Integrase catalytic domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30034308 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A5S6QJ61 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1) HSP 1 Score: 119.783 bits (299), Expect = 4.906e-83 Identity = 56/135 (41.48%), Postives = 86/135 (63.70%), Query Frame = 2 Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESL-ENAKVLGLRI 1774 +HT SDVC + L++W + G + ++DL YLQ+ + E+LW Y+ + + Y LTRL FGLN AP IM V++ VL +P ++ T Y+D+I+V+ V +V HLA+YGL+ K E + + A+VLGLR+ Sbjct: 477 THTADSDVCAQKLREWRRQGANVSVIDLNKAYLQIRIDESLWPYQTVVFKRRRYCLTRLGFGLNVAPLIMKAVVKCVLSQDPNVEKGTSAYIDDIMVNEDVVGAGQVEQHLARYGLSCKAHERVADGARVLGLRV 611 HSP 2 Score: 79.7221 bits (195), Expect = 4.906e-83 Identity = 53/145 (36.55%), Postives = 82/145 (56.55%), Query Frame = 1 Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGEN-HL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWL 2385 GR V+ + R+ W +ASS A+ V L G VEDA+WLR+ E H+ M +L KG++L + +N IE+M D S V W+ L+ + E L++RR+GI+ L + + + + LV+SA+N+AD LT +P W Sbjct: 701 GRWDVSGNEARV-WVDASSLAVGVALEVGGSIVEDAAWLRRDEACHINMA-ELDAVIKGLNLALSWQMNVIELMTDSSTVHRWISDGLSGRTRLKTKAASEMLIRRRIGIVLSLVEECGLNLNISLVRSADNKADALTRIPRSWF 843 HSP 3 Score: 62.003 bits (149), Expect = 4.906e-83 Identity = 26/86 (30.23%), Postives = 48/86 (55.81%), Query Frame = 3 Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKI 2711 H G+ +++YF + P ++ + + I P +KW HG L V + +G+D+ +++ +LT++DCGPSRFS+W + Sbjct: 874 HPGVRRTLYFARRVCPTVSKQQARQVVINCEACQSIDPAPVKWRHGRLNVEKVWQRLGMDITHFRGRPYLTLIDCGPSRFSIWRPL 959 HSP 4 Score: 50.8322 bits (120), Expect = 4.906e-83 Identity = 21/52 (40.38%), Postives = 32/52 (61.54%), Query Frame = 2 Query: 2741 NLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896 LE VF E G ELL DN+ +F+ + QL++ W+I+ ++CAY P+ G Sbjct: 970 QLETVFYEHGAPEELLTDNDTAFRSKAFAQLAARWDIRVRFRCAYVPSGNGM 1021 HSP 5 Score: 48.521 bits (114), Expect = 4.906e-83 Identity = 22/39 (56.41%), Postives = 26/39 (66.67%), Query Frame = 3 Query: 1818 IEKEITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934 + +TRRI S CGKLVGH PV LRVA ++ KR AN Sbjct: 629 VPDRLTRRIVFSYCGKLVGHLPVCGWLRVATAFAKRKAN 667 HSP 6 Score: 44.2838 bits (103), Expect = 4.906e-83 Identity = 30/102 (29.41%), Postives = 43/102 (42.16%), Query Frame = 1 Query: 2878 SSGNGILERNHWTIKFHADPR-----DIVFWYNAAPRDGINQDVGSSEGLFLYHWRFYRRVV-------------------VKPAPSKCTT*WPIGIVTGIL 3111 SGNG++ER H T+K A + + V+ YN PRD + G++ Y R R V VKPA +C + G VTG++ Sbjct: 1016 PSGNGMVERCHRTVKVIAARKGCSIEEAVYLYNITPRDDRTSQAAPANGVYKYAVRIRRVDVSSKEGPQESSPYAAGDAVWVKPAGIRCDRRYQTGTVTGVM 1117 HSP 7 Score: 39.2762 bits (90), Expect = 4.906e-83 Identity = 16/28 (57.14%), Postives = 21/28 (75.00%), Query Frame = 3 Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVE 1373 + L+ + NK KVRPV DFRELN+Y+E Sbjct: 449 VPLMAVVQRNKSKVRPVMDFRELNDYIE 476
