C2 NT-type domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30034396 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of C2 NT-type domain-containing protein vs. Ensembl Human
Match: FAM102B (family with sequence similarity 102 member B [Source:HGNC Symbol;Acc:HGNC:27637]) HSP 1 Score: 140.969 bits (354), Expect = 7.445e-37 Identity = 70/153 (45.75%), Postives = 103/153 (67.32%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVP 613 V LEELSS+PFVNG+LF KMRLLD + SSRE ++ + V W F C++ A+ T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ ++ + GDPCF+ P TS +P Sbjct: 11 VDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRWRKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTT--RRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTP-PSTSMSIP 160
BLAST of C2 NT-type domain-containing protein vs. Ensembl Human
Match: FAM102B (family with sequence similarity 102 member B [Source:HGNC Symbol;Acc:HGNC:27637]) HSP 1 Score: 140.584 bits (353), Expect = 1.010e-36 Identity = 70/153 (45.75%), Postives = 103/153 (67.32%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVP 613 V LEELSS+PFVNG+LF KMRLLD + SSRE ++ + V W F C++ A+ T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ ++ + GDPCF+ P TS +P Sbjct: 11 VDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRWRKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTT--RRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTP-PSTSMSIP 160
BLAST of C2 NT-type domain-containing protein vs. Ensembl Human
Match: FAM102A (family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419]) HSP 1 Score: 132.88 bits (333), Expect = 1.032e-33 Identity = 64/140 (45.71%), Postives = 95/140 (67.86%), Query Frame = 2 Query: 170 LEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G T R +LEGY+ ++ RQDNS+L++ + L GDPCF+ P Sbjct: 18 LEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCVFRVSVRKELKGGKAYSKLGFADLNLAEFAGSGSTV--RCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Celegans
Match: sym-3 (SYM-3B [Source:UniProtKB/TrEMBL;Acc:G5EE38]) HSP 1 Score: 115.546 bits (288), Expect = 1.264e-28 Identity = 56/150 (37.33%), Postives = 90/150 (60.00%), Query Frame = 2 Query: 137 KKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 +K+ +F V L + +LS +P VN +F KMRLLD + ++ + R +KNH ++N+ F CR+ + + LE ++S+RKE KGGKS+ K+G+V +N++ +A G R Y+L GY ++R DNS + + + DP FRVP Sbjct: 6 RKTVKFSVDLQVCQLSDVPLVNATVFGKMRLLDGGSFEEATERVEVKNHSASFNTRFVFCCRIPCDQTSGTLEKCLCRVSIRKEQKGGKSYYKLGFVDINLSEYAASGVEGISRTYLLNGYTSNQRLDNSKVCIKVAMTHQSADPFFRVP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Celegans
Match: sym-3 (SYM-3B [Source:UniProtKB/TrEMBL;Acc:G5EE38]) HSP 1 Score: 110.153 bits (274), Expect = 3.290e-28 Identity = 55/149 (36.91%), Postives = 89/149 (59.73%), Query Frame = 2 Query: 137 KKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRV 583 +K+ +F V L + +LS +P VN +F KMRLLD + ++ + R +KNH ++N+ F CR+ + + LE ++S+RKE KGGKS+ K+G+V +N++ +A G R Y+L GY ++R DNS + + + DP FRV Sbjct: 6 RKTVKFSVDLQVCQLSDVPLVNATVFGKMRLLDGGSFEEATERVEVKNHSASFNTRFVFCCRIPCDQTSGTLEKCLCRVSIRKEQKGGKSYYKLGFVDINLSEYAASGVEGISRTYLLNGYTSNQRLDNSKVCIKVAMTHQSADPFFRV 154
BLAST of C2 NT-type domain-containing protein vs. Ensembl Fly
Match: CG8671 (gene:FBgn0032938 transcript:FBtr0081484) HSP 1 Score: 143.665 bits (361), Expect = 2.807e-37 Identity = 65/145 (44.83%), Postives = 101/145 (69.66%), Query Frame = 2 Query: 152 FEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 F V + L++L + VN +LFAK+RLLD + ++YSSRE ++NH V WN + +F C++ AN T +L+P ++IS+RKE+KGG+S+ K+G++ +N+A FA G T+ RR++LEGY+ R DNSML++ + L GD F+ P Sbjct: 22 FNVEVQLQDLVEVALVNEVLFAKIRLLDGGSFQEYSSREEVRNHRVEWNRSFEFPCKMSANASTGVLDPCHLRISIRKEMKGGRSYYKLGFIDLNLAEFAGAGLTS--RRFLLEGYDSRHRLDNSMLRVSIKMHMLSGDILFKAP 164
BLAST of C2 NT-type domain-containing protein vs. Ensembl Fly
