DIS3-like exonuclease 2

Query:  408 RGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLA-----TNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKK 2150
            + CP+  +   K Y+     C+I++W                               F             +++     +L  Y +    FS + +EC+P     + IP  E   R+D   +CI +IDP  A+D+DDAL  + ++ GN+ VGVHIADVSYF+   + LD  A  RA+S+YL  KV+PMLP +L E LCSLNP  DKL FS++  + P+G+I+ E F +++IR   KLSY+ A ++I   T+   A      +P +  E+  +++L L  +A  +R++R   GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  +   F    P +    A LR+HP P+    S   + C + G   +     ++ + + Q    + +       LT +    M +A Y C+       DP Q           F HY LNVPLYTHFTSPIRR+AD++VHR L+A +       ++     + A +CN  R+A++R+ +  TS++ A  + + G    + +++ I   +  VL+   G+  R     LA   S + ++  KK
Sbjct:  283 KDCPQDFVARPKDYANTLFICRIVDWKEDC--------------------------NFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP-WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLRQQRFVDGALRLDQLKLAFTLDHE----------TGLPQGCHIYEYRESNKLVEEFMLLANMAVAHKIHRAF----PEQ----ALLRRHPPPQTRMLSDLVEFCDQMGLPVDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSG---LLQDPAQ-----------FRHYALNVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDMAPDTLQKQADHCNDRRMASKRVQELSTSLFFAVLVKESGPLESEAMVMGILKQAFDVLVLRYGVQKRIYCNALA-LRSHHFQKVGKK 813          

Query:  408 RGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLA-----TNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKK 2150
            + CP+  +   K Y+     C+I++W                               F             +++     +L  Y +    FS + +EC+P     + IP  E   R+D   +CI +IDP  A+D+DDAL  + ++ GN+ VGVHIADVSYF+   + LD  A  RA+S+YL  KV+PMLP +L E LCSLNP  DKL FS++  + P+G+I+ E F +++IR   KLSY+ A ++I   T+   A      +P +  E+  +++L L  +A  +R++R   GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  +   F    P +    A LR+HP P+    S   + C + G   +     ++ + + Q    + +       LT +    M +A Y C+       DP Q           F HY LNVPLYTHFTSPIRR+AD++VHR L+A +       ++     + A +CN  R+A++R+ +  TS++ A  + + G    + +++ I   +  VL+   G+  R     LA   S + ++  KK
Sbjct:  283 KDCPQDFVARPKDYANTLFICRIVDWKEDC--------------------------NFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP-WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLRQQRFVDGALRLDQLKLAFTLDHE----------TGLPQGCHIYEYRESNKLVEEFMLLANMAVAHKIHRAF----PEQ----ALLRRHPPPQTRMLSDLVEFCDQMGLPVDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSG---LLQDPAQ-----------FRHYALNVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDMAPDTLQKQADHCNDRRMASKRVQELSTSLFFAVLVKESGPLESEAMVMGILKQAFDVLVLRYGVQKRIYCNALA-LRSHHFQKVGKK 813          

Query:  741 ERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLA-----TNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRR 1952
            E   R+D   +CI +IDP  A+D+DDAL  + ++ GN+ VGVHIADVSYF+   + LD  A  RA+S+YL  KV+PMLP +L E LCSLNP  DKL FS++  + P+G+I+ E F +++IR   KLSY+ A ++I   T+   A      +P +  E+  +++L L  +A  +R++R   GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  +   F    P +    A LR+HP P+    S   + C + G   +     ++ + + Q    + +       LT +    M +A Y C+       DP Q           F HY LNVPLYTHFTSPIRR+AD++VHR L+A +       ++     + A +CN  R+A++R
Sbjct:    2 EFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLRQQRFVDGALRLDQLKLAFTLDHE----------TGLPQGCHIYEYRESNKLVEEFMLLANMAVAHKIHRAF----PEQ----ALLRRHPPPQTRMLSDLVEFCDQMGLPVDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSG---LLQDPAQ-----------FRHYALNVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDMAPDTLQKQADHCNDRRMASKR 383          

Query:  300 LRPTGRIVSTITDLNSITFIGSL-----KPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALIN-GDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGE 1874
            L+PTGR+V  I   N   + G L     K    HL F P ++  P I IET +                 S  +G+ +  A+     +S        ++PN         V + ++    LL  + +  +PFS   +  +P     + I + +  NR+D    CI S+DP    DIDDALH + +  GN  VGVHIADVS+FI+P  ALD  +  R +++YL  K I M+P +LS +LCSL  + D+LAFS +  +N + EI+  KFTKSVI  K  L+Y +A   I+  + +  + T         SL  L+KLA +++KRR++ GAL ++ P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + AK +   F       SE  A LRKHP+P          + +      ++    S+ E ++Q +             T+  +N      A  C+      Q V   +  D  FHHYGL  P+YTHFTSPIRRYAD++VHR L+  I  +
Sbjct:  177 LKPTGRVVGIIKR-NWRPYCGMLSKSDIKESRRHL-FTPADKRIPRIRIETRQA----------------STLEGRRIIVAIDGWPRNS--------RYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMP--WSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITT---------SLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHD----------PIDLQTKELRETNSMVEEFMLLANISVAKKIHEEF-------SE-HALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESP-----------TFPYLNTLLRILATRCMM-----QAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGAD 636          

Query:  300 LRPTGRIVSTITDLNSITFIGSL-----KPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALIN-GDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGE 1874
            L+PTGR+V  I   N   + G L     K    HL F P ++  P I IET +                 S  +G+ +  A+     +S        ++PN         V + ++    LL  + +  +PFS   +  +P     + I + +  NR+D    CI S+DP    DIDDALH + +  GN  VGVHIADVS+FI+P  ALD  +  R +++YL  K I M+P +LS +LCSL  + D+LAFS +  +N + EI+  KFTKSVI  K  L+Y +A   I+  + +  + T         SL  L+KLA +++KRR++ GAL ++ P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + AK +   F           A LRKHP+P          + +      ++    S+ E ++Q +             T+  +N      A  C+      Q V   +  D  FHHYGL  P+YTHFTSPIRRYAD++VHR L+  I  +
Sbjct:  309 LKPTGRVVGIIKR-NWRPYCGMLSKSDIKESRRHL-FTPADKRIPRIRIETRQA----------------STLEGRRIIVAIDGWPRNS--------RYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMP--WSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITT---------SLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHD----------PIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEH--------ALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESP-----------TFPYLNTLLRILATRCMM-----QAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGAD 768          

Query:  678 FSDKDMECVP-ASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVS-----GGNYL-VGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALI-NGDTDSSLATNPHYEKA------VESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKAL---GLSFLTYINMNVAEYCCA-ENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRL-EAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHR 2090
            FSD+ +E +P  +AE + +P  E + R+DF ++ + +IDP  A+D+DDALH + +      G   L +GVHIADV++F+K  T LD  A  R +S YL   VIPMLP IL E LCSLNP  D+L+FS +  ++ + E+    F +SVIR + KL+Y+ A   I N + D +    P            E  L+L ++A V+R++R DSGAL I  P + F             D   +P G+    +  SN L+EEFMLLAN   AK +  NF           A LR HP P++       + C R GF  + +    +   + + Q            +S LT   M  A+Y C  E  LSF                +HH+ LNV  YTHFTSPIRRY D++VHRQL+A + G N     + + + E    CN +++A++  +D    +Y   +++Q G    + +++ +   S  VL+   G++ R
Sbjct:  307 FSDECLESLPITTAENWKVPDAEFEYRRDFRSDIVFTIDPKTARDLDDALHAKHIDDCDGKGTPGLEIGVHIADVTFFLKEGTELDKWASERGNSTYLSQTVIPMLPRILCEQLCSLNPGVDRLSFSTVFKMSYEAELYDVWFGRSVIRSRVKLAYEHAQDFIENPEKDFTCDELPDISDGNTPFEIKEKTLMLHRIAQVLRQKREDSGALRIELPRLKFAL-----------DEDKKPQGVSIYEIKDSNKLVEEFMLLANMEVAKKIAENFPEH--------ALLRNHPPPKEKMIKDVAEQCARIGFPLDGRTSGLLSTSLRKYQGKSRLDMCIRQVISSLTIKPMQQAKYFCTFEMPLSF----------------YHHFALNVDHYTHFTSPIRRYPDVIVHRQLAAAL-GYNERSERVPEEIQEICTRCNDTKLASKEASDESAMLYFGVFIHQTGPMKCQAVVLGVMDLSFDVLIVEYGVVKR 760          

Query:  363 SLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHE----RDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVE-SLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQ-IQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGEN 1877
            ++K    HL F P  R  P I IET++  +   Q  +I+   +H     K                      +P          +   ++    LL  + +   PFS+  ++C+P    E  + ++     R + +D T   I S+DP    DIDDALH + +    + VGVHIADV++F++P TA+D  A  R +++YL  + I MLP +LS +LCSL   E++ AFS +  +    +I S K+ KS+I+ K  L+Y++A  +I+         +P  +  V   L  L KL+ V+  RR  +GAL +    V F  + +    S T   + E   L       ++ ++EEFMLLAN + A+ +   +    P+     A LR+HP P K       ++ +  GF    +    + + +N+ + +  P     L  LT   M  A Y  A                  P   + H+GL   +YTHFTSPIRRYAD++VHR L+A I  ++
Sbjct:  373 TVKGARRHL-FCPAERLIPRIRIETEQAETLSQQ--RIVVAIDHWPRDSK----------------------YPLGHYVRSIGEMGSRETENEVLLLEHDIPHAPFSESVLDCLPREEWEPDLTENRGPLPRVDLRDLT---ICSVDPLGCTDIDDALHCKQIGEDLFEVGVHIADVTHFVRPGTAIDDEAALRGTTVYLCDRRIDMLPCLLSSNLCSLRGEEERYAFSCIWTMTSSADIQSVKYHKSLIKSKAALTYEKAQEIID---------DPKEQNDVALGLRGLMKLSKVLNARRTGNGALTLASSEVRFDMDWE----SRTPKKVMEKQHLD------THSMVEEFMLLANISVAEKILEEY----PD----CALLRRHPVPLKESYKPLVEAARHRGFEIIVESGKGLADSLNRCVDKKNPMLNRLLRMLTTRCMTQAVYFSAGTV---------------PVPQYQHFGLACAIYTHFTSPIRRYADVIVHRLLAAAIGADD 813          

Query:  363 SLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHE----RDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVE-SLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQ-IQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGEN 1877
            ++K    HL F P  R  P I IET++  +   Q  +I+   +H     K                      +P          +   ++    LL  + +   PFS+  ++C+P    E  + ++     R + +D T   I S+DP    DIDDALH + +    + VGVHIADV++F++P TA+D  A  R +++YL  + I MLP +LS +LCSL   E++ AFS +  +    +I S K+ KS+I+ K  L+Y++A  +I+         +P  +  V   L  L KL+ V+  RR  +GAL +    V F  + +    S T   + E   L       ++ ++EEFMLLAN + A+ +   +    P+     A LR+HP P K       ++ +  GF    +    + + +N+ + +  P     L  LT   M  A Y  A                  P   + H+GL   +YTHFTSPIRRYAD++VHR L+A I  ++
Sbjct:  373 TVKGARRHL-FCPAERLIPRIRIETEQAETLSQQ--RIVVAIDHWPRDSK----------------------YPLGHYVRSIGEMGSRETENEVLLLEHDIPHAPFSESVLDCLPREEWEPDLTENRGPLPRVDLRDLT---ICSVDPLGCTDIDDALHCKQIGEDLFEVGVHIADVTHFVRPGTAIDDEAALRGTTVYLCDRRIDMLPCLLSSNLCSLRGEEERYAFSCIWTMTSSADIQSVKYHKSLIKSKAALTYEKAQEIID---------DPKEQNDVALGLRGLMKLSKVLNARRTGNGALTLASSEVRFDMDWE----SRTPKKVMEKQHLD------THSMVEEFMLLANISVAEKILEEY----PD----CALLRRHPVPLKESYKPLVEAARHRGFEIIVESGKGLADSLNRCVDKKNPMLNRLLRMLTTRCMTQAVYFSAGTV---------------PVPQYQHFGLACAIYTHFTSPIRRYADVIVHRLLAAAIGADD 813          

Query:  306 PTGRIVSTITDLNSITFIGSLKP-----MNTHLMFWPYNRGCPEIHIETDKKYSADNQA--CKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRL--EAAHNCN 1928
            PTGRIV  I       + G L+P      N H+ F P +R  P I IET +     NQ     I  W  +S                          ++P+         + D+ +    +L  + +    FSD+ +  +P     + I   +   R D     I S+DP    DIDDALH + +  GN  VGVHIADVS+FI+P  ALD  A  R +++YL  K I M+P +LS +LCSL    ++ AFS +  ++ +  ++S++F KSVI+ K  ++Y++A  +I+  T  +        +  +SL  L++LA +++KRR+D+GAL++  P + F  +S+            EP  ++ K +  +N ++EEFMLLAN   A+ +   F       SE  A LR+HP P          S +  GF+    D+NS +E+ + + +    KA    F T I + +   C  +     +   Q+ +        F HYGL  P+YTHFTSPIRRY+DI+VHR L+A I  +++    L ++   E  HN N
Sbjct:  348 PTGRIVG-IVRRKWRQYCGILQPSLIEDTNRHI-FVPADRKIPRIRIETRQAAMLQNQRIIVTIDTWPRNS--------------------------RYPHGHFVRSLGPLGDMATENEVILLEHDVPHCKFSDEVLSFLPKMP--WTITDEDYSKRVDLRDLYICSVDPPGCTDIDDALHCKELPNGNLEVGVHIADVSHFIRPGNALDMEAAARGTTVYLVGKRIDMVPELLSSNLCSLVGGVERFAFSCVWEVDNEANVLSKRFHKSVIKSKRAMTYEEAQNIIDDATQQN--------EIAKSLRNLNRLAKILKKRRMDNGALVLASPEIRFQVDSETH----------EPLEVEVKQMRETNSMVEEFMLLANITVAEHIATEF-------SEC-AVLRRHPRPPPTNFDPLVKSARYQGFQV---DINSGLELSHSLDKCV--KADNPYFNTMIRI-LTTRCMMQAVYFISGSLQKEE--------FFHYGLAAPIYTHFTSPIRRYSDIMVHRLLAASIGADSTYAQLLDRKSNEELCHNLN 827          

Query:  306 PTGRIVSTITDLNSITFIGSLKP-----MNTHLMFWPYNRGCPEIHIETDKKYSADNQA--CKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRL--EAAHNCN 1928
            PTGRIV  I       + G L+P      N H+ F P +R  P I IET +     NQ     I  W  +S                          ++P+         + D+ +    +L  + +    FSD+ +  +P     + I   +   R D     I S+DP    DIDDALH + +  GN  VGVHIADVS+FI+P  ALD  A  R +++YL  K I M+P +LS +LCSL    ++ AFS +  ++ +  ++S++F KSVI+ K  ++Y++A  +I+  T  +        +  +SL  L++LA +++KRR+D+GAL++  P + F  +S+            EP  ++ K +  +N ++EEFMLLAN   A+ +   F       SE  A LR+HP P          S +  GF+    D+NS +E+ + + +    KA    F T I + +   C  +     +   Q+ +        F HYGL  P+YTHFTSPIRRY+DI+VHR L+A I  +++    L ++   E  HN N
Sbjct:  348 PTGRIVG-IVRRKWRQYCGILQPSLIEDTNRHI-FVPADRKIPRIRIETRQAAMLQNQRIIVTIDTWPRNS--------------------------RYPHGHFVRSLGPLGDMATENEVILLEHDVPHCKFSDEVLSFLPKMP--WTITDEDYSKRVDLRDLYICSVDPPGCTDIDDALHCKELPNGNLEVGVHIADVSHFIRPGNALDMEAAARGTTVYLVGKRIDMVPELLSSNLCSLVGGVERFAFSCVWEVDNEANVLSKRFHKSVIKSKRAMTYEEAQNIIDDATQQN--------EIAKSLRNLNRLAKILKKRRMDNGALVLASPEIRFQVDSETH----------EPLEVEVKQMRETNSMVEEFMLLANITVAEHIATEF-------SEC-AVLRRHPRPPPTNFDPLVKSARYQGFQV---DINSGLELSHSLDKCV--KADNPYFNTMIRI-LTTRCMMQAVYFISGSLQKEE--------FFHYGLAAPIYTHFTSPIRRYSDIMVHRLLAASIGADSTYAQLLDRKSNEELCHNLN 827          

