Cytidine deaminase

Overview
NameCytidine deaminase
Smed IDSMED30034331
Length (bp)589
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cytidine deaminase (SMED30034331) t-SNE clustered cells

Violin plots show distribution of expression levels for Cytidine deaminase (SMED30034331) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cytidine deaminase (SMED30034331) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cytidine deaminase (SMED30034331) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30034331

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pigment cellSMED30034331h1SMcG0009949 SmedASXL_008500SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30034331h1SMcG0009949 Contig46685uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30034331h1SMcG0009949 Contig46685newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30034331h1SMcG0009949 dd_Smed_v4_3308_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30034331h1SMcG0009949 dd_Smed_v4_3308_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30034331h1SMcG0009949 dd_Smed_v4_3308_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30034331h1SMcG0009949 dd_Smed_v4_3308_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cytidine deaminase vs. Ensembl Human
Match: CDA (cytidine deaminase [Source:HGNC Symbol;Acc:HGNC:1712])

HSP 1 Score: 116.316 bits (290), Expect = 7.777e-33
Identity = 58/138 (42.03%), Postives = 85/138 (61.59%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTE-KFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFD-EDFKEDK 494
            + PE + +++  + ++K +AYCPYS F VGA++L   G+I+ GCNIEN  YP G+CAE TA  KAVS+    F A+ +A+D +  FI PCG CRQ + EF T N  +            T++ELLP +F  ED ++ +
Sbjct:   10 LKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGT-NWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ 146
[Close]
BLAST of Cytidine deaminase vs. Ensembl Celegans
Match: cdd-2 (Cytidine deaminase [Source:UniProtKB/TrEMBL;Acc:Q20628])

HSP 1 Score: 100.908 bits (250), Expect = 4.705e-27
Identity = 53/133 (39.85%), Postives = 76/133 (57.14%), Query Frame = 3 
Query:  108 EMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDED----FKEDK 494
            E++ +A  +   A+CPYSKF VGA++L  +G+I  GCN+EN SY   +CAE +A   AVS    KF A+ V  +  +   PCG CRQFL EF    + ++     NK    +   LLPFAF  +    F+++K
Sbjct:   14 ELVHLARAAMKRAHCPYSKFPVGAALLTESGEIVQGCNVENASYGGTICAERSAIVSAVSQGYTKFRAIAVVTELSEPASPCGLCRQFLVEFGDYKV-VVGTASNNKILITSTRALLPFAFTPESLDTFEQEK 145
[Close]
BLAST of Cytidine deaminase vs. Ensembl Celegans
Match: cdd-1 (Cytidine deaminase [Source:UniProtKB/TrEMBL;Acc:Q22922])

HSP 1 Score: 82.4185 bits (202), Expect = 5.320e-20
Identity = 50/136 (36.76%), Postives = 74/136 (54.41%), Query Frame = 3 
Query:   96 EILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDEDFKEDK*KQ 503
            E   +++  A  +   AYC YS FKVGA+++  +G+I  G N EN SY   +CAE +A   A++    KF  +VVA + E    PCG CRQ L EF    + I+  + +++    T  ELLP+AF     +D  K+
Sbjct:   10 EFEQQLVDKAIGAMENAYCKYSNFKVGAALVCDDGEIIIGANHENASYGATICAERSAIVTALTKGHRKFKYIVVATELEAPCSPCGVCRQVLIEFGDYKV-ILGSSTSDQIIETTTYELLPYAFTPKSLDDHEKE 144
[Close]
BLAST of Cytidine deaminase vs. Ensembl Fly
Match: CG8360 (gene:FBgn0032001 transcript:FBtr0332414)

HSP 1 Score: 103.605 bits (257), Expect = 4.394e-28
Identity = 60/138 (43.48%), Postives = 84/138 (60.87%), Query Frame = 3 
Query:   72 KLFLIMNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIA-VVVANDTEKFIRPCGQCRQFLSEF-STKNMQIISLNKTN---KSDTKTIEELLPFAF 470
            + F  ++P I  E+I  A +++  AYCPYS F VGA++   +G IYSGCNIEN +Y   +CAE TAA KA+S+    F+A  VVA     F  PCG CRQFLSEF + K++ + +   TN   +    ++ +LLP  F
Sbjct:   16 REFQSLDPSI-QEIILAATEARKQAYCPYSNFAVGAALRTSDGTIYSGCNIENGAYATCICAERTAAVKAISEGKRDFVACAVVAQQDNGFTTPCGVCRQFLSEFVNGKDIPLYAAKPTNLPLRVLCTSVLQLLPNGF 152
[Close]
BLAST of Cytidine deaminase vs. Ensembl Fly
Match: CG8360 (gene:FBgn0032001 transcript:FBtr0089935)

