Protein tyrosine phosphatase type IVA

Overview


Name	Protein tyrosine phosphatase type IVA
Smed ID	SMED30034467
Length (bp)	1525

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein tyrosine phosphatase type IVA (SMED30034467) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein tyrosine phosphatase type IVA (SMED30034467) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein tyrosine phosphatase type IVA (SMED30034467) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein tyrosine phosphatase type IVA (SMED30034467) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034467

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30034467	SMESG000015894.1 SMESG000000559.1	Contig1506	GPL15192	PMID:23079596 Forsthoefel et al., 2012
epidermis	SMED30034467	SMESG000015894.1 SMESG000000559.1	Contig1506	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30034467	SMESG000015894.1 SMESG000000559.1	Contig1506	GPL15192	PMID:23079596 Forsthoefel et al., 2012
gut	SMED30034467	SMESG000078978.1	Contig1506	GPL15192	PMID:23079596 Forsthoefel et al., 2012
epidermis	SMED30034467	SMESG000078978.1	Contig1506	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30034467	SMESG000078978.1	Contig1506	GPL15192	PMID:23079596 Forsthoefel et al., 2012
X1 cell	SMED30034467	SMESG000078867.1 SMESG000010171.1	SmedASXL_011938	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
protonephridia	SMED30034467	SMESG000078978.1 SMESG000078867.1 SMESG000010171.1	dd_Smed_v4_2239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30034467	SMESG000078978.1 SMESG000078867.1 SMESG000010171.1	dd_Smed_v4_2239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior side	SMED30034467	SMESG000078978.1 SMESG000078867.1 SMESG000010171.1	dd_Smed_v4_2239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior muscle cell	SMED30034467	SMESG000078978.1 SMESG000078867.1 SMESG000010171.1	dd_Smed_v4_2239_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Human
Match: PTP4A3 (protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636])

HSP 1 Score: 159.073 bits (401), Expect = 1.184e-45
Identity = 72/158 (45.57%), Postives = 98/158 (62.03%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++YKHM FLI  +P+   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  L+K +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++YKHM FLI  +P+   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  L+K +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++YKHM FLI  +P+   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  L+K +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++YKHM FLI  +P+   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  L+K +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Human
Match: PTP4A2 (protein tyrosine phosphatase 4A2 [Source:HGNC Symbol;Acc:HGNC:9635])

HSP 1 Score: 157.918 bits (398), Expect = 2.800e-45
Identity = 71/157 (45.22%), Postives = 103/157 (65.61%), Query Frame = 1

Query:  235 FQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
              +P    I+Y++M FLI  +P+   ++ F EE K+  VT +VRVC++ Y +   +  GI++  W F DG+PPP+ I++ W  LLK +F  +      +AVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    1 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKF--REEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRL 155

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BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Celegans
Match: T19D2.2 (Putative prenylated protein tyrosine phosphatase [Source:UniProtKB/TrEMBL;Acc:G5EG43])

HSP 1 Score: 166.392 bits (420), Expect = 1.118e-48
Identity = 74/161 (45.96%), Postives = 107/161 (66.46%), Query Frame = 1

Query:  223 SARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            +A  + KP  + I +  M FLI D P+  ++  + EE ++     VVRVCE  Y   A K+ GI++  W+FSDGSPPP ++++ WFQL    F  + H + SIAVHC+AG GRAPVLVA+AL+E GM  EDA+EMIR++R+G+ N++Q+ +L  Y+A   L
Sbjct:   15 AATTYFKPAPSEIAWGKMRFLITDRPNNSSIQSYIEELEKHGARAVVRVCEPTYDTLALKEAGIDVLDWQFSDGSPPPPEVIKSWFQLCMTSF--KEHPDKSIAVHCVAGLGRAPVLVAIALIEAGMKYEDAVEMIRTQRRGALNQKQLKFLETYKANGEL 173

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BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Celegans
Match: frg-1 (pep chromosome:WBcel235:III:12979162:12980163:1 gene:WBGene00014177.1 transcript:ZK1010.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:frg-1)

HSP 1 Score: 88.9669 bits (219), Expect = 1.267e-19
Identity = 64/184 (34.78%), Postives = 100/184 (54.35%), Query Frame = -2

Query:  988 HKSGEPPSEDEILSCM-VLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQ----SFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYC 1524
            H  GE P+ +EI + +    D+KISLKTG+ +YVG++ +     + A+ +A+G  EQ+  +F+EGK A    +S        N +  +   S     +E + IR +  + E P++   VE+R  A + E  YVK +Q      +   + +  +DK  +KKA+  G  HE LLDRR KMK+DRYC
Sbjct:   95 HPEGEGPNPEEIFALVKTPDDSKISLKTGFGRYVGVDSE---YQLVAMAEAIGSREQFVLVFQEGKTAFQAVSSPLFLSTVPNKEGHIYVASRTATENEMVNIRTD-AIQEGPVDWRSVEDRKNARECETAYVKMYQHSKVDLKNRHIAIDVKDKKGVKKAQADGSAHELLLDRRMKMKSDRYC 274

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BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Celegans
Match: cdc-14 (Tyrosine-protein phosphatase cdc-14 [Source:UniProtKB/Swiss-Prot;Acc:P81299])

HSP 1 Score: 54.299 bits (129), Expect = 1.622e-7
Identity = 34/111 (30.63%), Postives = 54/111 (48.65%), Query Frame = 1

Query:  349 VTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALM-ELGMHCEDAIEMIRSKRKGSFNERQISYL 678
            V+ +VR+   +Y    F   G +     F DGS P  +I+ K+ +++ +       + G +AVHC AG GR   L+A  +M E G+   + +  +R  R GS    Q  YL
Sbjct:  238 VSTIVRLNAKNYDASKFTKAGFDHVDLFFIDGSTPSDEIMLKFIKVVDN-------TKGGVAVHCKAGLGRTGTLIACWMMKEYGLTAGECMGWLRVCRPGSVIGPQQPYL 341

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Celegans
Match: cdc-14 (Tyrosine-protein phosphatase cdc-14 [Source:UniProtKB/Swiss-Prot;Acc:P81299])

HSP 1 Score: 54.299 bits (129), Expect = 1.637e-7
Identity = 34/111 (30.63%), Postives = 54/111 (48.65%), Query Frame = 1

Query:  349 VTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALM-ELGMHCEDAIEMIRSKRKGSFNERQISYL 678
            V+ +VR+   +Y    F   G +     F DGS P  +I+ K+ +++ +       + G +AVHC AG GR   L+A  +M E G+   + +  +R  R GS    Q  YL
Sbjct:  238 VSTIVRLNAKNYDASKFTKAGFDHVDLFFIDGSTPSDEIMLKFIKVVDN-------TKGGVAVHCKAGLGRTGTLIACWMMKEYGLTAGECMGWLRVCRPGSVIGPQQPYL 341

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Celegans
Match: cdc-14 (Tyrosine-protein phosphatase cdc-14 [Source:UniProtKB/Swiss-Prot;Acc:P81299])

HSP 1 Score: 54.299 bits (129), Expect = 1.769e-7
Identity = 34/111 (30.63%), Postives = 54/111 (48.65%), Query Frame = 1

Query:  349 VTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALM-ELGMHCEDAIEMIRSKRKGSFNERQISYL 678
            V+ +VR+   +Y    F   G +     F DGS P  +I+ K+ +++ +       + G +AVHC AG GR   L+A  +M E G+   + +  +R  R GS    Q  YL
Sbjct:  238 VSTIVRLNAKNYDASKFTKAGFDHVDLFFIDGSTPSDEIMLKFIKVVDN-------TKGGVAVHCKAGLGRTGTLIACWMMKEYGLTAGECMGWLRVCRPGSVIGPQQPYL 341