Match: CG8671 (gene:FBgn0032938 transcript:FBtr0330678) HSP 1 Score: 143.665 bits (361), Expect = 2.352e-36 Identity = 65/145 (44.83%), Postives = 101/145 (69.66%), Query Frame = 2 Query: 152 FEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 F V + L++L + VN +LFAK+RLLD + ++YSSRE ++NH V WN + +F C++ AN T +L+P ++IS+RKE+KGG+S+ K+G++ +N+A FA G T+ RR++LEGY+ R DNSML++ + L GD F+ P Sbjct: 22 FNVEVQLQDLVEVALVNEVLFAKIRLLDGGSFQEYSSREEVRNHRVEWNRSFEFPCKMSANASTGVLDPCHLRISIRKEMKGGRSYYKLGFIDLNLAEFAGAGLTS--RRFLLEGYDSRHRLDNSMLRVSIKMHMLSGDILFKAP 164
BLAST of C2 NT-type domain-containing protein vs. Ensembl Fly
Match: CG8671 (gene:FBgn0032938 transcript:FBtr0330680) HSP 1 Score: 143.665 bits (361), Expect = 3.813e-36 Identity = 65/145 (44.83%), Postives = 101/145 (69.66%), Query Frame = 2 Query: 152 FEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 F V + L++L + VN +LFAK+RLLD + ++YSSRE ++NH V WN + +F C++ AN T +L+P ++IS+RKE+KGG+S+ K+G++ +N+A FA G T+ RR++LEGY+ R DNSML++ + L GD F+ P Sbjct: 22 FNVEVQLQDLVEVALVNEVLFAKIRLLDGGSFQEYSSREEVRNHRVEWNRSFEFPCKMSANASTGVLDPCHLRISIRKEMKGGRSYYKLGFIDLNLAEFAGAGLTS--RRFLLEGYDSRHRLDNSMLRVSIKMHMLSGDILFKAP 164
BLAST of C2 NT-type domain-containing protein vs. Ensembl Fly
Match: CG8671 (gene:FBgn0032938 transcript:FBtr0114602) HSP 1 Score: 143.665 bits (361), Expect = 3.845e-36 Identity = 65/145 (44.83%), Postives = 101/145 (69.66%), Query Frame = 2 Query: 152 FEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 F V + L++L + VN +LFAK+RLLD + ++YSSRE ++NH V WN + +F C++ AN T +L+P ++IS+RKE+KGG+S+ K+G++ +N+A FA G T+ RR++LEGY+ R DNSML++ + L GD F+ P Sbjct: 22 FNVEVQLQDLVEVALVNEVLFAKIRLLDGGSFQEYSSREEVRNHRVEWNRSFEFPCKMSANASTGVLDPCHLRISIRKEMKGGRSYYKLGFIDLNLAEFAGAGLTS--RRFLLEGYDSRHRLDNSMLRVSIKMHMLSGDILFKAP 164
BLAST of C2 NT-type domain-containing protein vs. Ensembl Fly
Match: CG8671 (gene:FBgn0032938 transcript:FBtr0330679) HSP 1 Score: 143.665 bits (361), Expect = 4.046e-36 Identity = 65/145 (44.83%), Postives = 101/145 (69.66%), Query Frame = 2 Query: 152 FEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 F V + L++L + VN +LFAK+RLLD + ++YSSRE ++NH V WN + +F C++ AN T +L+P ++IS+RKE+KGG+S+ K+G++ +N+A FA G T+ RR++LEGY+ R DNSML++ + L GD F+ P Sbjct: 22 FNVEVQLQDLVEVALVNEVLFAKIRLLDGGSFQEYSSREEVRNHRVEWNRSFEFPCKMSANASTGVLDPCHLRISIRKEMKGGRSYYKLGFIDLNLAEFAGAGLTS--RRFLLEGYDSRHRLDNSMLRVSIKMHMLSGDILFKAP 164
BLAST of C2 NT-type domain-containing protein vs. Ensembl Zebrafish
Match: fam102ba (family with sequence similarity 102 member Ba [Source:ZFIN;Acc:ZDB-GENE-060616-312]) HSP 1 Score: 138.272 bits (347), Expect = 4.119e-36 Identity = 69/144 (47.92%), Postives = 100/144 (69.44%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 V + LEELSS+P+VNG+LF K+RL D S++ SSREP+ + V W F C++ AN T +L+P ++SVRKE+KGGK+F K+G+ +N+A FA G T RR +LEGYN ++ RQDNS+L++ ++ + GDPCF+ P Sbjct: 15 VDVELEELSSVPYVNGVLFCKVRLTDGGFSEE-SSREPVLVNCVKWKKRFSFICKMSANAGTGVLDPCVFRVSVRKELKGGKTFAKLGFADLNLAEFAGSGSTT--RRCLLEGYNTKNTRQDNSILKVIISMHLMSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Zebrafish
Match: fam102ba (family with sequence similarity 102 member Ba [Source:ZFIN;Acc:ZDB-GENE-060616-312]) HSP 1 Score: 138.272 bits (347), Expect = 5.977e-36 Identity = 69/144 (47.92%), Postives = 100/144 (69.44%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 V + LEELSS+P+VNG+LF K+RL D S++ SSREP+ + V W F C++ AN T +L+P ++SVRKE+KGGK+F K+G+ +N+A FA G T RR +LEGYN ++ RQDNS+L++ ++ + GDPCF+ P Sbjct: 15 VDVELEELSSVPYVNGVLFCKVRLTDGGFSEE-SSREPVLVNCVKWKKRFSFICKMSANAGTGVLDPCVFRVSVRKELKGGKTFAKLGFADLNLAEFAGSGSTT--RRCLLEGYNTKNTRQDNSILKVIISMHLMSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Zebrafish
Match: fam102aa (family with sequence similarity 102 member Aa [Source:ZFIN;Acc:ZDB-GENE-081104-233]) HSP 1 Score: 136.732 bits (343), Expect = 3.348e-35 Identity = 68/148 (45.95%), Postives = 100/148 (67.57%), Query Frame = 2 Query: 170 LEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCV 610 LEEL+++PFVNG+LF K+RLLD + SSRE + + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G TA R +LEGY+ ++ RQDNS+L++ + L GDPCF+ P T+KC+ Sbjct: 18 LEELTAVPFVNGVLFCKIRLLDGGDFTASSSREEVHQNCVRWRKRFSFVCKMSANSNTGVLDPCMCRVSVRKELKGGKAYSKLGFADLNMAEFAGSGWTA--RCCLLEGYDTKNTRQDNSILKVTIGMTLLSGDPCFKTP-PSTAKCI 162
