FGFR1

Overview


Name	FGFR1 (AFD29628.1)
Smed ID	SMED30034490
Length (bp)	2276

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of FGFR1 (SMED30034490) t-SNE clustered cells

Violin plots show distribution of expression levels for FGFR1 (SMED30034490) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of FGFR1 (SMED30034490) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for FGFR1 (SMED30034490) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034490

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 26

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pigment cell	SMED30034490	SMESG000036598.1 SMESG000036590.1	SmedASXL_015337	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
X1 cell	SMED30034490	SMESG000036590.1	SmedASXL_015338	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30034490	SMESG000036598.1 SMESG000036590.1	SmedASXL_015337	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30034490	SMESG000036598.1 SMESG000036590.1	SmedASXL_015337	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
pharynx	SMED30034490	SMESG000036598.1 SMESG000036590.1	dd_Smed_v4_6020_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30034490	SMESG000036598.1 SMESG000036590.1	dd_Smed_v4_6020_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30034490	SMESG000036598.1 SMESG000036590.1	dd_Smed_v4_6020_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30034490	SMESG000036598.1 SMESG000036590.1	dd_Smed_v4_6020_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
zeta neoblast	SMED30034490	SMESG000036598.1 SMESG000036590.1	JQ425160	smed_ncbi_20200123	PMID:25017721 van Wolfswinkel et al., 2014
zeta neoblast	SMED30034490	SMESG000036598.1 SMESG000036590.1	JQ425160	smed_ncbi_20200123	PMID:25017721 van Wolfswinkel et al., 2014
parenchyma	SMED30034490	SMESG000036598.1 SMESG000036590.1	SMED30034490	smed_20140614	PMID:26457503 Tu et al., 2015
neoblast	SMED30034490	SMESG000036598.1 SMESG000036590.1	JQ425160.1	smed_ncbi_20200123	PMID:27523733 Lei et al., 2016
neoblast	SMED30034490	SMESG000036598.1 SMESG000036590.1	JQ425160.1	smed_ncbi_20200123	PMID:27523733 Lei et al., 2016
neoblast	SMED30034490	SMESG000036598.1	SMED_38140_V2_2	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036598.1	SMED_38140_V2_2	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036590.1	SMED_38141_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036590.1	SMED_38141_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036598.1	SMED_38140_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036598.1	SMED_38140_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036590.1	SMED_38141_V2_2	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036590.1	SMED_38141_V2_2	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036598.1	SMED_23395_V2_2	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036598.1	SMED_23395_V2_2	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036598.1	SMED_23395_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036598.1	SMED_23395_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034490	SMESG000036598.1 SMESG000036590.1	SMED30034490	smed_20140614	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of FGFR1 vs. Ensembl Human
Match: FGFR2 (fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689])

HSP 1 Score: 199.134 bits (505), Expect = 2.144e-54
Identity = 108/294 (36.73%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSV---------DSRDVAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL-------INH-PCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + K E PR+ + + G  LGEG FG V +            ++  VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YL++  P        IN  P +++    L + T Q+ +GM YL+S+  +HRDLA RN+L+ EN  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G+++WEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  240 LPEDPKWEFPRDKLTL-GKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 532

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BLAST of FGFR1 vs. Ensembl Human
Match: FGFR1 (fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688])

HSP 1 Score: 200.29 bits (508), Expect = 7.334e-54
Identity = 109/294 (37.07%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL--------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + + E+PR+ + V G  LGEG FG V L      D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YLQ+  P          ++P ++++   L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  376 LPEDPRWELPRDRL-VLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 668

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BLAST of FGFR1 vs. Ensembl Human
Match: FGFR1 (fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688])

HSP 1 Score: 200.29 bits (508), Expect = 7.477e-54
Identity = 109/294 (37.07%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL--------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + + E+PR+ + V G  LGEG FG V L      D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YLQ+  P          ++P ++++   L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  376 LPEDPRWELPRDRL-VLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 668

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BLAST of FGFR1 vs. Ensembl Human
Match: FGFR1 (fibroblast growth factor receptor 1 [Source:HGNC Symbol;Acc:HGNC:3688])

HSP 1 Score: 199.904 bits (507), Expect = 7.809e-54
Identity = 109/294 (37.07%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL--------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + + E+PR+ + V G  LGEG FG V L      D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YLQ+  P          ++P ++++   L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  374 LPEDPRWELPRDRL-VLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 666

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BLAST of FGFR1 vs. Ensembl Human
Match: FGFR2 (fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689])

HSP 1 Score: 199.134 bits (505), Expect = 9.992e-54
Identity = 108/294 (36.73%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSV---------DSRDVAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL-------INH-PCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + K E PR+ + + G  LGEG FG V +            ++  VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YL++  P        IN  P +++    L + T Q+ +GM YL+S+  +HRDLA RN+L+ EN  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G+++WEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  380 LPEDPKWEFPRDKLTL-GKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 672

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BLAST of FGFR1 vs. Ensembl Celegans
Match: R151.1 (pep chromosome:WBcel235:III:7218813:7221186:1 gene:WBGene00020106.1 transcript:R151.1c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:R151.1)

HSP 1 Score: 172.555 bits (436), Expect = 2.396e-46
Identity = 94/270 (34.81%), Postives = 153/270 (56.67%), Query Frame = 3

Query: 1377 RNHVKVSGVKLGEGNFGTVFLGSVDSRD-----VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            R    V G  +GEG FG VF G +   +     VA+K       ++ ++    E++MMQ +G+H +++ + G C DE     IME    G LK+YLQ+     +     I+  +  ++T QI  GM +L S  I+HRDLA RNIL+     +KI+DFG++R  +  Y  MS+   P RW++PE   +N ++ KSDVW++G++LWEI TLG  PY +++  ++ + +  G+  ++P      +Y LMK CW    + RP+F  I++++E +
Sbjct:  185 RGQDIVVGAVIGEGAFGQVFKGILRGPNGQVIPVAVKQLKANAIDEEREEFVREIQMMQTVGQHDNIVTMYGYCMDEQLQCMIMEYVPYGDLKHYLQNMRKEKDSD-SAIDSKEFLSFTNQIACGMAHLESVGIIHRDLAARNILVGTGKVLKISDFGMSRPGV--YIKMSKGVIPLRWLSPEAIKDNTYSNKSDVWAFGVLLWEIATLGGFPYNNVADKDILNQLTEGMRLEQPAKCSDDMYILMKSCWNLKAEDRPSFLAILSKIEQI 451

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BLAST of FGFR1 vs. Ensembl Celegans
Match: csk-1 (Tyrosine-protein kinase csk-1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECJ6])

HSP 1 Score: 172.94 bits (437), Expect = 5.271e-46
Identity = 95/278 (34.17%), Postives = 151/278 (54.32%), Query Frame = 3

Query: 1335 DYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQ---DMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            D  S+  ++ L I  N + V G  +G G FG V LG+  +R VA+K+    G    D L DE + M  +  H +++ L+G+  D+ +++ I E  + G+L + L+S           +   QL  + + I +GM YL SK IVHRDLA RN+LL ++   K++DFGL +   +  H  +    P +W APE    ++FT KSDVWS+GI+LWEIF+ G +PY  +   +V   I  G   + PE  P  ++ +M + W      RP+F  ++ +L ++
Sbjct:  266 DRTSVFRHAGLVISSNDIDV-GDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLDEAKFMVGLS-HPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGR------HALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTI 535

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Query: 1335 DYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQ---DMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            D  S+  ++ L I  N + V G  +G G FG V LG+  +R VA+K+    G    D L DE + M  +  H +++ L+G+  D+ +++ I E  + G+L + L+S           +   QL  + + I +GM YL SK IVHRDLA RN+LL ++   K++DFGL +   +  H  +    P +W APE    ++FT KSDVWS+GI+LWEIF+ G +PY  +   +V   I  G   + PE  P  ++ +M + W      RP+F  ++ +L ++
Sbjct:  266 DRTSVFRHAGLVISSNDIDV-GDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLDEAKFMVGLS-HPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGR------HALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTI 535

[Close]

BLAST of FGFR1 vs. Ensembl Celegans
Match: csk-1 (Tyrosine-protein kinase csk-1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECJ6])

HSP 1 Score: 173.326 bits (438), Expect = 1.333e-45
Identity = 95/278 (34.17%), Postives = 151/278 (54.32%), Query Frame = 3

Query: 1335 DYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQ---DMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            D  S+  ++ L I  N + V G  +G G FG V LG+  +R VA+K+    G    D L DE + M  +  H +++ L+G+  D+ +++ I E  + G+L + L+S           +   QL  + + I +GM YL SK IVHRDLA RN+LL ++   K++DFGL +   +  H  +    P +W APE    ++FT KSDVWS+GI+LWEIF+ G +PY  +   +V   I  G   + PE  P  ++ +M + W      RP+F  ++ +L ++
Sbjct:  351 DRTSVFRHAGLVISSNDIDV-GDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLDEAKFMVGLS-HPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGR------HALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTI 620

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Query: 1335 DYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQ---DMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            D  S+  ++ L I  N + V G  +G G FG V LG+  +R VA+K+    G    D L DE + M  +  H +++ L+G+  D+ +++ I E  + G+L + L+S           +   QL  + + I +GM YL SK IVHRDLA RN+LL ++   K++DFGL +   +  H  +    P +W APE    ++FT KSDVWS+GI+LWEIF+ G +PY  +   +V   I  G   + PE  P  ++ +M + W      RP+F  ++ +L ++
Sbjct:  351 DRTSVFRHAGLVISSNDIDV-GDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLDEAKFMVGLS-HPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGR------HALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTI 620

[Close]

BLAST of FGFR1 vs. Ensembl Fly
Match: htl (gene:FBgn0010389 transcript:FBtr0083550)

HSP 1 Score: 194.897 bits (494), Expect = 2.127e-52
Identity = 109/290 (37.59%), Postives = 165/290 (56.90%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQD----MLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL------------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFS-LSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
              ++S  E+PR+H+ V G  LGEG FG V +  V++  VA+K+  E   D     L  E+ +M+ IGRH +++ L+G C   G L+ I+E A  G+LK++L    P              + P   I    L  +  QI +GM+YL+S+  +HRDLA RN+L++++  +KIADFGL R +   +YY   +    P +WMAPE   E  + +KSDVWSYGI+LWEI T G  PY + +S  E+   + +G   +KP      +Y LM++CW F+ D RP F +IV  ++ +
Sbjct:  403 FPLDSNWELPRSHL-VLGATLGEGAFGRVVMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKL 691

[Close]

BLAST of FGFR1 vs. Ensembl Fly
Match: htl (gene:FBgn0010389 transcript:FBtr0083549)

HSP 1 Score: 194.897 bits (494), Expect = 2.127e-52
Identity = 109/290 (37.59%), Postives = 165/290 (56.90%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQD----MLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL------------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFS-LSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
              ++S  E+PR+H+ V G  LGEG FG V +  V++  VA+K+  E   D     L  E+ +M+ IGRH +++ L+G C   G L+ I+E A  G+LK++L    P              + P   I    L  +  QI +GM+YL+S+  +HRDLA RN+L++++  +KIADFGL R +   +YY   +    P +WMAPE   E  + +KSDVWSYGI+LWEI T G  PY + +S  E+   + +G   +KP      +Y LM++CW F+ D RP F +IV  ++ +
Sbjct:  403 FPLDSNWELPRSHL-VLGATLGEGAFGRVVMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKL 691

[Close]

BLAST of FGFR1 vs. Ensembl Fly
Match: htl (gene:FBgn0010389 transcript:FBtr0083548)

HSP 1 Score: 194.897 bits (494), Expect = 2.127e-52
Identity = 109/290 (37.59%), Postives = 165/290 (56.90%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQD----MLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL------------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFS-LSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
              ++S  E+PR+H+ V G  LGEG FG V +  V++  VA+K+  E   D     L  E+ +M+ IGRH +++ L+G C   G L+ I+E A  G+LK++L    P              + P   I    L  +  QI +GM+YL+S+  +HRDLA RN+L++++  +KIADFGL R +   +YY   +    P +WMAPE   E  + +KSDVWSYGI+LWEI T G  PY + +S  E+   + +G   +KP      +Y LM++CW F+ D RP F +IV  ++ +
Sbjct:  403 FPLDSNWELPRSHL-VLGATLGEGAFGRVVMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKL 691