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BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Fly
Match: PRL-1 (gene:FBgn0024734 transcript:FBtr0080857)

HSP 1 Score: 155.992 bits (393), Expect = 9.102e-45
Identity = 71/155 (45.81%), Postives = 103/155 (66.45%), Query Frame = 1

Query:  241 KPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            +P    I YK M FLI D PS   ++ +  E K+ NV  VVRVCE  Y+ +  +  GI +    F DG+ PP  ++++WF++LKD++  Q +    +AVHC+AG GRAPVLVA+AL+ELG+  E A+EMIR KR+G+ N +Q+S+L  Y+ K+RL
Sbjct:   11 RPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAFEDGTFPPQQVVDEWFEVLKDKY--QQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRDKRRGAINAKQLSFLEKYKPKARL 163

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Fly
Match: PRL-1 (gene:FBgn0024734 transcript:FBtr0332358)

HSP 1 Score: 155.992 bits (393), Expect = 9.102e-45
Identity = 71/155 (45.81%), Postives = 103/155 (66.45%), Query Frame = 1

Query:  241 KPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            +P    I YK M FLI D PS   ++ +  E K+ NV  VVRVCE  Y+ +  +  GI +    F DG+ PP  ++++WF++LKD++  Q +    +AVHC+AG GRAPVLVA+AL+ELG+  E A+EMIR KR+G+ N +Q+S+L  Y+ K+RL
Sbjct:   11 RPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAFEDGTFPPQQVVDEWFEVLKDKY--QQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRDKRRGAINAKQLSFLEKYKPKARL 163

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Fly
Match: PRL-1 (gene:FBgn0024734 transcript:FBtr0080856)

HSP 1 Score: 155.992 bits (393), Expect = 9.102e-45
Identity = 71/155 (45.81%), Postives = 103/155 (66.45%), Query Frame = 1

Query:  241 KPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            +P    I YK M FLI D PS   ++ +  E K+ NV  VVRVCE  Y+ +  +  GI +    F DG+ PP  ++++WF++LKD++  Q +    +AVHC+AG GRAPVLVA+AL+ELG+  E A+EMIR KR+G+ N +Q+S+L  Y+ K+RL
Sbjct:   11 RPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAFEDGTFPPQQVVDEWFEVLKDKY--QQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRDKRRGAINAKQLSFLEKYKPKARL 163

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Fly
Match: PRL-1 (gene:FBgn0024734 transcript:FBtr0332357)

HSP 1 Score: 155.992 bits (393), Expect = 9.102e-45
Identity = 71/155 (45.81%), Postives = 103/155 (66.45%), Query Frame = 1

Query:  241 KPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            +P    I YK M FLI D PS   ++ +  E K+ NV  VVRVCE  Y+ +  +  GI +    F DG+ PP  ++++WF++LKD++  Q +    +AVHC+AG GRAPVLVA+AL+ELG+  E A+EMIR KR+G+ N +Q+S+L  Y+ K+RL
Sbjct:   11 RPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAFEDGTFPPQQVVDEWFEVLKDKY--QQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRDKRRGAINAKQLSFLEKYKPKARL 163

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Fly
Match: FRG1 (gene:FBgn0036964 transcript:FBtr0074847)

HSP 1 Score: 102.064 bits (253), Expect = 4.913e-24
Identity = 75/180 (41.67%), Postives = 107/180 (59.44%), Query Frame = -2

Query:  985 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYCK 1524
            H +G+ P  +EI +   ++D K++ K+GY KY+ IE  G+   V    +A+G  EQW P+FEE ++ALL     F+S++  +          KV   E  ++R N    +  I+  P EE+    + E NYVKKFQ FQ  KM++++ D  EL++AK  G LHETLLDRR KMKADRYCK
Sbjct:   89 HNAGDGPDPEEIFTAFPINDRKVAFKSGYGKYLKIEKDGM---VTGRSEAVGGMEQWEPVFEEQRMALLSETGHFMSIDPQDDA--CVALRKKVGQHEICKVRSNASR-DVVIDTEPKEEKGDLGEVEKNYVKKFQKFQDKKMRINQNDVKELEQAKAQGSLHETLLDRRSKMKADRYCK 262

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Zebrafish
Match: ptp4a3a (protein tyrosine phosphatase 4A3a [Source:ZFIN;Acc:ZDB-GENE-040426-2220])

HSP 1 Score: 160.229 bits (404), Expect = 2.593e-46
Identity = 75/158 (47.47%), Postives = 99/158 (62.66%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    + YK+M FLI  +P+   +  F E+ K+  VT VVRVCE  Y +   +  GI +  W F DG+PPPS ++E W  LLK RF  +      +AVHC+AG GRAPVLVAVAL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVCYKNMRFLITHNPTNSTLSSFIEDLKKYGVTTVVRVCEITYDKTPLEKNGITVVDWPFDDGAPPPSKVVEDWLSLLKRRFIEEP--GCCVAVHCVAGLGRAPVLVAVALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    + YK+M FLI  +P+   +  F E+ K+  VT VVRVCE  Y +   +  GI +  W F DG+PPPS ++E W  LLK RF  +      +AVHC+AG GRAPVLVAVAL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVCYKNMRFLITHNPTNSTLSSFIEDLKKYGVTTVVRVCEITYDKTPLEKNGITVVDWPFDDGAPPPSKVVEDWLSLLKRRFIEEP--GCCVAVHCVAGLGRAPVLVAVALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    + YK+M FLI  +P+   +  F E+ K+  VT VVRVCE  Y +   +  GI +  W F DG+PPPS ++E W  LLK RF  +      +AVHC+AG GRAPVLVAVAL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVCYKNMRFLITHNPTNSTLSSFIEDLKKYGVTTVVRVCEITYDKTPLEKNGITVVDWPFDDGAPPPSKVVEDWLSLLKRRFIEEP--GCCVAVHCVAGLGRAPVLVAVALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Zebrafish
Match: ptp4a1 (protein tyrosine phosphatase 4A1 [Source:ZFIN;Acc:ZDB-GENE-041121-11])

HSP 1 Score: 158.303 bits (399), Expect = 2.190e-45
Identity = 77/162 (47.53%), Postives = 101/162 (62.35%), Query Frame = 1

Query:  220 KSARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            K AR   +P    I YK+M FLI  +P+   +H F EE K+  VT VVRVCE+ Y        GI +  W F DG+PP + I++ W  LL+ +F  +      IAVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:   11 KMAR-MNRPAPVEITYKNMRFLITHNPTNATLHKFIEELKKYGVTTVVRVCEATYDANLVVKEGIQVLDWPFDDGAPPSNQIVDDWLNLLRVKF--REEPGCCIAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLFYLEKYRPKMRL 169

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Zebrafish
Match: ptp4a1 (protein tyrosine phosphatase 4A1 [Source:ZFIN;Acc:ZDB-GENE-041121-11])

HSP 1 Score: 157.147 bits (396), Expect = 3.687e-45
Identity = 74/158 (46.84%), Postives = 98/158 (62.03%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    I YK+M FLI  +P+   +H F EE K+  VT VVRVCE+ Y        GI +  W F DG+PP + I++ W  LL+ +F  +      IAVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    3 RMNRPAPVEITYKNMRFLITHNPTNATLHKFIEELKKYGVTTVVRVCEATYDANLVVKEGIQVLDWPFDDGAPPSNQIVDDWLNLLRVKF--REEPGCCIAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLFYLEKYRPKMRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Xenopus
Match: ptp4a2 (protein tyrosine phosphatase type IVA, member 2 [Source:NCBI gene;Acc:549961])