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A5S6Q7P6 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1) HSP 1 Score: 127.102 bits (318), Expect = 5.225e-80 Identity = 65/139 (46.76%), Postives = 87/139 (62.59%), Query Frame = 2 Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLEN-AKVLGLRIKRDR 1786 ++T +SDVC E L++W Q G + ILDLK YLQ+ V ++LW Y+ + Y LTRL FGLN AP IM V+ +VL L P I T Y+D+I+VD + V + V HLAQYGL K E + N A+VLGL + +R Sbjct: 174 TYTARSDVCAEKLREWRQRGANIAILDLKKAYLQVRVEKSLWPYQTVMLRGRRYCLTRLGFGLNVAPTIMKAVVDRVLSLVPNISKGTSAYLDDILVDETVVSAHAVKRHLAQYGLECKSPEKVSNGARVLGLAVWGER 312 HSP 2 Score: 78.1814 bits (191), Expect = 5.225e-80 Identity = 54/162 (33.33%), Postives = 83/162 (51.23%), Query Frame = 1 Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGENHL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWLKLWNSFGCSKLSTEKIKE 2439 GR V++ +I W +AS AL V L +G +ED +WLR E +L KG++L I + +IE+M D + V W++ L+ + E L++RRL + L + + + + LV+S+EN+AD LT VP +WL S E IKE Sbjct: 398 GRWDVSSKRAKI-WVDASMLALGVALEVDGSVIEDGAWLRPEEARHINMAELDAVIKGLNLAIAWRMKQIELMTDSATVHRWIEDALSGRARLRTKATNEMLIRRRLETVLALVKEYDLAVTITLVRSSENKADCLTRVPSRWLS----------SVEPIKE 548 HSP 3 Score: 66.2402 bits (160), Expect = 5.225e-80 Identity = 27/87 (31.03%), Postives = 48/87 (55.17%), Query Frame = 3 Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKID 2714 H G+ +++YF + +P + + + I P +KW HG+L V + +GID+ + +L++ DCGPSRFS+W ++D Sbjct: 572 HPGVRRTLYFCRRRDPRISKREVSRVVGTCDVCRSIDPAPVKWRHGVLEVPSIWQRVGIDVVHCGSELYLSLTDCGPSRFSIWRRLD 658 HSP 4 Score: 47.3654 bits (111), Expect = 5.225e-80 Identity = 19/52 (36.54%), Postives = 31/52 (59.62%), Query Frame = 2 Query: 2741 NLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896 +LE +F ERG ELL DN+ +F+ + +L+ W + ++CAY P+ G Sbjct: 668 HLESIFLERGAPDELLADNDTAFRSREVARLAEKWGTRIRFRCAYVPSGNGI 719 HSP 5 Score: 43.8986 bits (102), Expect = 5.225e-80 Identity = 18/37 (48.65%), Postives = 27/37 (72.97%), Query Frame = 3 Query: 1824 KEITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934 + +T+R S CG+L+GHYPV LRVA +++KR +N Sbjct: 328 RRLTKRSVFSYCGELIGHYPVGNWLRVATAFVKRESN 364 HSP 6 Score: 36.5798 bits (83), Expect = 5.225e-80 Identity = 15/33 (45.45%), Postives = 22/33 (66.67%), Query Frame = 3 Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVEVTPVR 1388 + L+ + +K+KVRPV DFRELN Y++ R Sbjct: 146 IPLMAVVQRSKKKVRPVLDFRELNTYIDTYTAR 178 HSP 7 Score: 34.6538 bits (78), Expect = 5.225e-80 Identity = 29/102 (28.43%), Postives = 39/102 (38.24%), Query Frame = 1 Query: 2878 SSGNGILERNHWTIKFHA-----DPRDIVFWYNAAPRDGINQDVGSSEGLFLYHWRFYRRVV-------------------VKPAPSKCTT*WPIGIVTGIL 3111 SGNGI ER H T+K A R+ V+ YN PRD + ++ Y R V VK +C + G+VTG+L Sbjct: 714 PSGNGIAERCHRTVKVIAARTGCSIREAVYRYNLMPRDDHTSATAPANVIYRYTVRDKNEAVTSSSEQSTNGPYVVGEPVWVKSRGGRCDDRYERGMVTGLL 815