BLAST of C2 NT-type domain-containing protein vs. Ensembl Zebrafish
Match: fam102aa (family with sequence similarity 102 member Aa [Source:ZFIN;Acc:ZDB-GENE-081104-233]) HSP 1 Score: 135.961 bits (341), Expect = 4.660e-35 Identity = 68/148 (45.95%), Postives = 100/148 (67.57%), Query Frame = 2 Query: 170 LEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCV 610 LEEL+++PFVNG+LF K+RLLD + SSRE + + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G TA R +LEGY+ ++ RQDNS+L++ + L GDPCF+ P T+KC+ Sbjct: 18 LEELTAVPFVNGVLFCKIRLLDGGDFTASSSREEVHQNCVRWRKRFSFVCKMSANSNTGVLDPCMCRVSVRKELKGGKAYSKLGFADLNMAEFAGSGWTA--RCCLLEGYDTKNTRQDNSILKVTIGMTLLSGDPCFKTP-PSTAKCI 162
BLAST of C2 NT-type domain-containing protein vs. Ensembl Zebrafish
Match: fam102bb (family with sequence similarity 102 member Bb [Source:ZFIN;Acc:ZDB-GENE-041014-330]) HSP 1 Score: 135.576 bits (340), Expect = 5.296e-35 Identity = 67/144 (46.53%), Postives = 99/144 (68.75%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 V L+ELSS+PFVNG+LF K+RLLD S++ SSRE ++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G T RR +LEGY+ ++ RQDNS+L++ + + GDPCF+ P Sbjct: 11 VDFELDELSSVPFVNGVLFCKVRLLDGGFSEE-SSRETVQANCVHWRKRFSFPCKMSANAGTGVLDPCVCRVSVRKELKGGKTYAKLGFADLNLAEFAGSGSTT--RRCLLEGYDTKNTRQDNSILKVIISTQLMSGDPCFKTP 151
BLAST of C2 NT-type domain-containing protein vs. Ensembl Xenopus
Match: spi1 (Spi-1 proto-oncogene [Source:Xenbase;Acc:XB-GENE-1018247]) HSP 1 Score: 134.806 bits (338), Expect = 1.569e-34 Identity = 68/154 (44.16%), Postives = 102/154 (66.23%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFR-VPDEDTSKCVP 613 V L+ LSS+PFVNGILF K+RLLD N SSRE ++ + V W F C++ A+ + +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ ++ + GDPCF+ P TS +P Sbjct: 15 VDFELDNLSSVPFVNGILFCKIRLLDGGNFSVESSREVVQANSVHWRKQFTFVCKMSASANSGILDPCVCRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTI--RRCLLEGYDTKNTRQDNSILKVGISMQLMSGDPCFKTAPSTATSIAIP 166
BLAST of C2 NT-type domain-containing protein vs. Ensembl Xenopus
Match: fam102a (family with sequence similarity 102 member A [Source:NCBI gene;Acc:100036602]) HSP 1 Score: 134.42 bits (337), Expect = 2.472e-34 Identity = 65/145 (44.83%), Postives = 98/145 (67.59%), Query Frame = 2 Query: 155 EVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 + + LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G TA R +LEGY+ ++ RQDNS+L++ + L GDPCF+ P Sbjct: 13 QTSFNLEELTAVPFVNGVLFCKVRLLDGGDFVSQSSREEVQENCVHWRKKFNFVCKMSANPATGVLDPCVCRVSVRKELKGGKTYSKLGFADLNLAEFAGSGSTA--RCCLLEGYDTRNTRQDNSILKVIIGMSLLSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Xenopus
Match: fam102a (family with sequence similarity 102 member A [Source:NCBI gene;Acc:100036602]) HSP 1 Score: 115.161 bits (287), Expect = 1.263e-27 Identity = 61/145 (42.07%), Postives = 92/145 (63.45%), Query Frame = 2 Query: 155 EVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 + + LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F C++ AN T +L+P ++SVRK K + +L G+ +N+A FA G TA R +LEGY+ ++ RQDNS+L++ + L GDPCF+ P Sbjct: 13 QTSFNLEELTAVPFVNGVLFCKVRLLDGGDFVSQSSREEVQENCVHWRKKFNFVCKMSANPATGVLDPCVCRVSVRKVRKINRRWL--GFADLNLAEFAGSGSTA--RCCLLEGYDTRNTRQDNSILKVIIGMSLLSGDPCFKTP 153
BLAST of C2 NT-type domain-containing protein vs. Ensembl Xenopus
Match: spi1 (Spi-1 proto-oncogene [Source:Xenbase;Acc:XB-GENE-1018247]) HSP 1 Score: 96.2857 bits (238), Expect = 1.987e-21 Identity = 48/126 (38.10%), Postives = 80/126 (63.49%), Query Frame = 2 Query: 266 EPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFR-VPDEDTSKCVPYEVFSQNK 637 E ++ + V W F C++ A+ + +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ ++ + GDPCF+ P TS +P + S K Sbjct: 17 EVVQANSVHWRKQFTFVCKMSASANSGILDPCVCRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTI--RRCLLEGYDTKNTRQDNSILKVGISMQLMSGDPCFKTAPSTATSIAIPGDSDSLQK 140