Query:  279 FVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLM--FWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEA--LPTIYNHSLIFH--DKFQQFPNADSTHK----QAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEK--FTKSVIRPKFKLSYKQANALINGD----TDSSLAT-----NPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKA---LGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIK 1868
            FV  +TK     +IV TI+      F    K  +  L   F PY+   P +++  D        AC         +    LL+ A  L T  N   I        +  N D   K       ++D+K      + IY     P S +D+                   RKD    CI +IDP  A+D+DDA+ I+ +    Y +GVHI+DVS+F+  D  LD+    R++SIYL ++VI MLP  L    CSL P +DK AFS+   +N  G ++ +K  F ++VI    + +Y+ A  +I+      T++   T     NP  +     +L L  +A+ IRK R+D+GAL IN   + F  +              EP   + +    +N LIEEFMLLANQA A+ + ++F    P+     A LR HP P         +     GF  +     ++ E + ++    P+       LS L    M  A Y C+E      D                HY L++P+YTHFTSPIRRY DI+VHR L+A +K
Sbjct:  411 FVIAITKRTELRQIVGTIS------FTNPTKLCDDQLFYKFRPYDLRVPMVYVPKD--------ACAAHIGNKQQIDVSGLLYLAHILETDCNGHCIAELIQPVGRVGNLDDELKAILFHNGLRDIKPFEQRFIDIYSQPPPPISQEDLR-----------------QRKDLRKMCIFTIDPMTARDLDDAVSIEKLGDNEYEIGVHISDVSHFLIEDNELDNIVKERSTSIYLANEVIHMLPQSLCMR-CSLLPGQDKFAFSVFWRMNGKGVMLQKKPEFCRTVINSCSQFAYEHAQKIIDNPNERFTENDFPTILNGFNP--DDIRNRVLWLHDIASSIRKTRLDNGALTINNAKLRFLLDP----------ITGEPLSFEVEKQREANRLIEEFMLLANQAVARFIHDSF----PDI----AVLRNHPPPLIKSLKALREKLLALGFELDYSSSKALQESMVRLCNEAPNPVAMNACLSQLLMKPMARATYFCSEGKSEPAD--------------LWHYALSIPIYTHFTSPIRRYPDILVHRLLAAALK 898          

Query:  279 FVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLM--FWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEA--LPTIYNHSLIFH--DKFQQFPNADSTHK----QAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEK--FTKSVIRPKFKLSYKQANALINGD----TDSSLAT-----NPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKA---LGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIK 1868
            FV  +TK     +IV TI+      F    K  +  L   F PY+   P +++  D        AC         +    LL+ A  L T  N   I        +  N D   K       ++D+K      + IY     P S +D+                   RKD    CI +IDP  A+D+DDA+ I+ +    Y +GVHI+DVS+F+  D  LD+    R++SIYL ++VI MLP  L    CSL P +DK AFS+   +N  G ++ +K  F ++VI    + +Y+ A  +I+      T++   T     NP  +     +L L  +A+ IRK R+D+GAL IN   + F  +              EP   + +    +N LIEEFMLLANQA A+ + ++F    P+     A LR HP P         +     GF  +     ++ E + ++    P+       LS L    M  A Y C+E      D                HY L++P+YTHFTSPIRRY DI+VHR L+A +K
Sbjct:  423 FVIAITKRTELRQIVGTIS------FTNPTKLCDDQLFYKFRPYDLRVPMVYVPKD--------ACAAHIGNKQQIDVSGLLYLAHILETDCNGHCIAELIQPVGRVGNLDDELKAILFHNGLRDIKPFEQRFIDIYSQPPPPISQEDLR-----------------QRKDLRKMCIFTIDPMTARDLDDAVSIEKLGDNEYEIGVHISDVSHFLIEDNELDNIVKERSTSIYLANEVIHMLPQSLCMR-CSLLPGQDKFAFSVFWRMNGKGVMLQKKPEFCRTVINSCSQFAYEHAQKIIDNPNERFTENDFPTILNGFNP--DDIRNRVLWLHDIASSIRKTRLDNGALTINNAKLRFLLDP----------ITGEPLSFEVEKQREANRLIEEFMLLANQAVARFIHDSF----PD----IAVLRNHPPPLIKSLKALREKLLALGFELDYSSSKALQESMVRLCNEAPNPVAMNACLSQLLMKPMARATYFCSEGKSEPAD--------------LWHYALSIPIYTHFTSPIRRYPDILVHRLLAAALK 910          

Query:  519 FEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVK-------DLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-----DTDSSLATNPHYE--KAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAH----NCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHR 2090
            F + P  Y ++L F  +  Q+P ADS   +  +        +++     +L  Y +    F+++ + C+P     + IP HE   R+D   ECI +IDP  A+D+DDAL  + +S GN+ VGVHIADVSYF+K   ALD  A  RA+S+YL  KVIPMLP +L E LCSLNP  D+L FS++  ++P+G+I+SE F ++VI    KLSY  A ++I+        +   A +P++   +  E++L L  +A  +R +R + GAL +++  ++FT + +             P G        SN L+EEFMLLAN A    ++ ++        E+ A LR+HP P+        +   + G   +     ++   +N+    + + A     +T++    M +A Y CA               + D    F HY LNVPLYTHFTSPIRRYAD++VHR L A +    +CG  LS   E  H    +CN  + A++R+ +  + ++ A ++ + G    + +++ +   S  VL+   G+  R
Sbjct:  419 FTSRPGDYENTL-FICRITQWP-ADSNFAEGRLAKTLGQAGEIEPETEGILTEYGVDFSEFTEEVLNCLPQDLP-WSIPAHELSTRRDLRKECIFTIDPATARDLDDALSCKQLSDGNFEVGVHIADVSYFVKEGNALDELAGQRATSVYLVQKVIPMLPRLLCEELCSLNPLTDRLTFSVIWKLSPEGKILSEWFGRTVICSCIKLSYDHAQSMIDAPDKHFSPEELPACSPNHSIIEIQEAVLNLHNIAKQLRAQRFEGGALRLDQLKLSFTLDKES----------SMPQGCYVYQYRDSNKLVEEFMLLANMAVGHQIYRSY-------PEL-ALLRRHPPPQTKMVDDMQEFFDQMGLDIDFSSSGALHRSLNENLGDDEYTAARKEVITHMCSRPMQMAVYFCA-------------GALKDEKL-FRHYALNVPLYTHFTSPIRRYADVIVHRLLGASL----NCGPRLSVSGEEVHQQASHCNDRKTASKRVQELSSELFFAVFVKECGPLDSEAMVMGVLDQSFDVLVLRYGVQKR 924          

Query:  519 FEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVK-------DLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-----DTDSSLATNPHYE--KAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAI-------IKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHR 2090
            F + P  Y ++L F  +  Q+P ADS   +  +        +++     +L  Y +    F+++ + C+P     + IP HE   R+D   ECI +IDP  A+D+DDAL  + +S GN+ VGVHIADVSYF+K   ALD  A  RA+S+YL  KVIPMLP +L E LCSLNP  D+L FS++  ++P+G+I+SE F ++VI    KLSY  A ++I+        +   A +P++   +  E++L L  +A  +R +R + GAL +++  ++FT + +             P G        SN L+EEFMLLAN A    ++ ++        E+ A LR+HP P+        +   + G   +     ++   +N+    + + A     +T++    M +A Y CA               + D    F HY LNVPLYTHFTSPIRRYAD++VHR L  +       +KGE        +  + A +CN  + A++R+ +  + ++ A ++ + G    + +++ +   S  VL+   G+  R
Sbjct:  403 FTSRPGDYENTL-FICRITQWP-ADSNFAEGRLAKTLGQAGEIEPETEGILTEYGVDFSEFTEEVLNCLPQDLP-WSIPAHELSTRRDLRKECIFTIDPATARDLDDALSCKQLSDGNFEVGVHIADVSYFVKEGNALDELAGQRATSVYLVQKVIPMLPRLLCEELCSLNPLTDRLTFSVIWKLSPEGKILSEWFGRTVICSCIKLSYDHAQSMIDAPDKHFSPEELPACSPNHSIIEIQEAVLNLHNIAKQLRAQRFEGGALRLDQLKLSFTLDKES----------SMPQGCYVYQYRDSNKLVEEFMLLANMAVGHQIYRSY-------PEL-ALLRRHPPPQTKMVDDMQEFFDQMGLDIDFSSSGALHRSLNENLGDDEYTAARKEVITHMCSRPMQMAVYFCA-------------GALKDEKL-FRHYALNVPLYTHFTSPIRRYADVIVHRLLGLLYCWVRGHVKGE--------EVHQQASHCNDRKTASKRVQELSSELFFAVFVKECGPLDSEAMVMGVLDQSFDVLVLRYGVQKR 907          

Query:  300 LRPTGRIVSTITDLNSITFIGSL-----KPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAA--HNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGI 2081
            L+PTGR+V  I   N   F G L     K    HL F P +R  P I IET        QA  +I         G+ +  A+     +S        ++PN           D ++    LL  + +  +PFS   +  +P     + I + +   R D    C+ S+DP    DIDDALH + +  GN  VGVHIADVS+FI+P  ALD  A +R +++YL  K I M+P +LS +LCSL  N ++LAFS +  +N   EII   FTKSVI  K  L+Y +A   I+  T +   T        +SL  L+KLA +++ +R+D GAL ++ P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ +++ F       SE  A LRKHP+P        YD   +A    +S+DL            T+  KAL  S       N A +      L+     Q V   +  D  FHHYGL  P+YTHFTSPIRRYADI+VHR L+  I  +++    + +  ++A  +N N      +       + +   +    G    +G ++ +  N++I+L+   G+
Sbjct:  336 LKPTGRVVGIIKR-NWRPFCGMLAQSQIKEATRHL-FTPADRRIPRIRIET-------RQAATLI---------GQRIMVAIDGWPKNS--------RYPNGHFVKNLGTAGDKETETEVLLLEHDVPHQPFSQAVLSFLPKMP--WGITEEDLKVRADLRHLCVCSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQEAANRGTTVYLCGKRIDMVPELLSSNLCSLRSNVERLAFSCIWEMNHKAEIIKTHFTKSVINSKASLTYAEAQMRIDDTTMNDDIT--------KSLRGLNKLAKILKAQRIDKGALTLSSPEVRFHIDSETHD----------PIDLQTKELMETNSMVEEFMLLANISVAQKIYDEF-------SEC-ALLRKHPAPPPSN----YDILIKAA---KSRDLEI---------HTDSAKALADSLNNATIENFAYFNTLLRILATRCMMQAVYFCSGMDSDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAINADSTYPDLMDKHKQSALCNNINYRHKMAQYAQRASVAFHTQLFFKNKGIINEEGFILFVRKNAIIILIPKFGL 866          

Query:  300 LRPTGRIVSTITDLNSITFIGSL-----KPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAA--HNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGI 2081
            L+PTGR+V  I   N   F G L     K    HL F P +R  P I IET        QA  +I         G+ +  A+     +S        ++PN           D ++    LL  + +  +PFS   +  +P     + I + +   R D    C+ S+DP    DIDDALH + +  GN  VGVHIADVS+FI+P  ALD  A +R +++YL  K I M+P +LS +LCSL  N ++LAFS +  +N   EII   FTKSVI  K  L+Y +A   I+  T +   T        +SL  L+KLA +++ +R+D GAL ++ P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ +++ F       SE  A LRKHP+P        YD   +A    +S+DL            T+  KAL  S       N A +      L+     Q V   +  D  FHHYGL  P+YTHFTSPIRRYADI+VHR L+  I  +++    + +  ++A  +N N      +       + +   +    G    +G ++ +  N++I+L+   G+
Sbjct:  336 LKPTGRVVGIIKR-NWRPFCGMLAQSQIKEATRHL-FTPADRRIPRIRIET-------RQAATLI---------GQRIMVAIDGWPKNS--------RYPNGHFVKNLGTAGDKETETEVLLLEHDVPHQPFSQAVLSFLPKMP--WGITEEDLKVRADLRHLCVCSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQEAANRGTTVYLCGKRIDMVPELLSSNLCSLRSNVERLAFSCIWEMNHKAEIIKTHFTKSVINSKASLTYAEAQMRIDDTTMNDDIT--------KSLRGLNKLAKILKAQRIDKGALTLSSPEVRFHIDSETHD----------PIDLQTKELMETNSMVEEFMLLANISVAQKIYDEF-------SEC-ALLRKHPAPPPSN----YDILIKAA---KSRDLEI---------HTDSAKALADSLNNATIENFAYFNTLLRILATRCMMQAVYFCSGMDSDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAINADSTYPDLMDKHKQSALCNNINYRHKMAQYAQRASVAFHTQLFFKNKGIINEEGFILFVRKNAIIILIPKFGL 866          

Query:  123 NIHIISLLPISEWLFREKFRVLNFNESKFSWYLKNSFPEKNSLIDKPLNSYLFVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFH-DKFQQ---FPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEE--FVIPQHERDNRKDFT-AECXXXXXXXXXXXXXXALHIQAVSGGNYL-VGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDG-EIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNP--------HYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQ-IQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGEN----SCGISLSQRLE--AAHNCNVSRIAN 1946
            ++ +I LLP +EW    K R +   E +                ++PL      +  ++  PTGR+V  I   N   ++ +L P                   E  +  S ++Q   ++ W ++ +PK ++  +    + +  +I   D ++    +PN           +L++ I  +L    +   PFS+  +  +P + EE  + +  +E  +R+D   +  + SIDP   +D+DD L ++ + GG  L +GVHIADV++F++  +  D  A  RA++ YL  +   MLP +LS  LCSL    D+ A S++  ++ +  E+ S  F +++IR  ++L Y+ A +L+NG+       NP           + +++L  L ++A  +R +R   GAL +    V    +    +  N    +P       K     +  + E M+ AN   A+ +  +F    P+     A LR HP P++   +   DS K  GF  +++   ++ + + + +   +P     L  +    M+ A Y    +C               P+  ++HYGL +  YTHFTSPIRRYAD++VHR L A ++ E     S  ++ ++ LE  A H  N +R A 
Sbjct:  286 DVVVIELLPRNEW----KGRTMALTEGQGE--------------ERPLE-----DTQSQPMPTGRVVG-ILQRNWRDYVVTLPPF------------------EEMQSQSRNSQKILVVPW-DYRIPKIRISTQQAEALQDQRVIVRLDSWESTSVYPNGHFVRVLGKSGELETEIQTILVENCIHVPPFSEAQLREMPVNTEENPWQMDSNEVSSRRDLRDSHLVFSIDPKGCEDVDDTLSVRTLPGGKRLELGVHIADVTHFVREGSLTDLEARSRATTYYLADRRYDMLPAVLSADLCSLLGGVDRYAMSVLWELDAETLEVCSVWFGRTLIRSSYQLHYELAQSLLNGEEVEVPELNPLKGSQRDQKMSELLQALETLTRVARHLRAQRDKGGALELEGVEVRAQLD----EEKNITALVP-------KQPLEVHETVAECMIYANHWVARKIQESF----PHH----ALLRHHPPPKQEFFNHLIDSAKAHGFSIDTRSNRALADSLERAVDPRDPLVNRLLRMMATQAMSNALYFSTGSC---------------PEEQYYHYGLALARYTHFTSPIRRYADVIVHRLLMAAVQLEKDESPSKALACNKELEELAQHINNKNRAAQ 840          

