ribosome maturation protein SBDS

Overview
Nameribosome maturation protein SBDS
Smed IDSMED30034427
Length (bp)1327
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ribosome maturation protein SBDS (SMED30034427) t-SNE clustered cells

Violin plots show distribution of expression levels for ribosome maturation protein SBDS (SMED30034427) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ribosome maturation protein SBDS (SMED30034427) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ribosome maturation protein SBDS (SMED30034427) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30034427

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30034427h1SMcG0016678 Contig39432uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30034427h1SMcG0016678 Contig39432newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30034427h1SMcG0016678 dd_Smed_v4_4125_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Human
Match: SBDS (SBDS ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:19440])

HSP 1 Score: 172.94 bits (437), Expect = 1.773e-50
Identity = 103/256 (40.23%), Postives = 153/256 (59.77%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI-SSDHKF 846
            M++FTPTNQ RLTNV+VV++     +   RFEIACY NKV+ WR  +E  ++EVLQ+  V+VNVSK ++A KE L  AF T +  +ICK IL KGE+Q+++KER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K NKS KQQ+L+VI+ LK K +I         I+ V + +    K         VI        L+I  + +PG +    +L K+  + K ++E+  + D+   D KF
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKL---KPLIKVIESEDYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLKDVEEGDEKF 249
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Human
Match: SBDS (SBDS ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:19440])

HSP 1 Score: 172.17 bits (435), Expect = 2.854e-50
Identity = 103/256 (40.23%), Postives = 152/256 (59.38%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI-SSDHKF 846
            M++FTPTNQ RLTNV+VV++     +   RFEIACY NKV+ WR   E  ++EVLQ+  V+VNVSK ++A KE L  AF T +  +ICK IL KGE+Q+++KER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K NKS KQQ+L+VI+ LK K +I         I+ V + +    K         VI        L+I  + +PG +    +L K+  + K ++E+  + D+   D KF
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KRAGKRFEIACYKNKVVGWRSAWEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKL---KPLIKVIESEDYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLKDVEEGDEKF 249
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Human
Match: SBDS (SBDS ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:19440])

HSP 1 Score: 94.7449 bits (234), Expect = 3.041e-23
Identity = 44/81 (54.32%), Postives = 58/81 (71.60%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQT 336
            M++FTPTNQ RLTNV+VV++     +   RFEIACY NKV+ WR  +E  ++EVLQ+  V+VNVSK ++A KE L  AF T
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGT 77
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Celegans
Match: sbds-1 (Ribosome maturation protein SBDS [Source:UniProtKB/Swiss-Prot;Acc:Q23202])

HSP 1 Score: 173.326 bits (438), Expect = 4.485e-51
Identity = 98/245 (40.00%), Postives = 150/245 (61.22%), Query Frame = 1 
Query:  106 TPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI 828
            TPTNQK LTNV+VV++     K   RFEIACY NKV+ WR K E  I+EVLQ+  V+ NVSK +++ KE L  AF   + L+ICK ILDKG+LQ++EKER    +   K+V++++ S  +NP TK   P  VI+K +++ H +LK N+S+KQQ+LD I   K +  + I+ A   + + +P K+ K+V  +L     +V  +  QD  L++  + EPG++    DL +   +    +E+  + D+
Sbjct:    7 TPTNQKVLTNVAVVRM----KKTGKRFEIACYKNKVVNWRNKSEKDIDEVLQTHTVFSNVSKGQLSKKEELIAAFGIEDQLEICKIILDKGDLQVSEKERQAASDQSLKEVSQLIASMVVNPETKRPVPPSVIDKALQEMHFSLKPNRSSKQQALDAIP--KLRETLKIERAKMKIRVAIPTKEAKSVHTKLKTLFSDVEVDDWQDGSLEMVGLIEPGSFRALDDLVRNETKGHGRLEILSLKDV 245
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Fly
Match: CG8549 (gene:FBgn0035714 transcript:FBtr0076943)

HSP 1 Score: 163.696 bits (413), Expect = 3.295e-47
Identity = 87/228 (38.16%), Postives = 139/228 (60.96%), Query Frame = 1 
Query:  100 LFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKA-VKRELLNYSENVISETLQDHDLKIEAVFEPGNYDLFKE 780
            +FTPTNQ RLTNV++V+L     K   RFEIACY NKV++WR   E  I+EVLQ+  V+ NVSK + A K+ L++AF   +  +ICK IL KGELQ++EKER   ++T    +   V +  +NP T+  +P+ +IEK +KD H ++K+N++ KQ +L+ I++L  K  +PI+ +   + ++   K+    +K  ++  +  V  E   +  L +  + +PG Y +  E
Sbjct:    4 IFTPTNQIRLTNVAIVRL----KKGGKRFEIACYKNKVLSWRSNSEKDIDEVLQTHTVFTNVSKGQAAKKDELQKAFNKTDETEICKEILSKGELQVSEKERQSCLDTQLNSIVNSVAALCVNPETRRPYPASIIEKSLKDAHFSVKMNRNTKQNTLEAIKIL--KDHMPIERSRMKLRVSFAGKEGGGKLKESVVKLANAVEHEEWDEATLHLTLLIDPGQYRVIDE 225
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Fly
Match: CG8549 (gene:FBgn0035714 transcript:FBtr0330060)

