Thyrotropin-releasing hormone receptor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30034409 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Human
Match: TRHR (thyrotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:12299]) HSP 1 Score: 207.223 bits (526), Expect = 2.116e-62 Identity = 129/333 (38.74%), Postives = 195/333 (58.56%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLK---YRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN-------------KKDSKLR----IVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F LY W +L L Y+++ + S C Y+++ Y +YL D +FY+ P+I+ +VLY I L LN K DS + V + V S+ +V KML VV+LFA+LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C+Q + K Y
Sbjct: 24 YQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD--SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVIS------CGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANY 348
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Human
Match: TRHR (thyrotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:12299]) HSP 1 Score: 207.223 bits (526), Expect = 2.116e-62 Identity = 129/333 (38.74%), Postives = 195/333 (58.56%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLK---YRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN-------------KKDSKLR----IVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F LY W +L L Y+++ + S C Y+++ Y +YL D +FY+ P+I+ +VLY I L LN K DS + V + V S+ +V KML VV+LFA+LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C+Q + K Y
Sbjct: 24 YQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD--SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVIS------CGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANY 348
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Human
Match: HCRTR2 (hypocretin receptor 2 [Source:HGNC Symbol;Acc:HGNC:4849]) HSP 1 Score: 100.523 bits (249), Expect = 1.249e-22 Identity = 101/380 (26.58%), Postives = 182/380 (47.89%), Query Frame = 1
Query: 52 MNDTST---SDISYPIAQFITVLY----YSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADM---ITLLSSILPV-ISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFN-LLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPE-YLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-----------LNKKDSKLRIVGKK-------------FXXXXXXXXXXXXXXXXXXTVVVLFAVLWLP-------YRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQE 1059
+N+T + Y +F+ L+ + Y+ + +++ + +IGN LV + V+ + M T TN F+V+LS+AD+ IT L + L V I+E W F LC + +LQ S + S ++++C + +RW AIC PL + T RA I IW+ + ++ + + N + L VC R E Y ++ ++C ++ Y+ PL + + Y+ I L + +K L+ V + E K ++++ K +ML+ V+++FA+ +LP R + ++ +++ + WF F+ +VY NSA NPI+YN +S KFR+ FK++ +C + QE
Sbjct: 21 LNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET------WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFK--STAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFT-FSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQE 391
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Human
Match: HCRTR2 (hypocretin receptor 2 [Source:HGNC Symbol;Acc:HGNC:4849]) HSP 1 Score: 100.523 bits (249), Expect = 1.249e-22 Identity = 101/380 (26.58%), Postives = 182/380 (47.89%), Query Frame = 1
Query: 52 MNDTST---SDISYPIAQFITVLY----YSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADM---ITLLSSILPV-ISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFN-LLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPE-YLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-----------LNKKDSKLRIVGKK-------------FXXXXXXXXXXXXXXXXXXTVVVLFAVLWLP-------YRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQE 1059
+N+T + Y +F+ L+ + Y+ + +++ + +IGN LV + V+ + M T TN F+V+LS+AD+ IT L + L V I+E W F LC + +LQ S + S ++++C + +RW AIC PL + T RA I IW+ + ++ + + N + L VC R E Y ++ ++C ++ Y+ PL + + Y+ I L + +K L+ V + E K ++++ K +ML+ V+++FA+ +LP R + ++ +++ + WF F+ +VY NSA NPI+YN +S KFR+ FK++ +C + QE
Sbjct: 21 LNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET------WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFK--STAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFT-FSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQE 391
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Human
Match: BRS3 (bombesin receptor subtype 3 [Source:HGNC Symbol;Acc:HGNC:1113]) HSP 1 Score: 99.3673 bits (246), Expect = 1.980e-22 Identity = 86/304 (28.29%), Postives = 156/304 (51.32%), Query Frame = 1
Query: 145 INLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYN-SSWLYLTTLKYRESYINSSILNPVCT-YRLNPEYLRIVY--LCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLD-----LWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTC 1029
I VI+S+GI+GN +++ V + ++ M T N F+ SL+ D++ LL+ + PV H W F C + F++ S S ++T S +R+ A+ KPL Q + + +W+ ++++ ++ +R+ N ++ CT Y ++ + L+ ++ LC ++FYI PL + SV Y I TL S L I ++ K ++S+ ++ + ++ +V LFA+ WLP +Y+SF + Y+D F +F+R + + NS +NP +S F+K FK+ L C
Sbjct: 52 ITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCV-PV-DATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDP--NKNMTFESCTSYPVSKKLLQEIHSLLC-FLVFYIIPLSIISVYYSLIARTLYK---STLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFC 347
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Celegans
Match: trhr-1 (Thyrotropin-Releasing Hormone Receptor [Source:UniProtKB/TrEMBL;Acc:Q95YD7]) HSP 1 Score: 181.415 bits (459), Expect = 5.980e-53 Identity = 113/320 (35.31%), Postives = 180/320 (56.25%), Query Frame = 1
Query: 169 LGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRL--NPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLN-----KKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXT---------------------VVVLFAVLWLPYRSWIVYNSF-AEKKY--LDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQ 1035
+G++GN LV+ VV RGM TPTNC+LVSL+ +D + +S+ + +++ F C + +L + + N S++SI F+ ER+ IC P A+ MCT+ RA II GIW+F++LY+S WL+L TL + + C++RL N +IV+L D +++Y+ P++ ++Y I +TL KK K +I + V++SK + + + VV +FAV WLPYR +VYNSF ++ KY W++ ++++V++N AINPILYN MSA+FR AF+S L+ R+
Sbjct: 45 IGVLGNLLVITVVLKVRGMKTPTNCYLVSLAASDTLFFFASMPHEMMYLLGPNDHYLFGSLGCVLLTYLPYLAMNTSSLSILAFTIERYYGICNPYKARTMCTVKRATCIICGIWIFSMLYHSYWLFLATLIKDD-------IGTSCSFRLERNSHAYKIVFLLDFVLWYVLPIMCDIIIYAKIGITLSQCGDKIKKSVKPKIPNEVIVEKSKTSSTSMGHYSGRDSHISGKRNSAKGRNQVVKMLAIVVAVFAVCWLPYRGMVVYNSFVSDPKYSWSPDWYINLSKTLVFINCAINPILYNLMSARFRAAFRSLLSKRK 357
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Celegans
Match: nmur-2 (NMUR (NeuroMedin U Receptor) homolog [Source:UniProtKB/TrEMBL;Acc:O17239]) HSP 1 Score: 114.775 bits (286), Expect = 3.145e-28 Identity = 104/340 (30.59%), Postives = 167/340 (49.12%), Query Frame = 1
Query: 133 IIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNY---WRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNL---LYNSSWLYLTTLKYRESYINSSILNPVCTYRL-------------NPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPY---RSWIVYNSFAEK-------KYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEYL 1065
I GTI L LG+ GN IV+ ++ MH PTN +L SL+++D+I L IL + E++ ++Y +RF+ +C FL ++ AS M I CFSFERW+AIC PL +++ TL RA +I W + L + + + L E N V T + P+ +++ + +F++ P I ++Y I + L + S++ + G K + + KS V+KML++VV+ F + WLP+ R VY +++E ++L + + Y NSA NPILYN +S K+R AF CR I ++
Sbjct: 37 IYGTIFL-----LGLFGNICTCIVIAANKSMHNPTNYYLFSLAVSDIIAL---ILGLPMEFYQSLDYSYPYRFSEGICKARAFLIEFTSYASIMIICCFSFERWLAICHPLRSKIFSTLWRANVLIILAWTISFVCALPIAFIVQINKLPLPEDAKYQPWTNKVSTDGIFVLHTEFCAMNQSRPDQQKMIIIFAFTVFFVIPAIAIVIMYAHIAVQL---ESSEIDLKGDKM-VKKRRNKSNRTVLKMLLSVVITFFICWLPFHIQRLLSVYTTWSETTTISPPVQFLSMIVFYISGFCYYSNSAANPILYNILSQKYRSAF-----CRTILGDHIANFV 359
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Celegans
Match: npr-24 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q23033]) HSP 1 Score: 89.7373 bits (221), Expect = 1.254e-19 Identity = 89/345 (25.80%), Postives = 150/345 (43.48%), Query Frame = 1
Query: 169 LGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLY---------------------NSSWLYLTTLKYRES--YINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKD--SKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVY-----NSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTC----RQIFSSKAQEYLDCSEMKDPSGNP 1101
+GI N V+ + + R M T +N ++ +L++AD++ L +PV S + W + P +C + + S ASA+ I SF+R++A+C+P+ ++ T A + W+ +L S L++ + ES +N ++LN + L I Y + Y+ PL+ Y I+L + +K R KK KV M + +V+ + WLP+ WIV N F + KYL FA ++ Y+NSA NP LY +S F+K + L +QI + + D S+M + + NP
