CRAL-TRIO domain-containing protein

Overview


Name	CRAL-TRIO domain-containing protein
Smed ID	SMED30034257
Length (bp)	1138

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of CRAL-TRIO domain-containing protein (SMED30034257) t-SNE clustered cells

Violin plots show distribution of expression levels for CRAL-TRIO domain-containing protein (SMED30034257) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of CRAL-TRIO domain-containing protein (SMED30034257) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for CRAL-TRIO domain-containing protein (SMED30034257) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034257

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
epidermis	SMED30034257	SMESG000009988.1	dd_Smed_v4_3680_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30034257	SMESG000009988.1	dd_Smed_v4_3680_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034257	SMESG000009991.1 SMESG000009990.1 SMESG000009988.1	Contig50444	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034257	SMESG000009991.1 SMESG000009990.1 SMESG000009988.1	Contig50444	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034257	SMESG000009988.1	Contig55003	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034257	SMESG000009988.1	Contig55003	newmark_ests	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30034257	SMESG000009988.1	SMED30034257	smed_20140614	PMID:26457503 Tu et al., 2015
Category 3 cell	SMED30034257	SMESG000009988.1	dd_Smed_v6_3680_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30034257	SMESG000009988.1	dd_Smed_v4_3680_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
Category 3 cell	SMED30034257	SMESG000009988.1	dd_Smed_v4_3680_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
neoblast	SMED30034257	SMESG000009988.1	SMED_00966_V2_1r	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034257	SMESG000009988.1	SMED_00966_V2_1r	GPL14150	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Match: TTPAL (alpha tocopherol transfer protein like [Source:HGNC Symbol;Acc:HGNC:16114])

HSP 1 Score: 93.5893 bits (231), Expect = 1.024e-20
Identity = 70/250 (28.00%), Postives = 117/250 (46.80%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEA 921
            A  EL E P+     +++ R  V K  P+L+   D  FLL FLR  KFD+ +A + L N+ + R   R  PE F   ++  +  +    +  +  L  T   G  +     + W P   PI + ++ ++++LE  +Q++  Q+ G+    D  G   S       P + K +  + QD +PIR K   +  EP  +   + I++ FL EK   R F    D+      +P   ++LP+EYGG   ++D A
Sbjct:   43 AREELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCR---RSWPEVFN--NLKPSALKDVLASGFLTVLPHTDPRGCHVVCIRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RSILPKEYGGTAGELDTA 284

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Query:  178 ALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEA 921
            A  EL E P+     +++ R  V K  P+L+   D  FLL FLR  KFD+ +A + L N+ + R   R  PE F   ++  +  +    +  +  L  T   G  +     + W P   PI + ++ ++++LE  +Q++  Q+ G+    D  G   S       P + K +  + QD +PIR K   +  EP  +   + I++ FL EK   R F    D+      +P   ++LP+EYGG   ++D A
Sbjct:   43 AREELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCR---RSWPEVFN--NLKPSALKDVLASGFLTVLPHTDPRGCHVVCIRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RSILPKEYGGTAGELDTA 284

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Match: CLVS2 (clavesin 2 [Source:HGNC Symbol;Acc:HGNC:23046])

HSP 1 Score: 86.2705 bits (212), Expect = 2.950e-18
Identity = 80/310 (25.81%), Postives = 137/310 (44.19%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQT----KQMIPLG-----RTVD--GETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDF-YTKGSPWANISVDESKRPVETLK 1023
            T+   GL+    + A  ELNE+P  ++  I+  R  V + P +    TD  F+L FLR  KF H +A + L              +YF++   N  +F+ F  T    KQ +  G       +D  G  +    +  W+     +  +++ + +SLE  +++  LQ+ G    +D      +F +A    P +++      QD +P RF G     +P +    Y ++  FL EK RKR+F    ++    + I     +LP E+GG  P  D  +  WA+ + D  Y   S +   +VD    PV+ ++
Sbjct:    2 THLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLL-------------AQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNF--TFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIH--PEILPSEFGGMLPPYD--MGTWARTLLDHEYDDDSEY---NVDSYSMPVKEVE 289

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Match: CLVS1 (clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139])

HSP 1 Score: 85.8853 bits (211), Expect = 5.019e-18
Identity = 77/296 (26.01%), Postives = 126/296 (42.57%), Query Frame = 1

Query:  103 LQTFKQSKMADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDG-------------ETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            L T+       T+   GL+    + A  ELNE+P  ++  I+  R  + + P +    TD  F+L FLR  KF  A A + L              +YFQ+  +N  +F+ F      I     +DG             + L    +N W+        +++ + +SLEV +++  LQI G    +D      SF +A    P ++K      QD +P RF G     +P +    Y +++ FL +K RKR+F    ++    + I      LP E+GG  P  D  +  WA+ +
Sbjct:   13 LNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLL-------------AQYFQYRQLNLDMFKNFKADDPGIKRA-LIDGFPGVLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNF--SFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIH--PEFLPSEFGGTLPPYD--MGTWARTL 287

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Query:  103 LQTFKQSKMADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDG-------------ETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            L T+       T+   GL+    + A  ELNE+P  ++  I+  R  + + P +    TD  F+L FLR  KF  A A + L              +YFQ+  +N  +F+ F      I     +DG             + L    +N W+        +++ + +SLEV +++  LQI G    +D      SF +A    P ++K      QD +P RF G     +P +    Y +++ FL +K RKR+F    ++    + I      LP E+GG  P  D  +  WA+ +
Sbjct:   13 LNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLL-------------AQYFQYRQLNLDMFKNFKADDPGIKRA-LIDGFPGVLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNF--SFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIH--PEFLPSEFGGTLPPYD--MGTWARTL 287

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG33514 (gene:FBgn0053514 transcript:FBtr0091456)

HSP 1 Score: 119.398 bits (298), Expect = 1.397e-30
Identity = 88/323 (27.24%), Postives = 163/323 (50.46%), Query Frame = 1

Query:  154 LTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKK--LMQVMFMSLEVQ----LQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGK-GPKMD--EAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFDA 1095
            LT   ++VA  +L EDP+++ A +++F+ W++  PHLN   D +FL+ FLR  K+   +A+ +LD + T+++    +P+YF+  +  D+ F +  QT  +I L   ++      G+   W    +P++K  +++ M ++  +Q    L++ Y  + G+   MDM G   + +  ++ P + K  T   ++  P+R K Q        +   +N+ +  +++K + R+F     +    E+IP     LPEEYGG+ G   D   A++K   E  DF+ +     N   DES RP + +       D+ G   G +G+F K + 
Sbjct:    8 LTPELQKVAKEQLKEDPERLEADLQAFKTWIEQQPHLNPRMDDQFLVAFLRGCKYSLERAKSKLDKYYTLKTK---YPDYFRVTNTTDSKFREIHQTGAIIYLPTPLNENGPRIGI---WRMGLVPVEKYTMLECMQVAQAMQEIAILEDDYANVNGVVFIMDMKGATAAHLFQMT-PSMAKKFTVFSEEALPLRLKAQHFINTITGFEQLFNMFKPMMSKKMQSRLFVHGNKMGLLTEQIP--LKYLPEEYGGENGTTQDIVAAMEKKLDEYADFFQEN---VNFGTDESLRPGKPI-------DFEG-LFGVEGSFRKLNV 310

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG12926 (gene:FBgn0033437 transcript:FBtr0088502)

HSP 1 Score: 100.523 bits (249), Expect = 9.997e-24
Identity = 83/315 (26.35%), Postives = 139/315 (44.13%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQM-----IPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQL-QNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV---RDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESL-GTKGTFTKFD 1092
            A  EL E P +++  IE+ R W+   PHL    D++FL+ FLR  K+   K + +LDNF  +R +    PE ++    N  V EK            +P     DG  +       ++ K+  I +++QV  M  E+Q+ ++    I G    +DM G G   +    D  ++K +  +    YP R KG      P     F +I +  ++EK RKR F I   +   ++ +P  +  LP EYGG    + + +  W  ++   + F+ + + +         +PV            + ESL G +G+F K D
Sbjct:   20 AHDELGEIPDRIDEDIETLRTWISKQPHLKARQDAQFLVAFLRGCKYSLEKTKLKLDNFYAMRGAV---PELYK----NRIVGEKQLSILDTGCLLRLPQPLQADGPRIHISRYGQYDSKKYSIAEVVQVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHLFQF-DAVLVKKLAVLGDKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKR-FHIHSKLDSLYKYVP--KECLPAEYGGSNGTIQDVVSTWRTKLLAYKPFFEEEASYGTNEKLRRGQPV------------SAESLFGIEGSFRKLD 311

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG33966 (gene:FBgn0053966 transcript:FBtr0100007)

HSP 1 Score: 98.9821 bits (245), Expect = 4.219e-23
Identity = 73/318 (22.96%), Postives = 149/318 (46.86%), Query Frame = 1

Query:  154 LTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDIN-DAVFEKF-FQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIY-GMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESL-GTKGTFTKFDA 1095
            L+   ++ A+  LNE P +++  I + R W+K  PHL   TD +FL+ FLR  KF   + + ++D F T+R+    +PE++   +++ D   E F   T  ++P     +G  L       ++P +  ++++ +   +  ++ L    + I  G+ + +D+          +S P   K MT   ++  P+R +G      P  +   +N+++  +++K + R++      +  + +IP  +  LP EYGG+   + E + +W + +  +        N   DES R  + + +         ESL G +G+F + + 
Sbjct:    7 LSPELQKTAIENLNEVPNKLDDDIAALRDWIKQQPHLKARTDDQFLVNFLRGCKFSLERTKSKIDRFYTLRTK---YPEFYLGHNVDVDKALEIFRLGTIVILPRPLNDNGPRLALLRMACYDPSKYTLQEVNRAAGLMQQIMLDEDDVAIVNGLISILDLSNVTTGHFLQMS-PSFAKKMTVFQEEALPLRPQGIHFINTPNGFDTIFNMIKPMMSKKQQGRLYVHGSKWEALYNQIP--KQYLPVEYGGENGSIPELLQQWEQRILAYRNYWEEEKNYGTDESLRVGQPVDF---------ESLFGLQGSFRQLNV 309