HSP 1 Score: 163.696 bits (413), Expect = 3.295e-47
Identity = 87/228 (38.16%), Postives = 139/228 (60.96%), Query Frame = 1 
Query:  100 LFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKA-VKRELLNYSENVISETLQDHDLKIEAVFEPGNYDLFKE 780
            +FTPTNQ RLTNV++V+L     K   RFEIACY NKV++WR   E  I+EVLQ+  V+ NVSK + A K+ L++AF   +  +ICK IL KGELQ++EKER   ++T    +   V +  +NP T+  +P+ +IEK +KD H ++K+N++ KQ +L+ I++L  K  +PI+ +   + ++   K+    +K  ++  +  V  E   +  L +  + +PG Y +  E
Sbjct:    4 IFTPTNQIRLTNVAIVRL----KKGGKRFEIACYKNKVLSWRSNSEKDIDEVLQTHTVFTNVSKGQAAKKDELQKAFNKTDETEICKEILSKGELQVSEKERQSCLDTQLNSIVNSVAALCVNPETRRPYPASIIEKSLKDAHFSVKMNRNTKQNTLEAIKIL--KDHMPIERSRMKLRVSFAGKEGGGKLKESVVKLANAVEHEEWDEATLHLTLLIDPGQYRVIDE 225
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Zebrafish
Match: sbds (SBDS ribosome maturation factor [Source:ZFIN;Acc:ZDB-GENE-040426-1116])

HSP 1 Score: 182.956 bits (463), Expect = 1.354e-54
Identity = 105/249 (42.17%), Postives = 156/249 (62.65%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI 828
            M++FTPTNQ RLTNV+VV++     K   RFEIACY NKV++WR   E  ++EVLQ+  V+VNVSK ++A KE L  AF T ++ +ICK IL KGELQ+++KER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K NKS KQQ+L+VI+ L  K  I I  A   +   +P K  K +K +L    + V +E   D  L++  + +PG +    +L +   + K T+E+  + D+
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KKGGKRFEIACYKNKVMSWRSGAEKDLDEVLQTNTVFVNVSKGQVAKKEDLSNAFGTDDLTEICKQILSKGELQVSDKERQSQLEQMFRDIATIVAEKCVNPETKRPYTVNLIERAMKDIHFSVKANKSTKQQALEVIKQL--KESIQIQRAHMRLRFVLPAKDGKRLKEKLKPLIKAVENEDFDDQ-LEMVCLIDPGCFRDIDELIRCETKGKGTLEVLSLKDV 242
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Zebrafish
Match: sbds (SBDS ribosome maturation factor [Source:ZFIN;Acc:ZDB-GENE-040426-1116])

HSP 1 Score: 178.333 bits (451), Expect = 1.292e-52
Identity = 106/256 (41.41%), Postives = 157/256 (61.33%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIE-------AVFEPGNY----DLFKENFETKCTIELSKILDI 828
            M++FTPTNQ RLTNV+VV++     K   RFEIACY NKV++WR   E  ++EVLQ+  V+VNVSK ++A KE L  AF T ++ +ICK IL KGELQ+++KER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K NKS KQQ+L+VI+ L  K  I I  A   +   +P K  K +K +L    + V +E   D  L++E        + +PG +    +L +   + K T+E+  + D+
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KKGGKRFEIACYKNKVMSWRSGAEKDLDEVLQTNTVFVNVSKGQVAKKEDLSNAFGTDDLTEICKQILSKGELQVSDKERQSQLEQMFRDIATIVAEKCVNPETKRPYTVNLIERAMKDIHFSVKANKSTKQQALEVIKQL--KESIQIQRAHMRLRFVLPAKDGKRLKEKLKPLIKAVENEDFDDQ-LEMELFLLFQVCLIDPGCFRDIDELIRCETKGKGTLEVLSLKDV 249
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Xenopus
Match: sbds (SBDS ribosome assembly guanine nucleotide exchange factor [Source:NCBI gene;Acc:448365])

HSP 1 Score: 176.407 bits (446), Expect = 7.443e-52
Identity = 107/256 (41.80%), Postives = 160/256 (62.50%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI-SSDHKF 846
            M++FTPTNQ RLTNV+VV++     K   RFEIACY NKV++WR   E  ++EVLQ+  V++NVSK ++A KE L ++F T +  +ICK IL KGELQ++EKER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K  KS KQQ+LDVI+ LK    + I+ A   +   +P K  K +K +L    ++  SE   D +L+I  + +PG +    +L +   + K T+E+  + D+   D KF
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KKGGKRFEIACYKNKVMSWRSGAEKDLDEVLQTHSVFMNVSKGQVAKKEDLLKSFGTEDPTEICKQILSKGELQVSEKERSTQLEQMFRDIATIVADKCVNPETKRPYTVNLIERAMKDIHYSVKATKSTKQQALDVIKQLKET--MQIERAHMRLRFILPAKDGKKLKEKLKPLIKHTESENF-DQELEIVCLIDPGCFREIDELIRCETKGKGTLEVLSLKDVEEGDEKF 249
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Mouse
Match: Sbds (SBDS ribosome maturation factor [Source:MGI Symbol;Acc:MGI:1913961])