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A5S6QF31 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1) HSP 1 Score: 127.102 bits (318), Expect = 6.883e-80 Identity = 65/139 (46.76%), Postives = 87/139 (62.59%), Query Frame = 2 Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLEN-AKVLGLRIKRDR 1786 ++T +SDVC E L++W Q G + ILDLK YLQ+ V ++LW Y+ + Y LTRL FGLN AP IM V+ +VL L P I T Y+D+I+VD + V + V HLAQYGL K E + N A+VLGL + +R Sbjct: 174 TYTARSDVCAEKLREWRQRGANIAILDLKKAYLQVRVEKSLWPYQTVMLRGRRYCLTRLGFGLNVAPTIMKAVVDRVLSLVPNISKGTSAYLDDILVDETVVSAHAVKRHLAQYGLECKSPEKVSNGARVLGLAVWGER 312 HSP 2 Score: 78.1814 bits (191), Expect = 6.883e-80 Identity = 54/162 (33.33%), Postives = 83/162 (51.23%), Query Frame = 1 Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGENHL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWLKLWNSFGCSKLSTEKIKE 2439 GR V++ +I W +AS AL V L +G +ED +WLR E +L KG++L I + +IE+M D + V W++ L+ + E L++RRL + L + + + + LV+S+EN+AD LT VP +WL S E IKE Sbjct: 398 GRWDVSSKRAKI-WVDASMLALGVALEVDGSVIEDGAWLRPEEARHINMAELDAVIKGLNLAIAWRMKQIELMTDSATVHRWIEDALSGRARLRTKATNEMLIRRRLETVLALVKEYDLAVTITLVRSSENKADCLTRVPSRWLS----------SVEPIKE 548 HSP 3 Score: 66.6254 bits (161), Expect = 6.883e-80 Identity = 27/87 (31.03%), Postives = 48/87 (55.17%), Query Frame = 3 Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKID 2714 H G+ +++YF + +P + + + I P +KW HG+L V + +GID+ + +L++ DCGPSRFS+W ++D Sbjct: 572 HPGVRRTLYFCRRRDPRISKREVSRVVGTCDVCRSIDPAPVKWRHGVLEVPSIWQRVGIDVVHCGSEMYLSLTDCGPSRFSIWRRLD 658 HSP 4 Score: 46.9802 bits (110), Expect = 6.883e-80 Identity = 19/52 (36.54%), Postives = 31/52 (59.62%), Query Frame = 2 Query: 2741 NLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896 +LE +F ERG ELL DN+ +F+ + +L+ W + ++CAY P+ G Sbjct: 668 HLESIFLERGAPDELLADNDTAFRSREVARLAEKWGTRIRFRCAYVPSGNGI 719 HSP 5 Score: 43.8986 bits (102), Expect = 6.883e-80 Identity = 18/37 (48.65%), Postives = 27/37 (72.97%), Query Frame = 3 Query: 1824 KEITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934 + +T+R S CG+L+GHYPV LRVA +++KR +N Sbjct: 328 RRLTKRSVFSYCGELIGHYPVGNWLRVATAFVKRESN 364 HSP 6 Score: 36.5798 bits (83), Expect = 6.883e-80 Identity = 14/28 (50.00%), Postives = 21/28 (75.00%), Query Frame = 3 Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVE 1373 + L+ + +K+KVRPV DFRELN Y++ Sbjct: 146 IPLMAVVQRSKKKVRPVLDFRELNTYID 173 HSP 7 Score: 34.6538 bits (78), Expect = 6.883e-80 Identity = 29/102 (28.43%), Postives = 39/102 (38.24%), Query Frame = 1 Query: 2878 SSGNGILERNHWTIKFHA-----DPRDIVFWYNAAPRDGINQDVGSSEGLFLYHWRFYRRVV-------------------VKPAPSKCTT*WPIGIVTGIL 3111 SGNGI ER H T+K A R+ V+ YN PRD + ++ Y R V VK +C + G+VTG+L Sbjct: 714 PSGNGIAERCHRTVKVIAARTGCSIREAVYRYNLMPRDDHTSATAPANVIYRYTVRDKNEAVTSSSEQSTNGPYVVGEPVWVKSRGGRCDDRYERGMVTGLL 815