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG10657 (gene:FBgn0036289 transcript:FBtr0075975)

HSP 1 Score: 97.8265 bits (242), Expect = 1.179e-22
Identity = 76/260 (29.23%), Postives = 127/260 (48.85%), Query Frame = 1

Query:  151 GLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHL-NCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPL-GRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFME--AVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKE-DIQKGFEKIPGLEALLPEEYGGKGPKMD 915
            GL+   K VA  EL+ED       +  FR W++  PH+  C TD+ FLL FLR  KF    A + L+ + T+R   +  P++F+  DIND    + F+   ++PL  R   G  + F V+  ++P +    ++ +V  +  E  L ++  Q+ G     D  G    F+   +++D   ++++ +  Q+  P+R K       P + +    +    L++K +KR+   K  DI K   KI    A+LP+EYGG  P  D
Sbjct:   30 GLSPAMKLVAKEELHEDENIRRQALAQFREWIEKHPHIRKCRTDTVFLLRFLRTKKFSVPSACEMLERYLTIR---QLFPQWFKQLDINDPAINEIFENGYLVPLPQRDSTGRQVIFSVAAKFDPYKFTSVQMARVHSLVCEALLDDEDSQVAGYVYINDESGMNMGFVSLWSLTD---LRSIVKCIQNSTPMRHKETHFVNIPHYANRIIELGVSMLSDKLKKRIIVHKNVDILK--TKID--PAILPKEYGGTVPIAD 279

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG30339 (gene:FBgn0050339 transcript:FBtr0088534)

HSP 1 Score: 90.1225 bits (222), Expect = 4.607e-20
Identity = 83/311 (26.69%), Postives = 144/311 (46.30%), Query Frame = 1

Query:  169 KQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYF--QFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQL-QNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFD 1092
            +++A TELNE  ++V A +++ R W+   PHL    D +FL+ FLR  KF   K + +LD+F T+++     PE F  +  D  + +  +   T   +P     DG  L       ++PKE  +  L +   M  E  + ++ +  I G    +DM     SF+ A  D  ++K M    +   P R KG  +   P       N+ +  +  K ++R F + +++++  E IP     LPEEYGG   ++ +   +  K++  + +  +  +   VDE  RP + +      AD      G +G+F K D
Sbjct:   12 RRIAETELNEVEERVPADLKALRDWLAKQPHLRARQDDQFLVGFLRGCKFSLEKTKSKLDHFYTIKTLM---PELFGKRLVDERNLILCR-SGTYVRLPKPWGTDGPRLQLTNYEKFDPKEFKLLDLFRYQTMITEQSIREDDHSNISGYVEIVDMAKMSLSFL-AQLDFTLIKRMGIFAEKAQPTRLKGVHLINCPKEGVALLNLAKSLMPSKLQQR-FHVYKNLEQLNEVIP--REYLPEEYGGNNGRIADIQAEAEKKLLSYESYFAEDSQYGVDEQLRPGKRVN-----ADSI---FGAEGSFRKLD 306

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Match: ttpal (tocopherol (alpha) transfer protein-like [Source:ZFIN;Acc:ZDB-GENE-030131-296])

HSP 1 Score: 95.1301 bits (235), Expect = 1.925e-21
Identity = 72/258 (27.91%), Postives = 121/258 (46.90%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            A  EL E P+     +++ R  + K  P+L    D  FLL FLR  KFD+ +A + L N+    +S R  PE FQ  D+  +  +       +  L R    G  +       W P + P    ++ ++++LE  +Q +  Q+ G+   +D  G G S   +   P + K +  + QD +PIR K   I  EP  +   + I++ FL EK  +R      D+      IP  +++LP+EYGG   ++D  +  W++ +
Sbjct:   42 AREELQEKPEWRLRDVQALRDMILKDHPNLRTRLDDAFLLRFLRARKFDYDRALQLLLNY---HASRRAWPEVFQ--DLKPSTVKHVLDLGFLTVLPRPDPQGRYILCLRPGKWKPNDYPFVDNIRAIYLTLEKLIQPEETQVNGVVILVDYAGVGLS-QASNPGPLLAKKVVGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLASLHRVIP--QSVLPQEYGGVSGRLD--MSAWSRTL 289

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Match: ttpal (tocopherol (alpha) transfer protein-like [Source:ZFIN;Acc:ZDB-GENE-030131-296])

HSP 1 Score: 91.2781 bits (225), Expect = 1.553e-20
Identity = 66/235 (28.09%), Postives = 111/235 (47.23%), Query Frame = 1

Query:  244 VKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            +K  P+L    D  FLL FLR  KFD+ +A + L N+    +S R  PE FQ  D+  +  +       +  L R    G  +       W P + P    ++ ++++LE  +Q +  Q+ G+   +D  G G S   +   P + K +  + QD +PIR K   I  EP  +   + I++ FL EK  +R      D+      IP  +++LP+EYGG   ++D  +  W++ +
Sbjct:    3 LKDHPNLRTRLDDAFLLRFLRARKFDYDRALQLLLNY---HASRRAWPEVFQ--DLKPSTVKHVLDLGFLTVLPRPDPQGRYILCLRPGKWKPNDYPFVDNIRAIYLTLEKLIQPEETQVNGVVILVDYAGVGLS-QASNPGPLLAKKVVGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLASLHRVIP--QSVLPQEYGGVSGRLD--MSAWSRTL 227

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Match: clvs2 (clavesin 2 [Source:NCBI gene;Acc:566769])

HSP 1 Score: 82.0333 bits (201), Expect = 4.795e-17
Identity = 71/287 (24.74%), Postives = 125/287 (43.55%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKA-----------QKRLDNFCTVRSSARGHPEYFQ--FPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRD 951
            T+   GL+    + A  EL E+P  ++  I+  R  + + P +    TD  F+L FLR  KF+H +A           Q+ LD F  ++++  G  +  +  FP +             +   GR +    L    +N W+        +++ + +SLE  +++  LQ+ G    +D      +F +A    P +++      QD +P RF G     +P +    Y ++  FL +K RKR+F    ++    + I  L  +LP E GG  P  D  +  WA+ + D
Sbjct:    2 THLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQALKDGFPGV----------LSNLDRYGRKI----LVLFAAN-WDQSRYTFVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNF--TFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLI--LPEILPSELGGMLPPYD--MGTWARTLLD 267

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Match: rlbp1a (retinaldehyde binding protein 1a [Source:ZFIN;Acc:ZDB-GENE-040426-1662])

HSP 1 Score: 80.8777 bits (198), Expect = 1.240e-16
Identity = 76/278 (27.34%), Postives = 122/278 (43.88%), Query Frame = 1

Query:  154 LTDRDKQVALTELNEDPKQVNAHIESFRRWVKS------------MPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQ------FPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGM------KAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMD 915
            L D  KQ A  ELNE  ++  + I+  R  +K                 +   DS  LL F+R  KFD A+A + +  +   R   R +PE F+           +A + +   T+     GR V    L F + N W+ +E+   + ++   + LE  L+N+  QI G       K F   H  G    E       +K M  + QD +P RFK   +  +P +++  YN+++ F+  K  +RVF +  D   G+ +  G E +LP ++ G GP  D
Sbjct:   39 LPDHTKQKAKDELNETDEKRASAIKELRAMIKDKAGQGDEVAKTVQDKFSKEPDS-LLLRFIRARKFDVARAHELMKGYVRFR---RDYPELFENLTPEAVRSTIEAGYPRILSTRDKN--GRVV----LLFNIDN-WDLEEVTFDETLRAYCVILEKLLENEETQINGFVLIENFKGFTMQHASGIKHTE-------LKKMVDMLQDSFPARFKAVHVIHQPWYFTTTYNVVKPFMKSKLLERVF-VHGDELDGYLRDFGAE-ILPPDFDGTGPACD 296

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Query:  154 LTDRDKQVALTELNEDPKQVNAHIESFRRWVKS------------MPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQ------FPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGM------KAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMD 915
            L D  KQ A  ELNE  ++  + I+  R  +K                 +   DS  LL F+R  KFD A+A + +  +   R   R +PE F+           +A + +   T+     GR V    L F + N W+ +E+   + ++   + LE  L+N+  QI G       K F   H  G    E       +K M  + QD +P RFK   +  +P +++  YN+++ F+  K  +RVF +  D   G+ +  G E +LP ++ G GP  D
Sbjct:   39 LPDHTKQKAKDELNETDEKRASAIKELRAMIKDKAGQGDEVAKTVQDKFSKEPDS-LLLRFIRARKFDVARAHELMKGYVRFR---RDYPELFENLTPEAVRSTIEAGYPRILSTRDKN--GRVV----LLFNIDN-WDLEEVTFDETLRAYCVILEKLLENEETQINGFVLIENFKGFTMQHASGIKHTE-------LKKMVDMLQDSFPARFKAVHVIHQPWYFTTTYNVVKPFMKSKLLERVF-VHGDELDGYLRDFGAE-ILPPDFDGTGPACD 296

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: ttpal (tocopherol (alpha) transfer protein-like [Source:NCBI gene;Acc:548930])

