FMRFamide-activated amiloride-sensitive sodium channel

Query:  271 GLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPN-----ELTLMMFHDKIENYYMNIDY-----------DFSLKI--SHGTEMLKYCA--IFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQT-----------ITSLIILVSLTPAADIP-ELKNSFLMDI--------LERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCK-NG-QSPIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            G+ I+ YL++  +  +   F    +FPA+T+C+ +PF         K      E   ER+    +   N T++ N        L++  ++  ++ M +D              S KI  +HG +M    A  IF+          +  + ++VE      Q    C    +  NY   T           I +  +     P+A+   E     ++DI        L    G++L++HE  SYP I +EGI    G   +I     K  R   P   C  NG + P+ +    +N  YS   C+    Q  +I  C C + L+P P    EK  YC N    + +       C  D  M+V   +++     C + CN   Y   +S+  W
Sbjct:   68 GIFIRTYLSWEVSVSLSVGFK-TMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLATNIFA----------QVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPR--GEK--YCNNRDFPDWAH------CYSDLQMSVA--QRETCIGMCKESCNDTQYKMTISMADW 435          

Query:  271 GLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPN-----ELTLMMFHDKIENYYMNIDY-----------DFSLKI--SHGTEM-LKYCAI----------------FSDGLIIITYN--CETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQT-----------ITSLIILVSLTPAADIP-ELKNSFLMDI--------LERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCK-NG-QSPIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            G+ I+ YL++  +  +   F    +FPA+T+C+ +PF         K      E   ER+    +   N T++ N        L++  ++  ++ M +D              S KI  +HG +M ++ C++                 ++  I+   N   +  + ++VE      Q    C    +  NY   T           I +  +     P+A+   E     ++DI        L    G++L++HE  SYP I +EGI    G   +I     K  R   P   C  NG + P+ +    +N  YS   C+    Q  +I  C C + L+P P    EK  YC N    + +       C  D  M+V   +++     C + CN   Y   +S+  W
Sbjct:   68 GIFIRTYLSWEVSVSLSVGFK-TMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPR--GEK--YCNNRDFPDWAH------CYSDLQMSVA--QRETCIGMCKESCNDTQYKMTISMADW 462          

Query:  271 GLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPN-----ELTLMMFHDKIENYYMNIDY-----------DFSLKI--SHGTEM-LKYCAI----------------FSDGLIIITYN--CETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQT-----------ITSLIILVSLTPAADIP-ELKNSFLMDI--------LERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCK-NG-QSPIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            G+ I+ YL++  +  +   F    +FPA+T+C+ +PF         K      E   ER+    +   N T++ N        L++  ++  ++ M +D              S KI  +HG +M ++ C++                 ++  I+   N   +  + ++VE      Q    C    +  NY   T           I +  +     P+A+   E     ++DI        L    G++L++HE  SYP I +EGI    G   +I     K  R   P   C  NG + P+ +    +N  YS   C+    Q  +I  C C + L+P P    EK  YC N    + +       C  D  M+V   +++     C + CN   Y   +S+  W
Sbjct:  113 GIFIRTYLSWEVSVSLSVGFK-TMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPR--GEK--YCNNRDFPDWAH------CYSDLQMSVA--QRETCIGMCKESCNDTQYKMTISMADW 507          

Query:  679 VFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW-----------VPSYEKLFRIADLINKTE-----IYLKNHRERESKEDYISYIQANITN 1440
            +F H    NCYT    +N   +TI S  +  S      I  +        L    G K++IH  + YP +E+ G +++   + +I     +  + S P  +C    S +  ++  +N  YS   C++   Q K++E CGC  A + +P  P     YC    H N    +  L  A       + L  Q   + C + C++  +    S+ +W           V ++++  ++   +NKT+     I+ K+  +R   E   + I+  ++N
Sbjct:  274 LFHHPMHGNCYTF---NNRENETILSTSMGGSEYGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMVTSIGMHLTESFKLSEPYSQCTEDGSDV-PIRNIYNAAYSLQICLHSCFQTKMVEKCGC--AQYSQPLPP--AANYCNYQQHPNWMYCYYQLHRA----FVQEELGCQ---SVCKEACSFKEWTLTTSLAQWPSVVSEKWLLPVLTWDQGRQVNKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSN 530          

Query:  838 GEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLF----RIADLINKTEIYLKNHRE 1389
              G++LV+HE +  P  +  G     G +++   +  +  R S P   C +   P+  +  + +YS   C     QLK++E CGC +  FP   +P+E+  +C N   +   Q  +NL      T +        E  +C Q C+   + T  S + W     K+      ++D+ N TE   + +R+
Sbjct:  485 AAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDTFRPVPYIYNE-HYSPEGCHRNCFQLKVLEICGCGDPRFP---LPSEEHRHC-NAKSKIDRQCLSNL------TSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNFKIGTDCPAVSDIFNDTEACTEYYRQ 661          

Query:  838 GEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLF----RIADLINKTEIYLKNHRE 1389
              G++LV+HE +  P  +  G     G +++   +  +  R S P   C +   P+  +  + +YS   C     QLK++E CGC +  FP   +P+E+  +C N   +   Q  +NL      T +        E  +C Q C+   + T  S + W     K+      ++D+ N TE   + +R+
Sbjct:  487 AAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDTFRPVPYIYNE-HYSPEGCHRNCFQLKVLEICGCGDPRFP---LPSEEHRHC-NAKSKIDRQCLSNL------TSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNFKIGTDCPAVSDIFNDTEACTEYYRQ 663          

Query:  838 GEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLF----RIADLINKTEIYLKNHRE 1389
              G++LV+HE +  P  +  G     G +++   +  +  R S P   C +   P+  +  + +YS   C     QLK++E CGC +  FP   +P+E+  +C N   +   Q  +NL      T +        E  +C Q C+   + T  S + W     K+      ++D+ N TE   + +R+
Sbjct:  446 AAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDTFRPVPYIYNE-HYSPEGCHRNCFQLKVLEICGCGDPRFP---LPSEEHRHC-NAKSKIDRQCLSNL------TSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNFKIGTDCPAVSDIFNDTEACTEYYRQ 622          

Query:  838 GEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLF----RIADLINKTEIYLKNHRE 1389
              G++LV+HE +  P  +  G     G +++   +  +  R S P   C +   P+  +  + +YS   C     QLK++E CGC +  FP   +P+E+  +C N   +   Q  +NL      T +        E  +C Q C+   + T  S + W     K+      ++D+ N TE   + +R+
Sbjct:  486 AAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDTFRPVPYIYNE-HYSPEGCHRNCFQLKVLEICGCGDPRFP---LPSEEHRHC-NAKSKIDRQCLSNL------TSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQNFKIGTDCPAVSDIFNDTEACTEYYRQ 662          

Query:  100 RKSESNVLVIDKNAFNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKF-DDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVV--------IDEVNTTKDPNELT-LMMFHDK--IENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQT-SNYSQQTITSLIILVSLTPAADIPE-----------LKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHS-TPPQKCKN-GQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALF 1107
            +K+E  + V  K     FCE +++ G  +I K   +F K+ W+  V     LL     +L   YL+      V     +D  EFP++T+C+  P          +    +P+M    +             D+ +  K   EL      H    ++ ++M+  +D S       +++K C+   +     +++C +     +  +         C+T+  + S  ++QT   +   +SLT  A++ E           L NSF+        G +  +H  ++ P +  +   V P   N++ Y  +   R+   PP    N  +   + ++   +Y+   C++       +  CGC  AL+
Sbjct:   58 QKAEGTISV--KRETQHFCETTTMHGPKRIFKGKRIFTKLFWLIMVLGSLGLLIYQCWILSASYLSKPIVSQVSFLIPEDGMEFPSVTVCNFTPIRKSYIEAMNRTGDVSPDMINYLMNWFTEIPILLGNTDQQSLNKGNEELREYQSIHPNFTVDQFFMDASFDCS-------DLMKLCSFQGE-----SFDCCSLASPTLTPVG-------KCFTLDLSKSPMNKQTEPGIRAGLSLTLDANLDEQFDSSTGIDALLPNSFV-------NGFRYFVHPKDTIPNLASDEYTVSP---NSVAYSAISKFRYVLLPPNDWGNCTEDYPYGIQSNLSYTSGNCLSLCKAKYFMNQCGCTPALY 388          

Query:  670 EKIVFSHQKFFNCYTI----QQTSNYSQQTIT--SLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSF--CMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNL-KCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW---VPSYEKLFRIADLINKT 1362
            E + F H  + NC+TI    ++ S YS +      L I+V      ++P         +L +  G +++IH PN  P +E +G D++PG  N+I  +  +  R      +C +  S +  +K  +N S++   C+N   Q K+IE CGC    +P P      + YC    H +    F  L +   D T+           T+C ++C    Y+      KW   V   +KL  + +  N T
Sbjct:  252 EYVHFHHPIYGNCFTINNHWKENSWYSSRPGKQYGLSIVVKTDLHDNMP---------LLSQAAGARIMIHNPNQPPLVEHQGFDIRPGTENSISVKQEEAIRLGGKYSQCTSDGSDL-GIKILYNTSYTMQACLNSCFQYKMIEVCGCGYYFYPLP----PGMEYCNYNKHPDWGYCFYQLYEKMLDHTLICF--------TQCPKQCKQTEYHLSAGTAKWPSPVSKAKKLLSLQERYNST 472          

Query:  670 EKIVFSHQKFFNCYTI----QQTSNYSQQTIT--SLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSF--CMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNL-KCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            E + F H  + NC+TI    ++ S YS +      L I+V      ++P         +L +  G +++IH PN  P +E +G D++PG  N+I  +  +  R      +C +  S +  +K  +N S++   C+N   Q K+IE CGC    +P P      + YC    H +    F  L +   D T+           T+C ++C    Y+      KW
Sbjct:  252 EYVHFHHPIYGNCFTINNHWKENSWYSSRPGKQYGLSIVVKTDLHDNMP---------LLSQAAGARIMIHNPNQPPLVEHQGFDIRPGTENSISVKQEEAIRLGGKYSQCTSDGSDL-GIKILYNTSYTMQACLNSCFQYKMIEVCGCGYYFYPLP----PGMEYCNYNKHPDWGYCFYQLYEKMLDHTLICF--------TQCPKQCKQTEYHLSAGTAKW 452          

Query:  820 MDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNI--KYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRP 1116
            M +L +  G +++IH PN  P +E +G D++PG   +I  K + V+       P    +G +    L    +Y+   C+N   Q K+ ETCGC    +P P
Sbjct:  299 MPLLSQAAGARIMIHNPNQPPRVEHQGFDIRPGTETSIGVKQDEVRHLGGKYGPCA-SDGNNLGLKLLYSTSYTLQACLNSCFQYKMTETCGCGYYFYPLP 398          

Query:  697 FFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGL---------KLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCK-NGQS-PIFDLKRQFNYSFSF--CMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            + NCY      N+ Q+    +    S  P AD   LK   ++DI E+GE L         +L++H+  S+P +++ GI   PG   +I     +      P   C  NG   P+ +L  +FN S+S   C+    Q ++++TCGC +  +P   +PN    YC N  + +    +  L+ +     +  +L        C Q CN   Y   +S+  W
Sbjct:  287 YGNCYIF----NWGQEGEDPM---ASANPGADF-GLK--LVLDI-EQGEYLPYVQTTAAARLILHQQRSFPFVKDLGIYAMPGTETSIAVLVDQLEHMEAPYSSCTVNGSDIPVQNLYAEFNSSYSIQSCLRSCYQEQMVQTCGCADYQYP---LPNGS-EYCSNDKYPDWVPCYYGLRDSVADRESCISL--------CQQPCNDTQYKMVISMADW 481          

Query:  811 SFLMDILERGEGL---------KLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCK-NGQS-PIFDLKRQFNYSFSF--CMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
              ++DI E+GE L         +L++H+  S+P +++ GI   PG   +I     +      P   C  NG   P+ +L  +FN S+S   C+    Q ++++TCGC +  +P   +PN    YC N  + +    +  L+ +     +  +L        C Q CN   Y   +S+  W
Sbjct:  284 GLVLDI-EQGEYLPYVQTTAAARLILHQQRSFPFVKDLGIYAMPGTETSIAVLVDQLEHMEAPYSSCTVNGSDIPVQNLYAEFNSSYSIQSCLRSCYQEQMVQTCGCADYQYP---LPNGS-EYCSNDKYPDWVPCYYGLRDSVADRESCISL--------CQQPCNDTQYKMVISMADW 450          

Query:  829 LERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCK-NGQS-PIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            L    G +L++HE  +YP I EEGI    G   +I     K  R   P   C  NG    I +L   +N  YS   C++   Q  +I  C C + L+P P    E   YC N    + +  + NL+        +   +++   + C + CN   Y   +S+  W
Sbjct:  308 LASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLVDKLQRKGEPYSPCTMNGSDVAIKNLYSVYNTTYSIQACLHSCFQDHMIRNCSCGHYLYPLP----EGEKYCNNRDFPDWAYCYLNLQ--------MSVTQRETCLSMCKESCNDTQYKMTISMADW 460          

Query:  535 YYMNIDYDFSLK----ISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQS--PIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW-----------VPSYEKLFRIADLINKTE-----IYLKNHRERESKEDYISYIQANITN 1440
            +YMNI     L+    +S+  E L     F DG+     +C+          +F H  + NCYT    +N    TI S  +  S      I  +        L    G K+++H+ N YP IE+ G +++     +I     +  + S P  +C    S  P+ ++     YS   C+    Q K++E CGC  A + +P  P     YC    H N   ++   +  Q F    + L  Q   + C Q C++  +    S+ +W           V ++++  +I   +NKT+     I+ K+  +R   E   + I+  ++N
Sbjct:  239 HYMNIMAQVPLEKKINMSYSAEELLVTCFF-DGM-----SCDARN-----FTLFHHPMYGNCYTF---NNRENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGAKVLVHQQNEYPFIEDVGTEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTNIYNA-AYSLQICLYSCFQTKMVEKCGC--AQYSQPLPP--AANYCNYQQHPN--WMYCYYQLYQAFVR--EELGCQ---SVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSN 536          

