Protein YIPF3

Overview


Name	Protein YIPF3
Smed ID	SMED30034372
Length (bp)	1156

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein YIPF3 (SMED30034372) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein YIPF3 (SMED30034372) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein YIPF3 (SMED30034372) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein YIPF3 (SMED30034372) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034372

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
neoblast	SMED30034372	h1SMcG0015056	dd_Smed_v4_2055_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30034372	h1SMcG0015056	dd_Smed_v4_2055_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30034372	h1SMcG0015056	dd_Smed_v4_2055_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Protein YIPF3 vs. Ensembl Human
Match: YIPF3 (Yip1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:21023])

HSP 1 Score: 151.754 bits (382), Expect = 7.176e-42
Identity = 75/163 (46.01%), Postives = 113/163 (69.33%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            +  ELYGP+M+  TL+A+LL  MK++ T ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q+  ++GYGL GHCIV+ +   IH    H  FY+ W + GGL + R+V +  +RT G ++R++   T+  LHM FLLYLHFAYH +V  + + ++
Sbjct:  149 IAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHL---HALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLE 308

HSP 2 Score: 53.5286 bits (127), Expect = 2.820e-7
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V  RLL + IP+ +
Sbjct:   96 QMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKM 142

[Close]

BLAST of Protein YIPF3 vs. Ensembl Human
Match: YIPF3 (Yip1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:21023])

HSP 1 Score: 151.754 bits (382), Expect = 7.704e-42
Identity = 75/163 (46.01%), Postives = 113/163 (69.33%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            +  ELYGP+M+  TL+A+LL  MK++ T ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q+  ++GYGL GHCIV+ +   IH    H  FY+ W + GGL + R+V +  +RT G ++R++   T+  LHM FLLYLHFAYH +V  + + ++
Sbjct:  155 IAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHL---HALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLE 314

HSP 2 Score: 53.5286 bits (127), Expect = 2.953e-7
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V  RLL + IP+ +
Sbjct:  102 QMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKM 148

[Close]

BLAST of Protein YIPF3 vs. Ensembl Human
Match: YIPF3 (Yip1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:21023])

HSP 1 Score: 83.5741 bits (205), Expect = 1.015e-17
Identity = 54/151 (35.76%), Postives = 79/151 (52.32%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAY 994
            +  ELYGP+M+  TL+A+LL  MK++ T           I+T                         +Q+  ++GYGL GHCIV+ +   IH    H  FY+ W + GGL + R+V +  +RT G ++R++   T+  LHM FLLYLHFAY
Sbjct:  149 IAGELYGPLMLVFTLVAILLHGMKTSDT----------IIITM------------------------LQMLALLGYGLFGHCIVLFITYNIHL---HALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAY 262

HSP 2 Score: 53.5286 bits (127), Expect = 1.637e-7
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V  RLL + IP+ +
Sbjct:   96 QMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKM 142

[Close]

BLAST of Protein YIPF3 vs. Ensembl Human
Match: YIPF3 (Yip1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:21023])

HSP 1 Score: 67.0106 bits (162), Expect = 5.601e-13
Identity = 30/46 (65.22%), Postives = 39/46 (84.78%), Query Frame = 2

Query:  551 ELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIG 688
            ELYGP+M+  TL+A+LL  MK++ T ++EGTLMGTAI TCFGYW+G
Sbjct:   90 ELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLG 135

[Close]

BLAST of Protein YIPF3 vs. Ensembl Human
Match: YIPF3 (Yip1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:21023])

HSP 1 Score: 54.6842 bits (130), Expect = 7.756e-9
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V  RLL + IP+ +
Sbjct:   61 QMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKM 107

[Close]

BLAST of Protein YIPF3 vs. Ensembl Celegans
Match: Y53C12A.3 (pep chromosome:WBcel235:II:9704882:9706240:-1 gene:WBGene00013139.1 transcript:Y53C12A.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y53C12A.3)

HSP 1 Score: 107.071 bits (266), Expect = 1.813e-26
Identity = 56/173 (32.37%), Postives = 100/173 (57.80%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIKNM*IILHCFK 1060
            V  +LYGP M+ LT++ALLL+ MK++G  +Q GTLMGTA+ TCFG W+  S  +W+  ++   +   + I +  GY LT  C+V+LL SL H  + H+ F+V+        + R+  I   ++   + R++     +  H+  ++YLHF +H+++ E+   + +  + ++  K
Sbjct:   92 VSPDLYGPTMLVLTMVALLLYNMKTSGIVIQNGTLMGTAMFTCFGSWMLISGALWIACFLLAAEQPFLTILSSFGYSLTSQCLVLLLTSLFHSSHDHLFFFVLLASFCVPSALRMGLIVCNQSRLPANRLLLIGIAIAAHLLLIIYLHFGFHVVLEELDEMVGDAIVDVNAIK 264

