calreticulin-1

Overview


Name	calreticulin-1 (AFJ24760.1)
Smed ID	SMED30034254
Length (bp)	1429

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of calreticulin-1 (SMED30034254) t-SNE clustered cells

Violin plots show distribution of expression levels for calreticulin-1 (SMED30034254) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of calreticulin-1 (SMED30034254) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for calreticulin-1 (SMED30034254) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034254

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 29

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30034254	h1SMcG0014569	Contig3842	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30034254	h1SMcG0020710	Contig3842	GPL15192	PMID:23079596 Forsthoefel et al., 2012
pharynx	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30034254	h1SMcG0014569	dd_Smed_v4_220_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034254	h1SMcG0014569	Contig39273	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034254	h1SMcG0014569	Contig39273	newmark_ests	PMID:29674431 Fincher et al., 2018
Category 2 cell	SMED30034254	h1SMcG0011264	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30034254	h1SMcG0011264	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 3 cell	SMED30034254	h1SMcG0011264	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
progenitor cell	SMED30034254	h1SMcG0011264	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30034254	h1SMcG0011264	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
muscle progenitor cell	SMED30034254	h1SMcG0011264	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
secretory system	SMED30034254	h1SMcG0011264	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 2 cell	SMED30034254	h1SMcG0014569	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30034254	h1SMcG0014569	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 3 cell	SMED30034254	h1SMcG0014569	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
progenitor cell	SMED30034254	h1SMcG0014569	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30034254	h1SMcG0014569	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
muscle progenitor cell	SMED30034254	h1SMcG0014569	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
secretory system	SMED30034254	h1SMcG0014569	dd_Smed_v6_220_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of calreticulin-1 vs. Ensembl Human
Match: CALR (calreticulin [Source:HGNC Symbol;Acc:HGNC:1455])

HSP 1 Score: 432.18 bits (1110), Expect = 9.279e-149
Identity = 226/347 (65.13%), Postives = 270/347 (77.81%), Query Frame = 3

Query:  132 DPTIYLKEEFSTADS-LKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            +P +Y KE+F   D    +W+ES +K SD GKF+ ++GKFY D +KDKG+QTSQDA+FY +S   E PFSNK +TLVVQF VKHEQ IDCGGGY+KL    LDQ + HG++ Y IMFGPDICG GTKKVHVIFNY GKN LI KDI CKDDEF+HLYTLI++ DNTYEV ID  +VESG+ EDDWDFL PKKI DP+A KP DW +  K+ D  D KPEDWDKP+ IPDP AKKPEDWD+EMDGEWE P I NPEY+G+WKP++IDNP+YKG W+HPEIDNP+Y PD ++Y     G +G DLWQVKSGTIFDN LIT++  YA++FG +TW VT   EK MK+K D
Sbjct:   18 EPAVYFKEQFLDGDGWTSRWIESKHK-SDFGKFVLSSGKFYGDEEKDKGLQTSQDARFYALSASFE-PFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362

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BLAST of calreticulin-1 vs. Ensembl Human
Match: CALR3 (calreticulin 3 [Source:HGNC Symbol;Acc:HGNC:20407])

HSP 1 Score: 269.24 bits (687), Expect = 1.854e-85
Identity = 163/359 (45.40%), Postives = 219/359 (61.00%), Query Frame = 3

Query:   87 MYYILVILFSAIV--NADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAM 1154
            M   LV L++  +   A  T+Y +EEF   +  + +W++ST   S  G F  ++GKFY   +KDKG+QT+Q+ +FY IS +  KPFSNK +TLV+Q+ VKHEQ +DCGGGYIK+   D+DQKN +G++ Y IMFGPDICG   KKVHVI ++  K H  KK I CK D F+HLYTLIL+ D +Y+V ID + +ESG+ E DW+    KK   P   K  DW          D K +DW+K     D    K  DW+ ++DG+W AP +  P Y+   KP+ I    +K  W+H ++ N DY     L     IG +G +LWQV+SGTIFDN LITD+ EYA +FG  TW  T   E+ M
Sbjct:    1 MARALVQLWAICMLRVALATVYFQEEFLDGEHWRNRWLQST-NDSRFGHFRLSSGKFYGHKEKDKGLQTTQNGRFYAISARF-KPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPADIDQKNLNGKSQYYIMFGPDICGFDIKKVHVILHFKNKYHENKKLIRCKVDGFTHLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESK--DW------EQTKDNKAQDWEKH--FLDASTSKQSDWNGDLDGDWPAPMLQKPPYQDGLKPEGI----HKDVWLHRKMKNTDYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYADNFGKATWGETKGPEREM 343

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BLAST of calreticulin-1 vs. Ensembl Human
Match: CALR (calreticulin [Source:HGNC Symbol;Acc:HGNC:1455])

HSP 1 Score: 236.884 bits (603), Expect = 8.416e-75
Identity = 128/183 (69.95%), Postives = 148/183 (80.87%), Query Frame = 3

Query:  480 GPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVG 1028
            GPDICG GTKKVHVIFNY GKN LI KDI CKDDEF+HLYTLI++ DNTYEV ID  +VESG+ EDDWDFL PKKI DP+A KP DW +  K+ D  D KPEDWDKP+ IPDP AKKPEDWD+EMDGEWE P I NPEY+G+WKP++IDNP+YKG W+HPEIDNP+Y PD ++Y     G +G
Sbjct:   65 GPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLG 247

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BLAST of calreticulin-1 vs. Ensembl Human
Match: CLGN (calmegin [Source:HGNC Symbol;Acc:HGNC:2060])

HSP 1 Score: 194.897 bits (494), Expect = 5.518e-55
Identity = 141/388 (36.34%), Postives = 197/388 (50.77%), Query Frame = 3

Query:  141 IYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYD-------DMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGK--DLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNG-------KNHLIKKDIPCK---DDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDW--DFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDK---------------------PKTIPDPKAKKPXXXXXXXXXXXXAPKI-----------------DNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWR 1127
            +Y  E F +   L  WV S  K  D  + I      ++        +  D+G+     AK + IS  L KPF   D+ L+VQ++V  +  IDCGG YIKL+    DL  +NF+ +T Y IMFGPD CG    K+H IF +         + H    D+  K    D  +HLYTL++  D+T+EVL+D   V  G+  +D       PK+I DPN +KP +W +  K+PD +  KPEDWD+                     PK IPDP A+KP+DW+++ DGEWEAP+I                 DNP+Y+G W+P  +DNPNY+G W   +I NPDY  D+  +L      +G +LW + S   FDN +I  E E A  +    WR
Sbjct:   60 VYFAETFDSG-RLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMFGPDKCG-EDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTSDIYFDNFIICSEKEVADHWAADGWR 445

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Query:  141 IYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYD-------DMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGK--DLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNG-------KNHLIKKDIPCK---DDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDW--DFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDK---------------------PKTIPDPKAKKPXXXXXXXXXXXXAPKI-----------------DNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWR 1127
            +Y  E F +   L  WV S  K  D  + I      ++        +  D+G+     AK + IS  L KPF   D+ L+VQ++V  +  IDCGG YIKL+    DL  +NF+ +T Y IMFGPD CG    K+H IF +         + H    D+  K    D  +HLYTL++  D+T+EVL+D   V  G+  +D       PK+I DPN +KP +W +  K+PD +  KPEDWD+                     PK IPDP A+KP+DW+++ DGEWEAP+I                 DNP+Y+G W+P  +DNPNY+G W   +I NPDY  D+  +L      +G +LW + S   FDN +I  E E A  +    WR
Sbjct:   60 VYFAETFDSG-RLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMFGPDKCG-EDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTSDIYFDNFIICSEKEVADHWAADGWR 445

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BLAST of calreticulin-1 vs. Ensembl Celegans
Match: crt-1 (Calreticulin [Source:UniProtKB/Swiss-Prot;Acc:P27798])

HSP 1 Score: 390.963 bits (1003), Expect = 2.583e-133
Identity = 206/333 (61.86%), Postives = 254/333 (76.28%), Query Frame = 3

Query:   87 MYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITD 1085
            M  + ++   A+V+A+  +Y KEEF+ A   K+WV+S +K  D G F  +AGKF+D   +D+GIQTSQDAKFY  + K +K FSNK +TLV+Q+ VKHEQ IDCGGGY+K+M  D D  +FHGETPY +MFGPDICG  T++VHVI NY G+N LIKK+I CK DE +HLYTLIL SDNTYEV ID E  ++G+ E+DWD L  KKI DP+A+KP DW +   + D  D KPEDW+KP+ IPDP AKKPEDWDDEMDGEWE P IDNPEY+G+WKPK+I NP YKG W+HPEI+NP+Y PD+ LY     G +GFDLWQVKSGTIFDNI+ITD
Sbjct:    1 MKSLCLLAIVAVVSAE--VYFKEEFNDASWEKRWVQSKHK-DDFGAFKLSAGKFFDVESRDQGIQTSQDAKFYSRAAKFDKDFSNKGKTLVIQYTVKHEQGIDCGGGYVKVMRADADLGDFHGETPYNVMFGPDICG-PTRRVHVILNYKGENKLIKKEITCKSDELTHLYTLILNSDNTYEVKIDGESAQTGSLEEDWDLLPAKKIKDPDAKKPEDWDEREYIDDAEDAKPEDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIKNPAYKGKWIHPEIENPEYTPDDELYSYESWGAIGFDLWQVKSGTIFDNIIITD 329

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Query:   87 MYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITD 1085
            M  + ++   A+V+A+  +Y KEEF+ A   K+WV+S +K  D G F  +AGKF+D   +D+GIQTSQDAKFY  + K +K FSNK +TLV+Q+ VKHEQ IDCGGGY+K+M  D D  +FHGETPY +MFGPDICG  T++VHVI NY G+N LIKK+I CK DE +HLYTLIL SDNTYEV ID E  ++G+ E+DWD L  KKI DP+A+KP DW +   + D  D KPEDW+KP+ IPDP AKKPEDWDDEMDGEWE P IDNPEY+G+WKPK+I NP YKG W+HPEI+NP+Y PD+ LY     G +GFDLWQVKSGTIFDNI+ITD
Sbjct:    1 MKSLCLLAIVAVVSAE--VYFKEEFNDASWEKRWVQSKHK-DDFGAFKLSAGKFFDVESRDQGIQTSQDAKFYSRAAKFDKDFSNKGKTLVIQYTVKHEQGIDCGGGYVKVMRADADLGDFHGETPYNVMFGPDICG-PTRRVHVILNYKGENKLIKKEITCKSDELTHLYTLILNSDNTYEVKIDGESAQTGSLEEDWDLLPAKKIKDPDAKKPEDWDEREYIDDAEDAKPEDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIKNPAYKGKWIHPEIENPEYTPDDELYSYESWGAIGFDLWQVKSGTIFDNIIITD 329

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BLAST of calreticulin-1 vs. Ensembl Celegans
Match: cnx-1 (Calnexin [Source:UniProtKB/Swiss-Prot;Acc:P34652])

HSP 1 Score: 168.318 bits (425), Expect = 1.418e-45
Identity = 125/345 (36.23%), Postives = 171/345 (49.57%), Query Frame = 3

Query:  258 MDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLM--GKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNY----NGKNHLIKKDIPCK------DDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWD--FLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWD-------------KP--------KTIPDPKAKKPXXXXXXXXXXXXAPKIDN-------------------PEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRV 1130
            ++ D G+     A+ + I+ KL  PF+    T VVQ+ +K E+  +CGGGY+KL+  G + D  NF  +T Y IMFGPD CG  T KVH+IF Y    NG       + P        DD  +HL+TL++K    Y V +D + +  GN   D       PK+I D    KP DW +   + DE+  KP+DWD             KP        + I DP+AKKP+DWD++MDG WEAP IDN                   P+Y+G W   +I NP +KG W    IDNP+Y           I  VG ++W +    +FDNILIT   E + D   +T+ V
Sbjct:  106 IEGDLGLIVKTKARHHAIAAKLNTPFAFDANTFVVQYDIKFEEGQECGGGYLKLLSEGAEKDLANFQDKTAYTIMFGPDKCG-ATGKVHLIFRYKNPINGTISEYHANQPTTIGSTYWDDHNTHLFTLVVKPTGEYSVSVDGKSLYYGNMMSDVTPALTPPKQIFDETDLKPVDWDERENIEDESAVKPDDWDENEPQSVVDEAATKPYDWNEEENELIADPEAKKPQDWDEDMDGSWEAPLIDNPACKGLSGCGTWKAPTIKNPKYKGKWIRPKISNPAFKGKWTARLIDNPNYFEPKPFAGLAPITAVGIEMWTMSENILFDNILITSSEEDSSDVAKQTFYV 449

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BLAST of calreticulin-1 vs. Ensembl Celegans
Match: cnx-1 (Calnexin [Source:UniProtKB/Swiss-Prot;Acc:P34652])

HSP 1 Score: 113.235 bits (282), Expect = 4.779e-27
Identity = 97/271 (35.79%), Postives = 128/271 (47.23%), Query Frame = 3

Query:  474 MFGPDICGIGTKKVHVIFNY----NGKNHLIKKDIPCK------DDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWD--FLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWD-------------KP--------KTIPDPKAKKPXXXXXXXXXXXXAPKIDN-------------------PEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRV 1130
            MFGPD CG  T KVH+IF Y    NG       + P        DD  +HL+TL++K    Y V +D + +  GN   D       PK+I D    KP DW +   + DE+  KP+DWD             KP        + I DP+AKKP+DWD++MDG WEAP IDN                   P+Y+G W   +I NP +KG W    IDNP+Y           I  VG ++W +    +FDNILIT   E + D   +T+ V
Sbjct:    1 MFGPDKCG-ATGKVHLIFRYKNPINGTISEYHANQPTTIGSTYWDDHNTHLFTLVVKPTGEYSVSVDGKSLYYGNMMSDVTPALTPPKQIFDETDLKPVDWDERENIEDESAVKPDDWDENEPQSVVDEAATKPYDWNEEENELIADPEAKKPQDWDEDMDGSWEAPLIDNPACKGLSGCGTWKAPTIKNPKYKGKWIRPKISNPAFKGKWTARLIDNPNYFEPKPFAGLAPITAVGIEMWTMSENILFDNILITSSEEDSSDVAKQTFYV 270

[Close]

BLAST of calreticulin-1 vs. Ensembl Fly
Match: Calr (gene:FBgn0005585 transcript:FBtr0334618)

HSP 1 Score: 435.261 bits (1118), Expect = 1.721e-150
Identity = 232/363 (63.91%), Postives = 270/363 (74.38%), Query Frame = 3

