G_PROTEIN_RECEP_F1_2 domain-containing protein

Overview


Name	G_PROTEIN_RECEP_F1_2 domain-containing protein
Smed ID	SMED30034274
Length (bp)	1087

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30034274) t-SNE clustered cells

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30034274) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30034274) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034274

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30034274	h1SMcG0006570	SmedASXL_001519	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30034274	h1SMcG0006570	dd_Smed_v4_79416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30034274	h1SMcG0006570	dd_Smed_v4_79416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30034274	h1SMcG0006570	dd_Smed_v4_79416_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30034274	h1SMcG0006570	dd_Smed_v6_73357_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30034274	h1SMcG0006570	dd_Smed_v6_79416_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: TRHR (thyrotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:12299])

HSP 1 Score: 53.1434 bits (126), Expect = 3.819e-7
Identity = 68/318 (21.38%), Postives = 131/318 (41.19%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFF---------VLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCML-----------------LGIGFIWGINLVSNVPYNYVTIFG-FYIVPLVIIIGLY--------CSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWW--------AMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTPPK 1040
            + GN++V++ V   KHMRT TN  + +LA+ D ++            +       T+ ++ +W++       I  + +         +   T+ER++AI +P+K + + + ++    II +    S +CML                 +  G+    N  S +   Y+  FG FY+VP+++   LY         + +        +   + S+++ +NL+V   N+       S   V   L +  +  A+ W          S+  + F  N F L   I    NS +N  IY +   +F+  F ++  C+Q P +
Sbjct:   40 IVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMV-----------LVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPI---YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTE 343

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Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFF---------VLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCML-----------------LGIGFIWGINLVSNVPYNYVTIFG-FYIVPLVIIIGLY--------CSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWW--------AMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTPPK 1040
            + GN++V++ V   KHMRT TN  + +LA+ D ++            +       T+ ++ +W++       I  + +         +   T+ER++AI +P+K + + + ++    II +    S +CML                 +  G+    N  S +   Y+  FG FY+VP+++   LY         + +        +   + S+++ +NL+V   N+       S   V   L +  +  A+ W          S+  + F  N F L   I    NS +N  IY +   +F+  F ++  C+Q P +
Sbjct:   40 IVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMV-----------LVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPI---YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTE 343

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: TAAR9 (trace amine associated receptor 9 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:20977])

HSP 1 Score: 50.8322 bits (120), Expect = 2.051e-6
Identity = 30/100 (30.00%), Postives = 51/100 (51.00%), Query Frame = 3

Query:  219 FGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFS 518
            FGNLLV+IA+  FK + T TN L+A+LA  DFL+G   +P      +        +  +  +       F   ++F +  I+V+R++A+  P+     F+
Sbjct:   48 FGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDS--YCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFT 145

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: HTR2C (5-hydroxytryptamine receptor 2C [Source:HGNC Symbol;Acc:HGNC:5295])

HSP 1 Score: 50.0618 bits (118), Expect = 4.485e-6
Identity = 60/221 (27.15%), Postives = 101/221 (45.70%), Query Frame = 3

Query:  231 LVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPN-----------IFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIG--------------FIWGINLVSNVPYNYVTIFGF--YIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVE-----KLNKAE 797
            LV++AV   K +   TN  + +LA+ D L+G + +PL +              + Y+++W +P            +FS  +I  +  I+++R+VAI  P++     SRTK I+ I I+      W + +G+               F+     V N P N+V I  F  + +PL I++  YC T+  LR  Q  +L H  + +   LS++     K N AE
Sbjct:   73 LVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLA------------ILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIV------WAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDP-NFVLIGSFVAFFIPLTIMVITYCLTIYVLRR-QALMLLHGHTEEPPGLSLDFLKCCKRNTAE 273

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Query:  231 LVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPN-----------IFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIG--------------FIWGINLVSNVPYNYVTIFGF--YIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVE-----KLNKAE 797
            LV++AV   K +   TN  + +LA+ D L+G + +PL +              + Y+++W +P            +FS  +I  +  I+++R+VAI  P++     SRTK I+ I I+      W + +G+               F+     V N P N+V I  F  + +PL I++  YC T+  LR  Q  +L H  + +   LS++     K N AE
Sbjct:   73 LVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLA------------ILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIV------WAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDP-NFVLIGSFVAFFIPLTIMVITYCLTIYVLRR-QALMLLHGHTEEPPGLSLDFLKCCKRNTAE 273

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: ador-1 (ADenOsine Receptor homolog [Source:UniProtKB/TrEMBL;Acc:Q1ZXT2])

HSP 1 Score: 56.6102 bits (135), Expect = 1.078e-8
Identity = 73/281 (25.98%), Postives = 126/281 (44.84%), Query Frame = 3

Query:  213 IVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWV--IPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSN--------------VPYN---YVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKK 998
            I F NLLVL      KH+RT TN  + +LAL DFL GA+ +        ++  +T     FY  L+V  I  I   ++ F +L I ++++V I    + +I  SR K  I+++    ++     +L +  ++G     +              V Y    YV  F   + P  II+ LY S   ++R  ++++      +++     E+      KL   L I++V   + + P  I   + Y+   F +N  +L + I+   +  +N  IYA  +P FKK
Sbjct:   18 ISFSNLLVLWVYVRSKHVRTVTNTYIFSLALTDFLAGALGI-----PLTVVSVMTRKPRTFYGCLFVHLILCILCTISTFHMLAIAIDKYVTIC--CRDRIFSSRRKRAIFLLTTSWILGLLVAILPLFNVFGFAETQSLFIENGEMCHFTMVVDYRYLVYVIFFSTILAPTAIIVLLYSSIYSRIRTEEKQVKCLLRQSER-----ERRMAGRRKLIRILLILVVSYGICWYPLYIINTIDYFWPEFSINSLTLWTVIMSHMSCALNPLIYAYGMPGFKK 286

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: ador-1 (ADenOsine Receptor homolog [Source:UniProtKB/TrEMBL;Acc:Q1ZXT2])

HSP 1 Score: 56.6102 bits (135), Expect = 1.101e-8
Identity = 73/281 (25.98%), Postives = 126/281 (44.84%), Query Frame = 3

Query:  213 IVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWV--IPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSN--------------VPYN---YVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKK 998
            I F NLLVL      KH+RT TN  + +LAL DFL GA+ +        ++  +T     FY  L+V  I  I   ++ F +L I ++++V I    + +I  SR K  I+++    ++     +L +  ++G     +              V Y    YV  F   + P  II+ LY S   ++R  ++++      +++     E+      KL   L I++V   + + P  I   + Y+   F +N  +L + I+   +  +N  IYA  +P FKK
Sbjct:   18 ISFSNLLVLWVYVRSKHVRTVTNTYIFSLALTDFLAGALGI-----PLTVVSVMTRKPRTFYGCLFVHLILCILCTISTFHMLAIAIDKYVTIC--CRDRIFSSRRKRAIFLLTTSWILGLLVAILPLFNVFGFAETQSLFIENGEMCHFTMVVDYRYLVYVIFFSTILAPTAIIVLLYSSIYSRIRTEEKQVKCLLRQSER-----ERRMAGRRKLIRILLILVVSYGICWYPLYIINTIDYFWPEFSINSLTLWTVIMSHMSCALNPLIYAYGMPGFKK 286

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: ser-5 (SERotonin/octopamine receptor family [Source:UniProtKB/TrEMBL;Acc:G5EBX8])

HSP 1 Score: 49.6766 bits (117), Expect = 1.873e-6
Identity = 35/114 (30.70%), Postives = 60/114 (52.63%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNW--------LWVIPNI-FSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKL 530
            +FGNLLVL   F  +  RTNT +LV  L L DFL+G + +P+                ++  W        LWV  ++ F   ++  + +I+V+R++A+  P++ K I ++TK+
Sbjct:   77 IFGNLLVLF--FKARVGRTNTTLLVWNLGLTDFLVGVIVLPMGAVYL-----------IYRKWIFGRFLCRLWVAADVTFCTCSVVTICVISVDRYLAVTRPLRYKSIVTKTKV 177

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: taar20r (trace amine associated receptor 20r [Source:ZFIN;Acc:ZDB-GENE-060413-21])

HSP 1 Score: 51.9878 bits (123), Expect = 4.769e-7
Identity = 77/289 (26.64%), Postives = 135/289 (46.71%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFV-----------LLITVERFVAIAYPM--KLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNVPY---------NYV--TIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKL--NKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNIL--QVSNSLVNFFIYAIKLPQFKK 998
            VF NLLV+I++  FK + T TN+++ +LA+ D L+G V     I +                  W   + F  L + FV           +LI V+R+VA+ +P+    KI  ++T + I +  +        +L+  G+ +G +  ++V Y         N+V   +F  +I P ++II LY   L+      Q++   +S  K      E L   K+E K  ++L I+++  +L Y+P        Y++ S  +N  + ++ +L    +NS +N  IYA+  P FKK
Sbjct:   64 VFLNLLVIISISHFKKLHTPTNMIILSLAVTDLLVGLVMPVEAIRMI--------------ETCWYFGDTFCGLHLLFVSLLIAASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWVCSSAYNTALLINNGY-FGTSHRTDVCYGECLFMSSFNWVVTDLFLSFIFPCLLIISLY---LRIFYVVHQQVKVINSLMKGGKCVTEGLVKRKSESKAALTLGIIVLVYLLCYIP--------YFICSITVNSSTTINGLLFAVCANSGLNPLIYALFYPWFKK 326