HSP 1 Score: 156.377 bits (394), Expect = 8.509e-45
Identity = 71/157 (45.22%), Postives = 102/157 (64.97%), Query Frame = 1

Query:  235 FQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
              +P    I+++ M FLI  +P+   ++ F EE K+  VT +VRVC++ Y +   +  GI +  W F DG+PPP+ I++ W  LLK +F  +  +   IAVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    4 MNRPAPVEISHECMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIQVLDWPFDDGAPPPTQIVDDWLNLLKTKF--REEAGCCIAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Xenopus
Match: tcta (T cell leukemia translocation altered [Source:Xenbase;Acc:XB-GENE-954032])

HSP 1 Score: 155.606 bits (392), Expect = 2.288e-44
Identity = 73/158 (46.20%), Postives = 99/158 (62.66%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    I YK+M FLI  +P+   ++ F EE K+  VT +VRVCE+ Y     +  GI +  W F DG+PP + I++ W  LLK +F  +      IAVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    3 RMNRPAPVEITYKNMRFLITHNPTNATLNKFIEELKKYGVTTLVRVCEATYDTALVEKEGIQVLDWPFDDGAPPSNQIVDDWLNLLKMKF--REEPGCCIAVHCVAGLGRAPVLVALALIESGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Xenopus
Match: pfdn4 (prefoldin subunit 4 [Source:Xenbase;Acc:XB-GENE-856231])

HSP 1 Score: 155.221 bits (391), Expect = 3.330e-44
Identity = 71/158 (44.94%), Postives = 98/158 (62.03%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    + YK+M FLI  +P+   ++ F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP+ I++ W  LLK +F         +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RINRPAPVEVCYKNMRFLITHNPTNATMNTFIEDLKKYGATTVVRVCEITYDKTPLEKDGITVMDWPFDDGAPPPNKIVDDWLNLLKTKFC--EDPGCCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Xenopus
Match: cdh20 (cadherin 20 [Source:Xenbase;Acc:XB-GENE-1011620])

HSP 1 Score: 130.954 bits (328), Expect = 3.634e-34
Identity = 83/180 (46.11%), Postives = 112/180 (62.22%), Query Frame = -2

Query:  985 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYCK 1524
            HK  + PS  E  + + LSD++I+LK+GY KY+GI   GL   V    DA+G  EQW P+FE GK+ALL  NSCF+  N+   + ++   S      E ++IR          + +P E++    + E+NYVKKFQSFQ  K+K+S ED  +LKKA+K G  HETLLDRR K+KADRYCK
Sbjct:   83 HKDDDGPSPPEQFTAIKLSDSRIALKSGYGKYLGINSDGL---VIGRSDAIGAREQWEPVFENGKMALLASNSCFVGCNE---EGDLIAQSKTAGEGEMIKIRSCVERDGKSEDEIPKEDKGNVKQCEINYVKKFQSFQDNKLKVSLEDNKDLKKARKEGNFHETLLDRRSKLKADRYCK 256

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Xenopus
Match: cdh20 (cadherin 20 [Source:Xenbase;Acc:XB-GENE-1011620])

HSP 1 Score: 130.183 bits (326), Expect = 4.259e-34
Identity = 83/180 (46.11%), Postives = 112/180 (62.22%), Query Frame = -2

Query:  985 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYCK 1524
            HK  + PS  E  + + LSD++I+LK+GY KY+GI   GL   V    DA+G  EQW P+FE GK+ALL  NSCF+  N+   + ++   S      E ++IR          + +P E++    + E+NYVKKFQSFQ  K+K+S ED  +LKKA+K G  HETLLDRR K+KADRYCK
Sbjct:   74 HKDDDGPSPPEQFTAIKLSDSRIALKSGYGKYLGINSDGL---VIGRSDAIGAREQWEPVFENGKMALLASNSCFVGCNE---EGDLIAQSKTAGEGEMIKIRSCVERDGKSEDEIPKEDKGNVKQCEINYVKKFQSFQDNKLKVSLEDNKDLKKARKEGNFHETLLDRRSKLKADRYCK 247

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Mouse
Match: Ptp4a3 (protein tyrosine phosphatase 4a3 [Source:MGI Symbol;Acc:MGI:1277098])

HSP 1 Score: 160.229 bits (404), Expect = 2.684e-46
Identity = 73/158 (46.20%), Postives = 98/158 (62.03%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++Y+HM FLI  +PS   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  LLK +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++Y+HM FLI  +PS   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  LLK +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++Y+HM FLI  +PS   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  LLK +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++Y+HM FLI  +PS   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  LLK +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Mouse
Match: Ptp4a2 (protein tyrosine phosphatase 4a2 [Source:MGI Symbol;Acc:MGI:1277117])

HSP 1 Score: 157.918 bits (398), Expect = 1.922e-45
Identity = 71/157 (45.22%), Postives = 103/157 (65.61%), Query Frame = 1

Query:  235 FQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
              +P    I+Y++M FLI  +P+   ++ F EE K+  VT +VRVC++ Y +   +  GI++  W F DG+PPP+ I++ W  LLK +F  +      +AVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    1 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKF--REEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRL 155

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. UniProt/SwissProt
Match: sp|Q9D658|TP4A3_MOUSE (Protein tyrosine phosphatase type IVA 3 OS=Mus musculus OX=10090 GN=Ptp4a3 PE=1 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 1.877e-45
Identity = 73/158 (46.20%), Postives = 98/158 (62.03%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++Y+HM FLI  +PS   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  LLK +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. UniProt/SwissProt
Match: sp|O75365|TP4A3_HUMAN (Protein tyrosine phosphatase type IVA 3 OS=Homo sapiens OX=9606 GN=PTP4A3 PE=1 SV=2)

HSP 1 Score: 159.073 bits (401), Expect = 5.687e-45
Identity = 72/158 (45.57%), Postives = 98/158 (62.03%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    ++YKHM FLI  +P+   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP  ++E W  L+K +F     S   +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. UniProt/SwissProt
Match: sp|Q6P9X4|TP4A2_RAT (Protein tyrosine phosphatase type IVA 2 OS=Rattus norvegicus OX=10116 GN=Ptp4a2 PE=2 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 1.345e-44
Identity = 71/157 (45.22%), Postives = 103/157 (65.61%), Query Frame = 1

Query:  235 FQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
              +P    I+Y++M FLI  +P+   ++ F EE K+  VT +VRVC++ Y +   +  GI++  W F DG+PPP+ I++ W  LLK +F  +      +AVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    1 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKF--REEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRL 155

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. UniProt/SwissProt
Match: sp|O70274|TP4A2_MOUSE (Protein tyrosine phosphatase type IVA 2 OS=Mus musculus OX=10090 GN=Ptp4a2 PE=1 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 1.345e-44
Identity = 71/157 (45.22%), Postives = 103/157 (65.61%), Query Frame = 1

Query:  235 FQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
              +P    I+Y++M FLI  +P+   ++ F EE K+  VT +VRVC++ Y +   +  GI++  W F DG+PPP+ I++ W  LLK +F  +      +AVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    1 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKF--REEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRL 155

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. UniProt/SwissProt
Match: sp|Q12974|TP4A2_HUMAN (Protein tyrosine phosphatase type IVA 2 OS=Homo sapiens OX=9606 GN=PTP4A2 PE=1 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 1.345e-44
Identity = 71/157 (45.22%), Postives = 103/157 (65.61%), Query Frame = 1

Query:  235 FQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
              +P    I+Y++M FLI  +P+   ++ F EE K+  VT +VRVC++ Y +   +  GI++  W F DG+PPP+ I++ W  LLK +F  +      +AVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    1 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKF--REEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRL 155