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A5S6QHX4 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1) HSP 1 Score: 126.716 bits (317), Expect = 6.883e-80 Identity = 65/139 (46.76%), Postives = 87/139 (62.59%), Query Frame = 2 Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLEN-AKVLGLRIKRDR 1786 ++T +SDVC E L++W Q G + ILDLK YLQ+ V ++LW Y+ + Y LTRL FGLN AP IM V+ +VL L P I T Y+D+I+VD + V + V HLAQYGL K E + N A+VLGL + +R Sbjct: 174 TYTARSDVCAEKLREWRQRGANIAILDLKKAYLQVRVEKSLWPYQTVMLRGRRYCLTRLGFGLNVAPTIMKAVVDRVLSLVPNISKGTSAYLDDILVDETVVSAHAVKRHLAQYGLECKSPEKVSNGARVLGLAVWGER 312 HSP 2 Score: 78.1814 bits (191), Expect = 6.883e-80 Identity = 54/162 (33.33%), Postives = 83/162 (51.23%), Query Frame = 1 Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGENHL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWLKLWNSFGCSKLSTEKIKE 2439 GR V++ +I W +AS AL V L +G +ED +WLR E +L KG++L I + +IE+M D + V W++ L+ + E L++RRL + L + + + + LV+S+EN+AD LT VP +WL S E IKE Sbjct: 398 GRWDVSSKRAKI-WVDASMLALGVALEVDGSVIEDGAWLRPEEARHINMAELDAVIKGLNLAIAWRMKQIELMTDSATVHRWIEDALSGRARLRTKATNEMLIRRRLETVLALVKEYDLAVTITLVRSSENKADCLTRVPSRWLS----------SVEPIKE 548 HSP 3 Score: 66.2402 bits (160), Expect = 6.883e-80 Identity = 27/87 (31.03%), Postives = 48/87 (55.17%), Query Frame = 3 Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKID 2714 H G+ +++YF + +P + + + I P +KW HG+L V + +GID+ + +L++ DCGPSRFS+W ++D Sbjct: 572 HPGVRRTLYFCRRRDPRISKREVSRVVGTCDVCRSIDPAPVKWRHGVLEVPSIWQRVGIDVVHCGSELYLSLTDCGPSRFSIWRRLD 658 HSP 4 Score: 47.3654 bits (111), Expect = 6.883e-80 Identity = 19/52 (36.54%), Postives = 31/52 (59.62%), Query Frame = 2 Query: 2741 NLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896 +LE +F ERG ELL DN+ +F+ + +L+ W + ++CAY P+ G Sbjct: 668 HLESIFLERGAPDELLADNDTAFRSREVARLAEKWGTRIRFRCAYVPSGNGI 719 HSP 5 Score: 43.8986 bits (102), Expect = 6.883e-80 Identity = 18/37 (48.65%), Postives = 27/37 (72.97%), Query Frame = 3 Query: 1824 KEITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934 + +T+R S CG+L+GHYPV LRVA +++KR +N Sbjct: 328 RRLTKRSVFSYCGELIGHYPVGNWLRVATAFVKRESN 364 HSP 6 Score: 36.5798 bits (83), Expect = 6.883e-80 Identity = 15/33 (45.45%), Postives = 22/33 (66.67%), Query Frame = 3 Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVEVTPVR 1388 + L+ + +K+KVRPV DFRELN Y++ R Sbjct: 146 IPLMAVVQRSKKKVRPVLDFRELNTYIDTYTAR 178 HSP 7 Score: 34.6538 bits (78), Expect = 6.883e-80 Identity = 29/102 (28.43%), Postives = 39/102 (38.24%), Query Frame = 1 Query: 2878 SSGNGILERNHWTIKFHA-----DPRDIVFWYNAAPRDGINQDVGSSEGLFLYHWRFYRRVV-------------------VKPAPSKCTT*WPIGIVTGIL 3111 SGNGI ER H T+K A R+ V+ YN PRD + ++ Y R V VK +C + G+VTG+L Sbjct: 714 PSGNGIAERCHRTVKVIAARTGCSIREAVYRYNLMPRDDHTSATAPANVIYRYTVRDKNEAVTSSSEQSTNGPYVVGEPVWVKSRGGRCDDRYERGMVTGLL 815
