Integrase catalytic domain-containing protein

Overview
NameIntegrase catalytic domain-containing protein
Smed IDSMED30034308
Length (bp)5929
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Integrase catalytic domain-containing protein (SMED30034308) t-SNE clustered cells

Violin plots show distribution of expression levels for Integrase catalytic domain-containing protein (SMED30034308) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Integrase catalytic domain-containing protein (SMED30034308) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Integrase catalytic domain-containing protein (SMED30034308) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30034308

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30034308 dd_Smed_v4_12778_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30034308 dd_Smed_v4_12778_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30034308 dd_Smed_v4_12778_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30034308 dd_Smed_v4_12778_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30034308 dd_Smed_v4_12778_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30034308 dd_Smed_v4_12778_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30034308 dd_Smed_v4_12778_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30034308 dd_Smed_v4_35674_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A5S6QJ61 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 4.906e-83
Identity = 56/135 (41.48%), Postives = 86/135 (63.70%), Query Frame = 2
Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESL-ENAKVLGLRI 1774
            +HT  SDVC + L++W + G  + ++DL   YLQ+ + E+LW Y+   +  + Y LTRL FGLN AP IM  V++ VL  +P ++  T  Y+D+I+V+   V   +V  HLA+YGL+ K  E + + A+VLGLR+
Sbjct:  477 THTADSDVCAQKLREWRRQGANVSVIDLNKAYLQIRIDESLWPYQTVVFKRRRYCLTRLGFGLNVAPLIMKAVVKCVLSQDPNVEKGTSAYIDDIMVNEDVVGAGQVEQHLARYGLSCKAHERVADGARVLGLRV 611          

HSP 2 Score: 79.7221 bits (195), Expect = 4.906e-83
Identity = 53/145 (36.55%), Postives = 82/145 (56.55%), Query Frame = 1
Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGEN-HL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWL 2385
            GR  V+ +  R+ W +ASS A+ V L   G  VEDA+WLR+ E  H+ M  +L    KG++L +   +N IE+M D S V  W+   L+  +        E L++RR+GI+  L  +  + + + LV+SA+N+AD LT +P  W 
Sbjct:  701 GRWDVSGNEARV-WVDASSLAVGVALEVGGSIVEDAAWLRRDEACHINMA-ELDAVIKGLNLALSWQMNVIELMTDSSTVHRWISDGLSGRTRLKTKAASEMLIRRRIGIVLSLVEECGLNLNISLVRSADNKADALTRIPRSWF 843          

HSP 3 Score: 62.003 bits (149), Expect = 4.906e-83
Identity = 26/86 (30.23%), Postives = 48/86 (55.81%), Query Frame = 3
Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKI 2711
            H G+ +++YF +   P   ++  +  +        I P  +KW HG L V    + +G+D+ +++   +LT++DCGPSRFS+W  +
Sbjct:  874 HPGVRRTLYFARRVCPTVSKQQARQVVINCEACQSIDPAPVKWRHGRLNVEKVWQRLGMDITHFRGRPYLTLIDCGPSRFSIWRPL 959          

HSP 4 Score: 50.8322 bits (120), Expect = 4.906e-83
Identity = 21/52 (40.38%), Postives = 32/52 (61.54%), Query Frame = 2
Query: 2741 NLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896
             LE VF E G   ELL DN+ +F+  +  QL++ W+I+  ++CAY P+  G 
Sbjct:  970 QLETVFYEHGAPEELLTDNDTAFRSKAFAQLAARWDIRVRFRCAYVPSGNGM 1021          

HSP 5 Score: 48.521 bits (114), Expect = 4.906e-83
Identity = 22/39 (56.41%), Postives = 26/39 (66.67%), Query Frame = 3
Query: 1818 IEKEITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934
            +   +TRRI  S CGKLVGH PV   LRVA ++ KR AN
Sbjct:  629 VPDRLTRRIVFSYCGKLVGHLPVCGWLRVATAFAKRKAN 667          

HSP 6 Score: 44.2838 bits (103), Expect = 4.906e-83
Identity = 30/102 (29.41%), Postives = 43/102 (42.16%), Query Frame = 1
Query: 2878 SSGNGILERNHWTIKFHADPR-----DIVFWYNAAPRDGINQDVGSSEGLFLYHWRFYRRVV-------------------VKPAPSKCTT*WPIGIVTGIL 3111
             SGNG++ER H T+K  A  +     + V+ YN  PRD        + G++ Y  R  R  V                   VKPA  +C   +  G VTG++
Sbjct: 1016 PSGNGMVERCHRTVKVIAARKGCSIEEAVYLYNITPRDDRTSQAAPANGVYKYAVRIRRVDVSSKEGPQESSPYAAGDAVWVKPAGIRCDRRYQTGTVTGVM 1117          

HSP 7 Score: 39.2762 bits (90), Expect = 4.906e-83
Identity = 16/28 (57.14%), Postives = 21/28 (75.00%), Query Frame = 3
Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVE 1373
            + L+   + NK KVRPV DFRELN+Y+E
Sbjct:  449 VPLMAVVQRNKSKVRPVMDFRELNDYIE 476          
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A5S6Q7P6 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 5.225e-80
Identity = 65/139 (46.76%), Postives = 87/139 (62.59%), Query Frame = 2
Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLEN-AKVLGLRIKRDR 1786
            ++T +SDVC E L++W Q G  + ILDLK  YLQ+ V ++LW Y+      + Y LTRL FGLN AP IM  V+ +VL L P I   T  Y+D+I+VD + V  + V  HLAQYGL  K  E + N A+VLGL +  +R
Sbjct:  174 TYTARSDVCAEKLREWRQRGANIAILDLKKAYLQVRVEKSLWPYQTVMLRGRRYCLTRLGFGLNVAPTIMKAVVDRVLSLVPNISKGTSAYLDDILVDETVVSAHAVKRHLAQYGLECKSPEKVSNGARVLGLAVWGER 312          