Query:  303 RPTGRIVSTITDLNSITFIGSLKPM----NTHLMFWPYNRGCPEIHIETDKKYSADNQ--ACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQET-EPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNC---NVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKKNT 2156
            +P+G++V  I   N   + G L       +T  +F P  R  P I IET +  + + Q     +  W  +S                          ++PN           D ++    LL  + +  +PFS   +  +P     + I   +  NR D     + S+DP    DIDDALH + +  G   VGVHIADVS+FI+P  ALD  + +R +++YL  K I M+P +LS +LCSL  N D+LAFS +  ++ +  I++ KFTKSVI  K  L+Y +A   I+    +        ++  +SL +L+KLA +++KRR+D+GAL ++ P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ +++ F       SE  A LRKHPSP        YD   +A    +SK+L+   +    + ++ +  ++ G  +     MN      A  C+      Q V   +  D  FHHYGL  P+YTHFTSPIRRYADI+VHR L A+  G +S    L+ + + A  C   N      +       + +   +    G    +G ++ +  N+++VL+   G+             + + E+K KK T
Sbjct:    4 KPSGQVVGIIKR-NWRPYCGMLSKSQIKESTRHLFTPAERRIPRIRIETRQASTLEGQRIIVAVDGWPRNS--------------------------RYPNGHFVKSLGTAGDKETETEVLLLEHDVPHQPFSQAVLSFLPKMP--WTITPEDMKNRIDLRHLYVCSVDPPGCTDIDDALHCRELENGTLEVGVHIADVSHFIRPGNALDQESSNRGTTVYLCDKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEVDENANILNTKFTKSVINSKASLTYAEAQMRIDSPNMN--------DEITQSLRLLNKLAKILKKRRIDNGALTLSSPEVRFHMDSETHD----------PIDLQTKELKETNSMVEEFMLLANISVAQKIYDEF-------SEY-ALLRKHPSPPPAN----YDILVKAA---KSKNLDIKTDSAKALADSLDKAESPGFPY-----MNTLLRILATRCMM-----QAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLL-AVAVGADSTYPDLTDKHKIADICKNINFRHKMAQYSQRASVAFHTQLFFKNRGIVNEEGFILFVRKNAIVVLIPKFGL-----------EGTVFFEEKDKKKT 547          

Query:  303 RPTGRIVSTITDLNSITFIGSLKPM----NTHLMFWPYNRGCPEIHIETDKKYSADNQ--ACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQET-EPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNC---NVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKKNT 2156
            +P+G++V  I   N   + G L       +T  +F P  R  P I IET +  + + Q     +  W  +S                          ++PN           D ++    LL  + +  +PFS   +  +P     + I   +  NR D     + S+DP    DIDDALH + +  G   VGVHIADVS+FI+P  ALD  + +R +++YL  K I M+P +LS +LCSL  N D+LAFS +  ++ +  I++ KFTKSVI  K  L+Y +A   I+    +        ++  +SL +L+KLA +++KRR+D+GAL ++ P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ +++ F       SE  A LRKHPSP        YD   +A    +SK+L+   +    + ++ +  ++ G  +     MN      A  C+      Q V   +  D  FHHYGL  P+YTHFTSPIRRYADI+VHR L A+  G +S    L+ + + A  C   N      +       + +   +    G    +G ++ +  N+++VL+   G+             + + E+K KK T
Sbjct:   10 KPSGQVVGIIKR-NWRPYCGMLSKSQIKESTRHLFTPAERRIPRIRIETRQASTLEGQRIIVAVDGWPRNS--------------------------RYPNGHFVKSLGTAGDKETETEVLLLEHDVPHQPFSQAVLSFLPKMP--WTITPEDMKNRIDLRHLYVCSVDPPGCTDIDDALHCRELENGTLEVGVHIADVSHFIRPGNALDQESSNRGTTVYLCDKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEVDENANILNTKFTKSVINSKASLTYAEAQMRIDSPNMN--------DEITQSLRLLNKLAKILKKRRIDNGALTLSSPEVRFHMDSETHD----------PIDLQTKELKETNSMVEEFMLLANISVAQKIYDEF-------SEY-ALLRKHPSPPPAN----YDILVKAA---KSKNLDIKTDSAKALADSLDKAESPGFPY-----MNTLLRILATRCMM-----QAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADIIVHRLL-AVAVGADSTYPDLTDKHKIADICKNINFRHKMAQYSQRASVAFHTQLFFKNRGIVNEEGFILFVRKNAIVVLIPKFGL-----------EGTVFFEEKDKKKT 553          

Query:  819 ALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-----DTDSSLATNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEA----AHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKK 2150
            AL  + +  GN+ VGVHIADVSYF+   +ALD  A  RA+S+YL  KVIPMLP +L E LCSLNP  D+L FS++  I P GEI+ E F +SVI    KLSY  A  +IN      +       +P +   +  +++L L  +A  +RK+R D GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  ++  F    P E    A LR+HP P+    +   + C + G + +     ++ + +N   ET+ + A     LT +    M +A Y C                + D    FHHY LNVPLYTHFTSPIRR+AD++VHR L+A +     CG  L    E     A +CN  + A++R+ +    ++ + ++ + G    + +++ +   +  V++   G+  R     L P  + + +Q  K+
Sbjct:  226 ALSCKPLPDGNFEVGVHIADVSYFVAEGSALDIMASERATSVYLVQKVIPMLPRLLCEELCSLNPMTDRLTFSVIWKITPQGEILDEWFGRSVICSCVKLSYDHAQNMINHPDKKIEQHELPPVSPQHTINEIHQAVLNLHLIAQNLRKQRFDDGALRLDQLKLTFTLDKES----------GLPQGCYIYQYRDSNKLVEEFMLLANMAVAHHIYRRF----PEE----ALLRRHPPPQTKMLNDLIEFCDQMGLQLDFSSSGTLHKSLNDQFETDEYSAARKEVLTNMCSRPMQMAVYFCT-------------GALKDETL-FHHYALNVPLYTHFTSPIRRFADVIVHRLLAASL----GCGPPLKMPKEVIQKQADHCNDRKTASKRVQELSAELFFSVFVKECGPLESEAMVMGVLNEAFDVIVLRFGVQKRIYCNSL-PLVNSHFQQVGKR 646          

Query:  819 ALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-----DTDSSLATNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEA----AHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKK 2150
            AL  + +  GN+ VGVHIADVSYF+   +ALD  A  RA+S+YL  KVIPMLP +L E LCSLNP  D+L FS++  I P GEI+ E F +SVI    KLSY  A  +IN      +       +P +   +  +++L L  +A  +RK+R D GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  ++  F    P E    A LR+HP P+    +   + C + G + +     ++ + +N   ET+ + A     LT +    M +A Y C                + D    FHHY LNVPLYTHFTSPIRR+AD++VHR L+A +     CG  L    E     A +CN  + A++R+ +    ++ + ++ + G    + +++ +   +  V++   G+  R     L P  + + +Q  K+
Sbjct:  342 ALSCKPLPDGNFEVGVHIADVSYFVAEGSALDIMASERATSVYLVQKVIPMLPRLLCEELCSLNPMTDRLTFSVIWKITPQGEILDEWFGRSVICSCVKLSYDHAQNMINHPDKKIEQHELPPVSPQHTINEIHQAVLNLHLIAQNLRKQRFDDGALRLDQLKLTFTLDKES----------GLPQGCYIYQYRDSNKLVEEFMLLANMAVAHHIYRRF----PEE----ALLRRHPPPQTKMLNDLIEFCDQMGLQLDFSSSGTLHKSLNDQFETDEYSAARKEVLTNMCSRPMQMAVYFCT-------------GALKDETL-FHHYALNVPLYTHFTSPIRRFADVIVHRLLAASL----GCGPPLKMPKEVIQKQADHCNDRKTASKRVQELSAELFFSVFVKECGPLESEAMVMGVLNEAFDVIVLRFGVQKRIYCNSL-PLVNSHFQQVGKR 762          

Query:  819 ALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-----DTDSSLATNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKK 2150
            AL  + +  GN+ VGVHIADVSYF+   +ALD  A  RA+S+YL  KVIPMLP +L E LCSLNP  D+L FS++  I P GEI+ E F +SVI    KLSY  A  +IN      +       +P +   +  +++L L  +A  +RK+R D GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  ++  F    P E    A LR+HP P+    +   + C + G + +     ++ + +N   ET+ + A     LT +    M +A Y C                + D    FHHY LNVPLYTHFTSPIRR+AD++VHR L+A          SL    + A +CN  + A++R+ +    ++ + ++ + G    + +++ +   +  V++   G+  R     L P  + + +Q  K+
Sbjct:  264 ALSCKPLPDGNFEVGVHIADVSYFVAEGSALDIMASERATSVYLVQKVIPMLPRLLCEELCSLNPMTDRLTFSVIWKITPQGEILDEWFGRSVICSCVKLSYDHAQNMINHPDKKIEQHELPPVSPQHTINEIHQAVLNLHLIAQNLRKQRFDDGALRLDQLKLTFTLDKES----------GLPQGCYIYQYRDSNKLVEEFMLLANMAVAHHIYRRF----PEE----ALLRRHPPPQTKMLNDLIEFCDQMGLQLDFSSSGTLHKSLNDQFETDEYSAARKEVLTNMCSRPMQMAVYFC-------------TGALKDETL-FHHYALNVPLYTHFTSPIRRFADVIVHRLLAA----------SLEVIQKQADHCNDRKTASKRVQELSAELFFSVFVKECGPLESEAMVMGVLNEAFDVIVLRFGVQKRIYCNSL-PLVNSHFQQVGKR 674          

Query:  621 DLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDS-------SLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELA 2111
            +++     +L  Y +    FS + +EC+P S   + IP  E   R+D   +CI +IDP  A+D+DDAL  + ++ G + VGVHIADVSYF+   ++LD  A  RA+S+YL  KV+PMLP +L E LCSLNP  DKL FS++  + P+G+I+ E F +++IR   KLSY  A ++I   T+         ++     E+  +++L L  +A  +R++R   GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  +F  F    P +    A LR+HP P+    S   + C + G   +     ++ + + +    + +       LT +    M +A Y C+       D EQ           F HY LNVPLYTHFTSPIRR+AD++VHR L+A +       +      + A +CN  R+A++R+ +    ++ A  + + G    + +++ +   +  VL+   G+  R     LA
Sbjct:  326 EIEPETEGILTEYGVDFSDFSSEVLECLPQSLP-WTIPPDEVGKRRDLRKDCIFTIDPSTARDLDDALACRRLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMTDKLTFSVIWKLTPEGKILEEWFGRTIIRSCTKLSYDHAQSMIENPTEKIPEEELPPISPEHSVEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLKLAFTLDHE----------TGLPQGCHIYEYRDSNKLVEEFMLLANMAVAHKIFRTF----PEQ----ALLRRHPPPQTKMLSDLVEFCDQMGLPMDVSSAGALNKSLTKTFGDDKYSLARKEVLTNMYSRPMQMALYFCSG---MLQDQEQ-----------FRHYALNVPLYTHFTSPIRRFADVIVHRLLAAALGYSEQPDVEPDTLQKQADHCNDRRMASKRVQELSIGLFFAVLVKESGPLESEAMVMGVLNQAFDVLVLRFGVQKRIYCNALA 799          

Query:  621 DLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDS-------SLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELA 2111
            +++     +L  Y +    FS + +EC+P S   + IP  E   R+D   +CI +IDP  A+D+DDAL  + ++ G + VGVHIADVSYF+   ++LD  A  RA+S+YL  KV+PMLP +L E LCSLNP  DKL FS++  + P+G+I+ E F +++IR   KLSY  A ++I   T+         ++     E+  +++L L  +A  +R++R   GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  +F  F    P +    A LR+HP P+    S   + C + G   +     ++ + + +    + +       LT +    M +A Y C+       D EQ           F HY LNVPLYTHFTSPIRR+AD++VHR L+A +       +      + A +CN  R+A++R+ +    ++ A  + + G    + +++ +   +  VL+   G+  R     LA
Sbjct:  340 EIEPETEGILTEYGVDFSDFSSEVLECLPQSLP-WTIPPDEVGKRRDLRKDCIFTIDPSTARDLDDALACRRLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMTDKLTFSVIWKLTPEGKILEEWFGRTIIRSCTKLSYDHAQSMIENPTEKIPEEELPPISPEHSVEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLKLAFTLDHE----------TGLPQGCHIYEYRDSNKLVEEFMLLANMAVAHKIFRTF----PEQ----ALLRRHPPPQTKMLSDLVEFCDQMGLPMDVSSAGALNKSLTKTFGDDKYSLARKEVLTNMYSRPMQMALYFCSG---MLQDQEQ-----------FRHYALNVPLYTHFTSPIRRFADVIVHRLLAAALGYSEQPDVEPDTLQKQADHCNDRRMASKRVQELSIGLFFAVLVKESGPLESEAMVMGVLNQAFDVLVLRFGVQKRIYCNALA 813          

Query:  300 LRPTGRIVSTITDLNSITFIGSL-----KPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETE-PHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGE 1874
            LRPTGR+V  I   N   + G L     K    HL F P ++  P I IET        QA         S  +G+ +  A+     +S        ++PN         V + ++    LL  + +  +PFS   +  +P     + I + +  NR+D    C+ S+DP    DIDDALH + +S GN  VGVHIADVS+FI+P  ALD  +  R +++YL  K I M+P +LS +LCSL  N D+LAFS +  +N + EI+  +FTKSVI  K  L+Y +A   I+     S A N   +    SL  L++LA +++K R++ GAL ++ P + F  +S+  D          P  LQ K L  +N ++EEFMLLAN + AK +   F           A LRKHP+P          + K    + ++    S+ + +++ +  + P+    L  L    M  A Y C+              + ND    FHHYGL  P+YTHFTSPIRRYADI+VHR L+  I  +
Sbjct:  339 LRPTGRVVGIIKR-NWRPYCGMLSKSDIKESRRHL-FTPADKRIPRIRIET-------RQA---------SALEGRRIIVAIDGWPRNS--------RYPNGHFVKNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPRMP--WSITEEDMKNREDLRHLCVCSVDPPGCTDIDDALHCRELSNGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKASLTYAEAQMRID-----SAAMN---DDITTSLRGLNQLAKILKKGRIEKGALTLSSPEIRFHMDSETHD----------PIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEH--------ALLRKHPAPPPSNYDILVKAAKSKNLQIKTDTAKSLADSLDRAESPDFPYLNTLLRILATRCMMQAVYFCS-------------GMDND----FHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGAD 798          

Query:  579 FPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEE---FVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDG-EIISEKFTKSVIRPKFKLSYKQANALINGDTD-----------SSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQE-TEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGIS----LSQRLE--AAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWR-----LVKGILINITGNSVIVLLTSSGI 2081
            +PN         + DL+  I+ +L    ++  PFS+  M  +P +  E    V P+ E++ +   T   + SIDP   +D+DD L ++ ++ GN  +GVHIADV++F+ P++ +D  A  RA++ YL  +   MLP ILS  LCSL    D+ A S+M  ++    EI    + +++IR  +KL Y+ A  L++G+                +     E+ V ++  L  +A  IR +R   GAL +    V    +    D  N  D IP       K     +  + E M+LAN   AK ++ +F    P++    A LR+HP P +   S   +  K  GF  +++   ++ + ++   +  +P     L  +    M+ A Y    +C      E+E          FHHYGL +  YTHFTSPIRRY+DIVVHR L A I  +    I      ++ LE    H  N +R A R    + T ++   Y            +  G++ +I  N V+V +   GI
Sbjct:  322 YPNGHFVRVLGRIGDLEGEIATILVENSISVVPFSEAQMCEMPVNTPENPWKVSPKEEQERKDLRTTHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPELKALDKQSQQAKLEELVWAIGKLTDIARHIRAKRDRCGALELEGVEVRVQLD----DKKNIRDLIP-------KQPLEVHETVAECMILANHWVAKKIWESF----PHQ----ALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDSANDPKDPLVNKLLRSMATQAMSNALYFSTGSC-----AEEE----------FHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKENLFSNKNLEELCRHINNRNRAAQRSQKQS-TELFQCMYFKDRDAETEERCIADGVIYSIRTNGVLVFIPRFGI 814          

