Potassium channel subfamily K member 18
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30034472 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK16 (potassium two pore domain channel subfamily K member 16 [Source:HGNC Symbol;Acc:HGNC:14464]) HSP 1 Score: 64.6994 bits (156), Expect = 3.954e-11 Identity = 47/153 (30.72%), Postives = 71/153 (46.41%), Query Frame = 3 Query: 54 IFSCAGS-----ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIG 497 + SC G +L V Y L+G +F+L+E Q E + + + + R +E NY LD + F+ E K N N T N +W S F+ TV+TTIGYG P T G+ + YA++GIP + L+++G Sbjct: 6 LCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLE---NYT--------CLDQWAMEQFVQVIMEAWVKGVNPKGNST---NPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLG 144
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK16 (potassium two pore domain channel subfamily K member 16 [Source:HGNC Symbol;Acc:HGNC:14464]) HSP 1 Score: 65.0846 bits (157), Expect = 4.604e-11 Identity = 47/151 (31.13%), Postives = 70/151 (46.36%), Query Frame = 3 Query: 60 SCAGS-----ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIG 497 SC G +L V Y L+G +F+L+E Q E + + + + R +E NY LD + F+ E K N N T N +W S F+ TV+TTIGYG P T G+ + YA++GIP + L+++G Sbjct: 8 SCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLE---NYT--------CLDQWAMEQFVQVIMEAWVKGVNPKGNST---NPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLG 144
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK16 (potassium two pore domain channel subfamily K member 16 [Source:HGNC Symbol;Acc:HGNC:14464]) HSP 1 Score: 64.6994 bits (156), Expect = 5.478e-11 Identity = 47/153 (30.72%), Postives = 71/153 (46.41%), Query Frame = 3 Query: 54 IFSCAGS-----ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIG 497 + SC G +L V Y L+G +F+L+E Q E + + + + R +E NY LD + F+ E K N N T N +W S F+ TV+TTIGYG P T G+ + YA++GIP + L+++G Sbjct: 6 LCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLE---NYT--------CLDQWAMEQFVQVIMEAWVKGVNPKGNST---NPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLG 144
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK18 (potassium two pore domain channel subfamily K member 18 [Source:HGNC Symbol;Acc:HGNC:19439]) HSP 1 Score: 65.0846 bits (157), Expect = 5.788e-11 Identity = 47/163 (28.83%), Postives = 75/163 (46.01%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKK 563 + +V Y L+G +F IE+ Q + ++ +E+L ILN + + +L L K+K + +N T W+ S+ F TV +T+GYG P TR GK+L ++YA+ GIP FL L++ G + Y RK F + Sbjct: 27 LCFLVTYALVGAVVFSAIEDGQ--VLVAADDGEFEKFLEELCR-ILNCSETVVEDRKQDLQG-------HLQKVKPQWFNRT-----THWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNRFRKFPFFTR 174
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK16 (potassium two pore domain channel subfamily K member 16 [Source:HGNC Symbol;Acc:HGNC:14464]) HSP 1 Score: 64.3142 bits (155), Expect = 5.903e-11 Identity = 47/153 (30.72%), Postives = 71/153 (46.41%), Query Frame = 3 Query: 54 IFSCAGS-----ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIG 497 + SC G +L V Y L+G +F+L+E Q E + + + + R +E NY LD + F+ E K N N T N +W S F+ TV+TTIGYG P T G+ + YA++GIP + L+++G Sbjct: 6 LCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLE---NYT--------CLDQWAMEQFVQVIMEAWVKGVNPKGNST---NPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLG 144
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-48 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q7YWY7]) HSP 1 Score: 127.102 bits (318), Expect = 7.840e-33 Identity = 116/395 (29.37%), Postives = 184/395 (46.58%), Query Frame = 3 Query: 33 LSRFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKN-------EGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLI--HIKRSLPKQQEKKLKKVSSKL-RYKRKHPKGERNLVNWNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKI-DSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYK 1184 + + F FS G ++V Y L+G +FK +E E I+ +K ++ V+ + N + + N LD +L +E+ + K +G++G + WT G+ L+SLTVITTIGYG KT GK LT++YAIIGIP L L+NIG +K F Y + KF RLI H KR + K+++ +S + R R H + V+ + + +V L R EQ E E + +PI++ ++ Y+ +G F +WE +L+ YFCFI+L+TIGFGD P T + ++D +EKL+ Y++ G+++ +MCF L +EE++ K Sbjct: 17 VKKIIAFFFSHIGLCALVVGYALLGAVIFKAVEGPHEAEIQELVKSAREKAVDVVWN---ATFRVN-RLDSKQWKKTVL---DEVKRFKTVCMLSIRKGYDGKEYGKQAQWTFTGAFLYSLTVITTIGYGNTAAKTYIGKTLTMLYAIIGIPLMLLFLTNIGDVMAKIFRFLYAQSIRLKF---------RLILWHKKR-----KAAKIRRANSLVSRLTRGHRVKADSSVDSFGLGA----------------------------------GADVEDLLTARVEMEQLEVRETAAAQLESMTVPISLVVFTMLGYLGVGTTIFKVWEGWTFLESFYFCFISLTTIGFGDKFPSTSVSNTDEAQEKLVITSIYLLFGMALLAMCFNLAQEEVQNK 356
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-39 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:A1EHR5]) HSP 1 Score: 93.5893 bits (231), Expect = 2.076e-20 Identity = 57/170 (33.53%), Postives = 92/170 (54.12%), Query Frame = 3 Query: 45 TKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYI--LNSLKENISLDPSNLNNFLLKYTEEL--SKLKNEGWNGTFGENE-YSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFL 539 T F + G ++ +Y + G FMF+ +E E ++ K+K S ++V+ + +I N ++E N + + LK E L + EG++ E + WT G++L+S+TV TTIGYG PKT G+ LTI+Y+I+GIP L L+NI + ++ F Y L Sbjct: 20 TIFTITHVGLCFLVALYAVAGAFMFQAVEYPYELGLQGKVKNASLKVVDDIYRFINRKNVIEETAV---KNESQWALKEFEMLLVHAMNFEGYDEHDEERPTFQWTFSGALLYSITVFTTIGYGHICPKTDTGRLLTILYSILGIPLMLLCLANIAETLAQVFTYIYFKL 186 HSP 2 Score: 70.4774 bits (171), Expect = 6.206e-13 Identity = 36/77 (46.75%), Postives = 55/77 (71.43%), Query Frame = 3 Query: 960 GALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYKWK 1190 GA F+ WE+ + AY+CFITLSTIGFGDIVPG +D + +EKL+ Y++ G+++ +MCFKLM++++ K + Sbjct: 508 GAWLFSWWENWNGFDGAYYCFITLSTIGFGDIVPGQALD-EGSQEKLVVCALYLLFGMALIAMCFKLMQDDVVQKAR 583
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-39 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:A1EHR5]) HSP 1 Score: 93.5893 bits (231), Expect = 2.293e-20 Identity = 57/170 (33.53%), Postives = 92/170 (54.12%), Query Frame = 3 Query: 45 TKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYI--LNSLKENISLDPSNLNNFLLKYTEEL--SKLKNEGWNGTFGENE-YSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFL 539 T F + G ++ +Y + G FMF+ +E E ++ K+K S ++V+ + +I N ++E N + + LK E L + EG++ E + WT G++L+S+TV TTIGYG PKT G+ LTI+Y+I+GIP L L+NI + ++ F Y L Sbjct: 20 TIFTITHVGLCFLVALYAVAGAFMFQAVEYPYELGLQGKVKNASLKVVDDIYRFINRKNVIEETAV---KNESQWALKEFEMLLVHAMNFEGYDEHDEERPTFQWTFSGALLYSITVFTTIGYGHICPKTDTGRLLTILYSILGIPLMLLCLANIAETLAQVFTYIYFKL 186 HSP 2 Score: 70.4774 bits (171), Expect = 6.444e-13 Identity = 36/77 (46.75%), Postives = 55/77 (71.43%), Query Frame = 3 Query: 960 GALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYKWK 1190 GA F+ WE+ + AY+CFITLSTIGFGDIVPG +D + +EKL+ Y++ G+++ +MCFKLM++++ K + Sbjct: 508 GAWLFSWWENWNGFDGAYYCFITLSTIGFGDIVPGQALD-EGSQEKLVVCALYLLFGMALIAMCFKLMQDDVVQKAR 583