Query:  829 LERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCK-NGQS-PIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            L    G +L++HE  +YP I EEGI    G   +I     K  R   P   C  NG    I +L   +N  YS   C++   Q  +I  C C + L+P P    E   YC N    + +  + NL+        +   +++   + C + CN   Y   +S+  W
Sbjct:  308 LASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLVDKLQRKGEPYSPCTMNGSDVAIKNLYSVYNTTYSIQACLHSCFQDHMIRNCSCGHYLYPLP----EGEKYCNNRDFPDWAYCYLNLQ--------MSVTQRETCLSMCKESCNDTQYKMTISMADW 460          

Query:  130 DKNAFNLFCEISS---IRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTE-MLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTI---QQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMD--ILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYC--------MNLTHRNSSQIFTN----------LKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNH 1383
            +++A ++  E+ S     G+ KI  +     KV+W   V    +   L   LL++ YL +        K     ++P++++C+  P SLR        N     +   R  Q    E ++           F + I  +Y N+  D + K+SH  E ML +C                E   V     F    +FNC+T    Q+   ++      L ++ S+     +P     +  D  IL    G+++V+H P S P   + GID+ PG  +++  + +   R   P   C N    + +  +Q+ Y+F  C+    Q  +I+ CGC ++  P   +P+    +C        +N  H N     +           L C +    N+   +    +  C Q C+  +Y   +S++ W   + +L  +     +     +NH
Sbjct:   36 NRSAIDIIAELGSESNAHGLAKIVTSRDTKRKVIWALLVIAGFTAATLQLSLLVRKYLQFQVVELSEIKDSMPVQYPSVSICNIEPISLRTIRRMYFNNESQNLITWLRFIQKFRFEQDS-----------FMNSIRAFYENLGQD-AKKLSHNLEDMLMHCRF------------NRELCHVSNFSTFFDGNYFNCFTFNSGQRLQMHATGPENGLSLIFSVEKDDPLPGTYGVYNFDNNILHSA-GVRVVVHAPGSMPSPVDHGIDIPPGYSSSVGLKAILHTRLPYPYGNCTND---MLNGIKQYKYTFFACLQLCKQRLIIQRCGCKSSALPE--VPSYNATFCGVIKDWQEINRNHSNEDHNQSEEDRAFIPTPYLACEEREQKNLNNDRTYELSCGCFQPCSETSYLKSVSLSYWPLEFYQLSAVERFFKQERQAGQNH 450          

Query:  133 KNAFNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRA-------------NSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMF----HDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW-----------VPSYEKLFRIADLINKTE-----IYLKNHRERESKEDYISYIQANITN 1440
            K     +C  ++  G  +I  +     ++LWI F     +L+     LL+  +  Y  +  ++  F    +FPA+T+C+ NP+                  +L      P     RE      I E    +  + + L++F      K  +++          I H    + +  I S  ++    N            +F H    NCYT    +N   +TI S  +  S      I  +        L    G K++IH  + YP +E+ G +++   + +I     +  + S P  +C    S +  ++  +N  YS   C++   Q K++E CGC  A + +P  P     YC    H N    +  L  A       + L  Q   + C + C++  +    S+ +W           V ++++  ++   +NKT+     I+ K+  +R   E   + I+  ++N
Sbjct:   26 KELMRWYCLNTNTHGCRRIVVSRGRLRRLLWIGFTLTAVALILWQCALLVFSF--YTVSVSIKVHFR-KLDFPAVTICNINPYKYSTVRHLLADLEQETREALKSLYGFPESRKRREAESWSSISEGKQPRFSHRIPLLIFDQDEKGKARDFFTGRKRKVGGSIIHKASNVMH--IESKQVVGFQLNF----------TLFHHPMHGNCYTF---NNRENETILSTSMGGSEYGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMVTSIGMHLTESFKLSEPYSQCTEDGSDV-PIRNIYNAAYSLQICLHSCFQTKMVEKCGC--AQYSQPLPP--AANYCNYQQHPNWMYCYYQLHRA----FVQEELGCQ---SVCKEACSFKEWTLTTSLAQWPSVVSEKWLLPVLTWDQGRQVNKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSN 466          

Query:  844 GLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKC-KNGQS-PIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            G +L++HE  SYP I+EEGI    G   +I     K  R   P  +C KNG   PI +L   +N  YS   C+    Q  +I  CGC + L+P P     K  YC N    + +  ++ L+        +   +++     C + CN   Y   +S+  W
Sbjct:  316 GARLMLHEQRSYPFIKEEGIYAMAGMETSIGVLVDKLQRKGEPYSQCTKNGSDVPIQNLYSNYNTTYSIQACIRSCFQEHMIRECGCGHYLYPLP----HKRKYCNNQEFPDWAHCYSALR--------ISLAQRETCIYACKESCNDTQYKMTISMAVW 463          

Query:  766 LVSLTPAADIPELKNSFLMDI--------LERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCK-NGQS-PIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            L S  P A   E     ++DI        L    G +L++HE  S+P +++ GI    G   +I     +  R   P   C  NG   P+ +L  ++N  YS   C+    Q ++ ETCGC + LFP P    E + YC +    + +  +++L+ +           +Q+    C + CN   Y   +S+  W
Sbjct:  301 LFSSNPGA---EFGLKLILDISQQDYIPYLTSTAGARLMLHEQRSFPFLKDLGIYAMSGTETSIGVLVDELERMGFPYSDCTMNGSDVPVKNLYNEYNTTYSIQACLRSCFQAQMFETCGCGHYLFPLP----EGVSYCNSEDDPDWAYCYSSLRSSIG--------HRQFCIDSCKETCNDIQYKMTISMADW 479          

Query:  682 FSH---QKFFNCYTIQQTSNYSQQTITSLIILVSLTPAAD-----IPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCK-NGQS-PIFDLKRQFNYSFSF--CMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            F+H     + NCY      N+ Q+   ++    S  P AD     + +++    +  L+     +L++H+  S+P +++ GI   PG   +I     +      P   C  NG   P+ +L  +FN S+S   C+    Q ++++TC C +  +P   +PN    YC N+ H +    + +L+ +     N  +L        C Q CN   Y   +S+  W
Sbjct:  280 FTHIYDADYGNCYIF----NWGQEGENTM---SSANPGADFGLKLVLDIEQGEYLPFLQTTAAARLILHQQRSFPFVKDLGIYAMPGTETSISVLVDQLEHMEAPYSSCTVNGSDIPVQNLYAEFNSSYSIQSCLRSCYQEEMVKTCKCAHYQYP---LPNGS-EYCTNMKHPDWVPCYYSLRDSVAIRENCISL--------CQQPCNDTHYKMVISMADW 482          