Sbjct: 31 IGIPANLFVLAAIVYFRDMRTISNIYIFNLAVADLLFLCG--IPVSLFAQSSHDGWIWGPIMCKLYISGNAVSQFASAVFIAILSFDRYLAVCRPIQSKSFRTTQAAFALSVAAWIMVILEMTPLFLFVKLIKSSSAGEARGGSCMLFVGNVTVLESATEMNETLLNEIEQNMLASRRFFISY--TFALSYLIPLVAVWYFYFKIILKMCQRKRQMQTKRTATKK---------RTTKVTIMGLAIVISYTHCWLPF--WIVQWSIEANLFEKSKYLLFCCTHFAFALQYINSAANPFLYVFLSDSFQKNIQKLLRTAKPDKQIMLKNSTDPQDTSKMLNVTNNP 360
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Celegans
Match: npr-22 (Neuropeptide receptor 22 [Source:UniProtKB/Swiss-Prot;Acc:Q59E83]) HSP 1 Score: 82.0333 bits (201), Expect = 7.235e-17 Identity = 93/350 (26.57%), Postives = 160/350 (45.71%), Query Frame = 1
Query: 34 TTFPQTMNDTSTSDISYPIAQFITVLYYSNIYKIIGTINLMVILSLGII------GNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNY----WRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCT-----YRLNPEYLRIVYLCD-LIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAE--------KKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAF 1011
TT + M + P Q + ++IY + ++ ++ IL I+ GN LV++V+ + + + T TN +++L++AD LL S+ + Y + Y W F +C + FLQ + SA ++ SF+RWMAI LT + T RA+ ++ W+F++L L+ T + + P C + + E +R VY LI+ Y+ P V + Y I + + N + ++ G +S K++ M+I + LFA+ WLP I+ N E L LW+ FA + +S +NPI+Y +A+FR+ F
Sbjct: 17 TTASEIMMRNEPTTTENPAVQEM-----NHIYHLTPSMKMLCILFYSILCVCCVYGNVLVILVIVYFKRLRTATNILILNLAVAD---LLISVFCIPFSYWQVLIYDDQRWLFGSMMCSLLAFLQAMAVFLSAWTLVVISFDRWMAIMFLLTPNIRITRRRALYLVAATWIFSILMALPLLFTTRFFEDQDGL------PNCGENWTYFGDSGEQVRKVYSSMVLILQYVVPQAVLIITYTHIGIKMWNSRVPGMQ-NGATKKMIVDRHESVKKLVPMVILISALFALCWLPLL--ILINVIPEFYPDINSWGYILYLWW--FAHGLAMSHSMVNPIIYFIRNARFREGF 347
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Celegans
Match: npr-22 (Neuropeptide receptor 22 [Source:UniProtKB/Swiss-Prot;Acc:Q59E83]) HSP 1 Score: 81.6481 bits (200), Expect = 9.487e-17 Identity = 93/352 (26.42%), Postives = 161/352 (45.74%), Query Frame = 1
Query: 28 LITTFPQTMNDTSTSDISYPIAQFITVLYYSNIYKIIGTINLMVILSLGII------GNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNY----WRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCT-----YRLNPEYLRIVYLCD-LIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAE--------KKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAF 1011
+ TT + M + P Q + ++IY + ++ ++ IL I+ GN LV++V+ + + + T TN +++L++AD LL S+ + Y + Y W F +C + FLQ + SA ++ SF+RWMAI LT + T RA+ ++ W+F++L L+ T + + P C + + E +R VY LI+ Y+ P V + Y I + + N + ++ G +S K++ M+I + LFA+ WLP I+ N E L LW+ FA + +S +NPI+Y +A+FR+ F
Sbjct: 15 ITTTASEIMMRNEPTTTENPAVQEM-----NHIYHLTPSMKMLCILFYSILCVCCVYGNVLVILVIVYFKRLRTATNILILNLAVAD---LLISVFCIPFSYWQVLIYDDQRWLFGSMMCSLLAFLQAMAVFLSAWTLVVISFDRWMAIMFLLTPNIRITRRRALYLVAATWIFSILMALPLLFTTRFFEDQDGL------PNCGENWTYFGDSGEQVRKVYSSMVLILQYVVPQAVLIITYTHIGIKMWNSRVPGMQ-NGATKKMIVDRHESVKKLVPMVILISALFALCWLPL--LILINVIPEFYPDINSWGYILYLWW--FAHGLAMSHSMVNPIIYFIRNARFREGF 347
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Fly
Match: ETHR (gene:FBgn0038874 transcript:FBtr0084054) HSP 1 Score: 143.665 bits (361), Expect = 4.264e-38 Identity = 104/296 (35.14%), Postives = 163/296 (55.07%), Query Frame = 1
Query: 154 MVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRS---WIVYNSFAEKKYLDLWFVL------FARSMVYVNSAINPILYNAMSAKFRKAFK 1014
+VI+ LG++GN +V IV+ ++ M TN FL +LSIAD++ LL V+ E +++ W E+C F++ A+AS ++I SFER+ AIC+PL A +CT RA+ I W L+ S L++ K E YI+ S + VC + ++ +L + +F++ P + VLY I L++ + + LR K +K++ +V+ ML VV+ F V LP+R WI+ ++ ++ DL V F R M+Y+NSA+NPILYN MS KFR+ FK
Sbjct: 18 IVIMLLGVVGNVMVPIVIVKTKDMRNSTNIFLTNLSIADLLVLLVCTPTVLVEVNTRPETWVLGHEMCKAVPFVELTVAHASVLTILAISFERYYAICEPLKAGYVCTKGRAILICVLAWGIAALFTSPILWVAEYKLAE-YIDGSSV-AVCLTQAISDWTLAFFLMTISVFFVVPFVTLVVLYGIIARNLVSNRAAMLRARPTK---PELSLKARKQVVLMLGAVVLSFFVCLLPFRVLTLWIILST--DQTLHDLGLVRYYSLLYFCRIMLYLNSAMNPILYNLMSTKFRRGFK 306
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Fly
Match: ETHR (gene:FBgn0038874 transcript:FBtr0339194) HSP 1 Score: 143.665 bits (361), Expect = 4.264e-38 Identity = 104/296 (35.14%), Postives = 163/296 (55.07%), Query Frame = 1
Query: 154 MVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRS---WIVYNSFAEKKYLDLWFVL------FARSMVYVNSAINPILYNAMSAKFRKAFK 1014
+VI+ LG++GN +V IV+ ++ M TN FL +LSIAD++ LL V+ E +++ W E+C F++ A+AS ++I SFER+ AIC+PL A +CT RA+ I W L+ S L++ K E YI+ S + VC + ++ +L + +F++ P + VLY I L++ + + LR K +K++ +V+ ML VV+ F V LP+R WI+ ++ ++ DL V F R M+Y+NSA+NPILYN MS KFR+ FK
Sbjct: 18 IVIMLLGVVGNVMVPIVIVKTKDMRNSTNIFLTNLSIADLLVLLVCTPTVLVEVNTRPETWVLGHEMCKAVPFVELTVAHASVLTILAISFERYYAICEPLKAGYVCTKGRAILICVLAWGIAALFTSPILWVAEYKLAE-YIDGSSV-AVCLTQAISDWTLAFFLMTISVFFVVPFVTLVVLYGIIARNLVSNRAAMLRARPTK---PELSLKARKQVVLMLGAVVLSFFVCLLPFRVLTLWIILST--DQTLHDLGLVRYYSLLYFCRIMLYLNSAMNPILYNLMSTKFRRGFK 306
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Fly
Match: ETHR (gene:FBgn0038874 transcript:FBtr0084053) HSP 1 Score: 127.872 bits (320), Expect = 1.895e-32 Identity = 102/322 (31.68%), Postives = 164/322 (50.93%), Query Frame = 1
Query: 154 MVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIV----------------------GKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRS---WIVYNSFAEKKYLDLW----FVLFARSMVYVNSAINPILYNAMSAKFRKAF-KSSLTC 1029
+VI+ LG++GN +V IV+ ++ M TN FL +LSIAD++ LL V+ E +++ W E+C F++ A+AS ++I SFER+ AIC+PL A +CT RA+ I W L+ S + ++T E Y + + PVCT + + ++ + +F+ P + +LY I LL ++ R G + + + K + +VI ML+ VV F V LP+R+ W++ S + + L + + F+R M+Y+NSA+NPILYN MS+KFR F + LTC
Sbjct: 18 IVIMLLGVVGNVMVPIVIVKTKDMRNSTNIFLTNLSIADLLVLLVCTPTVLVEVNTRPETWVLGHEMCKAVPFVELTVAHASVLTILAISFERYYAICEPLKAGYVCTKGRAILICVLAWGIAALFTSPIIAISTYSV-EPYGDGTDA-PVCTTAADGFWSIFYFVGCITVFFFLPFGILVLLYAAIAYKLLRPNNAFHRPTSPQPQQPSGGATSGSSQVPSTKGNSHQQSNGMRKHRKQVIFMLVAVVSSFFVCLLPFRAFTLWVILASAEDVEGLGIAGYYNLLYFSRFMLYLNSAMNPILYNLMSSKFRSGFWRLLLTC 337
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Fly
Match: PK2-R1 (gene:FBgn0038140 transcript:FBtr0082745) HSP 1 Score: 106.301 bits (264), Expect = 1.647e-24 Identity = 94/305 (30.82%), Postives = 156/305 (51.15%), Query Frame = 1
Query: 172 GIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYW-----RFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFN-LLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPY---RSWIVYN------SFAEKKYLDLWFVLFARSMV--YVNSAINPILYNAMSAKFRKAFKSSLTCRQ 1035
G++GN + IV+ + MHT TN +L +L+++D+I L+S I + N W F +C + L +ANA+ ++IT F+ ER++AIC P M L+RA+K IF IW+ LL + + + E Y CT + ++ V+ IF+ P+ VLY+ I + L K+ L+ + ++ ++ + ++ +VI+ML+ V V F + W P+ R VY + + D + +L S V ++++ INP+LYN MS KFR+AFK +LT RQ
Sbjct: 121 GVLGNLITCIVISRNNFMHTATNFYLFNLAVSDLILLVSGIPQEL------YNLWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVYQNEGY--------SCT--MENDFYAHVFAVSGFIFFGGPMTAICVLYVLIGVKL--KRSRLLQSLPRRTFDANRGLNAQGRVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKITLT-RQ 406
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Fly
Match: CapaR (gene:FBgn0037100 transcript:FBtr0078379) HSP 1 Score: 102.449 bits (254), Expect = 1.659e-23 Identity = 87/300 (29.00%), Postives = 147/300 (49.00%), Query Frame = 1
Query: 175 IIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPEL-----CPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLR--IVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRI-VGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAE--KKYLDLWFVLF--ARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQI 1038
++GN LV IV+ MHT TN +L SL+++D++ LL LP YW P+L C I F+ S +I FS ER++AIC PL M RA++II +W+ + + + L+ ++Y ++ S + ++P+ + V+ IF++ P+I+ +LY + + ++ + KL + G + K VI+ML VV+ F V W P+ + +A+ YLD+ LF A YV+ +NPI+Y+ MS ++R AF+ L + +
Sbjct: 83 VVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFG-LPT-----EVFLYWHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIVNEIPVFEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYRVAFRELLCGKAV 376
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: trhra (thyrotropin-releasing hormone receptor a [Source:ZFIN;Acc:ZDB-GENE-100922-18]) HSP 1 Score: 221.09 bits (562), Expect = 3.830e-68 Identity = 135/313 (43.13%), Postives = 195/313 (62.30%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
YK++ + +++I +GI+GN +V++VV ++ M TPTNC+LVSL++AD++ L ++ LP I+E W + C + Q+ NAS+ SIT F+ ER++AIC P+ AQ MCTL+RA KII +WV LY W YL L RE ++++L C Y+++ E +Y D +FY+ PL++ +VLY I L LN S + + + KES V S+ +V KML VV+LFA+LW+PYR+ +V NSF ++ YLD F+LF R +Y+NSAINPI+YNAMS KFR AF CR S K Y
Sbjct: 18 YKVVSILLVILICGVGIVGNVMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPNITEILFG-GQWVYGYAGCLSITYFQYLGINASSCSITAFTIERYIAICHPIKAQFMCTLSRAKKIIVLVWVLTSLYCVMWFYL--LDTREKVYDNAVL-VTCGYKVSRELYLPIYFTDYAVFYVIPLLLATVLYGLIARILFLNPLPSDPKESRRNWKKESTTVASRRQVTKMLAVVVILFALLWMPYRTLVVVNSFLKEAYLDTCFLLFCRLCIYMNSAINPIIYNAMSQKFRAAFHKLCHCRPQRSEKPPAY 326