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-18 (TWiK family of potassium channels protein 18 [Source:UniProtKB/Swiss-Prot;Acc:Q18120]) HSP 1 Score: 88.9669 bits (219), Expect = 4.207e-19 Identity = 63/201 (31.34%), Postives = 103/201 (51.24%), Query Frame = 3 Query: 12 LEIIKRGLSR-FTKFIFSCAG--SILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKN--EGWNGTFG------ENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFY--LFLRKSKFLKKQKEN 575 + I+ +G+S T F + G ++++V YTL+G ++F +IE + ER + ++ +K ++ + + Y +N L+ L+ EE ++ + T G + + WT GSI + +TV TTIGYG P T WG+F TI+YA IGIP T LSL +G F+K C FL+ ++ + K N Sbjct: 1 MAIVAQGVSTILTTFQKTFKGLLPLIILVAYTLLGAWIFWMIEGENEREMLIEQQKERDELIRR-TVYKINQLQ-------IKRQRRLMTAEEEYNRTAKVLTTFQETLGIVPADMDKDIHWTFLGSIFYCMTVYTTIGYGNIVPGTGWGRFATILYAFIGIPLTVLSLYCLGSLFAKG-CKMLWRFFLKSTRVVSKDLSN 192
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-18 (TWiK family of potassium channels protein 18 [Source:UniProtKB/Swiss-Prot;Acc:Q18120]) HSP 1 Score: 88.9669 bits (219), Expect = 4.207e-19 Identity = 63/201 (31.34%), Postives = 103/201 (51.24%), Query Frame = 3 Query: 12 LEIIKRGLSR-FTKFIFSCAG--SILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKN--EGWNGTFG------ENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFY--LFLRKSKFLKKQKEN 575 + I+ +G+S T F + G ++++V YTL+G ++F +IE + ER + ++ +K ++ + + Y +N L+ L+ EE ++ + T G + + WT GSI + +TV TTIGYG P T WG+F TI+YA IGIP T LSL +G F+K C FL+ ++ + K N Sbjct: 1 MAIVAQGVSTILTTFQKTFKGLLPLIILVAYTLLGAWIFWMIEGENEREMLIEQQKERDELIRR-TVYKINQLQ-------IKRQRRLMTAEEEYNRTAKVLTTFQETLGIVPADMDKDIHWTFLGSIFYCMTVYTTIGYGNIVPGTGWGRFATILYAFIGIPLTVLSLYCLGSLFAKG-CKMLWRFFLKSTRVVSKDLSN 192
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: sand (gene:FBgn0033257 transcript:FBtr0088780) HSP 1 Score: 100.523 bits (249), Expect = 3.705e-23 Identity = 67/179 (37.43%), Postives = 95/179 (53.07%), Query Frame = 3 Query: 9 SLEIIKRGLSRFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSL----KENISLDPSN-----LNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 + E K FT F+FS G IL++ Y + G F+F+ IE + R LK +K + I S L+ + ENIS + +N+ LL Y + K + +G + W+ G+ L+SLTVITTIGYG TP + GK +TI+YAIIG+P L LSNIG +K+F Sbjct: 15 AFERFKDHCRHFTAFMFSNVGIILLVTFYIIGGAFIFQSIEIFEYER--LKSEKPHRFIARNFSGECLSRIWELTAENISFFDHHAYRRRVNDVLLDYQRAIVKKQLKG------PDVEQWSFSGAFLYSLTVITTIGYGNITPHSECGKLVTILYAIIGMPLFLLYLSNIGDVLAKSF 185 HSP 2 Score: 68.5514 bits (166), Expect = 2.073e-12 Identity = 35/75 (46.67%), Postives = 52/75 (69.33%), Query Frame = 3 Query: 960 GALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKI---DSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEI 1175 GAL F WED +YL +YFC I+LS+IGFGD+VPG ++ D D + I Y+++G++V +MCF LM+E++ Sbjct: 301 GALLFGRWEDWNYLDGSYFCLISLSSIGFGDLVPGDRVITADRDKVEVSFILCAIYLLLGMAVIAMCFNLMQEQV 375
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: CG9194 (gene:FBgn0035192 transcript:FBtr0072651) HSP 1 Score: 92.4337 bits (228), Expect = 6.018e-20 Identity = 49/147 (33.33%), Postives = 85/147 (57.82%), Query Frame = 3 Query: 93 YTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNS----LKENISLDPSNLNNFLLKYTEE-LSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 Y + G ++F+ +E E +K ++ + E + ++L+ L+E+ + +N++ L + ++ L+ +K +GW+G + WT GS+ +S+ VITTIGYG +P+T WGK TI YAI+GIP + LSNIG + +F Sbjct: 51 YCVGGAYLFQHLERPHELEVKRDIQNLRVNLTENI--WLLSDDAVVLRESDWM--ANVSKHLANFEKQILTAIKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIGDVMATSF 193 HSP 2 Score: 56.225 bits (134), Expect = 3.218e-8 Identity = 30/71 (42.25%), Postives = 47/71 (66.20%), Query Frame = 3 Query: 960 GALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEE 1172 GA+ F WE+ +L AYFCFITL+TIGFGD VP + D ++ + + Y++ G+++ +M F L++EE Sbjct: 635 GAVLFAYWENWSFLDSAYFCFITLTTIGFGDFVPAKGV-KDESEQSIAYCSLYLLFGIALLAMSFNLVQEE 704
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: CG1688 (gene:FBgn0027589 transcript:FBtr0088495) HSP 1 Score: 84.7297 bits (208), Expect = 2.369e-17 Identity = 67/256 (26.17%), Postives = 115/256 (44.92%), Query Frame = 3 Query: 21 IKRGLSRFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKL--SNYILNSLKEN--ISLDPSNLNNF---LLKYTEELSK---------LKNEGWNGTFGENEY------SWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF-CGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSD 719 ++R K +FS G +L+++ Y+++GG +F L+E Q+ + K+ + + +L LN L E L L F ++ T + S L +EG G Y SW+ ++L+S+TVITTIG+G TP+T GK TI YA++G+P + LS++G + C ++R L++ +E H ++S P ++ R K + +R + N D Sbjct: 62 LRRCCGHLLKLLFSTPGLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELWIITEKLNVLYERNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAGDSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQC---TYVRLCCQLQRHQE------HRRKSTPGTSTPSASSAANS-REKDTDKRSKRRMANCKGCQYD 307 HSP 2 Score: 53.9138 bits (128), Expect = 1.658e-7 Identity = 29/77 (37.66%), Postives = 48/77 (62.34%), Query Frame = 3 Query: 960 GALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYKWK 1190 G + F +WE+ + AYFCF+TLSTIG+GD VP + P+ +L Y+++GL + +M F ++E ++ +K K Sbjct: 831 GTVIFALWENWSLVDGAYFCFVTLSTIGYGDFVPARSF--NGPELQLYACCAYLLLGLVLVAMSFSILETQLMWKCK 905
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: CG10864 (gene:FBgn0038621 transcript:FBtr0083654) HSP 1 Score: 82.0333 bits (201), Expect = 7.478e-17 Identity = 49/173 (28.32%), Postives = 86/173 (49.71%), Query Frame = 3 Query: 21 IKRGLSRFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVE---KLSNYILNSLKENISLD----PSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 +KR F F+ + G +IV+Y + G F F IE Q + +T+ ++E S + + +++ +D N+ L +Y +++ + G+ G E W+ +++F L+VIT IGYG P+T WGK T++YA GIP L N+G+ +++F Sbjct: 36 VKRCCRNFVTFMCTQVGVGALIVIYAICGAFAFMHIERQ-------FVDETAGHVMELRQNCSQQLWSITEQHNIIDRRRWTEATNDVLREYQSQIAGVVKHGYVGR--SPEQIWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIPLYILYFLNMGRVLARSF 199
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: CG34396 (gene:FBgn0085425 transcript:FBtr0112645) HSP 1 Score: 79.7221 bits (195), Expect = 9.846e-16 Identity = 52/162 (32.10%), Postives = 86/162 (53.09%), Query Frame = 3 Query: 63 CAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKEN-ISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRK 545 C ++ + + GG +F+ E E K +++K + +++L + N +E+ SL L +F +EL+ L G G+ SW +F TVITTIGYG TPKT G+ LTIVYAIIGIP + L+++G+ F++ ++++R+ Sbjct: 526 CIAYLICMAMLLGFGGLLFRYTEGAAENIYKCEVRKVKRDFIDRLWDVSHNMREEDWKSLARQKLRSF----EDELNNLAELGLRRYPGQK--SWNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRR 681
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Match: kcnk18 (potassium channel, subfamily K, member 18 [Source:ZFIN;Acc:ZDB-GENE-100405-2]) HSP 1 Score: 73.9442 bits (180), Expect = 5.906e-14 Identity = 47/161 (29.19%), Postives = 77/161 (47.83%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ----HFSKAFCGFYLFLRK 545 IL +V+Y ++G +F+ IE + R ++ Q+++E + N+ D S + + K + L E E ++ WT S+ F TV TT+GYG P T GK ++YA++GIP L +S++G SKA+ LF R+ Sbjct: 27 ILSLVLYAVLGALVFRAIEYKNPRNESEEILSIVQKVMEIVQNHT----------DTSEQKHLINKAKDILDDYCYEK------ERDHGWTFFASLFFCCTVFTTVGYGRIYPLTSKGKVACVLYAMVGIPLMLLVISDVGDLLAVLLSKAYTRLNLFFRR 171
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Match: kcnk18 (potassium channel, subfamily K, member 18 [Source:ZFIN;Acc:ZDB-GENE-100405-2]) HSP 1 Score: 71.633 bits (174), Expect = 2.961e-13 Identity = 47/161 (29.19%), Postives = 75/161 (46.58%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ----HFSKAFCGFYLFLRK 545 IL +V+Y ++G +F+ IE R ++ Q+++E + N+ D S + + K L E E ++ WT S+ F TV TT+GYG P T GK ++YA++GIP L +S++G SKA+ LF R+ Sbjct: 27 ILSLVLYAVLGALVFRAIEYTNPRNESEEILSIVQKVMEIVQNHT----------DASEQKHLINKAKYILDDYCYEK------ERDHGWTFFASLFFCCTVFTTVGYGRIYPLTSKGKVACVLYAMVGIPLMLLVISDVGDLLAVLLSKAYTRLNLFFRR 171
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Match: kcnk18 (potassium channel, subfamily K, member 18 [Source:ZFIN;Acc:ZDB-GENE-100405-2]) HSP 1 Score: 71.633 bits (174), Expect = 2.988e-13 Identity = 47/161 (29.19%), Postives = 75/161 (46.58%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ----HFSKAFCGFYLFLRK 545 IL +V+Y ++G +F+ IE R ++ Q+++E + N+ D S + + K L E E ++ WT S+ F TV TT+GYG P T GK ++YA++GIP L +S++G SKA+ LF R+ Sbjct: 27 ILSLVLYAVLGALVFRAIEYTNPRNESEEILSIVQKVMEIVQNHT----------DASEQKHLINKAKYILDDYCYEK------ERDHGWTFFASLFFCCTVFTTVGYGRIYPLTSKGKVACVLYAMVGIPLMLLVISDVGDLLAVLLSKAYTRLNLFFRR 171
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Match: kcnk1a (potassium channel, subfamily K, member 1a [Source:ZFIN;Acc:ZDB-GENE-070620-26]) HSP 1 Score: 67.781 bits (164), Expect = 4.632e-12 Identity = 41/146 (28.08%), Postives = 71/146 (48.63%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEE----LSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 +L V+Y + G +F +E E +++ +++ Q+ +E +N L L FL+K E +S L N N ++W ++ F+ TV++T GYG P + GK I+Y+++GIPFT L L+ + Q Sbjct: 27 VLAYVLYLIFGALVFSAVELPYEEQLRQELRTVKQQFLE-----------DNECLSNDRLEEFLIKALEASNYGVSVLNNASSN-------WNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVVGIPFTLLFLTAVVQ 154
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Match: kcnk1a (potassium channel, subfamily K, member 1a [Source:ZFIN;Acc:ZDB-GENE-070620-26]) HSP 1 Score: 67.781 bits (164), Expect = 4.632e-12 Identity = 41/146 (28.08%), Postives = 71/146 (48.63%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEE----LSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 +L V+Y + G +F +E E +++ +++ Q+ +E +N L L FL+K E +S L N N ++W ++ F+ TV++T GYG P + GK I+Y+++GIPFT L L+ + Q Sbjct: 27 VLAYVLYLIFGALVFSAVELPYEEQLRQELRTVKQQFLE-----------DNECLSNDRLEEFLIKALEASNYGVSVLNNASSN-------WNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVVGIPFTLLFLTAVVQ 154
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: kcnk6 (potassium channel, two pore domain subfamily K, member 6 [Source:NCBI gene;Acc:100145504]) HSP 1 Score: 70.0922 bits (170), Expect = 7.397e-13 Identity = 47/148 (31.76%), Postives = 74/148 (50.00%), Query Frame = 3 Query: 87 VVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEE----LSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 V+Y L+G + +IE+ E ++ ++++ L + LN E+ ++ S+L FL K +S L N N+ W + S+ F+ T++TT+GYG TP T GK I YA+IG+PFT L LS+ Q F Sbjct: 15 VIYLLLGALVISVIESPYEASLRDELRQ--------LKSVFLN---ESPCVNVSSLEAFLEKIINANKYGVSVLHN-------ASNDSKWDIASSMFFASTLVTTVGYGYTTPLTDSGKAFCIFYALIGVPFTMLVLSSFVQRLMVMF 144
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: kcnk6 (potassium channel, two pore domain subfamily K, member 6 [Source:NCBI gene;Acc:100145504]) HSP 1 Score: 70.0922 bits (170), Expect = 9.673e-13 Identity = 47/148 (31.76%), Postives = 74/148 (50.00%), Query Frame = 3 Query: 87 VVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEE----LSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 V+Y L+G + +IE+ E ++ ++++ L + LN E+ ++ S+L FL K +S L N N+ W + S+ F+ T++TT+GYG TP T GK I YA+IG+PFT L LS+ Q F Sbjct: 33 VIYLLLGALVISVIESPYEASLRDELRQ--------LKSVFLN---ESPCVNVSSLEAFLEKIINANKYGVSVLHN-------ASNDSKWDIASSMFFASTLVTTVGYGYTTPLTDSGKAFCIFYALIGVPFTMLVLSSFVQRLMVMF 162
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: bcdin3d (BCDIN3 domain containing RNA methyltransfease [Source:Xenbase;Acc:XB-GENE-5859380]) HSP 1 Score: 62.3882 bits (150), Expect = 2.459e-10 Identity = 36/146 (24.66%), Postives = 68/146 (46.58%), Query Frame = 3 Query: 78 LMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKA 515 + +VY L+G +F+++E + E K ++ + L+ LK L L++ + + + K + +W + S F+ TV+TTIGYG +P+T G+ ++YA+ GIP + L +G+ S+ Sbjct: 14 MAFMVYLLVGALVFQVLEKEAEDTAKTDTER-----------HRLDFLKNYTCLTKEALDHLVNQVITDAVKQGIHPLENQTKNSHSNWDMSSSFFFAGTVVTTIGYGTLSPRTPGGQIFCVLYALFGIPLNVIVLGRVGKILSRV 148
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: stk26 (serine/threonine kinase 26 [Source:Xenbase;Acc:XB-GENE-982067]) HSP 1 Score: 61.2326 bits (147), Expect = 6.246e-10 Identity = 49/156 (31.41%), Postives = 67/156 (42.95%), Query Frame = 3 Query: 54 IFSCAGSILMIV-------VYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 IF C I + V +Y +G MF+++E Q E + + + R L NY LD + L F+ E K N N T N +W S F+ TVITTIGYG P T G+ + YA+ GIP L+ IG+ Sbjct: 4 IFQCRRQISLSVALSLGYFLYLFLGAMMFQILEKQAESNTRDQFQVAKLRF---LQNYT--------CLDVNALEQFVQIIMEAWEKGLNPKGNAT---NPSNWDFSNSFFFAGTVITTIGYGNLYPSTVAGQVFCVFYALFGIPLNLAFLNLIGK 145
