Receptor-type tyrosine-protein phosphatase beta

Query: 2028 NVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSV---LSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNES-----VIYNDNITSTT----VTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIP--DAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN---LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVT-------VGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKH----VSEATNTAITHLLPMD---------------SKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQA--IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            N  N   E+++L+  T Y++ +T F+   +++     +S + +  T E  P      ++F+ +    T  + T+ PP + NG I  Y      E       I+N +I   T    + + E ++    Y   V A  S G G P     I +    P        P  DA  K+ +      T   I +P  ++S++ G I+   ++++ET     GN +     Y N A      +     E   +PP  +   K + N       E YI+G +   ++    D   NGPLK    Y+  FRA    G  T       V  +    +   +  I+ V++ +  II L  AI+   R ++ +      S      I   L +D               ++  +   F ++ E +  ++N +  ++F E+ +    L      +    N AKNRF NIKPY +NRVKL+A      +DYINAS I              C N +IATQGP+         TVGDFWRM+ E     +V LT+  E G+ +C QYWP E N+ +T + +     +  +  +D++I   R   +      ++V Q +  AW +HG P  S  L  +    +A +++    ++VHCSAGVGRTG FI +D  L++ + + D ++IY  +  LR  R  MVQ  +QY F++  I + L   G
Sbjct: 1633 NEENKTIEIKDLEIFTRYSVVITAFTGNISAAYVEGKSSAEMIVTTLESAPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTNTFVIAMLEGLKGGHTYNISVYAVNSAGAG-PKVPMRITMDIKAPARPKTKPTPIYDATGKLLVTS----TTITIRMPICYYSDDHGPIKNVQVLVTETGAQHDGNVTKWYDAYFNKA------RPYFTNEGFPNPPCTEGKTKFSGN------EEIYIIGADNACMIPGNEDKICNGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPQDAEIIDTKLKLDQLITVADLELKDERLTRPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADL--PWNRAKNRFPNIKPYNNNRVKLIADASVPGSDYINASYISG----------YLCPNEFIATQGPL-------PGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWP-EDNKPVTVFGDIVITKLMEDVQIDWTI---RDLKIERHGDCMTVRQCNFTAWPEHGVPENSAPLIHFVKLVRASRAHDTTPMIVHCSAGVGRTGVFIALD-HLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKG 2297          

Query: 2028 NVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSV---LSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNES-----VIYNDNITSTT----VTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIP--DAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN---LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVT-------VGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVS--------------------------EATNTAITHLL-------PMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQA--IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            N  N   E+++L+  T Y++ +T F+   +++     +S + +  T E  P      ++F+ +    T  + T+ PP + NG I  Y      E       I+N +I   T    + + E ++    Y   V A  S G G P     I +    P        P  DA  K+ +      T   I +P  ++S++ G I+   ++++ET     GN +     Y N A      +     E   +PP  +   K + N       E YI+G +   ++    D   NGPLK    Y+  FRA    G  T       V  +    +   +  I+ V++ +  II L  AI+   R ++ +                             E  +  +T LL       P+  KS     F ++ E +  ++N +  ++F E+ +    L      +    N AKNRF NIKPY +NRVKL+A      +DYINAS I              C N +IATQGP+         TVGDFWRM+ E     +V LT+  E G+ +C QYWP E N+ +T + +     +  +  +D++I   R   +      ++V Q +  AW +HG P  S  L  +    +A +++    ++VHCSAGVGRTG FI +D  L++ + + D ++IY  +  LR  R  MVQ  +QY F++  I + L   G
Sbjct: 1591 NEENKTIEIKDLEIFTRYSVVITAFTGNISAAYVEGKSSAEMIVTTLESAPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTNTFVIAMLEGLKGGHTYNISVYAVNSAGAG-PKVPMRITMDIKAPARPKTKPTPIYDATGKLLVTS----TTITIRMPICYYSDDHGPIKNVQVLVTETGAQHDGNVTKWYDAYFNKA------RPYFTNEGFPNPPCTEGKTKFSGN------EEIYIIGADNACMIPGNEDKICNGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPQDAEIIDTKLKLDQLITVADLELKDERLTRLLSYRKSIKPISKKS-----FLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADL--PWNRAKNRFPNIKPYNNNRVKLIADASVPGSDYINASYISG----------YLCPNEFIATQGPL-------PGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWP-EDNKPVTVFGDIVITKLMEDVQIDWTI---RDLKIERHGDCMTVRQCNFTAWPEHGVPENSAPLIHFVKLVRASRAHDTTPMIVHCSAGVGRTGVFIALD-HLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKG 2264          

Query: 2955 IVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQD--SNGRLLDDFREIKELAVKLERQKV----------------IMFT------EGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVF----NVSMDEKEISVTQLHMLAWKDHGCPT-TSEFLAFYSAYRKARQSNQA-IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQA 3992
            ++G  +AV  IIC+ IAI     YK+  H     +   T  L +++   A H   +  E  + +  + G L      I ++A   ER K                   FT      E N  KNR++N+  Y H+RV L     +  +DYINA+ +              C N YIATQGP+ E       T GDFWRM+ E     IV +TR+EE  + KC QYWP    +   +      I V +  +++ + F  R F    N S +++E  V Q    AW DHG P   + FLAF    +     +   IVVHCSAGVGRTG FI+ID  L RI K +  +++Y ++  +R  R  MVQTE QY F    IHE L++A
Sbjct:  855 VIGPVLAVVFIICIVIAILL---YKKKPHSKRKDSEPRTKCL-LNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYR----------CQNAYIATQGPLPE-------TFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGF------IQVTLLDTIELATFCVRTFSLHKNGSSEKRE--VRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERI-KPEKTVDVYGHVTLMRSQRNYMVQTEDQYSF----IHEALLEA 1201          

Query: 3237 NDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ---SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            N  KNR  NI PY+  RV L     +  +DYINAS I     Q            YIATQGP+ E  E       DFWRM+ ENN  ++V LT++ E G+EKC QYWP E + +  Y+  D      M        ++ R F V+   D +  +V Q     W + G P + E F+ F     K ++    +  I VHCSAGVGRTG FI +   L R ++ +  ++I+  +  LR  R  MVQTE +Y F Y    EYL
Sbjct: 1258 NKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQ----------KAYIATQGPLAETTE-------DFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ------YILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLER-MRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYL 1493          