HSP 2 Score: 47.7506 bits (112), Expect = 5.902e-6
Identity = 18/43 (41.86%), Postives = 28/43 (65.12%), Query Frame = 1

Query:  226 VWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIP 354
            +W  G ++ +  F+SY  +D  RPYF+V+P  V  RL+ +FIP
Sbjct:   42 MWEAGSKQVQDTFQSYGRIDLFRPYFDVDPAEVRTRLIRSFIP 84

[Close]

BLAST of Protein YIPF3 vs. Ensembl Zebrafish
Match: yipf3 (Yip1 domain family, member 3 [Source:NCBI gene;Acc:334511])

HSP 1 Score: 152.525 bits (384), Expect = 2.152e-42
Identity = 75/163 (46.01%), Postives = 115/163 (70.55%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            V  ELYGP+M+  TL+A+LL  MK++GT ++EGTLMGTAI T FGYW+G S+ ++ LAY+ N ++  +Q+ +++GYGL GHC+V+ +   +HF   H  FY++W + GGL + R+V +  +RT G + R+I   ++  LHM FLLYLHFAYH +V  + + ++
Sbjct:  147 VAGELYGPMMLVFTLVAILLHGMKTSGTVIREGTLMGTAIGTGFGYWLGVSSFIYFLAYLCNAQITMLQMLSLLGYGLFGHCVVLFITYNVHF---HSLFYLLWMVIGGLSTLRMVAVLISRTVGQTPRLILCGSLAALHMLFLLYLHFAYHKMVEGILDTLE 306

HSP 2 Score: 52.7582 bits (125), Expect = 3.204e-7
Identity = 23/47 (48.94%), Postives = 32/47 (68.09%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            +VW  GK +A   F  YA++D LRPYF+VEP  V +RL+ + IPV +
Sbjct:   94 EVWQAGKRQASKAFNLYANIDILRPYFDVEPIQVRNRLVESLIPVRM 140

[Close]

BLAST of Protein YIPF3 vs. Ensembl Mouse
Match: Yipf3 (Yip1 domain family, member 3 [Source:MGI Symbol;Acc:MGI:106280])

HSP 1 Score: 149.058 bits (375), Expect = 1.171e-42
Identity = 76/156 (48.72%), Postives = 109/156 (69.87%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVS 1009
            V  ELYGP+M+  TL+A+LL  MK++ T ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q+  ++GYGL GHCIV+ +   IH    H  FY+ W + GGL + R+V +  +RT G ++R++   T+  LHM FLLYLHFAYH +V 
Sbjct:   51 VAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHL---HALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVE 203

[Close]

BLAST of Protein YIPF3 vs. Ensembl Mouse
Match: Yipf3 (Yip1 domain family, member 3 [Source:MGI Symbol;Acc:MGI:106280])

HSP 1 Score: 151.754 bits (382), Expect = 4.148e-42
Identity = 76/163 (46.63%), Postives = 113/163 (69.33%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            V  ELYGP+M+  TL+A+LL  MK++ T ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q+  ++GYGL GHCIV+ +   IH    H  FY+ W + GGL + R+V +  +RT G ++R++   T+  LHM FLLYLHFAYH +V  + + ++
Sbjct:  146 VAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHL---HALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLE 305

HSP 2 Score: 53.5286 bits (127), Expect = 2.192e-7
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V  RLL + IP+ +
Sbjct:   93 QMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKM 139

[Close]

BLAST of Protein YIPF3 vs. Ensembl Mouse
Match: Yipf3 (Yip1 domain family, member 3 [Source:MGI Symbol;Acc:MGI:106280])

HSP 1 Score: 110.538 bits (275), Expect = 4.069e-28
Identity = 56/115 (48.70%), Postives = 81/115 (70.43%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARV 886
            V  ELYGP+M+  TL+A+LL  MK++ T ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q+  ++GYGL GHCIV+ +   IH    H  FY+ W + GGL + R+
Sbjct:   57 VAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHL---HALFYLFWLLVGGLSTLRM 168

HSP 2 Score: 52.7582 bits (125), Expect = 1.172e-7
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V  RLL + IP+ +
Sbjct:    4 QMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKM 50

[Close]

BLAST of Protein YIPF3 vs. UniProt/SwissProt
Match: sp|Q3B8G4|YIPF3_XENLA (Protein YIPF3 OS=Xenopus laevis OX=8355 GN=yipf3 PE=2 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 1.532e-45
Identity = 81/177 (45.76%), Postives = 120/177 (67.80%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIKNM*IILHCFKISAD 1072
            +  ELYGP+M+  T++A+LL  MKS+GT ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q  +++GYGL GHCIV+ +   IHF   H  FY+ W   GGL + R+V +  +RT GH++R+I   T+  LHM FLLYLHFAYH +V  + + +    + L   +++ D
Sbjct:  147 IAGELYGPLMLVFTMVAILLHGMKSSGTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQTLSLLGYGLFGHCIVLFITYNIHF---HSLFYIFWLCIGGLSTLRMVAVLLSRTVGHTQRLIVCGTMAALHMLFLLYLHFAYHKVVEGILDTLDGQNVPLPIQRVARD 320

