Granulin b

Overview


Name	Granulin b
Smed ID	SMED30034503
Length (bp)	757

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Granulin b (SMED30034503) t-SNE clustered cells

Violin plots show distribution of expression levels for Granulin b (SMED30034503) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Granulin b (SMED30034503) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Granulin b (SMED30034503) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034503

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30034503	h1SMcG0010631	Contig45753	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034503	h1SMcG0010631	Contig45753	newmark_ests	PMID:29674431 Fincher et al., 2018
nervous system	SMED30034503	h1SMcG0010631	dd_Smed_v4_67_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30034503	h1SMcG0010631	dd_Smed_v4_67_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30034503	h1SMcG0010631	dd_Smed_v4_67_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30034503	h1SMcG0010631	dd_Smed_v4_67_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30034503	h1SMcG0010631	dd_Smed_v4_67_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30034503	h1SMcG0010631	dd_Smed_v4_67_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30034503	h1SMcG0010631	dd_Smed_v6_67_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30034503	h1SMcG0010631	dd_Smed_v6_67_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
glial cell	SMED30034503	h1SMcG0010631	dd_Smed_v6_67_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 82.0333 bits (201), Expect = 2.244e-17
Identity = 61/184 (33.15%), Postives = 83/184 (45.11%), Query Frame = 2

Query:  143 FLMKCPSLFLCALFL--CIFVYDITTDGVTTFKQVDEDGCKNSNKI-CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
             L  CP   +C L    C+   + TTD +T          K   ++ C +  TCC  + G   CC +T AVCCED  HCCP G TCDT+   C  Q    + W    +K  A  ++P             +++     C +   C    TCC LT+G +GCCP    VCC D + CCP G  C+
Sbjct:   57 HLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC-EQGPHQVPWM---EKAPAHLSLPD-----------PQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCV 225

HSP 2 Score: 72.4034 bits (176), Expect = 5.354e-14
Identity = 50/143 (34.97%), Postives = 66/143 (46.15%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C ++   C +  TCC    GK  CC   NA CC D  HCCP+ T CD    +C+  SKE       +     +  +P +TV             ++  CPDG       TCC L +G +GCCP++  VCC D   CCP G  C
Sbjct:   22 CPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCL--SKE-------NATTDLLTKLPAHTVGDV-------KCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTC 142

HSP 3 Score: 58.5362 bits (140), Expect = 2.243e-9
Identity = 41/123 (33.33%), Postives = 56/123 (45.53%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPY 625
            + +  C   +TCC +  G   CCQ  +AVCCED  HCCP G TC+ K + C               +   + A P   + RSP       +G+K+V C +G  C    TCC      + CCPY
Sbjct:  259 DQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC---------------EKEVVSAQPATFLARSP------HVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPY 360

HSP 4 Score: 54.6842 bits (130), Expect = 4.374e-8
Identity = 41/136 (30.15%), Postives = 54/136 (39.71%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C    TCC    G+  CC    AVCC D  HCCP+G TC  +            +     + +  ++ +P      S  R+    IG    C     C    TCC    G + CC     VCC D++ CCP G  C
Sbjct:  186 CPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEG-----------QCQRGSEIVAGLEKMPARRASLSHPRD----IG----CDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 302

[Close]

BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 82.0333 bits (201), Expect = 3.265e-17
Identity = 61/184 (33.15%), Postives = 83/184 (45.11%), Query Frame = 2

Query:  143 FLMKCPSLFLCALFL--CIFVYDITTDGVTTFKQVDEDGCKNSNKI-CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
             L  CP   +C L    C+   + TTD +T          K   ++ C +  TCC  + G   CC +T AVCCED  HCCP G TCDT+   C  Q    + W    +K  A  ++P             +++     C +   C    TCC LT+G +GCCP    VCC D + CCP G  C+
Sbjct:  243 HLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC-EQGPHQVPWM---EKAPAHLSLPD-----------PQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCV 411

HSP 2 Score: 80.8777 bits (198), Expect = 7.856e-17
Identity = 52/143 (36.36%), Postives = 69/143 (48.25%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
            + +  C   +TCC +  G   CCQ  +AVCCED  HCCP G TC+ K + C               +   + A P   + RSP       +G+K+V C +G  C    TCC      + CCPY  GVCC D+R CCP G +C 
Sbjct:  445 DQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC---------------EKEVVSAQPATFLARSP------HVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCA 566

HSP 3 Score: 73.9442 bits (180), Expect = 1.666e-14
Identity = 60/198 (30.30%), Postives = 80/198 (40.40%), Query Frame = 2

Query:  200 YDITTDGVTTFKQVDEDG-----CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNG-------RKCIPGSCI*FELY*RLFLDQIGFMKCD 757
            +  + DG + F++   +      C +S   C +  TCC+   G   CC    A CCED  HCCP G  CD  + RCI         T +     A K   + T     L         ++ CPDG       TCC L +G YGCCP     CC D   CCP          KC+       +L  +L    +G +KCD
Sbjct:  103 FHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCI---------TPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGS------TCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCD 285

HSP 4 Score: 73.1738 bits (178), Expect = 4.026e-14
Identity = 50/143 (34.97%), Postives = 66/143 (46.15%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C ++   C +  TCC    GK  CC   NA CC D  HCCP+ T CD    +C+  SKE       +     +  +P +TV             ++  CPDG       TCC L +G +GCCP++  VCC D   CCP G  C
Sbjct:  208 CPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCL--SKE-------NATTDLLTKLPAHTVGDV-------KCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTC 328

HSP 5 Score: 59.3066 bits (142), Expect = 1.796e-9
Identity = 40/140 (28.57%), Postives = 57/140 (40.71%), Query Frame = 2

Query:  266 NKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +  C    +C  T  G   CC +  AV C D  HCCP G  C    + C  +S         ++ + AI+                        CPD   +C  + TCC++ +G +GCCP     CC D+  CCP+G  C
Sbjct:   64 DAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRS--------GNNSVGAIQ------------------------CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171

[Close]

BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 80.8777 bits (198), Expect = 6.527e-17
Identity = 52/143 (36.36%), Postives = 69/143 (48.25%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
            + +  C   +TCC +  G   CCQ  +AVCCED  HCCP G TC+ K + C               +   + A P   + RSP       +G+K+V C +G  C    TCC      + CCPY  GVCC D+R CCP G +C 
Sbjct:  288 DQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC---------------EKEVVSAQPATFLARSP------HVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCA 409

HSP 2 Score: 80.1073 bits (196), Expect = 1.376e-16
Identity = 55/167 (32.93%), Postives = 76/167 (45.51%), Query Frame = 2

Query:  200 YDITTDGVTTFKQ-----VDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
            +  + DG + F++     V    C +S   C +  TCC+   G   CC    AVCCED  HCCP G TCDT+   C  Q    + W    +K  A  ++P             +++     C +   C    TCC LT+G +GCCP    VCC D + CCP G  C+
Sbjct:  103 FHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQAVCCEDHIHCCPAGFTCDTQKGTC-EQGPHQVPWM---EKAPAHLSLPD-----------PQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCV 254

HSP 3 Score: 60.077 bits (144), Expect = 6.916e-10
Identity = 41/137 (29.93%), Postives = 55/137 (40.15%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C    +C  T  G   CC +  AV C D  HCCP G  C    + C  +S         ++ + AI+                        CPD   +C  + TCC++ +G +GCCP    VCC D   CCP G  C
Sbjct:   67 CSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRS--------GNNSVGAIQ------------------------CPDSQFECPDFSTCCVMVDGSWGCCPMPQAVCCEDHIHCCPAGFTC 171

[Close]

BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 78.5666 bits (192), Expect = 3.992e-16
Identity = 60/184 (32.61%), Postives = 81/184 (44.02%), Query Frame = 2

Query:  143 FLMKCPSLFLCALFL--CIFVYDITTDGVTTFKQVDEDGCKNSNKI-CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
             L  CP   +C L    C+   + TTD +T          K   ++ C +  TCC  + G   CC +T AVCCED  HCCP G TCDT+   C  Q    + W    +K  A  ++P             +++     C +   C    TCC      + CCPY  GVCC D+R CCP G +C 
Sbjct:  243 HLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC-EQGPHQVPWM---EKAPAHLSLPD-----------PQALKRDVPCDNVSSCPSSDTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCA 411

HSP 2 Score: 73.9442 bits (180), Expect = 1.430e-14
Identity = 59/200 (29.50%), Postives = 83/200 (41.50%), Query Frame = 2

Query:  200 YDITTDGVTTFKQVDEDG-----CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS-KEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNG-------RKCIPGSCI*FELY*RLFLDQIGFMKCD 757
            +  + DG + F++   +      C +S   C +  TCC+   G   CC    A CCED  HCCP G  CD  + RCI  +   P+            K +P     R+       ++    +CPD   +C    TCC L +G YGCCP     CC D   CCP          KC+       +L  +L    +G +KCD
Sbjct:  103 FHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPL-----------AKKLPAQRTNRA------VALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCD 285

HSP 3 Score: 73.1738 bits (178), Expect = 3.018e-14
Identity = 50/143 (34.97%), Postives = 66/143 (46.15%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C ++   C +  TCC    GK  CC   NA CC D  HCCP+ T CD    +C+  SKE       +     +  +P +TV             ++  CPDG       TCC L +G +GCCP++  VCC D   CCP G  C
Sbjct:  208 CPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCL--SKE-------NATTDLLTKLPAHTVGDV-------KCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTC 328

HSP 4 Score: 59.6918 bits (143), Expect = 1.210e-9
Identity = 40/137 (29.20%), Postives = 56/137 (40.88%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C    +C  T  G   CC +  AV C D  HCCP G  C    + C  +S         ++ + AI+                        CPD   +C  + TCC++ +G +GCCP     CC D+  CCP+G  C
Sbjct:   67 CSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRS--------GNNSVGAIQ------------------------CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171

[Close]

BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 58.5362 bits (140), Expect = 4.996e-10
Identity = 39/119 (32.77%), Postives = 51/119 (42.86%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS-KEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPY 625
            C    +C  T  G   CC +  A CCED  HCCP G  CD  + RCI  +   P+            K +P     R+       ++    +CPD   +C    TCC L +G YGCCP 
Sbjct:   67 CSAGHSCIFTVSGTSSCCPFPEASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLA-----------KKLPAQRTNRA------VALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPM 168

[Close]

BLAST of Granulin b vs. Ensembl Celegans
Match: pgrn-1 (ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:Q7JKP2])

HSP 1 Score: 94.3597 bits (233), Expect = 2.187e-22
Identity = 72/186 (38.71%), Postives = 87/186 (46.77%), Query Frame = 2

Query:  134 SEVFLMKCPSLFLCALFLCIFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKE--PMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPD-GGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            S +F +K   L L  LFL +F+  +T        Q D +        C + +TCC        CC   NAVCC+D SHCCP GTTCD +  RCI   ++  PM+           K   + TVER+   E         VCPD   KC    TCCLL  G YGCCP    VCC D   CCPNG  C
Sbjct:   71 SFIFSIKIMRLIL--LFLAVFLCRVTA------HQCDAE------TECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKK----------KKPARKTVERNQFNEV--------VCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTC 224

[Close]

BLAST of Granulin b vs. Ensembl Celegans
Match: pgrn-1 (ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:Q7JKP2])

HSP 1 Score: 93.9745 bits (232), Expect = 3.069e-22
Identity = 72/186 (38.71%), Postives = 87/186 (46.77%), Query Frame = 2

Query:  134 SEVFLMKCPSLFLCALFLCIFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKE--PMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPD-GGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            S +F +K   L L  LFL +F+  +T        Q D      +   C + +TCC        CC   NAVCC+D SHCCP GTTCD +  RCI   ++  PM+           K   + TVER+   E         VCPD   KC    TCCLL  G YGCCP    VCC D   CCPNG  C
Sbjct:   71 SFIFSIKIMRLIL--LFLAVFLCRVTA------HQCD------AETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKK----------KKPARKTVERNQFNEV--------VCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTC 224

HSP 2 Score: 56.9954 bits (136), Expect = 2.655e-9
Identity = 52/174 (29.89%), Postives = 68/174 (39.08%), Query Frame = 2

Query:  236 QVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWY------------------ESIGLKNVCPDGGKCTGYLTCCLLT--NGH--YGCCPYSFGVCCPDKRTCCPNGRKCIPG 691
            Q +E  C +    C +  TCC+ + G   CC   NAVCC DM HCCP G TC        H       + +    I  ++     ++ R P  E+                   ES      C  G  C    TCC +   NG     CCP S  +CC  + TCCP G  C+ G
Sbjct:  173 QFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTC--------HGQFCSQNFAM----IPHLRKFASTSIHRKPAVEFLSEEEEDDDDEESTSSEDPESDVDPIACGVGKTCPAKTTCCNVRGKNGEPKTMCCPLSNAICC--ENTCCPAGYHCVDG 332

[Close]

BLAST of Granulin b vs. Ensembl Zebrafish
Match: grnb (granulin b [Source:ZFIN;Acc:ZDB-GENE-030131-7393])

HSP 1 Score: 84.7297 bits (208), Expect = 2.525e-18
Identity = 54/145 (37.24%), Postives = 71/145 (48.97%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +    C +  TCC    G   CC   NAVCC+D  HCCP+GTTCD  +  C+  +        S   +    A  +  +E++ +    E   ++ V CPD   KC    TCCLL  G YGCCP    VCC D++ CCP G  C
Sbjct:   95 CPDGESECPDDTTCCQMPDGGWGCCPMKNAVCCDDRKHCCPQGTTCDLVHSMCVSTTYG------SSPFLRKFDARRRKPLEKNAVDLPAEVNNIREVICPDKISKCPEDTTCCLLETGSYGCCPMPKAVCCSDQKHCCPEGTTC 233

HSP 2 Score: 78.9518 bits (193), Expect = 2.802e-16
Identity = 55/162 (33.95%), Postives = 66/162 (40.74%), Query Frame = 2

Query:  218 GVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCP-------DGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             VT  K  +E    N    C    TCC T  G   CC    AVCCED  HCCPEGT C+     C             DD      ++P           W E +  K + P       +   C G  TCC L++G +GCCP    VCC D   CCP+G  C
Sbjct:  255 AVTVLKPKEEVVPCNETVACSSGTTCCKTPEGSWACCPLPKAVCCEDHIHCCPEGTLCNVAASSC-------------DDPAGLSVSVP-----------WMEKVSTKPIAPPPNKKCDESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVC 392

HSP 3 Score: 73.559 bits (179), Expect = 1.627e-14
Identity = 48/141 (34.04%), Postives = 67/141 (47.52%), Query Frame = 2

Query:  272 ICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLK---NVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +C +  TCC+T  G   CC   +A CC D  HCC +GT CD ++ +C+             +K H +              +W E +  K    VCPDG  +C    TCC + +G +GCCP    VCC D++ CCP G  C
Sbjct:   27 MCEDGNTCCLTPSGGYGCCPLPHAECCSDHLHCCYQGTLCDLEHSKCV-------------NKTHVL--------------DWVEKVEAKLQAVVCPDGESECPDDTTCCQMPDGGWGCCPMKNAVCCDDRKHCCPQGTTC 140

HSP 4 Score: 72.4034 bits (176), Expect = 4.116e-14
Identity = 47/141 (33.33%), Postives = 61/141 (43.26%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            + +  C  + TCC    G   CC    AVCCED  HCCP G+ C+   + C   S   +  +V       +K IP  +V              K  C +   C    TCC LT+G + CCP    VCC D+  CCP G  C
Sbjct:  349 DESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDSGLRISVP-----MVKKIPAVSVPSQ-----------KQNCDETSSCPTGTTCCKLTSGSWACCPMPQAVCCADQEHCCPQGYTC 473

HSP 5 Score: 70.8626 bits (172), Expect = 1.352e-13
Identity = 51/158 (32.28%), Postives = 64/158 (40.51%), Query Frame = 2

Query:  209 TTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
              D       + E  C +    C E  TCC+ + G   CC    AVCC D  HCCPEGTTCD  +  C+           ++        IP  TV    L+   E +     C +   C+   TCC    G + CCP    VCC D   CCP G  C
Sbjct:  173 AVDLPAEVNNIREVICPDKISKCPEDTTCCLLETGSYGCCPMPKAVCCSDQKHCCPEGTTCDLIHSTCLS----------ANGVSEMATKIPAVTV----LKPKEEVVP----CNETVACSSGTTCCKTPEGSWACCPLPKAVCCEDHIHCCPEGTLC 312

HSP 6 Score: 70.8626 bits (172), Expect = 1.661e-13
Identity = 51/155 (32.90%), Postives = 70/155 (45.16%), Query Frame = 2

Query:  233 KQVDEDGCKNSNKICGEQKTCC-MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYES---IGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            ++V++    ++   C    TCC + +IGK  CC    AVCC+D  HCCP G TC+ +   C                   +  IP +T  +   R W  S   +G ++V C     C    TCC+L  G +GCCP    VCC D   CCP G  C
Sbjct:  501 QRVEDRHMCDAQTSCPRDDTCCFINRIGKWGCCPLPKAVCCKDGDHCCPSGYTCNEEKTSC----------------TKGLHQIPWFT--KKTARVWKSSDELLGHEDVKCDSSTSCPSGSTCCILPTGQWGCCPLVKAVCCEDHEHCCPQGYIC 637