Query:  133 KNAFNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPF---IPNEKIGYCMNLTH--RNSSQI---FTNLKCAQDFTMNVKTLKKQW-ENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISYIQANITNSY--INSSFL---------DLENENKFTYISLSRKTRNTVIKDEELVRSCH---SNVTNRWSVFI 1593
            +N F+LFCE++SIRG+ +I KAPT F +V+W AFV  MT  LF+  G L +D+L+Y TAWH RT   D + FPAIT+C+HNPFSL AN++WKK     P  F +RL ++ ++ +    D  E   +M  D  ENYY N+  + S  +SH T+M  +C + +DG+ I+  NC  E D    K  FSH ++FNC+T++  +N+S +    L +L+ L P+ +I E KN+F+MD   RGEG+KLV+HE  +YPEI+++GI+VQPG+MN + ++ +KW R  TP   C     PIFD+   + Y  + C++  LQ   I +CGC+N+ +PR     + N KI YC  L    +N   +      L CA D    VK LK++      C+  C+Y+TY    SIT W P  EKL    +   + E    N ++   KE +I Y++  + +S   INSS +         + ENE  +TYISL R + +T +++E L+   +   S V    S+F+
Sbjct:    5 RNNFDLFCELTSIRGLQRIKKAPTFFGRVIWSAFVIAMTLSLFITIGFLARDFLSYNTAWHARTIIGDKANFPAITVCAHNPFSLEANTIWKKNEILTPTGFNKRLSEITLEFIK--HDKLEYASVMLLDSTENYYANLRPNESQTLSHQTDMFPHCMVTADGVRILAENCAVEADTGFTKRYFSHPRYFNCWTLETAANHSTRETVRLTLLIRLVPSVEIDEAKNNFIMDTFSRGEGVKLVVHESGTYPEIDKDGINVQPGRMNELSFQTIKWVRLQTPIAPCLEDPKPIFDMGSTYTYRLTQCLDSILQNISINSCGCLNSEWPRTVDSALVNTKIPYCSALPKDPKNPDSLKDMVERLTCAGDLLHRVKELKEEAIRQRNCISACSYYTYPVSASITSWKPMPEKLNYFTEKCQRVESLQNNPQQ---KEKFIRYLERTLNSSSADINSSTITSLSSKFAKNFENEGLYTYISLVRTSYDTTLQEERLIFDFYILISRVGGLCSIFV 509          

Query: 1544 LLDLAILMSRIGGLCSLFIGLTVSFFIELVEFGYLICRKYSFQKGSLGAKRINNNKRQISELN 1732
            + D  IL+SR+GGLCS+F+GLT +F +EL+EF YL+CR+Y  Q  ++  K +   + + +E+N
Sbjct:  491 IFDFYILISRVGGLCSIFVGLTAAFLVELIEFIYLVCRQYKKQDSNVKKKDMELGQTENNEIN 553          

Query:  121 LVIDKNAFNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIP---NEKIGYCMNLTHRNSSQ-----IFTNLKCAQDFTMNVKTLKKQW-ENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISYI------QANITNSYINSSFL---DLENENKFTYISLSRKTRNTVIKDEELVRSCH---SNVTNRWSVFIIHRAYCVV 1617
            +V   + F +FC+++SIRG  +I +A T F++++W  FV  MT  L +  G L +D+ ++ T+WH RT  DD ++FPAIT+C+HNPFSL AN +W + +   P  F  +L  + +  +       E   ++  D  + Y+ N+  + S ++ H T M  +C + +DG+ I+  NC  E D    K  FSH K+FNC+TI+  +N S +    L +L+SL P+ +I E + +F+MD   RGEG+KLV+H+  +YPEI++ GI+VQPG+MN + +    W R  TP   C +   PI D+ RQ++Y  + C++  LQ   I  CGC+N+ +PRP  P   N KI YC  L    S       I   L C  +   N+K +K+    N  C  +C++FTY    SIT W P  EKL    D   + E  L N+ +   +E  I Y+      Q  ++   I+ S L   D +N+  +TYISL R T +T  K+E L+   +   S V    S+FI   A  +V
Sbjct:    1 MVQKPSKFAIFCDLTSIRGFQRIKRAQTPFIRMIWTLFVILMTGALIVTIGFLARDFFSFTTSWHSRTLIDDKTDFPAITICAHNPFSLEANRIWAEASILTPTEFNRQLSAMTLAFIENGNP--EYAGLLLQDSTDTYFANLRPEESQRLGHQTTMFPHCMVTADGVNIVAENCMIEGDTGFTKKRFSHPKYFNCWTIETAANQSTKDTVRLTVLLSLIPSKEINESRKNFIMDTFSRGEGVKLVVHQSGTYPEIDKHGINVQPGRMNELSFNTEWWVRLKTPTAPCLDDPPPITDMGRQYSYRMTQCLDSYLQNISINQCGCLNSEWPRPIHPDLVNSKIPYCSALPKNVSDSATLEGIIRRLNCTSNLLHNLKKIKESAILNHICTPRCSFFTYPISASITSWQPIPEKLQHFTDKFKRVERLLNNYDDPLERERLIQYLKEVIDPQEKLSTQIISKSSLRIEDFQNQGSYTYISLVRTTYDTTYKEERLIFDIYILISRVGGLCSIFIGLTAAIIV 518          

Query:  151 FCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPF---IPNEKIGYCMNLTH-----RNSSQIFTNLKCAQDFTMNVKTLKKQ-WENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISYIQANITNSYINSSFLDLENENK--------------FTYISLSRKTRNTVIKDEELV 1548
            F EISSIRG+  I++A T F++ LWI FV  MTSLL + +  LI+DYL Y T WH RT  DD + FP+ITLC+HNPFSL AN  W++ + PNP+    R  ++  + +        + L++  D IE +Y N+D      I H  EM  +C + S+   I+   C+ E D  +     SH K+FNC+TI+  +  + + IT LI+L+ L P+  I E   SF+MD   RGEG+  V+HEP +YPEIE+ GI++QP +MN I Y+PV W R +TP   C +   PI DL   + Y+   C+N  LQ +L+  CGC+N  +PRP     P     YC +L         +S++    +C  +    +K +K++     +C+ +C+YFTY   LS+T W P+   L    +   K +  LK H        ++SY  A+I       S LDLE+ N+               TYISL+R+   T + DE LV
Sbjct:   72 FGEISSIRGVQNISRAETPFIRSLWILFVITMTSLLTIFSSFLIRDYLLYETNWHTRTLRDDKTAFPSITLCAHNPFSLEANRFWREGSTPNPKQINSRFTEIATEVLRQRNVAFSINLLLL-DSIETFYTNLDPKVRYNIGHKMEMFPHCMVTSESAHIVAEKCKLELDTELHLHRISHPKYFNCWTIEGKALEATKEITRLIMLIQLVPSKKINEANLSFIMDTFTRGEGVISVVHEPGTYPEIEKHGINIQPNRMNQIIYKPVLWNRLATPKAPCSDHPPPISDLGVNYTYTQGQCLNTVLQEQLLARCGCLNTEYPRPASTDFPVNPTPYCTSLNESLTNPEMASKLIERFQCIGEVMDRLKEIKEEAARQGRCLPRCSYFTYENRLSVTLWDPNAHNLAAYTERYRKLDGLLKAHSSMNLTTSFVSYWNASIQ----QFSSLDLESHNQPERFAEYSQFVDGSVTYISLTRQEFETTVMDERLV 555          