HSP 2 Score: 56.6102 bits (135), Expect = 1.389e-7
Identity = 24/47 (51.06%), Postives = 32/47 (68.09%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V HRLL + IPV +
Sbjct:   94 EMWQAGKRQASKAFNLYANIDILRPYFDVEPIQVRHRLLESMIPVKM 140

[Close]

BLAST of Protein YIPF3 vs. UniProt/SwissProt
Match: sp|Q5F384|YIPF3_CHICK (Protein YIPF3 OS=Gallus gallus OX=9031 GN=YIPF3 PE=2 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 8.649e-45
Identity = 79/163 (48.47%), Postives = 116/163 (71.17%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            +  ELYGP+M+  TL+A+LL  MK++ T ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  VQ+ +++GYGL GHCI +L+   IHF   H  FY+ W + GGL + R+V +  +RT GH++R+I   T+  LHM FLLYLHFAYH +V  + + ++
Sbjct:  144 IAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMVQMLSLLGYGLFGHCITLLVTYNIHF---HSLFYIFWLVVGGLSTLRMVAVLVSRTVGHTQRLILCGTLAALHMLFLLYLHFAYHKVVEGILDTLE 303

HSP 2 Score: 51.6026 bits (122), Expect = 5.511e-6
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V  RLL + +PV +
Sbjct:   91 QMWQVGKRQASKAFSLYANIDILRPYFDVEPVQVRTRLLESMVPVKM 137

[Close]

BLAST of Protein YIPF3 vs. UniProt/SwissProt
Match: sp|Q803Z2|YIPF3_DANRE (Protein YIPF3 OS=Danio rerio OX=7955 GN=yipf3 PE=2 SV=1)

HSP 1 Score: 152.525 bits (384), Expect = 1.625e-41
Identity = 75/163 (46.01%), Postives = 115/163 (70.55%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            V  ELYGP+M+  TL+A+LL  MK++GT ++EGTLMGTAI T FGYW+G S+ ++ LAY+ N ++  +Q+ +++GYGL GHC+V+ +   +HF   H  FY++W + GGL + R+V +  +RT G + R+I   ++  LHM FLLYLHFAYH +V  + + ++
Sbjct:  147 VAGELYGPMMLVFTLVAILLHGMKTSGTVIREGTLMGTAIGTGFGYWLGVSSFIYFLAYLCNAQITMLQMLSLLGYGLFGHCVVLFITYNVHF---HSLFYLLWMVIGGLSTLRMVAVLISRTVGQTPRLILCGSLAALHMLFLLYLHFAYHKMVEGILDTLE 306

HSP 2 Score: 52.7582 bits (125), Expect = 2.419e-6
Identity = 23/47 (48.94%), Postives = 32/47 (68.09%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            +VW  GK +A   F  YA++D LRPYF+VEP  V +RL+ + IPV +
Sbjct:   94 EVWQAGKRQASKAFNLYANIDILRPYFDVEPIQVRNRLVESLIPVRM 140

[Close]

BLAST of Protein YIPF3 vs. UniProt/SwissProt
Match: sp|Q6TUD4|YIPF3_RAT (Protein YIPF3 OS=Rattus norvegicus OX=10116 GN=Yipf3 PE=2 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 2.235e-41
Identity = 76/163 (46.63%), Postives = 113/163 (69.33%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            V  ELYGP+M+  TL+A+LL  MK++ T ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q+  ++GYGL GHCIV+ +   IH    H  FY+ W + GGL + R+V +  +RT G ++R++   T+  LHM FLLYLHFAYH +V  + + ++
Sbjct:  146 VAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHL---HALFYLFWLLLGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLE 305

HSP 2 Score: 53.5286 bits (127), Expect = 1.390e-6
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V  RLL + IP+ +
Sbjct:   93 QMWQAGKRQASKAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKM 139

[Close]

BLAST of Protein YIPF3 vs. UniProt/SwissProt
Match: sp|Q3UDR8|YIPF3_MOUSE (Protein YIPF3 OS=Mus musculus OX=10090 GN=Yipf3 PE=1 SV=1)

HSP 1 Score: 151.754 bits (382), Expect = 2.902e-41
Identity = 76/163 (46.63%), Postives = 113/163 (69.33%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            V  ELYGP+M+  TL+A+LL  MK++ T ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q+  ++GYGL GHCIV+ +   IH    H  FY+ W + GGL + R+V +  +RT G ++R++   T+  LHM FLLYLHFAYH +V  + + ++
Sbjct:  146 VAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHL---HALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLE 305