HSP 1 Score: 108.612 bits (270), Expect = 3.590e-26
Identity = 76/260 (29.23%), Postives = 126/260 (48.46%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRD 951
            A  EL E P+     +++ R  V K  PHL    D  FLL FLR  KFD+ +A + L N+ + R   +  PE F   D+  +  +    +  +  L  T  +G  +       W P++ PI + ++ +++SLE  ++++  Q+ G+    D +G G +       P + K +  + QD +PIR K   +  EP  +   + I++ FL EK  KR F    D+      IP  +++LPEEYGG   K+D     W++ + D
Sbjct:   40 AREELQEKPEWRLRDVQALRDMVWKDYPHLKTRVDDSFLLRFLRARKFDYDRALQLLVNYYSCR---KAWPEVFT--DLRPSAVKPVLDSGFLTVLPHTDTEGRRIVCIRPGCWIPRDYPITENIRAIYLSLEKLVESEETQVNGIVILADYNGVGLTHASHFG-PFIAKKVIGILQDGFPIRIKAVNVINEPRIFKGIFAILKPFLKEKIVKRFFLHGSDLNSLHANIP--KSILPEEYGGTAGKLDTT--AWSQILLD 289

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: thg1l (tRNA-histidine guanylyltransferase 1-like [Source:Xenbase;Acc:XB-GENE-966760])

HSP 1 Score: 87.8113 bits (216), Expect = 7.885e-19
Identity = 79/289 (27.34%), Postives = 128/289 (44.29%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGV-SNL--------------WNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRD 951
            T+   GL+    + A  ELNE+P  ++  I+  R  V + P +    TD  F+L FLR  KF+H +A + L              +YF++   N  +F+ F  T   I  G   DG   F GV SNL              W+     +  +++ + +SLE  +++  LQ+ G    +D      +F +A    P +++      QD +P RF G     +P +    Y ++  FL EK RKR+F    ++    + I     +LP E+GG  P  D  +  WA+ + D
Sbjct:    2 THLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLL-------------AQYFEYRQQNLDMFKNFKATDPGIKQGLK-DG---FPGVLSNLDHFGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNF--TFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIH--PEILPSEFGGMLPPYD--MGTWARTLLD 267

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: clvs1 (clavesin 1 [Source:NCBI gene;Acc:100037913])

HSP 1 Score: 87.0409 bits (214), Expect = 1.461e-18
Identity = 73/293 (24.91%), Postives = 127/293 (43.34%), Query Frame = 1

Query:  106 QTFKQSKMADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKA-----------QKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            Q+ +   +  T+ + GL+    + +  ELNE+P  ++  I+  R  + + P +    TD  F+L FLR  KF+  +A           Q  LD F  +++           P I  A+ + F    +     R   G  +    +  W+        +++ + +SLEV +++Q LQI G    +D      SF +A    P +++      QD +P RF G     +P +    Y I++ FL +K RKR+F    ++    + I      LP E+GG  P  D  +  WA+ +
Sbjct:   11 QSIRVEDLKMTHLHAGLSPETIEKSRLELNENPDTLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFNQMEAFRLLAQYFQYRQLNLDMFKNLKADD---------PGIKRALMDGFPGVLE----NRDHYGRKILLLFAANWDQSRNSFVDILRAILLSLEVLIEDQELQINGFILIIDWSNF--SFKQASKLTPSILRLAIEGLQDSFPARFGGVHFVNQPWYIHALYTIIKPFLKDKTRKRIFLHGNNLNSLHQLIH--PDCLPSEFGGTLPPYD--MGTWARTL 284

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: clvs1 (clavesin 1 [Source:NCBI gene;Acc:100037913])

HSP 1 Score: 85.5001 bits (210), Expect = 4.884e-18
Identity = 72/283 (25.44%), Postives = 123/283 (43.46%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKA-----------QKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            T+ + GL+    + +  ELNE+P  ++  I+  R  + + P +    TD  F+L FLR  KF+  +A           Q  LD F  +++           P I  A+ + F    +     R   G  +    +  W+        +++ + +SLEV +++Q LQI G    +D      SF +A    P +++      QD +P RF G     +P +    Y I++ FL +K RKR+F    ++    + I      LP E+GG  P  D  +  WA+ +
Sbjct:    2 THLHAGLSPETIEKSRLELNENPDTLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFNQMEAFRLLAQYFQYRQLNLDMFKNLKADD---------PGIKRALMDGFPGVLE----NRDHYGRKILLLFAANWDQSRNSFVDILRAILLSLEVLIEDQELQINGFILIIDWSNF--SFKQASKLTPSILRLAIEGLQDSFPARFGGVHFVNQPWYIHALYTIIKPFLKDKTRKRIFLHGNNLNSLHQLIH--PDCLPSEFGGTLPPYD--MGTWARTL 265

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: rlbp1 (retinaldehyde binding protein 1 [Source:NCBI gene;Acc:448050])

HSP 1 Score: 82.8037 bits (203), Expect = 3.553e-17
Identity = 76/316 (24.05%), Postives = 136/316 (43.04%), Query Frame = 1

Query:   13 STFSWQLINQTENQLIGVNHRFCRINLKDFLQTFKQSKMADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN---CPT--------DSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDIN-DAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAI 924
            +T +++++++ E  L     +  R+  KD    F +      YT         Q A  ELNE  ++  + ++  R  V+   +     C             F L F+R  KFD ++A + L  +   R     +PE F+  D+  +AV          I   R  +G  +       W+ +EI   ++++   + LE  L+N+  QI G     +  G        +  P  +K M  + QD +P RFK      +P +++  YN+++ FL  K  +RVF   +D++  +++I     +LP ++GG  PK D  I
Sbjct:   10 ATGTYRIVSEEEQSL---RAKLERLTTKDHGSVFGKCGKLPEYTI--------QKAKDELNETEEKRESAVKELRALVQEKANAGDELCKAVADKVKDKGDDFFLRFIRARKFDVSRAYELLKGYVNFRQQ---YPELFE--DLTPEAVRSTIEAGYPGILTSRDKNGRVILLFNIESWDYEEITFDEILRAYCIILESLLENEETQINGFCIIENFKGFTMQQASGIK-PSELKKMVDMLQDSFPARFKAVHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLEGFYKEIDA--DILPADFGGNLPKYDGKI 306

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Match: Ttpal (tocopherol (alpha) transfer protein-like [Source:MGI Symbol;Acc:MGI:1923330])

HSP 1 Score: 92.4337 bits (228), Expect = 1.719e-20
Identity = 73/259 (28.19%), Postives = 118/259 (45.56%), Query Frame = 1

Query:  151 GLTDRDKQVALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEA 921
             LT+     A  EL E P+     +++ R  V K  P+L+   D  FLL FLR  KFD+ +A + L N+   R   R  PE F   ++  +  +    +  +  L  T   G  +     + W P   PI + ++ ++++LE  +Q++  Q+ G+    D  G   S       P + K +  + QD +PIR K   I  EP  +   + I++ FL EK   R F    D+      +P    +LP+EYGG   ++D A
Sbjct:   35 SLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCR---RSWPEVFS--NLRPSALKDVLNSGFLTVLPHTDPRGCHVLCIRPDRWIPSNYPITENIRAVYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RNILPKEYGGTAGELDTA 285

[Close]

Query:  151 GLTDRDKQVALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEA 921
             LT+     A  EL E P+     +++ R  V K  P+L+   D  FLL FLR  KFD+ +A + L N+   R   R  PE F   ++  +  +    +  +  L  T   G  +     + W P   PI + ++ ++++LE  +Q++  Q+ G+    D  G   S       P + K +  + QD +PIR K   I  EP  +   + I++ FL EK   R F    D+      +P    +LP+EYGG   ++D A
Sbjct:   35 SLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCR---RSWPEVFS--NLRPSALKDVLNSGFLTVLPHTDPRGCHVLCIRPDRWIPSNYPITENIRAVYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RNILPKEYGGTAGELDTA 285

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Match: Clvs2 (clavesin 2 [Source:MGI Symbol;Acc:MGI:2443223])

HSP 1 Score: 86.2705 bits (212), Expect = 2.251e-18
Identity = 80/307 (26.06%), Postives = 135/307 (43.97%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQT----KQMIPLG-----RTVD--GETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDF-YTKGSPWANISVDESKRPVE 1014
            T+   GL+    + A  ELNE+P  ++  I+  R  V + P +    TD  F+L FLR  KF H +A + L              +YF++   N  +F+ F  T    KQ +  G       +D  G  +    +  W+     +  +++ + +SLE  +++  LQ+ G    +D      +F +A    P +++      QD +P RF G     +P +    Y ++  FL EK RKR+F    ++    + I     +LP E+GG  P  D  +  WA+ + D  Y   S +   +VD    PV+
Sbjct:    2 THLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLL-------------AQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNF--TFKQASKLTPNMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIH--PEILPSEFGGMLPPYD--MGTWARTLLDHEYDDDSEY---NVDSYNMPVK 286

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Match: Clvs1 (clavesin 1 [Source:MGI Symbol;Acc:MGI:1921688])

HSP 1 Score: 85.1149 bits (209), Expect = 6.270e-18
Identity = 77/296 (26.01%), Postives = 127/296 (42.91%), Query Frame = 1