HSP 2 Score: 78.1814 bits (191), Expect = 5.225e-80
Identity = 54/162 (33.33%), Postives = 83/162 (51.23%), Query Frame = 1
Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGENHL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWLKLWNSFGCSKLSTEKIKE 2439
            GR  V++   +I W +AS  AL V L  +G  +ED +WLR  E       +L    KG++L I   + +IE+M D + V  W++  L+  +        E L++RRL  +  L  +  + + + LV+S+EN+AD LT VP +WL           S E IKE
Sbjct:  398 GRWDVSSKRAKI-WVDASMLALGVALEVDGSVIEDGAWLRPEEARHINMAELDAVIKGLNLAIAWRMKQIELMTDSATVHRWIEDALSGRARLRTKATNEMLIRRRLETVLALVKEYDLAVTITLVRSSENKADCLTRVPSRWLS----------SVEPIKE 548          

HSP 3 Score: 66.2402 bits (160), Expect = 5.225e-80
Identity = 27/87 (31.03%), Postives = 48/87 (55.17%), Query Frame = 3
Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKID 2714
            H G+ +++YF +  +P   +  +   +        I P  +KW HG+L V    + +GID+ +     +L++ DCGPSRFS+W ++D
Sbjct:  572 HPGVRRTLYFCRRRDPRISKREVSRVVGTCDVCRSIDPAPVKWRHGVLEVPSIWQRVGIDVVHCGSELYLSLTDCGPSRFSIWRRLD 658          

HSP 4 Score: 47.3654 bits (111), Expect = 5.225e-80
Identity = 19/52 (36.54%), Postives = 31/52 (59.62%), Query Frame = 2
Query: 2741 NLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896
            +LE +F ERG   ELL DN+ +F+   + +L+  W  +  ++CAY P+  G 
Sbjct:  668 HLESIFLERGAPDELLADNDTAFRSREVARLAEKWGTRIRFRCAYVPSGNGI 719          

HSP 5 Score: 43.8986 bits (102), Expect = 5.225e-80
Identity = 18/37 (48.65%), Postives = 27/37 (72.97%), Query Frame = 3
Query: 1824 KEITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934
            + +T+R   S CG+L+GHYPV   LRVA +++KR +N
Sbjct:  328 RRLTKRSVFSYCGELIGHYPVGNWLRVATAFVKRESN 364          

HSP 6 Score: 36.5798 bits (83), Expect = 5.225e-80
Identity = 15/33 (45.45%), Postives = 22/33 (66.67%), Query Frame = 3
Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVEVTPVR 1388
            + L+   + +K+KVRPV DFRELN Y++    R
Sbjct:  146 IPLMAVVQRSKKKVRPVLDFRELNTYIDTYTAR 178          

HSP 7 Score: 34.6538 bits (78), Expect = 5.225e-80
Identity = 29/102 (28.43%), Postives = 39/102 (38.24%), Query Frame = 1
Query: 2878 SSGNGILERNHWTIKFHA-----DPRDIVFWYNAAPRDGINQDVGSSEGLFLYHWRFYRRVV-------------------VKPAPSKCTT*WPIGIVTGIL 3111
             SGNGI ER H T+K  A       R+ V+ YN  PRD        +  ++ Y  R     V                   VK    +C   +  G+VTG+L
Sbjct:  714 PSGNGIAERCHRTVKVIAARTGCSIREAVYRYNLMPRDDHTSATAPANVIYRYTVRDKNEAVTSSSEQSTNGPYVVGEPVWVKSRGGRCDDRYERGMVTGLL 815          
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A5S6QF31 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 6.883e-80
Identity = 65/139 (46.76%), Postives = 87/139 (62.59%), Query Frame = 2
Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLEN-AKVLGLRIKRDR 1786
            ++T +SDVC E L++W Q G  + ILDLK  YLQ+ V ++LW Y+      + Y LTRL FGLN AP IM  V+ +VL L P I   T  Y+D+I+VD + V  + V  HLAQYGL  K  E + N A+VLGL +  +R
Sbjct:  174 TYTARSDVCAEKLREWRQRGANIAILDLKKAYLQVRVEKSLWPYQTVMLRGRRYCLTRLGFGLNVAPTIMKAVVDRVLSLVPNISKGTSAYLDDILVDETVVSAHAVKRHLAQYGLECKSPEKVSNGARVLGLAVWGER 312          

HSP 2 Score: 78.1814 bits (191), Expect = 6.883e-80
Identity = 54/162 (33.33%), Postives = 83/162 (51.23%), Query Frame = 1
Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGENHL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWLKLWNSFGCSKLSTEKIKE 2439
            GR  V++   +I W +AS  AL V L  +G  +ED +WLR  E       +L    KG++L I   + +IE+M D + V  W++  L+  +        E L++RRL  +  L  +  + + + LV+S+EN+AD LT VP +WL           S E IKE
Sbjct:  398 GRWDVSSKRAKI-WVDASMLALGVALEVDGSVIEDGAWLRPEEARHINMAELDAVIKGLNLAIAWRMKQIELMTDSATVHRWIEDALSGRARLRTKATNEMLIRRRLETVLALVKEYDLAVTITLVRSSENKADCLTRVPSRWLS----------SVEPIKE 548          

HSP 3 Score: 66.6254 bits (161), Expect = 6.883e-80
Identity = 27/87 (31.03%), Postives = 48/87 (55.17%), Query Frame = 3
Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKID 2714
            H G+ +++YF +  +P   +  +   +        I P  +KW HG+L V    + +GID+ +     +L++ DCGPSRFS+W ++D
Sbjct:  572 HPGVRRTLYFCRRRDPRISKREVSRVVGTCDVCRSIDPAPVKWRHGVLEVPSIWQRVGIDVVHCGSEMYLSLTDCGPSRFSIWRRLD 658          