[Close]

BLAST of FGFR1 vs. Ensembl Fly
Match: btl (gene:FBgn0285896 transcript:FBtr0100676)

HSP 1 Score: 189.119 bits (479), Expect = 1.532e-49
Identity = 107/312 (34.29%), Postives = 165/312 (52.88%), Query Frame = 3

Query: 1317 DVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP------------LINHP---CQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFS-LSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            D  Q  +     ++S  EIPR  + +  + LGEG FG V +   +            VA+K+  E+  D     L  E+ +M+ IG+H +++ L+G C   G LW I+E A  G+LK++L+   P            L + P    Q +   +L  +  QI +GM YL+S+  +HRDLA RN+L+++   +KIADFGL R +    YY   +    P +WMAPE   E ++ ++SDVWSYG++LWEI T G  PY   LS  E+   +  G   +KP      +Y +M++CW F+   RPTFA++V   + +
Sbjct:  689 DPAQGFNEYEFPLDSNWEIPRQQLSLGSI-LGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGI 999

[Close]

BLAST of FGFR1 vs. Ensembl Fly
Match: btl (gene:FBgn0285896 transcript:FBtr0075778)

HSP 1 Score: 189.119 bits (479), Expect = 1.532e-49
Identity = 107/312 (34.29%), Postives = 165/312 (52.88%), Query Frame = 3

Query: 1317 DVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP------------LINHP---CQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFS-LSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            D  Q  +     ++S  EIPR  + +  + LGEG FG V +   +            VA+K+  E+  D     L  E+ +M+ IG+H +++ L+G C   G LW I+E A  G+LK++L+   P            L + P    Q +   +L  +  QI +GM YL+S+  +HRDLA RN+L+++   +KIADFGL R +    YY   +    P +WMAPE   E ++ ++SDVWSYG++LWEI T G  PY   LS  E+   +  G   +KP      +Y +M++CW F+   RPTFA++V   + +
Sbjct:  689 DPAQGFNEYEFPLDSNWEIPRQQLSLGSI-LGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGI 999

[Close]

BLAST of FGFR1 vs. Ensembl Zebrafish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 193.741 bits (491), Expect = 1.161e-54
Identity = 108/303 (35.64%), Postives = 162/303 (53.47%), Query Frame = 3

Query: 1320 VIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            ++ N   + L  + K E  R  + + G  LGEG FG V +      D         VA+K+  + G D     L  E+ MM+ IG+H++++ L+G C  +G L+ ++E AS G+L+ YL++  P            P + +    L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWSYG++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M++CW      RPTF  +V   + V
Sbjct:   20 MLPNVSELELPSDPKWEFTRTKLTL-GKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRV 321

[Close]

BLAST of FGFR1 vs. Ensembl Zebrafish
Match: fgfr1b (fibroblast growth factor receptor 1b [Source:ZFIN;Acc:ZDB-GENE-060503-14])

HSP 1 Score: 197.593 bits (501), Expect = 5.250e-53
Identity = 106/277 (38.27%), Postives = 155/277 (55.96%), Query Frame = 3

Query: 1392 VSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINH--------PCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLE 2153
            V G  LGEG FG V +G     D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YL++  P            P + +++  L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP    + +Y +MK CW      RPTF  +V  L+
Sbjct:  424 VLGKPLGEGCFGQVVMGEAIGLDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPHGMEYCYNPDPLPIESMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLREGHRMDKPSACTQELYLMMKDCWHAVPTQRPTFKQLVEDLD 700

[Close]

BLAST of FGFR1 vs. Ensembl Zebrafish
Match: fgfr1b (fibroblast growth factor receptor 1b [Source:ZFIN;Acc:ZDB-GENE-060503-14])

HSP 1 Score: 197.208 bits (500), Expect = 5.366e-53
Identity = 106/277 (38.27%), Postives = 155/277 (55.96%), Query Frame = 3

Query: 1392 VSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINH--------PCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLE 2153
            V G  LGEG FG V +G     D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YL++  P            P + +++  L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP    + +Y +MK CW      RPTF  +V  L+
Sbjct:  398 VLGKPLGEGCFGQVVMGEAIGLDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPHGMEYCYNPDPLPIESMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLREGHRMDKPSACTQELYLMMKDCWHAVPTQRPTFKQLVEDLD 674

[Close]

BLAST of FGFR1 vs. Ensembl Zebrafish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 194.512 bits (493), Expect = 7.398e-52
Identity = 115/333 (34.53%), Postives = 176/333 (52.85%), Query Frame = 3

Query: 1251 LRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRN------HVKVS-GVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L+R   L++++ +     LV    + + D   L   S+LE+P +        K++ G  LGEG FG V +      D         VA+K+  + G D     L  E+ MM+ IG+H++++ L+G C  +G L+ ++E AS G+L+ YL++  P            P + +    L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWSYG++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M++CW      RPTF  +V   + V
Sbjct:  407 LKRQVSLESNSSMNSNTPLVRIARLSSSDGPMLPNVSELELPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRV 739

[Close]

BLAST of FGFR1 vs. Ensembl Zebrafish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 194.897 bits (494), Expect = 7.849e-52
Identity = 115/333 (34.53%), Postives = 176/333 (52.85%), Query Frame = 3

Query: 1251 LRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRN------HVKVS-GVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L+R   L++++ +     LV    + + D   L   S+LE+P +        K++ G  LGEG FG V +      D         VA+K+  + G D     L  E+ MM+ IG+H++++ L+G C  +G L+ ++E AS G+L+ YL++  P            P + +    L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWSYG++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M++CW      RPTF  +V   + V
Sbjct:  426 LKRQVSLESNSSMNSNTPLVRIARLSSSDGPMLPNVSELELPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRV 758

[Close]

BLAST of FGFR1 vs. Ensembl Xenopus
Match: fgfr4 (fibroblast growth factor receptor 4 [Source:NCBI gene;Acc:549077])

HSP 1 Score: 200.675 bits (509), Expect = 4.410e-54
Identity = 110/296 (37.16%), Postives = 167/296 (56.42%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLG---SVDSR------DVAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            + L +++K E PR+ + V G  LGEG FG V       +D         VA+K+  + G D     L  E+ +M+ IG+H++++ L+G+C  EG L+ I+E AS G+L+ +L++  P        +   P + ++   L +   Q+ +GM YL SK  +HRDLA RN+L+AE+  +KIADFGL R V  I+YY   S    P +WMAPE   +  +T +SD+WS+G++ WEIFTLG  PY  +   E+   +  G   DKP      +Y LM++CW      RPTF  +V QL+ +
Sbjct:  381 VELPLDAKWEFPRDRL-VLGKPLGEGCFGQVVRAEGYGIDKERPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIVEYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDLAARNVLVAEDNVMKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDIWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECWHAVPSQRPTFKQLVEQLDRI 675

[Close]

BLAST of FGFR1 vs. Ensembl Xenopus
Match: fgfr4 (fibroblast growth factor receptor 4 [Source:NCBI gene;Acc:549077])

HSP 1 Score: 201.06 bits (510), Expect = 8.594e-54
Identity = 110/296 (37.16%), Postives = 167/296 (56.42%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLG---SVDSR------DVAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            + L +++K E PR+ + V G  LGEG FG V       +D         VA+K+  + G D     L  E+ +M+ IG+H++++ L+G+C  EG L+ I+E AS G+L+ +L++  P        +   P + ++   L +   Q+ +GM YL SK  +HRDLA RN+L+AE+  +KIADFGL R V  I+YY   S    P +WMAPE   +  +T +SD+WS+G++ WEIFTLG  PY  +   E+   +  G   DKP      +Y LM++CW      RPTF  +V QL+ +
Sbjct:  479 VELPLDAKWEFPRDRL-VLGKPLGEGCFGQVVRAEGYGIDKERPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIVEYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDLAARNVLVAEDNVMKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDIWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECWHAVPSQRPTFKQLVEQLDRI 773

[Close]

BLAST of FGFR1 vs. Ensembl Xenopus
Match: fgfr4 (fibroblast growth factor receptor 4 [Source:NCBI gene;Acc:549077])

HSP 1 Score: 200.675 bits (509), Expect = 8.613e-54
Identity = 110/296 (37.16%), Postives = 167/296 (56.42%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLG---SVDSR------DVAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            + L +++K E PR+ + V G  LGEG FG V       +D         VA+K+  + G D     L  E+ +M+ IG+H++++ L+G+C  EG L+ I+E AS G+L+ +L++  P        +   P + ++   L +   Q+ +GM YL SK  +HRDLA RN+L+AE+  +KIADFGL R V  I+YY   S    P +WMAPE   +  +T +SD+WS+G++ WEIFTLG  PY  +   E+   +  G   DKP      +Y LM++CW      RPTF  +V QL+ +
Sbjct:  448 VELPLDAKWEFPRDRL-VLGKPLGEGCFGQVVRAEGYGIDKERPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIVEYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDLAARNVLVAEDNVMKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDIWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECWHAVPSQRPTFKQLVEQLDRI 742

[Close]

BLAST of FGFR1 vs. Ensembl Xenopus
Match: fgfr4 (fibroblast growth factor receptor 4 [Source:NCBI gene;Acc:549077])

HSP 1 Score: 201.06 bits (510), Expect = 9.678e-54
Identity = 110/296 (37.16%), Postives = 166/296 (56.08%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            + L +++K E PR+ + V G  LGEG FG V        D         VA+K+  + G D     L  E+ +M+ IG+H++++ L+G+C  EG L+ I+E AS G+L+ +L++  P        +   P + ++   L +   Q+ +GM YL SK  +HRDLA RN+L+AE+  +KIADFGL R V  I+YY   S    P +WMAPE   +  +T +SD+WS+G++ WEIFTLG  PY  +   E+   +  G   DKP      +Y LM++CW      RPTF  +V QL+ +
Sbjct:  473 VELPLDAKWEFPRDRL-VLGKPLGEGCFGQVVRAEGYGIDKERPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIVEYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDLAARNVLVAEDNVMKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDIWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECWHAVPSQRPTFKQLVEQLDRI 767

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BLAST of FGFR1 vs. Ensembl Xenopus
Match: fgfr4 (fibroblast growth factor receptor 4 [Source:NCBI gene;Acc:549077])

HSP 1 Score: 200.675 bits (509), Expect = 1.063e-53
Identity = 110/296 (37.16%), Postives = 166/296 (56.08%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            + L +++K E PR+ + V G  LGEG FG V        D         VA+K+  + G D     L  E+ +M+ IG+H++++ L+G+C  EG L+ I+E AS G+L+ +L++  P        +   P + ++   L +   Q+ +GM YL SK  +HRDLA RN+L+AE+  +KIADFGL R V  I+YY   S    P +WMAPE   +  +T +SD+WS+G++ WEIFTLG  PY  +   E+   +  G   DKP      +Y LM++CW      RPTF  +V QL+ +
Sbjct:  447 VELPLDAKWEFPRDRL-VLGKPLGEGCFGQVVRAEGYGIDKERPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIVEYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDLAARNVLVAEDNVMKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDIWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECWHAVPSQRPTFKQLVEQLDRI 741

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BLAST of FGFR1 vs. Ensembl Mouse
Match: Fgfr2 (fibroblast growth factor receptor 2 [Source:MGI Symbol;Acc:MGI:95523])

HSP 1 Score: 199.519 bits (506), Expect = 1.589e-54
Identity = 108/294 (36.73%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSV---------DSRDVAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL-------INH-PCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + K E PR+ + + G  LGEG FG V +            ++  VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YL++  P        IN  P +++    L + T Q+ +GM YL+S+  +HRDLA RN+L+ EN  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G+++WEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  256 LPEDPKWEFPRDKLTL-GKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 548

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BLAST of FGFR1 vs. Ensembl Mouse
Match: Fgfr2 (fibroblast growth factor receptor 2 [Source:MGI Symbol;Acc:MGI:95523])

HSP 1 Score: 199.134 bits (505), Expect = 1.776e-54
Identity = 108/294 (36.73%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSV---------DSRDVAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL-------INH-PCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + K E PR+ + + G  LGEG FG V +            ++  VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YL++  P        IN  P +++    L + T Q+ +GM YL+S+  +HRDLA RN+L+ EN  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G+++WEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  255 LPEDPKWEFPRDKLTL-GKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 547