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. TrEMBL
Match: A0A430QDS4 (Protein tyrosine phosphatase type IVA OS=Schistosoma bovis OX=6184 GN=DC041_0008269 PE=4 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 1.120e-64
Identity = 109/180 (60.56%), Postives = 133/180 (73.89%), Query Frame = 1

Query:  223 SARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRF---NTQSHSN------GSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRLYL-SQKCFIL 732
             AR  + P  T I +K M+F+IMDSPS+ NV  F EEC +LNV+DVVRVCE  Y  E F++ GI + HWEFSDGSPPP +IL +WF LL++RF   N  +H +      G IAVHCIAG+GRAPVLVAVALMELGM  EDAIE+IRSKRKG+FN+RQI YLT+Y A SRL   + +CFI+
Sbjct:    2 GARTLRLPIITDIKHKGMHFIIMDSPSKTNVPYFVEECSKLNVSDVVRVCEDRYPVEPFENAGICVHHWEFSDGSPPPENILTEWFTLLRNRFYGENNSTHDDQNHLVPGPIAVHCIAGYGRAPVLVAVALMELGMSSEDAIELIRSKRKGAFNDRQIHYLTNYHAHSRLRRHNHRCFIV 181

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. TrEMBL
Match: G4VB66 (TYR_PHOSPHATASE_2 domain-containing protein OS=Schistosoma mansoni OX=6183 GN=Smp_040550 PE=4 SV=1)

HSP 1 Score: 216.853 bits (551), Expect = 1.611e-64
Identity = 109/180 (60.56%), Postives = 133/180 (73.89%), Query Frame = 1

Query:  223 SARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRF---NTQSHSN------GSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRLYL-SQKCFIL 732
             AR  + P  T I +K M+F+IMDSPS+ NV  F EEC +LNV+DVVRVCE  Y  E F++ GI + HWEFSDGSPPP +IL +WF LL++RF   N  +H +      G IAVHCIAG+GRAPVLVAVALMELGM  EDAIE+IRSKRKG+FN+RQI YLT+Y A SRL   + +CFI+
Sbjct:    2 GARTLRLPIITDIKHKGMHFIIMDSPSKTNVPYFVEECSKLNVSDVVRVCEDRYPVEPFENAGICVHHWEFSDGSPPPENILTEWFTLLRNRFYGENNTAHVDQNHLVPGPIAVHCIAGYGRAPVLVAVALMELGMSSEDAIELIRSKRKGAFNDRQIHYLTNYHAHSRLRRHNHRCFIV 181

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. TrEMBL
Match: Q5DB62 (Protein tyrosine phosphatase type IVA 3 OS=Schistosoma japonicum OX=6182 GN=EWB00_006406 PE=2 SV=1)

HSP 1 Score: 214.542 bits (545), Expect = 1.127e-63
Identity = 106/179 (59.22%), Postives = 133/179 (74.30%), Query Frame = 1

Query:  223 SARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSN--------GSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRLYL-SQKCFIL 732
             AR  + P  T INYK M+F+IMDSPS+ NV  F EEC +L+V+DVVRVCE  Y  E F+  GI + HWEFSDGSPPP +IL +WF LL++RF  ++++         G +AVHCIAG+GRAPVLVAVALMELGM  EDAIE+IRSKRKG+FN+RQI YLT+Y + SRL   + +CFI+
Sbjct:    2 GARTLRLPIITDINYKGMHFIIMDSPSKTNVPYFVEECCKLHVSDVVRVCEDRYPVEPFEKAGICVHHWEFSDGSPPPENILTEWFTLLRNRFYGENNNQDDQSTLIPGPVAVHCIAGYGRAPVLVAVALMELGMSSEDAIELIRSKRKGAFNDRQIHYLTNYHSHSRLRRHNHRCFIV 180

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. TrEMBL
Match: A0A4V3SHA0 (TYR_PHOSPHATASE_2 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000379 PE=4 SV=1)

HSP 1 Score: 212.616 bits (540), Expect = 7.082e-63
Identity = 99/179 (55.31%), Postives = 129/179 (72.07%), Query Frame = 1

Query:  223 SARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQ--------SHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRLYL-SQKCFIL 732
            ++R  + P  T I YK +N +IMDSP++ +V  F EEC RL+V+D+VRVCE  Y  + F+  GI + HWEFSDGSPPP ++L  WF LL+ RF T+        + + G +AVHCIAG+GRAPVLVAVALMELGM C DAIE+IRSKRKG+FN+RQ++YLT Y  KSRL     +CF++
Sbjct:    2 NSRTLRLPVITTIEYKGINLIIMDSPTKSSVPYFVEECSRLHVSDIVRVCEDRYPTDEFEKSGIRVHHWEFSDGSPPPDNVLSDWFNLLRARFYTEPKTASSNATGAAGPVAVHCIAGYGRAPVLVAVALMELGMPCADAIELIRSKRKGAFNDRQLAYLTAYHPKSRLRRHGNRCFLM 180

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. TrEMBL
Match: A0A564XZ16 (TYR_PHOSPHATASE_2 domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS1470 PE=4 SV=1)

HSP 1 Score: 209.92 bits (533), Expect = 1.058e-61
Identity = 100/172 (58.14%), Postives = 126/172 (73.26%), Query Frame = 1

Query:  226 ARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRF-----------NTQSHSN-GSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            +R   KP  T + YK MNF+IMDSP+ D V  FA+EC RL+V+DV+RVCE  Y  E F++VGI + HWEF DGS PP DIL+KWF+LL+ RF           N+  H+  G +AVHC+AG+GRAPVLVAVALMELGM  +DAIE+IRSKRKG+FN+RQ+  L +YR+K RL
Sbjct:    3 SRQLLKPVITDVVYKGMNFIIMDSPAADTVQTFAKECSRLHVSDVIRVCEDKYPVEPFENVGIRVHHWEFEDGSFPPDDILDKWFELLRLRFYGSKKTTSGDGNSSDHATPGPVAVHCLAGYGRAPVLVAVALMELGMPNQDAIELIRSKRKGAFNDRQVESLRNYRSKGRL 174

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BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Cavefish
Match: ptp4a2b (protein tyrosine phosphatase type IVA 2 [Source:NCBI gene;Acc:103042327])

HSP 1 Score: 159.844 bits (403), Expect = 3.134e-46
Identity = 74/163 (45.40%), Postives = 102/163 (62.58%), Query Frame = 1

Query:  217 MKSARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            M    +  +P A  I Y+ M FLI  +P+   ++ F EE K+  V  +VRVCE+ Y +   +  GI +  W F DG+PPP+ I++ W  LLK +F  +      IAVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    1 MGRLANMNRPAAVEITYECMRFLITHNPTNSTLNKFTEELKKFEVNTLVRVCEATYDKAPVEREGIQVLDWPFDDGAPPPTQIVDDWLNLLKTKF--RDEPGCCIAVHCVAGLGRAPVLVALALIESGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRL 161

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Cavefish
Match: ptp4a2b (protein tyrosine phosphatase type IVA 2 [Source:NCBI gene;Acc:103042327])

HSP 1 Score: 159.844 bits (403), Expect = 3.548e-46
Identity = 73/158 (46.20%), Postives = 101/158 (63.92%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            +  +P A  I Y+ M FLI  +P+   ++ F EE K+  V  +VRVCE+ Y +   +  GI +  W F DG+PPP+ I++ W  LLK +F  +      IAVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    8 NMNRPAAVEITYECMRFLITHNPTNSTLNKFTEELKKFEVNTLVRVCEATYDKAPVEREGIQVLDWPFDDGAPPPTQIVDDWLNLLKTKF--RDEPGCCIAVHCVAGLGRAPVLVALALIESGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRL 163