BLAST of C2 NT-type domain-containing protein vs. Ensembl Mouse
Match: Fam102b (family with sequence similarity 102, member B [Source:MGI Symbol;Acc:MGI:3036259]) HSP 1 Score: 140.198 bits (352), Expect = 1.255e-36 Identity = 70/153 (45.75%), Postives = 103/153 (67.32%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVP 613 V LEELSS+PFVNG+LF KMRLLD + SSRE ++ + V W F C++ A+ T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ ++ + GDPCF+ P TS +P Sbjct: 11 VDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVHWRKKFSFMCKMSASASTGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTT--RRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTP-PSTSMSIP 160
BLAST of C2 NT-type domain-containing protein vs. Ensembl Mouse
Match: Fam102a (family with sequence similarity 102, member A [Source:MGI Symbol;Acc:MGI:2138935]) HSP 1 Score: 132.494 bits (332), Expect = 1.393e-33 Identity = 64/140 (45.71%), Postives = 95/140 (67.86%), Query Frame = 2 Query: 170 LEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G T R +LEGY+ ++ RQDNS+L++ + L GDPCF+ P Sbjct: 18 LEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCIFRVSVRKELKGGKAYSKLGFTDLNLAEFAGSGSTV--RCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Mouse
Match: Fam102b (family with sequence similarity 102, member B [Source:MGI Symbol;Acc:MGI:3036259]) HSP 1 Score: 110.538 bits (275), Expect = 2.810e-26 Identity = 55/132 (41.67%), Postives = 86/132 (65.15%), Query Frame = 2 Query: 221 MRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVP 613 MRLLD + SSRE ++ + V W F C++ A+ T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ ++ + GDPCF+ P TS +P Sbjct: 1 MRLLDGGSFTAESSREVVQANCVHWRKKFSFMCKMSASASTGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTT--RRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTP-PSTSMSIP 129
BLAST of C2 NT-type domain-containing protein vs. Ensembl Mouse
Match: Fam102a (family with sequence similarity 102, member A [Source:MGI Symbol;Acc:MGI:2138935]) HSP 1 Score: 59.3066 bits (142), Expect = 6.698e-11 Identity = 26/55 (47.27%), Postives = 37/55 (67.27%), Query Frame = 2 Query: 170 LEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVAN 334 LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F C++ AN Sbjct: 18 LEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSAN 72
BLAST of C2 NT-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5T8I3|F102B_HUMAN (Protein FAM102B OS=Homo sapiens OX=9606 GN=FAM102B PE=1 SV=2) HSP 1 Score: 140.584 bits (353), Expect = 4.849e-36 Identity = 70/153 (45.75%), Postives = 103/153 (67.32%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVP 613 V LEELSS+PFVNG+LF KMRLLD + SSRE ++ + V W F C++ A+ T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ ++ + GDPCF+ P TS +P Sbjct: 11 VDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRWRKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTT--RRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTP-PSTSMSIP 160
BLAST of C2 NT-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6GNM6|F102A_XENLA (Protein FAM102A OS=Xenopus laevis OX=8355 GN=fam102a PE=2 SV=1) HSP 1 Score: 134.035 bits (336), Expect = 1.766e-33 Identity = 64/145 (44.14%), Postives = 98/145 (67.59%), Query Frame = 2 Query: 155 EVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 + + LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G A R +LEGY+ ++ RQDNS+L+++ + L GDPCF+ P Sbjct: 13 QTSFNLEELTAVPFVNGVLFCKVRLLDGGDFVSQSSREEVQENCVRWKKKFNFVCKMSANSATGVLDPCVCRVSVRKELKGGKTYSKLGFADLNLAEFAGSGSAA--RCCLLEGYDTRNTRQDNSILKVNIGMSLLSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5T9C2|F102A_HUMAN (Protein FAM102A OS=Homo sapiens OX=9606 GN=FAM102A PE=1 SV=2) HSP 1 Score: 132.88 bits (333), Expect = 4.954e-33 Identity = 64/140 (45.71%), Postives = 95/140 (67.86%), Query Frame = 2 Query: 170 LEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G T R +LEGY+ ++ RQDNS+L++ + L GDPCF+ P Sbjct: 18 LEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCVFRVSVRKELKGGKAYSKLGFADLNLAEFAGSGSTV--RCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q78T81|F102A_MOUSE (Protein FAM102A OS=Mus musculus OX=10090 GN=Fam102a PE=1 SV=1) HSP 1 Score: 132.494 bits (332), Expect = 9.741e-33 Identity = 64/140 (45.71%), Postives = 95/140 (67.86%), Query Frame = 2 Query: 170 LEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G T R +LEGY+ ++ RQDNS+L++ + L GDPCF+ P Sbjct: 18 LEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCIFRVSVRKELKGGKAYSKLGFTDLNLAEFAGSGSTV--RCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8BQS4|F102B_MOUSE (Protein FAM102B OS=Mus musculus OX=10090 GN=Fam102b PE=2 SV=2) HSP 1 Score: 110.538 bits (275), Expect = 1.965e-25 Identity = 55/132 (41.67%), Postives = 86/132 (65.15%), Query Frame = 2 Query: 221 MRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVP 613 MRLLD + SSRE ++ + V W F C++ A+ T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ ++ + GDPCF+ P TS +P Sbjct: 1 MRLLDGGSFTAESSREVVQANCVHWRKKFSFMCKMSASASTGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTT--RRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTP-PSTSMSIP 129
BLAST of C2 NT-type domain-containing protein vs. TrEMBL
Match: A0A5J4P0X9 (C2 NT-type domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0002162 PE=4 SV=1) HSP 1 Score: 204.527 bits (519), Expect = 8.078e-55 Identity = 101/205 (49.27%), Postives = 136/205 (66.34%), Query Frame = 2 Query: 116 MLCVP--TGKKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQD-KRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVPYEVFSQNKLLIVTPNS--SLEGIDGLLDSEPIDSEG 715 M CVP +K YQFE + L L S+P+VN + FAK+RLL++R+S QYS R I+NH VTWN+ H+F CR +N++T +LEP+ +KIS+R E KGGKSF K+G+V V++ACF LGD RRRYILEGYN+ KR DNS+L + F++ QLFGD CFR P E+ C LI P+S S + G + ++P D+ G Sbjct: 1 MACVPILNRRKGYQFEAVVKLHSLISVPYVNAVTFAKLRLLNARHSSQYSPRVEIRNHTVTWNTEHRFLCRFRSNMETTILEPNVLKISIRMETKGGKSFYKVGFVSVDLACFTALGDVTSRRRYILEGYNEKHKRLDNSLLLVSFSMRQLFGDTCFRAPPENLRNC-----------LIEPPDSDESDSALTGTVVTDPPDAMG 194
BLAST of C2 NT-type domain-containing protein vs. TrEMBL
Match: A0A504YQP9 (C2 NT-type domain-containing protein OS=Fasciola gigantica OX=46835 GN=FGIG_05903 PE=4 SV=1) HSP 1 Score: 201.83 bits (512), Expect = 1.096e-53 Identity = 88/168 (52.38%), Postives = 124/168 (73.81%), Query Frame = 2 Query: 116 MLCVP--TGKKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQD-KRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCV 610 M C P + +K Y FEV + L L ++P+VN + FAK+RLLD+R++ QYS+R I+NH V+WN+ H+F C+ +N TN+LEP +KIS+R E KGGKSF K+G+V++N+A FA +G CRRRYIL GY++ KRQDNS+L + F++ QLFGD CFR+P E+ S C+ Sbjct: 1 MDCAPMLSRRKRYHFEVVVRLHSLVAVPYVNAVTFAKLRLLDTRHTSQYSTRAEIRNHTVSWNTEHRFICKFRSNTGTNVLEPKFLKISIRMETKGGKSFYKVGFVIINLASFAAMGSATCRRRYILAGYDEKHKRQDNSLLLVSFSMRQLFGDTCFRIPPENLSNCL 168
BLAST of C2 NT-type domain-containing protein vs. TrEMBL
Match: A0A4E0RJJ3 (C2 NT-type domain-containing protein OS=Fasciola hepatica OX=6192 GN=D915_002417 PE=4 SV=1) HSP 1 Score: 201.83 bits (512), Expect = 2.985e-53 Identity = 88/168 (52.38%), Postives = 124/168 (73.81%), Query Frame = 2 Query: 116 MLCVP--TGKKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQD-KRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCV 610 M C P + +K Y FEV + L L ++P+VN + FAK+RLLD+R++ QYS+R I+NH V+WN+ H+F C+ +N TN+LEP +KIS+R E KGGKSF K+G+V++N+A FA +G CRRRYIL GY++ KRQDNS+L + F++ QLFGD CFR+P E+ S C+ Sbjct: 1 MDCAPMLSRRKRYHFEVVVRLHSLVAVPYVNAVTFAKLRLLDTRHTSQYSTRAEIRNHTVSWNTEHRFICKFRSNTGTNVLEPKFLKISIRMETKGGKSFYKVGFVIINLASFAAMGSATCRRRYILAGYDEKHKRQDNSLLLVSFSMRQLFGDTCFRIPPENLSNCL 168
BLAST of C2 NT-type domain-containing protein vs. TrEMBL