HSP 1 Score: 103.605 bits (257), Expect = 4.394e-28
Identity = 60/138 (43.48%), Postives = 84/138 (60.87%), Query Frame = 3 
Query:   72 KLFLIMNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIA-VVVANDTEKFIRPCGQCRQFLSEF-STKNMQIISLNKTN---KSDTKTIEELLPFAF 470
            + F  ++P I  E+I  A +++  AYCPYS F VGA++   +G IYSGCNIEN +Y   +CAE TAA KA+S+    F+A  VVA     F  PCG CRQFLSEF + K++ + +   TN   +    ++ +LLP  F
Sbjct:   16 REFQSLDPSI-QEIILAATEARKQAYCPYSNFAVGAALRTSDGTIYSGCNIENGAYATCICAERTAAVKAISEGKRDFVACAVVAQQDNGFTTPCGVCRQFLSEFVNGKDIPLYAAKPTNLPLRVLCTSVLQLLPNGF 152
[Close]
BLAST of Cytidine deaminase vs. Ensembl Fly
Match: CG8353 (gene:FBgn0032002 transcript:FBtr0332415)

HSP 1 Score: 94.7449 bits (234), Expect = 2.085e-24
Identity = 47/108 (43.52%), Postives = 71/108 (65.74%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILG-VNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIA-VVVANDTEKFIRPCGQCRQFLSEFSTKNMQI 404
            ++P +  E++  A + +  AY PYS FKVGA+    V+GKI++GCN+EN ++  G CAE TA +KAVS+   +F+A  V+A +   F  PCG CRQF+ EF+  ++ I
Sbjct:   23 LDPSV-QELLTAAFQVRQRAYVPYSGFKVGAAFRAKVDGKIFTGCNVENAAFTPGSCAERTAIAKAVSEGATEFLAGAVLAYEPNVFTTPCGVCRQFIREFANADIPI 129
[Close]
BLAST of Cytidine deaminase vs. Ensembl Fly
Match: CG8353 (gene:FBgn0032002 transcript:FBtr0079593)

HSP 1 Score: 94.7449 bits (234), Expect = 2.085e-24
Identity = 47/108 (43.52%), Postives = 71/108 (65.74%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILG-VNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIA-VVVANDTEKFIRPCGQCRQFLSEFSTKNMQI 404
            ++P +  E++  A + +  AY PYS FKVGA+    V+GKI++GCN+EN ++  G CAE TA +KAVS+   +F+A  V+A +   F  PCG CRQF+ EF+  ++ I
Sbjct:   23 LDPSV-QELLTAAFQVRQRAYVPYSGFKVGAAFRAKVDGKIFTGCNVENAAFTPGSCAERTAIAKAVSEGATEFLAGAVLAYEPNVFTTPCGVCRQFIREFANADIPI 129
[Close]
BLAST of Cytidine deaminase vs. Ensembl Fly
Match: CG8349 (gene:FBgn0032003 transcript:FBtr0079594)

HSP 1 Score: 87.0409 bits (214), Expect = 9.588e-21
Identity = 45/101 (44.55%), Postives = 63/101 (62.38%), Query Frame = 3 
Query:  105 NEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIA-VVVANDTEKFIRPCGQCRQFLSEFSTKNMQI 404
             E+++ A  ++  AY PYSKFKVGA+     G+IY+GCNIEN ++  G CAE  A +K +S+   K+ A  VVA   + F  PCG CRQF+ EF   ++ I
Sbjct:  124 RELLEAALSARRCAYAPYSKFKVGAAFRAKCGRIYAGCNIENVAFTPGNCAERCALAKGISEGEKKYTAGAVVAYHPDGFTTPCGVCRQFILEFIQNDIPI 224
[Close]
BLAST of Cytidine deaminase vs. Ensembl Zebrafish
Match: cdaa (cytidine deaminase a [Source:ZFIN;Acc:ZDB-GENE-170609-2])

HSP 1 Score: 120.939 bits (302), Expect = 5.659e-35
Identity = 60/132 (45.45%), Postives = 91/132 (68.94%), Query Frame = 3 
Query:   90 NPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTE-KFIRPCGQCRQFLSEFSTKNMQIISLNKTNKS-DTKTIEELLPFAFDED 479
            NP++L   ++ + +++  AYCPYS+F+VGA++L  +G +++GCN+EN  Y  G+CAE TA SKAVS+    F A+ +A+D E +FI PCG CRQF+ EF ++    + L+KT+ S    T+EELLP +F  D
Sbjct:    5 NPQVL---VQRSQEARKLAYCPYSRFRVGAAVLTSDGTVFTGCNVENACYTAGLCAERTAISKAVSEGHTTFKAIAIASDLEDRFISPCGACRQFMREFGSQ--WDVYLSKTDGSFKQMTVEELLPCSFGPD 131
[Close]
BLAST of Cytidine deaminase vs. Ensembl Zebrafish
Match: cdab (cytidine deaminase b [Source:ZFIN;Acc:ZDB-GENE-040426-1911])

HSP 1 Score: 113.62 bits (283), Expect = 9.674e-32
Identity = 61/134 (45.52%), Postives = 90/134 (67.16%), Query Frame = 3 
Query:  102 LNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDT-EKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTK-TIEELLPFAFD-EDFKEDK 494
            + E+ + + ++K  AYCPYSKF+VGA++L  +G +++GCN+EN  +  G+CAE  A SKAVS+    F A+ +A+D  E FI PCG CRQF+ EF + N ++  L+K + S  + T+EELLP +F  ED K  K
Sbjct:   21 IKELTRKSQEAKKFAYCPYSKFRVGAALLTHDGTVFTGCNVENACFNLGICAERVAISKAVSEGYRDFKAIAIASDMCENFISPCGGCRQFMREFGS-NWEVY-LSKPDGSYVEMTVEELLPASFGPEDLKMKK 152
[Close]
BLAST of Cytidine deaminase vs. Ensembl Zebrafish
Match: zgc:103586 (zgc:103586 [Source:ZFIN;Acc:ZDB-GENE-041114-88])