Query:  103 LQTFKQSKMADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDG-------------ETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            L T++      T+   GL+    + A  ELNE+P  ++  I+  R  + + P +    TD  F+L FLR  KF  A A + L              +YFQ+  +N  +F+ F      I     +DG             + L    +N W+        +++ + +SLEV +++  LQI G    +D      SF +A    P ++K      QD +P RF G     +P +    Y +++ FL +K RKR+F    ++    + I      LP E+GG  P  D  +  WA+ +
Sbjct:   13 LSTWEGDLAKMTHLQAGLSPDTIEKARLELNENPDILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLL-------------AQYFQYRQLNLDMFKNFKADDPGIKRA-LIDGFPGVLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNF--SFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIH--PEFLPSEFGGTLPPYD--MGTWARTL 287

[Close]

Query:  103 LQTFKQSKMADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDG-------------ETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            L T++      T+   GL+    + A  ELNE+P  ++  I+  R  + + P +    TD  F+L FLR  KF  A A + L              +YFQ+  +N  +F+ F      I     +DG             + L    +N W+        +++ + +SLEV +++  LQI G    +D      SF +A    P ++K      QD +P RF G     +P +    Y +++ FL +K RKR+F    ++    + I      LP E+GG  P  D  +  WA+ +
Sbjct:   13 LSTWEGDLAKMTHLQAGLSPDTIEKARLELNENPDILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLL-------------AQYFQYRQLNLDMFKNFKADDPGIKRA-LIDGFPGVLENRDHYGRKILLLFAAN-WDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNF--SFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIH--PEFLPSEFGGTLPPYD--MGTWARTL 287

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9BTX7|TTPAL_HUMAN (Alpha-tocopherol transfer protein-like OS=Homo sapiens OX=9606 GN=TTPAL PE=1 SV=2)

HSP 1 Score: 93.5893 bits (231), Expect = 4.916e-20
Identity = 70/250 (28.00%), Postives = 117/250 (46.80%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEA 921
            A  EL E P+     +++ R  V K  P+L+   D  FLL FLR  KFD+ +A + L N+ + R   R  PE F   ++  +  +    +  +  L  T   G  +     + W P   PI + ++ ++++LE  +Q++  Q+ G+    D  G   S       P + K +  + QD +PIR K   +  EP  +   + I++ FL EK   R F    D+      +P   ++LP+EYGG   ++D A
Sbjct:   43 AREELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCR---RSWPEVFN--NLKPSALKDVLASGFLTVLPHTDPRGCHVVCIRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RSILPKEYGGTAGELDTA 284

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5RFR0|TTPAL_PONAB (Alpha-tocopherol transfer protein-like OS=Pongo abelii OX=9601 GN=TTPAL PE=2 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 5.417e-20
Identity = 70/250 (28.00%), Postives = 117/250 (46.80%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEA 921
            A  EL E P+     +++ R  V K  P+L+   D  FLL FLR  KFD+ +A + L N+ + R   R  PE F   ++  +  +    +  +  L  T   G  +     + W P   PI + ++ ++++LE  +Q++  Q+ G+    D  G   S       P + K +  + QD +PIR K   +  EP  +   + I++ FL EK   R F    D+      +P   ++LP+EYGG   ++D A
Sbjct:   43 AREELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCR---RSWPEVFN--NLKPSALKDVLASGFLTVLPHTDPRGCHVVCIRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RSILPKEYGGTAGELDTA 284

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9D3D0|TTPAL_MOUSE (Alpha-tocopherol transfer protein-like OS=Mus musculus OX=10090 GN=Ttpal PE=1 SV=3)

HSP 1 Score: 92.4337 bits (228), Expect = 1.202e-19
Identity = 73/259 (28.19%), Postives = 118/259 (45.56%), Query Frame = 1

Query:  151 GLTDRDKQVALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEA 921
             LT+     A  EL E P+     +++ R  V K  P+L+   D  FLL FLR  KFD+ +A + L N+   R   R  PE F   ++  +  +    +  +  L  T   G  +     + W P   PI + ++ ++++LE  +Q++  Q+ G+    D  G   S       P + K +  + QD +PIR K   I  EP  +   + I++ FL EK   R F    D+      +P    +LP+EYGG   ++D A
Sbjct:   35 SLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCR---RSWPEVFS--NLRPSALKDVLNSGFLTVLPHTDPRGCHVLCIRPDRWIPSNYPITENIRAVYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RNILPKEYGGTAGELDTA 285

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|Q95KF7|CLVS2_MACFA (Clavesin-2 OS=Macaca fascicularis OX=9541 GN=CLVS2 PE=2 SV=2)

HSP 1 Score: 86.2705 bits (212), Expect = 1.417e-17
Identity = 80/310 (25.81%), Postives = 137/310 (44.19%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQT----KQMIPLG-----RTVD--GETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDF-YTKGSPWANISVDESKRPVETLK 1023
            T+   GL+    + A  ELNE+P  ++  I+  R  V + P +    TD  F+L FLR  KF H +A + L              +YF++   N  +F+ F  T    KQ +  G       +D  G  +    +  W+     +  +++ + +SLE  +++  LQ+ G    +D      +F +A    P +++      QD +P RF G     +P +    Y ++  FL EK RKR+F    ++    + I     +LP E+GG  P  D  +  WA+ + D  Y   S +   +VD    PV+ ++
Sbjct:    2 THLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLL-------------AQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNF--TFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIH--PEILPSEFGGMLPPYD--MGTWARTLLDHEYDDDSEY---NVDSYSMPVKEVE 289

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5SYC1|CLVS2_HUMAN (Clavesin-2 OS=Homo sapiens OX=9606 GN=CLVS2 PE=1 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 1.417e-17
Identity = 80/310 (25.81%), Postives = 137/310 (44.19%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQT----KQMIPLG-----RTVD--GETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDF-YTKGSPWANISVDESKRPVETLK 1023
            T+   GL+    + A  ELNE+P  ++  I+  R  V + P +    TD  F+L FLR  KF H +A + L              +YF++   N  +F+ F  T    KQ +  G       +D  G  +    +  W+     +  +++ + +SLE  +++  LQ+ G    +D      +F +A    P +++      QD +P RF G     +P +    Y ++  FL EK RKR+F    ++    + I     +LP E+GG  P  D  +  WA+ + D  Y   S +   +VD    PV+ ++
Sbjct:    2 THLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLL-------------AQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNF--TFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIH--PEILPSEFGGMLPPYD--MGTWARTLLDHEYDDDSEY---NVDSYSMPVKEVE 289

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A4E0RHZ7 (Alpha-tocopherol transfer protein OS=Fasciola hepatica OX=6192 GN=D915_000833 PE=4 SV=1)

HSP 1 Score: 248.44 bits (633), Expect = 2.466e-76
Identity = 122/316 (38.61%), Postives = 183/316 (57.91%), Query Frame = 1

Query:  148 DGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSS-ARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFD 1092
            D L    +Q A  EL+ED + + AHIESF+RWV S+PH+  P D + LL FLR AK+ H KAQ RLDNFCT+R+S   G P +F FP +ND +   + +   ++ LGRT D   +       W+P  +P+  +  + +M+LE  + +   QI G   F DM G     +    D   +K   +V+Q+  P+R K  + Y EP    V + +M+ ++++K R+R+ R+K +I K ++K+PGL+ L+P EYGGK  K+ + I+  A+  R+FY+K  PW  + VDESKRP     Y  +Y D   +  GTKGT+   D
Sbjct:    7 DTLPQNLRQKARKELHEDERHLKAHIESFQRWVDSLPHITYPKDPKLLLPFLRHAKYRHDKAQARLDNFCTLRASDLNGVPHWFHFPPVNDPIVNTYLKAGLVVELGRTKDDVLILLIRIGSWDPDILPMNLIRPLGYMNLERYVLDPVTQIAGYGLFFDMTGLSSRQLMHRKDKSEIKLEMKVFQEGLPLRVKHLIYYNEPAIVDVMFKLMDTWISDKIRQRMLRVKTNIDKAYDKVPGLKDLMPAEYGGKNGKLSDLIENHARRFREFYSKPPPWIGVRVDESKRPDSAKNYMREYKDVNIDIFGTKGTYISLD 322

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A504YET3 (CRAL-TRIO domain-containing protein OS=Fasciola gigantica OX=46835 GN=FGIG_03808 PE=4 SV=1)

HSP 1 Score: 244.588 bits (623), Expect = 1.270e-74
Identity = 124/327 (37.92%), Postives = 185/327 (56.57%), Query Frame = 1

Query:  148 DGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSS-ARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFG-----------VSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFD 1092
            D L    +Q A  EL+ED + + AHIESF+RWV S+PH+  P D + LL FLR AK+ H KAQ RLDNFCT+R+S   G P++F FP +ND +   + +   M+ LGRT D   +              +   W P  +P+  +  + +M+LE  L +   QI G   F+DM G     +    D   +K   +V+Q+  P+R K  + Y EP    V + +M+ ++++K R+R+ R+K +I K ++K+PGL+ L+P EYGGK  K+ + I+  A+  R+FY+K  PW  + VDESKRP     Y  +Y D   +  GTKGT+   D
Sbjct:    7 DTLPQNLRQKARKELHEDERHLRAHIESFQRWVNSLPHITYPKDPKLLLPFLRHAKYRHDKAQARLDNFCTLRASDLNGAPQWFHFPPVNDPIVNTYLKAGLMVELGRTKDDVLILLLRIAILFIRDKKLVGSWEPDILPMNLMRPLNYMNLERYLLDPVTQIAGYGLFLDMTGLNSRQLMHRKDKSEIKLEMKVFQEGLPLRVKHLIYYNEPAIVDVMFKLMDTWISDKIRQRMLRVKTNIDKAYDKVPGLKDLMPVEYGGKNGKLSDLIENHARRFREFYSKPPPWIGVRVDESKRPDSAKNYMREYKDVNVDIFGTKGTYISLD 333