Query:  579 FPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEE---FVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDG-EIISEKFTKSVIRPKFKLSYKQANALINGDTD-----------SSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQE-TEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGIS----LSQRLE--AAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWR-----LVKGILINITGNSVIVLLTSSGI 2081
            +PN         + DL+  I+ +L    ++  PFS+  M  +P +  E    V P+ E++ +   T   + SIDP   +D+DD L ++ ++ GN  +GVHIADV++F+ P++ +D  A  RA++ YL  +   MLP ILS  LCSL    D+ A S+M  ++    EI    + +++IR  +KL Y+ A  L++G+                +     E+ V ++  L  +A  IR +R   GAL +    V    +    D  N  D IP       K     +  + E M+LAN   AK ++ +F    P++    A LR+HP P +   S   +  K  GF  +++   ++ + ++   +  +P     L  +    M+ A Y    +C      E+E          FHHYGL +  YTHFTSPIRRY+DIVVHR L A I  +    I      ++ LE    H  N +R A R    + T ++   Y            +  G++ +I  N V+V +   GI
Sbjct:  322 YPNGHFVRVLGRIGDLEGEIATILVENSISVVPFSEAQMCEMPVNTPENPWKVSPKEEQERKDLRTTHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPELKALDKQSQQAKLEELVWAIGKLTDIARHIRAKRDRCGALELEGVEVRVQLD----DKKNIRDLIP-------KQPLEVHETVAECMILANHWVAKKIWESF----PHQ----ALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDSANDPKDPLVNKLLRSMATQAMSNALYFSTGSC-----AEEE----------FHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKENLFSNKNLEELCRHINNRNRAAQRSQKQS-TELFQCMYFKDRDAETEERCIADGVIYSIRTNGVLVFIPRFGI 814          

Query:  621 DLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-----DTDSSLATNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEA----AHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKK 2150
            +++     +L  Y +    F DK ++C+P     + IPQ E   RKD   ECI +IDP  A+D+DDAL  + +  GN+ VGVHIADVSYF+   +ALD  A  RA+S+YL  KVIPMLP +L E LCSLNP  D+L FS++  I P GEI+ E F +SVI    KLSY  A  +IN      +       +P +   +  +++L L  +A  +RK+R D GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  ++  F    P E    A LR+HP P+    +   + C + G + +     ++ + +N   ET+ + A     LT +    M +A Y C                + D    FHHY LNVPLYTHFTSPIRR+AD++VHR L+A +     CG  L    E     A +CN  + A++R+ +    ++ + ++ + G    + +++ +   +  V++   G+  R     L P  + + +Q  K+
Sbjct:  299 EIEPETEGILVEYGVDFSDFPDKVLQCLPQDLP-WTIPQEEFQKRKDLRNECIFTIDPATARDLDDALSCKPLPDGNFEVGVHIADVSYFVAEGSALDIMASERATSVYLVQKVIPMLPRLLCEELCSLNPMTDRLTFSVIWKITPQGEILDEWFGRSVICSCVKLSYDHAQNMINHPDKKIEQHELPPVSPQHTINEIHQAVLNLHLIAQNLRKQRFDDGALRLDQLKLTFTLDKES----------GLPQGCYIYQYRDSNKLVEEFMLLANMAVAHHIYRRF----PEE----ALLRRHPPPQTKMLNDLIEFCDQMGLQLDFSSSGTLHKSLNDQFETDEYSAARKEVLTNMCSRPMQMAVYFC-------------TGALKDETL-FHHYALNVPLYTHFTSPIRRFADVIVHRLLAASL----GCGPPLKMPKEVIQKQADHCNDRKTASKRVQELSAELFFSVFVKECGPLESEAMVMGVLNEAFDVIVLRFGVQKRIYCNSL-PLVNSHFQQVGKR 784          

Query:  408 RGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLA-----TNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKK 2150
            + CP+  +   K Y+     C+I++W                               F             +++     +L  Y +    FS + +EC+P     + IP  E   R+D   +CI +IDP  A+D+DDAL  + ++ GN+ VGVHIADVSYF+   + LD  A  RA+S+YL  KV+PMLP +L E LCSLNP  DKL FS++  + P+G+I+ E F +++IR   KLSY+ A ++I   T+   A      +P +  E+  +++L L  +A  +R++R   GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  +   F    P +    A LR+HP P+    S   + C + G   +     ++ + + Q    + +       LT +    M +A Y C+       DP Q           F HY LNVPLYTHFTSPIRR+AD++VHR L+A +       ++     + A +CN  R+A++R+ +  TS++ A  + + G    + +++ I   +  VL+   G+  R     LA   S + ++  KK
Sbjct:  283 KDCPQDFVARPKDYANTLFICRIVDWKEDC--------------------------NFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP-WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLRQQRFVDGALRLDQLKLAFTLDHE----------TGLPQGCHIYEYRESNKLVEEFMLLANMAVAHKIHRAF----PEQ----ALLRRHPPPQTRMLSDLVEFCDQMGLPVDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSG---LLQDPAQ-----------FRHYALNVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDMAPDTLQKQADHCNDRRMASKRVQELSTSLFFAVLVKESGPLESEAMVMGILKQAFDVLVLRYGVQKRIYCNALA-LRSHHFQKVGKK 813          

Query:  621 DLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDS-------SLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELA 2111
            +++     +L  Y +    FS + +EC+P S   + IP  E   R+D   +CI +IDP  A+D+DDAL  + ++ G + VGVHIADVSYF+   ++LD  A  RA+S+YL  KV+PMLP +L E LCSLNP  DKL FS++  + P+G+I+ E F +++IR   KLSY  A ++I   T+         ++     E+  +++L L  +A  +R++R   GAL +++  + FT + +             P G        SN L+EEFMLLAN A A  +F  F    P +    A LR+HP P+    S   + C + G   +     ++ + + +    + +       LT +    M +A Y C+       D EQ           F HY LNVPLYTHFTSPIRR+AD++VHR L+A +       +      + A +CN  R+A++R+ +    ++ A  + + G    + +++ +   +  VL+   G+  R     LA
Sbjct:  326 EIEPETEGILTEYGVDFSDFSSEVLECLPQSLP-WTIPPDEVGKRRDLRKDCIFTIDPSTARDLDDALACRRLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMTDKLTFSVIWKLTPEGKILEEWFGRTIIRSCTKLSYDHAQSMIENPTEKIPEEELPPISPEHSVEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLKLAFTLDHE----------TGLPQGCHIYEYRDSNKLVEEFMLLANMAVAHKIFRTF----PEQ----ALLRRHPPPQTKMLSDLVEFCDQMGLPMDVSSAGALNKSLTKTFGDDKYSLARKEVLTNMYSRPMQMALYFCSG---MLQDQEQ-----------FRHYALNVPLYTHFTSPIRRFADVIVHRLLAAALGYSEQPDVEPDTLQKQADHCNDRRMASKRVQELSIGLFFAVLVKESGPLESEAMVMGVLNQAFDVLVLRFGVQKRIYCNALA 799          

Query:  570 FQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEK-FTKSVIRPKFKLSYKQANALINGDTDSSLATNP----HYEKAVE-SLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGL-SFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDN----LTSVYMASYLNQVGWRL--VKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKKNTPVAVSLTYNSNKEDYSITMDKGFPRYVY 2240
            + ++P      K   + D+++  + LL    ++  PFSD+ + C+P   ++++I   E   R+D   E II+IDP+ A+D+DDA+  +A+  G Y VGVHIADV++F+KPD+ALD  A  RA+++YL  K IPMLPP+L E LCSLNPN ++LAFS+   ++ +G+ I ++ F K+VI+   +L+Y +A  +I G +       P    H  K VE S+L L +++  +RK R   GA+ IN   + F             D    PN  +      +N LIEEFMLLAN++ A+ +  NF ++        + LR+H SP++ + + +    K   F  ++    +    + +++ T   + + L   +   ++N AEY C  +     D              +HHY L+   YTHFTSPIRRY DI+VHR L   +K   S GI        A +CN  +  +  + ++      SVY+A Y  +   +   V+     I+GNS+ V ++  GI +R +L       S  V   A  ++ V ++L  +S K   +I +   F  Y+Y
Sbjct:  382 YSRYPMGVLGEKLGNITDVEAYTNALLLENGISSSPFSDEVLNCLPP--DDWIISHEEIKKRRDLRNELIITIDPETARDLDDAVSCRALDNGTYEVGVHIADVTHFVKPDSALDKEAASRATTVYLVQKAIPMLPPLLCERLCSLNPNVERLAFSVFWKLDSNGKEIGKRWFGKTVIKTCARLAYSEAQGVIEGKSWDDAVGKPIGGTHTPKDVETSILTLCEISRKLRKDRFAKGAVEINSTELKFQL-----------DEYGMPNKCEVYEQTDANHLIEEFMLLANRSVAEHISKNFSNN--------SLLRRHASPKEKQINEFCHFLKSMNFDFDASSSAAFNASMVRLRSTFNEELVELFENMAVRSLNRAEYFCTGDFGEKTD--------------WHHYALSFNHYTHFTSPIRRYPDIIVHRLLERSLKN-TSPGIDKKNCSLVAAHCNEKKEKSTTVQEDSQQLFLSVYIAEYCKKHDKKSMPVQAFATRISGNSIDVYISEYGISNRVDLSSDDRIKSFIV---APDDSSVKITLFDDSQK---TIALTDRFQVYLY 909          

Query:  678 FSDKDMECVP-ASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVS-----GGNYL-VGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALI-NGDTDSSLATNPHYEKA------VESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKAL---GLSFLTYINMNVAEYCCA-ENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRL-EAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHR 2090
            FSD+ +E +P  +AE + +P  E + R+DF ++ + +IDP  A+D+DDALH + +      G   L +GVHIADV++F+K  T LD  A  R +S YL   VIPMLP IL E LCSLNP  D+L+FS +  ++ + E+    F +SVIR + KL+Y+ A   I N + D +    P            E  L+L ++A V+R++R DSGAL I  P + F             D   +P G+    +  SN L+EEFMLLAN   AK +  NF           A LR HP P++       + C R GF  + +    +   + + Q            +S LT   M  A+Y C  E  LSF                +HH+ LNV  YTHFTSPIRRY D++VHRQL+A + G N     + + + E    CN +++A++  +D    +Y   +++Q G    + +++ +   S  VL+   G++ R
Sbjct:  307 FSDECLESLPITTAENWKVPDAEFEYRRDFRSDIVFTIDPKTARDLDDALHAKHIDDCDGKGTPGLEIGVHIADVTFFLKEGTELDKWASERGNSTYLSQTVIPMLPRILCEQLCSLNPGVDRLSFSTVFKMSYEAELYDVWFGRSVIRSRVKLAYEHAQDFIENPEKDFTCDELPDISDGNTPFEIKEKTLMLHRIAQVLRQKREDSGALRIELPRLKFAL-----------DEDKKPQGVSIYEIKDSNKLVEEFMLLANMEVAKKIAENFPEH--------ALLRNHPPPKEKMIKDVAEQCARIGFPLDGRTSGLLSTSLRKYQGKSRLDMCIRQVISSLTIKPMQQAKYFCTFEMPLSF----------------YHHFALNVDHYTHFTSPIRRYPDVIVHRQLAAAL-GYNERSERVPEEIQEICTRCNDTKLASKEASDESAMLYFGVFIHQTGPMKCQAVVLGVMDLSFDVLIVEYGVVKR 760          

Query:    3 CYVMKVPVIYFTXXXXXXXXXXXXXXXXXXXDKVDPKQAENIHIISLLPISEWLFREKFRVLNFNESKFSWYLKNSFPEKNSLIDKPLNSYLFVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKKNTPVAVSLTYNSNKEDYSITMDKGFPRYVYRKEDDEKPGVENVDWNKLLVKNHSKSRGKMQIDLVLSKEEEIEGDSTTQEMNCLSQDKREIRCADXXXXXXXXXXXXXAIYCKDNLLALSVELPFPPISSMLDEDSNRIS 2570
            CYVMKVP++  + S +               DKVDPKQAENIHIISLLPISEWLFREKFRVLNFNESKFSWYLKNSFPEKNSLIDKPLNSYLFVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLK+YKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECIISIDPDDAKDIDDALHIQAVSGGNYLVGVHIADVSYFIKPDTALD TALHRASSIYLKHKVIPMLPPILSEHLCSL PNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASR+VEQKAKKNTPVAVSLTYNSNKEDYSITMDKGFPRYVYRKEDDEKP VENVDWNKLLVKNHSKSRGKMQIDLVLSKEEEIEGDSTTQEMNCLSQDKREIR ADELFNLTLFEELNFAIYCKDNLLALSVELPFPPISSMLDEDSNRIS
Sbjct:   56 CYVMKVPILGISISIL---------------DKVDPKQAENIHIISLLPISEWLFREKFRVLNFNESKFSWYLKNSFPEKNSLIDKPLNSYLFVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKVYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECIISIDPDDAKDIDDALHIQAVSGGNYLVGVHIADVSYFIKPDTALDCTALHRASSIYLKHKVIPMLPPILSEHLCSLTPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRHVEQKAKKNTPVAVSLTYNSNKEDYSITMDKGFPRYVYRKEDDEKPRVENVDWNKLLVKNHSKSRGKMQIDLVLSKEEEIEGDSTTQEMNCLSQDKREIRYADELFNLTLFEELNFAIYCKDNLLALSVELPFPPISSMLDEDSNRIS 896          

Query:  618 KDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING---DTDSSLATNP-----HYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESK--------EFDSSNTNDSIPE-PNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNE---------------------SEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVN----QIQETEPHK------ALGLSFLTYINMNVAEYCCAENCL-------------SFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIK-GENSC----GISLSQ-------RLEA-AHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRY 2129
            ++++ A   +L  + + ++ F+D+ ++ +PAS  +FVIP +E   R+DF + C++S+DP  AKD+DDALH++ ++   Y VGVHIADVS+F++P TALD  A  R +S YL  +VIPMLPPILSEHLCSLNP  D+LAFS++  ++ +G I+   F +SVIR   +LSY+ A AL++    + DS  +  P       E    S+  LD LA  +RKRRVD+GAL+++K  + F    K             N +D  P  P G   K  GR+++LIEE+ML  NQA A+ LF   +  +  E                     S +G  LR+HP+P+  K          A    ++    ++   ++    +++E    +      +  LS+LTY+ M +A Y   E+ +             S  D   E    +   F  HH+GLNVPLYTHFTSPIRRYAD++VHRQL+ ++  G  SC    G + S+       RL   A  CN  R   RR  +    +++A+++   G    K +++N  G  + +L+ S G++   +L++  P AS +
Sbjct:  181 QEIEPATQEILLSHGIYEKDFTDEMVKELPASEADFVIPNYEYLRRRDFRSHCVVSVDPSTAKDLDDALHVKKIAKDVYEVGVHIADVSFFVRPLTALDREAADRTTSTYLVQRVIPMLPPILSEHLCSLNPGVDRLAFSVVFKVDRNGNILEVWFGRSVIRSCARLSYEDATALLDTPYEELDSLSSRIPTQDPFTLENVKRSITYLDMLAQQMRKRRVDNGALLLDKIELQFDLTPKTPEDIQNSSLKGGNKSDQTPGWPRGYTVKQRGRAHYLIEEWMLATNQAVARRLFYEAIKRKHEEILKFNEDVKEVKQETEKTKFRSSLGTILRRHPAPKASKMEELVRITTAAAISMDTSSAGAMRASLDAHIAELREKNVPQPDIECLSTALSYLTYMRMQMALYFNVEDVVDRAVRKVRRSGQASSTDVSHESWEASLLRFS-HHFGLNVPLYTHFTSPIRRYADLLVHRQLADLLGCGHWSCPKAPGTTTSRSPVCPPKRLTVQAAWCNRMRRETRRAQEESQQLFLAAWVKSNGSIQDKAVVLNFGGGKIQLLIPSCGLILTHQLQKFCPAASTW 757          