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: stk26 (serine/threonine kinase 26 [Source:Xenbase;Acc:XB-GENE-982067]) HSP 1 Score: 60.8474 bits (146), Expect = 6.738e-10 Identity = 44/137 (32.12%), Postives = 61/137 (44.53%), Query Frame = 3 Query: 90 VYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 +Y +G MF+++E Q E + + + R L NY LD + L F+ E K N N T N +W S F+ TVITTIGYG P T G+ + YA+ GIP L+ IG+ Sbjct: 22 LYLFLGAMMFQILEKQAESNTRDQFQVAKLRF---LQNYT--------CLDVNALEQFVQIIMEAWEKGLNPKGNAT---NPSNWDFSNSFFFAGTVITTIGYGNLYPSTVAGQVFCVFYALFGIPLNLAFLNLIGK 144
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk18 (potassium channel, subfamily K, member 18 [Source:MGI Symbol;Acc:MGI:2685627]) HSP 1 Score: 68.9366 bits (167), Expect = 2.654e-12 Identity = 41/142 (28.87%), Postives = 69/142 (48.59%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 + +V Y L+G +F +E + + + + ++K + + N LK N+++ + N E L LK + W+ ++ F TV +T+GYG P TR GKFL ++YA+ GIP FL L++IG Sbjct: 38 LCCLVTYALVGAALFSAVEGRPDPEAEENPE------LKKFLDDLCNILKCNLTVVEGSRKNL----CEHLQHLKPQWLKAP-----QDWSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGD 164
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk15 (potassium channel, subfamily K, member 15 [Source:MGI Symbol;Acc:MGI:2675209]) HSP 1 Score: 67.0106 bits (162), Expect = 6.271e-12 Identity = 45/145 (31.03%), Postives = 67/145 (46.21%), Query Frame = 3 Query: 66 AGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 A IL I+ Y L+G +F +E++ ER + QR++ + K S D EL +L + G W GS F++TVITTIGYG A P T GK + YA++GIP T ++ ++G+ Sbjct: 9 AALILCILSYLLVGAAVFDALESEAER--------SRQRLLARKRGEFRR--KYRFSADDYR----------ELERLALQAEPHRAGRQ---WRFAGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGE 130
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk15 (potassium channel, subfamily K, member 15 [Source:MGI Symbol;Acc:MGI:2675209]) HSP 1 Score: 67.0106 bits (162), Expect = 8.365e-12 Identity = 46/145 (31.72%), Postives = 68/145 (46.90%), Query Frame = 3 Query: 66 AGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 A IL I+ Y L+G +F +E++ ER + QR++ + K S D Y EL +L + G W GS F++TVITTIGYG A P T GK + YA++GIP T ++ ++G+ Sbjct: 28 AALILCILSYLLVGAAVFDALESEAER--------SRQRLLARKRGEFRR--KYRFSAD---------DY-RELERLALQAEPHRAGRQ---WRFAGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGE 149
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk16 (potassium channel, subfamily K, member 16 [Source:MGI Symbol;Acc:MGI:1921821]) HSP 1 Score: 65.0846 bits (157), Expect = 2.290e-11 Identity = 44/141 (31.21%), Postives = 67/141 (47.52%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIG 497 +L + Y L+G +F+L+E Q E + + + + R +E NY LD L F+ E K N N T N +W S F+ TV+TTIGYG P T G+ + YA++GIP + L+++G Sbjct: 18 LLAYICYLLLGATIFQLLEKQAEAQSRDQFQLEKLRFLE---NYT--------CLDQQALEQFVQVILEAWVKGVNPKGNST---NPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNHLG 144
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk9 (potassium channel, subfamily K, member 9 [Source:MGI Symbol;Acc:MGI:3521816]) HSP 1 Score: 64.3142 bits (155), Expect = 8.776e-11 Identity = 46/143 (32.17%), Postives = 65/143 (45.45%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTE-ELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 I Y L+G +F +E+ E R + K+K R+ K NIS D Y + EL L++E W GS F++TVITTIGYG A P T GK + YA++GIP T + ++G+ Sbjct: 12 IACTFTYLLVGAAVFDALESDHEMREEEKLKAEEVRLRGKY----------NISSD---------DYQQLELVILQSEPHRAGV-----QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE 130
BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|Q18120|TWK18_CAEEL (TWiK family of potassium channels protein 18 OS=Caenorhabditis elegans OX=6239 GN=twk-18 PE=1 SV=2) HSP 1 Score: 88.9669 bits (219), Expect = 5.352e-18 Identity = 63/201 (31.34%), Postives = 103/201 (51.24%), Query Frame = 3 Query: 12 LEIIKRGLSR-FTKFIFSCAG--SILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKN--EGWNGTFG------ENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFY--LFLRKSKFLKKQKEN 575 + I+ +G+S T F + G ++++V YTL+G ++F +IE + ER + ++ +K ++ + + Y +N L+ L+ EE ++ + T G + + WT GSI + +TV TTIGYG P T WG+F TI+YA IGIP T LSL +G F+K C FL+ ++ + K N Sbjct: 1 MAIVAQGVSTILTTFQKTFKGLLPLIILVAYTLLGAWIFWMIEGENEREMLIEQQKERDELIRR-TVYKINQLQ-------IKRQRRLMTAEEEYNRTAKVLTTFQETLGIVPADMDKDIHWTFLGSIFYCMTVYTTIGYGNIVPGTGWGRFATILYAFIGIPLTVLSLYCLGSLFAKG-CKMLWRFFLKSTRVVSKDLSN 192
BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|P34410|TWK7_CAEEL (TWiK family of potassium channels protein 7 OS=Caenorhabditis elegans OX=6239 GN=twk-7 PE=3 SV=3) HSP 1 Score: 75.0998 bits (183), Expect = 2.312e-13 Identity = 58/207 (28.02%), Postives = 99/207 (47.83%), Query Frame = 3 Query: 30 GLSRFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIK---LKMKKTSQ-RIVEKL---------SNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFC---GFYL---FLRKSKFLKKQKENFTRLIH 593 G+ +F K + +L+ YT++G +F +E E+ +K LK+ T Q V+ L Y SL E N+++ L E+ NE E +WT SI F++TV+TTIGYG P T G+ I+++++GIP T ++++++G+ S+ G YL +L S+ K+++E+ H Sbjct: 154 GIRKFAKLVLPHVALVLLTCTYTVIGALIFYSVEQPHEQMMKEQQLKLIYTRQNEFVDDLIRLAAGNETKRYEWESLAER---HMHNMSDQLFVAFEKYFLTSNEVKKNAATE---TWTFSSSIFFAVTVVTTIGYGNPVPVTNIGRIWCILFSLLGIPLTLVTIADLGKFLSEHLVWLYGNYLKLKYLILSRHRKERREHVCEHCH 354
BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|Q6Q1P3|KCNKI_RAT (Potassium channel subfamily K member 18 OS=Rattus norvegicus OX=10116 GN=Kcnk18 PE=2 SV=1) HSP 1 Score: 69.3218 bits (168), Expect = 1.290e-11 Identity = 43/141 (30.50%), Postives = 73/141 (51.77%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIG 497 + +V Y L+G +F +E + + + + ++K + + N LK N+++ + + E L +LK + W F E W+ ++ F TV +T+GYG P TR GKFL ++YA+ GIP FL L++IG Sbjct: 49 LCCLVTYALVGAALFSAVEGRPDPEAEENPE------LKKFLDKLCNILKCNLTVVEGSRKDL----CEHLQQLKPQ-W---FKAPE-DWSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIG 174
BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|Q6VV64|KCNKI_MOUSE (Potassium channel subfamily K member 18 OS=Mus musculus OX=10090 GN=Kcnk18 PE=1 SV=1) HSP 1 Score: 68.9366 bits (167), Expect = 1.857e-11 Identity = 41/142 (28.87%), Postives = 69/142 (48.59%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 + +V Y L+G +F +E + + + + ++K + + N LK N+++ + N E L LK + W+ ++ F TV +T+GYG P TR GKFL ++YA+ GIP FL L++IG Sbjct: 38 LCCLVTYALVGAALFSAVEGRPDPEAEENPE------LKKFLDDLCNILKCNLTVVEGSRKNL----CEHLQHLKPQWLKAP-----QDWSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGD 164
BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|Q8R5I0|KCNKF_RAT (Potassium channel subfamily K member 15 OS=Rattus norvegicus OX=10116 GN=Kcnk15 PE=2 SV=1) HSP 1 Score: 67.0106 bits (162), Expect = 4.397e-11 Identity = 45/145 (31.03%), Postives = 67/145 (46.21%), Query Frame = 3 Query: 66 AGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 A IL I+ Y L+G +F +E++ ER + QR++ + K S D EL +L + G W GS F++TVITTIGYG A P T GK + YA++GIP T ++ ++G+ Sbjct: 9 AALILCILSYLLVGAAVFDALESEAER--------SRQRLLARKRGEFRR--KYRFSADDYR----------ELERLALQAEPHRAGRQ---WRFAGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGE 130
BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: R7U1G0 (Uncharacterized protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_62385 PE=3 SV=1) HSP 1 Score: 182.57 bits (462), Expect = 4.100e-50 Identity = 134/391 (34.27%), Postives = 205/391 (52.43%), Query Frame = 3 Query: 39 RFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKE---NISLDPSNLNNFLLKYTEELS-KLKNEGWNGT--FGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFNEWL-IKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYKWK 1190 +F F+FS G ++V Y+++GGF+F+ IE E + K ++++ + IVE+L + LKE N + + + L Y +EL +K +GW+G E+ W+ G++L+++TVITTIGYG PKT G+ +TIVYA+IGIP TFL LSNIG + AF FY + F K+ E +++K +++ + R + H G ++ ID D + + E+ +K ++N +D E ++ V V +S +I YI G++ FT+WED DYL +YFCFITLSTIGFGDIVPGT + EKL+ V ++ GLS+ +MCF LM+EE++ K K Sbjct: 17 KFVTFLFSHIGLAALVVGYSILGGFLFRWIEAPSEWQEKYRIREVREDIVEQLQS-TATHLKEGQINATSFENKVRGVLFHYQKELILAVKEKGWDGNDDMSESSVQWSFAGALLYAVTVITTIGYGHVAPKTSAGRIVTIVYALIGIPLTFLYLSNIGNFLADAFRLFYKKVCCDVFCCKKCE---------------RKRKRERLKMRRRIVKNHTMGNSTALHDMAIDMDC-----------------AYDQLELGEYTDLKGNALNFVDDPFDYEDEDEDAKV-TVPVSIC---------LILIAGYIFAGSVLFTLWEDWDYLTGSYFCFITLSTIGFGDIVPGTDMKEWASHEKLVLCVLWLAFGLSLLAMCFNLMQEEVKEKIK 364
BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: A0A4D5S293 (Putative potassium channel subfamily protein k member (Fragment) OS=Ixodes scapularis OX=6945 PE=3 SV=1) HSP 1 Score: 157.918 bits (398), Expect = 1.296e-40 Identity = 120/388 (30.93%), Postives = 196/388 (50.52%), Query Frame = 3 Query: 39 RFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQE----RRIKLKMKKTSQRIVEKLSNYILNSL-KENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDN-PKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYK 1184 RFT F+FS G ++V Y+++G F F+ +E E ++ L ++T +R+ E + N L +EN + + +++ +L + L +G++G W+ G+ L+SLTVITTIGYG P+T WGK +TI+YAI+GIP L L+NIG +KAF Y L + + + +R P L++ ++ Y+ H +V N++D + +++ V V L D ++ V ++ F I+I YI GA+ F++WE ++L +YFCF+TLSTIGFGD+VPG + SD+ +EKL+ Y++VG+++ +MCF LM+EE+ YK Sbjct: 26 RFTAFLFSHVGLCALVVGYSILGAFAFRALEAPYEVEKASQVILMREQTVRRLWEITDRF--NVLYRENWT---AAVSSEILDFQGRLIAAVKDGYDGKEIGTGQQWSFSGAFLYSLTVITTIGYGNIAPRTNWGKMVTILYAIVGIPLMLLYLTNIGDILAKAFRYVYGKLCTCRPAQHPQR--------RRRQPLPLHNHLQRNAAVENYRVHH------IVGHNSVD--------------------------LQDGKLRDDPVRVESLADDDVYEGGAKPRVSVPITLC---------FVIMIGYISGGAVIFSLWEGWEFLDGSYFCFVTLSTIGFGDLVPGDTVVSDSGSQEKLVICSLYLLVGMALIAMCFNLMQEEVIYK 359
BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: A0A194PRB2 (Potassium channel subfamily K member 18 OS=Papilio xuthus OX=66420 GN=RR46_11704 PE=3 SV=1) HSP 1 Score: 144.436 bits (363), Expect = 1.926e-35 Identity = 112/400 (28.00%), Postives = 194/400 (48.50%), Query Frame = 3 Query: 48 KFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKY--TEELSKLKNE-------GWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKH----PKGERNLVNWNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFN----------EWLIKNQSVNVSYLTYDRE-IPEQSETVEQVNLSYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEI 1175 F+FS G I+++V YT+ G FMF+ IE E +++ + +E+ N L +N++L + N LKY ELSK +++ GW+G G + W+ + L+SLTVIT+IGYG +P+T WGK +TI YA++G+P L ++N+GQ ++ F Y L+ + R P +++ ++ ++L P+G R+ V+ +++ D I D D + +++++ + SY+T+D + I V + Y I+ G++ F +WE D L AYFCFI+LS+IGFGD VPG ++ + + I Y+++G+++ +MCF LM+E++ Sbjct: 21 AFLFSNIGLIVLVVGYTVAGAFMFQAIEGASE------IERVNNMTLER--NNTAQYLWQNVTLALNLFNETALKYRLNIELSKYQSKIVTAVRNGWDG--GRSSRQWSFSSAFLYSLTVITSIGYGHLSPRTSWGKVMTIFYALLGMPLFLLYVTNVGQLLARWFKCLY-----------------ALVCLCRGCPGFGRRRVVRLRTQLETSEAESIECPEGWRHRVSESDVTPDYRIPPYAIYHQRRLDIRRLPHPLDPRYPHDRGWSEPAYRVESEASDFSYVTFDAQTITVPISVCVAVMVGY-----------------IMFGSMIFGLWEKWDQLDGAYFCFISLSSIGFGDFVPGERVYTPRIETSFIVCSLYLMLGIALGAMCFNLMQEQV 376
BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: A0A085M6W1 (Uncharacterized protein OS=Trichuris suis OX=68888 GN=M513_06073 PE=3 SV=1) HSP 1 Score: 138.658 bits (348), Expect = 1.097e-32 Identity = 119/401 (29.68%), Postives = 214/401 (53.37%), Query Frame = 3 Query: 39 RFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSN---LNNFLLK-YTEELSKLKN-EGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKF---LKKQKENFTRL---IHIKRSLPKQQEKKLKKVSSKLRYKRKHP---KGERN------LVNWNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNL--SYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEI 1175 + +FS G ++ Y MG +F+ IE E+ ++ M+ +Q I+++L L KE L+P L + LLK Y +L N EG++G + +Y WT G++L+S+T+ TTIGYG PKT+ G+ +TI+YA+IGIP L L+NI + F +++ R F +KKQ+ R + ++P+ K +++ LR +P +G+++ +++N+DS+ ++S + + D E + ++ + + + D + E+S L Y ++P+++ ++ +IL GA+ F +WE+ + AYF F+TL+TIGFGD+VPG +DS + +EKLI Y++ G+++ +MCFKLM++++ Sbjct: 18 KVISLLFSHIGLCSLVASYAAMGAAVFRAIEFPLEQEVQGHMRNDTQLIMKEL----LKFTKEQAVLNPREWMELADGLLKDYETKLVHAVNFEGYDGEDEQIKYQWTFFGALLYSITIFTTIGYGHICPKTKLGRAITILYAMIGIPLMLLCLANIADSLVRLFT--FVYSRICCFYCRMKKQERWMKRANISVRYTNTVPRFNPCK-GNLNTSLRQSSTYPSFVEGKKSSSLRSKPTDFSNVDSNTVQLPKIVITNNSGETDVHWNLSDDEEVVGTSERSHEADVRSDFKRYEESAVKVPKRLVNQYRYEKVPVSVGILTVVLFILGGAVLFAVWENWNVFDGAYFSFVTLTTIGFGDMVPGKSLDSGS-QEKLIICSLYLLFGMALIAMCFKLMQDDV 410
BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: A0A0K0EYV5 (Potassium channel subfamily K member 18 (inferred by orthology to a human protein) OS=Strongyloides venezuelensis OX=75913 PE=3 SV=1) HSP 1 Score: 135.576 bits (340), Expect = 2.513e-32 Identity = 113/384 (29.43%), Postives = 191/384 (49.74%), Query Frame = 3 Query: 33 LSRFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPK-QQEKKLKKVSSKLRYKRKHPKGERNLV-NWNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSD-NPKEKLIXXXXXXXXXXXXXSMCFKLMEEEI 1175 + R F FS G +++ Y L+G +F+ +E E+ ++ +++ QR V+ N K N S + + + K+ + +G++G WT G+ L+SLTVITTIGYG + KT +GK LTI++AIIGIP L L+NIG +K F +L+ R +F K N L H KR K ++ L ++ + R++ R +V + ++DS F + N S +V + R +Q E E V +I +P+ + ++ Y++ GA+ F +WE +L YF +I+L+TIGFGD+ PG + +D + ++KL+ Y++ G+++ +MCF L +EE+ Sbjct: 17 VKRIIAFFFSHVGLCALVIGYALLGAVVFRAVEGPHEQFVQSEIQIARQRAVDITWNATFRVNKLNKSQWQRVVFSQVKKFQKRTMWAIRKGYDGKEYGVSAQWTFTGAFLYSLTVITTIGYGNTSAKTYFGKTLTILFAIIGIPLMLLFLTNIGDVMAKIFR--FLYARSIRF----KYNVI-LWHKKRQAAKIRKANSLVAKLARAQTMRQYNGNLRGMVRDDTSLDSMGFG--------------------------VTNAS-DVREMLVARAHLDQLEVKESVEAQLQRISVPLFLVLLTMLAYLIAGAILFCLWEGWTFLDAFYFAYISLTTIGFGDLFPGASVGNDKDAQKKLVITSVYLLFGMALLAMCFNLAQEEV 366
