Prolyl 4-hydroxylase subunit alpha-2

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            ++I+ +L    L     FT++  +T   +++  L  +L ++    +  ++ +K + + +    +   ++PE ++ +P+ A+ L++RL   W E E  +L    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +  + LT++ CFE+G  ++ E DY++   W  +A  +++E   S  +K+ +LDYLS+  ++Q +L +AL LTK+  ++DP + RA+ N  YF       ++ N     D  D  T      V     D   E + YE LCRGE     P     L CRY+  +    F+L P K+E  + KPRI+ +HD+I+D EIE +K L+  +LRRAT+ N ITG LE  +YRISKSAWL    N +  RIN+RIQ +TG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    5 ILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGF--ISNLTIQR-QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531          

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            ++I+ +L    L     FT++  +T   +++  L  +L ++    +  ++ +K + + +    +   ++PE ++ +P+ A+ L++RL   W E E  +L    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +  + LT++ CFE+G  ++ E DY++   W  +A  +++E   S  +K+ +LDYLS+  ++Q +L +AL LTK+  ++DP + RA+ N  YF       ++ N     D  D  T      V     D   E + YE LCRGE     P     L CRY+  +    F+L P K+E  + KPRI+ +HD+I+D EIE +K L+  +LRRAT+ N ITG LE  +YRISKSAWL    N +  RIN+RIQ +TG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    5 ILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGF--ISNLTIQR-QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531          

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            ++I+ +L    L     FT++  +T   +++  L  +L ++    +  ++ +K + + +    +   ++PE ++ +P+ A+ L++RL   W E E  +L    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +  + LT++ CFE+G  ++ E DY++   W  +A  +++E   S  +K+ +LDYLS+  ++Q +L +AL LTK+  ++DP + RA+ N  YF       ++ N     D  D  T      V     D   E + YE LCRGE     P     L CRY+  +    F+L P K+E  + KPRI+ +HD+I+D EIE +K L+  +L RATV +  TGKL  A YR+SKSAWL    N +  RIN+RIQ +TG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    5 ILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGF--ISNLTIQR-QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531          

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            ++I+ +L    L     FT++  +T   +++  L  +L ++    +  ++ +K + + +    +   ++PE ++ +P+ A+ L++RL   W E E  +L    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +  + LT++ CFE+G  ++ E DY++   W  +A  +++E   S  +K+ +LDYLS+  ++Q +L +AL LTK+  ++DP + RA+ N  YF       ++ N     D  D  T      V     D   E + YE LCRGE     P     L CRY+  +    F+L P K+E  + KPRI+ +HD+I+D EIE +K L+  +L RATV +  TGKL  A YR+SKSAWL    N +  RIN+RIQ +TG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    5 ILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGF--ISNLTIQR-QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531          

Query:  336 LFLLFF--IPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHV--TPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRIN--ENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYY----VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCA 1889
            L + +F  +   + E FT++  +T    ++ +L  +L E+    +A +  +K++   +    +    + E Y+ +P+ AY L++RL   W      L+  D     IAN   Q   + P  +D  G+  AL+RLQDTY++    I+ G +   +    L+   CF +G  ++ E DY++ V W  +   +++  E   + K ++LDYLS+  F+  +L +AL LT+    +DP + RA  N  YF Q  +  R   +       +L T    I  RP   D   E   YE+LCRGE     P     L CRY+     P    L+ P KEE  +  P IV Y+D+++D EIE IK ++  KL RATV++  TG L  A+YR+SKS+WL  D + +  R+N R+Q +TG+ ++TAE LQV NYG+GG YEPHFDF+R  E ++F+    GNR+AT L YMSDVEAGGATVF  +GA IWPKKG A FW+NLL SGEGD  TRHAACPVL+G KWV NKWFHERGQEF RPC 
Sbjct:    8 LLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPA-LEDLVLQDSAAGFIANLSVQR-QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEERE-KTLTNQTEAELATP-EGIYERPV--DYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQ--LLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCG 530          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKS-IH--VTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENF---DSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRI-NENVKS-EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNL-HSLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 1892
             +L +     L   ++FTA+ DL     ++  +   + ++    +A +  L+ +    +H     E+  PE ++ NP+ AYLLI+RL   WK+   I+++   +    +   NR++  + + P ++DL G+  AL+RLQDTY + T  ++NGII   + SN L+    FE+G  ++ +KDY++ + W   A  +I NEN  + E+ ++L+YL++  ++Q N+R+AL+LTK   KI P + RA  N  ++    Q              D+  DL  I  +   +D   E   YEALCRGE     P   + L+C       +  L P+K E L   P  V++ ++I+D+EIE IK L+  KL+RATVQNS TG+LE A YRISKSAWL+ D++ + +R+N RI+  T +N  T+EELQV NYG+GGHY+PHFDFARK E N+F++   GNR+AT+LFYMS  E GGATVF  +G  ++P K  A FW+NL   GEGDL TRHAACPVLLG KWV NKW HE+GQEFTRPC L
Sbjct:    3 AVLLVCLLAGLAHADLFTAIADLQHMLGAEKDVTTIIDQYIEAERARLDDLRRYAHEYVHRNAHAESVGPE-FVTNPINAYLLIKRLTTEWKKVENIMLNNKASTFLKNITDNRVRSEVKF-PGEEDLSGAATALLRLQDTYSLDTLDLSNGIIGGEKVSNKLSGHDTFEVGRSAYNQKDYYHCLMWMQVALVKIENENPPTIEEWEILEYLAYSLYQQGNVRRALSLTKRLAKIAPNHPRAKGNVKWYEDMLQG------------KDMVGDLPPIVNKRVEYDGIVERDAYEALCRGEIPPVEPKWKNKLRCYLKRDKPFLKLAPIKVEILRFDPLAVLFKNVIHDSEIEVIKELASPKLKRATVQNSKTGELEHATYRISKSAWLKGDLDPVIDRVNRRIEDFTNLNQATSEELQVANYGLGGHYDPHFDFARKEEKNAFKTLNTGNRIATVLFYMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVSNKWIHEKGQEFTRPCGL 520          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKA----FTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLN-----YLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQ--EQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRT-YEALCRGESTIKNPNLHSLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRNATKSTLNRFV 1931
            + L +L  I     ++FT++ D+     ++  +   L ++ ++ +  +  LK     ++K   ++ EN   +  I NP+ A+LLI+R I  WKE     I +  N +   N +  + +       P  DDL G+   L+RLQDTY++ T  +A+G I  ++ + + +++ CFEI   ++ E D+++ V W  EA  R+ + V+   E   +L+YL+F  +KQNNL+ AL LT+E  K++P + RA  N  ++    EQ+ +R S         D+  +L  I  R      GN  RT YEALCR E  +   ++  L C Y     + +  P+K E     P  V++ D+I+D+E+  I+ L+  KL RATV +S+TGKL  A YRISKSAWL+    ++ E +N RI  +T + +ETAEELQ+ NYGIGGHY+PHFD A+K E  SFES   GNR+AT+LFYMS    GG TVFT+  + I P K  A FW+NL   G+G+  TRHAACPVL+G KWV NKW HE+G EF RPC L      S   RFV
Sbjct:    3 LALLVLATIGYAVADLFTSIADMQNLLETERNIPKILDKYIHDEEERLVQLKKLSEEYSKKNEISIENGLKD--ITNPINAFLLIKRKIFDWKE-----IESKMNANKAGNVVSSITDDSYGVRYPTADDLSGAAIGLLRLQDTYRLDTKDLADGKIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVMWMEEAQRRLGDEVEPTVEVEDILEYLAFALYKQNNLKHALKLTEELYKMNPTHPRAKGNVKWYEDLLEQEGVRRS---------DMRKNLPPIQNRRPDSVLGNTERTMYEALCRNEVPVSQKDISRLYCYYKRDRPFLVYAPIKVEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLKEWEGDVVETVNKRIGYMTNLEMETAEELQIANYGIGGHYDPHFDHAKKEESKSFESLGTGNRIATVLFYMSQPSHGGGTVFTEAKSTILPTKNDALFWYNLYKQGDGNPDTRHAACPVLVGIKWVSNKWIHEKGNEFRRPCGLK----SSDYERFV 532          

Query: 1284 KEETLFHKPRIVIYHDLIN----DNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQL-VTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 1892
            K E L  +P I+ YH+ ++       ++  + L + +L+ +      T   E +  R +   WL         RI   +Q  +  ++L TAE  Q+++Y   G+Y PH+D+   +         GNR+AT+L  +   + GG TVF ++   I PK G    W N L +GE +  T HAACP+  G+K     W HE+ QEF+ PCAL
Sbjct:   63 KVEILSSEPFILQYHNQVHRRLAKRAVQEAEALRLEQLKIS----GFTTTPEKSQVRAANGTWLIHTGRPSFARIFEGLQANINSLDLSTAEPWQILSYNADGYYAPHYDYLNPATNVQLVEGRGNRIATVLVILQIAKKGGTTVFPRLNLNIRPKAGDVIVWLNTLSTGESNSQTLHAACPIHEGTKIGATLWVHEKKQEFSLPCAL 266          

Query: 1248 YVPHYYFLLGPMKEETLFHKPRIVIYHDLIN----DNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQL-VTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHER 1862
            Y  H + L+   K E L  +P I+ YH+ ++       ++  + L + +L+ +      T   E +  R +   WL         RI   +Q  +  ++L TAE  Q+++Y   G+Y PH+D+   +         GNR+AT+L  +   + GG TVF ++   I PK G    W N L +GE +  T HAACP+  G+K     W HE+
Sbjct:   53 YRLHKHLLI--RKVEILSSEPFILQYHNQVHRRLAKRAVQEAEALRLEQLKIS----GFTTTPEKSQVRAANGTWLIHTGRPSFARIFEGLQANINSLDLSTAEPWQILSYNADGYYAPHYDYLNPATNVQLVEGRGNRIATVLVILQIAKKGGTTVFPRLNLNIRPKAGDVIVWLNTLSTGESNSQTLHAACPIHEGTKIGATLWVHEK 256          

Query: 1260 YYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQ-NSITGKLEFANYRISKSAWLRTDVNELTERINLRIQ-LVTGINLETAEELQVVNYGIGGHYEPHFDFA---RKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQ 1868
            Y + + P+  E +   P +VIY +L++  +      L+  + R   +Q  S  G      +R +  +++  + + +T  I ++ Q  + G+NL  AE    ++Y  GGHY  H+D+     K + + + ++ GNR+ TL+F +   E GG TVF  IG+ +    G A FW+N     E ++ + H  CP+  G K +   W     Q
Sbjct:   76 YVYNMLPVDMEIISWAPTLVIYRNLMSPRQTASF--LNFIEQRDLEIQKTSDFGTSIETTHRRANGSFIPPEDSNVTVEIKMQAQKRIPGLNLTVAEHFSALSYLPGGHYAVHYDYLDYRSKQDYDWWMNKTGNRIGTLIFVLKPAEKGGGTVFPSIGSTVRANAGDAFFWFNAQADEEKEMLSNHGGCPIYEGRKVIATIWIRAYNQ 281          

