SMED30034418

Overview


Name	SMED30034418
Smed ID	SMED30034418
Length (bp)	1623

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SMED30034418 (SMED30034418) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30034418 (SMED30034418) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30034418 (SMED30034418) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30034418 (SMED30034418) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034418

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
gut	SMED30034418	SMESG000015187.1	dd_Smed_v4_5922_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30034418	SMESG000015187.1	dd_Smed_v4_5922_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Alignments

SMED30034418 aligns in the following genomic locations:


Alignment Location	Alignment Score
v31.012448:17276..19026 -	7817
v31.007124:16245..17995 +	7691

Homology

[Close]

BLAST of SMED30034418 vs. Ensembl Human
Match: RAC1 (Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801])

HSP 1 Score: 185.652 bits (470), Expect = 2.759e-55
Identity = 91/194 (46.91%), Postives = 132/194 (68.04%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 192

[Close]

BLAST of SMED30034418 vs. Ensembl Human
Match: RAC2 (Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802])

HSP 1 Score: 182.185 bits (461), Expect = 7.843e-54
Identity = 87/186 (46.77%), Postives = 131/186 (70.43%), Query Frame = -2

Query:   93 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPE-TRKSK 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + + ++ V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S AS+ N+++KW+PEV+++ P+TP+++VGTKLDL  ++DKD +   K+ +            +++I ++ Y+ECSA  ++     F+ A++AVL P+ TR+ K
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDL--RDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQK 186

[Close]

BLAST of SMED30034418 vs. Ensembl Human
Match: RAC3 (Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803])

HSP 1 Score: 181.03 bits (458), Expect = 2.107e-53
Identity = 85/177 (48.02%), Postives = 124/177 (70.06%), Query Frame = -2

Query:  117 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ P+TP+++VGTKLDL  ++DKD +   +D +            +R+I ++ Y+ECSA  ++     F+ A++AVL
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDL--RDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVL 177

[Close]

BLAST of SMED30034418 vs. Ensembl Human
Match: RAC1 (Rac family small GTPase 1 [Source:HGNC Symbol;Acc:HGNC:9801])

HSP 1 Score: 174.096 bits (440), Expect = 1.403e-50
Identity = 91/213 (42.72%), Postives = 132/213 (61.97%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPD-------------------SDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP                    +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 211

[Close]

BLAST of SMED30034418 vs. Ensembl Human
Match: CDC42 (cell division cycle 42 [Source:HGNC Symbol;Acc:HGNC:1736])

HSP 1 Score: 172.94 bits (437), Expect = 1.907e-50
Identity = 84/185 (45.41%), Postives = 119/185 (64.32%), Query Frame = -2

Query:   87 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL---------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 614
            IK VV+GDG VGKTCLLI +  +K+   YVPT+FDN    + +G E   L L+DTAGQ+DYDRLRPLSYP +DVFL+CFS+ S +SF N++ KW PE+ ++ P TP ++VGT++DL         + KN +  +   +  E  +R +KA+ Y+ECSA  ++     F+ A+ A L P   + K K
Sbjct:    4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPIT-PETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEPPETQPKRK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Celegans
Match: mig-2 (Rac-like GTPase [Source:UniProtKB/TrEMBL;Acc:G5EBV3])

HSP 1 Score: 193.356 bits (490), Expect = 1.424e-58
Identity = 95/192 (49.48%), Postives = 132/192 (68.75%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVET---------FSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDGTVGKTC+LI +  D +   YVPT+FDN   +M L   VV+L LWDTAGQ+DYDRLRPLSYP +DVF+LCFS+ S  SF+N+ SKW PE++ + P+ PV++VGTKLDL  + +    AL  + ++          ++KIKA+ Y+ECSA  ++  +  FE AV+++LHP+ +K K   K C I+
Sbjct:    8 IKCVVVGDGTVGKTCMLISYTTDSFPVQYVPTVFDNYSAQMSLDGNVVNLGLWDTAGQEDYDRLRPLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKLDLRDEAEP-MRALQAEGKSPISKTQGMKMAQKIKAVKYLECSALTQQGLTQVFEDAVRSILHPKPQKKK---KSCNIM 195

[Close]

BLAST of SMED30034418 vs. Ensembl Celegans
Match: ced-10 (Ras-related protein ced-10 [Source:UniProtKB/Swiss-Prot;Acc:Q03206])

HSP 1 Score: 185.652 bits (470), Expect = 1.246e-55
Identity = 88/194 (45.36%), Postives = 128/194 (65.98%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +    ++L LWDTAGQ+DYDRLRPLSYP +DVFL+CF+L + ASF N+++KW+PEV ++ PNTP+++VGTK DL  + D+D +   ++              +++IKA+ Y+ECSA  ++     F+ A++AVL P  R  KSK   C +L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADL--REDRDTVERLRERRLQPVSQTQGYVMAKEIKAVKYLECSALTQRGLKQVFDEAIRAVLTPPQRAKKSK---CTVL 191

[Close]

BLAST of SMED30034418 vs. Ensembl Celegans
Match: cdc-42 (Cell division control protein 42 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q05062])

HSP 1 Score: 169.474 bits (428), Expect = 1.575e-49
Identity = 85/186 (45.70%), Postives = 121/186 (65.05%), Query Frame = -2

Query:   87 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL---------ITKNDKDYLALHKDV-ETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 614
            IK VV+GDG VGKTCLLI +  +K+   YVPT+FDN    + +G E   L L+DTAGQ+DYDRLRPLSYP +DVFL+CFS+ + ASF N++ KW PE+ ++   TP ++VGT++DL         + KN +    +  DV E  ++++KA+ Y+ECSA  +K     F+ A+ A L P  ++ K K
Sbjct:    4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVAPASFENVREKWVPEISHHCSKTPFLLVGTQVDLRDDPGMLEKLAKNKQK--PVSTDVGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALDPPQQEKKKK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Celegans
Match: rac-2 (Ras-related protein rac-2 [Source:UniProtKB/Swiss-Prot;Acc:Q94124])

HSP 1 Score: 167.548 bits (423), Expect = 9.074e-49
Identity = 80/195 (41.03%), Postives = 125/195 (64.10%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYL----------ALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLH-PETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLL+ +  + +   Y+ T+FD   T + +    ++L+LWDTAGQDDYD+ R LS+P +DVFL+CF+L + ASF N+++KW+PEV ++ PNTP+++VGTK DL  + D+D +            H      +++IKA+ Y+ECSA  +      F+ A++  L  P+T ++++K   C +L
Sbjct:    3 AIKCVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYSTNVMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADL--REDRDTIERLRERRLQPVSHTQGYVMAKEIKAVKYLECSALTQIGLKQVFDEAIRTGLTPPQTPQTRAKKSNCTVL 195

[Close]

BLAST of SMED30034418 vs. Ensembl Celegans
Match: rho-1 (Ras-like GTP-binding protein rhoA [Source:UniProtKB/Swiss-Prot;Acc:Q22038])

HSP 1 Score: 163.31 bits (412), Expect = 3.994e-47
Identity = 77/174 (44.25%), Postives = 115/174 (66.09%), Query Frame = -2

Query:  114 KIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLIT--KNDKDYLALHKDV------ETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLH 611
            K+V++GDG  GKTCLLI F+ D++ ++YVPT+F+N    +++  + V+L LWDTAGQ+DYDRLRPLSYPD+DV L+CFS++S  S  NI  KW PEV+++ PN P+++VG K DL +  +  ++   + ++          + +I A  Y+ECSA+ K      FE A +A L 
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPDVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRDLRSDPQTVRELAKMKQEPVKPEQGRAIAEQIGAFAYLECSAKTKDGIREVFEKATQAALQ 180

[Close]

BLAST of SMED30034418 vs. Ensembl Fly
Match: Mtl (gene:FBgn0039532 transcript:FBtr0085192)

HSP 1 Score: 187.963 bits (476), Expect = 2.371e-56
Identity = 90/193 (46.63%), Postives = 130/193 (67.36%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLA----------LHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDGTVGKTC+LI +  D +   YVPT+FDN    M++    V L LWDTAGQ+DYDRLRPLSYP +DVFL+C+S+ S +SF N+ SKW+PE++++ P+ P+++VGTK+DL  + D++ L+            +  +  + KI+A+ Y+ECSA  ++     FE AV+AVL PE  K + +   CLI+
Sbjct:    7 IKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDL--REDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRPEPLKRRQRK--CLIM 195

[Close]

