5-hydroxytryptamine receptor

Overview
Name5-hydroxytryptamine receptor
Smed IDSMED30034320
Length (bp)1789
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of 5-hydroxytryptamine receptor (SMED30034320) t-SNE clustered cells

Violin plots show distribution of expression levels for 5-hydroxytryptamine receptor (SMED30034320) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 5-hydroxytryptamine receptor (SMED30034320) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for 5-hydroxytryptamine receptor (SMED30034320) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30034320

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30034320h1SMcG0001741 dd_Smed_v4_21060_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30034320h1SMcG0001741 dd_Smed_v4_21060_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Human
Match: HTR1A (5-hydroxytryptamine receptor 1A [Source:HGNC Symbol;Acc:HGNC:5286])

HSP 1 Score: 196.438 bits (498), Expect = 5.452e-56
Identity = 131/391 (33.50%), Postives = 216/391 (55.24%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLIN--SSVKSKYTCSLMEN-TVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRR 1503
            +GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ N+W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  +    I   W+I  +I++P    +   E +   +      C I+  + YT+ ST  AFY P++ M+++Y +IF+ A+ +IR+  +   +   D++        H      + + S  G+    N    V+SK   +L  N  VR       + V  +     +++  +  H+   S          S    N  +   E + K+ + RERK + T+GII   FILCW+PFF + LVLPFC + C +  ++ +++ WLGY N LLNP IY  F+++F+ AFK I+   + R+
Sbjct:   52 LGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDA-----CTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTR--------HGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEV-----HRVGNSKEHLPLPSEAGPTPCAPASFERKN--ERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 422
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Human
Match: HTR1B (5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287])

HSP 1 Score: 164.466 bits (415), Expect = 1.440e-44
Identity = 122/386 (31.61%), Postives = 187/386 (48.45%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGY-FYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQ----YLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            + N  V+  V   + L   +NYLI S+A+TDL+V+I VM +S +Y ++ RW LG   CDFW+ +D+  C+ASI HL  IALDRYW +T  +EY   RT  +    I  +W+ S+ I++P    F   + +  +EV     C++N+ +  YT+ STV AFY P + ++ +Y +I                             Y     R  +   + TG +     LI  S  S  + + + + V D           + SE    + VN V +    +L                     ++ K+   RERKA  T+GII   FI+CW+PFF ++LV+P C   C  H  I     WLGYLN L+NP IYT+ +++F+ AF  ++
Sbjct:   65 LSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPP---FFWRQAKAEEEV---SECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRI-----------------------------YVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPD-----------VPSESGSPVYVNQVKVRVSDAL--------------------LEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLI 384
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Human
Match: HTR1F (5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292])

HSP 1 Score: 154.836 bits (390), Expect = 2.660e-41
Identity = 123/385 (31.95%), Postives = 192/385 (49.87%), Query Frame = 1 
Query:  349 NILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINS---SVKSKYTCSLMENTVRDMKYA-DNI--SVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            N LV+ A+++ + L + +NYLI S+A+TD +VA+ VM  S VY +   W +G   CD W+  D+  C+ SI HL  IALDRY  +T  +EY   RT       I  +W+IS+ I++P  F  H+  T    E +IK   ++++ Y     ST  AFY P+  ++I+Y+KI                       Y++    +H    +  ++    G Q L+ S   S KS  T  ++E ++ D     D I  +V S+ SE K++ +                                 +R K+   RERKA  T+G+I   F++CW+PFF   LV+  C   C +   +S+ L WLGYLN L+NP IYTIF+++F+ AF+ ++
Sbjct:   41 NSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQ-GTSRDDECIIKHDHIVSTIY-----STFGAFYIPLALILILYYKI-----------------------YRAAKTLYHKRQASRIAKEEVNG-QVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKS--------------------------------WRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDK-CKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLV 362
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Human
Match: HTR1E (5-hydroxytryptamine receptor 1E [Source:HGNC Symbol;Acc:HGNC:5291])

HSP 1 Score: 146.362 bits (368), Expect = 3.123e-38
Identity = 116/378 (30.69%), Postives = 185/378 (48.94%), Query Frame = 1 
Query:  358 VVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRF-HFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMEN-TVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            V++A+   K L   +NYLI S+A+TDL+VA+ VM LS +Y + +RW LG   C+ W+  D+  C+ SI HL  IALDRYW +T  IEY   RT  +    IL++W IS+ I++P  F   HR  +    +  I+   +I     YT+ ST+ AFY P+  ++I+Y++I+  A                 S Y+      H  +R+T+S+               S  +C L +   V D   +D  +                 H +            + + P++       +R ++   RERKA   +G+I   FIL W+PFF   L++    +   V   ++  L WLGY+N L+NP +YT F+++F+ AFK ++
Sbjct:   43 VIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVI-----YTIYSTLGAFYIPLTLILILYYRIYHAA----------------KSLYQKRGSSRHLSNRSTDSQ--------------NSFASCKLTQTFCVSDFSTSDPTT------------EFEKFHAS------------IRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGL--SIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLI 359
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Human
Match: DRD2 (dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023])

HSP 1 Score: 127.872 bits (320), Expect = 2.456e-31
Identity = 111/383 (28.98%), Postives = 188/383 (49.09%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTIL--SIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEE--QRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            GN+LV +AV  EK L+  +NYLI+S+A+ DL+VA  VM      E+   W      CD ++  DVM C+ASI +L  I++DRY  V      + R  S+   T++   +W++S  I+ P  F  +  +         +  C+I +  F  + S++++FY P I  +++Y KI+ + +R+ +R         F +  ++  +      R  E E            +  S    S  + T+ D  +    S  + +S  K + N +     +++ +  ++T     MP   T+T  +   R K+  ++E+KA   + I+   FI+CW+PFF   ++   C   C + P++ S   WLGY+N  +NP IYT F+ EFR AF  IL
Sbjct:   51 GNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNAD---------QNECIIANPAF-VVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLK--EAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHS--TPDSPAKPEKNGHAKDHPKIAKIFEIQT-----MPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCD--CNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKIL 412
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Celegans
Match: ser-4 (SERotonin/octopamine receptor family; Serotonin receptor [Source:UniProtKB/TrEMBL;Acc:G5EGH0])

HSP 1 Score: 194.512 bits (493), Expect = 1.778e-55
Identity = 136/394 (34.52%), Postives = 202/394 (51.27%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNY-LILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGR-CLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEV-----TFDSKYKSICRYFHCCH-------RTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            +GN+ V+LA+++E++LR    Y LI S+A+ DL+V + V  L A + ++  W LG+  CDFWI  DV+ C+ASI HLV IALDRYW++T I Y  NRT  ++   +  IW  SL+I++     F   + + F + V+K   CLI+    Y + ST  AFY P+I ++ +YWKI + AK++ +R+R     +       D K   + +    C           ++   T G    I +  +   + S      R M   ++   +    E K      D    R                  + K     +   E+KRERKA  T+ IIT  F+ CW PFF +++  P CG  C + P++  V LWLGYLN  LNP IYT+FSQ+FR AFK I+
Sbjct:   67 IGNLFVILAIIMERDLRGRPQYYLIFSLAVADLLVGMIVTPLGAWFTVTGTWNLGVVVCDFWISVDVLVCTASILHLVAIALDRYWSITDICYVQNRTPKRITLMLAVIWFTSLLISLAP---FAGWKDEGFSDRVLKSHVCLISQQISYQVFSTATAFYIPLIAIICVYWKIMRAAKKRFKRERDRRTVIRPPPDAIDEKKAMMPKKSKKCPLPPAVVISDIQANGGTGGKTNSIKNPPRHNESSSSASEEERTMTQTNHAPGDVTTQETKI-----DEENGRSKP--------------GIVKRRRRTKESNEMKRERKAWRTLAIITGTFVACWTPFFLVSIYRPICG--CQISPVLEQVTLWLGYLNSALNPIIYTVFSQDFRAAFKRII 436
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Celegans
Match: ser-4 (SERotonin/octopamine receptor family; Serotonin receptor [Source:UniProtKB/TrEMBL;Acc:G5EGH0])

HSP 1 Score: 194.512 bits (493), Expect = 1.778e-55
Identity = 136/394 (34.52%), Postives = 202/394 (51.27%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNY-LILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGR-CLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEV-----TFDSKYKSICRYFHCCH-------RTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            +GN+ V+LA+++E++LR    Y LI S+A+ DL+V + V  L A + ++  W LG+  CDFWI  DV+ C+ASI HLV IALDRYW++T I Y  NRT  ++   +  IW  SL+I++     F   + + F + V+K   CLI+    Y + ST  AFY P+I ++ +YWKI + AK++ +R+R     +       D K   + +    C           ++   T G    I +  +   + S      R M   ++   +    E K      D    R                  + K     +   E+KRERKA  T+ IIT  F+ CW PFF +++  P CG  C + P++  V LWLGYLN  LNP IYT+FSQ+FR AFK I+
Sbjct:   67 IGNLFVILAIIMERDLRGRPQYYLIFSLAVADLLVGMIVTPLGAWFTVTGTWNLGVVVCDFWISVDVLVCTASILHLVAIALDRYWSITDICYVQNRTPKRITLMLAVIWFTSLLISLAP---FAGWKDEGFSDRVLKSHVCLISQQISYQVFSTATAFYIPLIAIICVYWKIMRAAKKRFKRERDRRTVIRPPPDAIDEKKAMMPKKSKKCPLPPAVVISDIQANGGTGGKTNSIKNPPRHNESSSSASEEERTMTQTNHAPGDVTTQETKI-----DEENGRSKP--------------GIVKRRRRTKESNEMKRERKAWRTLAIITGTFVACWTPFFLVSIYRPICG--CQISPVLEQVTLWLGYLNSALNPIIYTVFSQDFRAAFKRII 436
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Celegans
Match: ser-2 (Tyramine receptor Ser-2 [Source:UniProtKB/Swiss-Prot;Acc:O02213])

HSP 1 Score: 149.828 bits (377), Expect = 3.483e-39
Identity = 119/397 (29.97%), Postives = 194/397 (48.87%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAV-YEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTV-TRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY-------WXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTT------GDQYLINSSVKSKYTCSLMEN-TVRDMKYADNISVNSINSEIKY-QLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            VGN LVV+AV   + L+ + NY ++S+A +DL VAIFVM L  V +    +W LG+  C F+   D++ C++SI +L  IALDRYW +   I Y   RT   +   I+ +W++S++I+VP    ++      +QE +++  C +++   + + S   +F+ P++ M+++Y        +  +  + +    R  N E   D +  SI R      RT+      T      G   +   +  S    SL ++ T + MKY +N S      ++K  + N N   + R                         +R K+ V +E++A  T+ +I   F  CW+PFF   ++ PFC   C +H  +     WLGY+N  LNPF+Y I + EFR AFK IL
Sbjct:   73 VGNTLVVVAVFSYRPLKKVQNYFLVSLAASDLAVAIFVMPLHVVTFLAGGKWLLGVTVCQFFTTADILLCTSSILNLCAIALDRYWAIHNPINYAQKRTTKFVCIVIVIVWILSMLISVPPIIGWNN-----WQENMMEDSCGLSTEKAFVVFSAAGSFFLPLLVMVVVYVKIFISARQRIRTNRGRSALMRIQNAEGDDDYRKMSIKRASVESARTSSRVGEKTPLVIADGQTTVTTLAAHSTDGGSLPKDETTKHMKYHNNGSCKVKVKDVKEDEGNPNPTAVLR-------------------------KREKISVAKEKRAAKTIAVIIFVFSFCWLPFFVAYVIRPFC-ETCKLHAKVEQAFTWLGYINSSLNPFLYGILNLEFRRAFKKIL 438
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Celegans
Match: ser-2 (Tyramine receptor Ser-2 [Source:UniProtKB/Swiss-Prot;Acc:O02213])

HSP 1 Score: 147.132 bits (370), Expect = 2.303e-38
Identity = 117/390 (30.00%), Postives = 189/390 (48.46%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAV-YEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTV-TRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY-------WXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKY-QLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            VGN LVV+AV   + L+ + NY ++S+A +DL VAIFVM L  V +    +W LG+  C F+   D++ C++SI +L  IALDRYW +   I Y   RT   +   I+ +W++S++I+VP    ++      +QE +++  C +++   + + S   +F+ P++ M+++Y        +  +  + +    R  N E   D +  SI R      RT+    S T    L              + T + MKY +N S      ++K  + N N   + R                         +R K+ V +E++A  T+ +I   F  CW+PFF   ++ PFC   C +H  +     WLGY+N  LNPF+Y I + EFR AFK IL
Sbjct:   70 VGNTLVVVAVFSYRPLKKVQNYFLVSLAASDLAVAIFVMPLHVVTFLAGGKWLLGVTVCQFFTTADILLCTSSILNLCAIALDRYWAIHNPINYAQKRTTKFVCIVIVIVWILSMLISVPPIIGWNN-----WQENMMEDSCGLSTEKAFVVFSAAGSFFLPLLVMVVVYVKIFISARQRIRTNRGRSALMRIQNAEGDDDYRKMSIKRASVESARTS----SRTDGGSLPK------------DETTKHMKYHNNGSCKVKVKDVKEDEGNPNPTAVLR-------------------------KREKISVAKEKRAAKTIAVIIFVFSFCWLPFFVAYVIRPFCET-CKLHAKVEQAFTWLGYINSSLNPFLYGILNLEFRRAFKKIL 412
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Celegans
Match: ser-2 (Tyramine receptor Ser-2 [Source:UniProtKB/Swiss-Prot;Acc:O02213])