Query:  609 AAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-DTDS---------SLATNPH----YEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFD--------------SSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLS-----SRP-------NESEIGAFLRKHPSPEKIKKSRWYDSCKRAGF---RPESKDLNSIM-----EVVNQIQETEPHKAL--GLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFH---HYGLNVPLYTHFTSPIRRYADIVVHRQLSAI----------------------IKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELA----------PWASRYVEQKAKK---NTPVAVSLTYNSNKEDYS 2204
              + +L+ A   +L  Y L D+ F  + +E +P   E+F IP  E   R+DF + C++SIDP  AKDIDDALHI+ +    + VG+HIADVSYF+KP TALD  A  R +S+YL  +VIPMLP ILS HLCSL P  D+LAFS+++ I   GEI+   F +++IR + KLSY +A AL+   D DS          +   P      E   ++L  L+K+A  +RK+R+  GAL + K  + F   S  FD              +S+T D    P G   +  G S+ LIEE+ML ANQA A+ LF  F+      S+P        +   GAFLR+H  P K          + AG       SK L+  +     +++      E   A+   LS L Y+ M +A Y   ++ L+  +PE    I  + D  F    HYGL VPLYTHFTSPIRRYAD++VHRQLSAI                      +         LSQ    A  CN+ R+ +RR  +    +++ + L   G  L+ G +++   +S+ VLL+  GI+  C L++            P +S+  +  + +   NT   +S  +  N++ +S
Sbjct:  251 GGMDELELATKQILIEYGLEDKDFLPEHLEGLPKDPEDFRIPSTEYLKRRDFRSCCVLSIDPASAKDIDDALHIRPIDNDLFEVGIHIADVSYFVKPGTALDREAADRTTSVYLVQRVIPMLPAILSSHLCSLQPGADRLAFSVVMKIRTSGEIVDVWFGRTIIRSRTKLSYDEALALMETVDLDSHSEKVKQVYKVIPKPEAPFKLEDVRDALTNLNKIARNLRKQRLQQGALTLQKAKIEFDLPSSTFDPGPFDPIYPSNSAETSSTLDRTRWPRGYSVRSPGPSHQLIEEWMLAANQAVARRLFQAFVQHVSSCSKPTVIDQFGQDVWPGAFLRRHEEPSKKNLKELSALFETAGIDLGDGSSKALSQALYNHSRKLIEAGHSEEERTAIMDALSHLVYVRMKMATYFSLDD-LTLINPELLQSIPTNVDQVFEHTWHYGLCVPLYTHFTSPIRRYADLLVHRQLSAILHESEHQRDPVSQVGRIRKSRRLSESGRTNQPLSQLALQAQWCNIRRMLSRRAQEASQRLFLTACLRDCGPLLMDGTVLDFNASSIKVLLSEFGIIVSCPLKKFLRQVNWQLITDPQSSKRADSNSDRDGHNTRTHISTQWTVNQKHHS 869          

Query:  579 FPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-DTDS---------SLATNPH----YEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFD--------------SSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLS-----SRP-------NESEIGAFLRKHPSPEKIKKSRWYDSCKRAGF---RPESKDLNSIM-----EVVNQIQETEPHKAL--GLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFH---HYGLNVPLYTHFTSPIRRYADIVVHRQLSAI----------------------IKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELREL 2108
             P    + +   + +L+ A   +L  Y L D+ F  + +E +P   E+F IP  E   R+DF + C++SIDP  AKDIDDALHI+ +    + VG+HIADVSYF+KP TALD  A  R +S+YL  +VIPMLP ILS HLCSL P  D+LAFS+++ I   GEI+   F +++IR + KLSY +A AL+   D DS          +   P      E   ++L  L+K+A  +RK+R+  GAL + K  + F   S  FD              +S+T D    P G   +  G S+ LIEE+ML ANQA A+ LF  F+      S+P        +   GAFLR+H  P K          + AG       SK L+  +     +++      E   A+   LS L Y+ M +A Y   ++ L+  +PE    I  + D  F    HYGL VPLYTHFTSPIRRYAD++VHRQLSAI                      +         LSQ    A  CN+ R+ +RR  +    +++ + L   G  L+ G +++   +S+ VLL+  GI+  C L++ 
Sbjct:  357 LPYGVISEQLGGMDELELATKQILIEYGLEDKDFLPEHLEGLPKDPEDFRIPSTEYLKRRDFRSCCVLSIDPASAKDIDDALHIRPIDNDLFEVGIHIADVSYFVKPGTALDREAADRTTSVYLVQRVIPMLPAILSSHLCSLQPGADRLAFSVVMKIRTSGEIVDVWFGRTIIRSRTKLSYDEALALMETVDLDSHSEKVKQVYKVIPKPEAPFKLEDVRDALTNLNKIARNLRKQRLQQGALTLQKAKIEFDLPSSTFDPGPFDPIYPSNSAETSSTLDRTRWPRGYSVRSPGPSHQLIEEWMLAANQAVARRLFQAFVQHVSSCSKPTVIDQFGQDVWPGAFLRRHEEPSKKNLKELSALFETAGIDLGDGSSKALSQALYNHSRKLIEAGHSEEERTAIMDALSHLVYVRMKMATYFSLDD-LTLINPELLQSIPTNVDQVFEHTWHYGLCVPLYTHFTSPIRRYADLLVHRQLSAILHESEHQRDPVSQVGRIRKSRRLSESGRTNQPLSQLALQAQWCNIRRMLSRRAQEASQRLFLTACLRDCGPLLMDGTVLDFNASSIKVLLSEFGIIVSCPLKKF 940          

Query:  579 FPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-DTDSS---------LATNPH----YEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFD--------------SSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLS-----SRP-------NESEIGAFLRKHPSPEK--IKK-SRWYDSCKR---AGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFH---HYGLNVPLYTHFTSPIRRYADIVVHRQLSAI----------------------IKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELA----------PWASRYVEQKAKK---NTPVAVSLTYNSNKEDYS 2204
             P    + +   + +L+ A   +L  Y L D+ F  + +E +P   E+F IP  E   R+DF + C++SIDP  AKDIDDALH++ +    + VGVHIADVSYF+KP TALD  A  R +S+YL  +VIPMLP ILS HLCSL P  D+LAFS+++ I   GEI+   F +++IR + KLSY +A AL+   D DSS         +   P      E   ++L  L+K+A  +RK+R+  GAL + K  + F   S  FD              +S+T D    P G   +  G S+ LIEE+ML ANQA A+ LF  F+      S+P        +   GA LR+H  P K  +K+    YD  ++   AG   E +   +IM+               LS L Y+ M +A Y   ++ L+  +PE    +  + D  F    HYGL VPLYTHFTSPIRRYAD++VHRQLSAI                      +         LSQ    A  CN+ R+ +RR  +    +++ + L   G  L+ G +++   +S+ VLL+  GI+  C L++            P +S+  +  + +   NT   +S  +  N++ +S
Sbjct: 1370 LPYGVISEQLGGMDELELATKQILIEYGLEDKDFLPEHLEGLPKDPEDFRIPSTEYLKRRDFRSCCVLSIDPASAKDIDDALHVRPIDNDLFEVGVHIADVSYFVKPGTALDREAADRTTSVYLVQRVIPMLPAILSSHLCSLQPGADRLAFSVVMKIRTSGEIVDVWFGRTIIRSRTKLSYDEALALMETVDLDSSSEKVKQLYKVIPKPEAPFKLEDVRDALTNLNKIARNLRKQRLQQGALTLQKAKIEFDLPSSTFDPGPFDPTYPSNSTETSSTLDRTRWPRGYSVRSPGPSHQLIEEWMLAANQAVARRLFQAFVQHFSSCSKPTVIDQFGQDVWPGALLRRHEEPSKKNLKELQALYDHSRKLIEAGHSEEER--TAIMD--------------ALSHLVYVRMKMATYFSLDD-LTLTNPELLQSLPTNVDQLFEHTWHYGLCVPLYTHFTSPIRRYADLLVHRQLSAILHESEHQRDPVSQVGRIRKSRRLSESGRTNQPLSQLALQAQWCNIRRMLSRRAQEASQRLFLTACLRDCGPLLMDGTVLDFNASSIKVLLSEFGIIVSCPLKKFLRQVNWQLITDPQSSKGADSNSDRDSHNTRTQISTQWTVNQKHHS 1978          

Query:  414 CPEIHIETDKKYSADNQACKIIEWTNHSV-PKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKD----LKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVS-------------GGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALI-NGDTD-----SSLATNPHYEKAVE---SLLILD----------KLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKA 1640
            CP+  I     +       +I  W   S+ P G+LL    P                   DST    A  D    +    S L  I++  D    +   E V  +   F+    E   R DF   C+ +IDP  A+D+DDALHI+++S             G  Y VGVHIADVSYF++P++ +D  A  RA++IYL    +PMLP IL E LCSLN  EDK  FS++  ++  G I+   F +SVIR   KLSY+ A  LI N D D     +S+   PH   +     S++++D           LA   R+RR   G+L +++    F            +D    P G+   I   SN+L+EE+ML AN++ A+ L      +        AFLR+H  P   + S+  DS K  G       +N   E    IQ +  H+A
Sbjct:  316 CPQAFISDPSSFKHVRYVARITSWPESSLFPTGELLRSLSP-------------------DSTKLVEAETDRILVVAGFYSGLDSIHRFPDS-VEESAKEAVCRANSAFLA---ELRWRTDFRPLCVFTIDPSTARDLDDALHIRSLSDKEIDELDQDGCPGATYEVGVHIADVSYFVRPNSPVDMEAARRATTIYLVQLCVPMLPRILCEELCSLNVGEDKRTFSVVFKVDKYGNILRSSFGRSVIRSCAKLSYENAQLLIDNPDEDIKPDFASMIEPPHSLASTTQKLSIMLVDAQRVSHACRAALAMQRRQRRFSGGSLRLDQIKTAFVL----------DDDKQIPLGVAPAISKPSNWLVEEWMLAANESVAERLAKELPET--------AFLRRHAPPSLNQLSKAADSLKSVG-------INVNTETAGSIQASICHEA 713          

Query: 1620 ETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAII----KGENSC-------------GISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVI---VLLTSSG 2078
            E E    + +S LT   MN+AEY C        +  +E            HY LN+  YTHFTSPIRRYAD++VHRQL+AI+    +G+ +              G+S  Q    A  CN  ++  RR  +    ++   ++     RL    ++ +T N+ +    L ++SG
Sbjct:  773 EQEARMLVAVSLLTK-TMNLAEYFC------LGELPKECTT--------EHYALNMEFYTHFTSPIRRYADVIVHRQLAAILAREARGDGNAELADWYAQTVCTPGLSSKQLQTQAEVCNSKKLCARRAGEESAELFYVLFVKSAALRLYPSSIL-VTANTNVDREALTSASG 929          

Query:  300 LRPTGRIVSTITDLNSITFIGSL-----KPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALG-----LSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAA--HNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGI 2081
            L+PTGR+V  I   N   F G L     K    HL F P +R  P I IET        QA  ++         G+ +  A+     +S        ++PN           D  +    LL  + +  +PFS   +  +P     + I + +   R D    C+ S+DP    DIDDALH + +  GN  VGVHIADVS+FI+P  ALD  A +R +++YL  K I M+P +LS +LCSL  N ++LAFS +  +N + EI++ +F KS+I  K  L+Y +A   I+   D+ +      +    SL  L+KLA +++ +R++ GAL ++ P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ +++ F       SE  A LRKHPSP        YD   +A    +S+DL+           T+  KAL       +   +   N      A  C+      Q V   +  D  FHHYGL  P+YTHFTSPIRRY+DI+VHR L+  I  +++    + +  +A+  +N N      +       + +   +    G    +G ++ +  N++I+L+   G+
Sbjct:  315 LKPTGRVVGIIKR-NWRPFCGMLNQSQIKEATRHL-FTPADRRIPRIRIET-------RQASTLV---------GQRIIVAIDGWPRNS--------RYPNGHFVRNLGGAGDKDTETEVLLLEHDVPHQPFSQTVLSFLPKMP--WGITEEDLKVRTDLRHLCVCSVDPPGCTDIDDALHCRDLENGNLEVGVHIADVSHFIRPGNALDQEAANRGTTVYLCGKRIDMVPELLSSNLCSLRSNVERLAFSCIWEMNHNAEILNTRFCKSIINSKASLTYAEAQMRID---DAGMN-----DDITTSLRGLNKLAKILKAQRIEKGALTLSSPEVRFHMDSETHD----------PIDLQTKELKETNSMVEEFMLLANISVAQKIYDEF-------SEC-ALLRKHPSPPPSN----YDILIKAA---KSRDLDI---------HTDSAKALADSLNEATLEDFPYFNTLLRILATRCMM-----QAVYFCSGMDSDFHHYGLASPIYTHFTSPIRRYSDIIVHRLLAVAISADSTYPDLMDKHKQASLCNNLNYRHKMAQYAQRASVAFHTQLFFKNRGILNEEGFILFVRKNAIIILIPKFGL 845          

Query:  519 FEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSA------ISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-----DTDSSLATNPHYEKAV--ESLLILDKLATVIRKRRVDSGALIINKPTVN 1292
            F + P  Y ++L F  +   +P  ++  +   +K L  A         +L  Y +    F +  + C+P +   + IP  E   R+D   ECI +IDP  A+D+DDAL  + +S GN+ VGVHIADVSYF++  TALDS A  RA+S+YL  KVIPMLP +L E LCSLNP  D+L FS++  ++P+G+I+SE F +SVIR   KLSY  A ++I        ++     +P +   +  ES+L L  LA  +R +R   GAL +++ T N
Sbjct:  323 FPSRPADYANTL-FICRITHWPYDNTFAEGRLMKSLGQAGEIEPETEAILTEYDVDFSEFEEAALACLPQNLP-WSIPPEELAKRRDLRKECIFTIDPATARDLDDALSCRQLSDGNFEVGVHIADVSYFVEEGTALDSVASRRATSVYLVQKVIPMLPRLLCEELCSLNPQTDRLTFSVIWTLSPEGKILSEWFGRSVIRSCIKLSYDHAQSMIQSPDKHFSSEELPPCSPDHPVQLIQESVLHLHSLAQHLRSQRFQGGALRLDQVTQN 591          

Query: 1647 LSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAH----NCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHR 2090
            L+ L    M +A Y CA              ++ D    F HY LNVPLYTHFTSPIRRY DI+VHR L+A +K    CG  LS   E  H    +CN  + A++R+ +    ++ + ++ + G    + +++ +   S  VL+   G+  R
Sbjct:  636 LTHLCSRPMQMAVYFCA-------------GVLQDEKL-FRHYALNVPLYTHFTSPIRRYPDILVHRLLAASLK----CGPRLSLSDEEVHKLASHCNDKKTASKRVQEMSAELFFSVFVRECGPLDSEAMVMGMLDKSFDVLVLQYGVQKR 769          