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A267DVC9 (CRAL-TRIO domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023111g2 PE=4 SV=1)

HSP 1 Score: 237.654 bits (605), Expect = 4.436e-72
Identity = 126/323 (39.01%), Postives = 183/323 (56.66%), Query Frame = 1

Query:  133 DTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKI-PGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKG--SPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFD 1092
            + Y Y+G+  +DK+ A  EL+E+P QV AHI S RRWV S PHL CPTD  FLL FLR AKFD ++AQ+ +DNFCTVR S RG PE+F+   ++  + E+  +    I LG   DGE + +   + ++P  I    L +  +M+ +  ++ + +QI G +  M++    K   +A  +P+    M R WQD +PIR K  V + EP ++ + + I+  F+ EK RKR+ R   D  K  + I PG E LLP E GG+   M+E + +  K  +    +   +  A I+VDESKR   T  Y + Y D    S+G  GTFTK D
Sbjct:    8 NVYNYEGVDPKDKKKAQKELHENPDQVRAHIASLRRWVTSAPHLTCPTDDAFLLRFLRTAKFDQSRAQQLVDNFCTVRKSPRGSPEWFEPLPLDSPIIEEALKLPMNIFLGYNDDGEGIIYSSMDNYDPDRINFNDLARFAYMNADTMMKPEKIQINGCRFIMNLKNANKKQTQAWENPRTAFKMMRNWQDAFPIRTKALVYWHEPAFFELMFRIIMPFMKEKLRKRLHRCGTDFSKLKKAIGPGAERLLPPEMGGQNRPMEELLAERYKMFKSAEAQAERAKLATITVDESKRLPTTKDYLKTYDDSADPSMGIAGTFTKLD 330

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A267GCN2 (CRAL-TRIO domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023111g3 PE=4 SV=1)

HSP 1 Score: 237.654 bits (605), Expect = 4.784e-72
Identity = 126/323 (39.01%), Postives = 183/323 (56.66%), Query Frame = 1

Query:  133 DTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKI-PGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKG--SPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFD 1092
            + Y Y+G+  +DK+ A  EL+E+P QV AHI S RRWV S PHL CPTD  FLL FLR AKFD ++AQ+ +DNFCTVR S RG PE+F+   ++  + E+  +    I LG   DGE + +   + ++P  I    L +  +M+ +  ++ + +QI G +  M++    K   +A  +P+    M R WQD +PIR K  V + EP ++ + + I+  F+ EK RKR+ R   D  K  + I PG E LLP E GG+   M+E + +  K  +    +   +  A I+VDESKR   T  Y + Y D    S+G  GTFTK D
Sbjct:    8 NVYNYEGVDPKDKKKAQKELHENPDQVRAHIASLRRWVTSAPHLTCPTDDAFLLRFLRTAKFDQSRAQQLVDNFCTVRKSPRGSPEWFEPLPLDSPIIEETLKLPMNIFLGYNDDGEGIIYSSMDNYDPDRINFNDLARFAYMNADTMMKPEKIQINGCRFIMNLKNANKKQTQAWENPRTAFKMMRNWQDAFPIRTKALVYWHEPAFFELMFRIIMPFMKEKLRKRLHRCGTDFSKLKKAIGPGAERLLPPEMGGQNRPMEELLAERYKMFKSAEAQAERAKLATITVDESKRLPTTKDYLKTYDDSADPSMGIAGTFTKLD 330

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A1I8IZU0 (CRAL-TRIO domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 237.654 bits (605), Expect = 1.301e-71
Identity = 126/323 (39.01%), Postives = 183/323 (56.66%), Query Frame = 1

Query:  133 DTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKI-PGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKG--SPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFD 1092
            + Y Y+G+  +DK+ A  EL+E+P QV AHI S RRWV S PHL CPTD  FLL FLR AKFD ++AQ+ +DNFCTVR S RG PE+F+   ++  + E+  +    I LG   DGE + +   + ++P  I    L +  +M+ +  ++ + +QI G +  M++    K   +A  +P+    M R WQD +PIR K  V + EP ++ + + I+  F+ EK RKR+ R   D  K  + I PG E LLP E GG+   M+E + +  K  +    +   +  A I+VDESKR   T  Y + Y D    S+G  GTFTK D
Sbjct:    8 NVYNYEGVDPKDKKKAQKELHENPDQVRAHIASLRRWVTSAPHLTCPTDDAFLLRFLRTAKFDQSRAQQLVDNFCTVRKSPRGSPEWFEPLPLDSPIIEEALKLPMNIFLGYNDDGEGIIYSSMDNYDPDRINFNDLARFAYMNADTMMKPEKIQINGCRFIMNLKNANKKQTQAWENPRTAFKMMRNWQDAFPIRTKALVYWHEPAFFELMFRIIMPFMKEKLRKRLHRCGTDFSKLKKAIGPGAERLLPPEMGGQNRPMEELLAERYKMFKSAEAQAERAKLATITVDESKRLPTTKDYLKTYDDSADPSMGIAGTFTKLD 330

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: ttpal (alpha tocopherol transfer protein like [Source:NCBI gene;Acc:103043466])

HSP 1 Score: 94.3597 bits (233), Expect = 2.779e-21
Identity = 73/258 (28.29%), Postives = 118/258 (45.74%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            A  EL E P+     +++ R  + K  P+L    D  FLL FLR  KFD+ +A + L N+     S R  PE FQ  D+  +  +       +  L R    G  +       W P +      ++ ++++LE  +Q +  Q+ G+   +D  G G S   +   P + K +  + QD +PIR K   I  EP  +   + I++ FL EK  +R      D+      IP   ++LPEEYGG   ++D  +  WA+ +
Sbjct:   45 AREELQEKPEWRLRDVQALRDMILKEQPNLRTRLDDAFLLRFLRARKFDYDRAMQLLLNY---HGSRRAWPEVFQ--DLKPSTVKHVLDLGFLTVLPRPDPQGRYILCLRPGKWKPNDYHFVDNIRAIYLTLEKLIQPEETQVNGIVILVDYTGVGLS-QASNPGPLLAKKVVSILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLSSLHRVIP--RSVLPEEYGGVAGRLD--MSAWARTL 292

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: ttpal (alpha tocopherol transfer protein like [Source:NCBI gene;Acc:103043466])

HSP 1 Score: 94.3597 bits (233), Expect = 2.787e-21
Identity = 73/258 (28.29%), Postives = 118/258 (45.74%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
            A  EL E P+     +++ R  + K  P+L    D  FLL FLR  KFD+ +A + L N+     S R  PE FQ  D+  +  +       +  L R    G  +       W P +      ++ ++++LE  +Q +  Q+ G+   +D  G G S   +   P + K +  + QD +PIR K   I  EP  +   + I++ FL EK  +R      D+      IP   ++LPEEYGG   ++D  +  WA+ +
Sbjct:   46 AREELQEKPEWRLRDVQALRDMILKEQPNLRTRLDDAFLLRFLRARKFDYDRAMQLLLNY---HGSRRAWPEVFQ--DLKPSTVKHVLDLGFLTVLPRPDPQGRYILCLRPGKWKPNDYHFVDNIRAIYLTLEKLIQPEETQVNGIVILVDYTGVGLS-QASNPGPLLAKKVVSILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLSSLHRVIP--RSVLPEEYGGVAGRLD--MSAWARTL 293

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: clvs2 (clavesin 2 [Source:NCBI gene;Acc:103047212])

HSP 1 Score: 81.6481 bits (200), Expect = 6.360e-17
Identity = 73/293 (24.91%), Postives = 128/293 (43.69%), Query Frame = 1

Query:  118 QSKMADTYTY--DGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKA-----------QKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRD 951
            Q +  DT T+   GL+    + A  EL E+P  ++  I+  R  + + P +    TD  F+L FLR  KF+H +A           Q+ LD F  ++++          P I  A+ + F     +  L R   G  +    +  W+        +++ + +SLE  +++  LQ+ G    +D      +F +A    P +++      QD +P RF G     +P +    Y ++  FL +K RKR+F    ++    + I  +  +LP E GG  P  D  +  WA+ + D
Sbjct:   11 QGEKEDTMTHLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATD---------PGIKQALKDGF--PGVLSNLDR--HGRKILVLFAANWDQSRYTFVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNF--TFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLI--VPEILPSELGGMLPPYD--MGTWARTLLD 284

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: clvs2 (clavesin 2 [Source:NCBI gene;Acc:103047212])

HSP 1 Score: 80.8777 bits (198), Expect = 1.222e-16
Identity = 70/285 (24.56%), Postives = 124/285 (43.51%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKA-----------QKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRD 951
            T+   GL+    + A  EL E+P  ++  I+  R  + + P +    TD  F+L FLR  KF+H +A           Q+ LD F  ++++          P I  A+ + F     +  L R   G  +    +  W+        +++ + +SLE  +++  LQ+ G    +D      +F +A    P +++      QD +P RF G     +P +    Y ++  FL +K RKR+F    ++    + I  +  +LP E GG  P  D  +  WA+ + D
Sbjct:    2 THLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATD---------PGIKQALKDGF--PGVLSNLDR--HGRKILVLFAANWDQSRYTFVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNF--TFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLI--VPEILPSELGGMLPPYD--MGTWARTLLD 267

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: ttpa (tocopherol (alpha) transfer protein [Source:ZFIN;Acc:ZDB-GENE-030131-4631])

HSP 1 Score: 77.0258 bits (188), Expect = 4.127e-15
Identity = 70/253 (27.67%), Postives = 115/253 (45.45%), Query Frame = 1