Query: 2958 VGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNT----------AITHLLPMDSKSPAAHEFHENY--EFMKQDSNGRLLDDFREIKE-----LAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSI---FVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQ----AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEY 3980
            V V+++  ++I   I + +++R+K+ K     +N+               +P+ ++SP+ +  +     + ++++ N R+ DD +  +E      A  ++        E N  KNR+ NI PY H+RV L     +  +DYINAS I       EK       N +IA QGP       K +TV DFWRMI E N   IV +T ++E  + KC+QYWP   +Q    Y        ++   +DY++    +++V +++  + +  +TQ H  +W D G P T   +      +K +  N     AIVVHCSAGVGRTGTF++ID  L  ++  + ++++Y  +  +R  RCQMVQT+ QY FIY  + E+
Sbjct:  146 VMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQ---EK-------NKFIAAQGP-------KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP---DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTP--IGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLD-MMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH 492          

Query: 3126 YEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNV--SMDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ--SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            Y  +   SN  L ++F+++  + ++ ++ +       N  KNR   I PY+ NRV +  K      DY+NAS I   + Q +          YIA+QGP+         T+ DFWRMI E   C IV LT +EE G+EKC+QYWP++    +  Y +   I VE+    +   +  R   V  + + K   + Q H   W + G P+  +  ++  +A +K +Q   N  I VHCSAG GRTGTF  +   L R+ K +  ++++  + +LR  R  MVQT  QY F Y V+ EY+
Sbjct:  513 YNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNL-PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFI-DGYRQKDS---------YIASQGPL-------LHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD---GLVSYGD---ITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERV-KAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 783          

Query: 2958 VGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNT----------AITHLLPMDSKSPAAHEFHENY--EFMKQDSNGRLLDDFREIKE-----LAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSI---FVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQ----AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEY 3980
            V V+++  ++I   I + +++R+K+ K     +N+               +P+ ++SP+ +  +     + ++++ N R+ DD +  +E      A  ++        E N  KNR+ NI PY H+RV L     +  +DYINAS I       EK       N +IA QGP       K +TV DFWRMI E N   IV +T ++E  + KC+QYWP   +Q    Y        ++   +DY++    +++V +++  + +  +TQ H  +W D G P T   +      +K +  N     AIVVHCSAGVGRTGTF++ID  L  ++  + ++++Y  +  +R  RCQMVQT+ QY FIY  + E+
Sbjct:  146 VMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQ---EK-------NKFIAAQGP-------KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP---DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTP--IGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLD-MMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH 492          

Query: 3126 YEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNV--SMDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ--SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            Y  +   SN  L ++F+++  + ++ ++ +       N  KNR   I PY+ NRV +  K      DY+NAS I   + Q +          YIA+QGP+         T+ DFWRMI E   C IV LT +EE G+EKC+QYWP++    +  Y +   I VE+    +   +  R   V  + + K   + Q H   W + G P+  +  ++  +A +K +Q   N  I VHCSAG GRTGTF  +   L R+ K +  ++++  + +LR  R  MVQT  QY F Y V+ EY+
Sbjct:  513 YNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNL-PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFI-DGYRQKDS---------YIASQGPL-------LHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD---GLVSYGD---ITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERV-KAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 783          

Query: 3111 EFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEG--NDAKNRFSNIKPYKHNRVKLLAKN-----DYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQL----HMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKED---DRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            +F ++   M  DS+ R  +++  ++ + V     + +  +E   N  KNRF+NI  Y H+RVKL   N     DYINA+ +    + S +E        +IA QGP+   R+        FW+M  E     I+ LT+  E G++KC QYWP   N  + Y      I V + +  ++  FV R   +     +  VT+     H +AW D G P+      +F   +  +      N   +VHCSAGVGR+GTFI ID    R+L+     D I+++  +  +R  RCQMVQ E QY FI+  I + L
Sbjct:  104 DFADHVRLMSADSDFRFSEEYDMMRNVGVG----QSVAASELPINRPKNRFTNIPSYDHSRVKLSNPNNIEGGDYINANYVPG--FSSRRE--------FIAAQGPLPTTRD-------HFWQMTWEQQCPAIIALTKCVEKGRDKCHQYWPDHENVPVLYGD----IEVTIVAEKEFDEFVIRDIRLEKSGPDGRVTRFVRHWHYMAWPDFGAPSHPNGIIQFSRMFRHHLPHSPHNAPTIVHCSAGVGRSGTFISID----RLLQSSSFGDPIDVFGTVCEMRYERCQMVQNEQQYIFIHYCILQVL 383          

Query: 3156 RLLDDFREIKELAVKLERQKVIMFTEGND------AKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNV------------------SMDEKEISVTQLHMLAWKD-HGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            RLL D     E  V L R +    T   D      A NR+S+I PY H  V+L    DYINAS +     Q E +     +  +IATQGPI        +TV DFWRMI++ +V  IV L + +E   +KC +YWP+ +  K   Y E   ++V++   ++   +V R F+V                  S  +  + V+Q     WKD  G P  + FL F    R  RQ    IVVHCSAG+GRTG FI  D  +SR  + +  I+I++ +   R+ R  MV T  QY  IY +I EYL
Sbjct:  139 RLLQD-----EFLV-LSRTEARRLTRSTDRATRHAAANRYSDIVPYDHTLVEL-DTGDYINASFV-----QGESD-----ATRWIATQGPIDSGECIGKETVSDFWRMIVQYDVACIVMLGQHQEDFVQKCGEYWPSAMG-KTERYGE---VDVKLVCELEEKTWVHREFDVSPTSSYSSSTKSSRKSRASRQQSHMKVSQWQYKEWKDTGGAPRIANFLEFLLQVR-GRQYTSPIVVHCSAGIGRTGVFICTDNVISR-FESEGIIDIFSEVNRSRQQRPSMVYTVKQYECIYDIIGEYL 416          