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BLAST of FGFR1 vs. Ensembl Mouse
Match: Fgfr1 (fibroblast growth factor receptor 1 [Source:MGI Symbol;Acc:MGI:95522])

HSP 1 Score: 200.29 bits (508), Expect = 4.891e-54
Identity = 109/294 (37.07%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL--------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + + E+PR+ + V G  LGEG FG V L      D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YLQ+  P          ++P ++++   L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  376 LPEDPRWELPRDRL-VLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 668

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Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL--------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + + E+PR+ + V G  LGEG FG V L      D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YLQ+  P          ++P ++++   L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  376 LPEDPRWELPRDRL-VLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 668

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Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL--------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + + E+PR+ + V G  LGEG FG V L      D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YLQ+  P          ++P ++++   L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  376 LPEDPRWELPRDRL-VLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 668

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BLAST of FGFR1 vs. UniProt/SwissProt
Match: sp|Q8MY86|FGFR1_DUGJA (Fibroblast growth factor receptor 1 OS=Dugesia japonica OX=6161 GN=FGFR1 PE=2 SV=1)

HSP 1 Score: 228.024 bits (580), Expect = 2.245e-62
Identity = 121/279 (43.37%), Postives = 177/279 (63.44%), Query Frame = 3

Query: 1356 NSKLEIPRNHVKVSGVKLGEGNFGTVFLG---SVDSRDVAIKIPTEQGQDMLFD--------EVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEIN---LNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQL 2150
            ++K E PR  +K++  KLGEG FG V+ G    + +R   IK+  +  +D   D        E+ +M+ IGRH +V++L+GLC  +G L  I+ELA  G+L++++++ N   +   + I     + L TY+LQI +GM YL+S+S+VHRDL+ RNIL+ E+ ++KIADFGLTRIV  YY   ++   P +WMAPE  +E ++T KSDVWSYGI+LWEIFTLG  PY ++   +V D I  G  N KPE++   +Y LM+ CW    + RP F +IV  L
Sbjct:  540 DAKWEFPREKLKITNKKLGEGAFGMVYEGIANDIGNRSNPIKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQKGPLRVIVELAPYGNLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQIARGMTYLASRSVVHRDLSARNILVGEHFEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVVDLIRKGFQNPKPELANFEIYRLMQHCWSLSSENRPNFFEIVEIL 818

HSP 2 Score: 63.5438 bits (153), Expect = 5.432e-9
Identity = 91/364 (25.00%), Postives = 154/364 (42.31%), Query Frame = 3

Query:  171 SKLEYQTAR---LSCHINVIKRCRKGSVRWAWFKDN----IQIKNGTRKKTRSQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNRDRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIK-NGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEK-LRFTGNSTICAGQKFIFNCSTE----------------------KYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISE----RMMHLTVIPC 1157
            +KL ++T+    L+C   V ++C+K  ++  W+KDN     +I+ G + K R +  ++       ++D+G Y C V N   N S +    ++V   E   +  N + L+ S +     Y  P+M  E Y +    E+     +QC+FFS   +N+ +V WY      N  +     +L+   S++ I +   +C Q    +I  +  C  S  +    S      TC I    N   +      +   VD  +   L F  +ST+C G  F   C T                         S++ LF+   N+NE    +S    E+++K  D   +G YLC   S++E     +MHL+VI C
Sbjct:   36 NKLNWRTSEEMVLTCKAVVNEKCKKSKLQMRWYKDNELLGKKIERGLKMKYRYRKKLK-------LNDSGNYTCFVFNKNGNSSVF--FLINVTEKENFHVNENKI-LDGSEISNNTLYLHPEMGMENYHVIPNDEIV----MQCRFFSPISINL-TVSWYQHSCDSNYHN----AQLLVKDSKFNISSNKESC-QSYLSHIPLDSICLYSWLRFIATSDDQSCITCLIESDNNSIEKTKFTFTVL--VDAGHRPHLTFAPSSTVCQGSNFTMKCETNVPRPILYIYKLDPSFNIENPIIHLSNSTLFV--NNYNEDSKRSSQS-AEVLIKSMDFNYSGRYLC---SLAELPLFEIMHLSVIKC 371

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BLAST of FGFR1 vs. UniProt/SwissProt
Match: sp|Q8MY85|FGFR2_DUGJA (Fibroblast growth factor receptor 2 OS=Dugesia japonica OX=6161 GN=FGFR2 PE=2 SV=1)

HSP 1 Score: 214.542 bits (545), Expect = 1.771e-57
Identity = 114/277 (41.16%), Postives = 169/277 (61.01%), Query Frame = 3

Query: 1398 GVKLGEGNFGTVFLGSVDS-------RDVAIK-IPTEQG-QDM--LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYL------------QSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            G K+GEG FG V+   V S        +VAIK + T  G QD+  L  E+ MM+ IGRHRH++ L G C D G  + ++ELA  G+L+++L            Q+   L+      + +     ++++I +GM YLSS+ I+HRDLA RN+L+ +  ++KIADFGLTRIV NYY   ++   P +WMAPEC ++  +T KSDVWSYGIVLWEIFT+G  PY ++  + +  A+ NG+ N+KP ++   +Y LM   W  D   R TF++I+++L  +
Sbjct:  588 GSKIGEGAFGIVYSALVKSFSENSASVEVAIKTLHTSFGDQDVINLIQELEMMKIIGRHRHIISLYGACIDNGHPYMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGGLVT----RLTVTDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQYVEMKIADFGLTRIVENYYRKTTDGRLPIKWMAPECLLDRVYTVKSDVWSYGIVLWEIFTMGQTPYPTIQSDGMHQALRNGIRNEKPALASDEMYRLMLTIWNDDPLERHTFSEIIDKLTHI 860

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BLAST of FGFR1 vs. UniProt/SwissProt
Match: sp|Q91147|FGFR2_NOTVI (Fibroblast growth factor receptor 2 OS=Notophthalmus viridescens OX=8316 GN=FGFR2 PE=2 SV=1)

HSP 1 Score: 199.134 bits (505), Expect = 6.856e-53
Identity = 109/294 (37.07%), Postives = 163/294 (55.44%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSV---------DSRDVAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL-------INH-PCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + K E PR  + + G  LGEG FG V +            D+  VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YL++  P        IN  P +++    L + T Q+ +GM YL+S+  +HRDLA RN+L+ E   +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G+++WEIFTLG  PY  +   E+   +  G   DKP      +Y +M  CWR     RPTF  +V  L+ +
Sbjct:  376 LPEDPKWEYPREKLTL-GKPLGEGCFGQVVMAEAVGIDKDRPKDAATVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRTRRPPGMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTETNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYTMMTDCWRAVPSQRPTFKQLVEDLDRI 668

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BLAST of FGFR1 vs. UniProt/SwissProt
Match: sp|P16092|FGFR1_MOUSE (Fibroblast growth factor receptor 1 OS=Mus musculus OX=10090 GN=Fgfr1 PE=1 SV=2)

HSP 1 Score: 200.29 bits (508), Expect = 8.598e-53
Identity = 109/294 (37.07%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL--------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + + E+PR+ + V G  LGEG FG V L      D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YLQ+  P          ++P ++++   L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  465 LPEDPRWELPRDRL-VLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757

[Close]

BLAST of FGFR1 vs. UniProt/SwissProt
Match: sp|P11362|FGFR1_HUMAN (Fibroblast growth factor receptor 1 OS=Homo sapiens OX=9606 GN=FGFR1 PE=1 SV=3)

HSP 1 Score: 200.29 bits (508), Expect = 9.547e-53
Identity = 109/294 (37.07%), Postives = 165/294 (56.12%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL--------INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L  + + E+PR+ + V G  LGEG FG V L      D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YLQ+  P          ++P ++++   L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+ +
Sbjct:  465 LPEDPRWELPRDRL-VLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757

[Close]

BLAST of FGFR1 vs. TrEMBL
Match: H9CXV7 (Receptor protein-tyrosine kinase OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 640.188 bits (1650), Expect = 0.000e+0
Identity = 307/311 (98.71%), Postives = 308/311 (99.04%), Query Frame = 3

Query:   48 MIKFNSSHFYWFIFIVEIVNGMFDFPSTDSCYEIRTFESKLSKLEYQTARLSCHINVIKRCRKGSVRWAWFKDNIQIKNGTRKKTRSQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNRDRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEK 980
            MIKFNSSHFYWFIFIVEIVNGMFDFPSTDSCYEIRTFESKLSKLEYQTARLSCHINVIKRCRKGSVRWAWFKDNIQIKNGT+KKTRSQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGS GHVNNRDRRTFGELIKTG  YEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEK
Sbjct:    1 MIKFNSSHFYWFIFIVEIVNGMFDFPSTDSCYEIRTFESKLSKLEYQTARLSCHINVIKRCRKGSVRWAWFKDNIQIKNGTQKKTRSQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSLGHVNNRDRRTFGELIKTGXXYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEK 311

HSP 2 Score: 271.552 bits (693), Expect = 2.612e-79
Identity = 127/129 (98.45%), Postives = 129/129 (100.00%), Query Frame = 3

Query: 1368 EIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIV 1754
            EIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKS++
Sbjct:  312 EIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSVI 440

[Close]

BLAST of FGFR1 vs. TrEMBL
Match: T1G069 (Protein kinase domain-containing protein OS=Helobdella robusta OX=6412 GN=20214467 PE=3 SV=1)

HSP 1 Score: 218.779 bits (556), Expect = 2.224e-61
Identity = 120/298 (40.27%), Postives = 174/298 (58.39%), Query Frame = 3

Query: 1335 DYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGS---VDSRD------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVI--NYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            DY  + ++   E PR  ++VS + LGEG FGTV++ +   VDS +      VA+K+  E   D     L  E+ MM+ IGRH++VL L+G C   G L+ I+E A+ G+L+++L+   P        ++  P   +    L T+ LQI KGM +L+SK  +HRDLA RN+L+ E+  +K+ADFGLTR V+  +YY   ++   P +WMAPE   + + T KSDVWSYGI+LWE+F+LG  PY S+   ++   +  G   + P  S   +Y LM  CW    D RP+F  IVN L SV
Sbjct:    2 DY-EIPLDKAWEFPREKLQVSSI-LGEGAFGTVYMATAVGVDSSNPEASTKVAVKMLKENASDQDVVDLVQEMEMMKIIGRHKNVLSLLGCCTQNGPLFVILEYAANGNLRDFLRDKRPKNFRLQNCVVEVPLDYLTYKDLVTFALQIAKGMEFLASKMCIHRDLAARNVLVCEDYTLKVADFGLTRNVLKSDYYKKKTDGRLPVKWMAPEALFDRKCTVKSDVWSYGILLWELFSLGGNPYPSVPVEKIFQLLKAGYRMEAPVYSSNEIYSLMLSCWHQSPDHRPSFNKIVNSLHSV 297

[Close]

BLAST of FGFR1 vs. TrEMBL
Match: H9CXV6 (FGFR4 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 230.335 bits (586), Expect = 1.004e-60
Identity = 120/278 (43.17%), Postives = 173/278 (62.23%), Query Frame = 3

Query: 1368 EIPRNHVKVSGVKLGEGNFGTVFLG---SVDSRDVAIKIPTEQGQDMLFD--------EVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEI-NLNQ--LFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            E PR+ +K++  KLGEG FG V+ G    +  +    K+  +  +D   D        E+ +M+ IGRH +V++L+GLC   G L  I+ELA  G+L+++++S N   +   + I NL    L TY+ QI  GM YL+S+S+VHRDL+ RNIL+ E+ ++KIADFGLTRIV  YY   ++   P +WMAPE  +E ++T KSDVWSYGI+LWEIFTLG  PY S+   +V D I  G  N +PE++   +Y LM+ CW    + RP F +IV  L+ +
Sbjct:  531 EFPRDKLKITNKKLGEGAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENLTASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVVDVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETLQDI 808

HSP 2 Score: 62.003 bits (149), Expect = 5.394e-6
Identity = 86/356 (24.16%), Postives = 138/356 (38.76%), Query Frame = 3

