Tyrosine-protein phosphatase non-receptor type

Overview
NameTyrosine-protein phosphatase non-receptor type
Smed IDSMED30034196
Length (bp)3680
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Tyrosine-protein phosphatase non-receptor type (SMED30034196) t-SNE clustered cells

Violin plots show distribution of expression levels for Tyrosine-protein phosphatase non-receptor type (SMED30034196) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tyrosine-protein phosphatase non-receptor type (SMED30034196) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tyrosine-protein phosphatase non-receptor type (SMED30034196) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30034196

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30034196SMESG000023435.1 dd_Smed_v4_6928_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30034196SMESG000023435.1 dd_Smed_v4_6928_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30034196SMESG000023435.1 dd_Smed_v4_6928_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30034196SMESG000023435.1 dd_Smed_v4_6928_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30034196SMESG000023435.1 dd_Smed_v4_6928_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Human
Match: PTPN4 (protein tyrosine phosphatase non-receptor type 4 [Source:HGNC Symbol;Acc:HGNC:9656])

HSP 1 Score: 336.265 bits (861), Expect = 4.507e-98
Identity = 180/411 (43.80%), Postives = 258/411 (62.77%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPP-LPRKNLVND---IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGL-QIFCESEKCIDTFVLREFRL--KKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            I  D  V I M+P +  ++GF +KGG D K PVIV++V P T AD C P+L EGDQ++ IN     E T+D++   IK++   +    L L+V+P    +V E    N  E D   +P   P  ++  D   +R ++  L + L  G+ +  F++LY++K G+TM+ AK  +NI+KNRY+DI PYD TR+++K N DYINAN I +EIP   +S+ + +YIA QGP+ HT +DF  M WE  S +VVMLT  +E+GR KC++YWP+   T    +G  Q+ C SE+    ++ R+  L  ++ NE+R  T +QYI WPDH VP    DFL F+  +R  R+ + EP+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  QY FVC AI+  Y
Sbjct:  510 IPHDNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCE-RHSGELMLLVRPNAVYDVVEEKLEN--EPDFQYIPEKAPLDSVHQDDHSLRESMIQLAEGLITGTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGNEDYINANYINMEIP---SSSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPE--PTGSSSYGCYQVTCHSEEGNTAYIFRKMTLFNQEKNESRPLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKRAGKEEPVVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVY 912

HSP 2 Score: 187.963 bits (476), Expect = 5.059e-48
Identity = 124/395 (31.39%), Postives = 195/395 (49.37%), Query Frame = 2 
Query:  143 NKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRR 1324
             ++YNV A+E A ++  ++ +   + LLD T + F ++    G   LD V   L++ E+DYFG+Q  DD    +N   +WL  NK +RKQ+K   S  +  FRV+F  ++  ++QE YTRYQ F QIKQDI   ++ C  + A  LA  ++QSELGDY  S   + Y+ ++ FIP+Q   FE ++A  H+   GL P +AE  Y+NTA+ L  YG +  Y     ++++  G+ + GI +Y +    NT+  PW  I K+  K K F ++L                            +H+   + L F      A K  W   +E H+FFR+  P   ++         +F +     + GR  + + +   +     DR FAR PSK   R+
Sbjct:   10 GRTYNVRASELA-RDRQHTEVVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADD--STDNP--RWLDPNKPIRKQLKRG-SPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVRMNTF--PWLKIVKISFKCKQFFIQL-------------------------RKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRLDRPLPPQKNFFAH----YFTLGSKFRYCGRTEV-QSVQYGKEKANKDRVFARSPSKPLARK 366
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Human
Match: PTPN3 (protein tyrosine phosphatase non-receptor type 3 [Source:HGNC Symbol;Acc:HGNC:9655])

HSP 1 Score: 323.939 bits (829), Expect = 2.046e-95
Identity = 163/393 (41.48%), Postives = 243/393 (61.83%), Query Frame = 2 
Query: 2015 DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEE--DEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            D K+GF +KGG D K P++V+++ P + AD C PKL EGDQI+ IN     E T+D++   IK++        L LV++ R   +  +  S +   +   E   P  P     + +  ++  L+  L+ G+ +  FE+LY++K GL +  AK  +N++KNRYKD+LPYD TR++++ N DYINA+ + +EIP +     V KYIA+QGP+ HT + F  ++W+ K  L+VMLT L E+GR+KC++YWPD  + +    G  I C+SE C   +V RE  +   ++ E    THLQY+ WPDH VP    DFL F+  +R +R   SEP++VHCSAGIGRTGV++TM+ A+   E       L IV+ +R+QRAM++Q+  QY+FVC AI+  Y
Sbjct:  342 DGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE-SHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGG--DTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAA---NLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMN-HGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVD-SEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVY 726

HSP 2 Score: 92.4337 bits (228), Expect = 2.846e-18
Identity = 63/206 (30.58%), Postives = 97/206 (47.09%), Query Frame = 2 
Query:  530 DIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ-LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            DI   +++C  + AV LA  ++QS  GDY+SS     Y+ +  FIPDQN  F + V S H+   GLK  +AE  YIN A+ L  YG +L++ + L +  +  G+ + G+ VY      + Y  PW +I K+  K K F +                    QR  +A+S          + F      + K  W + +E H+FF+ K
Sbjct:    2 DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFY--PWVNILKISFKRKKFFIH-------------------QRQKQAESR------EHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 180
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Human
Match: PTPN3 (protein tyrosine phosphatase non-receptor type 3 [Source:HGNC Symbol;Acc:HGNC:9655])

HSP 1 Score: 323.939 bits (829), Expect = 5.124e-95
Identity = 163/393 (41.48%), Postives = 243/393 (61.83%), Query Frame = 2 
Query: 2015 DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEE--DEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            D K+GF +KGG D K P++V+++ P + AD C PKL EGDQI+ IN     E T+D++   IK++        L LV++ R   +  +  S +   +   E   P  P     + +  ++  L+  L+ G+ +  FE+LY++K GL +  AK  +N++KNRYKD+LPYD TR++++ N DYINA+ + +EIP +     V KYIA+QGP+ HT + F  ++W+ K  L+VMLT L E+GR+KC++YWPD  + +    G  I C+SE C   +V RE  +   ++ E    THLQY+ WPDH VP    DFL F+  +R +R   SEP++VHCSAGIGRTGV++TM+ A+   E       L IV+ +R+QRAM++Q+  QY+FVC AI+  Y
Sbjct:  387 DGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE-SHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGG--DTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAA---NLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMN-HGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVD-SEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVY 771

HSP 2 Score: 92.4337 bits (228), Expect = 3.061e-18
Identity = 63/206 (30.58%), Postives = 97/206 (47.09%), Query Frame = 2 
Query:  530 DIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ-LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            DI   +++C  + AV LA  ++QS  GDY+SS     Y+ +  FIPDQN  F + V S H+   GLK  +AE  YIN A+ L  YG +L++ + L +  +  G+ + G+ VY      + Y  PW +I K+  K K F +                    QR  +A+S          + F      + K  W + +E H+FF+ K
Sbjct:    2 DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFY--PWVNILKISFKRKKFFIH-------------------QRQKQAESR------EHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 180
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Human
Match: PTPN3 (protein tyrosine phosphatase non-receptor type 3 [Source:HGNC Symbol;Acc:HGNC:9655])

HSP 1 Score: 323.939 bits (829), Expect = 7.284e-94
Identity = 163/393 (41.48%), Postives = 243/393 (61.83%), Query Frame = 2 
Query: 2015 DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEE--DEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            D K+GF +KGG D K P++V+++ P + AD C PKL EGDQI+ IN     E T+D++   IK++        L LV++ R   +  +  S +   +   E   P  P     + +  ++  L+  L+ G+ +  FE+LY++K GL +  AK  +N++KNRYKD+LPYD TR++++ N DYINA+ + +EIP +     V KYIA+QGP+ HT + F  ++W+ K  L+VMLT L E+GR+KC++YWPD  + +    G  I C+SE C   +V RE  +   ++ E    THLQY+ WPDH VP    DFL F+  +R +R   SEP++VHCSAGIGRTGV++TM+ A+   E       L IV+ +R+QRAM++Q+  QY+FVC AI+  Y
Sbjct:  518 DGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE-SHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGG--DTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAA---NLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMN-HGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVD-SEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVY 902

HSP 2 Score: 155.221 bits (391), Expect = 1.007e-37
Identity = 102/322 (31.68%), Postives = 162/322 (50.31%), Query Frame = 2 
Query:  182 KELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ-LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            KE   S +   +  LD   + F ++ + TG   LD V + L + E++YFG+Q+  DDD +++   +WL+ +K +RKQ+K      T +FRVRF   +   +Q+  TR+  F Q+K DI   +++C  + AV LA  ++QS  GDY+SS     Y+ +  FIPDQN  F + V S H+   GLK  +AE  YIN A+ L  YG +L++ + L +  +  G+ + G+ VY      + Y  PW +I K+  K K F +                    QR  +A+S          + F      + K  W + +E H+FF+ K
Sbjct:   22 KEKTRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQH--DDDSVDSP--RWLEASKAIRKQLKGGFPC-TLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFY--PWVNILKISFKRKKFFIH-------------------QRQKQAESR------EHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 311
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Human
Match: PTPN3 (protein tyrosine phosphatase non-receptor type 3 [Source:HGNC Symbol;Acc:HGNC:9655])

HSP 1 Score: 213.386 bits (542), Expect = 1.941e-56
Identity = 110/289 (38.06%), Postives = 172/289 (59.52%), Query Frame = 2 
Query: 2015 DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEE--DEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKF 2872
            D K+GF +KGG D K P++V+++ P + AD C PKL EGDQI+ IN     E T+D++   IK++        L LV++ R   +  +  S +   +   E   P  P     + +  ++  L+  L+ G+ +  FE+LY++K GL +  AK  +N++KNRYKD+LPYD TR++++ N DYINA+ + +EIP +     V KYIA+QGP+ HT + F  ++W+ K  L+VMLT L E+GR+KC++YWPD  + +    G  I C+SE C   +V RE  +  +  +R  
Sbjct:  518 DGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE-SHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGG--DTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAA---NLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMN-HGGFHIQCQSEDCTIAYVSREMLVTNTQVSRSL 799

HSP 2 Score: 155.606 bits (392), Expect = 5.868e-38
Identity = 102/322 (31.68%), Postives = 162/322 (50.31%), Query Frame = 2 
Query:  182 KELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ-LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            KE   S +   +  LD   + F ++ + TG   LD V + L + E++YFG+Q+  DDD +++   +WL+ +K +RKQ+K      T +FRVRF   +   +Q+  TR+  F Q+K DI   +++C  + AV LA  ++QS  GDY+SS     Y+ +  FIPDQN  F + V S H+   GLK  +AE  YIN A+ L  YG +L++ + L +  +  G+ + G+ VY      + Y  PW +I K+  K K F +                    QR  +A+S          + F      + K  W + +E H+FF+ K
Sbjct:   22 KEKTRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQH--DDDSVDSP--RWLEASKAIRKQLKGGFPC-TLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFY--PWVNILKISFKRKKFFIH-------------------QRQKQAESR------EHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 311
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Celegans
Match: ptp-1 (Tyrosine-protein phosphatase 1 [Source:UniProtKB/Swiss-Prot;Acc:P28191])

HSP 1 Score: 330.102 bits (845), Expect = 1.075e-99
Identity = 170/415 (40.96%), Postives = 251/415 (60.48%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRP-IDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRK---NLVNDIRLT--IKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREF--RLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            +  D  V I MRP    ++GF +KGG D   PVIV++V P ++AD+C P+L EGDQ++ I+      +++D + + I+S  S      L+L ++P +Y   +E       +E + ++ P P +   ++ N  +L+  ++ L DSL  G  V  FE LY++K G++MN  + + N+ KNRY+D+ PYD TR+ ++ S   DYINAN + +EIP   +S  V +YIA QGP+ HTSSDF  M+WE     +VMLT + E+GR KC++YWP   ET +    L I C  +K       REF  R + S+E R+ T +QYI WPDH VP     F+ F+  +R+ R    +PIVVHCSAGIGRTGV+I M+ A   +E  +    L IV+ +R+QRAMLIQ+  QY FVC +I+  Y++
Sbjct:  173 VGEDQVVTIKMRPDRHGRFGFNVKGGADQNYPVIVSRVAPGSSADKCQPRLNEGDQVLFIDGRDVSTMSHDHVVQFIRSARSGLNGGELHLTIRPNVYRLGEE------VDEPDSTMVPEPARVADSVPNSDKLSKSLQLLADSLNSGKVVDHFEMLYRKKPGMSMNICRLTANLAKNRYRDVCPYDDTRVTLQASPSGDYINANYVNMEIP---SSGIVNRYIACQGPLAHTSSDFWVMVWEQHCTTIVMLTTITERGRVKCHQYWPRVFETQEYGR-LMIKCIKDKQTTNCCYREFSIRDRNSSEERRVTQMQYIAWPDHGVPDDPKHFIQFVDEVRKARQGSVDPIVVHCSAGIGRTGVLILMETAACLVESNEPVYPLDIVRTMRDQRAMLIQTPGQYTFVCESILRAYHD 577
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Celegans
Match: ptp-1 (Tyrosine-protein phosphatase 1 [Source:UniProtKB/Swiss-Prot;Acc:P28191])

HSP 1 Score: 330.102 bits (845), Expect = 1.075e-99
Identity = 170/415 (40.96%), Postives = 251/415 (60.48%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRP-IDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRK---NLVNDIRLT--IKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREF--RLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            +  D  V I MRP    ++GF +KGG D   PVIV++V P ++AD+C P+L EGDQ++ I+      +++D + + I+S  S      L+L ++P +Y   +E       +E + ++ P P +   ++ N  +L+  ++ L DSL  G  V  FE LY++K G++MN  + + N+ KNRY+D+ PYD TR+ ++ S   DYINAN + +EIP   +S  V +YIA QGP+ HTSSDF  M+WE     +VMLT + E+GR KC++YWP   ET +    L I C  +K       REF  R + S+E R+ T +QYI WPDH VP     F+ F+  +R+ R    +PIVVHCSAGIGRTGV+I M+ A   +E  +    L IV+ +R+QRAMLIQ+  QY FVC +I+  Y++
Sbjct:  173 VGEDQVVTIKMRPDRHGRFGFNVKGGADQNYPVIVSRVAPGSSADKCQPRLNEGDQVLFIDGRDVSTMSHDHVVQFIRSARSGLNGGELHLTIRPNVYRLGEE------VDEPDSTMVPEPARVADSVPNSDKLSKSLQLLADSLNSGKVVDHFEMLYRKKPGMSMNICRLTANLAKNRYRDVCPYDDTRVTLQASPSGDYINANYVNMEIP---SSGIVNRYIACQGPLAHTSSDFWVMVWEQHCTTIVMLTTITERGRVKCHQYWPRVFETQEYGR-LMIKCIKDKQTTNCCYREFSIRDRNSSEERRVTQMQYIAWPDHGVPDDPKHFIQFVDEVRKARQGSVDPIVVHCSAGIGRTGVLILMETAACLVESNEPVYPLDIVRTMRDQRAMLIQTPGQYTFVCESILRAYHD 577
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Celegans
Match: ptp-1 (Tyrosine-protein phosphatase 1 [Source:UniProtKB/Swiss-Prot;Acc:P28191])

HSP 1 Score: 330.102 bits (845), Expect = 1.075e-99
Identity = 170/415 (40.96%), Postives = 251/415 (60.48%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRP-IDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRK---NLVNDIRLT--IKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREF--RLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            +  D  V I MRP    ++GF +KGG D   PVIV++V P ++AD+C P+L EGDQ++ I+      +++D + + I+S  S      L+L ++P +Y   +E       +E + ++ P P +   ++ N  +L+  ++ L DSL  G  V  FE LY++K G++MN  + + N+ KNRY+D+ PYD TR+ ++ S   DYINAN + +EIP   +S  V +YIA QGP+ HTSSDF  M+WE     +VMLT + E+GR KC++YWP   ET +    L I C  +K       REF  R + S+E R+ T +QYI WPDH VP     F+ F+  +R+ R    +PIVVHCSAGIGRTGV+I M+ A   +E  +    L IV+ +R+QRAMLIQ+  QY FVC +I+  Y++
Sbjct:  173 VGEDQVVTIKMRPDRHGRFGFNVKGGADQNYPVIVSRVAPGSSADKCQPRLNEGDQVLFIDGRDVSTMSHDHVVQFIRSARSGLNGGELHLTIRPNVYRLGEE------VDEPDSTMVPEPARVADSVPNSDKLSKSLQLLADSLNSGKVVDHFEMLYRKKPGMSMNICRLTANLAKNRYRDVCPYDDTRVTLQASPSGDYINANYVNMEIP---SSGIVNRYIACQGPLAHTSSDFWVMVWEQHCTTIVMLTTITERGRVKCHQYWPRVFETQEYGR-LMIKCIKDKQTTNCCYREFSIRDRNSSEERRVTQMQYIAWPDHGVPDDPKHFIQFVDEVRKARQGSVDPIVVHCSAGIGRTGVLILMETAACLVESNEPVYPLDIVRTMRDQRAMLIQTPGQYTFVCESILRAYHD 577
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Celegans
Match: ptp-1 (Tyrosine-protein phosphatase 1 [Source:UniProtKB/Swiss-Prot;Acc:P28191])

HSP 1 Score: 328.176 bits (840), Expect = 1.032e-98
Identity = 170/415 (40.96%), Postives = 251/415 (60.48%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRPI-DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRK---NLVNDIRLT--IKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREF--RLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            +  D  V I MRP    ++GF +KGG D   PVIV++V P ++AD+C P+L EGDQ++ I+      +++D + + I+S  S      L+L ++P +Y   +E       +E + ++ P P +   ++ N  +L+  ++ L DSL  G  V  FE LY++K G++MN  + + N+ KNRY+D+ PYD TR+ ++ S   DYINAN + +EIP   +S  V +YIA QGP+ HTSSDF  M+WE     +VMLT + E+GR KC++YWP   ET +    L I C  +K       REF  R + S+E R+ T +QYI WPDH VP     F+ F+  +R+ R    +PIVVHCSAGIGRTGV+I M+ A   +E  +    L IV+ +R+QRAMLIQ+  QY FVC +I+  Y++
Sbjct:  208 VGEDQVVTIKMRPDRHGRFGFNVKGGADQNYPVIVSRVAPGSSADKCQPRLNEGDQVLFIDGRDVSTMSHDHVVQFIRSARSGLNGGELHLTIRPNVYRLGEE------VDEPDSTMVPEPARVADSVPNSDKLSKSLQLLADSLNSGKVVDHFEMLYRKKPGMSMNICRLTANLAKNRYRDVCPYDDTRVTLQASPSGDYINANYVNMEIP---SSGIVNRYIACQGPLAHTSSDFWVMVWEQHCTTIVMLTTITERGRVKCHQYWPRVFETQEYGR-LMIKCIKDKQTTNCCYREFSIRDRNSSEERRVTQMQYIAWPDHGVPDDPKHFIQFVDEVRKARQGSVDPIVVHCSAGIGRTGVLILMETAACLVESNEPVYPLDIVRTMRDQRAMLIQTPGQYTFVCESILRAYHD 612
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Celegans
Match: ptp-1 (Tyrosine-protein phosphatase 1 [Source:UniProtKB/Swiss-Prot;Acc:P28191])

HSP 1 Score: 328.176 bits (840), Expect = 1.032e-98
Identity = 170/415 (40.96%), Postives = 251/415 (60.48%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRPI-DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRK---NLVNDIRLT--IKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREF--RLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            +  D  V I MRP    ++GF +KGG D   PVIV++V P ++AD+C P+L EGDQ++ I+      +++D + + I+S  S      L+L ++P +Y   +E       +E + ++ P P +   ++ N  +L+  ++ L DSL  G  V  FE LY++K G++MN  + + N+ KNRY+D+ PYD TR+ ++ S   DYINAN + +EIP   +S  V +YIA QGP+ HTSSDF  M+WE     +VMLT + E+GR KC++YWP   ET +    L I C  +K       REF  R + S+E R+ T +QYI WPDH VP     F+ F+  +R+ R    +PIVVHCSAGIGRTGV+I M+ A   +E  +    L IV+ +R+QRAMLIQ+  QY FVC +I+  Y++
Sbjct:  208 VGEDQVVTIKMRPDRHGRFGFNVKGGADQNYPVIVSRVAPGSSADKCQPRLNEGDQVLFIDGRDVSTMSHDHVVQFIRSARSGLNGGELHLTIRPNVYRLGEE------VDEPDSTMVPEPARVADSVPNSDKLSKSLQLLADSLNSGKVVDHFEMLYRKKPGMSMNICRLTANLAKNRYRDVCPYDDTRVTLQASPSGDYINANYVNMEIP---SSGIVNRYIACQGPLAHTSSDFWVMVWEQHCTTIVMLTTITERGRVKCHQYWPRVFETQEYGR-LMIKCIKDKQTTNCCYREFSIRDRNSSEERRVTQMQYIAWPDHGVPDDPKHFIQFVDEVRKARQGSVDPIVVHCSAGIGRTGVLILMETAACLVESNEPVYPLDIVRTMRDQRAMLIQTPGQYTFVCESILRAYHD 612
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Fly
Match: Ptpmeg (gene:FBgn0261985 transcript:FBtr0306563)

HSP 1 Score: 236.884 bits (603), Expect = 5.503e-64
Identity = 130/327 (39.76%), Postives = 187/327 (57.19%), Query Frame = 2 
Query: 2018 SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRL---YLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSL---EDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDT--FVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIR 2965
             +YGF +KGG D   PV V+KV P+T AD+C P++CEGD+++ IN      L ++++  +I+         +L L V+P+     L  +E       E DE         NL++   L  +SL    D L  G+ +  +E +Y++   L + EA+K  N  KNRY+DI PYD TR+ + NS   DYINAN + +EIP       V +YIA+QGP+  T++DF  M+ +  S L+VMLT ++E GR KC++YWP  GE L+L  G  + C SEK  +T  FV REF LK  +E R   H+QY+ WPDH VP   + FL F + +R  R
Sbjct:  513 GRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELL-LTVRPQRSAPLLLEEEPLYQYVPESDEIG----SHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPGG----AVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR 830

HSP 2 Score: 164.851 bits (416), Expect = 6.432e-41
Identity = 113/375 (30.13%), Postives = 179/375 (47.73%), Query Frame = 2 
Query:  209 VKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKT----DISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDD-QVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMF--SGRRTLPELLDIRRRNRLMDRSFARIPSKR 1312
            V V  LD+ +  F +   A G   LD V   LE+ ERDYFG+ +      +     +W+   K  +KQ  +    + ++    FRV+F  ++  ++QE +TRYQ + QIK++I   K+ CS +    LA  ++QSELGD+++   +  Y+   + + DQ    E  V   HK  +G  P DAE  Y+  AK+L  YG DL+     +  ++Q G++A G+ V+      NT+   W+ + KV  K K F ++L                  +R    +   +       L F   +   AK  W + +E HSFFR+K P ++ R         F  ISL + F  SGR  L  + + ++R R+  + F R PSKR
Sbjct:   36 VTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDV----VRWVDAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTF--SWSKMVKVSFKRKDFFIQL------------------RREPSENYDTL-------LGFGMSSHKHAKALWKSCVEHHSFFRLKRPHRLSR---------FLNISLGSKFYYSGRTELQAVQESKQRGRI-HKVFVRSPSKR 369
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Fly
Match: Ptpmeg (gene:FBgn0261985 transcript:FBtr0306559)

HSP 1 Score: 236.884 bits (603), Expect = 5.503e-64
Identity = 130/327 (39.76%), Postives = 187/327 (57.19%), Query Frame = 2 
Query: 2018 SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRL---YLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSL---EDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDT--FVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIR 2965
             +YGF +KGG D   PV V+KV P+T AD+C P++CEGD+++ IN      L ++++  +I+         +L L V+P+     L  +E       E DE         NL++   L  +SL    D L  G+ +  +E +Y++   L + EA+K  N  KNRY+DI PYD TR+ + NS   DYINAN + +EIP       V +YIA+QGP+  T++DF  M+ +  S L+VMLT ++E GR KC++YWP  GE L+L  G  + C SEK  +T  FV REF LK  +E R   H+QY+ WPDH VP   + FL F + +R  R
Sbjct:  513 GRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELL-LTVRPQRSAPLLLEEEPLYQYVPESDEIG----SHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPGG----AVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR 830

HSP 2 Score: 164.851 bits (416), Expect = 6.432e-41
Identity = 113/375 (30.13%), Postives = 179/375 (47.73%), Query Frame = 2 
Query:  209 VKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKT----DISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDD-QVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMF--SGRRTLPELLDIRRRNRLMDRSFARIPSKR 1312
            V V  LD+ +  F +   A G   LD V   LE+ ERDYFG+ +      +     +W+   K  +KQ  +    + ++    FRV+F  ++  ++QE +TRYQ + QIK++I   K+ CS +    LA  ++QSELGD+++   +  Y+   + + DQ    E  V   HK  +G  P DAE  Y+  AK+L  YG DL+     +  ++Q G++A G+ V+      NT+   W+ + KV  K K F ++L                  +R    +   +       L F   +   AK  W + +E HSFFR+K P ++ R         F  ISL + F  SGR  L  + + ++R R+  + F R PSKR
Sbjct:   36 VTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDV----VRWVDAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTF--SWSKMVKVSFKRKDFFIQL------------------RREPSENYDTL-------LGFGMSSHKHAKALWKSCVEHHSFFRLKRPHRLSR---------FLNISLGSKFYYSGRTELQAVQESKQRGRI-HKVFVRSPSKR 369
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Fly
Match: Ptpmeg (gene:FBgn0261985 transcript:FBtr0306560)