HSP 1 Score: 102.449 bits (254), Expect = 1.082e-27
Identity = 55/123 (44.72%), Postives = 75/123 (60.98%), Query Frame = 3 
Query:  108 EMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDT-EKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKT-IEELLPFAF 470
            E++    +++  AYCPYS F VGA+IL   G I +GCN+EN SY   VCAE TA  +AV++   +F A+ V  D  + F+ PCG CRQ L EF T+    + L K + S  KT + +LLP AF
Sbjct:    5 ELVAKCLQAREMAYCPYSGFPVGAAILTTGGAIVTGCNVENASYGLTVCAERTAIQRAVAEGYRRFTAIAVTCDIKDSFVGPCGACRQVLMEFGTE--WDVYLTKPDGSYRKTSLRDLLPLAF 125
[Close]
BLAST of Cytidine deaminase vs. Ensembl Zebrafish
Match: zgc:103586 (zgc:103586 [Source:ZFIN;Acc:ZDB-GENE-041114-88])

HSP 1 Score: 102.449 bits (254), Expect = 1.082e-27
Identity = 55/123 (44.72%), Postives = 75/123 (60.98%), Query Frame = 3 
Query:  108 EMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDT-EKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKT-IEELLPFAF 470
            E++    +++  AYCPYS F VGA+IL   G I +GCN+EN SY   VCAE TA  +AV++   +F A+ V  D  + F+ PCG CRQ L EF T+    + L K + S  KT + +LLP AF
Sbjct:    5 ELVAKCLQAREMAYCPYSGFPVGAAILTTGGAIVTGCNVENASYGLTVCAERTAIQRAVAEGYRRFTAIAVTCDIKDSFVGPCGACRQVLMEFGTE--WDVYLTKPDGSYRKTSLRDLLPLAF 125
[Close]
BLAST of Cytidine deaminase vs. Ensembl Mouse
Match: Cda (cytidine deaminase [Source:MGI Symbol;Acc:MGI:1919519])

HSP 1 Score: 119.398 bits (298), Expect = 3.972e-34
Identity = 58/136 (42.65%), Postives = 88/136 (64.71%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVAND-TEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFD-EDFKE 488
            + PE +  ++  + ++K +AYCPYS+F VGA++L  +G+I+SGCNIEN  YP GVCAE TA  KA+S+    F A+ +++D  E+FI PCG CRQ + EF T +  +           +T++ELLP +F  ED ++
Sbjct:   10 VEPEHVQRLLLSSREAKKSAYCPYSRFPVGAALLTGDGRIFSGCNIENACYPLGVCAERTAIQKAISEGYKDFRAIAISSDLQEEFISPCGACRQVMREFGT-DWAVYMTKPDGTFVVRTVQELLPASFGPEDLQK 144
[Close]
BLAST of Cytidine deaminase vs. UniProt/SwissProt
Match: sp|P56389|CDD_MOUSE (Cytidine deaminase OS=Mus musculus OX=10090 GN=Cda PE=1 SV=2)

HSP 1 Score: 119.398 bits (298), Expect = 2.778e-33
Identity = 58/136 (42.65%), Postives = 88/136 (64.71%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVAND-TEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFD-EDFKE 488
            + PE +  ++  + ++K +AYCPYS+F VGA++L  +G+I+SGCNIEN  YP GVCAE TA  KA+S+    F A+ +++D  E+FI PCG CRQ + EF T +  +           +T++ELLP +F  ED ++
Sbjct:   10 VEPEHVQRLLLSSREAKKSAYCPYSRFPVGAALLTGDGRIFSGCNIENACYPLGVCAERTAIQKAISEGYKDFRAIAISSDLQEEFISPCGACRQVMREFGT-DWAVYMTKPDGTFVVRTVQELLPASFGPEDLQK 144
[Close]
BLAST of Cytidine deaminase vs. UniProt/SwissProt
Match: sp|P32320|CDD_HUMAN (Cytidine deaminase OS=Homo sapiens OX=9606 GN=CDA PE=1 SV=2)