Query:  195 RLSCHINVIKRCRKGSVRWAWFKDNIQIKNGTRKKTRSQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIR-LNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNRDRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNG-TCYDSDFK-INPYSKLYKYYTCAIGG------QLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFL-----IRKNHNEIILNTSVGRVEMVLKFADST----------------DTGIYLCR-----RESISERMMHLTVIPC 1157
             L C + V   C+   +   W KD   +  G + K   ++   +      +SD G Y C V N     S    + V+      K+I   + +P ++  + + + Y  P+M      + +   LS+ + L CQ    +K     + WY    H +  +    G+++ +  E  I+T   +C     LNI N   C  S+F  I P +    ++TC I        +   T+ I +   IFR       KL+F    T+C G  F  NCST +     L        R + N + L TS    E+V    DST                D+G Y C       +     +M+LTV+ C
Sbjct:   18 ELMCMVKVDISCQVTWLAMEWLKDGTFL--GKKVKILRKMKYIYKKKKLNVSDAGNYTCKVNNQFGESSLSYLVKVTEALSGSKLIENFHEIPSDLLEISQYKYYMHPEMKKG--NVKHVLSLSSIF-LNCQVL-FSKELYPRISWYQHSSHFDYEN----GKVLSSDDELFIETSEESCIPYTNLNISNDFICISSNFNYIVPDTFTETFFTCMIESNTSFVNKAKYTYVILIDQRIFRN------KLKFPKQLTVCHGSNFTLNCSTNEPRPVLLLFKLQPKSRLDLNNVDLRTSPLLTELVSN--DSTRSLKSMIWRFYSVSFNDSGRYFCTISPHVPDETQYELMNLTVVDC 355

[Close]

BLAST of FGFR1 vs. TrEMBL
Match: A0A0R3UM39 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS8788 PE=4 SV=1)

HSP 1 Score: 216.853 bits (551), Expect = 4.849e-59
Identity = 111/267 (41.57%), Postives = 161/267 (60.30%), Query Frame = 3

Query: 1368 EIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL-----INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLE 2153
            E+PR+ V++ G ++G G FG V+ G+V         PT++  D L  E+ +++Q   H HV++L G+C   G L  ++ELA  G+L+++L    P       N P   ++   L ++ LQ+ KGM+YL+ ++I+HRDLA RNIL+      KIADFGLTR V +YY   S+   P +WMAPE   + R+T KSDVWS+GI+LWEIF+ G  PY +LS   +  A+  G  N++P  SP  VY LM  CW  D   RPTF+ +V  L+
Sbjct:   51 EVPRDRVRL-GRQIGAGAFGVVYEGTVSD-------PTKELAD-LVREMEILKQFNPHPHVIQLYGVCTQNGRLQVLVELAPYGNLRDFLMDRRPRRDQKSANQPFSHLSARHLVSFGLQVAKGMDYLARQNIIHRDLAARNILIGCRFVAKIADFGLTRSVCDYYRKCSDGRLPIKWMAPESIFDRRYTTKSDVWSFGILLWEIFSYGGTPYPTLSAESLLKALQMGFRNEQPLASPSHVYGLMLSCWSIDPACRPTFSQLVASLQ 308

[Close]

BLAST of FGFR1 vs. TrEMBL
Match: A0A158RDD1 (Protein kinase domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS394 PE=4 SV=1)

HSP 1 Score: 217.624 bits (553), Expect = 1.381e-56
Identity = 118/297 (39.73%), Postives = 169/297 (56.90%), Query Frame = 3

Query: 1368 EIPRNHVKVSGVKLGEGNFGTVFLG-----------------------SVDSRDVAIKIP----TEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP-----LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESVN 2162
            E+PR+ V++ G ++G G FG VF G                       S     VA+K      TEQ    L  E+ +++Q   H HV++L G+C   G L  ++ELA  G+L+++L    P     +IN P   ++   L ++ LQ+ +GM+YL+  +IVHRDLA RNIL+      KIADFGLTR V +YY   S+   P +WMAPE   + R+TAKSDVWS+GI+LWEIF+ G  PY +LS   +  A+  G+ N++P  SP  VY+LM  CW  D   RP+FA +V+ L+ V+
Sbjct:  327 EVPRDCVRL-GRQIGAGAFGVVFAGVISEPAKVLPGLRRGDPLDRSCCSAQELTVAVKTLRNNFTEQELADLVREMEILKQFEPHPHVIQLYGVCTQNGRLQMLVELAPYGNLRDFLMDRRPCAGQKMINQPLPRLSTGHLVSFGLQVARGMDYLARLNIVHRDLAARNILIGNRFVAKIADFGLTRSVCDYYRKCSDGRLPIKWMAPESIFDRRYTAKSDVWSFGILLWEIFSFGGTPYPTLSAEALLKALQLGLRNEQPLASPASVYNLMLACWSIDPAARPSFAHLVSSLQQVH 622

[Close]

BLAST of FGFR1 vs. Ensembl Cavefish
Match: fgfr1a (fibroblast growth factor receptor 1a [Source:NCBI gene;Acc:30705])

HSP 1 Score: 200.29 bits (508), Expect = 3.935e-54
Identity = 108/292 (36.99%), Postives = 164/292 (56.16%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINH--------PCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLE 2153
            L  + + E+PR+ + V G  LGEG FG V +G V   D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YL++  P            P + +++  L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   D+P      +Y +M+ CW      RPTF  +V  L+
Sbjct:  377 LPQDPRWELPRDKL-VLGKPLGEGCFGQVVMGEVLGMDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPTTCTHELYMMMRDCWHAIPSQRPTFKQLVEDLD 667

[Close]

BLAST of FGFR1 vs. Ensembl Cavefish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 197.208 bits (500), Expect = 1.115e-52
Identity = 118/334 (35.33%), Postives = 176/334 (52.69%), Query Frame = 3

Query: 1251 LRRAFQLK-----NSNRVYV-TRRLVLKD--VIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            L+R   L+     NSN   V   RL   D  ++ N   + L  + K E PR+ + + G  LGEG FG V +      D         VA+K+  + G D     L  E+ MM+ IG+H++++ L+G C  +G L+ ++E AS G+L+ YL++  P            P + +    L +   Q+ +GM YL+S+  +HRDLA RN+L+ E+  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWSYG++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M++CW      RPTF  +V   + V
Sbjct:  422 LKRQVSLESNSSMNSNTPLVRIARLSSSDGPMLPNVSELELPSDPKWEFPRSKLTL-GKALGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRV 754

[Close]

BLAST of FGFR1 vs. Ensembl Cavefish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 196.823 bits (499), Expect = 1.250e-52
Identity = 115/321 (35.83%), Postives = 171/321 (53.27%), Query Frame = 3

Query: 1275 NSNRVYV-TRRLVLKD--VIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            NSN   V   RL   D  ++ N   + L  + K E PR+ + + G  LGEG FG V +      D         VA+K+  + G D     L  E+ MM+ IG+H++++ L+G C  +G L+ ++E AS G+L+ YL++  P            P + +    L +   Q+ +GM YL+S+  +HRDLA RN+L+ E+  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWSYG++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M++CW      RPTF  +V   + V
Sbjct:  434 NSNTPLVRIARLSSSDGPMLPNVSELELPSDPKWEFPRSKLTL-GKALGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRV 753

[Close]

BLAST of FGFR1 vs. Ensembl Cavefish
Match: fgfr4 (fibroblast growth factor receptor 4 [Source:NCBI gene;Acc:103029904])

HSP 1 Score: 193.356 bits (490), Expect = 4.640e-51
Identity = 105/296 (35.47%), Postives = 164/296 (55.41%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSV-----DSRD----VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            I L  +   E PR ++ + G  LGEG FG V          D++D    VA+K+  +   D     L  E+ +M+ + +H++++ L+G+C  +G L+ ++E AS GSL+ YL++  P        +   P +++    L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWS+G+++WEIFTLG  PY  +   E+   +  G   DKP      +Y  M++CW      RPTF  +V +L+ V
Sbjct:  579 IELPYDPDWEFPRENLTL-GKPLGEGCFGQVVRADAYGINKDNQDQATTVAVKMLKDDATDKDLADLISEMELMKGMDKHKNIINLLGVCTQDGPLYVLVEYASKGSLREYLRARRPPGMDYTFDVTKVPEEQLTFKDLLSCAYQVARGMEYLASKRCIHRDLAARNVLVTEDNVMKIADFGLARGVHQIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPSNCTHELYMKMRECWHAVPTQRPTFKQLVEELDRV 873

[Close]

BLAST of FGFR1 vs. Ensembl Cavefish
Match: fgfr2 (fibroblast growth factor receptor 2 [Source:NCBI gene;Acc:352940])

HSP 1 Score: 191.815 bits (486), Expect = 5.380e-51
Identity = 112/312 (35.90%), Postives = 169/312 (54.17%), Query Frame = 3

Query: 1293 VTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSV---------DSRDVAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
             TRR    D I  P+Y  L  + + E  R+ + + G  LGEG FG V +            ++  VA+K+     TE+    L  E+ MM+ IGRH++++ L+G C  +G L+ I+E AS G+L+ YL++  P        +     + +    L + T Q+ +GM YL+S+  +HRDLA RN+L+ E+  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWS+G+++WEIFTLG  PY  +   E+   +  G   DKP      +Y +MK CW      RPTF  +V  L+ +
Sbjct:  416 TTRRSSDHDQII-PEY-DLPEDPRWEFSRDKLTL-GKPLGEGCFGQVVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNDLYMMMKDCWHAISSQRPTFKQLVEDLDRI 724

[Close]

BLAST of FGFR1 vs. Ensembl Sea Lamprey
Match: fgfr2 (fibroblast growth factor receptor 2 [Source:NCBI gene;Acc:352940])

HSP 1 Score: 192.971 bits (489), Expect = 5.827e-53
Identity = 101/278 (36.33%), Postives = 155/278 (55.76%), Query Frame = 3

Query: 1398 GVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP---------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            G  LGEG FG V +      D         VA+K+  E   D     L  E+ MM+ IG+H++++ L+G C   G L+ I+E A+ G+L+ +L++  P               +++++ +L ++T Q+ +GM YL+SK  +HRDLA RN+L+ ++  +KIADFGL R V  I+YY   S    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   D+P +    +Y +MK CW      RPTF  +V  L+ +
Sbjct:  279 GKPLGEGCFGQVVMAEALGIDKEKPNRSLRVAVKMLKEDATDKDLYDLVSEMEMMKNIGKHKNIINLLGACTQGGPLYVIVEFAAKGNLREFLRARRPPGTEYTFEGAAAAQGEQLSIKELVSFTYQVARGMEYLASKKCIHRDLAARNVLVTDDNVMKIADFGLARDVNYIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDRPALCSTELYMMMKDCWAAVPSHRPTFKQLVEDLDRI 556

[Close]

BLAST of FGFR1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006670.1 (pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene:ENSPMAG00000006016.1 transcript:ENSPMAT00000006670.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 181.03 bits (458), Expect = 9.315e-51
Identity = 112/303 (36.96%), Postives = 170/303 (56.11%), Query Frame = 3

Query: 1272 KNSNRVYVT-RRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVD-SRDVAIKIPTEQG---QDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVI----NYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLE 2153
            +++N + VT  +  LK  +   + +S  +  K EIPR+ V++   +LG G FG V+ G  + +  VAIK   +QG   +D    E ++M+++ RH  +++L  +C  E  ++ I EL S GSL NYLQ+         + ++L +L     Q+  GM YL +++ +HRDLA RNIL+AE+   K+ADFGL R++     + Y +      P +W APE    NRF+ KSDVWS+G++L EI T G +PY   +  EV  A+  G     P   P+  YDLM +CW  D+  RPTF  +  QLE
Sbjct:   75 RDANGLCVTLNQPCLKKEMPQTEGLSSDMADKWEIPRSSVQLVK-RLGAGQFGEVWQGLWNKTTPVAIKT-LKQGTMDRDDFLREAQLMKRL-RHPKLIQLYAVCTQEEPIYIITELMSNGSLANYLQTPE------GRSLDLVELVDMAAQVAAGMAYLEAQNYIHRDLAARNILVAEHNACKVADFGLARVIKMSNEDEYEARVGSKFPIKWTAPEAANYNRFSIKSDVWSFGVLLHEIITYGKLPYPGQTNAEVLAAVDRGYRMPCPPGCPQAFYDLMLECWNVDDQARPTFETLQWQLE 368