HSP 1 Score: 171.785 bits (434), Expect = 3.089e-50
Identity = 105/256 (41.02%), Postives = 160/256 (62.50%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI-SSDHKF 846
            M++FTPTNQ RLTNV+VV++     +   RFEIACY NKV+ WR  +E  ++EVLQ+  V+VNVSK ++A KE L  AF T +  +ICK IL KGE+Q+++KER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K NKS KQQ+L+VI+ LK K  + I+ A   +   +P  + K +K +L    + V SE      L+I  + +PG +    +L K+  + + ++E+  + D+   D KF
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KRGGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKPNKSTKQQALEVIKQLKEK--MKIERAHMRLRFILPVNEGKKLKEKLKPLMKVVESEDY-SQQLEIVCLIDPGCFREIDELIKKETKGRGSLEVLSLKDVEEGDEKF 249
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Mouse
Match: Sbds (SBDS ribosome maturation factor [Source:MGI Symbol;Acc:MGI:1913961])

HSP 1 Score: 114.775 bits (286), Expect = 8.689e-30
Identity = 60/124 (48.39%), Postives = 87/124 (70.16%), Query Frame = 1 
Query:  235 ETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEI 606
            E  ++EVLQ+  V+VNVSK ++A KE L  AF T +  +ICK IL KGE+Q+++KER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K NKS KQQ+L+VI+ LK K +I
Sbjct:    7 EKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKPNKSTKQQALEVIKQLKEKMKI 130
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Mouse
Match: Sbds (SBDS ribosome maturation factor [Source:MGI Symbol;Acc:MGI:1913961])

HSP 1 Score: 58.151 bits (139), Expect = 5.848e-11
Identity = 26/44 (59.09%), Postives = 33/44 (75.00%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWR 225
            M++FTPTNQ RLTNV+VV++     +   RFEIACY NKV+ WR
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KRGGKRFEIACYKNKVVGWR 40
[Close]
BLAST of ribosome maturation protein SBDS vs. UniProt/SwissProt
Match: sp|A5D8M6|SBDS_XENLA (Ribosome maturation protein SBDS OS=Xenopus laevis OX=8355 GN=sbds PE=2 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 7.701e-52
Identity = 109/256 (42.58%), Postives = 160/256 (62.50%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI-SSDHKF 846
            M++FTPTNQ RLTNV+VV++     K   RFEIACY NKV++WR   E  ++EVLQ+  V++NVSK + A KE L +AF T +  +ICK IL KGELQ++EKER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K  KS KQQ+LDVI+ LK    + I+ A   +   VP K  K +K +L    +++ SE   D +L+I  + +PG +    +L +   + K T+E+  + D+   D KF
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KKGGKRFEIACYKNKVMSWRSGAEKDLDEVLQTHSVFMNVSKGQGAKKEDLLKAFGTEDQTEICKQILSKGELQVSEKERSTQLEQMFRDIATIVADKCVNPETKRPYTVNLIERAMKDIHYSVKATKSTKQQALDVIKQLKET--MQIERAHMRLRFIVPAKDGKKLKEKLKPLIKHIESENF-DQELEIVCLIDPGCFREIDELIRCETKGKGTLEVLSLKDVEEGDEKF 249
[Close]
BLAST of ribosome maturation protein SBDS vs. UniProt/SwissProt
Match: sp|Q6DIT8|SBDS_XENTR (Ribosome maturation protein SBDS OS=Xenopus tropicalis OX=8364 GN=sbds PE=2 SV=1)

HSP 1 Score: 176.407 bits (446), Expect = 3.943e-51
Identity = 107/256 (41.80%), Postives = 160/256 (62.50%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI-SSDHKF 846
            M++FTPTNQ RLTNV+VV++     K   RFEIACY NKV++WR   E  ++EVLQ+  V++NVSK ++A KE L ++F T +  +ICK IL KGELQ++EKER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K  KS KQQ+LDVI+ LK    + I+ A   +   +P K  K +K +L    ++  SE   D +L+I  + +PG +    +L +   + K T+E+  + D+   D KF
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KKGGKRFEIACYKNKVMSWRSGAEKDLDEVLQTHSVFMNVSKGQVAKKEDLLKSFGTEDPTEICKQILSKGELQVSEKERSTQLEQMFRDIATIVADKCVNPETKRPYTVNLIERAMKDIHYSVKATKSTKQQALDVIKQLKET--MQIERAHMRLRFILPAKDGKKLKEKLKPLIKHTESENF-DQELEIVCLIDPGCFREIDELIRCETKGKGTLEVLSLKDVEEGDEKF 249
[Close]
BLAST of ribosome maturation protein SBDS vs. UniProt/SwissProt
Match: sp|Q23202|SBDS_CAEEL (Ribosome maturation protein SBDS OS=Caenorhabditis elegans OX=6239 GN=sbds-1 PE=3 SV=2)