HSP 1 Score: 116.316 bits (290), Expect = 3.735e-32
Identity = 58/138 (42.03%), Postives = 85/138 (61.59%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTE-KFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFD-EDFKEDK 494
            + PE + +++  + ++K +AYCPYS F VGA++L   G+I+ GCNIEN  YP G+CAE TA  KAVS+    F A+ +A+D +  FI PCG CRQ + EF T N  +            T++ELLP +F  ED ++ +
Sbjct:   10 LKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGT-NWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ 146
[Close]
BLAST of Cytidine deaminase vs. UniProt/SwissProt
Match: sp|P19079|CDD_BACSU (Cytidine deaminase OS=Bacillus subtilis (strain 168) OX=224308 GN=cdd PE=1 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 4.271e-32
Identity = 60/131 (45.80%), Postives = 83/131 (63.36%), Query Frame = 3 
Query:  105 NEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAF-DEDFKEDK 494
             E+I  A K++  AY PYSKF+VGA++L  +GK+Y GCNIEN +Y    CAE TA  KAVS+   +F  + VA DT   + PCG CRQ +SE  TK++ ++  N   +    T+EELLP AF  ED  +++
Sbjct:    4 QELITEALKARDMAYAPYSKFQVGAALLTKDGKVYRGCNIENAAYSMCNCAERTALFKAVSEGDTEFQMLAVAADTPGPVSPCGACRQVISELCTKDVIVVLTNLQGQIKEMTVEELLPGAFSSEDLHDER 134
[Close]
BLAST of Cytidine deaminase vs. UniProt/SwissProt
Match: sp|Q9S3M0|CDD_SPOPS (Cytidine deaminase OS=Sporosarcina psychrophila OX=1476 GN=cdd PE=3 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 2.756e-29
Identity = 55/126 (43.65%), Postives = 76/126 (60.32%), Query Frame = 3 
Query:  102 LNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDED 479
            + ++I  + K++  AY PYSKF VGA++L  +G IY GCNIEN +Y    CAE TA  KAVSD    F A+ V  DTE  + PCG CRQ ++EF   +M +   N     +  T+ +LLP AF ++
Sbjct:    3 VEKLIAESKKAREQAYVPYSKFPVGAALLAEDGTIYHGCNIENSAYSMTNCAERTAFFKAVSDGVRSFKALAVVADTEGPVSPCGACRQVIAEFCNGSMPVYLTNLKGDIEETTVAKLLPGAFSKE 128
[Close]
BLAST of Cytidine deaminase vs. UniProt/SwissProt
Match: sp|Q54I82|CDD_DICDI (Probable cytidine deaminase OS=Dictyostelium discoideum OX=44689 GN=cda PE=3 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 1.503e-27
Identity = 54/132 (40.91%), Postives = 81/132 (61.36%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVAND-TEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDED 479
            MN E L + I  A  S+  A+CPYS F++GA++L   GKI++G N+EN SY   +CAE TA +KAVS+    F  +VVA+D  ++FI PCG CRQF  EF   + +++ +     +   +  +LLP  F ++
Sbjct:    1 MNQEELEKCIDAAQNSQQYAHCPYSHFRIGAALLTSCGKIFTGVNVENSSYGLTICAERTAYTKAVSEGYKSFKGIVVASDLKDRFITPCGACRQFGVEFG--DFEVVCVKPDRSTFKSSTHKLLPGLFSQE 130
[Close]
BLAST of Cytidine deaminase vs. TrEMBL
Match: S2JZ40 (Cytidine deaminase OS=Mucor circinelloides f. circinelloides (strain 1006PhL) OX=1220926 GN=HMPREF1544_08147 PE=3 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 8.476e-38
Identity = 62/131 (47.33%), Postives = 87/131 (66.41%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDED 479
            ++ E   E+  +A  ++ T+Y PYSKF+VGA+++  +G ++ GCN+EN SY   +CAE TA  KAVS+  LKF A+ V+ D + FI PCG CRQF+SEF +K+M +  LNK         E+LLPFAFD D
Sbjct:    6 LSKEEQKELFNLALTARETSYSPYSKFRVGAALMATDGTLFKGCNVENASYGAAICAERTAFVKAVSEGHLKFRALAVSTDQDDFISPCGICRQFISEFVSKDMPVFFLNKHGDHREYKFEQLLPFAFDYD 136
[Close]
BLAST of Cytidine deaminase vs. TrEMBL
Match: A0A0C9MIE8 (Cytidine deaminase OS=Mucor ambiguus OX=91626 GN=MAM1_0010c01132 PE=3 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 1.492e-37
Identity = 61/131 (46.56%), Postives = 88/131 (67.18%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDED 479
            ++ E   ++  +A  ++ T+Y PYSKF+VGA+++  +G ++ GCN+EN SY   +CAE TA  KAVS+  LKF A+ V+ D + FI PCG CRQF+SEF +K+M +  LNK  +      E+LLPFAFD D
Sbjct:    6 LSKEEQEKLFSLALTARETSYSPYSKFRVGAALMATDGTLFKGCNVENASYGAAICAERTAFVKAVSEGYLKFHALAVSTDQDDFISPCGICRQFISEFVSKDMPVFFLNKHGEHREYKFEQLLPFAFDYD 136
[Close]
BLAST of Cytidine deaminase vs. TrEMBL
Match: A0A1U7SSZ6 (Cytidine deaminase OS=Tarsius syrichta OX=1868482 GN=CDA PE=3 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 1.443e-36
Identity = 64/133 (48.12%), Postives = 90/133 (67.67%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTE-KFIRPCGQCRQFLSEFSTKNMQIISLNKTNKS-DTKTIEELLPFAFDED 479
            M PE L +++  + ++K  AYCPYS F VGA++L  +GKI+SGCN+EN SYP G+CAE TA  KAVS+    F+A+ V++D +  FI PCG CRQ + EF TK    + + K + + D KT++ELLP +F  D
Sbjct:   10 MKPEQLQQLLLASREAKKAAYCPYSHFPVGAALLTRDGKIFSGCNVENASYPLGICAERTAIQKAVSEGSKDFLAIAVSSDVQDDFITPCGACRQVMREFGTK--WAVYMTKPDGTYDVKTVQELLPASFGPD 140
[Close]
BLAST of Cytidine deaminase vs. TrEMBL
Match: A0A1H9LLE0 (Cytidine deaminase OS=Gracilibacillus ureilyticus OX=531814 GN=SAMN04487944_101307 PE=3 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 8.449e-36
Identity = 64/122 (52.46%), Postives = 84/122 (68.85%), Query Frame = 3 
Query:  108 EMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFD 473
            E+I +A K++  AY PYSKF+VGA++L  +GK+YSGCNIEN +YP  VCAE TA  KA+SD    F  + V  DTE+ + PCG CRQ LSEF  K+  I + N     +T T+EELLPF+F+
Sbjct:    5 ELINLAKKAREKAYTPYSKFRVGAALLMKSGKVYSGCNIENAAYPVTVCAERTAIFKAISDGEYDFEEMAVVADTERPVPPCGSCRQVLSEFFPKDSLIHTSNLNGNVNTVTMEELLPFSFE 126
[Close]
BLAST of Cytidine deaminase vs. TrEMBL
Match: A0A367KY17 (Cytidine deaminase OS=Rhizopus stolonifer OX=4846 GN=CU098_013926 PE=3 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 4.312e-35
Identity = 60/128 (46.88%), Postives = 86/128 (67.19%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAF 470
            +  E+   + + A K+K T+Y PYSKF+VGA++L  +G +++GCN+EN SY   +CAE TA  KAVS+   KF A+ +++D E+FI PCG CRQF+SEF +  + +  LN   +S   T  ELLPFAF
Sbjct:    8 LTTELKQSLFEKALKAKETSYSPYSKFRVGAALLTEDGTLFTGCNVENASYGAAICAERTAFVKAVSEGHRKFTALAISSDIEEFITPCGICRQFVSEFVSSKLLVFFLNIKGESKEYTFGELLPFAF 135
[Close]
BLAST of Cytidine deaminase vs. Ensembl Cavefish
Match: zgc:103586 (zgc:103586 [Source:ZFIN;Acc:ZDB-GENE-041114-88])