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BLAST of FGFR1 vs. Ensembl Sea Lamprey
Match: NTRK2 (neurotrophic receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:8032])

HSP 1 Score: 179.489 bits (454), Expect = 2.243e-50
Identity = 110/309 (35.60%), Postives = 155/309 (50.16%), Query Frame = 3

Query: 1320 VIQNPDYIS--LAINSKLEIPR----NHVKVSGV----KLGEGNFGTVFLGSVDSRDVA----------IKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP----LINHPCQEINL---NQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            VI+NP Y S  L       IP     +H+K   +    +LGEG FG V+L    S DV           +K  ++  +   + E  ++  + +H H++   G+C +   L  + E    G L  +L+   P    + + P  E  L    Q+     QI  GM YL+S+  VHRDLATRN L+     +KI DFG++R V   +YY        P RWM PE  +  +FTA SDVWS G+VLWEIFT G  P++ LS  EV D IC G + ++P   P  VY+LM  CW  +   R    DI+ +LES+
Sbjct:   43 VIENPQYFSDSLGPGKDAHIPEGYTAHHIKRQDIALMCELGEGAFGKVYLAECSSLDVGQEPMLVAAKTLKDLSDGARKDFYREAELLTNL-QHEHIVRFYGVCVEGEPLIMVFEYMKNGDLNKFLRLRGPDAVFMGDAPQAEPRLLSQAQMLNMGSQIAAGMAYLASQHFVHRDLATRNCLVGAGLVVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTADSDVWSLGVVLWEIFTYGKQPWYQLSNTEVIDCICQGRVLERPRSCPMEVYELMLGCWHREPQHRLGIKDILARLESL 350

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BLAST of FGFR1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004129.1 (pep scaffold:Pmarinus_7.0:GL490249:304:4500:1 gene:ENSPMAG00000003774.1 transcript:ENSPMAT00000004129.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 173.326 bits (438), Expect = 3.637e-49
Identity = 96/268 (35.82%), Postives = 149/268 (55.60%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSV-DSRDVAIKI-PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADI 2138
            +S+ + +   +PR+ +K+  + LG GNFG V+ G   D+ DVAIKI  T    D    EV+ M    +H +VL++  +C ++   W + EL   G++ +YL        H   E+   +       I  GM YLS K  +H DLA RNIL+ ++   K+ADFGL+  +   Y+  +    PF+WMAPE  ++ +FT KSDVWS+G++L+E+FT G  PY  +   +V+D I  G    +P+  P  VY +M++CW F+   RP F  +
Sbjct:    8 LSVELMNTWHVPRSSIKMGNL-LGRGNFGEVYEGRWNDTTDVAIKIVRTNSSFDTFMKEVKTMISF-KHENVLQIYAVCKEKWPYWIVTELVPYGNMLHYLGR----FGHELSEV---ERLYMAFGIASGMAYLSKKRCIHCDLAGRNILMGQHNICKVADFGLSHKLKEEYYDATGHVVPFQWMAPEVLIQLKFTRKSDVWSFGVLLYELFTDGKRPYADMDKQQVQDLIKCGGRLKRPDACPNVVYHIMQRCWNFEHRKRPPFCKL 266

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BLAST of FGFR1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009481.1 (pep scaffold:Pmarinus_7.0:GL477866:614:5163:1 gene:ENSPMAG00000008570.1 transcript:ENSPMAT00000009481.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 175.252 bits (443), Expect = 1.047e-47
Identity = 112/323 (34.67%), Postives = 170/323 (52.63%), Query Frame = 3

Query: 1275 NSNRVYVTRRLVLKDVIQNPDYISLA---INSKLEIPRNHVKVSGVKLGEGNFGTVFLG-------SVDSRDVAIKIPTEQG----QDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP-LINHPCQEIN-LNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESVNYYEYV*FTF 2189
            N N   V   ++   V  NP+Y S A   I  + E+ R+ VK+   +LG+G FG V+ G         D   VAIK   E      +    +E  +M+    H HV+ L+G+      +  IMEL + G LK+YL+S  P     P +  + L ++     +I  GM YL++K  VHRDLA RN ++AE+  +KI DFG+TR +   +YY    +   P RWM+PE   +  FT  SDVWS+G+VLWEI T    PY  LS  +V   + +G +   P   P  + +L++KCW+++  +RPTF +I++ L    +  +  F+F
Sbjct:   23 NRNEAAVPNGVLYASV--NPEYFSTADVYIADEWEVERDKVKMM-RELGQGTFGMVYEGLARGIVKGEDETRVAIKTVNETATMRERYEFLNEASVMKSFNCH-HVVRLLGVVSQAQPILVIMELMTRGDLKSYLRSLRPDAEKKPTRPPSSLPEMLQMAGEIADGMAYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATQAEQPYQGLSNEQVLKFVMDGGLLVLPPACPERLQELIRKCWQYNPRMRPTFLEILDGLAPDLHPSFHEFSF 341

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BLAST of FGFR1 vs. Ensembl Yeast
Match: STE11 (Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354])

HSP 1 Score: 94.3597 bits (233), Expect = 2.191e-20
Identity = 83/328 (25.30%), Postives = 148/328 (45.12%), Query Frame = 3

Query: 1326 QNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLG------------SVDSRDVAIKIPTEQGQ-------------------------------------DMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESR---PFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVY----DLMKKCWRFDEDLRPTFADIV 2141
            ++ D +SL   +K+  P+N +K  G  +G G+FG+V+LG             V+ ++  I +PT+  +                                     D L  E+ +++++  H +++   G   + G+L   +E   GGS+ + L +  P       E +L  +  +T QI  G+ YL  K+I+HRD+   NIL+   G +KI DFG+++ +       ++ +       WM+PE   +   TAK+D+WS G V+ E+FT G  P+   S  +   AI     N  PE+ P W      + ++K +  D   RP+  +++
Sbjct:  398 EDSDIVSLP--TKIATPKNWLK--GACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKEL-HHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPF------EESL--ITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT-GKHPFPDFSQMQ---AIFKIGTNTTPEI-PSWATSEGKNFLRKAFELDYQYRPSALELL 707

[Close]

BLAST of FGFR1 vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999])

HSP 1 Score: 89.7373 bits (221), Expect = 6.765e-19
Identity = 59/204 (28.92%), Postives = 100/204 (49.02%), Query Frame = 3

Query: 1401 VKLGEGNFGTVFLGSVDSRDVAIKIP-----TEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGL-TRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYF 1994
            VK+G+G  G V+       +V++ I       +  ++++ +E+ +M+   +H +++  I     +G LW IME   GGSL + +  C          +   Q+     +   G+ +L SK ++HRD+ + NILL+  GDIK+ DFG   +I        +    P+ WMAPE      +  K D+WS GI++ E+   G  PY 
Sbjct:  624 VKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKG-SKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHC---------ILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPY-WMAPEVVSRKEYGPKVDIWSLGIMIIEMIE-GEPPYL 815

[Close]

BLAST of FGFR1 vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 87.0409 bits (214), Expect = 4.781e-18
Identity = 66/245 (26.94%), Postives = 117/245 (47.76%), Query Frame = 3

Query: 1407 LGEGNFGTVFLGSVDSRD--VAIKIPTEQGQDMLFD---EVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPT 2126
            +G G++G V+       D  VAIK    +  + L D   E+ +++ +  H ++++  G       L+ ++E  + GSL+        LI+     ++ N+  TY  Q   G+ YL  + ++HRD+   NILL+ +  +K+ADFG++ IV +   +++       WMAPE       +  SD+WS G  + E+ T    PY +L+   +  A+ N      P      + D + KC+  +   RPT
Sbjct:   31 IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLN-HNNIVKYHGFIRKSYELYILLEYCANGSLRR-------LISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGT---LNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNP-PYHNLTDANIYYAVENDTYY-PPSSFSEPLKDFLSKCFVKNMYKRPT 262

[Close]

BLAST of FGFR1 vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 84.3445 bits (207), Expect = 7.736e-18
Identity = 71/259 (27.41%), Postives = 118/259 (45.56%), Query Frame = 3

Query: 1407 LGEGNFGTVFL--GSVDSRDVAIK------IPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            LG G+FG V L   + + R  A+K      I   +  +   DE RM+  I  H  ++ + G   D   ++ +M+   GG L + L+      N P  +        Y  ++   + YL SK I++RDL   NILL +NG IKI DFG  + V +  +++        ++APE      +    D WS+G++++E+   G  P+++ +  +  + I N  +   P   P    DL+KK      DL     ++ N  E V
Sbjct:   94 LGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLS-IVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPN-PVAKF-------YAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTP---DYIAPEVVSTKPYNKSVDWWSFGVLIYEMLA-GYTPFYNSNTMKTYENILNAELKFPPFFHPD-AQDLLKKL--ITRDLSERLGNLQNGSEDV 336

[Close]

BLAST of FGFR1 vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 84.7297 bits (208), Expect = 3.032e-17
Identity = 78/294 (26.53%), Postives = 137/294 (46.60%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFL--GSVDSRDVAIK---IPTEQGQ--------DMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGS----LKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHS--MSEESRPFRWMAPECF-VENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLS-----FNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQ 2147
            I+ A NSK E  +    + G  +G+G+FG V+L         +A+K   +P    Q        + L  EV  ++ +  H ++++ +G           +E  +GGS    ++ Y +   PLI H             T Q+ KG+ YL SK I+HRD+   N+LL ++G  KI+DFG++R   + Y +  M+     F WMAPE    +  ++AK D+WS G ++ E+F  G  P+ +L      F   +      +  D   +  +   + +  C+  + + RPT  ++++ 
Sbjct: 1160 INKAKNSKGEY-KEFAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLD-HLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKH------------LTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVF-WMAPEMVDTKQGYSAKVDIWSLGCIVLEMFA-GKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSH 1437

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BLAST of FGFR1 vs. Ensembl Nematostella
Match: EDO49191 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHA4])

HSP 1 Score: 197.208 bits (500), Expect = 3.417e-54
Identity = 106/292 (36.30%), Postives = 175/292 (59.93%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVF------LGSVDSR-DVAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQS-------CNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLES 2156
            I L ++ + E+ R+ + + G+ LGEG FG V       L ++  R +VA+K+  E   +     L  E+ +M+ IG+H +++ LIG C  +G L+ ++E AS G+L+ +L++        NPL   P +++ L  L +++ Q+ +GM YL SK  +HRDLA RN+L+++N  IKIADFGL R +  I+YY   ++   P +WMA E   +  +TA+SDVW+YGI++WEI T G  PY  +   ++ + +  G   ++P      VY LM +CW  + + RPTFA+IV ++++
Sbjct:  308 IELPLDEEWELDRSQISLLGI-LGEGAFGRVVKADAIGLPNMPYRCNVAVKMLKEDATEHELADLVSEMEVMKTIGQHVNIINLIGACTQKGPLFVVVEYASQGNLRQFLRARRPIPEYANPLTEPPREKLKLVDLVSFSYQVARGMEYLESKKCIHRDLAARNVLVSDNHVIKIADFGLARDIHDIDYYRKTTDGRLPVKWMALEALFDRVYTAQSDVWAYGILMWEIVTFGGSPYPGIPLWKLFELLKEGYRMEQPVNCQDDVYALMLRCWHENPNQRPTFAEIVKEMDA 598

[Close]

BLAST of FGFR1 vs. Ensembl Nematostella
Match: EDO49126 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGW8])

HSP 1 Score: 184.882 bits (468), Expect = 1.848e-52
Identity = 105/278 (37.77%), Postives = 152/278 (54.68%), Query Frame = 3