HSP 1 Score: 146.747 bits (369), Expect = 2.653e-38
Identity = 117/390 (30.00%), Postives = 189/390 (48.46%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAV-YEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTV-TRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY-------WXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKY-QLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            VGN LVV+AV   + L+ + NY ++S+A +DL VAIFVM L  V +    +W LG+  C F+   D++ C++SI +L  IALDRYW +   I Y   RT   +   I+ +W++S++I+VP    ++      +QE +++  C +++   + + S   +F+ P++ M+++Y        +  +  + +    R  N E   D +  SI R      RT+    S T    L              + T + MKY +N S      ++K  + N N   + R                         +R K+ V +E++A  T+ +I   F  CW+PFF   ++ PFC   C +H  +     WLGY+N  LNPF+Y I + EFR AFK IL
Sbjct:   62 VGNTLVVVAVFSYRPLKKVQNYFLVSLAASDLAVAIFVMPLHVVTFLAGGKWLLGVTVCQFFTTADILLCTSSILNLCAIALDRYWAIHNPINYAQKRTTKFVCIVIVIVWILSMLISVPPIIGWNN-----WQENMMEDSCGLSTEKAFVVFSAAGSFFLPLLVMVVVYVKIFISARQRIRTNRGRSALMRIQNAEGDDDYRKMSIKRASVESARTS----SRTDGGSLPK------------DETTKHMKYHNNGSCKVKVKDVKEDEGNPNPTAVLR-------------------------KREKISVAKEKRAAKTIAVIIFVFSFCWLPFFVAYVIRPFCET-CKLHAKVEQAFTWLGYINSSLNPFLYGILNLEFRRAFKKIL 404
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Fly
Match: 5-HT1A (gene:FBgn0004168 transcript:FBtr0474126)

HSP 1 Score: 155.221 bits (391), Expect = 2.049e-39
Identity = 69/175 (39.43%), Postives = 110/175 (62.86%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRF------HFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYW 849
            +GN+ V+ A++LE+NL+N++NYL+ S+A+ DL VA  VM L AVYEIS  W LG   CD W   DV+ C+ASI HLV IA+DRYW VT I+Y H+RT +++   I  +W  ++++++  +F      +  R+E Q         +C+++    Y + +T   FY P++ ++ +YW
Sbjct:  242 IGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISQGWILGPELCDIWTSCDVLCCTASILHLVAIAVDRYWAVTNIDYIHSRTSNRVFMMIFCVWTAAVIVSLAPQFGWKDPDYLQRIEQQ---------KCMVSQDVSYQVFATCCTFYVPLLVILALYW 407

HSP 2 Score: 87.8113 bits (216), Expect = 1.146e-17
Identity = 48/97 (49.48%), Postives = 65/97 (67.01%), Query Frame = 1 
Query: 1204 NLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYY 1494
            N  + + +++  +E KRERKA  T+ IIT  F++CW+PFF + L +P C A C +   ++S+ LWLGY N  LNP IYTIFS EFR AFK IL G +
Sbjct:  729 NPMQKVNKRKETLEAKRERKAAKTLAIITGAFVVCWLPFFVMALTMPLCAA-CQISDSVASLFLWLGYFNSTLNPVIYTIFSPEFRQAFKRILFGGH 824
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Fly
Match: 5-HT1A (gene:FBgn0004168 transcript:FBtr0086577)

HSP 1 Score: 155.221 bits (391), Expect = 2.135e-39
Identity = 69/175 (39.43%), Postives = 110/175 (62.86%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRF------HFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYW 849
            +GN+ V+ A++LE+NL+N++NYL+ S+A+ DL VA  VM L AVYEIS  W LG   CD W   DV+ C+ASI HLV IA+DRYW VT I+Y H+RT +++   I  +W  ++++++  +F      +  R+E Q         +C+++    Y + +T   FY P++ ++ +YW
Sbjct:  242 IGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISQGWILGPELCDIWTSCDVLCCTASILHLVAIAVDRYWAVTNIDYIHSRTSNRVFMMIFCVWTAAVIVSLAPQFGWKDPDYLQRIEQQ---------KCMVSQDVSYQVFATCCTFYVPLLVILALYW 407

HSP 2 Score: 87.8113 bits (216), Expect = 1.040e-17
Identity = 48/97 (49.48%), Postives = 65/97 (67.01%), Query Frame = 1 
Query: 1204 NLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYY 1494
            N  + + +++  +E KRERKA  T+ IIT  F++CW+PFF + L +P C A C +   ++S+ LWLGY N  LNP IYTIFS EFR AFK IL G +
Sbjct:  729 NPMQKVNKRKETLEAKRERKAAKTLAIITGAFVVCWLPFFVMALTMPLCAA-CQISDSVASLFLWLGYFNSTLNPVIYTIFSPEFRQAFKRILFGGH 824
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Fly
Match: 5-HT1B (gene:FBgn0263116 transcript:FBtr0330055)

HSP 1 Score: 152.14 bits (383), Expect = 3.293e-39
Identity = 68/169 (40.24%), Postives = 109/169 (64.50%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYW 849
            +GN+ V+ A++LE+NL+N++NYL+ S+A+ DL VA  VM L AVYEISN W LG   CD W   DV+ C+ASI HLV IA DRYWTVT I+Y + RT  ++   I  +W  +L++++  +F +   +   + + + +  C+++    Y + +T   FY P++ ++ +YW
Sbjct:  106 IGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTNIDYNNLRTPRRVFLMIFCVWFAALIVSLAPQFGWKDPD---YMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYW 271

HSP 2 Score: 82.4185 bits (202), Expect = 3.239e-16
Identity = 47/95 (49.47%), Postives = 63/95 (66.32%), Query Frame = 1 
Query: 1204 NLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTG 1488
            N  + + ++R  +E KRERKA  T+ IIT  F++CW+PFF + L +  C   C +H  ++S+ LWLGY N  LNP IYTIF+ EFR AFK IL G
Sbjct:  457 NPHQKLAKRRQLLEAKRERKAAQTLAIITGAFVICWLPFFVMALTMSLC-KECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRILFG 550
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Fly
Match: 5-HT1B (gene:FBgn0263116 transcript:FBtr0086599)

HSP 1 Score: 152.525 bits (384), Expect = 4.042e-39
Identity = 68/169 (40.24%), Postives = 109/169 (64.50%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYW 849
            +GN+ V+ A++LE+NL+N++NYL+ S+A+ DL VA  VM L AVYEISN W LG   CD W   DV+ C+ASI HLV IA DRYWTVT I+Y + RT  ++   I  +W  +L++++  +F +   +   + + + +  C+++    Y + +T   FY P++ ++ +YW
Sbjct:  106 IGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTNIDYNNLRTPRRVFLMIFCVWFAALIVSLAPQFGWKDPD---YMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYW 271

HSP 2 Score: 83.1889 bits (204), Expect = 2.367e-16
Identity = 47/95 (49.47%), Postives = 63/95 (66.32%), Query Frame = 1 
Query: 1204 NLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTG 1488
            N  + + ++R  +E KRERKA  T+ IIT  F++CW+PFF + L +  C   C +H  ++S+ LWLGY N  LNP IYTIF+ EFR AFK IL G
Sbjct:  512 NPHQKLAKRRQLLEAKRERKAAQTLAIITGAFVICWLPFFVMALTMSLC-KECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRILFG 605
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Fly
Match: 5-HT1B (gene:FBgn0263116 transcript:FBtr0330056)

HSP 1 Score: 152.525 bits (384), Expect = 4.517e-39
Identity = 68/169 (40.24%), Postives = 109/169 (64.50%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYW 849
            +GN+ V+ A++LE+NL+N++NYL+ S+A+ DL VA  VM L AVYEISN W LG   CD W   DV+ C+ASI HLV IA DRYWTVT I+Y + RT  ++   I  +W  +L++++  +F +   +   + + + +  C+++    Y + +T   FY P++ ++ +YW
Sbjct:  106 IGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTNIDYNNLRTPRRVFLMIFCVWFAALIVSLAPQFGWKDPD---YMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYW 271

HSP 2 Score: 83.1889 bits (204), Expect = 2.335e-16
Identity = 47/95 (49.47%), Postives = 63/95 (66.32%), Query Frame = 1 
Query: 1204 NLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTG 1488
            N  + + ++R  +E KRERKA  T+ IIT  F++CW+PFF + L +  C   C +H  ++S+ LWLGY N  LNP IYTIF+ EFR AFK IL G
Sbjct:  512 NPHQKLAKRRQLLEAKRERKAAQTLAIITGAFVICWLPFFVMALTMSLC-KECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRILFG 605
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Zebrafish
Match: htr1aa (5-hydroxytryptamine (serotonin) receptor 1A a [Source:ZFIN;Acc:ZDB-GENE-071203-1])

HSP 1 Score: 186.422 bits (472), Expect = 1.055e-52
Identity = 123/383 (32.11%), Postives = 199/383 (51.96%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMP--YNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            +GN  V+ A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ N+W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  +    I   W+I   I++P    + + E +   +      C I+  + YT+ ST  AFY P+I M+++Y           R  R   + +    K     +    C   + + F    +  +  +  +S   C+     +++    ++  +  + S  K  L                 +L  +  P   N  +   E + KV + RERK + T+GII   FI CW+PFF + LVLPFC   C +   + +V+ WLGY N LLNP IY  F+++F+ AFK IL
Sbjct:   44 LGNACVIAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQEMCDIFISLDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAILISLTWLIGFSISIPPMLGWRKPEDRADPDA-----CTISQDHGYTIYSTFGAFYIPLILMLVLY----------GRIFRAARFRIRKTVKKTEKAKIADKCLAVSPALFPRKANGEVGKTWRRSVEPCA--NGALKNSDDGESFEITEVQSISKNHL-----------------SLPNNPQPCFENRNEKNTEAKRKVALARERKTVKTLGIIMGTFIFCWLPFFIVALVLPFC-QDCFMPEWLGAVINWLGYSNSLLNPVIYAYFNKDFQNAFKKIL 391
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Zebrafish
Match: htr1ab (5-hydroxytryptamine (serotonin) receptor 1A b [Source:ZFIN;Acc:ZDB-GENE-090409-2])

HSP 1 Score: 182.956 bits (463), Expect = 3.060e-51
Identity = 118/388 (30.41%), Postives = 200/388 (51.55%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSI--NSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWR 1500
            GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ ++W LG   CD +I  D++ C++SI HL  IALDRYW +T  I+Y   RT+ +    I   W +   I++P             +++     C+I+   +YT+ ST  AFY P+I M+++Y                    +   ++++          +T             ++ ++  +    L +N    ++      VN    ++E    L + +VH    ++L    T     +  N  +   E + K+ + RERK + T+GII   FILCW+PFF   LV+PFC   C++   +  V+ WLGY N LLNP IY  F+++F+ AFK I+  ++ R
Sbjct:   52 GNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLDKWTLGQVTCDIFISLDILCCTSSILHLCAIALDRYWAITDPIDYMKKRTLKRAALLITVTWFVGFSISIPPMLIMKSQPKSRAEDMANPEACMISHDPWYTIYSTFCAFYIPLILMLVLYG------------------RIFKAARFR--------IRKTVRKPEKKRVKCLTVSPALFKRANGELSKNWKSAVEPKPAACVNGAIKHAEDGESLEIIEVHSNSKNNLPLPNTPNSVPLFENKHEKNTEAKRKLALARERKTVKTLGIIMGTFILCWLPFFIKALVMPFCPT-CVMPLWLQDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCHFCR 412
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Zebrafish
Match: htr1ab (5-hydroxytryptamine (serotonin) receptor 1A b [Source:ZFIN;Acc:ZDB-GENE-090409-2])

HSP 1 Score: 176.407 bits (446), Expect = 6.089e-49
Identity = 124/388 (31.96%), Postives = 207/388 (53.35%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLIN--SSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWR 1500
            GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ ++W LG   CD +I  D++ C++SI HL  IALDRYW +T  I+Y   RT+ +    I   W +   I++P       +++Q          C+I+   +YT+ ST  AFY P+I M+++Y         +I +  RF    T     K   +    C   + + F     +   N  S+V+ K   + +   ++  +  +++ +  ++S  K  L + +   +            V +      K  E +R K+ + RERK + T+GII   FILCW+PFF   LV+PFC   C++   +  V+ WLGY N LLNP IY  F+++F+ AFK I+  ++ R
Sbjct:   52 GNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLDKWTLGQVTCDIFISLDILCCTSSILHLCAIALDRYWAITDPIDYMKKRTLKRAALLITVTWFVGFSISIPPMLI---MKSQ-------PKTCMISHDPWYTIYSTFCAFYIPLILMLVLY--------GRIFKAARFRIRKTVRKPEKKRVK----CLTVSPALFKRANGELSKNWKSAVEPK-PAACVNGAIKHAEDGESLEIIEVHSNSKNNLPLPNTPNS------------VPLFENKHEKNTEAKR-KLALARERKTVKTLGIIMGTFILCWLPFFIKALVMPFCPT-CVMPLWLQDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCHFCR 402
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Zebrafish
Match: htr1ab (5-hydroxytryptamine (serotonin) receptor 1A b [Source:ZFIN;Acc:ZDB-GENE-090409-2])

HSP 1 Score: 176.407 bits (446), Expect = 6.089e-49
Identity = 124/388 (31.96%), Postives = 207/388 (53.35%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLIN--SSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWR 1500
            GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ ++W LG   CD +I  D++ C++SI HL  IALDRYW +T  I+Y   RT+ +    I   W +   I++P       +++Q          C+I+   +YT+ ST  AFY P+I M+++Y         +I +  RF    T     K   +    C   + + F     +   N  S+V+ K   + +   ++  +  +++ +  ++S  K  L + +   +            V +      K  E +R K+ + RERK + T+GII   FILCW+PFF   LV+PFC   C++   +  V+ WLGY N LLNP IY  F+++F+ AFK I+  ++ R
Sbjct:   52 GNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLDKWTLGQVTCDIFISLDILCCTSSILHLCAIALDRYWAITDPIDYMKKRTLKRAALLITVTWFVGFSISIPPMLI---MKSQ-------PKTCMISHDPWYTIYSTFCAFYIPLILMLVLY--------GRIFKAARFRIRKTVRKPEKKRVK----CLTVSPALFKRANGELSKNWKSAVEPK-PAACVNGAIKHAEDGESLEIIEVHSNSKNNLPLPNTPNS------------VPLFENKHEKNTEAKR-KLALARERKTVKTLGIIMGTFILCWLPFFIKALVMPFCPT-CVMPLWLQDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCHFCR 402
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Zebrafish
Match: HTR7 (5-hydroxytryptamine receptor 7 [Source:NCBI gene;Acc:100536080])