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: KCNK4 (potassium channel subfamily K member 4-like [Source:NCBI gene;Acc:103026898]) HSP 1 Score: 75.485 bits (184), Expect = 2.217e-14 Identity = 46/145 (31.72%), Postives = 68/145 (46.90%), Query Frame = 3 Query: 84 IVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 +++Y +MG +F +E E +K + + L N L+ + NL+ L TE + N N TF SW L + FS T+ITTIGYG +P+T+WGK I YA++GIP L+ +G H Sbjct: 76 VLLYLVMGALVFNALEAPAE-------EKQYNELYDNLRNTCSIFLESYSCISSENLHELLENITEAIEAGVNAK-NNTFSS---SWDLASAFFFSGTIITTIGYGNISPQTKWGKLFCICYALVGIPLFGFLLAGVGDHLGTGL 209
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: KCNK4 (potassium channel subfamily K member 4-like [Source:NCBI gene;Acc:103026898]) HSP 1 Score: 75.0998 bits (183), Expect = 2.661e-14 Identity = 46/145 (31.72%), Postives = 68/145 (46.90%), Query Frame = 3 Query: 84 IVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 +++Y +MG +F +E E +K + + L N L+ + NL+ L TE + N N TF SW L + FS T+ITTIGYG +P+T+WGK I YA++GIP L+ +G H Sbjct: 30 VLLYLVMGALVFNALEAPAE-------EKQYNELYDNLRNTCSIFLESYSCISSENLHELLENITEAIEAGVNAK-NNTFSS---SWDLASAFFFSGTIITTIGYGNISPQTKWGKLFCICYALVGIPLFGFLLAGVGDHLGTGL 163
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: KCNK4 (potassium channel subfamily K member 4-like [Source:NCBI gene;Acc:103026898]) HSP 1 Score: 75.0998 bits (183), Expect = 2.668e-14 Identity = 46/145 (31.72%), Postives = 68/145 (46.90%), Query Frame = 3 Query: 84 IVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 +++Y +MG +F +E E +K + + L N L+ + NL+ L TE + N N TF SW L + FS T+ITTIGYG +P+T+WGK I YA++GIP L+ +G H Sbjct: 13 VLLYLVMGALVFNALEAPAE-------EKQYNELYDNLRNTCSIFLESYSCISSENLHELLENITEAIEAGVNAK-NNTFSS---SWDLASAFFFSGTIITTIGYGNISPQTKWGKLFCICYALVGIPLFGFLLAGVGDHLGTGL 146
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: kcnk6 (potassium two pore domain channel subfamily K member 6 [Source:NCBI gene;Acc:103034804]) HSP 1 Score: 70.4774 bits (171), Expect = 4.220e-13 Identity = 51/164 (31.10%), Postives = 79/164 (48.17%), Query Frame = 3 Query: 33 LSRFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEE----LSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSK 512 +S F + G +L VVY L+G +F IE E + ++ +I++ LS ++ S L +FL K +S L+N + G N W L S+ F+ T++TT+GYG TP + GK +IVYA+ G+PFT L L+ Q + Sbjct: 1 MSPFLRSFLLLGGLVLAYVVYLLLGALVFSAIERPVEDSLHSELSSLKAQILQ-LS-----------CINASTLEDFLEKVLRANKYGVSVLRNV----SVGSN---WDLASSLFFANTLVTTVGYGHTTPLSDAGKTFSIVYALFGVPFTMLVLTACVQRLMR 145
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: ENSAMXT00000047723.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:15897283:15919205:1 gene:ENSAMXG00000033807.1 transcript:ENSAMXT00000047723.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 70.4774 bits (171), Expect = 8.889e-13 Identity = 46/161 (28.57%), Postives = 78/161 (48.45%), Query Frame = 3 Query: 66 AGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKS 548 A IL ++VY L+G +F IE Q L++ + ++ V ++ N N +N++ +L+ E K+ E + + ++ W GS+ F TV TT+GYG P T+ G+ I+YA +GIP L ++++G + F Y L S Sbjct: 140 AALILSLIVYALLGAALFHAIEGTQSNDGTLEIHEGFRKFVHEVVNEARNKSTS------ANVSEEVLEAVGE--KILRE-FKAVWMQSSDRWHFYGSLFFCCTVFTTVGYGEIYPVTKAGRVACILYATVGIPLMLLVITDVGDILAVLFSNSYRRLHSS 291
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003416.1 (pep scaffold:Pmarinus_7.0:GL476517:78247:80718:1 gene:ENSPMAG00000003129.1 transcript:ENSPMAT00000003416.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.9442 bits (180), Expect = 1.659e-15 Identity = 62/242 (25.62%), Postives = 104/242 (42.98%), Query Frame = 3 Query: 342 WTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVN--WNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVP 1061 W GS+ F T+ TTIGYG P T GK + +VYA GIP L L+++G ++ Y R + L + H P+ + L++ +K+ +H +GE + V+ + SD+ + VS + ++PE V+++++ ++ + F I+ Y++ G WE+ YL YF F+T++TIG GDIVP Sbjct: 2 WNFLGSLFFCCTIFTTIGYGHIAPSTDGGKIMCMVYATFGIPIMLLVLADVGDLLARTLTTIYTSFRH-RLLPGARCGRQ---HPPGDGPEGND--LQRSRTKIDDSHRH-EGEDDAVDVPLKSPGSDVEGG--------------------------RELPATVS-IAEGADVPEADREVKELDVPFT-------LIFLIVFVYLMFGTFLLPCWEEWSYLDAFYFVFVTMTTIGLGDIVP 202
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: kcnk7 (potassium channel, subfamily K, member 7 [Source:ZFIN;Acc:ZDB-GENE-110304-2]) HSP 1 Score: 71.2478 bits (173), Expect = 3.672e-14 Identity = 40/138 (28.99%), Postives = 68/138 (49.28%), Query Frame = 3 Query: 87 VVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 +Y ++G +F +E E R+++ +++ V +++ L L FL E + + N T G + W ++ F+ TV+TT+GYG P + GK L I+YA++GIPFT L L++I Q Sbjct: 17 ALYLVLGAIVFSTLERPYEERLRMDVRRLRDAFV-----------RQHACLSDEALEGFLRDALEARTHGVSALRNATAGPH---WDFVSALFFASTVLTTVGYGHTVPLSDAGKALCILYAVLGIPFTLLLLTSIVQ 140
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: KCNK16 (potassium two pore domain channel subfamily K member 16 [Source:HGNC Symbol;Acc:HGNC:14464]) HSP 1 Score: 65.4698 bits (158), Expect = 2.805e-12 Identity = 40/136 (29.41%), Postives = 69/136 (50.74%), Query Frame = 3 Query: 87 VVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGE--NEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLS 488 V Y L G +F+++E E+ I+ QR+ + + +I N + +D L+ FL +E+ ++ G G+ + +W ++LF++TV+TTIGYG P + WG+ YA++GIP LS Sbjct: 13 VAYLLAGAAVFQVLELPAEQNIR-------QRLTDSWAAFIQN----HSCVDDGTLDLFL----QEVLDARSHGVRVAAGQASSPSNWDFSSALLFTVTVVTTIGYGSTAPGSTWGRASCAFYALLGIPLNLQLLS 133
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: KCNK16 (potassium two pore domain channel subfamily K member 16 [Source:HGNC Symbol;Acc:HGNC:14464]) HSP 1 Score: 64.6994 bits (156), Expect = 3.887e-12 Identity = 40/136 (29.41%), Postives = 69/136 (50.74%), Query Frame = 3 Query: 87 VVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGE--NEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLS 488 V Y L G +F+++E E+ I+ QR+ + + +I N + +D L+ FL +E+ ++ G G+ + +W ++LF++TV+TTIGYG P + WG+ YA++GIP LS Sbjct: 23 VAYLLAGAAVFQVLELPAEQNIR-------QRLTDSWAAFIQN----HSCVDDGTLDLFL----QEVLDARSHGVRVAAGQASSPSNWDFSSALLFTVTVVTTIGYGSTAPGSTWGRASCAFYALLGIPLNLQLLS 143