HSP 1 Score: 236.884 bits (603), Expect = 5.503e-64
Identity = 130/327 (39.76%), Postives = 187/327 (57.19%), Query Frame = 2 
Query: 2018 SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRL---YLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSL---EDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDT--FVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIR 2965
             +YGF +KGG D   PV V+KV P+T AD+C P++CEGD+++ IN      L ++++  +I+         +L L V+P+     L  +E       E DE         NL++   L  +SL    D L  G+ +  +E +Y++   L + EA+K  N  KNRY+DI PYD TR+ + NS   DYINAN + +EIP       V +YIA+QGP+  T++DF  M+ +  S L+VMLT ++E GR KC++YWP  GE L+L  G  + C SEK  +T  FV REF LK  +E R   H+QY+ WPDH VP   + FL F + +R  R
Sbjct:  513 GRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELL-LTVRPQRSAPLLLEEEPLYQYVPESDEIG----SHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPGG----AVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR 830

HSP 2 Score: 164.851 bits (416), Expect = 6.432e-41
Identity = 113/375 (30.13%), Postives = 179/375 (47.73%), Query Frame = 2 
Query:  209 VKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKT----DISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDD-QVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMF--SGRRTLPELLDIRRRNRLMDRSFARIPSKR 1312
            V V  LD+ +  F +   A G   LD V   LE+ ERDYFG+ +      +     +W+   K  +KQ  +    + ++    FRV+F  ++  ++QE +TRYQ + QIK++I   K+ CS +    LA  ++QSELGD+++   +  Y+   + + DQ    E  V   HK  +G  P DAE  Y+  AK+L  YG DL+     +  ++Q G++A G+ V+      NT+   W+ + KV  K K F ++L                  +R    +   +       L F   +   AK  W + +E HSFFR+K P ++ R         F  ISL + F  SGR  L  + + ++R R+  + F R PSKR
Sbjct:   36 VTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDV----VRWVDAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTF--SWSKMVKVSFKRKDFFIQL------------------RREPSENYDTL-------LGFGMSSHKHAKALWKSCVEHHSFFRLKRPHRLSR---------FLNISLGSKFYYSGRTELQAVQESKQRGRI-HKVFVRSPSKR 369
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Fly
Match: Ptpmeg (gene:FBgn0261985 transcript:FBtr0306561)

HSP 1 Score: 236.884 bits (603), Expect = 5.503e-64
Identity = 130/327 (39.76%), Postives = 187/327 (57.19%), Query Frame = 2 
Query: 2018 SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRL---YLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSL---EDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDT--FVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIR 2965
             +YGF +KGG D   PV V+KV P+T AD+C P++CEGD+++ IN      L ++++  +I+         +L L V+P+     L  +E       E DE         NL++   L  +SL    D L  G+ +  +E +Y++   L + EA+K  N  KNRY+DI PYD TR+ + NS   DYINAN + +EIP       V +YIA+QGP+  T++DF  M+ +  S L+VMLT ++E GR KC++YWP  GE L+L  G  + C SEK  +T  FV REF LK  +E R   H+QY+ WPDH VP   + FL F + +R  R
Sbjct:  513 GRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELL-LTVRPQRSAPLLLEEEPLYQYVPESDEIG----SHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPGG----AVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR 830

HSP 2 Score: 164.851 bits (416), Expect = 6.432e-41
Identity = 113/375 (30.13%), Postives = 179/375 (47.73%), Query Frame = 2 
Query:  209 VKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKT----DISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDD-QVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMF--SGRRTLPELLDIRRRNRLMDRSFARIPSKR 1312
            V V  LD+ +  F +   A G   LD V   LE+ ERDYFG+ +      +     +W+   K  +KQ  +    + ++    FRV+F  ++  ++QE +TRYQ + QIK++I   K+ CS +    LA  ++QSELGD+++   +  Y+   + + DQ    E  V   HK  +G  P DAE  Y+  AK+L  YG DL+     +  ++Q G++A G+ V+      NT+   W+ + KV  K K F ++L                  +R    +   +       L F   +   AK  W + +E HSFFR+K P ++ R         F  ISL + F  SGR  L  + + ++R R+  + F R PSKR
Sbjct:   36 VTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDV----VRWVDAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTF--SWSKMVKVSFKRKDFFIQL------------------RREPSENYDTL-------LGFGMSSHKHAKALWKSCVEHHSFFRLKRPHRLSR---------FLNISLGSKFYYSGRTELQAVQESKQRGRI-HKVFVRSPSKR 369
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Fly
Match: Ptpmeg (gene:FBgn0261985 transcript:FBtr0306562)

HSP 1 Score: 236.884 bits (603), Expect = 5.503e-64
Identity = 130/327 (39.76%), Postives = 187/327 (57.19%), Query Frame = 2 
Query: 2018 SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRL---YLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSL---EDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDT--FVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIR 2965
             +YGF +KGG D   PV V+KV P+T AD+C P++CEGD+++ IN      L ++++  +I+         +L L V+P+     L  +E       E DE         NL++   L  +SL    D L  G+ +  +E +Y++   L + EA+K  N  KNRY+DI PYD TR+ + NS   DYINAN + +EIP       V +YIA+QGP+  T++DF  M+ +  S L+VMLT ++E GR KC++YWP  GE L+L  G  + C SEK  +T  FV REF LK  +E R   H+QY+ WPDH VP   + FL F + +R  R
Sbjct:  513 GRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELL-LTVRPQRSAPLLLEEEPLYQYVPESDEIG----SHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPGG----AVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR 830

HSP 2 Score: 164.851 bits (416), Expect = 6.432e-41
Identity = 113/375 (30.13%), Postives = 179/375 (47.73%), Query Frame = 2 
Query:  209 VKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKT----DISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDD-QVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMF--SGRRTLPELLDIRRRNRLMDRSFARIPSKR 1312
            V V  LD+ +  F +   A G   LD V   LE+ ERDYFG+ +      +     +W+   K  +KQ  +    + ++    FRV+F  ++  ++QE +TRYQ + QIK++I   K+ CS +    LA  ++QSELGD+++   +  Y+   + + DQ    E  V   HK  +G  P DAE  Y+  AK+L  YG DL+     +  ++Q G++A G+ V+      NT+   W+ + KV  K K F ++L                  +R    +   +       L F   +   AK  W + +E HSFFR+K P ++ R         F  ISL + F  SGR  L  + + ++R R+  + F R PSKR
Sbjct:   36 VTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDV----VRWVDAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTF--SWSKMVKVSFKRKDFFIQL------------------RREPSENYDTL-------LGFGMSSHKHAKALWKSCVEHHSFFRLKRPHRLSR---------FLNISLGSKFYYSGRTELQAVQESKQRGRI-HKVFVRSPSKR 369
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Zebrafish
Match: ptpn4b (protein tyrosine phosphatase non-receptor type 4b [Source:ZFIN;Acc:ZDB-GENE-030131-6259])

HSP 1 Score: 342.428 bits (877), Expect = 2.039e-100
Identity = 174/425 (40.94%), Postives = 263/425 (61.88%), Query Frame = 2 
Query: 1928 LSNSTSTMTQSTDKLIDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPP---LPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS-DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYN 3181
            L N  +   +S +  +  D  V I MRP +  ++GF +KGG D + P+IV++V P T AD C P+L EGDQ++ IN     + T+D++  IIK++   +   ++ L+V+P    +VDE     + E D   +P    L   +  + +R +I+ L D L  G+    F++LY+++ G++M+ A+  +N++KNRY+DI PYD TR+V+K + DYINAN I +++P   +   V +YIA QGP+  T SDF  M+WE  + LVVMLT  +E+GR KC++YWP+   +     G Q+ C SE+    ++LR+  L   +S E R+   +QY+ WPDH VP    DFL F+  +R  R+   EP+VVHCSAGIGRTGV+ITM+ A+  +E  QS   L IV+ +R+QRAM+IQ+  QY FVC AI+  Y+
Sbjct:  499 LYNVPAASGKSMNGAVPHDNLVLIKMRPDENGRFGFNVKGGVDQRMPIIVSRVAPGTPADMCVPRLNEGDQVVLINGRDISDHTHDDVVMIIKASCEDQSGELI-LLVRPNAIYDVDEEQEKLDLEPDFQYIPEACGLESHSEADSLRSSIQLLRDGLASGTVPAQFDQLYRKRPGMSMSCARLPQNVSKNRYRDISPYDSTRVVLKGTEDYINANFINMDVP---SKGEVRRYIACQGPLPGTCSDFWQMVWEQSAALVVMLTTQVERGRVKCHQYWPNVSAS-GTYGGFQVTCVSEEGNSAYLLRDLTLTHLESKEERQICQMQYLAWPDHGVPDDSSDFLNFVSQVRSKRADGPEPVVVHCSAGIGRTGVLITMETAMCLIEGGQSVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYD 918

HSP 2 Score: 191.815 bits (486), Expect = 2.332e-49
Identity = 130/405 (32.10%), Postives = 196/405 (48.40%), Query Frame = 2 
Query:  143 NKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSI 1354
             +SY+V A E A +E  ++ ++  V LLD T + F ++ +  G   LD V   LE+ ERDYFG+Q  DD         +WL  NK VRKQ+K   S     FRV+F   +  ++QE YTRY  F Q+KQDI + ++ C ++ AV LA  ++Q+ELGDY  S   + Y+ E+ FIP+    FE +VA  H+   GL P  +E  Y+N A+ L  YG +L Y     + ++  G+ + GI+VY   D       PW  I K+  K+K F ++L                            + +   S L F      A K  W + +E H+FFR++ P   ER   +     +F +     + GR     +   + R    +R FAR PSK   RR   G + +++
Sbjct:   10 GRSYDVGALEEA-RERQHAQVECNVLLLDNTVQTFRVNKQDQGQILLDVVYKHLELTERDYFGLQLADDTSDTQ----RWLDPNKPVRKQLKRP-SPHNLRFRVKFFVGDPGKLQEEYTRYLYFLQLKQDILSGRLPCPQNTAVLLASYAVQAELGDYSHSEHLSGYLSEYSFIPNPPQDFEKEVAKLHQEHNGLTPAQSEFNYLNAARTLELYGVELHYARDHCNTEIYVGVLSAGISVYK--DRVRVNHFPWFKIVKISFKSKQFFIQL-------------------------RKELTECRESLLGFNMMNYRACKNLWKSCVENHTFFRLERPVPPERNLFLH----YFTLGSKFRYCGRTEAQSVQYGKERGN-KNRVFARSPSKPLVRRLMSGLDWETV 376
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Zebrafish
Match: ptpn4a (protein tyrosine phosphatase non-receptor type 4a [Source:ZFIN;Acc:ZDB-GENE-030616-449])

HSP 1 Score: 337.035 bits (863), Expect = 4.908e-99
Identity = 181/441 (41.04%), Postives = 272/441 (61.68%), Query Frame = 2 
Query: 1895 LSGSMSSMKNALSNSTSTMTQSTDKL-----IDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLP---PLPRKNLVNDI-RLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS-DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            LS S   + N + N    +  +TDK+     +  D  V I M+P +  ++GF +KGG D K P+IV++V P T+AD C P+L EGDQ++ IN     E ++D++   IK++       ++ LV    +Y  V+E      TE D   +P   P    +L  D  R ++  L++ L  G+ +  F++LY+++ G+TM+ AK  +NI+KNRY+DI PYD TR+++K + DYINAN I +EIP     + + +YIA QGP+ +T SDF  M WE  S +VVMLT  +E+GR KC++YWP+   +     G QI C++E+    F++RE  L   +S E+R+ T +QY+ WPDH VP    DFL F+ ++R  R+ + EP+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  Q++FVC AI+  Y
Sbjct:  434 LSHSQQDLDNHI-NEMYDVPTATDKVMPNGVVPHDNLVLIKMKPDENGRFGFNVKGGSDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGREIAEHSHDQVVMFIKASCESHSGELILLVRPNAIYDVVEEKLE---TEPDFQYIPEKSPTDPSHLDQDAWRDSMLYLKEGLNSGTILAQFDQLYRKRPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGTEDYINANYINMEIPAC---SLINRYIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPNPSGSATYG-GFQISCQTEEGNSAFLVREITLTHIESGESRELTQIQYLAWPDHGVPDDSTDFLDFVALVRNKRAGKDEPVVVHCSAGIGRTGVLITMETAMCLMECSQPVFPLEIVRTMRDQRAMMIQTPSQFKFVCEAILKVY 866

HSP 2 Score: 173.326 bits (438), Expect = 1.317e-43
Identity = 125/385 (32.47%), Postives = 176/385 (45.71%), Query Frame = 2 
Query:  278 FLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFK--ISLANMFS-GRRTLPELLDIRRRNRLMDRSFARIPSKRYNR------------RNTPGGERQSIVSAETNRPTG 1384
             LD+V   LE+ ERDYFG+   D+         +WL  NK +RKQ+K   S     FRV+F  ++  ++QE YTRYQ F QIKQDI + ++ C  + A  LA  ++QSELGDY  +     Y+ EF FIP+Q   FE DVA  H+   GL P  +E  Y+NTA+ L  YG +L Y     + ++  G+ + GI +Y +  ++  Y  PW  I K+  K K F ++L                             H    + L F      A K  W   +E H+FFR+  P        +   ++FF    SL + F    RT  + +   +   + DR FAR PSK   R            RN+   ER    S  T  P G
Sbjct:    7 LLDAVFKHLELTERDYFGLHLADEPSDSP----RWLDPNKPIRKQLKRG-SPHHLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILSGRLPCPHNTAALLASYAVQSELGDYSEAENLPGYLSEFFFIPNQPQGFEKDVAKHHQQHNGLNPAQSEFNYLNTARTLDLYGVELHYARDQSNTEIYVGVLSAGIGIYKN-RVRINY-FPWLKIVKISFKCKQFFIQL-------------------------RKEAHDTRDTLLGFNMVNYRACKNLWKTCVEHHTFFRLDRP--------VPPQKNFFAHYFSLGSRFRYCGRTEAQSVQYGKEKGIKDRVFARSPSKPLARKLMGVTDWEAVSRNSLSEERLETRSLPTRSPPG 351
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Zebrafish
Match: ptpn4a (protein tyrosine phosphatase non-receptor type 4a [Source:ZFIN;Acc:ZDB-GENE-030616-449])

HSP 1 Score: 337.035 bits (863), Expect = 8.731e-99
Identity = 186/464 (40.09%), Postives = 280/464 (60.34%), Query Frame = 2 
Query: 1826 PKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNSTSTMTQSTDK-----LIDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLP---PLPRKNLVNDI-RLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS-DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            PK SR ++ +L            LS S   + N + N    +  +TDK     ++  D  V I M+P +  ++GF +KGG D K P+IV++V P T+AD C P+L EGDQ++ IN     E ++D++   IK++       ++ LV    +Y  V+E      TE D   +P   P    +L  D  R ++  L++ L  G+ +  F++LY+++ G+TM+ AK  +NI+KNRY+DI PYD TR+++K + DYINAN I +EIP     + + +YIA QGP+ +T SDF  M WE  S +VVMLT  +E+GR KC++YWP+   +     G QI C++E+    F++RE  L   +S E+R+ T +QY+ WPDH VP    DFL F+ ++R  R+ + EP+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  Q++FVC AI+  Y
Sbjct:  453 PKQSRKNLSQLI-----------LSHSQQDLDNHI-NEMYDVPTATDKAMPNGVVPHDNLVLIKMKPDENGRFGFNVKGGSDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGREIAEHSHDQVVMFIKASCESHSGELILLVRPNAIYDVVEEKLE---TEPDFQYIPEKSPTDPSHLDQDAWRDSMLYLKEGLNSGTILAQFDQLYRKRPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGTEDYINANYINMEIPAC---SLINRYIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPNPSGSATYG-GFQISCQTEEGNSAFLVREITLTHIESGESRELTQIQYLAWPDHGVPDDSTDFLDFVALVRNKRAGKDEPVVVHCSAGIGRTGVLITMETAMCLMECSQPVFPLEIVRTMRDQRAMMIQTPSQFKFVCEAILKVY 897

HSP 2 Score: 154.836 bits (390), Expect = 1.088e-37
Identity = 128/430 (29.77%), Postives = 188/430 (43.72%), Query Frame = 2 
Query:  143 NKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFK--ISLANMFS-GRRTLPELLDIRRRNRLMDRSFARIPSKRYNR------------RNTPGGERQSIVSAETNRPTG 1384
             +SYNV   E A ++   + +   + LLD T + F ++ +  G   LD+V   LE+ ERDYFG+   D+         +WL  NK +RKQ+K   S     FRV+F  ++  ++QE YTR               + C  + A  LA  ++QSELGDY  +     Y+ EF FIP+Q   FE DVA  H+   GL P  +E  Y+NTA+ L  YG +L Y     + ++  G+ + GI +Y +  ++  Y  PW  I K+  K K F ++L                             H+   + L F      A K  W   +E H+FFR+  P        +   ++FF    SL + F    RT  + +   +   + DR FAR PSK   R            RN+   ER    S  T  P G
Sbjct:   10 GRSYNVRTTELA-RDRQRTEVVCNILLLDNTVQPFKVNHD-QGQILLDAVFKHLELTERDYFGLHLADEPSDSP----RWLDPNKPIRKQLKRG-SPHHLNFRVKFFVSDPNKLQEEYTR---------------LPCPHNTAALLASYAVQSELGDYSEAENLPGYLSEFFFIPNQPQGFEKDVAKHHQQHNGLNPAQSEFNYLNTARTLDLYGVELHYARDQSNTEIYVGVLSAGIGIYKN-RVRINY-FPWLKIVKISFKCKQFFIQL-------------------------RKEAHETRDTLLGFNMVNYRACKNLWKTCVEHHTFFRLDRP--------VPPQKNFFAHYFSLGSRFRYCGRTEAQSVQYGKEKGIKDRVFARSPSKPLARKLMGVTDWEAVSRNSLSEERLETRSLPTRSPPG 382
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Zebrafish
Match: ptpn4a (protein tyrosine phosphatase non-receptor type 4a [Source:ZFIN;Acc:ZDB-GENE-030616-449])

HSP 1 Score: 337.421 bits (864), Expect = 1.149e-98
Identity = 186/464 (40.09%), Postives = 280/464 (60.34%), Query Frame = 2 
Query: 1826 PKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNSTSTMTQSTDKL-----IDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLP---PLPRKNLVNDI-RLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS-DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            PK SR ++ +L            LS S   + N + N    +  +TDK+     +  D  V I M+P +  ++GF +KGG D K P+IV++V P T+AD C P+L EGDQ++ IN     E ++D++   IK++       ++ LV    +Y  V+E      TE D   +P   P    +L  D  R ++  L++ L  G+ +  F++LY+++ G+TM+ AK  +NI+KNRY+DI PYD TR+++K + DYINAN I +EIP     + + +YIA QGP+ +T SDF  M WE  S +VVMLT  +E+GR KC++YWP+   +     G QI C++E+    F++RE  L   +S E+R+ T +QY+ WPDH VP    DFL F+ ++R  R+ + EP+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  Q++FVC AI+  Y
Sbjct:  468 PKQSRKNLSQLI-----------LSHSQQDLDNHI-NEMYDVPTATDKVMPNGVVPHDNLVLIKMKPDENGRFGFNVKGGSDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGREIAEHSHDQVVMFIKASCESHSGELILLVRPNAIYDVVEEKLE---TEPDFQYIPEKSPTDPSHLDQDAWRDSMLYLKEGLNSGTILAQFDQLYRKRPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGTEDYINANYINMEIPAC---SLINRYIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPNPSGSATYG-GFQISCQTEEGNSAFLVREITLTHIESGESRELTQIQYLAWPDHGVPDDSTDFLDFVALVRNKRAGKDEPVVVHCSAGIGRTGVLITMETAMCLMECSQPVFPLEIVRTMRDQRAMMIQTPSQFKFVCEAILKVY 912

HSP 2 Score: 182.57 bits (462), Expect = 1.775e-46
Identity = 137/430 (31.86%), Postives = 198/430 (46.05%), Query Frame = 2 
Query:  143 NKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFK--ISLANMFS-GRRTLPELLDIRRRNRLMDRSFARIPSKRYNR------------RNTPGGERQSIVSAETNRPTG 1384
             +SYNV   E A ++   + +   + LLD T + F ++ +  G   LD+V   LE+ ERDYFG+   D+         +WL  NK +RKQ+K   S     FRV+F  ++  ++QE YTRYQ F QIKQDI + ++ C  + A  LA  ++QSELGDY  +     Y+ EF FIP+Q   FE DVA  H+   GL P  +E  Y+NTA+ L  YG +L Y     + ++  G+ + GI +Y +  ++  Y  PW  I K+  K K F ++L                             H    + L F      A K  W   +E H+FFR+  P        +   ++FF    SL + F    RT  + +   +   + DR FAR PSK   R            RN+   ER    S  T  P G
Sbjct:   10 GRSYNVRTTELA-RDRQRTEVVCNILLLDNTVQPFKVNHD-QGQILLDAVFKHLELTERDYFGLHLADEPSDSP----RWLDPNKPIRKQLKRG-SPHHLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILSGRLPCPHNTAALLASYAVQSELGDYSEAENLPGYLSEFFFIPNQPQGFEKDVAKHHQQHNGLNPAQSEFNYLNTARTLDLYGVELHYARDQSNTEIYVGVLSAGIGIYKN-RVRINY-FPWLKIVKISFKCKQFFIQL-------------------------RKEAHDTRDTLLGFNMVNYRACKNLWKTCVEHHTFFRLDRP--------VPPQKNFFAHYFSLGSRFRYCGRTEAQSVQYGKEKGIKDRVFARSPSKPLARKLMGVTDWEAVSRNSLSEERLETRSLPTRSPPG 397
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Zebrafish
Match: ptpn4a (protein tyrosine phosphatase non-receptor type 4a [Source:ZFIN;Acc:ZDB-GENE-030616-449])

HSP 1 Score: 337.035 bits (863), Expect = 1.307e-98
Identity = 186/464 (40.09%), Postives = 280/464 (60.34%), Query Frame = 2 
Query: 1826 PKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNSTSTMTQSTDKL-----IDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLP---PLPRKNLVNDI-RLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS-DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            PK SR ++ +L            LS S   + N + N    +  +TDK+     +  D  V I M+P +  ++GF +KGG D K P+IV++V P T+AD C P+L EGDQ++ IN     E ++D++   IK++       ++ LV    +Y  V+E      TE D   +P   P    +L  D  R ++  L++ L  G+ +  F++LY+++ G+TM+ AK  +NI+KNRY+DI PYD TR+++K + DYINAN I +EIP     + + +YIA QGP+ +T SDF  M WE  S +VVMLT  +E+GR KC++YWP+   +     G QI C++E+    F++RE  L   +S E+R+ T +QY+ WPDH VP    DFL F+ ++R  R+ + EP+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  Q++FVC AI+  Y
Sbjct:  469 PKQSRKNLSQLI-----------LSHSQQDLDNHI-NEMYDVPTATDKVMPNGVVPHDNLVLIKMKPDENGRFGFNVKGGSDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGREIAEHSHDQVVMFIKASCESHSGELILLVRPNAIYDVVEEKLE---TEPDFQYIPEKSPTDPSHLDQDAWRDSMLYLKEGLNSGTILAQFDQLYRKRPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGTEDYINANYINMEIPAC---SLINRYIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPNPSGSATYG-GFQISCQTEEGNSAFLVREITLTHIESGESRELTQIQYLAWPDHGVPDDSTDFLDFVALVRNKRAGKDEPVVVHCSAGIGRTGVLITMETAMCLMECSQPVFPLEIVRTMRDQRAMMIQTPSQFKFVCEAILKVY 913

HSP 2 Score: 186.037 bits (471), Expect = 1.544e-47
Identity = 137/430 (31.86%), Postives = 197/430 (45.81%), Query Frame = 2 
Query:  143 NKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFK--ISLANMFS-GRRTLPELLDIRRRNRLMDRSFARIPSKRYNR------------RNTPGGERQSIVSAETNRPTG 1384
             +SYNV   E A ++   + +   + LLD T + F ++    G   LD+V   LE+ ERDYFG+   D+         +WL  NK +RKQ+K   S     FRV+F  ++  ++QE YTRYQ F QIKQDI + ++ C  + A  LA  ++QSELGDY  +     Y+ EF FIP+Q   FE DVA  H+   GL P  +E  Y+NTA+ L  YG +L Y     + ++  G+ + GI +Y +  ++  Y  PW  I K+  K K F ++L                             H    + L F      A K  W   +E H+FFR+  P        +   ++FF    SL + F    RT  + +   +   + DR FAR PSK   R            RN+   ER    S  T  P G
Sbjct:   10 GRSYNVRTTELA-RDRQRTEVVCNILLLDNTVQPFKVNKHDQGQILLDAVFKHLELTERDYFGLHLADEPSDSP----RWLDPNKPIRKQLKRG-SPHHLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILSGRLPCPHNTAALLASYAVQSELGDYSEAENLPGYLSEFFFIPNQPQGFEKDVAKHHQQHNGLNPAQSEFNYLNTARTLDLYGVELHYARDQSNTEIYVGVLSAGIGIYKN-RVRINY-FPWLKIVKISFKCKQFFIQL-------------------------RKEAHDTRDTLLGFNMVNYRACKNLWKTCVEHHTFFRLDRP--------VPPQKNFFAHYFSLGSRFRYCGRTEAQSVQYGKEKGIKDRVFARSPSKPLARKLMGVTDWEAVSRNSLSEERLETRSLPTRSPPG 398
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Xenopus
Match: mon2 (MON2 homolog, regulator of endosome-to-Golgi trafficking [Source:Xenbase;Acc:XB-GENE-975876])