Query:  369 GEVFTALVDLTQSFNSKLQLGNNLLEF--TNEAKAHIQSLKAFTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQ--QLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRI-----NENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQE---QQNIRNSNSFFKGDIGD---LFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFL-LGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
            GEV+TAL ++ +   ++  L  NL  +    E K +    K        +  + +   Y++NP+ AYLL +RL   W++    L+  D   D + N  Q   LL + P+ +DL G+  AL+RLQDTY++ T  +A G +   + S  ++S  CFE+G +S+   DY++ V W +EA  R+     N      K  +L+YL+F  +K+ N+  AL +T E  ++ P + RA+ N+ ++ +E   Q  +R      KGD G      +DL      P+  D   E R YE LCRGE      +L SL+CRY      FL LGP+K E +   P IVIYHD + D+EI+ IKR++  + RRATVQNS+TG LE ANYRISKSAWL+T  + + E +  R   +TG+++++AEELQVVNYGIGGHYEPHFDFARK E  +FE   +GNR+AT+LFYMSDVE GGATVFT +   ++PKKG AAFW NL   G+GD+ TRHAACPVL G+KWV NKW HERGQEF RPC L  +
Sbjct:   23 GEVYTALAEMEELLETESVLITNLEGYIRVQEDKLNFLKNKMDEYQREHSDASHDITAYVSNPINAYLLTKRLTTDWRQ-VENLMEHDVGTDFLQNITQYRSLLKF-PSDEDLNGAAVALLRLQDTYQLDTSSVARGKLNGIQYSTEMSSDDCFELGRQSYVNHDYYHTVLWMNEAMARMLEEPTNHTQSFTKADILEYLAFSTYKEGNIESALTMTNELLQLLPHHERANGNKRFYEKEIAQQLQLRK----MKGDDGTDEMPKSDLPVAKSDPAIFDM-TERRAYEMLCRGELKPSPSDLRSLRCRYVTNRVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMARPRFRRATVQNSVTGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEPHFDFARKEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQGDVRTRHAACPVLTGTKWVSNKWIHERGQEFRRPCDLEED 544          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPENQNP----ETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYL----PNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEK---SNSLTSQQCFEIGLRSFE-KDYFYFVEWASEAYYR--------INENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYY---VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATV---QNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRNATK 1910
            +IL LL   P+  G+ ++A+ +L +  + +  +     E+   A+   ++LK F   I    E QN     E Y  NP+ A++ I+RL+  WK      +    NF++  N +   L  +    P ++DL G+  AL+RLQ+ Y++ T  +A+G++   EK     SL++  CFE+G    E K+Y Y  EW  EA  R        I+ NV    +++L++LS  F    NL+ A  L  E     P +  A +N+I +  E Q  R  +   +  +     +L  I    +  ++   ++ Y  +CRGE         +L+C  Y   VP  Y+ L P K E L   P +   H+++ D+EI+ I       + R+ V   +NS T ++     RIS++ WL  D N    +I  R++ VTG++ E+AE LQ+VNYGIGG YEPHFDF      + F S  GNRL T LFY++DV  GGAT F  +   + P KG+   W+NL  S   D  T+HA CPVL GSKW+ N+WFH   QEF RPC L+ +  K
Sbjct:    6 IILSLLCVFPVN-GDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQID---EQQNDRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEARKRLHGKPLGFISPNVSD--VEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEEALKNKILY--EGQLARERSFAPRKQV-----ELPQI----AEKEQKESYKLYTQVCRGELHQSPREQRNLRCWLYHQGVP--YYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVGQSENSTTSEV-----RISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSVF-SWKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQGSKWICNEWFHVGAQEFRRPCGLSSDEGK 533          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPEN--QNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDEN----FDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFE-KDYFYFVEWASEAYYRINENVKSEKIKLLDYLS--FGFFKQNNLRQ-ALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQN-SITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
             +LFL+  +    GE F++   L + F +++ L   L  + NE   H ++L++   +I V   N     + Y+NNP+ A+ LI+RL   W E F   ++ D +     D++A+  + L    P++DD  GS  AL RLQ TY++   ++A+GI+   +   +++ Q CF +G   +  +DY + V W  ++   + E     +   LD++     + ++    + AL+L      I+P      +   +  + +Q +        GD   L   L     RP  +    EFR YE +CRGE         +L+CR       +   P K E L   P +V  H +I   + + +++ +  +++R+TV +    G    A +R S+ A      N  T+ ++  +   +G+N++ AE+LQV NYGIGGHYEPH+D   ++ I       GNR+AT ++Y++DVEAGG T F  +   + P++G+  FW+NL PSG+ D  T+HAACPVL GSKW+ N W  ER Q+  RPC L R 
Sbjct:    6 CVLFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRVEHLNAADGIDDYLNNPVNAFRLIKRLHSDW-ETFEGSVTADSSRSNYLDTMASLKENL--SFPSQDDFVGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQLLGEQSYGSESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEP------DQRSHLLEARQQLEEL--ITDGDKNGL---LHLTARRPGDYHESREFRMYEQVCRGELAPLPSKQRNLRCRLRKSRLGY--APFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEGDLHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQGSKWIANVWIRERNQDNVRPCDLERG 524          

Query:  327 MVILFLLFFIPLTRGEV----FTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHV--TPENQNPETYINNPLKAYLLIQRLIRYWK--EEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFE-KDYFYFVEWASEAYYRINENVKSEKIKL-------------LDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVP-HYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
            +V+L  L F+ L +G +    F+++  L    +++  L   L    N  +  +Q L++   SI    T    + E Y+ NP+  Y L++RL   W   E    L++ + NF++     +  L+Y P+++D++G+  ALVRLQ TYK+   ++A GI+   +  + ++ Q CFE+G + FE +DY     W  E+  R+          L             ++  +   F+  +   A  L++   + DP  +R             ++ +  +    DI D++     +     ++    EF  YE +CRGE  +       L+CRY    H Y  L P+K E     P +  +HD+++  +I  ++ +++ ++ R+TV     G+L+ + +R+SK+AWL  + +     +   ++  TG++    E+LQV NYG+GGHYEPH+DF R  + N + +E GNR+AT +FY+S+VE GGAT F  +   + P+ G   FW+NL  S + D  T+HA CPVL GSKW+ N W HE  Q F RPC + R+
Sbjct:    4 LVLLVGLIFL-LAQGSLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAASDTENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEEMNFNATR---EYGLSY-PSQEDVEGAALALVRLQSTYKLDVAQVAQGILNGVKYGSDMSWQDCFELGQQLFEMEDYNNTKVWLRESMERLRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIR-----------NWHLGDKGTAPPEDIDDVY-----LPKHSDSYSLSQEFAKYEKVCRGE--VHPIVRQELRCRYSRGNHPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPGGQLKKSAFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFR--DPNHYPAEEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVLKGSKWIGNVWIHEVTQTFARPCDVFRD 526          

Query:  381 TALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPEN--QNPETYINNPLKAYLLIQRLIRYW-----KEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKSEKIKLLDYLSFGF---FKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGE-STIKNPNLHSLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNR 1898
            T++  + +  + + QL +NL ++  E +  +Q+++    S+ +  +    + E Y++NPL ++ LI+R+ R W       + P+ IS  E       RIQ+L  ++P   D++ ++ AL R+Q TY +K  +I++G +   + + SLT    + +G   F +K+Y     W  ++            + L++  S        +N +R   A T     +  LN  A   ++       N  +     K    +        N  P           Y+  CRG+     +  L+ L  R   P  + +L P+K E +   P +V+YHD+++  EI+ ++ ++   L+RATV  + +G+ E    R SK AW     N LT R+N RI  +TG NL  +E LQ++NYG+GGHY+ H+DF  K+  N   +  G+R+AT+LFY++DVE GGATVF  I   ++P++G+   W+NL  +G+ D  T HAACPV++GSKWV NKW  ER Q F+RPC   R
Sbjct:   34 TSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSLRLENDKARSSTEEYLSNPLNSFSLIRRMNRDWIIWQLYMDDPVGISQVE-------RIQELREHMPTHTDVEEAVTALDRIQSTYGLKVPEISHGFLNGKQYNVSLTVLDTYAMGQILFDQKNYLAAASWIYQS------------VVLMEAFSMAAPLEISKNEVRMVYAET-----LLKLNQHADALKVVNIALTDNPHDIKLLLKKSEIETMIRTGTNNAPPVKVQATGVPTAYQIGCRGQFPPSADSKLYCLYNRTTSP--FLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQASSGRNEVVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQHYDFFNKTNSN-MTAMSGDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMWYNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIREREQIFSRPCLKKR 524          

Query:  372 EVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTK---SIHVTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            + FT+   +T    ++  L  +L E+  + +  ++ +K +     S+ +T   Q+PE ++ +P+ A+ L++RL   W + E  +L  T   F  I+N   Q   Y P  +D  G+  AL+RLQDTY++  + I++G +      + +T + C+E+G  ++ + DY++   W ++A  +++E  +S  +K+ ++DYLS+  ++Q  L +AL LTK   K+DP + RA+ N  YF  + +  R + +  K +      D      R  + D   E + YE LCRGE     P   S L CRY   +     LL P+K+E  + +PRIV YH++I+D+EIE +K ++  +LRRAT+ N ITG LE A YRISKSAWL    +   ERIN RI+ VTG+ ++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVFT +GA +WPKKG A FW+NL PSGEGD STRHAACPVL+G+KWV NKW HERGQEF RPCAL+
Sbjct:   20 DFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDSLTITA-TQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTNGF--ISNLTVQR-QYFPTDEDQTGAAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTELWMAQALSQLDEGEESPIDKVTVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQLEKQRKAENEKKEEDQKRVLDKRDAQ-RKRSKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSNNNRNPRLLLAPVKQEDEWDRPRIVRYHEIISDSEIETVKEMAKPRLRRATISNPITGVLETAPYRISKSAWLSGYEHSTIERINQRIEDVTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCALS 533          

Query:  372 EVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTK---SIHVTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            + FT+   +T    ++  L  +L E+  + +  ++ +K +     S+ +T   Q+PE ++ +P+ A+ L++RL   W + E  +L  T   F  I+N   Q   Y P  +D  G+  AL+RLQDTY++  + I++G +      + +T + C+E+G  ++ + DY++   W ++A  +++E  +S  +K+ ++DYLS+  ++Q  L +AL LTK   K+DP + RA+ N  YF  + +  R + +  K +      D      R  + D   E + YE LCRGE     P   S L CRY   +     LL P+K+E  + +PRIV YH++I+D+EIE +K ++  +LRRAT+ N ITG LE A YRISKSAWL    +   ERIN RI+ VTG+ ++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVFT +GA +WPKKG A FW+NL PSGEGD STRHAACPVL+G+KWV NKW HERGQEF RPCAL+
Sbjct:   20 DFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDSLTITA-TQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTNGF--ISNLTVQR-QYFPTDEDQTGAAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTELWMAQALSQLDEGEESPIDKVTVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQLEKQRKAENEKKEEDQKRVLDKRDAQ-RKRSKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSNNNRNPRLLLAPVKQEDEWDRPRIVRYHEIISDSEIETVKEMAKPRLRRATISNPITGVLETAPYRISKSAWLSGYEHSTIERINQRIEDVTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCALS 533          

Query:  372 EVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTK---SIHVTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            + FT+   +T    ++  L  +L E+  + +  ++ +K +     S+ +T   Q+PE ++ +P+ A+ L++RL   W + E  +L  T   F  I+N   Q   Y P  +D  G+  AL+RLQDTY++  + I++G +      + +T + C+E+G  ++ + DY++   W ++A  +++E  +S  +K+ ++DYLS+  ++Q  L +AL LTK   K+DP + RA+ N  YF  + +  R + +  K +      D      R  + D   E + YE LCRGE     P   S L CRY   +     LL P+K+E  + +PRIV YH++I+D+EIE +K ++  +L+RATV + ITGKL  A YR+SKSAWL    +   ERIN RI+ VTG+ ++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVFT +GA +WPKKG A FW+NL PSGEGD STRHAACPVL+G+KWV NKW HERGQEF RPCAL+
Sbjct:   20 DFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDSLTITA-TQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTNGF--ISNLTVQR-QYFPTDEDQTGAAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTELWMAQALSQLDEGEESPIDKVTVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQLEKQRKAENEKKEEDQKRVLDKRDAQ-RKRSKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSNNNRNPRLLLAPVKQEDEWDRPRIVRYHEIISDSEIETVKEMAKPRLKRATVHDPITGKLTTAQYRVSKSAWLSGYEHSTIERINQRIEDVTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCALS 533          