HSP 4 Score: 46.9802 bits (110), Expect = 6.883e-80
Identity = 19/52 (36.54%), Postives = 31/52 (59.62%), Query Frame = 2
Query: 2741 NLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896
            +LE +F ERG   ELL DN+ +F+   + +L+  W  +  ++CAY P+  G 
Sbjct:  668 HLESIFLERGAPDELLADNDTAFRSREVARLAEKWGTRIRFRCAYVPSGNGI 719          

HSP 5 Score: 43.8986 bits (102), Expect = 6.883e-80
Identity = 18/37 (48.65%), Postives = 27/37 (72.97%), Query Frame = 3
Query: 1824 KEITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934
            + +T+R   S CG+L+GHYPV   LRVA +++KR +N
Sbjct:  328 RRLTKRSVFSYCGELIGHYPVGNWLRVATAFVKRESN 364          

HSP 6 Score: 36.5798 bits (83), Expect = 6.883e-80
Identity = 14/28 (50.00%), Postives = 21/28 (75.00%), Query Frame = 3
Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVE 1373
            + L+   + +K+KVRPV DFRELN Y++
Sbjct:  146 IPLMAVVQRSKKKVRPVLDFRELNTYID 173          

HSP 7 Score: 34.6538 bits (78), Expect = 6.883e-80
Identity = 29/102 (28.43%), Postives = 39/102 (38.24%), Query Frame = 1
Query: 2878 SSGNGILERNHWTIKFHA-----DPRDIVFWYNAAPRDGINQDVGSSEGLFLYHWRFYRRVV-------------------VKPAPSKCTT*WPIGIVTGIL 3111
             SGNGI ER H T+K  A       R+ V+ YN  PRD        +  ++ Y  R     V                   VK    +C   +  G+VTG+L
Sbjct:  714 PSGNGIAERCHRTVKVIAARTGCSIREAVYRYNLMPRDDHTSATAPANVIYRYTVRDKNEAVTSSSEQSTNGPYVVGEPVWVKSRGGRCDDRYERGMVTGLL 815          
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A5S6QHX4 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 6.883e-80
Identity = 65/139 (46.76%), Postives = 87/139 (62.59%), Query Frame = 2
Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLEN-AKVLGLRIKRDR 1786
            ++T +SDVC E L++W Q G  + ILDLK  YLQ+ V ++LW Y+      + Y LTRL FGLN AP IM  V+ +VL L P I   T  Y+D+I+VD + V  + V  HLAQYGL  K  E + N A+VLGL +  +R
Sbjct:  174 TYTARSDVCAEKLREWRQRGANIAILDLKKAYLQVRVEKSLWPYQTVMLRGRRYCLTRLGFGLNVAPTIMKAVVDRVLSLVPNISKGTSAYLDDILVDETVVSAHAVKRHLAQYGLECKSPEKVSNGARVLGLAVWGER 312          

HSP 2 Score: 78.1814 bits (191), Expect = 6.883e-80
Identity = 54/162 (33.33%), Postives = 83/162 (51.23%), Query Frame = 1
Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGENHL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWLKLWNSFGCSKLSTEKIKE 2439
            GR  V++   +I W +AS  AL V L  +G  +ED +WLR  E       +L    KG++L I   + +IE+M D + V  W++  L+  +        E L++RRL  +  L  +  + + + LV+S+EN+AD LT VP +WL           S E IKE
Sbjct:  398 GRWDVSSKRAKI-WVDASMLALGVALEVDGSVIEDGAWLRPEEARHINMAELDAVIKGLNLAIAWRMKQIELMTDSATVHRWIEDALSGRARLRTKATNEMLIRRRLETVLALVKEYDLAVTITLVRSSENKADCLTRVPSRWLS----------SVEPIKE 548          

HSP 3 Score: 66.2402 bits (160), Expect = 6.883e-80
Identity = 27/87 (31.03%), Postives = 48/87 (55.17%), Query Frame = 3
Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKID 2714
            H G+ +++YF +  +P   +  +   +        I P  +KW HG+L V    + +GID+ +     +L++ DCGPSRFS+W ++D
Sbjct:  572 HPGVRRTLYFCRRRDPRISKREVSRVVGTCDVCRSIDPAPVKWRHGVLEVPSIWQRVGIDVVHCGSELYLSLTDCGPSRFSIWRRLD 658          

HSP 4 Score: 47.3654 bits (111), Expect = 6.883e-80
Identity = 19/52 (36.54%), Postives = 31/52 (59.62%), Query Frame = 2
Query: 2741 NLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896
            +LE +F ERG   ELL DN+ +F+   + +L+  W  +  ++CAY P+  G 
Sbjct:  668 HLESIFLERGAPDELLADNDTAFRSREVARLAEKWGTRIRFRCAYVPSGNGI 719          

HSP 5 Score: 43.8986 bits (102), Expect = 6.883e-80
Identity = 18/37 (48.65%), Postives = 27/37 (72.97%), Query Frame = 3
Query: 1824 KEITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934
            + +T+R   S CG+L+GHYPV   LRVA +++KR +N
Sbjct:  328 RRLTKRSVFSYCGELIGHYPVGNWLRVATAFVKRESN 364          

HSP 6 Score: 36.5798 bits (83), Expect = 6.883e-80
Identity = 15/33 (45.45%), Postives = 22/33 (66.67%), Query Frame = 3
Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVEVTPVR 1388
            + L+   + +K+KVRPV DFRELN Y++    R
Sbjct:  146 IPLMAVVQRSKKKVRPVLDFRELNTYIDTYTAR 178          