HSP 1 Score: 316.62 bits (810), Expect = 2.413e-91
Identity = 162/399 (40.60%), Postives = 248/399 (62.16%), Query Frame = 2 
Query: 2015 DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDS--LPP--LPRKNLVND-IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSD-YINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRLKKSNETRKFT--HLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            + K+GF +KGG D K  ++V+++ P + AD+C PKL EGDQI+ IN     E T+D++   IK++       ++ LV +      V  H     +E+D D    PP  LP  +   D ++ +++ L   L+ G  +  FE+LY++K GL +  A+  +N++KNRYKD+LPYD TR++++  D YINA+ + +EIP   ++  V KY+A+QGP+ HT   F  M+WE K  +++MLT L E+GR+KC +YWPD  E    ++G  ++ C++E C   +V RE  L  +    +F   HLQY+ WPDH VP    DFL F   +R+ R + ++P++VHCSAGIGRTGV+ITM+ AI  +E  Q    L IV+ +R+QRAM++Q+  QY+FVC AI+  Y +
Sbjct:  505 EGKFGFNLKGGVDQKMQLVVSRITPGSPADKCIPKLKEGDQIVLINGRDISEHTHDQVVMFIKASRESHTRELVLLVRR-----KVVRHLGKTKSEDDADFTFFPPSILPTCSEYGDTLQGSMEQLSKGLETGVVLIQFEQLYRKKPGLAIICARTGQNMDKNRYKDVLPYDATRVLLQGEDDYINASYVNMEIP---STNIVNKYVATQGPLPHTCEQFWQMVWEQKLSIIIMLTTLTERGRTKCQQYWPDPPEVT--EYGKFRVICKTEDCTIAYVFREMLLTNTETGNEFPIFHLQYVAWPDHGVPDDSSDFLEFATCVRKKRVA-NQPVLVHCSAGIGRTGVLITMETAICLIEQNQPVYPLDIVRQMRDQRAMMVQTSSQYKFVCEAILRVYKD 892

HSP 2 Score: 115.161 bits (287), Expect = 2.582e-25
Identity = 92/322 (28.57%), Postives = 149/322 (46.27%), Query Frame = 2 
Query:  182 KELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ-LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            KE   S +   V+ LD +   F ++ + TG   LD V + L + ER++FG+Q+ +D   L++  ++W++ NK +RKQ+K      +  FRVRF   +   +Q+  TR               ISC  + AV LA  ++QSELGD++SS     ++    FIPDQ+  F S V +      GL   +AE  YIN A+ L  YG + ++ + L +  +  G+ + G+ VY    +  T   PW +I K+  K K F +               H +  Q   +             + F      A K  W + +E H+FF+ +
Sbjct:   22 KEKNRSEVVCTVRFLDGSQHCFRVNKQDTGHTLLDMVYNYLNLKEREFFGLQHSED--SLDS--HRWIEPNKPIRKQLKGGFPC-SLLFRVRFFIPDPNTLQQDQTR---------------ISCPLNSAVVLASYAVQSELGDHNSSVHVPGHLSNTSFIPDQDNDFLSKVEAC-----GLGQTEAESCYINIARTLEFYGIETHSGRDLHNLDLLIGIASGGVAVYRK--LICTSFYPWVNILKISFKRKKFFL---------------HQRQKQNECREQI----------VTFNMLNYRACKNVWRSCVEHHTFFQTR 291
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Xenopus
Match: mon2 (MON2 homolog, regulator of endosome-to-Golgi trafficking [Source:Xenbase;Acc:XB-GENE-975876])

HSP 1 Score: 301.212 bits (770), Expect = 3.429e-88
Identity = 165/435 (37.93%), Postives = 262/435 (60.23%), Query Frame = 2 
Query: 1922 NALSNSTSTMTQSTDKLI-----DTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDS--LPP--LPRKNLVND-IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSD-YINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRLKKSNETRKF--THLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
             A++ + S  +Q   K+I     +TD R  +++  +++K   ++    D K  ++V+++ P + AD+C PKL EGDQI+ IN     E T+D++   IK++       ++ LV +      V  H     +E+D D    PP  LP  +   D ++ +++ L   L+ G  +  FE+LY++K GL +  A+  +N++KNRYKD+LPYD TR++++  D YINA+ + +EIP   ++  V KY+A+QGP+ HT   F  M+WE K  +++MLT L E+GR+KC +YWPD  E    ++G  ++ C++E C   +V RE  L  +    +F   HLQY+ WPDH VP    DFL F   +R+ R + ++P++VHCSAGIGRTGV+ITM+ AI  +E  Q    L IV+ +R+QRAM++Q+  QY+FVC AI+  Y +
Sbjct:  224 GAINQAKSASSQLCRKVIGGMVWNTDLRRSLSVEHLETKSLPSL----DQKMQLVVSRITPGSPADKCIPKLKEGDQIVLINGRDISEHTHDQVVMFIKASRESHTRELVLLVRR-----KVVRHLGKTKSEDDADFTFFPPSILPTCSEYGDTLQGSMEQLSKGLETGVVLIQFEQLYRKKPGLAIICARTGQNMDKNRYKDVLPYDATRVLLQGEDDYINASYVNMEIP---STNIVNKYVATQGPLPHTCEQFWQMVWEQKLSIIIMLTTLTERGRTKCQQYWPDPPEVT--EYGKFRVICKTEDCTIAYVFREMLLTNTETGNEFPIFHLQYVAWPDHGVPDDSSDFLEFATCVRKKRVA-NQPVLVHCSAGIGRTGVLITMETAICLIEQNQPVYPLDIVRQMRDQRAMMVQTSSQYKFVCEAILRVYKD 643
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Xenopus
Match: mon2 (MON2 homolog, regulator of endosome-to-Golgi trafficking [Source:Xenbase;Acc:XB-GENE-975876])

HSP 1 Score: 301.597 bits (771), Expect = 7.880e-88
Identity = 165/435 (37.93%), Postives = 262/435 (60.23%), Query Frame = 2 
Query: 1922 NALSNSTSTMTQSTDKLI-----DTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDS--LPP--LPRKNLVND-IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSD-YINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRLKKSNETRKF--THLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
             A++ + S  +Q   K+I     +TD R  +++  +++K   ++    D K  ++V+++ P + AD+C PKL EGDQI+ IN     E T+D++   IK++       ++ LV +      V  H     +E+D D    PP  LP  +   D ++ +++ L   L+ G  +  FE+LY++K GL +  A+  +N++KNRYKD+LPYD TR++++  D YINA+ + +EIP   ++  V KY+A+QGP+ HT   F  M+WE K  +++MLT L E+GR+KC +YWPD  E    ++G  ++ C++E C   +V RE  L  +    +F   HLQY+ WPDH VP    DFL F   +R+ R + ++P++VHCSAGIGRTGV+ITM+ AI  +E  Q    L IV+ +R+QRAM++Q+  QY+FVC AI+  Y +
Sbjct:  267 GAINQAKSASSQLCRKVIGGMVWNTDLRRSLSVEHLETKSLPSL----DQKMQLVVSRITPGSPADKCIPKLKEGDQIVLINGRDISEHTHDQVVMFIKASRESHTRELVLLVRR-----KVVRHLGKTKSEDDADFTFFPPSILPTCSEYGDTLQGSMEQLSKGLETGVVLIQFEQLYRKKPGLAIICARTGQNMDKNRYKDVLPYDATRVLLQGEDDYINASYVNMEIP---STNIVNKYVATQGPLPHTCEQFWQMVWEQKLSIIIMLTTLTERGRTKCQQYWPDPPEVT--EYGKFRVICKTEDCTIAYVFREMLLTNTETGNEFPIFHLQYVAWPDHGVPDDSSDFLEFATCVRKKRVA-NQPVLVHCSAGIGRTGVLITMETAICLIEQNQPVYPLDIVRQMRDQRAMMVQTSSQYKFVCEAILRVYKD 686
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Xenopus
Match: mon2 (MON2 homolog, regulator of endosome-to-Golgi trafficking [Source:Xenbase;Acc:XB-GENE-975876])

HSP 1 Score: 289.271 bits (739), Expect = 2.104e-82
Identity = 152/371 (40.97%), Postives = 229/371 (61.73%), Query Frame = 2 
Query: 2099 ADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDS--LPP--LPRKNLVND-IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSD-YINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRLKKSNETRKFT--HLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            AD+C PKL EGDQI+ IN     E T+D++   IK++       ++ LV +      V  H     +E+D D    PP  LP  +   D ++ +++ L   L+ G  +  FE+LY++K GL +  A+  +N++KNRYKD+LPYD TR++++  D YINA+ + +EIP   ++  V KY+A+QGP+ HT   F  M+WE K  +++MLT L E+GR+KC +YWPD  E    ++G  ++ C++E C   +V RE  L  +    +F   HLQY+ WPDH VP    DFL F   +R+ R + ++P++VHCSAGIGRTGV+ITM+ AI  +E  Q    L IV+ +R+QRAM++Q+  QY+FVC AI+  Y +
Sbjct:  449 ADKCIPKLKEGDQIVLINGRDISEHTHDQVVMFIKASRESHTRELVLLVRR-----KVVRHLGKTKSEDDADFTFFPPSILPTCSEYGDTLQGSMEQLSKGLETGVVLIQFEQLYRKKPGLAIICARTGQNMDKNRYKDVLPYDATRVLLQGEDDYINASYVNMEIP---STNIVNKYVATQGPLPHTCEQFWQMVWEQKLSIIIMLTTLTERGRTKCQQYWPDPPEVT--EYGKFRVICKTEDCTIAYVFREMLLTNTETGNEFPIFHLQYVAWPDHGVPDDSSDFLEFATCVRKKRVA-NQPVLVHCSAGIGRTGVLITMETAICLIEQNQPVYPLDIVRQMRDQRAMMVQTSSQYKFVCEAILRVYKD 808

HSP 2 Score: 94.3597 bits (233), Expect = 6.159e-19
Identity = 86/325 (26.46%), Postives = 145/325 (44.62%), Query Frame = 2 
Query:  197 SHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQ--------LFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ-LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            S +   V+ LD +   F ++ + TG   LD V + L + ER++FG+Q+ +D   L++  ++W++ NK +RKQ+K      +  FRVRF   +   +Q+  T  Q        +   I Q +F+  I     ++         SELGD++SS     ++    FIPDQ+  F S V +      GL   +AE  YIN A+ L  YG + ++ + L +  +  G+ + G+ VY    +  T   PW +I K+  K K F +               H +  Q   +             + F      A K  W + +E H+FF+ +
Sbjct:   27 SEVVCTVRFLDGSQHCFRVNKQDTGHTLLDMVYNYLNLKEREFFGLQHSED--SLDS--HRWIEPNKPIRKQLKGGFPC-SLLFRVRFFIPDPNTLQQDQTSVQDSVLYALTIMFYICQ-LFSQCIESGNILSRWF------SELGDHNSSVHVPGHLSNTSFIPDQDNDFLSKVEAC-----GLGQTEAESCYINIARTLEFYGIETHSGRDLHNLDLLIGIASGGVAVYRK--LICTSFYPWVNILKISFKRKKFFL---------------HQRQKQNECREQI----------VTFNMLNYRACKNVWRSCVEHHTFFQTR 307
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Xenopus
Match: mon2 (MON2 homolog, regulator of endosome-to-Golgi trafficking [Source:Xenbase;Acc:XB-GENE-975876])

HSP 1 Score: 289.656 bits (740), Expect = 3.151e-82
Identity = 152/371 (40.97%), Postives = 229/371 (61.73%), Query Frame = 2 
Query: 2099 ADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDS--LPP--LPRKNLVND-IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSD-YINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRLKKSNETRKFT--HLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            AD+C PKL EGDQI+ IN     E T+D++   IK++       ++ LV +      V  H     +E+D D    PP  LP  +   D ++ +++ L   L+ G  +  FE+LY++K GL +  A+  +N++KNRYKD+LPYD TR++++  D YINA+ + +EIP   ++  V KY+A+QGP+ HT   F  M+WE K  +++MLT L E+GR+KC +YWPD  E    ++G  ++ C++E C   +V RE  L  +    +F   HLQY+ WPDH VP    DFL F   +R+ R + ++P++VHCSAGIGRTGV+ITM+ AI  +E  Q    L IV+ +R+QRAM++Q+  QY+FVC AI+  Y +
Sbjct:  487 ADKCIPKLKEGDQIVLINGRDISEHTHDQVVMFIKASRESHTRELVLLVRR-----KVVRHLGKTKSEDDADFTFFPPSILPTCSEYGDTLQGSMEQLSKGLETGVVLIQFEQLYRKKPGLAIICARTGQNMDKNRYKDVLPYDATRVLLQGEDDYINASYVNMEIP---STNIVNKYVATQGPLPHTCEQFWQMVWEQKLSIIIMLTTLTERGRTKCQQYWPDPPEVT--EYGKFRVICKTEDCTIAYVFREMLLTNTETGNEFPIFHLQYVAWPDHGVPDDSSDFLEFATCVRKKRVA-NQPVLVHCSAGIGRTGVLITMETAICLIEQNQPVYPLDIVRQMRDQRAMMVQTSSQYKFVCEAILRVYKD 846

HSP 2 Score: 84.7297 bits (208), Expect = 6.413e-16
Identity = 80/324 (24.69%), Postives = 138/324 (42.59%), Query Frame = 2 
Query:  197 SHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQ--------LFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            S +   V+ LD +   F ++ + TG   LD V + L + ER++FG+Q+ +D   L++  ++W++ NK +RKQ+K      +  FRVRF   +   +Q+  T  Q        +   I Q +F+  I     ++         SELGD++SS     ++    FIPDQ+  F S V ++H +               T  +L+ YG +      +D  +  G+ + G+ VY    +  T   PW +I K+  K K F +               H +  Q   +             + F      A K  W + +E H+FF+ +
Sbjct:   27 SEVVCTVRFLDGSQHCFRVNKQDTGHTLLDMVYNYLNLKEREFFGLQHSED--SLDS--HRWIEPNKPIRKQLKGGFPC-SLLFRVRFFIPDPNTLQQDQTSVQDSVLYALTIMFYICQ-LFSQCIESGNILSRWF------SELGDHNSSVHVPGHLSNTSFIPDQDNDFLSKVEAWHYS---------------TGTKLNLYGINFVDLHNLD--LLIGIASGGVAVYRK--LICTSFYPWVNILKISFKRKKFFL---------------HQRQKQNECREQI----------VTFNMLNYRACKNVWRSCVEHHTFFQTR 294
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Mouse
Match: Ptpn4 (protein tyrosine phosphatase, non-receptor type 4 [Source:MGI Symbol;Acc:MGI:1099792])

HSP 1 Score: 334.724 bits (857), Expect = 9.040e-98
Identity = 178/410 (43.41%), Postives = 257/410 (62.68%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRPIDS-KYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPP-LPRKNLVND---IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRL--KKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            I  D  V I M+P ++ ++GF +KGG D K PVIV++V P T AD C P+L EGDQ++ IN     E T+D++   IK++   K    L L+V+P    +V E      +E D   +P   P  ++  D   +R ++  L + L  G+ +  F++LY++K G+TM+ AK  +NI+KNRY+DI PYD TR+++K N DYINAN I +EIP   +S+ + +YIA QGP+ HT  DF  M WE  S +VVMLT  +E+GR KC++YWP+  E+       Q+ C SE+    ++ R+  L  ++ NE+R+ T +QY  WPDH VP    DFL F+  +R  R+ + EPI+VHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  QY FVC AI+  Y
Sbjct:  510 IPHDNLVLIKMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCE-KHSGELVLLVRPNAVYDVVEEKLE--SEPDFQYIPEKAPLDSVHQDDHSLRESMIQLAEGLITGTVLAQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVLLKGNEDYINANYINMEIP---SSSIINQYIACQGPLPHTCKDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPSESSSYG-CYQVTCHSEEGNPAYIFRKMTLFNQEKNESRQLTQIQYTAWPDHGVPDDSSDFLDFVCHVRDQRAGKEEPIIVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVY 912

HSP 2 Score: 186.037 bits (471), Expect = 1.569e-47
Identity = 130/423 (30.73%), Postives = 202/423 (47.75%), Query Frame = 2 
Query:  146 KSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNR---------RNTPGGERQSIVSAETNRPTG 1384
            ++YNV A+E A ++  ++ +   + LLD T + F ++    G   LD V   L++ ERDYFG+Q  DD    +N   +WL  NK +RKQ+K   S     FRV+F  ++  ++QE YTRYQ F QIKQDI   ++SC  + A  LA  ++QSELGDY+ S     Y+ ++ FIP+Q   FE ++A  H+   GL P +AE  Y+N A+ L  YG +  Y     ++++  G+ + GI +Y +    NT++  W  I K+  K K F ++L                            +H+   + L F      A K  W   +E H+FFR+  P   ++         +F +     + GR  + + +   +     DR FAR PSK   R         RN+   +R    S  +  P G
Sbjct:   11 RTYNVRASELA-RDRQHTEVVCNILLLDNTVQAFRVNKHDQGQVLLDIVFKHLDLTERDYFGLQLADD--STDNP--RWLDPNKPIRKQLKRG-SPYNLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLSCPCNTAALLASFAVQSELGDYNQSENLAGYLSDYSFIPNQPQDFEKEIAKLHQQHVGLSPAEAEFNYLNAARTLELYGVEFHYARDQSNNEILIGVMSGGILIYKNRVRMNTFL--WLKIVKISFKCKQFFIQL-------------------------RKELHESRETLLGFNMVNYRACKTLWKACVEHHTFFRLDRPLPPQKNFFAH----YFTLGSKFRYCGRTEV-QSVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNSLSDDRLETQSLPSRSPPG 395
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Mouse
Match: Ptpn3 (protein tyrosine phosphatase, non-receptor type 3 [Source:MGI Symbol;Acc:MGI:105307])

HSP 1 Score: 316.235 bits (809), Expect = 3.312e-91
Identity = 160/394 (40.61%), Postives = 248/394 (62.94%), Query Frame = 2 
Query: 2015 DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEE--DEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGL-QIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            + ++GF +KGG D K P++V+++ P + AD C PKL EGDQI+ IN     E T+D++   IK++        L LV++ +   ++ E  S +   +   E   P  P     + +  +++ L+  L+ G+ +  FE+LY++K GL ++ AK  +N++KNRYKD+LPYD TR++++ N DYINA+ + +E+P +     V KYIA+QGP+ +T + F  ++W+ K  LVVMLT L E+GR+KC++YWPD  + +   HG+  I C++E C   +V RE  +   ++ E    THLQY+ WPDH VP    DFL F+K +R +R    EP +VHCSAGIGRTGV++TM+ A+  +E       L IV+ +R+QRAM++Q+  QY+FVC AI+  Y
Sbjct:  518 EGRFGFNLKGGVDQKMPLVVSRINPESPADTCMPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE-SHSRELALVIRRKAVRSLAEIRSEDELSQLFPEAMFPACPEGG--DSLEGSMELLKKGLESGTVLIQFEQLYRKKPGLAVSFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEMPAA---NLVNKYIATQGPLPNTCAQFWQVVWDQKLSLVVMLTTLTERGRTKCHQYWPDPPDIM--DHGIFHIQCQTEDCTIAYVSREMLVTNTETGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVKYVRSLRVD-GEPALVHCSAGIGRTGVLVTMETAMCLIERNLPVYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVY 902

HSP 2 Score: 147.132 bits (370), Expect = 2.713e-35
Identity = 99/322 (30.75%), Postives = 160/322 (49.69%), Query Frame = 2 
Query:  182 KELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ-LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            KE   S +   ++ LD   + F ++ +  G + LD     L + E++YFG+Q+   DD +++   +WL+ +K +RKQ+K      T +FRVR+   +   +Q+  TR+  F Q+K D+   +++C  + AV LA  ++QS  GD++SS     Y+ + +FIPDQN  F S V S H+   GLK  +AE  YIN A+ L  YG +L+  + L +  +  G+ + GI VY      + Y  PW +I K+  K K F +                    QR  +A+S          + F      + K  W + +E HSFF+ K
Sbjct:   22 KEKTRSEVICSIRFLDGLVQTFKVNKQDLGQSLLDMAYGHLGVTEKEYFGLQH--GDDPVDSP--RWLEASKPLRKQLKGGFPC-TLHFRVRYFIPDPNTLQQEQTRHLYFLQLKMDVCEGRLTCPLNSAVVLASYAVQSHFGDFNSSIHHPGYLADSQFIPDQNDDFLSKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHGGRDLHNLDLMIGIASAGIAVYRKYICTSFY--PWVNILKISFKRKKFFIH-------------------QRQKQAESR------EHIVAFNMLNYRSCKNLWKSCVEHHSFFQAK 311
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Mouse
Match: Ptpn12 (protein tyrosine phosphatase, non-receptor type 12 [Source:MGI Symbol;Acc:MGI:104673])

HSP 1 Score: 201.83 bits (512), Expect = 3.405e-53
Identity = 101/264 (38.26%), Postives = 151/264 (57.20%), Query Frame = 2 
Query: 2417 EKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVI------KNSDYINANIIK-VEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYL---EMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            EK+Y    G      +K EN+ KNRYKDILP+D +R+ +      ++SDYINAN IK V  PK+        Y+A+QGP+ +T  DF  MIWE    ++VM     E GR KC +YWP  GE        +I CE+E+    + +R   L+  NE+R+     Y+NWPDHDVP   D  L  + ++R+ +     PI +HCSAG GRTG +  +D   + L   ++ + F+V ++++++R QR   +Q+++QYE V RAI   +
Sbjct:   45 EKIYPTATG------EKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKA--------YVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCENEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLF 294
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Mouse
Match: Ptpn20 (protein tyrosine phosphatase, non-receptor type 20 [Source:MGI Symbol;Acc:MGI:1196295])

HSP 1 Score: 189.119 bits (479), Expect = 1.446e-51
Identity = 96/244 (39.34%), Postives = 147/244 (60.25%), Query Frame = 2 
Query: 2450 MNEAKKSENINKNRYKDILPYDQTRIVI-KNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWP-DQGETLKLQHGLQIFCESEKCIDTFVLREFRL--KKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAII 3169
             N     +N +KNRY+DILPYD TR+ + KN DYINA+ I++      N    + YIA+QGP+  T  DF  M+ EN   ++ M+T  +E G  KCY YWP    E L+ +H   +F E+      F +R F++  K + +++   HLQ+  WPDH  P   D F+ +++ +R  +S  + P++VHCSAG+GRTGV I +D+  S +E   SF +++IV  +R QR  +IQ+++QY+F C  I+
Sbjct:  181 FNSGNTLQNRDKNRYRDILPYDSTRVPLGKNKDYINASYIRI-----VNHEEEYFYIATQGPLPETIEDFWQMVLENNCNVIAMITREIECGVIKCYSYWPISLKEPLEFEH-FSVFLETFHVTQYFTVRVFQIVKKSTGKSQCVKHLQFTKWPDHGTPASADFFIKYVRYVR--KSHITGPLLVHCSAGVGRTGVFICVDVVFSAIEKNYSFDIMNIVTQMRKQRCGMIQTKEQYQF-CYEIV 415
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Mouse
Match: Ptpn22 (protein tyrosine phosphatase, non-receptor type 22 (lymphoid) [Source:MGI Symbol;Acc:MGI:107170])

HSP 1 Score: 189.504 bits (480), Expect = 1.749e-49
Identity = 104/259 (40.15%), Postives = 151/259 (58.30%), Query Frame = 2 
Query: 2426 YKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVI------KNSDYINANIIK-VEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLE---MKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAII 3169
            YK  +      A++ +NI KNRYKDILPYD + + +      ++S YINA+ IK V  PK+        YIA+QGP+  T  DF  MIWE +  ++VM     E G+ KC +YW + GET +LQ G   I CE+EK    + +R  + K +NETR      Y NWPDHDVP  +D  L  +  +R  +     PI +HCSAG GRTGV+  +D     L+   + ++FSV ++++++R QR  L+Q+Q+QYE V  A++
Sbjct:   38 YKADKIYPTTVAQRPKNIKKNRYKDILPYDHSLVELSLLTSDEDSSYINASFIKGVYGPKA--------YIATQGPLSTTLLDFWRMIWEYRILVIVMACMEFEMGKKKCERYWAEPGET-QLQFGPFSISCEAEKKKSDYKIRTLKAKFNNETRIIYQFHYKNWPDHDVPSSIDPILQLIWDMRCYQEDDCVPICIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQEQYELVYSAVL 287
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. UniProt/SwissProt
Match: sp|P29074|PTN4_HUMAN (Tyrosine-protein phosphatase non-receptor type 4 OS=Homo sapiens OX=9606 GN=PTPN4 PE=1 SV=1)