HSP 7 Score: 68.1662 bits (165), Expect = 1.251e-12
Identity = 43/142 (30.28%), Postives = 55/142 (38.73%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTN-GHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +    C    TCC    G   CC    AVCC D  HCCP+G TCD     C+      M W                   + P     + +  +++C     C    TCC +   G +GCCP    VCC D   CCP+G  C
Sbjct:  430 DETSSCPTGTTCCKLTSGSWACCPMPQAVCCADQEHCCPQGYTCDLAQSSCVRSGLPSMAW-----------------FRKEPALRETQRVEDRHMCDAQTSCPRDDTCCFINRIGKWGCCPLPKAVCCKDGDHCCPSGYTC 554

HSP 8 Score: 66.2402 bits (160), Expect = 5.508e-12
Identity = 44/143 (30.77%), Postives = 62/143 (43.36%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIP 688
            +S+  C    TCC+   G+  CC    AVCCED  HCCP+G  C  +   C              +K  A  ++    V+   ++           C    +C    +CC L +  + CCPY+  VCC D + CCP G KC P
Sbjct:  594 DSSTSCPSGSTCCILPTGQWGCCPLVKAVCCEDHEHCCPQGYICKLELGTC--------------EKASADVSVSLTAVQMPEIQ-----------CDTFTRCAHTQSCCRLADSTWACCPYTQAVCCKDMKHCCPMGYKCDP 711

[Close]

BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 76.6406 bits (187), Expect = 4.492e-17
Identity = 53/143 (37.06%), Postives = 66/143 (46.15%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKN--VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            N    C +  TCC TK G   CC    AVCCED  HCCP G  CD     C   S   + W    +K+  ++ I K  V  + +      I   +   CPDG       TCC   +G +GCCP    VCC D   CCP+G+KC
Sbjct:    8 NDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGS-VPWV---EKV-PVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGS------TCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKC 139

HSP 2 Score: 47.7506 bits (112), Expect = 1.341e-6
Identity = 27/65 (41.54%), Postives = 30/65 (46.15%), Query Frame = 2

Query:  218 GVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRC 412
             VTT   V  D   N    C +  TCC  K G+  CC    AVCCED  HCCP G  C+     C
Sbjct:   82 AVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSC 146

[Close]

BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 75.8702 bits (185), Expect = 1.871e-16
Identity = 51/155 (32.90%), Postives = 64/155 (41.29%), Query Frame = 2

Query:  218 GVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             VT       D   N    C +  TCC TK G   CC    AVCCED  HCCP G  CD     C   S   + W         ++ +P   + +  +      +     C D   C    TCC   +G +GCCP    VCC D   CCP+G+KC
Sbjct:   16 AVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSC-EDSSGSVPW---------VEKVPVRPIRKQKVAN--TKVSSDVACNDTVACPDGSTCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKC 158

[Close]

BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 77.411 bits (189), Expect = 8.877e-16
Identity = 51/145 (35.17%), Postives = 69/145 (47.59%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPG 691
            +    C    TCC+    +  CC +  AVCC D  HCCPEG  CD + + C+  ++  +E             I + T  RS   +   S+ +K+V C  G  C    TCCL +   +GCCP    VCC D + CCP G KC PG
Sbjct:  890 DEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVE-------------ITQLTHIRS--NKPQPSVVVKDVQCGGGFSCHDGETCCLTSQTTWGCCPSPKAVCCDDMQHCCPAGYKCGPG 1019

HSP 2 Score: 75.8702 bits (185), Expect = 3.602e-15
Identity = 55/157 (35.03%), Postives = 69/157 (43.95%), Query Frame = 2

Query:  218 GVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKN--VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             VTT   V  D   N    C +  TCC  K G+  CC    AVCCED  HCCP G  C+     C   S   + W    DK+  ++ I K  V  +        +   +   CPDG       TCC   +G + CCP    VCC D   CCP+G+KC
Sbjct:  539 AVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGS-VPWM---DKV-PVRPIKKQKVAVTQASSASSDVPCNDTAACPDGS------TCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKC 684

HSP 3 Score: 75.0998 bits (183), Expect = 5.814e-15
Identity = 53/151 (35.10%), Postives = 65/151 (43.05%), Query Frame = 2

Query:  230 FKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             + V  D   N    C +  TCC TK G   CC    AVCCED  HCCP G  CD     C   S   + W    +K+  ++ I K  V  + +     S+     C D   C    TCC    G + CCP    VCC D   CCP G+KC
Sbjct:  282 HQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGS-VSWV---EKV-PVRPIRKQKVAVTQV----SSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKC 423

HSP 4 Score: 74.7146 bits (182), Expect = 8.705e-15
Identity = 46/141 (32.62%), Postives = 68/141 (48.23%), Query Frame = 2

Query:  263 SNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSK-EPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +N++C   ++CC    G   CC + +  CCED  HCCPEG  C  K+  C + +  +P+    +D  +     +PK       +      I     CPDG  C    + CLL +  YGCCP + G+ C D + CCPN  +C
Sbjct:   21 NNEVCEAGQSCCQDPTGGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPL----ADRTLAKKPDLPKSFRMIFSMPASESDI----TCPDGSSCPAEFS-CLLMSTSYGCCPVAQGLACSDGKHCCPNDHEC 152

HSP 5 Score: 73.559 bits (179), Expect = 1.694e-14
Identity = 47/141 (33.33%), Postives = 64/141 (45.39%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            N+   C E  TCC    G+  CC ++ AVCC D  HCCP    C+  +  CI                  I    K   E +P  +    +G+   C +   C+   TCCLL+    GCCP+   VCCPD++ CCP G +C
Sbjct:  809 NATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDV-------------VIPWYNKIAAESTPAPKL--DLGVVK-CDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRC 933

HSP 6 Score: 72.7886 bits (177), Expect = 3.487e-14
Identity = 52/156 (33.33%), Postives = 66/156 (42.31%), Query Frame = 2

Query:  218 GVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             VT    V  D   N    C +  TCC TK G   CC    AVCCED  HCCP+G  C+    +C             +D +   + + K T  +S            +V C D   C    TCC   +G + CCP    VCC D   CCP+G+KC
Sbjct:  366 AVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKC-------------EDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKC 508

HSP 7 Score: 72.4034 bits (176), Expect = 4.795e-14
Identity = 53/165 (32.12%), Postives = 68/165 (41.21%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKE--PM----------EWTVSDDK---IHAIKAIPKYTV-------ERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C N    C    TCC    G+  CC    AVCC+D  HCCPE T CD K  +C+  + +  PM          EW     K        A P  T        + + L   ++ +     C D   C    TCC   +G + CCP    VCC D   CCP+G+KC
Sbjct:  171 CGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKC 335

HSP 8 Score: 68.1662 bits (165), Expect = 1.467e-12
Identity = 53/153 (34.64%), Postives = 60/153 (39.22%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            T    V  D   N    C +  TCC  K G   CC    AVCCED  HCCP G  C+     C             DD   ++  + K  V    LR      G K  C     C    TCC    G +GCCP+S  VCC D   CCP   KC
Sbjct:  717 TKVSPVSSDVACNDTVACPDGSTCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSC-------------DDPSGSVPWVEKVPVH---LRAGQRPSG-KVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKC 852

[Close]

BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 77.411 bits (189), Expect = 9.283e-16
Identity = 51/145 (35.17%), Postives = 69/145 (47.59%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPG 691
            +    C    TCC+    +  CC +  AVCC D  HCCPEG  CD + + C+  ++  +E             I + T  RS   +   S+ +K+V C  G  C    TCCL +   +GCCP    VCC D + CCP G KC PG
Sbjct:  714 DEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVE-------------ITQLTHIRS--NKPQPSVVVKDVQCGGGFSCHDGETCCLTSQTTWGCCPSPKAVCCDDMQHCCPAGYKCGPG 843

HSP 2 Score: 75.0998 bits (183), Expect = 5.641e-15
Identity = 53/148 (35.81%), Postives = 64/148 (43.24%), Query Frame = 2

Query:  239 VDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V  D   N    C +  TCC TK G   CC    AVCCED  HCCP G  CD     C   S   + W    +K+  ++ I K  V  + +     S+     C D   C    TCC    G + CCP    VCC D   CCP G+KC
Sbjct:  285 VSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGS-VSWV---EKV-PVRPIRKQKVAVTQV----SSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKC 423

HSP 3 Score: 74.7146 bits (182), Expect = 7.067e-15
Identity = 46/141 (32.62%), Postives = 68/141 (48.23%), Query Frame = 2

Query:  263 SNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSK-EPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +N++C   ++CC    G   CC + +  CCED  HCCPEG  C  K+  C + +  +P+    +D  +     +PK       +      I     CPDG  C    + CLL +  YGCCP + G+ C D + CCPN  +C
Sbjct:   21 NNEVCEAGQSCCQDPTGGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPL----ADRTLAKKPDLPKSFRMIFSMPASESDI----TCPDGSSCPAEFS-CLLMSTSYGCCPVAQGLACSDGKHCCPNDHEC 152

HSP 4 Score: 73.559 bits (179), Expect = 1.644e-14
Identity = 47/141 (33.33%), Postives = 64/141 (45.39%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            N+   C E  TCC    G+  CC ++ AVCC D  HCCP    C+  +  CI                  I    K   E +P  +    +G+   C +   C+   TCCLL+    GCCP+   VCCPD++ CCP G +C
Sbjct:  633 NATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDV-------------VIPWYNKIAAESTPAPKL--DLGVVK-CDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRC 757

HSP 5 Score: 72.7886 bits (177), Expect = 2.969e-14
Identity = 55/163 (33.74%), Postives = 69/163 (42.33%), Query Frame = 2

Query:  218 GVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC--IPGSC 697
             VT    V  D   N    C +  TCC TK G   CC    AVCCED  HCCP+G  C+    +C             +D +   + + K T  +S            +V C D   C    TCC   +G + CCP    VCC D   CCP+G+KC    GSC
Sbjct:  366 AVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKC-------------EDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSC 515

HSP 6 Score: 72.4034 bits (176), Expect = 4.442e-14
Identity = 56/172 (32.56%), Postives = 71/172 (41.28%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKE--PM----------EWTVSDDK---IHAIKAIPKYTV-------ERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC--IPGSC 697
            C N    C    TCC    G+  CC    AVCC+D  HCCPE T CD K  +C+  + +  PM          EW     K        A P  T        + + L   ++ +     C D   C    TCC   +G + CCP    VCC D   CCP+G+KC    GSC
Sbjct:  171 CGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSC 342

HSP 7 Score: 72.4034 bits (176), Expect = 5.112e-14
Identity = 55/155 (35.48%), Postives = 63/155 (40.65%), Query Frame = 2

Query:  218 GVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             VTT   V  D   N    C +  TCC  K G+  CC    AVCCED  HCCP G  C+     C             DD   ++  + K  V    LR      G K  C     C    TCC    G +GCCP+S  VCC D   CCP   KC
Sbjct:  539 AVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSC-------------DDPSGSVPWVEKVPVH---LRAGQRPSG-KVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKC 676

[Close]

BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148])

HSP 1 Score: 75.485 bits (184), Expect = 5.318e-15
Identity = 52/144 (36.11%), Postives = 70/144 (48.61%), Query Frame = 2

Query:  272 ICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKE-PMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
             C +  TCC        CC   +AVCC D  HCCP GTTCD  +K+C+ Q+ E P+        +  + AI + +  + P             CPD        TCC L++  +GCCPY+  VCC D   CCP+G  C  GSC+
Sbjct:  215 FCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPL--------LPQMPAIREESANQVPCDA-------TTSCPDKN------TCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCSGGSCV 337

HSP 2 Score: 72.0182 bits (175), Expect = 8.784e-14
Identity = 64/213 (30.05%), Postives = 82/213 (38.50%), Query Frame = 2

Query:  155 CPSLFLCALFLCIFVYDITTDGVTTFKQVDEDGCK------NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI*FELY*RLF------LDQIGFMKCD 757
            CPS F C+   C+    +    +   ++    G K      +    C E++TCC    GK  CC    AVCC D  HCCPEG TC               E +  +  I      P  T E   +            C D   C    TCC L +G +GCCP +  VCC D   CCP G  C  G C   E    LF        +  ++KCD
Sbjct:  325 CPSGFTCSGGSCV----LAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQG------------ECSKMEHSIPWFTKTPALTHEARDVE-----------CDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETKYVKCD 510

HSP 3 Score: 65.855 bits (159), Expect = 9.807e-12
Identity = 51/153 (33.33%), Postives = 62/153 (40.52%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV---CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI*FE 709
            ++   C ++ TCC     K  CC Y  AVCC+D  HCCP G TC      C+                H+I  + K   +           GLK     C D   C    TCC L +G +GCCP    VCC D   CCP G  C  G C   E
Sbjct:  288 DATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTC--SGGSCVLAE-------------HSIPWMRKTLAQ-----------GLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQGECSKME 414

HSP 4 Score: 65.0846 bits (157), Expect = 2.064e-11
Identity = 45/146 (30.82%), Postives = 59/146 (40.41%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSC 697
            +    C + +TCC    G   CC    AVCC+D  HCCP G TC     +C+          + +  I      P    +   ++           C D   C    TCC L +G +GCCP +  VCC D   CCP G  C  G C
Sbjct:  510 DDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGSQCM----------IGEHSIPWFSKTPALKQKAKDVQ-----------CDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQC 632

HSP 5 Score: 63.1586 bits (152), Expect = 7.937e-11
Identity = 48/149 (32.21%), Postives = 61/149 (40.94%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCM-TKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKN-----VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +    C    TCCM + +    CC    AVCC+D  HCCP  + CD +  RCI           + D I  +  +P          E  + +GL +      C DG  C    TCC   +  YGCC     VCC D   CCP G  C
Sbjct:  121 CPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCIS----------NQDHIPWMSKLPARVKS-----EGLKLVGLGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTC 254

[Close]

BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148])

HSP 1 Score: 75.485 bits (184), Expect = 6.874e-15
Identity = 52/144 (36.11%), Postives = 70/144 (48.61%), Query Frame = 2

Query:  272 ICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKE-PMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
             C +  TCC        CC   +AVCC D  HCCP GTTCD  +K+C+ Q+ E P+        +  + AI + +  + P             CPD        TCC L++  +GCCPY+  VCC D   CCP+G  C  GSC+
Sbjct:  215 FCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPL--------LPQMPAIREESANQVPCDA-------TTSCPDKN------TCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCSGGSCV 337

HSP 2 Score: 71.633 bits (174), Expect = 1.234e-13
Identity = 61/197 (30.96%), Postives = 80/197 (40.61%), Query Frame = 2

Query:  155 CPSLFLCALFLCIFVYDITTDGVTTFKQVDEDGCK------NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI*FELY*RLF 727
            CPS F C+   C+    +    +   ++    G K      +    C E++TCC    GK  CC    AVCC D  HCCPEG TC       +  S   + W     K   +  +    +   P+     S+     C D   C    TCC L +G +GCCP +  VCC D   CCP G  C  G C   E    LF
Sbjct:  325 CPSGFTCSGGSCV----LAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQGECSKMEHS---IPWFT---KTPMVFFLSLSLLSILPVV----SVARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLF 507

HSP 3 Score: 69.707 bits (169), Expect = 5.410e-13
Identity = 51/159 (32.08%), Postives = 70/159 (44.03%), Query Frame = 2

Query:  227 TFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC-IPGSCI 700
              KQ  +D   +    C + +TCC    G   CC    AVCC+D  HCCP G TC         + +  + W     K  A+K   K  +  +P+  +  +I     C D   C    TCC + +G +GCCP    VCC D   CCP G  C   G+C+
Sbjct:  615 ALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQ---CQKGEHSIPWY---SKTPALKQEGKCNLANTPVNVFAGNI---VKCDDSFACKDGYTCCRMVSGVWGCCPIEKAVCCSDHWHCCPQGFTCDARGTCV 764

HSP 4 Score: 65.855 bits (159), Expect = 1.131e-11
Identity = 51/153 (33.33%), Postives = 62/153 (40.52%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV---CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI*FE 709
            ++   C ++ TCC     K  CC Y  AVCC+D  HCCP G TC      C+                H+I  + K   +           GLK     C D   C    TCC L +G +GCCP    VCC D   CCP G  C  G C   E
Sbjct:  288 DATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTC--SGGSCVLAE-------------HSIPWMRKTLAQ-----------GLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQGECSKME 414

HSP 5 Score: 65.4698 bits (158), Expect = 1.277e-11
Identity = 52/180 (28.89%), Postives = 70/180 (38.89%), Query Frame = 2

Query:  158 PSLFLCALFLCIFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSC 697
            P   L + F+C F        V  + + D+         C + +TCC    G   CC    AVCC+D  HCCP G TC     +C+          + +  I      P    +   ++           C D   C    TCC L +G +GCCP +  VCC D   CCP G  C  G C
Sbjct:  531 PLCLLFSPFICPF-------SVAKYVKCDD------THSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGSQCM----------IGEHSIPWFSKTPALKQKAKDVQ-----------CDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQC 674