HSP 7 Score: 34.6538 bits (78), Expect = 6.883e-80
Identity = 29/102 (28.43%), Postives = 39/102 (38.24%), Query Frame = 1
Query: 2878 SSGNGILERNHWTIKFHA-----DPRDIVFWYNAAPRDGINQDVGSSEGLFLYHWRFYRRVV-------------------VKPAPSKCTT*WPIGIVTGIL 3111
             SGNGI ER H T+K  A       R+ V+ YN  PRD        +  ++ Y  R     V                   VK    +C   +  G+VTG+L
Sbjct:  714 PSGNGIAERCHRTVKVIAARTGCSIREAVYRYNLMPRDDHTSATAPANVIYRYTVRDKNEAVTSSSEQSTNGPYVVGEPVWVKSRGGRCDDRYERGMVTGLL 815          
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A0V1H8A0 (Gag-Pro-Pol polyprotein OS=Trichinella zimbabwensis OX=268475 GN=T11_8379 PE=4 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 2.249e-77
Identity = 64/153 (41.83%), Postives = 96/153 (62.75%), Query Frame = 2
Query: 1373 SHTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSE-SLENAKVLGLRIKRDRFCHLLSIRGNDRKG 1828
            SHT  +DVC + L++W + G  + ++DLK  YLQ+ + ++LW Y+   +  K Y LTRL FGLN AP +M  VL  VL  +P ++  T  Y+D+I+V+ S V V++V  HLA YGLT K  E + + A++LGL++  +R   L+  R ND  G
Sbjct:  317 SHTADADVCSQKLREWRRQGVNVALIDLKKAYLQIRIDKSLWPYQTVVFKGKRYCLTRLGFGLNVAPLVMKAVLNCVLSRDPDVRKGTSAYIDDILVNESVVAVDRVKRHLAHYGLTCKTHERAADGARLLGLKVWGERG-KLMWRRDNDVGG 468          

HSP 2 Score: 74.7146 bits (182), Expect = 2.249e-77
Identity = 52/145 (35.86%), Postives = 79/145 (54.48%), Query Frame = 1
Query: 1957 GR*TVTNSNCRIFWCEASSFALEVVLITNGDAVEDASWLRKGENHL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLTCVPVKWLK 2388
            GR  V+    +I W +ASS A+ V L   G  VEDA+WLR  +       +L    KG++L +   + RI +M D + V  W+   L+ ++      + E L++RR+ +I  L  +  + + V LVKSA N+AD LT VP +WLK
Sbjct:  541 GRWDVSAEEAKI-WVDASSLAIGVALEVGGSIVEDAAWLRPDDAQHINMAELDTVIKGLNLALSWQMRRIRLMTDSATVHRWVSDGLSGKARLKTKASGEMLIRRRVSMILSLVEEFGLELEVDLVKSACNKADELTRVPRRWLK 684          

HSP 3 Score: 58.5362 bits (140), Expect = 2.249e-77
Identity = 24/86 (27.91%), Postives = 46/86 (53.49%), Query Frame = 3
Query: 2454 HFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKI 2711
            H G+ +++YF +  +P   +  ++  +        + P   KW  G L V      +G+D+ + +   +LT++DCGPSRF+VW ++
Sbjct:  715 HPGIRRTLYFARRTDPTVSKRQVRQVITGCEPCKSLDPAPGKWKRGSLEVEEVWRRVGMDITHVRGRPYLTLIDCGPSRFAVWRRL 800          

HSP 4 Score: 49.2914 bits (116), Expect = 2.249e-77
Identity = 21/57 (36.84%), Postives = 31/57 (54.39%), Query Frame = 2
Query: 2726 SNTERNLEKVFRERGPVSELLMDNEKSFQFNSLKQLSSLWNIKPTYKCAYRPAEMGF 2896
            +N    LE VF ERG   ELL DN+ +F+     +  + W ++  Y+CAY P+  G 
Sbjct:  806 ANVTEQLEAVFCERGAPEELLTDNDTAFRGRIFTEFIARWGVRVRYRCAYVPSGNGI 862          

HSP 5 Score: 46.595 bits (109), Expect = 2.249e-77
Identity = 21/35 (60.00%), Postives = 25/35 (71.43%), Query Frame = 3
Query: 1830 ITRRIPLSLCGKLVGHYPVAA*LRVAYSYIKRIAN 1934
            +TRR   S CGKLV H+PV   LR+A +YIKR AN
Sbjct:  473 LTRRSVFSYCGKLVSHFPVCGWLRIAAAYIKRKAN 507          

HSP 6 Score: 37.7354 bits (86), Expect = 2.249e-77
Identity = 19/61 (31.15%), Postives = 35/61 (57.38%), Query Frame = 1
Query: 1210 RQDYEKEVKRWIKEDLLIPANDADH----GILPLLQQGKKTKGKFVRFLISESLIITLKSH 1380
            R  YE E+++WIK+  L+P ++++H    G+LPL+   ++ K K    +    L   ++SH
Sbjct:  258 RGAYEDELRKWIKDGWLVPYDESEHGPPKGLLPLMAVIQRNKKKVRPVMDFRELNAHIESH 318          

HSP 7 Score: 34.6538 bits (78), Expect = 2.249e-77
Identity = 30/102 (29.41%), Postives = 42/102 (41.18%), Query Frame = 1
Query: 2878 SSGNGILERNHWTIKFHADPR-----DIVFWYNAAPRDGINQDVGSSEGLFLY-----------------HWRFY--RRVVVKPAPSKCTT*WPIGIVTGIL 3111
             SGNGI ER H ++K  A  +     + V+ YN  PRDG N     +  +  Y                   RF     V V+P  ++C T    G VTG++
Sbjct:  857 PSGNGIAERCHRSVKVIAARKNCTVEEAVYLYNVTPRDGRNPWTAPANVVHAYVVRVRGVDRATEEPEEKDGRFAVGDSVWVRPPGARCDTRHQKGTVTGVV 958          
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000054470.1 (SMESG000054470.1)