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: KCNK10 (potassium two pore domain channel subfamily K member 10 [Source:HGNC Symbol;Acc:HGNC:6273]) HSP 1 Score: 53.9138 bits (128), Expect = 2.333e-8 Identity = 23/59 (38.98%), Postives = 32/59 (54.24%), Query Frame = 3 Query: 342 WTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 W L + F+ TV+TTIGYG +P T WG+ YA++GIP L+ +G F Sbjct: 102 WDLGSAFFFAGTVLTTIGYGNVSPSTDWGRIFCTAYALVGIPIFGFLLAGVGDQLGTIF 160
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO35923 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK42]) HSP 1 Score: 87.0409 bits (214), Expect = 7.667e-20 Identity = 59/173 (34.10%), Postives = 87/173 (50.29%), Query Frame = 3 Query: 90 VYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSL 608 VY L G +F+ IE+ +ERR + + Q ++EK NIS ++ N +E+SK +EG+ F N W+ GS+ F+ TV+TTIGYG P T WG+ I YAI GIP T L L +IG+ ++ F+ + + F + K IH+K L Sbjct: 2 VYLLFGAAVFQTIESGEERRERHHFEFVRQNLIEKY----------NIS--EKDMRNLF----KEISKAIDEGY---FDVNYDRWSFAGSLFFTGTVVTTIGYGQMAPATVWGRVFCIFYAIFGIPITGLMLKSIGERITEGIADFWRIIDRRLFNRDPKS-----IHMKTVL 150
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO47668 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLC5]) HSP 1 Score: 70.8626 bits (172), Expect = 9.002e-14 Identity = 47/151 (31.13%), Postives = 80/151 (52.98%), Query Frame = 3 Query: 87 VVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIG----QHFSKAFCGF 527 ++Y +MG +F+ +E+ E++ + +++K QRI K N +KE + + + K + G + E W+ GS+ FS TVITTIGYG +P+T +G+ ++YA+ GIP T+L L+++G +H S GF Sbjct: 20 ILYLVMGMVVFRFLESGHEKKEREQVQKDIQRIRHKF-NISRKEMKE---------------FVDVVQKAASFGLTQDWLEK---WSYTGSLFFSGTVITTIGYGHLSPETFFGRIFCMLYALFGIPITWLMLTSLGKKIVEHISSFLQGF 151
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO37267 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG83]) HSP 1 Score: 66.6254 bits (161), Expect = 9.274e-13 Identity = 53/205 (25.85%), Postives = 85/205 (41.46%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGEN------EYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKH 671 + ++ Y L+G F+F+L+E + L+E + + N L KY +S+ W TF N W S +F++ +TTIGYG PKT G+ I YA++GIP T L+L IG S+ C FL + + LK+ + L S+ L ++S + Y++ Sbjct: 15 VFLLTGYLLIGAFIFQLLERKN----------------------FATELRETVEIR----RNILAKY--NISRHDASRWARTFLSNPLMENISLEWNFGNSFVFAMVTVTTIGYGNIVPKTFGGRLFCIFYALLGIPGTCLTLKAIGDKISEKLCALIKFL-EMRVLKRPRPQHLELKTAVTSIVMAVCVVLPLLASVVYYRKSE 190
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO47667 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLC4]) HSP 1 Score: 63.929 bits (154), Expect = 5.412e-12 Identity = 45/157 (28.66%), Postives = 77/157 (49.04%), Query Frame = 3 Query: 93 YTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYS--WTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGF--YLFLRKSK 551 Y +G +F+ +E + E + M + ++ ++ ++ FL E + ++ + G++ E+S W+L GS+ F+ TV+TTIGYG TP T G+ I YA++GIP T+L LS + Q + C YL+ R S+ Sbjct: 7 YIFLGAVIFQALEAKNEMAERRAMSFARLK------------FQQRYNISDEDMKVFL----ERIEEIVDHGFS-----REWSRRWSLLGSLFFAGTVVTTIGYGHVTPCTISGRVFCIFYALVGIPLTWLLLSTLAQGVNNMICASIRYLYDRFSR 142
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO33193 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSX6]) HSP 1 Score: 63.929 bits (154), Expect = 1.185e-11 Identity = 27/60 (45.00%), Postives = 36/60 (60.00%), Query Frame = 3 Query: 327 ENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHF 506 N Y W+ GS+ F+ TVITTIGYG P+T GK ++YA +GIP +IG+ F Sbjct: 74 ANLYQWSFAGSVYFATTVITTIGYGHTVPRTPRGKIFCMIYAAVGIPLALTMFQSIGERF 133
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: KCNK4 (potassium channel subfamily K member 4 [Source:NCBI gene;Acc:101166075]) HSP 1 Score: 75.0998 bits (183), Expect = 2.589e-14 Identity = 45/143 (31.47%), Postives = 77/143 (53.85%), Query Frame = 3 Query: 84 IVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEK-LSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYS-WTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHF 506 +++Y ++G +F+ +E ER+I+ + +K R+ E L N+ ++P +L +FL K E + EG + E ++ W L + FS T+ITTIG+G +P+T GK I YA++GIP + L+ +G H Sbjct: 13 VLLYLVLGAVVFRTLEIPNERKIQEESEKQLSRVREHFLGNFSC--------VEPESLLDFLQKVEEVI-----EGLGSSSNETSFTKWDLASAFFFSGTIITTIGFGNISPQTDGGKLFCIFYALVGIPMFGILLAGVGDHL 142
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: KCNK4 (potassium channel subfamily K member 4 [Source:NCBI gene;Acc:101166075]) HSP 1 Score: 73.1738 bits (178), Expect = 8.101e-14 Identity = 44/142 (30.99%), Postives = 74/142 (52.11%), Query Frame = 3 Query: 84 IVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEK-LSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHF 506 +++Y ++G +F+ +E ER+I+ + +K R+ E L N+ ++P +L +FL + E L NE + W L + FS T+ITTIG+G +P+T GK I YA++GIP + L+ +G H Sbjct: 13 VLLYLVLGAVVFRTLEIPNERKIQEESEKQLSRVREHFLGNFS--------CVEPESLLDFLQEVIEGLGSSSNE-------TSFTKWDLASAFFFSGTIITTIGFGNISPQTDGGKLFCIFYALVGIPMFGILLAGVGDHL 139
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: kcnk6 (potassium two pore domain channel subfamily K member 6 [Source:NCBI gene;Acc:101164174]) HSP 1 Score: 65.4698 bits (158), Expect = 1.496e-11 Identity = 45/147 (30.61%), Postives = 73/147 (49.66%), Query Frame = 3 Query: 66 AGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFG--ENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 +G +L V+Y L G +F IE E R++ M+ ++ E L+ +N+ ++L FLLK N+ G +W L S+ F+ T++TT+GYG +P + GK +I YA++G+PFT L L+ Q Sbjct: 12 SGFVLFYVIYLLFGALVFSSIERPVEERLRHDMQVLTE---EFLNRSCVNA---------ASLELFLLKVLR-----ANKYGVSVIGNFSGATNWDLPSSMFFANTLVTTVGYGHTSPLSDAGKAFSIFYALLGVPFTMLVLTACVQ 141
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: kcnk10b (potassium two pore domain channel subfamily K member 10 [Source:NCBI gene;Acc:101162012]) HSP 1 Score: 65.855 bits (159), Expect = 2.912e-11 Identity = 48/170 (28.24%), Postives = 77/170 (45.29%), Query Frame = 3 Query: 78 LMIVVYTLMGGFMFKLIEN--QQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELS---KLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKE 572 +++V+Y + G FK +E + ++ L ++K S L+ + + P LN + + +S + + +N +F W L + F+ TVITTIGYG P T+ GK I YAI GIP L+ IG F L + K +F +K K+ Sbjct: 105 IVVVLYLICGALAFKALEQPFETNQKTSLTLQKAS-------------FLERHPCVSPDELNTIIEHAMDAVSPGLRPLDTTYNSSF------WDLSSAFFFAGTVITTIGYGNIAPSTQGGKIFCIFYAIFGIPLFGFLLAGIGDQLGTIFVKSILKVEK-RFRQKHKQ 254