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Cavefish
Match: ptp4a3a (protein tyrosine phosphatase type IVA 3-like [Source:NCBI gene;Acc:103031245])

HSP 1 Score: 158.303 bits (399), Expect = 1.341e-45
Identity = 71/158 (44.94%), Postives = 97/158 (61.39%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    + YK+M FLI  +P+   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP+ ++E W  LL+ RF         +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    3 RMNRPAPVEVRYKNMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPTKVVEDWLSLLRRRF--MEEPGCCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Cavefish
Match: ptp4a3b (protein tyrosine phosphatase type IVA 3 [Source:NCBI gene;Acc:103029087])

HSP 1 Score: 155.606 bits (392), Expect = 1.105e-44
Identity = 71/157 (45.22%), Postives = 98/157 (62.42%), Query Frame = 1

Query:  235 FQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
              +P    + YK+M FLI  +P+   +  F E+ K+   T VVRVCE  Y +   +  GI +  W F DG+PPP+ I++ W  LLK++F         +AVHC+AG GRAPVLVA+AL+E GM  EDAI+ IR KR+G+ N +Q++YL  YR K RL
Sbjct:    4 MNRPAPVEVCYKNMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEITYDKTPLEKDGITVMDWPFDDGAPPPTKIVDDWLSLLKNKFC--EDPGCCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Cavefish
Match: ptp4a1 (protein tyrosine phosphatase type IVA 1 [Source:NCBI gene;Acc:103037233])

HSP 1 Score: 154.836 bits (390), Expect = 2.153e-44
Identity = 72/158 (45.57%), Postives = 98/158 (62.03%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    I YK+M FLI  +P+   ++ F EE K+  VT VVRVCE+ Y        GI +  W F DG+PP + I++ W  LL+ +F  +      +AVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    3 RMNRPAPVEITYKNMRFLITHNPTNATLNKFIEELKKYGVTTVVRVCEATYDANLVAKEGIQVLDWPFDDGAPPSNQIVDDWLNLLRIKF--REEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLFYLEKYRPKMRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Sea Lamprey
Match: ptp4a1 (protein tyrosine phosphatase 4A1 [Source:ZFIN;Acc:ZDB-GENE-041121-11])

HSP 1 Score: 157.918 bits (398), Expect = 3.598e-46
Identity = 72/162 (44.44%), Postives = 102/162 (62.96%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRLYLSQ 717
               +P A  + YKHM FLI  +P+   ++ F EE K+ NVT VVRVCE  Y +   +  GI+++ W F DG+PP + I++ W  L K +F  +   +  I VHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+ N +Q+ YL  YR K +L   +
Sbjct:    6 RMNRPAAVEVTYKHMRFLITHNPTNVTLNKFIEELKKYNVTTVVRVCEVTYDKSPVEQQGISVFDWSFDDGAPPSNKIVDDWLNLCKTKF--RDEPDCCIGVHCVAGLGRAPVLVALALIESGMKYEDAVQFIRQKRRGAINSKQLLYLEKYRPKMKLRFKE 165

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Sea Lamprey
Match: cdc14ab (cell division cycle 14Ab [Source:NCBI gene;Acc:565969])

HSP 1 Score: 59.6918 bits (143), Expect = 2.821e-10
Identity = 41/131 (31.30%), Postives = 65/131 (49.62%), Query Frame = 1

Query:  337 KRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALME-LGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRLYLSQKCF 726
            ++  VT V+R+ +  Y    F D G+      F DGS P  DI+ K+ ++ +        + G++AVHC AG GR   L+A  LM+   +   +A+  IR  R GS    Q  +L  +R +S L+   + F
Sbjct:   45 RKNGVTTVIRLNKKIYDARRFTDAGLAHHDLFFPDGSSPSPDIVRKFCEICEG-------TRGAVAVHCKAGLGRTGTLIACYLMKHHRLTAAEAVAWIRICRPGSIIGPQQHFLLEWR-QSGLWAQGEAF 167

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Sea Lamprey
Match: ptp4a3a (protein tyrosine phosphatase 4A3a [Source:ZFIN;Acc:ZDB-GENE-040426-2220])

HSP 1 Score: 49.2914 bits (116), Expect = 2.616e-8
Identity = 22/60 (36.67%), Postives = 35/60 (58.33%), Query Frame = 1

Query:  241 KPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINL 420
            +P    + Y+ M FLI  +P+   ++ F EE K+ +VT VVRVCE  Y +   +  GI++
Sbjct:    6 RPAPVEVTYREMRFLITHNPNNTTLNKFIEELKQYSVTTVVRVCEVTYDKSPLEREGISV 65

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Yeast
Match: CDC14 (Protein phosphatase required for mitotic exit; required for rDNA segregation, cytokinesis, meiosis I spindle disassembly, environmental stress response; held in nucleolus by Cdc55p in early meiosis, liberated by FEAR and Mitotic Exit Network in anaphase, enabling it to effect a decrease in CDK/B-cyclin activity and mitotic exit; sequestered in metaphase II, released upon entry into anaphase II; human homolog CDC14A can complement thermosensitivity of yeast cdc14-1 mutant [Source:SGD;Acc:S000001924])

HSP 1 Score: 49.6766 bits (117), Expect = 8.130e-7
Identity = 36/121 (29.75%), Postives = 56/121 (46.28%), Query Frame = 1

Query:  289 MDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALM-ELGMHCEDAIEMIRSKRKG 648
            ++ P +  ++ FA      NV  VVR+    Y+++ F+D+GI      F DG+ P   I++ +    +    T     G IAVHC AG GR   L+   L+   G    + I  +R  R G
Sbjct:  207 LNQPFKSVLNFFANN----NVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVKNFVGAAE----TIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPG 319

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Nematostella
Match: EDO37167 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGK4])

HSP 1 Score: 141.739 bits (356), Expect = 3.907e-40
Identity = 65/144 (45.14%), Postives = 90/144 (62.50%), Query Frame = 1

Query:  274 MNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            M FLI D P+   +  + ++ K+ +   VVRVCE  Y+ E     GI +  W F DG+ PP  ++E W +LLK +F  +  S   +AVHC+AG GRAPVLVA+AL+E GM  EDA+E IR KR+G+ N +Q+SYL  Y+    L
Sbjct:    1 MKFLITDRPTNSTLPQYIQDLKKYDAHTVVRVCEPTYNTETLSKEGIIVLDWPFDDGAAPPKQLVEDWLKLLKGKFKERPGS--CVAVHCVAGLGRAPVLVALALIESGMKYEDAVEFIRRKRRGAINAKQLSYLERYKPTKLL 142

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Nematostella
Match: EDO44060 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWZ5])

HSP 1 Score: 100.908 bits (250), Expect = 4.875e-24
Identity = 74/185 (40.00%), Postives = 108/185 (58.38%), Query Frame = -2

Query:  985 SGEP-------PSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYCK 1518
            +GEP       P+  E+ + + +S+ K+++K+GY KY+ +   G    +    +A+G  EQ   +F+  KVAL   N CFLSV+       ++ +  K    E   IR +KP  + P     VE+       EL+YVKKFQSFQ  K+KLSKE++S LKKA+  G LHE +LDRREKMK+D++CK
Sbjct:   82 AGEPREDGVNSPAPVEVFTAVPVSEVKLAIKSGYGKYMSVNTMG---DITGRAEAIGPQEQLELLFDGDKVALQAYNGCFLSVSDSGS---LSASKKKAGEKEIFSIRADKPKSK-PKTDSQVEDEEDVTNLELSYVKKFQSFQDRKIKLSKEEQSNLKKARLDGRLHEEMLDRREKMKSDKFCK 259