HSP 1 Score: 151.369 bits (381), Expect = 8.590e-40
Identity = 121/395 (30.63%), Postives = 185/395 (46.84%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYE-ISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEV-KRERKAIITVGIITCCFILCWMPFFTLTLVLPF-CGAYCIVHPI-ISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRRCIDR 1515
            GN+LVV++V   K L+  SNYLI+S+A+ DL VA+ VM   ++ + I  +W  G  +C+ +I  DVM C+ASI  L  I++DRY  +T+ + Y   ++   +   +LS+W++S  I +P  F +        Q V     CLI+    YT+ ST +AFY PM  M+I+Y++I               Y V  DS  K     F                                        K  D  S+N + + +K Q  V +                      + ++ ++  R  + + KRE+KA  T+GI+   F +CWMPFF L+   PF CG  C   P+ +   LLWLGY N L+NPFIY  F+++ R  + N++   Y  R I+R
Sbjct:   78 GNLLVVISVCFVKKLKQPSNYLIVSLAVADLSVAVVVMPFVSITDLIGGQWIFGRVFCNVFIAMDVMCCTASIMTLCVISIDRYLGITKPLTYPVRQSGKCMAKIVLSVWLLSASITLPPLFGWA-------QNVNDDNVCLISQDLGYTIYSTAVAFYIPMSVMLIMYYRI---------------YRVAKDSAAKHTIAGFP---------------------------------------KAEDEESMNCVTAALKLQREVEEC--------------------VSFSRLLKSDRKNISIFKREQKAAATLGIVVGAFAVCWMPFFLLSTARPFICGLQCSCVPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYHNLIRCRY--RNINR 389
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Xenopus
Match: ENSXETT00000046867.1 (5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled [Source:NCBI gene;Acc:100488829])

HSP 1 Score: 164.851 bits (416), Expect = 1.317e-44
Identity = 129/391 (32.99%), Postives = 207/391 (52.94%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVR---DMKYADNISVNS-INSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRR 1503
            GN  V+ A+ LE+ L+ ++NYLI S+A+TDL+V++ V+ ++A  ++ N+W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  +    I   W++   I++P    +   E +          C I+    YT+ ST  AFY P+I M+++Y KIF+ A+ +IR+  +   +        S+        R +  E S    +     +V+ K + + +   +R   D    + I V+  +NS+    L  N  H   ++  S  R  + +           + + KV + RERK + T+GII   FI CW+PFF + LVLPFC    + H ++  V+ WLGY N LLNP IY  F+++F+ AFK I+   + R+
Sbjct:   46 GNACVIAAIALERCLQTVANYLIGSLAVTDLMVSVLVLPMAAHNQVLNKWTLGQVTCDIFISLDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAVLISITWIVGFSISIPPMLGWRTPEDRSDPNA-----CKISEDPGYTIYSTFGAFYIPLILMLVLYGKIFKAARFRIRKTVKKAEKKKVADTCLSVSPAV--AERKSNGEPSKNWKR-----TVEPKPS-ACVNGAIRHGEDGAVLEIIEVHHYVNSKSHLDLP-NHAHDMAVAPCSEKRNDRAT-----------DAKRKVALARERKTVKTLGIIMGTFIFCWLPFFIVALVLPFCETCHMPH-LLFDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCKFCRQ 410
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Xenopus
Match: HTR1F (5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled [Source:NCBI gene;Acc:100494586])

HSP 1 Score: 154.451 bits (389), Expect = 3.451e-41
Identity = 114/380 (30.00%), Postives = 190/380 (50.00%), Query Frame = 1 
Query:  349 NILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYF-YTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            N LV+ A+++ + L + +NYLI S+A+TD +VA+ VM  S +Y +   W +G A CD W+  D+  C+ SI HL  IALDRY  +T  +EY   RT     F I  +W+IS+ I++P  F  H       Q +  +  C+I   +  +T+ ST  AFY P+  ++I+Y+KI                       YK+    +H   R+          Q L++++     T  + E +  D                 +  + + +HI       ++R  +V      + +    ++ K+   RERKA  T+G+I   F++CW+PFF   +++  C + C +   +S+ L WLGYLN L+NP IYTIF+++F+ AF+ ++
Sbjct:   41 NSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIMYIMKETWIMGQAICDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAAFMIAVVWIISIFISMPPLFWRH-------QALNKEDECIIKHDHIVFTIYSTFGAFYIPLALILILYYKI-----------------------YKAAKTLYH--KRSVSRVEREQNGQVLLDATT----TLCIAEKSFSD-----------------HSTDFDKIHI-------TVRNARV-----EMKQEKAYRKQKISSTRERKAATTLGLILGAFVICWLPFFVKEVIVNICES-CYISDDMSNFLTWLGYLNSLINPLIYTIFNEDFKKAFQKLM 354
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Xenopus
Match: HTR1E (5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled [Source:NCBI gene;Acc:100380026])

HSP 1 Score: 153.68 bits (387), Expect = 4.891e-41
Identity = 117/384 (30.47%), Postives = 179/384 (46.61%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYF-YTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMEN-TVRDMKYADNIS-VNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            V N  V+LA+   K L   +NYLI S+A+TD +VAI VM LS  Y + + W LG   C+ W+  D+  C+ SI HL  IALDRYW +T  IEY   RT+ +    IL++W IS+ I++P  F       +    + I  +C+I   +  YT+ ST  AFY P+  ++I+Y+                              R +H      +   S+       N S  S   C L +   V +   +D  +    +N+ ++     ND+ I                          +++ ++   RERKA   +G+I   FIL W+PFF   LV+      C V P ++  L WLGY+N L+NP +YT F+ +F+ AFK ++
Sbjct:   32 VLNSAVILAICTTKKLHQPANYLICSLAVTDFLVAILVMPLSITYIVMDTWTLGYVICEIWLSVDMTCCTCSILHLCVIALDRYWAITDAIEYARKRTVKRAGIMILTVWTISVFISIPPLFW------RNHHNINIPSKCIIQHDHLIYTIYSTCGAFYIPLTLILILYY------------------------------RIYHAAKNLYQKRGSSRHLSNRSNDSQNSFAHCKLTQTFCVSEFSTSDPTTEFEKMNASVRTPPYDNDIDI------------------------FGDRQQQISSSRERKAARILGLILGAFILSWLPFFIKELVVGI--QLCTVSPEVADFLTWLGYVNSLVNPLLYTSFNDDFKLAFKKLI 353
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Xenopus
Match: ADRA2B (adrenoceptor alpha 2B [Source:NCBI gene;Acc:100485811])

HSP 1 Score: 152.91 bits (385), Expect = 3.360e-40
Identity = 107/396 (27.02%), Postives = 202/396 (51.01%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQY---LINSSVKSKYTCSLME------NTVRDMK--YADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKT-IEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYY 1494
            GN+LV++AVL  ++L+   N  ++S+A  D++VA  ++  S   E+   W+ G  WC+ ++  DV+ C++SI HL  I+LDRYW+V++ IEY   RT  ++   IL +W ++ +I++P   +  + + Q       K  C +N   +Y L S++ +F+AP + M+++Y        R     +R N + + D K K +        RT +   +++  Q    +I+S  K+      +       ++ R+ +  ++++  +      +K+    N    A M ++++++   V +MP     + +   + K  + RE++    + ++   F+LCW PFF    +   C   C +   +     W+GY N  LNP IYTIF+Q+FR AF+ IL  ++
Sbjct:   34 GNVLVIIAVLTSRSLKAPQNLFLVSLAAADILVATLIIPFSLANELMGYWYFGKTWCEMYLALDVLFCTSSIVHLCAISLDRYWSVSQAIEYNSKRTPKRIKCIILIVWTLAALISLPPLIYKGKSKDQN-----AKPECKLNEEPWYILSSSICSFFAPCLIMILVY-------LRIYLIAKRRNRKNSTDKKLKKMAPGLF--SRTNKHSLNSSHTQTQCGIISSQEKTGLALDDLHCGVPVLSSTREERNGHSESFGLQPQGENLKH---TNGCEPAVMDTVATVK--GVMLMPKGAKDSDLSSAKKKSYINREKRFTFVLAVVIGVFVLCWFPFFFTYSLGAICTELCYIPDSVFQFFFWIGYCNSSLNPVIYTIFNQDFRKAFRRILCSHW 410
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Xenopus
Match: ENSXETT00000026158.1 (alpha-2Db adrenergic receptor-like [Source:NCBI gene;Acc:100493940])

HSP 1 Score: 131.724 bits (330), Expect = 8.164e-33
Identity = 96/384 (25.00%), Postives = 176/384 (45.83%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSV--MPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILT 1485
            +GNILVVLA+   + LR   N  ++S+A  D++V   ++  S   E+   W  G  WC  ++  D++ C++SI HL  I++DRYW+VT+ ++Y   RT  ++  +I  IW++S +I+ P        E +          CL+N   +Y L S  ++F+ P + M+++Y                              CR +    R  +   S+  +     +S  +  TC    +T+++   A+ + +    S +      +        S +  + L  S      +  ++I   + ++   RE++    + ++   F++CW PFF    +   C   C +   + +   W+GY N  LNP IYT+F+++FR AF+ ILT
Sbjct:   49 LGNILVVLAIFTSRALRAPQNLFLVSLASADILVGALIIPFSLAREVMGYWHFGSVWCSMYLALDILFCTSSIVHLCAISIDRYWSVTKAVKYNLKRTPKRIKRSIAIIWVVSAIISFPPLLKSKHKEWE----------CLLNDDTWYVLFSCTVSFFVPCLIMILLY------------------------------CRIY----RVAKHRVSSLRNGVSDCNSAAAGGTCE-THHTIQNNHEAEELDLEESTSSVHKFPKKHHHKTKDKPSSAKAKRLSWSSNRGQQHRDQSICISQMRLTQLREKRLTFVLAVVIGGFVICWFPFFFTYSLESVCRKRCGISDALFNFFFWIGYCNSSLNPIIYTVFNRDFRKAFRRILT 387
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Mouse
Match: Htr1a (5-hydroxytryptamine (serotonin) receptor 1A [Source:MGI Symbol;Acc:MGI:96273])

HSP 1 Score: 191.815 bits (486), Expect = 1.870e-54
Identity = 132/401 (32.92%), Postives = 211/401 (52.62%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSI-------NSEIKYQLNVNDVHIARMS----SLSSLRTLKVSVMPYNLTKTIE---EQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWR 1500
            +GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ N+W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  +    I   W+I  +I++P    +   E +          C I+  + YT+ ST  AFY P++ M+++Y +IF+ A+                         F       + E    G  +  +S+   K + +    +    + A+N +V +          E    L V +VH    S     L S  +   S +P  L +  E   E + K+ + RERK + T+GII   FILCW+PFF + LVLPFC + C +  ++ +++ WLGY N LLNP IY  F+++F+ AFK I+   + R
Sbjct:   52 LGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPN-----ECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAAR-------------------------FRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPS-ESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR 421
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Mouse
Match: Htr1b (5-hydroxytryptamine (serotonin) receptor 1B [Source:MGI Symbol;Acc:MGI:96274])

HSP 1 Score: 162.925 bits (411), Expect = 3.162e-44
Identity = 121/385 (31.43%), Postives = 186/385 (48.31%), Query Frame = 1 
Query:  349 NILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRF-HFHRLETQMFQEVVIKGRCLINSGY-FYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQ----YLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            N  V+  V   + L   +NYLI S+A+TDL+V+I VM +S +Y ++ RW LG   CDFW+ +D+  C+ASI HL  IALDRYW +T  +EY   RT  +    I+ +W+ S+ I++P  F    + E +M         C +N+ +  YT+ STV AFY P + ++ +Y +I                             Y     R  +   + TG +     LI  S  S  + + + +   D           + SE    + VN V +                    ++  + E++ K+   RERKA  T+GII   FI+CW+PFF ++LV+P C   C  H  I     WLGYLN L+NP IYT+ +++F+ AF  ++
Sbjct:   63 NAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVEYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEMLD-------CFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRI-----------------------------YVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPD-----------VPSESGSPVYVNQVKV-------------------RVSDALLEKK-KLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLI 380
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Mouse
Match: Htr1b (5-hydroxytryptamine (serotonin) receptor 1B [Source:MGI Symbol;Acc:MGI:96274])

HSP 1 Score: 162.925 bits (411), Expect = 3.162e-44
Identity = 121/385 (31.43%), Postives = 186/385 (48.31%), Query Frame = 1 
Query:  349 NILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRF-HFHRLETQMFQEVVIKGRCLINSGY-FYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQ----YLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            N  V+  V   + L   +NYLI S+A+TDL+V+I VM +S +Y ++ RW LG   CDFW+ +D+  C+ASI HL  IALDRYW +T  +EY   RT  +    I+ +W+ S+ I++P  F    + E +M         C +N+ +  YT+ STV AFY P + ++ +Y +I                             Y     R  +   + TG +     LI  S  S  + + + +   D           + SE    + VN V +                    ++  + E++ K+   RERKA  T+GII   FI+CW+PFF ++LV+P C   C  H  I     WLGYLN L+NP IYT+ +++F+ AF  ++
Sbjct:   63 NAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVEYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEMLD-------CFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRI-----------------------------YVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPD-----------VPSESGSPVYVNQVKV-------------------RVSDALLEKK-KLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLI 380
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Mouse
Match: Htr1f (5-hydroxytryptamine (serotonin) receptor 1F [Source:MGI Symbol;Acc:MGI:99842])

HSP 1 Score: 154.451 bits (389), Expect = 2.395e-41
Identity = 122/385 (31.69%), Postives = 193/385 (50.13%), Query Frame = 1 
Query:  349 NILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINS--SVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYY 1494
            N LV+ A+++ + L + +NYLI S+A+TD +VA+ VM  S VY +   W +G   CD W+  D++ C+ SI HL  IALDRY  +T  +EY   RT       I  +W+IS+ I++P  F  H+  T    E VIK   ++++ Y     ST  AFY P++ ++I+Y+KI                       Y++    +H    +   +    G  +L +   S+K   T  ++E ++ D     +   + I+S +K             S  S L+  K              +R K+   RERKA  T+G+I   F++CW+PFF   LV+  C   C +   +S+ L WLGYLN L+NP IYTIF+++F+ AF+ ++   Y
Sbjct:   41 NSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVLCDIWLSVDIICCTCSILHLSAIALDRYRAITDAVEYARKRTPRHAGIMITIVWVISVFISMPPLFWRHQ-GTSRDDECVIKHDHIVSTIY-----STFGAFYIPLVLILILYYKI-----------------------YRAARTLYHKRQASRMIKEELNGQVFLESGEKSIKLVSTSYMLEKSLSD----PSTDFDRIHSTVK-------------SPRSELKHEK------------SWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCEK-CKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRY 366
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Mouse
Match: Adra2c (adrenergic receptor, alpha 2c [Source:MGI Symbol;Acc:MGI:87936])