HSP 1 Score: 173.326 bits (438), Expect = 5.706e-50
Identity = 98/245 (40.00%), Postives = 150/245 (61.22%), Query Frame = 1 
Query:  106 TPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI 828
            TPTNQK LTNV+VV++     K   RFEIACY NKV+ WR K E  I+EVLQ+  V+ NVSK +++ KE L  AF   + L+ICK ILDKG+LQ++EKER    +   K+V++++ S  +NP TK   P  VI+K +++ H +LK N+S+KQQ+LD I   K +  + I+ A   + + +P K+ K+V  +L     +V  +  QD  L++  + EPG++    DL +   +    +E+  + D+
Sbjct:    7 TPTNQKVLTNVAVVRM----KKTGKRFEIACYKNKVVNWRNKSEKDIDEVLQTHTVFSNVSKGQLSKKEELIAAFGIEDQLEICKIILDKGDLQVSEKERQAASDQSLKEVSQLIASMVVNPETKRPVPPSVIDKALQEMHFSLKPNRSSKQQALDAIP--KLRETLKIERAKMKIRVAIPTKEAKSVHTKLKTLFSDVEVDDWQDGSLEMVGLIEPGSFRALDDLVRNETKGHGRLEILSLKDV 245
[Close]
BLAST of ribosome maturation protein SBDS vs. UniProt/SwissProt
Match: sp|Q5RAZ2|SBDS_PONAB (Ribosome maturation protein SBDS OS=Pongo abelii OX=9601 GN=SBDS PE=2 SV=1)

HSP 1 Score: 172.94 bits (437), Expect = 8.513e-50
Identity = 103/256 (40.23%), Postives = 153/256 (59.77%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI-SSDHKF 846
            M++FTPTNQ RLTNV+VV++     +   RFEIACY NKV+ WR  +E  ++EVLQ+  V+VNVSK ++A KE L  AF T +  +ICK IL KGE+Q+++KER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K NKS KQQ+L+VI+ LK K +I         I+ V + +    K         VI        L+I  + +PG +    +L K+  + K ++E+  + D+   D KF
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKL---KPLIKVIESEDYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLKDVEEGDEKF 249
[Close]
BLAST of ribosome maturation protein SBDS vs. UniProt/SwissProt
Match: sp|Q9Y3A5|SBDS_HUMAN (Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4)

HSP 1 Score: 172.94 bits (437), Expect = 8.513e-50
Identity = 103/256 (40.23%), Postives = 153/256 (59.77%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDI-SSDHKF 846
            M++FTPTNQ RLTNV+VV++     +   RFEIACY NKV+ WR  +E  ++EVLQ+  V+VNVSK ++A KE L  AF T +  +ICK IL KGE+Q+++KER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K NKS KQQ+L+VI+ LK K +I         I+ V + +    K         VI        L+I  + +PG +    +L K+  + K ++E+  + D+   D KF
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKL---KPLIKVIESEDYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLKDVEEGDEKF 249
[Close]
BLAST of ribosome maturation protein SBDS vs. TrEMBL
Match: A0A4Z2DM93 (Ribosome maturation protein OS=Schistosoma japonicum OX=6182 GN=EWB00_010964 PE=4 SV=1)

HSP 1 Score: 203.756 bits (517), Expect = 2.339e-58
Identity = 117/255 (45.88%), Postives = 162/255 (63.53%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISET-LQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDISSDHK 843
            MALFTPTNQKRLTNVSVV+L     K   R+E+ACYPNKV  WR KLET +NEVLQ+  V+ NVSK + A+K+ +   F+T +  +I K+IL+ GELQLTEKERLV  + L +DVAKIV+ + +NP     +   ++EKM+KDCHI+LK NKSAKQ +L+VI+ L+    + I  ++  V IT+ +   + V   LL    ++I +    D   ++ AV EPG Y     L ++  + K  IE+S    I  +HK
Sbjct:    1 MALFTPTNQKRLTNVSVVRL----KKGGSRYELACYPNKVQPWRDKLETNLNEVLQAHCVFTNVSKGQFANKKEMFAHFRTEDEREIIKSILEHGELQLTEKERLVGQQALFRDVAKIVSERCVNPENNRAYTVTMVEKMMKDCHISLKANKSAKQHALEVIKQLRSAPGLKIAPSMMEVNITMQKDISEPVIERLLQLCSSIIRQGESSDGLFELIAVVEPGKYCLIETLLQKEIKGKYCIEISD--GIKCNHK 249
[Close]
BLAST of ribosome maturation protein SBDS vs. TrEMBL
Match: A0A183MN08 (Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS17433 PE=4 SV=1)