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: trhrb (thyrotropin-releasing hormone receptor b [Source:ZFIN;Acc:ZDB-GENE-060503-382]) HSP 1 Score: 217.624 bits (553), Expect = 1.458e-66 Identity = 133/326 (40.80%), Postives = 195/326 (59.82%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN--KKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXT-------------VVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTC-RQIFSSKA 1053
YK I + + +I +LGI+GN +V++VV ++ M TPTN +LVSL++AD++ L+++ LP I++ S W F C + Q+ NAS+ SIT F+ ER++AIC P+ AQ +CTL+RA KII G+WVF LY W YL+ ++ + Y +++I+ C Y+++ +Y D IF++ PL + +VLY I L LN D+K G ++K K K T VV+LFAVLW+PYR+ +V NSF + YLD WF+LF R+ VY+NSAINP++YNAMS KFR AF+ C R ++KA
Sbjct: 21 YKAISVLIVFLICALGIVGNVMVILVVLTTKHMRTPTNGYLVSLAVADLMVLVAAGLPSIAD--SLFGSWVFGHAGCLCITYFQYLGINASSCSITAFTIERYIAICHPIKAQFLCTLSRAKKIIIGVWVFTSLYCVMWFYLSDVQ-QVLYKDATII--TCAYKVSRNLYLPIYFFDFGIFFVLPLTLATVLYGLIARILFLNPLPSDTKEEKNGHGNFSKAKRNKLKSSSRCSSTTAASRRQVTKMLAVVVILFAVLWMPYRTLVVVNSFLQDAYLDTWFLLFCRTCVYLNSAINPLIYNAMSQKFRAAFRRLCRCGRNAQANKA 341
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: trhra (thyrotropin-releasing hormone receptor a [Source:ZFIN;Acc:ZDB-GENE-100922-18]) HSP 1 Score: 212.231 bits (539), Expect = 1.054e-64 Identity = 135/326 (41.41%), Postives = 195/326 (59.82%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN-------------KKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
YK++ + +++I +GI+GN +V++VV ++ M TPTNC+LVSL++AD++ L ++ LP I+E W + C + Q+ NAS+ SIT F+ ER++AIC P+ AQ MCTL+RA KII +WV LY W YL L RE ++++L C Y+++ E +Y D +FY+ PL++ +VLY I L LN KK+S + + S V S+ +V KML VV+LFA+LW+PYR+ +V NSF ++ YLD F+LF R +Y+NSAINPI+YNAMS KFR AF CR S K Y
Sbjct: 18 YKVVSILLVILICGVGIVGNVMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPNITEILFG-GQWVYGYAGCLSITYFQYLGINASSCSITAFTIERYIAICHPIKAQFMCTLSRAKKIIVLVWVLTSLYCVMWFYL--LDTREKVYDNAVL-VTCGYKVSRELYLPIYFTDYAVFYVIPLLLATVLYGLIARILFLNPLPSDPKESRRNWKKESSVHGN-SRSSSNSTTVASRRQVTKMLAVVVILFALLWMPYRTLVVVNSFLKEAYLDTCFLLFCRLCIYMNSAINPIIYNAMSQKFRAAFHKLCHCRPQRSEKPPAY 338
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: trhra (thyrotropin-releasing hormone receptor a [Source:ZFIN;Acc:ZDB-GENE-100922-18]) HSP 1 Score: 212.616 bits (540), Expect = 1.195e-64 Identity = 127/325 (39.08%), Postives = 191/325 (58.77%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL------NKKDSKLR------IVGKKFXXXXXXXXXXXXXXXXXXTVVV-LFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
YK++ + +++I +GI+GN +V++VV ++ M TPTNC+LVSL++AD++ L ++ LP I+E W + C + Q+ NAS+ SIT F+ ER++AIC P+ AQ MCTL+RA KII +WV LY W YL L RE ++++L C Y+++ E +Y D +FY+ PL++ +VLY I L + K+S+ + G + + + + ++ VVV LFA+LW+PYR+ +V NSF ++ YLD F+LF R +Y+NSAINPI+YNAMS KFR AF CR S K Y
Sbjct: 22 YKVVSILLVILICGVGIVGNVMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPNITEILFG-GQWVYGYAGCLSITYFQYLGINASSCSITAFTIERYIAICHPIKAQFMCTLSRAKKIIVLVWVLTSLYCVMWFYL--LDTREKVYDNAVL-VTCGYKVSRELYLPIYFTDYAVFYVIPLLLATVLYGLIARILFLNPLPSDPKESRRNWKKESSVHGNSRSSSNSTTVASRRQVTKMLAVVVILFALLWMPYRTLVVVNSFLKEAYLDTCFLLFCRLCIYMNSAINPIIYNAMSQKFRAAFHKLCHCRPQRSEKPPAY 342
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Zebrafish
Match: trhra (thyrotropin-releasing hormone receptor a [Source:ZFIN;Acc:ZDB-GENE-100922-18]) HSP 1 Score: 212.231 bits (539), Expect = 1.332e-64 Identity = 127/325 (39.08%), Postives = 191/325 (58.77%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL------NKKDSKLR------IVGKKFXXXXXXXXXXXXXXXXXXTVVV-LFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
YK++ + +++I +GI+GN +V++VV ++ M TPTNC+LVSL++AD++ L ++ LP I+E W + C + Q+ NAS+ SIT F+ ER++AIC P+ AQ MCTL+RA KII +WV LY W YL L RE ++++L C Y+++ E +Y D +FY+ PL++ +VLY I L + K+S+ + G + + + + ++ VVV LFA+LW+PYR+ +V NSF ++ YLD F+LF R +Y+NSAINPI+YNAMS KFR AF CR S K Y
Sbjct: 18 YKVVSILLVILICGVGIVGNVMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPNITEILFG-GQWVYGYAGCLSITYFQYLGINASSCSITAFTIERYIAICHPIKAQFMCTLSRAKKIIVLVWVLTSLYCVMWFYL--LDTREKVYDNAVL-VTCGYKVSRELYLPIYFTDYAVFYVIPLLLATVLYGLIARILFLNPLPSDPKESRRNWKKESSVHGNSRSSSNSTTVASRRQVTKMLAVVVILFALLWMPYRTLVVVNSFLKEAYLDTCFLLFCRLCIYMNSAINPIIYNAMSQKFRAAFHKLCHCRPQRSEKPPAY 338
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: ENSXETT00000016751.1 (thyrotropin-releasing hormone receptor 3 [Source:NCBI gene;Acc:100489565]) HSP 1 Score: 209.92 bits (533), Expect = 1.565e-63 Identity = 136/339 (40.12%), Postives = 196/339 (57.82%), Query Frame = 1
Query: 151 LMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYL---TTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL------NKKD-------------SKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY---LDCSEMKDPS 1092
+++I +GI GN +VV+VV ++ M TPTNC+LVSL+IAD+I LL++ LP ISE + W + C +LQ+ N SA SIT F+ ER++AIC + AQ +CT++RA KII +W F +Y W +L T +K+ + + C YR++ +Y D IFY+ PL++ +VLY I L N +D + +++ GK S+ +V KML VV+LFA+LW+PYR+ +V NSF + YL++WFVLF R +Y+NSAINPI+YN MS KFR AFK+ C Q + KA +Y + S MKD S
Sbjct: 40 VLLICGVGIAGNIMVVLVVLRTKHMMTPTNCYLVSLAIADLIVLLAAGLPNISEVVAS---WVYGYVGCLCITYLQYLGINISACSITAFTVERYIAICHSIKAQFICTVSRAKKIIAFVWFFTSMYCVMWFFLVDITEVKFADG------VQVNCGYRVSRNLYTPIYFLDFTIFYVIPLVLATVLYGLIARILFMNPLPSNPQDLSRMSSKHYGKPYNSIKLSGKG---NKNTASSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFMDPPYLNVWFVLFCRLCIYLNSAINPIIYNLMSQKFRAAFKNLCKCEQKRTEKAAKYNVPVYYSVMKDSS 366
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: ENSXETT00000016730.1 (thyrotropin-releasing hormone receptor 3 [Source:NCBI gene;Acc:100489565]) HSP 1 Score: 209.534 bits (532), Expect = 1.656e-63 Identity = 135/336 (40.18%), Postives = 195/336 (58.04%), Query Frame = 1
Query: 151 LMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL------NKKD-------------SKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY---LDCSEMKDPS 1092
+++I +GI GN +VV+VV ++ M TPTNC+LVSL+IAD+I LL++ LP ISE + W + C +LQ+ N SA SIT F+ ER++AIC + AQ +CT++RA KII +W F +Y W +L + + + +N C YR++ +Y D IFY+ PL++ +VLY I L N +D + +++ GK S+ +V KML VV+LFA+LW+PYR+ +V NSF + YL++WFVLF R +Y+NSAINPI+YN MS KFR AFK+ C Q + KA +Y + S MKD S
Sbjct: 22 VLLICGVGIAGNIMVVLVVLRTKHMMTPTNCYLVSLAIADLIVLLAAGLPNISEVVAS---WVYGYVGCLCITYLQYLGINISACSITAFTVERYIAICHSIKAQFICTVSRAKKIIAFVWFFTSMYCVMWFFLVDIT-EVKFADGVQVN--CGYRVSRNLYTPIYFLDFTIFYVIPLVLATVLYGLIARILFMNPLPSNPQDLSRMSSKHYGKPYNSIKLSGKG---NKNTASSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFMDPPYLNVWFVLFCRLCIYLNSAINPIIYNLMSQKFRAAFKNLCKCEQKRTEKAAKYNVPVYYSVMKDSS 348
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: ENSXETT00000031646.1 (thyrotropin-releasing hormone receptor 3 [Source:NCBI gene;Acc:100489565]) HSP 1 Score: 209.92 bits (533), Expect = 2.042e-63 Identity = 136/339 (40.12%), Postives = 196/339 (57.82%), Query Frame = 1
Query: 151 LMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYL---TTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL------NKKD-------------SKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY---LDCSEMKDPS 1092
+++I +GI GN +VV+VV ++ M TPTNC+LVSL+IAD+I LL++ LP ISE + W + C +LQ+ N SA SIT F+ ER++AIC + AQ +CT++RA KII +W F +Y W +L T +K+ + + C YR++ +Y D IFY+ PL++ +VLY I L N +D + +++ GK S+ +V KML VV+LFA+LW+PYR+ +V NSF + YL++WFVLF R +Y+NSAINPI+YN MS KFR AFK+ C Q + KA +Y + S MKD S
Sbjct: 40 VLLICGVGIAGNIMVVLVVLRTKHMMTPTNCYLVSLAIADLIVLLAAGLPNISEVVAS---WVYGYVGCLCITYLQYLGINISACSITAFTVERYIAICHSIKAQFICTVSRAKKIIAFVWFFTSMYCVMWFFLVDITEVKFADG------VQVNCGYRVSRNLYTPIYFLDFTIFYVIPLVLATVLYGLIARILFMNPLPSNPQDLSRMSSKHYGKPYNSIKLSGKG---NKNTASSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFMDPPYLNVWFVLFCRLCIYLNSAINPIIYNLMSQKFRAAFKNLCKCEQKRTEKAAKYNVPVYYSVMKDSS 366
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: kiaa1324l (KIAA1324-like [Source:Xenbase;Acc:XB-GENE-5954588]) HSP 1 Score: 209.534 bits (532), Expect = 2.968e-63 Identity = 145/373 (38.87%), Postives = 219/373 (58.71%), Query Frame = 1
Query: 52 MNDTSTSDISYPIAQFITVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN------KKDSK-----LRIVGKKFXXXXX------XXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY---LDCSEMKDPS--GNP 1101
M++T+ S+++ + Q ++ Y+++ +++I LGI+GN +VV+VV ++ M TPTNC+LVSL+IAD+I L+++ LP I+E S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT++RA KII +W F LY W +L L Y +++++N C YR+ + +YL D IFY P+ + +VLY I L LN K++SK + K F + + S+ +V KML VV+LFA LW+PYR+ +V NSF + YL WFVLF R +Y+NSAINP++YN MS KFR AF+ C++ S K Y L+ S +K+ S G+P