Query: 1398 GVKLGEGNFGTV-------FLGSVDSRD--VAIK----IPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLIN--------HPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVI--NYYHSMSEESR-PFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            G  +G G FG V         G  ++++  VA+K    + T + +     E+ MM+Q+G+H +++ ++G     G L  I E    G L+NYL++    ++         P +E+  N L ++  QI  GM YLS K  VHRDLA RNIL+ E+  +KI+DFGLTR V   + YH M    + P +WMAPE   +N  T KSDVW++G+VLWEI TLG  PY   S  E    + NG   +KP+M    +Y +M+ CW    + RPTF  + NQLE +
Sbjct:   21 GEVVGSGAFGKVTKATIVGLPGGPENKETVVAVKKLNAMATMEDRRNFLSEIEMMKQLGKHLNIVSILGCVTHAGQLCLITEYCPYGDLRNYLRAIRDKVSTRDSLAGRAPGRELTQNDLLSFARQIAVGMEYLSQKMFVHRDLAARNILICEDNLVKISDFGLTRDVYESSEYHKMHNTGKLPLKWMAPEAIFQNVHTTKSDVWAFGVVLWEIVTLGGSPYPGQSGKEFYKKLKNGYRMEKPDMCSPELYAMMRSCWASSPEDRPTFTKLRNQLEQL 298

[Close]

BLAST of FGFR1 vs. Ensembl Nematostella
Match: EDO47097 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN91])

HSP 1 Score: 182.956 bits (463), Expect = 3.740e-52
Identity = 104/295 (35.25%), Postives = 157/295 (53.22%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSV------DSRDVAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFD--EGSLWAIMELASGGSLKNYLQ--------SCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESR--PFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            + L  N++ E PR+ +K+  + +G G FG VFL             VA K   E   D     L  E++++  IG H++++ L+G C    E  L  I+E    G+L N+L+        + +P    P +   L  L   + Q+ + M +L+S+  VHRDLA RN+L+ EN  +KIADFGL R +    H +   +   P +WMA E  V+  +T  SDVWS+G++LWEIFTLG  PY  L  NEV   +  G    +PE  P+ +YDLM +CW+ D   RPTF  ++  ++ +
Sbjct:    1 MKLPWNAEWEFPRDRIKLLDI-VGTGAFGQVFLAEAVGISNKQVTRVACKGLKENATDSEYRDLLSELKILMHIGEHKNIVNLLGACTKGRECDLLVIIEYCPHGNLLNFLRKRRDVFEATWSPPTEKPDETFTLTDLVITSFQVSRAMQFLASRRCVHRDLAARNVLVGENYVMKIADFGLARDIYKEEHYVKTTAGLLPVKWMAIEALVDQVYTHSSDVWSFGVLLWEIFTLGGSPYPGLPANEVYQYLMEGQRMAQPEDCPQEMYDLMLRCWQHDPAQRPTFTQLLETIDKI 294

[Close]

BLAST of FGFR1 vs. Ensembl Nematostella
Match: EDO49315 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHA0])

HSP 1 Score: 183.341 bits (464), Expect = 8.708e-52
Identity = 99/291 (34.02%), Postives = 163/291 (56.01%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTV-------FLGSVDSRDVAIKIPTEQGQDM-LFD---EVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL-----INHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            + +  + + E  R ++ +  V LGEG FG V         G+     VA+K+  E   +  LFD   E+ +M+ IG+H +++ L+G C   G L+ ++E A  G+L+ +L+   P+     +  P + + L  L T+  QI KGM YL+S+  +HRDLA RNIL+A++  +KIADFGL R V  ++YY   ++   P +WMA E   +  +T +SDVWS+GIV+WEI T G  PY  +   ++   +  G   ++P    + +Y++M+ CW  + + RPTF  +V   + +
Sbjct:   44 VEIEYDEEWEFDRTYLVIREV-LGEGAFGKVMRAEAFGLHGNSACTTVAVKMLKEDATEQELFDLVSEMEVMKSIGKHINIINLLGTCTQHGPLFVLVEYARWGNLRQFLRDRRPVKDYDDVMEPAETLTLLNLMTFCYQIAKGMEYLASRKCIHRDLAARNILVADDNILKIADFGLARDVHNVDYYRKTTDGRLPVKWMAFEALFDRVYTTQSDVWSFGIVVWEIITFGGTPYPGVPIEKLCMLLNTGYRMERPVNCSKELYEIMRNCWNENPEARPTFTSLVQAFDDL 333

[Close]

BLAST of FGFR1 vs. Ensembl Nematostella
Match: EDO47652 (Tyrosine-protein kinase receptor [Source:UniProtKB/TrEMBL;Acc:A7RLS3])

HSP 1 Score: 177.178 bits (448), Expect = 5.077e-50
Identity = 101/288 (35.07%), Postives = 152/288 (52.78%), Query Frame = 3

Query: 1338 YISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSR-------DVAIKIPTEQGQDMLFDEVRMMQQIGRHR-----HVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEI--NLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLE 2153
            + S+ I  + E+PR  +K+   +LG G+FG V+ G             VA+K  +E     + D +  +Q+    +     HV+ L+G+  D      +MEL   G LKN+L+S  P +     E    L Q+     +I  GM YL+++  VHRDLA RN ++  N  +KI DFG+TR +   +YY    +   P RWMAPE   +  FT+ SDVWS+G+V+WE+ TL   PY   S  EV   + +G +  KP+  P  ++DLM  CW+F    RPTF  I++ +E
Sbjct:    2 FPSVYIADEWEVPREKIKLIR-ELGNGSFGMVYEGEATDIVPNKPKCKVAVKTVSENAS--IRDRIEFLQEASIMKAFQCNHVVRLLGVVSDGQPTLVVMELMDNGDLKNFLRSHRPEVTMESDEPPPTLQQMLQMAGEIADGMAYLAARKFVHRDLAARNCMVNANLTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTSPSDVWSFGVVMWEMATLASQPYPGKSNEEVLKYVVDGGVMPKPDDCPDRLFDLMTLCWQFSPKARPTFLSIISLIE 286

[Close]

BLAST of FGFR1 vs. Ensembl Medaka
Match: fgfr1 (fibroblast growth factor receptor 1 [Source:NCBI gene;Acc:100125448])

HSP 1 Score: 200.29 bits (508), Expect = 9.510e-54
Identity = 109/292 (37.33%), Postives = 164/292 (56.16%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPC--------QEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLE 2153
            L  + + E+PR+ + V G  LGEG FG V +G V   D         VA+K+     TE+    L  E+ MM+ IG+H++++ L+G C  +G L+ I+E AS G+L+ YL++  P     C        + +++  L +   Q+ +GM YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M+ CW      RPTF  +V  L+
Sbjct:  476 LPQDPRWEVPRDKL-VLGKPLGEGCFGQVMMGEVLGLDKEKPNRVTNVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPDQVSVETMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDLD 766

[Close]

BLAST of FGFR1 vs. Ensembl Medaka
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:100049424])

HSP 1 Score: 194.897 bits (494), Expect = 1.817e-52
Identity = 105/296 (35.47%), Postives = 160/296 (54.05%), Query Frame = 3

Query: 1341 ISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            + L  + K E PR  + + G  LGEG FG V +      D         VA K+  +   D     L  E+ MM+ IG+H++++ L+G C  +G L+ ++E AS G+L+ YL++  P            P +++    L +   Q+ +GM YL+S+  +HRDLA RN+L+ ++  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWSYG++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M++CW      RPTF  +V  L+ +
Sbjct:  334 LELPSDPKWEFPRTRLTL-GKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAAKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEFASKGNLREYLRARRPPGMDYSFDTCKIPDEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDLDRI 628

[Close]

BLAST of FGFR1 vs. Ensembl Medaka
Match: ENSORLT00000000391.2 (fibroblast growth factor receptor 1-A [Source:NCBI gene;Acc:101155126])

HSP 1 Score: 194.126 bits (492), Expect = 3.332e-52
Identity = 105/292 (35.96%), Postives = 163/292 (55.82%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL-------INHPC-QEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLE 2153
            L  +   E+PR+ + + G  LGEG FG V L      D         VA+K+     +E+    L  E+ MM+ IG+H++++ L+G C  EG L+ ++E AS G+L+ YL++  P+          P    + + +L +   Q+ +GM+YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   +KP    + +Y +M+ CW      RPTF  +V  L+
Sbjct:  377 LPYDPAWELPRDRLTL-GKPLGEGCFGQVVLAEAVGLDRSKPARLTKVAVKMLKADASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQEGPLYVVVEYASKGNLREYLRARRPVGGEYWSGARQPLLGGVEIRELVSAAYQVARGMSYLASKKCIHRDLAARNVLVTEDDVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMEKPSACTQELYLMMRDCWHAVPSRRPTFQQLVEDLD 667

[Close]

BLAST of FGFR1 vs. Ensembl Medaka
Match: ENSORLT00000040527.1 (fibroblast growth factor receptor 1-A [Source:NCBI gene;Acc:101155126])

HSP 1 Score: 194.512 bits (493), Expect = 4.068e-52
Identity = 105/292 (35.96%), Postives = 163/292 (55.82%), Query Frame = 3

Query: 1347 LAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKI----PTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPL-------INHPC-QEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLE 2153
            L  +   E+PR+ + + G  LGEG FG V L      D         VA+K+     +E+    L  E+ MM+ IG+H++++ L+G C  EG L+ ++E AS G+L+ YL++  P+          P    + + +L +   Q+ +GM+YL+SK  +HRDLA RN+L+ E+  +KIADFGL R +  I+YY   +    P +WMAPE   +  +T +SDVWS+G++LWEIFTLG  PY  +   E+   +  G   +KP    + +Y +M+ CW      RPTF  +V  L+
Sbjct:  377 LPYDPAWELPRDRLTL-GKPLGEGCFGQVVLAEAVGLDRSKPARLTKVAVKMLKADASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQEGPLYVVVEYASKGNLREYLRARRPVGGEYWSGARQPLLGGVEIRELVSAAYQVARGMSYLASKKCIHRDLAARNVLVTEDDVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMEKPSACTQELYLMMRDCWHAVPSRRPTFQQLVEDLD 667

[Close]

BLAST of FGFR1 vs. Ensembl Medaka
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:100049424])

HSP 1 Score: 195.282 bits (495), Expect = 5.213e-52
Identity = 155/530 (29.25%), Postives = 239/530 (45.09%), Query Frame = 3

Query:  819 YTCAIG---GQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEI--------------ILNTSVGRVEMV---LKFADST--DTGIYLCRR----------------ESISERMMH-------LTVIPCIIYTMLNXXXXXXXXXXXXXXXXXXXXXSKRLRRAFQLK------------NSNRVYV-TRRLVLKD--VIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRD---------VAIKIPTEQGQDM----LFDEVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNP--------LINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIV--INYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            YTC +    G +++T+Q+DV   + R       +     N T+  G    F+C    YSD    +    H E+              IL ++V R  +    LK  + T  D G Y CR                 ES+S   +        + V  C+++ +L   I     +             ++L + F LK            NSN   V   RL   D  ++ N   + L  + K E PR  + + G  LGEG FG V +      D         VA K+  +   D     L  E+ MM+ IG+H++++ L+G C  +G L+ ++E AS G+L+ YL++  P            P +++    L +   Q+ +GM YL+S+  +HRDLA RN+L+ ++  +KIADFGL R V  I+YY   +    P +WMAPE   +  +T +SDVWSYG++LWEIFTLG  PY  +   E+   +  G   DKP      +Y +M++CW      RPTF  +V  L+ +
Sbjct:  238 YTCVVQNKYGTISQTYQLDV---LERSPHRPILQAGLPANQTVFVGNDVEFHCKV--YSDAQPHIQWLKHIEVNGTRYGPDGVPYVNILKSNVSRQTVTHSKLKLFNVTEKDEGKYWCRASNFVGKSEKAFWLEVTESVSNPKLEDEYADILIYVTGCVLF-ILAVVIVILCRMRMTTQKTVPAPPVQKLSK-FPLKRQQVSLDSNSSMNSNTPLVRIARLSSSDGPMLANVLELELPSDPKWEFPRTRLTL-GKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAAKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEFASKGNLREYLRARRPPGMDYSFDTCKIPDEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDLDRI 759

[Close]

BLAST of FGFR1 vs. Planmine SMEST
Match: SMESG000036590.1 (SMESG000036590.1)

HSP 1 Score: 983.015 bits (2540), Expect = 0.000e+0
Identity = 498/504 (98.81%), Postives = 501/504 (99.40%), Query Frame = 3