Query:  450 SADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFH----DKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEE--FVIPQHERDNRKDFT-AECXXXXXXXXXXXXXXALHIQAVSGGNYL-VGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDG-EIISEKFTKSVIRPKFKLSYKQANALINGDTD-----SSLATNPHYEKAVE---SLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGI-----SLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQ----VGWRLVK-GILINITGNSVIVLLTSSGI 2081
            S ++Q    + W ++ +PK ++  +    + +H +I      D    +PN  +        +L++ I  +L    +    FS+  +  +P ++ +  + +   E  +R+D      + SIDP   +D+DD L +Q + GG  L +GVHIADV++F+K  +  D  A  RA++ YL  +   MLP +LS  LCSL    D+ A S++  ++ +  E+    + +++IR  ++L Y+ A +L+NG+       + L ++   +K  E   +L  L ++A  +R +R   GAL +    V    +    +  N    +P       K     +  + E M+ AN   A+ +  +F    P++    A LR HP P +   ++  D  K  GF  +++   ++ + ++       H    L  L    M V       N L F+         + P+  ++HYGL +  YTHFTSPIRRYADI+VHR L A I+ E   G+     S  +  E AH  N    A +        ++   Y          R V   ++  I  N ++V +   G+
Sbjct:  353 SRNSQKILAVPW-DYRIPKIRISTQQAEALQDHRVIVRVDSWDSTSLYPNGHTVRVLGKAGELETEIQTILIENSIHVPAFSEAQLREMPVNSADQPWQMDGAEVSSRRDLRDTHLVFSIDPLGCEDVDDTLSVQTLPGGKRLELGVHIADVTHFVKEGSLTDLEARSRATTYYLADRRYDMLPTVLSADLCSLLGGVDRYAMSVLWELDAESLEVCKVWYGRTLIRSSYQLHYELAQSLLNGEEAEVPELAQLESSEQGQKLAELLQALETLTRMARHLRAQRDKGGALELEGVEVRAQLD----EDKNIAALVP-------KQPLEVHETVAECMIYANHWVARKIQESF----PHQ----ALLRHHPPPRQEFFNQLIDCAKTRGFTIDTRSNKTLADSLD-------HAVDPLDPLVNRLMRVMATQAMSNALYFSTG-------SCPEEQYYHYGLALDRYTHFTSPIRRYADIIVHRLLMAAIQSEKQEGLHKTLASNKELEELAHQINNKNRAAQHAQKQSVELFQCLYFRDKDPLTDERCVADAVIYTIRANGMLVFIPRYGL 889          

Query:  450 SADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFH----DKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEE--FVIPQHERDNRKDFT-AECXXXXXXXXXXXXXXALHIQAVSGGNYL-VGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDG-EIISEKFTKSVIRPKFKLSYKQANALINGDTD-----SSLATNPHYEKAVE---SLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGI-----SLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQ----VGWRLVK-GILINITGNSVIVLLTSSGI 2081
            S ++Q    + W ++ +PK ++  +    + +H +I      D    +PN  +        +L++ I  +L    +    FS+  +  +P ++ +  + +   E  +R+D      + SIDP   +D+DD L +Q + GG  L +GVHIADV++F+K  +  D  A  RA++ YL  +   MLP +LS  LCSL    D+ A S++  ++ +  E+    + +++IR  ++L Y+ A +L+NG+       + L ++   +K  E   +L  L ++A  +R +R   GAL +    V    +    +  N    +P       K     +  + E M+ AN   A+ +  +F    P++    A LR HP P +   ++  D  K  GF  +++   ++ + ++       H    L  L    M V       N L F+         + P+  ++HYGL +  YTHFTSPIRRYADI+VHR L A I+ E   G+     S  +  E AH  N    A +        ++   Y          R V   ++  I  N ++V +   G+
Sbjct:  354 SRNSQKILAVPW-DYRIPKIRISTQQAEALQDHRVIVRVDSWDSTSLYPNGHTVRVLGKAGELETEIQTILIENSIHVPAFSEAQLREMPVNSADQPWQMDGAEVSSRRDLRDTHLVFSIDPLGCEDVDDTLSVQTLPGGKRLELGVHIADVTHFVKEGSLTDLEARSRATTYYLADRRYDMLPTVLSADLCSLLGGVDRYAMSVLWELDAESLEVCKVWYGRTLIRSSYQLHYELAQSLLNGEEAEVPELAQLESSEQGQKLAELLQALETLTRMARHLRAQRDKGGALELEGVEVRAQLD----EDKNIAALVP-------KQPLEVHETVAECMIYANHWVARKIQESF----PHQ----ALLRHHPPPRQEFFNQLIDCAKTRGFTIDTRSNKTLADSLD-------HAVDPLDPLVNRLMRVMATQAMSNALYFSTG-------SCPEEQYYHYGLALDRYTHFTSPIRRYADIIVHRLLMAAIQSEKQEGLHKTLASNKELEELAHQINNKNRAAQHAQKQSVELFQCLYFRDKDPLTDERCVADAVIYTIRANGMLVFIPRYGL 890          

Query: 1116 LSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQ-ETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENS 1880
            L+Y +A   I+   D+S+      +   ESL  L+KLA +++ +R+   AL ++ P V F       DS   N     P  LQ K L  +N ++EEFMLL N +  + +++ F  S                     KSR  D       R +S    ++ + +N+   E  P+    L  L    M  A Y C+                   D  FHHYGL  P++THFTSPIRRY+DI+VHR L+  I  +++
Sbjct:   50 LTYAEAQMRID---DASMN-----DDITESLQGLNKLAKILKAQRIKKRALTLSSPEVRF-----HMDSETHN-----PIDLQTKELKETNSMVEEFMLLVNISVTQKIYDEFSES--------------------AKSRDLD------IRTDSA--KALADSLNEATLEDFPYFNTLLRILATRCMMQAVYFCS-----------------GMDSDFHHYGLASPIFTHFTSPIRRYSDIIVHRLLAVAINADST 242          

Query:  450 SADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFH----DKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEE--FVIPQHERDNRKDF-TAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDG-EIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYE------------KAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLF--NNFLSSRPNESEIG-AFLRKHPSP-----EKIKKSRWYDSCKRA-GFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENS 1880
            SA +Q   ++ W +  VPK ++       + ++ ++      +   Q+PN           +L++ ++ LL    ++  PFS+  +  +P  + E  + +   E   R D  ++  I S+DP   +D+DDAL ++ V+GGN  +GVHIADV++F++P +  D  A  RA++ YL  +   MLP +LS +LCSL    D+ A S+   ++ D  E+    + ++VIR  +KLSY+ A AL++G   +   T P  +            + V +L  L  +A  +R RR + G L +    V           S + DSI +              L+ +  L  ++  A+ +   N++++ R  ++  G A LR HP P     E++K      +C  A GF  ++    ++ E ++     +P+  L    L  + ++        N L F+         + P    +HYGL +  YTHFTSPIRRYAD++VHRQL A+++ + +
Sbjct:  359 SAKSQKVLVVPW-DFRVPKIRISTNQSQALQDYRVVVRIDSWEATSQYPNGHFVRVLGRAGELETEVAALLVENAISVLPFSEAQLREMPVDSPETPWRMDGEEVARRCDLRSSHLIFSVDPPGCEDVDDALSVKTVAGGNLELGVHIADVTHFLRPHSHTDLEARVRATTYYLADRRFDMLPSVLSGNLCSLLGGVDRYAVSVRWELDGDTYEVKRVWYGRTVIRSSYKLSYETAQALLDGGAAAQGVTIPELDAFDDGTRQERLRELVWALGRLTDVARAMRARRTEEGGLELESVEVRVQM-------SESRDSIAD--------------LVPQQPLEVHETVAECMIAANHWVARRVAQALPGRALLRHHPPPRHEFFEELK------ACAAAMGFHIDTSSNKALAESLDNA--VDPNDPLINKMLRSMAVH-----AMSNALYFSTG-------SLPADQHYHYGLALDHYTHFTSPIRRYADVMVHRQLLAVLEAKGA 822          

Query:  645 LLKIYKLTDEPFSDKDMECVPA--SAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEK---FTKSV--IRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQ--IQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRY 1826
            LL  + +  +PFS   + C+P   SA +    Q ++  R+D  A  I S+DP    DIDDALH + +  GN  VGVHIADVSYFI+P  ALD  A  R +++YL  KV      +L+     L P +  L+F         G  +  +   FT+ V  + P+  L+Y +A  ++    D +   +P       SL  L+ LA ++++RR+ SGAL +  P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ +   F           A LR+HP+P          + K      +     ++ E +++  +    P+    L  L    M  A Y C+                 DPD   HHYGL   +YTHFTSPIRRY
Sbjct:   22 LLLEHDVPHQPFSQAVLACLPLPRSASQ----QRDQAGREDLRALSICSVDPPGCTDIDDALHCKPLDNGNTEVGVHIADVSYFIRPGNALDKEASLRGTTVYLCEKVRCGF--LLATISSVLRPADFILSFLTAWAWIRRGHCVIARTPWFTRGVFIVSPQASLTYAEAQLMM----DDAGRKDP----VTSSLRGLNSLAKILKQRRIQSGALTLASPEVRFHMDSETHD----------PIDLQTKELKETNSMVEEFMLLANISVAERIVGEFPEC--------ALLRRHPAPPPSNYDILVKAAKSKNIEIQVDSAKALAESLDRAAVPGAPPYLNTLLRILATRCMMQAIYFCSS---------------MDPD--THHYGLATAIYTHFTSPIRRY 375          

Query:  645 LLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPP---ILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEK---FTKSV--IRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQ--IQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGI 2081
            LL  + +  +PFS   + C+P      +  + ++  R+D  A  I S+DP    DIDDALH + +  GN  VGVHIADVSYFI+P  ALD  A  R +++YL  K I        ILS  L +   N D L  +   +    G  +  +   FT+ V  + P+  L+Y +A  ++    D +   +P       SL  L+ LA ++++RR+ +GALI+  P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ +   F           A LR+HP+P          + K      +     ++ E +++  +    P+    L  L    M  A Y C+                 +PD   HHYGL   +YTHFTSPIRRY   +++    +  + +     +L+ R + A     S +A           +   +    G    +G ++ +  N+V+VL+   G+
Sbjct:  143 LLLEHNVPHQPFSQAVLACLPPPTFS-ITAEKDQAGREDLRALSICSVDPPGCTDIDDALHCKPLDNGNTEVGVHIADVSYFIRPGNALDEEASLRGTTVYLCEKNINCFTTRHFILS-FLTTSRMNNDNLILAWAWIRR--GHCVIARTPWFTRGVFIVSPQASLTYAEAQLMM----DDAGRKDP----VTSSLCGLNSLAKILKQRRIQNGALILASPEVRFHMDSETHD----------PIDLQTKELKETNSMVEEFMLLANISVAERIVGEFPEC--------ALLRRHPAPPPSNYDILVKAVKSKNIEIQVDSAKALAESLDRAAVPGAPPYLNTLLRILATRCMMQAIYFCSG---------------MEPD--THHYGLATAIYTHFTSPIRRYIFFLLNFSKRSYKQKQQQLCNNLNYRHKMAQYAQCSSVA----------FHTPLFFKSKGVVSEEGFVLFVRKNAVLVLIPKYGL 574          

Query:  621 DLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIM--LLINPDGEIISEK--FTKSV--IRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLS---FLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGI 2081
            D ++    LL  + +  +PFS   + C+P      +  + ++  R+D  A  I S+DP    DIDDALH + +  GN  VGVHIADVSYFI+P  ALD  A  R +++YL  KV      +L+     L P +  L+F  +    I     +I+    FT+ V  + P+  L+Y +A  ++    D +   +P       SL  L+ LA ++++RR+ +GAL +  P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ + + F           A LR+HP+P        YD   +A    +SK++   ++    + E+    A+  S     T   M    +C                   +PD   HHYGL   +YTHFTSPIRR+   +    LS   K +  C  +L+ R + A     S +A           +   +    G    +G ++    N V+VL+   G+
Sbjct:  185 DKETETEVLLLEHDVPHQPFSQAVLACLPPPTFS-ITAEKDQAGREDLRALSICSVDPPGCTDIDDALHCKPLDNGNTEVGVHIADVSYFIRPGNALDEEASLRGTTVYLCEKVRCGF--LLATISSVLQPADFILSFLTLAWAWIRHGHCVIARTPWFTRGVFIVSPQASLTYTEAQLMM----DDAGRKDP----VTSSLRGLNSLAKILKQRRIQNGALTLASPEVRFHMDSETHD----------PIDLQTKELKETNSMVEEFMLLANISVAERIVDEFPEC--------ALLRRHPAPPPSN----YDILVKAA---KSKNIEIQVDSAKALAESLDRAAVPGSACILATRCVMQAIYFCSG----------------MEPD--THHYGLATAIYTHFTSPIRRHTREI---DLSFFYKQQQLCN-NLNYRHKMAQYAQRSSVA----------FHTQLFFKSKGVVSEEGFVLFARKNPVVVLIPKYGL 612          

Query:  621 DLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLL--INPDGEIISEK--FTKSV--IRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGI 2081
            D ++    LL  + +  +PFS   + C+P      +  + ++  R+D  A  I S+DP    DIDDALH + +  GN  VGVHIADVSYFI+P  ALD  A  R +++YL  KV      +L+     L P +  L+F  +    I     +I+    FT+ V  + P+  L+Y +A  ++    D +   +P       SL  L+ LA ++++RR+ +GAL +  P V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ + + F           A LR+HP+P          + K      +     ++ E +++        A  L+  T   M    +C                   +PD   HHYGL   +YTHFTSPIRR+   +    LS   K +  C  +L+ R + A     S +A           +   +    G    +G ++    N V+VL+   G+
Sbjct:  208 DKETETEVLLLEHDVPHQPFSQAVLACLPPPTFS-ITAEKDQAGREDLRALSICSVDPPGCTDIDDALHCKPLDNGNTEVGVHIADVSYFIRPGNALDEEASLRGTTVYLCEKVRCGF--LLATISSVLQPADFILSFLTLAWAWIRHGHCVIARTPWFTRGVFIVSPQASLTYTEAQLMM----DDAGRKDP----VTSSLRGLNSLAKILKQRRIQNGALTLASPEVRFHMDSETHD----------PIDLQTKELKETNSMVEEFMLLANISVAERIVDEFPEC--------ALLRRHPAPPPSNYDILVKAAKSKNIEIQVDSAKALAESLDRAAVPGDRSACILA--TRCVMQAIYFCSG----------------MEPDT--HHYGLATAIYTHFTSPIRRHTREI---DLSFFYKQQQLCN-NLNYRHKMAQYAQRSSVA----------FHTQLFFKSKGVVSEEGFVLFARKNPVVVLIPKYGL 637          

Query:  573 QQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERD-----------NRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIK---KSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETE-PHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTS-VYMASYLNQV---GWRLVKGILINITGNSVIVLLTSSGI 2081
             ++P          ++  ++    LL  + +   PFS K +EC+PA   ++  P    D            RKD   + I SIDP    DIDDALH + +  GN+ VGVHIADV++F+KP TALD+    R +S+YL  K I MLP +L   LCSL P  D+ AFS++  ++    I++  F KSVIR +   SY+QA   I+  T      N      + +LL   KL+  ++++R+++GAL +  P V    +S+  D          PN ++ K L  +N L+EEFMLLAN + A+ +++ F  +        A LR+H +P        +   ++ K      ES    ++ + +++  + E P+    +  ++   M  A+Y  +    S+ D              F HYGL V +YTHFTSPIRRY D+V HRQL+  I  E    +SL+ R +   +     I  +  N        +  Y+ QV         G +I +  N ++VL+   G+
Sbjct:  460 HKYPLGHFVRDLGTIESAQAETEALLLEHDVEYRPFSKKVLECLPAEGHDWKAPTKLDDPEAVSKDPLLTKRKDLRDKLICSIDPPGCVDIDDALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARGTSVYLVDKRIDMLPMLLGTDLCSLKPYVDRFAFSVIWELDDSANIVNVNFMKSVIRSREAFSYEQAQLRIDDKT-----QNDELTMGMRALL---KLSVKLKQKRLEAGALNLASPEVKVHMDSETSD----------PNEVEIKKLLATNSLVEEFMLLANISVARKIYDAFPQT--------AMLRRHAAPPSTNFEILNEMLNTRKNMSISLESS--KALADSLDRCVDPEDPYFNTLVRIMSTRCMMAAQYFYS-GAYSYPD--------------FRHYGLAVDIYTHFTSPIRRYCDVVAHRQLAGAIGYE---PLSLTHRDKNKMDMICRNINRKHRNAQFAGRASIEYYVGQVMRNNESTETGYVIKVFNNGIVVLVPKFGV 935          