Sbjct: 1 MDNTTFSELNGTVLQ--KREWHGLEYQVVTVFLVVLICGLGIVGNIMVVLVVLQTKHMRTPTNCYLVSLAIADLIVLVAAGLPNITE--SVYGSWVYGYIGCLCITYLQYLGINASSCSITAFTVERYLAICHPIKAQFLCTISRAKKIIVFVWAFTSLYCLMWFFLLDLN-TTIYKDATVVN--CGYRVPRSFYSPIYLIDFGIFYAVPMTLATVLYGLIARILFLNPIPSDPKENSKTWKNDVTHQNKAFNSKMSSRCSNNTIASRRQVTKMLAVVVILFAFLWMPYRTLVVVNSFLSRPYLQTWFVLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCKCKKKRSEKPANYGVALNYSVIKESSNGGSP 366
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Xenopus
Match: epx (eosinophil peroxidase [Source:Xenbase;Acc:XB-GENE-6039946]) HSP 1 Score: 196.438 bits (498), Expect = 2.417e-58 Identity = 120/302 (39.74%), Postives = 178/302 (58.94%), Query Frame = 1
Query: 190 LVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL-------------------NKKDSKLRIVGKK---FXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTC 1029
+VV+VV+ +R M TPTNC+LVSL++AD++ L+++ LP +S+ S W + C + Q+ NAS+ SIT F+ ER++AIC P+ AQ +CT++RA +II +W+F +Y W +L + ++N S C Y+++ +YL D IFY+TPL+V ++LY I L +K+ ++ G K +K + S+ +V KML VVVLFA+LW+PYR+ ++ NSF +K YLD WF+LF R VY NSAINP++YN MS KFR AFK C
Sbjct: 48 MVVLVVFTTRDMRTPTNCYLVSLAVADLMVLVAAGLPNVSD--SLAGTWIYGHAGCLGITYFQYLGINASSCSITAFTVERYIAICHPMRAQTVCTVSRAKRIIAIVWIFTSIYCMFWFFLVDI-----HVNKS-QQVECGYKVSRNLYLPIYLADFAIFYVTPLLVATILYGLIGRILFLSPIPQHPESTTERWREKSSKEKTESETEGNKPSNRLKTKGALSSRKQVTKMLAVVVVLFALLWMPYRTLVLVNSFMDKPYLDPWFLLFCRICVYANSAINPVIYNLMSQKFRTAFKRLCKC 341
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824]) HSP 1 Score: 209.534 bits (532), Expect = 1.704e-63 Identity = 130/333 (39.04%), Postives = 200/333 (60.06%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN------KKDSK--------------LRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F +Y W +L L +Y N+ +++ C Y+++ Y +YL D +FY+ P+I+ +VLY I L LN K++SK L + F + V S+ +V KML VV+LFA+LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C+Q + KA Y
Sbjct: 24 YQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD--SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNI-STYKNAVVVS--CGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCF---NSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANY 348
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824]) HSP 1 Score: 209.534 bits (532), Expect = 1.704e-63 Identity = 130/333 (39.04%), Postives = 200/333 (60.06%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN------KKDSK--------------LRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F +Y W +L L +Y N+ +++ C Y+++ Y +YL D +FY+ P+I+ +VLY I L LN K++SK L + F + V S+ +V KML VV+LFA+LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C+Q + KA Y
Sbjct: 24 YQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD--SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNI-STYKNAVVVS--CGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCF---NSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANY 348
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824]) HSP 1 Score: 209.534 bits (532), Expect = 1.704e-63 Identity = 130/333 (39.04%), Postives = 200/333 (60.06%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN------KKDSK--------------LRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F +Y W +L L +Y N+ +++ C Y+++ Y +YL D +FY+ P+I+ +VLY I L LN K++SK L + F + V S+ +V KML VV+LFA+LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C+Q + KA Y
Sbjct: 24 YQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD--SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNI-STYKNAVVVS--CGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCF---NSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANY 348
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Trhr2 (thyrotropin releasing hormone receptor 2 [Source:MGI Symbol;Acc:MGI:2177284]) HSP 1 Score: 198.749 bits (504), Expect = 1.681e-59 Identity = 122/320 (38.12%), Postives = 186/320 (58.13%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLN----------KKDSKLRIVG--KKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSK 1050
YK++ + ++++ ++GI+GN +VV+VV SR MHTPTNC+LVSL++AD+I LL++ LP +S+ S + +W + C + Q+ N S+ SI F+ ER++AIC P+ AQ +CT+ RA +II GIW LY W +L L R+ N + C Y+++ +YL D +F+I PL+ T VLY I L ++ S + G + + S+ + +ML +V+LFAVLW PYR+ ++ NSF + +LD W +LF R+ VY NSAINP++Y+ MS KFR AF CR S +
Sbjct: 21 YKVVSVLLVLLVCTVGIVGNAMVVLVVLTSRDMHTPTNCYLVSLALADLIVLLAAGLPNVSD--SLVGHWIYGHAGCLGITYFQYLGINVSSCSILAFTVERYIAICHPMRAQTVCTVARARRIIAGIWGVTSLYCLLWFFLVDLNVRD---NQRL---ECGYKVSRGLYLPIYLLDFAVFFIAPLLGTLVLYGFIGRILFQSPLSQEAWQKERQSHGQSEGTPGNCSRSKSSMSSRKQATRMLAVIVLLFAVLWTPYRTLVLLNSFLARPFLDPWVLLFCRTCVYTNSAINPVIYSLMSQKFRAAFLKLCWCRAAGSQR 332
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Mouse
Match: Hcrtr2 (hypocretin (orexin) receptor 2 [Source:MGI Symbol;Acc:MGI:2680765]) HSP 1 Score: 100.908 bits (250), Expect = 6.042e-23 Identity = 99/372 (26.61%), Postives = 177/372 (47.58%), Query Frame = 1
Query: 52 MNDTST---SDISYPIAQFITVLY----YSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADM---ITLLSSILPV-ISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFN-LLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPE-YLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL--------------------------NKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLP-------YRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTC 1029
+N+T + Y +F+ L+ + Y+ + +++ + +IGN LV + V+ + M T TN F+V+LS+AD+ IT L + L V I+E W F LC + +LQ S + S ++++C + +RW AIC PL + T RA I IW+ + ++ + + N + L VC E Y ++ ++C ++ Y+ PL + + Y+ I L + + SK RI E K ++++ K +ML+ V+++FA+ +LP R + ++ +++ + WF F+ +VY NSA NPI+YN +S KFR+ FK++ +C
Sbjct: 21 LNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET------WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFK--STAKRARNSIVVIWIVSCIIMIPQAIVMECSSMLPGLANKTTLFTVCDEHWGGEVYPKMYHICFFLVTYMAPLCLMILAYLQIFRKLWCRQIPGTSSVVQRKWKQQQPVSQPRGSGQQSKARI--SAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFTHTEDRETVYAWFT-FSHWLVYANSAANPIIYNFLSGKFREEFKAAFSC 381
BLAST of Thyrotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|P21761|TRFR_MOUSE (Thyrotropin-releasing hormone receptor OS=Mus musculus OX=10090 GN=Trhr PE=2 SV=1) HSP 1 Score: 209.534 bits (532), Expect = 1.192e-62 Identity = 130/333 (39.04%), Postives = 200/333 (60.06%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN------KKDSK--------------LRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F +Y W +L L +Y N+ +++ C Y+++ Y +YL D +FY+ P+I+ +VLY I L LN K++SK L + F + V S+ +V KML VV+LFA+LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C+Q + KA Y
Sbjct: 24 YQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD--SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNI-STYKNAVVVS--CGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCF---NSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANY 348
BLAST of Thyrotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|P34981|TRFR_HUMAN (Thyrotropin-releasing hormone receptor OS=Homo sapiens OX=9606 GN=TRHR PE=1 SV=1) HSP 1 Score: 207.223 bits (526), Expect = 1.016e-61 Identity = 129/333 (38.74%), Postives = 195/333 (58.56%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLK---YRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN-------------KKDSKLR----IVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F LY W +L L Y+++ + S C Y+++ Y +YL D +FY+ P+I+ +VLY I L LN K DS + V + V S+ +V KML VV+LFA+LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C+Q + K Y
Sbjct: 24 YQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD--SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVIS------CGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANY 348
BLAST of Thyrotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|O46639|TRFR_BOVIN (Thyrotropin-releasing hormone receptor OS=Bos taurus OX=9913 GN=TRHR PE=3 SV=1) HSP 1 Score: 204.142 bits (518), Expect = 1.531e-60 Identity = 128/333 (38.44%), Postives = 196/333 (58.86%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLK---YRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LN-------------KKDS--KLRIVGKKFXXX--XXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F +Y W +L L Y+++ + S C Y+++ Y +YL D +FY+ P+I+ +VLY I L LN K DS + + + K + V S+ +V KML VV+LFA+LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C+Q K Y
Sbjct: 24 YQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD--SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVVS------CGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSNMWKNDSTHQNKNLNSKTSNRYFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPVEKPANY 348