HSP 1 Score: 336.265 bits (861), Expect = 2.165e-97
Identity = 180/411 (43.80%), Postives = 258/411 (62.77%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPP-LPRKNLVND---IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGL-QIFCESEKCIDTFVLREFRL--KKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            I  D  V I M+P +  ++GF +KGG D K PVIV++V P T AD C P+L EGDQ++ IN     E T+D++   IK++   +    L L+V+P    +V E    N  E D   +P   P  ++  D   +R ++  L + L  G+ +  F++LY++K G+TM+ AK  +NI+KNRY+DI PYD TR+++K N DYINAN I +EIP   +S+ + +YIA QGP+ HT +DF  M WE  S +VVMLT  +E+GR KC++YWP+   T    +G  Q+ C SE+    ++ R+  L  ++ NE+R  T +QYI WPDH VP    DFL F+  +R  R+ + EP+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  QY FVC AI+  Y
Sbjct:  510 IPHDNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCE-RHSGELMLLVRPNAVYDVVEEKLEN--EPDFQYIPEKAPLDSVHQDDHSLRESMIQLAEGLITGTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGNEDYINANYINMEIP---SSSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPE--PTGSSSYGCYQVTCHSEEGNTAYIFRKMTLFNQEKNESRPLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKRAGKEEPVVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVY 912

HSP 2 Score: 187.963 bits (476), Expect = 2.429e-47
Identity = 124/395 (31.39%), Postives = 195/395 (49.37%), Query Frame = 2 
Query:  143 NKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRR 1324
             ++YNV A+E A ++  ++ +   + LLD T + F ++    G   LD V   L++ E+DYFG+Q  DD    +N   +WL  NK +RKQ+K   S  +  FRV+F  ++  ++QE YTRYQ F QIKQDI   ++ C  + A  LA  ++QSELGDY  S   + Y+ ++ FIP+Q   FE ++A  H+   GL P +AE  Y+NTA+ L  YG +  Y     ++++  G+ + GI +Y +    NT+  PW  I K+  K K F ++L                            +H+   + L F      A K  W   +E H+FFR+  P   ++         +F +     + GR  + + +   +     DR FAR PSK   R+
Sbjct:   10 GRTYNVRASELA-RDRQHTEVVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADD--STDNP--RWLDPNKPIRKQLKRG-SPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVRMNTF--PWLKIVKISFKCKQFFIQL-------------------------RKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRLDRPLPPQKNFFAH----YFTLGSKFRYCGRTEV-QSVQYGKEKANKDRVFARSPSKPLARK 366
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. UniProt/SwissProt
Match: sp|Q9WU22|PTN4_MOUSE (Tyrosine-protein phosphatase non-receptor type 4 OS=Mus musculus OX=10090 GN=Ptpn4 PE=1 SV=2)

HSP 1 Score: 334.724 bits (857), Expect = 6.324e-97
Identity = 178/410 (43.41%), Postives = 257/410 (62.68%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRPIDS-KYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPP-LPRKNLVND---IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRL--KKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            I  D  V I M+P ++ ++GF +KGG D K PVIV++V P T AD C P+L EGDQ++ IN     E T+D++   IK++   K    L L+V+P    +V E      +E D   +P   P  ++  D   +R ++  L + L  G+ +  F++LY++K G+TM+ AK  +NI+KNRY+DI PYD TR+++K N DYINAN I +EIP   +S+ + +YIA QGP+ HT  DF  M WE  S +VVMLT  +E+GR KC++YWP+  E+       Q+ C SE+    ++ R+  L  ++ NE+R+ T +QY  WPDH VP    DFL F+  +R  R+ + EPI+VHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  QY FVC AI+  Y
Sbjct:  510 IPHDNLVLIKMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCE-KHSGELVLLVRPNAVYDVVEEKLE--SEPDFQYIPEKAPLDSVHQDDHSLRESMIQLAEGLITGTVLAQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVLLKGNEDYINANYINMEIP---SSSIINQYIACQGPLPHTCKDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPSESSSYG-CYQVTCHSEEGNPAYIFRKMTLFNQEKNESRQLTQIQYTAWPDHGVPDDSSDFLDFVCHVRDQRAGKEEPIIVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVY 912

HSP 2 Score: 186.037 bits (471), Expect = 1.098e-46
Identity = 130/423 (30.73%), Postives = 202/423 (47.75%), Query Frame = 2 
Query:  146 KSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNR---------RNTPGGERQSIVSAETNRPTG 1384
            ++YNV A+E A ++  ++ +   + LLD T + F ++    G   LD V   L++ ERDYFG+Q  DD    +N   +WL  NK +RKQ+K   S     FRV+F  ++  ++QE YTRYQ F QIKQDI   ++SC  + A  LA  ++QSELGDY+ S     Y+ ++ FIP+Q   FE ++A  H+   GL P +AE  Y+N A+ L  YG +  Y     ++++  G+ + GI +Y +    NT++  W  I K+  K K F ++L                            +H+   + L F      A K  W   +E H+FFR+  P   ++         +F +     + GR  + + +   +     DR FAR PSK   R         RN+   +R    S  +  P G
Sbjct:   11 RTYNVRASELA-RDRQHTEVVCNILLLDNTVQAFRVNKHDQGQVLLDIVFKHLDLTERDYFGLQLADD--STDNP--RWLDPNKPIRKQLKRG-SPYNLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLSCPCNTAALLASFAVQSELGDYNQSENLAGYLSDYSFIPNQPQDFEKEIAKLHQQHVGLSPAEAEFNYLNAARTLELYGVEFHYARDQSNNEILIGVMSGGILIYKNRVRMNTFL--WLKIVKISFKCKQFFIQL-------------------------RKELHESRETLLGFNMVNYRACKTLWKACVEHHTFFRLDRPLPPQKNFFAH----YFTLGSKFRYCGRTEV-QSVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNSLSDDRLETQSLPSRSPPG 395
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. UniProt/SwissProt
Match: sp|P26045|PTN3_HUMAN (Tyrosine-protein phosphatase non-receptor type 3 OS=Homo sapiens OX=9606 GN=PTPN3 PE=1 SV=2)

HSP 1 Score: 323.939 bits (829), Expect = 3.498e-93
Identity = 163/393 (41.48%), Postives = 243/393 (61.83%), Query Frame = 2 
Query: 2015 DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEE--DEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            D K+GF +KGG D K P++V+++ P + AD C PKL EGDQI+ IN     E T+D++   IK++        L LV++ R   +  +  S +   +   E   P  P     + +  ++  L+  L+ G+ +  FE+LY++K GL +  AK  +N++KNRYKD+LPYD TR++++ N DYINA+ + +EIP +     V KYIA+QGP+ HT + F  ++W+ K  L+VMLT L E+GR+KC++YWPD  + +    G  I C+SE C   +V RE  +   ++ E    THLQY+ WPDH VP    DFL F+  +R +R   SEP++VHCSAGIGRTGV++TM+ A+   E       L IV+ +R+QRAM++Q+  QY+FVC AI+  Y
Sbjct:  518 DGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE-SHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGG--DTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAA---NLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMN-HGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVD-SEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVY 902

HSP 2 Score: 155.221 bits (391), Expect = 4.836e-37
Identity = 102/322 (31.68%), Postives = 162/322 (50.31%), Query Frame = 2 
Query:  182 KELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ-LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            KE   S +   +  LD   + F ++ + TG   LD V + L + E++YFG+Q+  DDD +++   +WL+ +K +RKQ+K      T +FRVRF   +   +Q+  TR+  F Q+K DI   +++C  + AV LA  ++QS  GDY+SS     Y+ +  FIPDQN  F + V S H+   GLK  +AE  YIN A+ L  YG +L++ + L +  +  G+ + G+ VY      + Y  PW +I K+  K K F +                    QR  +A+S          + F      + K  W + +E H+FF+ K
Sbjct:   22 KEKTRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQH--DDDSVDSP--RWLEASKAIRKQLKGGFPC-TLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFY--PWVNILKISFKRKKFFIH-------------------QRQKQAESR------EHIVAFNMLNYRSCKNLWKSCVEHHTFFQAK 311
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. UniProt/SwissProt
Match: sp|P28191|PTP1_CAEEL (Tyrosine-protein phosphatase 1 OS=Caenorhabditis elegans OX=6239 GN=ptp-1 PE=2 SV=3)

HSP 1 Score: 326.25 bits (835), Expect = 3.908e-93
Identity = 170/415 (40.96%), Postives = 251/415 (60.48%), Query Frame = 2 
Query: 1973 IDTDTRVEIAMRP-IDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRK---NLVNDIRLT--IKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREF--RLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            +  D  V I MRP    ++GF +KGG D   PVIV++V P ++AD+C P+L EGDQ++ I+      +++D + + I+S  S      L+L ++P +Y   +E       +E + ++ P P +   ++ N  +L+  ++ L DSL  G  V  FE LY++K G++MN  + + N+ KNRY+D+ PYD TR+ ++ S   DYINAN + +EIP   +S  V +YIA QGP+ HTSSDF  M+WE     +VMLT + E+GR KC++YWP   ET +    L I C  +K       REF  R + S+E R+ T +QYI WPDH VP     F+ F+  +R+ R    +PIVVHCSAGIGRTGV+I M+ A   +E  +    L IV+ +R+QRAMLIQ+  QY FVC +I+  Y++
Sbjct:  610 VGEDQVVTIKMRPDRHGRFGFNVKGGADQNYPVIVSRVAPGSSADKCQPRLNEGDQVLFIDGRDVSTMSHDHVVQFIRSARSGLNGGELHLTIRPNVYRLGEE------VDEPDSTMVPEPARVADSVPNSDKLSKSLQLLADSLNSGKVVDHFEMLYRKKPGMSMNICRLTANLAKNRYRDVCPYDDTRVTLQASPSGDYINANYVNMEIP---SSGIVNRYIACQGPLAHTSSDFWVMVWEQHCTTIVMLTTITERGRVKCHQYWPRVFETQEYGR-LMIKCIKDKQTTNCCYREFSIRDRNSSEERRVTQMQYIAWPDHGVPDDPKHFIQFVDEVRKARQGSVDPIVVHCSAGIGRTGVLILMETAACLVESNEPVYPLDIVRTMRDQRAMLIQTPGQYTFVCESILRAYHD 1014

HSP 2 Score: 130.954 bits (328), Expect = 2.482e-29
Identity = 111/393 (28.24%), Postives = 181/393 (46.06%), Query Frame = 2 
Query:  203 IKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTN-----YVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDD-QVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSIVSA 1363
            I+  V  LD TS  F +   + G   L+ V + LEI+E+DYFG+ +   D+       KWL  +K +RKQ+         +FRV+F   +  ++++ +TR+Q +QQ++Q++   ++ C++     LA   +Q+E+GD+   T   +     Y  +F  +PD    F   VA  H+   G  P+ AE  +++ A++L  YG D+Y     +   ++ G+ A GI V++     N Y   W  I K+  K K F V       +VA  DG           +++ +I   MS+ +          K  W   IE H+FFR+K P +  +       +  F       +SGR     L +   R     R+F R  SK    R+T  G  QSI S+
Sbjct:   29 IRCTVTFLDSTSYHFEIEKNSLGIVLLEKVFNYLEIIEKDYFGLVFIAVDNSSAQQ-KKWLDPSKNLRKQMI--CPPYHLFFRVKFYVRDPNRLRDEFTRFQFYQQVRQNLEEGRLPCNEGSLALLASYVVQAEVGDFEEKTHGMSRTCLCYKIQFATLPDD---FSDRVAELHQLHIGQTPDVAEQNFLDHARRLEMYGMDVYDGVDANHLPIEIGVGAVGIKVFHEGIKMNEYA--WVRIRKLSFKKKQFQV-------LVANEDG----------VSETIMIFNIMSAKI---------CKLLWKCCIEQHTFFRLKTPPKTPQ-------RKVFNFGSKFRYSGRTEYQTLEENEHRKSAGHRNFHRSLSKSSFLRSTFSGNTQSIDSS 380
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. UniProt/SwissProt
Match: sp|A2ALK8|PTN3_MOUSE (Tyrosine-protein phosphatase non-receptor type 3 OS=Mus musculus OX=10090 GN=Ptpn3 PE=1 SV=1)

HSP 1 Score: 316.235 bits (809), Expect = 2.317e-90
Identity = 160/394 (40.61%), Postives = 248/394 (62.94%), Query Frame = 2 
Query: 2015 DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEE--DEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGL-QIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            + ++GF +KGG D K P++V+++ P + AD C PKL EGDQI+ IN     E T+D++   IK++        L LV++ +   ++ E  S +   +   E   P  P     + +  +++ L+  L+ G+ +  FE+LY++K GL ++ AK  +N++KNRYKD+LPYD TR++++ N DYINA+ + +E+P +     V KYIA+QGP+ +T + F  ++W+ K  LVVMLT L E+GR+KC++YWPD  + +   HG+  I C++E C   +V RE  +   ++ E    THLQY+ WPDH VP    DFL F+K +R +R    EP +VHCSAGIGRTGV++TM+ A+  +E       L IV+ +R+QRAM++Q+  QY+FVC AI+  Y
Sbjct:  518 EGRFGFNLKGGVDQKMPLVVSRINPESPADTCMPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE-SHSRELALVIRRKAVRSLAEIRSEDELSQLFPEAMFPACPEGG--DSLEGSMELLKKGLESGTVLIQFEQLYRKKPGLAVSFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEMPAA---NLVNKYIATQGPLPNTCAQFWQVVWDQKLSLVVMLTTLTERGRTKCHQYWPDPPDIM--DHGIFHIQCQTEDCTIAYVSREMLVTNTETGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVKYVRSLRVD-GEPALVHCSAGIGRTGVLVTMETAMCLIERNLPVYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVY 902

HSP 2 Score: 147.132 bits (370), Expect = 1.897e-34
Identity = 99/322 (30.75%), Postives = 160/322 (49.69%), Query Frame = 2 
Query:  182 KELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ-LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVK 1144
            KE   S +   ++ LD   + F ++ +  G + LD     L + E++YFG+Q+   DD +++   +WL+ +K +RKQ+K      T +FRVR+   +   +Q+  TR+  F Q+K D+   +++C  + AV LA  ++QS  GD++SS     Y+ + +FIPDQN  F S V S H+   GLK  +AE  YIN A+ L  YG +L+  + L +  +  G+ + GI VY      + Y  PW +I K+  K K F +                    QR  +A+S          + F      + K  W + +E HSFF+ K
Sbjct:   22 KEKTRSEVICSIRFLDGLVQTFKVNKQDLGQSLLDMAYGHLGVTEKEYFGLQH--GDDPVDSP--RWLEASKPLRKQLKGGFPC-TLHFRVRYFIPDPNTLQQEQTRHLYFLQLKMDVCEGRLTCPLNSAVVLASYAVQSHFGDFNSSIHHPGYLADSQFIPDQNDDFLSKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHGGRDLHNLDLMIGIASAGIAVYRKYICTSFY--PWVNILKISFKRKKFFIH-------------------QRQKQAESR------EHIVAFNMLNYRSCKNLWKSCVEHHSFFQAK 311
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. TrEMBL
Match: A0A498ND05 (Tyrosine-protein phosphatase OS=Labeo rohita OX=84645 GN=ROHU_018745 PE=3 SV=1)

HSP 1 Score: 501.13 bits (1289), Expect = 1.761e-155
Identity = 354/1060 (33.40%), Postives = 523/1060 (49.34%), Query Frame = 2 
Query:  143 NKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDD-DKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNR------------RNTPGGERQSIVSAETNRPTGIVYGKSNPTSNNPSNYVKPKLNDKKKTXXXXXXXXXXXXXXXXXXXXPGAFRNKSSVTQSVRVPKASTAKGFQKHPVIHSSMPRQKVTGTISKSQT---SINQELTPTDP-----NIPD-------------IMSRSIGRNEQNKPGNNVSLKEQNILFETKMKTSKSPKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNSTSTMTQSTDK-----LIDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLP---PLPRKNLVNDI-RLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSD-YINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
             +SYNV A E A ++   + +   V LLD T + F ++    G   LD+V   LE+ ERDYFG+   DD  D L     +WL  NK +RKQ+K   S     FRV+F  ++  ++QE YTRYQ F QIKQDI + ++ C  + A  LA  ++QSELGDY+ +     Y+ EF FIP+Q   FE +V   H+   GL P  +E  Y+NTA+ L  YG +L Y     + ++  G+ + GI +Y +  ++  Y  PW  I K+  K K F ++L                             H+   + L F      A K  W   +E H+FFR+  P   ++         +F +     + GR T  + +   +   + DR FAR PSK   R            RN+   ER    S  T  P G            P++Y K  +N                             RN   V +  R+ + S+      H VIH+S      +   S S T   SI+ E TP  P     N P+               S S+G    +  G   +   + +        +  PK SR ++ +L            LS S   + N + N    +  +TDK     +I  D  V I M+P +  ++GF +KGG D K P+IV++V P T+AD C P+L EGDQ++ IN     E T+D++   IK++       ++ LV    +Y  V+E      TE D   +P   P     L  D  R ++  L+D L   + +  F++LY+++ G+TM+ AK  +NI+KNRY+DI PYD TR+++K +D YINAN I +EIP S   + + +YIA QGP+ +T  DF  M WE  S LVVMLT  +E+GR KC++YWP+   +     G Q+ C++E+    F++R+  L   +S ETR+ T +QY+ WPDH VP    DFL F+ ++R  R+ + EP+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  Q++FVC AI+  Y
Sbjct:   10 GRSYNVRATELA-RDRQRTEVVCNVLLLDNTVQPFKVNKHDQGQILLDAVFKHLELTERDYFGLHLADDSSDSL-----RWLDPNKPIRKQLKRG-SPHHLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILSGRLPCPHNTAALLASYAVQSELGDYNEAENLPGYLSEFCFIPNQPQGFEKEVTKHHQQHSGLTPAQSEFNYLNTARTLELYGVELHYARDQSNTEIFIGVMSAGIAIYKN-RVRINYF-PWLKIVKISFKCKQFFIQL-------------------------RKEAHETRDTLLGFNMVNYRACKNLWKACVEHHTFFRLDRPVPPQKNFFAH----YFNLGSRFRYCGR-TEAQSVQYGKEKGIKDRVFARSPSKPLGRKFMGVTDWESVSRNSLSEERLETRSLPTRSPPG-----------TPNHYYKCSVNS----------------------------RNSLFVQEGPRL-RPSSMGHLVDH-VIHASPSLPVFSNHKSASSTQANSISLESTPYHPLSAPLNGPEWKLNARCAAVKCVYRSHSVGHRALDFNG---AWSPEGV---EGPPPALPPKQSRKNLSQLI-----------LSHSQQDLDNHI-NEMYDVPIATDKATPNGVIPHDNLVLIKMKPDENGRFGFNVKGGSDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGRDIAEHTHDQVVMFIKASCESHSGELILLVRPNAIYDVVEEKLE---TEPDFQYIPEKSPTDPSQLDQDAWRDSMLQLKDGLNSATVLAQFDQLYRKRPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGTDDYINANYINMEIPAS---SLINRYIACQGPLPNTCPDFWQMTWEQGSSLVVMLTTQVERGRVKCHQYWPNPSGSATYG-GFQVCCQTEEGNSAFLVRDMTLNHIESGETRELTQIQYLAWPDHGVPDDSTDFLDFVALVRSKRAGKDEPVVVHCSAGIGRTGVLITMETAMCLMECGQPVYPLEIVRTMRDQRAMMIQTPSQFKFVCEAILKVY 964
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. TrEMBL
Match: A0A1D1VE90 (Uncharacterized protein OS=Ramazzottius varieornatus OX=947166 GN=RvY_10243 PE=4 SV=1)

HSP 1 Score: 489.574 bits (1259), Expect = 5.995e-151
Identity = 335/1013 (33.07%), Postives = 501/1013 (49.46%), Query Frame = 2 
Query:  215 VKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTF--YKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDD-QVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSIVSAETNRPTGIVYGKSNPTS---NNPSNYVKPKLNDKKKTXXXXXXXXXXXXXXXXXXXXPGAFR--NKSSVTQSVRV---PKASTAKGFQKHPVIHSSMPRQKVTGTISKSQTSINQELTPTDP-----NIPDIMSRSIGRNEQNKPGNNVSLKEQNILFETKMKTSKSPKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKN----SDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRL--KKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            V  LD  +  F++   A G   +D V D L+++ERDYFG+Q+ + + ++      ++WL+ +K ++KQ+K   S    YFRV+F  +    + + +TRY  F Q+K+DI   K+S  + +A  LA   +QSELGD+     K  Y+ E++F+P+Q   F+  V   HK  +G  P DAE  +++  K+L  YG  LY  Q  +   +Q G+   G  V+   +     + PW  I K+  K K F +++             H +S             +   + L F   +    K  W + +E HSFFR+   + +        S+    +S  +   GR     L +  RR R    S +R PSKRY RR   G  R  I+  E   P  IV+ K    S   NN +  +    +  ++  +   +     +         G  R  NK  V+    +   P  S  +G    P       +    G   ++     +  + T P     N  + +    G N    P N +S +        ++ T         S   L S+   T+P  +L     S  N LS S+ T  +     I  D+         D K+GF ++GG D   PVIVT+V PNT AD   P+L EGDQ++ IN      LT+DE+  +IKS+   +   ++ L V+P +Y   DE         D    P  P  +  N ++ +I  L D LK  +A+  FE+LY++   ++M +A+   N  +NRYKD+LPYD TR+ +++    SDYINAN +K+EIP    S  V +YIA+QGP+ HT SDF  MIWE +S LVVMLT L+E+GR KC++YWP+  ET   ++G LQ+ C  E+  D F  RE  L   ++NE R  TH+QYI WPDH VP    DFL F+  +RQ R    EP V+HCSAGIGRTGV+I M+ A+  +E  +    L IV+ +R+QRAMLIQ+  QY+FVC AI+  +N+
Sbjct:   39 VHFLDGETHTFHIDKHAKGQYLIDLVLDHLDLVERDYFGLQFLEPEYEIAQDLIIWRWLEPHKSLKKQLKGG-SPYVLYFRVKFYVSNPCLLHDEFTRYTYFLQLKKDIQEGKLSVPQSMASLLASYVIQSELGDFDPDEHKPGYLSEYKFVPEQGPNFDVKVHELHKQHRGETPADAEYNFLDHCKRLDTYGISLYHAQDANGVDIQLGVTYSGFVVFQ--NATRLSVFPWTKIIKISFKQKQFFIQI-------------HEES-------------KDYDTLLGFYMLSVRTCKYLWKSCVEHHSFFRMNSTRPLL-------SRKLSLLSWGSKLRGRTEYKTLEEGTRRYRNDKPSISRSPSKRY-RRTIAGSSRNEILQ-EKQAP--IVHDKERNGSVIRNNNNVTIVHVGSQPQQVYQQTNNGHLHLNGSVAAANTNGTLRQSNKGFVSNGTTLILPPNHSVKRGL---PSSSGDGIKTDDDGGFREAPALYARSSSSTAPAKYASNAANHVRLDAGENATPYPVNGLSYRT----MPERIPTGAVDTTVMTSPVHLVSSSNVTRPRKELVLPSDSNGNGLSLSSLTCIR-----IKPDS---------DGKFGFNVRGGIDLNLPVIVTRVAPNTPADLAVPRLHEGDQVLSINGRETATLTHDEVVILIKSSRETRSGELV-LYVRPNIYNGGDEQEPEFQYIPDT---PRAPNGHSGNPLQESILLLADGLKTNNAMLHFEQLYRKNPKMSMKDAEMPMNNARNRYKDVLPYDATRVFLQHNESGSDYINANFVKMEIP---TSGIVNRYIAAQGPLPHTGSDFWQMIWEQQSTLVVMLTSLVEQGRIKCHQYWPNLYETS--EYGPLQVTCMKEQAQDCFAFRELSLIHTETNEERHITHMQYIAWPDHGVPDDASDFLEFVIRVRQHRVGMGEPTVIHCSAGIGRTGVLILMETAMCLIEANEPVYPLDIVRTMRDQRAMLIQTTSQYKFVCEAILRVFND 981
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. TrEMBL
Match: A0A085M4E3 (Uncharacterized protein OS=Trichuris suis OX=68888 GN=M513_07071 PE=4 SV=1)