Match: A0A2H1CMN0 (C2 NT-type domain-containing protein OS=Fasciola hepatica OX=6192 GN=D915_03860 PE=4 SV=1) HSP 1 Score: 200.29 bits (508), Expect = 3.285e-53 Identity = 85/159 (53.46%), Postives = 120/159 (75.47%), Query Frame = 2 Query: 137 KKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQD-KRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCV 610 +K Y FEV + L L ++P+VN + FAK+RLLD+R++ QYS+R I+NH V+WN+ H+F C+ +N TN+LEP +KIS+R E KGGKSF K+G+V++N+A FA +G CRRRYIL GY++ KRQDNS+L + F++ QLFGD CFR+P E+ S C+ Sbjct: 5 RKRYHFEVVVRLHSLVAVPYVNAVTFAKLRLLDTRHTSQYSTRAEIRNHTVSWNTEHRFICKFRSNTGTNVLEPKFLKISIRMETKGGKSFYKVGFVIINLASFAAMGSATCRRRYILAGYDEKHKRQDNSLLLVSFSMRQLFGDTCFRIPPENLSNCL 163
BLAST of C2 NT-type domain-containing protein vs. TrEMBL
Match: A0A4S2MMB5 (C2 NT-type domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000229 PE=4 SV=1) HSP 1 Score: 197.978 bits (502), Expect = 3.381e-52 Identity = 91/168 (54.17%), Postives = 120/168 (71.43%), Query Frame = 2 Query: 116 MLCVPTG--KKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQ-DKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCV 610 M CVP +K YQFE + L L S+P+VN + FAK+RLL +RNS QYS R I+NH V+WN+ HKF C+ +NV+T +LEP+ +KIS+R E KGGKSF K+G+V V++ACF LG+ RRRYILEGYN+ KR DNS+L + F++ QL GD CFR P E+ C+ Sbjct: 1 MACVPIPGRRKQYQFEAIVKLHSLISVPYVNAVTFAKLRLLGTRNSSQYSPRVEIRNHTVSWNTEHKFLCKFRSNVETTVLEPNILKISIRMETKGGKSFYKVGFVSVDLACFTALGNVTSRRRYILEGYNERHKRLDNSLLLVSFSMRQLLGDTCFRPPPENLRNCL 168
BLAST of C2 NT-type domain-containing protein vs. Ensembl Cavefish
Match: fam102bb (family with sequence similarity 102 member B [Source:NCBI gene;Acc:103041129]) HSP 1 Score: 132.88 bits (333), Expect = 2.293e-34 Identity = 66/144 (45.83%), Postives = 99/144 (68.75%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 V L+ELSS+PFVNG+LF K+RLLD S++ SSRE ++ + V W F C++ A+ T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G T RR +LEGY+ ++ RQDNS+L++ + + GDPCF+ P Sbjct: 11 VDFQLDELSSVPFVNGVLFCKVRLLDGGFSEE-SSREMVQANCVHWRKKFSFPCKMSASAGTGVLDPCVCRVSVRKELKGGKTYAKLGFADLNLAEFAGSGSTT--RRCLLEGYDTKNTRQDNSILKVVISTQLMSGDPCFKTP 151
BLAST of C2 NT-type domain-containing protein vs. Ensembl Cavefish
Match: fam102aa (protein FAM102A-like [Source:NCBI gene;Acc:103038477]) HSP 1 Score: 133.265 bits (334), Expect = 3.373e-34 Identity = 64/140 (45.71%), Postives = 94/140 (67.14%), Query Frame = 2 Query: 170 LEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G T R +LEGYN ++ RQDNS+L++ + L DPCF+ P Sbjct: 18 LEELTAVPFVNGVLFCKIRLLDGGDFAASSSREEVRENSVRWRKRFSFVCKMSANPNTGVLDPCICRVSVRKELKGGKAYSKLGFADLNMAEFAGSGSTV--RCSLLEGYNTKNTRQDNSILKVTIEMTLLSADPCFKAP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Cavefish
Match: fam102bb (family with sequence similarity 102 member B [Source:NCBI gene;Acc:103041129]) HSP 1 Score: 133.265 bits (334), Expect = 3.642e-34 Identity = 66/144 (45.83%), Postives = 99/144 (68.75%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 V L+ELSS+PFVNG+LF K+RLLD S++ SSRE ++ + V W F C++ A+ T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G T RR +LEGY+ ++ RQDNS+L++ + + GDPCF+ P Sbjct: 11 VDFQLDELSSVPFVNGVLFCKVRLLDGGFSEE-SSREMVQANCVHWRKKFSFPCKMSASAGTGVLDPCVCRVSVRKELKGGKTYAKLGFADLNLAEFAGSGSTT--RRCLLEGYDTKNTRQDNSILKVVISTQLMSGDPCFKTP 151
BLAST of C2 NT-type domain-containing protein vs. Ensembl Cavefish
Match: fam102ab (family with sequence similarity 102 member A [Source:NCBI gene;Acc:103033975]) HSP 1 Score: 130.954 bits (328), Expect = 3.044e-33 Identity = 64/145 (44.14%), Postives = 97/145 (66.90%), Query Frame = 2 Query: 155 EVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 +V LEEL+++PF+NG+LF K+RLL+ + SSR+ ++ + V W F C++ AN T +L+P ++SVRKE+KGGK+F K+G+ +N+A FA G T R ILEGY+ ++ RQDNS+L++ + L GDPCF+ P Sbjct: 13 QVHFTLEELTAVPFINGMLFCKIRLLEGGDFAIASSRQEVQENCVRWRKKFSFVCKMSANPTTGVLDPCICRVSVRKELKGGKAFSKLGFADLNMAEFAGSGSTV--RCCILEGYDTKNTRQDNSILKVTIGMTLLSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Cavefish
Match: fam102bb (family with sequence similarity 102 member B [Source:NCBI gene;Acc:103041129]) HSP 1 Score: 118.627 bits (296), Expect = 3.927e-29 Identity = 60/129 (46.51%), Postives = 90/129 (69.77%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMH 541 V L+ELSS+PFVNG+LF K+RLLD S++ SSRE ++ + V W F C++ A+ T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G T RR +LEGY+ ++ RQDNS+L++ Sbjct: 11 VDFQLDELSSVPFVNGVLFCKVRLLDGGFSEE-SSREMVQANCVHWRKKFSFPCKMSASAGTGVLDPCVCRVSVRKELKGGKTYAKLGFADLNLAEFAGSGSTT--RRCLLEGYDTKNTRQDNSILKVQ 136