HSP 6 Score: 63.1586 bits (152), Expect = 9.857e-11
Identity = 45/144 (31.25%), Postives = 56/144 (38.89%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCM-TKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +    C    TCCM + +    CC    AVCC+D  HCCP  + CD +  RCI           + D I  +  +P                  +  C DG  C    TCC   +  YGCC     VCC D   CCP G  C
Sbjct:  121 CPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCIS----------NQDHIPWMSKLPARVKSEGLKLVGLGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTC 254

HSP 7 Score: 60.8474 bits (146), Expect = 4.381e-10
Identity = 52/170 (30.59%), Postives = 65/170 (38.24%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSD---DKIHAI------------------------KAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
            + +  C +  TCC    G   CC    AVCC D  HCCP+G TCD +    + Q   P    V     D  H+I                            K  +E SP     + + L  V C     C    TCC    G + CC Y+ GVCCPD   CCP G  C+
Sbjct:  714 DDSFACKDGYTCCRMVSGVWGCCPIEKAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCPVEEKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRGLGGVWNCCVYTQGVCCPDMVHCCPYGYVCL 883

HSP 8 Score: 60.8474 bits (146), Expect = 5.370e-10
Identity = 47/148 (31.76%), Postives = 59/148 (39.86%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYE------SIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
            C + +TCC    G   CC    AVCC+D  HCCP G TC     +    S      T +  +  A            PL   +       S+     C D   C    TCC L +G +GCCP +  VCC D   CCP G  C    C+
Sbjct:  454 CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETACARRCGDDEYPFPLCLLFSPFICPFSVAKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGSQCM 601

[Close]

BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148])

HSP 1 Score: 68.5514 bits (166), Expect = 1.257e-12
Identity = 50/147 (34.01%), Postives = 64/147 (43.54%), Query Frame = 2

Query:  272 ICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKE-PMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI*FE 709
             C +  TCC        CC   +AVCC D  HCCP GTTCD  +K+C+ Q+ E P+        +  + AI + +  + P                    T   TCC L +G +GCCP    VCC D   CCP G  C  G C   E
Sbjct:  208 FCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPL--------LPQMPAIREESANQVPCD----------------ATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQGECSKME 330

HSP 2 Score: 66.2402 bits (160), Expect = 6.799e-12
Identity = 54/165 (32.73%), Postives = 66/165 (40.00%), Query Frame = 2

Query:  281 EQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI*FELY*RLF------LDQIGFMKCD 757
            +++TCC    GK  CC    AVCC D  HCCPEG TC               E +  +  I      P  T E   +            C D   C    TCC L +G +GCCP +  VCC D   CCP G  C  G C   E    LF        +  ++KCD
Sbjct:  285 KKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQG------------ECSKMEHSIPWFTKTPALTHEARDVE-----------CDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETKYVKCD 426

HSP 3 Score: 62.7734 bits (151), Expect = 9.536e-11
Identity = 45/148 (30.41%), Postives = 61/148 (41.22%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC-IPGSCI 700
            +    C + +TCC    G   CC    AVCC+D  HCCP G TC     +C+          + +  I      P    +   ++           C D   C    TCC L +G +GCCP +  VCC D   CCP G  C   G+C+
Sbjct:  426 DDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGSQCM----------IGEHSIPWFSKTPALKQKAKDVQ-----------CDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCV 550

HSP 4 Score: 62.7734 bits (151), Expect = 9.805e-11
Identity = 47/145 (32.41%), Postives = 61/145 (42.07%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCM-TKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +    C    TCCM + +    CC    AVCC+D  HCCP  + CD +  RCI  +++ + W                 + + P R   E    + V C DG  C    TCC   +  YGCC     VCC D   CCP G  C
Sbjct:  121 CPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCI-SNQDHIPW-----------------MSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTC 247

HSP 5 Score: 62.7734 bits (151), Expect = 1.137e-10
Identity = 50/142 (35.21%), Postives = 61/142 (42.96%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
            C + +TCC    G   CC    AVCC+D  HCCP G TC     +C  Q  E           H+I    K    R       E+  +K  C D   C    TCC L +G +GCCP +  VCC D   CCP G  C    C+
Sbjct:  357 CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQC--QKGE-----------HSIPLFSKTPALRQ------ETKYVK--CDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGSQCM 475

HSP 6 Score: 49.6766 bits (117), Expect = 2.358e-6
Identity = 37/132 (28.03%), Postives = 50/132 (37.88%), Query Frame = 2

Query:  227 TFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCP 622
              KQ  +D   +    C + +TCC    G   CC    AVCC D  HCCP+G TCD +    + Q   P            +  +P    +           G  ++C D   C    TCC    G + CCP
Sbjct:  489 ALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPW-----------LTKVPALPFD-----------GTHSICDDTHTCPSGTTCCPGEGGGWRCCP 598

[Close]

BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148])

HSP 1 Score: 68.5514 bits (166), Expect = 1.430e-12
Identity = 49/146 (33.56%), Postives = 62/146 (42.47%), Query Frame = 2

Query:  272 ICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI*FE 709
             C +  TCC        CC   +AVCC D  HCCP GTTCD  +K+C+ Q+ E          +  + AI + +  + P                    T   TCC L +G +GCCP    VCC D   CCP G  C  G C   E
Sbjct:  228 FCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGE-------GPLLPQMPAIREESANQVPCD----------------ATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQGECSKME 350

HSP 2 Score: 66.2402 bits (160), Expect = 8.175e-12
Identity = 54/165 (32.73%), Postives = 66/165 (40.00%), Query Frame = 2

Query:  281 EQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI*FELY*RLF------LDQIGFMKCD 757
            +++TCC    GK  CC    AVCC D  HCCPEG TC               E +  +  I      P  T E   +            C D   C    TCC L +G +GCCP +  VCC D   CCP G  C  G C   E    LF        +  ++KCD
Sbjct:  305 KKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQG------------ECSKMEHSIPWFTKTPALTHEARDVE-----------CDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETKYVKCD 446

HSP 3 Score: 62.7734 bits (151), Expect = 1.084e-10
Identity = 45/148 (30.41%), Postives = 61/148 (41.22%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC-IPGSCI 700
            +    C + +TCC    G   CC    AVCC+D  HCCP G TC     +C+          + +  I      P    +   ++           C D   C    TCC L +G +GCCP +  VCC D   CCP G  C   G+C+
Sbjct:  446 DDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGSQCM----------IGEHSIPWFSKTPALKQKAKDVQ-----------CDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCV 570

HSP 4 Score: 62.7734 bits (151), Expect = 1.125e-10
Identity = 47/145 (32.41%), Postives = 61/145 (42.07%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCM-TKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +    C    TCCM + +    CC    AVCC+D  HCCP  + CD +  RCI  +++ + W                 + + P R   E    + V C DG  C    TCC   +  YGCC     VCC D   CCP G  C
Sbjct:  141 CPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCI-SNQDHIPW-----------------MSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTC 267

HSP 5 Score: 62.3882 bits (150), Expect = 1.379e-10
Identity = 50/142 (35.21%), Postives = 61/142 (42.96%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
            C + +TCC    G   CC    AVCC+D  HCCP G TC     +C  Q  E           H+I    K    R       E+  +K  C D   C    TCC L +G +GCCP +  VCC D   CCP G  C    C+
Sbjct:  377 CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQC--QKGE-----------HSIPLFSKTPALRQ------ETKYVK--CDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGSQCM 495

HSP 6 Score: 49.6766 bits (117), Expect = 2.671e-6
Identity = 37/132 (28.03%), Postives = 50/132 (37.88%), Query Frame = 2

Query:  227 TFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCP 622
              KQ  +D   +    C + +TCC    G   CC    AVCC D  HCCP+G TCD +    + Q   P            +  +P    +           G  ++C D   C    TCC    G + CCP
Sbjct:  509 ALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPW-----------LTKVPALPFD-----------GTHSICDDTHTCPSGTTCCPGEGGGWRCCP 618

[Close]

BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832])

HSP 1 Score: 76.2554 bits (186), Expect = 2.100e-15
Identity = 56/167 (33.53%), Postives = 69/167 (41.32%), Query Frame = 2

Query:  200 YDITTDGVTTFKQVDED----GCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHA-IKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +  + DG + F+  D       C  S   C +  TCC+   G   CC    A CCED  HCCP G +CD  + RC           VS    H  +K  P     R+       S+    VCPD   +C    TCC L  G YGCCP    +CC D   CCP    C
Sbjct:  116 FHCSADGKSCFQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRC-----------VSPTGTHTLLKKFPAQKTNRA------VSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 265

HSP 2 Score: 73.1738 bits (178), Expect = 2.555e-14
Identity = 46/143 (32.17%), Postives = 65/143 (45.45%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C ++   C +  TCC    GK  CC   NA+CC D  HCCP+ T CD    +C+ ++               +  +P Y V+            ++  CP+G       TCC L  G +GCCP++  VCC D   CCP G +C
Sbjct:  220 CPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNY----------TTDLLTKLPGYPVKEV-------KCDMEVSCPEG------YTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQC 339

HSP 3 Score: 71.2478 bits (173), Expect = 1.257e-13
Identity = 54/153 (35.29%), Postives = 70/153 (45.75%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            TT  Q+ + GC + +  C   +TCC +  G   CCQ  +AVCCED  HCCP G TC+ K + C             +  +  I+  P   +   P     E       C +G  C    TCC  + G + CCPY  GVCC D R CCP G  C
Sbjct:  445 TTPLQIGDIGC-DQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------EKDVDFIQ--PPVLLTLGPKVGNVE-------CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHC 574

HSP 4 Score: 70.8626 bits (172), Expect = 1.665e-13
Identity = 54/163 (33.13%), Postives = 68/163 (41.72%), Query Frame = 2

Query:  203 DITTDGVTTFKQVDEDGCKNSNKI-CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
            + TTD +T          K   ++ C E  TCC    G   CC +  AVCCED  HCCP G  C T+   C                   I  +P      +PLR     I   +  C D  +C    TCC L +G +GCCP    VCC D + CCP G  C+
Sbjct:  276 NYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTC----------------EMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCL 422

HSP 5 Score: 60.8474 bits (146), Expect = 3.457e-10
Identity = 41/145 (28.28%), Postives = 57/145 (39.31%), Query Frame = 2

Query:  248 DGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            DG   ++  C    +C +T  G   CC ++  V C D  HCCP+G  C    K C   S  P+                             +  G +  CPD        TCC++ +G +GCCP     CC D+  CCP+G  C
Sbjct:   71 DGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPLGAV--------------------------QCPGSQFECPDSA------TCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 183

HSP 6 Score: 55.0694 bits (131), Expect = 2.719e-8
Identity = 42/136 (30.88%), Postives = 53/136 (38.97%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C    TCC    G   CC    AVCC D  HCCP+G TC  +                 D  +  ++ IP    + +PL+           CP G       TCC    G + CC     VCC D++ CCP G  C
Sbjct:  383 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQGY-----------CQKGDTMVAGLEKIPAR--QTTPLQIGDIGCDQHTSCPVG------QTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 499

[Close]

BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832])

HSP 1 Score: 71.633 bits (174), Expect = 2.309e-14
Identity = 55/154 (35.71%), Postives = 72/154 (46.75%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            TT  Q+ + GC + +  C   +TCC +  G   CCQ  +AVCCED  HCCP G TC+ K + C             +  +  I+  P   +   P         + NV C +G  C    TCC  + G + CCPY  GVCC D R CCP G  C
Sbjct:   90 TTPLQIGDIGC-DQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------EKDVDFIQ--PPVLLTLGP--------KVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHC 219

[Close]

BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832])

HSP 1 Score: 62.3882 bits (150), Expect = 2.296e-11
Identity = 41/145 (28.28%), Postives = 57/145 (39.31%), Query Frame = 2

Query:  248 DGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            DG   ++  C    +C +T  G   CC ++  V C D  HCCP+G  C    K C   S  P+                             +  G +  CPD        TCC++ +G +GCCP     CC D+  CCP+G  C
Sbjct:   58 DGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPLGAV--------------------------QCPGSQFECPDSA------TCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170

HSP 2 Score: 51.2174 bits (121), Expect = 1.995e-7
Identity = 38/125 (30.40%), Postives = 49/125 (39.20%), Query Frame = 2

Query:  200 YDITTDGVTTFKQVDED----GCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHA-IKAIPKYTVERSPLREWYESIGLKNVCPDG 559
            +  + DG + F+  D       C  S   C +  TCC+   G   CC    A CCED  HCCP G +CD  + RC           VS    H  +K  P     R+       S+    VCPD 
Sbjct:  103 FHCSADGKSCFQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRC-----------VSPTGTHTLLKKFPAQKTNRA------VSLPFSVVCPDA 210

[Close]

BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832])

HSP 1 Score: 53.9138 bits (128), Expect = 4.713e-8
Identity = 42/136 (30.88%), Postives = 53/136 (38.97%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C    TCC    G   CC    AVCC D  HCCP+G TC  +                 D  +  ++ IP    + +PL+           CP G       TCC    G + CC     VCC D++ CCP G  C
Sbjct:    5 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQGY-----------CQKGDTMVAGLEKIPAR--QTTPLQIGDIGCDQHTSCPVGQ------TCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 121

HSP 2 Score: 53.5286 bits (127), Expect = 7.083e-8
Identity = 44/135 (32.59%), Postives = 61/135 (45.19%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPY 625
            TT  Q+ + GC + +  C   +TCC +  G   CCQ  +AVCCED  HCCP G TC+ K + C             +  +  I+  P   +   P         + NV C +G  C    TCC  + G + CCPY
Sbjct:   67 TTPLQIGDIGC-DQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------EKDVDFIQ--PPVLLTLGP--------KVGNVECGEGHFCHDNQTCCKDSAGVWACCPY 177

[Close]

BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P28797|GRN_CAVPO (Progranulin OS=Cavia porcellus OX=10141 GN=GRN PE=1 SV=2)

HSP 1 Score: 83.5741 bits (205), Expect = 4.500e-17
Identity = 51/159 (32.08%), Postives = 72/159 (45.28%), Query Frame = 2

Query:  206 ITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            + + G+          C +S   C +  TCC+   G+  CC   NA+CC D  HCCP+ T CD +  RC+ Q+K              +  +P +TV       W      +  CP+G       TCC L +G +GCCP+   VCC D   CCP G +C
Sbjct:  206 VVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNKAKT----------LLTKLPSWTV-------WDVECDQEVSCPEG------QTCCRLQSGKWGCCPFPKAVCCEDHVHCCPEGFRC 341

HSP 2 Score: 78.1814 bits (191), Expect = 3.000e-15
Identity = 54/172 (31.40%), Postives = 73/172 (42.44%), Query Frame = 2

Query:  188 CIFVYDITTDGVTTFKQVD-----EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQ-SKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C + +  +TDG T  ++ D        C      C +  TCC    G   CC    A CCED  HCCP G +CD  + RC+      P+   +   + +   A     V    L     ++    +CPD   +C    TCCLL +G YGCCP    +CC D   CCP    C
Sbjct:   99 CPYGFHCSTDGGTCIQRPDIHLLGAVQCPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLP---AALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 267

HSP 3 Score: 72.4034 bits (176), Expect = 3.551e-13
Identity = 51/154 (33.12%), Postives = 67/154 (43.51%), Query Frame = 2

Query:  221 VTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            + +  Q  + GC + +  C   +TCC    G   CCQ  +AVCCED  HCCP G TC+ K + C            + D  H            +PL        +   C D   C    TCC  + G + CCP+  GVCC D+R CCP G  C
Sbjct:  444 LMSLSQTTDVGC-DQHASCPVGQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC----------EKAADGAHLA----------APLAVGSTGGVMDVACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHC 576

HSP 4 Score: 58.9214 bits (141), Expect = 9.182e-9
Identity = 42/141 (29.79%), Postives = 57/141 (40.43%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             S   C    +C +T  G   CC ++ A+ C D  HCCP G  C T    CI +             IH + A+              +  G +  CPD        TCC + +G +GCCP     CC D+  CCP+G  C
Sbjct:   62 QSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQRP-----------DIHLLGAV--------------QCPGGEFECPDSS------TCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 171

HSP 5 Score: 53.9138 bits (128), Expect = 5.184e-7
Identity = 44/125 (35.20%), Postives = 55/125 (44.00%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKN--VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCC 643
            C E +TCC  + GK  CC +  AVCCED  HCCPEG  C T+   C  Q    + W     K  A  + P       P         L++   C +   C     CC L +G +GCCP S G  C
Sbjct:  303 CPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTC-EQGLLQVPWA---QKTPAQPSRPSQPSPPGPPGPPSPPGPLRSEISCDEVVSCAPGNICCRLASGEWGCCPSSEGYLC 423

[Close]

BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P28799|GRN_HUMAN (Progranulin OS=Homo sapiens OX=9606 GN=GRN PE=1 SV=2)

HSP 1 Score: 82.0333 bits (201), Expect = 1.568e-16
Identity = 61/184 (33.15%), Postives = 83/184 (45.11%), Query Frame = 2

Query:  143 FLMKCPSLFLCALFL--CIFVYDITTDGVTTFKQVDEDGCKNSNKI-CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
             L  CP   +C L    C+   + TTD +T          K   ++ C +  TCC  + G   CC +T AVCCED  HCCP G TCDT+   C  Q    + W    +K  A  ++P             +++     C +   C    TCC LT+G +GCCP    VCC D + CCP G  C+
Sbjct:  243 HLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC-EQGPHQVPWM---EKAPAHLSLPD-----------PQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCV 411