HSP 1 Score: 151.754 bits (382), Expect = 1.395e-39
Identity = 115/389 (29.56%), Postives = 184/389 (47.30%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSK--------YKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            VGN+LVV+AVL  + LR   N  ++S+A  D++VA  VM  S   E+   W+ G  WC  ++  DV+ C++SI HL  I+LDRYW+VT+ +EY   RT  ++  TI+++W+IS +I+ P    F+R       +     +C +N   +Y L S + +F+AP + M ++Y +I+++AK + R           D           K+     HC    TE E   +            +      E    D   AD         +     + +     R+S  SS R+++   +           R KV   RE++    + ++   F+LCW PFF    +   C   C +   +     W+GY N  LNP IYT+F+Q+FR +FK+IL
Sbjct:   67 VGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRP-----DGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRRGGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASS-RSVEF-FLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHIL 448
[Close]
BLAST of 5-hydroxytryptamine receptor vs. UniProt/SwissProt
Match: sp|Q25414|5HTR_LYMST (5-hydroxytryptamine receptor OS=Lymnaea stagnalis OX=6523 PE=2 SV=1)

HSP 1 Score: 218.394 bits (555), Expect = 1.079e-62
Identity = 156/410 (38.05%), Postives = 226/410 (55.12%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY---WXXXXXXXX----XXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDM-----KYADNISVNSINSEIKYQLNVNDVHI-----ARMSSLSSL-------RTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWR 1500
            +GN  V+ AV+LE++L N++NYLILS+A+ DL+VA+ VM LS V EIS  WFL    CD WI  DV+ C+ASI HLV IA+DRYW VT I+Y   R+  +++  I+ +W+++L I++P  F +        +     G C+I+    YT+ STV AFY PM+ MMIIY   W + +   R    Q+ + R    E T  +  K+       C+     +  +T ++    +  KS Y CS      ++      + A+ ++ NS +SE   Q+ +          A  +S++ L       + +  +  PY+ T      R K+E+KRERKA  T+ IIT  F++CW+PFF + L+ PF     I  P   S +LWLGY N LLNP IYTIFS EFR AF+ IL G Y R
Sbjct:  111 IGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLVMPLSVVSEISKVWFLHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTSIDYIRRRSARRILLMIMVVWIVALFISIPPLFGWRDPNNDPDK----TGTCIISQDKGYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPD--STTEKKKRRAPFKS-YGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYSRT------REKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDPEGI-PPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRR 506
[Close]
BLAST of 5-hydroxytryptamine receptor vs. UniProt/SwissProt
Match: sp|P08908|5HT1A_HUMAN (5-hydroxytryptamine receptor 1A OS=Homo sapiens OX=9606 GN=HTR1A PE=1 SV=3)

HSP 1 Score: 196.438 bits (498), Expect = 2.618e-55
Identity = 131/391 (33.50%), Postives = 216/391 (55.24%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLIN--SSVKSKYTCSLMEN-TVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRR 1503
            +GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ N+W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  +    I   W+I  +I++P    +   E +   +      C I+  + YT+ ST  AFY P++ M+++Y +IF+ A+ +IR+  +   +   D++        H      + + S  G+    N    V+SK   +L  N  VR       + V  +     +++  +  H+   S          S    N  +   E + K+ + RERK + T+GII   FILCW+PFF + LVLPFC + C +  ++ +++ WLGY N LLNP IY  F+++F+ AFK I+   + R+
Sbjct:   52 LGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDA-----CTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTR--------HGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEV-----HRVGNSKEHLPLPSEAGPTPCAPASFERKN--ERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 422
[Close]
BLAST of 5-hydroxytryptamine receptor vs. UniProt/SwissProt
Match: sp|Q9N297|5HT1A_GORGO (5-hydroxytryptamine receptor 1A OS=Gorilla gorilla gorilla OX=9595 GN=HTR1A PE=3 SV=1)

HSP 1 Score: 196.052 bits (497), Expect = 3.424e-55
Identity = 131/391 (33.50%), Postives = 216/391 (55.24%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLIN--SSVKSKYTCSLMEN-TVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRR 1503
            +GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ N+W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  +    I   W+I  +I++P    +   E +   +      C I+  + YT+ ST  AFY P++ M+++Y +IF+ A+ +IR+  +   +   D++        H      + + S  G+    N    V+SK   +L  N  VR       + V  +     +++  +  H+   S          S    N  +   E + K+ + RERK + T+GII   FILCW+PFF + LVLPFC + C +  ++ +++ WLGY N LLNP IY  F+++F+ AFK I+   + R+
Sbjct:   52 LGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDA-----CTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTR--------HGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEV-----HRVGNSKEHLPLPSEAGPTPCAPASFERKN--ERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 422
[Close]
BLAST of 5-hydroxytryptamine receptor vs. UniProt/SwissProt
Match: sp|Q9N298|5HT1A_PANTR (5-hydroxytryptamine receptor 1A OS=Pan troglodytes OX=9598 GN=HTR1A PE=3 SV=1)

HSP 1 Score: 196.052 bits (497), Expect = 3.495e-55
Identity = 131/391 (33.50%), Postives = 216/391 (55.24%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLIN--SSVKSKYTCSLMEN-TVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRR 1503
            +GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ N+W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  +    I   W+I  +I++P    +   E +   +      C I+  + YT+ ST  AFY P++ M+++Y +IF+ A+ +IR+  +   +   D++        H      + + S  G+    N    V+SK   +L  N  VR       + V  +     +++  +  H+   S          S    N  +   E + K+ + RERK + T+GII   FILCW+PFF + LVLPFC + C +  ++ +++ WLGY N LLNP IY  F+++F+ AFK I+   + R+
Sbjct:   52 LGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDA-----CTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTR--------HGASPAQQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEV-----HRVGNSKEHLPLPSEAGPTPCAPASFERKN--ERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 422
[Close]
BLAST of 5-hydroxytryptamine receptor vs. UniProt/SwissProt
Match: sp|O42385|5H1AA_TAKRU (5-hydroxytryptamine receptor 1A-alpha OS=Takifugu rubripes OX=31033 GN=htr1aa PE=3 SV=1)

HSP 1 Score: 195.282 bits (495), Expect = 6.578e-55
Identity = 125/384 (32.55%), Postives = 197/384 (51.30%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKY----TCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ N+W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  +    I   W+I   I++P    +   E +   +      C+I+    YT+ ST  AFY P+I M+++Y           R  +   + +    K     +    C   + + F    +   +++  K  Y    +       VR  +  +++ +  +NS  K  L               L     S    N+ +     R K+ + RERK + T+GII   FI CW+PFF + LVLPFC   C +   + +V+ WLGY N LLNP IY  F+++F+ AFK IL
Sbjct:   62 GNSCVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQDICDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAVLISVTWLIGFSISIPPMLGWRSAEDRANPDA-----CIISQDPGYTIYSTFGAFYIPLILMLVLY----------GRIFKAARFRIRKTVKKTEKAKASDMCLTLSPAVFHKRANGDAVSAEWKRGYKFKPSSPCANGAVRHGEEMESLEIIEVNSNSKTHL--------------PLPNTPQSSSHENINEKTTGTRRKIALARERKTVKTLGIIMGTFIFCWLPFFIVALVLPFCAENCYMPEWLGAVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIL 416
[Close]
BLAST of 5-hydroxytryptamine receptor vs. TrEMBL
Match: A0A193KUL5 (GCR090 OS=Schmidtea mediterranea OX=79327 GN=gcr090 PE=2 SV=1)

HSP 1 Score: 781.171 bits (2016), Expect = 0.000e+0
Identity = 432/433 (99.77%), Postives = 433/433 (100.00%), Query Frame = 1 
Query:  217 MVHNHTVTALNSSAFPGFQLKHGXXXXXXXXXXXXXXXXXXXVGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRRCIDR 1515
            MVHNHTVTALNSSAFPGFQLKHGIIHFILTLLILETFIMLTIVGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWKIFQIAKRQIRRKRRFNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTV+DMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVLLWLGYLNCLLNPFIYTIFSQEFRCAFKNILTGYYWRRCIDR
Sbjct:    1 MVHNHTVTALNSSAFPGFQLKHGIIHFILTLLILETFIMLTIVGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWKIFQIAKRQIRRKRRFNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVKDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVLLWLGYLNCLLNPFIYTIFSQEFRCAFKNILTGYYWRRCIDR 433
[Close]
BLAST of 5-hydroxytryptamine receptor vs. TrEMBL
Match: A0A210PSA3 (5-hydroxytryptamine receptor OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19253 PE=3 SV=1)

HSP 1 Score: 228.794 bits (582), Expect = 1.108e-64
Identity = 154/394 (39.09%), Postives = 213/394 (54.06%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKY--ADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTK---TIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCG--AYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRR 1503
            +GN+ V+ A++LEKNL N++NYLILS+A+ DL+VA  VM +S V EIS  WFL    CD WI  DV+ C+ASI HLV I++DRYW VT I+Y  NR+  Q++  I   WM+ + I++P  F +     +     V+ G CLI+    YT+ ST  AFY P + MMIIY KI                   F    + I R         ++E     D      S KSK    L+ N+ +   +  ADN  +    +      N ND +       +     K +++P  + K     ++Q+ K+E+KRERKA  T+GIIT  FI+CW+PFF + L  P  G  A  I   +IS V LWLGY N LLNP +YTIFS +FR AF+ IL G Y ++
Sbjct:   91 IGNVFVIAAIILEKNLHNVANYLILSLAVADLMVATLVMPISVVNEISTVWFLRPEICDMWISFDVLCCTASILHLVAISVDRYWAVTNIDYVRNRSAKQILSMIALSWMVGMCISIPPLFGWK----EPANSPVLTGTCLISQDIGYTVFSTFGAFYVPTLIMMIIYAKI-------------------FQVARRRIRRKNFHKKSLKKAEAKIKSDH-----SSKSK----LLFNSPKSNGHNSADNTEITVNETSCNGNENYNDKNENSKVDTNGFDDAKTAMIPKAVNKEQDKAKKQKEKLEMKRERKAARTLGIITGAFIICWLPFFIIALTAPLVGKAAEEIPEELISFV-LWLGYANSLLNPILYTIFSPDFRNAFQKILFGKYSKK 451
[Close]
BLAST of 5-hydroxytryptamine receptor vs. TrEMBL
Match: Q2PGF5 (5-HT receptor OS=Mizuhopecten yessoensis OX=6573 GN=5-HTpy PE=2 SV=1)

HSP 1 Score: 228.024 bits (580), Expect = 2.098e-64
Identity = 154/394 (39.09%), Postives = 212/394 (53.81%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKY--ADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTK---TIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCG--AYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRR 1503
            +GN+ V+ A +LEKNL N++NYLILS+A+ DL+VA  VM +S V EIS  WFL    CD WI  DV+ C+ASI HLV I++DRYW VT I+Y  NR+  Q++  I   WM+ + I++P  F +     +     V+ G CLI+    YT+ ST  AFY P + MMIIY KI                   F    + I R         ++E     D      S KSK    L+ N+ +   +  ADN  +    +      N ND +       +     K +++P  + K     ++Q+ K+E+KRERKA  T+GIIT  FI+CW+PFF + L  P  G  A  I   +IS V LWLGY N LLNP +YTIFS +FR AF+ IL G Y ++
Sbjct:   91 IGNVFVIAATILEKNLHNVANYLILSLAVADLMVATLVMPISVVNEISTVWFLRPEICDMWISFDVLCCTASILHLVAISVDRYWAVTNIDYVRNRSAKQILSMIALSWMVGMCISIPPLFGWK----EPANSPVLTGTCLISQDIGYTVFSTFGAFYVPTLIMMIIYAKI-------------------FQVARRRIRRKNFHKKSLKKAEAKIKSDH-----SSKSK----LLFNSPKSNGHNSADNTEITVNETSCNGNENYNDKNENSKVDTNGFDDAKTAMIPKAVNKEQDKAKKQKEKLEMKRERKAARTLGIITGAFIICWLPFFIIALTAPLVGKAAEEIPEELISFV-LWLGYANSLLNPILYTIFSPDFRNAFQKILFGKYSKK 451
[Close]
BLAST of 5-hydroxytryptamine receptor vs. TrEMBL
Match: A0A2C9JN07 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106060614 PE=3 SV=1)

HSP 1 Score: 227.254 bits (578), Expect = 7.979e-64
Identity = 148/406 (36.45%), Postives = 222/406 (54.68%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHF-HRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFS------TTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVND--------VHI-----ARMSSLSSLRTLKVSVMPYNLTKTIEE-------QRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNI 1479
            +GNI V+ A+L+E++L  +SNYLILS+A TDL+VA+ VM +S + E+S +WFLG A CD W+  DV+ C+ASI HLV IA DRYW V+ I+Y  +R+  Q++F +  +WM+S+ I++P  F + H  +   F      G+CLI+  Y YT+ ST+ AFY P++ M+II                  N+++   ++Y+   + F    RTT+           T  +    +S  S  +   +     D+   D   + S   E +    V+D        VH      A M  LS  R+  +S    N++K +         +R K+E++RERKA   +GIIT  F++CW+PFF L ++ P CG  C +   + S+ LWLGY N L+NP IYTIF+  FRCAF  I
Sbjct:   84 LGNIFVITAILVERSLHGVSNYLILSLATTDLLVAVLVMPVSLINEVSVKWFLGAALCDMWVSMDVLCCTASILHLVAIAFDRYWAVSNIDYIRSRSAKQILFMVAVVWMVSICISIPPLFGWRHNTDGPDFS-----GQCLISQDYGYTIFSTLGAFYCPLVLMLII------------------NFKIYRAARYRIRKKRF--VGRTTKYHVPLPIVTMETSQRLTARNSSGSDVSQDGVSTNANDVTRLD---MESPLDEPETGQPVSDYEANLTRVVHTTLTVPANMVHLSVTRSNVLS--NNNVSKRVRRGGDKERYRREKMEMRRERKAARVLGIITGAFVVCWLPFFILAVLNPLCGTMCSIPSYVVSLSLWLGYFNSLINPIIYTIFNPSFRCAFNKI 459
[Close]
BLAST of 5-hydroxytryptamine receptor vs. TrEMBL
Match: R7UP08 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_121888 PE=3 SV=1)