Query:  372 EVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPEN--QNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANG----IITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQE---QQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVP--HYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 1892
            + FT++  +T    ++  L  +L ++    ++ ++ +K + + +        Q+PE ++ +P+ A+ L++RL   W E E  +L    + F  I+N   Q   Y PN +D  G+  AL+RLQDTYK+ T  I++G    + T     ++LT + CFE+G  ++ + DY++   W ++A  +++E  +S  E    LDYLS+  ++Q  L +AL  TK    ++P + RA  N  YF  +   Q+      S  +    +  T        P       E R YE LCRGE     P     L CRY+    H ++ +GP+K+E  + +PRI+ YH++I + EIE IK LS  +LRRAT+ N ITG LE A+YRISKSAWL    + + +RIN RI+ +TG+N++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA + P KG A FW+NL PSGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L
Sbjct:   24 DFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAEKLDALTATAVQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGF--ISNLTIQR-QYFPNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELWMAQALKQLDEGEESSVEIATALDYLSYSVYQQGELERALEYTKRLLTVEPEHQRALGNLKYFDYQLAKQKKAEKEQSTKEESKKEQETSDGKKEYLP-------EKRKYEKLCRGEGLKMTPRRQKHLFCRYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATISNPITGVLETAHYRISKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGL 537          

Query:  372 EVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPEN--QNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANG----IITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQE---QQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVP--HYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 1892
            + FT++  +T    ++  L  +L ++    ++ ++ +K + + +        Q+PE ++ +P+ A+ L++RL   W E E  +L    + F  I+N   Q   Y PN +D  G+  AL+RLQDTYK+ T  I++G    + T     ++LT + CFE+G  ++ + DY++   W ++A  +++E  +S  E    LDYLS+  ++Q  L +AL  TK    ++P + RA  N  YF  +   Q+      S  +    +  T        P       E R YE LCRGE     P     L CRY+    H ++ +GP+K+E  + +PRI+ YH++I + EIE IK LS  +LRRAT+ N ITG LE A+YRISKSAWL    + + +RIN RI+ +TG+N++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA + P KG A FW+NL PSGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L
Sbjct:   24 DFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAEKLDALTATAVQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGF--ISNLTIQR-QYFPNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELWMAQALKQLDEGEESSVEIATALDYLSYSVYQQGELERALEYTKRLLTVEPEHQRALGNLKYFDYQLAKQKKAEKEQSTKEESKKEQETSDGKKEYLP-------EKRKYEKLCRGEGLKMTPRRQKHLFCRYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATISNPITGVLETAHYRISKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGL 537          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSI-HVT-PENQNPETYINNPLKAYLLIQRLIRYW-KEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGEST-IKNPNLHSLKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            ++L LL        + FT++  +T   N++  L  +L ++    +  +  +K +   + H+T    ++PE ++ +P+ A+ L++RL   W K E  IL    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +   SLT++ CF++G  ++ + DY++   W  +A  +++   +S  +K+ +LDYLS+  ++Q +L +AL LTK   ++DP + R + N  YF    + I +  S           +L     RP  H    E + YE LCRGE   + +     L CRY+  +     +L P K+E  + KPRIV YHD+I+D EI  +K L+  +LRRAT+ N ITG LE A YRISKSAWL    + +  R+N RI+ VTG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDVEAGGATVF ++GA ++PKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    6 LVLPLLGLFSCAHADFFTSIGHMTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTATKDPEGFLGHPVNAFKLMKRLNTEWVKLENLILKDISDGF--ISNLTIQR-QYFPNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGEESSLDKVMVLDYLSYAVYQQGDLDKALTLTKLLLELDPEHQRGNGNLRYF----EYIMSKESNKSSSSPSEGAELGTRKGRPKDH--LPERQKYEKLCRGEGVKMTSRRQKRLFCRYFDGNKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRISKSAWLSAYEDPVVARLNRRIEGVTGLDMSTAEELQVANYGMGGQYEPHFDFARKDEPDAFKELGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLFESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCNLS 528          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSI-HVT-PENQNPETYINNPLKAYLLIQRLIRYW-KEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGEST-IKNPNLHSLKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            ++L LL        + FT++  +T   N++  L  +L ++    +  +  +K +   + H+T    ++PE ++ +P+ A+ L++RL   W K E  IL    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +   SLT++ CF++G  ++ + DY++   W  +A  +++   +S  +K+ +LDYLS+  ++Q +L +AL LTK   ++DP + R + N  YF    + I +  S           +L     RP  H    E + YE LCRGE   + +     L CRY+  +     +L P K+E  + KPRIV YHD+I+D EI  +K L+  +LRRATV +  TGKL  A YR+SKSAWL    + +  R+N RI+ VTG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDVEAGGATVF ++GA ++PKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    6 LVLPLLGLFSCAHADFFTSIGHMTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTATKDPEGFLGHPVNAFKLMKRLNTEWVKLENLILKDISDGF--ISNLTIQR-QYFPNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGEESSLDKVMVLDYLSYAVYQQGDLDKALTLTKLLLELDPEHQRGNGNLRYF----EYIMSKESNKSSSSPSEGAELGTRKGRPKDH--LPERQKYEKLCRGEGVKMTSRRQKRLFCRYFDGNKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATVHDPQTGKLTTAQYRVSKSAWLSAYEDPVVARLNRRIEGVTGLDMSTAEELQVANYGMGGQYEPHFDFARKDEPDAFKELGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLFESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCNLS 528          

Query:  375 VFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSI-HVT-PENQNPETYINNPLKAYLLIQRLIRYW-KEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKS----NSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGEST-IKNPNLHSLKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            VF+    +T   N++  L  +L ++    +  +  +K +   + H+T    ++PE ++ +P+ A+ L++RL   W K E  IL    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +  N+       SLT++ CF++G  ++ + DY++   W  +A  +++   +S  +K+ +LDYLS+  ++Q +L +AL LTK   ++DP + R + N  YF    + I +  S           +L     RP  H    E + YE LCRGE   + +     L CRY+  +     +L P K+E  + KPRIV YHD+I+D EI  +K L+  +LRRAT+ N ITG LE A YRISKSAWL    + +  R+N RI+ VTG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDVEAGGATVF ++GA ++PKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    9 VFSICCHMTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTATKDPEGFLGHPVNAFKLMKRLNTEWVKLENLILKDISDGF--ISNLTIQR-QYFPNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGNKTCVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGEESSLDKVMVLDYLSYAVYQQGDLDKALTLTKLLLELDPEHQRGNGNLRYF----EYIMSKESNKSSSSPSEGAELGTRKGRPKDH--LPERQKYEKLCRGEGVKMTSRRQKRLFCRYFDGNKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRISKSAWLSAYEDPVVARLNRRIEGVTGLDMSTAEELQVANYGMGGQYEPHFDFARKDEPDAFKELGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLFESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCNLS 520          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSI-HVT-PENQNPETYINNPLKAYLLIQRLIRYW-KEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGEST-IKNPNLHSLKCRYY--VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            ++L LL        + FT++  +T   N++  L  +L ++    +  +  +K +   + H+T    ++PE Y+ +P+ A+ L++RL   W K E  IL    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +   SLT++ CF++G  ++ + DY++   W  +A  +++   +S  +K+ +LDYLS+  ++Q +L +AL LTK          R+ E         ++I +  S           +L     RP  H    E   YE LCRGE   + +     L CRY+        +L P K+E  + KPRIV YHD+I+D EI  +K L+  +LRRAT+ N ITG LE A YRI+KSAWL    + +  R+N RI+ VTG+++ TAEELQV NYGIGG YEPHFDF RK E ++F+    GNR+AT LFYMSDVEAGGATVF ++GA ++PKKG A FW+NLL SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    6 LVLPLLGLFSCAHADFFTSIGHMTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTATKDPEGYLGHPVNAFKLMKRLNTEWVKLENLILKDISDGF--ISNLTIQR-QYFPNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGEESSLDKVMVLDYLSYAVYQQGDLDKALTLTK----------RSLEG----NGNLRHIMSKESNKSSSSPSEGAELRTRKGRPKDH---LEKEKYEKLCRGEGVKMTSRRQKRLFCRYFDGKKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPVVARLNRRIEGVTGLDMSTAEELQVANYGIGGQYEPHFDFLRKYEPDAFKKLGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCNLS 517          

Query:  396 LTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSI-HVT-PENQNPETYINNPLKAYLLIQRLIRYW-KEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGEST-IKNPNLHSLKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            +T   N++  L  +L ++    +  +  +K +   + H+T    ++PE ++ +P+ A+ L++RL   W K E  IL    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +   SLT++ CF++G  ++ + DY++   W  +A  +++   +S  +K+ +LDYLS+  ++Q +L +AL LTK   ++DP + R + N  YF    + I +  S           +L     RP  H    E + YE LCRGE   + +     L CRY+  +     +L P K+E  + KPRIV YHD+I+D EI  +K L+  +LRRAT+ N ITG LE A YRISKSAWL    + +  R+N RI+ VTG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDVEAGGATVF ++GA ++PKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    8 MTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTATKDPEGFLGHPVNAFKLMKRLNTEWVKLENLILKDISDGF--ISNLTIQR-QYFPNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGEESSLDKVMVLDYLSYAVYQQGDLDKALTLTKLLLELDPEHQRGNGNLRYF----EYIMSKESNKSSSSPSEGAELGTRKGRPKDH--LPERQKYEKLCRGEGVKMTSRRQKRLFCRYFDGNKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRISKSAWLSAYEDPVVARLNRRIEGVTGLDMSTAEELQVANYGMGGQYEPHFDFARKDEPDAFKELGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLFESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCNLS 508          

Query:  330 VILFLLFFIP--LTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            V+L +   +P  L     FT++  +T   +++  L  +L ++    +  ++ +K + + +    +   ++PE ++ +P+ A+ L++RL   W E E  IL    + F  I+N   Q   Y PN +D  G+  AL RLQDTY + T+ I+ G +   +  + LT++ CFE+G  ++ E DY++   W  +A  ++ E   S  +K+ +LDYLS+  ++Q +L +AL LTK+  ++DP + RA+ N +YF       +++N    GD  D  T   A   +    D   E + YE LCRGE     P     L CRY+  +    F+L P K+E  + KPRI+ +HD+I+D EIE +K L+  +LRRAT+ N +TG LE  +YRISKSAWL    + +  RIN+RIQ +TG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    4 VVLMMAILLPQSLAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGF--ISNLTIQR-QYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEGELSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSDQKT---APKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531          

Query:  330 VILFLLFFIP--LTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            V+L +   +P  L     FT++  +T   +++  L  +L ++    +  ++ +K + + +    +   ++PE ++ +P+ A+ L++RL   W E E  IL    + F  I+N   Q   Y PN +D  G+  AL RLQDTY + T+ I+ G +   +  + LT++ CFE+G  ++ E DY++   W  +A  ++ E   S  +K+ +LDYLS+  ++Q +L +AL LTK+  ++DP + RA+ N +YF       +++N    GD  D  T   A   +    D   E + YE LCRGE     P     L CRY+  +    F+L P K+E  + KPRI+ +HD+I+D EIE +K L+  +L RATV +  TGKL  A YR+SKSAWL    + +  RIN+RIQ +TG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    4 VVLMMAILLPQSLAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGF--ISNLTIQR-QYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEGELSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSDQKT---APKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531          