Query:  148 LFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEK---IGYCMNLTHRNSSQIFT------NLKCAQDFTMNVKTLKKQWENTK-CMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISYIQANI------TNSYINSSFLDLE--NENKFTYISLSRKTRNTVIKDEELV 1548
            LF EISSIRG+ +I +A T F++ LWI FV  MT LL + + +LI DYL Y T+WH R+  DD SEFPAITLC+HNPFSL+AN LW   +  +P   +  +  V ++ +N  K  + + +M   D  E YY N+  + S KISH  E++ +C ++S    ++   CE E    + +  FSH K+FNC TI+   N S   I+ L++L  L P++ I + +++F+MD   RGEG+K+VIHE N+YP+IE  G +VQP +MN I YE + W R STP   CK+ Q PI DL   + Y  S C++   Q ++I  CGCMN+ +PRP         + YC ++  RNSS   T       L C++ F   +  ++++      C+ +C +FTY+T+LS+T W PS  KL          E YL    E + KE   S++Q+ I       +   N    D +   +  +TYISL R+  +T +K+E+LV
Sbjct:   75 LFGEISSIRGVQRIFRAETPFIRTLWILFVISMTCLLTVSSFMLIVDYLQYTTSWHTRSLPDDKSEFPAITLCAHNPFSLKANKLWSTGHVISPNQVKSNMAAVSLEMLNQDKVEDSV-IMALSDSFEFYYTNLSPEDSQKISHDFEIIPHCILYSPEHTVVAEKCEMENVTAMVRRTFSHPKYFNCLTIEGGGNESTSDISRLVLLAHLVPSSKIVQARSAFIMDTFTRGEGIKVVIHERNTYPQIERYGFNVQPNRMNEIIYETLSWKRLSTPVAPCKDSQPPISDLGVNYTYETSQCLDIATQEEMIRRCGCMNSEWPRPTRAVHGPRLVPYCTSM-DRNSSVEVTATVLSERLACSRIFFEELPVIRERIIRAGICIPRCRFFTYDTKLSVTSWEPSPVKLSSYTANYRIVEEYLTEPIESKKKE-LSSFLQSIIDPTLDSADEQWNKRIGDYKQFGDGTYTYISLIRRDFDTTLKEEKLV 556          

Query:  151 FCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPF---IPNEKIGYCMNLTH-----RNSSQIFTNLKCAQDFTMNVKTLKKQ-WENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISYIQANITNSYINSSFLDLENENK--------------FTYISLSRKTRNTVIKDEELV 1548
            F EISSIRG+  I++A T F++ LWI FV  MTSLL + +  LI+DYL Y T WH RT  DD + FP+ITLC+HNPFSL AN  W++ + PNP+    R  ++  + +        + L++  D IE +Y N+D      I H  EM  +C + S+   I+   C+ E D  +     SH K+FNC+TI+  +  + + IT LI+LV L P+  I E   SF+MD   RGEG+  V+HEP +YPEIE+ GI++QP +MN I Y+PV W R +TP   C     PI DL   + Y+   C+N  LQ +L+  CGC+N  +PRP     P     YC +L         +S++    +C  +    +K +K++     +C  +C+YFTY   LS+T W P+   L    +   K +  LK       K  ++SY  A+I       S LDLE+ N+               TYISL+R+   T + DE LV
Sbjct:   65 FGEISSIRGVQNISRAETPFIRSLWILFVITMTSLLTIFSSFLIRDYLLYETNWHTRTLRDDKTAFPSITLCAHNPFSLEANRFWREGSTPNPKQINSRFTEIATEVLRQHNVAFSINLLLL-DSIETFYTNLDPKVRYNIGHKMEMFPHCMVTSESAHIVAEKCKLELDTELHLHRISHPKYFNCWTIEGKALEATKEITRLIMLVQLVPSKKINEANLSFIMDTFTRGEGVISVVHEPGTYPEIEKHGINIQPNRMNQIIYKPVLWNRLATPKAPCSEHPPPISDLGVNYTYTQGQCLNTVLQEQLLARCGCLNTEYPRPASTDFPVNPTPYCTSLNESLTNPEMASKLIERFQCIGEVMDRLKEIKEEAARQGRCPPRCSYFTYENRLSVTLWDPNAHNLAAYTERYRKLDGLLKAQSSMNMKTSFVSYWNASIQ----QFSSLDLESHNQPERFAEYSQFVDGSVTYISLTRQEFETTVMDERLV 548          

Query:  574 SHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCY--------TIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQS--PIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWEN---------TKCMQKCNYFTYNTELSITKW 1311
            S G E+++ C   SD      +              F H  + NC+        T+ Q SN   +    L +++S+     IP     FL  I     G  +++H+ N+YP + + G+ V+ G   ++  E  +  R   P   C    +  PI +L     YS   C+    Q K+IE CGC   L+P P  P EK  YC N                Q+FT       K +E          T C Q C    Y   +S++ W
Sbjct:  244 SSGDELIRSCLFSSDTCSATNFT------------TFFHPMYGNCFIFNWGENETVMQVSNPGVEY--GLKLVLSIDQDEYIP-----FLTTI----AGAVIMVHDQNTYPFLSDLGVFVKTGVETSVGIEVGQLQRQGAPYSDCTMDGTDLPITNLYNGTAYSVQACLRSCFQTKMIEMCGCGYYLYPLP--PGEK--YCQN----------------QNFTGWRYCYYKLYEQFVEEDMDCYTICKQPCIESEYKMSISMSDW 465          

Query:  682 FSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFN--YSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTE----LSITKW 1311
              H    NC+T    S+     I S  I   L    +  +  NS  +  L  G G K+ IH  N+ P IE  GID+ P   +++        +   P   C    S I D+K  ++  YS   C N   Q ++I++CGC N   P P    E   +C    +      +  L     + M +K      E  KC+Q C      TE    LS+  W
Sbjct:  269 LQHPILGNCFTFNDGSDGKSLDIASAGIDYGLHMVLNTRQ-DNS--LPYLAMGAGAKIGIHLQNTTPFIEAVGIDIPPAMESSLGLRVNDVQKLGDPYSDCTMDGSDI-DVKSLYDSPYSVQTCQNSCFQWEMIKSCGCANYEQPLP----EGSRFCNYDNNPGWEYCYYRL-----YDMYIK------EELKCIQVCRQICSETEHEVTLSLADW 465          

Query:  682 FSHQKFFNCYT--------IQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQS--PIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEK---------IGYCMNLTHRN--SSQIFTNLKCAQDFT 1212
            F H  + NCYT        + Q S   +    SLI+             +N ++   L    G ++++H+  S P +EE G D++PG   ++    ++  R   P   C    S  P+ +L     Y+         QL L+E CGC    +P P  PN            G+C    +R   S ++    KCAQ  T
Sbjct:  233 FHHPTYGNCYTFNSANSSKLWQASKPGRDYGLSLILRTE----------QNDYI-PFLSTVAGARIMVHDQESPPFMEEGGFDMRPGFETSLGIRMLEATRMPDPYGNCTEDGSNVPVLNLYSS-AYTVQVPECSCFQLALVEACGCGYYFYPLP--PNASYCSYNNTAWAGHCYYKLYRQFISDELGCVDKCAQPCT 416          