HSP 2 Score: 53.5286 bits (127), Expect = 1.534e-6
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            ++W  GK +A   F  YA++D LRPYF+VEP  V  RLL + IP+ +
Sbjct:   93 QMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKM 139

[Close]

BLAST of Protein YIPF3 vs. TrEMBL
Match: A0A1I8J2E2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 197.208 bits (500), Expect = 2.856e-57
Identity = 87/162 (53.70%), Postives = 124/162 (76.54%), Query Frame = 2

Query:  548 SELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIKN 1033
            SELYGPVM C TL+A+LL+EMKS+  +VQEGTLMG+A++T FGYW+G SA++W++AYI N +++P+Q+ T++GY LT H  VVLL +  H   SH  FY++W + GGL + ++V+ F  RTPGH+ERI+    + +LHM FLLYLHFAYH IVS+++  ++ 
Sbjct:   59 SELYGPVMTCFTLVAVLLYEMKSSDHRVQEGTLMGSAMITVFGYWLGVSALVWLVAYICNAQVKPIQVATLIGYALTSHVAVVLLTTFFHSTQSHKLFYLLWAVLGGLTTLKLVSTFVVRTPGHTERIVLCALVAILHMLFLLYLHFAYHKIVSDLSEVLEQ 220

HSP 2 Score: 58.5362 bits (140), Expect = 5.743e-6
Identity = 25/49 (51.02%), Postives = 36/49 (73.47%), Query Frame = 1

Query:  226 VWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNVKDN 372
            VW EG ++A+T   SYA+VD LRPYF+V+P  V +RLL +F+P  V ++
Sbjct:    5 VWQEGTKKAKTAISSYANVDLLRPYFDVQPMEVANRLLFSFVPARVSND 53

[Close]

BLAST of Protein YIPF3 vs. TrEMBL
Match: A0A1I8FZK9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002953g4 PE=4 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 5.457e-57
Identity = 87/162 (53.70%), Postives = 124/162 (76.54%), Query Frame = 2

Query:  548 SELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIKN 1033
            SELYGPVM C TL+A+LL+EMKS+  +VQEGTLMG+A++T FGYW+G SA++W++AYI N +++P+Q+ T++GY LT H  VVLL +  H   SH  FY++W + GGL + ++V+ F  RTPGH+ERI+    + +LHM FLLYLHFAYH IVS+++  ++ 
Sbjct:  110 SELYGPVMTCFTLVAVLLYEMKSSDHRVQEGTLMGSAMITVFGYWLGVSALVWLVAYICNAQVKPIQVATLIGYALTSHVAVVLLTTFFHSTQSHKLFYLLWAVLGGLTTLKLVSTFVVRTPGHTERIVLCALVAILHMLFLLYLHFAYHKIVSDLSEVLEQ 271

HSP 2 Score: 58.5362 bits (140), Expect = 7.234e-6
Identity = 25/49 (51.02%), Postives = 36/49 (73.47%), Query Frame = 1

Query:  226 VWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNVKDN 372
            VW EG ++A+T   SYA+VD LRPYF+V+P  V +RLL +F+P  V ++
Sbjct:   56 VWQEGTKKAKTAISSYANVDLLRPYFDVQPMEVANRLLFSFVPARVSND 104

[Close]

BLAST of Protein YIPF3 vs. TrEMBL
Match: A0A0L8GH58 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22033504mg PE=4 SV=1)

HSP 1 Score: 188.734 bits (478), Expect = 1.949e-52
Identity = 84/160 (52.50%), Postives = 119/160 (74.38%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVAN 1021
            +P ELYGP M+  TLIALLLF+MKS+G +VQEGTLMGT+ L CF YW GAS+ +++L+Y+ N ++  +Q+ +++GYGL GHCIVV + ++ H  +SH+ FY++W + GGL +AR+  +  +RT GHS+RII    I +LH+ FLLYLHFAYH  V E + 
Sbjct:  123 IPRELYGPTMVIFTLIALLLFQMKSSGHQVQEGTLMGTSFLVCFSYWFGASSAIFLLSYLCNIQVTMIQVLSMLGYGLFGHCIVVFVSTVTHTSHSHILFYMLWALVGGLSTARMAFVILSRTSGHSQRIIVCSAIAILHLAFLLYLHFAYHQTVEEFSE 282

[Close]

BLAST of Protein YIPF3 vs. TrEMBL
Match: A0A2T7PKX1 (Protein YIPF OS=Pomacea canaliculata OX=400727 GN=C0Q70_05312 PE=3 SV=1)