Query: 3111 EFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEG--NDAKNRFSNIKPYKHNRVKLLAKN-----DYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQL----HMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKED---DRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            +F ++   M  DS+ R  +++  ++ + V     + +  +E   N  KNRF+NI  Y H+RVKL   N     DYINA+ +    + S +E        +IA QGP+   R+        FW+M  E     I+ LT+  E G++KC QYWP   N  + Y      I V + +  ++  FV R   +     +  VT+     H +AW D G P+      +F   +  +      N   +VHCSAGVGR+GTFI ID    R+L+     D I+++  +  +R  RCQMVQ E QY FI+  I + L
Sbjct: 1056 DFADHVRLMSADSDFRFSEEYDMMRNVGVG----QSVAASELPINRPKNRFTNIPSYDHSRVKLSNPNNIEGGDYINANYVPG--FSSRRE--------FIAAQGPLPTTRD-------HFWQMTWEQQCPAIIALTKCVEKGRDKCHQYWPDHENVPVLYGD----IEVTIVAEKEFDEFVIRDIRLEKSGPDGRVTRFVRHWHYMAWPDFGAPSHPNGIIQFSRMFRHHLPHSPHNAPTIVHCSAGVGRSGTFISID----RLLQSSSFGDPIDVFGTVCEMRYERCQMVQNEQQYIFIHYCILQVL 1335          

Query: 3246 KNRFSNIKPYKHNRVKLLAK--NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEK----EISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRD 4016
            KNR++NI   +  R++L +   NDYINA+ +          + C   N YIATQ P+         T  DFW MI +    +IV +T + E GK KC QYWP++ +   T+ +      V + S    + F  R+ ++ + +     E  V QLH + W DHG P++   L  +  Y     S   +VVHCSAGVGR+G++IL+D  + R L    R+ +  +L ++R+ R ++VQT  QY F +  I + L++ G+ R+  D
Sbjct:  675 KNRYNNIGAIEATRIRLNSPTGNDYINANYV----------DSCNERNAYIATQAPL-------PSTFSDFWSMIWQERSNIIVCITNMVEDGKRKCDQYWPSQQDSPQTFGN----YQVTLVSESTNAHFSHRILDLKIAKAVPAVERKVHQLHFMGWPDHGVPSSVFPLLSFVHYTSDIHSTGPVVVHCSAGVGRSGSYILVD-SMRRHLISFRRLNVQGHLTHMRRQRAKLVQTLEQYIFCHEAIRQ-LIRHGITRVHSD 914          

Query: 3246 KNRFSNIKPYKHNRVKLLAK--NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEK----EISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRD 4016
            KNR++NI   +  R++L +   NDYINA+ +          + C   N YIATQ P+         T  DFW MI +    +IV +T + E GK KC QYWP++ +   T+ +      V + S    + F  R+ ++ + +     E  V QLH + W DHG P++   L  +  Y     S   +VVHCSAGVGR+G++IL+D  + R L    R+ +  +L ++R+ R ++VQT  QY F +  I + L++ G+ R+  D
Sbjct:  629 KNRYNNIGAIEATRIRLNSPTGNDYINANYV----------DSCNERNAYIATQAPL-------PSTFSDFWSMIWQERSNIIVCITNMVEDGKRKCDQYWPSQQDSPQTFGN----YQVTLVSESTNAHFSHRILDLKIAKAVPAVERKVHQLHFMGWPDHGVPSSVFPLLSFVHYTSDIHSTGPVVVHCSAGVGRSGSYILVD-SMRRHLISFRRLNVQGHLTHMRRQRAKLVQTLEQYIFCHEAIRQ-LIRHGITRVHSD 868          

Query: 1923 SSSVTGNNIILTWTF--GEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWA-PPVEKNGKILNYWLTCKN----ESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISET-RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAG-FVTVGF-IERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRN-----KHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTE--GNDAKNRFSNIKPYKHNRVKLLA-----KNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLA-FYSAYRKARQSNQ-AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVI 3971
            ++++T   I L W    GE ++  + +  A  +      T N+  + +L+    YT  V        SSV    + L     T E VP  V  F   +   + I   W+ P  E NG I  + +   N          D  +     + + ++    Y  ++ A T++G+G P   +   +P   P      ++P  + + +  +        I    ++FS+  G ++M+T++++E    N  G    + L  Q+             Y + L    P +A+     P  N   E++ +G     N      NGPLKSGT Y +  RA+T A  F    +    +T  +  S IV ++V + +I+ L + + F  R + N     K      N ++   +   ++      F E+Y  M  DS+ R  ++F E+K +     R +   F +   N  KNRF+NI PY H+R KL        +DYINA+ +   +   E          +I TQGP+   R+       DFWRM  E+N   IV LTR  E G+EKC QYWP   N  +  +  D  I V++ +   Y+ +V   F +    ++  +   H   W D G P   + L  F  A+R    + Q  IVVHCSAGVGR+GTFI +D  L +I    D ++I+  +  +RK R  MVQTE QY  I+  +
Sbjct:  872 ATNITDTEISLRWDLPKGEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVV-VRSGTESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFG-PEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQ-------IRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQS-------------YSVWL----PYQAID-PYYPFENRSVEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVG----RDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPRE----------FIVTQGPLHSTRD-------DFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP---NDTVPVFYGD--IKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQI-NTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCL 1524          

Query: 1923 SSSVTGNNIILTWTF--GEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWA-PPVEKNGKILNYWLTCKN----ESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISET-RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAG-FVTVGF-IERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRN-----KHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTE--GNDAKNRFSNIKPYKHNRVKLLA-----KNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLA-FYSAYRKARQSNQ-AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVI 3971
            ++++T   I L W    GE ++  + +  A  +      T N+  + +L+    YT  V        SSV    + L     T E VP  V  F   +   + I   W+ P  E NG I  + +   N          D  +     + + ++    Y  ++ A T++G+G P   +   +P   P      ++P  + + +  +   + +       ++FS+  G ++M+T++++E    N  G    + L  Q+             Y + L    P +A+     P  N   E++ +G     N      NGPLKSGT Y +  RA+T A  F    +    +T  +  S IV ++V + +I+ L + + F  R + N     K      N ++   +   ++      F E+Y  M  DS+ R  ++F E+K +     R +   F +   N  KNRF+NI PY H+R KL        +DYINA+ +   +   E          +I TQGP+   R+       DFWRM  E+N   IV LTR  E G+EKC QYWP   N  +  +  D  I V++ +   Y+ +V   F +    ++  +   H   W D G P   + L  F  A+R    + Q  IVVHCSAGVGR+GTFI +D  L +I    D ++I+  +  +RK R  MVQTE QY  I+  +
Sbjct:  872 ATNITDTEISLRWDLPKGEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVV-VRSGTESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFG-PEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQIRFRK-------NYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQS-------------YSVWL----PYQAID-PYYPFENRSVEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVG----RDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPRE----------FIVTQGPLHSTRD-------DFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP---NDTVPVFYGD--IKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQI-NTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCL 1524          