BLAST of SMED30034418 vs. Ensembl Fly
Match: Mtl (gene:FBgn0039532 transcript:FBtr0085191)

HSP 1 Score: 187.963 bits (476), Expect = 2.371e-56
Identity = 90/193 (46.63%), Postives = 130/193 (67.36%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLA----------LHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDGTVGKTC+LI +  D +   YVPT+FDN    M++    V L LWDTAGQ+DYDRLRPLSYP +DVFL+C+S+ S +SF N+ SKW+PE++++ P+ P+++VGTK+DL  + D++ L+            +  +  + KI+A+ Y+ECSA  ++     FE AV+AVL PE  K + +   CLI+
Sbjct:    7 IKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDL--REDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRPEPLKRRQRK--CLIM 195

[Close]

BLAST of SMED30034418 vs. Ensembl Fly
Match: Mtl (gene:FBgn0039532 transcript:FBtr0085193)

HSP 1 Score: 187.963 bits (476), Expect = 2.371e-56
Identity = 90/193 (46.63%), Postives = 130/193 (67.36%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLA----------LHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDGTVGKTC+LI +  D +   YVPT+FDN    M++    V L LWDTAGQ+DYDRLRPLSYP +DVFL+C+S+ S +SF N+ SKW+PE++++ P+ P+++VGTK+DL  + D++ L+            +  +  + KI+A+ Y+ECSA  ++     FE AV+AVL PE  K + +   CLI+
Sbjct:    7 IKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDL--REDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRPEPLKRRQRK--CLIM 195

[Close]

BLAST of SMED30034418 vs. Ensembl Fly
Match: RhoL (gene:FBgn0014380 transcript:FBtr0082124)

HSP 1 Score: 182.57 bits (462), Expect = 2.416e-54
Identity = 82/183 (44.81%), Postives = 125/183 (68.31%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            +KI ++GDG VGKTC+LI +  +++ E Y+PT+FDN    + + +   +L LWDTAGQ+DY+RLRPLSYP ++ FLLC+S+ SR SF N++SKWWPE++++  + PVV+VGTKLDL   N + ++   +  +   ++I A + +ECSA+ K+N    FE AV+AV   E +   +  + C IL
Sbjct:   12 LKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLRPLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTKLDLRIPNSEKFVTTQEG-KKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAV---ERKPKTTSKQSCKIL 190

[Close]

BLAST of SMED30034418 vs. Ensembl Fly
Match: RhoL (gene:FBgn0014380 transcript:FBtr0305340)

HSP 1 Score: 181.8 bits (460), Expect = 7.927e-54
Identity = 82/183 (44.81%), Postives = 126/183 (68.85%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            +KI ++GDG VGKTC+LI +  +++ E Y+PT+FDN    + + +   +L LWDTAGQ+DY+RLRPLSYP ++ FLLC+S+ SR SF N++SKWWPE++++  + PVV+VGTKLDL   N + ++   ++ +   ++I A + +ECSA+ K+N    FE AV+AV   E +   +  + C IL
Sbjct:   36 LKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLRPLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTKLDLRIPNSEKFVTT-QEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAV---ERKPKTTSKQSCKIL 214

[Close]

BLAST of SMED30034418 vs. Ensembl Zebrafish
Match: rac3b (Rac family small GTPase 3b [Source:ZFIN;Acc:ZDB-GENE-080220-21])

HSP 1 Score: 188.734 bits (478), Expect = 1.193e-56
Identity = 90/187 (48.13%), Postives = 128/187 (68.45%), Query Frame = -2

Query:   87 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   +D +            +R+I A+ Y+ECSA  ++     F+ A++AVL P   K + K
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIERLRDKKLSPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Zebrafish
Match: rac3a (Rac family small GTPase 3a [Source:ZFIN;Acc:ZDB-GENE-040718-256])

HSP 1 Score: 188.734 bits (478), Expect = 1.258e-56
Identity = 90/187 (48.13%), Postives = 128/187 (68.45%), Query Frame = -2

Query:   87 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   +D +            +R+I A+ Y+ECSA  ++     F+ A++AVL P   K + K
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIERLRDKKLAPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Zebrafish
Match: rac2 (Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GENE-040625-27])

HSP 1 Score: 184.111 bits (466), Expect = 7.587e-55
Identity = 89/194 (45.88%), Postives = 135/194 (69.59%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + + ++ V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ P+TP+++VGTKLDL  +++K+ +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P+   +K K K C++L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPSTPIILVGTKLDL--RDEKETIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQ--PTKVKKKGCVML 192

[Close]

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + + ++ V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ P+TP+++VGTKLDL  +++K+ +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P+   +K K K C++L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPSTPIILVGTKLDL--RDEKETIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQ--PTKVKKKGCVML 192

[Close]

BLAST of SMED30034418 vs. Ensembl Zebrafish
Match: rac1a (Rac family small GTPase 1a [Source:ZFIN;Acc:ZDB-GENE-030131-5415])

HSP 1 Score: 184.111 bits (466), Expect = 8.254e-55
Identity = 91/194 (46.91%), Postives = 132/194 (68.04%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K +   + CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKRRR--RRCLLL 192

[Close]

BLAST of SMED30034418 vs. Ensembl Xenopus
Match: nab2 (NGFI-A binding protein 2 (EGR1 binding protein 2) [Source:Xenbase;Acc:XB-GENE-957953])

HSP 1 Score: 186.422 bits (472), Expect = 1.401e-55
Identity = 89/187 (47.59%), Postives = 126/187 (67.38%), Query Frame = -2

Query:   87 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   +D              +R+I ++ Y+ECSA  ++     F+ A++AVL P   K   K
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIERLRDKRLSPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKRAGK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Xenopus
Match: rac1 (Rac family small GTPase 1 [Source:NCBI gene;Acc:448118])

HSP 1 Score: 185.652 bits (470), Expect = 2.501e-55
Identity = 91/194 (46.91%), Postives = 132/194 (68.04%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 192

[Close]

BLAST of SMED30034418 vs. Ensembl Xenopus
Match: rhogl.1 (ras homolog family member G like gene 1 [Source:NCBI gene;Acc:100216282])

HSP 1 Score: 185.267 bits (469), Expect = 3.772e-55
Identity = 87/193 (45.08%), Postives = 130/193 (67.36%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYL----------ALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDG VGKTCLLI +  + + E Y+PT+FDN   +M +    V LNLWDTAGQ++YDRLR LSYP ++VF++CFS+ S +S+ N++ KW PEV ++ PN P+++VGTK DL  +ND + +            ++   + +++I A+ Y+ECSA  ++     FE AV+AVL+P T+K+   PK C++L
Sbjct:    4 IKCVVVGDGAVGKTCLLISYTTNAFPEEYIPTVFDNYSAQMTVDGRTVSLNLWDTAGQEEYDRLRTLSYPQTNVFIICFSIGSPSSYANVRHKWHPEVSHHCPNVPILLVGTKQDL--RNDSETIKKLKEQSLAPTTNQQGSSLAKQIGAVKYMECSALHQQGVRQVFEEAVRAVLYPVTKKN---PKKCVLL 191

[Close]

BLAST of SMED30034418 vs. Ensembl Xenopus
Match: yju2 (YJU2 splicing factor homolog [Source:Xenbase;Acc:XB-GENE-5938025])

HSP 1 Score: 182.57 bits (462), Expect = 3.903e-54
Identity = 89/195 (45.64%), Postives = 137/195 (70.26%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVL-HPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + + ++ V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S AS+ N+++KW+PEV+++ P+TP+++VGTKLDL  ++DK+ +   K+ +            +++I+A+ Y+ECSA  ++     F+ A++AVL  P +R +K+K   C++L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDL--RDDKETIEKLKEKKLSPISYPQGLALAKEIEAVKYLECSALTQRGLKTVFDEAIRAVLCPPPSRPNKAK---CVVL 192

[Close]

BLAST of SMED30034418 vs. Ensembl Xenopus
Match: nab2 (NGFI-A binding protein 2 (EGR1 binding protein 2) [Source:Xenbase;Acc:XB-GENE-957953])

HSP 1 Score: 176.792 bits (447), Expect = 6.783e-52
Identity = 85/186 (45.70%), Postives = 124/186 (66.67%), Query Frame = -2

Query:   87 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 614
            ++ V+I  G VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   +D              +R+I ++ Y+ECSA  ++     F+ A++AVL P   K   K
Sbjct:    4 LRCVIICWGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIERLRDKRLSPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKRAGK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Mouse
Match: Rac1 (Rac family small GTPase 1 [Source:MGI Symbol;Acc:MGI:97845])

