIGDTIALAVKTPEHLHKIGL+  +P SK FDI+YLM +ALEKVAFLPFAL MDSYIW +YNG++P S++N++WWDL  +YQG+ PPV+R+E DFD G+KYHI+F V YIRYF+SF+IQFQFYESMC++SGYKGPLHRC+FYQS +AG KL+EML +GK  NWRETMK LTG  EIKS SLLKFF+PL+ WLK  N+ L+  +GW
Sbjct:   28 IFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQKWTNIFEIVKKCMKSNYQNNFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGKKNNWRETMKTLTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 626          

Query:  209 EPSVFDSYYHMTDLESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            +  +FDSY+++T+LE YP VC+EY++E CAK W  K+NEI+IRN NR+AN++++Y ++INK NLEL K+FQ I  K+G  ++ K+KKF WK F SP +R+    ++ ++R+++E++   L+ + + I YIYNN KPCF  CL  GE  II LFK EKDY+KL GYW AWRNVTG +I+ LF+++++LEN+G+RENG  D A++ L  DFE+++FK T ++LY  ILPLYKELH +VRYCL K+YPGKFDK+GPIPAHIFGNVW+QQWTNIF I++ C +     ++ ++A+  L K+ V +MF +AEEFY SIG+FKMT+EFWERS++ +   ++++CHGSAHDF+NGVD+RI MCT+K++ DFTTIHHEMGHIEY+MAYS LPT +R SANSGFHEAIGDTIALAVKTPEHLHKIGL+  +P SK FDI+YLM +ALEKVAFLPFAL MDSYIW +YNG++P S++N++WWDL  +YQG+ PPV+R+E DFD G+KYHI+F V YIRYF+SF+IQFQFYESMC++SGYKGPLHRC+FYQS +AG KL+EML +G+  NWRETMKILTG  EIKS SLLKFF+PL+ WLK  N+ L+  +GW
Sbjct:   29 QKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 630          

Query:  218 VFDSYYHMTDLESYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRXXXXXXXXXXXXXXXXXXXXXXXPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNMVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 2014
            VFDS+Y +T LE YP+ C    SE CA+ W  K+NEI IRN NR AN++++Y+T+I   NL L  +F+    K    L   +K F W+ F S ++R  F +IT S+++ +  +   +I I N I +IYN A+PC+  CL  GESGI+ LF TEK+Y+ L GYW  WR  TG +I+ L++ R  LE   ++ENG ++ A++ +  DF++++F  T +KL+  ++P+YK+LH YVRYCL ++YP +F+K+GPIPAHI G+VWAQ W NIFPII+ C +  +  +   E    LSKM V Q+F   E  Y  +GM++MT+EFWERS+ +KP D++V+CH S+ DFSNG DFR+KMC++K +  F+ IHHEMGHI+Y+MAY HLP ++R SANS F E IGDT+AL++KT   L KIGL+S +P +   +IDYLM  ALE V F+PFA+    ++  LYNGSVP S +N +WW L + YQG+ PP++RTE++FDPGSKYHI+FG+ YIR+FVS L++FQF+ES+C ++    PLH C  YQSK  G  L+E++  G+ + WRE +KI+    +I+S+SLL+FF PL +WL  TNK LNI +GW
Sbjct:   38 VFDSFYWLTPLEYYPDSC---LSETCAENWLVKVNEIMIRNENRIANVYYRYATNITSDNLMLLNQFRITKVKYENNLISIAKGFPWQQFYSKKMREMFEIITTSVKSVDPEVFKRIIKIKNRIEHIYNKARPCYKTCLSAGESGIVNLFNTEKNYDTLLGYWIVWRKETGVQIRDLYIDRFNLEIQAAKENGIQNIASFKMFEDFQEENFLETLMKLFDNVMPIYKQLHAYVRYCLAEYYPDRFNKTGPIPAHILGDVWAQNWINIFPIIKQCSRNNNPFHVFHEVNFKLSKMSVNQIFKTVESNYVGMGMYQMTNEFWERSLFTKPNDRIVDCHSSSEDFSNGFDFRVKMCSKKTVSYFSAIHHEMGHIQYFMAYQHLPILYRASANSAFQEIIGDTMALSMKTLSSLEKIGLLSNIPKTFDLEIDYLMLLALENVPFVPFAMINSVFVNSLYNGSVPTSRMNSYWWKLVHTYQGIKPPIERTEENFDPGSKYHIAFGIPYIRHFVSSLLKFQFFESLCEMNKGIEPLHFCTLYQSKNVGSLLIEIMKNGQRKPWREIIKIINRNEDIQSDSLLRFFAPLTQWLIKTNKMLNIHVGW 633