HSP 2 Score: 80.8777 bits (198), Expect = 3.773e-16
Identity = 52/143 (36.36%), Postives = 69/143 (48.25%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
            + +  C   +TCC +  G   CCQ  +AVCCED  HCCP G TC+ K + C               +   + A P   + RSP       +G+K+V C +G  C    TCC      + CCPY  GVCC D+R CCP G +C 
Sbjct:  445 DQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC---------------EKEVVSAQPATFLARSP------HVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCA 566

HSP 3 Score: 73.9442 bits (180), Expect = 8.001e-14
Identity = 60/198 (30.30%), Postives = 80/198 (40.40%), Query Frame = 2

Query:  200 YDITTDGVTTFKQVDEDG-----CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNG-------RKCIPGSCI*FELY*RLFLDQIGFMKCD 757
            +  + DG + F++   +      C +S   C +  TCC+   G   CC    A CCED  HCCP G  CD  + RCI         T +     A K   + T     L         ++ CPDG       TCC L +G YGCCP     CC D   CCP          KC+       +L  +L    +G +KCD
Sbjct:  103 FHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCI---------TPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGS------TCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCD 285

HSP 4 Score: 73.1738 bits (178), Expect = 1.933e-13
Identity = 50/143 (34.97%), Postives = 66/143 (46.15%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C ++   C +  TCC    GK  CC   NA CC D  HCCP+ T CD    +C+  SKE       +     +  +P +TV             ++  CPDG       TCC L +G +GCCP++  VCC D   CCP G  C
Sbjct:  208 CPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCL--SKE-------NATTDLLTKLPAHTVGDV-------KCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTC 328

HSP 5 Score: 59.3066 bits (142), Expect = 8.626e-9
Identity = 40/140 (28.57%), Postives = 57/140 (40.71%), Query Frame = 2

Query:  266 NKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +  C    +C  T  G   CC +  AV C D  HCCP G  C    + C  +S         ++ + AI+                        CPD   +C  + TCC++ +G +GCCP     CC D+  CCP+G  C
Sbjct:   64 DAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRS--------GNNSVGAIQ------------------------CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171

[Close]

BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P23785|GRN_RAT (Progranulin OS=Rattus norvegicus OX=10116 GN=Grn PE=1 SV=3)

HSP 1 Score: 80.4925 bits (197), Expect = 5.857e-16
Identity = 55/163 (33.74%), Postives = 70/163 (42.94%), Query Frame = 2

Query:  194 FVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            F    T   V +F  V    C ++   C +  TCC    GK  CC   NA+CC D  HCCP+ T CD    +CI +          D     +  +P Y V             L+  CPDG       TCC L  G +GCCP++  VCC D   CCP G +C
Sbjct:  190 FPAQRTNRAVASFSVV----CPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK----------DYTTDLMTKLPGYPVNEV-------KCDLEVSCPDG------YTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQC 325

HSP 2 Score: 74.7146 bits (182), Expect = 4.539e-14
Identity = 54/162 (33.33%), Postives = 75/162 (46.30%), Query Frame = 2

Query:  203 DITTDGVTTFKQVDEDGCKNSNKI-CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
            D TTD +T       +  K   ++ C +  TCC    G   CC +T AVCCED  HCCP G  C T+   C     + + W     K+ A  ++P   + ++ +            C D   C    TCC L++G +GCCP    VCC D + CCP G KC+
Sbjct:  262 DYTTDLMTKLPGYPVNEVKCDLEVSCPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTCELGVLQ-VPWM---KKVTASLSLPDPQILKNDVP-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKCM 408

HSP 3 Score: 72.4034 bits (176), Expect = 3.289e-13
Identity = 50/145 (34.48%), Postives = 60/145 (41.38%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS-KEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C  S   C +  TCC+   G   CC    A CCED  HCCP G +CD  + RCI  +   P+           +K  P     R+             VCPD   +C    TCC L  G YGCCP    +CC D   CCP    C
Sbjct:  125 CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTHPL-----------LKKFPAQRTNRA-------VASFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 251

HSP 4 Score: 68.9366 bits (167), Expect = 5.155e-12
Identity = 54/154 (35.06%), Postives = 70/154 (45.45%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            TT  Q  + GC + +  C   +TCC +  G   CCQ  +AVCCED  HCCP G TC+ K + C   +                      +V+ S    +   +G  NV C  G  C    +CC  + G + CCPY  GVCC D R CCP G  C
Sbjct:  431 TTLLQHGDIGC-DQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDAG---------------------SVQPSMDLTFGSKVG--NVECGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHC 560

HSP 5 Score: 60.077 bits (144), Expect = 4.065e-9
Identity = 42/145 (28.97%), Postives = 59/145 (40.69%), Query Frame = 2

Query:  248 DGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            DG       C +  +C +T  G   CC ++  V C+D  HCCP G  C    K C           +SD  + A+                 +  G +  CPD        TCC++ +G +GCCP     CC D+  CCP+G  C
Sbjct:   58 DGSCQIRDHCPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQ---------ISDSLLGAV-----------------QCPGSQFECPDSA------TCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170

[Close]

BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P28798|GRN_MOUSE (Progranulin OS=Mus musculus OX=10090 GN=Grn PE=1 SV=2)

HSP 1 Score: 76.2554 bits (186), Expect = 1.376e-14
Identity = 56/167 (33.53%), Postives = 69/167 (41.32%), Query Frame = 2

Query:  200 YDITTDGVTTFKQVDED----GCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHA-IKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +  + DG + F+  D       C  S   C +  TCC+   G   CC    A CCED  HCCP G +CD  + RC           VS    H  +K  P     R+       S+    VCPD   +C    TCC L  G YGCCP    +CC D   CCP    C
Sbjct:  103 FHCSADGKSCFQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRC-----------VSPTGTHTLLKKFPAQKTNRA------VSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 252

HSP 2 Score: 73.1738 bits (178), Expect = 1.723e-13
Identity = 46/143 (32.17%), Postives = 65/143 (45.45%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C ++   C +  TCC    GK  CC   NA+CC D  HCCP+ T CD    +C+ ++               +  +P Y V+            ++  CP+G       TCC L  G +GCCP++  VCC D   CCP G +C
Sbjct:  207 CPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNY----------TTDLLTKLPGYPVKEV-------KCDMEVSCPEG------YTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQC 326

HSP 3 Score: 71.2478 bits (173), Expect = 8.091e-13
Identity = 54/153 (35.29%), Postives = 70/153 (45.75%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            TT  Q+ + GC + +  C   +TCC +  G   CCQ  +AVCCED  HCCP G TC+ K + C             +  +  I+  P   +   P     E       C +G  C    TCC  + G + CCPY  GVCC D R CCP G  C
Sbjct:  432 TTPLQIGDIGC-DQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------EKDVDFIQ--PPVLLTLGPKVGNVE-------CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHC 561

HSP 4 Score: 70.8626 bits (172), Expect = 1.062e-12
Identity = 54/163 (33.13%), Postives = 68/163 (41.72%), Query Frame = 2

Query:  203 DITTDGVTTFKQVDEDGCKNSNKI-CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
            + TTD +T          K   ++ C E  TCC    G   CC +  AVCCED  HCCP G  C T+   C                   I  +P      +PLR     I   +  C D  +C    TCC L +G +GCCP    VCC D + CCP G  C+
Sbjct:  263 NYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTC----------------EMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCL 409

HSP 5 Score: 60.8474 bits (146), Expect = 2.312e-9
Identity = 41/145 (28.28%), Postives = 57/145 (39.31%), Query Frame = 2

Query:  248 DGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            DG   ++  C    +C +T  G   CC ++  V C D  HCCP+G  C    K C   S  P+                             +  G +  CPD        TCC++ +G +GCCP     CC D+  CCP+G  C
Sbjct:   58 DGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPLGAV--------------------------QCPGSQFECPDSA------TCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170

HSP 6 Score: 55.0694 bits (131), Expect = 1.754e-7
Identity = 42/136 (30.88%), Postives = 53/136 (38.97%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C    TCC    G   CC    AVCC D  HCCP+G TC  +                 D  +  ++ IP    + +PL+           CP G       TCC    G + CC     VCC D++ CCP G  C
Sbjct:  370 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQGY-----------CQKGDTMVAGLEKIPAR--QTTPLQIGDIGCDQHTSCPVG------QTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486

[Close]

BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P80059|PMD1_LOCMI (Pars intercerebralis major peptide D1 OS=Locusta migratoria OX=7004 PE=1 SV=1)

HSP 1 Score: 50.0618 bits (118), Expect = 2.361e-7
Identity = 25/52 (48.08%), Postives = 30/52 (57.69%), Query Frame = 2

Query:  263 SNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIH 418
            + K C   +TCC T  G+  CC Y   VCC D  HCCP GT CD  ++RCI 
Sbjct:    3 TEKTCPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCIQ 54

[Close]

BLAST of Granulin b vs. TrEMBL
Match: A0A023GCS2 (Putative granulin (Fragment) OS=Amblyomma triste OX=251400 PE=2 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 3.032e-21
Identity = 58/169 (34.32%), Postives = 83/169 (49.11%), Query Frame = 2

Query:  176 ALFLCIFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            A+ + +  + I +    ++ Q  EDG      +C ++ TCC    G   CC Y +A CC+D  HCCP    CD  N  C+H S +   +        A+  +P  ++ R   R+    + L   CPDG  C    TCCLL++G YGCCPY    CC D  +CCP G +C
Sbjct:    5 AVIVLVAAFAIASGARVSYNQC-EDG-----NLCPDKTTCCQKVDGNWACCPYESAQCCQDGVHCCPSTYRCDVTNGTCVHASSQERLFGA------ALAPVPPVSI-RDRQRDDVSKLELVP-CPDGSYCNDGQTCCLLSSGGYGCCPYVHAECCSDHASCCPEGYRC 159

[Close]

BLAST of Granulin b vs. TrEMBL
Match: A0A226F5G2 (Granulins OS=Folsomia candida OX=158441 GN=Fcan01_03077 PE=4 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 3.947e-20
Identity = 57/177 (32.20%), Postives = 85/177 (48.02%), Query Frame = 2

Query:  161 SLFLCALFLCIFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCI-HQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGL-KNVCPDGGK-CTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             +F+  L +CI +             V  D C +    C + +TCC    G   CC Y  A CC D  HCCP G+ CDT + RCI ++  EP  WT+        + + +  +    +   + +  + K +C  G + C    TCC L +G +GCCP+   +CCPDK  CCP+G+ C
Sbjct:    6 GVFVVLLHICILI-----------AFVSGDTCPDHKTRCSKTQTCCSDNRGGYGCCPYPGATCCNDGQHCCPHGSKCDTVHSRCIPNEVSEPEWWTMIYKSFTREEWLAQNLITEDGVDSGHNATMVDKKICGGGEQTCPDKYTCCALASGGWGCCPFDGAMCCPDKIHCCPHGKTC 171

HSP 2 Score: 56.225 bits (134), Expect = 4.809e-6
Identity = 31/73 (42.47%), Postives = 39/73 (53.42%), Query Frame = 2

Query:  206 ITTDGVTTFKQ---VDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCI 415
            IT DGV +      VD+  C    + C ++ TCC    G   CC +  A+CC D  HCCP G TCD K KRC+
Sbjct:  107 ITEDGVDSGHNATMVDKKICGGGEQTCPDKYTCCALASGGWGCCPFDGAMCCPDKIHCCPHGKTCDDKGKRCV 179

[Close]

BLAST of Granulin b vs. TrEMBL
Match: A0A131XWJ6 (Putative granulin (Fragment) OS=Ixodes ricinus OX=34613 PE=2 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 4.116e-20
Identity = 52/140 (37.14%), Postives = 71/140 (50.71%), Query Frame = 2

Query:  263 SNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +  +C ++ TCC+   G+  CC Y  AVCC D  HCCPEG  C+  N  C       ++ + +  K+  +      + +  P     ES+     CPDG  C    TCCLL+ G YGCCPY   VCC D  +CCP G +C
Sbjct:   11 NGALCPDRTTCCLQNSGQYGCCPYQFAVCCSDHLHCCPEGYHCNMSNGTC-------LQISTTTKKVETLLTPMVLSPQLGPNAPAVESV----RCPDGNFCQDGQTCCLLSGGRYGCCPYPHAVCCSDHASCCPEGYRC 139

HSP 2 Score: 56.9954 bits (136), Expect = 3.079e-6
Identity = 40/124 (32.26%), Postives = 57/124 (45.97%), Query Frame = 2

Query:  239 VDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHY 610
            V+   C + N  C + +TCC+   G+  CC Y +AVCC D + CCPEG  C      C+            +  +  +K +   T+  S L E      ++  CPDG  C    TCCLL+ G Y
Sbjct:   90 VESVRCPDGN-FCQDGQTCCLLSGGRYGCCPYPHAVCCSDHASCCPEGYRCKVSTHSCV----------AGNSTLPMLKKLD--TIGGSSLDEPAPVESVR--CPDGNFCQDGQTCCLLSGGRY 198

[Close]

BLAST of Granulin b vs. TrEMBL
Match: A0A443S242 (Uncharacterized protein OS=Leptotrombidium deliense OX=299467 GN=B4U80_08821 PE=4 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 9.329e-20
Identity = 60/144 (41.67%), Postives = 77/144 (53.47%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +S++   +  TCC  + G   CC   NAVCC D  HCCPEGT CD KN  C+H+ ++ +  ++S       K+I   TVE               +CPDG  +C    TCC L +G YGCCPY  GVCC D+  CCPNG  C
Sbjct:   22 CPDSSQCVDDDSTCCKLRSGHYGCCPLPNAVCCTDGFHCCPEGTKCDEKNGTCVHEMQQ-IRRSLS-------KSISLNTVENI-------------ICPDGKEQCLDSQTCCELQSGQYGCCPYEKGVCCSDEEHCCPNGFAC 144

HSP 2 Score: 89.3521 bits (220), Expect = 8.490e-18
Identity = 55/159 (34.59%), Postives = 76/159 (47.80%), Query Frame = 2

Query:  227 TFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
            +   V+   C +  + C + +TCC  + G+  CC Y   VCC D  HCCP G  CD ++ RCIHQ     E+  +         +PK       +   + S     +CPD   +C    TCC +  G +GCCP    VCC DK  CCP+G KC  G C+
Sbjct:   90 SLNTVENIICPDGKEQCLDSQTCCELQSGQYGCCPYEKGVCCSDEEHCCPNGFACDVRHSRCIHQ-----EFNTA--------IVPK-------MLARFNSTISSVICPDKTSQCPDGNTCCQMEGGEWGCCPLESAVCCEDKVHCCPHGTKCAEGGCV 228

[Close]

BLAST of Granulin b vs. TrEMBL
Match: A0A0B2W2D5 (Granulin (Fragment) OS=Toxocara canis OX=6265 GN=Grn PE=4 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 2.917e-19
Identity = 58/148 (39.19%), Postives = 70/148 (47.30%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSC 697
            C +    C +  TCC    G+  CC   +AVCCED  HCCPEGT CD ++  C  Q +  + W     K HA K   K  V   P           N+C DG KCT    CC   +G Y CCP   G+CC   + CCP G KC  G C
Sbjct:  136 CPDHRTKCDDDATCCALGQGRYGCCPMPDAVCCEDHLHCCPEGTECDVEHGMCHSQERGAIMWW---KKQHAAKIGQKAAVRTKP---------ASNICTDGTKCTATNKCCEAEDGSYSCCPLKNGLCCKGAQFCCPRGYKCDEGQC 271

HSP 2 Score: 82.8037 bits (203), Expect = 1.349e-14
Identity = 57/167 (34.13%), Postives = 72/167 (43.11%), Query Frame = 2

Query:  194 FVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKN---VCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             +  + +  +     V    C +    C +  TCC+   G   CC   NAVCCED  HCCPE T CD + +RC           VS D +             S +R   ++  +K    VCPD   KC    TCC L  G YGCCP    VCC D   CCP G +C
Sbjct:   38 LLVSLVSAVIVAVSIVKARVCPDGRSACDDTTTCCLADEGVYGCCPLPNAVCCEDYLHCCPEKTRCDVQAQRC-----------VSPDGL------------SSQIRRKQQARQIKAKFVVCPDHRTKCDDDATCCALGQGRYGCCPMPDAVCCEDHLHCCPEGTEC 181

HSP 3 Score: 56.9954 bits (136), Expect = 9.267e-6
Identity = 44/143 (30.77%), Postives = 58/143 (40.56%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNG----HYGCCPYSFGVCCPDKRTCCPNGRKCIPG 691
            C     CC  + G   CC   N +CC+    CCP G  CD    +C    +E +              + K  +E SP  E  +   +  +C DG  C     CC   N     +Y CCP   GVCC  + TCCP G +C  G
Sbjct:  228 CTATNKCCEAEDGSYSCCPLKNGLCCKGAQFCCPRGYKCD--EGQCYRDDEETV--------------VSKLAIETSPASEDTDEDSV--LCADGSACPSTNKCCRSKNNDGSVYYSCCPLRKGVCC--EHTCCPRGYQCAEG 350