HSP 1 Score: 103.219 bits (256), Expect = 3.557e-28
Identity = 56/126 (44.44%), Postives = 77/126 (61.11%), Query Frame = 3 
Query:   99 ILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDT-EKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKT-IEELLPFAF 470
            ++ E++    +++  AYCPYS+F VGA+IL   G I +GCN+EN SY   VCAE TA  +AV++    F A+ V  D  + F+ PCG CRQ L EF T+    I L K + S  KT + +LLP AF
Sbjct:    4 MIAELVAKCLQAREMAYCPYSRFPVGAAILTSGGTIITGCNVENASYGLTVCAERTAIQRAVAEGHRSFTAIAVTCDIKDSFVGPCGACRQVLMEFGTE--WDIYLTKPDGSYKKTSLRDLLPLAF 127
[Close]
BLAST of Cytidine deaminase vs. Ensembl Cavefish
Match: cdaa (cytidine deaminase [Source:NCBI gene;Acc:111194067])

HSP 1 Score: 102.834 bits (255), Expect = 9.516e-28
Identity = 55/133 (41.35%), Postives = 84/133 (63.16%), Query Frame = 3 
Query:  105 NEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVAND-TEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKS-DTKTIEELLPFAFD-EDFKEDK 494
             +++  + ++K  +Y PYS F+VGA++L  + ++Y+GCN+EN     G+CAE TA  KAVS+    F A+ VA+D  + +I PCG CRQF+ EF  +    + L+K + S   KT+EELLP +F  ED +  K
Sbjct:    9 QDLVSRSQEAKGFSYSPYSSFRVGAALLTTDQQLYTGCNVENACNNLGICAERTAICKAVSEGHRSFKAIAVASDMMDHYISPCGGCRQFMREFGLQ--WDVYLSKPDGSFIKKTVEELLPVSFGPEDLRRKK 139
[Close]
BLAST of Cytidine deaminase vs. Ensembl Cavefish
Match: cdab (cytidine deaminase b [Source:ZFIN;Acc:ZDB-GENE-040426-1911])

HSP 1 Score: 77.411 bits (189), Expect = 1.964e-18
Identity = 43/94 (45.74%), Postives = 59/94 (62.77%), Query Frame = 3 
Query:  204 IYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDT-EKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTK-TIEELLPFAFDED 479
            ++  CN+EN  Y  G+CAE TA SKAVS+    F A+ +A+D  E+FI PCG CRQF+ EF       + L+K + S  + T+EELLP +F  D
Sbjct:    4 VFYSCNVENACYNLGICAERTAISKAVSEGYRDFKAIAIASDLCEQFISPCGGCRQFMREFGAT--WDVYLSKPDGSYVEMTVEELLPGSFGPD 95
[Close]
BLAST of Cytidine deaminase vs. Ensembl Cavefish
Match: cdab (cytidine deaminase b [Source:ZFIN;Acc:ZDB-GENE-040426-1911])