Query: 1923 SSSVTGNNIILTWTF--GEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWA-PPVEKNGKILNYWLTCKN----ESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISET-RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAG-FVTVGF-IERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRN-----KHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTE--GNDAKNRFSNIKPYKHNRVKLLA-----KNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLA-FYSAYRKARQSNQ-AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVI 3971
            ++++T   I L W    GE ++  + +  A  +      T N+  + +L+    YT  V        SSV    + L     T E VP  V  F   +   + I   W+ P  E NG I  + +   N          D  +     + + ++    Y  ++ A T++G+G P   +   +P   P      ++P  + + +  +   + +       ++FS+  G ++M+T++++E    N  G    + L  Q+             Y + L    P +A+     P  N   E++ +G     N      NGPLKSGT Y +  RA+T A  F    +    +T  +  S IV ++V + +I+ L + + F  R + N     K      N ++   +   ++      F E+Y  M  DS+ R  ++F E+K +     R +   F +   N  KNRF+NI PY H+R KL        +DYINA+ +   +   E          +I TQGP+   R+       DFWRM  E+N   IV LTR  E G+EKC QYWP   N  +  +  D  I V++ +   Y+ +V   F +    ++  +   H   W D G P   + L  F  A+R    + Q  IVVHCSAGVGR+GTFI +D  L +I    D ++I+  +  +RK R  MVQTE QY  I+  +
Sbjct:  872 ATNITDTEISLRWDLPKGEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVV-VRSGTESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFG-PEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQIRFRK-------NYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQS-------------YSVWL----PYQAID-PYYPFENRSVEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVG----RDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPRE----------FIVTQGPLHSTRD-------DFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP---NDTVPVFYGD--IKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQI-NTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCL 1524          

Query: 1923 SSSVTGNNIILTWTF--GEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWA-PPVEKNGKILNYWLTCKN----ESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISET-RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAG-FVTVGF-IERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRN-----KHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTE--GNDAKNRFSNIKPYKHNRVKLLA-----KNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLA-FYSAYRKARQSNQ-AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVI 3971
            ++++T   I L W    GE ++  + +  A  +      T N+  + +L+    YT  V        SSV    + L     T E VP  V  F   +   + I   W+ P  E NG I  + +   N          D  +     + + ++    Y  ++ A T++G+G P   +   +P   P      ++P  + + +  +        I    ++FS+  G ++M+T++++E    N  G    + L  Q+             Y + L    P +A+     P  N   E++ +G     N      NGPLKSGT Y +  RA+T A  F    +    +T  +  S IV ++V + +I+ L + + F  R + N     K      N ++   +   ++      F E+Y  M  DS+ R  ++F E+K +     R +   F +   N  KNRF+NI PY H+R KL        +DYINA+ +   +   E          +I TQGP+   R+       DFWRM  E+N   IV LTR  E G+EKC QYWP   N  +  +  D  I V++ +   Y+ +V   F +    ++  +   H   W D G P   + L  F  A+R    + Q  IVVHCSAGVGR+GTFI +D  L +I    D ++I+  +  +RK R  MVQTE QY  I+  +
Sbjct:  872 ATNITDTEISLRWDLPKGEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVV-VRSGTESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFG-PEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQ-------IRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQS-------------YSVWL----PYQAID-PYYPFENRSVEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVG----RDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPRE----------FIVTQGPLHSTRD-------DFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP---NDTVPVFYGD--IKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQI-NTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCL 1524          

Query: 1923 SSSVTGNNIILTWTF--GEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWA-PPVEKNGKILNYWLTCKN----ESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISET-RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAG-FVTVGF-IERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRN-----KHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTE--GNDAKNRFSNIKPYKHNRVKLLA-----KNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLA-FYSAYRKARQSNQ-AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVI 3971
            ++++T   I L W    GE ++  + +  A  +      T N+  + +L+    YT  V        SSV    + L     T E VP  V  F   +   + I   W+ P  E NG I  + +   N          D  +     + + ++    Y  ++ A T++G+G P   +   +P   P      ++P  + + +  +        I    ++FS+  G ++M+T++++E    N  G    + L  Q+             Y + L    P +A+     P  N   E++ +G     N      NGPLKSGT Y +  RA+T A  F    +    +T  +  S IV ++V + +I+ L + + F  R + N     K      N ++   +   ++      F E+Y  M  DS+ R  ++F E+K +     R +   F +   N  KNRF+NI PY H+R KL        +DYINA+ +   +   E          +I TQGP+   R+       DFWRM  E+N   IV LTR  E G+EKC QYWP   N  +  +  D  I V++ +   Y+ +V   F +    ++  +   H   W D G P   + L  F  A+R    + Q  IVVHCSAGVGR+GTFI +D  L +I    D ++I+  +  +RK R  MVQTE QY  I+  +
Sbjct:  872 ATNITDTEISLRWDLPKGEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVV-VRSGTESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFG-PEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQ-------IRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQS-------------YSVWL----PYQAID-PYYPFENRSVEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVG----RDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPRE----------FIVTQGPLHSTRD-------DFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP---NDTVPVFYGD--IKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQI-NTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCL 1524          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTC----------KNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVY---EIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN--LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAG-FVTVGFIER-KTAVNKIST-----IVGVSVAVFVIICLSIAIYFIIRYKRNKHVS--------------------------EATNTAITHLL-------PMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYRKAR-QSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            P   ++   + +  T +  T++PP E NG I  Y +             + SVI N N T T +   + ++    Y+ +++A    G+G    S + +                A++   + ++   T   I +P   F+++ G IQ   +++SE      GN S          +       T  Y   +  L+P  PK + + +++ K       Y++G +   L   ++   NGPLK  T Y+  FRA    G F    + ++ +TA +++ T     I+GV ++ F+ + L + IY  ++  R K                             E     I  LL       P+  KS     F ++ E +  + N +  ++F E+ +L   L      +    N +KNRF+NIKPY ++RVKLL++     +DYINAS +              C N +IATQGP+         TV DFWRMI E     IV LT+  E G+ +C QYWP E N+ +T +++     +  +   D+++   R   V      + V   +  +W +HG P ++S  + F  A R  R   N  IVVHCSAGVGRTG FI +D  L + L++ + ++IY  +  LR  R  MVQ  +QY F++    + L   G
Sbjct: 1648 PPKNVTLTVIPEEVTRVYVTFSPPDEPNGNISAYRVDIYRNGQLDFFINSLSVISNPNNTMTAII--DGLKGGFNYSIRIAAVNGAGFGPS--SEVHVTTGVKAPPKPKKTPRAALNSAGVIISTSKT-ITIEMPECFFTDDHGPIQKVQVIVSEPAVMDYGNLS---------NWKSVFLHPTAPYLTDDGFLNPECPKNSERMSSSTKT------YVIGEDEGCLSEDAETLCNGPLKPKTHYVFKFRATNIRGQFTDSEYSDKVRTADDRLLTRDEQIILGVLLSFFLALFLILIIYGSVKIHRRKKEGGTYSPRQAEIIETKFKLDQLIAVADLELKEEKINRLLSYRKSLKPISKKS-----FLQHVEDLCANDNAKFQEEFAELPKLLQDLATSDADL--PWNRSKNRFTNIKPYNNSRVKLLSEPGMPGSDYINASFVSG----------YLCPNEFIATQGPL-------PSTVADFWRMIWETGTKTIVMLTQCFEKGRIRCHQYWP-EDNKPVTVFADIIITKLTEDVRPDWTV---RALKVERHGSYMIVHHFNYTSWPEHGVPESSSTLVQFVKAVRSNRGHENTTIVVHCSAGVGRTGVFIALD-HLIQHLRDHEFVDIYGLVAELRSERMCMVQNLAQYMFLHQSTLDLLSAKG 2266          