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: taar20g (trace amine associated receptor 20g [Source:ZFIN;Acc:ZDB-GENE-091116-61])

HSP 1 Score: 50.8322 bits (120), Expect = 1.196e-6
Identity = 82/292 (28.08%), Postives = 131/292 (44.86%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFV-----------LLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGI-----------GFIWGINLVS-NVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEK--LNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNILQV------SNSLVNFFIYAIKLPQFKK 998
            VF NLLV+I++  FK + T TN+++ +LA+ND L+G V       + +  I +T T        W   + F  L +FFV           LLI V+R+VA+ +P+      + TK++  I +     S +C    I              +G  LV  ++ +  + +F  +I P  +II LY   L+      Q++   +S  K+     E     K+E K  ++L I++   +L ++P  I    S  VNS         S  L V      +NS VN  +YA+  P FKK
Sbjct:   64 VFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLVGVV-------MPVEAIRMTET-------CWYFGDTFCGLYLFFVSLLLAASLGNLLLIAVDRYVAVCHPLLYTQKITITKMLTSICLCWACFSTYCTTFVIDNRNFDTSHRTDVCYGECLVMISLSWLVIDLFMSFIFPCTLIILLY---LRIFYVVHQQVKVINSLMKRGKCVTEGSVKRKSESKAALTLGIIVSVYLLCWIPYCI---CSLIVNS---------STALNVIIWTVYANSGVNPLVYALFYPWFKK 326

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: CR925820.11 (trace amine associated receptor 20r [Source:NCBI gene;Acc:100150617])

HSP 1 Score: 50.0618 bits (118), Expect = 1.910e-6
Identity = 74/278 (26.62%), Postives = 137/278 (49.28%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPM--KLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNV---------PYNYV--TIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEK--LNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNIL--QVSNSLVNFFIYAIKLPQFKK 998
            VF NLLV+I++  FK + T TN+++ +LA+ND LIG V     I +         T   F     +  ++    ++  ++LI V+R+VA+ +P+    KI  ++T + I +  + +      +L+  G+ +G +L ++V          Y+Y+   +F  +I P ++II LY   L+      Q++   +S  K      E     K+E K  ++L I++   +L ++P        Y++ S  +N  + ++ +L    +NS +N  IYA+  P FKK
Sbjct:   64 VFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLVMPIEAIRLIETCWYFGDT---FCALHLLFVSLLLAASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWVCLSAYNTALLINSGY-FGTSLRTDVCFGECLFMSSYSYILTDLFMSFIFPCLLIITLY---LRIFYVVHQQVKVINSLMKGGKCVTESSVKRKSESKAALTLGIIVTVYLLCWIP--------YFICSLTVNSSTALNGLLFAVCANSGLNPLIYALFYPWFKK 326

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: taar20q (trace amine associated receptor 20q [Source:ZFIN;Acc:ZDB-GENE-091116-85])

HSP 1 Score: 49.2914 bits (116), Expect = 3.821e-6
Identity = 77/293 (26.28%), Postives = 129/293 (44.03%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPV----FYNWLWVIPNIFSILAIFFV-----------LLITVERFVAIAYPM--KLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNVPYNYV-----------TIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKL--NKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNIL--QVSNSLVNFFIYAIKLPQFKK 998
            VF NLLV+I++  FK + T TN+++ +LA+ND LIG                     PV         W   + F  L +FFV           +LI V+R+VA+ +P+    KI  ++T L I +  + +      +    G+ +  +L ++V Y               +F  +I P  +II LY   L+      Q++   +S  K      E L   K+E K  ++L I++   +L Y+P        Y++ S  +N  + ++ +L    +NS +N  IYA+    FKK
Sbjct:   56 VFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLFM------------------PVEAIRLIETCWYFGDTFCGLHLFFVSLLLAASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLLSICLSWVCLSAYIITLSTNNGY-FDTSLKTDVCYGQCLVMMSFSWIVTDLFMSFIFPCTLIITLY---LRIFYVVHQQVKVINSLMKGGKCVTEGLVKRKSESKAALTLGIIVSVYLLCYIP--------YFICSLTVNSSTTINGLLFAVCANSGLNPLIYALFYTWFKK 318

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: taar20w (trace amine associated receptor 20w [Source:ZFIN;Acc:ZDB-GENE-060414-8])

HSP 1 Score: 48.9062 bits (115), Expect = 4.723e-6
Identity = 39/116 (33.62%), Postives = 60/116 (51.72%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFV-----------LLITVERFVAIAYPM--KLKIIFSRT 524
            VF NLLV+I++  FK + T TN+++ +LA+ND LIG V       + +  I  T T        W   NIF  L + F+           +LI V+R+VA+ +P+    KI  ++T
Sbjct:   46 VFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGVV-------MPIEAIRQTET-------CWYFGNIFCGLYLLFISLLMSASLSNLVLIAVDRYVAVCHPLLYPQKITITKT 147

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: HTR2C (5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled [Source:NCBI gene;Acc:100496012])

HSP 1 Score: 54.299 bits (129), Expect = 1.434e-7
Identity = 55/216 (25.46%), Postives = 98/216 (45.37%), Query Frame = 3

Query:  222 GNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPN-----------IFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGF---IWGINLVSNV---------PYNYVTIFGF--YIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKA 794
            GN+LV++AV   K ++  TN  + +LA+ D L+G +            +   S   + Y++ W +P            +FS  +I  +  I+++R+VAI  P++     SRTK       ++ + + W + +GI     + G+   S V           N+V +  F  + +PL+I++  YC T+Q L+  Q  +  +    KQ   SV  L K 
Sbjct:   73 GNILVIMAVSLEKKLQNATNFFLMSLAVADMLVGIL------------VMPVSLVTILYDYAWPLPRKLCPIWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTK------AMMKIAAVWTISIGISMPVPVIGLQDDSRVFVNSSCVLNDENFVLLGSFVAFFIPLIIMVFTYCLTIQVLQK-QATVFMYEEVPKQRRSSVNCLKKE 269

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: HTR2C (5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled [Source:NCBI gene;Acc:100496012])

HSP 1 Score: 53.9138 bits (128), Expect = 1.988e-7
Identity = 55/215 (25.58%), Postives = 100/215 (46.51%), Query Frame = 3

Query:  222 GNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPN-----------IFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGF---IWGINLVSNV---------PYNYVTIFGF--YIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNK 791
            GN+LV++AV   K ++  TN  + +LA+ D L+G + +P+ +              + Y++ W +P            +FS  +I  +  I+++R+VAI  P++     SRTK       ++ + + W + +GI     + G+   S V           N+V +  F  + +PL+I++  YC T+Q L+  Q  +  +    KQ   SV  L K
Sbjct:   84 GNILVIMAVSLEKKLQNATNFFLMSLAVADMLVGILVMPVSLVT------------ILYDYAWPLPRKLCPIWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTK------AMMKIAAVWTISIGISMPVPVIGLQDDSRVFVNSSCVLNDENFVLLGSFVAFFIPLIIMVFTYCLTIQVLQK-QATVFMYEEVPKQRRSSVNCLKK 279

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000006865.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:118467762:118507139:-1 gene:ENSXETG00000012361.1 transcript:ENSXETT00000006865.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 52.373 bits (124), Expect = 7.310e-7
Identity = 78/310 (25.16%), Postives = 143/310 (46.13%), Query Frame = 3

Query:  213 IVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILA-IFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIW----------------GINLVSNVPYNYVTIFGFYIVPLVIIIGLY-----CSTLQ-------KLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSF-GMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTPPKSIYS 1052
            IVFGN+LV+IA+     ++T TN+ + +LA  D ++G + VP    I +    L  T       LW   ++  + A I  + +I V+R++AI  P+K +++ ++ +  + + ++  + +    L  +   W                  + V+N+PY  V+    + VPLVI+I +Y      +T Q       K+R     + T+ S           L   E K   +L I++    L ++P  +   +  +  SF   N+F L  N L   NS +N  IY  + P F++ F ++LRC +T  + +++
Sbjct:   43 IVFGNMLVIIAIAKTPRLQTMTNVFITSLACADLIMGLLVVPPGATILVTGDWLFETT---VCELWTSVDVLCVTASIETLCVIAVDRYIAITSPLKYEMLVTKVRARLTVCLVWAISALISFLPIMNRWWRDTHNEEAKSCYDNPKCCDFVTNMPYAIVSSTISFYVPLVIMIFVYVRVFIVATRQVRLIEKDKVRFNGTPVPTNKSRRASRRRPSGLLAIKEHKALKTLGIIMGIFTLCWLPFFVANIIKVFCRSFIDDNVF-LFLNWLGYINSGLNPIIYC-RSPDFRRAFRKLLRCPRTVDRKLHA 347

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000006856.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:118467762:118507139:-1 gene:ENSXETG00000012361.1 transcript:ENSXETT00000006856.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.6026 bits (122), Expect = 1.204e-6
Identity = 78/310 (25.16%), Postives = 143/310 (46.13%), Query Frame = 3