HSP 1 Score: 192.2 bits (487), Expect = 1.212e-53
Identity = 101/160 (63.12%), Postives = 115/160 (71.88%), Query Frame = 2
Query: 1382 GKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLENAKVLGLRIKRDRFCHLLSIRGNDRKGNHSSYTAFFMR 1861
            G SDVC ESLK     GDQ+V+LDLKN ++QLHV EN  KY+K RY DK YYLTRLRF LNCA K+MS VLRKVL LNPRIKD+TDHY+D I VDTSKVQV +V N LAQ GLTTK ++S+EN K+LG RIKRD  C    I       N   YT  +MR
Sbjct:   87 GDSDVCGESLKNEDNGGDQVVMLDLKNAFVQLHVRENHLKYQKSRYKDKFYYLTRLRFELNCASKVMSLVLRKVLNLNPRIKDSTDHYIDGIAVDTSKVQVTEVGNRLAQIGLTTKPTDSIENTKILGFRIKRD-CCGSEEIIPVKSTANKLPYTVLYMR 245          
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000054470.1 (SMESG000054470.1)

HSP 1 Score: 190.66 bits (483), Expect = 8.628e-53
Identity = 101/160 (63.12%), Postives = 115/160 (71.88%), Query Frame = 2
Query: 1382 GKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLENAKVLGLRIKRDRFCHLLSIRGNDRKGNHSSYTAFFMR 1861
            G SDVC ESLK     GDQ+V+LDLKN ++QLHV EN  KY+K RY DK YYLTRLRF LNCA K+MS VLRKVL LNPRIKD+TDHY+D I VDTSKVQV +V N LAQ GLTTK ++S+EN K+LG RIKRD  C    I       N   YT  +MR
Sbjct:  118 GDSDVCGESLKNEDNGGDQVVMLDLKNAFVQLHVRENHLKYQKSRYKDKFYYLTRLRFELNCASKVMSLVLRKVLNLNPRIKDSTDHYIDGIAVDTSKVQVTEVGNRLAQIGLTTKPTDSIENTKILGFRIKRD-CCGSEEIIPVKSTANKLPYTVLYMR 276          
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000054470.1 (SMESG000054470.1)

HSP 1 Score: 190.66 bits (483), Expect = 9.750e-53
Identity = 101/160 (63.12%), Postives = 115/160 (71.88%), Query Frame = 2
Query: 1382 GKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSESLENAKVLGLRIKRDRFCHLLSIRGNDRKGNHSSYTAFFMR 1861
            G SDVC ESLK     GDQ+V+LDLKN ++QLHV EN  KY+K RY DK YYLTRLRF LNCA K+MS VLRKVL LNPRIKD+TDHY+D I VDTSKVQV +V N LAQ GLTTK ++S+EN K+LG RIKRD  C    I       N   YT  +MR
Sbjct:  124 GDSDVCGESLKNEDNGGDQVVMLDLKNAFVQLHVRENHLKYQKSRYKDKFYYLTRLRFELNCASKVMSLVLRKVLNLNPRIKDSTDHYIDGIAVDTSKVQVTEVGNRLAQIGLTTKPTDSIENTKILGFRIKRD-CCGSEEIIPVKSTANKLPYTVLYMR 282          
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000013825.1 (SMESG000013825.1)

HSP 1 Score: 102.064 bits (253), Expect = 1.931e-51
Identity = 51/136 (37.50%), Postives = 84/136 (61.76%), Query Frame = 2
Query: 1376 HTGKSDVCDESLKKWLQMGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPKIMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTTKLSE---SLENAKVLGLRI 1774
            ++ ++ VC+E++++W   G+++  LDL + Y+Q+ V E++WKY+    N+K Y LTRL FG+N A  IM+ ++  VL LN RIK     Y+D+I +D   V   KV   L+++ L TK  E   S +  ++LGL +
Sbjct:  372 YSDEAVVCNETIREWRNKGNKIATLDLSDAYMQIRVDESMWKYQSCIINEKRYALTRLGFGINIALGIMTEIVNHVLGLNDRIKQEASAYIDDIFIDEEVVPAEKVKAWLSKFNLMTKEIERPTSTKALRILGLSV 507          

HSP 2 Score: 57.3806 bits (137), Expect = 1.931e-51
Identity = 32/116 (27.59%), Postives = 57/116 (49.14%), Query Frame = 3
Query: 2451 HHFGLEKSMYFIQSENPETDQESIKVALRKRTEYSIIVPLSIKW*HGILVVT*N*ESIGIDLKNYKESTFLTMMDCGPSRFSVWMKIDREDAQTLKEIWRKYFEKEAQYQNYLWIM 2798
            + FG ++  + I+          +K  + K  E   I P S+K   G L V  + + + ID+    +  FLT++DCGPSRF++W +I  + A  + +   + F +     N+ WI+
Sbjct:  736 YDFGGDRLKFLIEKSGINLSLNELKEIIEKCDECQSIDPHSVKISKGQLEVKDSWKRLAIDVTKLHQKRFLTIIDCGPSRFAIWREIRNKCADKICKQLEQAFYERGLLMNFCWII 851          

HSP 3 Score: 56.225 bits (134), Expect = 1.931e-51
Identity = 42/123 (34.15%), Postives = 68/123 (55.28%), Query Frame = 1
Query: 2011 SFALEVVLITNGDAVEDASWLRKGEN----HL*MWRKLMRC*KGISLPIQ*-VNRIEMMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITIFVCLVKSAENRADVLT 2364
            S  +   L  +G+ +EDA WLRK ++    +L  ++ ++   KGI+L I+  +  +++M D   V SW+   L +E       + E LVKRRL IIKEL  +  I   +  V + +N++DVLT
Sbjct:  583 SIVIGAALEIDGNIMEDACWLRKKKDVKHINLCEFKAIV---KGINLCIKWNLKFVKIMSDNKSVVSWVHNALTSERKITTKASSEMLVKRRLSIIKELITEYEIKPKIEYVPTNKNKSDVLT 702          