HSP 1 Score: 474.167 bits (1219), Expect = 6.037e-145
Identity = 329/1058 (31.10%), Postives = 526/1058 (49.72%), Query Frame = 2 
Query:  149 SYNVAAAERANKELLYSH--IKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQ--LMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSIVSAETNRPTGIVYGKSNPTSNNP---SNYVKPKLNDKKKTXXXXXXXXXXXXXXXXXXXXPGAFRNKSSVTQSVRVPKASTAKGFQKHPV-----------------IHSSMPRQKVTGTISKSQTSINQELTPTDPN-IPDIMSRSIGRNEQNKPGNNVSLKEQNILFETKMKTSKSPKASRYSIQELKSNKAST--------QPNAKLS------GSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRP-IDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVD-EHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRL--KKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYN 3181
            +YNV  +E     +   H  I   V  LD T  +F +   A G   L+ V D LE++E+DYFG+Q+ D     +    +WL+  K +RKQ++    +   +FRV+F  ++  ++ E YTRY  + Q+++DI + ++ CS+   + LA  ++QSELGD+++   +  Y+  F F P+Q       VA  H+  +G  P DAE  +++ AK+L  YG DLY  +   M D VQ G+ + G+ ++       T+I  W+ I K+  K K F ++L                      +A+SS   Q       F   +  ++K  W + IE H+FFR+  P           +++ F       +SGR     L ++++R R+  ++F R+ S     R+T       I S+   R   +  G  +P SN P   S  V  KL        +    +S  +     E+ P    + SS   +V V K+      +K PV                 +  S    ++ G +  S  S + + +   PN +P I S    +N ++   +    +   +L   + + +  P   + ++       AST        +P+ +        G  S+  N    ST+            DT V I MRP    ++GF +KGG D   P+IV++V P + AD C P+L EGDQ++ IN     + T++++   I+S        +L L+V+P  Y+  D E    +   +       +PR ++   +R ++  L+DSL  GSA+  F+KLY++   +TMN AK  EN++KNRY+DI PYD+TR+VI+N    DYINA+ + +EIP    S  V +YIA+QGP+ HT++DF  ++WE     VVMLT  +E+GR KC++YWP+  ET   QHG L+I C  E       +RE  +   ++ E R  +H+QY  WPDH VP    + + F+  +R+ R+   EP++VHCSAGIGRTGV+I ++ A+  +E  +    L IVK +R+QRAMLIQ+  QY+F C AI+  Y+
Sbjct:    8 TYNVRESEMTGDSIRIPHRPILCDVHFLDGTQRVFEVEKHALGQELLERVYDHLELIEKDYFGLQFTDLSP--DPGAMRWLEPAKSIRKQMQCPPYI--LHFRVKFYVSDPSKLLEEYTRYHFYLQLRKDIADGRLICSESSVIVLASYAVQSELGDHNTEEHREAYLETFHFAPNQTPAIMRKVAELHRQHRGQTPADAEYNFLDHAKRLDFYGVDLYRAKDSSMSD-VQLGVASFGVGIFQRAVKTKTFI--WSRIMKLSFKRKQFFIQL--------------------KSEANSSEAVQC------FTLSSTRSSKMLWKSCIEHHTFFRLISPPAPS-------AKALFTFGSQFRYSGRTEHQTLEEMKKRARI-GKTFCRLSSSNCFARST-------IASSPYARSQEL--GAGSPASNCPLPSSCSVARKLKPTTSVDAAAAGAASHRTASSLSELVP----SPSSSDGNVVVGKSDNPSPCRKMPVETTFGLMDTTAVDNDGVVEQSY---ELPGIVHGSDGSTSGQSSRAVPNSLPVIYSIKEQKNLRSSLRHTCHQRVSALLLHHRQQGAGRPVDFKDALIYQHCTGASTSTASPVVCRPSGRYGSMLASPGQSSTAGNGCPTSTALFNGFHSSFAGDDTLVTIRMRPDSQGRFGFNVKGGWDQNYPIIVSRVIPGSPADTCLPRLNEGDQVLAINRVEVSQCTHEQVVRYIRSCKETASKELL-LIVRPNAYIGEDIEEPDQHYVPQTPHVADCVPRPDI---LRQSLILLKDSLASGSALLYFDKLYRKSPLMTMNIAKYPENVSKNRYRDISPYDKTRVVIQNGNCGDYINASFVNMEIP---TSGIVNRYIAAQGPLPHTTTDFWQVVWEQLCHTVVMLTATVERGRVKCHQYWPNLYETQ--QHGRLEITCVKESETYVGAIRELSVICSETKEERLISHMQYSAWPDHGVPDDPRELIDFIVDVRRSRTGMVEPVLVHCSAGIGRTGVLILLETAMCLIEASEPIYPLEIVKSMRDQRAMLIQNAAQYKFACEAILKIYH 999
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. TrEMBL
Match: A0A2A2LK82 (Uncharacterized protein OS=Diploscapter pachys OX=2018661 GN=WR25_22752 PE=4 SV=1)

HSP 1 Score: 461.84 bits (1187), Expect = 1.908e-140
Identity = 311/1049 (29.65%), Postives = 500/1049 (47.66%), Query Frame = 2 
Query:  149 SYNVAAAERANKELLYSH----IKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQ-VQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSIVSAETNRPTGIVYGKSNP--TSNNPSNYVKPKLNDKKKTXXXXXXXXXXXXXXXXXXXXPGAFRNKSSVTQSVRVPKASTAKGFQKHPVIHSSMPRQKVTGTISKSQTSINQELTPTDP----------------NIPDIMSRSIG-------RNEQNKPGNNVSLKEQNILFETKMKTSKSPKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPIDS-KYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYL--NVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKN---SDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRLKK--SNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            SY+V  +E  N +LL +     I   +  LD T + F ++  A G   LD V   LE++ERD+FG+Q+    D    T  +WL   K VRKQ+         +FRV+F  ++  ++ E YTRY  + Q++ DI   ++ C+      LA  ++QSELGDY++      Y+ E +F P Q A F   V   H   +   P +AE  +++ AK+L  YG +L   +      V  G+N++GI V++     N +  PW++I K+  K K F +++ LS                            +  + + F   +    KE W   +E H+FFR+  P  +        S+  F I     +SGR     + ++++R RL DR+F R  SK    R T GG    + SA  +         ++P  +S   S    P L  ++   +      S++    +    P A    ++         A+     +      +S  R+ +      S +S      P+                  N    +SRSIG       R   ++P           +       + SP++S  S     S    + P ++                S  +Q ++  +  D+ V + MRP  + ++GF +KGG D   PVIV++V   ++AD+C P+L EGD ++ IN     ++++D++   I+S  +      L L +KP +Y   +V +        E       +PR +++     ++K + D+LK G A+  FE LY++   ++ N+  + +NI KNRY+DI PYD TR+++ +    DYINAN + +EIP   +S  V +YIA QGP+ HT+ DF  M+WE     +VMLT   E GR+KC++YWP   E  +  +G L + C  E+   T V REF +K    NE R+ T +QY+ WPDH  P    +F++F++ +R+ R    EPIVVHCSAGIGRTGV+I M+ A   +E  +    L +V+ +R+QRAML+Q+  QY+FVC +I+  Y
Sbjct:    7 SYDVRQSEGLNPDLLLASPSRTITCTITFLDATEKQFVINRHALGKELLDKVFTHLELVERDFFGLQFLCVVDS-RETQKRWLDPRKSVRKQML--CPPYQLFFRVKFYVSDPSKLIEEYTRYHFYLQVRSDILEGRLPCADGSLALLASYAVQSELGDYNAIEHAPGYLNELKFAPKQPADFAKRVEELHAMHRRQTPAEAEYNFLDHAKRLDLYGIELREARDRTGMLVGLGVNSYGIVVFHEGIKVNEF--PWSNIMKLSFKRKQFFIQVRLSD--------------------------DQTDAVVTFTMNSPPICKEYWKTCVENHTFFRLIAPPVVS-------SKGIFNIGSRYRYSGRTEFQTMEEVKQRARL-DRTFQRSHSKSSFMRATFGG----VPSASLDSSRAFTPSSASPDISSRILSESSAPSL--RRHAAKETTFGVSEDESADERSWTPAASLTVANSNMQACTSTATAPVHHRPPSAAQTSAGRKSIPNGYGHSSSSAGNSYHPSSSHSNGYGVYSVSQNGYVNGNGTLSRSIGGTVRMSTRAPHSQPHTYNHGNHTATVTAQSQPVAASPRSSVASFSSHASVNGGSPPRSR---------------RSPQSQKSNSPVSEDSVVTVRMRPDSAGRFGFNVKGGADQHYPVIVSRVAAGSSADKCHPRLNEGDMVLMINGRDVSKMSHDQVVSFIRSARTAPLGGELVLTIKPNVYRLGDVIDEPEPTAVPESARVAETVPRSDMLEQ---SLKLISDALKTGKALPQFEMLYRRNPRMSTNDCIQQQNIKKNRYRDICPYDATRVILTSCPTGDYINANYVNMEIP---SSGIVNRYIACQGPLNHTTEDFWIMVWEQLCSTIVMLTTTAENGRAKCHQYWPRLYE--QADYGKLSVRCLKERDTQTCVYREFSVKNRMKNEERRVTQMQYLAWPDHGTPNDPKEFISFVEEVRRARVGSVEPIVVHCSAGIGRTGVLILMETAACMIEANEPVYPLELVRIMRDQRAMLVQTPGQYQFVCESILKAY 987
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. TrEMBL
Match: A0A1B0AE30 (Tyrosine-protein phosphatase OS=Glossina pallidipes OX=7398 PE=3 SV=1)

HSP 1 Score: 408.683 bits (1049), Expect = 6.651e-121
Identity = 316/1092 (28.94%), Postives = 492/1092 (45.05%), Query Frame = 2 
Query:  209 VKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKT----DISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLY---------TCQLM--------------DDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMF--SGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSIVSAETNRPTGIVYGKSNPTSNNPSNYVKPKLNDKKKTXXXXXXXXXXXXXXXXXXXXPGAFRNKSSVTQSVRVPKASTAKGFQKHPVIHSSMPRQKVTGTISKSQTSINQELTPTDPNIPDIMSRSIGRNEQNKPGNNVSLKEQNILFETKMKTSKSPKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLP-------RKNLVNDIRLTIKSL---EDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDT--FVLREFRL--KKSNETRKFTHLQYINWPDHDV---PIKMDDFLAFMKMIR-------------QIR----------------------------------------SSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            V V  LD+T+  F +   A G + L+ V   LE+ ERDYFG+ +      +     +W+   KL +KQ       + S+    FRV+F  ++  ++QE YTRYQ + QIK++IF  K+ CS +    LA  ++QSELGD++    +  Y+   + + DQ    E  ++  HK  +G  P DAE  Y+  AK+L  YG DL+          C+ +                ++Q G++A G+ V+ +    NT+   W+ + KV  K K F ++L                  +R    +   +       L F   +   AK  W + +E HSFFR+K P ++ R         F  ++L + F  SGR  L  + + ++R ++  + F R PS    +R   G             P G     +N  S + SN                                        SVTQ+ + P A  A         H+S+       TI+K+         P D  +    + S+ R    +  +   ++    LFE       SP    YS      N  S QP       + +      N  +T  +S + L+      +   R     +GF +KGG D   PV V+KV PNT AD+C P++ EGD+++ IN      L +D++  +I+   +++   +L L ++P     V        +EE+E     +P         NL++   L  +SL    D L  G+ +  +E +Y++   L + EA+K EN+ KNRY+DI PYD TR+ + NS   DYINAN + +EIP       + +YIA+QGP+ +T++DF  M+ +  S LVVMLT ++E GR KC++YWP  G+ L+L  G  + C SEK  +T  FV REF L  K+S E R   H+QY+ WPDH V   P    +F+  ++M R             Q+R                                        S+ + P++VHCSAGIGRTGV+I MD A++ +E +++   L IV+ +R+QRA ++Q+  QY FVC  I   Y
Sbjct:   31 VTVLFLDDTTHTFRIEKRAKGADLLEQVYQFLELSERDYFGLLFPSKPGDV----VRWVDAQKLFKKQCNNIALDNDSVPLLEFRVKFYVSDPSRLQEEYTRYQFYLQIKRNIFLGKLPCSNNTQCLLASYTVQSELGDFNPHEHQMGYLSNMQLLADQTVEAERKISELHKLHRGQLPADAEYNYLEHAKRLDLYGIDLHKAIVIFVKKLCKYLVKIYLLLLLEQDSNSKELQLGVSAIGLLVFQNSLRVNTF--SWSKMVKVSFKRKDFFIQL------------------RREPSENYDTL-------LGFSMTSHKHAKALWKSCVEHHSFFRLKRPHRLSR---------FLNLTLGSKFYYSGRTELQAVQESKQRGKI-HKVFIRSPS----KRLAAGA------------PIGAALPLTNGCSGSDSN---------------------------------------GSVTQNGKAPSALAA---------HTSIL------TITKTSR-------PHDNKVTSKQTDSMPRKAWEQQSDEYDIQ----LFE-------SPVPPTYSTGSHSPN--SGQP-------LGAAITTYINGCTTAAESGNDLVTIRLLADEQGR-----FGFNVKGGIDLGLPVQVSKVVPNTPADRCIPRVREGDEVVLINGREVQGLKHDQVVTMIRECRNIRNGELL-LTMRPFPLAPV-------LSEEEEPLYQYVPENDEICSHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPENVAKNRYRDISPYDCTRVTLVNSSTGDYINANYVNMEIPGG----IINRYIATQGPLANTTTDFWRMVQQESSHLVVMLTTVMEAGRQKCHQYWPLTGDELQLGEGFSVRCLSEKPDETGSFVFREFLLCDKRSGEQRHIQHMQYLAWPDHCVPSDPNLFLEFVERVRMARNRTLLQEIEESLKQVRLLDADADENGGLMGERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMESREAVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAY 967
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Cavefish
Match: ptpn4a (protein tyrosine phosphatase non-receptor type 4a [Source:ZFIN;Acc:ZDB-GENE-030616-449])

HSP 1 Score: 340.502 bits (872), Expect = 7.485e-100
Identity = 184/463 (39.74%), Postives = 278/463 (60.04%), Query Frame = 2 
Query: 1826 PKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSN----STSTMTQSTDKLIDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLP---PLPRKNLVNDI-RLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSD-YINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            PK SR ++ +L            LS S   + N ++       +T   + + ++  D  V I M+P +  ++GF + GG D K PVIV++V P T+AD C P+L EGDQ++ IN     E T+D++   IK++       ++ LV    +Y  V+E       E D   +P   P     L  D  R +++ L+D L  G+ +  F++LY+++ G+TM+ AK  +NI+KNRY+DI PYD TR+++K +D YINAN I +EIP S   + + +YIA QGP+ +T SDF  M WE  S +VVMLT  +E+GR KC++YWP+   T     G Q+ C++E+    F++RE  L   ++ E+R+ T +QY+ WPDH VP    DFL F+ ++R  R+ + EP+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  Q++FVC AI+  Y
Sbjct:  467 PKQSRKNLSQLI-----------LSHSQQDLDNHINEMYDIPVATEKATLNGVVPHDNLVLIKMKPDENGRFGFNVTGGSDQKMPVIVSRVAPGTSADLCVPRLNEGDQVVLINGRDISEHTHDQVVMFIKASCESHSGELILLVRPNAIYDVVEEKL---EMEPDFQYIPAKSPTDPSQLDQDAWRESMQQLKDGLSSGAVLAQFDQLYRKRPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGTDDYINANYINMEIPAS---SIINRYIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPNPSGTATYD-GFQVSCQTEEGNSAFLVREMTLTHIETEESRELTQIQYLAWPDHGVPDDSTDFLDFVALVRSKRAGKDEPVVVHCSAGIGRTGVLITMETAMCLMECSQPVYPLDIVRTMRDQRAMMIQTPSQFKFVCEAILRVY 911

HSP 2 Score: 191.43 bits (485), Expect = 2.482e-49
Identity = 136/430 (31.63%), Postives = 203/430 (47.21%), Query Frame = 2 
Query:  143 NKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFK--ISLANMFS-GRRTLPELLDIRRRNRLMDRSFARIPSKRYNR------------RNTPGGERQSIVSAETNRPTG 1384
             +SYNV A+E A ++  ++ +   + LLD T + F ++    G   LD+V   LE+ ERDYFG+   DD         +WL  NK +RKQ+K   S     FRV+F  ++  ++QE YTRYQ F QIKQDI + ++ C  + A  LA  ++QSELGDY  +     Y+  + FIP+Q   FE +VA  H+   GL P ++E  Y+NTA+ L  YG +L Y     + ++  G+ + GI +Y +    N +  PW  I K+  K K F ++L                      + D++   + +   L F      A K  W   +E H+FFR+  P        +   ++FF    SL + F    RT  + +   +   + DR FAR PSK   R            RN+   ER    S  T  P G
Sbjct:   10 GRSYNVRASELA-RDRQHTEVVCNIVLLDNTVQPFKVNKHDQGQVLLDTVFKHLELTERDYFGLHLADDSSDCP----RWLDPNKPIRKQLKRG-SPHHLNFRVKFFVSDPSKLQEEYTRYQYFLQIKQDILSGRLPCPHNTAALLASYTVQSELGDYSEAENPPGYLSGYCFIPNQPQGFEKEVAKHHQQHSGLSPAESEFNYLNTARTLEHYGVELHYARDQSNTEILIGVMSAGIVIYKNRVRINCF--PWLKIVKISFKCKQFFIQL----------------------RKDANETRETL---LGFNMVNYRACKNLWKTCVEHHTFFRLDQP--------VPPQKNFFAHYFSLGSKFRYCGRTEAQSVQYGKEKGIKDRVFARSPSKPLARKLMGMTDWEAVSRNSLSEERLETQSLPTRSPPG 398
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Cavefish
Match: ptpn4b (protein tyrosine phosphatase non-receptor type 4b [Source:ZFIN;Acc:ZDB-GENE-030131-6259])

HSP 1 Score: 329.331 bits (843), Expect = 1.361e-95
Identity = 171/417 (41.01%), Postives = 255/417 (61.15%), Query Frame = 2 
Query: 1955 QSTDKLIDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPP---LPRKNLVND-IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS-DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYN 3181
            +S +  +  D  V I M+P +  ++GF +KGG D + P+IV++V P TAAD C P+L EGDQ++ IN     + T+D++  +IK++   +   ++ L+V+P    +VDE     + E +   +P    L R +   D  + + + L D L  GS +  F++LY+++ G++M+ A+  +N++KNRY+DI PYD TR+V+K + DYINAN I +EI        V +YIA QGP+  T  DF  M+WE  + LVVMLT  +E+GR KC++YWP+   T     G Q+ C SE     ++LR   L   +S E R+   +QY+ WPDH VP    DFL F+ ++R  R    E +VVHCSAGIGRTGV+ITM+ A+  +E  QS   L IV+ +R+QRAM+IQ+  QY FVC AI+  Y+
Sbjct:  520 KSMNGAVPHDNLVLIKMKPDENGRFGFNVKGGADQRMPIIVSRVAPGTAADLCVPRLNEGDQVVLINGRDISDYTHDDVVMLIKASCENQSAELI-LLVRPNAIYDVDEEDEKLDLESEFHYIPESCGLDRSHSEPDGWKSSFQLLRDGLSSGSVLAQFDQLYRKRPGMSMSCARLPQNVSKNRYRDISPYDTTRVVLKGTEDYINANYINMEIT---GGGGVRRYIACQGPLPGTCGDFWQMVWEQSATLVVMLTTQVERGRVKCHQYWPNVSAT-GTYGGFQVTCISEDGNSAYLLRALTLTHLESKEERQLCQMQYMAWPDHGVPDDSTDFLNFVSLVRSKRGDSQEAVVVHCSAGIGRTGVLITMETAMCLIERSQSVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYD 931

HSP 2 Score: 181.8 bits (460), Expect = 3.434e-46
Identity = 123/384 (32.03%), Postives = 191/384 (49.74%), Query Frame = 2 
Query:  215 VKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFK--ISLANMFS-GRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSI 1354
            V LLD T + F ++ +  G   LD V + L++ ERDYFG+Q  D+  +      +WL  NK +RKQ+K  ++     FRV+F  +E  ++QE YTRY  F Q+KQDI + ++ C ++ A  LA  ++Q+ELGDY  S     Y+ EF FIP+    FE +VA  H+   GL P  AE  Y++ A  L  YG +L Y       +V  G+ + GI++Y +  ++ ++  PW  I K+  K+K F ++L                  + S K+  S+        L F      A K  W   +E H+FFR++ P          + +SFF    +L + F    RT  + +   +   + DR FAR PSK   RR   G + +++
Sbjct:   49 VLLLDNTVQAFRVNKQEQGQALLDIVFEHLQLTERDYFGLQLTDETSENQ----RWLDPNKPIRKQLKR-VAPNNLSFRVKFFVSEPSKLQEEYTRYLYFLQLKQDILSGRLPCPQNAAALLASYAIQAELGDYSQSEHLPGYLSEFSFIPNPPEDFEKEVAKLHQQHNGLSPAQAEFNYLSAASSLDLYGVELHYARDQTTAEVYIGVMSAGISIYKN-RVRVSH-FPWVKIVKISFKSKQFFIQL-----------------RKESSKSRESL--------LGFSMMNYRACKNVWKACVEHHTFFRLERPAP--------QQKSFFAHYFTLGSKFRYCGRTEAQSVQYGKERGVKDRVFARSPSKPLVRRLVSGMDWETV 392
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Cavefish
Match: ptpn3 (protein tyrosine phosphatase non-receptor type 3 [Source:NCBI gene;Acc:103022005])

HSP 1 Score: 316.235 bits (809), Expect = 5.799e-92
Identity = 157/392 (40.05%), Postives = 234/392 (59.69%), Query Frame = 2 
Query: 2015 DSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK--NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKS--NETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            D K+GF +KGG D K P+ ++ V PN+ A +C P L EGDQ++ IN     E T+ ++   IK++       +  LV +  + L  +           ++ +PP P       +  ++  LE  L  G+ +  FEKLY++K GL M+ AK+SEN++KNRYKD+LPYD TR+V++    +YINA+ +K E      +  V  Y+A+QGP+ HT + F   +WE  + +++MLT L E+GR+KC++YWP   E     + LQ+ C SE+C   +V RE  L  +   + R  THLQY+ WPDH VP    DFL F++ +R  R   +EP+VVHCSAGIGRTGV+ITM+ A+  +E  +    L I+  +R QRAM++Q+  Q+ FVC AI+  Y
Sbjct:  451 DGKFGFNVKGGVDQKMPLAISHVNPNSPAGRCVPALLEGDQVLLINGRDISEHTHQQVVMFIKASRESHSKELALLVRRKGISLRAEPTLQIGGGLNLQEEMPPPPSHPSGESLEESMARLEKGLSSGTLLMQFEKLYRKKPGLAMSCAKQSENLDKNRYKDVLPYDITRVVLQAEEDNYINASHVKTE-----PAGGVLHYVAAQGPLPHTCTHFWRSVWEQGATVIIMLTTLTERGRTKCHQYWPHPPEVKDYGY-LQVCCHSEECNLAYVTRELTLTHTQLGQQRSITHLQYVAWPDHGVPEDSSDFLDFVQAMRSKRMD-TEPLVVHCSAGIGRTGVLITMETALILMENTKPVYPLEILTSLREQRAMMVQTSCQFSFVCEAILRVY 835

HSP 2 Score: 134.035 bits (336), Expect = 2.229e-31
Identity = 95/330 (28.79%), Postives = 152/330 (46.06%), Query Frame = 2 
Query:  197 SHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFY--FRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDD-QVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSI 1177
            S I   V   D T   F++     G    D  C+ L I+E+ YF +Q  +D    +++  +WL  NK  +KQ+K       FY  FRVRF  ++   +Q   TR+  F QIK+DI   ++ C     V LA  ++QSE GDY   T    YV +  FIPDQ+  F   V S H   KGL   +AEL Y+NTA+ L  YG +L++ +  ++  +  G+ + G+ ++   ++  +   PW ++ K+  K K F + L             H +  Q+ V                   P   A K  W + ++ H+F+  K  + + +  S+
Sbjct:   29 SSITCVVLFPDVTMHSFSVGKNDAGHLLFDQACEHLGIVEKHYFSLQISED----SSSSPRWLDPNKPFKKQLK---GTDPFYLIFRVRFFISDPNSLQHEQTRHFYFLQIKKDIREGRLKCPLSSGVVLASYAVQSEFGDYVPET-PAGYVDKIHFIPDQDKDFLFKVESLHPQHKGLSQSEAELCYLNTARTLDLYGVELHSARDANNPSLWVGIASGGVAMFC--NLVCSSFFPWINVIKISFKRKRFFIHLRRK----------HGEVGQQVVSVS---------------MPNSRACKNLWRSCVDHHTFYNRKSAQAVSKTRSV 323
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Cavefish
Match: ENSAMXT00000036551.1 (protein tyrosine phosphatase non-receptor type 12 [Source:NCBI gene;Acc:103037814])

HSP 1 Score: 201.83 bits (512), Expect = 1.199e-53
Identity = 106/291 (36.43%), Postives = 163/291 (56.01%), Query Frame = 2 
Query: 2345 VNDIRLTIKSLEDSLKDGSAVQVFEKL---YKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK------NSDYINANIIK-VEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLE---MKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            V  +R   +  ED+   GS      +L   Y+ ++    N  +K EN+ KNRYKDILP+D +R+ ++      ++DYINAN IK ++ P++        YIA+QGP+ +T  DF  MIWE    ++VM     E GR KC +Y+P  G+        +I CESE+    + +R   ++  NETR+ T   YINWPDHDVP   D  L  + ++R+ +     PI VHCSAG GRTG +  +D   + L+   + + F+V  +++++R QR   +Q+++QYE V RAI   +
Sbjct:   14 VQAMRTGDQGGEDNF--GSDFMRLRRLSTKYRTEKIFPTNVGEKEENVKKNRYKDILPFDHSRVKVQLKTSNQDTDYINANFIKGIDGPEA--------YIATQGPLPNTVIDFWRMIWEYNVAVIVMACREFEMGRKKCERYYPQFGDEPMSFGPFRISCESEQPRTDYFIRNLTVEFENETRRITQFHYINWPDHDVPSSFDSILDMIALMREYQEHDDVPICVHCSAGCGRTGAICAIDYTWNLLKAGRIPEDFNVFQLIQEMRTQRHSAVQTKEQYELVHRAIAQLF 294
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Cavefish
Match: ENSAMXT00000016537.2 (protein tyrosine phosphatase non-receptor type 12 [Source:NCBI gene;Acc:103037814])