HSP 1 Score: 203.756 bits (517), Expect = 2.476e-58
Identity = 113/245 (46.12%), Postives = 157/245 (64.08%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDL-KIEAVFEPGNYD----LFKENFETKCTIELS 813
            MALFTPTNQKRLTN+SVV+L     K  +R+E+ACYPNKV AWR KLET ++EVLQ+  V+ NVSK + A+K+ +   F+T +   I KTIL+ GELQLTEKERLV  + L +DVAKIV+ + +NP     +   +IEKM+KDCHI+LK NKSAKQ +L+VI+ L+      I  ++  V IT+ +   ++V   LL    +++ ++     L  + AV EP  Y     L     + K +IE+S
Sbjct:    1 MALFTPTNQKRLTNISVVRL----KKGGNRYELACYPNKVQAWRDKLETNLDEVLQAHCVFTNVSKGQFANKKEMYVHFRTEDERQIIKTILEHGELQLTEKERLVGQQALFRDVAKIVSERCVNPENNRAYTVTMIEKMMKDCHISLKANKSAKQHALEVIKQLRSAPGFKIAPSMMEVNITIQKDSCESVIERLLQLCNDIVQQSESPDGLYDLTAVVEPEKYGSIETLLHNEIKGKYSIEIS 241
[Close]
BLAST of ribosome maturation protein SBDS vs. TrEMBL
Match: Q5DG22 (SJCHGC02313 protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 203.371 bits (516), Expect = 4.385e-58
Identity = 117/255 (45.88%), Postives = 162/255 (63.53%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISET-LQDHDLKIEAVFEPGNY----DLFKENFETKCTIELSKILDISSDHK 843
            MALFTPTNQKRLTNVSVV+L     K   R+E+ACYPNKV  WR KLET +NEVLQ+  V+ NVSK + A+K+ +   F+T +  +I K+IL+ GELQLTEKERLV  + L +DVAKIV+ + +NP     +   ++EKM+KDCHI+LK NKSAKQ +L+VI+ L+    + I  ++  V IT+ +   + V   LL    ++I +    D   ++ AV EPG Y     L ++  + K  IE+S    I  +HK
Sbjct:    1 MALFTPTNQKRLTNVSVVRL----KKGGSRYELACYPNKVQPWRDKLETNLNEVLQAHCVFTNVSKGQFANKKEMFAHFRTEDEREIIKSILEHGELQLTEKERLVGQQALFRDVAKIVSERCVNPENNRAYTVTMVEKMMKDCHISLKANKSAKQHALEVIKQLRSAPGLKIAPSMMEVNITMLKDISEPVIERLLQLCSSIIRQGESSDGLFELIAVVEPGKYCLIETLLQKEIKGKYCIEISD--GIKCNHK 249
[Close]
BLAST of ribosome maturation protein SBDS vs. TrEMBL
Match: A0A4S2LMB4 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006207 PE=4 SV=1)

HSP 1 Score: 203.756 bits (517), Expect = 4.928e-58
Identity = 113/265 (42.64%), Postives = 167/265 (63.02%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVI--SETLQDHDLKIEAVFEPGNYDLFKENFETKCTIELSKILDISSDHKFVQESVNLKNESD 882
            MALFTPTNQKRLTNVSVV+L     K  +R+E+ACYPNKV AWR +LET ++EVLQ + V+ NVSK + A+K+ + + F+T N +DI K IL++GELQLTEKER V+ ++L +DVAK+V+ + +NP T   +   +IEKM+KDCHI+LK NK+AKQ +L+VI+ L+      I  A+  V++++    +  VK  +L    +VI   +     + ++  V EP  Y   +    ++  I+    ++I  + K V      K  SD
Sbjct:    1 MALFTPTNQKRLTNVSVVRL----KKGGNRYELACYPNKVRAWRDRLETNLDEVLQIQCVFTNVSKGQFANKKEMFQVFRTENEIDIIKLILEQGELQLTEKERSVEQQSLFRDVAKMVSERCVNPETNRAYTVTMIEKMMKDCHISLKANKTAKQHALEVIKHLRSTDGFKIAPAMMEVVVSIDSTVVPLVKDSVLQLCTDVIRQGQNADTGNYELTVVIEPEKYGAIEALLHSE--IKGKYCIEIVGNTKHVTHRPATKTASD 259
[Close]
BLAST of ribosome maturation protein SBDS vs. TrEMBL
Match: T1EY72 (Uncharacterized protein OS=Helobdella robusta OX=6412 GN=20201522 PE=4 SV=1)

HSP 1 Score: 200.29 bits (508), Expect = 6.991e-58
Identity = 115/264 (43.56%), Postives = 159/264 (60.23%), Query Frame = 1 
Query:   97 ALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNYDLFKENFETKCTIELSKILDISSDHKFVQESVNLKNESDEE 888
             +FTPTNQKRLTNV+VV+L     K   RFEIACYPNKV +WR K+ET INEVLQ+ +V++NVSK ++A  + LK AF T +  +IC  IL KGELQ++EKER   IE+  +D+A +V  K +NP T   +P  +IE+ +KD H ++K NK++KQQ+L+ I+LL     I I  A   + + VP K  K V RE +    + I E   D DL +  + +PG +             E+S ++   S  K   E VNLK   D+E
Sbjct:    3 GIFTPTNQKRLTNVAVVRL----KKGGKRFEIACYPNKVTSWRSKVETDINEVLQTNMVFMNVSKGQMAKSDDLKAAFGTDDQKEICLQILSKGELQVSEKERSANIESSFRDIATVVADKCINPDTNRPYPVTLIERTLKDIHFSVKPNKNSKQQALEAIKLLMASGNIKIQRAQMRLKVHVPAKDGKKV-REKIRKLASKIEEDAFDDDLHMVFLVDPGAFR------------EVSNVVSTDSKGKGSVEVVNLKTVKDDE 249
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Cavefish
Match: sbds (SBDS ribosome maturation factor [Source:NCBI gene;Acc:103033486])