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A0V1H8A0 (Gag-Pro-Pol polyprotein OS=Trichinella zimbabwensis OX=268475 GN=T11_8379 PE=4 SV=1) HSP 1 Score: 124.02 bits (310), Expect = 2.249e-77 Identity = 64/153 (41.83%), Postives = 96/153 (62.75%), Query Frame = 2 Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSE-SLENAKVLGLRIKRDRFCHLLSIRGNDRKG 1828 SHT +DVC + L++W + G + ++DLK YLQ+ + ++LW Y+ + K Y LTRL FGLN AP +M VL VL +P ++ T Y+D+I+V+ S V V++V HLA YGLT K E + + A++LGL++ +R L+ R ND G Sbjct: 317 SHTADADVCSQKLREWRRQGVNVALIDLKKAYLQIRIDKSLWPYQTVVFKGKRYCLTRLGFGLNVAPLVMKAVLNCVLSRDPDVRKGTSAYIDDILVNESVVAVDRVKRHLAHYGLTCKTHERAADGARLLGLKVWGERG-KLMWRRDNDVGG 468 HSP 2 Score: 74.7146 bits (182), Expect = 2.249e-77 Identity = 52/145 (35.86%), Postives = 79/145 (54.48%), Query Frame = 1 Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGENHL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWLK 2388 GR V+ +I W +ASS A+ V L G VEDA+WLR + +L KG++L + + RI +M D + V W+ L+ ++ + E L++RR+ +I L + + + V LVKSA N+AD LT VP +WLK Sbjct: 541 GRWDVSAEEAKI-WVDASSLAIGVALEVGGSIVEDAAWLRPDDAQHINMAELDTVIKGLNLALSWQMRRIRLMTDSATVHRWVSDGLSGKARLKTKASGEMLIRRRVSMILSLVEEFGLELEVDLVKSACNKADELTRVPRRWLK 684 HSP 3 Score: 58.5362 bits (140), Expect = 2.249e-77 Identity = 24/86 (27.91%), Postives = 46/86 (53.49%), Query Frame = 3 Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKI 2711 H G+ +++YF + +P + ++ + + P KW G L V +G+D+ + + +LT++DCGPSRF+VW ++ Sbjct: 715 HPGIRRTLYFARRTDPTVSKRQVRQVITGCEPCKSLDPAPGKWKRGSLEVEEVWRRVGMDITHVRGRPYLTLIDCGPSRFAVWRRL 800 HSP 4 Score: 49.2914 bits (116), Expect = 2.249e-77 Identity = 21/57 (36.84%), Postives = 31/57 (54.39%), Query Frame = 2 Query: 2726 SNTERNLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896 +N LE VF ERG ELL DN+ +F+ + + W ++ Y+CAY P+ G Sbjct: 806 ANVTEQLEAVFCERGAPEELLTDNDTAFRGRIFTEFIARWGVRVRYRCAYVPSGNGI 862 HSP 5 Score: 46.595 bits (109), Expect = 2.249e-77 Identity = 21/35 (60.00%), Postives = 25/35 (71.43%), Query Frame = 3 Query: 1830 ITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934 +TRR S CGKLV H+PV LR+A +YIKR AN Sbjct: 473 LTRRSVFSYCGKLVSHFPVCGWLRIAAAYIKRKAN 507 HSP 6 Score: 37.7354 bits (86), Expect = 2.249e-77 Identity = 19/61 (31.15%), Postives = 35/61 (57.38%), Query Frame = 1 Query: 1210 RQDYEKEVKRWIKEDLLIPANDADH----GILPLLQQGKKTKGKFVRFLISESLIITLKSH 1380 R YE E+++WIK+ L+P ++++H G+LPL+ ++ K K + L ++SH Sbjct: 258 RGAYEDELRKWIKDGWLVPYDESEHGPPKGLLPLMAVIQRNKKKVRPVMDFRELNAHIESH 318 HSP 7 Score: 34.6538 bits (78), Expect = 2.249e-77 Identity = 30/102 (29.41%), Postives = 42/102 (41.18%), Query Frame = 1 Query: 2878 SSGNGILERNHWTIKFHADPR-----DIVFWYNAAPRDGINQDVGSSEGLFLY-----------------HWRFY--RRVVVKPAPSKCTT*WPIGIVTGIL 3111 SGNGI ER H ++K A + + V+ YN PRDG N + + Y RF V V+P ++C T G VTG++ Sbjct: 857 PSGNGIAERCHRSVKVIAARKNCTVEEAVYLYNVTPRDGRNPWTAPANVVHAYVVRVRGVDRATEEPEEKDGRFAVGDSVWVRPPGARCDTRHQKGTVTGVV 958