Query:  213 IVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILA-IFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWG----------------INLVSNVPYNYVTIFGFYIVPLVIIIGLY-----CSTLQ-------KLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSF-GMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTPPKSIYS 1052
            IVFGN+LV+IA+     ++T TN+ + +LA  D ++G + VP    I +    L  T       LW   ++  + A I  + +I V+R++AI  P+K +++ ++ +  + + ++  + +    L  +   W                  + V+N+PY  V+    + VPLVI+I +Y      +T Q       K+R     + T+ S           L   E K   +L I++    L ++P  +   +  +  SF   N+F L  N L   NS +N  IY  + P F++ F ++LRC +T  + +++
Sbjct:   43 IVFGNMLVIIAIAKTPRLQTMTNVFITSLACADLIMGLLVVPPGATILVTGDWLFETT---VCELWTSVDVLCVTASIETLCVIAVDRYIAITSPLKYEMLVTKVRARLTVCLVWAISALISFLPIMNRWWRDTHNEEAKSCYDNPKCCDFVTNMPYAIVSSTISFYVPLVIMIFVYVRVFIVATRQVRLIEKDKVRFNGTPVPTNKSRRASRRRPSGLLAIKEHKALKTLGIIMGIFTLCWLPFFVANIIKVFCRSFIDDNVF-LFLNWLGYINSGLNPIIYC-RSPDFRRAFRKLLRCPRTVDRKLHA 347

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: phactr1 (phosphatase and actin regulator 1 [Source:Xenbase;Acc:XB-GENE-5959316])

HSP 1 Score: 50.0618 bits (118), Expect = 3.327e-6
Identity = 37/106 (34.91%), Postives = 58/106 (54.72%), Query Frame = 3

Query:  192 MAVEIPFIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTST---NPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMK 500
            M   I F   GNL+V+I+V  FK ++T TN+LV +LA+ DFL+G +     +  Y ++  LTS      VF      I  + S  +IF +  I+V+R+ A+  P+ 
Sbjct:   32 MLGAIIFTTVGNLMVIISVSHFKQLQTPTNVLVMSLAIADFLLGLL-----VMPYSMVRSLTSCWYFGEVFCKLHSCIDMMLSTTSIFHLFFISVDRYYAVCQPLH 132

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Taar9 (trace amine-associated receptor 9 [Source:MGI Symbol;Acc:MGI:3527454])

HSP 1 Score: 51.6026 bits (122), Expect = 6.287e-7
Identity = 31/101 (30.69%), Postives = 52/101 (51.49%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFS 518
            VFGNLLV+IA+  FK + T TN LVA+LA  DFL+G   +P      +        +  +  +       F   ++F +  I+++R++A+  P+     F+
Sbjct:   47 VFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGES--YCKFHTCFDTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFT 145

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824])

HSP 1 Score: 50.0618 bits (118), Expect = 2.221e-6
Identity = 67/318 (21.07%), Postives = 130/318 (40.88%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFF---------VLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCML-----------------LGIGFIWGINLVSNVPYNYVTIFG-FYIVPLVIIIGLY--------CSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWW--------AMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTPPK 1040
            + GN++V++ V   KHMRT TN  + +LA+ D ++            +       T+ ++ +W++       I  + +         +   T+ER++AI +P+K + + + ++    II +    S +CML                 +  G+    N  S +   Y+  FG FY+VP+++   LY         + +        ++  + S ++  NL++   N+       S   V   L +  +  A+ W          S+  + F  N F L   I    NS +N  IY +   +F+  F ++  C+Q P +
Sbjct:   40 IVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMV-----------LVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCGYKISRNYYSPI---YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTE 343

[Close]

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFF---------VLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCML-----------------LGIGFIWGINLVSNVPYNYVTIFG-FYIVPLVIIIGLY--------CSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWW--------AMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTPPK 1040
            + GN++V++ V   KHMRT TN  + +LA+ D ++            +       T+ ++ +W++       I  + +         +   T+ER++AI +P+K + + + ++    II +    S +CML                 +  G+    N  S +   Y+  FG FY+VP+++   LY         + +        ++  + S ++  NL++   N+       S   V   L +  +  A+ W          S+  + F  N F L   I    NS +N  IY +   +F+  F ++  C+Q P +
Sbjct:   40 IVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMV-----------LVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCGYKISRNYYSPI---YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTE 343

[Close]

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFF---------VLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCML-----------------LGIGFIWGINLVSNVPYNYVTIFG-FYIVPLVIIIGLY--------CSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWW--------AMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTPPK 1040
            + GN++V++ V   KHMRT TN  + +LA+ D ++            +       T+ ++ +W++       I  + +         +   T+ER++AI +P+K + + + ++    II +    S +CML                 +  G+    N  S +   Y+  FG FY+VP+++   LY         + +        ++  + S ++  NL++   N+       S   V   L +  +  A+ W          S+  + F  N F L   I    NS +N  IY +   +F+  F ++  C+Q P +
Sbjct:   40 IVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMV-----------LVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCGYKISRNYYSPI---YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTE 343

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Adra1a (adrenergic receptor, alpha 1a [Source:MGI Symbol;Acc:MGI:104773])

HSP 1 Score: 48.1358 bits (113), Expect = 8.444e-6
Identity = 48/211 (22.75%), Postives = 100/211 (47.39%), Query Frame = 3

Query:  210 FIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILA-IFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWC--MLLGIGFIWG----------INLVSNVP-YNYVTIFGFYIVPLVIIIGLYCS----TLQKLRNYQQEILTHSSSNKQSNLSVEKLN 788
            F V GN+LV+++V   +H+ + T+  +  LA+ D L+   S  L       I+   +   VF N +W   ++    A I  + +I+++R++ ++YP++   I ++ +       +  ++  W   +++ IG ++G          I  ++  P Y   +  G + VPL II+ +YC       ++ R  +  + T  S ++Q  L + + N
Sbjct:   39 FGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLL--TSTVLPFSAIFEILGYWAFGRVFCN-IWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRR------GVRALLCVWALSLVISIGPLFGWRQQAPEDETICQINEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN 240

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5IS66|5HT2C_PANTR (5-hydroxytryptamine receptor 2C OS=Pan troglodytes OX=9598 GN=HTR2C PE=2 SV=1)

HSP 1 Score: 55.4546 bits (132), Expect = 3.263e-7
Identity = 65/237 (27.43%), Postives = 109/237 (45.99%), Query Frame = 3

Query:  183 AYAMAVEIPFIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPN-----------IFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIG--------------FIWGINLVSNVPYNYVTIFGF--YIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVE-----KLNKAE 797
            A ++ V I   + GN+LV++AV   K +   TN  + +LA+ D L+G + +PL +              + Y+++W +P            +FS  +I  +  I+++R+VAI  P++     SRTK I+ I I       W + +G+               F+     V N P N+V I  F  + +PL I++  YC T+  LR  Q  +L H  + +   LS++     K N AE
Sbjct:   57 ALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLA------------ILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAI------VWAISIGVSVPIPVIGLRDERKVFVNNTTCVLNDP-NFVLIGSFVAFFIPLTIMVITYCLTIYVLRR-QALMLLHGHTEEPPGLSLDFLKCCKRNTAE 273

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|P34981|TRFR_HUMAN (Thyrotropin-releasing hormone receptor OS=Homo sapiens OX=9606 GN=TRHR PE=1 SV=1)

HSP 1 Score: 53.1434 bits (126), Expect = 1.834e-6
Identity = 68/318 (21.38%), Postives = 131/318 (41.19%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFF---------VLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCML-----------------LGIGFIWGINLVSNVPYNYVTIFG-FYIVPLVIIIGLY--------CSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWW--------AMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTPPK 1040
            + GN++V++ V   KHMRT TN  + +LA+ D ++            +       T+ ++ +W++       I  + +         +   T+ER++AI +P+K + + + ++    II +    S +CML                 +  G+    N  S +   Y+  FG FY+VP+++   LY         + +        +   + S+++ +NL+V   N+       S   V   L +  +  A+ W          S+  + F  N F L   I    NS +N  IY +   +F+  F ++  C+Q P +
Sbjct:   40 IVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMV-----------LVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPI---YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTE 343

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5QD04|TAAR9_MOUSE (Trace amine-associated receptor 9 OS=Mus musculus OX=10090 GN=Taar9 PE=2 SV=1)

HSP 1 Score: 51.6026 bits (122), Expect = 4.398e-6
Identity = 31/101 (30.69%), Postives = 52/101 (51.49%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFS 518
            VFGNLLV+IA+  FK + T TN LVA+LA  DFL+G   +P      +        +  +  +       F   ++F +  I+++R++A+  P+     F+
Sbjct:   47 VFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGES--YCKFHTCFDTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFT 145

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q923Y6|TAAR9_RAT (Trace amine-associated receptor 9 OS=Rattus norvegicus OX=10116 GN=Taar9 PE=3 SV=1)

HSP 1 Score: 50.8322 bits (120), Expect = 8.204e-6
Identity = 33/102 (32.35%), Postives = 50/102 (49.02%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIG-AVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFS 518
            VFGNLLV+ A+  FK + T TN LVA+LA  DFL+G  V     +           T   F+         F   ++F +  I+++R+VA+  P+     F+
Sbjct:   37 VFGNLLVITAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVEGCWYFGDTYCKFHT---CFDTSFCFASLFHLCCISIDRYVAVTDPLTYPTKFT 135