Query:  363 TRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHV--TPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRIN--ENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYY----VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCA 1889
             + E FT++  +T    ++  L  +L E+    +A +  +K++   +    +    +PE Y+ +P+ AY L++RL   W      L+  D +   +AN   Q   + P  +D  G+  AL+RLQDTYK+    I+ G +   +    L+   CF +G  ++ E DY++ V W  +   +++  E     K  +LDYLS+  F+  +L +A+ LT+    +DP + RA  N  YF +  +  R  +   + D G        +  RP+  D   E   YE+LCRGE     P     L CRY+    VP    L+ P KEE  +  P IV Y+D+++D EIE IK ++  KL RATV++  TG L  A+YR+SKS+WL  D + +  R+N R+Q +TG+ ++TAE LQV NYG+GG YEPHFDF+R  E ++F+    GNR+AT L YMSDVEAGGATVF  +GA IWPKKG A FW+NLL SGEGD  TRHAACPVL+G KWV NKWFHERGQEF RPC 
Sbjct:   21 VQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEALTSRSAADPEGYLAHPVNAYKLVKRLNTDWPA-LGDLVLQDASAGFVANLSVQR-QFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAG--LATQENLYERPT--DYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQ--LLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCG 532          

Query:  363 TRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHV--TPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRIN--ENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYY----VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCA 1889
             + E FT++  +T    ++  L  +L E+    +A +  +K++   +    +    +PE Y+ +P+ AY L++RL   W      L+  D +   +AN   Q   + P  +D  G+  AL+RLQDTYK+    I+ G +   +    L+   CF +G  ++ E DY++ V W  +   +++  E     K  +LDYLS+  F+  +L +A+ LT+    +DP + RA  N  YF +  +  R  +   + D G        +  RP+  D   E   YE+LCRGE     P     L CRY+    VP    L+ P KEE  +  P IV Y+D+++D EIE IK ++  KL RATV++  TG L  A+YR+SKS+WL  D + +  R+N R+Q +TG+ ++TAE LQV NYG+GG YEPHFDF+R+   +  ++E GNRLAT L YMSDVEAGGATVF  +GA IWPKKG A FW+NLL SGEGD  TRHAACPVL+G KWV NKWFHERGQEF RPC 
Sbjct:   21 VQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEALTSRSAADPEGYLAHPVNAYKLVKRLNTDWPA-LGDLVLQDASAGFVANLSVQR-QFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAG--LATQENLYERPT--DYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQ--LLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTE-GNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCG 530          

Query:  363 TRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHV--TPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRIN--ENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYY----VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCA 1889
             + E FT++  +T    ++  L  +L E+    +A +  +K++   +    +    +PE Y+ +P+ AY L++RL   W      L+  D +   +AN   Q   + P  +D  G+  AL+RLQDTYK+    I+ G +   +    L+   CF +G  ++ E DY++ V W  +   +++  E     K  +LDYLS+  F+  +L +A+ LT+    +DP + RA  N  YF +  +  R  +   + D G        +  RP+  D   E   YE+LCRGE     P     L CRY+    VP    L+ P KEE  +  P IV Y+D+++D EIE IK ++  KL RATV++  TG L  A+YR+SKS+WL  D + +  R+N R+Q +TG+ ++TAE LQV NYG+GG YEPHFDF+R+   +  ++E GNRLAT L YMSDVEAGGATVF  +GA IWPKKG A FW+NLL SGEGD  TRHAACPVL+G KWV NKWFHERGQEF RPC 
Sbjct:   21 VQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEALTSRSAADPEGYLAHPVNAYKLVKRLNTDWPA-LGDLVLQDASAGFVANLSVQR-QFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAG--LATQENLYERPT--DYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQ--LLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTE-GNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCG 530          

Query:  372 EVFTALVDLTQSFNSKLQLG-NNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIG-LRSFEKDYFYFVEWASEAYYRINEN--VKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYF--TQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYV----PHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            + FT++  +T   N++  L  + L ++    ++ ++ +K + + +        ++PE ++ +P  A+ L++RL   W E    L+  D +   I+N   Q   + PN +D  G+  AL+RLQDTY + T  ++ G +   +  + LT++ CFE+G +R  E DY++   W  +A  +++E     ++K+ +LDYLS+  ++Q +L +A+ LTK   ++DP + RA+ N  YF     ++   N +S    D  D  T++   +  P       E R YE LCRGE     P     L CRYY     P Y  +LGP+K+E  + KPRIV + D+I+D EIE +K L+  +L RATV +  TGKL  A+YR+SKSAWL    + +  RIN RIQ +TG+++ TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL PSGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    3 DFFTSIGHMTDLINTEKDLVISKLKDYIKAEESKLEQIKKWAEKLDKLTDTATKDPEGFLGHPANAFKLMKRLNTEWGE-LESLVLKDMSDGFISNMTIQR-QFFPNDEDQTGARKALLRLQDTYNLDTDTLSRGNLPGVKHKSFLTAEDCFELGKIRYTEADYYHTELWMEQALKQLDEGEVSSADKVYILDYLSYAVYQQGDLSKAMMLTKRLLELDPEHQRANGNMKYFEYIMAKEKEANKSSTDAEDQTDKETEVKKKDYLP-------ERRKYEMLCRGEGLKMTPRRQKRLFCRYYDGNRNPRY--ILGPVKQEDEWDKPRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPVVSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 513          

Query:  330 VILFLLFFIP--LTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            V+L +   +P  L     FT++  +T   +++  L  +L ++    +  ++ +K + + +    +   ++PE ++ +P+ A+ L++RL   W E E  IL    + F  I+N   Q   Y PN +D  G+  AL RLQDTY + T+ I+ G +   +  + LT++ CFE+G  ++ E DY++   W  +A  ++ E   S  +K+ +LDYLS+  ++Q +L +AL LTK+  ++DP + RA+ N +YF       +++N    GD  D  T   A   +    D   E + YE LCRGE     P     L CRY+  +    F+L P K+E  + KPRI+ +HD+I+D EIE +K L+  +LRRAT+ N +TG LE  +YRISKSAWL    + +  RIN+RIQ +TG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    4 VVLMMAILLPQSLAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGF--ISNLTIQR-QYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEGELSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSDQKT---APKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531          

Query:  333 ILFLLFFIP--LTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDL----AAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            IL +   +P  L     FT++  +T   +++  L  +L ++    +  ++ +K + + +    +   ++PE ++ +P+ A+ L++RL   W E E  +L    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +  + LT + CFE+G  ++ E DY++   W  +A  +++E   S  +K+ +LDYLS+  ++Q +L +AL LTK+  ++DP + RA+ N  YF       +++N     D  D  T L    AA++  P       E + YE LCRGE     P     L CRY+  +    F+L P K+E  + KPRI+ +HD+I+D EIE +K L+  +LRRAT+ N ITG LE  +YRISKSAWL    N +  RIN+RIQ +TG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    5 ILVVGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGF--ISNLTIQR-QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGDLPGVKHKSFLTVEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEVSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDANKSSSDDQSDQKTTLKKKGAAVDYLP-------ERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEVVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVLAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKS-IH--VTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENF---DSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRI-NENVKS-EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNL-HSLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 1892
             +L +     L   ++FTA+ DL     ++  +   + ++    +A +  L+ +    +H     E+  PE ++ NP+ AYLLI+RL   WK+   I+++   +    +   NR++  + + P ++DL G+  AL+RLQDTY + T  ++NGII   + SN L+    FE+G  ++ +KDY++ + W   A  +I NEN  + E+ ++L+YL++  ++Q N+R+AL+LTK   KI P + RA  N  ++    Q              D+  DL  I  +   +D   E   YEALCRGE     P   + L+C       +  L P+K E L   P  V++ ++I+D+EIE IK L+  KL+RATVQNS TG+LE A YRISKSAWL+ D++ + +R+N RI+  T +N  T+EELQV NYG+GGHY+PHFDFARK E N+F++   GNR+AT+LFYMS  E GGATVF  +G  ++P K  A FW+NL   GEGDL TRHAACPVLLG KWV NKW HE+GQEFTRPC L
Sbjct:    3 AVLLVCLLAGLAHADLFTAIADLQHMLGAEKDVTTIIDQYIEAERARLDDLRRYAHEYVHRNAHAESVGPE-FVTNPINAYLLIKRLTTEWKKVENIMLNNKASTFLKNITDNRVRSEVKF-PGEEDLSGAATALLRLQDTYSLDTLDLSNGIIGGEKVSNKLSGHDTFEVGRSAYNQKDYYHCLMWMQVALVKIENENPPTIEEWEILEYLAYSLYQQGNVRRALSLTKRLAKIAPNHPRAKGNVKWYEDMLQG------------KDMVGDLPPIVNKRVEYDGIVERDAYEALCRGEIPPVEPKWKNKLRCYLKRDKPFLKLAPIKVEILRFDPLAVLFKNVIHDSEIEVIKELASPKLKRATVQNSKTGELEHATYRISKSAWLKGDLDPVIDRVNRRIEDFTNLNQATSEELQVANYGLGGHYDPHFDFARKEEKNAFKTLNTGNRIATVLFYMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVSNKWIHEKGQEFTRPCGL 520          

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            ++I+ +L    L     FT++  +T   +++  L  +L ++    +  ++ +K + + +    +   ++PE ++ +P+ A+ L++RL   W E E  +L    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY + T  I+ G +   +  + LT++ CFE+G  ++ E DY++   W  +A  +++E   S  +K+ +LDYLS+  ++Q +L +AL LTK+  ++DP + RA+ N  YF       ++ N     D  D  T      V     D   E + YE LCRGE     P     L CRY+  +    F+L P K+E  + KPRI+ +HD+I+D EIE +K L+  +LRRAT+ N ITG LE  +YRISKSAWL    N +  RIN+RIQ +TG+++ TAEELQV NYG+GG YEPHFDFARK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+
Sbjct:    5 ILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGF--ISNLTIQR-QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531          