HSP 1 Score: 185.652 bits (470), Expect = 1.894e-55
Identity = 91/194 (46.91%), Postives = 132/194 (68.04%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 192

[Close]

BLAST of SMED30034418 vs. Ensembl Mouse
Match: Rac2 (Rac family small GTPase 2 [Source:MGI Symbol;Acc:MGI:97846])

HSP 1 Score: 182.956 bits (463), Expect = 2.446e-54
Identity = 85/188 (45.21%), Postives = 130/188 (69.15%), Query Frame = -2

Query:   84 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKP 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + + ++ V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S AS+ N+++KW+PEV+++ P+TP+++VGTKLDL  ++DKD +   K+ +            ++ I ++ Y+ECSA  ++     F+ A++AVL P+  + + +P
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDL--RDDKDTIEKLKEKKLAPITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRP 188

[Close]

BLAST of SMED30034418 vs. Ensembl Mouse
Match: Rac3 (Rac family small GTPase 3 [Source:MGI Symbol;Acc:MGI:2180784])

HSP 1 Score: 181.03 bits (458), Expect = 1.447e-53
Identity = 85/177 (48.02%), Postives = 124/177 (70.06%), Query Frame = -2

Query:  117 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ P+TP+++VGTKLDL  ++DKD +   +D +            +R+I ++ Y+ECSA  ++     F+ A++AVL
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDL--RDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVL 177

[Close]

BLAST of SMED30034418 vs. Ensembl Mouse
Match: Cdc42 (cell division cycle 42 [Source:MGI Symbol;Acc:MGI:106211])

HSP 1 Score: 172.94 bits (437), Expect = 1.309e-50
Identity = 84/185 (45.41%), Postives = 119/185 (64.32%), Query Frame = -2

Query:   87 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL---------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 614
            IK VV+GDG VGKTCLLI +  +K+   YVPT+FDN    + +G E   L L+DTAGQ+DYDRLRPLSYP +DVFL+CFS+ S +SF N++ KW PE+ ++ P TP ++VGT++DL         + KN +  +   +  E  +R +KA+ Y+ECSA  ++     F+ A+ A L P   + K K
Sbjct:    4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPIT-PETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEPPETQPKRK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Mouse
Match: Rac1 (Rac family small GTPase 1 [Source:MGI Symbol;Acc:MGI:97845])

HSP 1 Score: 173.711 bits (439), Expect = 1.361e-50
Identity = 91/213 (42.72%), Postives = 132/213 (61.97%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPD-------------------SDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP                    +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGDTCGKDRPSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 211

[Close]

BLAST of SMED30034418 vs. UniProt/SwissProt
Match: sp|Q6RUV5|RAC1_RAT (Ras-related C3 botulinum toxin substrate 1 OS=Rattus norvegicus OX=10116 GN=Rac1 PE=1 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 1.325e-54
Identity = 91/194 (46.91%), Postives = 132/194 (68.04%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 192

[Close]

BLAST of SMED30034418 vs. UniProt/SwissProt
Match: sp|P63001|RAC1_MOUSE (Ras-related C3 botulinum toxin substrate 1 OS=Mus musculus OX=10090 GN=Rac1 PE=1 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 1.325e-54
Identity = 91/194 (46.91%), Postives = 132/194 (68.04%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 192

[Close]

BLAST of SMED30034418 vs. UniProt/SwissProt
Match: sp|P63000|RAC1_HUMAN (Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 1.325e-54
Identity = 91/194 (46.91%), Postives = 132/194 (68.04%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 192

[Close]

BLAST of SMED30034418 vs. UniProt/SwissProt
Match: sp|P62999|RAC1_CANLF (Ras-related C3 botulinum toxin substrate 1 OS=Canis lupus familiaris OX=9615 GN=RAC1 PE=2 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 1.325e-54
Identity = 91/194 (46.91%), Postives = 132/194 (68.04%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 192

[Close]

BLAST of SMED30034418 vs. UniProt/SwissProt
Match: sp|P62998|RAC1_BOVIN (Ras-related C3 botulinum toxin substrate 1 OS=Bos taurus OX=9913 GN=RAC1 PE=1 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 1.325e-54
Identity = 91/194 (46.91%), Postives = 132/194 (68.04%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   K + +   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRK--CLLL 192

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BLAST of SMED30034418 vs. TrEMBL
Match: B4NIG4 (Uncharacterized protein OS=Drosophila willistoni OX=7260 GN=Dwil\GK14302 PE=4 SV=1)

HSP 1 Score: 197.593 bits (501), Expect = 1.070e-56
Identity = 90/183 (49.18%), Postives = 129/183 (70.49%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            +KI ++GDG VGKTC+LI +  +++ E YVPT+FDN    +++ +   +L LWDTAGQ+DY+RLRPLSYP+++ FLLC+S+ SR SF NI+SKWWPE+++Y  N PVV+VGTKLDL     + ++ L +      ++I A   +ECSA+ K+N SL FE AV+A      +K KSKP+ C +L
Sbjct:   12 LKITIVGDGMVGKTCMLITYTQNEFPEEYVPTVFDNHACNIQVDDHEYNLTLWDTAGQEDYERLRPLSYPNTNCFLLCYSISSRTSFENIKSKWWPEIRHYSNNVPVVLVGTKLDLRIPQSEKFVTLQEG-RRLRKEIHAYSLVECSAKKKQNLSLVFEEAVRAA----EKKPKSKPQTCTLL 189

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BLAST of SMED30034418 vs. TrEMBL
Match: G5EBV3 (Rac-like GTPase OS=Caenorhabditis elegans OX=6239 GN=mig-2 PE=1 SV=1)

HSP 1 Score: 193.356 bits (490), Expect = 5.369e-55
Identity = 95/192 (49.48%), Postives = 132/192 (68.75%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVET---------FSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDGTVGKTC+LI +  D +   YVPT+FDN   +M L   VV+L LWDTAGQ+DYDRLRPLSYP +DVF+LCFS+ S  SF+N+ SKW PE++ + P+ PV++VGTKLDL  + +    AL  + ++          ++KIKA+ Y+ECSA  ++  +  FE AV+++LHP+ +K K   K C I+
Sbjct:    8 IKCVVVGDGTVGKTCMLISYTTDSFPVQYVPTVFDNYSAQMSLDGNVVNLGLWDTAGQEDYDRLRPLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKLDLRDEAEP-MRALQAEGKSPISKTQGMKMAQKIKAVKYLECSALTQQGLTQVFEDAVRSILHPKPQKKK---KSCNIM 195

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BLAST of SMED30034418 vs. TrEMBL
Match: A0A4T0FV37 (Uncharacterized protein OS=Wallemia hederae OX=1540922 GN=E3P99_01020 PE=4 SV=1)

HSP 1 Score: 193.356 bits (490), Expect = 7.218e-55
Identity = 93/192 (48.44%), Postives = 129/192 (67.19%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL---------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDG VGKTCLLI +  +++   YVPT+FDN    + L  + V L LWDTAGQ+DYDRLRPLSYP +D+FL CFS+ S ASF N++ KWWPE+ ++ P  P+++VGTKLDL         +     + ++  + VE  S++I AI Y+ECSA  +K     F+ A++AVL P+ RKSK K K C+++
Sbjct:    6 IKCVVVGDGAVGKTCLLISYTTNQFPSDYVPTVFDNYQATVLLDGKPVLLGLWDTAGQEDYDRLRPLSYPQTDIFLCCFSIHSPASFENVKYKWWPEISHHAPGVPIILVGTKLDLRSDPQAVNALRARRMEPISYSQGVE-LSKEINAIKYLECSALTQKGLKGVFDEAIRAVLVPQGRKSKRKQKGCVLI 196

[Close]

BLAST of SMED30034418 vs. TrEMBL
Match: A8XQS8 (Protein CBR-MIG-2 OS=Caenorhabditis briggsae OX=6238 GN=mig-2 PE=4 SV=1)

HSP 1 Score: 192.971 bits (489), Expect = 7.690e-55
Identity = 93/192 (48.44%), Postives = 132/192 (68.75%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL---------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDGTVGKTC+LI +  D +   YVPT+FDN   +M L   +V+L LWDTAGQ+DYDRLRPLSYP +DVF+LCFS+ S  SF+N+ SKW PE++ + P+ PV++VGTKLDL         +    K  ++  + ++  ++KIKAI Y+ECSA  ++  +  FE AV+++LHP+ +K K   K C ++
Sbjct:    8 IKCVVVGDGTVGKTCMLISYTTDSFPVQYVPTVFDNYSAQMNLDGSIVNLGLWDTAGQEDYDRLRPLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKLDLRDEPEPMRVLQAEGKSPISKAQGLK-MAQKIKAIKYLECSALTQQGLTQVFEDAVRSILHPKPQKKK---KSCTLM 195