HSP 1 Score: 78.5666 bits (192), Expect = 2.105e-18
Identity = 44/92 (47.83%), Postives = 58/92 (63.04%), Query Frame = 3 
Query:  210 SGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDT-EKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTK-TIEELLPFAFDED 479
             GCN+EN  Y  G+CAE TA SKAVS+    F A+ +A+D  E+FI PCG CRQF+ EF       + L+K + S  + T+EELLP +F  D
Sbjct:   47 QGCNVENACYNLGICAERTAISKAVSEGYRDFKAIAIASDLCEQFISPCGGCRQFMREFGA--TWDVYLSKPDGSYVEMTVEELLPGSFGPD 136
[Close]
BLAST of Cytidine deaminase vs. Ensembl Cavefish
Match: cdab (cytidine deaminase b [Source:ZFIN;Acc:ZDB-GENE-040426-1911])

HSP 1 Score: 77.411 bits (189), Expect = 2.469e-18
Identity = 44/94 (46.81%), Postives = 59/94 (62.77%), Query Frame = 3 
Query:  204 IYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDT-EKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTK-TIEELLPFAFDED 479
            +Y  CN+EN  Y  G+CAE TA SKAVS+    F A+ +A+D  E+FI PCG CRQF+ EF       + L+K + S  + T+EELLP +F  D
Sbjct:   20 LYRCCNVENACYNLGICAERTAISKAVSEGYRDFKAIAIASDLCEQFISPCGGCRQFMREFGAT--WDVYLSKPDGSYVEMTVEELLPGSFGPD 111
[Close]
BLAST of Cytidine deaminase vs. Ensembl Yeast
Match: CDD1 (Cytidine deaminase; catalyzes the modification of cytidine to uridine in vitro but native RNA substrates have not been identified, localizes to both the nucleus and cytoplasm [Source:SGD;Acc:S000004235])

HSP 1 Score: 86.6557 bits (213), Expect = 1.771e-22
Identity = 50/126 (39.68%), Postives = 76/126 (60.32%), Query Frame = 3 
Query:  102 LNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAV-SDDCLKFIAVVVANDTE-KFIRPCGQCRQFLSEFSTKNMQIISLNKT-NKSDTKTIEELLPFAF 470
            L  + + A K+   +Y PYS F+VG SIL  N  I++G N+EN SY   +CAE +A  + + +     +  +V+  D+E + + PCG CRQF++EF  K+  I+ LN T ++S   T+ ELLP AF
Sbjct:   11 LEALKRAALKACELSYSPYSHFRVGCSILTNNDVIFTGANVENASYSNCICAERSAMIQVLMAGHRSGWKCMVICGDSEDQCVSPCGVCRQFINEFVVKDFPIVMLNSTGSRSKVMTMGELLPMAF 136
[Close]
BLAST of Cytidine deaminase vs. Ensembl Nematostella
Match: EDO37512 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFK0])

HSP 1 Score: 102.449 bits (254), Expect = 3.954e-28
Identity = 50/123 (40.65%), Postives = 78/123 (63.41%), Query Frame = 3 
Query:  102 LNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAF 470
            + ++IK   K+K  +Y PYSKF+VG+++L  + +I++GCN+EN SY  G+CAE TA  KAVS+    F A+ V  D   +  PCG CRQF++EF   ++++   +  +      I++LLP AF
Sbjct:   17 IQDLIKQCFKAKEFSYSPYSKFRVGSAVLTNDNRIFTGCNVENASYGIGICAERTALVKAVSEGFRGFKAIAVCTDVAAYTGPCGACRQFIAEFGL-DIEVYMCSTDHSYQLLLIKDLLPRAF 138
[Close]
BLAST of Cytidine deaminase vs. Ensembl Medaka
Match: cdab (cytidine deaminase [Source:NCBI gene;Acc:101171740])

HSP 1 Score: 120.553 bits (301), Expect = 3.714e-34
Identity = 60/139 (43.17%), Postives = 92/139 (66.19%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDT-EKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTK-TIEELLPFAFD-EDFKEDK 494
            ++PE +  +I  + ++K  AYCPYS+F+VGA++L ++ ++++GCN+EN  Y  G+CAE  A +KAVS+    F A+ VA+D  + F+ PCG CRQF+ EF T     + L+  + S  K T+EELLPF+F  ED  + K
Sbjct:   45 LSPETVQRLIFQSQEAKKKAYCPYSQFRVGAALLTIDNRVFTGCNVENACYNLGMCAERNAMAKAVSEGHRNFKAIAVASDVRDHFVFPCGGCRQFMREFGTD--WDVYLSHPDGSHRKMTVEELLPFSFGPEDLSKKK 181
[Close]
BLAST of Cytidine deaminase vs. Planmine SMEST
Match: SMESG000064137.1 (SMESG000064137.1)

HSP 1 Score: 271.552 bits (693), Expect = 1.706e-94
Identity = 133/136 (97.79%), Postives = 133/136 (97.79%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDEDFKEDK 494
            MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAA KAVSDDCLKF AVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDEDF EDK
Sbjct:    1 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAACKAVSDDCLKFTAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDEDFNEDK 136
[Close]
BLAST of Cytidine deaminase vs. Planmine SMEST
Match: SMESG000064135.1 (SMESG000064135.1)