Query:  682 FSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPEL--KNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWAR-HSTPPQKCKN-----GQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
            F H K+ NC+       ++ +   +L  L +        EL  +    +D L    G  + +      P  EEEGIDV PG   +I    VK +R  +   + C N      +  ++ +K    YS + C+N+ L     +TC CM   FP   +  E +   MN          T ++C +     +K +KK     +C   CN  TY T  S + W
Sbjct:   56 FWHNKYGNCFVFNPLIGWNGKKRRALTALRAGPNYGLTLELNVEQDEYIDGLSTKAGAVIQVSPVGYMPFPEEEGIDVSPGFSTSIALTKVKISRVDAFGNRSCVNEITEKDRENLYHVKYNATYSKTACLNFCLAYNQRKTCNCMEYRFP---VEEEAVCDTMNK---------TTVECLRRVREMLK-MKKLNCTAECSAPCNQETYKTTSSFSMW 260          

Query:  223 WIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVN-TTKDPNE-------LTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMN----NIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQF--NYSFSFCMNYNLQLKLIETCGC 1092
            W+  V    +     + L I  + ++  +  + T++     FPA+T+C+ NP S                  + R  Q   +  N +T+D N        L   M    + +Y  +ID   SLK     E  KY               E  K+       F H ++ +C+T      +  + + S+  +  L    ++ E  +  + ++     G K+++H+P  +P IEE G  +QPG        +KY  +K       P + + G++ I D  R F  NY+ + C    L    I+ CGC
Sbjct:    1 WLFVVLAGFAGFIYQSFLSITSFYSWPVSTVMMTEWHKEMNFPAVTICNFNPIS------------------KSRYAQNYGNLFNLSTQDSNNIINGIIFLIGPMLGKSLRSYAHSIDGILSLKW---LEPCKYSGK------------ECGKNSFS---TFEHLRYGSCHTFNSDGQFGLK-VDSIGPISGLQLRLNVEEKDH--VSNLYGLQAGFKVLVHDPREHPMIEETGFALQPGTHTFCSVRMKYVNLK------APYRTECGEN-ITDFNRYFNVNYTMAICSKQCLHDYGIKKCGC 258          

Query:  142 FNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRT----KFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTK------------DPNELTL--MMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFS--HQKFFNCYTIQQTSNYSQQTI---TSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSF----CMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKW 1311
             N F + ++  G  ++        ++ W+  +FC+ +    V  L+    +N Y +  ++T    K     +FP +T+C+ N   LRA+ L        P   R +  Q+ I+  N T             DP +L+       + +     + DY   +  +H  E +     F+        NC   KD  +        +  F NCY       ++ + +   +S +   S      +   +N +L  I E   G+K+ I +    P   ++GI + PG+   I+   ++  R      +     + + D    F Y+ ++    C    L  + IE CGC N  +  P +    I  C    +R +S I   L  A D      T +    + +C   C+  +++  +S  +W
Sbjct:   15 INQFLQETTAHGFGRLGATAGSKWRLYWV--MFCLAAYCVFVWQLV--GLVNQYNSKPIKTRTQLKHAQKLDFPVVTICNMN--VLRASRL--------PPKLRTKFDQI-INNTNKTSPRNSSNSRNAFVDPQDLSFEETKKFEILHAVTAHDDYRELVSAAHQLEDILLSCNFNG------VNCRNSKDPTIPTYWTQTWNDNFGNCYMFNSVKTHNGEKVDLYSSSVPGESNGLTLQLNLEQNEYLEGITEVA-GMKVTISDQGVLPFPGQQGIRIMPGQSTGIQMTKLQTRRIDPFKNRSCESSNEMSDKNLFFGYNMTYSIMACKYSCLNARKIERCGCTN--YNTPEMQKRNIPLC----NRLNSTIIDCLNKAYD------TFEDGSCDRECPPSCSEVSFDLTVSSARW 397          

Query:  844 GLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQF--NYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCM-NLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELS 1299
            G K+++H+   YP +E+ G  +QPG       +  K+    T P   K G++ I D  R F  NYS S C    L    I+ CGC      +P  P     YC   +  +N+ +I   L  A+ F        K++    C   C+Y  Y T+LS
Sbjct:   49 GFKVLVHDRKEYPIMEQTGFALQPGTHTFCSTKLKKYKNLPT-PYNTKCGEN-ITDFNRYFSVNYSMSTCGKQCLHDYGIKKCGC------QPIYPITMKLYCQKRIVFKNAPKILIFLFAAECF--------KKY----CPVPCDYTKYETKLS 183          

Query:  136 NAFNLFCEISSIRGMHKITKAPTLFLKVLW-IAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNS-EFPAITLCSHNPF--SLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEML---KYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQ-TITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTP-PQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQD-FTMNVKTLKKQW--ENTKCMQKCNYFTYNTELSITKW-VPS-YEKL--FRIADLINKTEIYLKNHRERESKEDYISYIQANIT 1437
            N    F   +++ G H +  + + + + +W +  +FC    +F+   ++  + L  Y     R        +FPA+T+C+ N    SL  N+  +         F+  LKQ      N + D  E         ++ Y  NI           T ML   K C         + Y C  E         FS  + + CYT    +NY Q+ ++      + L   A   E    F  D    G G K+ +H+ N  P+++  G D+ PG +  I  +  K      P P KC  G   +   +R   YS               T GC    F + F+   K   C  L      +I     C     +  +    K W  E   C + C    YN +LS   +  PS  ++L  F +   +NK            SKE+Y+ +++ NI 
Sbjct:   25 NMIREFAGYTTLHGFHFLVDSSSRWRRRIWFLLLLFCCA--MFIYQFVISVNRLRAYKVVFSRGAEQPGEVDFPAVTICNKNMLRKSLILNTSAQIYLDEQDADFKRSLKQS-----NISFDAEEF--------VKKYGHNI-----------TNMLNRAKGCTF------KMLYPCSGENFTSF----FSFTRGW-CYTFNAGANYIQRVSVAGRETRLKLYLDAKSHEYYGPFSYD----GVGFKIAVHDQNDVPDMDNGGYDISPGYLTTISVKRFKEVSLPPPFPTKC--GSRTLEHYER---YS---------------TKGCEYECFAKDFVRKFK---CKTLGMAPIKEIRNASFCPVSVVSAALMDFHKNWHLELCDCPKPCETVNYNAQLSTAHYPAPSLLDELSKFPLEGFVNK------------SKEEYVKFVRDNIV 398          