HSP 1 Score: 178.718 bits (452), Expect = 3.839e-49
Identity = 81/164 (49.39%), Postives = 121/164 (73.78%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIKN 1033
            +P ELYGP M+ LT+IALLL++MKS   +V +GTLMG+A+  CF YW GAS ++WVL+Y+ + K+  +Q+ +++GYG+ GHCIV+ LG+LIH  + H  FY++W I GGL + R+ TI  +RT   ++R++    + +LHM FLLYLHFAYH IV E+++A ++
Sbjct:  137 IPRELYGPTMVVLTMIALLLYQMKSAEHRVTDGTLMGSALGVCFAYWFGASCLVWVLSYVFSVKIVLIQVMSMVGYGMFGHCIVLFLGTLIHTSHDHAFFYLLWVIFGGLATLRMATILISRTKSKTDRLVVIGCLSLLHMMFLLYLHFAYHKIVEELSDAFQD 300

[Close]

BLAST of Protein YIPF3 vs. TrEMBL
Match: R7UF99 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_173547 PE=4 SV=1)

HSP 1 Score: 176.022 bits (445), Expect = 6.600e-49
Identity = 85/156 (54.49%), Postives = 117/156 (75.00%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVS 1009
            VP ELYGP M+  TLIALLLF+MK++G  VQEGTLMGTA   CFGYW G ++IMWVLAY+ NT++  +Q+ +++GYGL  HCIV+ LG++ H  +SH  FY+IW + GGL + ++V++  +RT G ++R+I   T+  +H+ FLLYLHFAYH IV 
Sbjct:  108 VPRELYGPTMVVFTLIALLLFQMKTSGHVVQEGTLMGTAFGICFGYWFGIASIMWVLAYVCNTRISMMQLLSLLGYGLFSHCIVLFLGTVWH-SSSHASFYMIWAVFGGLSTVKMVSVLTSRTIGRTQRLIVCGTLAFIHLVFLLYLHFAYHRIVE 262

[Close]

BLAST of Protein YIPF3 vs. Ensembl Cavefish
Match: yipf3 (Yip1 domain family member 3 [Source:NCBI gene;Acc:103024528])

HSP 1 Score: 160.229 bits (404), Expect = 1.824e-45
Identity = 78/163 (47.85%), Postives = 117/163 (71.78%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            V  ELYGP+M+  TL+A+LL  MK++GT ++EGTLMGTAI TCFGYW+G+S+ ++ LAY+ N ++  +Q+ +++GYGL GHC+V+ +   +HF   H  FY++W + GGL + R+V +  +RT G + R+I   T+  LHM FLLYLHFAYH IV  + + ++
Sbjct:  148 VAGELYGPMMLVFTLVAILLHGMKTSGTVIREGTLMGTAIGTCFGYWLGSSSFIYFLAYLCNAQITMLQMLSLLGYGLFGHCVVLFITYNVHF---HSLFYILWLVIGGLSTLRMVAVLISRTVGQTPRLIMCGTLAALHMLFLLYLHFAYHKIVEGILDTLE 307

HSP 2 Score: 51.9878 bits (123), Expect = 4.799e-7
Identity = 22/47 (46.81%), Postives = 32/47 (68.09%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            +VW  GK +A   F  YA++D LRPYF+VEP  V +RL+ + IP+ +
Sbjct:   95 EVWQAGKRQASKAFNLYANIDILRPYFDVEPIQVRNRLIESMIPLKM 141

[Close]

BLAST of Protein YIPF3 vs. Ensembl Sea Lamprey
Match: yipf3 (Yip1 domain family, member 3 [Source:NCBI gene;Acc:334511])

HSP 1 Score: 149.443 bits (376), Expect = 6.457e-43
Identity = 74/163 (45.40%), Postives = 114/163 (69.94%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            +  ELYGP+M+  T++A+LL  MK++ T ++EGTLMGTAI TCFGYW G S++++ +AY+ N ++  VQ+ +++GYGL G CIV+ +   +H    H  FY++W I GGL + R+V +  +RT GH++R++   T+  LHM FLLYLHFAYH I+  + ++  
Sbjct:   75 IAGELYGPLMLVFTMVAILLQGMKTSDTIIREGTLMGTAIGTCFGYWGGVSSLLYFMAYVCNAQITMVQLLSLLGYGLFGPCIVLFVTYNVHL---HSLFYLLWIIIGGLSTLRLVCVLVSRTVGHTQRLVLGGTVAALHMLFLLYLHFAYHRILEGLIDSFD 234

HSP 2 Score: 55.4546 bits (132), Expect = 4.561e-9
Identity = 23/47 (48.94%), Postives = 33/47 (70.21%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            +VW  GK++A   F  YA++D LRPYF+VEP  V +RLL + +PV +
Sbjct:   22 QVWRAGKQQATKAFTLYANIDILRPYFDVEPMQVRNRLLESLVPVRI 68

[Close]

BLAST of Protein YIPF3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002141.1 (pep scaffold:Pmarinus_7.0:GL481214:25234:28144:-1 gene:ENSPMAG00000001943.1 transcript:ENSPMAT00000002141.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 120.553 bits (301), Expect = 3.739e-33
Identity = 56/133 (42.11%), Postives = 89/133 (66.92%), Query Frame = 2