Query:   84 MMYYILVILFSAIVN-ADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            MM+   VI+  A V      +YLKE F   +    W+ S + G + GKF+ T G FY+D + DKGIQTSQDA+FY  S K +  FSN+D+ LVVQF VKHEQ IDCGGGY+KL    LDQ + HGE+PYEIMFGPDICG GTKKVHVIF+Y GKNHLI KDI CKDD ++H YTLI++ DNTYEVLID EKVESGN EDDWDFL PKKI DP A KP DW D   +PD +DKKPEDWDKP+ IPDP A KPEDWDDEMDGEWE P IDNPE++G+W+PK++DNPNYKG W HPEI NP+Y PD+ LYLR EI  +GFDLWQVKSGTIFDN+LITD+ E A     +  + T  GEK MK   D
Sbjct:    1 MMWCKTVIVLLATVGFISAEVYLKENFDNENWEDTWIYSKHPGKEFGKFVLTPGTFYNDAEADKGIQTSQDARFYAASRKFDG-FSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCSLDQTDMHGESPYEIMFGPDICGPGTKKVHVIFSYKGKNHLISKDIRCKDDVYTHFYTLIVRPDNTYEVLIDNEKVESGNLEDDWDFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDWDKPEHIPDPDATKPEDWDDEMDGEWEPPMIDNPEFKGEWQPKQLDNPNYKGAWEHPEIANPEYVPDDKLYLRKEICTLGFDLWQVKSGTIFDNVLITDDVELAAKAAAEV-KNTQAGEKKMKEAQD 361

[Close]

BLAST of calreticulin-1 vs. Ensembl Fly
Match: Calr (gene:FBgn0005585 transcript:FBtr0082103)

HSP 1 Score: 435.261 bits (1118), Expect = 1.721e-150
Identity = 232/363 (63.91%), Postives = 270/363 (74.38%), Query Frame = 3

Query:   84 MMYYILVILFSAIVN-ADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            MM+   VI+  A V      +YLKE F   +    W+ S + G + GKF+ T G FY+D + DKGIQTSQDA+FY  S K +  FSN+D+ LVVQF VKHEQ IDCGGGY+KL    LDQ + HGE+PYEIMFGPDICG GTKKVHVIF+Y GKNHLI KDI CKDD ++H YTLI++ DNTYEVLID EKVESGN EDDWDFL PKKI DP A KP DW D   +PD +DKKPEDWDKP+ IPDP A KPEDWDDEMDGEWE P IDNPE++G+W+PK++DNPNYKG W HPEI NP+Y PD+ LYLR EI  +GFDLWQVKSGTIFDN+LITD+ E A     +  + T  GEK MK   D
Sbjct:    1 MMWCKTVIVLLATVGFISAEVYLKENFDNENWEDTWIYSKHPGKEFGKFVLTPGTFYNDAEADKGIQTSQDARFYAASRKFDG-FSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCSLDQTDMHGESPYEIMFGPDICGPGTKKVHVIFSYKGKNHLISKDIRCKDDVYTHFYTLIVRPDNTYEVLIDNEKVESGNLEDDWDFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDWDKPEHIPDPDATKPEDWDDEMDGEWEPPMIDNPEFKGEWQPKQLDNPNYKGAWEHPEIANPEYVPDDKLYLRKEICTLGFDLWQVKSGTIFDNVLITDDVELAAKAAAEV-KNTQAGEKKMKEAQD 361

[Close]

BLAST of calreticulin-1 vs. Ensembl Fly
Match: Cnx99A (gene:FBgn0015622 transcript:FBtr0085438)

HSP 1 Score: 176.407 bits (446), Expect = 1.466e-48
Identity = 139/387 (35.92%), Postives = 196/387 (50.65%), Query Frame = 3

Query:  171 DSLKKWVESTYKGSDQGKFIYTAGKFYD-------DMDKDKGIQTSQDAKFYGISYKLEKPFSNK-DRTLVVQFQVKHEQTIDCGGGYIKLM--GKDLDQ-KNFHGETPYEIMFGPDICGIGTKKVHVIFNY----NG----------KNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWD--FLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDK---------------------PKTIPDPKAKKPXXXXXXXXXXXXAPKIDNP-------------------EYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRV 1130
            +S K+WV S  K  D  + I      ++           D G+     AK   I+  L KPF  K D+ LVVQ++V  ++  +CGG Y+KL+  GKD +Q K F+ +TPY IMFGPD CG    K+H IF +    NG          KN L   + P KD +  HLY L+++ DN++E+ +D + +  G+   D+      P +I+DPN  KP  W +  K+PD    KPEDWD+                     P  I DP A KPEDWD E+DGEWEAP +DNP                    Y+G W+   I+NPNY+G W   +I NPD+  D   +    I  VG +LW + S  +FDN++ITD+ E A+DF   ++ +
Sbjct:   83 ESRKRWVLSQAKKDDIAEEISKYDGIWNWESPQRIVWANDLGLVLKSKAKHAAIAAPLRKPFEFKSDKPLVVQYEVTLQEGQECGGSYLKLLSAGKDTEQLKAFNDKTPYTIMFGPDKCG-NDVKMHFIFRHVNPINGTITEKHCNKPKNRL---EEPFKD-KLPHLYQLVVRPDNSFEIRVDHKIINEGSLLTDFKPPVNPPAEIDDPNDHKPESWDEREKIPDPTAHKPEDWDEDAPPQLPDTDAVMPNGWLEDEPDMIFDPTATKPEDWDAEIDGEWEAPLVDNPVCEKAPGCGKWKAPLIPNPNYKGKWRAPMIENPNYQGKWAPRKIPNPDFFEDLKPFQMTPISAVGLELWSMSSDILFDNLIITDDVEVARDFAANSFDI 464

[Close]

BLAST of calreticulin-1 vs. Ensembl Fly
Match: Cnx99A (gene:FBgn0015622 transcript:FBtr0085437)

HSP 1 Score: 176.407 bits (446), Expect = 1.466e-48
Identity = 139/387 (35.92%), Postives = 196/387 (50.65%), Query Frame = 3

Query:  171 DSLKKWVESTYKGSDQGKFIYTAGKFYD-------DMDKDKGIQTSQDAKFYGISYKLEKPFSNK-DRTLVVQFQVKHEQTIDCGGGYIKLM--GKDLDQ-KNFHGETPYEIMFGPDICGIGTKKVHVIFNY----NG----------KNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWD--FLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDK---------------------PKTIPDPKAKKPXXXXXXXXXXXXAPKIDNP-------------------EYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRV 1130
            +S K+WV S  K  D  + I      ++           D G+     AK   I+  L KPF  K D+ LVVQ++V  ++  +CGG Y+KL+  GKD +Q K F+ +TPY IMFGPD CG    K+H IF +    NG          KN L   + P KD +  HLY L+++ DN++E+ +D + +  G+   D+      P +I+DPN  KP  W +  K+PD    KPEDWD+                     P  I DP A KPEDWD E+DGEWEAP +DNP                    Y+G W+   I+NPNY+G W   +I NPD+  D   +    I  VG +LW + S  +FDN++ITD+ E A+DF   ++ +
Sbjct:   83 ESRKRWVLSQAKKDDIAEEISKYDGIWNWESPQRIVWANDLGLVLKSKAKHAAIAAPLRKPFEFKSDKPLVVQYEVTLQEGQECGGSYLKLLSAGKDTEQLKAFNDKTPYTIMFGPDKCG-NDVKMHFIFRHVNPINGTITEKHCNKPKNRL---EEPFKD-KLPHLYQLVVRPDNSFEIRVDHKIINEGSLLTDFKPPVNPPAEIDDPNDHKPESWDEREKIPDPTAHKPEDWDEDAPPQLPDTDAVMPNGWLEDEPDMIFDPTATKPEDWDAEIDGEWEAPLVDNPVCEKAPGCGKWKAPLIPNPNYKGKWRAPMIENPNYQGKWAPRKIPNPDFFEDLKPFQMTPISAVGLELWSMSSDILFDNLIITDDVEVARDFAANSFDI 464

[Close]

BLAST of calreticulin-1 vs. Ensembl Fly
Match: Cnx99A (gene:FBgn0015622 transcript:FBtr0110909)

HSP 1 Score: 176.407 bits (446), Expect = 1.466e-48
Identity = 139/387 (35.92%), Postives = 196/387 (50.65%), Query Frame = 3

Query:  171 DSLKKWVESTYKGSDQGKFIYTAGKFYD-------DMDKDKGIQTSQDAKFYGISYKLEKPFSNK-DRTLVVQFQVKHEQTIDCGGGYIKLM--GKDLDQ-KNFHGETPYEIMFGPDICGIGTKKVHVIFNY----NG----------KNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWD--FLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDK---------------------PKTIPDPKAKKPXXXXXXXXXXXXAPKIDNP-------------------EYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRV 1130
            +S K+WV S  K  D  + I      ++           D G+     AK   I+  L KPF  K D+ LVVQ++V  ++  +CGG Y+KL+  GKD +Q K F+ +TPY IMFGPD CG    K+H IF +    NG          KN L   + P KD +  HLY L+++ DN++E+ +D + +  G+   D+      P +I+DPN  KP  W +  K+PD    KPEDWD+                     P  I DP A KPEDWD E+DGEWEAP +DNP                    Y+G W+   I+NPNY+G W   +I NPD+  D   +    I  VG +LW + S  +FDN++ITD+ E A+DF   ++ +
Sbjct:   83 ESRKRWVLSQAKKDDIAEEISKYDGIWNWESPQRIVWANDLGLVLKSKAKHAAIAAPLRKPFEFKSDKPLVVQYEVTLQEGQECGGSYLKLLSAGKDTEQLKAFNDKTPYTIMFGPDKCG-NDVKMHFIFRHVNPINGTITEKHCNKPKNRL---EEPFKD-KLPHLYQLVVRPDNSFEIRVDHKIINEGSLLTDFKPPVNPPAEIDDPNDHKPESWDEREKIPDPTAHKPEDWDEDAPPQLPDTDAVMPNGWLEDEPDMIFDPTATKPEDWDAEIDGEWEAPLVDNPVCEKAPGCGKWKAPLIPNPNYKGKWRAPMIENPNYQGKWAPRKIPNPDFFEDLKPFQMTPISAVGLELWSMSSDILFDNLIITDDVEVARDFAANSFDI 464

[Close]

BLAST of calreticulin-1 vs. Ensembl Zebrafish
Match: calr (calreticulin [Source:ZFIN;Acc:ZDB-GENE-030131-4042])

HSP 1 Score: 429.869 bits (1104), Expect = 5.044e-148
Identity = 219/358 (61.17%), Postives = 276/358 (77.09%), Query Frame = 3

Query:   87 MYYILVILFSAIVNADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMK 1157
            +  + + +  A++ A+  +Y +E+F   DS + +WVES +K +D GKF+ +AGKFY D +KDKG+QTSQDA FY +S +    F+NKD+ LV+QF VKHEQ IDCGGGYIKL   DL+Q++ HG++ Y IMFGPDICG GTKKVHVIFNY GKNHLI KDI CKDDE+SHLYTLI+  DNTYEV ID +KVESG+ E+DWDFL  KKI DP A+KP DW +  K+ D  D+KPE+WDKP+ IPDP AKKP+DWD+EMDGEWE P + NP+Y+G+WKP++IDNP YKG WVHPEIDNP+Y  D+ +Y    IG +G DLWQVKSGTIFDN LIT++P+ A++ G +TW  T D EK MK
Sbjct:    4 LSLLFMAVSVALITAESNVYFREQFEDGDSWRSRWVESKHK-TDYGKFVLSAGKFYGDAEKDKGLQTSQDAHFYAMSARF-GDFNNKDQPLVIQFSVKHEQNIDCGGGYIKLFPSDLNQEDMHGDSTYNIMFGPDICGPGTKKVHVIFNYKGKNHLINKDIRCKDDEYSHLYTLIVNPDNTYEVKIDNKKVESGSLEEDWDFLPSKKIKDPEAKKPEDWDEREKIDDPEDQKPEEWDKPENIPDPDAKKPDDWDEEMDGEWEPPMVTNPDYKGEWKPRQIDNPAYKGKWVHPEIDNPEYTADSEIYKYDSIGVIGLDLWQVKSGTIFDNFLITNDPKLAEEVGTETWGATKDAEKKMK 359

[Close]

BLAST of calreticulin-1 vs. Ensembl Zebrafish
Match: calr3a (calreticulin 3a [Source:ZFIN;Acc:ZDB-GENE-000208-17])

HSP 1 Score: 416.772 bits (1070), Expect = 6.952e-143
Identity = 223/362 (61.60%), Postives = 268/362 (74.03%), Query Frame = 3

Query:   84 MMYYILVILFSAIVN-ADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNK 1163
            M     V   SA+   A   +Y KE+F   D  K +WVES +K SD G++  T+GKFY D + DKG+QTSQDA+FY +S + +  FSN+ +TLV+QF VKHEQ IDCGGGY+K+   ++DQ   HGE+ Y IMFGPDICG  TKKVHVIFNY G+NHLIKKDI CKDDE +HLYTLIL+ D TYEV ID EKVESG+ E+DWDFL PKKI DP A+KP DW D  K+ D  D KPEDWDKP+ IPDP AKKP+DWD++MDGEWE   I NPEY+G+WKPK+IDNP+YKG WVHPEIDNP+Y  D+ +Y    IG +G DLWQVKSGTIFDN LITD+ E A+ FG  TW  T   EK MK++
Sbjct:    1 MRITAAVCFISALAFIAHADVYFKEQFLDGDGWKSRWVESKHK-SDYGQWKLTSGKFYGDAELDKGLQTSQDARFYALSSRFDS-FSNEGKTLVIQFTVKHEQKIDCGGGYVKVFPAEMDQTEMHGESQYYIMFGPDICGYSTKKVHVIFNYKGQNHLIKKDIKCKDDELTHLYTLILRPDQTYEVKIDNEKVESGSLEEDWDFLPPKKIKDPEAKKPDDWDDRAKIDDPEDTKPEDWDKPENIPDPDAKKPDDWDEDMDGEWEPAMIPNPEYKGEWKPKQIDNPSYKGTWVHPEIDNPEYAADDAIYKFDSIGVLGLDLWQVKSGTIFDNFLITDDVEEAEKFGTDTWGATKGPEKKMKDQ 360

[Close]

BLAST of calreticulin-1 vs. Ensembl Zebrafish
Match: calr3b (calreticulin 3b [Source:ZFIN;Acc:ZDB-GENE-030131-9907])

HSP 1 Score: 413.69 bits (1062), Expect = 1.054e-141
Identity = 216/332 (65.06%), Postives = 259/332 (78.01%), Query Frame = 3

Query:  141 IYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVT 1133
            +YL E+F   D+ + +WV S +K SD G+F  TAG FY D +KDKG+QTSQDA+FY  S + E PFSN+ +TLV+QF VKHEQ IDCGGGY+K+   DL+Q + HG++ Y IMFGPDICG  TKKVHVIFNY G+NHLIKKDI CKDDE +HLYTLIL  D TYEV ID EKVESG+ E+DWDFL PKKI DP A+KP DW D  K+ DE D KPEDWDKP+ IPDP AKKPEDWD++MDGEWE   I NPEY+G+WKPK+IDNPNYKG WVHPEIDNP++ PD+ +Y    IG +G DLWQVKSGTIFDN  I+D+ + A++FG +TW  T
Sbjct:   22 VYLNEQFLDGDAWRSRWVNSEHK-SDYGQFKLTAGNFYGDAEKDKGLQTSQDARFYATSVRFE-PFSNEGKTLVIQFTVKHEQKIDCGGGYVKVFPADLNQADMHGDSQYYIMFGPDICGYSTKKVHVIFNYKGQNHLIKKDIKCKDDELTHLYTLILNPDQTYEVKIDNEKVESGSLEEDWDFLPPKKIKDPEAKKPEDWDDRAKIDDETDTKPEDWDKPENIPDPDAKKPEDWDEDMDGEWEPAMIPNPEYKGEWKPKQIDNPNYKGAWVHPEIDNPEHVPDDQIYKFDNIGVLGLDLWQVKSGTIFDNFFISDDVKEAEEFGNETWGAT 351