HSP 1 Score: 271.552 bits (693), Expect = 1.863e-94
Identity = 133/136 (97.79%), Postives = 133/136 (97.79%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDEDFKEDK 494
            MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAA KAVSDDCLKFIAVVVA DTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLP AFDEDFKEDK
Sbjct:    1 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAACKAVSDDCLKFIAVVVATDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPLAFDEDFKEDK 136
[Close]
BLAST of Cytidine deaminase vs. Planmine SMEST
Match: SMESG000056181.1 (SMESG000056181.1)

HSP 1 Score: 171.014 bits (432), Expect = 9.696e-55
Identity = 80/135 (59.26%), Postives = 104/135 (77.04%), Query Frame = 3 
Query:   87 MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFDEDFKED 491
            M  ++L+ +I+VA  +K+ AYCPYS F+VG +ILG N  IYSGCNIEN SYPCG CAEVTAA+KAVSD CL+F  +VVA DT+ F+RPCG+CRQFLSEF T    +IS+N  N+ D  T E+L P AF+E+F+++
Sbjct:    1 MCEDLLDNLIQVAVDAKSLAYCPYSHFRVGCAILGRNKTIYSGCNIENSSYPCGCCAEVTAAAKAVSDKCLEFSVIVVATDTDYFVRPCGKCRQFLSEFRTTETIVISVNILNRFDVITFEKLFPGAFNEEFEKN 135
[Close]
BLAST of Cytidine deaminase vs. Planmine SMEST
Match: SMESG000010242.1 (SMESG000010242.1)

HSP 1 Score: 99.3673 bits (246), Expect = 9.176e-27
Identity = 51/125 (40.80%), Postives = 72/125 (57.60%), Query Frame = 3 
Query:   99 ILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCSYPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFSTKNMQIISLNKTNKSDTKTIEELLPFAFD 473
            I  ++I  A   K+ AYCPYSKF VGA++L    +I +G N+EN S   G CAE  A  KA+S  C    A+ ++ + E+FI PCG C Q ++EF  K   I S+NK ++     ++EL P  F 
Sbjct:   14 IERKLIDAAAHVKSNAYCPYSKFAVGAAVLTNTDEIITGVNVENASASNGCCAEKVAVVKAISKGCKSLKALAISTNFEEFIWPCGSCLQVVAEFVPKEFPIYSINKLHEIKEAHLKELFPKQFH 138
The following BLAST results are available for this feature:
BLAST of Cytidine deaminase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CDA7.777e-3342.03cytidine deaminase [Source:HGNC Symbol;Acc:HGNC:17... [more]
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BLAST of Cytidine deaminase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
cdd-24.705e-2739.85Cytidine deaminase [Source:UniProtKB/TrEMBL;Acc:Q... [more]
cdd-15.320e-2036.76Cytidine deaminase [Source:UniProtKB/TrEMBL;Acc:Q... [more]
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BLAST of Cytidine deaminase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG83604.394e-2843.48gene:FBgn0032001 transcript:FBtr0332414[more]
CG83604.394e-2843.48gene:FBgn0032001 transcript:FBtr0089935[more]
CG83532.085e-2443.52gene:FBgn0032002 transcript:FBtr0332415[more]
CG83532.085e-2443.52gene:FBgn0032002 transcript:FBtr0079593[more]
CG83499.588e-2144.55gene:FBgn0032003 transcript:FBtr0079594[more]
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BLAST of Cytidine deaminase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
cdaa5.659e-3545.45cytidine deaminase a [Source:ZFIN;Acc:ZDB-GENE-170... [more]
cdab9.674e-3245.52cytidine deaminase b [Source:ZFIN;Acc:ZDB-GENE-040... [more]
zgc:1035861.082e-2744.72zgc:103586 [Source:ZFIN;Acc:ZDB-GENE-041114-88][more]
zgc:1035861.082e-2744.72zgc:103586 [Source:ZFIN;Acc:ZDB-GENE-041114-88][more]
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BLAST of Cytidine deaminase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cytidine deaminase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Cda3.972e-3442.65cytidine deaminase [Source:MGI Symbol;Acc:MGI:1919... [more]
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BLAST of Cytidine deaminase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P56389|CDD_MOUSE2.778e-3342.65Cytidine deaminase OS=Mus musculus OX=10090 GN=Cda... [more]
sp|P32320|CDD_HUMAN3.735e-3242.03Cytidine deaminase OS=Homo sapiens OX=9606 GN=CDA ... [more]
sp|P19079|CDD_BACSU4.271e-3245.80Cytidine deaminase OS=Bacillus subtilis (strain 16... [more]
sp|Q9S3M0|CDD_SPOPS2.756e-2943.65Cytidine deaminase OS=Sporosarcina psychrophila OX... [more]
sp|Q54I82|CDD_DICDI1.503e-2740.91Probable cytidine deaminase OS=Dictyostelium disco... [more]
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BLAST of Cytidine deaminase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
S2JZ408.476e-3847.33Cytidine deaminase OS=Mucor circinelloides f. circ... [more]
A0A0C9MIE81.492e-3746.56Cytidine deaminase OS=Mucor ambiguus OX=91626 GN=M... [more]
A0A1U7SSZ61.443e-3648.12Cytidine deaminase OS=Tarsius syrichta OX=1868482 ... [more]
A0A1H9LLE08.449e-3652.46Cytidine deaminase OS=Gracilibacillus ureilyticus ... [more]
A0A367KY174.312e-3546.88Cytidine deaminase OS=Rhizopus stolonifer OX=4846 ... [more]
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BLAST of Cytidine deaminase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zgc:1035863.557e-2844.44zgc:103586 [Source:ZFIN;Acc:ZDB-GENE-041114-88][more]
cdaa9.516e-2841.35cytidine deaminase [Source:NCBI gene;Acc:111194067... [more]
cdab1.964e-1845.74cytidine deaminase b [Source:ZFIN;Acc:ZDB-GENE-040... [more]
cdab2.105e-1847.83cytidine deaminase b [Source:ZFIN;Acc:ZDB-GENE-040... [more]
cdab2.469e-1846.81cytidine deaminase b [Source:ZFIN;Acc:ZDB-GENE-040... [more]
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BLAST of Cytidine deaminase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cytidine deaminase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
CDD11.771e-2239.68Cytidine deaminase; catalyzes the modification of ... [more]
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BLAST of Cytidine deaminase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO375123.954e-2840.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cytidine deaminase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cdab3.714e-3443.17cytidine deaminase [Source:NCBI gene;Acc:101171740... [more]
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BLAST of Cytidine deaminase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000064137.11.706e-9497.79SMESG000064137.1[more]
SMESG000064135.11.863e-9497.79SMESG000064135.1[more]
SMESG000056181.19.696e-5559.26SMESG000056181.1[more]
SMESG000010242.19.176e-2740.80SMESG000010242.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034331 ID=SMED30034331|Name=Cytidine deaminase|organism=Schmidtea mediterranea sexual|type=transcript|length=589bp
ATTTTAATGTAGTGCTTTGTTTAAATACGTGAATTATATTGTTAAAAAAA
TTAAATATTTTTTAAGTGTCTAAGTTATTTCTAATTATGAACCCAGAAAT
TTTGAATGAAATGATAAAAGTGGCAAATAAATCAAAAACTACCGCTTACT
GTCCTTACAGTAAGTTTAAAGTTGGTGCTTCCATTCTTGGAGTGAATGGT
AAAATTTATTCTGGCTGTAACATTGAAAATTGTTCGTATCCTTGTGGAGT
ATGTGCTGAAGTTACCGCCGCAAGCAAGGCAGTTTCTGATGATTGTTTGA
AATTTATTGCTGTAGTTGTTGCAAACGATACTGAAAAATTTATTCGTCCT
TGTGGGCAATGTCGGCAGTTTCTTTCTGAATTCAGCACAAAGAACATGCA
AATAATATCACTAAATAAAACGAACAAATCTGATACTAAAACTATTGAAG
AATTATTGCCATTTGCATTCGATGAAGATTTCAAAGAAGATAAATAGAAA
CAAAACATAATTAAAACTATATATTTGACATAAAATGTGATTAAAATAAA
AATATTTATTATTTGGTCAAAATAAAAGTTACAATTAAC
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protein sequence of SMED30034331-orf-1