Query:  327 MVILFLL--FFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPENQNPET----YINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNY-----LPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKSE-----KIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFT---DLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFL-LGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 1892
            + I F+L    I  T  EV+TAL ++ +   ++  L  NL  +    +  +  LK   K      E+++  T    Y++NP+ AYLL +RL   W++    L++ D   + + N    + NY      P+ +DL G+  AL+RLQDTYK+ T  +A G++   + S +++S  CFE+G +S+   DY++ V W +EA  R+ E   ++     +  +L+YL+F  +KQ N+  AL +T E  ++ P + RA  N++++ +E   ++ + S  KGD G   T   DL      PS +   NE ++YE LCRGE      +L  L+CRY   +  FL LGP+K E  F  P IVIYHD++ DNEI+ IK+++  + RRATVQNS+TG+LE ANYRISKSAWLRT+ +E+ E I  R + +TG+++  AEELQVVNYGIGGHYEPHFDFARK E+ +F+    GNR+AT+LFYMSDVE GGATVFT I   +WPKKG+AAFW+NL  SGEGD  TRHAACPVL GSKWV NKW HER QEF RPC L
Sbjct:   17 LSICFVLGTLTIRCTNSEVYTALAEMEELLETESVLITNLDGYLKVQQQKLDYLK--NKLGEYQREHEDAATDMPAYVSNPINAYLLTKRLTTDWRQ-VENLMAHDVGVEFLTN----ITNYRHVLKFPSDEDLNGAAVALMRLQDTYKLDTSSVARGMLNGIQYSTAMSSDDCFELGRQSYVNHDYYHTVLWMNEAMSRLQEEPTNQTQTFTRADILEYLAFSTYKQGNVESALTMTNELLELTPDHERARGNKVFYEKEIAELK-AESKVKGDDGSDSTPVSDLPISKGDPSVY-TFNERKSYEMLCRGELKPSPADLRPLRCRYVNNNVPFLRLGPLKLEEAFLDPYIVIYHDVMQDNEIDLIKKMARPRFRRATVQNSVTGELETANYRISKSAWLRTEEHEIIENIVQRTEDMTGLDMSVAEELQVVNYGIGGHYEPHFDFARKDEVRAFQGLNTGNRIATVLFYMSDVEQGGATVFTNIRIALWPKKGSAAFWYNLHKSGEGDYRTRHAACPVLTGSKWVSNKWIHERNQEFRRPCGL 551          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSI--HVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINE--NVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDR-GNEFRTYEALCRGESTIKNPNLHSLKCRYYV-PHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCA 1889
            + L L     +   E+FT++  L  +  ++  +   L ++    +  I+ LK+    +  H     + P+  I NP+ A+L ++RL   W+ E   +I+ D  + ++  +++ L   LP  +DL G+  AL+RLQDTYK+ T KIA G +    K  +L++  C+EIG  S+ E+D+++   W +EA  RI +  N    K  LLDYL+F  +KQ N+R AL+LT E   IDP + RA  N +Y+  E+       S  +GD G   +     N+R     R  +EF TYE+LCRGE+T    +   LKC Y    + + +L P KEE +   P IVIYHD+++D+EI  IK+L+  +L RATVQNS TG LE A YRISKSAWL+   + + +R+N RI+ +TG+  +TAEELQ+ NYG+GGHYEPHFDFAR+ E ++F+S   GNR+AT LFYMSDVEAGGATVF  IG K++PKKG AAFW+NL  +GEG  +TRHAACPVL+G+KWV NKW HERGQEF RPC 
Sbjct:    5 LALVLACVANMVESELFTSMAHLQTALYAERDIARTLKQYIESEEKRIEKLKSIANELADHSNRALEQPDKTIGNPVSAFLYVKRLTLDWEREIEPIINND-TYTTMVKQVEYLRQDLPKYEDLSGAAAALMRLQDTYKLDTSKIAEGDLG-GSKCATLSAVDCYEIGRISYNEEDFYHTTLWMNEAISRIQDEHNSTVSKSILLDYLAFAEYKQGNIRHALSLTNELLTIDPHHERAKNNRVYY--ERMIKEEEKSQKRGDEG---SKNVIHNIRKIDEYRNSDEFLTYESLCRGENTQVVKDADKLKCSYRTNKNGWLMLQPAKEEEVHLDPWIVIYHDVMSDDEINTIKQLATPRLNRATVQNSKTGALETAEYRISKSAWLKETDHPVVQRVNKRIEAITGLATDTAEELQIANYGLGGHYEPHFDFARREEKDAFKSLGTGNRIATFLFYMSDVEAGGATVFPYIGVKLFPKKGIAAFWYNLFKNGEGIYNTRHAACPVLVGTKWVSNKWLHERGQEFRRPCG 525          

Query:  333 ILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTP--ENQNPETYINNPLKAYLLIQRLIRYWK--EEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAA--INVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCR---YYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCA 1889
            +L L F +     E FTAL DL +  + + ++  +L ++    +A +  L      + V     +++PE Y+++P+ A+LL++RL+  W   EE       DE   +I++  +    + P  +DL G+++AL RLQDTYK+ +  IA G I     S +L +Q+CFE+G  ++   D ++ V W  EA  ++  N  S++  +LDYLS+  +   N+++AL LT     IDP +VR   N+ YF QE           +GD  D+  +     +      +D   E   YEALCRGE    +P     LKCR   Y  P  + +L P KEE +F KP+++I+HD I  NEI  +K L+  +LRRAT+QNS+TG LEFA YRISKSAWL  D  ++  R+N RI+  TG+ ++TAEELQV NYG+GGHYEPHFDFARK EIN+F+S   GNR+AT LFYMSDVEAGGATVF ++GA++ P+KG+AAFW+NLL +GEGD STRHAACPVL+GSKWV NKW HERGQEF   C 
Sbjct:   13 VLLLCFSVGCC--EFFTALSDLERLVHKESEMVQSLKQYILMEQAKLDELNRMASELEVMSLKASKDPEEYLHHPVNAFLLVKRLLSDWNTIEETVKYSHADEYVRNISDHQE----WFPGTEDLTGAVNALFRLQDTYKLDSSDIAEGRIIGATDSPTLNAQECFELGRVAYVAGDNYHTVIWMKEALRQLTTNNSSDEATILDYLSYSTYMIGNIKEALRLTNSLLAIDPEHVRGLGNKAYFEQELAKYNRQ----RGDDADVPGEEEKEFLESHKPLNDYLPEREAYEALCRGEQVKMSPQRQKKLKCRLRDYNRP--FLILQPAKEEVVFDKPKLIIFHDAILTNEIRKVKALASPRLRRATIQNSVTGNLEFAEYRISKSAWLSEDDGDVVHRLNHRIEQYTGLTMDTAEELQVANYGLGGHYEPHFDFARKEEINAFKSLNTGNRIATFLFYMSDVEAGGATVFPQVGARLIPEKGSAAFWYNLLKNGEGDYSTRHAACPVLVGSKWVSNKWIHERGQEFRHKCG 531          

Query:  327 MVILFLL--FFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPENQNPET----YINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNY-----LPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKSE-----KIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFT---DLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFL-LGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 1892
            + I F+L    I  T  EV+TAL ++ +   ++  L  +L  +    +  +  LK   K      E+++  T    Y++NP+ AYLL +RL   W++    L++ D   + + N    + NY      P+ +DL G+  AL+RLQDTYK+ T  +A G++   + S +++S  CFE+G +S+   DY++ V W +EA  R+ E   ++     +  +L+YL+F  +KQ N+  AL +T E  ++ P + RA  N++++ +E   ++ + S  KGD G   T   DL      PS +   NE ++YE LCRGE      +L  L+CRY   +  FL LGP+K E  +  P IVIYHD++ DNEIE IK+++  + RRATVQNS+TG+LE ANYRISKSAWLRT+ +E+ E I  R + +TG+++  AEELQVVNYGIGGHYEPHFDFARK E+ +F+    GNR+AT+LFYMSDVE GGATVFT I   +WPKKG+AAFW+NL  SGEGD  TRHAACPVL GSKWV NKW HER QEF RPC L
Sbjct:   18 LSICFVLCTLTIRCTNSEVYTALAEMEELLETESVLITSLDGYLKVQQQKLDYLK--NKLGEYQREHEDAATDMPAYVSNPINAYLLTKRLTTDWRQ-VENLMAHDVGVEFLTN----ITNYRHVLKFPSDEDLNGAAVALMRLQDTYKLDTSSVARGMLNGIQYSTAMSSDDCFELGRQSYVNHDYYHTVLWMNEAMTRLQEEPHNQTQTFTRADILEYLAFSTYKQGNVESALTMTNELLELTPDHERARGNKVFYEKEIAELK-AESKVKGDDGSDSTPVSDLPISKGDPSLYT-FNERKSYEMLCRGELKPSPADLRPLRCRYVNNNVPFLRLGPLKLEEAYLDPYIVIYHDVMRDNEIELIKKMARPRFRRATVQNSVTGELETANYRISKSAWLRTEEHEIIENIVQRTEDMTGLDMSVAEELQVVNYGIGGHYEPHFDFARKDEVRAFQGLNTGNRIATVLFYMSDVEQGGATVFTNIRIALWPKKGSAAFWYNLHKSGEGDYRTRHAACPVLTGSKWVSNKWIHERNQEFRRPCGL 552          

Query:  369 GEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPE--NQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNY-LPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFE-KDYFYFVEWASEAYYRINEN---VKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINV-----RPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFL-LGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRNAT 1907
             E++TAL D+ +   ++  L + L  +    +  + +L+   +      E  ++N + Y++NP+ AYLL++RL   WK     LI+ D     +AN      +   P  +DL G+  AL+RLQDTYK++T ++A G++   + S  LT+  CFE+G +S+  +DY++ V W  EA  R+ E      + K  +L+YL+F  + Q N+ +AL++T E  ++ P + RA  N  Y+ +E Q+  + +   +G+ G   T + A +      R  T D   E   YE LCRGE TI      +LKCRY      FL + P KEE  +  PRIV+YH++I D+EIE IKR++  + +RATVQN  TG LE ANYRISKSAWL+   ++    ++ R++ +T + ++TAEELQVVNYGIGGHYEPHFDFARK E N+F+S   GNR+AT+L+YMSDVE GG TVFT I   +WPKKG+AAFW+NL P+GEGD  TRHAACPVL GSKWV NKW HERGQEF RPC L    T
Sbjct:   31 AELYTALADMEELLETEAVLIDTLNGYIKAQEERLATLRKNVEDYAREHEEASRNIQQYLSNPINAYLLVKRLTTDWKR-VEELITQDVGKSFVANITSSRSDLKFPTDEDLNGAAVALMRLQDTYKLETAQVARGVLNGVQYSTGLTASDCFELGRQSYHNRDYYHTVLWMQEAMDRLQEEQNATTTSKPDILEYLAFSTYMQGNVARALSMTNELLELVPTHERALGNRAYYQKEIQSKASQSKKKRGEDGQDDTAVPAQHFTVAEERVKTLDEMTERERYEMLCRGEVTIPPEVQKNLKCRYVDRGIPFLKIAPFKEEEAYLDPRIVVYHNVIYDDEIETIKRMAQPRFKRATVQNYKTGALEIANYRISKSAWLQEHEHKHVAAVSRRVEHMTSMTVDTAEELQVVNYGIGGHYEPHFDFARKEETNAFKSLGTGNRIATVLYYMSDVEQGGGTVFTAINIALWPKKGSAAFWYNLKPNGEGDFKTRHAACPVLTGSKWVANKWLHERGQEFLRPCTLENQTT 556          

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGN----EFRTYEALCRGESTIKNPNLHS-LKCRYY----VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
            +V+L L         + FT++  +T    ++  L  +L ++    ++ +Q +K + + +    +   Q+PE ++ +P+ A+ L++RL   W + E  +L  T + F  I+N   Q   + P  +D  G+  AL+RLQDTY++ +  I+ G +      + +T + CFE+G  ++ + DY++   W ++A ++++E  +S  +K+ ++DYLS+  ++Q  + +AL LTK   K+DP + RA+ N  YF  + +  R +     G       +   ++ R     R      E + YE LCRGE     P   S L CRY      P    +L P+KEE  + +P IV +HD+I+D EI  +K L+  +LRRATV + ITGKL  A YR+SKSAWL  D + + ERIN RI+ +TG+ ++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVFT +GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+ N
Sbjct:    5 LVVLGLFLQTLHAHVDFFTSIGQMTDLLYTEKDLVTSLKDYIRAEESKLQEVKQWAEKLDSLTSTAVQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTDGF--ISNLTVQR-QHFPTDEDQTGAAKALLRLQDTYQLSSRAISAGDLPGVIHKSRMTVEDCFELGKIAYSDVDYYHTELWMTQALHQLDEGEESPIDKVTVMDYLSYAIYQQGEIDRALELTKRMLKLDPTHQRANGNLKYFEFQLEKQRKAEEE-AGKEAQKEGEKKHMDKRDVQMKRSKDPLPERKKYEQLCRGEGIKMTPRRWSRLFCRYQDNGRTPS--LILAPVKEEDEWDRPHIVRFHDIISDYEISKVKELAKPRLRRATVHDPITGKLTTAQYRVSKSAWLTADEHPVIERINQRIEDLTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRVATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGLSEN 539          