Query:  750 IRPYTYYGISVNAANVFGWGNLV-SVYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVN-GQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITD--------------------DKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQS-IVDKSQIKIVWSYPIV--HTINYKYDIQVYNGTFSYKDELRG----GSYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSISSSVTGNNIILTWTFGEQSNCLVQFNV-------------------ATTVPENINVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNI---TSTTVTISEWVETDILYTCQVSASTSVG 2408
            + P   Y I V A N  G G    S+Y +T++   G V   +        + + W  P   NG I ++ + V+    GQ V T  +N  D   N ++P    N   +  ++     + T QL+S V+                      D++ P   Y   +      G G +      +     E      V+ +     +++ W+PPK     II                      T  F+ V Q    +  I+E  +I        D +F        + P + Y ++V   +    GP + I++TT    P  V+ L++  VD + +++ W  PI     I +   + +Y+ T      LRG         ++ SL+F T     +   + +   ++ R  +NT   +  A+    S+       LT T  ++++  VQ                      AT V  +++     + +R L   T Y   V+        ++  +G S +    T E VPSSV +    N S T I+ +W PP+  NGKI +Y +  +N  ++ N  +   T TT  +   ++    Y  +V+AST+VG
Sbjct:  101 LTPGATYNIKVAAVNKAGVGPFSQSLYYKTAEAPPGLVSNLTAFAEDHTSVIVTWFLPVRINGLITKFAVKVKHARTGQIVRTKELNAEDIM-NGALPHC--NDAADILSRGTPSPSQTSQLTSAVLPPITLSAVPPASIWSVPISVKIDELRPYTPYVFEVSAFTSDGEGQIASTMVRMPEAAPEDPPQNVVLRNITSKSVSLTWEPPK-----II----------------------TGRFSYVIQLHSSEGLISENSTI--------DQMFIYT----GLTPYTTYYIHVMAKSAGAAGPAAVINITTLAEAPSAVSLLKAEAVDSTSVRLSWRSPIQPNGLITHYRILVLYHDTLVQDITLRGQNLISPLRRNARSLDFTTESVFTLTSHETFS--TLGRDFTNTDTEAPSALPLTPSTPHTPPPWLTVTH-DRTDASVQTQTDAVTEDLTTEHPPVTPVLPATEVSADLSSDQITHVVRRLSPFTEYKFSVS------AKNIIGEGPSTEVTVKTNEQVPSSVQNVSYQNLSSTSIRVSWEPPLNPNGKITHYAVYAQN--LLTNQELRQMTDTTTAVLTGLDKYSSYKVRVAASTAVG 651          

Query: 2046 YEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSV-LSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPV 2423
            Y    L+   PY I VTP +   ++   +    L     T E VPSS  LS    N S T I+ +W PPVE NG+I+ Y +  +  S   N N TS T  +   +     Y   ++A T VG G PV
Sbjct: 1110 YLFTKLRKYFPYIINVTPATSAGSAVNHTTMLHLR----TDEDVPSSPPLSGSNKNLSSTSIQVSWFPPVEANGEIIEYAVNLQGPST-SNKNYTSETHLVLSELTPFTPYNLSIAAVTRVGTGPPV 1231          

Query: 3111 EFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLL----AKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEI----NQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQS----NQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            ++ E ++    DSN    +++ E+K  +V  ++ K       N AKNR+SN+ PY  +RVKL       +DYINA+ +    + S KE        +IA QGP+         T+ +FWRMI E NV  IV LT+  E G+ KC +YWP+      N  +T  SE     +E++   D++I   R+ NV   E    V Q H  AW DHG P T+E L  +    +        +   VVHCSAGVGRTGTFI ID  LS  ++ D  ++IY  + ++R  R  MVQTE QY +++   ++ +
Sbjct:    9 DYEEYFKRNSADSNCGFAEEYEELK--SVGTQQSKAAALAIENKAKNRYSNVLPYDASRVKLSMCGSPFDDYINANHVPG--YNSRKE--------FIAAQGPL-------PVTLNEFWRMIWEKNVYTIVMLTKCNEMGRVKCEKYWPSATSHYNNISVTTTSE-----IELD---DWTIRDFRIKNVKTAETRY-VRQFHFTAWPDHGVPETTEILIDFRHLVREHMDQYSRHSPTVVHCSAGVGRTGTFIAID-HLSFQIERDSMVDIYGIVHDMRMHRALMVQTEDQYVYLHQCAYDLI 282          