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Nematostella
Match: EDO38271 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDJ9])

HSP 1 Score: 56.225 bits (134), Expect = 1.074e-8
Identity = 34/106 (32.08%), Postives = 54/106 (50.94%), Query Frame = 1

Query:  337 KRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALME-LGMHCEDAIEMIRSKRKGS 651
            K+ N++ VVR+ +  Y  + F D GI  +   F DGS P   I+ ++  + ++       + G IA+HC AG GR   L+A  LM+       ++I  +R  R GS
Sbjct:  201 KKHNISTVVRLNKKLYDAQRFTDHGIEHYDLFFIDGSVPSDMIVRRFLTIAEN-------AKGGIAIHCKAGLGRTGTLIACYLMKHYRFTAAESIGWLRVCRPGS 299

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Nematostella
Match: EDO38043 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE41])

HSP 1 Score: 47.7506 bits (112), Expect = 7.127e-6
Identity = 33/116 (28.45%), Postives = 51/116 (43.97%), Query Frame = 1

Query:  340 RLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALM-ELGMHCEDAIEMIRSKRKGSFNERQISYLTH 684
            RLN  D +      Y    F   G       F DG  P   I++++ ++L        H  G++A+HC AG GR   L+A  L+ +      +A+  +R  R GS +  Q  +L H
Sbjct:  226 RLNRDDNMIKYGLVYDARCFTANGFAHSDQYFEDGGIPTKAIVKRFTRIL-------DHCEGAVAIHCRAGLGRTGTLIACYLIKQYKFSAAEAVGWLRICRPGSVSSLQHCFLEH 334

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Medaka
Match: ptp4a2b (protein tyrosine phosphatase type IVA 2 [Source:NCBI gene;Acc:101164411])

HSP 1 Score: 156.377 bits (394), Expect = 6.244e-45
Identity = 72/163 (44.17%), Postives = 103/163 (63.19%), Query Frame = 1

Query:  217 MKSARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            M    +  +P A  I+Y  M FLI  +P+   ++ F E+ K+  V  +VRVCE+ Y +   +  GI++  W F DG+PPP+ I++ W +LL  +F  +      IAVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    1 MGRLANMNRPAAVEISYDCMTFLITHNPTNATLNKFTEDLKKFKVNTLVRVCEATYDKTPVEKEGIHVLDWPFDDGAPPPTQIVDDWLKLLNTKF--REEPGCCIAVHCVAGLGRAPVLVALALIESGMKYEDAVQYIRQKRRGAFNSKQLLYLEKYRPKMRL 161

[Close]

Query:  217 MKSARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
            M    +  +P A  I+Y  M FLI  +P+   ++ F E+ K+  V  +VRVCE+ Y +   +  GI++  W F DG+PPP+ I++ W +LL  +F  +      IAVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    1 MGRLANMNRPAAVEISYDCMTFLITHNPTNATLNKFTEDLKKFKVNTLVRVCEATYDKTPVEKEGIHVLDWPFDDGAPPPTQIVDDWLKLLNTKF--REEPGCCIAVHCVAGLGRAPVLVALALIESGMKYEDAVQYIRQKRRGAFNSKQLLYLEKYRPKMRL 161

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Medaka
Match: ptp4a1 (protein tyrosine phosphatase 4A1 [Source:NCBI gene;Acc:101157510])

HSP 1 Score: 155.992 bits (393), Expect = 1.042e-44
Identity = 74/158 (46.84%), Postives = 98/158 (62.03%), Query Frame = 1

Query:  232 HFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
               +P    I YK+M FLI  +P+   ++ F EE K+  VT VVRVCE+ Y        GI +  W F DG+PP + I++ W  LLK +F  +      IAVHC+AG GRAPVLVA+AL+E GM  EDA++ IR KR+G+FN +Q+ YL  YR K RL
Sbjct:    3 RMNRPAPVEITYKNMRFLITHNPTNATLNKFIEELKKYGVTTVVRVCEATYDAALVVKEGIQVLDWPFDDGAPPSNQIVDDWLNLLKLKF--REEPGCCIAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLFYLEKYRPKMRL 158

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Medaka
Match: ptp4a3b (protein tyrosine phosphatase type IVA 3 [Source:NCBI gene;Acc:101157004])

HSP 1 Score: 153.295 bits (386), Expect = 1.075e-43
Identity = 69/157 (43.95%), Postives = 101/157 (64.33%), Query Frame = 1

Query:  235 FQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRL 705
              +P    + +K+M FLI  +P+   +  F E+ KR  VT +VRVC+  Y +   +  GI ++ W F DG+ PP+ +++ W  LLK +F  Q      +AVHC+AG GRAPVLVA+AL+E GM  EDAI++IR KR+G+ N +Q++YL  YR+K RL
Sbjct:    5 MNRPAPVELCHKNMRFLITHNPTDSTLSSFVEDLKRYGVTLLVRVCDITYDKTTLEKDGITVFDWPFDDGAAPPNKLVDDWLSLLKKKF--QEDPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQLIRQKRRGAINSKQLTYLEKYRSKHRL 159

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Medaka
Match: ptp4a2a (protein tyrosine phosphatase type IVA 2-like [Source:NCBI gene;Acc:101163535])

HSP 1 Score: 139.428 bits (350), Expect = 2.304e-38
Identity = 65/159 (40.88%), Postives = 93/159 (58.49%), Query Frame = 1

Query:  235 FQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVRVCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSHSNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQISYLTHYRAKSRLYL 711
              +P    I+Y  + FLI  +P+   +  F E+ K   V  +VRVC + Y +   +  GI +  W F DGS PP  ++  W  LL+ +F  Q      +AVHC+AG GRAPVLVA+AL+E GM  EDA+ +IR KR+G+ N +Q+ YL  Y++K  L L
Sbjct:    1 MNRPAPVEISYDCLRFLITHNPTDAQMGKFIEDLKAFGVNTLVRVCAATYDKTPVEQEGIQVLDWPFDDGSAPPDQVVGDWLNLLQAKFKEQPGC--CVAVHCVAGLGRAPVLVALALIECGMEYEDAVHLIRQKRRGALNAKQLHYLEEYKSKLCLRL 157

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Planmine SMEST
Match: SMESG000078867.1 (SMESG000078867.1)

HSP 1 Score: 331.257 bits (848), Expect = 1.795e-111
Identity = 180/180 (100.00%), Postives = 180/180 (100.00%), Query Frame = -2

Query:  985 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYCK 1524
            HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK
Sbjct:   78 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK 257

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Planmine SMEST
Match: SMESG000078867.1 (SMESG000078867.1)

HSP 1 Score: 331.257 bits (848), Expect = 3.968e-111
Identity = 180/180 (100.00%), Postives = 180/180 (100.00%), Query Frame = -2

Query:  985 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYCK 1524
            HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK
Sbjct:   96 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK 275

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Planmine SMEST
Match: SMESG000010171.1 (SMESG000010171.1)

HSP 1 Score: 330.487 bits (846), Expect = 6.976e-110
Identity = 179/180 (99.44%), Postives = 179/180 (99.44%), Query Frame = -2

Query:  985 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYCK 1524
            HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVN INGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK
Sbjct:  163 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNNINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK 342

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Planmine SMEST
Match: SMESG000010171.1 (SMESG000010171.1)

HSP 1 Score: 330.487 bits (846), Expect = 9.489e-110
Identity = 179/180 (99.44%), Postives = 179/180 (99.44%), Query Frame = -2