Query:  103 KSESNVLVIDKNA-FNLFCEISSIRGM-HKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSE----FPAITLCSHNPFSL---------RANSLWKKPNAP----NPEMFRERLKQVVIDEVN-TTKDPNELTLMMFHDK----IENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTIT-------SLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPG-------KMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFP--RPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNH 1383
            K++S+ +   + A   +F   S++ G+ H  T       + LWI F      +L +V      D + +Y  +   TK D+ +     FPAIT C+ N F            A  L    N      +P +  E + QV+ +  +  +  P    +  F+D+    I++  ++  Y        GTE                  C  E  KV+        ++  CYT     +     +T        L +++ +     +P    +   D      G+K+ IH     P I++ G  V PG       +   + Y P  W    + P       S  F+     +YS + C        L+E C C     P   P+   E+   C +               A DF      +++  +   C   CN   Y  ELS  K +PS      +A   NKTE Y+ ++
Sbjct:    4 KADSDEMDYKRPAPIEVFATRSTLHGISHMFTYERMCLKRTLWILFFMLSVGVLVMVC----VDRVQFYFEYPHVTKLDEVAASMIVFPAITFCNLNSFRFSRVTRNDLYHAGELLALLNGRYEIRDPHLVEENVLQVLRERADFESYKPRSFNMREFYDRTGHDIKDMLLSCSY-------RGTE------------------CSAENFKVI------FTRYGKCYTFNSGKDGQPLMVTMKGGTGNGLELMLDIQQDEYLPVWGET---DETSFEAGIKVQIHTQEEPPFIDQLGFGVAPGFQTFVSCQEQRLTYLPPPWGDCKSTPM-----DSDFFN-----SYSITACRIDCETRYLVENCNCRMVHMPGDAPYCSPEQYKECADP--------------ALDF-----LVERDNDYCVCETPCNLTRYGKELSFVK-IPSKASAKYLAKKFNKTEQYIADN 402          

Query:   61 MISTEKETIKQASRKSESNVLVIDKNAFNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISYIQANITNSYINSSFLDLENENKFTYISLSRKTRNTVIKDEELV 1548
            MISTEKETIKQASRKSESNVLVIDKNAFNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISYIQANITNSYINSSFLDLENENKFTYISLSRKTRNTVIKDEELV
Sbjct:    1 MISTEKETIKQASRKSESNVLVIDKNAFNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISYIQANITNSYINSSFLDLENENKFTYISLSRKTRNTVIKDEELV 496          

Query: 1544 LLDLAILMSRIGGLCSLFIGLTVSFFIELVEFGYLICRKYSFQKGSLGAKRINNNKRQISELNNIIYEKSAANAFGKKSRQHCEEIIDFIKETESYDSLDHKPNVEWFRIGXXXXXXXXXXIPQVC 1921
            +LDLAILMSRIGGLCSLFIGLTVSFFIELVEFGYLICRKYSFQKGSLGAKRINNNKRQISELNNIIYEKSAANAFGKKSRQHCEEIIDFIKETESYDSLDHKPNVEWFRIGDPNNPNNDDPIPQVC
Sbjct:  496 VLDLAILMSRIGGLCSLFIGLTVSFFIELVEFGYLICRKYSFQKGSLGAKRINNNKRQISELNNIIYEKSAANAFGKKSRQHCEEIIDFIKETESYDSLDHKPNVEWFRIGDPNNPNNDDPIPQVC 621          

Query:  148 LFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQ-IFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISY-----------------IQANITNSYINSSFLDLENENKFTYISLSRKTRNTVIKDEELV 1548
            LFC+ISSIRG+ KI  A T F + LW  FV  MT +LF+    LI+DYL Y TAWH  T+ D  S FPAITLC+ NPFS+ AN LW K    +P   ++ L  + ++  +  K+ + L  +  +D    +YMN+ +  ++K+ H  +M++YC +     III   C+ + +K   K+ FSHQ++FNCYTI+    Y+   I  LI+LV + P+  IPEL NSFL+DIL+RGEGLK+ +H+P +YP+IE  GI++ P KMN++ Y P KW R ST    C++ Q PI DL R F Y+F+ C++  +Q ++I+ CGCM +  PRP+ PNE I YC+ L     ++ I   L C ++       ++K  +N  C  KC + TY T +S+T+W  +  KL  + +L      Y    R   S E+ +                   I  N  N+ IN S  D   EN FTYISL R+  +   K E+LV
Sbjct:    6 LFCQISSIRGISKIHSAKTKFERFLWTGFVILMTCVLFVQMVFLIQDYLQYTTAWHTSTELDYPSPFPAITLCAQNPFSIDANRLWSKRKIMSPSELQDNLTIMSLNAFDD-KNLDGLEYLRLYDLFSTFYMNLPFLDTIKLGHSKDMIRYCILIYKNDIIIAEKCDLKNEKFNIKL-FSHQEYFNCYTIEGLEQYTTDVI-GLILLVQIIPSEKIPELSNSFLVDILQRGEGLKVAVHQPQTYPDIENSGINMHPAKMNSLVYSPTKWIRMSTSKNPCRDKQKPINDLNRHFKYAFTQCVSAEIQRQIIKQCGCMLSNAPRPYPPNETIPYCIKLVSPTKAKLILERLSCVENIQSQSVEIRKTIQNDLCFLKCQFTTYETTMSLTRWTANELKLKNLENLYRSYFAY----RHNSSSENIVKIKSILLNSLNRSHNLRHQINKNQFNNLINYSRFD---ENAFTYISLMRRNFDIQWKTEKLV 480          

Query:   55 GKMISTEKETIKQASRKSESNVLVIDKNAFNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQTS-------NYSQQT--ITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCA-QDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYL------KNHRE--RESKEDYISYIQANI----TNSYINSSFLDLENENKFTYISLSRKTRNTVIKDEEL 1545
             KM S   E  KQ    +    L    + F +FCE SS+RGM KI K+ T FLK LWIAFVF M+ LL +++  L+ D+ NY+TAWHV T+ D+ + FPAI++CSHNPFS +A+  WK+     PE FRERL +V ++ + +   P +  L    DK E YY N+DY  S+K+ H  ++L+YC + +DG  II  +C  E +       FSH  +FNC+TI+  S       +Y  +T    SLI+L+++   +D+ +   SF+MD L RGEGL++VIH   SYP+I++ GI++QPGKMN + ++ + W R+S+P ++CK+ Q PI DL R ++Y+F+ C++  +  +L+E C CM+ ++PRP +P++ + YC + +  N + I    +C  ++    +K +K     TKC   C + TY++ LSIT+W PS  KL +I         Y+      KN+ E   + K +YI+ ++  +    T S+  S   ++ NE++  YI+L RK  +T  K E+L
Sbjct:   24 SKMHSFLTEDCKQFLSHNHDPNLKTPISKFAIFCEASSVRGMQKIHKSKTPFLKALWIAFVFFMSILLIIISTNLVIDFRNYHTAWHVSTELDEKTRFPAISICSHNPFSKQASRYWKEGKILPPEKFRERLFEVEMELIKSGNLPGQTLL----DKAEEYYGNVDYPSSIKLGHVRKILQYCVVQNDGFTIIAEDCLVENETGFTVSQFSHYNYFNCFTIEAKSEKNGLIKSYGDKTNETVSLILLINVNLFSDLFQANESFVMDSLTRGEGLRIVIHRVGSYPDIDKNGINIQPGKMNEVNFQNIHWTRYSSPKRECKDDQPPIVDLDRIYDYTFAQCLDAIVNKELVEKCQCMSTIWPRPQLPSKDVPYCNDYSG-NLTTIVKRTQCVYEEVFQKLKPIKAAAVGTKCWPLCTFNTYDSTLSITRWKPSLLKLRQITKRYRSVNKYIDDISLAKNNTETIEQLKSNYINELKRELKYKPTLSHHKSE--EIFNEHQMNYINLVRKNFDTTKKIEKL 535          