Query:   69 HFYWFIFIVEIVNGMFDFPSTDSCYEIRTFESKLSKLEYQTARLSCHINVIKRCRKGSVRWAWFKDNIQIKNGTRKKTRSQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNRDRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISERMMHLTVIPCIIYTMLNXXXXXXXXXXXXXXXXXXXXXSKRLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDE 1580
            HFYWFIFIVEIVNGMFDF STDSCYEIRTFESK+SKLEYQTARLSCHINVIK+CRKGSVRWAWFKDNIQIKNGT+KKTR QIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNR RRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISERMMHLTVIPCIIYTMLNFAIPFFIMIIAFILLFGIFVISKRLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDE
Sbjct:    6 HFYWFIFIVEIVNGMFDFLSTDSCYEIRTFESKISKLEYQTARLSCHINVIKKCRKGSVRWAWFKDNIQIKNGTQKKTRFQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNRYRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISERMMHLTVIPCIIYTMLNFAIPFFIMIIAFILLFGIFVISKRLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDE 509

[Close]

BLAST of FGFR1 vs. Planmine SMEST
Match: SMESG000036590.1 (SMESG000036590.1)

HSP 1 Score: 981.474 bits (2536), Expect = 0.000e+0
Identity = 500/511 (97.85%), Postives = 505/511 (98.83%), Query Frame = 3

Query:   57 FNSSHFYWFIFIVEIVNGMFDFPSTDSCYEIRTFESKLSKLEYQTARLSCHINVIKRCRKGSVRWAWFKDNIQIKNGTRKKTRSQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNRDRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISERMMHLTVIPCIIYTMLNXXXXXXXXXXXXXXXXXXXXXSKRLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGSL 1589
            F   HFYWFIFIVEIVNGMFDF STDSCYEIRTFESK+SKLEYQTARLSCHINVIK+CRKGSVRWAWFKDNIQIKNGT+KKTR QIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNR RRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISERMMHLTVIPCIIYTMLNFAIPFFIMIIAFILLFGIFVISKRLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEG++
Sbjct:    2 FLLGHFYWFIFIVEIVNGMFDFLSTDSCYEIRTFESKISKLEYQTARLSCHINVIKKCRKGSVRWAWFKDNIQIKNGTQKKTRFQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNRYRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISERMMHLTVIPCIIYTMLNFAIPFFIMIIAFILLFGIFVISKRLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDEGNI 512

[Close]

BLAST of FGFR1 vs. Planmine SMEST
Match: SMESG000036590.1 (SMESG000036590.1)

HSP 1 Score: 952.199 bits (2460), Expect = 0.000e+0
Identity = 484/490 (98.78%), Postives = 487/490 (99.39%), Query Frame = 3

Query:  111 MFDFPSTDSCYEIRTFESKLSKLEYQTARLSCHINVIKRCRKGSVRWAWFKDNIQIKNGTRKKTRSQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNRDRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISERMMHLTVIPCIIYTMLNXXXXXXXXXXXXXXXXXXXXXSKRLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDE 1580
            MFDF STDSCYEIRTFESK+SKLEYQTARLSCHINVIK+CRKGSVRWAWFKDNIQIKNGT+KKTR QIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNR RRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISERMMHLTVIPCIIYTMLNFAIPFFIMIIAFILLFGIFVISKRLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDE
Sbjct:    1 MFDFLSTDSCYEIRTFESKISKLEYQTARLSCHINVIKKCRKGSVRWAWFKDNIQIKNGTQKKTRFQIYIEHLIYNTTMSDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEKRTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGHVNNRYRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINPYSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAGQKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGIYLCRRESISERMMHLTVIPCIIYTMLNFAIPFFIMIIAFILLFGIFVISKRLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVSGVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRHVLELIGLCFDE 490

[Close]

BLAST of FGFR1 vs. Planmine SMEST
Match: SMESG000036598.1 (SMESG000036598.1)

HSP 1 Score: 409.068 bits (1050), Expect = 1.132e-139
Identity = 193/193 (100.00%), Postives = 193/193 (100.00%), Query Frame = 3

Query: 1599 MELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESVNYYEYV 2177
            MELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESVNYYEYV
Sbjct:    1 MELASGGSLKNYLQSCNPLINHPCQEINLNQLFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESVNYYEYV 193

[Close]

BLAST of FGFR1 vs. Planmine SMEST
Match: SMESG000054557.1 (SMESG000054557.1)

HSP 1 Score: 230.335 bits (586), Expect = 2.089e-64
Identity = 120/278 (43.17%), Postives = 173/278 (62.23%), Query Frame = 3

Query: 1368 EIPRNHVKVSGVKLGEGNFGTVFLG---SVDSRDVAIKIPTEQGQDMLFD--------EVRMMQQIGRHRHVLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEI-NLNQ--LFTYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINYYHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFSLSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQLESV 2159
            E PR+ +K++  KLGEG FG V+ G    +  +    K+  +  +D   D        E+ +M+ IGRH +V++L+GLC   G L  I+ELA  G+L+++++S N   +   + I NL    L TY+ QI  GM YL+S+S+VHRDL+ RNIL+ E+ ++KIADFGLTRIV  YY   ++   P +WMAPE  +E ++T KSDVWSYGI+LWEIFTLG  PY S+   +V D I  G  N +PE++   +Y LM+ CW    + RP F +IV  L+ +
Sbjct:  515 EFPRDKLKITNKKLGEGAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENLTASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVVDVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETLQDI 792

The following BLAST results are available for this feature:

BLAST of FGFR1 vs. Ensembl Human
BLAST of FGFR1 vs. Ensembl Celegans
BLAST of FGFR1 vs. Ensembl Fly
BLAST of FGFR1 vs. Ensembl Zebrafish
BLAST of FGFR1 vs. Ensembl Xenopus
BLAST of FGFR1 vs. Ensembl Mouse
BLAST of FGFR1 vs. UniProt/SwissProt
BLAST of FGFR1 vs. TrEMBL
BLAST of FGFR1 vs. Ensembl Cavefish
BLAST of FGFR1 vs. Ensembl Sea Lamprey
BLAST of FGFR1 vs. Ensembl Yeast
BLAST of FGFR1 vs. Ensembl Nematostella
BLAST of FGFR1 vs. Ensembl Medaka
BLAST of FGFR1 vs. Planmine SMEST

BLAST of FGFR1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
FGFR2	2.144e-54	36.73	fibroblast growth factor receptor 2 [Source:HGNC S...	[more]
FGFR1	7.334e-54	37.07	fibroblast growth factor receptor 1 [Source:HGNC S...	[more]
FGFR1	7.477e-54	37.07	fibroblast growth factor receptor 1 [Source:HGNC S...	[more]
FGFR1	7.809e-54	37.07	fibroblast growth factor receptor 1 [Source:HGNC S...	[more]
FGFR2	9.992e-54	36.73	fibroblast growth factor receptor 2 [Source:HGNC S...	[more]

BLAST of FGFR1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
R151.1	2.396e-46	34.81	pep chromosome:WBcel235:III:7218813:7221186:1 gene...	[more]
csk-1	5.271e-46	34.17	Tyrosine-protein kinase csk-1 [Source:UniProtKB/S...	[more]
csk-1	5.271e-46	34.17	Tyrosine-protein kinase csk-1 [Source:UniProtKB/S...	[more]
csk-1	1.333e-45	34.17	Tyrosine-protein kinase csk-1 [Source:UniProtKB/S...	[more]
csk-1	1.333e-45	34.17	Tyrosine-protein kinase csk-1 [Source:UniProtKB/S...	[more]

BLAST of FGFR1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
htl	2.127e-52	37.59	gene:FBgn0010389 transcript:FBtr0083550	[more]
htl	2.127e-52	37.59	gene:FBgn0010389 transcript:FBtr0083549	[more]
htl	2.127e-52	37.59	gene:FBgn0010389 transcript:FBtr0083548	[more]
btl	1.532e-49	34.29	gene:FBgn0285896 transcript:FBtr0100676	[more]
btl	1.532e-49	34.29	gene:FBgn0285896 transcript:FBtr0075778	[more]

BLAST of FGFR1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fgfr3	1.161e-54	35.64	fibroblast growth factor receptor 3 [Source:NCBI g...	[more]
fgfr1b	5.250e-53	38.27	fibroblast growth factor receptor 1b [Source:ZFIN;...	[more]
fgfr1b	5.366e-53	38.27	fibroblast growth factor receptor 1b [Source:ZFIN;...	[more]
fgfr3	7.398e-52	34.53	fibroblast growth factor receptor 3 [Source:NCBI g...	[more]
fgfr3	7.849e-52	34.53	fibroblast growth factor receptor 3 [Source:NCBI g...	[more]

BLAST of FGFR1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fgfr4	4.410e-54	37.16	fibroblast growth factor receptor 4 [Source:NCBI g...	[more]
fgfr4	8.594e-54	37.16	fibroblast growth factor receptor 4 [Source:NCBI g...	[more]
fgfr4	8.613e-54	37.16	fibroblast growth factor receptor 4 [Source:NCBI g...	[more]
fgfr4	9.678e-54	37.16	fibroblast growth factor receptor 4 [Source:NCBI g...	[more]
fgfr4	1.063e-53	37.16	fibroblast growth factor receptor 4 [Source:NCBI g...	[more]

BLAST of FGFR1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Fgfr2	1.589e-54	36.73	fibroblast growth factor receptor 2 [Source:MGI Sy...	[more]
Fgfr2	1.776e-54	36.73	fibroblast growth factor receptor 2 [Source:MGI Sy...	[more]
Fgfr1	4.891e-54	37.07	fibroblast growth factor receptor 1 [Source:MGI Sy...	[more]
Fgfr1	4.891e-54	37.07	fibroblast growth factor receptor 1 [Source:MGI Sy...	[more]
Fgfr1	4.891e-54	37.07	fibroblast growth factor receptor 1 [Source:MGI Sy...	[more]

BLAST of FGFR1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8MY86\|FGFR1_DUGJA	2.245e-62	43.37	Fibroblast growth factor receptor 1 OS=Dugesia jap...	[more]
sp\|Q8MY85\|FGFR2_DUGJA	1.771e-57	41.16	Fibroblast growth factor receptor 2 OS=Dugesia jap...	[more]
sp\|Q91147\|FGFR2_NOTVI	6.856e-53	37.07	Fibroblast growth factor receptor 2 OS=Notophthalm...	[more]
sp\|P16092\|FGFR1_MOUSE	8.598e-53	37.07	Fibroblast growth factor receptor 1 OS=Mus musculu...	[more]
sp\|P11362\|FGFR1_HUMAN	9.547e-53	37.07	Fibroblast growth factor receptor 1 OS=Homo sapien...	[more]

BLAST of FGFR1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H9CXV7	2.612e-79	98.71	Receptor protein-tyrosine kinase OS=Schmidtea medi...	[more]
T1G069	2.224e-61	40.27	Protein kinase domain-containing protein OS=Helobd...	[more]
H9CXV6	1.004e-60	43.17	FGFR4 (Fragment) OS=Schmidtea mediterranea OX=7932...	[more]
A0A0R3UM39	4.849e-59	41.57	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A158RDD1	1.381e-56	39.73	Protein kinase domain-containing protein OS=Hydati...	[more]

BLAST of FGFR1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fgfr1a	3.935e-54	36.99	fibroblast growth factor receptor 1a [Source:NCBI ...	[more]
fgfr3	1.115e-52	35.33	fibroblast growth factor receptor 3 [Source:NCBI g...	[more]
fgfr3	1.250e-52	35.83	fibroblast growth factor receptor 3 [Source:NCBI g...	[more]
fgfr4	4.640e-51	35.47	fibroblast growth factor receptor 4 [Source:NCBI g...	[more]
fgfr2	5.380e-51	35.90	fibroblast growth factor receptor 2 [Source:NCBI g...	[more]

BLAST of FGFR1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fgfr2	5.827e-53	36.33	fibroblast growth factor receptor 2 [Source:NCBI g...	[more]
ENSPMAT00000006670.1	9.315e-51	36.96	pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene...	[more]
NTRK2	2.243e-50	35.60	neurotrophic receptor tyrosine kinase 2 [Source:HG...	[more]
ENSPMAT00000004129.1	3.637e-49	35.82	pep scaffold:Pmarinus_7.0:GL490249:304:4500:1 gene...	[more]
ENSPMAT00000009481.1	1.047e-47	34.67	pep scaffold:Pmarinus_7.0:GL477866:614:5163:1 gene...	[more]