BLAST of C2 NT-type domain-containing protein vs. Ensembl Sea Lamprey
Match: fam102aa (family with sequence similarity 102 member Aa [Source:ZFIN;Acc:ZDB-GENE-081104-233]) HSP 1 Score: 139.428 bits (350), Expect = 4.083e-37 Identity = 66/151 (43.71%), Postives = 102/151 (67.55%), Query Frame = 2 Query: 137 KKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 KK Y+F+V L L+ELS +PF+N +LF K+RLLD N YSSRE ++ + V W +F C++ A+ + +L+ ++S+RKE+KGGK++ K+G+ +N+A FA G RR +LEGY+ ++ RQDNS+L++ + L GDPCF+ P Sbjct: 7 KKRYRFQVVLELDELSHIPFLNAVLFCKLRLLDGGNFTDYSSREEVRENCVRWKKKFEFVCKMTASPTSGVLDHCVCRVSIRKELKGGKAYSKLGFADLNMAEFA--GSRCTTRRCLLEGYDTKNARQDNSILKVIIGMTLLSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Medaka
Match: fam102ba (protein FAM102B [Source:NCBI gene;Acc:101166419]) HSP 1 Score: 143.28 bits (360), Expect = 7.085e-38 Identity = 71/151 (47.02%), Postives = 105/151 (69.54%), Query Frame = 2 Query: 137 KKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 KK ++F++ L+ELSS+PFVNG+LF K+RLLD +++ SSR+P+ + V W F C++ AN T +L+P ++SVRKE KGGK+F KMG+ +N++ FA G T RR +LEGY+ ++ RQDNS+L++ T + GDPCF+VP Sbjct: 8 KKRFKFKIDFDLDELSSVPFVNGVLFCKVRLLDGGFAEE-SSRQPVHANCVRWKKKFSFLCKISANSGTGVLDPCMCRVSVRKEKKGGKTFAKMGFADLNLSEFAGSGTTV--RRCLLEGYDTKNTRQDNSILKVVITTQLMSGDPCFKVP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Medaka
Match: fam102bb (family with sequence similarity 102 member B [Source:NCBI gene;Acc:101160726]) HSP 1 Score: 138.658 bits (348), Expect = 4.389e-36 Identity = 68/144 (47.22%), Postives = 100/144 (69.44%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 V L+ELSS+PFVNG+LF K+RLLD S++ SSREP++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ + GDPCF+ P Sbjct: 15 VDFELDELSSVPFVNGVLFCKVRLLDGGFSEE-SSREPVQANCVRWRKQFSFPCKMSANAGTGVLDPCVCRVSVRKELKGGKTYAKLGFADLNLAEFAGSGNTT--RRCLLEGYDTKNTRQDNSILKVIIGTQLMSGDPCFKTP 155
BLAST of C2 NT-type domain-containing protein vs. Ensembl Medaka
Match: fam102aa (family with sequence similarity 102 member A [Source:NCBI gene;Acc:101157302]) HSP 1 Score: 127.872 bits (320), Expect = 3.186e-32 Identity = 65/145 (44.83%), Postives = 98/145 (67.59%), Query Frame = 2 Query: 155 EVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 + L LEEL+++PFVNG+LF K+RLLD + SSRE ++ + V W F ++ AN T +L+PS ++SVRKE+KGGK+++K+G+ +N+A FA G T R +LEGY+ ++ RQDNS+L++ + L GDPCF+ P Sbjct: 13 QTQLTLEELTAVPFVNGVLFCKLRLLDG-DFVATSSREEVQENCVCWRKRFTFVSKMSANPHTGVLDPSVCRVSVRKELKGGKAYMKLGFTDLNMAEFAGSGSTI--RCCLLEGYDTKNTRQDNSILKVIIGMTLLSGDPCFKRP 154
BLAST of C2 NT-type domain-containing protein vs. Ensembl Medaka
Match: fam102bb (family with sequence similarity 102 member B [Source:NCBI gene;Acc:101160726]) HSP 1 Score: 125.176 bits (313), Expect = 1.969e-31 Identity = 63/132 (47.73%), Postives = 93/132 (70.45%), Query Frame = 2 Query: 158 VTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTV 550 V L+ELSS+PFVNG+LF K+RLLD S++ SSREP++ + V W F C++ AN T +L+P ++SVRKE+KGGK++ K+G+ +N+A FA G+T RR +LEGY+ ++ RQDNS+L++ V Sbjct: 11 VDFELDELSSVPFVNGVLFCKVRLLDGGFSEE-SSREPVQANCVRWRKQFSFPCKMSANAGTGVLDPCVCRVSVRKELKGGKTYAKLGFADLNLAEFAGSGNTT--RRCLLEGYDTKNTRQDNSILKVPGCV 139
BLAST of C2 NT-type domain-containing protein vs. Ensembl Medaka
Match: fam102ba (protein FAM102B [Source:NCBI gene;Acc:101166419]) HSP 1 Score: 121.709 bits (304), Expect = 4.022e-30 Identity = 64/151 (42.38%), Postives = 97/151 (64.24%), Query Frame = 2 Query: 137 KKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYN-QDKRQDNSMLQMHFTVCQLFGDPCFRVP 586 KK ++F++ L+ELSS+PFVNG+LF K+RLLD +++ SSR+P+ + V W F C++ AN T +L+P ++SVR KMG+ +N++ FA G T RR +LEGY+ ++ RQDNS+L++ T + GDPCF+VP Sbjct: 8 KKRFKFKIDFDLDELSSVPFVNGVLFCKVRLLDGGFAEE-SSRQPVHANCVRWKKKFSFLCKISANSGTGVLDPCMCRVSVR----------KMGFADLNLSEFAGSGTTV--RRCLLEGYDTKNTRQDNSILKVVITTQLMSGDPCFKVP 145