Query: 1538 KNLLDLAILMSRIGGLCSLFIGLTVSFFIELVEFGYL 1648
            K  +D+ I +SR+GGLCSL IGLT +FFIE++EF YL
Sbjct:  534 KLFIDIYIFISRVGGLCSLCIGLTTAFFIEIIEFVYL 570          

Query:  148 LFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKIVFSHQKFFNCYTIQQT----SNYSQQTITS-----LIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNLKCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIY-LKNHRERESKEDYISYIQ--ANITNSYINSSFLDLENENKFTYISLSRKTRNTVIKDEELV 1548
            LFCE  SIRGM KI +AP  FL+ +WI +V  MT+LL + +  L +D+ NY TAWH  T FD+ +EFPAI++CSHNPFS  AN +W++     P+ F E L  V I+ V   +   E+     +D  E YY NI+Y+ S+ +SH  E+L+YC + +D  + I   C+           FS+ K+FNC+TI++       +S   +++     +IIL+ +TP +D+ ++ +SF+MD L RG G+K+V+HE  + PEIE  GI++QPGKMN I +E + W R+++P + C N QS I DL   + Y+ S C+   LQ   I+ CGCMN+ +PRP  P++ I YC N +  ++ +I    +C+     +    K++  +TKC   C+YFTY+T++S+T W PS  KL R+      T+IY L N    E+ E     ++         I+ +   L +E++FTYI++ RK  +T+ K E LV
Sbjct:   88 LFCEAISIRGMQKIARAPNNFLRSVWIGYVILMTTLLTVTSYFLFRDFFNYNTAWHTSTAFDEKTEFPAISICSHNPFSENANRMWQENLVMTPKKFEELLTNVSINMVKNNRGGGEI----LYDSAEYYYGNIEYESSVNLSHKEEILRYCVLTTDAYVYIAEQCDLASYVAYRLRKFSNSKYFNCFTIEEDPEKLKTHSADVVSTRELLSIIILIQITPESDLTQINSSFVMDTLTRGTGVKVVLHEVGTSPEIENYGINLQPGKMNEISFETIHWNRYNSPKRPCLNNQSNIIDLGNSYKYTMSKCVEAELQKSTIKNCGCMNSNWPRPVKPSQNIPYCTNFSC-STDEILKRYECSS--IKDQGLTKQKLVDTKCFGVCSYFTYDTKVSVTNWKPSLYKLNRV------TQIYKLANENYTETDEGKTERVKKLKEKPQDTISKNLNMLTDESRFTYINVVRKNFDTIKKTERLV 553          

Query: 1544 LLDLAILMSRIGGLCSLFIGLTVSFFIELVEFGYLICRK 1660
            ++D +I MSR+GGLCSL +GLT + F EL+EF YL   K
Sbjct:  553 VIDASIFMSRVGGLCSLLVGLTTAVFAELIEFCYLAFHK 591          

Query:  133 KNAFNLFCEISSIRGMHKITKAPTLFLKVLWIAFVFCMTSLLFLVTGLLIKDYLNYYTAWHVRTKFDDNSEFPAITLCSHNPFSLRANSLWKKPNAPNPEMFRERLKQVVIDEVNTTKDPNELTLMMFHDKIENYYMNIDYDFSLKISHGTEMLKYCAIFSDGLIIITYNCETEKDKVVEKI-VFSHQKFFNCYTIQQTSNYSQQTITSLIILVSLTPAADIPELKNSFLMDILERGEGLKLVIHEPNSYPEIEEEGIDVQPGKMNNIKYEPVKWARHSTPPQKCKNGQSPIFDLKRQFNYSFSFCMNYNLQLKLIETCGCMNALFPRPFIPNEKIGYCMNLTHRNSSQIFTNL-----KCAQDFTMNVKTLKKQWENTKCMQKCNYFTYNTELSITKWVPSYEKLFRIADLINKTEIYLKNHRERESKEDYISYIQANITNS-----------YINSSFLDLENENKFTYISLSRKTRNTVIKDEELV 1548
            K+   LF +  SIRG+ KI  A + F K LWI+FV  MT +L L    L+K+YL Y T WH  TKF+D + FP IT C+ NPFS ++N +W +    +P   +++L  + ++ +    + + L+ +  +D    +YMN+  + S+K+ H  ++++YC I     I +  NC+    ++  KI +FSHQ FFNCYTI+    Y++ +I  LI ++ + P+ +I EL  SFL+D+L RG+G+K+VIHEP++ P+I+  G ++ P KMN+I Y    W R  TP   C + Q  ++DL R F Y+   CM    Q ++I  C CM +  PRPF+PN    YC+ L + N+S+I         K  + F++N + ++ Q+    C  +C Y TY T +S+T+W  S +KL  +  L  ++   LK  + +E+  + I+ +++++ ++            +N S +     N  TY+S++RK     IK E+LV
Sbjct:    9 KSKTKLFFQTFSIRGVSKIHHAKSQFEKTLWISFVIIMTFILILTMIFLVKNYLQYITTWHTSTKFEDQAAFPGITFCAQNPFSKKSNEIWMRNQILSPTQMQDKLTLLSLNALENLNN-SLLSYLRLYDLFSTFYMNLSPNESVKVGHSRDIIRYCIIMKGHDIDVAENCQDSISQL--KISLFSHQDFFNCYTIEGEQEYTK-SIVGLIFILDIVPSDEIYELSKSFLIDMLNRGDGMKIVIHEPHNLPDIDNSGFNLHPSKMNSIVYSQTDWYRLRTPKVNCHDNQPNLYDLGRSFKYTHKHCMESQFQTEVINKCQCMLSNHPRPFLPNSSFPYCLKLNYTNNSEILDKRFSCVEKVQEHFSLNREIIENQF----CSLRCRYSTYETTMSLTQWKASEQKLEHLQKLY-RSYFSLKQKQSKENINNVINILKSSLKDTKDFRENLRKFHKLNKSLVR-NKINDLTYVSITRKNFEISIKKEKLV 487          

Query: 1472 KTKINLLT*V--YRGKHEIP*SRMKNLLDLAILMSRIGGLCSLFIGLTVSFFIELVEFGYLICR 1657
            + KIN LT V   R   EI   + K +LD   L+SR+GGL SL IGLT +F  E++EF Y+IC+
Sbjct:  461 RNKINDLTYVSITRKNFEISIKKEKLVLDSNTLLSRMGGLSSLCIGLTAAFVAEIIEFIYIICK 524