BLAST of Thyrotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|Q28596|TRFR_SHEEP (Thyrotropin-releasing hormone receptor OS=Ovis aries OX=9940 GN=TRHR PE=2 SV=1) HSP 1 Score: 203.756 bits (517), Expect = 1.976e-60 Identity = 124/333 (37.24%), Postives = 192/333 (57.66%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLK---YRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL----------------NKKDSKLRIVGKKFXXX--XXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F +Y W +L L Y+++ + S C Y+++ Y +YL D +FY+ P+I+ +VLY I L N + + + K + V S+ +V KML VV+LFA+LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C+Q K Y
Sbjct: 24 YQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD--SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVVS------CGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLSPIPSDPKENSNTWKNDSTHQNKNLNSKTSNRYFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPVEKPANY 348
BLAST of Thyrotropin-releasing hormone receptor vs. UniProt/SwissProt
Match: sp|O93603|TRFR_CHICK (Thyrotropin-releasing hormone receptor OS=Gallus gallus OX=9031 GN=TRHR PE=2 SV=1) HSP 1 Score: 201.445 bits (511), Expect = 1.780e-59 Identity = 125/333 (37.54%), Postives = 190/333 (57.06%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLK---YRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL----------------NKKDSKLRIVGKKFXXXX--XXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
Y+++ + +++I LGI+GN +VV+VV ++ M TPTNC+LVSL++AD++ L+++ LP I+E S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CT +RA KII +W F +Y W +L L Y+++ + S C Y+++ Y +Y+ D IFY+ P+++ +VLY I L N + + V K +S + S+ +V KML VVVLFA LW+PYR+ +V NSF + + WF+LF R +Y+NSAINP++YN MS KFR AF+ C K Y
Sbjct: 26 YQVVTILLVLLICGLGIVGNIMVVLVVLRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITE--SLYKSWVYGYVGCLCITYLQYLGINASSFSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWSFASVYCMLWFFLLDLNIAVYKDTTVVS------CGYKVSRSYYSPIYMMDFGIFYVLPMVLATVLYGLIARILFLNPIPSDPKENSNTWKNDMAQQNKTVNSKMTNKSFNSTIASRRQVTKMLAVVVVLFAFLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCHLKRDKKPANY 350
BLAST of Thyrotropin-releasing hormone receptor vs. TrEMBL
Match: A0A430QN94 (Thyrotropin-releasing hormone receptor OS=Schistosoma bovis OX=6184 GN=DC041_0009753 PE=3 SV=1) HSP 1 Score: 268.855 bits (686), Expect = 1.110e-83 Identity = 142/340 (41.76%), Postives = 214/340 (62.94%), Query Frame = 1
Query: 100 ITVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGK---------------------------KFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQI 1038
I +++YS YK++GTI+L VIL++G+IGN V++V+ S +HTPTNC+L+SLS +D++ L++S ++ E++ N+WR C ++V LQ+ S +ASA+SI FS ERW+ IC P+ A MCT+ RA+KII GIW+F L YN W++++T + S S CT++ + +Y+CDLI+FY+ PL++TSV+Y I L + + +VG+ K K V+++ +V+K+L+ +VVLFA WLPYRS +VYNSF+ Y DLWF +F+R M ++NSA+NPILYNAMS KFR+A K L C ++
Sbjct: 18 IPLIHYSLPYKLVGTISLSVILTVGVIGNIFVMLVLILSSKLHTPTNCYLISLSASDLLVLMTSTTLMVQEFYQPYNHWRLGNFACQLSVCLQYLSVDASALSICAFSVERWVGICYPMRAHYMCTIKRAIKIITGIWIFTLTYNIPWIFMSTTVKQYSEYGSF---ETCTFKFKRTAYKAIYMCDLIVFYVLPLLITSVMYCQISWRLFRTDNKGISLVGQHINFNQIISSSKTERSYATISETQHNLKLRKVINRVRARRQVVKLLMIIVVLFASFWLPYRSMVVYNSFSLHGYHDLWFRMFSRIMAFLNSAVNPILYNAMSRKFRRALKRLLKCHKV 354
BLAST of Thyrotropin-releasing hormone receptor vs. TrEMBL
Match: V4A7L7 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_122499 PE=3 SV=1) HSP 1 Score: 268.855 bits (686), Expect = 2.210e-83 Identity = 147/330 (44.55%), Postives = 210/330 (63.64%), Query Frame = 1
Query: 112 YYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL------LNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXX-------------TVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTC-RQIF 1041
+YS +++I +I +G+IGN LVVIV+ +R MHTPTNC+L+SL++AD++ LLS+ LP I E +++ WRF LC + +FLQ+ +AS+ SIT F+ ER+ AICKP+ AQ MCT+ RA KII GIW+ +Y S WL LT L+ R + I+ C +RL+ ++ DL+IFY+ P I+++VLY I L +++ D++ I K+ + V ++ + I VV++FA LW+PYR +VYNSFA KY+DLWF+LF+RSMVY+NSAINPILYNAMS KFR+AF++ L C R IF
Sbjct: 42 HYSTSFQLIAATISAIIFIVGLIGNVLVVIVIARTRSMHTPTNCYLLSLAVADILVLLSATLPAIPEPFFQIDEWRFGRVLCSLLIFLQYLGVDASSASITAFTVERYFAICKPMRAQTMCTVNRAKKIIVGIWILTTIYCSPWLGLTDLR-RVQQTDGHIIEK-CDFRLSRSSYLAYFMTDLVIFYVIPFIISAVLYCLIGRILFSDSLNISRGDNRSDIHAKRHSQARVQVSYSERLTIITIPFFPLFQVVRMLFVVVLVFATLWMPYRVIVVYNSFATNKYMDLWFLLFSRSMVYINSAINPILYNAMSVKFRRAFRNHLCCGRYIF 369
BLAST of Thyrotropin-releasing hormone receptor vs. TrEMBL
Match: A0A3Q0KMD9 (Putative thyrotropin-releasing hormone receptor OS=Schistosoma mansoni OX=6183 PE=3 SV=1) HSP 1 Score: 267.7 bits (683), Expect = 3.106e-83 Identity = 141/340 (41.47%), Postives = 212/340 (62.35%), Query Frame = 1
Query: 100 ITVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGK---------------------------KFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQI 1038
I ++ YS YK++GTI+L VIL++G+IGN V++V+ S +HTPTNC+L+SLS +D++ L++S ++ E++ N+WR C ++V LQ+ S +ASA+SI FS ERW+ IC P+ A MCT+ RA+KII GIW+F L YN W++++T + S S CT++ + +Y+CDLI+FY+ PL++TSV+Y I L + + +VG+ K K +++ +V+K+L+ +VVLFA WLPYRS +VYNSF+ Y DLWF +F+R M ++NSA+NPILYNAMS KFR+A K L C ++
Sbjct: 17 IPLILYSLPYKLVGTISLSVILTVGVIGNIFVMLVLTLSSKLHTPTNCYLISLSASDLLVLMTSTTLMVQEFYQPYNHWRLGNFACQLSVCLQYLSVDASALSICAFSVERWVGICYPMRAHYMCTIKRAIKIITGIWIFTLTYNIPWIFMSTTVKQYSEYGSF---ETCTFKFKRTAYKAIYMCDLIVFYVLPLLITSVMYCQISWRLFRTDNKGISLVGQQINFNQIISSGKTERSYATISETQHNLKLRKVINRARARRQVVKLLMIIVVLFASFWLPYRSMVVYNSFSLHGYHDLWFRMFSRIMAFLNSAVNPILYNAMSRKFRRALKRLLKCHKV 353
BLAST of Thyrotropin-releasing hormone receptor vs. TrEMBL
Match: A0A4Z2DSE9 (Thyrotropin-releasing hormone receptor OS=Schistosoma japonicum OX=6182 GN=EWB00_009085 PE=3 SV=1) HSP 1 Score: 264.233 bits (674), Expect = 7.286e-82 Identity = 142/340 (41.76%), Postives = 214/340 (62.94%), Query Frame = 1
Query: 100 ITVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGK---------------------------KFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQI 1038
I ++YYS YK++GTI+L +IL++G+IGN LV++V+ + +HTPTNC+LVSLS +D++ L++S ++ E++ N+W C ++V LQ+ S +ASA+SI FS ERW+ IC P+ A MCT+ RA+KII GIW+F L YN W++++T + S S CT++ + +Y+CDL+IFY+ PL +TSV+Y I L + + +VGK K K V+++ +V+K+L+ +V+LFA WLPYRS +VYNSF+ Y DLWF +F+R M ++NSA+NPILYNAMS KFR+A K L C+++
Sbjct: 17 IPLIYYSLSYKLLGTISLTIILTVGVIGNILVMLVLTLTTKLHTPTNCYLVSLSASDLLVLMTSTTLMLQEFYQPYNHWILGNFTCQLSVCLQYLSVDASALSICAFSVERWVGICYPMRAHYMCTIKRAIKIITGIWIFTLTYNIPWIFMSTTVIQYSEYGSFY---TCTFKFKRTAYKAIYMCDLLIFYVLPLFITSVMYCQISWRLFRTDNKGISLVGKHINFNQTISPDKKDRSYAIINESQQNLKLRKVISRVRARRQVVKLLMIIVILFASFWLPYRSMVVYNSFSLYGYHDLWFRMFSRIMAFLNSAVNPILYNAMSRKFRRALKRLLKCQKV 353
BLAST of Thyrotropin-releasing hormone receptor vs. TrEMBL
Match: A0A210QN11 (Thyrotropin-releasing hormone receptor OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT14081 PE=3 SV=1) HSP 1 Score: 263.462 bits (672), Expect = 2.453e-80 Identity = 151/352 (42.90%), Postives = 225/352 (63.92%), Query Frame = 1
Query: 31 ITTFPQ-TMNDTSTSDISYPIAQFI-TVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKK--DSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEYLDCS 1074
IT P+ +N+T+ D + + YS +YK+I I ++I +G++GN LV++VV R M TPTNC+L+SLS+AD + LLS+ LP I E + N+W + +C + VF+Q+ A+ASA+SIT F+ ER++AIC P+ AQ +CT RA +II +W F++LY + WL LTT+ Y + S+ L+ CTYRL E Y+ D IFY+ PL+++ +LY I+ L NK DS + + + S+ +VI+ML+ +VV+FA+LWLPYR+ +VYNS A+ KYL++WF LF R MVY+NSA+NPILY+ MS KFRKA+ L+C F ++ ++ S
Sbjct: 22 ITQEPEFVINETNEGDSKSCLPTVVMGSDDYSPLYKVIAVIVPLIIFMIGMLGNLLVIVVVSRRRSMQTPTNCYLISLSVADCLLLLSATLPSIPEPLFRRNHWPWGRAMCSVLVFVQYLGADASALSITAFTLERYIAICHPMKAQTICTARRAKRIIISLWCFSVLYCTPWLGLTTMTYNLTCDGSAPLHS-CTYRLERESYLFYYMTDFFIFYVFPLLLSGILYSFIIRILFNKSALDSDGSKAPEYSSRTRQTSNSRCQVIRMLVVIVVVFAMLWLPYRAIVVYNSLADYKYLNVWFWLFCRIMVYINSAVNPILYSLMSLKFRKAYHRILSCNPHFKRQSSGTINES 372
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: trhrb (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103029490]) HSP 1 Score: 219.935 bits (559), Expect = 1.026e-67 Identity = 131/327 (40.06%), Postives = 194/327 (59.33%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL----------NKKDS-----KLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
YK+I T+ ++ I +LGI+GN +V++VV ++ M TPTNC+LVSL+ AD++ L+++ LP +++ S W F C + Q+ NAS+ SIT F+ ER++AIC P+ AQ +CT TRA +II G+WV LY W YL ++ Y +++I++ C Y+++ +Y D +F++ PL +++VLY I L N D K + S S+ +V KML VV+LFAVLW+PYR+ +V NSF ++ YLD WF+LF R+ VY+NSAINP++YNAMS KFR AFK C +K Y
Sbjct: 21 YKLISTLIVLTICALGIVGNVMVILVVLTTKHMRTPTNCYLVSLAAADLMVLVAAGLPSVAD--SLYGSWLFGRVGCLCITYFQYLGINASSCSITAFTVERYIAICHPIRAQSLCTYTRAKRIILGVWVTTSLYCVMWFYLADIE-ELVYEDATIVS--CAYKVSRNLYLPIYFFDFGVFFVLPLTLSTVLYGLIARILFLNPLPKTKSKNGHDGVYSGNKTNGLKSSSQCSSTTAASRRQVTKMLAVVVILFAVLWMPYRTLVVVNSFLQEAYLDTWFLLFCRTCVYLNSAINPVIYNAMSQKFRAAFKRLCRCGPRVQAKQAAY 342