[Close]

BLAST of SMED30034418 vs. TrEMBL
Match: A0A2G5SP08 (Uncharacterized protein OS=Caenorhabditis nigoni OX=1611254 GN=Cnig_chr_X.g23152 PE=4 SV=1)

HSP 1 Score: 192.971 bits (489), Expect = 7.690e-55
Identity = 93/192 (48.44%), Postives = 132/192 (68.75%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL---------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDGTVGKTC+LI +  D +   YVPT+FDN   +M L   +V+L LWDTAGQ+DYDRLRPLSYP +DVF+LCFS+ S  SF+N+ SKW PE++ + P+ PV++VGTKLDL         +    K  ++  + ++  ++KIKAI Y+ECSA  ++  +  FE AV+++LHP+ +K K   K C ++
Sbjct:    8 IKCVVVGDGTVGKTCMLISYTTDSFPVQYVPTVFDNYSAQMNLDGSIVNLGLWDTAGQEDYDRLRPLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKLDLRDEPEPMRVLQAEGKSPISKAQGLK-MAQKIKAIKYLECSALTQQGLTQVFEDAVRSILHPKPQKKK---KSCTLM 195

[Close]

BLAST of SMED30034418 vs. Ensembl Cavefish
Match: rac3b (ras-related C3 botulinum toxin substrate 3-like [Source:NCBI gene;Acc:111192386])

HSP 1 Score: 188.734 bits (478), Expect = 1.011e-56
Identity = 90/187 (48.13%), Postives = 128/187 (68.45%), Query Frame = -2

Query:   87 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   +D +            +R+I A+ Y+ECSA  ++     F+ A++AVL P   K + K
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIERLRDKKLSPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Cavefish
Match: rac3a (Rac family small GTPase 3 [Source:NCBI gene;Acc:103047109])

HSP 1 Score: 188.734 bits (478), Expect = 1.066e-56
Identity = 90/187 (48.13%), Postives = 128/187 (68.45%), Query Frame = -2

Query:   87 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   +D +            +R+I A+ Y+ECSA  ++     F+ A++AVL P   K + K
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTIERLRDKKLAPITYPQGLAMAREIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRGK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975])

HSP 1 Score: 186.037 bits (471), Expect = 1.073e-55
Identity = 88/187 (47.06%), Postives = 129/187 (68.98%), Query Frame = -2

Query:   87 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++D+D +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   KS+ +
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDQDTIEKLKERKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKSRKR 187

[Close]

BLAST of SMED30034418 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975])

HSP 1 Score: 186.037 bits (471), Expect = 1.084e-55
Identity = 88/187 (47.06%), Postives = 130/187 (69.52%), Query Frame = -2

Query:   87 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++D+D +   K+ +            +++I A+ Y+ECSA  +++    F+ A++AVL P   KS+ +
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDQDTIEKLKERKLTPITYPQGLAMAKEIGAVKYLECSALTQRDLKTVFDEAIRAVLCPPPVKSRKR 187

[Close]

BLAST of SMED30034418 vs. Ensembl Cavefish
Match: rac1b (ras-related C3 botulinum toxin substrate 1-like [Source:NCBI gene;Acc:111192975])

HSP 1 Score: 186.037 bits (471), Expect = 1.084e-55
Identity = 88/187 (47.06%), Postives = 130/187 (69.52%), Query Frame = -2

Query:   87 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++D+D +   K+ +            +++I A+ Y+ECSA  +++    F+ A++AVL P   KS+ +
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDQDTIEKLKERKLTPITYPQGLAMAKEIGAVKYLECSALTQRDLKTVFDEAIRAVLCPPPVKSRKR 187

[Close]

BLAST of SMED30034418 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009835.1 (pep scaffold:Pmarinus_7.0:GL479385:19931:31465:1 gene:ENSPMAG00000008880.1 transcript:ENSPMAT00000009835.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 181.03 bits (458), Expect = 2.141e-54
Identity = 85/177 (48.02%), Postives = 124/177 (70.06%), Query Frame = -2

Query:  117 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DKD +   ++ +            +++I A+ Y+ECSA  ++     F+ A++AVL
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKDTVEKLREKKLAPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 177

[Close]

BLAST of SMED30034418 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007368.1 (pep scaffold:Pmarinus_7.0:GL476419:214196:224439:-1 gene:ENSPMAG00000006646.1 transcript:ENSPMAT00000007368.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 173.326 bits (438), Expect = 1.877e-51
Identity = 84/194 (43.30%), Postives = 129/194 (66.49%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTC+LI F+++ +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +D+FL+CFS+ S +S++N++ KW+ EV+++ P TP+++VGTK D   + DKD L   ++            + +++I AI Y+ECSA  ++     F+  V+AV+ PE +  + K K C +L
Sbjct:    3 AIKCVVVGDGAVGKTCMLISFSNNTFPGEYIPTVFDNYAVNLMVDGKYVNLGLWDTAGQEDYDRLRPLSYPQTDIFLICFSVVSPSSYDNVRVKWFKEVRHHCPETPIILVGTKQD--QREDKDILKHLEEKSMQPVTNAQGLSLAKEIGAIKYLECSALTQRGLKNVFDETVRAVISPEPKIERKK-KSCALL 193

[Close]

BLAST of SMED30034418 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002754.1 (pep scaffold:Pmarinus_7.0:GL476453:253767:255265:1 gene:ENSPMAG00000002511.1 transcript:ENSPMAT00000002754.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 172.94 bits (437), Expect = 2.381e-51
Identity = 85/190 (44.74%), Postives = 122/190 (64.21%), Query Frame = -2

Query:   72 KIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLA----------LHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCL 611
            K+VV+GDG  GKTCLL+ F+ DK+ ++YVPT+F+     +++    V+L LWDTAGQ+DYDRLRPLSYPD+DV L+CFS++S  S  N+  KW PEVQ++ PN P+V+V  K DL  + D+  L             +D  T + +I+A DY+ECSA+ K    L FE A +A +    ++SK + + C 
Sbjct:    9 KLVVVGDGACGKTCLLMVFSKDKFPDVYVPTVFETYVADIEVDGRQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENVPEKWVPEVQHFCPNVPIVLVANKKDL--RGDESVLQELARIKREPLKPEDGRTMASRIQAFDYVECSAQTKDGVRLVFETATRAAIQ---KQSKRRGRSCF 193

[Close]

BLAST of SMED30034418 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004439.1 (pep scaffold:Pmarinus_7.0:GL476335:1598569:1600956:1 gene:ENSPMAG00000004041.1 transcript:ENSPMAT00000004439.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 170.244 bits (430), Expect = 2.674e-50
Identity = 85/179 (47.49%), Postives = 116/179 (64.80%), Query Frame = -2

Query:   99 KIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLIT-KNDKDYLALHK-------DVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRK 611
            K+V++GDG  GKTCLLI F+ D++ E+YVPT+F+N    +++  + V+L LWDTAGQ+DYDRLRPLSYPD+DV L+CFS++S  S  NI  KW PEV+++ PN P+++VG K DL    N K  LA  K       +    + +I A  Y+ECSA+ K      FE A +A L    RK
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDDNTKRELAKMKQEPVRVEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAALQVRKRK 185

[Close]

BLAST of SMED30034418 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001838.1 (pep scaffold:Pmarinus_7.0:GL478831:173097:182385:-1 gene:ENSPMAG00000001664.1 transcript:ENSPMAT00000001838.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 167.162 bits (422), Expect = 4.848e-49
Identity = 83/176 (47.16%), Postives = 116/176 (65.91%), Query Frame = -2

Query:  114 KIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKND---KDYLALHK-------DVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLH 611
            K+V++GDG  GKTCLLI F+ D++ E+YVPT+F+N    +++  + V+L LWDTAGQ+DYDRLRPLSYPD+DV L+CFS++S  S  NI  KW PEV+++ PN P+++VG K DL  +ND   +  LA  K       +    + +I A  Y+ECSA+ K      FE A +A L 
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDL--RNDESTRRELAKMKQEPVKSEEGRDMANRINAFGYMECSAKTKDGVREVFEMATRAALQ 180