Query:  632 QEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            +EGTLMGTA+ TC GYW+GAS ++++LAY+  T++   Q   ++GY L GHC+V+L+   +H    H  F+ +W + GGL + R+V +  +R PG+ +R++   T+  LHM  LLYLHF YH +V E+  +++
Sbjct:    1 REGTLMGTALATCLGYWLGASGLLYLLAYVTGTRISMSQTLALIGYSLFGHCVVLLVTYNVHV---HALFFSLWVVVGGLSALRMVMVLASRAPGYRQRMVLCGTLASLHMLSLLYLHFTYHRVVEELMESLE 130

[Close]

BLAST of Protein YIPF3 vs. Ensembl Nematostella
Match: EDO47784 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL27])

HSP 1 Score: 106.301 bits (264), Expect = 2.471e-27
Identity = 56/115 (48.70%), Postives = 79/115 (68.70%), Query Frame = 2

Query:  551 ELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTI 895
            ELYGP+M+  TLIA+LLF MK++G  VQEGTLMGTA   CFGYW+G SA  + +AY  NT L  +QI ++ GY + G  +V L  + + + +SH  FY++W I GGL + ++V +
Sbjct:   58 ELYGPMMLVFTLIAVLLFGMKTSGHTVQEGTLMGTAFGLCFGYWLGGSAFCYCVAYFCNTHLTFLQICSLTGYAMFGQ-VVCLFFTTVGYHHSHSFFYMLWLIFGGLSALKLVRV 171

HSP 2 Score: 50.447 bits (119), Expect = 1.788e-7
Identity = 22/44 (50.00%), Postives = 29/44 (65.91%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIP 354
            +VW  GK+ A+  F  YA++D LRPYF+VEP  V  RL  + IP
Sbjct:    1 QVWQAGKQSAKRAFDLYANIDILRPYFDVEPTEVRSRLFHSLIP 44

[Close]

BLAST of Protein YIPF3 vs. Ensembl Medaka
Match: yipf3 (Yip1 domain family member 3 [Source:NCBI gene;Acc:101174527])

HSP 1 Score: 149.058 bits (375), Expect = 1.538e-42
Identity = 73/163 (44.79%), Postives = 118/163 (72.39%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            +  ELYGP+M+  TL+A+LL  MK++GT ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q+ +++GYGL G C+V+L+   +HF   HV FY++W + GGL + R+V +  +RT G + R++   ++ +LHM FL YLHF+YH I+  + ++++
Sbjct:   29 IAGELYGPLMLVFTLVAILLHGMKTSGTVIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLVNAQVTMLQMLSLLGYGLFGPCVVLLVTYNVHF---HVLFYLLWLLIGGLSTLRMVAVLLSRTVGRTPRLLLCGSLALLHMSFLFYLHFSYHRILEGLLDSLE 188

[Close]

BLAST of Protein YIPF3 vs. Ensembl Medaka
Match: yipf3 (Yip1 domain family member 3 [Source:NCBI gene;Acc:101174527])

HSP 1 Score: 149.058 bits (375), Expect = 2.665e-41
Identity = 73/163 (44.79%), Postives = 118/163 (72.39%), Query Frame = 2

Query:  542 VPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIK 1030
            +  ELYGP+M+  TL+A+LL  MK++GT ++EGTLMGTAI TCFGYW+G S+ ++ LAY+ N ++  +Q+ +++GYGL G C+V+L+   +HF   HV FY++W + GGL + R+V +  +RT G + R++   ++ +LHM FL YLHF+YH I+  + ++++
Sbjct:  144 IAGELYGPLMLVFTLVAILLHGMKTSGTVIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLVNAQVTMLQMLSLLGYGLFGPCVVLLVTYNVHF---HVLFYLLWLLIGGLSTLRMVAVLLSRTVGRTPRLLLCGSLALLHMSFLFYLHFSYHRILEGLLDSLE 303

HSP 2 Score: 50.8322 bits (120), Expect = 9.849e-7
Identity = 21/47 (44.68%), Postives = 29/47 (61.70%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNV 363
            +VW  GK +A   F  Y ++D LRPYF+VEP  V  RLL +  P+ +
Sbjct:   91 EVWQAGKRQASKAFSLYGNIDILRPYFDVEPAQVRSRLLESMFPIRM 137

[Close]

BLAST of Protein YIPF3 vs. Planmine SMEST
Match: SMESG000011552.1 (SMESG000011552.1)

HSP 1 Score: 343.199 bits (879), Expect = 7.582e-118
Identity = 167/167 (100.00%), Postives = 167/167 (100.00%), Query Frame = 2

Query:  536 CPVPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIKNM 1036
            CPVPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIKNM
Sbjct:   98 CPVPSELYGPVMICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAYIGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGGLCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVANAIKNM 264