Query:  985 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYCK 1524
            HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVN INGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK
Sbjct:  171 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNNINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK 350

[Close]

BLAST of Protein tyrosine phosphatase type IVA vs. Planmine SMEST
Match: SMESG000010171.1 (SMESG000010171.1)

HSP 1 Score: 330.487 bits (846), Expect = 1.320e-109
Identity = 179/180 (99.44%), Postives = 179/180 (99.44%), Query Frame = -2

Query:  985 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGXXXXXXXXXXXXXXXXKVGGLHETLLDRREKMKADRYCK 1524
            HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVN INGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK
Sbjct:  188 HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDAMGENEQWTPIFEEGKVALLGRNSCFLSVNNINGKIEVTCNSPKVESSEFLQIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDKSELKKAKKVGGLHETLLDRREKMKADRYCK 367

The following BLAST results are available for this feature:

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Human
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Celegans
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Fly
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Zebrafish
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Xenopus
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Mouse
BLAST of Protein tyrosine phosphatase type IVA vs. UniProt/SwissProt
BLAST of Protein tyrosine phosphatase type IVA vs. TrEMBL
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Cavefish
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Sea Lamprey
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Yeast
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Nematostella
BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Medaka
BLAST of Protein tyrosine phosphatase type IVA vs. Planmine SMEST

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PTP4A3	1.184e-45	45.57	protein tyrosine phosphatase 4A3 [Source:HGNC Symb...	[more]
PTP4A3	1.184e-45	45.57	protein tyrosine phosphatase 4A3 [Source:HGNC Symb...	[more]
PTP4A3	1.184e-45	45.57	protein tyrosine phosphatase 4A3 [Source:HGNC Symb...	[more]
PTP4A3	1.184e-45	45.57	protein tyrosine phosphatase 4A3 [Source:HGNC Symb...	[more]
PTP4A2	2.800e-45	45.22	protein tyrosine phosphatase 4A2 [Source:HGNC Symb...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
T19D2.2	1.118e-48	45.96	Putative prenylated protein tyrosine phosphatase ...	[more]
frg-1	1.267e-19	34.78	pep chromosome:WBcel235:III:12979162:12980163:1 ge...	[more]
cdc-14	1.622e-7	30.63	Tyrosine-protein phosphatase cdc-14 [Source:UniPr...	[more]
cdc-14	1.637e-7	30.63	Tyrosine-protein phosphatase cdc-14 [Source:UniPr...	[more]
cdc-14	1.769e-7	30.63	Tyrosine-protein phosphatase cdc-14 [Source:UniPr...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PRL-1	9.102e-45	45.81	gene:FBgn0024734 transcript:FBtr0080857	[more]
PRL-1	9.102e-45	45.81	gene:FBgn0024734 transcript:FBtr0332358	[more]
PRL-1	9.102e-45	45.81	gene:FBgn0024734 transcript:FBtr0080856	[more]
PRL-1	9.102e-45	45.81	gene:FBgn0024734 transcript:FBtr0332357	[more]
FRG1	4.913e-24	41.67	gene:FBgn0036964 transcript:FBtr0074847	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ptp4a3a	2.593e-46	47.47	protein tyrosine phosphatase 4A3a [Source:ZFIN;Acc...	[more]
ptp4a3a	2.593e-46	47.47	protein tyrosine phosphatase 4A3a [Source:ZFIN;Acc...	[more]
ptp4a3a	2.593e-46	47.47	protein tyrosine phosphatase 4A3a [Source:ZFIN;Acc...	[more]
ptp4a1	2.190e-45	47.53	protein tyrosine phosphatase 4A1 [Source:ZFIN;Acc:...	[more]
ptp4a1	3.687e-45	46.84	protein tyrosine phosphatase 4A1 [Source:ZFIN;Acc:...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ptp4a2	8.509e-45	45.22	protein tyrosine phosphatase type IVA, member 2 [S...	[more]
tcta	2.288e-44	46.20	T cell leukemia translocation altered [Source:Xenb...	[more]
pfdn4	3.330e-44	44.94	prefoldin subunit 4 [Source:Xenbase;Acc:XB-GENE-85...	[more]
cdh20	3.634e-34	46.11	cadherin 20 [Source:Xenbase;Acc:XB-GENE-1011620]	[more]
cdh20	4.259e-34	46.11	cadherin 20 [Source:Xenbase;Acc:XB-GENE-1011620]	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ptp4a3	2.684e-46	46.20	protein tyrosine phosphatase 4a3 [Source:MGI Symbo...	[more]
Ptp4a3	2.684e-46	46.20	protein tyrosine phosphatase 4a3 [Source:MGI Symbo...	[more]
Ptp4a3	2.684e-46	46.20	protein tyrosine phosphatase 4a3 [Source:MGI Symbo...	[more]
Ptp4a3	2.684e-46	46.20	protein tyrosine phosphatase 4a3 [Source:MGI Symbo...	[more]
Ptp4a2	1.922e-45	45.22	protein tyrosine phosphatase 4a2 [Source:MGI Symbo...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9D658\|TP4A3_MOUSE	1.877e-45	46.20	Protein tyrosine phosphatase type IVA 3 OS=Mus mus...	[more]
sp\|O75365\|TP4A3_HUMAN	5.687e-45	45.57	Protein tyrosine phosphatase type IVA 3 OS=Homo sa...	[more]
sp\|Q6P9X4\|TP4A2_RAT	1.345e-44	45.22	Protein tyrosine phosphatase type IVA 2 OS=Rattus ...	[more]
sp\|O70274\|TP4A2_MOUSE	1.345e-44	45.22	Protein tyrosine phosphatase type IVA 2 OS=Mus mus...	[more]
sp\|Q12974\|TP4A2_HUMAN	1.345e-44	45.22	Protein tyrosine phosphatase type IVA 2 OS=Homo sa...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A430QDS4	1.120e-64	60.56	Protein tyrosine phosphatase type IVA OS=Schistoso...	[more]
G4VB66	1.611e-64	60.56	TYR_PHOSPHATASE_2 domain-containing protein OS=Sch...	[more]
Q5DB62	1.127e-63	59.22	Protein tyrosine phosphatase type IVA 3 OS=Schisto...	[more]
A0A4V3SHA0	7.082e-63	55.31	TYR_PHOSPHATASE_2 domain-containing protein OS=Opi...	[more]
A0A564XZ16	1.058e-61	58.14	TYR_PHOSPHATASE_2 domain-containing protein OS=Hym...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ptp4a2b	3.134e-46	45.40	protein tyrosine phosphatase type IVA 2 [Source:NC...	[more]
ptp4a2b	3.548e-46	46.20	protein tyrosine phosphatase type IVA 2 [Source:NC...	[more]
ptp4a3a	1.341e-45	44.94	protein tyrosine phosphatase type IVA 3-like [Sour...	[more]
ptp4a3b	1.105e-44	45.22	protein tyrosine phosphatase type IVA 3 [Source:NC...	[more]
ptp4a1	2.153e-44	45.57	protein tyrosine phosphatase type IVA 1 [Source:NC...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ptp4a1	3.598e-46	44.44	protein tyrosine phosphatase 4A1 [Source:ZFIN;Acc:...	[more]
cdc14ab	2.821e-10	31.30	cell division cycle 14Ab [Source:NCBI gene;Acc:565...	[more]
ptp4a3a	2.616e-8	36.67	protein tyrosine phosphatase 4A3a [Source:ZFIN;Acc...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
CDC14	8.130e-7	29.75	Protein phosphatase required for mitotic exit; req...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO37167	3.907e-40	45.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44060	4.875e-24	40.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38271	1.074e-8	32.08	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38043	7.127e-6	28.45	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ptp4a2b	6.244e-45	44.17	protein tyrosine phosphatase type IVA 2 [Source:NC...	[more]
ptp4a2b	6.244e-45	44.17	protein tyrosine phosphatase type IVA 2 [Source:NC...	[more]
ptp4a1	1.042e-44	46.84	protein tyrosine phosphatase 4A1 [Source:NCBI gene...	[more]
ptp4a3b	1.075e-43	43.95	protein tyrosine phosphatase type IVA 3 [Source:NC...	[more]
ptp4a2a	2.304e-38	40.88	protein tyrosine phosphatase type IVA 2-like [Sour...	[more]