HSP 1 Score: 224.172 bits (570), Expect = 1.744e-63
Identity = 151/394 (38.32%), Postives = 216/394 (54.82%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVK----SKYTC---SLMENTVRDMKYADNISVNSINSEIKYQ---LNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYY 1494
            +GN+ V+ AV+LE+NL N++NYLI S+A+ DL+VA  VM L+AV E+S +WFLG   CD ++  DV+ C++SI HLV I+LDRYW VTR++Y HNR+ S+++  I   W IS  I++P  F + + E  + +     G CLI+    YT+ ST+ AFY P+  M+IIY     I   Q  R R         +  K +         TT++   T+    L  S       S  +C   S+  +  R+ K        + N E +     +++  V+  ++ S  S RT                 + K+E KRERKA  T+ IIT  FI+CW+PFF + LV PFCG  C    I+ S++ WLGY N LLNP IYTIF+ +FR AF+ IL G Y
Sbjct:   25 IGNVFVIAAVILERNLHNVANYLIASLAVADLMVAALVMPLAAVNEVSKQWFLGPEICDMFVSFDVLCCTSSILHLVCISLDRYWAVTRVDYIHNRSASRILVMIALSWAISASISIPPLFGW-KDEKHLDKT----GECLISQDLGYTVFSTLGAFYLPLSLMIIIY-----IKIFQAARSRIRKKHFKKSAPKKQLLLRRSPPGSTTDTTALTSSATPLAPSPGHNTECSNGSCVSESVANDANRNNKLLTVSPPPTPNKEPEQNSSWIDLTKVNKTQLQSPKSKRT-----------------KEKIEQKRERKAARTLAIITGSFIVCWLPFFIIALVRPFCGDLCHYPDILMSIIGWLGYFNSLLNPIIYTIFNPDFRSAFRKILFGKY 391
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Cavefish
Match: ENSAMXT00000006138.2 (pep primary_assembly:Astyanax_mexicanus-2.0:6:27993956:27999385:-1 gene:ENSAMXG00000005992.2 transcript:ENSAMXT00000006138.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 182.956 bits (463), Expect = 2.016e-51
Identity = 124/392 (31.63%), Postives = 200/392 (51.02%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVM--PYNLTKTIEE--QRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRR 1503
            VGN  V+ A+ LE++L+ ++NYLI S+A+TDL+V++ V+ ++A+Y++  RW LG   CD +I  DV+ C++SI HL  IALDRYW +T  + Y   RT+ +    I   W++   I++P    +   E +          C I+    YT+ ST  AFY P+  M+++Y            R  R        S  K+  +               TG+         +   C+ +  T           VN ++S    +++  D   A     +SL + +V+ +  P  ++    E  Q  +  + RER+ + T+GII   FILCW+PFF + LVLPFCG+ C + P + +V+ WLGY N LLNP IY  F+++F+ AF+ +L   + R+
Sbjct:   49 VGNACVIAAIALERSLQTINNYLIGSLAVTDLLVSVLVLPMAALYQVLQRWTLGQVACDLFIALDVLCCTSSILHLCAIALDRYWAITDPVAYMTRRTLCRAATLISLTWLVGFSISIPPMLGWRTPEDRANPL-----ECTISQDPGYTIFSTFGAFYIPLALMLVLY-----------GRIFRAARFRIRRSAKKNTDKMKMKEKEKDRKGTGLTGN--------GAPSPCTSVTGTP---------DVNRVSSPDDPRIDTPDGTRASTPDSTSLGSPEVTRVGTPEGISLEGTELLQDSRGALARERRTVKTLGIIMGTFILCWLPFFIVALVLPFCGSSCPMPPWLGAVINWLGYANSLLNPVIYAYFNRDFQNAFRKMLRCRFSRQ 407
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Cavefish
Match: htr1ab (5-hydroxytryptamine (serotonin) receptor 1A b [Source:ZFIN;Acc:ZDB-GENE-090409-2])

HSP 1 Score: 182.185 bits (461), Expect = 4.716e-51
Identity = 126/388 (32.47%), Postives = 206/388 (53.09%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVT-RIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEF-STTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPY-NLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWR 1500
            GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++ +Y++ +RW LG   CD +I  D++ C++SI HL  IALDRYW +T  I+Y   RT+ +    I   W++   I++P             +++     C+I+   +YT+ ST  AFY P+I M+++Y +IF+ A+ +IR+  R + +V               C   + + F  + G+     SSV+ K          +     +++ +            V +V      S   L      V  + N  +   E + K+ + RERK + T+GII   FILCW+PFF   LV+PFC + C +   +  V+ WLGY N LLNP IY  F+++F+ AFK I+  ++ R
Sbjct:   54 GNSCVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMACLYQVLDRWTLGQVTCDIFISLDILCCTSSILHLCAIALDRYWAITDPIDYMKKRTLKRAAVLIGVTWLVGFSISIPPMLIMKSQPKSKAEDIANPEACMISHDPWYTIYSTFCAFYIPLILMLVLYGRIFKAARFRIRKTVRKSEKVK--------------CLTVSPALFKKSNGELKSWRSSVEPKPIADCSNGAAKRHDDGESLEI------------VEEVQPGGAKSSLPLPNAPGQVPLFENRHEKNTEAKRKLALARERKTVKTLGIIMGTFILCWLPFFIKALVMPFCPS-CQMPVWLMDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCHFCR 414
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Cavefish
Match: HTR1F (5-hydroxytryptamine receptor 1F-like [Source:NCBI gene;Acc:103023679])

HSP 1 Score: 146.747 bits (369), Expect = 1.386e-38
Identity = 113/382 (29.58%), Postives = 186/382 (48.69%), Query Frame = 1 
Query:  349 NILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRF--HFHRLETQMFQEVVIKGRCLINSGYF-YTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            N LV+ A+L+ + L   +NYLI S+A+TDL+VA+ VM +S +Y     W LG   C  W+  DV  C+ SI HL  IA DRY  +T  + Y   RT  +   TI+ +W++S+++++P      F  +  Q+   VV+   CLI   +  +T+ ST  AFY P+  ++++Y+KI                                  +R  ++  +  G   L+  +V      S+M ++ RD   + +       S      + + V IA  +                  +TI  +R      RER+A +T+G+I   F++CW+PFF   +++  C + C     ++  L WLGYLN L+NP IYTIF+++F+ AF+ +L
Sbjct:   41 NSLVITAILVTRKLHQPANYLICSLAVTDLLVAVLVMPVSIIYIAEEEWVLGPIVCHLWLGVDVTCCTCSILHLAAIAHDRYRAITDAVAYSQKRTSRRAAATIIVLWVLSILVSLPPLMWRRFPNIREQIGDRVVMD--CLIEHDHVAFTVYSTFGAFYIPLTLILVLYYKI----------------------------------YRAAQTLRNRRGSSRLVQQTVS-----SVMISSERDAPLSPDTLSPIEKSFSDPSTDCDRVRIAPTTG-----------------RTIRSRR--APGARERRAALTLGLILGAFVICWLPFFLKEVIVNSCPS-CSTSAFLADFLTWLGYLNSLINPLIYTIFNEDFKKAFQKLL 361
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Cavefish
Match: adra2b (adrenoceptor alpha 2B [Source:NCBI gene;Acc:266751])

HSP 1 Score: 137.502 bits (345), Expect = 6.758e-35
Identity = 107/388 (27.58%), Postives = 190/388 (48.97%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY---WXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLME----NTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            VGNILV++AVL  ++LR   N  ++S+A  D++VA  ++  S   E+   W+    WC+ ++  DV+ C++SI HL  I+LDRY +++R + Y   RT  ++   IL +W+IS +I+ P     ++   +   +     +C +N+  +Y L ST+ +F+AP + M+++Y   ++I +   R    + R     +   +  +     +     +     T  D+   N++ +S  + S  E     T   M  +   S   I+S    Q   + +  A+ + L+S ++ +          T    R K  V RE++    + ++   F++CW PFF    +   C   C +   +     W+GY N  LNP IYTIF+++FR AFK IL
Sbjct:   36 VGNILVIIAVLTSRSLRGPQNLFLVSLAAADILVATLIIPFSLANELMGFWYFKSVWCEIYLALDVLFCTSSIVHLCAISLDRYLSISRAVTYGAQRTPRRIKCAILIVWLISAVISFPPLLSMNK---KKGTDEAGCPQCELNNERWYILYSTIGSFFAPCLIMILVYMRIYQIAKQRTRCPPGEPRKEIPASAKQQPATTPTTNNLLPPPSLGTALTPPDKKPDNNNGESSTSDSDTEQGGVGTEMPMTPSGEPSAG-IHSPATIQKYRDMIATAKGTRLASRKSKQ--------DGTPNSARRKAMVNREKRFTFVLAVVIGVFVVCWFPFFFSYSLQAVCPRTCNLPEPLFKFFFWIGYCNSCLNPVIYTIFNKDFRRAFKKIL 411
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Cavefish
Match: adra2a (adrenoceptor alpha 2A [Source:NCBI gene;Acc:266750])

HSP 1 Score: 135.961 bits (341), Expect = 1.242e-34
Identity = 111/389 (28.53%), Postives = 179/389 (46.02%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKG--RCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRR 1503
            GN+L V+AV   + L+   N  ++S+A  D++VA  VM  S   E+   W+ G  WC  ++  DV+ C+ASI HL  I+LDRYW++TR +EY   RT  ++   IL +W+I+ +I+ P         T M ++  I     C IN   +Y + S + +F+ P I M+++Y +I+QIAK + R       +   + K        H CH     + +   D+                 +   D+   D    +S + ++              + LS ++         N  +  +  R K    RE++    + ++   F++CW PFF    +   C + C V+  +     W GY N  LNP IYTIF+ +FR AFK IL     RR
Sbjct:   29 GNLLAVIAVFTSRALKAPQNLFLVSLASADILVATLVMPFSLANELMGYWYFGPVWCKIYLALDVLFCTASIAHLCAISLDRYWSITRAVEYNLKRTPRRIKCVILVVWVIAAVISFPPL-------TIMKEDEPINDPPSCQINKDKWYIISSCIGSFFLPCIIMVLVYIRIYQIAKSRTRTPPGDRRKRDDEKKENG-----H-CHERLNGDAANGNDK-----------------DDKGDVNAVDMEESSSSDHKVTNPCASKKKRAKGKTKLSQIKPGDDINKRENANRGTKSSRWKGRQNREKRFTFVLAVVIGVFMICWFPFFFTYTLRALCES-CCVNETLFKFFFWFGYCNSSLNPIIYTIFNNDFRRAFKKILCRGDSRR 386
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Sea Lamprey
Match: HTR1F (5-hydroxytryptamine receptor 1F [Source:HGNC Symbol;Acc:HGNC:5292])

HSP 1 Score: 174.096 bits (440), Expect = 1.120e-48
Identity = 122/399 (30.58%), Postives = 198/399 (49.62%), Query Frame = 1 
Query:  349 NILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGY-FYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINS-SVKSKYTCSLMENTVRDMKYADNI---------SVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYN----LTKTIEEQR----HKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILT 1485
            N LV+ A+   + LR  +NYLI S+A+ DL+VA  VM ++A Y ++  W LG A CD W+  DV  C+ASI HL  IALDR+W +T   EY H RT  +    I + W+++  I+VP  F   R           K RC+I   +  YT+ ST  AFY P+  ++ +Y                              CR F    R  E   S   ++  +++ S  S    S  ++  +  + A  +         S  S + +   Q   +  H   +S+++  R  K S+ P      ++  ++++R     ++   RER+A  T+G+I   F++CW+PFF   LV+  C + C V P ++ +L WLGY+N L+NP IYT+F+++F+ AF+ +++
Sbjct:   65 NALVIAAISATRKLRQPANYLIGSLAVADLLVAALVMPVAAAYVVTGEWALGGALCDLWLSLDVTCCTASILHLCAIALDRFWAITDAAEYAHKRTPGRAALMIAASWLLAACISVPPLFWRRRDPA--------KPRCIIEHDHVLYTIYSTFGAFYVPLALLLALY------------------------------CRIFRAAKRLYEKRESKQREKLSVSAESAVSLEQPSQSQHQQQQQQPAGKLFRLPQPFCMSETSSSDQTLAQAERSGQHQQSVSAVA--RRSKRSLRPPRSVRFMSARLDQRRPCLQERISGSRERRAAKTLGLILGAFVVCWLPFFIKELVVNLCKS-CAVSPEVADLLTWLGYMNSLINPLIYTMFNEDFKSAFRKLVS 422
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009127.1 (pep scaffold:Pmarinus_7.0:GL478629:43196:44446:-1 gene:ENSPMAG00000008256.1 transcript:ENSPMAT00000009127.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 135.576 bits (340), Expect = 3.510e-35
Identity = 66/168 (39.29%), Postives = 105/168 (62.50%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY 846
            GN  V+ A+ LE+ L+N++NYLI S+A+TDL+V+I V+ ++A+Y++ +RW LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  + +  I   W++   I++P    +   E +          C I+  + YT+ ST  AFY P+I M+++Y
Sbjct:   53 GNSCVIAAIALERTLQNVANYLIGSLAVTDLLVSILVLPMAALYQVLDRWTLGQVVCDIFIALDVLCCTSSILHLCVIALDRYWAITNPIDYVNKRTPRRAVIMISLTWLVGFSISIPPMLGWRTPEDRADPNA-----CKISQDHGYTIYSTFGAFYIPLILMLVLY 215
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001357.1 (pep scaffold:Pmarinus_7.0:GL478256:17157:19157:1 gene:ENSPMAG00000001226.1 transcript:ENSPMAT00000001357.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 121.324 bits (303), Expect = 2.530e-30
Identity = 95/366 (25.96%), Postives = 173/366 (47.27%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARM---SSLSSLRTLKVSVMPY----------------NLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPII 1380
             GN  V+ A+ LE++L+ ++NYLI S+A+TDL+V++ V+ ++A+Y++  RW LG A CD +I  DV+ C++SI HL  IALDRYW +T  ++Y + RT  +    I   W++   I++P    + + E +   +      C I+    YT+ ST  AFY P++ M+++Y           +      + +  +  +KS           + ++  +         +       S      ++ K + N+S         Y  N+  +   ++   S++S+L+T+ + +MP                 NL +T    R+++   R  K+   + I +   I   +     TLV+PFCG  C + PI+
Sbjct:   18 AGNAFVLAAIYLERSLQTVANYLIGSLAVTDLLVSVLVLPVAALYQVLGRWTLGQAVCDAFIALDVLCCTSSILHLCAIALDRYWAITDPVDYVNKRTPRRAALMIAITWVVGFSISIPPMLGWRQAEDRADPDA-----CNISQHLGYTIYSTFGAFYIPLVLMLVLY----------GKIFSAARFRIRKNVAFKS----------ASHTDNGSADGPMDREEADGDGGGGSGGGRVGQERKRSQNMS--------SYNCNLQTIGSNQLIISSNISNLQTIIMMMMPISSIVISSSNLRKLNSRNLQRTRGSNRNRISSNRCMKS--NLQISSSNSINNDLQTNLTTLVVPFCGPPCELPPIL 348
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Sea Lamprey
Match: adra2c (adrenoceptor alpha 2C [Source:NCBI gene;Acc:266752])