HSP 1 Score: 202.216 bits (513), Expect = 1.210e-53
Identity = 106/291 (36.43%), Postives = 163/291 (56.01%), Query Frame = 2 
Query: 2345 VNDIRLTIKSLEDSLKDGSAVQVFEKL---YKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK------NSDYINANIIK-VEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLE---MKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            V  +R   +  ED+   GS      +L   Y+ ++    N  +K EN+ KNRYKDILP+D +R+ ++      ++DYINAN IK ++ P++        YIA+QGP+ +T  DF  MIWE    ++VM     E GR KC +Y+P  G+        +I CESE+    + +R   ++  NETR+ T   YINWPDHDVP   D  L  + ++R+ +     PI VHCSAG GRTG +  +D   + L+   + + F+V  +++++R QR   +Q+++QYE V RAI   +
Sbjct:   14 VQAMRTGDQGGEDNF--GSDFMRLRRLSTKYRTEKIFPTNVGEKEENVKKNRYKDILPFDHSRVKVQLKTSNQDTDYINANFIKGIDGPEA--------YIATQGPLPNTVIDFWRMIWEYNVAVIVMACREFEMGRKKCERYYPQFGDEPMSFGPFRISCESEQPRTDYFIRNLTVEFENETRRITQFHYINWPDHDVPSSFDSILDMIALMREYQEHDDVPICVHCSAGCGRTGAICAIDYTWNLLKAGRIPEDFNVFQLIQEMRTQRHSAVQTKEQYELVHRAIAQLF 294
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001312.1 (pep scaffold:Pmarinus_7.0:GL477231:34421:73675:-1 gene:ENSPMAG00000001156.1 transcript:ENSPMAT00000001312.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 312.768 bits (800), Expect = 1.598e-90
Identity = 169/422 (40.05%), Postives = 259/422 (61.37%), Query Frame = 2 
Query: 1961 TDKLIDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRK----NLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK-NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQS-------QKQYEFVCRAIIYYYN 3181
             + L+  +  V + M+P D  ++GF +KGG D K  V V++V P T AD C P+L EGDQ+I IN     E T+D++ + I+++ +      L L+++P     V E     ++E D   +P   R+       + +R +++ L ++L  G A+  FE+LY++K G+++  AK S N ++NRY+D+LPYD TR+V+  N DYINAN I +EI    +S+T+ +YIA QGP+  T + F  M+WE    LV+MLT L E+GR KC++YWPD   + +   G  + C+SE+  +  + R+  L+  ++NE R  T LQY+ WPDH VP     FL F++ +R  R   ++P+VVHCSAGIGRTGV+ITM+ A+  +E  +S   L IV+ +R+QRAM+IQ+       Q QY+FVC AI+  Y+
Sbjct:  526 ANGLLPHEPLVLVRMKPDDQGRFGFNVKGGVDQKMLVTVSRVAPGTPADLCVPRLNEGDQVILINGRDVSEHTHDQVVQFIRAS-TESHSGELVLLIRPSA---VYEELERADSEPDFQYIPEKTRECSSPGERHVVRTSMQQLREALDTGQALLQFEQLYRKKPGMSLGMAKMSCNSSRNRYRDVLPYDATRVVLSGNEDYINANYINMEIT---SSSTINRYIACQGPLPSTCAHFWQMVWEQGCSLVIMLTTLTERGRPKCHQYWPDLPGS-ETYGGFFVLCDSEEESEASIERKLTLRNVENNEERGVTQLQYVAWPDHGVPDDSSHFLGFVRDVR-TRRDHAQPVVVHCSAGIGRTGVLITMETALCLMECNESVYPLDIVRTMRDQRAMMIQTPPCHTRGQCQYKFVCEAILRVYD 938

HSP 2 Score: 186.037 bits (471), Expect = 2.693e-48
Identity = 127/401 (31.67%), Postives = 190/401 (47.38%), Query Frame = 2 
Query:  149 SYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDD-QVQFGLNAHGITVYNSP-DIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPEL-LDIRRRNRLMDRSFARIPSKRYNRRNTPGGE 1342
            +YNV  +E A ++   +     + LLD T+     +    G   LD+V   L++ E DYFG+Q+ DD  +      +WL   K +RKQIK   S   F FRV+F   +  ++QE YTRY  F Q++ DI   ++ C  + A  LA   +QSELGDY  +     Y+ + RF+P Q   FE +VA  HK   G+ P DAE  Y+N AK +  YG +L+  +   + ++  G+ A G+ VYN+   I N    PW  I K+  K K F V+L   Q                         ++   + + F      A K  W   +E H+FFR+  P      G + +   +F +     +SGR  +  +     R NR  +R+FAR PS+R+ RR   G E
Sbjct:   12 TYNVRTSELA-RDRHRTEALCHINLLDNTAITLRANKSEAGKALLDAVFAHLDLAETDYFGLQFADDSTETP----RWLDPTKPLRKQIKRS-SPYIFNFRVKFFVTDPSKLQEEYTRYHYFLQLRNDILEARLPCPHNTAALLASYIVQSELGDYSETEHLPGYLSDLRFLPRQGLDFEKEVAKLHKQHVGMTPADAEFNYLNVAKNVEFYGVELHYARDQSNVEIMVGVTAGGVNVYNNGVRISN---FPWIKIVKIFFKLKHFFVQLRKEQ-------------------------NETRENIIGFNLGNYRACKTLWKACVEHHTFFRMARPASPPHLGFLAQ---YFSLGSKFRYSGRTEMQTVQYGKERSNR--NRNFARSPSQRFPRRTISGKE 373
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Sea Lamprey
Match: PTPN12 (protein tyrosine phosphatase non-receptor type 12 [Source:HGNC Symbol;Acc:HGNC:9645])

HSP 1 Score: 177.563 bits (449), Expect = 3.707e-49
Identity = 94/258 (36.43%), Postives = 143/258 (55.43%), Query Frame = 2 
Query: 2426 YKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK------NSDYINANIIK-VEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWP-DQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMK---QSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAI 3166
            Y+  +       +  +N+ KNRYKDILP++ +R+ +       NSDYINAN IK V  P++        YIA+QGP+ HT  DF +M+WE+  +++VM    +E GR KC +Y+   Q E L L        E +   + + +R   +   NE+R      Y NWPDHDVP   D  L  + ++R+ +     PI VHCSAG GRTG +  +D   + L++    ++FSV ++++D+R QR   +Q++ QYE V  AI
Sbjct:   11 YRSDRTYPTTSGENEDNMRKNRYKDILPFEHSRVKLAIQLPAVNSDYINANFIKGVSNPRA--------YIATQGPLPHTLVDFWSMLWEHNVKVIVMACQEVEMGRKKCERYYALTQEEPLTLGPFTISLVEKQHRGEDYCIRTLSVHYGNESRTVFQFHYSNWPDHDVPSSFDPILEMIAIMREYQDDEDSPICVHCSAGCGRTGAICAIDYTRNLLKLGKIPENFSVFNLIQDMRTQRPSAVQTKDQYELVHCAI 260
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009934.1 (pep scaffold:Pmarinus_7.0:GL479331:74:24469:1 gene:ENSPMAG00000008984.1 transcript:ENSPMAT00000009934.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 176.407 bits (446), Expect = 4.293e-45
Identity = 82/276 (29.71%), Postives = 156/276 (56.52%), Query Frame = 2 
Query: 2366 IKSLEDSLKDGSAVQVFEKLYKQKQGLTMNE----AKKSENINKNRYKDILPYDQTRIVI--KNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKK--SNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAII 3169
            +++  + L++  A Q  EK +++   LT  +    A   EN ++NRY+++LP+D TR+ +  +  DYINA+ + +             Y+A QGP+ HT++ F  M+WE ++ ++ MLT   E GR+KC++YWP+           ++  E ++ + +F +R   + K  +   ++ T LQ+  WPDH  P      + F++  R+++     P+V HCSAG+GR+G +I +D  +++++    F++  IV+++R QR  ++Q+ +QY F  +A +
Sbjct:  773 LEAFINKLQEHIAQQGPEKEFQRLCNLTPRDGCLVASAVENRDRNRYRNVLPFDATRVALSGREDDYINASHVALRA-----GDAALAYVACQGPLPHTAAHFWQMVWEQRARVLAMLTLETELGRAKCHRYWPESRSRATEVGPYRLVLEQQQTLKSFCIRVIMITKLETGIRQRVTQLQFTQWPDHGAPASAGPLVRFLRFARRLQ--EPGPLVTHCSAGVGRSGALICLDAVLAHIDHGLEFNIADIVREMRTQRYGMVQTLEQYIFCYKAAL 1041
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Sea Lamprey
Match: ptprk (protein tyrosine phosphatase receptor type K [Source:ZFIN;Acc:ZDB-GENE-030131-9834])

HSP 1 Score: 176.792 bits (447), Expect = 6.337e-45
Identity = 84/260 (32.31%), Postives = 146/260 (56.15%), Query Frame = 2 
Query: 2414 FEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVI------KNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNE--TRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAII 3169
            +E  + + Q    + AK+ EN  KNRY +I+ YD +R+++      +NSDYINAN +               YIA+QGP+  T   F  MIW+ +S  ++M+T+L+E GR KC KYWPD  +       +++     + +  +++R FR++++ +   R+     +  WPDH VP      LAF++ I+ +    + P+VVHCSAG GRTG  + +DI +   E +    + + V+++R +R  ++Q+++QY F+  A++
Sbjct:  922 YESFF-EGQSAPWDVAKRDENRAKNRYGNIIAYDHSRVMLNVLDEEQNSDYINANYVD-------GYYRTHHYIATQGPLPDTVGGFWRMIWQERSASIIMVTNLVEVGRIKCCKYWPDGSDVYG---DIKVTLADTEMLSEYIIRTFRVERAGQEDIREVRQFHFTGWPDHGVPYHATGLLAFIRRIKALDPPHAGPLVVHCSAGAGRTGCYMVIDIMLDMAESEGVIDIYNCVRELRTRRVNMVQTEEQYVFIHDAML 1170

HSP 2 Score: 63.1586 bits (152), Expect = 4.417e-10
Identity = 50/188 (26.60%), Postives = 84/188 (44.68%), Query Frame = 2 
Query: 2474 NINKNRYKDILPYDQTRIVI-----KNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRL----KKSNETRKFTHLQYINWP-DHDVPIKMDDFLAFMKMIRQIRSSRS--EPIVVHC 2998
            N  KNRY D+LP D+    +      +S+YINA ++     + P++     +I +Q P+ +T  DF  ++++     +VML +L       C +YWP++G    L HG +Q+   +       + R FR+    +  +  R      Y+ WP   +VP     FL  +    + R         VVHC
Sbjct: 1231 NHEKNRYHDVLPPDRCLPFLITINGDSSNYINAALMDSY--RQPSA-----FIVTQHPLPNTVKDFWRLVFDYHCTSIVMLNEL--DSNKYCPQYWPEEG---MLCHGPIQVEFVAFNMEGDIITRTFRICNVARPQDGCRMVEQFHYLGWPAGREVPTSRHSFLRLVLAAERWREEYGMDGRTVVHC 1406
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000174.1 (pep scaffold:Pmarinus_7.0:GL479793:24808:47889:1 gene:ENSPMAG00000000154.1 transcript:ENSPMAT00000000174.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 174.481 bits (441), Expect = 2.989e-44
Identity = 94/268 (35.07%), Postives = 149/268 (55.60%), Query Frame = 2 
Query: 2414 FEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIV------IKNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRLK---KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQI--RSSRSEPIVVHC----SAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAII 3169
            +++L    +G  M  A  +EN  KNRY +ILP+D TR+       I +SDYINAN IK         ++  +YIA+QGP+  T  DF  M+WE K   +VMLT+ +E+G+ KC  YWP   +   +++G + +  E +K    + +R   +K   K++E R   H  +  WPDH VP   D    F+++ R     +++  PIVVHC    SAG+GRTG  I++D  +  ++ K    +  IV D+R  R +++Q++ QY F+ + I+
Sbjct: 1140 YQELSSVGKGQAMEAATLAENRTKNRYTNILPFDVTRVKLASVEDIPHSDYINANYIK-------GHSSSREYIAAQGPLAGTREDFWRMVWEQKVNQIVMLTNCVERGQPKCECYWP--MDITPVRYGDIGLVMEWDKPSPEWTIRHLVVKAQHKTDEKRSLYHFHFTAWPDHGVPDTTDSLTNFVRLFRTHVNTTNKGGPIVVHCRCGSSAGVGRTGTFISLDHLLQDIDKKPEIDIYGIVHDMRMSRVLMVQTEMQYIFIHKCIL 1398
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Yeast
Match: PTP1 (Phosphotyrosine-specific protein phosphatase; dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation [Source:SGD;Acc:S000002389])

HSP 1 Score: 111.309 bits (277), Expect = 8.560e-27
Identity = 81/281 (28.83%), Postives = 134/281 (47.69%), Query Frame = 2 
Query: 2474 NINKNRYKDILPYDQTRIVIK---NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWEN---KSELVVMLTDLLEKGRSKCYKYWPDQG------------------ETLKLQHGLQI-FCESEKCIDTFVLREFRLKKSNE----TRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRS--SRSEPIVVHCSAGIGRTGVVITMD-IAISYLEMK-------------QSFS---VLSIVKDIRNQRAMLIQSQKQYEFVCRAIIY 3172
            N  +NRY +I+PY++ R+ +K    +DYINA+ +KV +P    S     YIA+QGP   T   F  M + N    + ++VM+T L+E  R KCY+YWP  G                  +  +    L+I F    K  D + + + +L  ++      +   H  +  W D + P   ++ +  M++     S  SR  PI+VHCSAG+GRTG  I +D +    L+ K             + ++   +  IV  +R+QR  ++Q++ Q+ F+  A  Y
Sbjct:   52 NDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQ--SIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKP---EEVVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKY 327
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Yeast
Match: PTP2 (Nuclear phosphotyrosine-specific phosphatase involved in osmosensing; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; with Msg5p co-regulates the calcium signaling pathway [Source:SGD;Acc:S000005734])

HSP 1 Score: 93.9745 bits (232), Expect = 6.360e-20
Identity = 86/342 (25.15%), Postives = 135/342 (39.47%), Query Frame = 2 
Query: 2471 ENINKNRYKDILPYDQTRIVIKNS-----------------------------------DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPD---QGETLKLQHGLQIFCESEKCIDTFVLREFRLKKS--------------------------NETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIR------------------------------QIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFS------------VLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            ++  KNRY +ILPY+ +R+ + +S                                   DYINAN +K+    +P+    FKYIA+Q P+  T  DF  +I  NK ++++ L    E    K   YW +      T+KLQ+  +  C    C    VLR F++KK+                          +E      LQY NW D    + M+D +   K+                                 + ++ S P++VHCSAG GRTGV +T+D  +S L    + S            +  IV ++R QR  ++Q+  QY     A++ Y+
Sbjct:  407 QSFTKNRYSNILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLT-QINPD----FKYIATQAPLPSTMDDFWKVITLNKVKVIISLNSDDELNLRKWDIYWNNLSYSNHTIKLQNTWENICNINGC----VLRVFQVKKTAPQNDNISQDCDLPHNGDLTSITMAVSEPFIVYQLQYKNWLD-SCGVDMNDIIKLHKVKNSLLFNPQSFITSLEKDVCKPDLIDDNNSELHLDTANSSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIACYEALLNYF 738
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Yeast
Match: PTP3 (Phosphotyrosine-specific protein phosphatase; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm [Source:SGD;Acc:S000000877])

HSP 1 Score: 69.3218 bits (168), Expect = 2.859e-12
Identity = 42/119 (35.29%), Postives = 57/119 (47.90%), Query Frame = 2 
Query: 2483 KNRYKDILPYDQTRIVIKNS--------------------DYINANIIKVEIPK-SPNSTTVF----------KYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYW 2746
            KNRYKDI PY+ +R+++K                      +YINAN +   +P+ S    + F          +YIA+Q PM  T  DF T I  N   LV+ LT+  E G  KCY+YW
Sbjct:  530 KNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYL--SLPRFSVEQNSSFQTTTTTTRRVRYIATQAPMPSTVHDFYTCILNNGVPLVLSLTNDFENGIEKCYRYW 646
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Nematostella
Match: EDO44823 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUW8])

HSP 1 Score: 300.442 bits (768), Expect = 1.624e-86
Identity = 172/485 (35.46%), Postives = 276/485 (56.91%), Query Frame = 2 
Query: 1829 KASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNST---STMTQSTDKL-----IDTDTRVEIAMRP-IDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYL-----NVDE---HTSS---------NNTEEDEDSLPPLPRKNLVND---IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRI-VIKNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCID-TFVLREFRLKKSN--ETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNN 3184
            K S Y  +       ++ PN+      ++ K +LS S    +T +  T +L        +  + + M P  + ++GF ++GG D   PVIV+K+   T AD C P+L EGD+II IN +    L + EI ++I+S  S  + N L L ++P ++      ++D+   HT S          + +E E +L     K    D   ++++I+ L ++L+ G  +  F++LY++K G+ M++A+K EN+ KNRY+DILPYD+TR+ + K SDYINAN + +E+P   +   V +YIA+QGP+  T  DF  MIWE +S LV+MLT  +E+GR KC++YWP+  +T    + L++ C   +    ++V RE  +  +    +R    LQY+ WPDHDVP    DFL F+  +R  R   S P VVHCSAG+GR+GV++ ++ A   +E  +    L +V+ +R+QR  LIQ+  Q+ FVC A +  Y++
Sbjct:  395 KDSMYGEKHAPPFHYASAPNSTEKLDRTNFKRSLSTSANVGATKSGLTPELQANGSTPQEGLITVRMEPDKEGRFGFNVQGGADINLPVIVSKIARGTPADLCMPQLQEGDEIIFINGQAMKGLIHQEIVDLIRSV-SQSRSNTLILTIRPNVFAPNGSRSLDDSPVHTVSVEQYNAQELKHEKEVEAALVSKREKQQQRDCEGLKVSIEQLRENLESGDLLVYFQELYRKKPGMAMDDARKPENLPKNRYRDILPYDETRVKLFKGSDYINANFVNMEVP---SHGIVLRYIAAQGPLEKTCGDFWQMIWEQESTLVIMLTTTMERGRVKCHQYWPEGEDTWTFGN-LEVVCNKIRDFSPSYVYREMYVTDTTTLRSRVIIQLQYLAWPDHDVPDDATDFLEFVHSVRHYREGTSTPAVVHCSAGVGRSGVLMFIETAFGMIEGAEPVYPLELVRRMRDQRGSLIQTPGQFLFVCEATLKAYDD 874

HSP 2 Score: 176.022 bits (445), Expect = 6.170e-45
Identity = 124/394 (31.47%), Postives = 191/394 (48.48%), Query Frame = 2 
Query:  203 IKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDD--DDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQVQF-GLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSIVSAETNR 1375
            I+  V+LLD++  I ++   A G   L+ V   L+I E+ YFG+QY  D  D+ +     +WL+ +K++RKQ K       FYF VRF  ++  ++ E  TRY  + QIK+DI   ++ C  D A +L+   LQ+ELGDY        YV EFRFIPDQ   FE   A FHK   G  P DAE  ++  AK L  YG DL+  +  D    F G++A G+TVY++    N +  PW+ I KV  K K F ++                      ++ D    ++   + + F   T  + K  W   +E HSF+R   PK  E+   + R  S ++      + G+     + + R   R  +    R  S+RY++R+  G   +S+   + +R
Sbjct:   35 IRCVVELLDDSEFIIDVDKNAKGTVLLNEVFRHLDIQEKHYFGLQYVSDSPDNMVGGAKEQWLQDDKIIRKQ-KKGTPPYIFYFCVRFFVSDPSKLVEDLTRYYFYLQIKRDILTGRLPCLYDTAAELSSYILQAELGDYDPKLHLDGYVSEFRFIPDQTDDFEERAAEFHKHHIGQTPADAEFNFLEVAKTLDLYGVDLHCAKDHDGTDLFLGVSALGLTVYHNKCKINFF--PWSKIVKVCFKRKRFFIQ----------------------IRPD---WNEWTDNIIGFQMLTYRSCKNLWKVCVEYHSFYRTHYPKATEK--RVLRMGSKYR------YKGKTEYQAIEESRTHAR-PEPKIVRTLSRRYSKRSDSGTWSRSLRRLDLDR 391
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Nematostella
Match: EDO38304 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDC7])

HSP 1 Score: 194.512 bits (493), Expect = 1.994e-55
Identity = 100/281 (35.59%), Postives = 165/281 (58.72%), Query Frame = 2 
Query: 2354 IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNS---DYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQ-GETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVP---IKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAII 3169
            +++   +L+  L  G   + F+ L + K     +  K   N +KNRY+++LPY+ TR+ +  S   DYINAN I+V +         + YIA+QGP+ +T+ DF  MIWE   E+V M+T   E G+ KC++YWPD   + LKL    ++    +   D+FV R+  +K  +S ++ +  HL ++ WPDH VP   ++M  F+A+M+ +    ++   P+VVHCSAGIGRTG +I +D+A+  +E  + F +   ++D+R QR  +IQ++ QY F  +A +
Sbjct:   16 LKMLTGALQTKLDSGMPEEEFKDLREIKPTDGCDSGKNQANTDKNRYRNVLPYEATRVRLSGSSGEDYINANHIRVLV-----DDDTYHYIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWPDNTNQPLKLGGRFEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSL----ATSQAPVVVHCSAGIGRTGALIAVDVALGLMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACL 287
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Nematostella
Match: EDO48949 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI09])

HSP 1 Score: 180.259 bits (456), Expect = 2.117e-50
Identity = 97/294 (32.99%), Postives = 160/294 (54.42%), Query Frame = 2 
Query: 2357 RLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEA--------KKSENINKNRYKDILPYDQTRIVIK------NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAIS-YLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNNI 3187
             + +  +ED L + +      +L K+ + L   EA        K+ +N+ KNRY D+LPYD  R+ ++       SDYINA+ I    P++P       YIA+QGP+ HT SDF  M+WE    ++V LT L + G  +C++YWP+ G      + + +  E   C D +++R F LK  +++ETR  T   +++WPD +VP      L F + + +    RS PIVVHCS G+GRTG  I +D+ ++  +   +   + + V+ +R+QR  +++++ Q+EF   A+    N I
Sbjct:   15 HVVLSYMEDHLSNKN------RLNKEWEALCNYEAEPSVADLGKQDKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITDHDPRNP------AYIATQGPLAHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWPEDGHETYHIYEVHLVSEHIWC-DDYLVRSFYLKNLQTSETRTVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGRSCPIVVHCSGGVGRTGCYILIDLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAEEVNAI 295
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Nematostella
Match: EDO48358 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJD7])

HSP 1 Score: 175.637 bits (444), Expect = 3.226e-48
Identity = 92/255 (36.08%), Postives = 135/255 (52.94%), Query Frame = 2 
Query: 2429 KQKQGLTMNEAKKSENINKNRYKDILPYDQTRIV------IKNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCI-DTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQS--FSVLSIVKDIRNQRAMLIQSQKQYEFVCRAI 3166
            K+ +  + N  +K  N  KNRYKDILPYD +RIV      +  SDYIN N IK         T    Y+A+QGP+  T  DF  M+  +  ++VVM     E G+ KC +YWP+  E      G++I  ESE+ + D F +R   ++        T   Y  WPDHDVP      +   +  R    S+  P++VHCSAG GRTG +  +D A + L+  ++   SV  IV ++R QR  ++Q+++QY  V +A+
Sbjct:   38 KRDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEIKGVDGSDYINGNYIK-------GPTKNIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRYWPESMEETLTFAGMKISLESEEAMGDGFTVRTLAVQAGKTKHNVTQFHYTAWPDHDVPRSATPLIELTRSFRTFVGSQDTPVLVHCSAGCGRTGTICALDYARTLLQTGRTEELSVFDIVANLRRQRVAMVQTKEQYTLVYKAV 285
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Nematostella
Match: EDO33995 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQN6])

HSP 1 Score: 176.022 bits (445), Expect = 1.376e-46
Identity = 105/268 (39.18%), Postives = 150/268 (55.97%), Query Frame = 2 
Query: 2411 VFEKLYK---QKQGLTMNEAKKSENINKNRYKDILPYDQTRIVI-------KNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHG-LQIFCESEKCIDTFVLREFRLKK-SN--ETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIR-QIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAII 3169
            +FEK YK   +   +T        N  KNRY +I  YD +R+++       +++DYINAN I              KYIA+ GP   T+SDF  M+WE+KS +VVMLT L+EKG+ KC+KYWP++ E    Q+G + +  E ++ +  F +R+F L+K SN  ETR   H  + +WPDHDVP      L F K +R      +S PI VHCSAG+GRTG  I +D  +  ++ +    V S V  IR QR  ++Q   QY F+  A++
Sbjct:   28 LFEKEYKDIKEPVNVTTRHCDNLINKPKNRYGNIKAYDHSRVILSSVQGDSESTDYINANWID-------GFKQEKKYIATIGPKAETTSDFWRMMWEHKSSIVVMLTKLVEKGKVKCHKYWPEENE----QYGEIIVTLEEKEELADFEIRKFFLRKLSNQMETRMVKHFYFTSWPDHDVPEYATGLLEFWKRVRNSWEGPQSGPITVHCSAGVGRTGTFIVIDAMMEQIKEENLLDVYSYVSRIRAQRNFMVQRPSQYSFIHYALL 284