[Close]

BLAST of Granulin b vs. Ensembl Cavefish
Match: grnb (granulins-like [Source:NCBI gene;Acc:103046308])

HSP 1 Score: 81.2629 bits (199), Expect = 3.501e-17
Identity = 52/138 (37.68%), Postives = 69/138 (50.00%), Query Frame = 2

Query:  272 ICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +C +  TCC T  G   CC   NA CC D  HCC EGT CD ++ +C++++   ++W                 V R P+R+   S+    VCPD   +C    TCC L +G +GCCP    VCC DK  CCP G  C
Sbjct:   25 MCDDGNTCCQTPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHT-LDW-----------------VMRVPIRQ--PSLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTC 142

HSP 2 Score: 80.8777 bits (198), Expect = 4.871e-17
Identity = 53/148 (35.81%), Postives = 64/148 (43.24%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV----CPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +    C +  TCC    G   CC   NAVCCED  HCCP+GTTCD  + +C+               +   +  P Y       R+    + L +     CPD    C    TCC L NG YGCCP    VCC D   CCP G  C
Sbjct:   97 CPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSML---------GSVPLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSC 235

HSP 3 Score: 70.8626 bits (172), Expect = 1.123e-13
Identity = 52/164 (31.71%), Postives = 72/164 (43.90%), Query Frame = 2

Query:  212 TDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS-KEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
            ++G+      D D C +    C +  TCC    G   CC    AVCC D  HCCP+GT+CD  + +C+  +  EP+   +S      ++   K TVE  P             C +   C    TCC   +G + CCP    VCC D   CCP G  C   +C+
Sbjct:  177 SNGLDLADSNDVD-CPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSP----VVRV--KVTVESVP-------------CNESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCV 320

HSP 4 Score: 69.707 bits (169), Expect = 2.732e-13
Identity = 50/144 (34.72%), Postives = 64/144 (44.44%), Query Frame = 2

Query:  260 NSNKICGEQKTCC-MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYE-SIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            ++   C    TCC M K  K  CC    AVCC D  HCCP   TCDT    C+    E                IP +  + + + +  E + G+ +V C    +C    TCC LT G +GCCP+   VCC D   CCP G  C
Sbjct:  528 DAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTCLKGHLE----------------IPWFKKQEAKVTQGSEVAHGVADVQCDSTARCPTGSTCCRLTTGQWGCCPHVQAVCCDDHVHCCPAGYTC 655

HSP 5 Score: 69.707 bits (169), Expect = 2.972e-13
Identity = 45/143 (31.47%), Postives = 62/143 (43.36%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIP 688
            +S   C    TCC    G+  CC +  AVCC+D  HCCP G TCD +   C+  S            +H +     +T  +  +           +C     CT   TCC L++  + CCP+   VCC D + CCP G  C P
Sbjct:  612 DSTARCPTGSTCCRLTTGQWGCCPHVQAVCCDDHVHCCPAGYTCDLQAGTCLRTS-----------TLHTVALTLVHTHTKEQV-----------MCDATSHCTESQTCCKLSDTEWACCPFKQAVCCKDMKHCCPVGYVCDP 732

HSP 6 Score: 65.855 bits (159), Expect = 5.939e-12
Identity = 43/142 (30.28%), Postives = 57/142 (40.14%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTN-GHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +    C    TCC  K G   CC    AVCC+D  HCCP+G  CD  ++ C H     M W      + ++         ++        +  K+ C     C    TCC +     +GCCP    VCC D   CCPN   C
Sbjct:  432 DETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQPALQSMTQQSNANA-KAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTC 572

HSP 7 Score: 65.4698 bits (158), Expect = 7.155e-12
Identity = 51/190 (26.84%), Postives = 71/190 (37.37%), Query Frame = 2

Query:  137 EVFLMKCPSLFLCALFLCIFVYDITT--------DGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            E  +  CP   +CA   C+   D+ T          +    Q   + C +    C +  TCC  + G   CC    AVCCED  HCCP  T C+     C          T     +  ++  P  ++  +            + C +   C    TCC   +G + CCP    VCC D   CCP G KC
Sbjct:  302 EDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKC-DPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTC----DSAFSGTAGQLSVPWVRKTPATSLPPA-----------NDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKC 475

HSP 8 Score: 47.7506 bits (112), Expect = 6.352e-6
Identity = 31/94 (32.98%), Postives = 43/94 (45.74%), Query Frame = 2

Query:  155 CPSLFLCALFL--CIFVYDITTDGVTTFK-QVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSK 427
            CP+ + C L    C+    + T  +T       E    ++   C E +TCC     +  CC +  AVCC+DM HCCP G  CD K K C   + 
Sbjct:  649 CPAGYTCDLQAGTCLRTSTLHTVALTLVHTHTKEQVMCDATSHCTESQTCCKLSDTEWACCPFKQAVCCKDMKHCCPVGYVCDPKAKGCARATS 742

[Close]

Query:  272 ICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +C +  TCC T  G   CC   NA CC D  HCC EGT CD ++ +C++++   ++W                 V R P+R+   S+    VCPD   +C    TCC L +G +GCCP    VCC DK  CCP G  C
Sbjct:   25 MCDDGNTCCQTPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHT-LDW-----------------VMRVPIRQ--PSLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTC 142

HSP 2 Score: 80.8777 bits (198), Expect = 4.871e-17
Identity = 53/148 (35.81%), Postives = 64/148 (43.24%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV----CPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +    C +  TCC    G   CC   NAVCCED  HCCP+GTTCD  + +C+               +   +  P Y       R+    + L +     CPD    C    TCC L NG YGCCP    VCC D   CCP G  C
Sbjct:   97 CPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSML---------GSVPLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSC 235

HSP 3 Score: 70.8626 bits (172), Expect = 1.123e-13
Identity = 52/164 (31.71%), Postives = 72/164 (43.90%), Query Frame = 2

Query:  212 TDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS-KEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
            ++G+      D D C +    C +  TCC    G   CC    AVCC D  HCCP+GT+CD  + +C+  +  EP+   +S      ++   K TVE  P             C +   C    TCC   +G + CCP    VCC D   CCP G  C   +C+
Sbjct:  177 SNGLDLADSNDVD-CPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSP----VVRV--KVTVESVP-------------CNESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCV 320

HSP 4 Score: 69.707 bits (169), Expect = 2.732e-13
Identity = 50/144 (34.72%), Postives = 64/144 (44.44%), Query Frame = 2

Query:  260 NSNKICGEQKTCC-MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYE-SIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            ++   C    TCC M K  K  CC    AVCC D  HCCP   TCDT    C+    E                IP +  + + + +  E + G+ +V C    +C    TCC LT G +GCCP+   VCC D   CCP G  C
Sbjct:  528 DAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTCLKGHLE----------------IPWFKKQEAKVTQGSEVAHGVADVQCDSTARCPTGSTCCRLTTGQWGCCPHVQAVCCDDHVHCCPAGYTC 655

HSP 5 Score: 69.707 bits (169), Expect = 2.972e-13
Identity = 45/143 (31.47%), Postives = 62/143 (43.36%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIP 688
            +S   C    TCC    G+  CC +  AVCC+D  HCCP G TCD +   C+  S            +H +     +T  +  +           +C     CT   TCC L++  + CCP+   VCC D + CCP G  C P
Sbjct:  612 DSTARCPTGSTCCRLTTGQWGCCPHVQAVCCDDHVHCCPAGYTCDLQAGTCLRTS-----------TLHTVALTLVHTHTKEQV-----------MCDATSHCTESQTCCKLSDTEWACCPFKQAVCCKDMKHCCPVGYVCDP 732

HSP 6 Score: 65.855 bits (159), Expect = 5.939e-12
Identity = 43/142 (30.28%), Postives = 57/142 (40.14%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTN-GHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +    C    TCC  K G   CC    AVCC+D  HCCP+G  CD  ++ C H     M W      + ++         ++        +  K+ C     C    TCC +     +GCCP    VCC D   CCPN   C
Sbjct:  432 DETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQPALQSMTQQSNANA-KAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTC 572

HSP 7 Score: 65.4698 bits (158), Expect = 7.155e-12
Identity = 51/190 (26.84%), Postives = 71/190 (37.37%), Query Frame = 2

Query:  137 EVFLMKCPSLFLCALFLCIFVYDITT--------DGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            E  +  CP   +CA   C+   D+ T          +    Q   + C +    C +  TCC  + G   CC    AVCCED  HCCP  T C+     C          T     +  ++  P  ++  +            + C +   C    TCC   +G + CCP    VCC D   CCP G KC
Sbjct:  302 EDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKC-DPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTC----DSAFSGTAGQLSVPWVRKTPATSLPPA-----------NDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKC 475

HSP 8 Score: 47.7506 bits (112), Expect = 6.352e-6
Identity = 31/94 (32.98%), Postives = 43/94 (45.74%), Query Frame = 2

Query:  155 CPSLFLCALFL--CIFVYDITTDGVTTFK-QVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSK 427
            CP+ + C L    C+    + T  +T       E    ++   C E +TCC     +  CC +  AVCC+DM HCCP G  CD K K C   + 
Sbjct:  649 CPAGYTCDLQAGTCLRTSTLHTVALTLVHTHTKEQVMCDATSHCTESQTCCKLSDTEWACCPFKQAVCCKDMKHCCPVGYVCDPKAKGCARATS 742

[Close]

BLAST of Granulin b vs. Ensembl Cavefish
Match: ENSAMXT00000034465.1 (pep primary_assembly:Astyanax_mexicanus-2.0:23:26782099:26792241:-1 gene:ENSAMXG00000014237.2 transcript:ENSAMXT00000034465.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.7146 bits (182), Expect = 3.584e-15
Identity = 48/146 (32.88%), Postives = 64/146 (43.84%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIH-----QSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +S+  C +  TCC T  G+  CC Y    CC D  HCCP G  CD+ + RC+      +S  P    +  +K +  +  P   V   P  +     G+   C     C    TCC    G +GCCPY  G CC D + CC  G  C
Sbjct:  213 DSSYTCPDGTTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHCDSTSTRCMQGALSIRSSSPQPAMLIQNKQYLQEDQPAPLVPLEPALDNQVQEGVIR-CNGRFYCPAEYTCCQAPTGEWGCCPYKLGQCCKDGKHCCEFGYNC 357

HSP 2 Score: 73.9442 bits (180), Expect = 7.857e-15
Identity = 53/154 (34.42%), Postives = 70/154 (45.45%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIH-----QSKEPMEWTVSDDKIHAIKAI---PKYTV-----ERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +S+  C +  TCC T  G+  CC Y    CC D  HCCP G  CD+ + RC+      +S  P    +  +K  A++     P  TV     + SP+     S      CPDG       TCC    G + CCPY+ G CC D   CCP+G  C
Sbjct:  113 DSSYTCPDGTTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHCDSTSTRCMQGALSIRSSSPQPAMLIQNKQKAVEETEEKPSATVVELSDDSSPMVHCDSSY----TCPDG------TTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHC 256

HSP 3 Score: 67.781 bits (164), Expect = 1.098e-12
Identity = 52/171 (30.41%), Postives = 75/171 (43.86%), Query Frame = 2

Query:  191 IFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKR-CIHQSKE------PMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            I V  +   G+ +      DG       C +  TCC+T  G   CC   NAVCC    +CCP+G  CD  + + C+ Q         P++  V + +     ++ + + + SP+     S      CPDG       TCC    G + CCPY+ G CC D   CCP+G  C
Sbjct:    2 IVVLVLLMAGLVSSDITCPDG-----HTCPDNNTCCLTDQGY-ACCPAPNAVCCPGQEYCCPQGYKCDPSSPQGCVKQGLPWYDIFMPLQKAVEETEEKPSTSVVELSDDSSPMVHCDSSY----TCPDG------TTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHC 156

HSP 4 Score: 48.1358 bits (113), Expect = 3.745e-6
Identity = 26/50 (52.00%), Postives = 27/50 (54.00%), Query Frame = 2

Query:  545 VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGS 694
             CPDG  C    TCCL   G Y CCP    VCCP +  CCP G KC P S
Sbjct:   18 TCPDGHTCPDNNTCCLTDQG-YACCPAPNAVCCPGQEYCCPQGYKCDPSS 66

[Close]

BLAST of Granulin b vs. Ensembl Cavefish
Match: ENSAMXT00000030959.1 (pep primary_assembly:Astyanax_mexicanus-2.0:23:26782099:26792241:-1 gene:ENSAMXG00000014237.2 transcript:ENSAMXT00000030959.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.7146 bits (182), Expect = 3.584e-15
Identity = 48/146 (32.88%), Postives = 64/146 (43.84%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIH-----QSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +S+  C +  TCC T  G+  CC Y    CC D  HCCP G  CD+ + RC+      +S  P    +  +K +  +  P   V   P  +     G+   C     C    TCC    G +GCCPY  G CC D + CC  G  C
Sbjct:  213 DSSYTCPDGTTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHCDSTSTRCMQGALSIRSSSPQPAMLIQNKQYLQEDQPAPLVPLEPALDNQVQEGVIR-CNGRFYCPAEYTCCQAPTGEWGCCPYKLGQCCKDGKHCCEFGYNC 357

HSP 2 Score: 73.1738 bits (178), Expect = 1.231e-14
Identity = 52/150 (34.67%), Postives = 67/150 (44.67%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIH-----QSKEPMEWTVSDDKIHAIKAI---PKYT-VERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +S+  C +  TCC T  G+  CC Y    CC D  HCCP G  CD+ + RC+      +S  P    +  +K  A++     P  T VE S              CPDG       TCC    G + CCPY+ G CC D   CCP+G  C
Sbjct:  113 DSSYTCPDGTTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHCDSTSTRCMQGALSIRSSSPQPAMLIQNKQKAVEETEEKPSATLVELSGDSSPMVHCDSSYTCPDG------TTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHC 256

HSP 3 Score: 67.781 bits (164), Expect = 9.898e-13
Identity = 52/171 (30.41%), Postives = 75/171 (43.86%), Query Frame = 2

Query:  191 IFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKR-CIHQSKE------PMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            I V  +   G+ +      DG       C +  TCC+T  G   CC   NAVCC    +CCP+G  CD  + + C+ Q         P++  V + +     ++ + + + SP+     S      CPDG       TCC    G + CCPY+ G CC D   CCP+G  C
Sbjct:    2 IVVLVLLMAGLVSSDITCPDG-----HTCPDNNTCCLTDQGY-ACCPAPNAVCCPGQEYCCPQGYKCDPSSPQGCVKQGLPWYDIFMPLQKAVEETEEKPSTSVVELSDDSSPMVHCDSSY----TCPDG------TTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHC 156

HSP 4 Score: 47.7506 bits (112), Expect = 4.179e-6
Identity = 26/50 (52.00%), Postives = 27/50 (54.00%), Query Frame = 2

Query:  545 VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGS 694
             CPDG  C    TCCL   G Y CCP    VCCP +  CCP G KC P S
Sbjct:   18 TCPDGHTCPDNNTCCLTDQG-YACCPAPNAVCCPGQEYCCPQGYKCDPSS 66

[Close]

BLAST of Granulin b vs. Ensembl Cavefish
Match: ENSAMXT00000057729.1 (pep primary_assembly:Astyanax_mexicanus-2.0:23:26782099:26792241:-1 gene:ENSAMXG00000014237.2 transcript:ENSAMXT00000057729.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.7146 bits (182), Expect = 3.584e-15
Identity = 48/146 (32.88%), Postives = 64/146 (43.84%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIH-----QSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +S+  C +  TCC T  G+  CC Y    CC D  HCCP G  CD+ + RC+      +S  P    +  +K +  +  P   V   P  +     G+   C     C    TCC    G +GCCPY  G CC D + CC  G  C
Sbjct:  213 DSSYTCPDGTTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHCDSTSTRCMQGALSIRSSSPQPAMLIQNKQYLQEDQPAPLVPLEPALDNQVQEGVIR-CNGRFYCPAEYTCCQAPTGEWGCCPYKLGQCCKDGKHCCEFGYNC 357

HSP 2 Score: 73.1738 bits (178), Expect = 1.231e-14
Identity = 52/150 (34.67%), Postives = 67/150 (44.67%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIH-----QSKEPMEWTVSDDKIHAIKAI---PKYT-VERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +S+  C +  TCC T  G+  CC Y    CC D  HCCP G  CD+ + RC+      +S  P    +  +K  A++     P  T VE S              CPDG       TCC    G + CCPY+ G CC D   CCP+G  C
Sbjct:  113 DSSYTCPDGTTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHCDSTSTRCMQGALSIRSSSPQPAMLIQNKQKAVEETEEKPSATLVELSGDSSPMVHCDSSYTCPDG------TTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHC 256

HSP 3 Score: 67.781 bits (164), Expect = 9.898e-13
Identity = 52/171 (30.41%), Postives = 75/171 (43.86%), Query Frame = 2

Query:  191 IFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKR-CIHQSKE------PMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            I V  +   G+ +      DG       C +  TCC+T  G   CC   NAVCC    +CCP+G  CD  + + C+ Q         P++  V + +     ++ + + + SP+     S      CPDG       TCC    G + CCPY+ G CC D   CCP+G  C
Sbjct:    2 IVVLVLLMAGLVSSDITCPDG-----HTCPDNNTCCLTDQGY-ACCPAPNAVCCPGQEYCCPQGYKCDPSSPQGCVKQGLPWYDIFMPLQKAVEETEEKPSTSVVELSDDSSPMVHCDSSY----TCPDG------TTCCRTPYGRWACCPYNMGQCCRDGIHCCPHGYHC 156