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|O46639|TRFR_BOVIN (Thyrotropin-releasing hormone receptor OS=Bos taurus OX=9913 GN=TRHR PE=3 SV=1)

HSP 1 Score: 50.8322 bits (120), Expect = 9.449e-6
Identity = 71/316 (22.47%), Postives = 136/316 (43.04%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFF---------VLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCML-----------------LGIGFIWGINLVSNVPYNYVTIFG-FYIVPLVIIIGLYC------------STLQKLRNYQQEILTHSSSNKQSNLSVEKLN---KAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNS-FGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTP 1034
            + GN++V++ V   KHMRT TN  + +LA+ D ++            +       T+ ++ +W++       I  + +         +   T+ER++AI +P+K + + + ++    II +    S +CML                 +  G+    N  S +   Y+  FG FY+VP+++   LY             S  ++  N  +   TH + N  S  S    N    +  ++T  L++V++   L ++P      ++ +++S F  N F L   I    NS +N  IY +   +F+  F ++  C+Q P
Sbjct:   40 IVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMV-----------LVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVVSCGYKISRNYYSPI---YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSNMWKNDSTHQNKNLNSKTSNRYFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKP 341

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A1I8JHW7 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 2.073e-10
Identity = 77/297 (25.93%), Postives = 142/297 (47.81%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFI----WGINLVSNVPYNYVTI-----------FGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNS-----FGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQIL---RCRQTPP 1037
            V GN L + AV   + MR  TN LVA+LA  D L+G V++PL +              +  N L V    F+ ++IF +L I++ERFVA+ +P++ +++     + + +++       W     +GF+    W +   S+   ++ ++           FG  +VPL+ ++ +Y        +Y  ++L    S++ SN   E  +  E +   SL++V++     +VP  +   +S    S     + + +F++   +L  +NS VN F+YA    QF+K + ++L   RCR   P
Sbjct:   41 VLGNSLTIAAVLLDRSMRRPTNYLVASLAATDLLVGMVAIPLSLTAGDGFPRNNFLGCLTVNSLIV---SFTQVSIFGLLAISLERFVAVRFPLRYRLLCDSRCVAVTVVMT------WSCGAAVGFVPLMGWNLGPPSDGFCSFASVIDMKYMVYFIFFGCLLVPLLAVVCVY--------SYIFKVLMQRRSSRSSNAQSESAD--ERRAARSLALVVLLFAACWVPLNVLNCLSLLCGSRCSFPYELLVFAI---LLSHANSAVNPFVYAFTNTQFRKAYRRLLLCHRCRDVSP 315

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: S4RZ71 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Petromyzon marinus OX=7757 PE=3 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 8.048e-10
Identity = 82/317 (25.87%), Postives = 149/317 (47.00%), Query Frame = 3

Query:  195 AVEIPFIVF----------GNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSIL------AIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGIN------------LVSNVPYNYVTIFGFY---IVPLVIIIGLYCSTLQKLRNYQQEILTHS---SSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVP----NAIWWAMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQT 1031
            +V +P+I+           GNLLV +AV   +H+RT TN  + +LA+ D  +GAV++            +T      +N+L  +  + S+L      +IF +L + V+R+VAI  P + K+I +    +I I++       W M   IG +  +              V+ V  NY+  F F+   + PL+I+  +Y     ++R+  + I   +   + N Q   S++ L K E+K   SL +V+    + ++P    N I          +G+    L + IL  +NS+VN F+YA ++  +++ F+ ++ CR  
Sbjct:   12 SVNVPYILLELVIALLSSVGNLLVCVAVMKNRHLRTVTNYFLVSLAVADVCVGAVAI--------PCAIMTDLGLPRHNFLLCV-LMLSVLIMLTQSSIFSLLAVAVDRYVAIFNPFRYKVIMTHRNALITIVLT------WLMAFLIGLVPAMGWHKGSPSDSYCYFVAVVDMNYMVYFNFFGCVLTPLIIMFVIYARIFLQVRHQLRRIANEARGGAGNAQER-SMQSLTK-EVKTATSLFLVLFLFTVCWIPLHVLNCISLLCPGSNTPYGL---LLAAIILSHANSVVNPFLYAYRMKSYRRAFLSLIMCRDA 308

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A7SR60 (Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g128393 PE=4 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 1.868e-9
Identity = 71/271 (26.20%), Postives = 147/271 (54.24%), Query Frame = 3

Query:  213 IVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFS-ILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVN-SFGMN-IFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQIL 1016
            ++F N LVL++ F  K +RT TN  +A+LA  DFL+GA+S+P  + + L        N +  + +W   ++ + I +I+ ++ ++ +R  AI +P+K + +++R K I  + ++     + C LL  GF    N      YN + I   + +PL++++    +   K+R+ +++ +   +S+   +L      K E++   ++SI++   ++ ++P      +S+    ++  N IF++   +LQ SNS  N  +YA K P+F++ +V++L
Sbjct:   20 VIFFNGLVLVSFFKNKTLRTRTNYFIASLAWADFLVGAISIPGWLALVLTTYYGWEYNLLMLD-VWTSFDMLAGIGSIYHLMALSWDRLCAIVWPLKHR-LYTRRKYIYILCLV-----WGCALLVSGFSTIGNKADAKLYNILVIGVCFFLPLLVVLVTQGTIFVKIRHTERQHIDQQNSSHSRSL------KREVRAAKAISIMVFLFVIGWLPFFTISLLSFAAGVTYTANAIFAV--KLLQYSNSFFNPILYAQKFPEFRRAYVRML 275

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A3M6TT38 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Pocillopora damicornis OX=46731 GN=pdam_00002743 PE=3 SV=1)

HSP 1 Score: 65.855 bits (159), Expect = 2.862e-8
Identity = 76/296 (25.68%), Postives = 149/296 (50.34%), Query Frame = 3

Query:  189 AMAVEIPFI-VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFS-ILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGF----IWGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFS----LVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQTPPKSI 1046
            A  V+I F+ VFGN LV+ +   +  +RT TN  VA+LA+ D L+G VS+P+ I + L      +   ++Y     I +IF+   +I  ++ I++ERF A+ YP+       R +     +  + +++ W +          +  IN  +N+ + ++   GF+++PL++I+  Y       RN  Q     S S K+           ++++ +++++VI F ++A++P      +  +  S    I++    L    +  SNS +N  +YA+K+P+F++ F Q++ C  +   S+
Sbjct:   31 AFYVQIAFLAVFGNGLVVASFIRYSRLRTITNYFVASLAVADILVGLVSIPIWISMLLYSTGGKTLGNIYY-----ILDIFAGTCSILHLVTISLERFFAVVYPI-------RRRNTSPKVYYIFLVAVWIIPAAASLSALELREINRKANMMFLFM---GFFVIPLLVILFTYAKIWLTARNRIQPARDSSRSIKR-----------DMRIAVTIALVIGFFVIAWLPFFTVQLLIVFCESCKPRIYNTDLLLFVKYMHYSNSAINPIVYAVKIPEFRRAFKQLVCCCDSGTPSV 300

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A7SHS8 (Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g212478 PE=3 SV=1)

HSP 1 Score: 65.855 bits (159), Expect = 3.035e-8
Identity = 93/321 (28.97%), Postives = 155/321 (48.29%), Query Frame = 3

Query:  201 EIPFIVF----------GNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSIL-AIFFVLLITVERFVAIAYPMK-LKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNVPYNYVT---IFGFYIVPLVIIIGLYC-----STLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAM----------SYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQIL------RCRQTPPKSIYST 1055
            ++PF+VF          GN LV++A      +RT  N+ + +LA++D L+G  ++PL I I +L IP +S     ++ L++  +IFS L ++F +  I+VERFVA++ P+    + F   KL I I         W     I  ++ I  +SN   +YV      GF + PL II  +YC     + +  L++  +EI    +  +QS  SV    + E K+ +++SI+      A++P   +W +           +Y N+  M   +  S  +   NS VN F+YA +  + ++ F +IL      RC Q     I ST
Sbjct:   32 DLPFLVFCLLLALVIICGNSLVMVAYRANSRLRTKANLFLVSLAVSDCLVGVAALPLWILINVLRIPSSSA----FHILFISFDIFSALTSVFHLTAISVERFVAVSRPLHYASLSFRYYKLTIIIA--------WLSSALIAALYRIAQISNYMSHYVPFLLCMGF-LGPLFIIASMYCKIFNIARMLILKDPGEEIALARAQCRQSAKSVL---RRERKVAVTVSIITGLFFCAWLP---FWTVLMISFYCGPGCFYSNAAMMGTIAF-SKWMHYGNSAVNAFVYAFRDREMRRTFARILGKRCGNRCFQENVDEIPST 332

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000058027.1 (trace amine-associated receptor 13c-like [Source:NCBI gene;Acc:103033459])