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: TRHR (thyrotropin-releasing hormone receptor [Source:NCBI gene;Acc:103040459]) HSP 1 Score: 215.312 bits (547), Expect = 1.029e-65 Identity = 132/333 (39.64%), Postives = 196/333 (58.86%), Query Frame = 1
Query: 115 YSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL-------NKKDSKL----------RIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
+S YK + ++ + LGIIGN +V++VV ++ M TPTNC+LVSL++AD++ L ++ LP I++ S W + C +LQ+ NAS+ SIT F+ ER++AIC P+ AQ +CTL+RA KII +W F LY W L L+ ++++ N++++ +C Y+++ +Y D +FY+ PL++ +VLY I L+ K++SK K S S+ +V KML VV+LFA+LW+PYR+ +V NSF EK YLD WFVLF R +Y+NSAINP++YNAMS KFR AF+ C K Y
Sbjct: 25 HSVEYKAASVLLVLFVCGLGIIGNAMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPNITD--SLFEQWVYGYAGCLSITYLQYVGINASSCSITAFTVERYIAICHPIRAQSLCTLSRAKKIIALVWTFTGLYCVMWFCLADLE-QQTHGNTTVV--ICAYKVSRTQYLPIYFTDFALFYVLPLLLATVLYGLIARILILNPLPSDPKENSKAWRKSTNTSSSTQRAAKSSSYSTTATSRRQVTKMLAVVVILFALLWMPYRTLVVVNSFLEKPYLDTWFVLFCRICIYLNSAINPVIYNAMSQKFRAAFRKLCHCGPQHLEKPPAY 352
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: trhr2 (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103031192]) HSP 1 Score: 215.698 bits (548), Expect = 1.286e-64 Identity = 132/344 (38.37%), Postives = 195/344 (56.69%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDI-------------------VLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTC-RQIFSSKAQEYLD---CSEMKDP 1089
YK + ++++ +GI+GN +VV+VV +R M TPTNC+LVSL++AD+ L+++ LP ISE S M W + C +LQ+ N S+ SIT F+ ER++AIC P+ AQ +CT++RA +II G+W F +Y WL+L ++ +NS C YR++ + +YL D IFY+ PL++ LY I TL + V + + + S+ +V KML VV+LFA+LW+PYR+ ++ NSF K YLD WF+LF R+ +Y NSAINP++YN MS KFR AF+ C RQ + L+ CS +DP
Sbjct: 32 YKTVSVFLVLLVCGVGIVGNIMVVLVVLTTRHMRTPTNCYLVSLAVADLTVLVAAGLPNISE--SLMATWVYGHAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMRAQTVCTVSRAKRIIAGVWAFTCVYCMLWLFLVDIQ-----VNSD-GRVQCGYRVSRDLYLPIYLIDFAIFYVIPLLLAIALYGLIARILYLSPLPHPPDSGTVTATTLRRSCKEPVDAVKGRQGRPKSALSSRKQVTKMLAVVVILFALLWMPYRTLVLINSFVSKPYLDAWFLLFCRTCIYANSAINPVVYNLMSQKFRSAFRGLYRCQRQAGHHRTLSTLNTAACSMARDP 367
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: ENSAMXT00000054912.1 (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103035526]) HSP 1 Score: 205.682 bits (522), Expect = 4.749e-62 Identity = 131/308 (42.53%), Postives = 180/308 (58.44%), Query Frame = 1
Query: 154 MVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LNKKDSKLRIVGKKFXXXX--------------XXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCR 1032
++I +GI GN +VV+VV ++ M TPTNC+LVSL+IAD+I LL++ LP ISE + W + C +LQ+ N S+ SIT F+ ER++AIC + AQ +CT++RA KII +W+F LY W +L + Y N I+ C YR++ VY D +FY+ PLIV +VLY I L +N S L G + + V S+ +V KML VVVLFA+LW+PYR+ +V NS + YL+ WF+LF R +Y NSAINPI+YNAMS KFR AFK C+
Sbjct: 37 LLICGVGIAGNVMVVLVVLRTKHMMTPTNCYLVSLAIADLIVLLAAGLPNISEVVAS---WIYGYAGCLCITYLQYLGINVSSCSITAFTVERYIAICHSIKAQFICTVSRAKKIIACVWIFTSLYCIMWFFLVD-THEMVYANGVIVR--CGYRVSRNLYMPVYFLDFTLFYVIPLIVATVLYGLIARILFMNPLPSNLSERGSDSIHQGRTNSTVKVSCKPNKGAVSSRKQVTKMLAVVVVLFALLWMPYRTLVVVNSLMDPPYLNTWFLLFCRMSIYTNSAINPIIYNAMSQKFRTAFKKLCHCK 338
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Cavefish
Match: nmur3 (neuromedin-U receptor 2-like [Source:NCBI gene;Acc:103035443]) HSP 1 Score: 117.087 bits (292), Expect = 9.709e-29 Identity = 93/346 (26.88%), Postives = 166/346 (47.98%), Query Frame = 1
Query: 142 TINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNY-WRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYL-RIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXT-----VVVLFAVLWLPYRS----WIVYNSFAEKKYLDLWFV-LFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIF----SSKAQEYLDCSEMKDPSG----NPYLAVCH 1119
T+ ++I G++GN L IV+ R M TPTN +L SL+++D++ LL + + Y NY + F +C VFL AS +++T S ER++A+ PL + T A K+I G+W+ +L+ L + Y Y+ +L L P+++ +V ++FY P++V LY+ I + L ++ + R +G+ + + +T VV++FA+ W P+ + W + ++ Y +V + + + Y++SA+NPI+YN +S++FR+ F + R +S Y S KDP+ NP + H
Sbjct: 60 TLTYILIFITGVLGNLLTCIVIIKHRKMRTPTNLYLFSLAVSDLLVLLFGM--PLEIYELWQNYPFPFGESVCCFKVFLFETVCFASVLNVTVLSVERYVAVVHPLKTRYALTNKHAQKMIGGVWIVSLVCAVPNTSLHGIHY--YYLPEKVLESATCNLLKPQWIYNLVIQVTTVLFYFVPMMVICGLYLVIGMKLGREQKQQGRKLGRNCSADVSRRVQVESGRRRQVTKMLAVVVLVFAICWAPFHTDRLLWSFITQWTDRMYSVFEYVHILSGVLFYLSSAVNPIIYNLLSSRFRERFLELMCARGDGNTSRNSSPPSYKRTSYPKDPTAPAQTNPPITAAH 401
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: trhrb (thyrotropin-releasing hormone receptor b [Source:ZFIN;Acc:ZDB-GENE-060503-382]) HSP 1 Score: 187.193 bits (474), Expect = 3.166e-56 Identity = 120/330 (36.36%), Postives = 175/330 (53.03%), Query Frame = 1
Query: 112 YYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNP-----VCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXX-------------------XXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTC 1029
+Y+ Y+ + ++ I GI+GN ++V+VV ++ M TPTN +L SL+IAD++ LL++ LP +S+ S W + C +LQ+ N S+ SIT F+ ER++AIC P+ AQ +CT++RA +I+ +W +Y W +L + R S +P C YR++ +Y D FY+ PL++ VLY I LL R + V S + + +V KML VV+LFAVLWLPYR +V NSF Y D WF+LF R +Y NSAINP++YNAMS KFR AF+ C
Sbjct: 26 HYTATYRAVSLALVLAICGAGIVGNVMIVLVVVRTKHMRTPTNYYLGSLAIADLLVLLAAGLPNVSD--SLAESWVYGYAGCLAITYLQYLGINVSSCSITAFTLERYLAICHPIRAQSLCTVSRAKRILALVWSSTAIYCLVWFFLVDVHPR-SQGGGGGEDPRSNVTECGYRVSRNLYLPIYFFDFAAFYVLPLVLACVLYALIARVLLLPPPPASRTLAAPAVPLSLPLAAVCSGAVPSVNRRGKSAYSSRKQVTKMLAVVVLLFAVLWLPYRMLVVVNSFVSSPYHDAWFLLFCRLCLYANSAINPVVYNAMSQKFRAAFRKLCGC 352
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: qrfpr4 (pyroglutamylated RFamide peptide receptor 4 [Source:ZFIN;Acc:ZDB-GENE-091204-354]) HSP 1 Score: 91.2781 bits (225), Expect = 8.407e-21 Identity = 82/312 (26.28%), Postives = 155/312 (49.68%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIAD-MITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCD-LIIFYITPLIVTSVLYIDIVLTLLNK---KDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYV------NSAINPILYNAMSAKFRKAFKSSLTC 1029
+ ++G + + +L + GN LV+ VV + +HT N F+ SL+++D MIT+ + ++ + S W LC + F+Q + S +++ C + ER+ I PL ++ T RA ++ G+W+ L + Y T++ + + + C+ + + R Y L++ ++ PL+ + LY + L K D+ + + + +KI +SK + +KM++ VV+LFAV W P+ V NS K L++ F + A ++ V NS NPI+Y A++ ++K +L+C
Sbjct: 48 FAVVGAL----VFTLALSGNALVIFVVARRKALHTVANVFVCSLAVSDLMITVFCIPITLMQNFFSN---WIAGVALCKLVPFIQVTAVTTSMLTMACIAVERFQGILHPLRSRSRYTTARAASMLCGVWLVGLCVAAPMFYAHTVQVTYDVL-YDVSHTGCSEQWSHAEHRQAYTTTLLLVTFVLPLLTMTALYTRLAHELWVKTRVHDAVFNALQRS--EINKITRSKKRAVKMMVIVVILFAVCWAPFH---VVNSLVPKGNLEMSFDMEAITLAMVQLFGFSNSLWNPIVYAALNQNYKKQLAIALSC 346
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: nmur1a (neuromedin U receptor 1a [Source:ZFIN;Acc:ZDB-GENE-081104-220]) HSP 1 Score: 87.8113 bits (216), Expect = 1.508e-19 Identity = 87/348 (25.00%), Postives = 157/348 (45.11%), Query Frame = 1
Query: 55 NDTSTSDISYPI------AQFITVL---YYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWR-FAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYL-RIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXT-----VVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMV-----YVNSAINPILYNAMSAKFRKAFKSSLTCRQ 1035
+D TS+ S P+ Q IT L S + + I L++ ++ G++GNFL IV+ R M TPTN +L SL+++D++ L+ + + Y NY F C L AS +++T S ER++A+ PL A+ + T T A ++I +WV ++ + L + Y S + P ++ +V + F++ P+ SVLY+ I L +K + + + +T +V++F + W P+ + + SF + D + +V Y++S +NP++YN +S +FR F+ + CR+
Sbjct: 20 DDNETSNYSLPVEFYMTRGQVITELLGPRTSPFFVPVLAIYLLIFVT-GVVGNFLTCIVISRHRLMRTPTNFYLFSLAVSDLLVLVLGM--PLELYEMWENYPSLFGEGGCYFKTMLFETVCFASVLNVTALSVERYIAVVHPLKARWLVTRTHARRVIACLWVASVCCSVPNTSLHGIHYIRSPLGEPYEESTICIVTQPRWIYNVVVQLTALFFFLVPMATISVLYLLIGRQLRREKSLAVPHECEGRGTFGNQRIRTNRSKCRQVTKMLYVLVIVFGICWAPFHTDRLVWSFVHRWTADSHGMFQCVHLVSGVFFYLSSVVNPVIYNLLSTRFRDMFREVM-CRR 363
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37]) HSP 1 Score: 80.8777 bits (198), Expect = 3.038e-17 Identity = 80/305 (26.23%), Postives = 141/305 (46.23%), Query Frame = 1
Query: 154 MVILSLGIIGNFLVVIVVYFS--RGM-HTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWL-YLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLY----------IDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAE--KKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSS 1020
++I LG GN LV+IV+ S RG +T TN F+++LS+AD+ +L + P + ++ ++ W F LC F+ F + AS+ ++ S +R++AI PL ++ + T +A +I IW L++ +L Y + ++ N S+ PV + ++C Y+ P+ V + Y +D + + K +K ++ M++ V LF WLP+ I+Y F + F L + M Y NS +NP++Y +S FRK F+ +