BLAST of Protein tyrosine phosphatase type IVA vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000078867.1	1.795e-111	100.00	SMESG000078867.1	[more]
SMESG000078867.1	3.968e-111	100.00	SMESG000078867.1	[more]
SMESG000010171.1	6.976e-110	99.44	SMESG000010171.1	[more]
SMESG000010171.1	9.489e-110	99.44	SMESG000010171.1	[more]
SMESG000010171.1	1.320e-109	99.44	SMESG000010171.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30034467 ID=SMED30034467|Name=Protein tyrosine phosphatase type IVA|organism=Schmidtea mediterranea sexual|type=transcript|length=1525bp
TAAAATTGACGCACTCAGTTTATTTTTTCACTTTTCCTTAATTTTTATAA
ATTATATTTTATTCAATATAGGTAAAAACAATTTTTAATTTTATAAAAAG
ATTTAATTTGTTAGTGATTTTAAGAAGTTATAAGTTTGTGTCAAAATTTT
AACTTTTAGTGCCTTTTGAAATTTATCAAGAATTAGAAGTCATAATTTTT
TTGTAAAGTATGACCCATGAAGTCTGCAAGACACTTTCAGAAACCATTTG
CTACACATATTAATTATAAACACATGAATTTTCTAATAATGGATTCTCCT
TCTCAAGATAACGTTCACATATTTGCAGAAGAATGTAAAAGATTAAACGT
TACTGATGTAGTTCGTGTTTGTGAATCACATTATAGTGAAGAAGCTTTCA
AAGATGTCGGTATTAATTTATGGCACTGGGAATTCAGTGATGGCTCACCT
CCACCAAGTGATATTTTAGAAAAATGGTTTCAGTTACTCAAAGATCGATT
TAACACCCAATCTCATTCCAATGGATCGATAGCGGTTCATTGTATTGCTG
GATTTGGTAGAGCTCCTGTGTTGGTGGCTGTTGCTTTAATGGAACTTGGA
ATGCATTGTGAAGACGCAATCGAAATGATACGAAGTAAACGCAAAGGTTC
CTTCAATGAACGTCAGATATCTTATTTAACTCATTATCGGGCCAAATCGA
GACTTTACCTATCCCAGAAGTGTTTTATATTATAATTGAAAATAATCAAC
GCAGTGAATCAAATTGACGCATATTCGTATCATCCTCAATTGGCCATTCT
TGTCAACCTGAGCCCTAATTATATATTTACAGTGATCGACCATTACTGAA
ACGATGATCTATCAATAAATTAAGATTGTATTAGTGTTGTAATGGCCTGT
TATATAATTGCGAATGAAAAAGATATTGTAAAATATTTTCCAGGCAATGA
TTTTTGAATTAAAAAATTGGAAAACAGATTTTTATTTACAATAACGATCA
GCTTTCATTTTTTCTCGTCTATCAAGTAATGTTTCATGTAAACCTCCAAC
TTTCTTTGCCTTCTTTAGTTCGCTTTTATCTTCTTTACTCAGTTTCATTT
TGCCTCCTTGAAAACTTTGGAATTTTTTAACGTAATTTAATTCTGATTTC
ATTGCCCCACTCCTTTCTTCGACTGGCAACAAATTTATTGGATCTTCGAA
TAATGGTTTGTTACATCTTATTTGAAGAAATTCAGATGATTCAACTTTTG
GTGAGTTGCATGTGACTTCTATTTTACCATTTATCTTATTTACGCTTAAA
AAACACGAATTTCTTCCTAGTAGAGCAACTTTACCTTCTTCAAAAATCGG
TGTCCATTGTTCATTCTCACCCATGGCATCTCTCACGGCATTAACTGTAT
TATTTAGGCCTTTCATTTCAATACCAACATACTTGTTGTATCCAGTTTTC
AAAGAAATCTTTGTATCTGAAAGGACCATACATGATAGGATTTCATCTTC
TGATGGTGGCTCACCACTTTTATGC

protein sequence of SMED30034467-orf-1

>SMED30034467-orf-1 ID=SMED30034467-orf-1|Name=SMED30034467-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=173bp
MKSARHFQKPFATHINYKHMNFLIMDSPSQDNVHIFAEECKRLNVTDVVR
VCESHYSEEAFKDVGINLWHWEFSDGSPPPSDILEKWFQLLKDRFNTQSH
SNGSIAVHCIAGFGRAPVLVAVALMELGMHCEDAIEMIRSKRKGSFNERQ
ISYLTHYRAKSRLYLSQKCFIL*

protein sequence of SMED30034467-orf-2

>SMED30034467-orf-2 ID=SMED30034467-orf-2|Name=SMED30034467-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=181bp
HKSGEPPSEDEILSCMVLSDTKISLKTGYNKYVGIEMKGLNNTVNAVRDA
MGENEQWTPIFEEGKVALLGRNSCFLSVNKINGKIEVTCNSPKVESSEFL
QIRCNKPLFEDPINLLPVEERSGAMKSELNYVKKFQSFQGGKMKLSKEDK
SELKKAKKVGGLHETLLDRREKMKADRYCK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0000101	muscle cell
PLANA:0000142	posterior region of the whole animal
PLANA:0002109	X1 cell

Vocabulary: **biological process**
Term	Definition
GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation

Vocabulary: **molecular function**
Term	Definition
GO:0016791	phosphatase activity
GO:0008138	protein tyrosine/serine/threonine phosphatase activity
GO:0004725	protein tyrosine phosphatase activity
GO:0016787	hydrolase activity

Vocabulary: **INTERPRO**
Term	Definition
IPR003595	Tyr_Pase_cat
IPR029021	Prot-tyrosine_phosphatase-like
IPR000340	Dual-sp_phosphatase_cat-dom
IPR000387	TYR_PHOSPHATASE_dom
IPR010414	FRG1
IPR008999	Actin-crosslinking

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003595	Protein-tyrosine phosphatase, catalytic	SMART	SM00404	ptp_7	coord: 64..160 e-value: 2.1E-4 score: 29.0
IPR000340	Dual specificity phosphatase, catalytic domain	PFAM	PF00782	DSPc	coord: 43..157 e-value: 5.6E-10 score: 39.2
IPR029021	Protein-tyrosine phosphatase-like	GENE3D	G3DSA:3.90.190.10		coord: 3..168 e-value: 5.6E-47 score: 161.5
IPR029021	Protein-tyrosine phosphatase-like	SUPERFAMILY	SSF52799	(Phosphotyrosine protein) phosphatases II	coord: 11..158
None	No IPR available	PANTHER	PTHR23339	TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE	coord: 5..166
None	No IPR available	PANTHER	PTHR23339:SF65	PROTEIN TYROSINE PHOSPHATASE TYPE IVA 2	coord: 5..166
None	No IPR available	CDD	cd14500	PTP-IVa	coord: 10..163 e-value: 7.50949E-90 score: 257.149
IPR000387	Tyrosine specific protein phosphatases domain	PROSITE	PS50056	TYR_PHOSPHATASE_2	coord: 85..153 score: 15.213