HSP 4 Score: 47.7506 bits (112), Expect = 4.179e-6
Identity = 26/50 (52.00%), Postives = 27/50 (54.00%), Query Frame = 2

Query:  545 VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGS 694
             CPDG  C    TCCL   G Y CCP    VCCP +  CCP G KC P S
Sbjct:   18 TCPDGHTCPDNNTCCLTDQG-YACCPAPNAVCCPGQEYCCPQGYKCDPSS 66

[Close]

BLAST of Granulin b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009302.1 (pep scaffold:Pmarinus_7.0:GL483232:1183:11161:1 gene:ENSPMAG00000008413.1 transcript:ENSPMAT00000009302.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.7962 bits (190), Expect = 9.873e-17
Identity = 50/136 (36.76%), Postives = 60/136 (44.12%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +Q TCC T  G   CC    AVCC+D  HCCPEGTTC+     C  Q +  + W+    K  A   +       +  R           CPDG       TCC L  G +GCCP     CC D   CCP+G  C
Sbjct:  610 CPDQTTCCKTGTGDWGCCPLVKAVCCDDHEHCCPEGTTCNVPAGSC-DQGQLSLPWS---SKTPARTRLTALLPASAAARGGSVRCDSAYACPDG------TTCCQLPQGQWGCCPLPLATCCSDFVHCCPSGYTC 735

HSP 2 Score: 75.485 bits (184), Expect = 6.981e-16
Identity = 48/136 (35.29%), Postives = 63/136 (46.32%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            CG+  TCC    G+  CC   +AVCC D  HCCP+ T CD K  +C+H  K  + W                 V + P ++    +     C     C+   TCC+L +G +GCCP    VCC DK  CCP G  C
Sbjct:   67 CGDDATCCPLASGQYGCCSLEDAVCCSDYLHCCPKNTMCDLKLGKCVH-GKLSIPW-----------------VSKYPSKQAASDV----QCDAFTSCSDQNTCCILPSGQWGCCPLPKAVCCDDKEHCCPEGTIC 180

HSP 3 Score: 73.9442 bits (180), Expect = 2.344e-15
Identity = 58/183 (31.69%), Postives = 85/183 (46.45%), Query Frame = 2

Query:  143 FLMKCPSLFLCALFLCIFVY-DITTDGVTTF--KQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +L  CP   +C L L   V+  ++   V+ +  KQ   D   ++   C +Q TCC+   G+  CC    AVCC+D  HCCPEGT C+  ++ C H +   + W+     +       + T E + + +  + +G    CPDG       TCC    G + CCP    VCC D   CCP G  C
Sbjct:   95 YLHCCPKNTMCDLKLGKCVHGKLSIPWVSKYPSKQAASDVQCDAFTSCSDQNTCCILPSGQWGCCPLPKAVCCDDKEHCCPEGTICNVTSQTCNHAALS-LPWSTKTPAL-------RMTGEPNDV-QCDDLVG----CPDGN------TCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTC 258

HSP 4 Score: 72.0182 bits (175), Expect = 9.746e-15
Identity = 47/141 (33.33%), Postives = 63/141 (44.68%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +    C +  TCC T  G   CC    AVCC+D  HCCP+GTTC+   + C  Q    + W+    K  A++   +  V                +C D   C    TCC + +G +GCCP    VCC D + CCP G  C
Sbjct:  293 DDQSSCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTC-DQGTLSLPWST---KTPALRVAGEPNVV---------------ICDDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTC 414

HSP 5 Score: 70.4774 bits (171), Expect = 3.025e-14
Identity = 48/141 (34.04%), Postives = 62/141 (43.97%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +    C +  TCC    G   CC    AVCC+D  HCCPEGTTC+   +RC  +    + W+    K  A++   +  V                +C D   C    TCC L +G +GCCP    VCC D   CCP G  C
Sbjct:  371 DDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTCNLPVERC-DKGTLSLPWST---KTPALRVAGEPNVV---------------ICDDQFSCPDGNTCCKLPSGDWGCCPLVKAVCCDDHEHCCPQGTTC 492

HSP 6 Score: 68.5514 bits (166), Expect = 1.538e-13
Identity = 46/136 (33.82%), Postives = 60/136 (44.12%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +  TCC    G   CC    AVCC+D  HCCP+GTTC+   + C  Q    + W+    K  A++   +  V                +C D   C    TCC + +G +GCCP    VCC D   CCP G  C
Sbjct:  454 CPDGNTCCKLPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTC-DQGTLSLPWST---KTPALRVAGEPNVV---------------ICDDQFSCPDGDTCCKMPSGDWGCCPLVKAVCCDDHEHCCPQGTTC 570

HSP 7 Score: 67.3958 bits (163), Expect = 3.307e-13
Identity = 46/136 (33.82%), Postives = 58/136 (42.65%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +  TCC T  G   CC    AVCC+D  HCCP+GTTC+   + C  Q    + W+    K  A++   +  V                +C D   C    TCC    G + CCP    VCC D   CCP G  C
Sbjct:  220 CPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTC-DQGTLSLPWST---KTPALRVAGEPNVV---------------ICDDQSSCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTC 336

HSP 8 Score: 65.0846 bits (157), Expect = 2.072e-12
Identity = 52/143 (36.36%), Postives = 65/143 (45.45%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC-IP-GSC 697
            C +  TCC    G   CC    AVCC+D  HCCP+GTTC+   + C              DK     ++P ++ +   LR   E   +K  C D   C    TCC    G +GCCP    VCC D   CCP G  C +P GSC
Sbjct:  532 CPDGDTCCKMPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTC--------------DK--GALSLP-WSTKTPALRVAGEPNDVK--CDDQVSCPDQTTCCKTGTGDWGCCPLVKAVCCDDHEHCCPEGTTCNVPAGSC 655

HSP 9 Score: 63.1586 bits (152), Expect = 8.752e-12
Identity = 41/115 (35.65%), Postives = 48/115 (41.74%), Query Frame = 2

Query:  338 NAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             AVCC D  HCCP GT CD  +  C  + K  + W         ++  P +T      R           CPDG  C    TCC L +G YGCC     VCC D   CCP    C
Sbjct:    1 QAVCCSDGLHCCPSGTVCDLAHGMC-QKGKISVPW---------LEKTPTFTPRTWRWRLARSLAVRPPQCPDGTSCGDDATCCPLASGQYGCCSLEDAVCCSDYLHCCPKNTMC 105

[Close]

BLAST of Granulin b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001039.1 (pep scaffold:Pmarinus_7.0:GL484091:11570:24665:-1 gene:ENSPMAG00000000936.1 transcript:ENSPMAT00000001039.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.0694 bits (131), Expect = 3.922e-9
Identity = 41/147 (27.89%), Postives = 60/147 (40.82%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
               + C   +TCC ++ G   CC    A CC D  HCCP  T C    + C   S+             A+  +   + E+   ++ Y  +     C  G  C  + TCC    G +GCC      CC D   CCP+  +C+ G C+
Sbjct:   69 GGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRLCSRSSE-------------ALSVLDYLSREQ---QDGYNVV----HCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCV 195

HSP 2 Score: 53.5286 bits (127), Expect = 1.485e-8
Identity = 47/182 (25.82%), Postives = 70/182 (38.46%), Query Frame = 2

Query:  155 CPSLFLCALFLCI----FVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
            CPS+  C +  C+     +  +  +   +    D        + C   +TCC ++ G   CC    A CC D  HCCP G + D K + C++ +               I  + K      P       +G   V C  G  C  + TCC    G +GCC      CC D   CCP+  +C+
Sbjct:  335 CPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNVVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSGASGDLKGQ-CVNSAA-------------LIPWLKKEAALSGP-------VGDNLVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCL 495

HSP 3 Score: 51.9878 bits (123), Expect = 5.256e-8
Identity = 48/187 (25.67%), Postives = 71/187 (37.97%), Query Frame = 2

Query:  155 CPSLFLCALFLCI----FVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
            CPS+  C +  C+     +  +  +   +    D        + C   +TCC ++ G   CC    A CC D  HCCP  T C     +C++ +               I  + K      P       +G   V C  G  C  + TCC    G +GCC      CC D   CCP+  +C+ G C+
Sbjct:  183 CPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNVVHCGGGQYCRRWQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRCLV--GQCVNSAA-------------LIPWLKKEAALSGP-------VGDNLVHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVGQCV 347

HSP 4 Score: 48.9062 bits (115), Expect = 4.611e-7
Identity = 37/142 (26.06%), Postives = 50/142 (35.21%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCI 685
               + C   +TCC ++ G   CC    A CC D  HCCP  T C    + C   S+       S    HA+    +    R                        + TCC    G +GCC      CC D   CCP+  +C+
Sbjct:  451 GGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLCSRSSEALSGVAGSSTLSHALPYDSRVYCRR------------------------WQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRCL 568

[Close]

BLAST of Granulin b vs. Ensembl Nematostella
Match: EDO27824 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T870])

HSP 1 Score: 70.0922 bits (170), Expect = 1.716e-14
Identity = 52/142 (36.62%), Postives = 63/142 (44.37%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRC-IHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            N    C + +TCC    G   CC   NAVCC D  HCCP G  CD  +  C + +   PM         HA       TV+R+ + E          C DG  C    TCCL+    YGCCP    VCC D + CCP+G  C
Sbjct:   10 NDGSHCYDYETCCELSTGSYGCCPLPNAVCCSDGKHCCPCGYHCDISSSTCDMAKDSTPMV------SYHA-------TVQRAGVGEIK--------CKDGSHCNTGETCCLVGPTKYGCCPLPSAVCCADMQHCCPSGYTC 130

HSP 2 Score: 67.781 bits (164), Expect = 1.297e-13
Identity = 48/159 (30.19%), Postives = 65/159 (40.88%), Query Frame = 2

Query:  206 ITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            ++         V E  CK+ +  C   +TCC+    K  CC   +AVCC DM HCCP G TC+ K+  C  + +  +        +H   A+ K  V       +    G    C     C  Y TCC  ++    CCP     CC D   CCP G  C
Sbjct:   70 VSYHATVQRAGVGEIKCKDGSH-CNTGETCCLVGPTKYGCCPLPSAVCCADMQHCCPSGYTCNDKSGHC-QRGRHVLPMFQKHPSVHPRPAVAKTPVIIDHTIRFVPRGGRGAGC----ACEPYHTCCGSSSAQQNCCPLPNASCCSDGLHCCPQGFIC 222

HSP 3 Score: 46.9802 bits (110), Expect = 1.997e-6
Identity = 24/46 (52.17%), Postives = 26/46 (56.52%), Query Frame = 2

Query:  545 VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             C DG  C  Y TCC L+ G YGCCP    VCC D + CCP G  C
Sbjct:    8 TCNDGSHCYDYETCCELSTGSYGCCPLPNAVCCSDGKHCCPCGYHC 53

[Close]

BLAST of Granulin b vs. Ensembl Medaka
Match: grnb (granulin precursor [Source:NCBI gene;Acc:101166910])

HSP 1 Score: 90.8929 bits (224), Expect = 1.826e-20
Identity = 54/144 (37.50%), Postives = 68/144 (47.22%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +    C ++ TCC    G   CC +  AVCCED  HCCPEGTTCD  + +C   S +             ++ +P   V   P+     S+    VCP G   C    TCCLLT+G +GCCPY    CC D   CCP    C
Sbjct:   51 CPDQESECPDETTCCQLPDGSWGCCPFPKAVCCEDQRHCCPEGTTCDLVHSKCASPSLQ---------AFPMLQKVPAQRVGTLPVFAAAASV----VCPGGKSSCPNSFTCCLLTSGDFGCCPYPQATCCSDHLHCCPGNTTC 181

HSP 2 Score: 78.1814 bits (191), Expect = 3.659e-16
Identity = 50/143 (34.97%), Postives = 62/143 (43.36%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C +   +C +  TCC    G   CC   NAVCC D  HCCPEGTTCD  +  C+  +    E  +       +   P  T    P+R           C DG       TCC  + G +GCCP    VCC D   CCP+G  C
Sbjct:  210 CPDQRSMCPDGTTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMV-----PVSGTPPKT---HPVRGLAVPCNASVACADGS------TCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVC 338

HSP 3 Score: 76.2554 bits (186), Expect = 1.990e-15
Identity = 58/182 (31.87%), Postives = 73/182 (40.11%), Query Frame = 2

Query:  137 EVFLMKCPSLFLCALFLCIFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            ++   KC S  L A  +   V       +  F       C      C    TCC+   G   CC Y  A CC D  HCCP  TTCD +   C  +S E        + I A+ A P+  +              +++CPDG       TCC L NG +GCCP    VCC D   CCP G  C
Sbjct:   97 DLVHSKCASPSLQAFPMLQKVPAQRVGTLPVFAAAASVVCPGGKSSCPNSFTCCLLTSGDFGCCPYPQATCCSDHLHCCPGNTTCDLERGVC--KSGE-----ARVEPIRAVSASPEDVL----------CPDQRSMCPDG------TTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTC 255

HSP 4 Score: 71.633 bits (174), Expect = 6.055e-14
Identity = 50/153 (32.68%), Postives = 65/153 (42.48%), Query Frame = 2

Query:  230 FKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS--KEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            F    E+G  + +  C  + TCC T+ G   CC    AVCC+D  HCCP  T C+ + + C   S    P+ W     ++ A                  E  G   VCP      G  TCC  ++G + CCP    VCC D   CCP G KC
Sbjct:  363 FPYRSENGRCDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPLPWLTKRPRLTAGME--------------EEKCGKDAVCP------GRTTCCKNSSGQWACCPLPQAVCCSDLDHCCPKGYKC 495

HSP 5 Score: 66.2402 bits (160), Expect = 4.617e-12
Identity = 44/151 (29.14%), Postives = 66/151 (43.71%), Query Frame = 2

Query:  239 VDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNG-HYGCCPYSFGVCCPDKRTCCPNGRKCIP 688
            ++E+ C   + +C  + TCC    G+  CC    AVCC D+ HCCP+G  C+  ++ C       + W         + A+ + + +  P         ++N C     C    TCC +     +GCCP    VCC D   CCP G  C P
Sbjct:  446 MEEEKC-GKDAVCPGRTTCCKNSSGQWACCPLPQAVCCSDLDHCCPKGYKCNAFDRTCERPGGPSLPWR------QKLPALQQRSGQTGP---------VENKCDAQTSCPKDTTCCFMEQTLKWGCCPLPQAVCCGDGNHCCPRGHSCQP 580

HSP 6 Score: 65.855 bits (159), Expect = 5.309e-12
Identity = 45/141 (31.91%), Postives = 56/141 (39.72%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            N++  C +  TCC    G+  CC    AVCCED  HCCP GT C+     C   S   +   +S+         P +       R           C +   C G  TCC    G + CCP    VCC D   CCPN   C
Sbjct:  295 NASVACADGSTCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSN--------TPGFPYRSENGR-----------CDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATIC 416

HSP 7 Score: 59.3066 bits (142), Expect = 8.726e-10
Identity = 47/167 (28.14%), Postives = 69/167 (41.32%), Query Frame = 2

Query:  191 IFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG---KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +  +      +T    V +  C N +  C    TCC  + G   CC    AVCC D  HCCP+  TC+ +   C  ++ + +  +        + A P+ T               ++V  DG    KC    TCC ++   +GCCP    VCC D + CCP G  C
Sbjct:  591 VVPWFTKVGALTEPSGVTDVKCDNKSS-CASGTTCCPLQTGGWGCCPLVKAVCCADHEHCCPQSYTCNMQTGTCEKKAGQGLPLS------RVVPAQPQDT---------------QDVPCDGTGEFKCPKQNTCCRISATAWGCCPSPGAVCCMDSKHCCPAGYSC 735

HSP 8 Score: 58.151 bits (139), Expect = 2.408e-9
Identity = 45/143 (31.47%), Postives = 58/143 (40.56%), Query Frame = 2

Query:  260 NSNKICGEQKTCC-MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNV-CPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            ++   C +  TCC M +  K  CC    AVCC D +HCCP G +C      C   S                  +P +T     +    E  G+ +V C +   C    TCC L  G +GCCP    VCC D   CCP    C
Sbjct:  534 DAQTSCPKDTTCCFMEQTLKWGCCPLPQAVCCGDGNHCCPRGHSCQPHRSSCSRGS----------------HVVPWFTK----VGALTEPSGVTDVKCDNKSSCASGTTCCPLQTGGWGCCPLVKAVCCADHEHCCPQSYTC 656

[Close]

BLAST of Granulin b vs. Ensembl Medaka
Match: grna (granulins [Source:NCBI gene;Acc:101162601])

HSP 1 Score: 75.0998 bits (183), Expect = 4.848e-15
Identity = 48/153 (31.37%), Postives = 67/153 (43.79%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             +   V  D C N  K C + +TCC +      CC +  A CC D  HCCP+   CD     C + +   M W      +  + A  +   +   +   Y      N+CPD  +C    + CL     YGCCP + GV CPD + CCP G +C
Sbjct:   10 VSLALVAADMCPNGGK-CEKGQTCCQSPSKDYDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLS-MRW------VERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCPAEFS-CLKALTRYGCCPLAQGVSCPDGKHCCPEGHQC 153