Sbjct: 33 LLIFLLGAFGNSLVIIVLLCSGQRGSSNTTTNIFILNLSVADLCFILFCV-PFQATIYT-LDGWIFGSFLCKAVHFIIFLTMFASSFTLAAVSVDRYLAIRYPLRSRELRTPRKAAAVIAAIWGLALVFAGPYLSYYQAVTFQ----NMSMCMPVWAKEPRKLMDMVTFVCG----YLVPVSVLGLAYAFTLKYLWTAVDPLEEMSESKRAKRKVT------------------TMILIVAGLFCACWLPHHVLILYFWFGHFPLTHATYAFRLLSHCMSYANSCLNPLVYALVSKHFRKGFRKA 309
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Match: npy8br (neuropeptide Y receptor Y8b [Source:ZFIN;Acc:ZDB-GENE-980526-208]) HSP 1 Score: 78.5666 bits (192), Expect = 2.166e-16 Identity = 83/304 (27.30%), Postives = 139/304 (45.72%), Query Frame = 1
Query: 157 VILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNP------VCTYRLNPEYLRIVYLCDLIIFYIT-PLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYL----DLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQ 1035
V+++LG++GN L+V+V+ +H TN +V+L+ +DM+ L LP+ Y + M++W F LC + FLQ + + S S+ + ER I P + +L A I IWV +S +L L E Y N S P C + + + L++F + PL+ + Y+ I L L +K K+ G++ K+ ML+ +V FA+ WLP ++ + + L DL F L ++ INPI Y ++ F+K K+++ C Q
Sbjct: 47 VLIALGLLGNSLLVLVILRHSELHNVTNILIVNLAFSDMLVGLVC-LPLTIAY-TLMDHWIFGEALCKGSPFLQCSAVSVSIFSLVLIAIERHQLIINPTGWKP--SLNHAYVAIGAIWVTAFAMSSPFLAFHVLT-DEPYRNLSHYFPDYGEKVACIELWPSDTSKFAFTTSLLVFQFSCPLLFVFLCYLRIFLRLRQRK--KMLPTGREGGGNGVRASHMKKINMMLVAIVAGFAICWLPLYAFNAVSDWNPTLLLHCQHDLIFSL-CHLTAMLSICINPIFYGFLNNNFQKELKATILCCQ 342
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO40944 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5Q4]) HSP 1 Score: 88.1965 bits (217), Expect = 6.802e-20 Identity = 86/298 (28.86%), Postives = 141/298 (47.32%), Query Frame = 1
Query: 154 MVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSI---LPVISEYHSKMNY-WRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIF-YITPLIVTSVLYIDIVLTLLNK----KDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLW-FVLFARSMVYVNSAINPILYNAMSAKFRKAFKS 1017
++I + +GN LV IV+ R M T TN F+++L+IAD+ I +PV +MNY W + +C I LQ S AS ++T S R+ AI PL Q+ +++ + +II IWV +++ S + Y+ L + + ++ C +R VY L +F Y+ PL V + YI I + L + + LR V + ++ + + V+ + + LWL + AE++Y W V F + + NSA NPI Y ++ +RK FKS
Sbjct: 1 VIIFLISAVGNSLVCIVILRRRRMKTVTNYFVLNLAIADLALTCICIPFDIPV-----QEMNYVWPYGGFMCKILYPLQTLSLFASVFTLTAVSLTRYWAIVHPLRQQL--SVSNSKRIIVAIWVISIIPVSPYSYV--LSHEDGSLS-------CEENWGDTSMRKVYTAVLFMFQYVLPLTVIAGAYIGIGIELRKRQTRDRSGGLRDVHAEETRKVLRMLKVVTVVFAVFVLPTNIMWLWLDF-------GHAEQEYDRFWDLVAFCNIVTFANSAANPICYTVLNETYRKEFKS 275
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO39716 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S996]) HSP 1 Score: 83.1889 bits (204), Expect = 3.721e-18 Identity = 83/296 (28.04%), Postives = 142/296 (47.97%), Query Frame = 1
Query: 157 VILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRL--NPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL---LNKKDS--KLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYR---SWIVYNSFAEKKYLDLWFVL-FARSMVYVNSAINPILYNAMSAKFRKAF 1011
VI SL ++GN V+++V +R +H+ T + +LSIAD+ L I P Y +++ YW F +C + Q + AS +++ SF+R+ +I P A++ ++++ II +WV + + L + + + P+C +P Y RI I+ Y PL + + Y +V L +K D R+ K KV++MLI VV + V +LPY W+ + ++ ++ W +L ++ +VY NS INPILY S +FR+ F
Sbjct: 9 VIFSLTVLGNIFVIVLVIKTRELHSVTGYLICNLSIADLCVGLLCI-PFTLTY-AELKYWPFGRVMCKTILPAQAMAVMASVATLSAISFDRFRSIAYPYEARI--SVSKVKFIIASVWVM-----AGVMGLPLVAVLDVRLFPGFGKPICDEYGWPSPLYRRIYSTATFIVTYAVPLPLMATWYAIVVYKLEQAAHKGDDSEGFRVAQAK-----------GKVVRMLIVVVAAYFVCFLPYHVSMMWLEFGDVSQSRF--FWILLSYSHVLVYANSCINPILYCIFSEQFRRGF 282
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO33974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQR4]) HSP 1 Score: 81.2629 bits (199), Expect = 1.829e-17 Identity = 88/292 (30.14%), Postives = 138/292 (47.26%), Query Frame = 1
Query: 154 MVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNK-KDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWF----VLFARSMVYVNSAINPILYNAMSAKFRKAFK 1014
++I +G+IGN LV +VV R M TN F+V+L+ AD+ LL I E + NYW + +C + LQ + AS ++ S R+MAI PL Q+ T T A K+I +WV +L S Y+ L+ R + T+ + ++ Y+ PL + + Y D +L LR +K +K KV+K+L VV+ FA+L LP ++ F D + V + +VY NSA NP++YNA++ +FR+ F+
Sbjct: 2 VLIFIIGVIGNILVCLVVCRQRKMKNVTNYFIVNLAAADLAVLLICIPFDFGEIIT--NYWPYGSIMCKLVYPLQTMATTASVGTLVAISLNRFMAIVYPLRPQL--TTTDAKKVITVVWVLSLALVSP--YIAVLRMRGQHCQE-------TFEERGMQAGAYTMAIFLLQYVLPLTLIGLSYTDPGTHILAHYMRRSLRGHQQK------ALKKAHKVVKVLTGVVITFALLMLPNHVVFIWIDFGRGGGCDHEYVNQIVSLGQILVYFNSATNPLIYNAVNEQFREGFR 274
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO46500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ52]) HSP 1 Score: 82.0333 bits (201), Expect = 2.116e-17 Identity = 85/335 (25.37%), Postives = 156/335 (46.57%), Query Frame = 1
Query: 136 IGTINLM------VILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITV----FLQFCSANA--------SAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYL----DLWFVLFA--RSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEYLD 1068
IGTI+++ +I +G+ GN LV++VV +R MHT TN LV+L+ AD+ TLL+ + YW P+ + +F + NA S++++T + ER+ A+ KP+ + ++ ++ IW ++L N KY E Y + P + PE+ + LC ++ + P ++ S YI IV L K + G +++K ++ ++LI+V F V ++ Y + Y F +++ + +L +++ + +S INPILY S+ +R+ FK C ++ Q ++D
Sbjct: 24 IGTIDIVFAVLYFLIDIIGVTGNALVILVVKRNRSMHTTTNFLLVNLAFADIFTLLTC---------PRNGYWLAVTASHPVGLAGDYICKFFTGNALVGITASVSSLTLTVLAVERYRALLKPMERKYSVSMENVKFVMTAIWGISILVNIPDFLKN--KYSEHY--GKCVCPFSLELVQPEFTHV--LCTVLFLGVAPSLILSFCYIQIVSGLFLTKKICSEVTGN-----LNEIEAKKRLARLLISVTFAFYVCYISYGVYFSYLLFQDREKIIQKYNLHYIILKTVEFTLVCSSCINPILYGFQSSNYREGFKKLCFCH----ARRQGHVD 334
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Nematostella
Match: EDO45537 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSB3]) HSP 1 Score: 80.8777 bits (198), Expect = 2.485e-17 Identity = 76/297 (25.59%), Postives = 147/297 (49.49%), Query Frame = 1
Query: 163 LSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTR-AVKIIFGIWVFNLLYNSSWLYLTTLKY--RESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMV--YVNSAINPILYNAMSAKFRKAFKSSLTCRQI 1038
LS G++GN LV +VVY + MHT N FLV+L++ D+ + +I + + + ++ YW F C + LQ + +AS S+ + ER+ AIC P++ + T + A+ + + + F L Y T +Y E + P+ PE +I + I Y+ PL++ YI ++L L ++ ++ + ++ + +K + V+KM+ VV+ + V +PY + +++ + +++L + + + NS +NP++Y S +F K F L C ++
Sbjct: 4 LSTGVVGNILVCVVVYKNHRMHTAMNMFLVNLAVCDIFVCVFNI--IFTLIYFQLQYWPFGLVWCKMLPTLQITNISASTGSLVAMTVERYRAICMPMSNPISRTHAKLAIALAWMVGFFVALPEVG-AYTLTGEYGCGEQW-------PI------PELQKIYSMFLFIAIYVVPLLMLLPAYIRMILKLWIVQE-EVTVASSGISQDPQSIKRRRNVLKMMAIVVLSYGVCLMPYHAAFIWHDYGTGIITPWFWILLCYTQIISWFNSCVNPVIYWFFSEQFSKEFNKILGCNKL 283
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Medaka
Match: trhr1b (TRHR1b protein [Source:NCBI gene;Acc:100533509]) HSP 1 Score: 221.09 bits (562), Expect = 5.758e-68 Identity = 131/328 (39.94%), Postives = 191/328 (58.23%), Query Frame = 1
Query: 115 YSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTL-LNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXT-----------VVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY 1062
YS YK I ++ L VI + GI+GN +V++VV ++ M TPTNC+LVSL++AD++ L ++ LP I++ S W F C + Q+ NAS+ SIT F+ ER++AIC P+ AQ +CTL+RA KII +W F +Y W YL+ ++ Y N +I+ C YR+ ++ VY D +F++ PL++++VLY I L LN S+ + K K + T VV+LFAVLW+PYR+ +V NSF ++ YLD WF+LF R +Y+NSAINP++YNAMS KFR AF+ C S K +
Sbjct: 20 YSMQYKAISSLLLFVICASGIVGNIMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPAITD--SIFATWVFGRYGCLCITYFQYLGINASSCSITAFTIERYIAICHPIKAQFLCTLSRAKKIILFVWAFTSIYCVMWFYLSDIQ-ELVYENITIIT--CGYRVPRKFYLPVYFFDFGVFFVLPLLLSAVLYGLIARILFLNPLPSEHKAKKKSGANNPKTSCKNSRHSSSTATSRRQVTKMLAVVVILFAVLWMPYRTLVVVNSFLDQAYLDSWFLLFCRICIYLNSAINPVIYNAMSQKFRAAFQKICHCGMKGSDKPAAH 342
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Medaka
Match: trhr2 (TRHR2 protein [Source:NCBI gene;Acc:100533510]) HSP 1 Score: 219.164 bits (557), Expect = 8.036e-68 Identity = 124/329 (37.69%), Postives = 195/329 (59.27%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYR-ESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYI---------------DIVLTLLNK--KDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQE 1059
YK + ++++ +GIIGN +VV+VV+ +R M TPTNC+LVSL+IAD+ L+++ LP +S+ S W F C +LQ+ N S+ SIT F+ ER++AIC P+ AQ +CT++RA +II G+W+F +Y WL+L ++ + ++ C YR+ E +YL D IFY+ PL++ VLY D T L + +D+ + + + S+ +V KML VV+LFA+LW+PYR+ ++ NSF YL+ WF+LF R+ +Y NSAINP++YNAMS KFR AF+ +C+++ ++ +
Sbjct: 21 YKTVSVFLVLLVCGVGIIGNVMVVLVVFTTRHMRTPTNCYLVSLAIADLTVLVAAGLPNVSD--SLTGTWIFGQAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMKAQTVCTVSRAKRIIAGVWIFTCVYCMLWLFLVDIQVGPDGHVQ-------CGYRVKRELYLPIYLIDFAIFYVIPLLLAIVLYALIARILYLSPLPHQPDTSATTLRRSCRDTSEAARPGRQGRPKSALSSRKQVTKMLAVVVILFALLWMPYRTLVLINSFVSTPYLNAWFLLFCRTCIYANSAINPVIYNAMSQKFRLAFRGLYSCQRLEGNQRTQ 340