[Close]

BLAST of calreticulin-1 vs. Ensembl Zebrafish
Match: clgn (calmegin [Source:ZFIN;Acc:ZDB-GENE-060929-708])

HSP 1 Score: 186.422 bits (472), Expect = 7.577e-52
Identity = 133/340 (39.12%), Postives = 179/340 (52.65%), Query Frame = 3

Query:  267 DKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMG--KDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNY----NG---KNHLIKKDIPCK---DDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDW--DFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDK---------------------PKTIPDPKAKKPXXXXXXXXXXXXAPKI-------------------DNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTW 1124
            D G+     AK + IS  L KPF  KD+ L+VQ++V  +  IDCGG YIKL+   KDL+ + FH  TPY IMFGPD CG    K+H IF +    NG   + H  + D+  K    D+ +HL+TL+L  DN+YE  ID   V  G+   D       PK+I+DP   KP DW +  K+PD    KPE+WD+                     P+ + DP A+KP+DWD+EMDGEWEAP++                   +NP+Y+G WK   IDNPNY+G W   +I NPD+  D   +       VG +LW + S   FDN +IT E E A  +   +W
Sbjct:  118 DLGLVLKSRAKHHAISALLNKPFVFKDKPLIVQYEVNFQDGIDCGGAYIKLLSDSKDLELEQFHDRTPYSIMFGPDKCG-EDYKLHFIFRHKNPLNGDVEEKHAKRPDVDLKKIYTDKKTHLFTLVLNPDNSYETFIDQSSVSRGSLLTDVVPPVNPPKEIDDPKDSKPEDWDERAKIPDPEAVKPEEWDEEALAKVPDPDAVKPDGWLDDEPEFVSDPTAEKPDDWDEEMDGEWEAPQVPNPACTSAPGCGEWKPPMVNNPKYKGKWKAPLIDNPNYQGVWSPRKIPNPDHFEDLHPFRMEPFRAVGLELWSMTSDIYFDNFIITTEKEVADRWAADSW 456

[Close]

BLAST of calreticulin-1 vs. Ensembl Zebrafish
Match: canx (calnexin [Source:ZFIN;Acc:ZDB-GENE-040426-2797])

HSP 1 Score: 183.341 bits (464), Expect = 6.175e-51
Identity = 146/402 (36.32%), Postives = 198/402 (49.25%), Query Frame = 3

Query:  144 YLKEEFSTADSLKKWVESTYK--GSDQGKFIYTAGKFYDDMDK-----DKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGK--DLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNG-------KNHLIKKDIPCKD---DEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWD--FLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDK---------------------PKTIPDPKAKKPXXXXXXXXXXXXAPKI-------------------DNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKL 1166
            Y  E F    +L+ WV S  K  G D+    Y      ++M       DKG+     AK + IS  L +PF+   + L+VQ++V  +  IDCGG Y+KL+ +  DLD + F  +TPY IMFGPD CG    K+H IF +         + H  K D   +    D+ +HLYTL+L  DNT+E+LID   V SG+  +D       P +I DP+  KP DW + PK+ D +  KPEDWD+                     P+ I DP A KPEDWD++MDGEWEAP+I                   DNP Y+G WK   IDNPNY+G W   +I NPD+  D   +       VG +LW + S   FDN  IT +   A+ +    W +    E A +  L
Sbjct:   78 YFAEAFDKG-TLQGWVLSQAKKDGIDEDIAKYDGKWEVEEMQDSKLPGDKGLVLKSKAKHHAISALLLRPFTFDTKPLIVQYEVNFQTGIDCGGAYVKLLSQTPDLDLEEFVDKTPYTIMFGPDKCG-EDYKLHFIFRHKNPKTGEFEEKHAKKPDSDLRSYYTDKKTHLYTLVLNPDNTFEILIDQTVVNSGSLLNDVTPPVNPPAEIEDPDDHKPEDWDERPKIQDPDAVKPEDWDEDAPAKIADEDAVKPDGWLDDEPEYISDPDAVKPEDWDEDMDGEWEAPQIPNPVCETAPGCGAWERPMIDNPNYKGKWKSPMIDNPNYQGVWKPRKIPNPDFFEDLHPFRMTPFSAVGLELWSMSSDIFFDNFFITSDRNVAERWANDGWGLKKAAEGAAEPGL 477

[Close]

BLAST of calreticulin-1 vs. Ensembl Xenopus
Match: calr (calreticulin [Source:NCBI gene;Acc:407962])

HSP 1 Score: 431.795 bits (1109), Expect = 1.401e-148
Identity = 224/360 (62.22%), Postives = 278/360 (77.22%), Query Frame = 3

Query:   93 YILVILFSAIVNADPTIYLKEEFSTADSL-KKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            ++++ L +A+  ADP +YLKEEF+  D   ++WVES +K SD GKF  +AGKFY D +KDKG+QTSQDA+FY +S + +  FSNKD+TLV+QF VKHEQ IDCGGGY+KL   +L+Q   HGE+ Y IMFGPDICG  TKKVHVIF Y  KN  I KDI C+DD F+HLYTLI++ DNTYEV ID  KVESG+ E+DWDFL  KKI DP A+KP DW + PK+ D  DKKPEDWDK + IPDP A KPEDWD+EMDGEWE P I NP+Y+G+WKP++IDNP+YKG W+HPEIDNP+Y PD+TLY     G +G DLWQVKSGTIFDN L+TD+ +YA+++G +TW VT + EK MK + D
Sbjct:    6 FLILPLLAALCIADPAVYLKEEFADGDGWSQRWVESKHK-SDYGKFKLSAGKFYGDAEKDKGLQTSQDARFYALSTRFDS-FSNKDKTLVIQFSVKHEQNIDCGGGYVKLFPAELEQSEMHGESEYNIMFGPDICGPPTKKVHVIFQYKKKNLQINKDIRCRDDSFTHLYTLIVRPDNTYEVKIDNSKVESGSLEEDWDFLPAKKIKDPEAKKPDDWDERPKIDDPEDKKPEDWDKAEHIPDPDAVKPEDWDEEMDGEWEPPVIQNPDYKGEWKPRQIDNPDYKGKWIHPEIDNPEYTPDSTLYQYDSFGVLGLDLWQVKSGTIFDNFLMTDDEKYAEEYGNETWGVTKEAEKKMKEQQD 363

[Close]

BLAST of calreticulin-1 vs. Ensembl Xenopus
Match: calr (calreticulin [Source:NCBI gene;Acc:407962])

HSP 1 Score: 408.297 bits (1048), Expect = 7.030e-140
Identity = 213/332 (64.16%), Postives = 259/332 (78.01%), Query Frame = 3

Query:  174 SLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            S+ +WVES +K SD GKF  +AGKFY D +KDKG+QTSQDA+FY +S + +  FSNKD+TLV+QF VKHEQ IDCGGGY+KL   +L+Q   HGE+ Y IMFGPDICG  TKKVHVIF Y  KN  I KDI C+DD F+HLYTLI++ DNTYEV ID  KVESG+ E+DWDFL  KKI DP A+KP DW + PK+ D  DKKPEDWDK + IPDP A KPEDWD+EMDGEWE P I NP+Y+G+WKP++IDNP+YKG W+HPEIDNP+Y PD+TLY     G +G DLWQVKSGTIFDN L+TD+ +YA+++G +TW VT + EK MK + D
Sbjct:    4 SVLRWVESKHK-SDYGKFKLSAGKFYGDAEKDKGLQTSQDARFYALSTRFDS-FSNKDKTLVIQFSVKHEQNIDCGGGYVKLFPAELEQSEMHGESEYNIMFGPDICGPPTKKVHVIFQYKKKNLQINKDIRCRDDSFTHLYTLIVRPDNTYEVKIDNSKVESGSLEEDWDFLPAKKIKDPEAKKPDDWDERPKIDDPEDKKPEDWDKAEHIPDPDAVKPEDWDEEMDGEWEPPVIQNPDYKGEWKPRQIDNPDYKGKWIHPEIDNPEYTPDSTLYQYDSFGVLGLDLWQVKSGTIFDNFLMTDDEKYAEEYGNETWGVTKEAEKKMKEQQD 333

[Close]

BLAST of calreticulin-1 vs. Ensembl Xenopus
Match: calr (calreticulin [Source:NCBI gene;Acc:407962])

HSP 1 Score: 409.453 bits (1051), Expect = 1.727e-139
Identity = 217/359 (60.45%), Postives = 267/359 (74.37%), Query Frame = 3

Query:   99 LVILFSAIVNADPTIYLKEEFSTADS--LKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            +++L   I    P I      S+      ++WVES +K SD GKF  +AGKFY D +KDKG+QTSQDA+FY +S + +  FSNKD+TLV+QF VKHEQ IDCGGGY+KL   +L+Q   HGE+ Y IMFGPDICG  TKKVHVIF Y  KN  I KDI C+DD F+HLYTLI++ DNTYEV ID  KVESG+ E+DWDFL  KKI DP A+KP DW + PK+ D  DKKPEDWDK + IPDP A KPEDWD+EMDGEWE P I NP+Y+G+WKP++IDNP+YKG W+HPEIDNP+Y PD+TLY     G +G DLWQVKSGTIFDN L+TD+ +YA+++G +TW VT + EK MK + D
Sbjct:   38 MIVLCVFIACNAPVINFNLSCSSLSDGWSQRWVESKHK-SDYGKFKLSAGKFYGDAEKDKGLQTSQDARFYALSTRFDS-FSNKDKTLVIQFSVKHEQNIDCGGGYVKLFPAELEQSEMHGESEYNIMFGPDICGPPTKKVHVIFQYKKKNLQINKDIRCRDDSFTHLYTLIVRPDNTYEVKIDNSKVESGSLEEDWDFLPAKKIKDPEAKKPDDWDERPKIDDPEDKKPEDWDKAEHIPDPDAVKPEDWDEEMDGEWEPPVIQNPDYKGEWKPRQIDNPDYKGKWIHPEIDNPEYTPDSTLYQYDSFGVLGLDLWQVKSGTIFDNFLMTDDEKYAEEYGNETWGVTKEAEKKMKEQQD 394

[Close]

BLAST of calreticulin-1 vs. Ensembl Xenopus
Match: calr (calreticulin [Source:NCBI gene;Acc:407962])

HSP 1 Score: 407.142 bits (1045), Expect = 4.211e-139
Identity = 212/330 (64.24%), Postives = 258/330 (78.18%), Query Frame = 3

Query:  180 KKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            ++WVES +K SD GKF  +AGKFY D +KDKG+QTSQDA+FY +S + +  FSNKD+TLV+QF VKHEQ IDCGGGY+KL   +L+Q   HGE+ Y IMFGPDICG  TKKVHVIF Y  KN  I KDI C+DD F+HLYTLI++ DNTYEV ID  KVESG+ E+DWDFL  KKI DP A+KP DW + PK+ D  DKKPEDWDK + IPDP A KPEDWD+EMDGEWE P I NP+Y+G+WKP++IDNP+YKG W+HPEIDNP+Y PD+TLY     G +G DLWQVKSGTIFDN L+TD+ +YA+++G +TW VT + EK MK + D
Sbjct:   27 QRWVESKHK-SDYGKFKLSAGKFYGDAEKDKGLQTSQDARFYALSTRFDS-FSNKDKTLVIQFSVKHEQNIDCGGGYVKLFPAELEQSEMHGESEYNIMFGPDICGPPTKKVHVIFQYKKKNLQINKDIRCRDDSFTHLYTLIVRPDNTYEVKIDNSKVESGSLEEDWDFLPAKKIKDPEAKKPDDWDERPKIDDPEDKKPEDWDKAEHIPDPDAVKPEDWDEEMDGEWEPPVIQNPDYKGEWKPRQIDNPDYKGKWIHPEIDNPEYTPDSTLYQYDSFGVLGLDLWQVKSGTIFDNFLMTDDEKYAEEYGNETWGVTKEAEKKMKEQQD 354

[Close]

BLAST of calreticulin-1 vs. Ensembl Xenopus
Match: calr (calreticulin [Source:NCBI gene;Acc:407962])

HSP 1 Score: 407.142 bits (1045), Expect = 4.360e-139
Identity = 212/330 (64.24%), Postives = 258/330 (78.18%), Query Frame = 3

Query:  180 KKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            ++WVES +K SD GKF  +AGKFY D +KDKG+QTSQDA+FY +S + +  FSNKD+TLV+QF VKHEQ IDCGGGY+KL   +L+Q   HGE+ Y IMFGPDICG  TKKVHVIF Y  KN  I KDI C+DD F+HLYTLI++ DNTYEV ID  KVESG+ E+DWDFL  KKI DP A+KP DW + PK+ D  DKKPEDWDK + IPDP A KPEDWD+EMDGEWE P I NP+Y+G+WKP++IDNP+YKG W+HPEIDNP+Y PD+TLY     G +G DLWQVKSGTIFDN L+TD+ +YA+++G +TW VT + EK MK + D
Sbjct:   29 QRWVESKHK-SDYGKFKLSAGKFYGDAEKDKGLQTSQDARFYALSTRFDS-FSNKDKTLVIQFSVKHEQNIDCGGGYVKLFPAELEQSEMHGESEYNIMFGPDICGPPTKKVHVIFQYKKKNLQINKDIRCRDDSFTHLYTLIVRPDNTYEVKIDNSKVESGSLEEDWDFLPAKKIKDPEAKKPDDWDERPKIDDPEDKKPEDWDKAEHIPDPDAVKPEDWDEEMDGEWEPPVIQNPDYKGEWKPRQIDNPDYKGKWIHPEIDNPEYTPDSTLYQYDSFGVLGLDLWQVKSGTIFDNFLMTDDEKYAEEYGNETWGVTKEAEKKMKEQQD 356

[Close]

BLAST of calreticulin-1 vs. Ensembl Mouse
Match: Calr (calreticulin [Source:MGI Symbol;Acc:MGI:88252])

HSP 1 Score: 438.728 bits (1127), Expect = 1.699e-151
Identity = 230/347 (66.28%), Postives = 272/347 (78.39%), Query Frame = 3

Query:  132 DPTIYLKEEFSTADS-LKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            DP IY KE+F   D+   +WVES +K SD GKF+ ++GKFY D++KDKG+QTSQDA+FY +S K E PFSNK +TLVVQF VKHEQ IDCGGGY+KL    LDQK+ HG++ Y IMFGPDICG GTKKVHVIFNY GKN LI KDI CKDDEF+HLYTLI++ DNTYEV ID  +VESG+ EDDWDFL PKKI DP+A KP DW +  K+ D  D KPEDWDKP+ IPDP AKKPEDWD+EMDGEWE P I NPEY+G+WKP++IDNP+YKG W+HPEIDNP+Y PD  +Y       +G DLWQVKSGTIFDN LIT++  YA++FG +TW VT   EK MK+K D
Sbjct:   18 DPAIYFKEQFLDGDAWTNRWVESKHK-SDFGKFVLSSGKFYGDLEKDKGLQTSQDARFYALSAKFE-PFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPSGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362

[Close]