[Close]

BLAST of SMED30034418 vs. Ensembl Yeast
Match: CDC42 (Small rho-like GTPase; essential for establishment and maintenance of cell polarity; plays a role late in cell fusion via activation of key cell fusion regulator Fus2p; mutants have defects in the organization of actin and septins; human homolog CDC42 can complement yeast cdc42 mutant [Source:SGD;Acc:S000004219])

HSP 1 Score: 168.703 bits (426), Expect = 6.652e-50
Identity = 86/191 (45.03%), Postives = 121/191 (63.35%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL------ITKNDKDYLA--LHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            +K VV+GDG VGKTCLLI +  +++   YVPT+FDN    + +G+E   L L+DTAGQ+DYDRLRPLSYP +DVFL+CFS+ S  SF N++ KW+PEV ++ P  P ++VGT++DL      I K  +  L     +     +R++KA+ Y+ECSA  ++     F+ A+ A L P   K   K K C IL
Sbjct:    4 LKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPPVIK---KSKKCAIL 191

[Close]

BLAST of SMED30034418 vs. Ensembl Yeast
Match: RHO4 (Non-essential small GTPase; member of the Rho/Rac subfamily of Ras-like proteins; likely to be involved in the establishment of cell polarity; has long N-terminal extension that plays an important role in Rho4p function and is shared with Rho4 homologs in other yeasts and filamentous fungi [Source:SGD;Acc:S000001763])

HSP 1 Score: 158.688 bits (400), Expect = 5.965e-45
Identity = 72/167 (43.11%), Postives = 115/167 (68.86%), Query Frame = -2

Query:  117 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGN-EVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVL 614
            +KIVV+GDG VGKTCLLI +    +   Y+PTIF+N  T ++  N ++++L LWDTAGQ++Y RLRPLSY ++DV ++C+S+ S+ S  N++  W+PEV+++ P+TP+++VG K DL   ++   L      E+ ++++ A  +I+CSAR K+N    FE A+  +L
Sbjct:   73 LKIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLYEADNLSDLVEPSSAESLAKRLGAFAHIQCSARLKENIDEVFETAIHTLL 239

[Close]

BLAST of SMED30034418 vs. Ensembl Yeast
Match: RHO1 (GTP-binding protein of the rho subfamily of Ras-like proteins; involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p) [Source:SGD;Acc:S000006369])

HSP 1 Score: 153.68 bits (387), Expect = 3.671e-44
Identity = 75/180 (41.67%), Postives = 113/180 (62.78%), Query Frame = -2

Query:  102 KIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYL----------ALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETR 611
            K+V++GDG  GKTCLLI F+  ++ E+YVPT+F+N    +++    V+L LWDTAGQ+DYDRLRPLSYPDS+V L+CFS++   S  N+Q KW  EV ++    P+++VG K+DL  +ND   +             ++ ++ + +I A  Y ECSA+        FEAA +A L  +++
Sbjct:   12 KLVIVGDGACGKTCLLIVFSKGQFPEVYVPTVFENYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICFSIDLPDSLENVQEKWIAEVLHFCQGVPIILVGCKVDL--RNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYECSAKTGYGVREVFEAATRASLMGKSK 189

[Close]

BLAST of SMED30034418 vs. Ensembl Yeast
Match: RHO5 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; RAC1 ortholog; regulated by phosphorylation and ubiquitination; likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity [Source:SGD;Acc:S000005124])

HSP 1 Score: 133.65 bits (335), Expect = 2.093e-35
Identity = 80/226 (35.40%), Postives = 119/226 (52.65%), Query Frame = -2

Query:   90 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDN-------------KPTKMKLGNE-----------------VVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQ---NYKPNT--------PVVIVGTKLDL---------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVK-AVLHPETRKSKS 614
            IK V+IGDG VGKT LLI +  + +   YVPT+FDN              P ++  GN+                 +  +NLWDTAGQ+DYDRLRPL YP +D+FL+CFS+   ASF N+  KW PE++   N +  +        P+++VGTK DL         + + + DY++  ++++   ++   + Y ECSA  +      FE AV+ A+  PE+   KS
Sbjct:    4 IKCVIIGDGAVGKTSLLISYTTNSFPTDYVPTVFDNYSTTIAIPNGTASSPLELDNGNDKRGSLSSASSSPSTDRKLYKINLWDTAGQEDYDRLRPLCYPQTDIFLICFSVSEHASFANVTEKWLPELKQTSNIEGTSLYTKLGKYPILLVGTKSDLRDDPATQKKLQEANSDYVS-QEEIDELVQRCGFMGYTECSAATQAGVREVFEQAVRYAIYEPESPNQKS 228

[Close]

BLAST of SMED30034418 vs. Ensembl Yeast
Match: RHO2 (Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity and in microtubule assembly [Source:SGD;Acc:S000005034])

HSP 1 Score: 129.028 bits (323), Expect = 3.177e-35
Identity = 72/187 (38.50%), Postives = 104/187 (55.61%), Query Frame = -2

Query:   66 KIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL-----ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 611
            K+V+IGDG  GKT LL  F   K+ E Y PT+F+N  T  ++    V L LWDTAGQ++Y+RLRP SY  +D+ L+ F++++  S  N ++KW  E   Y P+ P+V+VG K DL       +N  D +   +D +  +R I A  Y+ECSA   +     FE A +  L     K +     C+IL
Sbjct:    9 KLVIIGDGACGKTSLLYVFTLGKFPEQYHPTVFENYVTDCRVDGIKVSLTLWDTAGQEEYERLRPFSYSKADIILIGFAVDNFESLINARTKWADEALRYCPDAPIVLVGLKKDLRQEAHFKENATDEMVPIEDAKQVARAIGAKKYMECSALTGEGVDDVFEVATRTSL---LMKKEPGANCCIIL 192

[Close]

BLAST of SMED30034418 vs. Ensembl Nematostella
Match: EDO38536 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCK6])

HSP 1 Score: 184.111 bits (466), Expect = 2.298e-55
Identity = 90/194 (46.39%), Postives = 130/194 (67.01%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + ++L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S AS+ N+++KW+PEV ++ PNTP+V+VGTKLDL  ++DK+ +   K+ +            +++I A+ Y+ECSA  +K     F+ A++AVL P     K + K C +L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLISPASYENVRAKWYPEVSHHCPNTPIVLVGTKLDL--RDDKETIDKLKEKKLGPIGYTQGLQMAKEIGAVKYLECSALTQKGLKTVFDEAIRAVLCPTKPAKKPRNKGCKLL 194

[Close]

BLAST of SMED30034418 vs. Ensembl Nematostella
Match: EDO37472 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFJ1])

HSP 1 Score: 176.792 bits (447), Expect = 1.537e-52
Identity = 85/185 (45.95%), Postives = 122/185 (65.95%), Query Frame = -2

Query:   87 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL---------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSK 614
            IK VV+GDG VGKTCLLI +  +K+   YVPT+FDN    + +G E   L L+DTAGQ+DYDRLRPLSYP +DVFL+CFS+ S +SF N++ KW PE+ ++ P TP ++VGT++DL         ++KN +  +A+    E  +R+++A+ Y+ECSA  +K     F+ A+ A L P   + K K
Sbjct:    4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQVDLRDDQGTIEKLSKNKQKPIAVEA-AEKLARELRAVKYVECSALTQKGLKNVFDEAILAALEPPEPQKKKK 187

[Close]

BLAST of SMED30034418 vs. Ensembl Nematostella
Match: EDO35019 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMN7])

HSP 1 Score: 173.711 bits (439), Expect = 1.861e-51
Identity = 82/178 (46.07%), Postives = 119/178 (66.85%), Query Frame = -2

Query:  114 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLH 617
             IK VV+GDG VGKTC+LI +  + +   Y+PT+FDN    + +    ++L LWDTAGQ+DYDRLRPLSYP +DVFL+CFS+ S ASF N+++KW+PEV ++ P TP+++VGTK DL  + DK+ +   K+ +            +++IKA  Y+ECSA  +K     F+ A++AVL 
Sbjct:    3 AIKCVVVGDGAVGKTCMLISYTTNAFPGEYIPTVFDNYSANVMVDGRPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSVISPASFENVRAKWYPEVSHHCPGTPIILVGTKTDL--REDKEMIEKLKEKKLNPLSTSHGLQMAKEIKAAKYLECSALTQKGLKTVFDDAIRAVLE 178

[Close]

BLAST of SMED30034418 vs. Ensembl Nematostella
Match: EDO39465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Y5])