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGN----EFRTYEALCRGESTIKNPNLHS-LKCRYY----VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
            +V+L L         + FT++  +T    ++  L  +L ++    ++ +Q +K + + +    +   Q+PE ++ +P+ A+ L++RL   W + E  +L  T + F  I+N   Q   + P  +D  G+  AL+RLQDTY++ +  I+ G +      + +T + CFE+G  ++ + DY++   W ++A ++++E  +S  +K+ ++DYLS+  ++Q  + +AL LTK   K+DP + RA+ N  YF  + +  R +     G       +   ++ R     R      E + YE LCRGE     P   S L CRY      P    +L P+KEE  + +P IV +HD+I+D EI  +K L+  +LRRAT+ N ITG LE A YRISKSAWL  D + + ERIN RI+ +TG+ ++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVFT +GA +WPKKG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQEF RPC L+ N
Sbjct:    5 LVVLGLFLQTLHAHVDFFTSIGQMTDLLYTEKDLVTSLKDYIRAEESKLQEVKQWAEKLDSLTSTAVQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTDGF--ISNLTVQR-QHFPTDEDQTGAAKALLRLQDTYQLSSRAISAGDLPGVIHKSRMTVEDCFELGKIAYSDVDYYHTELWMTQALHQLDEGEESPIDKVTVMDYLSYAIYQQGEIDRALELTKRMLKLDPTHQRANGNLKYFEFQLEKQRKAEEE-AGKEAQKEGEKKHMDKRDVQMKRSKDPLPERKKYEQLCRGEGIKMTPRRWSRLFCRYQDNGRTPS--LILAPVKEEDEWDRPHIVRFHDIISDYEISKVKELAKPRLRRATISNPITGVLETAPYRISKSAWLTADEHPVIERINQRIEDLTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRVATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGLSEN 539          

Query:  264 CVCVPHNKCHIFQWQI*FN*TMVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANG----IITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEF----RTYEALCRGESTIKNPNLHS-LKCRYYV--PHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 1892
            C C  HN          F     +  LLF    T  ++ T+L D  ++  SKL+L           K   + L A T +       Q+PE ++ +P+ A+ L++RL   W E E  +L    + F  I+N   Q   Y PN +D  G+  AL+RLQDTY++ TH I++G    + +     ++LT   CFE+G  ++ + DY++   W  +A  ++++  +S  + + +LDYLS+  ++Q  L +AL  TK    +D  + RA+ N  YF  +    R +    KG              R       N F    R YE LCRGE     P   S L CR++    H Y++LGP+K+E  + +PRIV YH++I+D E+E +K LS  +LRRAT+ N ITG LE A+YRISKSAWL    + + +RIN RIQ +TG+++ TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVF ++GA I P KG A FW+NL PSGEGD STRHAACPVL+G+KWV NKW HERGQEF R C+L
Sbjct:   16 CKCSAHNDF--------FTSIGQMTDLLF----TEKDLVTSLKDYIKAEESKLEL----------VKQWAEKLDALTATA-----TQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGF--ISNLTIQR-QYFPNDEDQTGAAKALLRLQDTYRLDTHTISSGNLPGVTSDLPYKSTLTVDDCFELGKIAYSDADYYHTELWMGQALRQLDKGEESSIDSVTVLDYLSYSVYQQGELEKALEHTKRLLTLDSEHQRANGNLKYFEYQLAKQRKAEKEQKG----------TTEERTKRDTEKNSFLPEKRKYEKLCRGEGLRLTPRRQSRLFCRFHDNNRHPYYILGPVKQEDEWDRPRIVRYHNIISDKEMEKVKELSKPRLRRATISNPITGVLETAHYRISKSAWLAAYEHPVVDRINQRIQDITGLDVTTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAIKPMKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRRCSL 534          

Query:  369 GEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHV--TPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNS------LTSQQCFEIGLRSF-EKDYFYFVEWASEAYYR--INENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQE-QQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
             E+FT++  +T    ++ +L  +L E+    ++ + ++K +   + V       +PE ++ +P+ AY L++RL   W E    L+  D +   I+N I       P+++D  G+  AL+RLQDTY + +   + G +    + +       LT   CF++G  ++ E DY++ V W  +A  +    E  K  K ++LDYLS+  ++  +L +A+ LT+    IDP + RA  N  YF +   + +R  +        +    L     RP   D   E   YEALCRGE     P   S L CRY   +     LL PMKEE  +  P IV Y + ++D E+  IK L+  KL RATV++  TG L  A YR+SKSAWL  + + +  R+N RI+ VTG+ ++TAE LQV NYG+GG YEPHFDF+RK E ++F+S   GNR+AT L YMSDV+AGGATVF   GA IWP+KG A FW+NL  SGEGD  TRHAACPVL+GSKWV NKW HERGQEF RPC L 
Sbjct:   20 AEIFTSIGQMTDLLFTERELVQSLKEYIQAEESKLAAVKRWADKLEVLTRASTSDPEGFLAHPVNAYKLVKRLNTEWSE-LESLVLHDPSDGFISN-ISVHRQVFPDQEDENGAAKALMRLQDTYNLDSESFSKGKLPGQGQYSGVRYNAFLTVDDCFDMGKTAYNENDYYHAVLWMQQALRQKDAGEEAKVPKAEILDYLSYSVYQMGDLPRAIELTRRLVSIDPSHQRAGGNLRYFERLLSKELREMDQNRPEPTEEKPIQLGTYE-RP--RDYLPEREAYEALCRGEGIRMTPQRSSRLFCRYQDRNRNPRLLLKPMKEEDEWDSPHIVRYLEALSDEEMNRIKELAKPKLARATVRDPKTGVLTTAQYRVSKSAWLEDEDDLVIRRVNQRIEDVTGLTVDTAELLQVANYGVGGQYEPHFDFSRKDEPDAFKSLGTGNRVATYLNYMSDVDAGGATVFPDFGAAIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLIGSKWVSNKWIHERGQEFRRPCGLT 539          

Query:  330 VILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHV--TPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYR--INENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQE-QQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            +++F + ++PL  G+       +T    ++ +L  +L E+    ++ + ++K +   + V       +PE ++ +P+ AY L++RL   W E    L+  D +   I+N I       P+++D  G+  AL+RLQDTY + +   + G +     +  LT   CF++G  ++ E DY++ V W  +A  +    E  K  K ++LDYLS+  ++  +L +A+ LT+    IDP + RA  N  YF +   + +R  +        +    L     RP   D   E   YEALCRGE     P   S L CRY   +     LL PMKEE  +  P IV Y + ++D E+  IK L+  KL RATV++  TG L  A YR+SKSAWL  + + +  R+N RI+ VTG+ ++TAE LQV NYG+GG YEPHFDF+R                     MSDV+AGGATVF   GA IWP+KG A FW+NL  SGEGD  TRHAACPVL+GSKWV NKW HERGQEF RPC L 
Sbjct:   25 LLMFSITYLPLQLGQ-------MTDLLFTERELVQSLKEYIQAEESKLAAVKRWADKLEVLTRASTSDPEGFLAHPVNAYKLVKRLNTEWSE-LESLVLHDPSDGFISN-ISVHRQVFPDQEDENGAAKALMRLQDTYNLDSESFSKGKLPGVRYNAFLTVDDCFDMGKTAYNENDYYHAVLWMQQALRQKDAGEEAKVPKAEILDYLSYSVYQMGDLPRAIELTRRLVSIDPSHQRAGGNLRYFERLLSKELREMDQNRPEPTEEKPIQLGTYE-RP--RDYLPEREAYEALCRGEGIRMTPQRSSRLFCRYQDRNRNPRLLLKPMKEEDEWDSPHIVRYLEALSDEEMNRIKELAKPKLARATVRDPKTGVLTTAQYRVSKSAWLEDEDDLVIRRVNQRIEDVTGLTVDTAELLQVANYGVGGQYEPHFDFSR---------------------MSDVDAGGATVFPDFGAAIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLIGSKWVSNKWIHERGQEFRRPCGLT 522          

Query:  369 GEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAF--TKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTH-----KIANGIITRNEKSNSLTSQQCFEIGLRSFEKDYFYFVE-WASEAYYRINENVKSEKI----KLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQ-QNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHS-LKCRYYVP--HYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGI 1361
             EVFT++  +T     + +L ++L +   E +  +Q +K +   K         +PE ++ NP+ AY  + R+ + W      L  + E F    +R+ +     P+++D  G+  AL+RLQDTY +        K+  G+      +++L++  CF +G  ++ +  +   E W   A     E V  E       +LDYLS+  ++  ++++AL LT+    +DP + RA  N  YF  E  Q      +      GD       +       +  +E   YE LCR  S +  P     L CRY+    H   +L P+ EE  + +PRIV YH +++D EI  +
Sbjct:   23 AEVFTSIGHMTDLLYVEQELLSSLEKHIAEQELRLQRVKRWKEMKEAESHVATSDPEGFLGNPINAYHTM-RMGQRWAALENFLQESAEGF---VSRLAERRALFPSEEDRVGAARALLRLQDTYALDAELLASGKLPGGLCVPLVSASALSADDCFSLGRLAYSEGRYARAEPWLGHALS--QEGVGDEGTVGASDVLDYLSYSVYRLGDVQRALNLTRRLAVLDPDHPRAQANLHYFEYEMAQAAATEEATTDDAEGD-------VAAADDDEEYFSEKEEYELLCRSASGLMTPRRQRLLSCRYWDGRRHPLLILAPLMEEDEWDRPRIVRYHAIVSDEEIRHV 356          

Query:  504 HVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNE--KSNSLTSQQCFEIGLRSFEKDYFYFVE-WASEAYYRINENVKSEKI----KLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQE 1058
            HV     +PE ++ NP+ AY  + R+ + W      L  + E F S   R+ +     P+++D  G+  AL+RLQDTY +    +A+G +       +++L++  CF +G  ++ +  +   E W   A  +  E V  E       +LDYLS+  ++  ++++AL LT+    +DP + RA  N  YF  E
Sbjct:   44 HVA--TSDPEGFLGNPINAYHTM-RMGQRWAALENFLQESAEGFVS---RLAERRALFPSEEDRVGAARALLRLQDTYALDAELLASGKLPGVPLVSASALSADDCFSLGRLAYSEGRYARAEPWLGHALSQ--EGVGDEGTVGASDVLDYLSYSVYRLGDVQRALNLTRRLAVLDPDHPRAQANLHYFEYE 227          