HSP 1 Score: 117.087 bits (292), Expect = 2.116e-28
Identity = 58/168 (34.52%), Postives = 102/168 (60.71%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY 846
            GN LV++AVL   +L+   N  ++S+A  D++VA  V+  S   E+   W+ G  WC+ ++  DV+ C++SI HL  I+LDRYW+V++ +EY   RT  ++   I+ +W I++ I++P     ++   Q  QE V +  C +N+  +Y L S + +F+AP + M+++Y
Sbjct:   68 GNCLVIIAVLTRPSLKAPQNLFLVSLATADILVATLVIPFSLFNELMGYWYFGRVWCEIYLALDVLFCTSSIVHLCAISLDRYWSVSQAVEYNIKRTPRRIKRIIVIVWFIAIAISLPPLISMNQKNRQQ-QEEVGRPNCELNTNTWYILGSCIGSFFAPCLIMVLVY 234

HSP 2 Score: 49.2914 bits (116), Expect = 1.725e-6
Identity = 31/87 (35.63%), Postives = 46/87 (52.87%), Query Frame = 1 
Query: 1225 EQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAY-CIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
             +R K+   RER+    + ++   F++CW PFF    +   C    C +   +     W GY N  LNP IYT+F+++FR AFK IL
Sbjct:  368 RERRKIAQARERRFTFVLSVMIGVFVICWFPFFFTYSLSALCSPESCAIPETLFKFFFWFGYCNSCLNPVIYTVFNRDFRRAFKKIL 454
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Sea Lamprey
Match: chrm5b (cholinergic receptor, muscarinic 5b [Source:ZFIN;Acc:ZDB-GENE-041001-169])

HSP 1 Score: 116.316 bits (290), Expect = 7.222e-28
Identity = 59/172 (34.30%), Postives = 101/172 (58.72%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLIN--SGYFYTLLSTVIAFYAPMIFMMIIYW 849
            VGN LV+L+  + + L+ +SNY +LS+A  DL+V +F MNL   Y ++ RW +G   CD W+  D ++ +AS+ +L+ I+ DRY+++TR ++YK  RT  +    I   W +SL++  P+   +  +   + +  V + +C I   S    T  + + AFY P+  MM++YW
Sbjct:   46 VGNTLVMLSFRVSRQLKTVSNYFLLSLAAADLIVGLFSMNLYTAYILTGRWAMGAVMCDLWLTLDYVASNASVMNLLAISFDRYFSITRPLKYKAKRTKRRASIMIGLAWAVSLVLWAPAILFWQHM---VGKRTVPQDQCYIQFLSEPIITFGTAIAAFYLPITIMMVLYW 214
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Nematostella
Match: EDO35450 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLG6])

HSP 1 Score: 84.3445 bits (207), Expect = 5.138e-18
Identity = 57/169 (33.73%), Postives = 96/169 (56.80%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEI-SNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVT-RIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY 846
            GN+LV  A+L  + LR ++NY I+S+A++DL+VA   M     + + S  W LGI+ C+FWIF D++  SASI +L  I++DR+  ++  + Y    T  + +  I  +W  SL+I+  S F        + Q++     C +   Y+YT + TV  F+ P++ ++I Y
Sbjct:   26 GNLLVCGAILSYRRLRTVTNYFIISLAVSDLLVAGLSMPFRIHHTLHSMCWDLGISVCEFWIFVDLVCSSASICNLSMISVDRFLALSYPLTYPSIMTKRRGLLAIAMVWGYSLLISALS-FTLPWSPDGLMQDI---PACSLKDKYYYTFVITV-GFFLPLVVLVIAY 189

HSP 2 Score: 47.3654 bits (111), Expect = 8.687e-6
Identity = 39/121 (32.23%), Postives = 58/121 (47.93%), Query Frame = 1 
Query: 1180 LKVSVMPYNLT-KTIEEQRHKVE----------VKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVH---PIISSVXXXXX------XXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            L V V+ Y+L  K    Q  K++          + RE KA  T+ I+   FI+CW+PFF +   + FC      H   P+ + + +          LN  +NP IY+ F+  FR AFK+IL
Sbjct:  182 LVVLVIAYSLVFKVALHQARKLQLLSSGGFDPSIIRELKATKTLAIVVGSFIVCWLPFFVIMFTVQFCPECFQDHRSLPVKAQLAIGTVFVYVLPLLNSAVNPIIYSSFNANFRRAFKDIL 302
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Nematostella
Match: EDO47359 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMJ9])

HSP 1 Score: 85.1149 bits (209), Expect = 1.026e-17
Identity = 97/407 (23.83%), Postives = 172/407 (42.26%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNR-W--FLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDV-HIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCI----VHPIISSVXX-----XXXXXXXXXNPFIYTIFSQEFRCAFKNI---LTGYYWRRCID 1512
            +GN+LV  +V   + LR+ +NYL++S+A++DL+V    +       ++   W   LG   C FWI+ D++   AS+ +L  I+ DR   + + + Y+   T  + +  IL +W+ +   A  S   +    T     +    +C I +  + TL++ + AF+ P++ ++I Y  + Q+A R   + ++   ++  +                  +    +G+  L +  V       +   T R   +  +I  N  N   K++   +   HI  M  + + +TL V                             VG+    FILCW PFF + +   +C   C     + P +  VLL      L   N   NP IY+ F+QEFR AF  I   + G  +R+  D
Sbjct:   39 MGNLLVCYSVFYYRRLRSPTNYLVVSLAVSDLLVGTLSLPFRLAQLLNEENWPSHLGREGCQFWIWVDMLCSGASMVNLAGISFDRLLAIKQPLRYREKMTSKRALILILVVWIYAASCAFLSFVEWEGEST-----IAAYPQCGIRARVYITLMA-LAAFFCPLLIVIICYGMVLQVAIRHALQVQKEKEQIALN-----------VSPEPNSNNHEESGETSLASPPV-------IRLKTSRSSSHRKDI--NFANGHAKHRNPASSTFHI--MKQIKATKTLAV----------------------------VVGV----FILCWFPFFVIFVTFQYCDTECFGEERIPPAVKRVLLIIFVYVLPVSNSAANPIIYSCFNQEFRVAFLKIFYKMVGKRYRQKYD 385
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Nematostella
Match: EDO43835 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXF3])

HSP 1 Score: 83.9593 bits (206), Expect = 1.622e-17
Identity = 87/346 (25.14%), Postives = 150/346 (43.35%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNL-SNYLILSMAITDLVVAIFVMNLSAVYEI-SNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVT----RIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYC 1362
            VGN+LV  AV++  NLR++ S+Y I+S+AI+DL  A F M     Y I S  W  G  +C  W    +++   SI +L+ +++DRY T+     R       T  + +  IL +W  SL  A+          + ++Q     G C+ N    Y+++ + + F  PM+ M  +Y+KIF+IA                 +KY+   R     H+  +           +N   KS      +   V +++ +  +     ++    + N N    A + +       +   M +   + +  +R K  VK   KA  T+ +I   F+LCW PF   ++V+  C   C
Sbjct:   12 VGNLLVCAAVVVNANLRHVVSSYFIVSLAISDLATACFSMPFDMEYLITSGLWPRGEDFCIVWTTVYMIAIPTSILNLLVLSIDRYKTLKDPWDRFRESPFITKRRAVIAILVLWGYSLAFALVPITGVKHYPSSLYQ-----GTCIFNMAPIYSVVGSFVNFVLPMLIMCCMYYKIFRIA----------------HTKYRMPSRPKRDMHQVMQLP--------AMNEESKSPPDAEKVPPAVNNIRNSTKLRSRKKSA----KKNNNSPEKAGLENAG----FEEKPMNFGSMEDLTIRRKKYFVKNA-KAARTISVIVGAFLLCWGPFVLFSIVMNICWMPC 319
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Nematostella
Match: EDO32939 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STN0])

HSP 1 Score: 82.8037 bits (203), Expect = 2.581e-17
Identity = 51/170 (30.00%), Postives = 91/170 (53.53%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISN-RWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYW-TVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY 846
            +GN  V L V L  +L   +NY++ S+A++DL+VA+F +       + N  W LG + C FWI+ D+  C ASI +L  I+LDR+  T   + Y+     +  I  ++++W+ S ++A  S  ++   E  + + +     C     YFYT  +  + F+ P+I +++ Y
Sbjct:   36 LGNATVCLTVFLTSSLHAFTNYIVASLAVSDLMVALFSLPFRIHQTVHNTHWCLGASACAFWIWADMFCCCASIMNLALISLDRFLATKYPLNYQELINRAGKIAMVVTVWLYSFVVASLSLRNWTSPEGPLVKTI---NGCFKPDPYFYT-FAAALGFFLPLIVIILAY 201
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Nematostella
Match: EDO36610 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI87])

HSP 1 Score: 80.1073 bits (196), Expect = 1.358e-16
Identity = 51/174 (29.31%), Postives = 103/174 (59.20%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEI-----SNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQL--IFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY 846
            GN +VVLAV+L   +R ++NY ++S+A++DL+VA     LS  + I     +  W LG+  C  WI  D++ C ASI++L  I++DR+  +  + ++++  M+ +  +  I ++W++S+ + + S  ++  L +  F    I+ +C      +YT++S V+ F+ P+  ++++Y
Sbjct:   15 GNFMVVLAVVLFHRMRTITNYFVVSLAVSDLLVA----TLSLPFRIHQTTHNTAWCLGLEACVAWIVVDIICCGASIWNLAMISVDRFIAIV-MPFRYHALMTPMTGVCLIGAVWILSMGMGMLSLINWTELGSPHFH---IEVQCRKFDPVYYTVVS-VVGFFLPLFIVLLMY 179
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Medaka
Match: ENSORLT00000005282.2 (pep primary_assembly:ASM223467v1:9:8571029:8576106:1 gene:ENSORLG00000004220.2 transcript:ENSORLT00000005282.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 190.66 bits (483), Expect = 3.509e-54
Identity = 128/387 (33.07%), Postives = 210/387 (54.26%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPY-NLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWR 1500
            GN  VV A+ LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ N+W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y + RT  + +  I + W+I   I++P    +   E +   +      C+I+    YT+ ST  AFY P+I M+++Y +IF+ A+ +IR+  +         K  ++   F   H+ +  +    G +        SK +   +   V      +++ +  + S  K  L + +             T + S   Y N+ +     + K+ + RERK + T+GII   FI CW+PFF + LVLPFC   C +   + +V+ WLGY N LLNP IY  F+++F+ AFK I+   + R
Sbjct:   59 GNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQEICDLFISLDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPMRAVLLICATWLIGFSISIPPMLGWRSAEDRANPDA-----CMISQDPGYTIYSTFGAFYIPLILMLVLYGRIFRAARFRIRKTVKKIETAKVSDKCLAVSPAFF--HKKSNGQSGGRGWKRCDG----SKPSSPCVNGAVMHGDEGESLEIIEVISNSKTHLPLPN-------------TPQSSSHGYENMNERNSGAKRKLALSRERKTVKTLGIIMGTFIFCWLPFFIVALVLPFCPESCFMPDWLGAVINWLGYSNSLLNPIIYAYFNKDFQNAFKKIIKCKFHR 421
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Medaka
Match: htr1ab (5-hydroxytryptamine (serotonin) receptor 1A b [Source:ZFIN;Acc:ZDB-GENE-090409-2])