HSP 4 Score: 35.4242 bits (80), Expect = 1.931e-51
Identity = 14/29 (48.28%), Postives = 21/29 (72.41%), Query Frame = 3
Query: 1290 LALITTGKENKRKVRPVFDFRELNNYVEV 1376
            + L    ++NK K+RPVFD R LN+Y++V
Sbjct:  343 VTLFPVMQKNKSKIRPVFDLRALNHYLDV 371          

HSP 5 Score: 34.6538 bits (78), Expect = 1.931e-51
Identity = 19/40 (47.50%), Postives = 24/40 (60.00%), Query Frame = 3
Query: 1821 EKEITRRIPL-SLCGKLVGHYPVAA*LRVAYSYIKRIANG 1937
            E+ I  R  L SLC +L G  P A  LR A SY+KR++ G
Sbjct:  527 EENIMNRQELYSLCSQLTGILPSAGWLRPACSYLKRLSEG 566          
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000018147.1 (SMESG000018147.1)

HSP 1 Score: 166.392 bits (420), Expect = 1.504e-47
Identity = 91/116 (78.45%), Postives = 93/116 (80.17%), Query Frame = 1
Query: 4357 NFKLSLEKDIVGLTLDGAVVNKKFIRHAEIIEQLCLNHGLHLGVSETLYKKKNLERDVGDASLVDTDYGSETDGFDENADIEFIEEDYSDGETDYKELLLKSRKLAKFIKLSSVKN 4704
            NFKLS EKDIVG T DGA VNKKFIR AEII QLCLNH +HLGV ETLYKK NLERDV DASL DTD  SE   FDEN DIEFIEEDYS  ETDYKELLLKSRKL K IK  S+KN
Sbjct:    3 NFKLSPEKDIVGSTFDGAAVNKKFIRPAEIIGQLCLNHVIHLGVCETLYKK-NLERDVCDASLFDTDDASERGEFDENTDIEFIEEDYSYEETDYKELLLKSRKLVKLIKRYSLKN 117          
The following BLAST results are available for this feature:
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5S6QJ614.906e-8341.48Uncharacterized protein OS=Trichuris muris OX=7041... [more]
A0A5S6Q7P65.225e-8046.76Uncharacterized protein OS=Trichuris muris OX=7041... [more]
A0A5S6QF316.883e-8046.76Uncharacterized protein OS=Trichuris muris OX=7041... [more]
A0A5S6QHX46.883e-8046.76Uncharacterized protein OS=Trichuris muris OX=7041... [more]
A0A0V1H8A02.249e-7741.83Gag-Pro-Pol polyprotein OS=Trichinella zimbabwensi... [more]
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000054470.11.212e-5363.13SMESG000054470.1[more]
SMESG000054470.18.628e-5363.13SMESG000054470.1[more]
SMESG000054470.19.750e-5363.13SMESG000054470.1[more]
SMESG000013825.11.931e-5137.50SMESG000013825.1[more]
SMESG000018147.11.504e-4778.45SMESG000018147.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034308 ID=SMED30034308|Name=Integrase catalytic domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5929bp
TCGTGATTGTCGGAATAATTCTAAAAATTGTCTCACAAGCTAGCGTCGCA
AAGATGGACCTTCAAAAAATTTTTTAAAGCCCTACGAAGGAATAGATGAT
TTTTCTACATGCCTAAAAAAAGTTAAAGTTAATGTCCAACCATCAAAAAA
TCGAAAATTTGGCCTTTGTTTTCCAATTGCTGCTTGATGGACCAACCACC
TGACGGGAAGGACAAAGAAAACTGTGACACTATAGAAGAAGCTCTAACAG
ATGCCTTTTCGACGAACGGCTTTTAGGCTTACGACACGTTTCGTAATCGA
TTATGGAATGGAGAACCAATATATTTTTTGCTTGCAGACCTGCCGCAATT
GGCTACACTGGACAGGATAAATGATGACGGCTTCTCAAAGGAGCATTCGT
AATTGGACTCCCATCAATGGTTTCCAACCAACTTAGAGCTTCAGCAAGGA
TCTTTCAAATGCACCTTTCAAAAGTTGTTCGATAATCTCGAGCTCTACTA
TCCGAACAAAATGGCTCTACTGGTCTTATTGCAGTGAAAAGAAGTGGTTT
TGAACTGTGTAAAGAAATCAAACTACACAATGAATGTCGAAAATCCAGTC
ATTTCAAAAACAAATACCCTACTCATGTGTTGGACATGCGGAATCAAAAG
GCATTCGTCATGACAATGCTCATCAAACTCACAAGGAAACGCCAGAGGTG
AAACTGGAGCGGTTTCTCATTGACATCAGGGATGGTGCGAGTACTTGTTA
GACTCAGAGTGAATGGAAAGCCGTGCACCGAACTAGTCGATTCCGATTGA
TTACAAACCAATATTTCCCGAATCTATGCAGAAGGAATTGGTAAAGCTAG
AGATGCTGTTGCCATAGATGGAAGAAGAGTTCGATGTGAATGAGAAAGTA