Query: 2955 IVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEA----TNTAITHLLPMDS--------KSPAA--------HEFHENYEFMKQDSNGRLLDDFREIKE-LAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVF----NVSMDEKEISVTQLHMLAWKDHGCPT-TSEFLAFYSAYRKARQSNQA-IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHE 3977
            +VG  +AV  IIC+ IAI      KR +          N  IT   P D         ++P           E  E+ E +K + N +L  ++  I        E   +    E N  KNR++N+  Y H+RV L     +  +DYIN++ I     Q          N YIATQGP+ E       T GDFWRM+ E     +V +TR+EE  + KC QYWP+   +  TY      I V +  +++ + F  R F    N S +++E  V Q    AW DHG P   + FLAF    +     +   I+ HCSAGVGRTG FI+ID  L RI K +  ++IY ++  +R  R  MVQTE QY FI+  + E
Sbjct: 1154 VVGPVLAVVFIICIVIAILLYKNSKRKESEPRTKCLLNNADITPHHPTDPVEMRRINFQTPGMMNHPPIPISELAEHTELLKANDNLKLSQEYESIDPGQQFTWEHSNL----EVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINSNYIDGYRKQ----------NAYIATQGPLPE-------TFGDFWRMVWEQRAATVVMMTRLEEKSRIKCDQYWPSRGTE--TYGM----IQVTLLDTIELATFCVRTFSLHKNGSSEKRE--VRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERI-KHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLE 1496          

Query: 3237 NDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ---SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            N  KNR  NI PY+  RV L     L  +DYIN+S I     Q            YIATQGP+ E  E       DFWRM+ ENN  ++V LT++ E G+EKC QYWP E + +  Y+  D      M        ++ R F V+   D +  +V Q     W + G P + E F+ F     K ++    +  I VHCSAGVGRTG FI +   L R ++ +  ++I+  +  LR  R  MVQTE +Y F Y    EYL
Sbjct: 1554 NKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINSSFIDGYRQQ----------KAYIATQGPLAETTE-------DFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ------YILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLER-MRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYL 1789          

Query: 3129 EFMKQ---DSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLL----AKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKE--ISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQA----IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQA 3992
            E+ KQ   DSN     ++ E++ +         +     N  KNR+ N+ PY  +RVKLL      +DYINA+ +    + S KE        +IA QGP+         T+  FWRMI EN V  IV LT+  E GK KC +YWP+E +    +Y     I+V   S  +   +  R F++   E E   +V Q H  AW DHG P T+E L  +    +   +  +     VVHCSAGVGRTGTFI ID  +S+I + D  ++IY  + ++R  R  MVQTE QY ++Y   ++ L+Q+
Sbjct:   10 EYFKQKCADSNHGFAIEYEELRFVGTAQANTAALALE--NKEKNRYLNVLPYDASRVKLLKCENPFDDYINANYV--PGYNSRKE--------FIAAQGPL-------PVTINKFWRMIWENKVYTIVMLTKCNELGKVKCEKYWPSETD----FYHN---ISVTTTSETELDDWTIRDFSIKNVETEETCNVRQFHFTAWPDHGVPETTEVLIEFRHLVREHMNQYSCTSPTVVHCSAGVGRTGTFIAIDHLISQI-ERDSMVDIYGIVHDMRMHRALMVQTEDQYVYLYQCAYD-LIQS 282          

Query: 2955 IVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEA----TNTAITHLLPMDS---------------KSPAAH-----------------EFHENYEFMKQDSNGRLLDDFREIKE-LAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVF----NVSMDEKEISVTQLHMLAWKDHGCPT-TSEFLAFYSAYRKARQSNQA-IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHE 3977
            +VG  +AV  IIC+ IAI      KR +          N  IT   P D                 SP +                  E  E+ E +K + N +L  ++  I        E   +    E N  KNR++N+  Y H+RV L     +  +DYIN++ I     Q          N YIATQGP+ E       T GDFWRM+ E     +V +TR+EE  + KC QYWP+   +  TY      I V +  +++ + F  R F    N S +++E  V Q    AW DHG P   + FLAF    +     +   I+ HCSAGVGRTG FI+ID  L RI K +  ++IY ++  +R  R  MVQTE QY FI+  + E
Sbjct: 1259 VVGPVLAVVFIICIVIAILLYKNSKRKESEPRTKCLLNNADITPHHPTDPVEMRRINFQTPDSGLSSPVSEAGFDYESMMNHPPIPISELAEHTELLKANDNLKLSQEYESIDPGQQFTWEHSNL----EVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINSNYIDGYRKQ----------NAYIATQGPLPE-------TFGDFWRMVWEQRAATVVMMTRLEEKSRIKCDQYWPSRGTE--TYGM----IQVTLLDTIELATFCVRTFSLHKNGSSEKRE--VRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERI-KHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLE 1617          