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000054470.1 (SMESG000054470.1) HSP 1 Score: 192.2 bits (487), Expect = 1.212e-53 Identity = 101/160 (63.12%), Postives = 115/160 (71.88%), Query Frame = 2 Query: 1382 GKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLENAKVLGLRIKRDRFCHLLSIRGNDRKGNHSSYTAFFMR 1861 G SDVC ESLK GDQ+V+LDLKN ++QLHV EN KY+K RY DK YYLTRLRF LNCA K+MS VLRKVL LNPRIKD+TDHY+D I VDTSKVQV +V N LAQ GLTTK ++S+EN K+LG RIKRD C I N YT +MR Sbjct: 87 GDSDVCGESLKNEDNGGDQVVMLDLKNAFVQLHVRENHLKYQKSRYKDKFYYLTRLRFELNCASKVMSLVLRKVLNLNPRIKDSTDHYIDGIAVDTSKVQVTEVGNRLAQIGLTTKPTDSIENTKILGFRIKRD-CCGSEEIIPVKSTANKLPYTVLYMR 245
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000054470.1 (SMESG000054470.1) HSP 1 Score: 190.66 bits (483), Expect = 8.628e-53 Identity = 101/160 (63.12%), Postives = 115/160 (71.88%), Query Frame = 2 Query: 1382 GKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLENAKVLGLRIKRDRFCHLLSIRGNDRKGNHSSYTAFFMR 1861 G SDVC ESLK GDQ+V+LDLKN ++QLHV EN KY+K RY DK YYLTRLRF LNCA K+MS VLRKVL LNPRIKD+TDHY+D I VDTSKVQV +V N LAQ GLTTK ++S+EN K+LG RIKRD C I N YT +MR Sbjct: 118 GDSDVCGESLKNEDNGGDQVVMLDLKNAFVQLHVRENHLKYQKSRYKDKFYYLTRLRFELNCASKVMSLVLRKVLNLNPRIKDSTDHYIDGIAVDTSKVQVTEVGNRLAQIGLTTKPTDSIENTKILGFRIKRD-CCGSEEIIPVKSTANKLPYTVLYMR 276
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000054470.1 (SMESG000054470.1) HSP 1 Score: 190.66 bits (483), Expect = 9.750e-53 Identity = 101/160 (63.12%), Postives = 115/160 (71.88%), Query Frame = 2 Query: 1382 GKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLENAKVLGLRIKRDRFCHLLSIRGNDRKGNHSSYTAFFMR 1861 G SDVC ESLK GDQ+V+LDLKN ++QLHV EN KY+K RY DK YYLTRLRF LNCA K+MS VLRKVL LNPRIKD+TDHY+D I VDTSKVQV +V N LAQ GLTTK ++S+EN K+LG RIKRD C I N YT +MR Sbjct: 124 GDSDVCGESLKNEDNGGDQVVMLDLKNAFVQLHVRENHLKYQKSRYKDKFYYLTRLRFELNCASKVMSLVLRKVLNLNPRIKDSTDHYIDGIAVDTSKVQVTEVGNRLAQIGLTTKPTDSIENTKILGFRIKRD-CCGSEEIIPVKSTANKLPYTVLYMR 282
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000013825.1 (SMESG000013825.1) HSP 1 Score: 102.064 bits (253), Expect = 1.931e-51 Identity = 51/136 (37.50%), Postives = 84/136 (61.76%), Query Frame = 2 Query: 1376 HTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSE---SLENAKVLGLRI 1774 ++ ++ VC+E++++W G+++ LDL + Y+Q+ V E++WKY+ N+K Y LTRL FG+N A IM+ ++ VL LN RIK Y+D+I +D V KV L+++ L TK E S + ++LGL + Sbjct: 372 YSDEAVVCNETIREWRNKGNKIATLDLSDAYMQIRVDESMWKYQSCIINEKRYALTRLGFGINIALGIMTEIVNHVLGLNDRIKQEASAYIDDIFIDEEVVPAEKVKAWLSKFNLMTKEIERPTSTKALRILGLSV 507 HSP 2 Score: 57.3806 bits (137), Expect = 1.931e-51 Identity = 32/116 (27.59%), Postives = 57/116 (49.14%), Query Frame = 3 Query: 2451 HHFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKIDREDAQTLKEIWRKYFEKEAQYQNYLWIM 2798 + FG ++ + I+ +K + K E I P S+K G L V + + + ID+ + FLT++DCGPSRF++W +I + A + + + F + N+ WI+ Sbjct: 736 YDFGGDRLKFLIEKSGINLSLNELKEIIEKCDECQSIDPHSVKISKGQLEVKDSWKRLAIDVTKLHQKRFLTIIDCGPSRFAIWREIRNKCADKICKQLEQAFYERGLLMNFCWII 851 HSP 3 Score: 56.225 bits (134), Expect = 1.931e-51 Identity = 42/123 (34.15%), Postives = 68/123 (55.28%), Query Frame = 1 Query: 2011 SFALEVVLITNGDAVEDASWLRKGEN----HL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLT 2364 S + L +G+ +EDA WLRK ++ +L ++ ++ KGI+L I+ + +++M D V SW+ L +E + E LVKRRL IIKEL + I + V + +N++DVLT Sbjct: 583 SIVIGAALEIDGNIMEDACWLRKKKDVKHINLCEFKAIV---KGINLCIKWNLKFVKIMSDNKSVVSWVHNALTSERKITTKASSEMLVKRRLSIIKELITEYEIKPKIEYVPTNKNKSDVLT 702 HSP 4 Score: 35.4242 bits (80), Expect = 1.931e-51 Identity = 14/29 (48.28%), Postives = 21/29 (72.41%), Query Frame = 3 Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVEV 1376 + L ++NK K+RPVFD R LN+Y++V Sbjct: 343 VTLFPVMQKNKSKIRPVFDLRALNHYLDV 371 HSP 5 Score: 34.6538 bits (78), Expect = 1.931e-51 Identity = 19/40 (47.50%), Postives = 24/40 (60.00%), Query Frame = 3 Query: 1821 EKEITRRIPL-SLCGKLVGHYPVAA*LRVAYSYIKRIANG 1937 E+ I R L SLC +L G P A LR A SY+KR++ G Sbjct: 527 EENIMNRQELYSLCSQLTGILPSAGWLRPACSYLKRLSEG 566
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000018147.1 (SMESG000018147.1) HSP 1 Score: 166.392 bits (420), Expect = 1.504e-47 Identity = 91/116 (78.45%), Postives = 93/116 (80.17%), Query Frame = 1 Query: 4357 NFKLSLEKDIVGLTLDGAVVNKKFIRHAEIIEQLCLNHGLHLGVSETLYKKKNLERDVGDASLVDTDYGSETDGFDENADIEFIEEDYSDGETDYKELLLKSRKLAKFIKLSSVKN 4704 NFKLS EKDIVG T DGA VNKKFIR AEII QLCLNH +HLGV ETLYKK NLERDV DASL DTD SE FDEN DIEFIEEDYS ETDYKELLLKSRKL K IK S+KN Sbjct: 3 NFKLSPEKDIVGSTFDGAAVNKKFIRPAEIIGQLCLNHVIHLGVCETLYKK-NLERDVCDASLFDTDDASERGEFDENTDIEFIEEDYSYEETDYKELLLKSRKLVKLIKRYSLKN 117 The following BLAST results are available for this feature:
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034308 ID=SMED30034308|Name=Integrase catalytic domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5929bpback to top protein sequence of SMED30034308-orf-1 >SMED30034308-orf-1 ID=SMED30034308-orf-1|Name=SMED30034308-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=100bp MMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIback to top protein sequence of SMED30034308-orf-2 >SMED30034308-orf-2 ID=SMED30034308-orf-2|Name=SMED30034308-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=146bp MGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKback to top Annotated Terms
The following terms have been associated with this transcript:
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