Query:  286 FLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDIN-----DAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHG-CGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKG-FEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWAN-ISVD--ESKRPV 1011
            FLL FLR   FD   A K L N+   R          + P+I+      +V          +   R   G  +     + WNPKE    ++ +V  ++ E+ +Q +  QI G+KA  D+ G C   F  A   +P + K ++ V  D +P++ +G  +  EP ++   + ++  FL +K ++RV           +E  P  +A+ P EYGG GP + EA ++W     DF  +   +   +SVD  E+K P 
Sbjct:   48 FLLKFLRARDFDLDLALKLLINYHKWRQ---------ECPEISANLQPSSVIGLLKNNYHGVLKSRDDAGSRILIYRISQWNPKEFSAYEVFRVSLITSELIVQERDTQINGLKAIFDLQGWC---FAHAFQINPFLAKKISSVLTDSFPLKVRGIHLINEPIFFRPVFKMIRPFLPDKIKQRVHIHGSSYTASLYEHFP--KAIFPPEYGGTGPGLAEACEEWT----DFIMQSEDYLQRLSVDLGETKVPA 282

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
Match: ttpal (tocopherol (alpha) transfer protein-like [Source:ZFIN;Acc:ZDB-GENE-030131-296])

HSP 1 Score: 101.679 bits (252), Expect = 2.909e-25
Identity = 65/216 (30.09%), Postives = 104/216 (48.15%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQF--PDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVF 819
            A  EL E+P+     ++  R  +   P +   TD  FLL FLR  KFDH K  K ++++     +    P+ FQ   P    A+    F   +++P  R   G  +       WNP   P+   ++ M+M++E+ +Q++  Q+ G+    D  G   + +   + P +MK +T V QD +PIR KG     EP  +   + +M+ FL EK RKR F
Sbjct:   42 ARVELGENPETRAQEVQKLREALARRPDIPARTDDAFLLRFLRARKFDHEKTFKLVESYYKCHET---WPDIFQNFRPSAVKALLGSGF--IRVLP-ERDSKGRRVIIQSPGKWNPSTTPMMDNIRAMYMTMELLIQSEETQVNGITILADHKGVRLAHVTNFT-PSLMKKITTVMQDAFPIRIKGHNTVNEPSIFKAMFALMKPFLKEKMRKRYF 250

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003570.1 (pep scaffold:Pmarinus_7.0:GL486699:2092:8510:1 gene:ENSPMAG00000003262.1 transcript:ENSPMAT00000003570.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.1814 bits (191), Expect = 7.097e-17
Identity = 56/193 (29.02%), Postives = 88/193 (45.60%), Query Frame = 1

Query:  172 QVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQ--FPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQ--DCYPIRFKGQVI 738
            +VA  EL E P+     I++ R  +K  P +  PTD  FLL FLR  KFD+ KA   +DN+   R   R  P+ F   +P     V E    T    P      G  +      LWNP   P   +++V++M+LE+ ++ +  Q+ G+    D  G G +    +  P  ++ +  V Q     P+   G+V+
Sbjct:   38 EVARQELQEKPEWRLRDIQALRDMLKEHPEIPAPTDDGFLLRFLRARKFDYDKALLLIDNYYKCR---RVWPDVFVNFYPSSVRHVLEAGVVTALPQP---DAQGRRIIVLRPGLWNPAVAPATDMLRVLYMTLEMLVRQEETQVCGLVVLADYAGLGLAHASHLG-PAFVRRVATVLQVGSTPPVSVSGRVV 223

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007468.1 (pep scaffold:Pmarinus_7.0:GL477833:5549:9144:1 gene:ENSPMAG00000006747.1 transcript:ENSPMAT00000007468.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.0182 bits (175), Expect = 1.690e-15
Identity = 36/116 (31.03%), Postives = 59/116 (50.86%), Query Frame = 1

Query:  466 RTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKR 813
            R   G  +       WNP   PI    + M+M+LE+ +Q++  Q+ G+   +D  G G + +   + P +MK +T V QD +PIR KG     EP  +   + +++ F  EK +KR
Sbjct:   34 RDSKGRRVIIQSPGKWNPSTTPIIDNFKAMYMTLELLIQSEETQVNGITILVDHKGMGLAHVTNFT-PSLMKKITTVIQDAFPIRIKGHHTINEPSIFKAMFALIKPFFKEKMQKR 148

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001440.1 (pep scaffold:Pmarinus_7.0:GL476337:1030926:1032713:1 gene:ENSPMAG00000001302.1 transcript:ENSPMAT00000001440.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 43.8986 bits (102), Expect = 6.883e-6
Identity = 22/59 (37.29%), Postives = 30/59 (50.85%), Query Frame = 1

Query:  178 ALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNF 354
            A  EL E+P+     ++  R  +   P +   TD  FLL FLR  KFDH K  K + N+
Sbjct:   13 ARVELGENPETRAQEVQKLREALARRPDIPARTDDAFLLRFLRARKFDHEKTLKLIKNY 71

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Nematostella
Match: EDO33762 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR95])

HSP 1 Score: 54.299 bits (129), Expect = 1.520e-8
Identity = 41/163 (25.15%), Postives = 77/163 (47.24%), Query Frame = 1

Query:  451 MIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAK 939
            M P+G T+    LF G   +W+        L+Q + ++L    ++  +Q  G+   +D      S   A  + K +K +  ++++CYP+ FK   +  +P + S   + +  FL  K + RVF    ++    + IP     LP ++GG   ++D++   WAK
Sbjct:   82 MDPVGSTI--MVLFPG---MWDTDTFSPDTLLQALMLTLMHLSESLTVQSRGVVLLVDFSE-WTSTQAAYLNIKYIKKIVTIFENCYPVVFKSVHLINQPWYISALISFLRPFLTGKVKDRVFLHGNNLTTLHDHIP--PESLPSQFGGDRCEVDQS--YWAK 234

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: ttpal (alpha tocopherol transfer protein like [Source:NCBI gene;Acc:101167039])

HSP 1 Score: 97.8265 bits (242), Expect = 1.830e-22
Identity = 75/268 (27.99%), Postives = 125/268 (46.64%), Query Frame = 1

Query:  154 LTDRDKQVALTELNEDPKQVNAHIESFRRWV-KSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRT-VDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRD 951
            LT   +  A  EL E P+     +++ R  + K  P+L+   D  FLL FLR  KFD+ +A + L N+   R   R  PE FQ  D+  +  +       +  L R    G  +       W P + P    ++ ++++LE  +Q +  Q+ G+   +D  G G S   +   P + K +  + QD +PIR K   I  EP  +   + I++ FL EK  +R      D++     +P   ++LPEEYGG   ++D  +  W++ + D
Sbjct:   36 LTPELEAKAREELQEKPEWRLRDVQALRDMILKEQPNLHTRLDDAFLLRFLRARKFDYDRALQLLLNYHAGR---RAWPEVFQ--DLKPSTVKHVLDLGFLTVLPRPDPSGRYILCLRPGKWKPNDYPFVDNVRAIYLTLEKLIQPEETQVNGIIILVDYTGVGMS-QASNPGPFLAKKVVSILQDGFPIRIKAVNIINEPLIFKGIFAIIKPFLKEKMAERYILHGSDLRSLHRNLPA--SVLPEEYGGTAGRLD--MGAWSRLLLD 293

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: CLVS1 (clavesin-1 [Source:NCBI gene;Acc:101158238])

HSP 1 Score: 87.0409 bits (214), Expect = 8.823e-19
Identity = 75/283 (26.50%), Postives = 124/283 (43.82%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKF----FQTKQMIPLG-----RTVD--GETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEV 945
             + +  L+    + A  ELNE+P  ++  I+  R  + + P +    TD  F+L FLR  KFD  +  + L              +YFQF   N  +F+ F       K+ +  G      + D  G  +    ++ W+        +++ + +SLEV ++N  LQI G    +D      SF +A    P ++K      QD +P RF G     +P +    Y I++ FL +K RKR+F    ++    + I  L   LP E+GG  P  D  +  WA+ +
Sbjct:    2 NHLHSSLSSEMMEKARLELNENPDTLHQDIQQVRDMIVTRPDIGFLRTDDDFILRFLRARKFDQLETFRLL-------------AQYFQFRQQNLDMFQSFKVDDLGIKRALMDGFPGVLESPDQHGRKILILFASNWDQSRNSFIDILRAILLSLEVLIENPELQINGFILIIDWSNF--SFKQASKLTPNILKLAIEGLQDSFPARFGGIHFVNQPWYIHAMYTIIKPFLKDKTRKRIFLHGNNLNSLHQLI--LPECLPSEFGGTLPPYDMGM--WARTL 265

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: clvs2 (clavesin 2 [Source:NCBI gene;Acc:101159632])

HSP 1 Score: 79.7221 bits (195), Expect = 3.341e-16
Identity = 70/287 (24.39%), Postives = 124/287 (43.21%), Query Frame = 1

Query:  136 TYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLN-CPTDSRFLLMFLRVAKFDHAKA-----------QKRLDNFCTVRSSARGHPEYFQ--FPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVS-DPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRD 951
            T+   GL+    + A  EL E+P  ++  I+  R  + + P +    TD  F+L FLR  KF+H +A           Q+ LD F  ++++  G  +  +  FP +             +   GR +    L    +N W+        +++ + +SLE  +++  LQ+ G    +D      +F +A    P +++      QD +P RF G     +P +    Y ++  FL +K RKR+F    ++    + I     +LP E GG  P  D  +  WA+ + D
Sbjct:    2 THLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQALKDGFPGV----------LSNLDKYGRKI----LVLFAAN-WDQSRYTFVDILRAILLSLESMIEDPELQVNGFILIIDWSNF--TFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLIN--PEILPSELGGMMPPYD--MGTWARTLLD 267