BLAST of C2 NT-type domain-containing protein vs. Planmine SMEST
Match: SMESG000015934.1 (SMESG000015934.1) HSP 1 Score: 739.569 bits (1908), Expect = 0.000e+0 Identity = 389/390 (99.74%), Postives = 389/390 (99.74%), Query Frame = 2 Query: 116 MLCVPTGKKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVPYEVFSQNKLLIVTPNSSLEGIDGLLDSEPIDSEGNVASFLLNLDQECGITKSGVKLQSKDAVTNIYNEISRQNLTRSQENSSPDYFKKVSNDHCWDVQLGEPLIATIPKFSKQTALTQNPGYSTCPHPMSHSKLSNVSTSQSSKFQPIQLDLDIKSESDHRKHRRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCTHSRSPQNWISTSLDRCEEQNMIPP 1285 MLCVPTGKKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVPYEVFSQNKLLIVTPNSSLEGIDGLLDSEPID EGNVASFLLNLDQECGITKSGVKLQSKDAVTNIYNEISRQNLTRSQENSSPDYFKKVSNDHCWDVQLGEPLIATIPKFSKQTALTQNPGYSTCPHPMSHSKLSNVSTSQSSKFQPIQLDLDIKSESDHRKHRRFGSSTQGSGSTAAKTTSSGYGSHSRHSSNESTSCTHSRSPQNWISTSLDRCEEQNMIPP Sbjct: 1 MLCVPTGKKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCVPYEVFSQNKLLIVTPNSSLEGIDGLLDSEPIDPEGNVASFLLNLDQECGITKSGVKLQSKDAVTNIYNEISRQNLTRSQENSSPDYFKKVSNDHCWDVQLGEPLIATIPKFSKQTALTQNPGYSTCPHPMSHSKLSNVSTSQSSKFQPIQLDLDIKSESDHRKHRRFGSSTQGSGSTAAKTTSSGYGSHSRHSSNESTSCTHSRSPQNWISTSLDRCEEQNMIPP 390
BLAST of C2 NT-type domain-containing protein vs. Planmine SMEST
Match: SMESG000020475.1 (SMESG000020475.1) HSP 1 Score: 165.622 bits (418), Expect = 9.504e-47 Identity = 75/157 (47.77%), Postives = 102/157 (64.97%), Query Frame = 2 Query: 140 KSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCV 610 K F +TL LEELSS+P VNGI FAK++ L+S YS + NH V W S H C+L +TN LE + +KI++++E GK+ G+V++NI+ FA+ G+ CRRRYIL N+ RQ NS+LQ+ +CQ FGDPCFRVP+ED S C+ Sbjct: 2 KKVHFNITLLLEELSSVPCVNGIFFAKIKFLESLKMTSYSPHTSVSNHKVQWKSNHAIMCKLAIEPETNTLESAFLKITIKQESTDGKTSTNYGFVIINISSFADKGNVECRRRYILASKNESIRQTNSLLQISLQMCQTFGDPCFRVPEEDFSSCI 158
BLAST of C2 NT-type domain-containing protein vs. Planmine SMEST
Match: SMESG000020475.1 (SMESG000020475.1) HSP 1 Score: 165.622 bits (418), Expect = 1.407e-46 Identity = 75/157 (47.77%), Postives = 102/157 (64.97%), Query Frame = 2 Query: 140 KSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSREPIKNHVVTWNSTHKFQCRLVANVQTNMLEPSEMKISVRKEIKGGKSFLKMGYVLVNIACFANLGDTACRRRYILEGYNQDKRQDNSMLQMHFTVCQLFGDPCFRVPDEDTSKCV 610 K F +TL LEELSS+P VNGI FAK++ L+S YS + NH V W S H C+L +TN LE + +KI++++E GK+ G+V++NI+ FA+ G+ CRRRYIL N+ RQ NS+LQ+ +CQ FGDPCFRVP+ED S C+ Sbjct: 17 KKVHFNITLLLEELSSVPCVNGIFFAKIKFLESLKMTSYSPHTSVSNHKVQWKSNHAIMCKLAIEPETNTLESAFLKITIKQESTDGKTSTNYGFVIINISSFADKGNVECRRRYILASKNESIRQTNSLLQISLQMCQTFGDPCFRVPEEDFSSCI 173 The following BLAST results are available for this feature:
BLAST of C2 NT-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 3
BLAST of C2 NT-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of C2 NT-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of C2 NT-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of C2 NT-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of C2 NT-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of C2 NT-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of C2 NT-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of C2 NT-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of C2 NT-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of C2 NT-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of C2 NT-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of C2 NT-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of C2 NT-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034396 ID=SMED30034396|Name=C2 NT-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1534bpback to top protein sequence of SMED30034396-orf-1 >SMED30034396-orf-1 ID=SMED30034396-orf-1|Name=SMED30034396-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=391bp MLCVPTGKKSYQFEVTLGLEELSSLPFVNGILFAKMRLLDSRNSKQYSSRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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