HSP 2 Score: 97.8265 bits (242), Expect = 6.007e-21
Identity = 70/297 (23.57%), Postives = 130/297 (43.77%), Query Frame = 2 
Query: 2345 VNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNE------AKKSENINKNRYKDILPYDQTRIVI------KNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSE----PIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNNI 3187
            V ++R+ +  L + +  G+ +   E+ ++   G   +E      A + +N  KNRY +ILP ++ R+V+      +++ YINA+ ++    K         +IA+Q P+ +T  DF  M+W  +   +VML  L E                                            ++ E R+ +H  Y+ W +H VP K+   L  + +I  ++ +R +    P+VVHCS G+GRTG   T+   +  ++++    V    + +R QR  ++    QY     AI+ Y ++ 
Sbjct:  296 VQNLRMRLMQLAEKVA-GTGMTGLEREFQLLNGAVPDELSDFYTATQPKNSKKNRYPNILPCERCRVVLPAIPDKEDTTYINASYLEGYQEK-------VAFIATQAPLDNTIEDFWRMVWHEEVFCIVMLCGLNEP------------------------------------------LETGEVRQISHFMYLEWTEHAVPTKL---LTIIDLIGDLQKARRKHLDRPVVVHCSDGVGRTGAFCTLFATLERVKLEGVLDVFITARMLRTQRPGMVSHLDQYRLCYEAILAYLDSF 539
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Medaka
Match: ptpn4a (protein tyrosine phosphatase non-receptor type 4 [Source:NCBI gene;Acc:101171899])

HSP 1 Score: 328.561 bits (841), Expect = 5.379e-95
Identity = 172/436 (39.45%), Postives = 266/436 (61.01%), Query Frame = 2 
Query: 1895 LSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEED----EDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSD-YINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            L   ++ M +  +N   T   + + ++  D  V I MRP +  ++GF +KGG D K P+IV++V P T+AD C P+L EGDQ++ IN     + T+D++   IK++       ++ L+V+P    +V E  +   +E D     +  P  P +   + +R ++  L + L  G+ +  F++LY+++ G+TM  AK  +N++KNRY+DI PYD TR+++K++D YINAN I +EIP S   + + +YIA QGP+  T SDF  M WE  S +VVMLT  +E+GR KC++YWP+   +        + C +E+    F++RE  L   KS + R+ T +QY+ WPDH VP    DFL F+ ++R  R+ + +P+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  QY FVC AI+  Y
Sbjct:  491 LDNHVNEMYDVPANPEKT---TLNGVVPHDNLVLIKMRPDEHGRFGFNVKGGVDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGRDISDHTHDQVVMFIKASCESHSGELI-LLVRPNANYDVVEEKA--ESEPDFQYIPEKTPQDPAQVDQHALRDSMSVLREGLSSGAVLSQFDQLYRKRPGMTMLCAKLPQNVSKNRYRDISPYDATRVLLKSTDDYINANYINMEIPAS---SLINRYIACQGPLPTTCSDFWQMTWEQASSMVVMLTTQVERGRVKCHQYWPNPDSSATYG-DFAVTCLNEEGSAAFLVREMTLTDVKSGQQRELTQIQYLAWPDHGVPDDSTDFLDFVALVRSKRAGQDQPVVVHCSAGIGRTGVLITMETALCLMECGQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVY 916

HSP 2 Score: 186.808 bits (473), Expect = 1.141e-47
Identity = 124/405 (30.62%), Postives = 196/405 (48.40%), Query Frame = 2 
Query:  143 NKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSI 1354
             +SYNV A E   ++  ++ +   V LLD + + F +S    G   LD+V   LE+ ERDYFG+   DD         +WL  NK +RKQ+K   S  +  FRV+F   +  ++QE YTRYQ F QIKQDI   ++ C  + A  LA  ++QSELGDY+ +   + Y+ E+ FIP     F  +V+  H+   GL P  AE  Y+NTA+ L  YG +L Y     + ++  G+ + G+ VY +   KN  +  W  I K+  K+K F ++L                      + +++   + +   L F      A K  W   +E H+FFR++ P   ++         +F +     + GR  + + +   +   + DR FAR PSK   R+   G + +S+
Sbjct:   10 GRSYNVRATE-LERDRQHTQVVCNVLLLDNSVQAFRVSKSDHGQVLLDAVFRHLELTERDYFGLHVADDASDAP----RWLDPNKPIRKQLKRG-SPHSLSFRVKFFVTDPSKLQEEYTRYQYFLQIKQDILTGRLPCPNNTAALLASYAVQSELGDYNEAEHSSGYLSEYCFIPAPPQDFHKEVSKHHQQHSGLTPAQAEFNYLNTARTLELYGVELHYARDQRNAEILMGVMSAGVVVYQNRVRKN--LFQWLKIVKISFKSKQFFIQL----------------------RREATETRETL---LGFNMVNYRACKNLWKACVEHHTFFRLEQPIPPQKNFFAH----YFSLGSKYRYCGRTEV-QSVQYGKEKAVKDRVFARSPSKPLARKLMGGTDWESV 376
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Medaka
Match: ptpn4a (protein tyrosine phosphatase non-receptor type 4 [Source:NCBI gene;Acc:101171899])

HSP 1 Score: 332.413 bits (851), Expect = 4.417e-94
Identity = 168/411 (40.88%), Postives = 255/411 (62.04%), Query Frame = 2 
Query: 1970 LIDTDTRVEIAMRPID-SKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEED----EDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSD-YINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLK--KSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            ++  D  V I MRP +  ++GF +KGG D K P+IV++V P T+AD C P+L EGDQ++ IN     + T+D++   IK++       ++ L+V+P    +V E      +E D     +  P  P +   + +R ++  L + L  G+ +  F++LY+++ G+TM  AK  +N++KNRY+DI PYD TR+++K++D YINAN I +EIP S   + + +YIA QGP+  T SDF  M WE  S +VVMLT  +E+GR KC++YWP+   +        + C +E+    F++RE  L   KS + R+ T +QY+ WPDH VP    DFL F+ ++R  R+ + +P+VVHCSAGIGRTGV+ITM+ A+  +E  Q    L IV+ +R+QRAM+IQ+  QY FVC AI+  Y
Sbjct:  988 VVPHDNLVLIKMRPDEHGRFGFNVKGGVDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGRDISDHTHDQVVMFIKASCESHSGELI-LLVRPNANYDVVE--EKAESEPDFQYIPEKTPQDPAQVDQHALRDSMSVLREGLSSGAVLSQFDQLYRKRPGMTMLCAKLPQNVSKNRYRDISPYDATRVLLKSTDDYINANYINMEIPAS---SLINRYIACQGPLPTTCSDFWQMTWEQASSMVVMLTTQVERGRVKCHQYWPNPDSSATYG-DFAVTCLNEEGSAAFLVREMTLTDVKSGQQRELTQIQYLAWPDHGVPDDSTDFLDFVALVRSKRAGQDQPVVVHCSAGIGRTGVLITMETALCLMECGQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVY 1391

HSP 2 Score: 172.555 bits (436), Expect = 6.413e-43
Identity = 114/363 (31.40%), Postives = 172/363 (47.38%), Query Frame = 2 
Query:  269 GFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDL-YTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSI 1354
            G   LD+V   LE+ ERDYFG+   DD         +WL  NK +RKQ+K   S  +  FRV+F   +  ++QE YTRYQ F QIKQDI   ++ C  + A  LA  ++QSELGDY+ +   + Y+ E+ FIP     F  +V+  H+   GL P  AE  Y+NTA+ L  YG +L Y     + ++  G+ + G+ VY +   KN  +  W  I K+  K+K F ++L                  +R        +       L F      A K  W   +E H+FFR++ P   ++         +F +     + G RT  + +   +   + DR FAR PSK   R+   G + +S+
Sbjct:  526 GQVLLDAVFRHLELTERDYFGLHVADDASDAP----RWLDPNKPIRKQLKRG-SPHSLSFRVKFFVTDPSKLQEEYTRYQYFLQIKQDILTGRLPCPNNTAALLASYAVQSELGDYNEAEHSSGYLSEYCFIPAPPQDFHKEVSKHHQQHSGLTPAQAEFNYLNTARTLELYGVELHYARDQRNAEILMGVMSAGVVVYQNRVRKN--LFQWLKIVKISFKSKQFFIQL------------------RREATETRETL-------LGFNMVNYRACKNLWKACVEHHTFFRLEQPIPPQKNFFAH----YFSLGSKYRYCG-RTEVQSVQYGKEKAVKDRVFARSPSKPLARKLMGGTDWESV 851
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Medaka
Match: ptpn3 (protein tyrosine phosphatase non-receptor type 3 [Source:NCBI gene;Acc:101169482])

HSP 1 Score: 301.982 bits (772), Expect = 1.113e-86
Identity = 170/472 (36.02%), Postives = 262/472 (55.51%), Query Frame = 2 
Query: 1838 RYSIQELKSNKASTQPNAKLSGSMS-SMKNALSNSTSTMTQ-------STDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLV-------------VKPRLYLNVDEHTSSNNTEEDEDSLPPLP-RKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKN-SDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKS--NETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            R S+   K ++    PN +LSGS S    +ALS++  ++ +       + D L D D  +       + K+GF +KGG D K P+ V+ + P++ A +  PKL EGD I+ IN     E T+D++   I+++       +  L+             + P L L +  H          DS P  P +   V  +  +++ LE  ++ G+    FE LY++K G++ + ++  EN  KNRY+D+LPYD TR+V+++  DYINA+ I V     P S    +YIA+QGP+  T + F   +WE +   V+MLT L E+GR+KC++YWP   +     H + + C SE+C   +V R F LK +   + R  THLQY+ WPDH VP    DFL F+  +R+ R    EP++VHCSAGIGRTGV+I M+ A++ ++  Q    L IVK +R+QRAM++Q+  Q++FVC AI+  Y
Sbjct:  409 RASVSSSKGSEGDVSPN-RLSGSYSQGPDDALSHADDSIGEEDTPPYYNKDALGDGDLMLICITPDHEGKFGFNVKGGVDQKMPLSVSHIKPDSPAGRSEPKLMEGDLIVLINGRDISEHTHDQVVMFIRASRESHSRQLALLIKRKGSGRVAPSLQLPPTLTLTIPSH----------DSKPQSPGQSERVKTLEESMRQLERGIQSGTLCFHFENLYRRKPGMSQDCSRLPENQEKNRYRDVLPYDATRVVLQSQEDYINASHITV---APPESGVCLQYIAAQGPLPQTCTHFWQTVWEQQIHTVIMLTTLTERGRTKCHQYWPHPPKAKDYGH-MSVECHSEECNLAYVTRRFTLKHTQLGDERAITHLQYVAWPDHGVPDDPSDFLQFVSSVRETRDK--EPLMVHCSAGIGRTGVLIIMETALTLMDGGQPVFPLEIVKTMRDQRAMMVQTTSQFQFVCEAILRVY 863

HSP 2 Score: 139.043 bits (349), Expect = 5.953e-33
Identity = 99/326 (30.37%), Postives = 150/326 (46.01%), Query Frame = 2 
Query:  215 VKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKL-----NNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQ---VQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFF----RVKDPKQ 1156
            V+LLD T E F +S +  G   L  V D L + ER  F +Q ++    +     N    +WL+  K ++KQIK  +S     FRVRF  ++   +Q   TR+  F QI+ DI   ++ C  + AV LA  ++QSE+GD H  +    Y+ +  F+P+QN  F S V   H   KGLK  DAEL ++NTA+ L  YG +L+    MD     +  GL + G+ ++   ++  +   PW  I K+  K K F + L            G +Q  +                 +  +       K  W + ++ HSFF      K PKQ
Sbjct:   10 VQLLDGTIETFRVSKQDEGEVLLSLVFDHLGLQERQLFSLQIRESSTAIASFTANTHSPRWLEPEKPLKKQIKGLVSPFYLNFRVRFFISDPNSLQHDQTRHLYFLQIRSDIREGRLQCPLNAAVVLASYAVQSEIGD-HCPSRAPGYLSKCHFMPEQNEDFLSKVEDLHPQHKGLKQSDAELCFLNTARTLELYGVELHAA--MDTNNTPLMVGLTSSGVAIFC--NMVCSSFFPWGKIIKISFKRKRFFLHLKQKH--------GETQDCE-----------------VPLLLLCPKTCKNLWRSCVDHHSFFSSNRNAKSPKQ 305
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Medaka
Match: ptpn3 (protein tyrosine phosphatase non-receptor type 3 [Source:NCBI gene;Acc:101169482])

HSP 1 Score: 235.728 bits (600), Expect = 2.834e-64
Identity = 149/472 (31.57%), Postives = 233/472 (49.36%), Query Frame = 2 
Query: 1838 RYSIQELKSNKASTQPNAKLSGSMS-SMKNALSNSTSTMTQ-------STDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLV-------------VKPRLYLNVDEHTSSNNTEEDEDSLPPLP-RKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKN-SDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKS--NETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            R S+   K ++    PN +LSGS S    +ALS++  ++ +       + D L D D  +       + K+GF +KGG D K P+ V+ + P++ A +  PKL EGD I+ IN     E T+D++   I+++       +  L+             + P L L +  H          DS P  P +   V  +  +++ LE  ++ G+    FE LY++K G++ + ++  EN  KNRY+D+LPYD TR+V+++  DYINA+ I                                                     +KC++YWP   +     H + + C SE+C   +V R F LK +   + R  THLQY+ WPDH VP    DFL F+  +R+ R    EP++VHCSAGIGRTGV+I M+ A++ ++  Q    L IVK +R+QRAM++Q+  Q++FVC AI+  Y
Sbjct:  409 RASVSSSKGSEGDVSPN-RLSGSYSQGPDDALSHADDSIGEEDTPPYYNKDALGDGDLMLICITPDHEGKFGFNVKGGVDQKMPLSVSHIKPDSPAGRSEPKLMEGDLIVLINGRDISEHTHDQVVMFIRASRESHSRQLALLIKRKGSGRVAPSLQLPPTLTLTIPSH----------DSKPQSPGQSERVKTLEESMRQLERGIQSGTLCFHFENLYRRKPGMSQDCSRLPENQEKNRYRDVLPYDATRVVLQSQEDYINASHIT----------------------------------------------------TKCHQYWPHPPKAKDYGH-MSVECHSEECNLAYVTRRFTLKHTQLGDERAITHLQYVAWPDHGVPDDPSDFLQFVSSVRETRDK--EPLMVHCSAGIGRTGVLIIMETALTLMDGGQPVFPLEIVKTMRDQRAMMVQTTSQFQFVCEAILRVY 814

HSP 2 Score: 138.658 bits (348), Expect = 6.397e-33
Identity = 99/326 (30.37%), Postives = 150/326 (46.01%), Query Frame = 2 
Query:  215 VKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKL-----NNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQ---VQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFF----RVKDPKQ 1156
            V+LLD T E F +S +  G   L  V D L + ER  F +Q ++    +     N    +WL+  K ++KQIK  +S     FRVRF  ++   +Q   TR+  F QI+ DI   ++ C  + AV LA  ++QSE+GD H  +    Y+ +  F+P+QN  F S V   H   KGLK  DAEL ++NTA+ L  YG +L+    MD     +  GL + G+ ++   ++  +   PW  I K+  K K F + L            G +Q  +                 +  +       K  W + ++ HSFF      K PKQ
Sbjct:   10 VQLLDGTIETFRVSKQDEGEVLLSLVFDHLGLQERQLFSLQIRESSTAIASFTANTHSPRWLEPEKPLKKQIKGLVSPFYLNFRVRFFISDPNSLQHDQTRHLYFLQIRSDIREGRLQCPLNAAVVLASYAVQSEIGD-HCPSRAPGYLSKCHFMPEQNEDFLSKVEDLHPQHKGLKQSDAELCFLNTARTLELYGVELHAA--MDTNNTPLMVGLTSSGVAIFC--NMVCSSFFPWGKIIKISFKRKRFFLHLKQKH--------GETQDCE-----------------VPLLLLCPKTCKNLWRSCVDHHSFFSSNRNAKSPKQ 305
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Medaka
Match: ptpn20 (protein tyrosine phosphatase non-receptor type 20 [Source:ZFIN;Acc:ZDB-GENE-090313-90])

HSP 1 Score: 193.356 bits (490), Expect = 1.014e-53
Identity = 103/269 (38.29%), Postives = 162/269 (60.22%), Query Frame = 2 
Query: 2354 IRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVI-KNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRL--KKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEF 3151
            ++  ++ L+  L     V+ F  L   K        K  EN  KNRY+DILPYD+TR+ + +N DYINA+ I++++         F YI+ QGP+  T   F  MIWENKS+++ M+T  LE+GR KC+KYWP++ +        Q+F E+++ ++ F ++  R+   K+ ET    HL++ +WPDH VP   ++ + F++ +R +      PI VHCSAGIGRTGV+I  DI ++ +E   + +V  IVK++R QR  +IQ+++QY F
Sbjct:   80 VKALVQILQHQLDQQELVKEFMALEHLKPSDDCLVGKAPENREKNRYRDILPYDKTRVKLGENQDYINASYIRMQV-----GAEEFFYISCQGPLPSTVPAFWQMIWENKSDVIAMMTQELERGRIKCHKYWPEKQDVPLDTGKHQLFLENQQYLEYFHIKVIRIVEVKTGETHFVHHLKFTHWPDHGVPHCSEELVRFIRYMRALH--HRGPITVHCSAGIGRTGVLICTDIILNLIERDLNINVSDIVKEMRLQRHGMIQTKEQYLF 341
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Planmine SMEST
Match: SMESG000023435.1 (SMESG000023435.1)

HSP 1 Score: 1954.49 bits (5062), Expect = 0.000e+0
Identity = 974/1019 (95.58%), Postives = 975/1019 (95.68%), Query Frame = 2 
Query:  137 MFNKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSIVSAETNRPTGIVYGKSNPTSNNPSNYVKPKLNDKKKTXXXXXXXXXXXXXXXXXXXXPGAFRNKSSVTQSVRVPKASTAKGFQKHPVIHSSMPRQKVTGTISKSQTSINQELTPTDPNIPDIMSRSIGRNEQNKPGNNVSLKEQNILFETKMKTSKSPKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNNICK 3193
            MFNKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNT GGERQSIVSAETNRPTGIVYGKSNPTSNNPSNYVKPKLNDKKKTVESNVSESSDESDHHDLEVEPGAFRNKSSVTQSVRVPK    K               KVTGTISKSQTSINQELTP DPNIPDIMSRSIGRNEQNKPGNN                     ASRYSIQELKSNK STQPNAKLSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEH SSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSDYINANIIKV+IPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNNICK
Sbjct:    1 MFNKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTAGGERQSIVSAETNRPTGIVYGKSNPTSNNPSNYVKPKLNDKKKTVESNVSESSDESDHHDLEVEPGAFRNKSSVTQSVRVPKHQLQK---------------KVTGTISKSQTSINQELTPIDPNIPDIMSRSIGRNEQNKPGNN---------------------ASRYSIQELKSNKGSTQPNAKLSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHASSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSDYINANIIKVDIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNNICK 983
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Planmine SMEST
Match: SMESG000023435.1 (SMESG000023435.1)

HSP 1 Score: 962.985 bits (2488), Expect = 0.000e+0
Identity = 484/503 (96.22%), Postives = 488/503 (97.02%), Query Frame = 2 
Query:  137 MFNKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPGGERQSIVSAETNRPTGIVYGKSNPTSNNPSNYVKPKLNDKKKTXXXXXXXXXXXXXXXXXXXXPGAFRNKSSVTQSVRVPKASTAKGFQKHPVIHSSMPRQKV 1645
            MFNKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNT GGERQSIVSAETNRPTGIVYGKSNPTSNNPSNYVKPKLNDKKKTVESNVSESSDESDHHDLEVEPGAFRNKSSVTQSVRVPK    K F+   +     P +K+
Sbjct:    1 MFNKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQVQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTAGGERQSIVSAETNRPTGIVYGKSNPTSNNPSNYVKPKLNDKKKTVESNVSESSDESDHHDLEVEPGAFRNKSSVTQSVRVPKHQLQKVFKNILLFTLQCPDRKL 503

HSP 2 Score: 74.3294 bits (181), Expect = 2.696e-13
Identity = 36/52 (69.23%), Postives = 39/52 (75.00%), Query Frame = 3 
Query: 1518 KLNPGHFEINLVSHRVFEFPKHQLQKVFKNILLFTLQCPDRKLQERFLNLKH 1673
            ++ PG F       +    PKHQLQKVFKNILLFTLQCPDRKLQERFLNLKH
Sbjct:  461 EVEPGAFRNKSSVTQSVRVPKHQLQKVFKNILLFTLQCPDRKLQERFLNLKH 512
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Planmine SMEST
Match: SMESG000023435.1 (SMESG000023435.1)

HSP 1 Score: 952.97 bits (2462), Expect = 0.000e+0
Identity = 459/462 (99.35%), Postives = 460/462 (99.57%), Query Frame = 2 
Query: 1808 MKTSKSPKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNNICK 3193
            MKTSKSPKASRYSIQELKSNK STQPNAKLSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEH SSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSDYINANIIKV+IPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNNICK
Sbjct:    1 MKTSKSPKASRYSIQELKSNKGSTQPNAKLSGSMSSMKNALSNSTSTMTQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHASSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKNSDYINANIIKVDIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLREFRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYYNNICK 462
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Planmine SMEST
Match: SMESG000022143.1 (SMESG000022143.1)

HSP 1 Score: 334.339 bits (856), Expect = 4.031e-97
Identity = 182/434 (41.94%), Postives = 271/434 (62.44%), Query Frame = 2 
Query: 1952 TQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDED------------------SLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKN---SDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCID--TFVLREFRLKK--SNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            + STD+  D D  +++     + +YGFT++   + KSP+I+  +G NT AD CFP+L  GDQ+I IN E  D LT DE+  IIK++      +++ L V+P  Y+         NT E  D                  S P +   NL +  + ++K LE+S+++   +Q FE +Y++K GLTM EAKK+EN +KNRY+DI PYDQTR+++KN   SDYINA+II ++I    ++  + KYIA+QGP++ TS DF  M WE  + L+VMLT L E+GR KC+KYWP   ET++     QI C  E+  +   F +R+  + +  S E R+  H+QYI+WPDH VP    +F+ F+  +R+ RS   EPIVVHCSAGIGRTGV+ITM+ A+ ++E ++  +++ I++ +R+QRA +IQ+  Q++FVC AII  Y
Sbjct:  593 SHSTDRFYDNDLMIKLRCDR-NRRYGFTVRSTSERKSPIIINFIGKNTPADMCFPRLNVGDQLISINGENVDHLTQDEVISIIKNSSESGCGDII-LKVRPNNYM------VECNTVESSDWDFSITENGSESKSSIISSKPDILSSNL-DPFKESLKFLENSVENDDILQQFESVYRKKPGLTMMEAKKTENFSKNRYRDISPYDQTRVILKNNGSSDYINASIINMQIN---DNGMINKYIAAQGPLLRTSEDFWQMCWEQNTYLIVMLTALSEQGRPKCHKYWPQIYETIEFG-DFQISCLVEEYSEDGGFAIRDLMVYRTVSKEERRVQHMQYISWPDHGVPAVHYEFINFVYKVRKFRSGHFEPIVVHCSAGIGRTGVLITMETAMCFIEARKPINLVDILQTMRDQRASMIQTPAQFKFVCEAIIKVY 1013

HSP 2 Score: 225.328 bits (573), Expect = 4.270e-60
Identity = 140/394 (35.53%), Postives = 215/394 (54.57%), Query Frame = 2 
Query:  137 MFNKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQ-VQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDP---KQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPS 1306
            M   SY VAA E   K    + +K +V LLD   E F L  ++ G   LD + D LE+LERD+FG+QYKD     +  +YKWL   K ++KQ+ T      F+FRV+F P    QM+E YTRY LF Q+K+DIF+ ++ C++D+   L   +LQ+ELGDY+    K+ Y+ EFRF+ +Q    E  ++  H  +K L   +AE +Y+ T  Q+  YG  LYTC  +D + VQ G ++ G +V+ +   K  ++  W+SI K+  K K   +++  +  +    +   S          S +++        +V  +    K  W N ++ H+FFRVK P    QI +  +  +  +FF IS+   F GRRT+P + DI++R+R  DR+F R PS
Sbjct:    1 MLGGSYYVAAREEY-KHHASNDLKCQVVLLDGNVEFFTLQKKSCGHCLLDLIFDTLELLERDFFGLQYKDSHPS-SGKYYKWLNGAKSIKKQL-TGSQPYIFHFRVKFYPNNPSQMKEEYTRYLLFLQLKKDIFDERLHCNQDMVAILGSYALQAELGDYNPQQHKSGYISEFRFVKNQTPVLELKISDLHMKMKQLSQGEAEFEYLRTVCQMDYYGALLYTCLTLDKEIVQIGPSSLGFSVFKNK--KRMHLFLWSSIFKISFKKKKITIQIKSTHFVDQFKNNEESN-------KSSPLMY-------TYVLSSSPLCKTLWQNCVDYHTFFRVKVPPNNSQI-KANTKSKGSNFFGISITPAFCGRRTMPTIEDIQKRSRTTDRTFIRTPS 374
[Close]
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Planmine SMEST
Match: SMESG000022143.1 (SMESG000022143.1)