HSP 1 Score: 55.4546 bits (132), Expect = 2.771e-8
Identity = 76/282 (26.95%), Postives = 133/282 (47.16%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCML----LGIGFI-----------WGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEIL-----THSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKC 1001
            VFGNLL++I+V  FK + T TN+L+ +LA++DFL+GA+ +P+ +   +    + S    F  +L +     +  +I+ V LI V+R+ A++ P      F  T       I  +V+  WC+L    LG+ +                LV +  ++ V +   ++ P  +II LY      +R +   I      T + ++K +  S++   KA   L I +   +  L   ++ + +  A++  V SF   +      IL   NS +N  IYA+  P F+KC
Sbjct:   41 VFGNLLIIISVCHFKQLHTPTNMLILSLAVSDFLVGALVIPISLIWTIETCWIFSRE--FCIYLILTSYFLTSTSIYNVALIAVDRYFALSNP------FLYTNKASVNKICFVVVCDWCVLFFYNLGVHYFNRNFKSLVMCPGDCFLVLDEIWSLVDLLFIFVFPCSVIIILYGLVFVLVRKHATAIRDLNVHTKTQTSKNATESMKSERKAAKSLGIVVCGFLACLFPYFIYSLLGKAIAVEVESFQKVL------ILVYLNSTINPVIYALFYPWFRKC 308

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000045755.1 (trace amine-associated receptor 13c-like [Source:NCBI gene;Acc:103038525])

HSP 1 Score: 54.299 bits (129), Expect = 6.772e-8
Identity = 73/299 (24.41%), Postives = 143/299 (47.83%), Query Frame = 3

Query:  177 YLAYAMAVEIPFIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIF-SILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGI--------GFIWGINLVSNVPY----------NYVTIFGFYIVPLVIIIGLYCSTLQK----LRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNILQVS-NSLVNFFIYAIKLPQFKKC 1001
            +L    A  +   VFGNLL++I+V  FK + T TN+L+ +LA++DFL+GA+ +P  +   +    +  T    Y  ++++ + F +  +IF V LI+ +R+ A++ P      F  T  +    + ++V+  W MLL          G    +++   V +          +++  F F    ++I+ GL    ++K    +R+ +     H+S+N   ++      K+E K    L I++   +   +P   ++  +  VN+  + + S  + ++ V  NS  N  IYA+  P F++C
Sbjct:   29 FLYICAAAVVLLTVFGNLLIIISVCHFKQLHTPTNMLILSLAVSDFLVGALVMPTALAWMIESCWIFDTC---YCLIYILTSYFLTTTSIFNVALISADRYFALSNP------FLYTDTVSVSTMCIVVLCNWFMLLFYNISLQYFNGHFKNLDMCPGVCFLLLDEIWSLVDFLLTFVFPCAVIIILYGLVFVLVRKHATAIRDLKVHTRDHTSANTTDSM------KSERKAAKVLGILVSVFLACLLP---YFMYTVLVNAVDIKVGSFQTVLMLVYLNSAFNPVIYALFYPWFRRC 309

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: htr2cl1 (5-hydroxytryptamine receptor 2C-like [Source:NCBI gene;Acc:103044140])

HSP 1 Score: 54.299 bits (129), Expect = 9.964e-8
Identity = 53/218 (24.31%), Postives = 101/218 (46.33%), Query Frame = 3

Query:  222 GNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPN-----------IFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGF---IWGINLVSNVPYNY-----------VTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAEL 800
            GN+LV++AV   K ++  TN  + +LA+ D L+G + +P+ +              + Y++ W +PN           +FS  +I  +  I+++R+VAI  P++     SRTK       ++ + + W + +GI     + G++    V  N+           V  F  + +PLVI++  YC T+Q L+      L  + ++ Q  L     + ++L
Sbjct:   83 GNILVILAVSLEKKLQNATNFFLRSLAVADMLVGILVMPISLIN------------ILYDYAWPLPNALCPIWIYLDVLFSTASIMHLCAISLDRYVAICNPIQHSRFNSRTK------AMLKIAAVWTISIGISMPIPVIGLSNEDKVFVNHSCVLNEERFVLVGSFVAFFIPLVIMVVTYCLTVQALQRQASVFLYETKASSQQPLQPTGPSSSQL 282

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000033638.1 (adenosine receptor A1-like [Source:NCBI gene;Acc:103040267])

HSP 1 Score: 52.7582 bits (125), Expect = 2.392e-7
Identity = 77/300 (25.67%), Postives = 136/300 (45.33%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNVPYN-------------YVTIFGFYIVPLVIIIGLYCSTLQKLR---NYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNI-LQVSNSLVNFFIYAIKLPQFKKCFVQILR----CRQTPPKSIYS 1052
            V GN+LV++ V   + +R  T   + +LAL D  +G + +PL + I L +     T  +F + L V+    SIL++   L I ++RF+ I  P +  II ++ +  + + +  ++ +   ++   G+   +N+ S  P               Y   FG  + PL I+ GLY    + +R   N + E  + SS          K    ELKL  SL++V+    L ++P  I   ++Y+  +  M   ++   I +   NS +N  +YA ++ +F+   VQI      CR   P    S
Sbjct:   32 VMGNVLVILVVALNRALRDTTFCFIVSLALADITVGVLVIPLAVVISLGLKTQFYTC-LFLSCLLVMITQTSILSL---LAIAIDRFLRIKIPTRYSIIVTQRRAWVAVGLCWLLSAITGLVPMFGWHQDVNINSTSPIECQFTSVIRMDYMVYFNFFGLVVAPLTIMTGLYIEIFRVIRRQLNRRAEATSDSS----------KYYHKELKLAKSLALVLFLFALCWLPLHIMNCITYFCPTCPMPKSAIYVGIFMSHVNSALNPLVYAFRIQRFRATLVQIAHRCVLCRAHDPSPCSS 317

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000040774.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:39634186:39635177:-1 gene:ENSAMXG00000030956.1 transcript:ENSAMXT00000040774.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.2174 bits (121), Expect = 6.744e-7
Identity = 35/121 (28.93%), Postives = 59/121 (48.76%), Query Frame = 3

Query:  177 YLAYAMAVEIPFIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWL----WVIPNIFSIL-----------AIFFVLLITVERFVAIAYP 494
            +L    A  +   VFGNLL++I++  FK + T TN+L+ +LA++DFL+GA+ +                 PV   W+    W+   +F +            +IF V LI  +R+ A++ P
Sbjct:   29 FLYICAAAVVLLTVFGNLLIIISICHFKQLHTPTNMLILSLAVSDFLVGAIVI-----------------PVSLTWMIESCWIFSAVFCVCFILVSYFLTNTSIFNVALIAFDRYFALSNP 132

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010558.1 (pep scaffold:Pmarinus_7.0:GL477661:10193:14261:1 gene:ENSPMAG00000009564.1 transcript:ENSPMAT00000010558.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.4774 bits (171), Expect = 6.184e-14
Identity = 82/317 (25.87%), Postives = 149/317 (47.00%), Query Frame = 3

Query:  195 AVEIPFIVF----------GNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSIL------AIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGIN------------LVSNVPYNYVTIFGFY---IVPLVIIIGLYCSTLQKLRNYQQEILTHS---SSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVP----NAIWWAMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQT 1031
            +V +P+I+           GNLLV +AV   +H+RT TN  + +LA+ D  +GAV++            +T      +N+L  +  + S+L      +IF +L + V+R+VAI  P + K+I +    +I I++       W M   IG +  +              V+ V  NY+  F F+   + PL+I+  +Y     ++R+  + I   +   + N Q   S++ L K E+K   SL +V+    + ++P    N I          +G+    L + IL  +NS+VN F+YA ++  +++ F+ ++ CR  
Sbjct:   12 SVNVPYILLELVIALLSSVGNLLVCVAVMKNRHLRTVTNYFLVSLAVADVCVGAVAI--------PCAIMTDLGLPRHNFLLCV-LMLSVLIMLTQSSIFSLLAVAVDRYVAIFNPFRYKVIMTHRNALITIVLT------WLMAFLIGLVPAMGWHKGSPSDSYCYFVAVVDMNYMVYFNFFGCVLTPLIIMFVIYARIFLQVRHQLRRIANEARGGAGNAQER-SMQSLTK-EVKTATSLFLVLFLFTVCWIPLHVLNCISLLCPGSNTPYGL---LLAAIILSHANSVVNPFLYAYRMKSYRRAFLSLIMCRDA 308

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006953.1 (pep scaffold:Pmarinus_7.0:GL477632:7596:14007:1 gene:ENSPMAG00000006283.1 transcript:ENSPMAT00000006953.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 45.8246 bits (107), Expect = 9.906e-6
Identity = 49/202 (24.26%), Postives = 95/202 (47.03%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIP-----------NIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNVPYNYVT-----------IFG---FYIVPLVIIIGLYCSTLQKLRNYQQEILTHS 746
            + GN+LV++AV   K ++T TN  + +LA+ D L+G + +P+ +              + Y + W +P            +FS  +I  +  I+++R++AI  P++     SRTK       ++ +++ W + +GI     +  + ++ Y Y             I+G    + +PL+I++  Y ST + LR  QQ +L   
Sbjct:   39 IAGNVLVILAVSLEKKLQTATNYFLMSLAVADMLVGILVMPISLLN------------ILYGFKWPLPLSLCPVWIYLDVLFSTASIMHLCAISLDRYIAIKKPIEHSRFNSRTK------ALLKILAVWVISVGISMPVPVLGLQDLAYVYTDGSCQMNISDFIIYGSLSSFFLPLIIMVASYVSTTRVLR--QQALLCEG 220