HSP 1 Score: 181.03 bits (458), Expect = 7.604e-54
Identity = 101/224 (45.09%), Postives = 147/224 (65.62%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY 765
            M++FTPTNQ RLTNV+VV++     K   RFEIACY NKV++WR   E  ++EVLQ+  V++NVSK ++A KE L ++F T ++ +ICK IL KGELQ+++KER  Q+E + +D+A IV  K +NP TK  +   +IE+ +KD H ++K NKS KQQ+LDVIR L  K  + I  A   +  T+P K+ K +K +L    + V SE   D  L++  + +PG +
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KKGGKRFEIACYKNKVMSWRAGAEKDLDEVLQTHTVFMNVSKGQVAKKEDLAKSFGTDDLTEICKQILAKGELQVSDKERQTQLEQMFRDIATIVAEKCVNPETKRPYTVNLIERAMKDIHYSVKANKSTKQQALDVIRQL--KESMQIQRAHMRLRFTLPAKEGKRLKDKLKPLLKVVESEDFDDQ-LEMVCLIDPGCF 217
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Yeast
Match: SDO1 (Guanine nucleotide exchange factor (GEF) for Ria1p; essential protein involved in ribosome maturation; with Ria1p, promotes release of Tif6p from 60S ribosomal subunits in the cytoplasm so that they can assemble with 40S subunits to generate mature ribosomes; ortholog of the human protein (SBDS) responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome; highly conserved across archaea and eukaryotes [Source:SGD;Acc:S000004012])

HSP 1 Score: 135.191 bits (339), Expect = 2.380e-37
Identity = 76/196 (38.78%), Postives = 125/196 (63.78%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITV--PQKQIKAVKR 675
            M +  P+ Q +LTNVS+V+L     K R RFE+ACY NKV  +R+ +E  ++EVLQ   V++NVSK  +A+KE L++ F T N+ D+ + I+ KGE+QL+EKER + +  +  ++  IV++K +NP +K  +P  +I K +++   +  +NK AK Q+L+ I+LL  K  IPI  A   V + +  P +Q + +++
Sbjct:    1 MPINQPSGQIKLTNVSLVRL----KKARKRFEVACYQNKVQDYRKGIEKDLDEVLQIHQVFMNVSKGLVANKEDLQKCFGTTNVDDVIEEIMHKGEIQLSEKERQLMLNKVNNEMLTIVSAKCINPVSKKRYPPTMIHKALQELKFSPVINKPAKLQALEAIKLLVSKQIIPIVRAKMKVKVAISEPSRQPELIEK 192
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Nematostella
Match: EDO44174 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWI6])

HSP 1 Score: 186.037 bits (471), Expect = 2.927e-56
Identity = 105/222 (47.30%), Postives = 142/222 (63.96%), Query Frame = 1 
Query:  100 LFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNY 765
            +FTPTNQ +LTNV+VV+L     K   RFEIACY NKV++WR  +E  I+EVLQ+  V+ NVSK ++A  E L  AF T N  DIC  IL KGELQ++EKER  Q+E+  +D+A IV  K +NP TK  +P GVIE+ +KD H ++   +S+KQQ+L+VIR L  K  + ID A   + + +P K  K V+ +L      V SE   D DL+I  + +PG Y
Sbjct:    4 IFTPTNQVKLTNVAVVRL----KKSGKRFEIACYKNKVMSWRTNVEKDIDEVLQTHTVFTNVSKGQVAKNEDLVRAFGTDNQTDICLKILAKGELQVSEKERNQQLESSFRDIATIVADKCVNPETKRPYPVGVIERAMKDIHYSVIPTRSSKQQALEVIRQL--KENMQIDRAQMRLRLVLPGKDAKKVQEKLRPLMTKVESEEW-DMDLEIVCLVDPGCY 218
[Close]
BLAST of ribosome maturation protein SBDS vs. Ensembl Medaka
Match: sbds (SBDS ribosome maturation factor [Source:NCBI gene;Acc:101161663])

HSP 1 Score: 176.792 bits (447), Expect = 2.826e-52
Identity = 94/196 (47.96%), Postives = 133/196 (67.86%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKREL 681
            M++FTPTNQ RLTNV+VV++     K   RFEIACY NKV++WR   E  ++EVLQ+  V++NVSK + A K+ L +AF T +  +ICK IL KGELQ+++KER  Q+ET+ +D+A  V  K +NP TK  +P  +IE+ +KD H ++K NKS KQQ+L+VIR LK   E  I  A   + + +P K+ K +K +L
Sbjct:    1 MSIFTPTNQIRLTNVAVVRM----KKGGKRFEIACYKNKVMSWRTGAEKDLDEVLQTPSVFINVSKGQTAKKDDLLKAFGTEDQTEICKQILAKGELQVSDKERQTQLETMFRDIATTVADKCVNPETKRPYPVSMIERAMKDIHYSVKPNKSTKQQALEVIRQLKETME--IQRAHMRLRLQLPAKEAKRLKEKL 190
[Close]
BLAST of ribosome maturation protein SBDS vs. Planmine SMEST
Match: SMESG000077964.1 (SMESG000077964.1)