HSP 1 Score: 334.339 bits (856), Expect = 4.811e-97
Identity = 182/434 (41.94%), Postives = 271/434 (62.44%), Query Frame = 2 
Query: 1952 TQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVGPNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVLNLVVKPRLYLNVDEHTSSNNTEEDED------------------SLPPLPRKNLVNDIRLTIKSLEDSLKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIKN---SDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSELVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCID--TFVLREFRLKK--SNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPIVVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQKQYEFVCRAIIYYY 3178
            + STD+  D D  +++     + +YGFT++   + KSP+I+  +G NT AD CFP+L  GDQ+I IN E  D LT DE+  IIK++      +++ L V+P  Y+         NT E  D                  S P +   NL +  + ++K LE+S+++   +Q FE +Y++K GLTM EAKK+EN +KNRY+DI PYDQTR+++KN   SDYINA+II ++I    ++  + KYIA+QGP++ TS DF  M WE  + L+VMLT L E+GR KC+KYWP   ET++     QI C  E+  +   F +R+  + +  S E R+  H+QYI+WPDH VP    +F+ F+  +R+ RS   EPIVVHCSAGIGRTGV+ITM+ A+ ++E ++  +++ I++ +R+QRA +IQ+  Q++FVC AII  Y
Sbjct:  593 SHSTDRFYDNDLMIKLRCDR-NRRYGFTVRSTSERKSPIIINFIGKNTPADMCFPRLNVGDQLISINGENVDHLTQDEVISIIKNSSESGCGDII-LKVRPNNYM------VECNTVESSDWDFSITENGSESKSSIISSKPDILSSNL-DPFKESLKFLENSVENDDILQQFESVYRKKPGLTMMEAKKTENFSKNRYRDISPYDQTRVILKNNGSSDYINASIINMQIN---DNGMINKYIAAQGPLLRTSEDFWQMCWEQNTYLIVMLTALSEQGRPKCHKYWPQIYETIEFG-DFQISCLVEEYSEDGGFAIRDLMVYRTVSKEERRVQHMQYISWPDHGVPAVHYEFINFVYKVRKFRSGHFEPIVVHCSAGIGRTGVLITMETAMCFIEARKPINLVDILQTMRDQRASMIQTPAQFKFVCEAIIKVY 1013

HSP 2 Score: 223.787 bits (569), Expect = 1.317e-59
Identity = 138/394 (35.03%), Postives = 214/394 (54.31%), Query Frame = 2 
Query:  137 MFNKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLDSVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMKTFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAGCSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPEDAELQYINTAKQLSKYGCDLYTCQLMDDQ-VQFGLNAHGITVYNSPDIKNTYIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSVIHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDP---KQIERGGSIRRSQSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPS 1306
            M   SY VAA E   K    + +K +V LLD   E F L  ++ G   LD + D LE+LERD+FG+QYKD     +  +YKWL   K ++KQ+ T      F+FRV+F P    QM+E YTRY LF Q+K+DIF+ ++ C++D+   L   +LQ+ELGDY+    K+ Y+ EFRF+ +Q    E  ++  H  +K   P  AE +Y+N A +L  YG D++    +D + VQ G ++ G +V+ +   K  ++  W+SI K+  K K   +++  +  +    +   S          S +++        +V  +    K  W N ++ H+FFRVK P    QI +  +  +  +FF IS+   F GRRT+P + DI++R+R  DR+F R PS
Sbjct:    1 MLGGSYYVAAREEY-KHHASNDLKCQVVLLDGNVEFFTLQKKSCGHCLLDLIFDTLELLERDFFGLQYKDSHPS-SGKYYKWLNGAKSIKKQL-TGSQPYIFHFRVKFYPNNPSQMKEEYTRYLLFLQLKKDIFDERLHCNQDMVAILGSYALQAELGDYNPQQHKSGYISEFRFVKNQTPVLELKISDLHMKMKNFSPTKAEREYLNIASELDYYGVDIFNALTLDKEIVQIGPSSLGFSVFKNK--KRMHLFLWSSIFKISFKKKKITIQIKSTHFVDQFKNNEESN-------KSSPLMYT-------YVLSSSPLCKTLWQNCVDYHTFFRVKVPPNNSQI-KANTKSKGSNFFGISITPAFCGRRTMPTIEDIQKRSRTTDRTFIRTPS 374
The following BLAST results are available for this feature:
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PTPN44.507e-9843.80protein tyrosine phosphatase non-receptor type 4 [... [more]
PTPN32.046e-9541.48protein tyrosine phosphatase non-receptor type 3 [... [more]
PTPN35.124e-9541.48protein tyrosine phosphatase non-receptor type 3 [... [more]
PTPN37.284e-9441.48protein tyrosine phosphatase non-receptor type 3 [... [more]
PTPN31.941e-5638.06protein tyrosine phosphatase non-receptor type 3 [... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ptp-11.075e-9940.96Tyrosine-protein phosphatase 1 [Source:UniProtKB/... [more]
ptp-11.075e-9940.96Tyrosine-protein phosphatase 1 [Source:UniProtKB/... [more]
ptp-11.075e-9940.96Tyrosine-protein phosphatase 1 [Source:UniProtKB/... [more]
ptp-11.032e-9840.96Tyrosine-protein phosphatase 1 [Source:UniProtKB/... [more]
ptp-11.032e-9840.96Tyrosine-protein phosphatase 1 [Source:UniProtKB/... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ptpmeg5.503e-6439.76gene:FBgn0261985 transcript:FBtr0306563[more]
Ptpmeg5.503e-6439.76gene:FBgn0261985 transcript:FBtr0306559[more]
Ptpmeg5.503e-6439.76gene:FBgn0261985 transcript:FBtr0306560[more]
Ptpmeg5.503e-6439.76gene:FBgn0261985 transcript:FBtr0306561[more]
Ptpmeg5.503e-6439.76gene:FBgn0261985 transcript:FBtr0306562[more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ptpn4b2.039e-10040.94protein tyrosine phosphatase non-receptor type 4b ... [more]
ptpn4a4.908e-9941.04protein tyrosine phosphatase non-receptor type 4a ... [more]
ptpn4a8.731e-9940.09protein tyrosine phosphatase non-receptor type 4a ... [more]
ptpn4a1.149e-9840.09protein tyrosine phosphatase non-receptor type 4a ... [more]
ptpn4a1.307e-9840.09protein tyrosine phosphatase non-receptor type 4a ... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mon22.413e-9140.60MON2 homolog, regulator of endosome-to-Golgi traff... [more]
mon23.429e-8837.93MON2 homolog, regulator of endosome-to-Golgi traff... [more]
mon27.880e-8837.93MON2 homolog, regulator of endosome-to-Golgi traff... [more]
mon22.104e-8240.97MON2 homolog, regulator of endosome-to-Golgi traff... [more]
mon23.151e-8240.97MON2 homolog, regulator of endosome-to-Golgi traff... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ptpn49.040e-9843.41protein tyrosine phosphatase, non-receptor type 4 ... [more]
Ptpn33.312e-9140.61protein tyrosine phosphatase, non-receptor type 3 ... [more]
Ptpn123.405e-5338.26protein tyrosine phosphatase, non-receptor type 12... [more]
Ptpn201.446e-5139.34protein tyrosine phosphatase, non-receptor type 20... [more]
Ptpn221.749e-4940.15protein tyrosine phosphatase, non-receptor type 22... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P29074|PTN4_HUMAN2.165e-9743.80Tyrosine-protein phosphatase non-receptor type 4 O... [more]
sp|Q9WU22|PTN4_MOUSE6.324e-9743.41Tyrosine-protein phosphatase non-receptor type 4 O... [more]
sp|P26045|PTN3_HUMAN3.498e-9341.48Tyrosine-protein phosphatase non-receptor type 3 O... [more]
sp|P28191|PTP1_CAEEL3.908e-9340.96Tyrosine-protein phosphatase 1 OS=Caenorhabditis e... [more]
sp|A2ALK8|PTN3_MOUSE2.317e-9040.61Tyrosine-protein phosphatase non-receptor type 3 O... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A498ND051.761e-15533.40Tyrosine-protein phosphatase OS=Labeo rohita OX=84... [more]
A0A1D1VE905.995e-15133.07Uncharacterized protein OS=Ramazzottius varieornat... [more]
A0A085M4E36.037e-14531.10Uncharacterized protein OS=Trichuris suis OX=68888... [more]
A0A2A2LK821.908e-14029.65Uncharacterized protein OS=Diploscapter pachys OX=... [more]
A0A1B0AE306.651e-12128.94Tyrosine-protein phosphatase OS=Glossina pallidipe... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ptpn4a7.485e-10039.74protein tyrosine phosphatase non-receptor type 4a ... [more]
ptpn4b1.361e-9541.01protein tyrosine phosphatase non-receptor type 4b ... [more]
ptpn35.799e-9240.05protein tyrosine phosphatase non-receptor type 3 [... [more]
ENSAMXT00000036551.11.199e-5336.43protein tyrosine phosphatase non-receptor type 12 ... [more]
ENSAMXT00000016537.21.210e-5336.43protein tyrosine phosphatase non-receptor type 12 ... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000001312.11.598e-9040.05pep scaffold:Pmarinus_7.0:GL477231:34421:73675:-1 ... [more]
PTPN123.707e-4936.43protein tyrosine phosphatase non-receptor type 12 ... [more]
ENSPMAT00000009934.14.293e-4529.71pep scaffold:Pmarinus_7.0:GL479331:74:24469:1 gene... [more]
ptprk6.337e-4532.31protein tyrosine phosphatase receptor type K [Sour... [more]
ENSPMAT00000000174.12.989e-4435.07pep scaffold:Pmarinus_7.0:GL479793:24808:47889:1 g... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
PTP18.560e-2728.83Phosphotyrosine-specific protein phosphatase; deph... [more]
PTP26.360e-2025.15Nuclear phosphotyrosine-specific phosphatase invol... [more]
PTP32.859e-1235.29Phosphotyrosine-specific protein phosphatase; invo... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO448231.624e-8635.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO383041.994e-5535.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO489492.117e-5032.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO483583.226e-4836.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO339951.376e-4639.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ptpn4a5.379e-9539.45protein tyrosine phosphatase non-receptor type 4 [... [more]
ptpn4a4.417e-9440.88protein tyrosine phosphatase non-receptor type 4 [... [more]
ptpn31.113e-8636.02protein tyrosine phosphatase non-receptor type 3 [... [more]
ptpn32.834e-6431.57protein tyrosine phosphatase non-receptor type 3 [... [more]
ptpn201.014e-5338.29protein tyrosine phosphatase non-receptor type 20 ... [more]
back to top
BLAST of Tyrosine-protein phosphatase non-receptor type vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000023435.10.000e+095.58SMESG000023435.1[more]
SMESG000023435.12.696e-1396.22SMESG000023435.1[more]
SMESG000023435.10.000e+099.35SMESG000023435.1[more]
SMESG000022143.14.031e-9741.94SMESG000022143.1[more]
SMESG000022143.14.811e-9741.94SMESG000022143.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034196 ID=SMED30034196|Name=Tyrosine-protein phosphatase non-receptor type|organism=Schmidtea mediterranea sexual|type=transcript|length=3680bp
TTTTAGGGTCAGTAAATAGCTAATATTTGAAATTTAAAATTACTTAAATA
TATATACGGTAATTATACAAAGTTTTACACGATACTAAATTAATTAAAAG
TAGCAGAATCGTCGTTATTTTTTATTATTTTAGTAAATGTTTAATAAAAG
TTATAATGTGGCTGCCGCTGAAAGAGCGAACAAAGAATTATTGTATTCCC
ATATCAAAGTGAAAGTAAAACTATTGGACGAAACATCTGAAATATTTAAT
TTAAGTACTGAAGCAACAGGGTTTAATTTTCTAGATTCTGTGTGTGACTG
TTTAGAAATTTTGGAAAGAGATTATTTTGGAATTCAATACAAAGACGACG
ATGACAAACTAAATAATACATTTTATAAATGGTTGAAGTTAAATAAATTG
GTAAGAAAGCAAATAAAAACCGATATTTCAATGAAAACCTTTTATTTCCG
TGTTCGTTTTATTCCAGCAGAAATCATGCAAATGCAAGAAAGTTATACGA
GATATCAGTTATTTCAGCAAATAAAACAAGATATATTCAATAATAAAATT
AGTTGCTCAAAAGACATTGCCGTTCAACTAGCCGGTTGTTCATTACAATC
CGAATTGGGAGATTATCATTCATCGACAATGAAGACTAATTATGTAGGAG
AATTTCGGTTTATTCCTGACCAAAACGCTACATTCGAATCAGATGTTGCC
AGTTTTCATAAAACACTGAAGGGTTTAAAGCCCGAAGATGCAGAATTACA
ATACATAAACACTGCGAAGCAATTGTCTAAATACGGATGTGATCTGTATA
CTTGTCAGCTAATGGATGACCAAGTTCAATTTGGTCTTAATGCTCATGGA
ATAACTGTCTACAACTCACCAGATATTAAAAATACTTATATTATACCTTG
GAATTCGATAGAAAAAGTTTTAAATAAAAACAAGTGCTTTCTTGTTAAAC
TGCTGCTTAGCCAACCAATTGTTGCAATGTTAGATGGTGGGCATTCTCAA
TCAATGCAACGTAGTGTTAAAGCCGATTCTTCTGTCATTCATCAAAAAAT
GAGTTCGGGTTTGAAGTTTGTCTTTCCAACGAAAGACGCTGCTAAAGAGG
CTTGGTGTAATAGTATTGAAATGCATTCATTCTTTCGAGTCAAAGATCCA
AAACAAATCGAACGAGGTGGATCAATACGTAGATCTCAGTCGTTTTTCAA
AATTTCACTTGCAAATATGTTCAGTGGTCGTCGAACATTGCCAGAACTTC
TTGACATAAGACGCAGAAATCGGTTGATGGACCGATCCTTTGCACGTATA
CCCAGTAAGCGCTATAATCGACGAAATACGCCTGGTGGGGAGAGACAGTC
AATTGTTAGTGCAGAAACAAATCGGCCTACGGGAATTGTATATGGGAAAA
GTAATCCAACTTCAAACAATCCCTCAAATTATGTTAAACCAAAATTGAAT
GATAAGAAAAAAACAGTGGAATCCAACGTAAGTGAGTCTTCAGATGAATC
TGATCATCATGATCTCGAAGTTGAACCCGGGGCATTTCGAAATAAATCTA
GTGTCACACAGAGTGTTCGAGTTCCCAAAGCATCAACTGCAAAAGGTTTT
CAAAAACATCCTGTTATTCACTCTTCAATGCCCAGACAGAAAGTTACAGG
AACGATTTCTAAATCTCAAACATCGATAAATCAAGAATTAACTCCAACTG
ATCCAAATATTCCCGATATCATGTCTAGATCAATTGGGAGAAACGAACAA
AACAAACCAGGAAATAATGTTTCTCTAAAGGAACAAAATATTCTATTTGA
AACCAAAATGAAAACATCAAAAAGTCCAAAAGCATCGAGATATTCTATAC
AAGAATTAAAGTCTAATAAAGCCTCAACTCAACCTAATGCTAAATTATCC
GGTTCTATGTCATCAATGAAAAATGCTTTATCAAATTCGACATCGACAAT
GACTCAGTCGACTGACAAACTGATCGACACCGATACGCGAGTCGAGATAG
CCATGAGACCCATAGACTCTAAATATGGGTTCACGATTAAAGGAGGTTGT
GACTCGAAGTCTCCGGTCATTGTTACAAAAGTCGGCCCAAATACGGCGGC
TGATCAATGCTTTCCAAAACTCTGCGAAGGTGATCAAATTATAAAAATCA
ATGACGAATTCGCTGATGAACTAACAAATGATGAAATAAAAGAAATTATA
AAATCAACTGGGAGCATGAAAAAGGATAACGTACTCAACCTAGTTGTCAA
ACCTAGATTATATCTCAATGTTGATGAACATACATCTTCAAATAATACTG
AAGAAGACGAAGATTCCTTGCCCCCTCTTCCCCGGAAAAATTTGGTTAAT
GATATTCGTTTGACAATAAAATCTTTGGAAGATTCTCTCAAAGATGGAAG
TGCTGTTCAAGTGTTTGAGAAACTCTATAAACAGAAGCAAGGCCTGACAA
TGAATGAAGCGAAAAAATCAGAAAATATTAATAAAAATCGTTACAAAGAT
ATACTTCCGTATGATCAAACAAGAATAGTTATCAAGAACAGTGACTATAT
AAATGCCAATATAATTAAGGTTGAAATTCCTAAATCACCGAACTCGACCA
CAGTTTTTAAATACATCGCAAGTCAAGGACCAATGGTCCATACTTCCAGT
GATTTTATAACAATGATTTGGGAAAATAAATCGGAATTAGTTGTTATGCT
AACTGATCTTCTAGAAAAGGGCCGTTCAAAATGCTACAAATATTGGCCTG
ATCAAGGCGAGACTTTAAAATTGCAACATGGTCTTCAAATATTTTGTGAA
TCAGAAAAATGTATAGATACGTTTGTTCTAAGAGAATTCAGGTTGAAAAA
GTCAAATGAAACTCGAAAGTTTACTCATCTGCAATACATTAATTGGCCTG
ATCATGATGTTCCAATTAAGATGGATGATTTTTTGGCTTTCATGAAAATG
ATAAGACAAATAAGATCTTCGAGATCCGAACCAATCGTCGTACATTGCTC
GGCTGGCATTGGGCGTACTGGTGTTGTTATTACTATGGACATAGCAATAT
CATATTTGGAAATGAAACAGTCTTTTTCCGTTTTATCTATTGTTAAAGAT
ATTAGGAATCAAAGAGCAATGCTAATTCAATCTCAAAAACAGTACGAATT
CGTTTGTCGAGCAATTATTTATTATTATAATAATATATGCAAATAGAAAA
TTTGATCTGCGAATTTTTGGATTTAATTAAATGGAATTTTGCAGCATCTT
CCTTTCCATATCTCTTTTTTGTTGTGTTTCTGTTATTCTGCCATTAGTAT
TATGTAAATAAGTCGATCGGCGTATTTTGTTTTTATGAATTTTTCAAAGT
GATTGTTTATAATCTTACAGACATTCTGTGATAAATTGGTCGGTTCTGTT
TGGATTGACTTGAAACGATAATTCAACAATGTAAAGTTGTCATTGTTTTT
TTTATTTGTAATACTTTCGTCATTCTTATCTGCCTTTTACTAAATCAGCT
ATAGATTTATTTCTCATTTCGGATTAATATCTATCTTTAATTATCAATTT
TTATTAAAATTCATTATCTTTTAACTATTTTTACCTGAAAAATATGATGG
AAAATTTATTAACAATTGTTTTTGTTTTCGTCCTCGCGTCTCTTGATGTT
TATGAAATTGTCGTTTTGTATATTACGCTC
back to top

protein sequence of SMED30034196-orf-1

>SMED30034196-orf-1 ID=SMED30034196-orf-1|Name=SMED30034196-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1020bp
MFNKSYNVAAAERANKELLYSHIKVKVKLLDETSEIFNLSTEATGFNFLD
SVCDCLEILERDYFGIQYKDDDDKLNNTFYKWLKLNKLVRKQIKTDISMK
TFYFRVRFIPAEIMQMQESYTRYQLFQQIKQDIFNNKISCSKDIAVQLAG
CSLQSELGDYHSSTMKTNYVGEFRFIPDQNATFESDVASFHKTLKGLKPE
DAELQYINTAKQLSKYGCDLYTCQLMDDQVQFGLNAHGITVYNSPDIKNT
YIIPWNSIEKVLNKNKCFLVKLLLSQPIVAMLDGGHSQSMQRSVKADSSV
IHQKMSSGLKFVFPTKDAAKEAWCNSIEMHSFFRVKDPKQIERGGSIRRS
QSFFKISLANMFSGRRTLPELLDIRRRNRLMDRSFARIPSKRYNRRNTPG
GERQSIVSAETNRPTGIVYGKSNPTSNNPSNYVKPKLNDKKKTVESNVSE
SSDESDHHDLEVEPGAFRNKSSVTQSVRVPKASTAKGFQKHPVIHSSMPR
QKVTGTISKSQTSINQELTPTDPNIPDIMSRSIGRNEQNKPGNNVSLKEQ
NILFETKMKTSKSPKASRYSIQELKSNKASTQPNAKLSGSMSSMKNALSN
STSTMTQSTDKLIDTDTRVEIAMRPIDSKYGFTIKGGCDSKSPVIVTKVG
PNTAADQCFPKLCEGDQIIKINDEFADELTNDEIKEIIKSTGSMKKDNVL
NLVVKPRLYLNVDEHTSSNNTEEDEDSLPPLPRKNLVNDIRLTIKSLEDS
LKDGSAVQVFEKLYKQKQGLTMNEAKKSENINKNRYKDILPYDQTRIVIK
NSDYINANIIKVEIPKSPNSTTVFKYIASQGPMVHTSSDFITMIWENKSE
LVVMLTDLLEKGRSKCYKYWPDQGETLKLQHGLQIFCESEKCIDTFVLRE
FRLKKSNETRKFTHLQYINWPDHDVPIKMDDFLAFMKMIRQIRSSRSEPI
VVHCSAGIGRTGVVITMDIAISYLEMKQSFSVLSIVKDIRNQRAMLIQSQ
KQYEFVCRAIIYYYNNICK*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005856cytoskeleton
Vocabulary: molecular function
TermDefinition
GO:0008092cytoskeletal protein binding
GO:0004725protein tyrosine phosphatase activity
GO:0005515protein binding
GO:0016791phosphatase activity
GO:0004721phosphoprotein phosphatase activity
GO:0016787hydrolase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR036034PDZ_sf
IPR019749Band_41_domain
IPR000242PTPase_domain
IPR001478PDZ
IPR018980FERM_PH-like_C
IPR003595Tyr_Pase_cat
IPR018979FERM_N
IPR019748FERM_central
IPR014352FERM/acyl-CoA-bd_prot_sf
IPR011993PH-like_dom_sf
IPR029021Prot-tyrosine_phosphatase-like
IPR019747FERM_CS
IPR016130Tyr_Pase_AS
IPR000299FERM_domain
IPR000387TYR_PHOSPHATASE_dom
IPR029071Ubiquitin-like_domsf
Vocabulary: biological process
TermDefinition
GO:0006470protein dephosphorylation
GO:0016311dephosphorylation
GO:0035335peptidyl-tyrosine dephosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000242PTP type protein phosphatasePRINTSPR00700PRTYPHPHTASEcoord: 329..349
score: 52.16
coord: 306..313
score: 73.46
coord: 452..470
score: 67.37
coord: 413..430
score: 42.32
coord: 499..509
score: 40.75
coord: 483..498
score: 29.34
IPR000242PTP type protein phosphataseSMARTSM00194PTPc_3coord: 258..518
e-value: 8.8E-105
score: 364.1
IPR000242PTP type protein phosphatasePFAMPF00102Y_phosphatasecoord: 283..514
e-value: 2.8E-72
score: 243.1
IPR000242PTP type protein phosphatasePROSITEPS50055TYR_PHOSPHATASE_PTPcoord: 259..516
score: 45.231
IPR003595Protein-tyrosine phosphatase, catalyticSMARTSM00404ptp_7coord: 414..515
e-value: 2.2E-33
score: 126.9
IPR001478PDZ domainSMARTSM00228pdz_newcoord: 131..211
e-value: 1.5E-8
score: 44.4
IPR001478PDZ domainPFAMPF00595PDZcoord: 127..206
e-value: 4.5E-12
score: 46.2
IPR001478PDZ domainPROSITEPS50106PDZcoord: 121..196
score: 13.752
IPR036034PDZ superfamilyGENE3DG3DSA:2.30.42.10coord: 105..210
e-value: 3.7E-17
score: 64.2
IPR036034PDZ superfamilySUPERFAMILYSSF50156PDZ domain-likecoord: 129..208
IPR029021Protein-tyrosine phosphatase-likeGENE3DG3DSA:3.90.190.10coord: 216..520
e-value: 1.2E-95
score: 322.4
IPR029021Protein-tyrosine phosphatase-likeSUPERFAMILYSSF52799(Phosphotyrosine protein) phosphatases IIcoord: 248..520
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 60..91
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..23
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..24
NoneNo IPR availablePANTHERPTHR45706:SF4TYROSINE-PROTEIN PHOSPHATASEcoord: 45..520
NoneNo IPR availablePANTHERPTHR45706FAMILY NOT NAMEDcoord: 45..520
NoneNo IPR availableCDDcd00992PDZ_signalingcoord: 121..208
e-value: 8.82373E-16
score: 70.2882
NoneNo IPR availableCDDcd14600PTPc-N3coord: 246..517
e-value: 7.08718E-100
score: 300.613
IPR016130Protein-tyrosine phosphatase, active sitePROSITEPS00383TYR_PHOSPHATASE_1coord: 455..465
IPR000387Tyrosine specific protein phosphatases domainPROSITEPS50056TYR_PHOSPHATASE_2coord: 433..507
score: 20.234