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO33810 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR60])

HSP 1 Score: 68.9366 bits (167), Expect = 2.583e-13
Identity = 71/271 (26.20%), Postives = 147/271 (54.24%), Query Frame = 3

Query:  213 IVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFS-ILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVN-SFGMN-IFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQIL 1016
            ++F N LVL++ F  K +RT TN  +A+LA  DFL+GA+S+P  + + L        N +  + +W   ++ + I +I+ ++ ++ +R  AI +P+K + +++R K I  + ++     + C LL  GF    N      YN + I   + +PL++++    +   K+R+ +++ +   +S+   +L      K E++   ++SI++   ++ ++P      +S+    ++  N IF++   +LQ SNS  N  +YA K P+F++ +V++L
Sbjct:   20 VIFFNGLVLVSFFKNKTLRTRTNYFIASLAWADFLVGAISIPGWLALVLTTYYGWEYNLLMLD-VWTSFDMLAGIGSIYHLMALSWDRLCAIVWPLKHR-LYTRRKYIYILCLV-----WGCALLVSGFSTIGNKADAKLYNILVIGVCFFLPLLVVLVTQGTIFVKIRHTERQHIDQQNSSHSRSL------KREVRAAKAISIMVFLFVIGWLPFFTISLLSFAAGVTYTANAIFAV--KLLQYSNSFFNPILYAQKFPEFRRAYVRML 275

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO36788 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHS8])

HSP 1 Score: 65.855 bits (159), Expect = 4.197e-12
Identity = 93/321 (28.97%), Postives = 155/321 (48.29%), Query Frame = 3

Query:  201 EIPFIVF----------GNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSIL-AIFFVLLITVERFVAIAYPMK-LKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNVPYNYVT---IFGFYIVPLVIIIGLYC-----STLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAM----------SYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQIL------RCRQTPPKSIYST 1055
            ++PF+VF          GN LV++A      +RT  N+ + +LA++D L+G  ++PL I I +L IP +S     ++ L++  +IFS L ++F +  I+VERFVA++ P+    + F   KL I I         W     I  ++ I  +SN   +YV      GF + PL II  +YC     + +  L++  +EI    +  +QS  SV    + E K+ +++SI+      A++P   +W +           +Y N+  M   +  S  +   NS VN F+YA +  + ++ F +IL      RC Q     I ST
Sbjct:   32 DLPFLVFCLLLALVIICGNSLVMVAYRANSRLRTKANLFLVSLAVSDCLVGVAALPLWILINVLRIPSSSA----FHILFISFDIFSALTSVFHLTAISVERFVAVSRPLHYASLSFRYYKLTIIIA--------WLSSALIAALYRIAQISNYMSHYVPFLLCMGF-LGPLFIIASMYCKIFNIARMLILKDPGEEIALARAQCRQSAKSVL---RRERKVAVTVSIITGLFFCAWLP---FWTVLMISFYCGPGCFYSNAAMMGTIAF-SKWMHYGNSAVNAFVYAFRDREMRRTFARILGKRCGNRCFQENVDEIPST 332

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO36649 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI22])

HSP 1 Score: 60.077 bits (144), Expect = 3.396e-10
Identity = 37/111 (33.33%), Postives = 63/111 (56.76%), Query Frame = 3

Query:  198 VEIPFIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKL 530
            V IPF VF N LV++A+  + HMR+ +N LV  LA+ D L G V+ PL + + L+    + T  V     + +   F   ++  V+LI +ER++AI  P++   I ++ ++
Sbjct:   49 VSIPFTVFANALVILALLRYPHMRSTSNTLVGWLAVADGLCGLVAQPLFVCVTLMYGMTSVTRCVMEELTFSVIRTFYGTSLLHVMLINIERYIAITRPLRYPSIVTKERV 159

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO29285 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T427])

HSP 1 Score: 58.9214 bits (141), Expect = 5.770e-10
Identity = 77/293 (26.28%), Postives = 137/293 (46.76%), Query Frame = 3

Query:  210 FIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAI----FFVLLITV------------ERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLG-IGFIWGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAE-LKXXXXXXXXXXXXXXAYVP----NAIWWAMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRC 1022
            F V GN +VL+A+F +  +RT +N+ +A+LAL D+++GA++                 NP FY  L ++ +I  I  I     FV L+TV            +RF+A++ PM  + + +  + ++ I +      F+  LLG   F+   + +S V      I GF  +P V+I   Y   +   +    +I      N Q     E  N+ +  K   +  IVIV  ++ Y+P    N I    S   + F +N     ++++  S+S +N ++YAI++ +F+    ++L C
Sbjct:    2 FSVGGNTIVLLAIFKYSSLRTTSNMFIASLALADWIVGALA-----------------NP-FYVSLSLMKSIRDIREIKNTETFVWLLTVAATQYNLCAVSIDRFIAVSKPMHYRQVVTVPRCLVVIALTW----FFAALLGSSAFLVPYDQISGVWIAGSVITGF--IPAVVISFCYSQIVIAAKTQTNKINEAQPRNSQQQTIEETRNRLKNRKAAWTFGIVIVLFVVLYLPSLVTNFITLGASTQCDFFDINRLWFWTSMICYSSSAINPWVYAIRMREFRTSVKRLLTC 270

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO35738 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKN7])

HSP 1 Score: 58.5362 bits (140), Expect = 8.344e-10
Identity = 77/293 (26.28%), Postives = 137/293 (46.76%), Query Frame = 3

Query:  210 FIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAI----FFVLLITV------------ERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLG-IGFIWGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAE-LKXXXXXXXXXXXXXXAYVP----NAIWWAMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRC 1022
            F V GN +VL+A+F +  +RT +N+ +A+LAL D+++GA++                 NP FY  L ++ +I  I  I     FV L+TV            +RF+A++ PM  + + +  + ++ I +      F+  LLG   F+   + +S V      I GF  +P V+I   Y   +   +    +I      N Q     E  N+ +  K   +  IVIV  ++ Y+P    N I    S   + F +N     ++++  S+S +N ++YAI++ +F+    ++L C
Sbjct:   27 FSVGGNTIVLLAIFKYSSLRTTSNMFIASLALADWIVGALA-----------------NP-FYVSLSLMKSIRDIREIKNTETFVWLLTVAATQYNLCAVSIDRFIAVSKPMHYRQVVTVPRCLVVIALTW----FFAALLGSSAFLVPYDQISGVWIAGSVITGF--IPAVVISFCYSQIVIAAKTQTNKINEAQPRNSQQQTIEETRNRLKNRKAAWTFGIVIVLFVVLYLPSLVTNFITLGASTQCDFFDINRLWFWTSMICYSSSAINPWVYAIRMREFRTSVKRLLTC 295

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000002753.2 (beta-2 adrenergic receptor [Source:NCBI gene;Acc:101159524])

HSP 1 Score: 55.4546 bits (132), Expect = 4.205e-8
Identity = 36/125 (28.80%), Postives = 68/125 (54.40%), Query Frame = 3

Query:  180 LAYAMAVEIPFIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNW--------LWVIPNIFSILA-IFFVLLITVERFVAIAYPMKLKIIFSRTK 527
            LA AMA+ +  IVFGN++V+ A+  F  ++T TN+ +A+LA+ D ++G V V           P +S+N +  +W         W   ++  + A I  + +I ++R++AI  P++   + +R +
Sbjct:   28 LAVAMAILVLAIVFGNVMVISAILRFHRLQTVTNLFIASLAVADLIMGVVVV-----------PFSSSNILLRSWKFGNFMCEFWTAADVLCVTASIETLCVIALDRYLAITLPLRYPTLLTRAR 141

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000019540.2 (trace amine-associated receptor 1-like [Source:NCBI gene;Acc:101174969])

HSP 1 Score: 52.7582 bits (125), Expect = 2.072e-7
Identity = 79/277 (28.52%), Postives = 133/277 (48.01%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXS-FWCMLLGIGFIWGINLVSNV----PYNYVT-----IFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKCFVQIL 1016
            V GNLLV+ +V  F+ + T TN L+ +LA+ D L+GAV +PL +   +       +  VF      +  I    +I  +  I+V+R+ A+  P+       R K+  ++I I+I+IS F   L  +GF  G N  + V     +  VT     +F FY+ PL++++ LY       +     +  H+ S        E  NK E K T +L++++   +L ++P+     +  +  S        + N L +SNSL+N FIYA     F+  F+ I+
Sbjct:   46 VCGNLLVITSVVYFRQLHTPTNALILSLAVADLLVGAVVLPLTMKFSVSTCLYNRS--VFCLIRSSLDMILGSCSILNLCCISVDRYYAVCQPLTY-----RFKINNHVIGIMILISWFLPALFAVGFQLGFNRANCVQRCLSFALVTQFISFVFLFYL-PLILMLCLYLKIFLVAQKQANSLQKHTKSR-------ENANKLEKKATKTLAVIMGVFLLCWLPSFFCITIVSFSRSSDTGPLIEILNWLALSNSLLNPFIYAFFYSWFRSAFLLII 307

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: htr2cl1 (5-hydroxytryptamine receptor 2C-like [Source:NCBI gene;Acc:101165845])