Query:  537 YINNPLKAYLLIQRLIRYWK--EEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKSEKIKLLD---YLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQE--QQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGE-STIKNPNLHSLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKL----------------------RRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRNA 1904
            ++ +P+ ++ LI+R  + W   EE  +  +++   +++     Q     P+++D+ G+I AL+RLQDTY++    I+ G + +      +T    F+IG  ++   D FY   W   A  +I +   SE +KL D   +L+F  +++ N ++AL  ++E  KIDP + RA++N  YF  E  +Q  +  ++          +    +  R   H R   F+ YE LCRGE  ++       + C         +L P + E +F KP ++I+ + I D+EI+ IK L+  +L                      RRAT+Q+ +TGKLEFANYRISKS WLR + +EL +RI+ R+Q  +G+N+ T+E+LQVVNYGIGGHYEPH+DFAR  E        GNR+AT L Y+SDVEAGG TVFT++GA +WP+KG AAFW+NL  SG+GD STRHAACPVL+GSKWV NKW HE GQEF +PC+++RNA
Sbjct:   49 FLGHPVNSFALIKRFHKGWSRMEELALKDTSEVFVETLTKHKDQF----PSQEDVDGAITALLRLQDTYRLTPDVISTGRLPKVRAVPMMTVSDTFDIGRSAYLSNDMFYTKAWMEVALEKIKKGEDSEDVKLFDVYDHLAFAEYQRGNFKKALNYSEEMVKIDPTHTRATDNVAYFGSEIAKQTKKRGDTGTSRRTKSPSSTFKKLKEREYFH-RTKAFQNYEKLCRGEVRSLTKWEQGQMSCWQIRDDPLTVLKPGRIERVFVKPEVLIFRNFITDSEIKRIKELATPRLKRATVKDPVTGELIFANYRISKRRATIQHPVTGKLEFANYRISKSGWLRDEEDELVKRISYRVQAYSGLNMTTSEDLQVVNYGIGGHYEPHYDFARDGEDKFTSLGTGNRIATFLSYLSDVEAGGGTVFTRVGATVWPQKGDAAFWYNLKRSGDGDSSTRHAACPVLVGSKWVANKWIHEVGQEFRKPCSVDRNA 530          

Query:  324 TMVILFLLFFIP-LTRGEVFTALVDLTQSFNSKLQLGNNLLEFTN-------EAKAHIQSLKAFTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGL--RSFEKDYFYFVEWASEAYYRINENVKS----EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRY-YVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRT--DVNE--LTERINLRIQLVTGINL--ETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            ++++ FLL     L  GE+FTAL  +      +  L   L+E+ N       + +  ++ +K  TK+I       + E ++ +P+ AY+LI+R I+ WK+    L   D+  D +A      +++ P   D+ G + A+ R+QD Y I   +IA+G ++    +  +++  CFEIG     +EK +    +W  E+  R++   +     +K  +L+++++  +       ALA T E  ++DP N  A+ N  +F QE Q   N +           T    I  +P    R +    YE LCRG S   N     L+C Y +  H  F + P+K E L   P I +  D++ D+EIE IKR +  KLRRATV N  TG+LEFA+YRISKS WL    D NE  +  R+N R  ++TG++    +AE LQ+VNYG  GHYEPHFD A ++  +  +  IGNR+AT+L+YMSDVEAGGATVF    A + P KG AAFW+NL  +G+GD  TRHAACP+++GSKWV NKW HE GQEF RPC L+
Sbjct:    3 SVIVGFLLVCASTLACGELFTALTHMRGLIRLEKTLQRKLVEYLNLNPRASEDLRITMEEVKQHTKNI-----RGDVEKFLGHPVNAYMLIRRFIKNWKDVEEYLEKHDDQEDLLALLRLHKVDF-PTSKDMLGCVQAIQRIQDVYNITAKRIASGHLSDITSTPPMSADSCFEIGYAHHRWEK-HEEARQWMEESLRRLDPPFRYRGSLQKQDILEFIAWSEYMTEREDLALAHTSELLQLDPNNDFAARNLEFFLQEYQAKANGS-----------TKKPNIFKKPPP-PREHFMEAYERLCRGISYRSNEEAAKLRCYYDFTRHPMFRIRPLKVEELHSDPPIWMLRDVMYDSEIEYIKRTATPKLRRATVTNLKTGELEFADYRISKSGWLEDPRDDNEEKILNRVNRRTSIITGLDTTPRSAEALQIVNYGAAGHYEPHFDHATEAVSSILKLGIGNRIATVLYYMSDVEAGGATVFVDAEAIVKPSKGDAAFWYNLHKNGKGDERTRHAACPIIVGSKWVCNKWIHEHGQEFRRPCGLS 528          

Query:  369 GEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTK----SIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTS-QQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS-----EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRN-SNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFLLGPMKEETL----FHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRT-DVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
             EV++AL    +  + +L+L + L ++  E +  + ++K F      S+ ++ E  +P +YI +P+  YL+I+R +  W +   ++     +   + +R+    +  P  +DL G+I A+ RLQ+ Y +K    + G      K+  L   +  ++IG  S+ + D     EW +E    ++  V +      +  +LD+L+F  FK  + R+AL  T E  KIDP N RA  N  +FTQE +   N  N+  K ++   FT                     + + R ES               VP Y ++   + ++      +H  R  IY  L    ++          L RATV N ITG LE A+YRISK+ WL   +  E+ +R+  RI  +T +NLETAE  QV NYG+ G Y+PHFDF+R    +S  S   GNR+AT+L +MS VE+GGATVF  +GA+I P+KG A FW NLL SG+GD  TRHA CPVL G KWV NKW HE G EF RPC+L R+
Sbjct:    2 AEVYSALSHTQRIRDIELELNDALQDYIEEQETRLAAIKRFATEVKHSVDLSAEG-SPGSYIGHPVNMYLMIKRFVNEWPQVEKVVEEQSNSEAFLLDRLASSKSKFPTSEDLTGAITAIKRLQEVYALKPVDFSEGRFGFKPKTGYLLGPKDTYKIGRESYLDGDMVGTAEWMTETLRLMDLGVSNGAQAPRRTDVLDHLAFAEFKNGDGRKALNHTLELIKIDPENTRAKNNLAFFTQEMKRDENPENTRAKNNLA-FFT---------------------QEMKRDESKFTKKEEEKKN----VPSYKWMKSRLSQDVFENFNWHVERD-IYKRLCRGEKLP--------TLNRATVHNPITGHLETAHYRISKNCWLSGREHGEVIDRVERRIAAMTRLNLETAEGFQVQNYGLAGQYDPHFDFSRDLANSSLGSLGTGNRIATVLVWMSQVESGGATVFPYVGARILPQKGDAVFWHNLLRSGDGDFRTRHAGCPVLSGIKWVANKWIHEYGNEFHRPCSLRRD 494          

Query:  369 GEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAF--TKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWK--EEFPILISTDENFDSIANRIQQLLNY---LPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNS-LTSQQCFEIGLRSFEK-DYFYFVEW---------ASEAYYRINENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVR--PSTHDR----GN------EFRTYEALCRGESTIKNPNLH-SLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
             E+FT++  L +    +  L   L  +  + +  ++ LK     K   +    ++ E Y  +PL  + +I R+   W   E+          F      IQ++ NY    P+  D  G+  A++RLQ  Y I +  I++G+I     +++ L+    ++IG +++E  +      W          SE+   +  +V   +  +L++L+F  +K  +L ++L   +E    DP +          T+ Q NIR         +  L      +NV   P+T +R    G+      E   Y  LCR  S  + P+ +  L C Y   H    L P+  E +   P+I ++H+++++ EIE +  L+  +LRRA V N  TG++E  +YRIS+ AWL     ++  RIN R+  +TG+N  T E LQV NYG+GGHYEPHFD +   E +   S   GNR+AT +FY+S+VEAGG+TVF K G K  P KG A FW+NL  SGEGD  + HA CPVL+G+KWV NKW HE G EFTR C L  +
Sbjct:    8 AEIFTSMDQLQRLSTVEKNLHETLDLYIMQERKRLEDLKGIYAAKKEELKKRERDDEVY--HPLDVFRVINRVSSEWSTVEKLVRFNPHKSEF------IQEIRNYHASFPSDADFDGTRAAMLRLQKVYNISSQSISSGVIPGQRNAHARLSGIDSYQIGRKAYEDGNIIQAKAWMENTLRMMGTSESLQNLTGHVVVSRNDVLNHLAFLEYKIGDLARSLRFYREMLVNDPND----------TELQSNIRK--------LKHLIAKQPHLNVTSPPNTANRIEDDGDDELSREEMAEYTRLCRPNSQTRLPSSNKQLTCSYLNKHPGLKLKPVAMEIVSVNPQITLFHNVLSEMEIEQMLELARPRLRRARVNNLETGEIEDVDYRISQIAWLSDSDGDIVRRINRRVGFITGLNTNTGECLQVNNYGVGGHYEPHFDHSLDMENSPIASLGQGNRIATFMFYLSEVEAGGSTVFIKTGVKTNPFKGGAVFWYNLKKSGEGDWDSLHAGCPVLIGNKWVANKWLHEHGNEFTRQCGLTED 524          

Query: 1449 KSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPC 1886
            +S WLR + +EL +RI+ R+Q  +G+N+ T+E+LQVVNYGIGGHYEPH+DFAR    + F S   GNR+AT L Y+SDVEAGG TVFT++GA +WP+KG AAFW+NL  SG+GD STRHAACPVL+GSKWV NKW HE GQEF +PC
Sbjct:    2 RSGWLRDEEDELVKRISYRVQAYSGLNMTTSEDLQVVNYGIGGHYEPHYDFAR----DKFTSLGTGNRIATFLSYLSDVEAGGGTVFTRVGATVWPQKGDAAFWYNLKRSGDGDSSTRHAACPVLVGSKWVANKWIHEVGQEFLKPC 144          

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTP--ENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRIN--ENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQE-QQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGES-TIKNPNLHSLKCRYY----VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            + I ++L     T  EVFT++  +T    ++ +L  +L ++    ++ + ++K++   +         +PE Y+ +P+ AY L++RL   W E E  +L +  + F S  +  +Q   Y P+++D  G+  AL+RLQDTY++ +   + G++     +  LT   CF++G  ++ + DY++ V W  +A  +++  E     K  +LDYLS+  ++  +L +A+ LT+    IDP + RA  N  YF Q   + ++ SN  ++    +          RP  H    E  TYEALCRGE   +       L CRY+     P    LL P+KEE  +  P IV Y ++++D EIE IK L+  +L RATV++  TG L  A YR+SKSAWL  + + + +R+N RIQ +TG+ +ETAE LQV NYG+GG YEPHFDF+RK E ++F+    GNR+AT L YMSDVEAGGATVF   GA IWP+KG A FW+NL  SGEGD  TRHAACPVL+GSKWV NKW HERGQEF RPC L 
Sbjct:    5 VFISWVLVSCLRTHAEVFTSIGQMTDLLYTEKELVQSLRDYIKAEESKLAAVKSWANKLDALTRVSTSDPEGYLAHPVNAYKLMKRLNTEWSELESLVLQNPSDGFISNMSVHRQ---YFPDEEDQTGAAKALMRLQDTYQLDSEAFSKGMLPGVHSNAVLTVDDCFDMGKTAYNDADYYHAVLWFQQALKQLDDGEEAAVSKADILDYLSYSVYQMGDLPRAIELTRRLVAIDPNHQRAGGNLRYFEQLLMKQLKESNQDYQPPSEEPIQ--LGTYTRPKDH--LPERETYEALCRGEGLQLTEARRSRLFCRYHDGKRSPR--LLLKPIKEEDEWDNPHIVRYLNILSDQEIEKIKELAKPRLARATVRDPKTGVLTTAPYRVSKSAWLEGEDDPVIDRVNQRIQDITGLTVETAELLQVANYGVGGQYEPHFDFSRKDEPDAFKRLGTGNRMATFLNYMSDVEAGGATVFPDFGASIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWIHERGQEFRRPCGLT 531          