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Medaka
Match: trhr2 (TRHR2 protein [Source:NCBI gene;Acc:100533510]) HSP 1 Score: 218.779 bits (556), Expect = 1.791e-66 Identity = 124/329 (37.69%), Postives = 195/329 (59.27%), Query Frame = 1
Query: 127 YKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYR-ESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYI---------------DIVLTLLNK--KDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQE 1059
YK + ++++ +GIIGN +VV+VV+ +R M TPTNC+LVSL+IAD+ L+++ LP +S+ S W F C +LQ+ N S+ SIT F+ ER++AIC P+ AQ +CT++RA +II G+W+F +Y WL+L ++ + ++ C YR+ E +YL D IFY+ PL++ VLY D T L + +D+ + + + S+ +V KML VV+LFA+LW+PYR+ ++ NSF YL+ WF+LF R+ +Y NSAINP++YNAMS KFR AF+ +C+++ ++ +
Sbjct: 29 YKTVSVFLVLLVCGVGIIGNVMVVLVVFTTRHMRTPTNCYLVSLAIADLTVLVAAGLPNVSD--SLTGTWIFGQAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMKAQTVCTVSRAKRIIAGVWIFTCVYCMLWLFLVDIQVGPDGHVQ-------CGYRVKRELYLPIYLIDFAIFYVIPLLLAIVLYALIARILYLSPLPHQPDTSATTLRRSCRDTSEAARPGRQGRPKSALSSRKQVTKMLAVVVILFALLWMPYRTLVLINSFVSTPYLNAWFLLFCRTCIYANSAINPVIYNAMSQKFRLAFRGLYSCQRLEGNQRTQ 348
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Medaka
Match: trhr (thyrotropin releasing hormone receptor [Source:NCBI gene;Acc:100533508]) HSP 1 Score: 204.527 bits (519), Expect = 3.377e-62 Identity = 138/338 (40.83%), Postives = 199/338 (58.88%), Query Frame = 1
Query: 115 YSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLL------NKKDSKLRIVGK-KFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEY---LDCSEMKDPSGN 1098
YS YK+I + + +I +GI+GN +V++VV ++ M TPTNC+LVSL+ AD++ L ++ LP I++ + W + C + Q+ NAS+ SIT F+ ER++AIC P+ AQ +CTL+RA KII +W +Y WL+L+ K + Y N +L C Y+++ + +Y D +FY+ PL++ +VLY I L + K S R G + + S+ + + V KML VVVLFAVLW+PYR+ +V NSF EK YLD WF+LF R +Y+NSAINP++YNAMS KFR AFK C K Y L S +KD S
Sbjct: 21 YSIEYKVISVLLVSLICGVGIVGNMMVILVVLTTKHMRTPTNCYLVSLAAADLMVLTAAGLPNITD--ALRGQWVYGYAGCLGITYFQYLGINASSCSITAFTVERYIAICHPIKAQFLCTLSRAKKIIMLVWALTSVYCVMWLFLSDTK-KLVYDNVVLLT--CAYKVSRSHYLPIYFTDFTVFYVLPLLLATVLYGLIARILFLNPLPADPKASSSRGCGDSQRRESSRRQEPQPGVTKMLAVVVVLFAVLWMPYRTLVVVNSFLEKAYLDTWFLLFCRLCIYLNSAINPVIYNAMSQKFRTAFKKLCQCGPQRMEKPVTYSVALTYSVIKDTSNG 353
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Medaka
Match: trhr3 (TRHR3 protein [Source:NCBI gene;Acc:100533511]) HSP 1 Score: 195.667 bits (496), Expect = 1.940e-58 Identity = 129/324 (39.81%), Postives = 189/324 (58.33%), Query Frame = 1
Query: 154 MVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXX---------XXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKS--SLTCRQIFSSKAQEYLDCSEMKDPS 1092
++I +GI GN +VV+VV ++ M TPTNC+LVSL++AD+I LL++ LP IS+ + W + C +LQ+ N S+ SIT F+ ER++AIC + AQ +CT++RA +II G+W+F LY + W +L + Y N ++N C YR++ +Y D +FY+ PLIV +VLY I L R G + + ++ ++ KML+ VVVLFA+LW+PYR+ +V NSF + Y D WF+LF R +Y NSAINPI+YN MS KFR AF+ CR+ +K + CS MK+ S
Sbjct: 36 LLICGVGIAGNVMVVLVVLRTKHMVTPTNCYLVSLAVADLIVLLAAGLPNISDV---VACWIYGYTGCLFITYLQYLGINVSSCSITAFTIERYIAICHSIKAQFICTVSRAKRIIAGVWIFTSLYCTMWFFLVDID-ETVYANGVVVN--CGYRVSRSLYMPIYFLDFTVFYVVPLIVATVLYGLIARILFISPLPSDRAGGGSVHQGHYNSTSSANKGAIAARKQITKMLVVVVVLFALLWMPYRTLVVINSFIDPPYHDTWFILFCRMCIYSNSAINPIIYNLMSQKFRVAFRKLCKCGCRR-GEAKYDAPIYCSVMKNLS 352
BLAST of Thyrotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000077152.1 (SMESG000077152.1) HSP 1 Score: 484.952 bits (1247), Expect = 9.184e-174 Identity = 240/240 (100.00%), Postives = 240/240 (100.00%), Query Frame = 1
Query: 52 MNDTSTSDISYPIAQFITVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKF 771
MNDTSTSDISYPIAQFITVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKF
Sbjct: 1 MNDTSTSDISYPIAQFITVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKF 240
BLAST of Thyrotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000076461.1 (SMESG000076461.1) HSP 1 Score: 249.98 bits (637), Expect = 3.708e-80 Identity = 141/295 (47.80%), Postives = 205/295 (69.49%), Query Frame = 1
Query: 109 LYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSA 993
+YYS YK I I+ +IL G+IGN V I++ F++ M + TNC+LVS+++AD++ LLS+I+P + + +N C + ++LQ+ S N+SA++IT FSFERW+AIC P+ A MCT++RAVKI+ GIW+FNL+YNSSW+YLT + ++ +N S VCT+R +Y+ D ++FY PL++T+ LY I+ TL+ + S G+ + SK++V+KML+ VV+LFA+LWLPYR+ +VYNSFA K YLDLWF+LFAR MV++NSAINPILYNA+S
Sbjct: 24 IYYSKHYKAISIISSTIILFFGLIGNLSVSIILTFAKNMQSSTNCYLVSVAVADILVLLSTIVPFLYNINQDINISLLPSWGCSLIIYLQYLSVNSSALTITSFSFERWVAICYPMKAHTMCTISRAVKIVIGIWIFNLIYNSSWIYLTGI-VKKGPLNGS-YKSVCTFRFERRKYMNIYMFDFMLFYCIPLLLTTFLYCAIIRTLVKRPMSG-TTSGRD--PRKHMNHSKMQVVKMLMAVVILFAMLWLPYRALMVYNSFASKSYLDLWFLLFARIMVFINSAINPILYNALSG 313
BLAST of Thyrotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000066580.1 (SMESG000066580.1) HSP 1 Score: 228.024 bits (580), Expect = 1.202e-71 Identity = 147/311 (47.27%), Postives = 211/311 (67.85%), Query Frame = 1
Query: 91 AQFITVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSL 1023
+Q ++ YY +Y +G I ++ L++G +GN +V+ VV S M TPTNC+LVSL+IAD+ L+ ++LP I+E+ + +++W+ LC I VFLQ+ + S++SIT FS ERW+AIC P+ A+ +CT+ RA II IW LYN WLYL K + + NS + CT+RL+ +Y + +Y+ D+I+FY PL++ VLY+ IV+ L + S R +G + KS+++VIKMLI VV+LF VLWLPYR+ +VYNSF++K Y D WF LFAR+MV +NSAINPILYNAMS KFR++FK L
Sbjct: 11 SQLSSLKYYQPLYIWLGCIQSILYLTVGCVGNAMVITVVTRSSNMITPTNCYLVSLAIADICLLIVTVLPNITEFMNPIDHWQLGAFLCTILVFLQYYCCSTSSLSITFFSIERWVAICFPMKAKTLCTIKRARIIIICIWFCCFLYNMMWLYLAHTKTKR-FPNSLMSYEKCTFRLHRKYYKAIYMSDIILFYFLPLVIIFVLYVHIVMVLF--QSSMRRSIGSS----DRNRKSRIQVIKMLIVVVILFVVLWLPYRTLVVYNSFSKKAYEDYWFRLFARNMVLMNSAINPILYNAMSEKFRRSFKKIL 314
BLAST of Thyrotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000036494.1 (SMESG000036494.1) HSP 1 Score: 221.476 bits (563), Expect = 5.348e-69 Identity = 129/328 (39.33%), Postives = 198/328 (60.37%), Query Frame = 1
Query: 112 YYSNIYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNYWRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLIIFYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEKKYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEYLDCSEMKDPSG 1095
++S++Y I + +L +G +GN +V+IVV +PTN +L++L+ AD+I L +I+P I E + +N+W LCP+ VFLQ+ S N S + IT FS ERW+AIC P+ A+++ + + II+ W+ + +Y+S+W YL + IN CT+R N EY + +Y+ D +FY PL++ SV YI I TL +K L K S++++IKML+ V + FA+L LPYR+ +VYNSF++KK+LD WF+LF+++M+ +NSA+NPI YN MS FR+AFK L + IF +K +C E K
Sbjct: 15 HFSHLYVFINAFQSLNLLVIGSLGNIMVIIVVLRRAVSGSPTNLYLLTLAAADLIFLNVTIIPNIIELNYPINHWHLGTFLCPVLVFLQYYSCNTSVIFITLFSHERWVAICYPMKARLVSNIDKVRVIIWSTWISSFIYHSAWFYLAKTNIEK--INMKYFQK-CTFRFNREYYKFIYIFDASMFYFLPLLLMSVFYIHIAYTLYVQKPFNLHTFSKS-------RSSRIQIIKMLMLVSISFAILCLPYRTLVVYNSFSKKKFLDFWFLLFSKNMMLLNSAVNPIFYNVMSENFRRAFK-KLILQIIFGTKFNPSHNCYERKRSGS 331
BLAST of Thyrotropin-releasing hormone receptor vs. Planmine SMEST
Match: SMESG000044227.1 (SMESG000044227.1) HSP 1 Score: 115.161 bits (287), Expect = 1.564e-28 Identity = 96/345 (27.83%), Postives = 166/345 (48.12%), Query Frame = 1
Query: 124 IYKIIGTINLMVILSLGIIGNFLVVIVVYFSRGMHTPTNCFLVSLSIADMITLLSSILPVISEYHSKMNY-WRFAPELCPITVFLQFCSANASAMSITCFSFERWMAICKPLTAQVMCTLTRAVKIIFGIWVFNLLYNSSWLYLTTLKYRESYINSSILNPVCTYRLNPEYLRIVYLCDLII------------------FYITPLIVTSVLYIDIVLTLLNKKDSKLRIVGKKFXXXXXXXXXXXXXXXXXXTVVVLFAVLWLPYRSWIVYNSFAEK-KYLDLWFVLFARSMVYVNSAINPILYNAMSAKFRKAFKSSLTCRQIFSSKAQEYLDCSEMKDPSGN 1098
+Y+I+ + +L+ G GN V+ ++ +HT TN +L +L+++D++ LL+ LP Y Y W C + L S+ S ++IT F+ ER++AIC PL Q++ T+ R+ ++ IW+ + L++ + L L Y ++ N + N C LN E + + +L + F++ PL V VLY I LTL +K ++ + + + VI+MLI VV+ F + W P+ + + +F LD + S+ Y++S +NPI+YN +S+KFRKAFK + LDC++ + N
Sbjct: 1 MYRILQGLIYTCVLTFGFCGNICTCTVIISNKYLHTTTNIYLFNLAVSDILLLLTG-LPSEILYSVGNGYPWILGNFYCHLRAMLLEMSSIVSVLTITAFTIERYIAICHPLKQQIISTMQRSFFVVIFIWLISSLFSLPYGVLCKLDYMLTFPNMTANNSECFDALNSEVYKPIEDSNLCVGPRNSSFFNYIIRTSTFLFFLIPLAVLLVLYFHIALTLWRRKITRSHLSNHS--------RGRNGVIRMLIFVVIAFFISWAPFHTQRILATFRHSVDILDFIIYYLSGSLFYMSSVLNPIVYNIISSKFRKAFKMTFC------------LDCNKSDQTNSN 324 The following BLAST results are available for this feature:
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Thyrotropin-releasing hormone receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034409 ID=SMED30034409|Name=Thyrotropin-releasing hormone receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1187bpback to top protein sequence of SMED30034409-orf-1 >SMED30034409-orf-1 ID=SMED30034409-orf-1|Name=SMED30034409-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=359bp MNDTSTSDISYPIAQFITVLYYSNIYKIIGTINLMVILSLGIIGNFLVVIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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