GGTACCATATTTCTGTTCGAGGAAAACGTTTTGTATTAAATTGCCTAATC
TTGTAGTCGGAGTGAATGTTATTTTAGGTCTCGATGCGATCGGACGTCAT
AGTGGAGTTTCGATTGACAATTATGGCGTACAGTTTGGTGAATGCGTCCG
AGTATCTATGTCGGCATTAATTTAAGAACAAGTGAAAATCGATGAAAAAG
ATTTTGCAAAGAAGTTTCGACTGAGAAAAATGGATCGTGTCCTTAAAGTG
GAGAGACAAACTCGTCTTCTTGAAAAATCATGTAGCTATATGCAGTGAAA
CCAGAAATACGACAGGATTACGAGAAGGAGGTCAAGCGATGGATTAAGGA
AGACTTGCTGATTCCGGCGAATGACGCCGATCATGGTATCTTGCCCTTAT
TACAACAGGGAAAGAAAACAAAAGGAAAGTTCGTCCGGTTTTTGATTTCA
GAGAGCTTAATAATTACGTTGAAGTCACACCGGTAAGAGTGATGTATGTG
ACGAAAGTTTGAAGAAATGGTTACAAATGGGAGATCAGTTGGTAATACTT
GATTTAAAGAATACGTATTTGCAGTTGCATGTCAGCGAAAATCTTTGGAA
ATACAAAAAATTTCGATACAATGACAAGCTGTATTATTTAACAAGATTAA
GATTCGGTCTCAACTGTGCTCCAAAAATAATGTCTCCAGTACTCAGAAAA
GTATTATGTCTCAATCCAAGAATAAAAGATGCGACAGATCATTACGTTGA
TAACATCGTTGTTGACACGAGCAAAGTTCAAGTTAACAAGGTCGTGAATC
ACTTAGCTCAATATGGCTTGACTACAAAATTATCAGAGTCACTAGAAAAT
GCAAAGGTTCTTGGTCTCAGAATAAAACGTGATCGTTTTTGCCACCTGTT
GTCGATCAGAGGAAATGATCGAAAAGGAAATCACTCGTCGTATACCGCTT
TCTTTATGCGGTAAGCTTGTTGGGCATTATCCAGTTGCAGCATAGCTCAG
AGTAGCCTACAGTTATATTAAAAGAATTGCAAACGGTATGAAATTTGATG
GAAGGTGGACGGTGAACGGTAACTAATAGTAATTGCAGGATTTTTTGGTG
TGAAGCGAGTAGTTTCGCTTTAGAGGTTGTGCTGATAACAAATGGCGATG
CTGTTGAAGACGCTTCGTGGCTCAGAAAAGGCGAGAATCACTTATAAATG
TGGCGGAAATTGATGCGGTGCTAAAAAGGAATTAGCTTGCCAATTCAATG
AGTTAATAGAATTGAAATGATGATAGATGGATCAAAGGTAGCAAGCTGGT
TAAAAACAGTGCTGAATAATGAAAGCGGAAATTGGATCTATGGAAATTTA
GAAACGCTTGTTAAGCGCCGCCTAGGAATAATCAAGGAACTAACTGCCGA
CGGAAGTATAACTATTTTTGTATGTTTAGTGAAGTCAGCAGAGAACCGAG
CAGATGTCCTCACGTGCGTTCCAGTGAAATGGCTGAAGCTTTGGAATTCC
TTCGGATGTTCCAAACTATCAACTGAGAAAATAAAAGAACGCCACGCAAA
CATCATTTCGGCTTAGAAAAGTCAATGTACTTCATCCAATCGGAAAATCC
GGAAACCGATCAAGAAAGCATAAAAGTCGCCTTGAGAAAACGTACAGAAT
ACAGTATAATCGTACCATTATCGATTAAGTGGTAGCATGGGATACTAGTG
GTAACGTAAAATTGAGAGAGTATAGGGATTGATCTCAAAAACTACAAGGA
ATCCACATTTTTGACAATGATGGACTGTGGGCCAAGCAGGTTTTCAGTGT
GGATGAAAATAGACCGAGAAGACGCTCAAACACTGAAAGAAATTTGGAGA
AAGTATTTCGAGAAAGAGGCCCAGTATCAGAATTACTTATGGATAATGAA
AAAAGTTTTCAATTTAATTCTCTCAAACAGTTATCTAGCCTATGGAATAT
TAAGCCAACCTACAAATGCGCTTACCGTCCAGCGGAAATGGGATTTTAGA
AAGAAATCACTGGACGATAAAATTTCATGCAGATCCTCGGGATATCGTTT
TCTGGTACAACGCCGCACCTAGAGATGGCATCAATCAGGACGTAGGTTCG
TCAGAAGGATTGTTCTTGTATCATTGGAGATTTTATCGAAGGGTCGTGGT
AAAGCCGGCACCATCAAAGTGTACTACTTGATGGCCCATTGGAATTGTGA
CTGGAATTCTGCCACAAACATTGAAGTGGATGGAACATCGAGACACTTAT
CGACAACCGACCAGTAGTGGAAGAAAATATGACTGACGATAAATCTGAAA
ATCGATCTGAGAAAGACCAAGCAAGTGAGTTGCTACATGTGAAAACTATC
AGAGACGACAACGTAGGAACCGCTTTATCTTGATCAGTATGACTTGGATA
CATCGTACTGATTACGGGGAATGTGCAATATTTTGTGTCTACTTTGACAC
TGTTCCATAATAGTGATTGAACCGTGAGACTATTATGCAATAAGTTTAAC
GACACTTTCAGCACAACATATTACGTTGCGGTAATTAATATGTTTATAAA
ATGTCATGTGCTCAAAATAAATTTATCTTTGTTTTATTAGAAATTGTCTA
ACAATTTTTCAAAAAATTGTCTATAAAAATGTAAATATTGGGTAACAAAA
GAATTTTAAATACTAGTAAATTTCATTCAAGGTTTTCATAATTTCTTAGA
ATCAGATTCTTATCGAATATTTTCTCAACTTGATTTAGATAAAATAACAT
CCCAATTAACCAATATCTTCCTTTTCTTTTCAATATATTCTGAATCACCC
TGAAATCATCAATTTTCCAAAACTATGCCCTTCTTAAAAAATATATTCAA
CCAACTAGATCTTCAAAAACATACAATTTACTCTTAACCAGTCATTCCTC
CTTAAATGGACAATCTTTATATATTATTTTTCATACAAATCACCACTTAG
TTAATGTTTACTTTAAAATAACAATGTTCACACATCCAAAACTTGAAGGA