HSP 2 Score: 107.842 bits (268), Expect = 1.179e-41
Identity = 50/52 (96.15%), Postives = 50/52 (96.15%), Query Frame = 1

Query:  223 KVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNVKDNDV 378
             VWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNVKDND 
Sbjct:   47 SVWAEGKERAETVFKSYASVDYLRPYFNVEPKVVLHRLLSAFIPVNVKDNDC 98

HSP 3 Score: 81.6481 bits (200), Expect = 1.179e-41
Identity = 40/40 (100.00%), Postives = 40/40 (100.00%), Query Frame = 2

Query:   65 RPAVIDMTDMTDNSIDTEKSDNSNKGSASNILFSKLTSSV 184
            RPAVIDMTDMTDNSIDTEKSDNSNKGSASNILFSKLTSSV
Sbjct:    9 RPAVIDMTDMTDNSIDTEKSDNSNKGSASNILFSKLTSSV 48

The following BLAST results are available for this feature:

BLAST of Protein YIPF3 vs. Ensembl Human
BLAST of Protein YIPF3 vs. Ensembl Celegans
BLAST of Protein YIPF3 vs. Ensembl Fly
BLAST of Protein YIPF3 vs. Ensembl Zebrafish
BLAST of Protein YIPF3 vs. Ensembl Xenopus
BLAST of Protein YIPF3 vs. Ensembl Mouse
BLAST of Protein YIPF3 vs. UniProt/SwissProt
BLAST of Protein YIPF3 vs. TrEMBL
BLAST of Protein YIPF3 vs. Ensembl Cavefish
BLAST of Protein YIPF3 vs. Ensembl Sea Lamprey
BLAST of Protein YIPF3 vs. Ensembl Yeast
BLAST of Protein YIPF3 vs. Ensembl Nematostella
BLAST of Protein YIPF3 vs. Ensembl Medaka
BLAST of Protein YIPF3 vs. Planmine SMEST

BLAST of Protein YIPF3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
YIPF3	7.176e-42	46.01	Yip1 domain family member 3 [Source:HGNC Symbol;Ac...	[more]
YIPF3	7.704e-42	46.01	Yip1 domain family member 3 [Source:HGNC Symbol;Ac...	[more]
YIPF3	1.015e-17	35.76	Yip1 domain family member 3 [Source:HGNC Symbol;Ac...	[more]
YIPF3	5.601e-13	65.22	Yip1 domain family member 3 [Source:HGNC Symbol;Ac...	[more]
YIPF3	7.756e-9	46.81	Yip1 domain family member 3 [Source:HGNC Symbol;Ac...	[more]

BLAST of Protein YIPF3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Y53C12A.3	1.813e-26	32.37	pep chromosome:WBcel235:II:9704882:9706240:-1 gene...	[more]

BLAST of Protein YIPF3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein YIPF3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
yipf3	2.152e-42	46.01	Yip1 domain family, member 3 [Source:NCBI gene;Acc...	[more]

BLAST of Protein YIPF3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein YIPF3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Yipf3	1.171e-42	48.72	Yip1 domain family, member 3 [Source:MGI Symbol;Ac...	[more]
Yipf3	4.148e-42	46.63	Yip1 domain family, member 3 [Source:MGI Symbol;Ac...	[more]
Yipf3	4.069e-28	48.70	Yip1 domain family, member 3 [Source:MGI Symbol;Ac...	[more]

BLAST of Protein YIPF3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q3B8G4\|YIPF3_XENLA	1.532e-45	45.76	Protein YIPF3 OS=Xenopus laevis OX=8355 GN=yipf3 P...	[more]
sp\|Q5F384\|YIPF3_CHICK	8.649e-45	48.47	Protein YIPF3 OS=Gallus gallus OX=9031 GN=YIPF3 PE...	[more]
sp\|Q803Z2\|YIPF3_DANRE	1.625e-41	46.01	Protein YIPF3 OS=Danio rerio OX=7955 GN=yipf3 PE=2...	[more]
sp\|Q6TUD4\|YIPF3_RAT	2.235e-41	46.63	Protein YIPF3 OS=Rattus norvegicus OX=10116 GN=Yip...	[more]
sp\|Q3UDR8\|YIPF3_MOUSE	2.902e-41	46.63	Protein YIPF3 OS=Mus musculus OX=10090 GN=Yipf3 PE...	[more]

BLAST of Protein YIPF3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8J2E2	2.856e-57	53.70	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8FZK9	5.457e-57	53.70	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A0L8GH58	1.949e-52	52.50	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]
A0A2T7PKX1	3.839e-49	49.39	Protein YIPF OS=Pomacea canaliculata OX=400727 GN=...	[more]
R7UF99	6.600e-49	54.49	Uncharacterized protein OS=Capitella teleta OX=283...	[more]