HSP 1 Score: 631.713 bits (1628), Expect = 0.000e+0
Identity = 366/366 (100.00%), Postives = 366/366 (100.00%), Query Frame = 1 
Query:   94 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNYDLFKENFETKCTIELSKILDISSDHKFVQESVNLKNESDEEKEKGSENVSTSKTNKAXXXXXXXXXXXXXXXXVAKNSQRNKKNXXXXXXXXXXXXXXXXXXXXXXXXXXXRRRAKNKAVGDELHAEVAESKNELASSDEED 1191
            MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNYDLFKENFETKCTIELSKILDISSDHKFVQESVNLKNESDEEKEKGSENVSTSKTNKAEYDSDKEKCEEDETDKVAKNSQRNKKNKEYSSSVKDDSDEEKVEEKEKVMTKKSRRRAKNKAVGDELHAEVAESKNELASSDEED
Sbjct:    1 MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETKINEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLTEKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKLNKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYSENVISETLQDHDLKIEAVFEPGNYDLFKENFETKCTIELSKILDISSDHKFVQESVNLKNESDEEKEKGSENVSTSKTNKAEYDSDKEKCEEDETDKVAKNSQRNKKNKEYSSSVKDDSDEEKVEEKEKVMTKKSRRRAKNKAVGDELHAEVAESKNELASSDEED 366
The following BLAST results are available for this feature:
BLAST of ribosome maturation protein SBDS vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
SBDS1.773e-5040.23SBDS ribosome maturation factor [Source:HGNC Symbo... [more]
SBDS2.854e-5040.23SBDS ribosome maturation factor [Source:HGNC Symbo... [more]
SBDS3.041e-2354.32SBDS ribosome maturation factor [Source:HGNC Symbo... [more]
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BLAST of ribosome maturation protein SBDS vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
sbds-14.485e-5140.00Ribosome maturation protein SBDS [Source:UniProtK... [more]
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BLAST of ribosome maturation protein SBDS vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG85493.295e-4738.16gene:FBgn0035714 transcript:FBtr0076943[more]
CG85493.295e-4738.16gene:FBgn0035714 transcript:FBtr0330060[more]
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BLAST of ribosome maturation protein SBDS vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
sbds1.354e-5442.17SBDS ribosome maturation factor [Source:ZFIN;Acc:Z... [more]
sbds1.292e-5241.41SBDS ribosome maturation factor [Source:ZFIN;Acc:Z... [more]
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BLAST of ribosome maturation protein SBDS vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
sbds7.443e-5241.80SBDS ribosome assembly guanine nucleotide exchange... [more]
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BLAST of ribosome maturation protein SBDS vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Sbds3.089e-5041.02SBDS ribosome maturation factor [Source:MGI Symbol... [more]
Sbds8.689e-3048.39SBDS ribosome maturation factor [Source:MGI Symbol... [more]
Sbds5.848e-1159.09SBDS ribosome maturation factor [Source:MGI Symbol... [more]
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BLAST of ribosome maturation protein SBDS vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A5D8M6|SBDS_XENLA7.701e-5242.58Ribosome maturation protein SBDS OS=Xenopus laevis... [more]
sp|Q6DIT8|SBDS_XENTR3.943e-5141.80Ribosome maturation protein SBDS OS=Xenopus tropic... [more]
sp|Q23202|SBDS_CAEEL5.706e-5040.00Ribosome maturation protein SBDS OS=Caenorhabditis... [more]
sp|Q5RAZ2|SBDS_PONAB8.513e-5040.23Ribosome maturation protein SBDS OS=Pongo abelii O... [more]
sp|Q9Y3A5|SBDS_HUMAN8.513e-5040.23Ribosome maturation protein SBDS OS=Homo sapiens O... [more]
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BLAST of ribosome maturation protein SBDS vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Z2DM932.339e-5845.88Ribosome maturation protein OS=Schistosoma japonic... [more]
A0A183MN082.476e-5846.12Uncharacterized protein OS=Schistosoma margrebowie... [more]
Q5DG224.385e-5845.88SJCHGC02313 protein OS=Schistosoma japonicum OX=61... [more]
A0A4S2LMB44.928e-5842.64Uncharacterized protein OS=Opisthorchis felineus O... [more]
T1EY726.991e-5843.56Uncharacterized protein OS=Helobdella robusta OX=6... [more]
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BLAST of ribosome maturation protein SBDS vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
sbds7.604e-5445.09SBDS ribosome maturation factor [Source:NCBI gene;... [more]
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BLAST of ribosome maturation protein SBDS vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of ribosome maturation protein SBDS vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
SDO12.380e-3738.78Guanine nucleotide exchange factor (GEF) for Ria1p... [more]
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BLAST of ribosome maturation protein SBDS vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO441742.927e-5647.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ribosome maturation protein SBDS vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
sbds2.826e-5247.96SBDS ribosome maturation factor [Source:NCBI gene;... [more]
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BLAST of ribosome maturation protein SBDS vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000077964.10.000e+0100.00SMESG000077964.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034427 ID=SMED30034427|Name=ribosome maturation protein SBDS|organism=Schmidtea mediterranea sexual|type=transcript|length=1327bp
TAATTAGAGTTATATTCAGAATTAAGGCTTATATTAAGGTTAAATATCTC
ATTTAAACATTTTCTAATTATTCTTTATTTGGATAGTAGTTTTATGGCAC
TTTTCACACCGACTAACCAAAAACGATTAACAAATGTATCGGTTGTTAAG
TTAATAGTTAAGGTTGATAAAAAACGCCATCGCTTTGAGATTGCATGTTA
TCCAAACAAAGTTATAGCGTGGCGACAAAAACTAGAAACAAAAATTAATG
AGGTTCTACAATCCGAATTGGTTTATGTAAACGTTTCGAAAGCTGAAATT
GCTAGTAAAGAAAGTTTAAAAGAAGCTTTTCAGACAGCGAATATTTTAGA
TATTTGCAAAACAATTCTAGATAAAGGAGAATTACAGTTAACTGAAAAAG
AGCGTCTGGTTCAAATAGAAACTTTAACCAAAGACGTAGCAAAAATCGTT
ACTAGTAAAACTCTTAATCCTAGTACTAAAGTTTGCTTTCCATCTGGTGT
CATTGAAAAAATGATTAAAGATTGTCATATTAATTTAAAATTGAACAAGT
CTGCTAAACAACAATCATTAGACGTTATTCGTCTTCTGAAACGAAAATCG
GAAATACCAATTGATATGGCACTATTTTCGGTCATTATCACAGTTCCACA
AAAACAAATAAAAGCTGTTAAACGAGAACTGTTGAATTATAGTGAAAATG
TCATTAGCGAAACCCTCCAAGATCACGATTTAAAGATAGAAGCAGTATTT
GAACCGGGAAATTATGATTTATTTAAAGAAAACTTTGAGACAAAATGCAC
TATTGAGTTATCCAAAATTTTGGATATATCTTCCGATCATAAATTTGTAC
AAGAAAGTGTCAATTTAAAAAATGAATCTGATGAAGAAAAAGAAAAAGGC
AGTGAAAATGTTTCCACTAGTAAAACTAACAAGGCTGAATATGACTCTGA
TAAGGAAAAATGTGAAGAAGACGAAACCGATAAGGTAGCGAAGAATTCAC
AGAGGAATAAAAAAAATAAAGAATACAGTTCATCCGTGAAAGATGATTCA
GATGAAGAAAAGGTAGAAGAGAAAGAGAAAGTTATGACTAAAAAATCCAG
AAGACGAGCTAAAAACAAAGCGGTAGGAGATGAGTTACACGCGGAAGTTG
CAGAATCTAAAAATGAGCTCGCTTCTTCAGACGAAGAAGATAATGGTAAA
TCTCGTCGACGTGGAAAGAAACGAAACAACCGAAAATGAGTCCTCAAATG
TAGTTCTAAGTTTTGTTTCTATAATTAACAATTTCAAATTGTGTATCATT
GATAATAAATGCCATTTTCTTTAAAAA
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protein sequence of SMED30034427-orf-1