HSP 1 Score: 53.1434 bits (126), Expect = 2.245e-7
Identity = 49/216 (22.69%), Postives = 100/216 (46.30%), Query Frame = 3

Query:  204 IPFIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPN-----------IFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIG--------------FIWGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSV 776
            I   + GN+LV++AV   K ++  TN  + +LA+ D L+G + +P+ +              + Y++ W +P+           +FS  +I  +  I+++R+VAI  P++     SRTK       ++ + + W + +G+               F+ G  +++   +  +  F  + +PLVI++  YC T+Q L+      L  + ++ Q  L+ 
Sbjct:   85 IALTIGGNILVILAVSLEKKLQNATNFFLRSLAVADMLVGILVMPISLIN------------ILYDYAWPLPSALCPIWIYLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTK------AMMKIAAVWTISIGVSMPIPVIGLLNEDKVFVDGSCVLNEERFMLIGSFVAFFIPLVIMVVTYCLTIQVLQRQATVFLCEAKTSSQQPLNT 282

[Close]

Query:  204 IPFIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLWVIPN-----------IFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCMLLGIG--------------FIWGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSV 776
            I   + GN+LV++AV   K ++  TN  + +LA+ D L+G + +P+ +              + Y++ W +P+           +FS  +I  +  I+++R+VAI  P++     SRTK       ++ + + W + +G+               F+ G  +++   +  +  F  + +PLVI++  YC T+Q L+      L  + ++ Q  L+ 
Sbjct:   85 IALTIGGNILVILAVSLEKKLQNATNFFLRSLAVADMLVGILVMPISLIN------------ILYDYAWPLPSALCPIWIYLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTK------AMMKIAAVWTISIGVSMPIPVIGLLNEDKVFVDGSCVLNEERFMLIGSFVAFFIPLVIMVVTYCLTIQVLQRQATVFLCEAKTSSQQPLNT 282

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000006865.2 (alpha-1A adrenergic receptor [Source:NCBI gene;Acc:101159926])

HSP 1 Score: 50.0618 bits (118), Expect = 2.547e-6
Identity = 49/229 (21.40%), Postives = 108/229 (47.16%), Query Frame = 3

Query:  180 LAYAMAVEIPFIVFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNW--------LWVIPNIFSILA-IFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCM--LLGIGFIWGIN----------LVSNVP-YNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAEL 800
            LA  +   I F + GN+LV+++V   +H+RT TN  +  LA+ D L+G             ++P+++T  +   W        +W   ++    A I  + +I+++R++ +++P++   I +  +       ++ ++  W +  ++ IG + G            L++  P Y   +  G + +PL +I+ +YC      R Y   +   ++ N ++ +  E++N +EL
Sbjct:   50 LALVLGAFIVFAIAGNILVILSVVCNRHLRTPTNYFIINLAMADLLLGTT-----------VLPVSATKEILNYWVFGRIFCDIWAALDVLCCTASIMSLCVISIDRYIGVSHPLQYPGIVTEKR------ALLAMLGVWVLSVVISIGPLLGWKQPPSDDDMECLITEEPFYALFSSLGSFYIPLAVILAMYC------RVYI--VAKRTTRNLEAGVMRERMNTSEL 253

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000016325.1 (SMESG000016325.1)

HSP 1 Score: 50.0618 bits (118), Expect = 1.688e-6
Identity = 75/323 (23.22%), Postives = 134/323 (41.49%), Query Frame = 3

Query:  222 GNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNP---VFYNWLWVIPNIFSILAIFFVLLITVERFVAIAYPMK-LKIIFSRTKLXXXXXXXXXXXSFWCMLLGIGFIWGINLVSNVP-------------------------------------YNYVTIFG----------FYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFS---LVSNILQVSNSLVNFFIYAIKLPQFKKCFVQILRCRQ 1028
            GNLLV++ +     MR  TNIL+ +LA+ D L     VP    +Y+     T   P   V       +  I +  +++ ++L++++R++A+ +P++ + +  SR  +                 + +G +W + LVSN+P                                     Y    +FG          FY+ P++II  LY   + +L   +   ++HS+    +   V K+          + +VIV   L + P    + +  Y    G N+F    ++SN L  SNS+VN F+YA     F++ F  +L CR+
Sbjct:   53 GNLLVIVVIIANIQMRNTTNILIISLAVADLLFIIFCVPFTAVMYV-----TGGWPLGRVLCQIYQYMTYITAYCSVYTLVLMSIDRYLAVVHPIRSMTLRNSRNTI-----------------IAVGTVWSLFLVSNLPLLINSDIIEGPRDEITDCLVDYCTYKPFMKWNSTKKRYEDDKVFGKIYYTLFFVMFYLWPVIIISVLYGFLIYRLLCGRSSKISHSNDAMVTKKRVTKM----------VIVVIVIFTLCWAPIQTIFIIQLYGKDPGGNLFRTIHVISNCLAYSNSMVNPFLYAFLSENFRRAFANLLCCRR 343

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000074489.1 (SMESG000074489.1)

HSP 1 Score: 47.7506 bits (112), Expect = 9.127e-6
Identity = 74/316 (23.42%), Postives = 138/316 (43.67%), Query Frame = 3

Query:  216 VFGNLLVLIAVFGFKHMRTNTNILVATLALNDFLIGAVSVXXXXXXXXXXXXXTSTNPVFYNWLW---------VIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLXXXXXXXXXXXSFWCM--LLGIG------------FIWGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCSTLQKLRNYQQEILTHSSSNKQSNLSVEKLN--KAELKXXXXXXXXXXXXXXAYVPNAIWWAMSYYVNSFGMNIFSLVSNIL-QVSNSLVNFFIYAIKLPQFK----KCFVQILRCRQTPPKSIYSTTITAVT 1073
            V GNLLVL      K +RT  N+ + +LA+ D    AV+          ++ ++S N     W W          I  +F  ++I  + LI+++R+  IA P +     +  + II ++ + +    W      G G            F +      N+ +N     G +I+P+ III  Y   ++ +R ++ E+L  +     S+ +  K    KA+++      I++   +L++ P AI   M+       +N ++    +L   ++++ N FIYAI  P+F+    K F  ++ C    PK   +T+  + T
Sbjct:   69 VLGNLLVLYIFASAKSLRTPPNMFIMSLAIGDLTFSAVN-------GFPLLTISSFN---TRWAWGKLTCEIYGFIGGLFGFISINTMALISLDRYFVIAQPFQTMKSLTIKRAIIMLVFVWLYSLIWSTPPFFGYGNYVPEGFQTSCTFDYLTQSKGNIIFNIGMYIGNFIIPVGIIIFCYYQIVKAVRVHELEMLKMAQKMNASHPTSMKTGAKKADVQAAKISVIIVFLYMLSWTPYAIIALMALTGRRDHLNPYTAELPVLFAKTSAMYNPFIYAINHPKFRIQLEKKFPCLICCCPPKPKERDTTSAASAT 374

The following BLAST results are available for this feature:

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TRHR	3.819e-7	21.38	thyrotropin releasing hormone receptor [Source:HGN...	[more]
TRHR	3.819e-7	21.38	thyrotropin releasing hormone receptor [Source:HGN...	[more]
TAAR9	2.051e-6	30.00	trace amine associated receptor 9 (gene/pseudogene...	[more]
HTR2C	4.485e-6	27.15	5-hydroxytryptamine receptor 2C [Source:HGNC Symbo...	[more]
HTR2C	4.485e-6	27.15	5-hydroxytryptamine receptor 2C [Source:HGNC Symbo...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ador-1	1.078e-8	25.98	ADenOsine Receptor homolog [Source:UniProtKB/TrEM...	[more]
ador-1	1.101e-8	25.98	ADenOsine Receptor homolog [Source:UniProtKB/TrEM...	[more]
ser-5	1.873e-6	30.70	SERotonin/octopamine receptor family [Source:UniP...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
taar20r	4.769e-7	26.64	trace amine associated receptor 20r [Source:ZFIN;A...	[more]
taar20g	1.196e-6	28.08	trace amine associated receptor 20g [Source:ZFIN;A...	[more]
CR925820.11	1.910e-6	26.62	trace amine associated receptor 20r [Source:NCBI g...	[more]
taar20q	3.821e-6	26.28	trace amine associated receptor 20q [Source:ZFIN;A...	[more]
taar20w	4.723e-6	33.62	trace amine associated receptor 20w [Source:ZFIN;A...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HTR2C	1.434e-7	25.46	5-hydroxytryptamine (serotonin) receptor 2C, G pro...	[more]
HTR2C	1.988e-7	25.58	5-hydroxytryptamine (serotonin) receptor 2C, G pro...	[more]
ENSXETT00000006865.1	7.310e-7	25.16	pep primary_assembly:Xenopus_tropicalis_v9.1:3:118...	[more]
ENSXETT00000006856.1	1.204e-6	25.16	pep primary_assembly:Xenopus_tropicalis_v9.1:3:118...	[more]
phactr1	3.327e-6	34.91	phosphatase and actin regulator 1 [Source:Xenbase;...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Taar9	6.287e-7	30.69	trace amine-associated receptor 9 [Source:MGI Symb...	[more]
Trhr	2.221e-6	21.07	thyrotropin releasing hormone receptor [Source:MGI...	[more]
Trhr	2.221e-6	21.07	thyrotropin releasing hormone receptor [Source:MGI...	[more]
Trhr	2.221e-6	21.07	thyrotropin releasing hormone receptor [Source:MGI...	[more]
Adra1a	8.444e-6	22.75	adrenergic receptor, alpha 1a [Source:MGI Symbol;A...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q5IS66\|5HT2C_PANTR	3.263e-7	27.43	5-hydroxytryptamine receptor 2C OS=Pan troglodytes...	[more]
sp\|P34981\|TRFR_HUMAN	1.834e-6	21.38	Thyrotropin-releasing hormone receptor OS=Homo sap...	[more]
sp\|Q5QD04\|TAAR9_MOUSE	4.398e-6	30.69	Trace amine-associated receptor 9 OS=Mus musculus ...	[more]
sp\|Q923Y6\|TAAR9_RAT	8.204e-6	32.35	Trace amine-associated receptor 9 OS=Rattus norveg...	[more]
sp\|O46639\|TRFR_BOVIN	9.449e-6	22.47	Thyrotropin-releasing hormone receptor OS=Bos taur...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8JHW7	2.073e-10	25.93	G_PROTEIN_RECEP_F1_2 domain-containing protein OS=...	[more]
S4RZ71	8.048e-10	25.87	G_PROTEIN_RECEP_F1_2 domain-containing protein OS=...	[more]
A7SR60	1.868e-9	26.20	Predicted protein (Fragment) OS=Nematostella vecte...	[more]
A0A3M6TT38	2.862e-8	25.68	G_PROTEIN_RECEP_F1_2 domain-containing protein OS=...	[more]
A7SHS8	3.035e-8	28.97	Predicted protein OS=Nematostella vectensis OX=453...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000058027.1	2.771e-8	26.95	trace amine-associated receptor 13c-like [Source:N...	[more]
ENSAMXT00000045755.1	6.772e-8	24.41	trace amine-associated receptor 13c-like [Source:N...	[more]
htr2cl1	9.964e-8	24.31	5-hydroxytryptamine receptor 2C-like [Source:NCBI ...	[more]
ENSAMXT00000033638.1	2.392e-7	25.67	adenosine receptor A1-like [Source:NCBI gene;Acc:1...	[more]
ENSAMXT00000040774.1	6.744e-7	28.93	pep primary_assembly:Astyanax_mexicanus-2.0:3:3963...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000010558.1	6.184e-14	25.87	pep scaffold:Pmarinus_7.0:GL477661:10193:14261:1 g...	[more]
ENSPMAT00000006953.1	9.906e-6	24.26	pep scaffold:Pmarinus_7.0:GL477632:7596:14007:1 ge...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO33810	2.583e-13	26.20	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36788	4.197e-12	28.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36649	3.396e-10	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29285	5.770e-10	26.28	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35738	8.344e-10	26.28	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000002753.2	4.205e-8	28.80	beta-2 adrenergic receptor [Source:NCBI gene;Acc:1...	[more]
ENSORLT00000019540.2	2.072e-7	28.52	trace amine-associated receptor 1-like [Source:NCB...	[more]
htr2cl1	2.245e-7	22.69	5-hydroxytryptamine receptor 2C-like [Source:NCBI ...	[more]
htr2cl1	2.245e-7	22.69	5-hydroxytryptamine receptor 2C-like [Source:NCBI ...	[more]
ENSORLT00000006865.2	2.547e-6	21.40	alpha-1A adrenergic receptor [Source:NCBI gene;Acc...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000016325.1	1.688e-6	23.22	SMESG000016325.1	[more]
SMESG000074489.1	9.127e-6	23.42	SMESG000074489.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034274 ID=SMED30034274|Name=G_PROTEIN_RECEP_F1_2 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1087bp
ATTGACGAGATAAATTAAAGAAATTCATTTAAAAAGCGATTTAACGAATT
AAAAGAAAAGAAAATTCCACCAATCAGGTACTCCTTTTTCATTTGTATTA
AATGAGTTTTTTGGTAATTTTCCCATTAAATATAATCATGAACTCCTCGA
GCAACAGTACGGACGATTCGAATGCCTACTTGGCCTACGCCATGGCCGTT
GAGATTCCTTTTATCGTTTTTGGAAACTTGTTGGTTTTGATTGCAGTTTT
CGGATTTAAACATATGAGAACGAATACAAATATTTTAGTGGCAACTTTGG
CTTTGAATGACTTCTTAATTGGTGCAGTTTCTGTGCCGCTTATGATTTAT
ATTTACTTATTAATTATCCCCCTAACAAGTACTAATCCTGTGTTTTACAA
CTGGCTTTGGGTAATCCCGAACATATTTTCGATTTTAGCGATATTTTTCG
TGCTACTAATCACGGTTGAAAGATTTGTCGCTATTGCTTATCCAATGAAG
CTGAAAATTATTTTCAGTCGCACTAAATTAATTATTTATATAATCATAAT
AGTTATTGTTATTTCTTTCTGGTGTATGTTGTTGGGGATCGGATTTATTT
GGGGGATAAATTTAGTGAGTAATGTCCCATATAACTATGTAACAATTTTC
GGGTTTTACATTGTGCCGTTGGTCATTATTATTGGTTTGTATTGTTCGAC
ACTGCAAAAATTGAGGAATTATCAACAGGAAATCCTCACTCATAGCAGTT
CGAATAAACAATCAAATCTGTCTGTGGAAAAACTAAATAAAGCGGAACTG
AAATTAACAATTTCATTGAGTATTGTTATTGTTTTCCTAATTCTGGCGTA
CGTTCCGAATGCGATTTGGTGGGCCATGAGTTACTATGTCAATTCATTCG
GAATGAATATATTTTCATTGGTATCCAATATTTTACAGGTTTCTAATTCT
TTGGTCAATTTCTTCATTTATGCTATCAAACTTCCACAATTTAAGAAGTG
TTTTGTTCAAATTCTCAGGTGCAGACAAACTCCGCCTAAGTCGATTTATT
CAACAACAATAACGGCAGTTACACTTGCATAGGAGAC

protein sequence of SMED30034274-orf-1

>SMED30034274-orf-1 ID=SMED30034274-orf-1|Name=SMED30034274-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=327bp
MSFLVIFPLNIIMNSSSNSTDDSNAYLAYAMAVEIPFIVFGNLLVLIAVF
GFKHMRTNTNILVATLALNDFLIGAVSVPLMIYIYLLIIPLTSTNPVFYN
WLWVIPNIFSILAIFFVLLITVERFVAIAYPMKLKIIFSRTKLIIYIIII
VIVISFWCMLLGIGFIWGINLVSNVPYNYVTIFGFYIVPLVIIIGLYCST
LQKLRNYQQEILTHSSSNKQSNLSVEKLNKAELKLTISLSIVIVFLILAY
VPNAIWWAMSYYVNSFGMNIFSLVSNILQVSNSLVNFFIYAIKLPQFKKC
FVQILRCRQTPPKSIYSTTITAVTLA*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR000276	GPCR_Rhodpsn
IPR017452	GPCR_Rhodpsn_7TM

Vocabulary: **molecular function**
Term	Definition
GO:0004930	G-protein coupled receptor activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000276	G protein-coupled receptor, rhodopsin-like	PRINTS	PR00237	GPCRRHODOPSN	coord: 272..298 score: 25.54 coord: 106..128 score: 22.59 coord: 178..201 score: 21.12 coord: 26..50 score: 25.08 coord: 59..80 score: 27.96
IPR000276	G protein-coupled receptor, rhodopsin-like	SMART	SM01381	7TM_GPCR_Srsx_2	coord: 35..305 e-value: 0.0049 score: -64.9
IPR000276	G protein-coupled receptor, rhodopsin-like	PFAM	PF00001	7tm_1	coord: 41..290 e-value: 3.5E-21 score: 75.7
IPR000276	G protein-coupled receptor, rhodopsin-like	PROSITE	PS00237	G_PROTEIN_RECEP_F1_1	coord: 112..128
None	No IPR available	GENE3D	G3DSA:1.20.1070.10		coord: 13..312 e-value: 3.8E-42 score: 146.3
None	No IPR available	PANTHER	PTHR24246	OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR	coord: 19..310
None	No IPR available	CDD	cd00637	7tm_classA_rhodopsin-like	coord: 30..292 e-value: 3.2725E-24 score: 97.7334
None	No IPR available	SUPERFAMILY	SSF81321	Family A G protein-coupled receptor-like	coord: 16..317
None	No IPR available	TMHMM	TMhelix		coord: 28..50
None	No IPR available	TMHMM	TMhelix		coord: 175..197
None	No IPR available	TMHMM	TMhelix		coord: 143..165
None	No IPR available	TMHMM	TMhelix		coord: 71..93
None	No IPR available	TMHMM	TMhelix		coord: 103..122
None	No IPR available	TMHMM	TMhelix		coord: 269..291
None	No IPR available	TMHMM	TMhelix		coord: 237..259
IPR017452	GPCR, rhodopsin-like, 7TM	PROSITE	PS50262	G_PROTEIN_RECEP_F1_2	coord: 41..290 score: 25.186

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G_PROTEIN_RECEP_F1_2 domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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