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: kcnk3b (potassium channel subfamily K member 3 [Source:NCBI gene;Acc:101165434]) HSP 1 Score: 65.0846 bits (157), Expect = 3.796e-11 Identity = 43/142 (30.28%), Postives = 71/142 (50.00%), Query Frame = 3 Query: 75 ILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQ 500 I+ I+ Y ++G +F+ +E++QER + K++ R E L Y N + N +L +L+ + ++ W GS F++TVITTIGYG A P T GK + YA++GIP T + ++G+ Sbjct: 12 IVSILTYLVVGAAVFETLESKQERSQRRKLEA---RKYELLRRY--NLTRANFE----DLELVVLQLKPHKAGVQ--------------WKFAGSFYFAITVITTIGYGHAAPSTDSGKVFCMFYALLGIPLTLVMFQSLGE 130
BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000019992.1 (SMESG000019992.1) HSP 1 Score: 607.06 bits (1564), Expect = 0.000e+0 Identity = 370/371 (99.73%), Postives = 371/371 (100.00%), Query Frame = 3 Query: 81 MIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYKWKT 1193 MIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFIYSIESDESSSSDDAIPEIEEDFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQIRIPIAITFAI+ICYILIGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIFVVFYVVVGLSVFSMCFKLMEEEIRYKWKT Sbjct: 1 MIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFIYSIESDESSSSDDAIPEIEEDFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQIRIPIAITFAIMICYILIGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIFVVFYVVVGLSVFSMCFKLMEEEIRYKWKT 371
BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000019992.1 (SMESG000019992.1) HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0 Identity = 363/364 (99.73%), Postives = 364/364 (100.00%), Query Frame = 3 Query: 102 MGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYKWKT 1193 MGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFIYSIESDESSSSDDAIPEIEEDFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQIRIPIAITFAI+ICYILIGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIFVVFYVVVGLSVFSMCFKLMEEEIRYKWKT Sbjct: 1 MGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFIYSIESDESSSSDDAIPEIEEDFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQIRIPIAITFAIMICYILIGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIFVVFYVVVGLSVFSMCFKLMEEEIRYKWKT 364
BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000019992.1 (SMESG000019992.1) HSP 1 Score: 553.132 bits (1424), Expect = 0.000e+0 Identity = 343/344 (99.71%), Postives = 344/344 (100.00%), Query Frame = 3 Query: 162 MKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFXXXXXXXXXXXXXXXXXXXXXXFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQXXXXXXXXXXXXXXXXXXGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYKWKT 1193 MKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFIYSIESDESSSSDDAIPEIEEDFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQIRIPIAITFAI+ICYILIGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIFVVFYVVVGLSVFSMCFKLMEEEIRYKWKT Sbjct: 1 MKKTSQRIVEKLSNYILNSLKENISLDPSNLNNFLLKYTEELSKLKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAFCGFYLFLRKSKFLKKQKENFTRLIHIKRSLPKQQEKKLKKVSSKLRYKRKHPKGERNLVNWNNIDSDLFIYSIESDESSSSDDAIPEIEEDFNEWLIKNQSVNVSYLTYDREIPEQSETVEQVNLSYSQIRIPIAITFAIMICYILIGALFFTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIFVVFYVVVGLSVFSMCFKLMEEEIRYKWKT 344
BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000068804.1 (SMESG000068804.1) HSP 1 Score: 116.316 bits (290), Expect = 6.360e-28 Identity = 91/275 (33.09%), Postives = 136/275 (49.45%), Query Frame = 3 Query: 12 LEIIKRGLSRFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKENISLD-----------------PSN---LNNFL----LKYTEELSK-LKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF-------CGFYLFLRKSKFLKKQKENFTRLIH-----------IKRSLPKQQ-------EKKLKKVSSKL-RYKRKHPKGE 683 +E K+ RF F+FS G ++V Y ++GGFMF+ +E E T +R+ + +++I ++K ISL+ P N LNN+L + YT + ++ EGWNG +W+ EG++L+ LTVITTIGYG PKT+ GKF+T++YA++GIP TFL LSNIG + + F C Y + K K ++LI IKR PKQ +K +K++ KL R+ K K + Sbjct: 60 IEKTKQCCKRFFTFLFSHIGLSAILVGYVIIGGFMFQSLEISNEIN-------TKKRVKDHRNDFIKATIKNLISLNLTWNNTDIMNNSSDINKPGNQTLLNNYLTMVIINYTNNVIFFMQEEGWNGNDDVTALNWSYEGALLYVLTVITTIGYGHVAPKTKLGKFITMLYALLGIPLTFLYLSNIGDYLADWFRFIYHKVCRKYCKMCCQKSRKHHSGLRSKLIKANAFPGMSKKVIKRDRPKQMIKPNNFFDKSIKQLREKLMRFPLKTKKSD 327 HSP 2 Score: 103.99 bits (258), Expect = 7.258e-24 Identity = 55/73 (75.34%), Postives = 65/73 (89.04%), Query Frame = 3 Query: 972 FTIWEDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYKWK 1190 FT+W D D+LKW+YFCFITLSTIGFGDIVPGTK+DS NPKEKLI V YV++GLSVF+MCFKLM+EE+ K+K Sbjct: 548 FTVWGDLDFLKWSYFCFITLSTIGFGDIVPGTKVDSKNPKEKLIIVSIYVIIGLSVFAMCFKLMQEEVVAKFK 620
BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000019203.1 (SMESG000019203.1) HSP 1 Score: 109.383 bits (272), Expect = 3.424e-26 Identity = 65/162 (40.12%), Postives = 93/162 (57.41%), Query Frame = 3 Query: 42 FTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIKLKMKKTSQRIVEKLSNYILNSLKE--NISLDPSNLNNFLLKYTEELSK-LKNEGWNGTFGENEYSWTLEGSILFSLTVITTIGYGVATPKTRWGKFLTIVYAIIGIPFTFLSLSNIGQHFSKAF 518 F +FS G ++V YT++GGF+F IE E +K +MK KL + + +K N S +N+ L ++ + + GWNG + E +W+ EGSIL+S+TVITTIGYG TPKT+ G+ TI YAI GIP T L L+NIG + ++ F Sbjct: 20 FCSCLFSHIGLSGLVVAYTILGGFLFYNIEISGEINVKNQMKIVRNETENKLEQILSSEMKADFNSSEILTNIRAILNEHERIFKENIFENGWNGRYEITENNWSYEGSILYSVTVITTIGYGHVTPKTKLGRIFTIFYAIFGIPLTILYLNNIGDYLAEIF 181 HSP 2 Score: 99.7525 bits (247), Expect = 9.762e-23 Identity = 55/79 (69.62%), Postives = 61/79 (77.22%), Query Frame = 3 Query: 960 GALFFTIW-EDNDYLKWAYFCFITLSTIGFGDIVPGTKIDSDNPKEKLIXXXXXXXXXXXXXSMCFKLMEEEIRYKWKT 1193 GA FT W DNDYLKW+YFCFITLSTIGFGDIVPG + NPKEKLI V YV +GL VF+MCFKLME+EI K K+ Sbjct: 341 GAFLFTFWGSDNDYLKWSYFCFITLSTIGFGDIVPGISVSDLNPKEKLIVSVLYVAIGLPVFAMCFKLMEDEIVNKVKS 419 The following BLAST results are available for this feature:
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034472 ID=SMED30034472|Name=Potassium channel subfamily K member 18|organism=Schmidtea mediterranea sexual|type=transcript|length=1195bpback to top protein sequence of SMED30034472-orf-1 >SMED30034472-orf-1 ID=SMED30034472-orf-1|Name=SMED30034472-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=397bp FRSLEIIKRGLSRFTKFIFSCAGSILMIVVYTLMGGFMFKLIENQQERRIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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