Query:  819 ALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDG-EIISEKFTKSVIRPKFKLSYKQAN-ALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIG--AFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAII 1865
            ALH++    G   +G H+ DV+  I+  +++D  A  R+S++++  K++ +LP   ++ L SL P ++    S++  ++     I S    +S I P   LS +Q +  L  G   S L+T     ++  +  I D  AT++              PT++   ES + +    + +I +      + LG    +I E     N   A+ ++          +++G  A LR+   P   K + +    +  G+  ++   + +++ V +I++ +    +G+  L +  M  A Y  A       DP+Q           + HY LN+P+YTHFT+P+RRYAD VVHRQL A+I
Sbjct:  713 ALHVRNNGNGTLELGCHVVDVTSHIEEGSSVDRRARKRSSAVFMPQKLVNLLPQSFNDEL-SLAPGKESATLSVVYTLDSSTLRIKSTWVGESTISPSNILSLEQLDEKLSTGSPTSYLSTVQEIARSFYARRINDPEATLL--------------PTLSL-LESLDDEKVKVDLNILD------RTLGF--VVINEIKRKVNSTVAEKIY----------TKLGDLALLRRQMQPIATKMASFRKKIQNFGYNFDTNTADELIKGVLKIKDDDVR--VGIEILLFKTMPRARYFIAGKV----DPDQ-----------YGHYALNLPIYTHFTAPMRRYADHVVHRQLKAVI 1014          

Query:  579 FPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGD----TDSSL---ATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKKNTPVAVSLTYNSNKE 2195
            F   + +       +++     +   Y +   PF D+ ++C+P     + IP+ E  +R+DF  EC+ +IDP  A+D+DDALH + +S G   VGVHIADVS+F+K  T LD  A  RA+S Y+   V+PMLP  L E LCSLNP+ED+L FS++ ++   GEI S+   + +IR + K++Y+ A  +I+      +DS L   A      + V+ + +L K+A  +R+ R ++GAL +++  + F  + +             P G        SN LIEEFMLLAN   A  ++  F           A LR+HP P + +     + C+  G +  +    SI   + Q         + L  LT   M  A Y CA         E+E          + HY L+VPLYTHFTSPIRRYAD++VHR L+A ++               A +CN  ++A +   +  + ++ A ++ + G     G ++ I   S  V + + G+  R   +   P   RYV    K+     ++L + +  E
Sbjct:  231 FATGEISRSLGEAGEIEPETQGIFFEYGIDPGPFPDEALDCLPKETP-WSIPETEFAHRRDFRDECVFTIDPLTARDLDDALHCKRLSDGLIEVGVHIADVSFFVKTGTPLDDIAQERATSTYMVQTVVPMLPRRLCEELCSLNPDEDRLTFSVVWIMTDQGEIKSDWKGRGIIRSRVKMAYEHAQEMIDKPNKKWSDSELPPIAEGTDVSEIVKRVNLLAKIARQLRRNRFENGALRLDQVKLQFDLDKE----------TGMPIGYHVYQQRESNKLIEEFMLLANMTVAHHIYKAFPDM--------ALLRRHPKPHEKQMEDLLELCRNLGIKYNANSSKSIQVSLAQFPSGSAQHEI-LVQLTMKPMKNALYFCAGTV------EEE---------EYGHYALSVPLYTHFTSPIRRYADVIVHRLLAASLELAEPLDKDAVDVDSIAGHCNDCKLAAKTAGELSSELFFAIFVRECGPLEEDGYVLGIMDMSFDVFVPALGVTKRIYCK-FCPGVKRYVPYDRKEQVQPEITLVWATGTE 740          

Query:  429 IETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFH-DKFQ---QFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASA--EEFVIPQHERDNRKDF-TAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING---------------DTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQE-TEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLE 1910
            +  D++ SA      ++ W ++ +PK ++    +  + +   +   D ++    +P+         + DL++ ++ L+  + L+  PF+D  ++ +P+ +  E +VI + E   R+D   +  + SIDP   +D+DD L I+ +  G   +GVHIADV++F+ P +  D+ A  R++S+YL  +   MLP ILS +LCSL    D+LA S+M ++  + ++I   + +++IR  +KL Y+ A A+ +G                 DSS A N   +    S+L L  +A   + RR   GA+ ++ P V      K+    +  D I +  GL+       +  IEE M+LAN   AK L   F +         + LR+HP P +          K  GF  ++     + E +++ ++  +P     L  L    M+ A Y  +   +S ++              F HYGL +  YTHFTSPIRRYAD++VHR L A +  ++   +  ++ LE
Sbjct:  354 VSQDQRRSAGKVV--VVPW-DYRIPKIRISTRQVEALRDQRYVIRIDSWEVDSMYPSGHFVRALGLIGDLETEVATLMVEHTLSAPPFTDGQLKELPSDSPTEPWVISEEEVCRRRDLRKSHLVFSIDPKGCEDVDDTLSIRQLKDGRLELGVHIADVTHFVHPGSLTDAEARSRSTSVYLADRRYDMLPEILSANLCSLISGVDRLAMSVMWVLGSNYDVIKTWYGRTIIRSSYKLFYEVAQAIADGVVPNEDLLKEIPELQGLDSS-AANKGIQDIRWSVLKLMDIARYYKARRQTQGAVELDNPEVKVLLNEKK----DILDLI-DKQGLEI------HETIEECMILANHWVAKRLVQTFPTC--------SLLRRHPLPRQQYFENLMQCAKAKGFTIKTSSNKLLAESLDKCEDPDDPTFNKLLRILAVQAMSSALY-FSTGSVSVDE--------------FVHYGLALDRYTHFTSPIRRYADVIVHRLLMAALGSDDQSQVLNNEELE 832          

Query:  681 SDKDMECVPASA----EEFVIPQHERDNRKDF----TAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHK---VIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIIS-EKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEP-------------HKALGLSFLTYINMNVAEY-----CCAENCLSFNDPEQEVKIINDPDFP--FHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGE 1874
            +D  ++ VPA      E++ IP  E  +R  F    T +C  +++ DD      AL ++A + G   VGVH+ADVSYFI  D++ D  A  + +S Y        + MLP  L   LCSL P + +LA S++   N  G  +   +  +S++  K+ L++ Q +A++NG       +   Y      + +L  ++  +   R   G L      V  T  SK                        S+ ++E+ M+ AN A A+ L  +        ++    LR    P+      W  +C+RAG  PES  L       N   +  P               A+    +T +  ++AE+         +C   +  E+   +++    P  + H+ L +  YTHFTSP+RRY DIVV R L A++  E
Sbjct: 1559 ADNGLQLVPARMGGFNEDWTIPDTEWGSRLHFSEALTIDCGKTMELDD------ALSVKAGANGVVSVGVHVADVSYFISKDSSFDQAAFAQGTSAYPTDGSGIAVNMLPEQL-RRLCSLLPGKHRLAISVIFTFNTQGRSLRLPEVRRSIVSSKYSLTFDQCDAVLNGQASELPESVKRY------IHVLGSMSRKLYSLRTRQGCLAGLLDAVRATTFSK------------------------SSQIVEQLMIFANTAVAEKLLKS------GRTKDLTPLRTQSPPKSHILQSWSLACERAGILPESS-LTLRRVASNPSSQNTPSTVSVKVDLLGKISTAINAKDITLLTESLAEFDTDGRALEAHCRLSSLQERSQYVLSSKVGPAGYGHFTLGLDAYTHFTSPLRRYFDIVVQRMLVAVMLDE 1944          

Query:  300 LRPTGRIVSTITDLNSITFIGSLK--PMNTHLMFWPYNRGCPEIHIETD----------KKYSADNQACKIIEWT-NHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-----DTDSSLATNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLE-AAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKKNTPVAVSLTYNSN 2189
            L+ T ++V  +   +S    GSLK  P     +F P +   P I++             + Y+     C+I +WT +++  +G+L                           T  QA   +++     +L  + +    F+ + +EC+P     + IP  E + RKD   +CI +IDP  A+D+DDAL  + +  GN+ VGVHIADVSYF+K DTALD  A  RA+S+YL  +V+PMLP +L E LCSLNP+ D+L FS++  + P+G+I+SE F +SVIR   KLSY  A ++I         +     NP +  ++  E++L L  +A  +R++R+ +G L +++  ++F          N N     PN         SN L+EEFMLLAN A+A  +   F    P+     A LR+HP P+        + C + G   +     ++ E +N +   + + A   + LT++    M +A Y C+              ++ +    F HY LN+PLYTHFTSPIRRYADI+VHR L++         +S+SQ +E  A +CN  ++  +R+ +  + ++    + + G      +++ +   S  VL+   G+  R   +      S    Q  KK+    V L  N +
Sbjct:  169 LQKTAKVVYIVEKKHSRAVTGSLKFFPDKPFALFSPVDHRVPRINVPLSDCPEDFNIRPEVYANTLFICRITDWTADNAFAQGRLA-------------------------KTLGQAG--EIEPETEGILTEHSVDFSDFTPEVLECLP-QPRPWCIPPEELEKRKDLRRDCIFTIDPATARDLDDALSCKLLPDGNFEVGVHIADVSYFVKEDTALDEAASQRATSVYLVQQVVPMLPRLLCEELCSLNPDFDRLTFSVIWKLTPEGKILSEWFGRSVIRSCAKLSYDHAQSMIEAPEKLFSPNELQLDNPEHPIDEIHEAVLRLHSIAQNLRRQRISTGTLKLDQVKLSF----------NINKESMMPNSCSVYEYKDSNRLVEEFMLLANIATAHHIHRKF----PD----LALLRRHPPPKTKMMEELKEMCSQLGIDIDLSSPGALQESLNNLTGKDEYSAARKAVLTHLCSRPMQMALYFCS-------------GMLKNEQL-FKHYALNIPLYTHFTSPIRRYADIIVHRLLAS--------SLSMSQEVEKQALHCNNKKMLAKRVWELSSELFFGLLVRESGPLDSAAMVMRVLDQSFDVLVIKYGVQKRVYCKATKGLQSFRYHQVGKKSELTLVWLPENQD 754          

Query:  300 LRPTGRIVSTITDLNSITFIGSLK--PMNTHLMFWPYNRGCPEIHIETD----------KKYSADNQACKIIEWT-NHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING-----DTDSSLATNPHY--EKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYI---NMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKKNTPVAVSLTYNSN 2189
            L+ T ++V  +   +S    GSLK  P     +F P +   P I++             + Y+     C+I +WT +++  +G+L                           T  QA   +++     +L  + +    F+ + +EC+P     + IP  E + RKD   +CI +IDP  A+D+DDAL  + +  GN+ VGVHIADVSYF+K DTALD  A  RA+S+YL  +V+PMLP +L E LCSLNP+ D+L FS++  + P+G+I+SE F +SVIR   KLSY  A ++I         +     NP +  ++  E++L L  +A  +R++R+ +G L +++  ++F          N N     PN         SN L+EEFMLLAN A+A  +   F           A LR+HP P+        + C + G   +     ++ E +N +   + + A   + LT++    M +A Y C+              ++ +    F HY LN+PLYTHFTSPIRRYADI+VHR L++ +K      +S  +  + A +CN  ++  +R+ +  + ++    + + G      +++ +   S  VL+   G+  R   +      S    Q  KK+    V L  N +
Sbjct:  403 LQKTAKVVYIVEKKHSRAVTGSLKFFPDKPFALFSPVDHRVPRINVPLSDCPEDFNIRPEVYANTLFICRITDWTADNAFAQGRLA-------------------------KTLGQAG--EIEPETEGILTEHSVDFSDFTPEVLECLP-QPRPWCIPPEELEKRKDLRRDCIFTIDPATARDLDDALSCKLLPDGNFEVGVHIADVSYFVKEDTALDEAASQRATSVYLVQQVVPMLPRLLCEELCSLNPDFDRLTFSVIWKLTPEGKILSEWFGRSVIRSCAKLSYDHAQSMIEAPEKLFSPNELQLDNPEHPIDEIHEAVLRLHSIAQNLRRQRISTGTLKLDQVKLSF----------NINKESMMPNSCSVYEYKDSNRLVEEFMLLANIATAHHIHRKFPDL--------ALLRRHPPPKTKMMEELKEMCSQLGIDIDLSSPGALQESLNNLTGKDEYSAARKAVLTHLCSRPMQMALYFCS-------------GMLKNEQL-FKHYALNIPLYTHFTSPIRRYADIIVHRLLASSLKCGPHLQLSAQEVEKQALHCNNKKMLAKRVWELSSELFFGLLVRESGPLDSAAMVMRVLDQSFDVLVIKYGVQKRVYCKATKGLQSFRYHQVGKKSELTLVWLPENQD 995          

Query:  303 RPTGRIVSTITDLNSITFIGSLK----PMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAA--HNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGI 2081
            +PTG+IV  I   N   F G L       +T  +F P +R  P I IET        QA  ++         G+ +  A+     +S        ++PN        +  +  +  + LL  + +  + FS   +  +P     + I   +   R+D     + S+DP    DIDDALH + +  GN  VGVHIADVS+FI+P  ALD  A +R +++YL  K I M+P +LS +LCSL  N ++LAFS +  +N + EI+  +FTKSVI  K  L+Y +A   I+ DT+         +   ESL  L+KLA +++++R+++GAL ++   V F  +S+  D          P  LQ K L  +N ++EEFMLLAN + A+ +++ F    P+     A LRKHP+P          + K       +    ++ + ++        K  G S+   +   +A  C            Q V   +  D  FHHYGL  P+YTHFTSPIRRYADI+VHR L+  I  + +    + +  ++A  +N N     ++       + +   +    G    +G ++ +  N++IVL+   G+
Sbjct:  333 KPTGKIVGIIKR-NWRPFCGMLNVSQIKESTRHLFTPADRRIPRIRIET-------RQASTLV---------GQRIMVAIDGWPKNS--------RYPNGHFVRSLGSAGEKGTEEAVLLLEHDVPHQAFSQNVLSFLPKMP--WGITPEDMVKRQDLRHLTVCSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDKEAANRGTTVYLCGKRIDMVPELLSSNLCSLRSNVERLAFSCIWEMNHNAEILKTQFTKSVINSKASLTYAEAQMRID-DTNKK-------DDITESLRGLNKLAKILKRKRIENGALTLSSLEVRFHIDSETHD----------PIDLQTKELMETNSMVEEFMLLANISVAQKIYDEF----PD----CALLRKHPAPPPSNYDILLKAAKSMNVEIHTDSAKALADSLDVA------KVDGFSYFNTLLRILATRCMM----------QAVYFCSGMDSDFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAIGADITYPDLMDKHKQSALCNNLNYRHKMSQYAQRASVAFHTQLFFKSRGILNEEGFVLFVRKNAIIVLIPKFGL 862          