HSP 1 Score: 168.703 bits (426), Expect = 1.652e-49
Identity = 83/174 (47.70%), Postives = 115/174 (66.09%), Query Frame = -2

Query:  114 KIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL-ITKNDKDYLALHK-------DVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLH 611
            K+V++GDG  GKTCLLI F+ D++ E+YVPT+F+N    +++  + V+L LWDTAGQ+DYDRLRPLSYPD+DV L+CFS++S  S  NI  KW PEV+++ PN P+++VG K DL + +N K  L   K       +    + KI A  Y+ECSA+ K      FE A +A L 
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRMDENTKRELQKMKQEPVKIEEGRAMADKISAYAYLECSAKTKDGVREVFETATRAALQ 180

[Close]

BLAST of SMED30034418 vs. Ensembl Nematostella
Match: EDO40156 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7Y6])

HSP 1 Score: 134.035 bits (336), Expect = 2.184e-36
Identity = 66/183 (36.07%), Postives = 108/183 (59.02%), Query Frame = -2

Query:   96 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL---------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPF-EAAVKAVLHPETRKS 614
            +K V++GDG VGKT LL+ +  D +   YVPT FD     +++  ++  +   DTAGQ+D+D LRPL Y  +DVF++CFS+ S  SF N+ SKW PE++ ++P  P+++VGT  DL         +++ D   +++ K  E   +K + + Y+E S+  +KN    F EA +   L P+  ++
Sbjct:   19 LKCVIVGDGGVGKTSLLVSYMMDGFPNSYVPTAFDTYHVTVEVNKKLCMIEFCDTAGQEDFDALRPLCYSSADVFIVCFSVVSPTSFANVASKWIPEIREFQPKAPIILVGTHSDLKDCYKILTELSQQDSQPISVKK-AEGLVKKTRCVCYVETSSVTQKNLKTVFDEAIISGYLPPKGGRT 200

[Close]

BLAST of SMED30034418 vs. Ensembl Medaka
Match: ENSORLT00000041989.1 (Rac family small GTPase 2 [Source:NCBI gene;Acc:101163549])

HSP 1 Score: 182.57 bits (462), Expect = 2.307e-54
Identity = 89/194 (45.88%), Postives = 134/194 (69.07%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + + ++ V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S AS+ N+++KW+PEV+++ P+TP+++VGTKLDL  +++KD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P+   +K K   CL+L
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWYPEVRHHCPSTPIILVGTKLDL--RDEKDTIEKLKEKKLAPITYPQGLALAKEIDAVKYLECSALTQRGLKTVFDEAIRAVLCPQ--PAKVKKANCLML 192

[Close]

BLAST of SMED30034418 vs. Ensembl Medaka
Match: ENSORLT00000038381.1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101175028])

HSP 1 Score: 182.185 bits (461), Expect = 3.589e-54
Identity = 93/195 (47.69%), Postives = 131/195 (67.18%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPET-RKSKSKPKFCLIL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ P TP+++VGTKLDL  ++DKD +   K+ +            +++I A+ Y+ECSA  ++     F+ A++AVL P   RK K K   C IL
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPVTPIILVGTKLDL--RDDKDTIEKLKEKKLSPIIYPQGLAMAKEISAVKYLECSALTQRGLKTVFDEAIRAVLCPPPDRKKKRK---CRIL 192

[Close]

BLAST of SMED30034418 vs. Ensembl Medaka
Match: RAC1 (ras-related C3 botulinum toxin substrate 1 [Source:NCBI gene;Acc:101159016])

HSP 1 Score: 178.333 bits (451), Expect = 1.115e-52
Identity = 84/177 (47.46%), Postives = 123/177 (69.49%), Query Frame = -2

Query:  117 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DK+     K+ +            +++I ++ Y+ECSA  ++     F+ A++AVL
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKETTEKLKEKKLSPITYPQGLAMAKEIGSVKYLECSALTQRGLKTVFDEAIRAVL 177

[Close]

Query:  117 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVE----------TFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVL 617
             IK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + +  + V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL S ASF N+++KW+PEV+++ PNTP+++VGTKLDL  ++DK+     K+ +            +++I ++ Y+ECSA  ++     F+ A++AVL
Sbjct:    3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL--RDDKETTEKLKEKKLSPITYPQGLAMAKEIGSVKYLECSALTQRGLKTVFDEAIRAVL 177

[Close]

BLAST of SMED30034418 vs. Ensembl Medaka
Match: ENSORLT00000007960.2 (cell division control protein 42 homolog [Source:NCBI gene;Acc:101164658])

HSP 1 Score: 177.948 bits (450), Expect = 7.605e-52
Identity = 89/192 (46.35%), Postives = 124/192 (64.58%), Query Frame = -2

Query:   66 IKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL---------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 614
            IK VV+GDG VGKTCLLI +  +K+   YVPT+FDN    + +G E   L L+DTAGQ+DYDRLRPLSYP +DVFL+CFS+ S +SF N++ KW PE+ ++ P TP ++VGT++DL         + KN +  LA     E  +R++KA+ Y+ECSA  ++     F+ A+ A L P   K K   K C++L
Sbjct:   55 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVREKWVPEISHHCPRTPFLLVGTQVDLRDDSNTLEKLAKNKQRALACESG-EKLARELKAVKYVECSALTQRGLKNVFDEAILAALEPPDTKPK---KRCVLL 242

[Close]

BLAST of SMED30034418 vs. Planmine SMEST
Match: SMESG000015187.1 (SMESG000015187.1)

HSP 1 Score: 379.022 bits (972), Expect = 1.147e-130
Identity = 184/184 (100.00%), Postives = 184/184 (100.00%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
            GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL
Sbjct:   12 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 195

[Close]

BLAST of SMED30034418 vs. Planmine SMEST
Match: SMESG000024961.1 (SMESG000024961.1)

HSP 1 Score: 181.8 bits (460), Expect = 2.977e-54
Identity = 84/184 (45.65%), Postives = 126/184 (68.48%), Query Frame = -2

Query:   90 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL--------ITKNDKDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKS 617
            GIK VV+GDG VGKTCLLI +  + +   Y+PT+FDN    + + N+ V+L LWDTAGQ+DYDRLRPLSYP +DVFL+CFSL + +S+ N+++KW+PE+ ++ PNTP+++VGTKLDL          K+ ++    +      +++I A+ Y+ECSA  +K     F+ A++AVL P+  + K+
Sbjct:    3 GIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLINSSSYENVRAKWYPEITHHCPNTPIILVGTKLDLRENHMNGEAGKDRRNTPISYPQGLVLAKEIGAVKYLECSALTQKGLKSVFDEAIRAVLCPKPPRKKT 186

[Close]

BLAST of SMED30034418 vs. Planmine SMEST
Match: SMESG000024968.1 (SMESG000024968.1)

HSP 1 Score: 180.644 bits (457), Expect = 9.471e-54
Identity = 86/187 (45.99%), Postives = 125/187 (66.84%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVET---FSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
            GIK VV+GDG VGKTCLLI +    +   Y+PT+FDN    + + N+ V+L LWDTAGQ+DYDRLRPLSYP +DVF++CFSL + +S+ N+++KW+PEV N+ PNTP+++VGTKLDL  ++  +    H          ++I A  Y+ECSA  +      F+ +++ VL P+ +++K   K C IL
Sbjct:    3 GIKCVVVGDGAVGKTCLLISYTTSAFPGEYIPTVFDNYSANIMVDNKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFIICFSLVNPSSYENVRAKWYPEVNNHCPNTPIILVGTKLDLRDESQTNKTGGHISYPQGLILMKEIGAKKYLECSALTQTGLKTVFDESIRVVLCPKQKQNK---KRCSIL 186

[Close]

BLAST of SMED30034418 vs. Planmine SMEST
Match: SMESG000005010.1 (SMESG000005010.1)

HSP 1 Score: 176.792 bits (447), Expect = 3.650e-52
Identity = 85/193 (44.04%), Postives = 128/193 (66.32%), Query Frame = -2