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000002803.2 (retinaldehyde-binding protein 1-like [Source:NCBI gene;Acc:101170080])

HSP 1 Score: 72.4034 bits (176), Expect = 7.630e-14
Identity = 59/222 (26.58%), Postives = 103/222 (46.40%), Query Frame = 1

Query:  286 FLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQ--FPDINDAVFEKFFQTKQMIP----LGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGM------KAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMD 915
             LL FLR  KF+  +A + L  +   R   + +PE F+   P+   +  E  +    ++P     GR V    L F + N W+ +EI   ++++   + LE  L+N+  QI G       K F   H  G    E       +K M  + QD +P RFK   +  +P +++  YN+++ F+  K  +RV+   E+++   ++      +LP ++ GK P  D
Sbjct:   86 LLLRFLRARKFNVVRAHELLKGYVRFR---KDYPELFENLTPEAVRSTIEAGYPV--VLPSRDKYGRVV----LLFNIEN-WDLEEITFDEVLRAYCVILEKLLENEETQINGFVLIENFKGFTMQHASGIKTTE-------LKKMVDMLQDSFPARFKAVHVIHQPWYFTTTYNVVKPFMKAKLLERVYVHGEELESYLKEFDA--NILPSDFEGKAPVAD 288

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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: TTPA (alpha tocopherol transfer protein [Source:NCBI gene;Acc:101155881])

HSP 1 Score: 71.633 bits (174), Expect = 1.078e-13
Identity = 64/264 (24.24%), Postives = 109/264 (41.29%), Query Frame = 1

Query:  169 KQVALTELNEDPKQVNAHIESFRRWVKSMPH--LNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDF 954
            K   L+EL ++ +Q+ A +   R+            P    FLL FLR   FD   + K L N+   R   R  PE       +  +         ++P         L + +   WN K+    ++ +V  M+ E+       Q  G+KA  D+ G        + +P + K ++ V  D +P++ +G  +  EP ++   + ++  FL EK ++R+     D             +LP EYGG GP +DEA   W  ++  F
Sbjct:   14 KTPELSELPDESEQLRAFVSRLRQAADEAGGGPAGPPLSDGFLLKFLRARDFDVELSLKLLLNYLRWR---RDSPEISSCLSPSSVLGLLHMSYHAVLPQRDHAGSRVLIYRIGQ-WNTKDWSPYQVFRVSLMTSEIISMETETQRRGLKAIFDLQGWSLGHALQI-NPSLAKKISCVLSDSFPLKVRGIHLVNEPRFFRPVFAMIRPFLPEKIKQRIHMHGADFHSDLRHF-FHPHVLPPEYGGHGPGIDEACQDWTNQLLHF 271

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BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009988.1 (SMESG000009988.1)

HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0
Identity = 324/324 (100.00%), Postives = 324/324 (100.00%), Query Frame = 1

Query:  127 MADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFDAF 1098
            MADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFDAF
Sbjct:    1 MADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFDAF 324

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BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009876.1 (SMESG000009876.1)

HSP 1 Score: 355.91 bits (912), Expect = 5.138e-122
Identity = 154/322 (47.83%), Postives = 225/322 (69.88%), Query Frame = 1

Query:  127 MADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFD 1092
            M + Y Y G++++ KQ A+ ++ E+P QVNAHIESFRRW+KSMPHL CPTD++FL+ FLRV+KFDH +A+KR+DN+CTVR+S RG P +F    IND +   + +T   +PLGRT +GET+F   + +W+P++IP  KL+ +MFM++++   ++  QI+GMK  +D+    +  ME+  DPK MK + RV Q+ YP+R KG + Y EP  + + + ++ FF+NEK + R  RIK DI K  EK PGL+ +LP EYGG+G  + E  +KW    ++FY  G+P +  SVDESKRP E+  Y  +Y DY G++LGT+GT+TKF+
Sbjct:    1 MTERYEYSGISEKTKQFAIDDIGENPSQVNAHIESFRRWLKSMPHLQCPTDAKFLMKFLRVSKFDHKRAEKRIDNYCTVRASPRGSPSFFNTFSINDPIINTYLETGMHLPLGRTENGETIFLVRTKVWDPEQIPFPKLIILMFMAMDIICNDEETQIHGMKMIIDLKDASRKAMESWGDPKYMKQINRVMQESYPLRIKGTIFYNEPVIFDIVFQVLSFFMNEKMKSRTIRIKNDINKAIEKNPGLDKILPMEYGGQGGTITECSEKWKIRFKEFYKNGNPVSGFSVDESKRPQESASYLAEYPDYEGQTLGTQGTYTKFE 322

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BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009878.1 (SMESG000009878.1)

HSP 1 Score: 345.895 bits (886), Expect = 5.079e-118
Identity = 157/321 (48.91%), Postives = 223/321 (69.47%), Query Frame = 1

Query:  127 MADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESL-GTKGTFTK 1086
            MAD Y Y  L+ RD+++   E++E+P QVNAHIESFRRWV SMPHL CPTDSRFLL FLR+AK+DH+KAQKRLDNFCT+R+S +G P YF F  IN  + EK F+  Q +P+G+T   E +    +  W+  E+ ++ L+QV++MS ++ L  +  QI G+ +F D+  C +  +E  SDPK++K +TR+WQD +PIR KG ++Y+EP  + V   I+EFF++EKHRKR F+I ++ +K F  IPGLE ++P EYGGKG  + + ++ W KEV+DF++    W N  VDE KR  +T  + + Y DY GE++ GT G+F K
Sbjct:    1 MADCYDYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQI-DNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIK 320

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BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009877.1 (SMESG000009877.1)

HSP 1 Score: 345.51 bits (885), Expect = 7.120e-118
Identity = 152/323 (47.06%), Postives = 223/323 (69.04%), Query Frame = 1

Query:  127 MADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESL-GTKGTFTKFD 1092
            MAD Y Y+ L+ RD ++   E+ ED  QVNAHIESFRRWV SMPHL CPTDS+FLLMFLR AKFDH+ AQ+RLDNFCT+RSS RG P +F+FP + +++ EK  ++ Q IP+G+   GE +    +  W P+EI ++ ++QV++M+ ++ L  +  QI G+ +  D+ GC +  +EA SDP + K + R+WQD +PIR KG ++Y+ P  + +   IMEFF+ +KH+KR+ +I     K F K+ GL+ ++P EYGG G K+ + ++ W  EV  FY KG PW+ ISVDE+KRP +T+ +   Y +Y GE++ GT G++TK++
Sbjct:    1 MADVYKYETLSVRDSEILKNEIKEDKNQVNAHIESFRRWVVSMPHLKCPTDSKFLLMFLRTAKFDHSVAQRRLDNFCTIRSSPRGSPRFFKFPSLKNSIIEKVLRSHQNIPMGKDSAGEMVLLFKTGDWKPEEISVENILQVVYMTFDLILTRESTQINGIVSIFDLEGCCRKTLEAWSDPHLTKNIMRIWQDAFPIRMKGIILYKPPTLFHIILKIMEFFMIDKHKKRILQIDSQ-DKLFSKVSGLKEIMPTEYGGNGGKLKDKVESWIGEVETFYDKGDPWSFISVDENKRPGDTVSFLRNYEEYKGETIGGTPGSYTKYE 322

[Close]

BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009872.1 (SMESG000009872.1)

HSP 1 Score: 343.969 bits (881), Expect = 2.575e-117
Identity = 152/322 (47.20%), Postives = 223/322 (69.25%), Query Frame = 1

Query:  127 MADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESLGTKGTFTKFD 1092
            M D Y Y G+++  K+ A+  LNE+P+QVNAHIES RRWVKSMPH+NCPTD  FLL FLRVAKFDH KA++RLDNFCT RSS +G  E+F+F  I D V + F  +K  IPLG+   GE +F   SN+W+P++IP+ KL+ ++FM L++ +  +  QI+G++  +D++   +  +E+ ++PK++K   +V Q+ YP+R KGQ+ Y EP  + + Y ++  F+N+K ++R FR+K DI+K  EKIPGLE +LP EY G+G  ++E  +KW  +   +Y  G+P+  ISVDESKRP     Y   ++DY  ++ GT G+FTKF+
Sbjct:    1 MNDRYEYSGVSENSKKAAVEYLNENPEQVNAHIESLRRWVKSMPHINCPTDGNFLLKFLRVAKFDHDKAERRLDNFCTARSSKKGSEEFFKFFKIEDQVVQTFLSSKMHIPLGQNDAGEIIFLIRSNVWDPEKIPMVKLIVLIFMGLDIIINMEESQIHGIRMLIDLNDISRKSLESWAEPKLLKQWHKVVQESYPLRVKGQIFYNEPVLFDLIYELISLFMNDKMKERTFRVKNDIKKAMEKIPGLEKILPTEYNGQGGSLNECAEKWKNKFESYYKNGNPFECISVDESKRPKANSNYLTDHSDYQNKTFGTSGSFTKFE 322

The following BLAST results are available for this feature:

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Celegans
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Yeast
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Nematostella
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TTPAL	1.024e-20	28.00	alpha tocopherol transfer protein like [Source:HGN...	[more]
TTPAL	1.024e-20	28.00	alpha tocopherol transfer protein like [Source:HGN...	[more]
CLVS2	2.950e-18	25.81	clavesin 2 [Source:HGNC Symbol;Acc:HGNC:23046]	[more]
CLVS1	5.019e-18	26.01	clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139]	[more]
CLVS1	5.019e-18	26.01	clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139]	[more]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG33514	1.397e-30	27.24	gene:FBgn0053514 transcript:FBtr0091456	[more]
CG12926	9.997e-24	26.35	gene:FBgn0033437 transcript:FBtr0088502	[more]
CG33966	4.219e-23	22.96	gene:FBgn0053966 transcript:FBtr0100007	[more]
CG10657	1.179e-22	29.23	gene:FBgn0036289 transcript:FBtr0075975	[more]
CG30339	4.607e-20	26.69	gene:FBgn0050339 transcript:FBtr0088534	[more]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttpal	1.925e-21	27.91	tocopherol (alpha) transfer protein-like [Source:Z...	[more]
ttpal	1.553e-20	28.09	tocopherol (alpha) transfer protein-like [Source:Z...	[more]
clvs2	4.795e-17	24.74	clavesin 2 [Source:NCBI gene;Acc:566769]	[more]
rlbp1a	1.240e-16	27.34	retinaldehyde binding protein 1a [Source:ZFIN;Acc:...	[more]
rlbp1a	1.240e-16	27.34	retinaldehyde binding protein 1a [Source:ZFIN;Acc:...	[more]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttpal	3.590e-26	29.23	tocopherol (alpha) transfer protein-like [Source:N...	[more]
thg1l	7.885e-19	27.34	tRNA-histidine guanylyltransferase 1-like [Source:...	[more]
clvs1	1.461e-18	24.91	clavesin 1 [Source:NCBI gene;Acc:100037913]	[more]
clvs1	4.884e-18	25.44	clavesin 1 [Source:NCBI gene;Acc:100037913]	[more]
rlbp1	3.553e-17	24.05	retinaldehyde binding protein 1 [Source:NCBI gene;...	[more]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ttpal	1.719e-20	28.19	tocopherol (alpha) transfer protein-like [Source:M...	[more]
Ttpal	1.719e-20	28.19	tocopherol (alpha) transfer protein-like [Source:M...	[more]
Clvs2	2.251e-18	26.06	clavesin 2 [Source:MGI Symbol;Acc:MGI:2443223]	[more]
Clvs1	6.270e-18	26.01	clavesin 1 [Source:MGI Symbol;Acc:MGI:1921688]	[more]
Clvs1	6.270e-18	26.01	clavesin 1 [Source:MGI Symbol;Acc:MGI:1921688]	[more]

BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9BTX7\|TTPAL_HUMAN	4.916e-20	28.00	Alpha-tocopherol transfer protein-like OS=Homo sap...	[more]
sp\|Q5RFR0\|TTPAL_PONAB	5.417e-20	28.00	Alpha-tocopherol transfer protein-like OS=Pongo ab...	[more]
sp\|Q9D3D0\|TTPAL_MOUSE	1.202e-19	28.19	Alpha-tocopherol transfer protein-like OS=Mus musc...	[more]
sp\|Q95KF7\|CLVS2_MACFA	1.417e-17	25.81	Clavesin-2 OS=Macaca fascicularis OX=9541 GN=CLVS2...	[more]
sp\|Q5SYC1\|CLVS2_HUMAN	1.417e-17	25.81	Clavesin-2 OS=Homo sapiens OX=9606 GN=CLVS2 PE=1 S...	[more]

BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4E0RHZ7	2.466e-76	38.61	Alpha-tocopherol transfer protein OS=Fasciola hepa...	[more]
A0A504YET3	1.270e-74	37.92	CRAL-TRIO domain-containing protein OS=Fasciola gi...	[more]
A0A267DVC9	4.436e-72	39.01	CRAL-TRIO domain-containing protein OS=Macrostomum...	[more]
A0A267GCN2	4.784e-72	39.01	CRAL-TRIO domain-containing protein OS=Macrostomum...	[more]
A0A1I8IZU0	1.301e-71	39.01	CRAL-TRIO domain-containing protein OS=Macrostomum...	[more]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttpal	2.779e-21	28.29	alpha tocopherol transfer protein like [Source:NCB...	[more]
ttpal	2.787e-21	28.29	alpha tocopherol transfer protein like [Source:NCB...	[more]
clvs2	6.360e-17	24.91	clavesin 2 [Source:NCBI gene;Acc:103047212]	[more]
clvs2	1.222e-16	24.56	clavesin 2 [Source:NCBI gene;Acc:103047212]	[more]
ttpa	4.127e-15	27.67	tocopherol (alpha) transfer protein [Source:ZFIN;A...	[more]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ttpal	2.909e-25	30.09	tocopherol (alpha) transfer protein-like [Source:Z...	[more]
ENSPMAT00000003570.1	7.097e-17	29.02	pep scaffold:Pmarinus_7.0:GL486699:2092:8510:1 gen...	[more]
ENSPMAT00000007468.1	1.690e-15	31.03	pep scaffold:Pmarinus_7.0:GL477833:5549:9144:1 gen...	[more]
ENSPMAT00000001440.1	6.883e-6	37.29	pep scaffold:Pmarinus_7.0:GL476337:1030926:1032713...	[more]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO33762	1.520e-8	25.15	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttpal	1.830e-22	27.99	alpha tocopherol transfer protein like [Source:NCB...	[more]
CLVS1	8.823e-19	26.50	clavesin-1 [Source:NCBI gene;Acc:101158238]	[more]
clvs2	3.341e-16	24.39	clavesin 2 [Source:NCBI gene;Acc:101159632]	[more]
ENSORLT00000002803.2	7.630e-14	26.58	retinaldehyde-binding protein 1-like [Source:NCBI ...	[more]
TTPA	1.078e-13	24.24	alpha tocopherol transfer protein [Source:NCBI gen...	[more]

BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000009988.1	0.000e+0	100.00	SMESG000009988.1	[more]
SMESG000009876.1	5.138e-122	47.83	SMESG000009876.1	[more]
SMESG000009878.1	5.079e-118	48.91	SMESG000009878.1	[more]
SMESG000009877.1	7.120e-118	47.06	SMESG000009877.1	[more]
SMESG000009872.1	2.575e-117	47.20	SMESG000009872.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034257 ID=SMED30034257|Name=CRAL-TRIO domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1138bp
CTTCCGATCTAGAGCACATTTAGTTGGCAATTAATCAATCAAACAGAAAA
TCAACTGATTGGTGTAAATCATAGATTTTGCCGTATAAATCTGAAAGACT
TTCTGCAAACATTCAAACAATCAAAAATGGCAGATACGTACACTTATGAC
GGTTTGACTGACAGAGATAAACAGGTGGCCTTGACCGAACTGAATGAAGA
TCCTAAACAAGTCAATGCGCACATTGAGAGCTTCCGTCGATGGGTCAAAT
CAATGCCCCACCTGAACTGTCCAACGGATTCAAGGTTCCTTCTCATGTTT
TTGCGGGTAGCGAAATTTGATCACGCGAAAGCCCAGAAGCGATTGGATAA
TTTTTGCACAGTTAGATCATCCGCAAGAGGCCATCCTGAGTACTTCCAGT
TTCCAGATATCAATGATGCAGTTTTCGAAAAATTCTTTCAAACAAAACAA
ATGATTCCATTAGGACGAACTGTGGATGGAGAAACGCTGTTCTTTGGAGT
TTCGAACTTATGGAATCCAAAAGAAATACCTATAAAGAAGTTAATGCAAG
TCATGTTCATGTCTTTGGAGGTCCAACTACAAAATCAGTACTTGCAAATA
TATGGAATGAAAGCTTTCATGGACATGCATGGTTGCGGGAAAAGTTTTAT
GGAAGCTGTTAGTGATCCTAAAGTTATGAAAGCTATGACTCGGGTGTGGC
AGGACTGCTACCCCATTAGATTCAAAGGCCAAGTGATTTACCGGGAGCCT
GGATGGTATAGTGTCTTTTACAATATTATGGAATTTTTTCTCAATGAAAA
ACACCGTAAACGAGTTTTCAGAATTAAGGAGGATATACAGAAAGGTTTTG
AAAAAATTCCCGGCCTTGAAGCTCTACTTCCAGAGGAATATGGTGGCAAA
GGTCCAAAGATGGATGAGGCTATTGATAAATGGGCAAAAGAGGTTCGAGA
CTTTTATACTAAAGGCTCACCGTGGGCAAATATTTCCGTTGATGAAAGTA
AAAGGCCCGTGGAAACATTAAAATACTTCGAACAATATGCGGATTACACT
GGAGAGAGTCTTGGAACAAAAGGAACATTTACAAAATTCGATGCCTTCTG
AAATGCTATGAATGAAACCATTCTCAATTGAGAGGCGC

protein sequence of SMED30034257-orf-1

>SMED30034257-orf-1 ID=SMED30034257-orf-1|Name=SMED30034257-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=325bp
MADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPT
DSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVF
EKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQ
LQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFK
GQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEAL
LPEEYGGKGPKMDEAIDKWAKEVRDFYTKGSPWANISVDESKRPVETLKY
FEQYADYTGESLGTKGTFTKFDAF*

Aliases

The feature 'CRAL-TRIO domain-containing protein' has the following synonyms


Synonym
H.93.2a
clavesin*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000035	Category 3 cell
PLANA:0000429	neoblast
PLANA:0002032	epidermal cell
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR001071	CRAL-bd_toc_tran
IPR001251	CRAL-TRIO_dom
IPR011074	CRAL/TRIO_N_dom

Vocabulary: **biological process**
Term	Definition
GO:0006810	transport

Vocabulary: **cellular component**
Term	Definition
GO:0005622	intracellular

Vocabulary: **molecular function**
Term	Definition
GO:0005215	transporter activity

Main menu

CRAL-TRIO domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Owlery

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