>SMED30034427-orf-1 ID=SMED30034427-orf-1|Name=SMED30034427-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=382bp
MALFTPTNQKRLTNVSVVKLIVKVDKKRHRFEIACYPNKVIAWRQKLETK
INEVLQSELVYVNVSKAEIASKESLKEAFQTANILDICKTILDKGELQLT
EKERLVQIETLTKDVAKIVTSKTLNPSTKVCFPSGVIEKMIKDCHINLKL
NKSAKQQSLDVIRLLKRKSEIPIDMALFSVIITVPQKQIKAVKRELLNYS
ENVISETLQDHDLKIEAVFEPGNYDLFKENFETKCTIELSKILDISSDHK
FVQESVNLKNESDEEKEKGSENVSTSKTNKAEYDSDKEKCEEDETDKVAK
NSQRNKKNKEYSSSVKDDSDEEKVEEKEKVMTKKSRRRAKNKAVGDELHA
EVAESKNELASSDEEDNGKSRRRGKKRNNRK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002032epidermal cell
PLANA:0002056medial muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR036786Ribosome_mat_SBDS_N_sf
IPR037188Sdo1/SBDS_central_sf
IPR002140Sdo1/SBDS
IPR039100Sdo1/SBDS-like
IPR018978Ribosome_mat_SBDS_C
IPR019783Ribosome_mat_SBDS_N
Vocabulary: biological process
TermDefinition
GO:0042254ribosome biogenesis
GO:0042256mature ribosome assembly
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR036786Ribosome maturation protein SBDS, N-terminal domain superfamilyGENE3DG3DSA:3.30.1250.10coord: 1..98
e-value: 1.3E-34
score: 120.1
IPR036786Ribosome maturation protein SBDS, N-terminal domain superfamilySUPERFAMILYSSF89895FYSH domaincoord: 21..98
IPR037188Ribosome maturation protein Sdo1/SBDS, central domain superfamilyGENE3DG3DSA:1.10.10.900coord: 102..176
e-value: 9.2E-22
score: 78.9
IPR037188Ribosome maturation protein Sdo1/SBDS, central domain superfamilySUPERFAMILYSSF109728Hypothetical protein AF0491, middle domaincoord: 93..166
IPR002140Ribosome maturation protein Sdo1/SBDSTIGRFAMTIGR00291TIGR00291coord: 20..238
e-value: 7.3E-40
score: 134.8
IPR019783Ribosome maturation protein SBDS, N-terminalPFAMPF01172SBDScoord: 21..104
e-value: 7.4E-26
score: 90.1
IPR018978Ribosome maturation protein SBDS, C-terminalPFAMPF09377SBDS_Ccoord: 112..229
e-value: 1.1E-22
score: 80.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 340..372
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 257..381
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 280..332
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 257..273
NoneNo IPR availablePANTHERPTHR10927:SF1RIBOSOME MATURATION PROTEIN SBDScoord: 2..246
IPR039100Ribosome maturation protein Sdo1/SBDS-likePANTHERPTHR10927RIBOSOME MATURATION PROTEIN SBDScoord: 2..246