Query: 3237 NDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ---SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            N  KNR  NI PY+  RV L     L  +DYIN+S I     Q            YIATQGP+ E  E       DFWRM+ ENN  ++V LT++ E G+EKC QYWP E + +  Y+  D      M        ++ R F V+   D +  +V Q     W + G P + E F+ F     K ++    +  I VHCSAGVGRTG FI +   L R ++ +  ++I+  +  LR  R  MVQTE +Y F Y    EYL
Sbjct: 1675 NKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINSSFIDGYRQQ----------KAYIATQGPLAETTE-------DFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ------YILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLER-MRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYL 1910          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNN----------IDMIPDAMSKVNIKVADEY-TQAAITLPY--SHFSNNGGTIQMFTLVISET--RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN--LLGNKSDHNSN----GPLKSGTLYIIGFRAYT---------------SAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAAH--------------EFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKND-----YINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQL----HMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDSNLFRQSYEN 4058
            P  +    C  Q+ T I C+W PP   +     Y + C+           S  V  S+ +E D        +S ++    P   +++ +     DM +          ID  P     + +   D + ++++I   +  S FS+  G ++ FT+++SE    +N    AS+    Y +        K+T +Y+    P +         NP  N Q+ +  +G    LLG K D N N    GPL   T Y I  RA+T               S  F ++        +     I GVS  +FVII + +    +I  ++ K     T    THL     + P+ H              +F E++  ++ DSN  L  ++  +K+   + +     +  E N  KNR+SNI PY   RVKL   +D     YINAS +   +++ E          YIATQGP+   ++       DFW+M+ E NV +IV +T+  E G+ KC  YWP  ++Q   YY +   + V+M S      +  R F +   E +I   +L    H   W DHG P T+    +F+     Y      +   VVHCSAGVGRTGTFI++D  L ++    D ++I+  + +LR  R  MVQTE QY ++Y  + + L +A  +R    N +D+ LF   YEN
Sbjct: 1473 PDKIHHLHCRPQTSTAISCSWTPP---DSDFDGYSVECRRNG--------SDDVEFSKRIEKD-------KSSITISTLVPHKRYVVSIKVHSADMTSQVIEDSAITMIDRPPPPPLLIRVNKKDTFISKSSIHFRFNCSWFSDTNGAVKYFTVIVSEADGNDNQRPEASLPLPSYADYK----TNKSTKIYQTSYFPSRCAE------NPDYNIQSYKIKLGTGMELLGGKCDQNENKYCDGPLSPRTSYRISVRAFTQLFTEEMRTFPEPLYSDTFFSLPITTEAEPL--FGVIEGVSGGMFVIIMIIVLTVLLIYRQKKKRQDPMT----THLSSQIERIPSVHLNVGHIQIGPILTAQFEEHFSKLQTDSNYLLSREYENLKDFG-RDQSSDTALLPE-NRGKNRYSNILPYDSTRVKLANVDDDPCSDYINASYMPGINFRRE----------YIATQGPLPATKD-------DFWKMVWEQNVHIIVMVTQCTERGRAKCDHYWP--MDQDSYYYGD---LIVQMLSESVLPEWTIREFKI-CSEDQIDAPRLVRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRTPGSGPTVVHCSAGVGRTGTFIVLDRMLQQV-DTVDSVDIFGAVRDLRIHRMYMVQTECQYVYLYQCVRDVL-RARKLR----NEQDNPLF-PIYEN 2096          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNN----------IDMIPDAMSKVNIKVADEY-TQAAITLPY--SHFSNNGGTIQMFTLVISET--RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN--LLGNKSDHNSN----GPLKSGTLYIIGFRAYT---------------SAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAAH--------------EFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKND-----YINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQL----HMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDSNLFRQSYEN 4058
            P  +    C  Q+ T I C+W PP   +     Y + C+           S  V  S+ +E D        +S ++    P   +++ +     DM +          ID  P     + +   D + ++++I   +  S FS+  G ++ FT+++SE    +N    AS+    Y +        K+T +Y+    P +         NP  N Q+ +  +G    LLG K D N N    GPL   T Y I  RA+T               S  F ++        +     I GVS  +FVII + +    +I  ++ K     T    THL     + P+ H              +F E++  ++ DSN  L  ++  +K+   + +     +  E N  KNR+SNI PY   RVKL   +D     YINAS +   +++ E          YIATQGP+   ++       DFW+M+ E NV +IV +T+  E G+ KC  YWP  ++Q   YY +   + V+M S      +  R F +   E +I   +L    H   W DHG P T+    +F+     Y      +   VVHCSAGVGRTGTFI++D  L ++    D ++I+  + +LR  R  MVQTE QY ++Y  + + L +A  +R    N +D+ LF   YEN
Sbjct: 1459 PDKIHHLHCRPQTSTAISCSWTPP---DSDFDGYSVECRRNG--------SDDVEFSKRIEKD-------KSSITISTLVPHKRYVVSIKVHSADMTSQVIEDSAITMIDRPPPPPLLIRVNKKDTFISKSSIHFRFNCSWFSDTNGAVKYFTVIVSEADGNDNQRPEASLPLPSYADYK----TNKSTKIYQTSYFPSRCAE------NPDYNIQSYKIKLGTGMELLGGKCDQNENKYCDGPLSPRTSYRISVRAFTQLFTEEMRTFPEPLYSDTFFSLPITTEAEPL--FGVIEGVSGGMFVIIMIIVLTVLLIYRQKKKRQDPMT----THLSSQIERIPSVHLNVGHIQIGPILTAQFEEHFSKLQTDSNYLLSREYENLKDFG-RDQSSDTALLPE-NRGKNRYSNILPYDSTRVKLANVDDDPCSDYINASYMPGINFRRE----------YIATQGPLPATKD-------DFWKMVWEQNVHIIVMVTQCTERGRAKCDHYWP--MDQDSYYYGD---LIVQMLSESVLPEWTIREFKI-CSEDQIDAPRLVRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRTPGSGPTVVHCSAGVGRTGTFIVLDRMLQQV-DTVDSVDIFGAVRDLRIHRMYMVQTECQYVYLYQCVRDVL-RARKLR----NEQDNPLF-PIYEN 2082          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLI----IVPSAVPD--MNNIDMIPDAMSKVNIKVADEY-TQAAITLPY--SHFSNNGGTIQMFTLVISET--RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN--LLGNKSDHNSN----GPLKSGTLYIIGFRAYT---------------SAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAAH--------------EFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKND-----YINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNV-SMDEKEIS--VTQLHMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDSNLFRQSYEN 4058
            P  +    C  Q+ T I C+W PP   +     Y + C+           S  V  S+ +E D      ++ ST V +   V S  +    +    + D  +  ID  P     + +   D + ++++I   +  S FS+  G ++ FT+++SE    +N    AS+    Y +        K+T +Y+    P +         NP  N Q+ +  +G    LLG K D N N    GPL   T Y I  RA+T               S  F ++        +     I GVS  +FVII + I +  ++ Y++ K     T    THL     + P+ H              +F E++  ++ DSN  L  ++  +K+   + +     +  E N  KNR+SNI PY   RVKL   +D     YINAS +   +++ E          YIATQGP+   ++       DFW+M+ E NV +IV +T+  E G+ KC  YWP  ++Q   YY +   + V+M S      +  R F + S D+ +    V   H   W DHG P T+    +F+     Y      +   VVHCSAGVGRTGTFI++D  L ++    D ++I+  + +LR  R  MVQTE QY ++Y  + + L +A  +R    N +D+ LF   YEN
Sbjct: 1362 PDKIHHLHCRPQTSTAISCSWTPP---DSDFDGYSVECRRNG--------SDDVEFSKRIEKD---KSSITISTLVPHKRYVVSIKVHSADMTSQVIEDSAITMIDRPPPPPLLIRVNKKDTFISKSSIHFRFNCSWFSDTNGAVKYFTVIVSEADGNDNQRPEASLPLPSYADYK----TNKSTKIYQTSYFPSRCAE------NPDYNIQSYKIKLGTGMELLGGKCDQNENKYCDGPLSPRTSYRISVRAFTQLFTEEMRTFPEPLYSDTFFSLPITTEAEPL--FGVIEGVSGGMFVIIMI-IVLTVLLIYRQKKKRDPMT----THLSSQIERIPSVHLNVGHIQIGPILTAQFEEHFSKLQTDSNYLLSREYENLKDFG-RDQSSDTALLPE-NRGKNRYSNILPYDSTRVKLANVDDDPCSDYINASYMPGINFRRE----------YIATQGPLPATKD-------DFWKMVWEQNVHIIVMVTQCTERGRAKCDHYWP--MDQDSYYYGD---LIVQMLSESVLPEWTIREFKICSEDQIDAPRLVRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRTPGSGPTVVHCSAGVGRTGTFIVLDRMLQQV-DTVDSVDIFGAVRDLRIHRMYMVQTECQYVYLYQCVRDVL-RARKLR----NEQDNPLF-PIYEN 1984          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNN----------IDMIPDAMSKVNIKVADEY-TQAAITLPY--SHFSNNGGTIQMFTLVISET--RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN--LLGNKSDHNSN----GPLKSGTLYIIGFRAYT---------------SAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAAH--------------EFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKND-----YINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQL----HMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDSNLFRQSYEN 4058
            P  +    C  Q+ T I C+W PP   +     Y + C+           S  V  S+ +E D        +S ++    P   +++ +     DM +          ID  P     + +   D + ++++I   +  S FS+  G ++ FT+++SE    +N    AS+    Y +        K+T +Y+    P +         NP  N Q+ +  +G    LLG K D N N    GPL   T Y I  RA+T               S  F ++        +     I GVS  +FVII + I +  ++ Y++ K     T    THL     + P+ H              +F E++  ++ DSN  L  ++  +K+   + +     +  E N  KNR+SNI PY   RVKL   +D     YINAS +   +++ E          YIATQGP+   ++       DFW+M+ E NV +IV +T+  E G+ KC  YWP  ++Q   YY +   + V+M S      +  R F +   E +I   +L    H   W DHG P T+    +F+     Y      +   VVHCSAGVGRTGTFI++D  L ++    D ++I+  + +LR  R  MVQTE QY ++Y  + + L +A  +R    N +D+ LF   YEN
Sbjct: 1542 PDKIHHLHCRPQTSTAISCSWTPP---DSDFDGYSVECRRNG--------SDDVEFSKRIEKD-------KSSITISTLVPHKRYVVSIKVHSADMTSQVIEDSAITMIDRPPPPPLLIRVNKKDTFISKSSIHFRFNCSWFSDTNGAVKYFTVIVSEADGNDNQRPEASLPLPSYADYK----TNKSTKIYQTSYFPSRCAE------NPDYNIQSYKIKLGTGMELLGGKCDQNENKYCDGPLSPRTSYRISVRAFTQLFTEEMRTFPEPLYSDTFFSLPITTEAEPL--FGVIEGVSGGMFVIIMI-IVLTVLLIYRQKKKRDPMT----THLSSQIERIPSVHLNVGHIQIGPILTAQFEEHFSKLQTDSNYLLSREYENLKDFG-RDQSSDTALLPE-NRGKNRYSNILPYDSTRVKLANVDDDPCSDYINASYMPGINFRRE----------YIATQGPLPATKD-------DFWKMVWEQNVHIIVMVTQCTERGRAKCDHYWP--MDQDSYYYGD---LIVQMLSESVLPEWTIREFKI-CSEDQIDAPRLVRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRTPGSGPTVVHCSAGVGRTGTFIVLDRMLQQV-DTVDSVDIFGAVRDLRIHRMYMVQTECQYVYLYQCVRDVL-RARKLR----NEQDNPLF-PIYEN 2164          