BLAST of calreticulin-1 vs. Ensembl Mouse
Match: Calr4 (calreticulin 4 [Source:MGI Symbol;Acc:MGI:2140435])

HSP 1 Score: 351.288 bits (900), Expect = 4.213e-117
Identity = 181/333 (54.35%), Postives = 241/333 (72.37%), Query Frame = 3

Query:  159 FSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMK 1157
            FST    K+WV+S ++ SD G+F   +GKFY D ++DKG+QT++DAKFY +S +  KPFSN++ TLVVQF VKHEQ IDCGGGY+KL    L+Q++ H E+ Y IMFGPDICG G  ++ VI ++ GK H   K + C+ ++ +HLYTLIL+ + TYEV ID +KV SG  EDDWDFL PKKI DP A+KP  W +  ++ D +DKKPEDW+  + IPDP AKKP+DW++ MDG WE P I N +Y G+WKP+ IDNPNY+G W+HPEIDNP Y+PD T+     I  +G DLWQVKSG+IFDN L+T++ E+A++ G  TW +  D E+  +
Sbjct:   14 FSTDGWTKRWVQSKHQ-SDYGQFQLASGKFYQDKERDKGLQTTEDAKFYALSTRF-KPFSNENETLVVQFSVKHEQGIDCGGGYVKLFPAALNQEDMHSESQYYIMFGPDICGFGNNRLQVILSHKGKYHENNKTLKCRINKDTHLYTLILRPNATYEVKIDNQKVTSGGLEDDWDFLPPKKIKDPYARKPRKWDERQQIEDPDDKKPEDWEDSEFIPDPDAKKPDDWNEAMDGVWEGPLIPNVKYMGEWKPRIIDNPNYQGEWIHPEIDNPKYRPDPTIGHYHNISVLGLDLWQVKSGSIFDNFLLTNDEEFAEEVGNMTWGLRKDVEQQWR 344

[Close]

BLAST of calreticulin-1 vs. Ensembl Mouse
Match: Calr3 (calreticulin 3 [Source:MGI Symbol;Acc:MGI:1920566])

HSP 1 Score: 252.677 bits (644), Expect = 2.208e-79
Identity = 155/359 (43.18%), Postives = 203/359 (56.55%), Query Frame = 3

Query:   99 LVILFSAIVNADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDW--KPKEIDNPNYKG----PWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAM 1154
            L+     +  A  T+Y +EEF   +  + +WV+ST   S  G F  ++GKFY   +KDKG+QT+Q+++FY IS    KPFSNK +TLV+Q+ VKHEQ +DCGGGYIK+   DLDQK  +G++ Y IMFGPDICG   KKVHVI  +  + H  KK I CK D F+HLYTLIL+ D +YEV +D + +ESG+ E DW+    +K  +  +    DW            K +DW+K     D  A KP DW              N E  GDW  KP   D    +G     W+H ++    Y     L     IG +G +LWQV+SGTIFDN LITD+ EYA+ FG  TW  T   EK M
Sbjct:    7 LLWAICVLRVALATVYFQEEFLDGERWRNRWVQST-NDSQFGHFRVSSGKFYGHKEKDKGLQTTQNSRFYAISASF-KPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPSDLDQKKMNGKSQYYIMFGPDICGFDIKKVHVILYFKNQYHENKKPIRCKVDGFTHLYTLILRPDLSYEVKVDGQSIESGSIEYDWNLTSLRK-TEKTSLDSRDW------DQVEGSKVQDWEKH--FLDAGASKPSDW--------------NSELDGDWLQKPPYEDGLKAEGIDKDVWLHQKMRPAGYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYAEKFGKATWGETKGPEKEM 340

[Close]

BLAST of calreticulin-1 vs. Ensembl Mouse
Match: Calr4 (calreticulin 4 [Source:MGI Symbol;Acc:MGI:2140435])

HSP 1 Score: 244.202 bits (622), Expect = 6.989e-77
Identity = 127/237 (53.59%), Postives = 168/237 (70.89%), Query Frame = 3

Query:  447 FHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMK 1157
             H E+ Y IMFGPDICG G  ++ VI ++ GK H   K + C+ ++ +HLYTLIL+ + TYEV ID +KV SG  EDDWDFL PKKI DP A+KP  W +  ++ D +DKKPEDW+  + IPDP AKKP+DW++ MDG WE P I N +Y G+WKP+ IDNPNY+G W+HPEIDNP Y+PD T+     I  +G DLWQVKSG+IFDN L+T++ E+A++ G  TW +  D E+  +
Sbjct:    1 MHSESQYYIMFGPDICGFGNNRLQVILSHKGKYHENNKTLKCRINKDTHLYTLILRPNATYEVKIDNQKVTSGGLEDDWDFLPPKKIKDPYARKPRKWDERQQIEDPDDKKPEDWEDSEFIPDPDAKKPDDWNEAMDGVWEGPLIPNVKYMGEWKPRIIDNPNYQGEWIHPEIDNPKYRPDPTIGHYHNISVLGLDLWQVKSGSIFDNFLLTNDEEFAEEVGNMTWGLRKDVEQQWR 237

[Close]

Query:  447 FHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMK 1157
             H E+ Y IMFGPDICG G  ++ VI ++ GK H   K + C+ ++ +HLYTLIL+ + TYEV ID +KV SG  EDDWDFL PKKI DP A+KP  W +  ++ D +DKKPEDW+  + IPDP AKKP+DW++ MDG WE P I N +Y G+WKP+ IDNPNY+G W+HPEIDNP Y+PD T+     I  +G DLWQVKSG+IFDN L+T++ E+A++ G  TW +  D E+  +
Sbjct:    1 MHSESQYYIMFGPDICGFGNNRLQVILSHKGKYHENNKTLKCRINKDTHLYTLILRPNATYEVKIDNQKVTSGGLEDDWDFLPPKKIKDPYARKPRKWDERQQIEDPDDKKPEDWEDSEFIPDPDAKKPDDWNEAMDGVWEGPLIPNVKYMGEWKPRIIDNPNYQGEWIHPEIDNPKYRPDPTIGHYHNISVLGLDLWQVKSGSIFDNFLLTNDEEFAEEVGNMTWGLRKDVEQQWR 237

[Close]

BLAST of calreticulin-1 vs. UniProt/SwissProt
Match: sp|P14211|CALR_MOUSE (Calreticulin OS=Mus musculus OX=10090 GN=Calr PE=1 SV=1)

HSP 1 Score: 438.728 bits (1127), Expect = 1.189e-150
Identity = 230/347 (66.28%), Postives = 272/347 (78.39%), Query Frame = 3

Query:  132 DPTIYLKEEFSTADS-LKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            DP IY KE+F   D+   +WVES +K SD GKF+ ++GKFY D++KDKG+QTSQDA+FY +S K E PFSNK +TLVVQF VKHEQ IDCGGGY+KL    LDQK+ HG++ Y IMFGPDICG GTKKVHVIFNY GKN LI KDI CKDDEF+HLYTLI++ DNTYEV ID  +VESG+ EDDWDFL PKKI DP+A KP DW +  K+ D  D KPEDWDKP+ IPDP AKKPEDWD+EMDGEWE P I NPEY+G+WKP++IDNP+YKG W+HPEIDNP+Y PD  +Y       +G DLWQVKSGTIFDN LIT++  YA++FG +TW VT   EK MK+K D
Sbjct:   18 DPAIYFKEQFLDGDAWTNRWVESKHK-SDFGKFVLSSGKFYGDLEKDKGLQTSQDARFYALSAKFE-PFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPSGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362

[Close]

BLAST of calreticulin-1 vs. UniProt/SwissProt
Match: sp|P18418|CALR_RAT (Calreticulin OS=Rattus norvegicus OX=10116 GN=Calr PE=1 SV=1)

HSP 1 Score: 436.417 bits (1121), Expect = 1.146e-149
Identity = 229/347 (65.99%), Postives = 271/347 (78.10%), Query Frame = 3

Query:  132 DPTIYLKEEFSTADS-LKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            DP IY KE+F   D+   +WVES +K SD GKF+ ++GKFY D +KDKG+QTSQDA+FY +S + E PFSNK +TLVVQF VKHEQ IDCGGGY+KL    LDQK+ HG++ Y IMFGPDICG GTKKVHVIFNY GKN LI KDI CKDDEF+HLYTLI++ DNTYEV ID  +VESG+ EDDWDFL PKKI DP+A KP DW +  K+ D  D KPEDWDKP+ IPDP AKKPEDWD+EMDGEWE P I NPEY+G+WKP++IDNP+YKG W+HPEIDNP+Y PD  +Y       +G DLWQVKSGTIFDN LIT++  YA++FG +TW VT   EK MK+K D
Sbjct:   18 DPAIYFKEQFLDGDAWTNRWVESKHK-SDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFE-PFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPGGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362

[Close]

BLAST of calreticulin-1 vs. UniProt/SwissProt
Match: sp|P29413|CALR_DROME (Calreticulin OS=Drosophila melanogaster OX=7227 GN=Calr PE=1 SV=2)

HSP 1 Score: 435.261 bits (1118), Expect = 1.725e-149
Identity = 232/363 (63.91%), Postives = 270/363 (74.38%), Query Frame = 3

Query:   84 MMYYILVILFSAIVN-ADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            MM+   VI+  A V      +YLKE F   +    W+ S + G + GKF+ T G FY+D + DKGIQTSQDA+FY  S K +  FSN+D+ LVVQF VKHEQ IDCGGGY+KL    LDQ + HGE+PYEIMFGPDICG GTKKVHVIF+Y GKNHLI KDI CKDD ++H YTLI++ DNTYEVLID EKVESGN EDDWDFL PKKI DP A KP DW D   +PD +DKKPEDWDKP+ IPDP A KPEDWDDEMDGEWE P IDNPE++G+W+PK++DNPNYKG W HPEI NP+Y PD+ LYLR EI  +GFDLWQVKSGTIFDN+LITD+ E A     +  + T  GEK MK   D
Sbjct:    1 MMWCKTVIVLLATVGFISAEVYLKENFDNENWEDTWIYSKHPGKEFGKFVLTPGTFYNDAEADKGIQTSQDARFYAASRKFDG-FSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCSLDQTDMHGESPYEIMFGPDICGPGTKKVHVIFSYKGKNHLISKDIRCKDDVYTHFYTLIVRPDNTYEVLIDNEKVESGNLEDDWDFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDWDKPEHIPDPDATKPEDWDDEMDGEWEPPMIDNPEFKGEWQPKQLDNPNYKGAWEHPEIANPEYVPDDKLYLRKEICTLGFDLWQVKSGTIFDNVLITDDVELAAKAAAEV-KNTQAGEKKMKEAQD 361

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BLAST of calreticulin-1 vs. UniProt/SwissProt
Match: sp|P15253|CALR_RABIT (Calreticulin OS=Oryctolagus cuniculus OX=9986 GN=CALR PE=1 SV=1)

HSP 1 Score: 434.491 bits (1116), Expect = 6.708e-149
Identity = 226/348 (64.94%), Postives = 271/348 (77.87%), Query Frame = 3

Query:  129 ADPTIYLKEEFSTADS-LKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            A+P +Y KE+F   D   ++W+ES +K SD GKF+ ++GKFY D +KDKG+QTSQDA+FY +S + E PFSNK + LVVQF VKHEQ IDCGGGY+KL    LDQK+ HG++ Y IMFGPDICG GTKKVHVIFNY GKN LI KDI CKDDEF+HLYTLI++ DNTYEV ID  +VESG+ EDDWDFL PKKI DP+A KP DW +  K+ D  D KPEDWDKP+ IPDP AKKPEDWD+EMDGEWE P I NPEY+G+WKP++IDNP+YKG W+HPEIDNP+Y PD  +Y       +G DLWQVKSGTIFDN LIT++  YA++FG +TW VT   EK MK+K D
Sbjct:   17 AEPVVYFKEQFLDGDGWTERWIESKHK-SDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFE-PFSNKGQPLVVQFTVKHEQNIDCGGGYVKLFPAGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKTAEKQMKDKQD 362

[Close]

BLAST of calreticulin-1 vs. UniProt/SwissProt
Match: sp|P52193|CALR_BOVIN (Calreticulin OS=Bos taurus OX=9913 GN=CALR PE=1 SV=2)

HSP 1 Score: 434.106 bits (1115), Expect = 7.718e-149
Identity = 227/348 (65.23%), Postives = 271/348 (77.87%), Query Frame = 3

Query:  129 ADPTIYLKEEFSTADS-LKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            ADPT+Y KE+F   D   ++W+ES +K  D GKF+ ++GKFY D +KDKG+QTSQDA+FY +S + E PFSNK +TLVVQF VKHEQ IDCGGGY+KL    LDQ + HG++ Y IMFGPDICG GTKKVHVIFNY GKN LI KDI CKDDEF+HLYTLI++ +NTYEV ID  +VESG+ EDDWDFL PKKI DP+A KP DW D  K+ D  D KPEDWDKP+ IPDP AKKPEDWD+EMDGEWE P I NPEY+G+WKP++IDNP YKG W+HPEIDNP+Y PD+ +Y       +G DLWQVKSGTIFDN LIT++  YA++FG +TW VT   EK MK+K D
Sbjct:   17 ADPTVYFKEQFLDGDGWTERWIESKHK-PDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFE-PFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPAGLDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPNNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDDRAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPEYKGIWIHPEIDNPEYSPDSNIYAYENFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362

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BLAST of calreticulin-1 vs. TrEMBL
Match: I1ZIA6 (Calreticulin OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 747.658 bits (1929), Expect = 0.000e+0
Identity = 407/409 (99.51%), Postives = 408/409 (99.76%), Query Frame = 3

Query:   84 MMYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLDXXXXXXXXXXXXXXXXXXXXXPKVEEQDKAPESEEAESKDKVDHTEL 1310
            MMYYILVILF AIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPEDWDDEMDGEWEAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLDEE+RKRTEEEDKKKEATKQAEPKVEEQDKAPESEEAESKDKVDHTEL
Sbjct:    1 MMYYILVILFCAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPEDWDDEMDGEWEAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLDEEERKRTEEEDKKKEATKQAEPKVEEQDKAPESEEAESKDKVDHTEL 409

[Close]

BLAST of calreticulin-1 vs. TrEMBL
Match: V9XRS2 (Calreticulin OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 521.931 bits (1343), Expect = 0.000e+0
Identity = 266/362 (73.48%), Postives = 306/362 (84.53%), Query Frame = 3

Query:   84 MMYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            M  +I+ IL S  + A+PTIYL EEF T     +WVEST+KG+DQGKF +TAGKFY+D +KDKGIQTSQDAKFYGIS K +K FSN+ + LV+QFQVKHEQTIDCGGGY+KL+G + +Q  FHGETPY IMFGPDICG+ TKKVHVIFNY G+N LIKKDI CKDDEF+H+YTLI+  DNTYEVLID EKVESG+ EDDWDFL PKKI DPNA+KP DW D  K+ D  DKKPE+WDKPKTIPDPKAKKPEDWDDEMDGEWEAP+IDNPEY+G+WKPK+IDNP YKGPWVHPEI NPDYKPD  LY+  +IG +GFDLWQVKSGTIFDNIL+TD+P YAK +  +TW+VTADGEK MK+K D
Sbjct:    1 MKIFIMSILVSLAL-AEPTIYLNEEFLTESYKTQWVESTFKGADQGKFTWTAGKFYNDAEKDKGIQTSQDAKFYGISKKFDKAFSNEGKKLVIQFQVKHEQTIDCGGGYVKLVGSNFEQDKFHGETPYHIMFGPDICGLSTKKVHVIFNYKGQNLLIKKDIKCKDDEFTHVYTLIVNPDNTYEVLIDNEKVESGSLEDDWDFLAPKKIKDPNAKKPEDWEDNEKIDDITDKKPEEWDKPKTIPDPKAKKPEDWDDEMDGEWEAPQIDNPEYKGEWKPKQIDNPKYKGPWVHPEIPNPDYKPDTNLYVYKDIGAIGFDLWQVKSGTIFDNILLTDDPAYAKKYAEQTWKVTADGEKKMKDKQD 361