HSP 2 Score: 74.7146 bits (182), Expect = 6.305e-15
Identity = 53/171 (30.99%), Postives = 73/171 (42.69%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS---------------------KEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKN-------VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            CK+    C ++ TCC  + GK  CC    AVCC+D  HCCPE TTCD +  +C+  S                     KE  E +    + +  K  P+ T   +P+  + E   +          C +   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  171 CKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTT-ANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 340

HSP 3 Score: 73.9442 bits (180), Expect = 1.193e-14
Identity = 47/142 (33.10%), Postives = 66/142 (46.48%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            N    C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  297 NETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------KVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 419

HSP 4 Score: 73.1738 bits (178), Expect = 1.943e-14
Identity = 51/158 (32.28%), Postives = 74/158 (46.84%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F +V    ED   + +  C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  360 VPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------NVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 498

HSP 5 Score: 72.7886 bits (177), Expect = 2.574e-14
Identity = 51/158 (32.28%), Postives = 73/158 (46.20%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F  V    ED   + +  C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  439 VPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------NVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 577

HSP 6 Score: 72.7886 bits (177), Expect = 2.574e-14
Identity = 51/158 (32.28%), Postives = 73/158 (46.20%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F  V    ED   + +  C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  518 VPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------NVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 656

HSP 7 Score: 72.4034 bits (176), Expect = 3.540e-14
Identity = 51/158 (32.28%), Postives = 72/158 (45.57%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F  V    ED   + +  C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC   +G +GCCP    VCC D   CCP G  C
Sbjct:  597 VPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------KVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTC 735

HSP 8 Score: 70.8626 bits (172), Expect = 1.184e-13
Identity = 52/143 (36.36%), Postives = 68/143 (47.55%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIP-GSCI 700
            C E  +CC    G+  CC   NAVCC D  HCCPEG TCD  +K C       +E TV    +     +P    +  P++       + N C D   C    TCC  ++  +GCC     VCC D + CCP+G +C   GSCI
Sbjct:  891 CPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGYTCDLASKSCHKLLTLQLE-TVPLTPVF----LPDDQSQHGPVKP------ILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCTKGGSCI 1022

HSP 9 Score: 66.2402 bits (160), Expect = 4.510e-12
Identity = 51/162 (31.48%), Postives = 70/162 (43.21%), Query Frame = 2

Query:  215 DGVTTFKQ---VDEDGCK--NSNKICGEQKTCC-MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            DG   F +    DE+G    +S+  C +  TCC M ++ K  CC    AVCC D  HCCP    C  ++  C+                     IP YT  + P  +  ++      C    +C  +++CC L  G +GCCP    VCC DK  CCP G  C
Sbjct:  786 DGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKGEV----------------VIPWYT--KIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGYTC 929

HSP 10 Score: 65.4698 bits (158), Expect = 8.814e-12
Identity = 57/175 (32.57%), Postives = 74/175 (42.29%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSK-EPM--EWTVSDDKIHAIKAIPKYTVE------RSPLREWYESIGLKN--------VCPDGGKCTGYLTCCLLTNGH-YGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F +V    ED   + +  C +Q TCC TK G   CC    AVCC+D  HCCP GTTCD     C+  S   PM  +   S     A   + K   E      +   R+  E    ++         C    +C  + TCC +     +GCCP    VCC D   CCP   KC
Sbjct:  676 VPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKC 850

HSP 11 Score: 51.6026 bits (122), Expect = 3.110e-7
Identity = 42/158 (26.58%), Postives = 60/158 (37.97%), Query Frame = 2

Query:  227 TFKQVDEDGCKNSNKICGEQKTC-----CMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +F+ +     ++ + IC +Q  C     C+  + +  CC     V C D  HCCPEG  C   ++ C+              K  +IK +                     +C DG  +C    TCC    G + CCP    VCC DK  CCP    C
Sbjct:   94 SFRMIRSYMGEDEDNICPDQSRCPAEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSCV--------------KKESIKTV---------------------LCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTC 216

[Close]

BLAST of Granulin b vs. Ensembl Medaka
Match: grna (granulins [Source:NCBI gene;Acc:101162601])

HSP 1 Score: 75.0998 bits (183), Expect = 5.150e-15
Identity = 48/153 (31.37%), Postives = 67/153 (43.79%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             +   V  D C N  K C + +TCC +      CC +  A CC D  HCCP+   CD     C + +   M W      +  + A  +   +   +   Y      N+CPD  +C    + CL     YGCCP + GV CPD + CCP G +C
Sbjct:   10 VSLALVAADMCPNGGK-CEKGQTCCQSPSKDYDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLS-MRW------VERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCPAEFS-CLKALTRYGCCPLAQGVSCPDGKHCCPEGHQC 153

HSP 2 Score: 74.7146 bits (182), Expect = 6.098e-15
Identity = 53/171 (30.99%), Postives = 73/171 (42.69%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS---------------------KEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKN-------VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            CK+    C ++ TCC  + GK  CC    AVCC+D  HCCPE TTCD +  +C+  S                     KE  E +    + +  K  P+ T   +P+  + E   +          C +   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  171 CKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTT-ANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 340

HSP 3 Score: 73.9442 bits (180), Expect = 1.221e-14
Identity = 47/142 (33.10%), Postives = 66/142 (46.48%), Query Frame = 2

Query:  260 NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            N    C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  297 NETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------KVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 419

HSP 4 Score: 73.1738 bits (178), Expect = 2.007e-14
Identity = 51/158 (32.28%), Postives = 74/158 (46.84%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F +V    ED   + +  C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  360 VPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------NVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 498

HSP 5 Score: 73.1738 bits (178), Expect = 2.007e-14
Identity = 51/158 (32.28%), Postives = 74/158 (46.84%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F +V    ED   + +  C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  597 VPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------NVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 735

HSP 6 Score: 72.7886 bits (177), Expect = 2.658e-14
Identity = 51/158 (32.28%), Postives = 73/158 (46.20%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F  V    ED   + +  C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  439 VPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------NVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 577

HSP 7 Score: 72.7886 bits (177), Expect = 2.658e-14
Identity = 51/158 (32.28%), Postives = 73/158 (46.20%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F  V    ED   + +  C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC    G +GCCP+   VCC D   CCP G+ C
Sbjct:  518 VPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------KVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTC 656

HSP 8 Score: 72.4034 bits (176), Expect = 3.655e-14
Identity = 51/158 (32.28%), Postives = 72/158 (45.57%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F  V    ED   + +  C +Q TCC T+ G   CC +  AVCCED  HCCP+G TC+   + C                +  ++ +P ++           S+ +++V  DG   C    TCC   +G +GCCP    VCC D   CCP G  C
Sbjct:  676 VPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGG----------SVPMLEKVPSFS---------KVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTC 814

HSP 9 Score: 70.8626 bits (172), Expect = 1.293e-13
Identity = 52/143 (36.36%), Postives = 68/143 (47.55%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIP-GSCI 700
            C E  +CC    G+  CC   NAVCC D  HCCPEG TCD  +K C       +E TV    +     +P    +  P++       + N C D   C    TCC  ++  +GCC     VCC D + CCP+G +C   GSCI
Sbjct:  970 CPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGYTCDLASKSCHKLLTLQLE-TVPLTPVF----LPDDQSQHGPVKP------ILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCTKGGSCI 1101

HSP 10 Score: 66.2402 bits (160), Expect = 4.922e-12
Identity = 51/162 (31.48%), Postives = 70/162 (43.21%), Query Frame = 2

Query:  215 DGVTTFKQ---VDEDGCK--NSNKICGEQKTCC-MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            DG   F +    DE+G    +S+  C +  TCC M ++ K  CC    AVCC D  HCCP    C  ++  C+                     IP YT  + P  +  ++      C    +C  +++CC L  G +GCCP    VCC DK  CCP G  C
Sbjct:  865 DGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKGEV----------------VIPWYT--KIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGYTC 1008

HSP 11 Score: 65.4698 bits (158), Expect = 9.012e-12
Identity = 57/175 (32.57%), Postives = 74/175 (42.29%), Query Frame = 2

Query:  221 VTTFKQVD---EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSK-EPM--EWTVSDDKIHAIKAIPKYTVE------RSPLREWYESIGLKN--------VCPDGGKCTGYLTCCLLTNGH-YGCCPYSFGVCCPDKRTCCPNGRKC 682
            V +F +V    ED   + +  C +Q TCC TK G   CC    AVCC+D  HCCP GTTCD     C+  S   PM  +   S     A   + K   E      +   R+  E    ++         C    +C  + TCC +     +GCCP    VCC D   CCP   KC
Sbjct:  755 VPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKC 929

HSP 12 Score: 51.6026 bits (122), Expect = 3.322e-7
Identity = 42/158 (26.58%), Postives = 60/158 (37.97%), Query Frame = 2

Query:  227 TFKQVDEDGCKNSNKICGEQKTC-----CMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            +F+ +     ++ + IC +Q  C     C+  + +  CC     V C D  HCCPEG  C   ++ C+              K  +IK +                     +C DG  +C    TCC    G + CCP    VCC DK  CCP    C
Sbjct:   94 SFRMIRSYMGEDEDNICPDQSRCPAEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSCV--------------KKESIKTV---------------------LCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTC 216

[Close]

BLAST of Granulin b vs. Ensembl Medaka
Match: ENSORLT00000005071.2 (granulins [Source:NCBI gene;Acc:101168633])

HSP 1 Score: 61.2326 bits (147), Expect = 1.176e-10
Identity = 47/145 (32.41%), Postives = 59/145 (40.69%), Query Frame = 2

Query:  266 NKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEW-TVSDDKIHAIKAIPKYTVERSPLREWYESIGLKN-----VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             K+C +  TCC+T  G   CC    AVCC D +HCCP G  C+     C    K    W ++      A +  P   +  + + E     GL        C     C    TCC    G + CCPY  G CC D   CCP G  C
Sbjct:   29 GKLCPDLSTCCLTGHGF-SCCPLPEAVCCSDKAHCCPSGYRCNLATMMC---EKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDC 169

HSP 2 Score: 58.5362 bits (140), Expect = 8.975e-10
Identity = 52/183 (28.42%), Postives = 69/183 (37.70%), Query Frame = 2

Query:  197 VYDITTDGVTTFKQVDEDGCK------NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS-KEPMEWTVS-------------DDKIHAIKAIPKYT-VERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
              D++T+ V   K  +    K      +S  +C ++ TCC    G   CC Y    CC D  HCCP G  CD     CI    K P  +  +             ++ I   K++   T    +P          K  CP G       +CC    G + CCPY  G CC D R CC  G  C
Sbjct:   99 ALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAG------TSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTC 275

[Close]

BLAST of Granulin b vs. Ensembl Medaka
Match: ENSORLT00000029765.1 (granulins [Source:NCBI gene;Acc:101168633])

HSP 1 Score: 60.8474 bits (146), Expect = 1.224e-10
Identity = 47/145 (32.41%), Postives = 59/145 (40.69%), Query Frame = 2

Query:  266 NKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEW-TVSDDKIHAIKAIPKYTVERSPLREWYESIGLKN-----VCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
             K+C +  TCC+T  G   CC    AVCC D +HCCP G  C+     C    K    W ++      A +  P   +  + + E     GL        C     C    TCC    G + CCPY  G CC D   CCP G  C
Sbjct:   27 GKLCPDLSTCCLTGHGF-SCCPLPEAVCCSDKAHCCPSGYRCNLATMMC---EKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDC 167

HSP 2 Score: 58.5362 bits (140), Expect = 9.034e-10
Identity = 52/183 (28.42%), Postives = 69/183 (37.70%), Query Frame = 2

Query:  197 VYDITTDGVTTFKQVDEDGCK------NSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQS-KEPMEWTVS-------------DDKIHAIKAIPKYT-VERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
              D++T+ V   K  +    K      +S  +C ++ TCC    G   CC Y    CC D  HCCP G  CD     CI    K P  +  +             ++ I   K++   T    +P          K  CP G       +CC    G + CCPY  G CC D R CC  G  C
Sbjct:   97 ALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAG------TSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTC 273

[Close]

BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000002628.1 (SMESG000002628.1)

HSP 1 Score: 274.248 bits (700), Expect = 1.096e-94
Identity = 134/134 (100.00%), Postives = 134/134 (100.00%), Query Frame = 2

Query:  299 MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 700
            MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI
Sbjct:    1 MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI 134

[Close]

BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018770.1 (SMESG000018770.1)

HSP 1 Score: 112.849 bits (281), Expect = 1.313e-28
Identity = 65/179 (36.31%), Postives = 88/179 (49.16%), Query Frame = 2

Query:  179 LFLCIFVYDITTDGVTTFKQVDEDG--------CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDK--IHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            + L I V    TDG+ +F +  +D         C N+   C E +TCC+TK     CC+Y NA+CC D  HCCP G+TCD   KRC    + PMEW V ++   +  +   P  T+           +     CP+   KC    TCC+  +G+Y CCP+   VCC DK  CCP   KC
Sbjct:    1 MILTIIVDYALTDGIFSFNKASQDQVSEKNENVCPNNRTKCKETQTCCVTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKC 179

HSP 2 Score: 98.2117 bits (243), Expect = 1.958e-23
Identity = 59/153 (38.56%), Postives = 81/153 (52.94%), Query Frame = 2

Query:  227 TFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGK-CTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            T +  D+  C N+   C + KTCC+TK G   CC + NAVCC D  +CCPE T CD KNK+C+  S        +  K   +K+   YT              L+  CP+  K C G   CC ++ GH+GCC ++ G+CCPD +TCCP+   C
Sbjct:  125 TLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKCLDSS-----AVFNSYKNPGLKSANLYT-----FYSLLNVDKLEKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDC 267

HSP 3 Score: 96.6709 bits (239), Expect = 8.945e-23
Identity = 55/141 (39.01%), Postives = 72/141 (51.06%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSC 697
            C   +TCC    G   CC + NA CC D + CCP    CD + K C  ++KE  + +++  K                L  +Y  IGLK +CPD  KC     CC + +  YGCC Y  GVCC DK+TCCPNG +C+ G C
Sbjct:  307 CQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVCDLEKKVC--KNKETSQPSITKSK---------------SLLHFYSEIGLKVICPDQTKCENDSVCCQMDDNQYGCCSYKNGVCCADKQTCCPNGTQCVSGGC 430

HSP 4 Score: 85.1149 bits (209), Expect = 8.795e-19
Identity = 54/147 (36.73%), Postives = 71/147 (48.30%), Query Frame = 2

Query:  245 EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            E  C NS K C  QK CC    G   CC++   +CC DM  CCP  T CD+  K C+ +S +  E             IP    E  P  +    I L N+CPD   +C  + TCC + +G YGCCP+    CC D  +CCP+ + C
Sbjct:  219 EKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDCDSAKKACVSKSSDLTE-------------IPN---ELQPEAQ----IKLNNICPDKHVECQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVC 345

[Close]

BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018770.1 (SMESG000018770.1)

HSP 1 Score: 112.464 bits (280), Expect = 1.514e-28
Identity = 65/179 (36.31%), Postives = 88/179 (49.16%), Query Frame = 2

Query:  179 LFLCIFVYDITTDGVTTFKQVDEDG--------CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDK--IHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            + L I V    TDG+ +F +  +D         C N+   C E +TCC+TK     CC+Y NA+CC D  HCCP G+TCD   KRC    + PMEW V ++   +  +   P  T+           +     CP+   KC    TCC+  +G+Y CCP+   VCC DK  CCP   KC
Sbjct:   10 MILTIIVDYALTDGIFSFNKASQDQVSEKNENVCPNNRTKCKETQTCCVTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKC 188

HSP 2 Score: 98.5969 bits (244), Expect = 1.906e-23
Identity = 59/153 (38.56%), Postives = 81/153 (52.94%), Query Frame = 2

Query:  227 TFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGK-CTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            T +  D+  C N+   C + KTCC+TK G   CC + NAVCC D  +CCPE T CD KNK+C+  S        +  K   +K+   YT              L+  CP+  K C G   CC ++ GH+GCC ++ G+CCPD +TCCP+   C
Sbjct:  134 TLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKCLDSS-----AVFNSYKNPGLKSANLYT-----FYSLLNVDKLEKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDC 276

HSP 3 Score: 96.6709 bits (239), Expect = 8.673e-23
Identity = 55/141 (39.01%), Postives = 72/141 (51.06%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSC 697
            C   +TCC    G   CC + NA CC D + CCP    CD + K C  ++KE  + +++  K                L  +Y  IGLK +CPD  KC     CC + +  YGCC Y  GVCC DK+TCCPNG +C+ G C
Sbjct:  316 CQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVCDLEKKVC--KNKETSQPSITKSK---------------SLLHFYSEIGLKVICPDQTKCENDSVCCQMDDNQYGCCSYKNGVCCADKQTCCPNGTQCVSGGC 439

HSP 4 Score: 85.1149 bits (209), Expect = 8.434e-19
Identity = 54/147 (36.73%), Postives = 71/147 (48.30%), Query Frame = 2