HSP 1 Score: 189.504 bits (480), Expect = 7.434e-54
Identity = 123/389 (31.62%), Postives = 195/389 (50.13%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKY-----QLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYY 1494
            GN  VV A++LE++L+N++NYLI S+A+TDL+V++ V+ ++A+Y++ N W LG   CD +I  DV+ C++SI HL  IALDRYW +T  I+Y   RT  +    I   W++   I+VP           M ++     +C I    +YT+ ST  AFY P+  M+++Y           R  +   + +    +     +    C   + S F  T        S K                    +++ S+N  +K+      L + +VH     +L    T     +  +      E + K+ + RERK + T+GII   FILCW+PFF + LV+PFC   C +   +  V+ WLGY N LLNP IY  F+++F+ AFK I+  ++
Sbjct:   35 GNACVVAAIVLERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNSWTLGQVPCDIFISLDVLCCTSSILHLCAIALDRYWAITEPIDYMKKRTPRRAAVLISVTWLVGFSISVPPMLVMRSQPGSMAEDRANPKQCKIRQDPWYTIYSTFGAFYIPLTLMLVLY----------GRIFKAARFRIRRTVRKTEKKKVADSCLAISPSLFHKTPHGDAQGKSWKRSVE-------------PRPLALPSVNGAVKHAEDGESLEIIEVHSNSRGNLPLPNTPSTVPLFESRHDKATEAKRKIALARERKTVKTLGIIMGTFILCWLPFFIVALVMPFCQESCYMPRWLEDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCHF 400
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Medaka
Match: ENSORLT00000018283.2 (pep primary_assembly:ASM223467v1:22:9799933:9805173:-1 gene:ENSORLG00000014581.2 transcript:ENSORLT00000018283.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 168.703 bits (426), Expect = 1.787e-46
Identity = 125/384 (32.55%), Postives = 189/384 (49.22%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVT-RIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYF-YTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLME--NTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            + N  V+  + L + L   +N+LI S+A+TDL+V+I VM +S +Y +S  W LG   CD W+ +D+  C+ASI HL  IALDRYW +T  +EY   RTM +    +  +W+IS+ I++P  F       +   E      C++N+    YTL ST  AFY P + ++I+Y                                                G  Y+   S   K  CS  +   T + ++ +   S+ S+NS      +  + H+   S+ S    L ++ +   L  ++ E R ++   RERKA  T+GII   FI+CW+PFF  TLVL  C   C  HPI+  +  WLGYLN L+NP IYT F+ EF+ AF+ ++
Sbjct:   50 LSNAFVITTIFLTRKLHTPANFLIGSLAVTDLLVSILVMPISILYTVSKTWSLGQIVCDIWLSSDITFCTASILHLCVIALDRYWAITDALEYPKRRTMRRAAMMVGVVWVISISISMPPLFWRQAKAHEELTE------CVVNTDQISYTLYSTFGAFYVPTVLLIILY------------------------------------------------GRIYMAARSRILKTPCSSGKRFTTAQLIQTSAGSSLCSLNST-----SHQEAHLHSGSTRSGGSPLFMNSVKVKLADSVLE-RKRLCAARERKATKTLGIILGAFIVCWLPFFVGTLVLAICKE-CWFHPILFDLFTWLGYLNSLINPVIYTAFNDEFKQAFQKLI 372
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Medaka
Match: HTR1B (5-hydroxytryptamine receptor 1B [Source:HGNC Symbol;Acc:HGNC:5287])

HSP 1 Score: 151.754 bits (382), Expect = 1.603e-40
Identity = 114/382 (29.84%), Postives = 192/382 (50.26%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGY-FYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            + N  V+  +   + L   +N+LI S+A+TDL+V+I VM +SA+Y +   W LG   CD W+ +D+  C+ASI HL  IALDRYW +T  +EY   RT ++    I + W+I++ I++P  F + +++    +EV     C +N+ + FYT+ ST  AFY P + ++ +Y +I                             Y     R  +   +  G + L ++ + +    S+   T  +    D  S ++ +S      NV+ V +    +L                  +E++R  +   RE+KA  T+GII   +I+CW+PFF  TL++P C +    HP +  +  WLGYLN L+NP IYT+ +++F+ AF  ++
Sbjct:   30 LSNAFVIATIYQSRKLHTPANFLIASLAVTDLLVSILVMPISALYTVCQTWTLGQVVCDIWLSSDITCCTASILHLCVIALDRYWAITDAVEYSKKRTPARAAGMIATAWVIAISISLPP-FFWRQVKA---EEVT---SCNVNTDHIFYTIYSTFGAFYIPTLLLIALYGRI-----------------------------YVEARKRILKQSQNKPGKR-LTSARLITNSPGSVASTTSLNYGTNDTSSCDTTSSA-----NVSQVKVTVSDAL------------------LEKKR--ISAAREKKATKTLGIILGAYIICWLPFFIYTLLVPLCDS--CFHPELFDIFTWLGYLNSLINPIIYTMSNEDFKQAFHKLI 347
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Medaka
Match: adra2a (adrenoceptor alpha 2A [Source:NCBI gene;Acc:266750])

HSP 1 Score: 147.902 bits (372), Expect = 1.069e-38
Identity = 111/386 (28.76%), Postives = 181/386 (46.89%), Query Frame = 1 
Query:  346 GNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTR-IEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVH---IARMSSLSSLRTLKV---SVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNIL 1482
            GN+LVV+AV   + LR   N  ++S+A  D++VA  VM  S   E+   W+ G  WC+ ++  DV+ C+ASI HL  I+LDRYW++T+ IEY   RT  ++   I+ +W+I+ +I+ P       +E +   E  +   C IN   +Y + S + +F+ P I M+++Y        R  +  ++       D + K +           E+      D  L +  +  +    L E   R    A  + VN  + E     +    H   I + S+    R  +V      P    ++ +  R K    RE++    + ++   F++CW PFF   ++   C + C V   + +   W GY N  LNP IYTIF+ +FR AFK IL
Sbjct:   33 GNVLVVIAVFTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMGFWYFGKVWCEIYLALDVLFCTASIAHLCAISLDRYWSITQAIEYNLKRTPRRIKSIIVIVWVIAAVISFPP---LITMEKENGSESPV---CKINDEKWYVISSCIGSFFLPCIIMVLVY-------VRIYQIAKKRTRAPPGDRQQKGLSGPGAAAAGQRENGVGEP-DDGLCHEKLNGEQDVELKEGVERGADEA-KVEVNGGDMEESSSSDHKADHPCSIPKKSAKGKTRLSQVKPGDADPQRRAQSAKASRWKGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYMLKTLCSS-CYVPTALFNFFFWFGYCNSALNPIIYTIFNHDFRRAFKKIL 402
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Planmine SMEST
Match: SMESG000059571.1 (SMESG000059571.1)

HSP 1 Score: 782.711 bits (2020), Expect = 0.000e+0
Identity = 433/433 (100.00%), Postives = 433/433 (100.00%), Query Frame = 1 
Query:  217 MVHNHTVTALNSSAFPGFQLKHGXXXXXXXXXXXXXXXXXXXVGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWXXXXXXXXXXXXXXXXNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWRRCIDR 1515
            MVHNHTVTALNSSAFPGFQLKHGIIHFILTLLILETFIMLTIVGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWKIFQIAKRQIRRKRRFNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVLLWLGYLNCLLNPFIYTIFSQEFRCAFKNILTGYYWRRCIDR
Sbjct:    1 MVHNHTVTALNSSAFPGFQLKHGIIHFILTLLILETFIMLTIVGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIYWKIFQIAKRQIRRKRRFNYEVTFDSKYKSICRYFHCCHRTTESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIKYQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVLLWLGYLNCLLNPFIYTIFSQEFRCAFKNILTGYYWRRCIDR 433
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Planmine SMEST
Match: SMESG000019254.1 (SMESG000019254.1)

HSP 1 Score: 193.356 bits (490), Expect = 2.341e-54
Identity = 90/168 (53.57%), Postives = 124/168 (73.81%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY 846
            +GN+ VV A++LE+ L+N+SNYLILS+A+ DL+VAI VM +SA+ E+S+ W+LGI  CD W   DV+SC+ASI HLV IA+DRYW VT I Y H RT S++I  I+ +W+IS++I+VPSRFH HR   +  + V++ G C+IN    YT+ S + AFY PM FM +IY
Sbjct:   43 IGNVFVVAAIVLERTLKNVSNYLILSLAVADLMVAILVMPISAIKEVSSTWWLGIELCDLWTCFDVLSCTASILHLVVIAIDRYWAVTDINYLHRRTSSRIILMIIGVWLISVIISVPSRFHTHRNNAEWLR-VIVNGSCIINESVSYTVFSNLGAFYLPMAFMSVIY 209

HSP 2 Score: 83.1889 bits (204), Expect = 1.592e-16
Identity = 49/94 (52.13%), Postives = 62/94 (65.96%), Query Frame = 1 
Query: 1231 RHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYW-RRCI 1509
            R+KVE KRERKA  T+ IIT CFI+CW+PF    +   FC        +  S+ LWLGY+N  LNP IYT+FS +FR AF+ IL G+Y  RRC+
Sbjct:  418 RNKVEQKRERKAARTLAIITGCFIICWLPFGINNVAHAFCNTEPCGSALFDSLCLWLGYVNSGLNPVIYTVFSPDFRTAFRKILLGHYHTRRCL 511
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Planmine SMEST
Match: SMESG000004643.1 (SMESG000004643.1)

HSP 1 Score: 185.652 bits (470), Expect = 6.755e-51
Identity = 104/205 (50.73%), Postives = 141/205 (68.78%), Query Frame = 1 
Query:  232 TVTALNSSAFPGFQLKHGXXXXXXXXXXXXXXXXXXXVGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY 846
             +T   S     F  KHG IH  LT  +L + I+ TI+GN+ VV A++LEKNL+++SNYLILS+A+ DL+VA  VM++S + EIS +WFLGI  CDFW+  DV+ CSASI HLV IA DRYW VT I+Y   RT  ++I  I+ +W +S++I++PSRF+  R    +++ VVI G C IN  YFYT+ STV AFY PM  ++ IY
Sbjct:   10 NITKNQSLEVARFSPKHGWIHVYLTSAVLGSLILCTIIGNVFVVAAIILEKNLQSVSNYLILSLAVADLMVASLVMSVSLLSEISKQWFLGIELCDFWVCFDVLCCSASILHLVAIAFDRYWAVTNIDYIRMRTAKRIIIMIIIVWFLSIIISIPSRFYSSRTWENVYKSVVIDGLCNINDEYFYTIFSTVGAFYMPMFLLIGIY 214

HSP 2 Score: 104.76 bits (260), Expect = 2.404e-23
Identity = 59/94 (62.77%), Postives = 67/94 (71.28%), Query Frame = 1 
Query: 1219 IEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYYWR 1500
            IE+Q+ K+E KRERKA  T+ IIT CFILCW+PFF   L LPFCG  C+ + I SS  LWLGY N LLNP IYTIFS EFR AF  IL G Y +
Sbjct:  518 IEQQKQKLEHKRERKAARTLAIITGCFILCWLPFFIQALYLPFCGRQCVPNDIFSSFFLWLGYCNSLLNPIIYTIFSPEFRNAFNKILFGRYQK 611
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Planmine SMEST
Match: SMESG000008878.1 (SMESG000008878.1)

HSP 1 Score: 181.03 bits (458), Expect = 4.433e-50
Identity = 88/168 (52.38%), Postives = 118/168 (70.24%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY 846
            +GN  V+ A+LLEKNL N+SNYLI+S+A+ DL+VA  VM+LS  +EIS  WFLG+  CD W+  DV+ CSASI HLV IA+DRY  VT+ +Y   RT  ++   I  IW++S+MI+VP+RFH +R  T+  Q VV  G+CLIN    +T+ ST  AFY PM F++ IY
Sbjct:   46 IGNSFVIAAILLEKNLLNVSNYLIISLAVADLMVASLVMSLSVFHEISEAWFLGLEICDLWVCFDVLCCSASILHLVAIAIDRYMAVTKPDYVRTRTAKRIYIMIAIIWLLSIMISVPTRFHLNRNYTKEMQRVVYDGKCLINDEIGFTVFSTFGAFYLPMFFIIGIY 213

HSP 2 Score: 99.7525 bits (247), Expect = 7.122e-22
Identity = 71/182 (39.01%), Postives = 103/182 (56.59%), Query Frame = 1 
Query:  964 TTESEFSTTGDQYLINSSVKSKYTCSLME---NTVRDMKYADNI-SVNSINSEIKYQLNVN-DVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYY 1494
            + + +   + ++ L+NS  K+ +   L +      + +K  +N+ SV+ I    K +L  N   H  R S + S             ++ +E +R K+E KRERKA+ T+ IIT CFI+CW PFF    ++PFCG  C + P++SS +LWLGY N LLNP IYTIFS +FR AF  IL G Y
Sbjct:  324 SDDRKILNSNNRRLLNSDYKTIHINHLRKYILKKSKALKVNENLNSVSVIKGPTKTRLMNNISTHEHRPSRMMSQ------------SERMEYKRQKLEQKRERKAVRTLAIITGCFIVCWQPFFIQATIVPFCGKKCQLPPLLSSFVLWLGYCNSLLNPVIYTIFSPDFRDAFHKILFGRY 493
[Close]
BLAST of 5-hydroxytryptamine receptor vs. Planmine SMEST
Match: SMESG000008878.1 (SMESG000008878.1)

HSP 1 Score: 181.03 bits (458), Expect = 7.503e-50
Identity = 88/168 (52.38%), Postives = 118/168 (70.24%), Query Frame = 1 
Query:  343 VGNILVVLAVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWCDFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSIWMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFYAPMIFMMIIY 846
            +GN  V+ A+LLEKNL N+SNYLI+S+A+ DL+VA  VM+LS  +EIS  WFLG+  CD W+  DV+ CSASI HLV IA+DRY  VT+ +Y   RT  ++   I  IW++S+MI+VP+RFH +R  T+  Q VV  G+CLIN    +T+ ST  AFY PM F++ IY
Sbjct:   60 IGNSFVIAAILLEKNLLNVSNYLIISLAVADLMVASLVMSLSVFHEISEAWFLGLEICDLWVCFDVLCCSASILHLVAIAIDRYMAVTKPDYVRTRTAKRIYIMIAIIWLLSIMISVPTRFHLNRNYTKEMQRVVYDGKCLINDEIGFTVFSTFGAFYLPMFFIIGIY 227