[Close]

BLAST of calreticulin-1 vs. TrEMBL
Match: A0A267FN87 (Calreticulin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig004264g3 PE=3 SV=1)

HSP 1 Score: 470.315 bits (1209), Expect = 1.098e-160
Identity = 243/343 (70.85%), Postives = 280/343 (81.63%), Query Frame = 3

Query:  141 IYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            +Y KEEF       +WVESTYKG+DQGK+ +TAGKFY+D +KDKGI+TSQDAKFYGIS K   PFSN  +TLV+QFQVKHEQ IDCGGGY+K++G D+DQKNFHG+TPY+IMFGPDICG GTKKVHVIFNY GKN L KK+I CKDDE SHLYTLI+K DNTYEVLID E+ E G  E DWDFL PKKI DP A+KP DW +  K+ D NDKKPEDWDKPKTIPDPKAKKP+DWDDEMDGEWE P IDNP+Y+GDWKPK+IDNP YKG W+HPEIDNPDY PD  LY   +IG +GFDLWQVKSG+IFDN+ + D+P  AK F  +T++ T +GEK MK K D
Sbjct:   19 VYFKEEFLDESWKDRWVESTYKGNDQGKWEWTAGKFYNDAEKDKGIKTSQDAKFYGISAKFNSPFSNAGKTLVIQFQVKHEQNIDCGGGYVKVLGSDVDQKNFHGDTPYKIMFGPDICGPGTKKVHVIFNYKGKNLLTKKEIRCKDDELSHLYTLIVKPDNTYEVLIDNERAEGGELEADWDFLPPKKIKDPAAKKPDDWDEREKIDDPNDKKPEDWDKPKTIPDPKAKKPDDWDDEMDGEWEPPMIDNPDYKGDWKPKQIDNPAYKGKWIHPEIDNPDYSPDPELYKYTDIGAIGFDLWQVKSGSIFDNVFVGDDPAEAKAFADETFKKTVEGEKKMKEKQD 361

[Close]

BLAST of calreticulin-1 vs. TrEMBL
Match: A1YB06 (Calreticulin OS=Eisenia andrei OX=168636 PE=2 SV=1)

HSP 1 Score: 468.389 bits (1204), Expect = 1.004e-159
Identity = 238/361 (65.93%), Postives = 287/361 (79.50%), Query Frame = 3

Query:   84 MMYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKL 1166
            ++  + V   +AI  A+PT Y +E+F  A    +WVEST+KG++QGKF +TAGKFY+D +KDKG+QT+QDA+FYGIS K +KPF+N+ +TL++QF VKHEQ IDCGGGYIKL   DLDQKN HGE+PY IMFGPDICG  TKKVHVIFNY GKN LIKK+I CKDD  SHLYTLI++ DNTYEV ID +K ESG  +DDWDFL PKKI DP A+KP DW D  K+ D  D KPEDWDK + IPDP+AKKPEDWDDEMDGEWE P IDNPEY+G+WKPK+I NP YKG WVHPEIDNP+Y  D++LY   +IG +GFDLWQVKSGTIFDN+LITD+ ++A++ G +TW    DGEK MK+K 
Sbjct:    3 VIRAVFVACLAAIALAEPTTYFREDFD-AGWKSRWVESTHKGAEQGKFAWTAGKFYNDAEKDKGLQTTQDARFYGISAKFDKPFTNEGKTLIIQFTVKHEQEIDCGGGYIKLFSSDLDQKNMHGESPYYIMFGPDICGYSTKKVHVIFNYKGKNLLIKKEIRCKDDTLSHLYTLIVRPDNTYEVKIDNKKEESGKLDDDWDFLAPKKIKDPEAKKPEDWDDREKLDDPEDTKPEDWDKAEHIPDPEAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQITNPAYKGAWVHPEIDNPEYAADDSLYRYSDIGAIGFDLWQVKSGTIFDNMLITDDEKFAEEVGEETWGKAKDGEKKMKDKF 362

[Close]

BLAST of calreticulin-1 vs. TrEMBL
Match: A0A1I8I182 (Calreticulin OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 463.766 bits (1192), Expect = 1.411e-158
Identity = 240/361 (66.48%), Postives = 286/361 (79.22%), Query Frame = 3

Query:   87 MYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            M     +L + +  A   +Y KEEF       +WVESTYKG+DQGK+ ++AGKFY+D  KD+GI+T+QDAKFY IS K +KPFSN+ + LV+QFQVKHEQ IDCGGGY+KL+G D+DQKNFHG++PY+IMFGPDICG GTKKVHVIFNY GKN L KK+I CKDDE SHLYTLI+K DNTYEVLID E+ E G  E DWDFL PKKI DP A+KP DW +  K+ D NDKKPEDWDKPKTIPDPKAKKP+DWDDEMDGEWE P IDNP+Y+G+WKPK+IDNP YKG W+HPEIDNPDY PD  LY   +IG +GFDLWQVKSG+IFDN+ + D+P  A+ F  +T++ T +GEK MK K D
Sbjct:    1 MIKWFFVLAALLPFAFCEVYFKEEFLDESWRDRWVESTYKGADQGKWDWSAGKFYNDAQKDRGIKTTQDAKFYDISAKFDKPFSNQGKPLVIQFQVKHEQNIDCGGGYVKLLGSDIDQKNFHGDSPYKIMFGPDICGPGTKKVHVIFNYKGKNLLTKKEIRCKDDELSHLYTLIVKPDNTYEVLIDNERAEGGELEADWDFLPPKKIKDPAAKKPDDWDEREKIDDPNDKKPEDWDKPKTIPDPKAKKPDDWDDEMDGEWEPPMIDNPDYKGEWKPKQIDNPAYKGKWIHPEIDNPDYSPDPELYKYTDIGAIGFDLWQVKSGSIFDNVFVGDDPAEARTFADETFKKTVEGEKKMKEKQD 361

[Close]

BLAST of calreticulin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000019127.2 (calreticulin-like [Source:NCBI gene;Acc:103024869])

HSP 1 Score: 442.195 bits (1136), Expect = 6.318e-153
Identity = 233/359 (64.90%), Postives = 280/359 (77.99%), Query Frame = 3

Query:   93 YILVILFSAIVN--ADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKN 1160
            ++L +  SA  +  A+P +YL+E+F   D+ K +WVES +K SD GKF+ TAGKFY D +KDKG+QTSQDA FY IS +  K FSNKD+TLV+QF VKHEQ+IDCGGGYIKL   DL Q++ HG++ Y IMFGPDICG GTKKVHVIFNY GKNHLI KDI CKDDE +HLYTLI+  DNTYEV ID +KVESG+ EDDWDFL PKKI DPNA+KP DW +  K+ D  D+KPEDW+K + IPDP AKKP+DWDDEMDGEWE P + NPEY+G+WKPK+IDNP YKG WVHPEIDNP+Y  D  +Y    IG +G DLWQVKSGTIFDN LIT++P+ A++ G +TW  T D EK MK+
Sbjct:    5 FLLALCVSAAFSTAAEPAVYLREQFEDGDAWKTRWVESEHK-SDYGKFVLTAGKFYGDAEKDKGLQTSQDAHFYSISSRF-KDFSNKDQTLVLQFTVKHEQSIDCGGGYIKLFPSDLKQEDMHGDSIYNIMFGPDICGPGTKKVHVIFNYKGKNHLINKDIRCKDDEHTHLYTLIVNPDNTYEVKIDNKKVESGSLEDDWDFLPPKKIKDPNAKKPEDWDEREKIDDPEDQKPEDWEKAENIPDPDAKKPDDWDDEMDGEWEPPMVSNPEYKGEWKPKQIDNPGYKGKWVHPEIDNPEYTADPEIYAYSSIGVIGLDLWQVKSGTIFDNFLITNDPKLAEEIGNETWGATKDAEKKMKD 361

[Close]

BLAST of calreticulin-1 vs. Ensembl Cavefish
Match: calr3b (calreticulin-like [Source:NCBI gene;Acc:103040817])

HSP 1 Score: 422.55 bits (1085), Expect = 3.637e-145
Identity = 224/343 (65.31%), Postives = 263/343 (76.68%), Query Frame = 3

Query:  129 ADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAM 1154
             D T+Y KE+F      K +WV S +K SD G+F  T+G FY D++KDKG+QTSQDA+FY  S + E PFSN+ ++LVVQF VKHEQ IDCGGGY+K+   DLDQ N HG++ Y IMFGPDICG  TKKVHVIFNY GKNHLIKK+I CKDDE +HLYTLIL  D TYEV ID EKVESG+ E+DWDFL  KKI DP A+KP DW D  K+ DE D KPEDWDKP+ IPDP AKKPEDWD++MDGEWE P I NPEY+G+WKPK+IDNPNYKG WVHPEIDNP+Y PD  +Y   +IG +G DLWQVK+GTIFDN LITD+ + A +F  +TW VT   EK M
Sbjct:   19 VDATVYFKEQFLDGGEWKSRWVNSEHK-SDYGQFKLTSGNFYGDVEKDKGLQTSQDARFYAASARFE-PFSNEGKSLVVQFSVKHEQKIDCGGGYVKIFPSDLDQTNMHGDSQYYIMFGPDICGYSTKKVHVIFNYKGKNHLIKKEIKCKDDELTHLYTLILNPDQTYEVKIDNEKVESGSLEEDWDFLPAKKIKDPEAKKPEDWDDRAKIDDETDTKPEDWDKPENIPDPDAKKPEDWDEDMDGEWEPPMIPNPEYKGEWKPKQIDNPNYKGAWVHPEIDNPEYSPDAEIYKFEKIGVLGLDLWQVKAGTIFDNFLITDDVQTADEFAKETWGVTKGPEKKM 359

[Close]

BLAST of calreticulin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000022283.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:25050572:25055355:1 gene:ENSAMXG00000021635.2 transcript:ENSAMXT00000022283.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 386.341 bits (991), Expect = 1.780e-131
Identity = 202/311 (64.95%), Postives = 240/311 (77.17%), Query Frame = 3

Query:  237 AGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            A  F+ +   D G+QTSQDA+FY +S + E PFSN+ + LV+QF VKHEQ IDCGGGY+K+   DLDQ N HG++ Y IMFGPDICG  TKKVHVIFNY G+NHLIKKDI CKDDE +HLYTLIL  D TYEV I+ EKVESG+ E+DWDFL PKKI DP A+KP DW D  K+ D  D KPEDWDKP+ IPDP AKKP+DWD++MDGEWE P I NPEY+G+WKPK+IDNPNYKG WVHPEIDNP+Y  D+++Y    IG +G DLWQVKSGTIFDN  I+D+ + A++FG +TW  T   EK MK K D
Sbjct:   19 ATVFFKEQFLDGGLQTSQDARFYALSSRFE-PFSNEGKPLVIQFTVKHEQKIDCGGGYVKIFPTDLDQANMHGDSQYYIMFGPDICGYSTKKVHVIFNYKGQNHLIKKDIRCKDDEHTHLYTLILHPDQTYEVKINNEKVESGSLEEDWDFLPPKKIKDPEAKKPEDWDDRAKIDDPEDTKPEDWDKPENIPDPDAKKPDDWDEDMDGEWEPPMIPNPEYKGEWKPKQIDNPNYKGTWVHPEIDNPEYTADDSIYKYDNIGVLGLDLWQVKSGTIFDNFFISDDVKEAEEFGKETWGATKGPEKKMKEKQD 328

[Close]

BLAST of calreticulin-1 vs. Ensembl Cavefish
Match: clgn (calnexin [Source:NCBI gene;Acc:103035256])

HSP 1 Score: 189.119 bits (479), Expect = 3.397e-53
Identity = 133/340 (39.12%), Postives = 176/340 (51.76%), Query Frame = 3

Query:  267 DKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMG--KDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNG-------KNHLIKKDIPCK---DDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDW--DFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDK---------------------PKTIPDPKAKKPXXXXXXXXXXXXAPK-------------------IDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTW 1124
            D G+     AK + IS  L KP+  KDR LVVQ++V  +  IDCGG YIKL+    DLD + FH  TPY IMFGPD CG    K+H IF +         + H  + D   +    D+ +HL+TL+L  DN+YE+ ID      GN   D       PK+I+DP   KP DW +  K+PD    KP+DWD+                     P+ +PDP A KP+DWD+EMDGEWEAP+                   I+NP+Y+G WK   IDNPNY+G W   +I NPDY  D   +    +  VG +LW + S   FDN +IT + E A  +   +W
Sbjct:  119 DLGLVLKSRAKHHAISSPLSKPYIFKDRPLVVQYEVNFQDGIDCGGAYIKLLSDSPDLDLEQFHDRTPYSIMFGPDKCG-EDYKLHFIFRHKNPLNEDFEEKHAKRADADLRKVYSDKKTHLFTLVLNPDNSYEIFIDQSSASKGNLLTDVIPPVNPPKEIDDPKDTKPEDWDERAKIPDPEAVKPDDWDEEAPAMIPDPDALKPDGWLDEEPEFVPDPTATKPDDWDEEMDGEWEAPQVPNPACQTAPGCGEWKSPTINNPKYKGKWKAPLIDNPNYQGVWSPRKILNPDYFEDLEPFKMTAVRAVGLELWSMTSDIYFDNFIITADKEVADRWAADSW 457

[Close]

BLAST of calreticulin-1 vs. Ensembl Cavefish
Match: clgn (calnexin [Source:NCBI gene;Acc:103035256])

HSP 1 Score: 189.889 bits (481), Expect = 3.951e-53
Identity = 133/340 (39.12%), Postives = 176/340 (51.76%), Query Frame = 3

Query:  267 DKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMG--KDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNG-------KNHLIKKDIPCK---DDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDW--DFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDK---------------------PKTIPDPKAKKPXXXXXXXXXXXXAPK-------------------IDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTW 1124
            D G+     AK + IS  L KP+  KDR LVVQ++V  +  IDCGG YIKL+    DLD + FH  TPY IMFGPD CG    K+H IF +         + H  + D   +    D+ +HL+TL+L  DN+YE+ ID      GN   D       PK+I+DP   KP DW +  K+PD    KP+DWD+                     P+ +PDP A KP+DWD+EMDGEWEAP+                   I+NP+Y+G WK   IDNPNY+G W   +I NPDY  D   +    +  VG +LW + S   FDN +IT + E A  +   +W
Sbjct:  119 DLGLVLKSRAKHHAISSPLSKPYIFKDRPLVVQYEVNFQDGIDCGGAYIKLLSDSPDLDLEQFHDRTPYSIMFGPDKCG-EDYKLHFIFRHKNPLNEDFEEKHAKRADADLRKVYSDKKTHLFTLVLNPDNSYEIFIDQSSASKGNLLTDVIPPVNPPKEIDDPKDTKPEDWDERAKIPDPEAVKPDDWDEEAPAMIPDPDALKPDGWLDEEPEFVPDPTATKPDDWDEEMDGEWEAPQVPNPACQTAPGCGEWKSPTINNPKYKGKWKAPLIDNPNYQGVWSPRKILNPDYFEDLEPFKMTAVRAVGLELWSMTSDIYFDNFIITADKEVADRWAADSW 457