Query:  245 EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            E  C NS K C  QK CC    G   CC++   +CC DM  CCP  T CD+  K C+ +S +  E             IP    E  P  +    I L N+CPD   +C  + TCC + +G YGCCP+    CC D  +CCP+ + C
Sbjct:  228 EKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDCDSAKKACVSKSSDLTE-------------IPN---ELQPEAQ----IKLNNICPDKHVECQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVC 354

[Close]

BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018770.1 (SMESG000018770.1)

HSP 1 Score: 112.464 bits (280), Expect = 1.675e-28
Identity = 65/179 (36.31%), Postives = 88/179 (49.16%), Query Frame = 2

Query:  179 LFLCIFVYDITTDGVTTFKQVDEDG--------CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDK--IHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            + L I V    TDG+ +F +  +D         C N+   C E +TCC+TK     CC+Y NA+CC D  HCCP G+TCD   KRC    + PMEW V ++   +  +   P  T+           +     CP+   KC    TCC+  +G+Y CCP+   VCC DK  CCP   KC
Sbjct:    7 MILTIIVDYALTDGIFSFNKASQDQVSEKNENVCPNNRTKCKETQTCCVTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKC 185

HSP 2 Score: 98.2117 bits (243), Expect = 2.209e-23
Identity = 59/153 (38.56%), Postives = 81/153 (52.94%), Query Frame = 2

Query:  227 TFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGK-CTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            T +  D+  C N+   C + KTCC+TK G   CC + NAVCC D  +CCPE T CD KNK+C+  S        +  K   +K+   YT              L+  CP+  K C G   CC ++ GH+GCC ++ G+CCPD +TCCP+   C
Sbjct:  131 TLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKCLDSS-----AVFNSYKNPGLKSANLYT-----FYSLLNVDKLEKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDC 273

HSP 3 Score: 96.2857 bits (238), Expect = 1.016e-22
Identity = 55/141 (39.01%), Postives = 72/141 (51.06%), Query Frame = 2

Query:  275 CGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSC 697
            C   +TCC    G   CC + NA CC D + CCP    CD + K C  ++KE  + +++  K                L  +Y  IGLK +CPD  KC     CC + +  YGCC Y  GVCC DK+TCCPNG +C+ G C
Sbjct:  313 CQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVCDLEKKVC--KNKETSQPSITKSK---------------SLLHFYSEIGLKVICPDQTKCENDSVCCQMDDNQYGCCSYKNGVCCADKQTCCPNGTQCVSGGC 436

HSP 4 Score: 85.1149 bits (209), Expect = 9.543e-19
Identity = 54/147 (36.73%), Postives = 71/147 (48.30%), Query Frame = 2

Query:  245 EDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            E  C NS K C  QK CC    G   CC++   +CC DM  CCP  T CD+  K C+ +S +  E             IP    E  P  +    I L N+CPD   +C  + TCC + +G YGCCP+    CC D  +CCP+ + C
Sbjct:  225 EKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDCDSAKKACVSKSSDLTE-------------IPN---ELQPEAQ----IKLNNICPDKHVECQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVC 351

[Close]

BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018760.1 (SMESG000018760.1)

HSP 1 Score: 105.145 bits (261), Expect = 1.913e-25
Identity = 64/163 (39.26%), Postives = 83/163 (50.92%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESI---------GLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            T  K + +  C N+   C + +TCC+TK G   CC++ NAVCC D  HCCPEG+TCD K  +C+  +K  +E           K IP   VE  P     E+           + N+CP+   KCT   TCC   +  Y CC Y+  VCCPDK  CCPNG  C
Sbjct:   95 TDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMR---------KLIPALKVEDEPKTNILEAKVNEKDENKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSC 248

HSP 2 Score: 94.7449 bits (234), Expect = 6.961e-22
Identity = 59/157 (37.58%), Postives = 81/157 (51.59%), Query Frame = 2

Query:  224 TTFKQVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYES-IGLKN--VCPDGG-KCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            T  K + +  C N+   C + +TCC+TK G   CC++ NAVCC D  HCCPEG+TCD K  +C+  +K  +E           K IP   VE        E+ +  K+  +CP+   KC    TCC+  + +Y CCP+   VCC DK  CCP    C
Sbjct:  281 TDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMG---------KLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTC 428

HSP 3 Score: 92.4337 bits (228), Expect = 4.080e-21
Identity = 57/147 (38.78%), Postives = 74/147 (50.34%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRC---IHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C N    C E++TCC TK     CC+Y NAVCC D  HCCP GT+CD+ +K+C   I  +K P++ T                +E   + E    I     CP+   KC    TCC+  +G Y CC ++  VCCPDK  CCP G  C
Sbjct:   17 CPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPE-------------PMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTC 150

HSP 4 Score: 92.4337 bits (228), Expect = 4.080e-21
Identity = 57/147 (38.78%), Postives = 74/147 (50.34%), Query Frame = 2

Query:  254 CKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRC---IHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            C N    C E++TCC TK     CC+Y NAVCC D  HCCP GT+CD+ +K+C   I  +K P++ T                +E   + E    I     CP+   KC    TCC+  +G Y CC ++  VCCPDK  CCP G  C
Sbjct:  203 CPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPE-------------PMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTC 336

HSP 5 Score: 82.8037 bits (203), Expect = 7.124e-18
Identity = 57/151 (37.75%), Postives = 73/151 (48.34%), Query Frame = 2

Query:  236 QVDEDGCKNSNKICGEQKTCCMTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIH--QSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            + DE  C N+   C + KTCC+TK     CC + NAVCC D   CCPE TTCD KNK+C     S   +   ++ + IH       +  E +  +     +G K       K   Y   C +TNG  G C +S G CC D RTCCP   KC
Sbjct:  377 EKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHD-----SFKYETNFFKIISLLLGFKQ---KASKSDFY---CPITNGRSGRCKFSAGTCCSDLRTCCPQHTKC 516

HSP 6 Score: 61.6178 bits (148), Expect = 1.164e-10
Identity = 39/125 (31.20%), Postives = 59/125 (47.20%), Query Frame = 2

Query:  311 GKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTVSDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDG-GKCTGYLTCCLLTNGHYGCCPYSFGVCCPDKRTCCPNGRKC 682
            G+   C+++   CC D+  CCP+ T CD KN +C   S    ++     K              SP      ++    VCPD   +C  + TCC +++  YGCC     VCC D+ +CCP+ +KC
Sbjct:  490 GRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNS---TDFDTEKSK-------------HSPNTNRLSTV----VCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKC 594

The following BLAST results are available for this feature:

BLAST of Granulin b vs. Ensembl Human
BLAST of Granulin b vs. Ensembl Celegans
BLAST of Granulin b vs. Ensembl Fly
BLAST of Granulin b vs. Ensembl Zebrafish
BLAST of Granulin b vs. Ensembl Xenopus
BLAST of Granulin b vs. Ensembl Mouse
BLAST of Granulin b vs. UniProt/SwissProt
BLAST of Granulin b vs. TrEMBL
BLAST of Granulin b vs. Ensembl Cavefish
BLAST of Granulin b vs. Ensembl Sea Lamprey
BLAST of Granulin b vs. Ensembl Yeast
BLAST of Granulin b vs. Ensembl Nematostella
BLAST of Granulin b vs. Ensembl Medaka
BLAST of Granulin b vs. Planmine SMEST

BLAST of Granulin b vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
GRN	2.244e-17	33.15	granulin precursor [Source:HGNC Symbol;Acc:HGNC:46...	[more]
GRN	3.265e-17	33.15	granulin precursor [Source:HGNC Symbol;Acc:HGNC:46...	[more]
GRN	6.527e-17	36.36	granulin precursor [Source:HGNC Symbol;Acc:HGNC:46...	[more]
GRN	3.992e-16	32.61	granulin precursor [Source:HGNC Symbol;Acc:HGNC:46...	[more]
GRN	4.996e-10	32.77	granulin precursor [Source:HGNC Symbol;Acc:HGNC:46...	[more]

BLAST of Granulin b vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
pgrn-1	2.187e-22	38.71	ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:...	[more]
pgrn-1	3.069e-22	38.71	ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:...	[more]

BLAST of Granulin b vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Granulin b vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
grnb	2.525e-18	37.24	granulin b [Source:ZFIN;Acc:ZDB-GENE-030131-7393]	[more]
grna	4.492e-17	37.06	granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]	[more]
grna	1.871e-16	32.90	granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]	[more]
grna	8.877e-16	35.17	granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]	[more]
grna	9.283e-16	35.17	granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]	[more]

BLAST of Granulin b vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
trappc11	5.318e-15	36.11	trafficking protein particle complex 11 [Source:Xe...	[more]
trappc11	6.874e-15	36.11	trafficking protein particle complex 11 [Source:Xe...	[more]
trappc11	1.257e-12	34.01	trafficking protein particle complex 11 [Source:Xe...	[more]
trappc11	1.430e-12	33.56	trafficking protein particle complex 11 [Source:Xe...	[more]

BLAST of Granulin b vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Grn	2.100e-15	33.53	granulin [Source:MGI Symbol;Acc:MGI:95832]	[more]
Grn	2.309e-14	35.71	granulin [Source:MGI Symbol;Acc:MGI:95832]	[more]
Grn	2.296e-11	28.28	granulin [Source:MGI Symbol;Acc:MGI:95832]	[more]
Grn	4.713e-8	30.88	granulin [Source:MGI Symbol;Acc:MGI:95832]	[more]

BLAST of Granulin b vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P28797\|GRN_CAVPO	4.500e-17	32.08	Progranulin OS=Cavia porcellus OX=10141 GN=GRN PE=...	[more]
sp\|P28799\|GRN_HUMAN	1.568e-16	33.15	Progranulin OS=Homo sapiens OX=9606 GN=GRN PE=1 SV...	[more]
sp\|P23785\|GRN_RAT	5.857e-16	33.74	Progranulin OS=Rattus norvegicus OX=10116 GN=Grn P...	[more]
sp\|P28798\|GRN_MOUSE	1.376e-14	33.53	Progranulin OS=Mus musculus OX=10090 GN=Grn PE=1 S...	[more]
sp\|P80059\|PMD1_LOCMI	2.361e-7	48.08	Pars intercerebralis major peptide D1 OS=Locusta m...	[more]

BLAST of Granulin b vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A023GCS2	3.032e-21	34.32	Putative granulin (Fragment) OS=Amblyomma triste O...	[more]
A0A226F5G2	3.947e-20	32.20	Granulins OS=Folsomia candida OX=158441 GN=Fcan01_...	[more]
A0A131XWJ6	4.116e-20	37.14	Putative granulin (Fragment) OS=Ixodes ricinus OX=...	[more]
A0A443S242	9.329e-20	41.67	Uncharacterized protein OS=Leptotrombidium deliens...	[more]
A0A0B2W2D5	2.917e-19	39.19	Granulin (Fragment) OS=Toxocara canis OX=6265 GN=G...	[more]

BLAST of Granulin b vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
grnb	3.501e-17	37.68	granulins-like [Source:NCBI gene;Acc:103046308]	[more]
grnb	3.501e-17	37.68	granulins-like [Source:NCBI gene;Acc:103046308]	[more]
ENSAMXT00000034465.1	3.584e-15	32.88	pep primary_assembly:Astyanax_mexicanus-2.0:23:267...	[more]
ENSAMXT00000030959.1	3.584e-15	32.88	pep primary_assembly:Astyanax_mexicanus-2.0:23:267...	[more]
ENSAMXT00000057729.1	3.584e-15	32.88	pep primary_assembly:Astyanax_mexicanus-2.0:23:267...	[more]

BLAST of Granulin b vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000009302.1	9.873e-17	36.76	pep scaffold:Pmarinus_7.0:GL483232:1183:11161:1 ge...	[more]
ENSPMAT00000001039.1	3.922e-9	27.89	pep scaffold:Pmarinus_7.0:GL484091:11570:24665:-1 ...	[more]

BLAST of Granulin b vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Granulin b vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO27824	1.716e-14	36.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Granulin b vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
grnb	1.826e-20	37.50	granulin precursor [Source:NCBI gene;Acc:101166910...	[more]
grna	4.848e-15	31.37	granulins [Source:NCBI gene;Acc:101162601]	[more]
grna	5.150e-15	31.37	granulins [Source:NCBI gene;Acc:101162601]	[more]
ENSORLT00000005071.2	1.176e-10	32.41	granulins [Source:NCBI gene;Acc:101168633]	[more]
ENSORLT00000029765.1	1.224e-10	32.41	granulins [Source:NCBI gene;Acc:101168633]	[more]

BLAST of Granulin b vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000002628.1	1.096e-94	100.00	SMESG000002628.1	[more]
SMESG000018770.1	1.313e-28	36.31	SMESG000018770.1	[more]
SMESG000018770.1	1.514e-28	36.31	SMESG000018770.1	[more]
SMESG000018770.1	1.675e-28	36.31	SMESG000018770.1	[more]
SMESG000018760.1	1.913e-25	39.26	SMESG000018760.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034503 ID=SMED30034503|Name=Granulin b|organism=Schmidtea mediterranea sexual|type=transcript|length=757bp
CAAAATACATTGATTATTTTGGCATCCGGATTGATACAGTTTAATCATAA
ACAAATGATGTTTAATCATAAACAAAATATTGTTTATTCTAATAATGGAG
TCTTTGTATAAATTAGTGAAAATAATATAATAATCAGAAGTTTTCCTAAT
GAAGTGTCCTAGTCTGTTTTTGTGTGCATTATTTTTATGTATTTTTGTCT
ATGATATAACTACTGATGGCGTTACGACATTCAAACAAGTAGATGAAGAT
GGGTGTAAAAATAGCAATAAGATATGTGGAGAACAAAAAACCTGTTGTAT
GACTAAAATTGGTAAACCCAAATGTTGCCAATATACTAATGCAGTCTGCT
GTGAGGATATGTCACATTGTTGTCCTGAAGGCACGACATGTGATACAAAA
AATAAAAGATGTATTCATCAATCTAAAGAACCAATGGAGTGGACTGTATC
GGACGACAAGATTCATGCAATAAAAGCAATTCCAAAATATACAGTGGAGA
GATCACCATTGAGAGAATGGTATGAGAGTATTGGATTGAAAAATGTTTGC
CCAGATGGAGGTAAATGTACAGGCTATCTGACTTGTTGCTTATTGACAAA
TGGACACTATGGATGTTGTCCATACAGTTTTGGAGTTTGTTGTCCCGACA
AACGAACATGTTGCCCAAATGGTCGAAAATGCATTCCTGGATCTTGCATT
TAATTTGAACTATATTAACGATTATTTCTTGATCAAATTGGCTTCATGAA
ATGTGAT

protein sequence of SMED30034503-orf-1

>SMED30034503-orf-1 ID=SMED30034503-orf-1|Name=SMED30034503-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=185bp
MKCPSLFLCALFLCIFVYDITTDGVTTFKQVDEDGCKNSNKICGEQKTCC
MTKIGKPKCCQYTNAVCCEDMSHCCPEGTTCDTKNKRCIHQSKEPMEWTV
SDDKIHAIKAIPKYTVERSPLREWYESIGLKNVCPDGGKCTGYLTCCLLT
NGHYGCCPYSFGVCCPDKRTCCPNGRKCIPGSCI*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0003116	parenchymal cell
PLANA:0007528	glial cell

Vocabulary: **INTERPRO**
Term	Definition
IPR037277	Granulin_sf
IPR039036	Granulin_fam
IPR000118	Granulin

Vocabulary: **molecular function**
Term	Definition
GO:0003723	RNA binding
GO:0005125	cytokine activity
GO:0005515	protein binding
GO:0008083	growth factor activity

Vocabulary: **cellular component**
Term	Definition
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005764	lysosome
GO:0005768	endosome
GO:0005783	endoplasmic reticulum
GO:0035578	azurophil granule lumen
GO:0070062	extracellular exosome

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction
GO:0043312	neutrophil degranulation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000118	Granulin	SMART	SM00277	GRAN_2	coord: 134..183 e-value: 7.4E-5 score: 31.5 coord: 36..88 e-value: 1.4E-13 score: 61.2
IPR000118	Granulin	PFAM	PF00396	Granulin	coord: 145..180 e-value: 2.5E-10 score: 40.5 coord: 48..89 e-value: 3.0E-13 score: 49.8
IPR000118	Granulin	PROSITE	PS00799	GRANULINS	coord: 68..81
IPR037277	Granulin superfamily	GENE3D	G3DSA:3.10.20.500		coord: 132..184 e-value: 2.3E-11 score: 45.6
IPR037277	Granulin superfamily	GENE3D	G3DSA:3.10.20.500		coord: 33..91 e-value: 1.1E-12 score: 50.0
IPR039036	Granulin family	PANTHER	PTHR12274	GRANULIN	coord: 25..100
IPR039036	Granulin family	PANTHER	PTHR12274	GRANULIN	coord: 132..178
None	No IPR available	PANTHER	PTHR12274:SF3	GRANULINS	coord: 132..178
None	No IPR available	PANTHER	PTHR12274:SF3	GRANULINS	coord: 25..100
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..22 score: 0.845
None	No IPR available	SUPERFAMILY	SSF57277	Granulin repeat	coord: 133..159

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Granulin b

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

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