Query:   66 GIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDL-----ITKNDKDYL----ALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL 617
             IK VV+GDG VGKTC+LI +  D +   +VPT+FDN    + +    ++L LWDTAGQ++YDRLRPLSYP++DVFL+CFSL ++ SF N++ KW+ EV ++   TP+++VGTKLDL     + +NDK+ +      ++      ++I A+ YIECSAR + N    FE A++ V++ + + S  + KFC +L
Sbjct:    3 SIKCVVVGDGAVGKTCILISYTTDAFPTTHVPTVFDNMSANVMIEGTPINLGLWDTAGQEEYDRLRPLSYPETDVFLICFSLVNKDSFANVKEKWYKEVSHFSKETPIILVGTKLDLREERALNENDKNQIRSSPVTYQQGLALCQEIGAVKYIECSARTQVNLRQVFEEAIRVVIN-KPKPSNPRFKFCSLL 194

[Close]

BLAST of SMED30034418 vs. Planmine SMEST
Match: SMESG000001635.1 (SMESG000001635.1)

HSP 1 Score: 176.022 bits (445), Expect = 5.387e-52
Identity = 86/183 (46.99%), Postives = 123/183 (67.21%), Query Frame = -2

Query:   93 KIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKPTKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFNNIQSKWWPEVQNYKPNTPVVIVGTKLDLITKND----------KDYLALHKDVETFSRKIKAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSK 611
            K+V++GDG  GKTCLLI F+ D++ E+YVPT+F+N    +++ N+ V+L LWDTAGQ+DYDRLRPLSYPD+DV L+CFS++S  S  NI  KW+PEV+++ PN P+++VG K DL  +ND          +  L  ++D    + KI A+ Y+ECSA+ K      FE A +A L  + +K K
Sbjct:    7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDNKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSTDSLENIVEKWYPEVKHFCPNVPIILVGNKKDL--RNDERARHELAKMRQELVKYEDGLLTADKINAVKYLECSAKTKDGVREVFETATRAALSVKHKKKK 187

The following BLAST results are available for this feature:

BLAST of SMED30034418 vs. Ensembl Human
BLAST of SMED30034418 vs. Ensembl Celegans
BLAST of SMED30034418 vs. Ensembl Fly
BLAST of SMED30034418 vs. Ensembl Zebrafish
BLAST of SMED30034418 vs. Ensembl Xenopus
BLAST of SMED30034418 vs. Ensembl Mouse
BLAST of SMED30034418 vs. UniProt/SwissProt
BLAST of SMED30034418 vs. TrEMBL
BLAST of SMED30034418 vs. Ensembl Cavefish
BLAST of SMED30034418 vs. Ensembl Sea Lamprey
BLAST of SMED30034418 vs. Ensembl Yeast
BLAST of SMED30034418 vs. Ensembl Nematostella
BLAST of SMED30034418 vs. Ensembl Medaka
BLAST of SMED30034418 vs. Planmine SMEST

BLAST of SMED30034418 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RAC1	2.759e-55	46.91	Rac family small GTPase 1 [Source:HGNC Symbol;Acc:...	[more]
RAC2	7.843e-54	46.77	Rac family small GTPase 2 [Source:HGNC Symbol;Acc:...	[more]
RAC3	2.107e-53	48.02	Rac family small GTPase 3 [Source:HGNC Symbol;Acc:...	[more]
RAC1	1.403e-50	42.72	Rac family small GTPase 1 [Source:HGNC Symbol;Acc:...	[more]
CDC42	1.907e-50	45.41	cell division cycle 42 [Source:HGNC Symbol;Acc:HGN...	[more]

BLAST of SMED30034418 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mig-2	1.424e-58	49.48	Rac-like GTPase [Source:UniProtKB/TrEMBL;Acc:G5EB...	[more]
ced-10	1.246e-55	45.36	Ras-related protein ced-10 [Source:UniProtKB/Swis...	[more]
cdc-42	1.575e-49	45.70	Cell division control protein 42 homolog [Source:...	[more]
rac-2	9.074e-49	41.03	Ras-related protein rac-2 [Source:UniProtKB/Swiss...	[more]
rho-1	3.994e-47	44.25	Ras-like GTP-binding protein rhoA [Source:UniProt...	[more]

BLAST of SMED30034418 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mtl	2.371e-56	46.63	gene:FBgn0039532 transcript:FBtr0085192	[more]
Mtl	2.371e-56	46.63	gene:FBgn0039532 transcript:FBtr0085191	[more]
Mtl	2.371e-56	46.63	gene:FBgn0039532 transcript:FBtr0085193	[more]
RhoL	2.416e-54	44.81	gene:FBgn0014380 transcript:FBtr0082124	[more]
RhoL	7.927e-54	44.81	gene:FBgn0014380 transcript:FBtr0305340	[more]

BLAST of SMED30034418 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rac3b	1.193e-56	48.13	Rac family small GTPase 3b [Source:ZFIN;Acc:ZDB-GE...	[more]
rac3a	1.258e-56	48.13	Rac family small GTPase 3a [Source:ZFIN;Acc:ZDB-GE...	[more]
rac2	7.587e-55	45.88	Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GEN...	[more]
rac2	7.587e-55	45.88	Rac family small GTPase 2 [Source:ZFIN;Acc:ZDB-GEN...	[more]
rac1a	8.254e-55	46.91	Rac family small GTPase 1a [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of SMED30034418 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nab2	1.401e-55	47.59	NGFI-A binding protein 2 (EGR1 binding protein 2) ...	[more]
rac1	2.501e-55	46.91	Rac family small GTPase 1 [Source:NCBI gene;Acc:44...	[more]
rhogl.1	3.772e-55	45.08	ras homolog family member G like gene 1 [Source:NC...	[more]
yju2	3.903e-54	45.64	YJU2 splicing factor homolog [Source:Xenbase;Acc:X...	[more]
nab2	6.783e-52	45.70	NGFI-A binding protein 2 (EGR1 binding protein 2) ...	[more]

BLAST of SMED30034418 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rac1	1.894e-55	46.91	Rac family small GTPase 1 [Source:MGI Symbol;Acc:M...	[more]
Rac2	2.446e-54	45.21	Rac family small GTPase 2 [Source:MGI Symbol;Acc:M...	[more]
Rac3	1.447e-53	48.02	Rac family small GTPase 3 [Source:MGI Symbol;Acc:M...	[more]
Cdc42	1.309e-50	45.41	cell division cycle 42 [Source:MGI Symbol;Acc:MGI:...	[more]
Rac1	1.361e-50	42.72	Rac family small GTPase 1 [Source:MGI Symbol;Acc:M...	[more]

BLAST of SMED30034418 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6RUV5\|RAC1_RAT	1.325e-54	46.91	Ras-related C3 botulinum toxin substrate 1 OS=Ratt...	[more]
sp\|P63001\|RAC1_MOUSE	1.325e-54	46.91	Ras-related C3 botulinum toxin substrate 1 OS=Mus ...	[more]
sp\|P63000\|RAC1_HUMAN	1.325e-54	46.91	Ras-related C3 botulinum toxin substrate 1 OS=Homo...	[more]
sp\|P62999\|RAC1_CANLF	1.325e-54	46.91	Ras-related C3 botulinum toxin substrate 1 OS=Cani...	[more]
sp\|P62998\|RAC1_BOVIN	1.325e-54	46.91	Ras-related C3 botulinum toxin substrate 1 OS=Bos ...	[more]

BLAST of SMED30034418 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
B4NIG4	1.070e-56	49.18	Uncharacterized protein OS=Drosophila willistoni O...	[more]
G5EBV3	5.369e-55	49.48	Rac-like GTPase OS=Caenorhabditis elegans OX=6239 ...	[more]
A0A4T0FV37	7.218e-55	48.44	Uncharacterized protein OS=Wallemia hederae OX=154...	[more]
A8XQS8	7.690e-55	48.44	Protein CBR-MIG-2 OS=Caenorhabditis briggsae OX=62...	[more]
A0A2G5SP08	7.690e-55	48.44	Uncharacterized protein OS=Caenorhabditis nigoni O...	[more]

BLAST of SMED30034418 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rac3b	1.011e-56	48.13	ras-related C3 botulinum toxin substrate 3-like [S...	[more]
rac3a	1.066e-56	48.13	Rac family small GTPase 3 [Source:NCBI gene;Acc:10...	[more]
rac1b	1.073e-55	47.06	ras-related C3 botulinum toxin substrate 1-like [S...	[more]
rac1b	1.084e-55	47.06	ras-related C3 botulinum toxin substrate 1-like [S...	[more]
rac1b	1.084e-55	47.06	ras-related C3 botulinum toxin substrate 1-like [S...	[more]