CAGTGTCAAAAAATTATAAAATGTTCTGGCAATTCAGCGACTAGTCTTCG
ATAAACCAATTCATACAAAGTTATTCACCCGACAAGCAGTGAGTGAGAAA
CGAACGGTGACAATGGATATGTTGGTAAAGACAATGACGTTAAAAGAGAT
TGTTAGTGGTCTGGCAACTGACAACATGCTATTACAAATAGTAAATACAT
TCGTCAATCAATATTTCGTGATGGATTCACACTTCCGAAAAATGAAAGCT
CTGTGATGAAATTGGTCCACGAAGAGTTTGATAAGAAAAAACCTTTGATG
ATTGAAAATATTCGTAAGTTGCAATATTCAGTTTTTCTATTGATGAATGA
ACAAGTATAAGAGGTCGAAGATATTTTGGAAAAAACAGGACTGATTCGCA
TCTTAGGCTCATGCTCTGCTCTGGAAATAATTGATATTGTGAAAGATCAT
TTAAATAATTTTAAATTATCGCTAGAAAAGGATATAGTGGGCTTAACACT
TGATGGTGCAGTGGTCAACAAAAAGTTTATTCGTCATGCTGAAATAATTG
AACAGTTGTGCCTTAATCATGGCCTTCATCTGGGAGTTAGCGAAACTCTA
TACAAAAAGAAGAATTTAGAGCGAGATGTTGGTGACGCTTCTCTTGTCGA
CACCGATTATGGTTCTGAAACTGATGGGTTTGACGAAAATGCTGATATTG
AATTCATTGAAGAAGATTATTCTGACGGAGAGACTGACTACAAGGAACTT
CTTTTGAAATCTCGAAAACTTGCTAAATTTATCAAGCTATCTTCCGTGAA
AAATCAAGTTTTCCAATTGTATGTTGTTTGTGAGTTAGTTCATGAGAGAA
CTCCTCTTGGACGTTAAAACACGATGGAATTCTTTTCCGACAATGTTGGA
ATCACTGGTAAAAACTGAAAACTGAATTAGACTAACTCTTGCCGATTTTA
ACTCTTCTCACTTCAACGACGTTAATTTTGATGATCTTAAAAATATTCCC
AACGCAATGTAGCCGATTAATCTGGCAGTGGAGAAGTAGAGAAGATGCTA
CGTTAGTGACAGTTGATACAATCATTACGATTTTGCTCAATAAACTCGCT
GAAATGAATGATGATATCAGTTAAACATTGTGTGGAAATTTGAAGCTCTG
AATCAATGAGCGATGGAATACTGAACCTGTTGAGAAGTCTCAAGGATTGT
TCAATAGCACCTACAAAAATACACCAAATTTTTCTGGAAAGCTTGCATCC
CGAATTTTTCGAGTCGTTGATGTCCAAATGTCTGTGCCCGAACTTGATAA
CGCTCAATAGGAGCATTTAAAAAAATCTCTTAATGCGCTTGTTTTCCAAA
AATATTATTATAAGTCACGGCAAAAGAAAAATTTCATTTGGTTAATAATA
AACTATTAGTTGAATAAAAATCTAGTTATGGCTTTATGACTTTTTTTAAA
AAACCAGCTGTTTTTTGAAAATAAAGAACAGGAAACAACTGTTTTTTGAA
AATAAAAAAAGGAAACAGCTGTTTTTTTTAAAGTACTGTTTTTAAGAACG
GATTAAGCTACACCTGGTGCTAAACCTTCAAAATTGCCAAATAAAAATTT
AGTTTAATTTTGAATAAAGTTGCTATTTGTAAGATATAATATATTTGTTG
ATTTTGATCTTGAATACTCGTGTTTAGTGAACAGTCACATCGTTAATTGT
TTAGACACGTAAATTCCCCTAATTACTTTTACAAGTAAATCCTAAAAATA
ACCATATATTTATCATAATGGATAGTATTAATACAGACATACAATATTTG
TCTTACAAAATTATTACGGCATATAAACTCAGAAATATAAGAGTTTAGCA
TTTCATAAGGAGTTCCATTCATTCTCTTGAATTTGCGTTAGAAACGAGAC
CACACAGTTACAATATGAAGGTCCATTGTTGATAAATACGACATCTGAAA
TTCCCAACTTGTTGATAAGTGCCGAAACAATCTGACAAGAAGAATGTCTA
GCAATACTTTCTTTTGGCAATGACTGTTT
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protein sequence of SMED30034308-orf-1

>SMED30034308-orf-1 ID=SMED30034308-orf-1|Name=SMED30034308-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=100bp
MMIDGSKVASWLKTVLNNESGNWIYGNLETLVKRRLGIIKELTADGSITI
FVCLVKSAENRADVLTCVPVKWLKLWNSFGCSKLSTEKIKERHANIISA*
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protein sequence of SMED30034308-orf-2

>SMED30034308-orf-2 ID=SMED30034308-orf-2|Name=SMED30034308-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=146bp
MGDQLVILDLKNTYLQLHVSENLWKYKKFRYNDKLYYLTRLRFGLNCAPK
IMSPVLRKVLCLNPRIKDATDHYVDNIVVDTSKVQVNKVVNHLAQYGLTT
KLSESLENAKVLGLRIKRDRFCHLLSIRGNDRKGNHSSYTAFFMR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004523RNA-DNA hybrid ribonuclease activity
GO:0003676nucleic acid binding
GO:0008270zinc ion binding
Vocabulary: biological process
TermDefinition
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
GO:0015074DNA integration
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR012337RNaseH-like_sf