Query:  123 NIHIISLLPISEWLFREKFRVLNFNESKFSWYLKNSFPEKNSLIDKPLNSYLFVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFH-DKFQQ---FPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEE--FVIPQHERDNRKDFT-AECXXXXXXXXXXXXXXALHIQAVSGGNYL-VGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEK--FTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEK------------AVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIP-EPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQ-IQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAII---KGENSCGISLSQR--LEAAHNCNVSRIANRRMNDNLTSVYMASYLN----QVGWRLVK-GILINITGNSVIVLLTSSGI 2081
            ++ ++ LLP SEW    + R     E +      +  P+     +KP+             PTGR+V  +            +    +++ +P          +  +  S   Q    + W +  +PK ++  +    + +H ++   D ++    +PN  S        +L++ +  +L    +   PFS+  M+ +P S+ E  + +   E   R+D   +  + SIDP   +D+DD L +++++GG  L +GVHIADV++F+   +  D  A  RA++ YL  +   MLP +LS  LCSL    D+ A S++  ++  G +   +  F ++VIR  ++L Y+ A AL+NG+        P  E+             +++L +L +++  +R +R   GAL +    V    +  +    N    +P +P  +        +  + E M+ AN   A+ +  +F    PN     A LR+HP P     S+  D+ K  GF  +++   ++ + +++ +   +P     L  +    M+ A Y        F+   Q       P   ++HYGL +  YTHFTSPIRRYAD+VVHR L+A +   +G    GI  + R   E A + N      +R     T ++   +      Q   R V   I+  I  N V+V +   GI
Sbjct:  285 DVVVVELLPRSEW----RGRATLLTEGQGD----DRSPDDGQ--EKPM-------------PTGRVVGVLQ-----------RNWRDYVVTFPSR--------DASQSQSRSCQRVLTVPW-DRRIPKIRISTQQAEALQDHRVVVRLDSWESTSLYPNGHSVKVLGRAGELETEVQTILVENCIHVPPFSEAQMKEMPLSSPEKPWRVDPAEVARRRDLRDSHLVFSIDPLGCEDVDDTLSVRSLAGGTLLELGVHIADVTHFVPEGSLTDLEARTRATTYYLADRRYDMLPAVLSADLCSLLGGVDRYAMSVLWELDA-GSLAVRRVWFGRTVIRSSYQLHYELAQALLNGEE----VRVPELERFCPEEKDLKLAQLIQALEMLTRVSRHLRLQRDRGGALELEGVEVRAQLDKDK----NITALVPRQPLEV--------HETVAECMIYANHWVARKIQESF----PNR----ALLRRHPPPRLELFSQLVDTAKAMGFSVDTRTNKALADSLDRAVDPQDPMVNRLLRMMATRAMSQALY--------FSTGSQ-------PQDQYYHYGLALDRYTHFTSPIRRYADMVVHRLLTAALELEQGAGPAGILATNRELEELAQHINNKNWTAQRAQSASTGLFQCLFFRDRDPQTDLRCVADAIIYAIRDNGVLVFVPEYGI 888          

Query:  123 NIHIISLLPISEWLFREKFRVLNFNESKFSWYLKNSFPEKNSLIDKPLNSYLFVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFH-DKFQQ---FPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEE--FVIPQHERDNRKDFT-AECXXXXXXXXXXXXXXALHIQAVSGGNYL-VGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEK--FTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEK------------AVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIP-EPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQ-IQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAII---KGENSCGISLSQR--LEAAHNCNVSRIANRRMNDNLTSVYMASYLN----QVGWRLVK-GILINITGNSVIVLLTSSGI 2081
            ++ ++ LLP SEW    + R     E +      +  P+     +KP+             PTGR+V  +            +    +++ +P          +  +  S   Q    + W +  +PK ++  +    + +H ++   D ++    +PN  S        +L++ +  +L    +   PFS+  M+ +P S+ E  + +   E   R+D   +  + SIDP   +D+DD L +++++GG  L +GVHIADV++F+   +  D  A  RA++ YL  +   MLP +LS  LCSL    D+ A S++  ++  G +   +  F ++VIR  ++L Y+ A AL+NG+        P  E+             +++L +L +++  +R +R   GAL +    V    +  +    N    +P +P  +        +  + E M+ AN   A+ +  +F    PN     A LR+HP P     S+  D+ K  GF  +++   ++ + +++ +   +P     L  +    M+ A Y        F+   Q       P   ++HYGL +  YTHFTSPIRRYAD+VVHR L+A +   +G    GI  + R   E A + N      +R     T ++   +      Q   R V   I+  I  N V+V +   GI
Sbjct:  279 DVVVVELLPRSEW----RGRATLLTEGQGD----DRSPDDGQ--EKPM-------------PTGRVVGVLQ-----------RNWRDYVVTFPSR--------DASQSQSRSCQRVLTVPW-DRRIPKIRISTQQAEALQDHRVVVRLDSWESTSLYPNGHSVKVLGRAGELETEVQTILVENCIHVPPFSEAQMKEMPLSSPEKPWRVDPAEVARRRDLRDSHLVFSIDPLGCEDVDDTLSVRSLAGGTLLELGVHIADVTHFVPEGSLTDLEARTRATTYYLADRRYDMLPAVLSADLCSLLGGVDRYAMSVLWELDA-GSLAVRRVWFGRTVIRSSYQLHYELAQALLNGEE----VRVPELERFCPEEKDLKLAQLIQALEMLTRVSRHLRLQRDRGGALELEGVEVRAQLDKDK----NITALVPRQPLEV--------HETVAECMIYANHWVARKIQESF----PNR----ALLRRHPPPRLELFSQLVDTAKAMGFSVDTRTNKALADSLDRAVDPQDPMVNRLLRMMATRAMSQALY--------FSTGSQ-------PQDQYYHYGLALDRYTHFTSPIRRYADMVVHRLLTAALELEQGAGPAGILATNRELEELAQHINNKNWTAQRAQSASTGLFQCLFFRDRDPQTDLRCVADAIIYAIRDNGVLVFVPEYGI 882          

Query:    3 CYVMKVPVIYFTXXXXXXXXXXXXXXXXXXXDKVDPKQAENIHIISLLPISEWLFREKFRVLNFNESKFSWYLKNSFPEKNSLIDKPLNSYLFVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAKKNTPVAVSLTYNSNKEDYSITMDKGFPRYVYRKEDDEKPGVENVDWNKLLVKNHSKSRGKMQIDLVLSKEEEIEGDSTTQEMNCLSQDKREIRCADXXXXXXXXXXXXXAIYCKDNLLALSVELPFPPISSMLDEDSNRIS 2570
            CYVMKVP++  + S +               DKVDPKQAENIHIISLLPISEWLFREKFRVLNFNESKFSWYLKNSFPEKNSLIDKPLNSYLFVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLK+YKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECIISIDPDDAKDIDDALHIQAVSGGNYLVGVHIADVSYFIKPDTALD TALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATN HYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLL SSGILHRCELRELAPWASRYVEQKAKKNTPVAVSLTYNSNKEDYSITMDKGFPRYVYRKEDDEKPGVENVDWNKLLVKNHSKSRGKMQIDLVLSKEEEIEGDSTTQEMNCLSQDK+EIRCADELFNLTLFEELNFAIYCKDNLLALSVELPFPPISSMLDEDSNRIS
Sbjct:   56 CYVMKVPILGISISIL---------------DKVDPKQAENIHIISLLPISEWLFREKFRVLNFNESKFSWYLKNSFPEKNSLIDKPLNSYLFVNFLTKLRPTGRIVSTITDLNSITFIGSLKPMNTHLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFHDKFQQFPNADSTHKQAAVKDLKSAISNLLKVYKLTDEPFSDKDMECVPASAEEFVIPQHERDNRKDFTAECIISIDPDDAKDIDDALHIQAVSGGNYLVGVHIADVSYFIKPDTALDCTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNLHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLMSSGILHRCELRELAPWASRYVEQKAKKNTPVAVSLTYNSNKEDYSITMDKGFPRYVYRKEDDEKPGVENVDWNKLLVKNHSKSRGKMQIDLVLSKEEEIEGDSTTQEMNCLSQDKKEIRCADELFNLTLFEELNFAIYCKDNLLALSVELPFPPISSMLDEDSNRIS 896          

Query:  678 FSDKDMECVPASAEEFVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAV----SGGNYL--VGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYE--------KAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSP---------EKIKKSRWYDSCKRAGFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAII---------KGENSCG-------ISLSQRLEA------AHNCNVSRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRELAPWASRYVEQKAK 2147
            F +K +  +P    +  + + +   R+D+  EC++S+DP  A+D+DDALHI+ +    + G  L  VG+HIADV+Y+++PD+ +D  A HR +++Y+  + +PMLP  L E+LCSLNP  DKLA+S++  I  + EI+     +++IR   KLSY+ A  +I+  T S        E            S+L L  LA  +R  R  SG+L IN+P + F            N S   P G     LG SN +IEE+ML AN + A+ L  +        S   AFLR+H SP         ++  +  W   C   G   E +DL  +      I ++  H  + +       M +A Y C       ND    +          HH+ LNVPLYTHFTSPIRRY D++VHRQL+ I+         +G+   G        +LS+   A      A  CN  R   +  +++  +++ + ++ + G     GI++ I   +  V L+  G   R  L ++    S Y++ K +
Sbjct:  244 FDEKLLSSIP----KITMTEDDLKYRRDYRNECVVSVDPKTARDLDDALHIKRLCEKSNNGETLWEVGIHIADVTYYVRPDSEVDVEARHRTTTVYMVDRAVPMLPRELCENLCSLNPGTDKLAYSVVFKITDNCEILETWIGRTIIRTACKLSYEDAQNVIDNPTKSDWKNEDFNEVFPPFTTDNVASSILNLHNLAVKMRINRFHSGSLWINQPKLGFML----------NSSRDSPVGYNIYKLGPSNHMIEEWMLRANMSIAEFLHKH--------SPGKAFLRRHESPTIQAINGLNKQFTQIGWKHLCIEKGTTEEFQDLMQLFP----ISDSNYHVMMNICSKV---MQLALYFC------LNDESGGM-------IGCHHFALNVPLYTHFTSPIRRYPDMIVHRQLTEILMKIESEKKNQGDKIQGKLEWMAPTALSKHCTATALDHIADICNKKRKDAKAADESSITLFYSLFVQKCGPFNENGIVVGILDKAFDVFLSHCGFTKRVYLDQIDKNKSVYLKNKGR 736          

Query:  306 PTGRIVSTITDLNSITFIGSLKPMN----THLMFWPYNRGCPEIHIETDKKYSADNQACKIIEWTNHSVPKGKLLFEALPTIYNHSLIFH-DKF---QQFPNADSTHKQAAVKDLKSAISNLLKIYKLTDEPFSDKDMECVPASAEE--FVIPQHERDNRKDFTAECXXXXXXXXXXXXXXALHIQAVSGGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKHKVIPMLPPILSEHLCSLNPNEDKLAFSIMLLINPDGEIISEKFTKSVIRPKFKLSYKQANALING--DTDSSLATNP--------------HYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRAGFR---PESKDLNSIMEVVNQIQETEPHKALGLSFLTYINMNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNV-------SRIANRRMNDNLTSVYMASYLNQVGWRLVKGILINITGNSVIVLLTSSGILHRCELRE 2105
            PTGR+V  I+  N   ++ S +  +     +++  PY+R  P I I      SAD                          + NH  I   D +    ++PN         + DL++    LL  Y L + PF+   +  +P + +E  + +   E   R+D     I SIDP   +D+DD L I+ ++ GN  +GVHIADV++F+KP + LD  A  R++SIY+  +   MLP +LS  LCSL  + D+ A S++  + PD E++S  + +SVIR  +KL Y+ A  + +   D ++SL   P               +++   ++ +L  ++++++ RR+++G L +    V   F   E           +   L  K     +  I E M+ AN   AK    N+    P  S     LR HPSP               GF      + +L   +++    Q+ E +K   L  L  + M+ A+Y  +   L   D              ++HYGL +P YTHFTSPIRRYADI+VHR L   I+G     +  +  L  A  CN+       +++  R   +   +++  +       R  +G+++ +  N  +V +   GI     LR+
Sbjct:  359 PTGRVVG-ISRRNWRDYVCSFEKSDLNAGQYVLVTPYDRRIPMIRIGIT---SADK-------------------------LINHRFIVRIDGWPLSSRYPNGHFVESIGVIGDLETETRTLLIEYNLYNRPFTTSQLAELPINTKENPWKMNPEEVSKRRDLRELLIFSIDPIGCQDVDDTLSIRKLANGNLELGVHIADVTHFVKPHSLLDLEARKRSTSIYMADRRFDMLPHVLSGDLCSLWSDVDRYAVSVVWELTPDIEVVSVDYFRSVIRSSYKLHYELAQDIYDSKIDFETSLGLIPELASKHKAFKDGAERFQQLKSAVTMLINVSSILKSRRIEAGGLELEGMEVQVKFSDPER---------TKLEDLHQKEPLEVHETIAECMIFANHWVAKKCLENY----PTRS----CLRHHPSPRMDHFVELIHCATTKGFTINFSSNLELAKSLDLAVDNQDMETNKI--LRSLATMAMSNAQY-FSTGMLKAED--------------YYHYGLALPTYTHFTSPIRRYADILVHRILLCSIEGVPEESLLTNSSL--ADQCNIMNNQHRQAQLVQRASIELFQAMFFRNKAQDDIARYTEGVIVKLRSNGFVVHIPRYGIKGSVFLRK 929          

Query:  843 GGNYLVGVHIADVSYFIKPDTALDSTALHRASSIYLKH----KVIPMLPPILSEHLCSLNPNEDKLAFSIM------LLINPD---GEIISEKFTKSVIRPKFKLSY-------KQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNF-----LSSRPNESEIGAFLRKHPSPEKIK-KSRWYDSCKRAGFRPESKDL-------NSIMEVVNQIQETEPHKALGL-SFLTYIN---MNVAEYCCAENCLSFNDPEQEVKIINDPDFPFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAIIKGENSCGISLSQRLEAAHNCNVSRIANRRMNDN 1964
            G + ++GVHI DV+ +I P   +   A  R  + Y         I +L   L+  + SL PN+ +   S++      +LINPD    EII   F + VI  +FKL+Y       KQ N + N   +   A N  +            +A  IR+ R+     +    +VN  ++  + ++                 +  +  +IEEFMLLAN+  A+ ++  +     L  +      G +L    +   +    +  + C     RP++ D         +  E  N     +  KA  L  +  Y N   +++ E+         N P +    + D      H+ LN PLYTHFTSPIRR+ DIVVHR L +++ G     I+    L+    C    IAN+++N N
Sbjct:  591 GSDIIIGVHITDVTKYISPTHEIYKQAESRFCTYYPPKFSNIHPIHLLDDTLATDVLSLAPNKPRAVVSVLFRFPGRMLINPDFKLSEIIQPTFRQGVIISQFKLTYEEVSSWLKQPNQIPNDKENLIYALNEIFA-----------VAKKIRRARLPESYFVC---SVNDCYKDMDIET-----------------IFEARIVIEEFMLLANEYVARKIYEKYPDFTLLRMQDPVKNCGEWLENLFNLTNMNFAGQLKEFCNLLNVRPDNFDARKKLIVSKNFYEQFNNFLSIDIDKARSLLQYDAYYNDFFVHIREW------YQMNYPARYECSVKD-SIENKHFSLNKPLYTHFTSPIRRFTDIVVHRLLKSVLNGTEIDDIT----LDIGEVCT---IANKKLNGN 956          

Query:  855 LVGVHIADVSYFIKPDTALDSTALHRASSIYL-KHKVIP---MLPPILSEHLCSLNPNEDKLAFSIML-----LINPD----GEIISEKFTKSVIRPKFKLSYKQANALINGDTDSSLATNPHYEKAVESLLILDKLATVIRKRRVDSGALIINKPTVNFTFESKEFDSSNTNDSIPEPNGLQWKILGRSNFLIEEFMLLANQASAKLLFNNFLSSRPNESEIGAFLRKHPSPEKIKKSRWYDSCKRA---GFRPESKDLNSIMEVVNQIQETEPHKALGLSFLTYIN--MNVAEYCCAENCLSFNDPEQEVKI-------INDPDF---------PFHHYGLNVPLYTHFTSPIRRYADIVVHRQLSAII 1865
            ++GVHI+DV+ ++ P + +   A     + Y  K+  IP   +    L+    SL P + +   S++      +IN       +I+  +F + VI  K+KL+Y++ +  +    D +      Y  A+ES+    K+A  IR  R+             +++  +   +  TN        LQ +    +  LIEEFMLLAN+  A++++  +    PN +     L +  SP K  +  W ++   +    F  + K+  +++ V+N  + +     +   F    N  +  +++  A+  L +++   E  +       I++P +            H+ LN  LYTHFTSPIRR+ D+VVHR L ++I
Sbjct:  302 VIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKLSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLY-MALESVY---KIARKIRHARLP------------YSYFVRSVKNCYTN--------LQTENRFEAELLIEEFMLLANEYVARIIYEKY----PNST-----LLRMQSPVK-NREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVI 638