BLAST of SMED30034418 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000009835.1	2.141e-54	48.02	pep scaffold:Pmarinus_7.0:GL479385:19931:31465:1 g...	[more]
ENSPMAT00000007368.1	1.877e-51	43.30	pep scaffold:Pmarinus_7.0:GL476419:214196:224439:-...	[more]
ENSPMAT00000002754.1	2.381e-51	44.74	pep scaffold:Pmarinus_7.0:GL476453:253767:255265:1...	[more]
ENSPMAT00000004439.1	2.674e-50	47.49	pep scaffold:Pmarinus_7.0:GL476335:1598569:1600956...	[more]
ENSPMAT00000001838.1	4.848e-49	47.16	pep scaffold:Pmarinus_7.0:GL478831:173097:182385:-...	[more]

BLAST of SMED30034418 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
CDC42	6.652e-50	45.03	Small rho-like GTPase; essential for establishment...	[more]
RHO4	5.965e-45	43.11	Non-essential small GTPase; member of the Rho/Rac ...	[more]
RHO1	3.671e-44	41.67	GTP-binding protein of the rho subfamily of Ras-li...	[more]
RHO5	2.093e-35	35.40	Non-essential small GTPase of the Rho/Rac family o...	[more]
RHO2	3.177e-35	38.50	Non-essential small GTPase of the Rho/Rac family o...	[more]

BLAST of SMED30034418 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO38536	2.298e-55	46.39	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37472	1.537e-52	45.95	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35019	1.861e-51	46.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39465	1.652e-49	47.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40156	2.184e-36	36.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SMED30034418 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000041989.1	2.307e-54	45.88	Rac family small GTPase 2 [Source:NCBI gene;Acc:10...	[more]
ENSORLT00000038381.1	3.589e-54	47.69	ras-related C3 botulinum toxin substrate 1 [Source...	[more]
RAC1	1.115e-52	47.46	ras-related C3 botulinum toxin substrate 1 [Source...	[more]
RAC1	1.115e-52	47.46	ras-related C3 botulinum toxin substrate 1 [Source...	[more]
ENSORLT00000007960.2	7.605e-52	46.35	cell division control protein 42 homolog [Source:N...	[more]

BLAST of SMED30034418 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000015187.1	1.147e-130	100.00	SMESG000015187.1	[more]
SMESG000024961.1	2.977e-54	45.65	SMESG000024961.1	[more]
SMESG000024968.1	9.471e-54	45.99	SMESG000024968.1	[more]
SMESG000005010.1	3.650e-52	44.04	SMESG000005010.1	[more]
SMESG000001635.1	5.387e-52	46.99	SMESG000001635.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034418 ID=SMED30034418|Name=SMED30034418|organism=Schmidtea mediterranea sexual|type=transcript|length=1623bp
TTTTTTTCTAAAAGTAAAAATTCTATTAAATAAATTGAAAAAATAAATGA
AATTCTTTTAAATCACAAAATGAGGCAAAATTTCGGTTTTGATTTCGATT
TCCTTGTTTCAGGATGTAGTACGGCTTTTACTGCTGCTTCAAATGGTAAT
GAGAAATTCTTCTTATCCCTTGCTGAACATTCAATGTAATCAATTGCTTT
AATTTTGCGAGAAAATGTTTCGACATCTTTGTGAAGTGCCAAATAGTCTT
TATCATTTTTTGTAATAAGATCTAATTTTGTTCCAACAATAACAACTGGA
GTGTTTGGTTTATAATTTTGAACTTCCGGCCACCATTTTGATTGAATATT
GTTGAAAGAAGCGCGGGATTCCAGTGAAAAACAAAGTAAAAACACATCAC
TATCGGGATATGAAAGGGGTCTTAATCGGTCGTAATCATCTTGTCCAGCA
GTATCCCAAAGATTCAAATCTACTACTTCATTGCCCAGTTTCATCTTGGT
GGGTTTATTGTCGAAAATGGTTGGTACGTAAAGTTCTTCGTATTTATCGT
CAGCAAATCGAATCAGCAAACACGTTTTCCCGACAGTCCCGTCGCCAATT
ACAACGATTTTAATTCCTTTCTCTTCTTTGGCTTTCATATTTTCATTCAT
TTTATAAATAAAAATATTTGATATGTAAAAGTTATTTTTCACAATTATGA
ATAAATGATAAATTAGCCACTTGAAAAATATGAACCATAAATTCTGATCT
TTGTCATTCGTTATTTTTATCGAGAATTATTAACTTCTAAATAGTCCTGA
TTTAATTATGCAGTGCCTCCATTTCATGAAACCAATTTTTTATATATAAA
TTATTTTACTAGAACAATTTCTTTGGGCACTTGGTCTGAGCCTCCTTTCT
GCTTCGATAATCTCTTCCATTATACTTGACTTTTATTAGATCTGTAAGTC
CAAGGTTTCGAGTCCAGTCCAGCAGAATGTATTGTGACATCCAAGTTCAT
CAAGTTTAACTGATTTGTTCTTGTTTGTTGAGAAAATTGAAAAACCATTC
AATTTCAGGAGGTTGTGGACTACAAAGTTTGGAGGCTGAATTGCCGTAAT
ATTTGGACTGATATTATCCCCAAAATAATTCGACCCAAACCTAAATAAAA
TGTAGAAAAAGAAATAATATTCTATTTAAACATTTTATAGTTACCATGGA
TAGGATAATGATTTGCCAATTTAGAGTCTAACAAGTAAAAAATATTACAT
TTTGGGTTTTGGCTACTTTTTCTTGGTCATTTGGCAGATGTGAACTTAAA
TTTTTTTGATAAAGATCTTTGATCTTTGGCCAATCACGTTATTCAAAAAT
ACATATGAAACCAATATTTTTAATTTAATTTAAAATAGACTGTTTAAAAC
TATTAGAATTTAGCATGTGCAATATCTTTTCTACAGTAATTTATGAATGC
CGTTTAGTCGGAATTAATTATTTCTTGAGATACCATATATATTTGTAATA
ACAAGCAATAAGCAATTTTTATTTAATAAAAATTTGAATTATAATTTTGC
GTGTGAAACACAATATTTAAACAAATATATTATTAAAATATTATAATTTT
AGCACTAATCGAAACCTTTGGAG

protein sequence of SMED30034418-orf-1

>SMED30034418-orf-1 ID=SMED30034418-orf-1|Name=SMED30034418-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=196bp
MNENMKAKEEKGIKIVVIGDGTVGKTCLLIRFADDKYEELYVPTIFDNKP
TKMKLGNEVVDLNLWDTAGQDDYDRLRPLSYPDSDVFLLCFSLESRASFN
NIQSKWWPEVQNYKPNTPVVIVGTKLDLITKNDKDYLALHKDVETFSRKI
KAIDYIECSARDKKNFSLPFEAAVKAVLHPETRKSKSKPKFCLIL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR005225	Small_GTP-bd_dom
IPR003578	Small_GTPase_Rho
IPR027417	P-loop_NTPase
IPR001806	Small_GTPase

Vocabulary: **molecular function**
Term	Definition
GO:0003924	GTPase activity
GO:0005525	GTP binding

Vocabulary: **biological process**
Term	Definition
GO:0007264	small GTPase mediated signal transduction

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00449	RASTRNSFRMNG	coord: 115..128 score: 44.59 coord: 13..34 score: 51.95 coord: 36..52 score: 26.59 coord: 53..75 score: 37.32 coord: 155..177 score: 29.6
None	No IPR available	SMART	SM00175	rab_sub_5	coord: 13..180 e-value: 6.8E-18 score: 75.4
None	No IPR available	SMART	SM00174	rho_sub_3	coord: 15..180 e-value: 1.6E-77 score: 273.6
None	No IPR available	SMART	SM00176	ran_sub_2	coord: 18..191 e-value: 0.0054 score: -5.4
None	No IPR available	SMART	SM00173	ras_sub_4	coord: 10..180 e-value: 6.1E-13 score: 59.0
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 11..193 e-value: 1.5E-54 score: 186.2
None	No IPR available	PANTHER	PTHR24072	RHO FAMILY GTPASE	coord: 10..186
None	No IPR available	CDD	cd00157	Rho	coord: 13..176 e-value: 2.92544E-77 score: 227.042
IPR005225	Small GTP-binding protein domain	TIGRFAM	TIGR00231	TIGR00231	coord: 11..167 e-value: 1.5E-32 score: 110.6
IPR001806	Small GTPase	PFAM	PF00071	Ras	coord: 14..178 e-value: 6.5E-49 score: 165.6
IPR003578	Small GTPase Rho	PROSITE	PS51420	RHO	coord: 6..192 score: 21.108
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 12..178