BLAST of Protein YIPF3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
yipf3	1.824e-45	47.85	Yip1 domain family member 3 [Source:NCBI gene;Acc:...	[more]

BLAST of Protein YIPF3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
yipf3	6.457e-43	45.40	Yip1 domain family, member 3 [Source:NCBI gene;Acc...	[more]
ENSPMAT00000002141.1	3.739e-33	42.11	pep scaffold:Pmarinus_7.0:GL481214:25234:28144:-1 ...	[more]

BLAST of Protein YIPF3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein YIPF3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO47784	2.471e-27	48.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein YIPF3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
yipf3	1.538e-42	44.79	Yip1 domain family member 3 [Source:NCBI gene;Acc:...	[more]
yipf3	2.665e-41	44.79	Yip1 domain family member 3 [Source:NCBI gene;Acc:...	[more]

BLAST of Protein YIPF3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000011552.1	7.582e-118	100.00	SMESG000011552.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034372 ID=SMED30034372|Name=Protein YIPF3|organism=Schmidtea mediterranea sexual|type=transcript|length=1156bp
TGAAGATAATGTAAGTAATATAGCGAGAAACTATGACAATGAGTCCAATA
CTTATACATTTCAGAGACCAGCCGTCATTGATATGACTGATATGACGGAT
AATTCGATAGATACAGAAAAATCAGATAATAGTAACAAAGGGTCAGCTTC
AAACATCCTTTTTTCTAAATTGACATCATCAGTTGTTAAATAATTTTTTA
TTTGTTTTGTTAATCACCCTTTAAGGTATGGGCTGAAGGAAAAGAACGAG
CAGAAACGGTTTTTAAATCATATGCCAGTGTTGATTATTTAAGACCTTAT
TTTAATGTTGAACCTAAGGTAGTATTGCATCGATTGCTATCAGCTTTTAT
CCCAGTTAATGTCAAAGATAATGATGTAAAATTTATTTTTATTAATCCTA
AGGAAAATATTCAGCATCATTTACTAAAGGGAAATTTCAATTATAACGTA
AATCAATAAATAATTCCCATTTATTGTCACTGGTGCTATATATTTTCTTT
AAAGTCAGGCAAATCTAATTATCGGTATTGAATAGTGTCCAGTGCCATCT
GAATTGTACGGCCCGGTTATGATTTGCTTAACACTAATTGCCCTACTTCT
TTTTGAAATGAAGTCAACCGGAACGAAAGTGCAAGAAGGAACTCTGATGG
GCACTGCAATATTAACATGCTTTGGTTATTGGATCGGAGCAAGTGCTATC
ATGTGGGTTCTGGCCTACATAGGAAATACCAAATTGCGACCGGTTCAAAT
CAACACTGTCATGGGCTATGGATTAACGGGTCACTGTATTGTTGTCTTAT
TGGGAAGTCTTATTCATTTCGGCAACAGCCACGTTCCGTTCTATGTGATA
TGGGGAATTTGTGGAGGATTATGCTCAGCTAGAGTTGTCACTATTTTCTG
GGCCAGAACGCCGGGCCATTCAGAGAGAATAATTTCCGCTGTTACTATTG
TCGTATTGCACATGGGGTTCTTGCTATATCTTCATTTTGCTTATCACTTG
ATCGTCTCAGAAGTTGCCAATGCAATTAAGAATATGTAAATCATTTTGCA
TTGTTTCAAAATTTCTGCTGATTGCATTGAGGTTAGATATACTTTCTAAT
TTTGTGAGTTCCTATTGGCTCTACTATCACTACTATTATTTTATTGAATA
AATGGA

protein sequence of SMED30034372-orf-1

>SMED30034372-orf-1 ID=SMED30034372-orf-1|Name=SMED30034372-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=157bp
MICLTLIALLLFEMKSTGTKVQEGTLMGTAILTCFGYWIGASAIMWVLAY
IGNTKLRPVQINTVMGYGLTGHCIVVLLGSLIHFGNSHVPFYVIWGICGG
LCSARVVTIFWARTPGHSERIISAVTIVVLHMGFLLYLHFAYHLIVSEVA
NAIKNM*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis

Vocabulary: **INTERPRO**
Term	Definition
IPR026637	YIPF3

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PANTHER	PTHR15627	NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1	coord: 1..151
None	No IPR available	SIGNALP_EUK	SignalP-TM	SignalP-TM	coord: 1..18 score: 0.787
None	No IPR available	TMHMM	TMhelix		coord: 89..111
None	No IPR available	TMHMM	TMhelix		coord: 63..85
None	No IPR available	TMHMM	TMhelix		coord: 124..146
None	No IPR available	TMHMM	TMhelix		coord: 28..50
IPR026637	YIP1 family member 3	PANTHER	PTHR15627:SF14	PROTEIN YIPF3	coord: 1..151

Main menu

Protein YIPF3

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

blazegraph-runner