>SMED30034331-orf-1 ID=SMED30034331-orf-1|Name=SMED30034331-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=137bp
MNPEILNEMIKVANKSKTTAYCPYSKFKVGASILGVNGKIYSGCNIENCS
YPCGVCAEVTAASKAVSDDCLKFIAVVVANDTEKFIRPCGQCRQFLSEFS
TKNMQIISLNKTNKSDTKTIEELLPFAFDEDFKEDK*
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protein sequence of SMED30034331-orf-2

>SMED30034331-orf-2 ID=SMED30034331-orf-2|Name=SMED30034331-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=128bp
VNCNFYFDQIINIFILITFYVKYIVLIMFCFYLSSLKSSSNANGNNSSIV
LVSDLFVLFSDIICMFFVLNSERNCRHCPQGRINFSVSFATTTAINFKQS
SETALLAAVTSAHTPQGYEQFSMLQPE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0016787hydrolase activity
GO:0046872metal ion binding
GO:0008270zinc ion binding
GO:0003824catalytic activity
GO:0042802identical protein binding
GO:0004126cytidine deaminase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0002075pigment cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR006262Cyt_deam_tetra
IPR002125CMP_dCMP_dom
IPR016193Cytidine_deaminase-like
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005829cytosol
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0006216cytidine catabolic process
GO:0006217deoxycytidine catabolic process
GO:0008655pyrimidine-containing compound salvage
GO:0009972cytidine deamination
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.40.140.10coord: 3..134
e-value: 8.4E-47
score: 160.6
NoneNo IPR availablePANTHERPTHR11644CYTIDINE DEAMINASEcoord: 6..131
NoneNo IPR availableCDDcd01283cytidine_deaminasecoord: 10..121
e-value: 7.13962E-33
score: 109.738
IPR006262Cytidine deaminase, homotetramericTIGRFAMTIGR01354TIGR01354coord: 8..131
e-value: 5.8E-40
score: 134.5
IPR002125Cytidine and deoxycytidylate deaminase domainPFAMPF00383dCMP_cyt_deam_1coord: 7..106
e-value: 2.0E-14
score: 53.3
IPR002125Cytidine and deoxycytidylate deaminase domainPROSITEPS51747CYT_DCMP_DEAMINASES_2coord: 4..131
score: 25.013
IPR016193Cytidine deaminase-likeSUPERFAMILYSSF53927Cytidine deaminase-likecoord: 6..131