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTP--ENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRIN--ENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQE-QQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGES-TIKNPNLHSLKCRYY----VPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFES-EIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALN 1895
            + I ++L     T  EVFT++  +T    ++ +L  +L ++    ++ + ++K++   +         +PE Y+ +P+ AY L++RL   W E E  +L +  + F S  +  +Q   Y P+++D  G+  AL+RLQDTY++ +   + G++     +  LT   CF++G  ++ + DY++ V W  +A  +++  E     K  +LDYLS+  ++  +L +A+ LT+    IDP + RA  N  YF Q   + ++ SN  ++    +          RP  H    E  TYEALCRGE   +       L CRY+     P    LL P+KEE  +  P IV Y ++++D EIE IK L+  +L RATV++  TG L  A YR+SKSAWL  + + + +R+N RIQ +TG+ +ETAE LQV NYG+GG YEPHFDF+RK E ++F+    GNR+AT L YMSDVEAGGATVF   GA IWP+KG A FW+NL  SGEGD  TRHAACPVL+GSKWV NKW HERGQEF RPC L 
Sbjct:    5 VFISWVLVSCLRTHAEVFTSIGQMTDLLYTEKELVQSLRDYIKAEESKLAAVKSWANKLDALTRVSTSDPEGYLAHPVNAYKLMKRLNTEWSELESLVLQNPSDGFISNMSVHRQ---YFPDEEDQTGAAKALMRLQDTYQLDSEAFSKGMLPGVHSNAVLTVDDCFDMGKTAYNDADYYHAVLWFQQALKQLDDGEEAAVSKADILDYLSYSVYQMGDLPRAIELTRRLVAIDPNHQRAGGNLRYFEQLLMKQLKESNQDYQPPSEEPIQ--LGTYTRPKDH--LPERETYEALCRGEGLQLTEARRSRLFCRYHDGKRSPR--LLLKPIKEEDEWDNPHIVRYLNILSDQEIEKIKELAKPRLARATVRDPKTGVLTTAPYRVSKSAWLEGEDDPVIDRVNQRIQDITGLTVETAELLQVANYGVGGQYEPHFDFSRKDEPDAFKRLGTGNRMATFLNYMSDVEAGGATVFPDFGASIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWIHERGQEFRRPCGLT 531          

Query:  372 EVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYF-----TQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRG-NEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
            + FT++  +T    ++  L  +L ++    +  ++ +K +   +    +   Q+PE ++ +P+ A+ L++RL   W   E  +L  T + F  I+N   Q   Y P ++D  G+  AL+RLQDTY +  + I+ G +   +  N +T + C+E+G  ++ E DY++   W ++A  ++ E  +S  +K+ +LDYLS+  ++Q +L++AL  TK+  ++DP + RA+ N+ YF      QE+Q+        + D     T       +         E + YE LCRGE         S L CRYY   +   F+L P+K++  + +P IV Y D+I++ E++ IK+L+  +LRRAT+ N +TG LE A YRISKSAWL    + + E+IN RI+ +TG+ ++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVF  +GA + P+KG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQE+ RPC L+ N
Sbjct:   22 DFFTSIGQMTDLLYTEKDLVTSLKDYIRAEENKLEQVKRWADRLDSLTSTATQDPEGFLGHPVNAFKLMKRLNTEWGNLESLVLSDTTDGF--ISNLTIQR-QYFPTEEDQTGAAKALLRLQDTYNLDANTISTGDLPGVKHKNRMTVEDCYELGKVAYAEADYYHTELWMAQALRQLEEGEESPLDKVTVLDYLSYAIYQQGDLKRALEYTKKLLQLDPEHQRANGNQKYFEFQLEKQEKQDETAEKETQQQDREKRDTTQKKKKKQSQKSLSLIPERKKYEMLCRGEGVRMTSRRQSRLFCRYYDNKHNPRFVLAPVKQQDEWDRPYIVRYIDIISEAEMDKIKQLAKPRLRRATISNPVTGVLETAPYRISKSAWLTAYEDPVVEKINQRIEDLTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPDVGASVGPQKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEWRRPCGLSEN 544          

Query:  393 DLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYF-----TQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRG-NEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
            DL  S    ++   N LE        + SL         +   Q+PE ++ +P+ A+ L++RL   W   E  +L  T + F  I+N   Q   Y P ++D  G+  AL+RLQDTY +  + I+ G +   +  N +T + C+E+G  ++ E DY++   W ++A  ++ E  +S  +K+ +LDYLS+  ++Q +L++AL  TK+  ++DP + RA+ N+ YF      QE+Q+        + D     T       +         E + YE LCRGE         S L CRYY   +   F+L P+K++  + +P IV Y D+I++ E++ IK+L+  +LRRAT+ N +TG LE A YRISKSAWL    + + E+IN RI+ +TG+ ++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVF  +GA + P+KG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQE+ RPC L+ N
Sbjct:   10 DLVTSLKDYIRAEENKLEQVKRWADRLDSL--------TSTATQDPEGFLGHPVNAFKLMKRLNTEWGNLESLVLSDTTDGF--ISNLTIQR-QYFPTEEDQTGAAKALLRLQDTYNLDANTISTGDLPGVKHKNRMTVEDCYELGKVAYAEADYYHTELWMAQALRQLEEGEESPLDKVTVLDYLSYAIYQQGDLKRALEYTKKLLQLDPEHQRANGNQKYFEFQLEKQEKQDETAEKETQQQDREKRDTTQKKKKKQSQKSLSLIPERKKYEMLCRGEGVRMTSRRQSRLFCRYYDNKHNPRFVLAPVKQQDEWDRPYIVRYIDIISEAEMDKIKQLAKPRLRRATISNPVTGVLETAPYRISKSAWLTAYEDPVVEKINQRIEDLTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPDVGASVGPQKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEWRRPCGLSEN 515          

Query:  372 EVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIH--VTPENQNPETYINNPLKAYLLIQRLIRYWKE-EFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSF-EKDYFYFVEWASEAYYRINENVKS--EKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYF-----TQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRG-NEFRTYEALCRGESTIKNPNLHS-LKCRYYVPHY--YFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSF-ESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRN 1901
            + FT++  +T    ++  L  +L ++    +  ++ +K +   +    +   Q+PE ++ +P+ A+ L++RL   W   E  +L  T + F  I+N   Q   Y P ++D  G+  AL+RLQDTY +  + I+ G +   +  N +T + C+E+G  ++ E DY++   W ++A  ++ E  +S  +K+ +LDYLS+  ++Q +L++AL  TK+  ++DP + RA+ N+ YF      QE+Q+        + D     T       +         E + YE LCRGE         S L CRYY   +   F+L P+K++  + +P IV Y D+I++ E++ IK+L+  +LRRATV +  TGKL  A+YR+SKSAWL    + + E+IN RI+ +TG+ ++TAEELQV NYG+GG YEPHFDF RK E ++F E   GNR+AT LFYMSDV AGGATVF  +GA + P+KG A FW+NL  SGEGD STRHAACPVL+G+KWV NKW HERGQE+ RPC L+ N
Sbjct:   22 DFFTSIGQMTDLLYTEKDLVTSLKDYIRAEENKLEQVKRWADRLDSLTSTATQDPEGFLGHPVNAFKLMKRLNTEWGNLESLVLSDTTDGF--ISNLTIQR-QYFPTEEDQTGAAKALLRLQDTYNLDANTISTGDLPGVKHKNRMTVEDCYELGKVAYAEADYYHTELWMAQALRQLEEGEESPLDKVTVLDYLSYAIYQQGDLKRALEYTKKLLQLDPEHQRANGNQKYFEFQLEKQEKQDETAEKETQQQDREKRDTTQKKKKKQSQKSLSLIPERKKYEMLCRGEGVRMTSRRQSRLFCRYYDNKHNPRFVLAPVKQQDEWDRPYIVRYIDIISEAEMDKIKQLAKPRLRRATVHDPQTGKLTTAHYRVSKSAWLTAYEDPVVEKINQRIEDLTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPDVGASVGPQKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEWRRPCGLSEN 544          

Query:  327 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFTNEAKAHIQSLKAFTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFEKDYFYFVEWASEAYYRINENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRNATKSTLNRFVN 1934
            MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEF NEAKAHIQSLKAFTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFEKDYFYFVEWASEAYYRINENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFLLGP+KEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRNATKSTLNRFVN
Sbjct:    1 MVILFLLFFIPLTRGEVFTALVDLTQSFNSKLQLGNNLLEFANEAKAHIQSLKAFTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILISTDENFDSIANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFEKDYFYFVEWASEAYYRINENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFLLGPIKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCALNRNATKSTLNRFVN 536          

Query:  369 GEVFTALVDLTQSFNSKLQLG--------------NNLLEFTNEAKAHIQSLKAFTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILIS-TDENFDSI-ANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFEKDYFYF-VEWASEAY--YRIN----ENVKSEKIKLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIK-NPNLHSLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 1892
            GE+FTALVDL++ F ++  L               N L+EF  E K +  S   F+ S+ +       E Y +NP+ +YL  ++ +  WK++  ++    +  F  I    I +  + LPN DD+ G+IDA++RLQ+TY + T  +  G I   + +  L +  CF IG+ +++K+ F   V+W  E+   ++IN    +   +E+  +LDYLS+        R AL  T E  +    ++R            + ++N N + +  I +        N   S H  GN    Y ALCRGES I+ +    +LKC   +PH ++ +GP+K E  F KPR+VI HDLI+D EIE IK ++  KL RATV+N  TG LEFA+YRISKSAWL  D++E+T +IN RI   TG+N+E AE+LQVVNYGIGGHY PHFD  +K   ++FE E GNR+ATLLFYMSDVEAGGATVFT++GAK+WPKKG+AAFW+NL  +GE D  TRHA CPVL+GSKWVMNKWFHERGQEF RPC L
Sbjct:   21 GELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEI-------EKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNER-SILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIR-----------DRLLKNKNYYLEK-ISEEIVPNNDENPGFSDHYDGN---FYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVIIHDLIHDEEIEHIKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 529          

Query:  531 ETYINNPLKAYLLIQRLIRYWKEEFPIL--ISTD---------ENFDSIANR-IQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFEKDYFYFV-EWASEAYYRINENVKSEKIK---LLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIKNPNLHSLKCRYYVPHYYFLLGPMKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSI---TGKLEFANYRISKSAWLRTDVN-ELTERINLRIQLVTGIN---------LETAEELQVVNYGIGGHYEPHFDF------ARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPC 1886
            +T  N+P+ A   ++R++ +     PIL  I T          ++  S+ +R I++  +  P   DL+ ++  + R+ + YKI    I+ GII  +   N +   +   +   S  K+Y   V EWA          +K+   +   L+   +   F   N ++A+ L +E  +    + +  E ++ F +            K +   + T+   IN+  ++          + LCR      +   ++L+C Y      +     K E L   P I  Y+ ++ND +I  +     N ++ + ++  +    G L  AN + +K   +  D + ++ + ++ +I   TG+          + ++   +V+NYGIGG+ E   D+       +K +++ F    G+RLAT  ++++D   GG  VF K+   +  ++G    W+NLL +G  +  + H  CPV  GSKWV+ K+ HE G  FTR C
Sbjct:  112 KTPTNHPINALHFMRRIVFHLN---PILNRIFTSKTLLKRNFYQDLSSVLDRYIREECSCWPTPSDLQVAVSGIARIINVYKIPKANISKGIIFNHTSINPMLLDEMIVLAQESNRKNYHSDVLEWAEFLLNNFESEIKNNDNQFRNLVRMKAAALFNTKNEKEAINLLEEIIREKLFDNKLLERDLKFYKS-----------KSEQDKVNTENQNINLSNNS----------DLLCR--ENYNSSEYYNLRCFYRRIKKGW--DRAKVELLNMNPPIYKYYGVLNDEDIYEV----FNLVKTSKIKQHVYLEKGVLN-ANEKYAKEEAIFWDEDYDVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAKVDEEKKKDVSVFG---GDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 562