BLAST of FGFR1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
STE11	2.191e-20	25.30	Signal transducing MEK kinase; involved in pheromo...	[more]
STE20	6.765e-19	28.92	Cdc42p-activated signal transducing kinase; involv...	[more]
CDC15	4.781e-18	26.94	Protein kinase of the Mitotic Exit Network; locali...	[more]
TPK3	7.736e-18	27.41	cAMP-dependent protein kinase catalytic subunit; p...	[more]
BCK1	3.032e-17	26.53	MAPKKK acting in the protein kinase C signaling pa...	[more]

BLAST of FGFR1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO49191	3.417e-54	36.30	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49126	1.848e-52	37.77	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47097	3.740e-52	35.25	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49315	8.708e-52	34.02	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47652	5.077e-50	35.07	Tyrosine-protein kinase receptor [Source:UniProtK...	[more]

BLAST of FGFR1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fgfr1	9.510e-54	37.33	fibroblast growth factor receptor 1 [Source:NCBI g...	[more]
fgfr3	1.817e-52	35.47	fibroblast growth factor receptor 3 [Source:NCBI g...	[more]
ENSORLT00000000391.2	3.332e-52	35.96	fibroblast growth factor receptor 1-A [Source:NCBI...	[more]
ENSORLT00000040527.1	4.068e-52	35.96	fibroblast growth factor receptor 1-A [Source:NCBI...	[more]
fgfr3	5.213e-52	29.25	fibroblast growth factor receptor 3 [Source:NCBI g...	[more]

BLAST of FGFR1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000036590.1	0.000e+0	98.81	SMESG000036590.1	[more]
SMESG000036590.1	0.000e+0	97.85	SMESG000036590.1	[more]
SMESG000036590.1	0.000e+0	98.78	SMESG000036590.1	[more]
SMESG000036598.1	1.132e-139	100.00	SMESG000036598.1	[more]
SMESG000054557.1	2.089e-64	43.17	SMESG000054557.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30034490
GenBank	AFD29628.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034490 ID=SMED30034490|Name=FGFR1|organism=Schmidtea mediterranea sexual|type=transcript|length=2276bp
ATTCAATAAATTTTTAGATATTTTTTGTGAATATAAAGTATTATGAAATG
ATTAAATTTAATTCCAGTCATTTTTATTGGTTTATTTTCATTGTCGAAAT
AGTTAATGGAATGTTCGATTTTCCATCAACAGATTCATGTTATGAAATTA
GAACATTTGAATCAAAACTTTCTAAGCTTGAATATCAAACAGCTAGACTA
TCTTGTCACATCAATGTTATAAAAAGGTGTCGGAAAGGATCTGTACGATG
GGCTTGGTTTAAAGATAATATTCAAATAAAAAATGGCACCCGGAAAAAAA
CTCGTTCTCAAATTTATATAGAGCATTTAATATATAATACAACAATGAGC
GATACTGGAGAATATCATTGTTTAGTGCAAAATAATGTCTTCAATTATAG
TCAATATGTAAATTTGTCAGTTTCAGTGGGAACTCCAGAATTGAAAGTCA
TCCGGTTAAATACAGTACCCCTAAACATTTCAGTGTTGGAAGAGAAGCGC
ACTTATTGGATGCCGAAAATGACAACTGAATTATACGAAATTAGTTATAA
GTTTGAGTTATCCAATACTTACAGACTTCAGTGTCAATTCTTTTCATTAG
CAAAGTTAAATATCAGCAGTGTCAGATGGTACGGTAGCTGGGGCCATGTA
AATAATAGAGATAGAAGAACTTTCGGAGAACTCATTAAAACCGGTTCCGA
GTATGAAATCAAAACAATTCCTTATAATTGTAATCAAGAAAAATTCTTGA
ATATCAAAAATGGAACTTGCTATGACAGTGATTTCAAGATAAATCCATAT
TCAAAGCTTTATAAATATTACACATGTGCCATTGGCGGTCAATTAAACAG
AACTCATCAAATTGATGTTAAGAATTACATTTTCAGACAAGTTGATCTTT
CTAATGAGAAATTACGTTTCACAGGAAATTCTACCATCTGTGCCGGACAA
AAGTTTATTTTTAATTGCTCAACAGAAAAATATTCTGATACAAATTTATT
TTTAATCAGAAAAAATCACAATGAAATTATATTAAATACTTCAGTTGGGA
GAGTTGAGATGGTTTTGAAATTTGCAGATTCGACTGATACTGGGATATAT
TTGTGCAGAAGGGAAAGTATTTCAGAAAGAATGATGCATTTAACTGTAAT
TCCCTGTATCATTTATACTATGTTGAATTTCGCAATACCATTTTTCATAA
TGATAATAGCATTTATATTGCTTTTTGGAATATTTGTAATCTCTAAACGC
CTTAGAAGGGCTTTTCAGTTAAAAAATTCAAACCGTGTATATGTTACGCG
TCGACTGGTTCTAAAAGATGTCATTCAGAATCCTGATTACATTTCCTTGG
CGATAAATTCAAAATTAGAAATTCCCAGAAATCATGTAAAGGTTTCTGGA
GTAAAATTGGGTGAAGGTAATTTTGGCACTGTTTTCCTTGGTTCGGTAGA
TTCCAGAGATGTTGCCATAAAAATTCCGACCGAACAGGGACAAGACATGC
TGTTTGATGAAGTACGAATGATGCAACAAATCGGTCGCCATCGGCACGTA
CTCGAGTTAATTGGACTCTGTTTTGATGAAGGTTCTCTTTGGGCTATAAT
GGAACTAGCGTCTGGAGGAAGCTTGAAAAATTACCTTCAGTCATGTAATC
CTTTAATAAATCATCCTTGTCAAGAAATAAATCTCAATCAACTTTTTACT
TATACCTTGCAAATCGGAAAAGGAATGAATTATTTGTCTTCGAAATCAAT
TGTCCACAGGGATTTGGCGACCCGTAATATCTTGCTAGCTGAAAATGGTG
ATATTAAAATAGCTGATTTCGGCTTGACGAGAATTGTCATAAATTACTAT
CACAGCATGTCAGAAGAGTCTCGACCGTTTCGGTGGATGGCACCAGAATG
CTTTGTTGAAAATAGATTTACAGCTAAAAGTGATGTTTGGTCTTATGGAA
TTGTGCTTTGGGAAATTTTCACATTAGGTGTCATTCCGTATTTTTCTCTG
TCGTTTAATGAAGTACGCGACGCAATTTGCAATGGCGTTATCAATGATAA
ACCAGAAATGTCACCAAGATGGGTTTATGATTTAATGAAGAAATGCTGGA
GGTTTGATGAGGATTTGAGACCAACATTTGCAGATATTGTCAACCAACTG
GAAAGTGTGAATTACTACGAATATGTTTAATTTACTTTTCTAATGTTAAT
ATTGTAAATTTTTGTATAATGTATTTTGTATATTACGTTTTGACGTTTTT
TTGGTCAATAAATAATGTTTTTTTTT

protein sequence of SMED30034490-orf-1

>SMED30034490-orf-1 ID=SMED30034490-orf-1|Name=SMED30034490-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=711bp
MIKFNSSHFYWFIFIVEIVNGMFDFPSTDSCYEIRTFESKLSKLEYQTAR
LSCHINVIKRCRKGSVRWAWFKDNIQIKNGTRKKTRSQIYIEHLIYNTTM
SDTGEYHCLVQNNVFNYSQYVNLSVSVGTPELKVIRLNTVPLNISVLEEK
RTYWMPKMTTELYEISYKFELSNTYRLQCQFFSLAKLNISSVRWYGSWGH
VNNRDRRTFGELIKTGSEYEIKTIPYNCNQEKFLNIKNGTCYDSDFKINP
YSKLYKYYTCAIGGQLNRTHQIDVKNYIFRQVDLSNEKLRFTGNSTICAG
QKFIFNCSTEKYSDTNLFLIRKNHNEIILNTSVGRVEMVLKFADSTDTGI
YLCRRESISERMMHLTVIPCIIYTMLNFAIPFFIMIIAFILLFGIFVISK
RLRRAFQLKNSNRVYVTRRLVLKDVIQNPDYISLAINSKLEIPRNHVKVS
GVKLGEGNFGTVFLGSVDSRDVAIKIPTEQGQDMLFDEVRMMQQIGRHRH
VLELIGLCFDEGSLWAIMELASGGSLKNYLQSCNPLINHPCQEINLNQLF
TYTLQIGKGMNYLSSKSIVHRDLATRNILLAENGDIKIADFGLTRIVINY
YHSMSEESRPFRWMAPECFVENRFTAKSDVWSYGIVLWEIFTLGVIPYFS
LSFNEVRDAICNGVINDKPEMSPRWVYDLMKKCWRFDEDLRPTFADIVNQ
LESVNYYEYV*

Aliases

The feature 'FGFR1' has the following synonyms


Synonym
FGFR1

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0006468	protein phosphorylation
GO:0016310	phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000016	pharynx
PLANA:0000429	neoblast
PLANA:0002032	epidermal cell
PLANA:0002075	pigment cell
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR036179	Ig-like_dom_sf
IPR001245	Ser-Thr/Tyr_kinase_cat_dom
IPR003599	Ig_sub
IPR020635	Tyr_kinase_cat_dom
IPR013783	Ig-like_fold
IPR013151	Immunoglobulin
IPR017441	Protein_kinase_ATP_BS
IPR008266	Tyr_kinase_AS
IPR000719	Prot_kinase_dom
IPR007110	Ig-like_dom
IPR011009	Kinase-like_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0005515	protein binding
GO:0000166	nucleotide binding
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PRINTS	PR00109	TYRKINASE	coord: 628..650 score: 60.48 coord: 609..619 score: 49.86 coord: 518..531 score: 40.13 coord: 562..580 score: 57.71 coord: 672..694 score: 41.45
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PFAM	PF07714	Pkinase_Tyr	coord: 452..701 e-value: 2.7E-77 score: 259.5
IPR003599	Immunoglobulin subtype	SMART	SM00409	IG_3c	coord: 292..368 e-value: 99.0 score: 2.8 coord: 38..126 e-value: 6.7E-5 score: 32.3
IPR020635	Tyrosine-protein kinase, catalytic domain	SMART	SM00219	tyrkin_6	coord: 448..701 e-value: 3.6E-98 score: 342.1
IPR013783	Immunoglobulin-like fold	GENE3D	G3DSA:2.60.40.10		coord: 36..130 e-value: 1.3E-8 score: 36.6
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 444..707 e-value: 2.6E-74 score: 251.6
None	No IPR available	PIRSF	PIRSF000615	TyrPK_CSF1-R	coord: 531..709 e-value: 4.1E-51 score: 171.8 coord: 428..540 e-value: 1.3E-6 score: 24.5 coord: 32..149 e-value: 0.081 score: 8.6 coord: 247..377 e-value: 12.0 score: 1.4
None	No IPR available	PANTHER	PTHR24418	TYROSINE-PROTEIN KINASE	coord: 271..703
None	No IPR available	CDD	cd00096	Ig	coord: 70..122 e-value: 2.03947E-5 score: 41.0737
None	No IPR available	CDD	cd00192	PTKc	coord: 453..702 e-value: 2.01811E-106 score: 322.566
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..21 score: 0.554
None	No IPR available	TMHMM	TMhelix		coord: 630..652
None	No IPR available	TMHMM	TMhelix		coord: 377..399
IPR013151	Immunoglobulin	PFAM	PF00047	ig	coord: 42..118 e-value: 5.0E-5 score: 23.4
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 454..475
IPR008266	Tyrosine-protein kinase, active site	PROSITE	PS00109	PROTEIN_KINASE_TYR	coord: 568..580
IPR007110	Immunoglobulin-like domain	PROSITE	PS50835	IG_LIKE	coord: 47..124 score: 8.629
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 448..710 score: 38.789
IPR036179	Immunoglobulin-like domain superfamily	SUPERFAMILY	SSF48726	Immunoglobulin	coord: 38..126
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 418..701