HSP 2 Score: 99.3673 bits (246), Expect = 8.988e-22
Identity = 71/182 (39.01%), Postives = 103/182 (56.59%), Query Frame = 1 
Query:  964 TTESEFSTTGDQYLINSSVKSKYTCSLME---NTVRDMKYADNI-SVNSINSEIKYQLNVN-DVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKAIITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVXXXXXXXXXXXNPFIYTIFSQEFRCAFKNILTGYY 1494
            + + +   + ++ L+NS  K+ +   L +      + +K  +N+ SV+ I    K +L  N   H  R S + S             ++ +E +R K+E KRERKA+ T+ IIT CFI+CW PFF    ++PFCG  C + P++SS +LWLGY N LLNP IYTIFS +FR AF  IL G Y
Sbjct:  338 SDDRKILNSNNRRLLNSDYKTIHINHLRKYILKKSKALKVNENLNSVSVIKGPTKTRLMNNISTHEHRPSRMMSQ------------SERMEYKRQKLEQKRERKAVRTLAIITGCFIVCWQPFFIQATIVPFCGKKCQLPPLLSSFVLWLGYCNSLLNPVIYTIFSPDFRDAFHKILFGRY 507
The following BLAST results are available for this feature:
BLAST of 5-hydroxytryptamine receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HTR1A5.452e-5633.505-hydroxytryptamine receptor 1A [Source:HGNC Symbo... [more]
HTR1B1.440e-4431.615-hydroxytryptamine receptor 1B [Source:HGNC Symbo... [more]
HTR1F2.660e-4131.955-hydroxytryptamine receptor 1F [Source:HGNC Symbo... [more]
HTR1E3.123e-3830.695-hydroxytryptamine receptor 1E [Source:HGNC Symbo... [more]
DRD22.456e-3128.98dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ser-41.778e-5534.52SERotonin/octopamine receptor family; Serotonin re... [more]
ser-41.778e-5534.52SERotonin/octopamine receptor family; Serotonin re... [more]
ser-23.483e-3929.97Tyramine receptor Ser-2 [Source:UniProtKB/Swiss-P... [more]
ser-22.303e-3830.00Tyramine receptor Ser-2 [Source:UniProtKB/Swiss-P... [more]
ser-22.653e-3830.00Tyramine receptor Ser-2 [Source:UniProtKB/Swiss-P... [more]
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
5-HT1A2.049e-3939.43gene:FBgn0004168 transcript:FBtr0474126[more]
5-HT1A2.135e-3939.43gene:FBgn0004168 transcript:FBtr0086577[more]
5-HT1B3.293e-3940.24gene:FBgn0263116 transcript:FBtr0330055[more]
5-HT1B4.042e-3940.24gene:FBgn0263116 transcript:FBtr0086599[more]
5-HT1B4.517e-3940.24gene:FBgn0263116 transcript:FBtr0330056[more]
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
htr1aa1.055e-5232.115-hydroxytryptamine (serotonin) receptor 1A a [Sou... [more]
htr1ab3.060e-5130.415-hydroxytryptamine (serotonin) receptor 1A b [Sou... [more]
htr1ab6.089e-4931.965-hydroxytryptamine (serotonin) receptor 1A b [Sou... [more]
htr1ab6.089e-4931.965-hydroxytryptamine (serotonin) receptor 1A b [Sou... [more]
HTR78.590e-4030.635-hydroxytryptamine receptor 7 [Source:NCBI gene;A... [more]
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000046867.11.317e-4432.995-hydroxytryptamine (serotonin) receptor 1A, G pro... [more]
HTR1F3.451e-4130.005-hydroxytryptamine (serotonin) receptor 1F, G pro... [more]
HTR1E4.891e-4130.475-hydroxytryptamine (serotonin) receptor 1E, G pro... [more]
ADRA2B3.360e-4027.02adrenoceptor alpha 2B [Source:NCBI gene;Acc:100485... [more]
ENSXETT00000026158.18.164e-3325.00alpha-2Db adrenergic receptor-like [Source:NCBI ge... [more]
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Htr1a1.870e-5432.925-hydroxytryptamine (serotonin) receptor 1A [Sourc... [more]
Htr1b3.162e-4431.435-hydroxytryptamine (serotonin) receptor 1B [Sourc... [more]
Htr1b3.162e-4431.435-hydroxytryptamine (serotonin) receptor 1B [Sourc... [more]
Htr1f2.395e-4131.695-hydroxytryptamine (serotonin) receptor 1F [Sourc... [more]
Adra2c1.395e-3929.56adrenergic receptor, alpha 2c [Source:MGI Symbol;A... [more]
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BLAST of 5-hydroxytryptamine receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q25414|5HTR_LYMST1.079e-6238.055-hydroxytryptamine receptor OS=Lymnaea stagnalis ... [more]
sp|P08908|5HT1A_HUMAN2.618e-5533.505-hydroxytryptamine receptor 1A OS=Homo sapiens OX... [more]
sp|Q9N297|5HT1A_GORGO3.424e-5533.505-hydroxytryptamine receptor 1A OS=Gorilla gorilla... [more]
sp|Q9N298|5HT1A_PANTR3.495e-5533.505-hydroxytryptamine receptor 1A OS=Pan troglodytes... [more]
sp|O42385|5H1AA_TAKRU6.578e-5532.555-hydroxytryptamine receptor 1A-alpha OS=Takifugu ... [more]
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BLAST of 5-hydroxytryptamine receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A193KUL50.000e+099.77GCR090 OS=Schmidtea mediterranea OX=79327 GN=gcr09... [more]
A0A210PSA31.108e-6439.095-hydroxytryptamine receptor OS=Mizuhopecten yesso... [more]
Q2PGF52.098e-6439.095-HT receptor OS=Mizuhopecten yessoensis OX=6573 G... [more]
A0A2C9JN077.979e-6436.45G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
R7UP081.744e-6338.32G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000006138.22.016e-5131.63pep primary_assembly:Astyanax_mexicanus-2.0:6:2799... [more]
htr1ab4.716e-5132.475-hydroxytryptamine (serotonin) receptor 1A b [Sou... [more]
HTR1F1.386e-3829.585-hydroxytryptamine receptor 1F-like [Source:NCBI ... [more]
adra2b6.758e-3527.58adrenoceptor alpha 2B [Source:NCBI gene;Acc:266751... [more]
adra2a1.242e-3428.53adrenoceptor alpha 2A [Source:NCBI gene;Acc:266750... [more]
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HTR1F1.120e-4830.585-hydroxytryptamine receptor 1F [Source:HGNC Symbo... [more]
ENSPMAT00000009127.13.510e-3539.29pep scaffold:Pmarinus_7.0:GL478629:43196:44446:-1 ... [more]
ENSPMAT00000001357.12.530e-3025.96pep scaffold:Pmarinus_7.0:GL478256:17157:19157:1 g... [more]
adra2c2.116e-2834.52adrenoceptor alpha 2C [Source:NCBI gene;Acc:266752... [more]
chrm5b7.222e-2834.30cholinergic receptor, muscarinic 5b [Source:ZFIN;A... [more]
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO354505.138e-1833.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO473591.026e-1723.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO438351.622e-1725.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO329392.581e-1730.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO366101.358e-1629.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of 5-hydroxytryptamine receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000005282.23.509e-5433.07pep primary_assembly:ASM223467v1:9:8571029:8576106... [more]
htr1ab7.434e-5431.625-hydroxytryptamine (serotonin) receptor 1A b [Sou... [more]
ENSORLT00000018283.21.787e-4632.55pep primary_assembly:ASM223467v1:22:9799933:980517... [more]
HTR1B1.603e-4029.845-hydroxytryptamine receptor 1B [Source:HGNC Symbo... [more]
adra2a1.069e-3828.76adrenoceptor alpha 2A [Source:NCBI gene;Acc:266750... [more]
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BLAST of 5-hydroxytryptamine receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000059571.10.000e+0100.00SMESG000059571.1[more]
SMESG000019254.12.341e-5453.57SMESG000019254.1[more]
SMESG000004643.16.755e-5150.73SMESG000004643.1[more]
SMESG000008878.14.433e-5052.38SMESG000008878.1[more]
SMESG000008878.17.503e-5052.38SMESG000008878.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034320 ID=SMED30034320|Name=5-hydroxytryptamine receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1789bp
CTTTTTAACACCGCCATCAGTCTCCCTTTATTGGGATTCCACCAACTGTC
GGATTCCACCTACAGCAGGCGAATGCCCAAGTAAATGTCACATCGACAGT
CACTAATAAGTGATGGATACGGGTTTACTGTATCAATTCCATAATGACAT
TTTTTCAAAAAATCAACAACAAATCGGCATAGATTATTGTAAATTTATGA
AGAAAAATCAATTGAAATGGTCCACAATCACACGGTGACGGCCCTGAATT
CCAGCGCATTTCCGGGATTCCAGTTGAAACACGGGATAATTCATTTCATT
CTCACTCTGTTGATTTTGGAAACTTTTATTATGCTAACAATTGTGGGAAA
TATTCTTGTCGTTTTGGCTGTACTTTTGGAAAAGAACTTAAGAAATCTTT
CAAACTATCTGATCCTCAGTATGGCGATCACAGATTTGGTAGTAGCGATA
TTTGTAATGAATTTGAGCGCAGTTTATGAAATTTCGAACCGATGGTTTTT
GGGTATAGCATGGTGTGATTTCTGGATATTTACTGATGTTATGAGCTGTT
CGGCTTCAATCTTCCATTTGGTCACAATAGCCCTAGATAGGTATTGGACA
GTGACCAGAATCGAGTATAAACACAATCGCACAATGTCACAATTGATTTT
CACAATTCTTTCGATTTGGATGATTTCTCTCATGATTGCAGTTCCTTCTA
GATTTCATTTCCACAGACTAGAAACACAAATGTTCCAGGAAGTCGTAATA
AAAGGACGATGTTTAATCAACAGCGGTTATTTCTATACTTTGCTATCAAC
GGTCATTGCTTTCTACGCTCCAATGATTTTTATGATGATAATATATTGGA
AAATATTCCAAATAGCTAAGCGGCAAATCAGACGGAAACGGAGGTTCAAC
TATGAAGTTACTTTTGACTCAAAATACAAATCAATCTGCCGATATTTCCA
CTGCTGTCACAGGACAACTGAATCAGAGTTCTCTACAACTGGAGACCAAT
ACCTTATCAATAGCAGTGTGAAAAGTAAATACACTTGCAGTTTGATGGAG
AACACCGTCAGGGATATGAAATACGCTGATAACATATCTGTCAATTCTAT
AAATTCCGAAATAAAATACCAACTGAATGTCAACGATGTTCATATTGCAA
GGATGAGCAGTCTTTCATCTTTGAGAACGTTGAAAGTTTCAGTTATGCCC
TACAACCTAACGAAAACTATCGAAGAGCAACGACACAAAGTCGAAGTGAA
ACGTGAAAGAAAGGCTATAATCACTGTCGGCATAATTACTTGCTGTTTTA
TTCTCTGTTGGATGCCGTTTTTCACGTTGACTTTAGTTTTACCATTTTGT
GGCGCGTATTGTATTGTTCATCCGATTATTTCATCAGTTTTACTTTGGCT
TGGTTATTTGAATTGTCTTCTTAATCCTTTTATTTATACAATATTTTCTC
AAGAGTTTAGATGTGCTTTTAAAAACATTTTGACTGGTTATTATTGGAGG
AGATGTATTGATAGATAAACTCTAGAAAATAATTGGTGATCTTATTTATT
TCAATTGACTTAGACTTCACGGTTCAATTAATGATTTGAATACTGCATGA
ATTGCTATAACCCTTTAACAAACGTTCACGAGACTCAGAAGAATAAAGAA
AGATAAATATAATTCATTAAAATGCCAGCATTTACCTCATTACGATGAGA
TAGACAGAAAAACATATTTTAATTTTAAGTGAAGACCTTCGCGATGAATT
CATCCGCTGTAATTGAAAATCAAGACGAAGGCGAAAGAT
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protein sequence of SMED30034320-orf-1

>SMED30034320-orf-1 ID=SMED30034320-orf-1|Name=SMED30034320-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=434bp
MVHNHTVTALNSSAFPGFQLKHGIIHFILTLLILETFIMLTIVGNILVVL
AVLLEKNLRNLSNYLILSMAITDLVVAIFVMNLSAVYEISNRWFLGIAWC
DFWIFTDVMSCSASIFHLVTIALDRYWTVTRIEYKHNRTMSQLIFTILSI
WMISLMIAVPSRFHFHRLETQMFQEVVIKGRCLINSGYFYTLLSTVIAFY
APMIFMMIIYWKIFQIAKRQIRRKRRFNYEVTFDSKYKSICRYFHCCHRT
TESEFSTTGDQYLINSSVKSKYTCSLMENTVRDMKYADNISVNSINSEIK
YQLNVNDVHIARMSSLSSLRTLKVSVMPYNLTKTIEEQRHKVEVKRERKA
IITVGIITCCFILCWMPFFTLTLVLPFCGAYCIVHPIISSVLLWLGYLNC
LLNPFIYTIFSQEFRCAFKNILTGYYWRRCIDR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004993G-protein coupled serotonin receptor activity
GO:0004930G-protein coupled receptor activity
GO:0004871signal transducer activity
Vocabulary: cellular component
TermDefinition
GO:0005887integral component of plasma membrane
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0098664G-protein coupled serotonin receptor signaling pathway
GO:0007186G-protein coupled receptor signaling pathway
GO:0007165signal transduction
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002056medial muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 107..129
score: 35.21
coord: 62..83
score: 28.86
coord: 389..415
score: 34.89
coord: 142..163
score: 21.05
coord: 191..214
score: 24.59
coord: 29..53
score: 25.93
coord: 350..374
score: 29.31
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 44..407
e-value: 4.5E-61
score: 206.5
IPR000276G protein-coupled receptor, rhodopsin-likePROSITEPS00237G_PROTEIN_RECEP_F1_1coord: 113..129
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 36..421
e-value: 1.9E-89
score: 302.4
NoneNo IPR availableGENE3DG3DSA:1.20.120.10coord: 222..343
e-value: 1.9E-89
score: 302.4
NoneNo IPR availablePANTHERPTHR242475-HYDROXYTRYPTAMINE RECEPTORcoord: 28..423
NoneNo IPR availablePANTHERPTHR24247:SF1985-HYDROXYTRYPTAMINE RECEPTOR 2A-RELATEDcoord: 28..423
NoneNo IPR availableCDDcd153317tmA_5-HT1A_invertebratescoord: 28..418
e-value: 6.52281E-89
score: 268.838
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 4..429
NoneNo IPR availableTMHMMTMhelixcoord: 61..83
NoneNo IPR availableTMHMMTMhelixcoord: 387..409
NoneNo IPR availableTMHMMTMhelixcoord: 23..54
NoneNo IPR availableTMHMMTMhelixcoord: 350..372
NoneNo IPR availableTMHMMTMhelixcoord: 143..165
NoneNo IPR availableTMHMMTMhelixcoord: 192..214
NoneNo IPR availableTMHMMTMhelixcoord: 103..122
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 44..407
score: 40.031