[Close]

BLAST of calreticulin-1 vs. Ensembl Sea Lamprey
Match: calr (calreticulin [Source:ZFIN;Acc:ZDB-GENE-030131-4042])

HSP 1 Score: 422.165 bits (1084), Expect = 3.069e-146
Identity = 224/346 (64.74%), Postives = 271/346 (78.32%), Query Frame = 3

Query:  132 DPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPE---DWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMK 1157
            +P +Y KE F   D+ + +WV S +K SD GKF+ +AGKFY D +KDKG+QTSQDA+FY +S   +  FSNKD+TLV+QF VKHEQ IDCGGGYIKL  KD++Q+  HG++ Y IMFGPDICG GTKKVHVIFNY GKNHLI KDI CKDDE++HLYTLI++ D TYEV ID +KVESG+ E+DWD L  KKI DP A KP DW D+ K+ D  D KPE   DW+KP+ IPDP AKKPEDWDDEMDGEWE P ++NPEY+G+WKP++IDNP YKG WVHPEIDNP+Y PD+ +YL   IG +G DLWQVKSGTIFD+ LITD+ +YA+  G +TW VT +GEK MK
Sbjct:   19 EPAVYFKELFDDGDAWQDRWVVSKHK-SDYGKFVLSAGKFYGDAEKDKGLQTSQDARFYALSAGFDS-FSNKDKTLVIQFTVKHEQNIDCGGGYIKLFPKDMNQEEMHGDSQYFIMFGPDICGPGTKKVHVIFNYKGKNHLINKDIRCKDDEYTHLYTLIVRPDQTYEVKIDNKKVESGSLEEDWDILPAKKIKDPEAHKPEDWEDQSKIDDPTDVKPEPTKDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPMVENPEYKGEWKPRQIDNPKYKGVWVHPEIDNPEYAPDSNIYLSENIGVIGLDLWQVKSGTIFDSFLITDDEKYAETIGEETWGVTKEGEKKMK 362

[Close]

BLAST of calreticulin-1 vs. Ensembl Sea Lamprey
Match: calr3b (calreticulin 3b [Source:ZFIN;Acc:ZDB-GENE-030131-9907])

HSP 1 Score: 395.971 bits (1016), Expect = 2.218e-135
Identity = 211/365 (57.81%), Postives = 269/365 (73.70%), Query Frame = 3

Query:   84 MMYYILVILFSAIVNADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMF--GPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDEND-KKP---EDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMK 1157
            MM  +L +  +A   A   ++ +E FS  D  + +WVES +K SD GK   +AG FY D ++DKG+QT+QD +FY IS     PFSNK RTLV+QF VKHEQ IDCGGGY+KL   +LDQ++ HG++ Y +MF  GPDICG GTKKVHVI NY GKNHLI KDI C+DDEF+HLYTL+L+ D TYEV ID E+VESG+ EDDWD L P+++ DP A +P DW + P + D +D KKP   +DWD+P+ IPDP AKKP+DWDDEMDGEWE P ++NP+++ +WKPK+I NP+YKG WVHP+IDNPD+  D  +Y    IG +G DLWQVKSGTIFDN LITD+ +YA++   KTW +T D E+ MK
Sbjct:    2 MMKAVLTLWLTASW-AMAEVFFEERFSDGDGWQPRWVESQHK-SDYGKMRLSAGAFYGDAERDKGLQTTQDVRFYAISAAF-PPFSNKGRTLVLQFSVKHEQDIDCGGGYVKLFPAELDQQDMHGDSRYYLMFAEGPDICGPGTKKVHVIINYKGKNHLINKDIRCRDDEFTHLYTLVLRPDQTYEVKIDGERVESGSLEDDWDVLPPRRVEDPAAVRPDDWDERPSIDDPHDTKKPDRGQDWDQPEHIPDPDAKKPDDWDDEMDGEWEPPMVENPDFKSEWKPKQISNPDYKGTWVHPKIDNPDFASDPNIYYFDNIGVLGLDLWQVKSGTIFDNFLITDDEQYAEEVAKKTWGLTKDAERKMK 363

[Close]

BLAST of calreticulin-1 vs. Ensembl Sea Lamprey
Match: si:ch211-274f20.2 (si:ch211-274f20.2 [Source:ZFIN;Acc:ZDB-GENE-091204-91])

HSP 1 Score: 181.03 bits (458), Expect = 1.318e-50
Identity = 133/400 (33.25%), Postives = 185/400 (46.25%), Query Frame = 3

Query:  144 YLKEEFSTADSLKKWVESTYKGSDQ--------GKFIYTA---GKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMG--KDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKN------HLIKKDI---PCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGN-FEDDWDFLQP-KKINDPNAQKPADWVDEPKMPDENDKKPEDWDK--PKTIPDPKAKK--------------------------------------PXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKA 1151
            Y  + F +  +L  WV S  K  D         GK++      GK  DD    KG+     AK + I+  L +PF   D+ L+VQ++V  +  I+CGG Y+KL+    DLD   F+ +TPY IMFGPD CG   K   ++ + N K       H  K D+   P   D+  HLY+L+L  DN YE+LID   V SG+  ED    + P ++I DP+  KP DW +  K+PD +  KPEDWD+  P  I DP A K                                      P        G W+AP + NP Y+G WKP  IDNPNY+G W   +I NPD+  D   +       +G +LW + S  +FDN ++  E   A  +   +W +      A
Sbjct:  115 YFVDSFDSG-TLDNWVISKAKKEDTDEDIAKYDGKWLVEEQLDGKLPDD----KGLVLKTRAKHHAIAGALTRPFHFIDKPLIVQYEVNFQNGIECGGAYVKLLSGNADLDLTKFYDKTPYTIMFGPDKCGEDYKLHFIMRHRNPKTGTYEEKHAKKSDVDLKPYYTDKKPHLYSLVLSPDNRYEILIDQTVVGSGSLLEDMTPPVNPAREIEDPDDSKPEDWDERAKIPDPDAIKPEDWDEDAPAQISDPDAVKPEGWLDDEPEYTADPEAVKPEDWDEEMDGEWEAPQVPNPTCEAAPGCGVWKAPMVSNPAYKGKWKPSNIDNPNYQGVWKPRKIANPDFFEDLHPFRLTAFNAIGLELWSMTSDILFDNFIVCSERAVADQWAADSWGLKRQAAAA 509

[Close]

BLAST of calreticulin-1 vs. Ensembl Yeast
Match: CNE1 (Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast [Source:SGD;Acc:S000000054])

HSP 1 Score: 108.997 bits (271), Expect = 4.578e-26
Identity = 116/405 (28.64%), Postives = 170/405 (41.98%), Query Frame = 3

Query:  111 FSAIVNADPTIYLKEEFSTADSLKKWVESTYKGS---DQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDR-TLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETP----YEIMFGPDICGIGTKKVHVIFNYNGK-NHLIK----KDIPCK---DDEFSHLYTLIL-KSDNTYEVLID---------LEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKK-------------------PEDWDK--PKTIPDPKAKKPXXXXXXXXXXXXAPKIDNP-------------------EYRGDWKPKEIDNPNYKGPWVHPEIDNPD-YKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTW 1124
            F A  N   T +L +E+ T++++       Y       QG+   +A         DKGI          I + LE P +  +  TLVVQ+++K + ++ CGG +IKLM   ++ +      P     E++FGPD C      V    N   K  H  K    +++P     D   SHLYTLI+ +S  ++++LID         +E  +  NFE       P  I D +  KP DW D  ++PD    K                   P +W+   P+ I DP A+KP  W +   GEW  P I NP                   +Y+G  +  EI NPNY G W  PEI+NP  Y+  + L +   I  V  + W      +  NI +      A+  G KTW
Sbjct:   37 FQAYTN---TKHLNQEWITSEAVNNEGSKIYGAQWRLSQGRLQGSAW--------DKGIAVRTGNAAAMIGHLLETPINVSETDTLVVQYEIKLDNSLTCGGAFIKLMSGFMNVEALKHYAPDTEGVELVFGPDYCAPEINGVQFAINKVDKITHESKLRYLQEMPLSKLTDTSQSHLYTLIIDESAQSFQILIDGKTVMVREHIEDKKKVNFEPP--ITPPLMIPDVSVAKPHDWDDRIRIPDPEAVKLSDRDERDPLMIPHPDGTEPPEWNSSIPEYILDPNAQKPSWWKELEHGEWIPPMIKNPLCTAERGCGQQIPGLINNAKYKGPGELNEIINPNYMGEWHPPEIENPLYYEEQHPLRIENVISGVILEFWSGSPNMLISNIYVGKNVTEAQIIGNKTW 428

[Close]

BLAST of calreticulin-1 vs. Ensembl Nematostella
Match: EDO48109 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK57])

HSP 1 Score: 444.506 bits (1142), Expect = 4.457e-155
Identity = 230/329 (69.91%), Postives = 268/329 (81.46%), Query Frame = 3

Query:  183 KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            +WV ST KG+ QGKF +TAGKFY D + DKGIQTS+DAKFYGIS K EKPF+N+ +TLV+QF VKHEQ IDCGGGY K+   D+DQKN HG++PY IMFGPDICG GTKKVHVIFNY GKN L KKDI CKDDE +HLYTLI++ DNTYEV ID EKVESG  E DWDFL PK I DP A+KP DW D+  + D  DKKPEDWDKP+ IPDP AKKPEDWDDE+DGEWE P IDNPEY+G+WKPK+IDNPNYKG WVHPEIDNP+YK D+ LY+  +IG +GFDLWQVKSGTIFDN+L+TD  E+A+ F  +T+  T +GEK MK++ D
Sbjct:    5 RWVSSTSKGAQQGKFKWTAGKFYGDAEADKGIQTSEDAKFYGISAKFEKPFTNEGKTLVIQFSVKHEQNIDCGGGYAKVFPSDVDQKNLHGDSPYLIMFGPDICGPGTKKVHVIFNYKGKNLLTKKDIRCKDDEMTHLYTLIVRPDNTYEVKIDNEKVESGELEKDWDFLPPKTIKDPEAKKPEDWDDKKMIDDPEDKKPEDWDKPQNIPDPDAKKPEDWDDEIDGEWEPPMIDNPEYKGEWKPKQIDNPNYKGEWVHPEIDNPEYKADDKLYMYKDIGAIGFDLWQVKSGTIFDNVLVTDSVEHAEQFAKETFDKTKEGEKKMKDEQD 333

[Close]

BLAST of calreticulin-1 vs. Ensembl Nematostella
Match: EDO49786 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFV3])

HSP 1 Score: 181.03 bits (458), Expect = 7.093e-52
Identity = 132/341 (38.71%), Postives = 186/341 (54.55%), Query Frame = 3

Query:  267 DKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLM--GKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNY-NGKNHLIKKDIPCK---------DDEFSHLYTLILKSDNTYEVLIDLEKVESGNF---------------------EDDWDFLQPKKINDPNAQKPADW-VDEP-KMPDENDKKPEDW--DKPKTIPDPKAKKPXXXXXXXXXXXXAPKI------------------DNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTW 1124
            D G+     A+ + I+  L+K F   D+  +VQ++VK +Q ++CGG Y+KL+  G+    ++F  +TPY IMFGPD CG   +K+H IF + N KN  I++    K         D + +HL+TL+++ DNT+EV ID E V  G+                       +DWD  + +KI DP+A+KP DW  D P K+PD N KKPE W  D+P+ +PDP   KPEDWDDE DGEWEAP+I                  DNPEY+G W    IDNPNYKG W    I NP +  D   +    I  VG +LW + S  +FDN+++T++   A  +   +W
Sbjct:   35 DLGLVLKSRARHHAIAAHLDKKFDFTDKPFIVQYEVKFQQPMECGGAYLKLLSDGQGFKPESFGDKTPYTIMFGPDKCG-EDRKLHFIFRHKNPKNGTIEEKHAKKPTGNYNSVFDGKKTHLFTLVVRPDNTFEVFIDQESVNKGSLLEDMTPPVNPPAEIEDPDDKRPEDWD--EREKIPDPDAEKPDDWDEDAPVKIPDTNAKKPEGWLDDEPEYVPDPNGIKPEDWDDEEDGEWEAPQIANPKCEKVGCGEWKPPMADNPEYKGKWSAPLIDNPNYKGIWKPRLIPNPHFFEDKEPFKMTSIVGVGLELWSMTSDILFDNVIVTNDKAVADKWAQDSW 372

[Close]

BLAST of calreticulin-1 vs. Ensembl Medaka
Match: ENSORLT00000003653.2 (calreticulin [Source:NCBI gene;Acc:101160304])

HSP 1 Score: 425.631 bits (1093), Expect = 1.853e-146
Identity = 217/360 (60.28%), Postives = 274/360 (76.11%), Query Frame = 3

Query:   84 MMYYILVILFSAIVNADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKN 1160
            M +   ++   A V  + T+Y +EEF+  D  K +W+ES +K SD G++  ++GKFY D + DKG+QTSQDA+FY +S +   PFSN+ +TLV+QF VKHEQ IDCGGGY+K+   DLDQ + HG++ Y +MFGPDICG  TKKVHVIFNY G+NHLIKKDI CKDDE +HLYTLIL  D TYEV ID EKVESG+ EDDWD L PKKI DP+A+KP+DW D   + D +D KPEDWD+P+TIPDP AKKP+DWD++MDGEWE P I NPE++G+WKPK++ NPNYKG WVHPE+DNP+Y PD  +YL   IG +G DLWQVKSGTIFDN LITD+ + A++   +TW VT   EK M++
Sbjct:    1 MKFCSALLALFAGVAVEATVYFREEFTDGDGWKSRWLESKHK-SDYGQWKLSSGKFYGDAEADKGVQTSQDARFYALSARF-PPFSNEGKTLVIQFTVKHEQKIDCGGGYVKVFPSDLDQSDMHGDSKYYVMFGPDICGYSTKKVHVIFNYKGQNHLIKKDIKCKDDELTHLYTLILNPDQTYEVRIDNEKVESGSLEDDWDMLPPKKIKDPDAKKPSDWDDRATIDDPSDTKPEDWDQPETIPDPDAKKPDDWDEDMDGEWEPPMITNPEFKGEWKPKQMSNPNYKGAWVHPEVDNPEYAPDANMYLFDNIGVLGLDLWQVKSGTIFDNFLITDDIKEAEEVAKETWEVTKGPEKKMRD 358

[Close]

BLAST of calreticulin-1 vs. Ensembl Medaka
Match: calr3b (calreticulin [Source:NCBI gene;Acc:101169735])

HSP 1 Score: 423.705 bits (1088), Expect = 1.042e-145
Identity = 222/363 (61.16%), Postives = 270/363 (74.38%), Query Frame = 3

Query:   84 MMYYILVILFSAIVNADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            M    L +   A+      IY +EEF   D  + +WV S +K SD G++  TAG FY D +KDKG+QTSQDA+FY  S + E PFSN+ ++LV+QF VKHEQ IDCGGGY+K+   DLDQ + HG++ Y +MFGPDICG  TKKVHVIFNY GKNHLIKK+I CKDDEF+HLYTLIL  D TY+V ID EKVESG+ E+DWDFL PKKI DP A+KP DW D PK+ D  D KPEDW+KP+ IPDP AKKPEDW ++MDGEWE P I NPEY+G+WKPK+IDNP+YKG WVHPEIDNP+Y PD  +Y    IG +G DLWQVKSGT+FDN LITD+ + A+D G +TW  T + E+ MK + D
Sbjct:    1 MNTLSLFVGLIALYCVHAKIYFREEFLDGDEWRSRWVNSKHK-SDYGEWKLTAGNFYGDAEKDKGLQTSQDARFYAASARFE-PFSNEGKSLVIQFTVKHEQKIDCGGGYVKVFPSDLDQTDMHGDSSYYVMFGPDICGYTTKKVHVIFNYKGKNHLIKKEIKCKDDEFTHLYTLILNPDQTYQVKIDNEKVESGSLEEDWDFLPPKKIKDPEAKKPEDWDDRPKIDDPEDTKPEDWEKPEYIPDPDAKKPEDWQEDMDGEWEPPMISNPEYKGEWKPKQIDNPDYKGAWVHPEIDNPEYSPDANIYKFDSIGVLGLDLWQVKSGTVFDNFLITDDVKEAEDVGKETWGATKEPEQKMKQEQD 361

[Close]

BLAST of calreticulin-1 vs. Ensembl Medaka
Match: calr3b (calreticulin [Source:NCBI gene;Acc:101169735])

HSP 1 Score: 374.015 bits (959), Expect = 8.574e-127
Identity = 196/312 (62.82%), Postives = 237/312 (75.96%), Query Frame = 3

Query:  162 STADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNI-LITDEPE 1094
            S+ +   +WV S +K SD G++  TAG FY D +KDKG+QTSQDA+FY  S + E PFSN+ ++LV+QF VKHEQ IDCGGGY+K+   DLDQ + HG++ Y +MFGPDICG  TKKVHVIFNY GKNHLIKK+I CKDDEF+HLYTLIL  D TY+V ID EKVESG+ E+DWDFL PKKI DP A+KP DW D PK+ D  D KPEDW+KP+ IPDP AKKPEDW ++MDGEWE P I NPEY+G+WKPK+IDNP+YKG WVHPEIDNP+Y PD  +Y    IG +G DLWQ ++     +  L   EPE
Sbjct:    6 SSDEWRSRWVNSKHK-SDYGEWKLTAGNFYGDAEKDKGLQTSQDARFYAASARFE-PFSNEGKSLVIQFTVKHEQKIDCGGGYVKVFPSDLDQTDMHGDSSYYVMFGPDICGYTTKKVHVIFNYKGKNHLIKKEIKCKDDEFTHLYTLILNPDQTYQVKIDNEKVESGSLEEDWDFLPPKKIKDPEAKKPEDWDDRPKIDDPEDTKPEDWEKPEYIPDPDAKKPEDWQEDMDGEWEPPMISNPEYKGEWKPKQIDNPDYKGAWVHPEIDNPEYSPDANIYKFDSIGVLGLDLWQSRNRIKLCSFSLFLQEPE 315

[Close]

BLAST of calreticulin-1 vs. Ensembl Medaka
Match: ENSORLT00000021485.3 (calreticulin [Source:NCBI gene;Acc:101162115])

HSP 1 Score: 347.821 bits (891), Expect = 1.688e-116
Identity = 190/355 (53.52%), Postives = 237/355 (66.76%), Query Frame = 3

Query:   96 ILVILFSAIVNADPTIYLKEEFSTADSLK-KWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMK 1157
            +L+ + +  V A+ ++Y +E+F   D+ K +W+ES +K SD G+ + TAGKFY D +KDKG+QTSQDA FY  S + +  FSNK + LV+QF VKHEQ+IDCGGGYIKL   +L+Q++ HG++ Y IMFGPDICG GTKKVHVIFNY GKNHLI KDI CKDDEF+HLYTL++  DNTYEV ID +KVESGN E+DWDFL PKKI DP+A+KP DW D  K+PD +DKKPEDWDKP+ IPDP AKKPEDW              + E  G+W+P  I NP+YK                                  VKSGTIFDN LIT++P  A++ G  TW  T D E+ MK
Sbjct:    7 LLMAVCATSVLAESSVYFREQFEDGDAWKSRWIESKHK-SDYGQLVLTAGKFYGDGEKDKGLQTSQDAHFYASSARFDD-FSNKGQPLVIQFTVKHEQSIDCGGGYIKLFPSELNQEDMHGDSVYNIMFGPDICGPGTKKVHVIFNYKGKNHLINKDIRCKDDEFTHLYTLVVNPDNTYEVKIDNKKVESGNLEEDWDFLPPKKIKDPDAKKPEDWDDREKIPDPDDKKPEDWDKPENIPDPDAKKPEDW--------------DDEMDGEWEPPMIANPDYK----------------------------------VKSGTIFDNFLITNDPNLAEEVGNDTWGKTKDAERKMK 311

[Close]

BLAST of calreticulin-1 vs. Ensembl Medaka
Match: clgn (calnexin [Source:NCBI gene;Acc:101159642])

HSP 1 Score: 177.563 bits (449), Expect = 1.370e-48
Identity = 140/389 (35.99%), Postives = 193/389 (49.61%), Query Frame = 3

Query:  141 IYLKEEFSTADSLKKW-VESTYKGSDQGKFIYTAGKFYDDMDK------DKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMG--KDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNG-------KNHLIKKDIPCK---DDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDW--DFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWD-------------KPKT--------IPDPKAKKPXXXXXXXXXXXXAPK-------------------IDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTW 1124
            +Y  E F    SL +W +  T K     +     GK+  +  K      D G+     AK + I+  L KPF  +D  LVVQ++V  +  IDCGG YIKL+     L+ + FH  TPY IMFGPD CG    K+H IF +         + H  + D+  K    D+ +HLYTL+L  DN+YE+ ID   V  G+   D       PK+I+DP+  KP DW +  K+PD   +KP+DWD             KP+         + DP A+KPEDWD+EMDGEWEAP+                   I+NP+Y+G WK   +DN NY+G W   +I NPDY  D   +       +G +LW + S   FDN +IT + E A  +   +W
Sbjct:   97 VYFAETFDDG-SLDRWQLSKTMKEDADEEIAKYDGKWAVEQLKENKVPGDLGLVLKSRAKHHAIAAPLVKPFVFQDEPLVVQYEVNFQDGIDCGGAYIKLLSDTGSLNLEQFHDRTPYTIMFGPDKCG-EDYKLHFIFRHKNPLNKDMEEKHAKRADVDLKKFYTDKKTHLYTLVLNPDNSYEMFIDQSSVSRGSLLQDVVPPVNPPKEIDDPHDSKPDDWDERAKIPDPEAEKPDDWDEDAPAKVEDPDAVKPEGWLDDELEFVADPNAEKPEDWDEEMDGEWEAPQIPNPACETAPGCGEWKRPMINNPQYKGKWKAPLVDNSNYQGVWKPRKIQNPDYFEDLQPFRMTPFKALGLELWSMTSDIYFDNFIITSQKEVADRWASDSW 483

[Close]

BLAST of calreticulin-1 vs. Planmine SMEST
Match: SMESG000009012.1 (SMESG000009012.1)

HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0
Identity = 406/409 (99.27%), Postives = 408/409 (99.76%), Query Frame = 3

Query:   84 MMYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLDXXXXXXXXXXXXXXXXXXXXXPKVEEQDKAPESEEAESKDKVDHTEL 1310
            MMYYILVILF AIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPEDWDDEMDGEWEAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLDEE+RKRTEEEDKKKEATKQAEPKVEEQDKAPES+EAESKDKVDHTEL
Sbjct:    1 MMYYILVILFCAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPEDWDDEMDGEWEAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLDEEERKRTEEEDKKKEATKQAEPKVEEQDKAPESDEAESKDKVDHTEL 409

[Close]

BLAST of calreticulin-1 vs. Planmine SMEST
Match: SMESG000009012.1 (SMESG000009012.1)

HSP 1 Score: 743.421 bits (1918), Expect = 0.000e+0
Identity = 405/408 (99.26%), Postives = 407/408 (99.75%), Query Frame = 3

Query:   87 MYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLDXXXXXXXXXXXXXXXXXXXXXPKVEEQDKAPESEEAESKDKVDHTEL 1310
            MYYILVILF AIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPEDWDDEMDGEWEAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLDEE+RKRTEEEDKKKEATKQAEPKVEEQDKAPES+EAESKDKVDHTEL
Sbjct:    1 MYYILVILFCAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPEDWDDEMDGEWEAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLDEEERKRTEEEDKKKEATKQAEPKVEEQDKAPESDEAESKDKVDHTEL 408

[Close]

BLAST of calreticulin-1 vs. Planmine SMEST
Match: SMESG000077304.1 (SMESG000077304.1)

HSP 1 Score: 521.931 bits (1343), Expect = 0.000e+0
Identity = 266/362 (73.48%), Postives = 306/362 (84.53%), Query Frame = 3

Query:   84 MMYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            M  +I+ IL S  + A+PTIYL EEF T     +WVEST+KG+DQGKF +TAGKFY+D +KDKGIQTSQDAKFYGIS K +K FSN+ + LV+QFQVKHEQTIDCGGGY+KL+G + +Q  FHGETPY IMFGPDICG+ TKKVHVIFNY G+N LIKKDI CKDDEF+H+YTLI+  DNTYEVLID EKVESG+ EDDWDFL PKKI DPNA+KP DW D  K+ D  DKKPE+WDKPKTIPDPKAKKPEDWDDEMDGEWEAP+IDNPEY+G+WKPK+IDNP YKGPWVHPEI NPDYKPD  LY+  +IG +GFDLWQVKSGTIFDNIL+TD+P YAK +  +TW+VTADGEK MK+K D
Sbjct:    1 MKIFIMSILVSLAL-AEPTIYLNEEFLTESYKTQWVESTFKGADQGKFTWTAGKFYNDAEKDKGIQTSQDAKFYGISKKFDKAFSNEGKKLVIQFQVKHEQTIDCGGGYVKLVGSNFEQDKFHGETPYHIMFGPDICGLSTKKVHVIFNYKGQNLLIKKDIKCKDDEFTHVYTLIVNPDNTYEVLIDNEKVESGSLEDDWDFLAPKKIKDPNAKKPEDWEDNEKIDDITDKKPEEWDKPKTIPDPKAKKPEDWDDEMDGEWEAPQIDNPEYKGEWKPKQIDNPKYKGPWVHPEIPNPDYKPDTNLYVYKDIGAIGFDLWQVKSGTIFDNILLTDDPAYAKKYAEQTWKVTADGEKKMKDKQD 361

[Close]

BLAST of calreticulin-1 vs. Planmine SMEST
Match: SMESG000077304.1 (SMESG000077304.1)

HSP 1 Score: 516.538 bits (1329), Expect = 0.000e+0
Identity = 261/354 (73.73%), Postives = 301/354 (85.03%), Query Frame = 3

Query:  108 LFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEKAMKNKLD 1169
            +  ++  A+PTIYL EEF T     +WVEST+KG+DQGKF +TAGKFY+D +KDKGIQTSQDAKFYGIS K +K FSN+ + LV+QFQVKHEQTIDCGGGY+KL+G + +Q  FHGETPY IMFGPDICG+ TKKVHVIFNY G+N LIKKDI CKDDEF+H+YTLI+  DNTYEVLID EKVESG+ EDDWDFL PKKI DPNA+KP DW D  K+ D  DKKPE+WDKPKTIPDPKAKKPEDWDDEMDGEWEAP+IDNPEY+G+WKPK+IDNP YKGPWVHPEI NPDYKPD  LY+  +IG +GFDLWQVKSGTIFDNIL+TD+P YAK +  +TW+VTADGEK MK+K D
Sbjct:    3 ILVSLALAEPTIYLNEEFLTESYKTQWVESTFKGADQGKFTWTAGKFYNDAEKDKGIQTSQDAKFYGISKKFDKAFSNEGKKLVIQFQVKHEQTIDCGGGYVKLVGSNFEQDKFHGETPYHIMFGPDICGLSTKKVHVIFNYKGQNLLIKKDIKCKDDEFTHVYTLIVNPDNTYEVLIDNEKVESGSLEDDWDFLAPKKIKDPNAKKPEDWEDNEKIDDITDKKPEEWDKPKTIPDPKAKKPEDWDDEMDGEWEAPQIDNPEYKGEWKPKQIDNPKYKGPWVHPEIPNPDYKPDTNLYVYKDIGAIGFDLWQVKSGTIFDNILLTDDPAYAKKYAEQTWKVTADGEKKMKDKQD 356

[Close]

BLAST of calreticulin-1 vs. Planmine SMEST
Match: SMESG000039107.1 (SMESG000039107.1)

HSP 1 Score: 409.068 bits (1050), Expect = 2.329e-140
Identity = 210/350 (60.00%), Postives = 254/350 (72.57%), Query Frame = 3

Query:   99 LVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIYTAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHEQTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNYNGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDWDFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKPXXXXXXXXXXXXAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYKPDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVTADGEK 1148
            ++ L  A+ N    IY  EEF      ++WVESTY+G DQGKF    GK + D  K++G+QTSQ++KFYGI+ K + PF+N  + LV+Q+QVK ++ + CGGGYIKL+G D D  +FHG TPY+IMFGPDICG   K VHVI NY  K +L KKDI C DD+FSHLYTLI+  +NTY VLID  +VE G  EDDWD L PKK+ DPNA KP DWVD  K+ D ND KPE+WD+PKTIPD   KKP  WDDE+DG WE P I NP ++G+WKPK+IDNPNYKGPW+HPEIDNP Y  D+ LYL+  IG VGFD+WQV SGTIFDNIL+TD+PE A   G  TWRV    EK
Sbjct:    4 IIFLLFAMENIFCEIYFYEEFFDESYTERWVESTYRGIDQGKFQLGTGKHFGDYWKERGLQTSQNSKFYGIATKFKTPFNNSLKPLVIQYQVKMDEYVQCGGGYIKLLGTDFDPLSFHGHTPYKIMFGPDICGTNKKMVHVILNYKEKYYLTKKDIRCMDDKFSHLYTLIIFPNNTYSVLIDNNQVEGGKLEDDWDLLPPKKVKDPNAMKPVDWVDNDKIDDPNDFKPEEWDQPKTIPDNTVKKPNKWDDEVDGVWEPPLISNPNFKGEWKPKKIDNPNYKGPWIHPEIDNPHYYLDHNLYLQTSIGGVGFDIWQVVSGTIFDNILLTDDPETALRIGETTWRVALAEEK 353

The following BLAST results are available for this feature:

BLAST of calreticulin-1 vs. Ensembl Human
BLAST of calreticulin-1 vs. Ensembl Celegans
BLAST of calreticulin-1 vs. Ensembl Fly
BLAST of calreticulin-1 vs. Ensembl Zebrafish
BLAST of calreticulin-1 vs. Ensembl Xenopus
BLAST of calreticulin-1 vs. Ensembl Mouse
BLAST of calreticulin-1 vs. UniProt/SwissProt
BLAST of calreticulin-1 vs. TrEMBL
BLAST of calreticulin-1 vs. Ensembl Cavefish
BLAST of calreticulin-1 vs. Ensembl Sea Lamprey
BLAST of calreticulin-1 vs. Ensembl Yeast
BLAST of calreticulin-1 vs. Ensembl Nematostella
BLAST of calreticulin-1 vs. Ensembl Medaka
BLAST of calreticulin-1 vs. Planmine SMEST

BLAST of calreticulin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CALR	9.279e-149	65.13	calreticulin [Source:HGNC Symbol;Acc:HGNC:1455]	[more]
CALR3	1.854e-85	45.40	calreticulin 3 [Source:HGNC Symbol;Acc:HGNC:20407]	[more]
CALR	8.416e-75	69.95	calreticulin [Source:HGNC Symbol;Acc:HGNC:1455]	[more]
CLGN	5.518e-55	36.34	calmegin [Source:HGNC Symbol;Acc:HGNC:2060]	[more]
CLGN	5.518e-55	36.34	calmegin [Source:HGNC Symbol;Acc:HGNC:2060]	[more]

BLAST of calreticulin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
crt-1	2.583e-133	61.86	Calreticulin [Source:UniProtKB/Swiss-Prot;Acc:P27...	[more]
crt-1	2.583e-133	61.86	Calreticulin [Source:UniProtKB/Swiss-Prot;Acc:P27...	[more]
cnx-1	1.418e-45	36.23	Calnexin [Source:UniProtKB/Swiss-Prot;Acc:P34652]	[more]
cnx-1	4.779e-27	35.79	Calnexin [Source:UniProtKB/Swiss-Prot;Acc:P34652]	[more]

BLAST of calreticulin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Calr	1.721e-150	63.91	gene:FBgn0005585 transcript:FBtr0334618	[more]
Calr	1.721e-150	63.91	gene:FBgn0005585 transcript:FBtr0082103	[more]
Cnx99A	1.466e-48	35.92	gene:FBgn0015622 transcript:FBtr0085438	[more]
Cnx99A	1.466e-48	35.92	gene:FBgn0015622 transcript:FBtr0085437	[more]
Cnx99A	1.466e-48	35.92	gene:FBgn0015622 transcript:FBtr0110909	[more]

BLAST of calreticulin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
calr	5.044e-148	61.17	calreticulin [Source:ZFIN;Acc:ZDB-GENE-030131-4042...	[more]
calr3a	6.952e-143	61.60	calreticulin 3a [Source:ZFIN;Acc:ZDB-GENE-000208-1...	[more]
calr3b	1.054e-141	65.06	calreticulin 3b [Source:ZFIN;Acc:ZDB-GENE-030131-9...	[more]
clgn	7.577e-52	39.12	calmegin [Source:ZFIN;Acc:ZDB-GENE-060929-708]	[more]
canx	6.175e-51	36.32	calnexin [Source:ZFIN;Acc:ZDB-GENE-040426-2797]	[more]

BLAST of calreticulin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
calr	1.401e-148	62.22	calreticulin [Source:NCBI gene;Acc:407962]	[more]
calr	7.030e-140	64.16	calreticulin [Source:NCBI gene;Acc:407962]	[more]
calr	1.727e-139	60.45	calreticulin [Source:NCBI gene;Acc:407962]	[more]
calr	4.211e-139	64.24	calreticulin [Source:NCBI gene;Acc:407962]	[more]
calr	4.360e-139	64.24	calreticulin [Source:NCBI gene;Acc:407962]	[more]

BLAST of calreticulin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Calr	1.699e-151	66.28	calreticulin [Source:MGI Symbol;Acc:MGI:88252]	[more]
Calr4	4.213e-117	54.35	calreticulin 4 [Source:MGI Symbol;Acc:MGI:2140435]	[more]
Calr3	2.208e-79	43.18	calreticulin 3 [Source:MGI Symbol;Acc:MGI:1920566]	[more]
Calr4	6.989e-77	53.59	calreticulin 4 [Source:MGI Symbol;Acc:MGI:2140435]	[more]
Calr4	6.989e-77	53.59	calreticulin 4 [Source:MGI Symbol;Acc:MGI:2140435]	[more]

BLAST of calreticulin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P14211\|CALR_MOUSE	1.189e-150	66.28	Calreticulin OS=Mus musculus OX=10090 GN=Calr PE=1...	[more]
sp\|P18418\|CALR_RAT	1.146e-149	65.99	Calreticulin OS=Rattus norvegicus OX=10116 GN=Calr...	[more]
sp\|P29413\|CALR_DROME	1.725e-149	63.91	Calreticulin OS=Drosophila melanogaster OX=7227 GN...	[more]
sp\|P15253\|CALR_RABIT	6.708e-149	64.94	Calreticulin OS=Oryctolagus cuniculus OX=9986 GN=C...	[more]
sp\|P52193\|CALR_BOVIN	7.718e-149	65.23	Calreticulin OS=Bos taurus OX=9913 GN=CALR PE=1 SV...	[more]

BLAST of calreticulin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZIA6	0.000e+0	99.51	Calreticulin OS=Schmidtea mediterranea OX=79327 PE...	[more]
V9XRS2	0.000e+0	73.48	Calreticulin OS=Schmidtea mediterranea OX=79327 PE...	[more]
A0A267FN87	1.098e-160	70.85	Calreticulin OS=Macrostomum lignano OX=282301 GN=B...	[more]
A1YB06	1.004e-159	65.93	Calreticulin OS=Eisenia andrei OX=168636 PE=2 SV=1	[more]
A0A1I8I182	1.411e-158	66.48	Calreticulin OS=Macrostomum lignano OX=282301 PE=3...	[more]

BLAST of calreticulin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000019127.2	6.318e-153	64.90	calreticulin-like [Source:NCBI gene;Acc:103024869]	[more]
calr3b	3.637e-145	65.31	calreticulin-like [Source:NCBI gene;Acc:103040817]	[more]
ENSAMXT00000022283.2	1.780e-131	64.95	pep primary_assembly:Astyanax_mexicanus-2.0:5:2505...	[more]
clgn	3.397e-53	39.12	calnexin [Source:NCBI gene;Acc:103035256]	[more]
clgn	3.951e-53	39.12	calnexin [Source:NCBI gene;Acc:103035256]	[more]

BLAST of calreticulin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
calr	3.069e-146	64.74	calreticulin [Source:ZFIN;Acc:ZDB-GENE-030131-4042...	[more]
calr3b	2.218e-135	57.81	calreticulin 3b [Source:ZFIN;Acc:ZDB-GENE-030131-9...	[more]
si:ch211-274f20.2	1.318e-50	33.25	si:ch211-274f20.2 [Source:ZFIN;Acc:ZDB-GENE-091204...	[more]

BLAST of calreticulin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
CNE1	4.578e-26	28.64	Calnexin; integral membrane ER chaperone involved ...	[more]

BLAST of calreticulin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO48109	4.457e-155	69.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49786	7.093e-52	38.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of calreticulin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000003653.2	1.853e-146	60.28	calreticulin [Source:NCBI gene;Acc:101160304]	[more]
calr3b	1.042e-145	61.16	calreticulin [Source:NCBI gene;Acc:101169735]	[more]
calr3b	8.574e-127	62.82	calreticulin [Source:NCBI gene;Acc:101169735]	[more]
ENSORLT00000021485.3	1.688e-116	53.52	calreticulin [Source:NCBI gene;Acc:101162115]	[more]
clgn	1.370e-48	35.99	calnexin [Source:NCBI gene;Acc:101159642]	[more]

BLAST of calreticulin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000009012.1	0.000e+0	99.27	SMESG000009012.1	[more]
SMESG000009012.1	0.000e+0	99.26	SMESG000009012.1	[more]
SMESG000077304.1	0.000e+0	73.48	SMESG000077304.1	[more]
SMESG000077304.1	0.000e+0	73.73	SMESG000077304.1	[more]
SMESG000039107.1	2.329e-140	60.00	SMESG000039107.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30034254
GenBank	AFJ24760.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034254 ID=SMED30034254|Name=calreticulin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1429bp
CTTATATAATTGGCTGTTAGGCTTTACTTAACTAGTAACCAATCACAGTA
TTACACAGTAAGTCTACTGACGTAGAATTTTAAATGATGTATTACATTCT
TGTTATTCTCTTTTCTGCCATAGTAAATGCTGATCCGACTATTTATTTGA
AAGAAGAATTTAGTACAGCTGATTCATTAAAAAAATGGGTTGAATCCACT
TATAAAGGATCTGATCAAGGAAAATTCATTTATACCGCCGGAAAGTTTTA
TGATGATATGGATAAGGATAAAGGAATTCAGACCAGTCAAGATGCGAAAT
TTTATGGCATATCTTATAAATTAGAGAAACCCTTTTCGAATAAAGATAGA
ACATTGGTCGTTCAATTTCAAGTTAAACATGAACAAACAATTGATTGTGG
CGGAGGATACATTAAATTAATGGGTAAAGATCTGGATCAGAAAAATTTTC
ATGGAGAAACACCTTACGAAATAATGTTTGGTCCCGATATTTGTGGTATT
GGAACTAAAAAAGTCCATGTGATTTTCAATTATAATGGGAAAAATCATTT
GATTAAAAAAGATATTCCATGCAAAGATGATGAATTCAGTCATTTATATA
CATTAATTCTAAAATCAGATAACACATATGAAGTGTTAATAGATTTAGAG
AAAGTTGAAAGTGGAAATTTTGAAGATGACTGGGATTTTTTGCAGCCTAA
AAAGATAAATGATCCTAATGCACAAAAACCTGCAGATTGGGTCGATGAAC
CTAAAATGCCAGATGAGAATGATAAAAAACCTGAAGACTGGGATAAACCG
AAAACCATTCCCGATCCTAAAGCTAAAAAGCCTGAGGATTGGGATGATGA
AATGGATGGTGAGTGGGAGGCCCCAAAAATTGACAATCCTGAATATCGAG
GGGATTGGAAACCGAAAGAAATAGATAATCCTAACTATAAAGGCCCTTGG
GTGCATCCAGAAATCGACAATCCAGATTATAAGCCCGATAATACTCTTTA
TTTGCGTGGGGAAATCGGATATGTTGGTTTCGATCTGTGGCAGGTGAAGT
CCGGTACGATTTTCGACAACATTCTAATTACAGATGAACCGGAATATGCG
AAAGACTTCGGTTTGAAAACGTGGCGAGTGACTGCTGATGGAGAAAAAGC
AATGAAGAATAAATTGGACGAGGAAGACCGTAAACGCACCGAAGAAGAAG
ACAAGAAAAAGGAAGCTACAAAACAGGCCGAACCAAAAGTCGAGGAGCAA
GATAAAGCTCCAGAATCAGAAGAGGCAGAATCTAAGGACAAAGTCGACCA
CACCGAGCTGTAAAGGGCTATTCATTGAGATTTCTGGGCGTCGTTGTAAA
ATAAATTGACATTTATTTGTTTACGTATTTGTAATAAAGTTTCATTGGGA
ATAACGTGTTAAAAATTATAGAATTGTAT

protein sequence of SMED30034254-orf-1

>SMED30034254-orf-1 ID=SMED30034254-orf-1|Name=SMED30034254-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=410bp
MMYYILVILFSAIVNADPTIYLKEEFSTADSLKKWVESTYKGSDQGKFIY
TAGKFYDDMDKDKGIQTSQDAKFYGISYKLEKPFSNKDRTLVVQFQVKHE
QTIDCGGGYIKLMGKDLDQKNFHGETPYEIMFGPDICGIGTKKVHVIFNY
NGKNHLIKKDIPCKDDEFSHLYTLILKSDNTYEVLIDLEKVESGNFEDDW
DFLQPKKINDPNAQKPADWVDEPKMPDENDKKPEDWDKPKTIPDPKAKKP
EDWDDEMDGEWEAPKIDNPEYRGDWKPKEIDNPNYKGPWVHPEIDNPDYK
PDNTLYLRGEIGYVGFDLWQVKSGTIFDNILITDEPEYAKDFGLKTWRVT
ADGEKAMKNKLDEEDRKRTEEEDKKKEATKQAEPKVEEQDKAPESEEAES
KDKVDHTEL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005788	endoplasmic reticulum lumen
GO:0005783	endoplasmic reticulum

Vocabulary: **molecular function**
Term	Definition
GO:0046872	metal ion binding
GO:0051082	unfolded protein binding
GO:0005509	calcium ion binding
GO:0005515	protein binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000019	muscle progenitor cell
PLANA:0000020	protonephridia
PLANA:0000028	Category 2 cell
PLANA:0000034	epidermis
PLANA:0000035	Category 3 cell
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron
PLANA:0000120	progenitor cell
PLANA:0000484	secretory system
PLANA:0002032	epidermal cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR001580	Calret/calnex
IPR009169	Calreticulin
IPR013320	ConA-like_dom_sf
IPR018124	Calret/calnex_CS
IPR009033	Calreticulin/calnexin_P_dom_sf

Vocabulary: **biological process**
Term	Definition
GO:0006457	protein folding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 354..381
None	No IPR available	GENE3D	G3DSA:2.60.120.200		coord: 279..377 e-value: 1.1E-21 score: 79.4
None	No IPR available	GENE3D	G3DSA:2.60.120.200		coord: 19..208 e-value: 1.1E-71 score: 243.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 203..256
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 220..254
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 353..409
None	No IPR available	PANTHER	PTHR11073:SF16	CALRETICULIN	coord: 6..400
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..16 score: 0.814
IPR001580	Calreticulin/calnexin	PRINTS	PR00626	CALRETICULIN	coord: 100..118 score: 53.12 coord: 215..228 score: 47.84 coord: 126..142 score: 71.55 coord: 313..333 score: 60.47 coord: 280..299 score: 69.77 coord: 242..264 score: 79.37
IPR001580	Calreticulin/calnexin	PFAM	PF00262	Calreticulin	coord: 259..332 e-value: 9.1E-22 score: 77.4 coord: 24..257 e-value: 1.1E-61 score: 208.7
IPR001580	Calreticulin/calnexin	PANTHER	PTHR11073	CALRETICULIN AND CALNEXIN	coord: 6..400
IPR009169	Calreticulin	PIRSF	PIRSF002356	Calreticulin	coord: 1..409 e-value: 1.6E-184 score: 610.8
IPR009033	Calreticulin/calnexin, P domain superfamily	GENE3D	G3DSA:2.10.250.10		coord: 209..278 e-value: 1.2E-27 score: 98.0
IPR009033	Calreticulin/calnexin, P domain superfamily	SUPERFAMILY	SSF63887	P-domain of calnexin/calreticulin	coord: 201..315
IPR018124	Calreticulin/calnexin, conserved site	PROSITE	PS00803	CALRETICULIN_1	coord: 98..113
IPR018124	Calreticulin/calnexin, conserved site	PROSITE	PS00804	CALRETICULIN_2	coord: 130..138
IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	SUPERFAMILY	SSF49899	Concanavalin A-like lectins/glucanases	coord: 19..220