Query: 2049 EMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSV---LSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCK----------NESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNP--KANWQNEEYIVGNN---LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVT-------VGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKH------------------VSEATNTAITHLLPMDSKSPAAHE-FHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYRKAR-QSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            E+  LK  T Y++ VT F+   + +      S   +  T E VP+     +  + +    T ++ T+ PP E NGKI    +  K          N S+I N+N + T V   + ++    Y  ++ A    G G       I      P      M P  +   +  +    T   I +P  +FS++ G I+   +++SE     VGN S     + + AY +               PKP        NP    +  ++EY++G N   +  +  D   NGPLK    Y+  FRA    G  T       V  ++   +  ++  I+ V++ V  +I L  AIY   R ++ +                   + +    A   L       P + + F ++ E +  ++N +  ++F E+ +    L      +    N +KNRF+NIKPY +NRVKL+A      +DYINAS +              C N +IATQGP+       A TVGDFWRM+ E     IV LT+  E G+ +C QYWP E N+ +T + +     V  +  +D++    R   V      + V Q +  +W +HG P +T+  + F    R  R   N   VVHCSAGVGRTG F+ +D  L + +   D ++IY  +  LR  R  MVQ  +QY F++  + + L   G
Sbjct: 1516 EVTGLKPFTNYSVTVTAFTGPSDLAYTEGKLSSVVIVTTLEAVPADPPTNIEIQKIPHDVTKVQMTFIPPSEPNGKIQYQAVVYKEDNPKDSQIRNLSIIKNNNNSITAVI--DGLKGGYTYNIRIYAVNGAGAGPNATQMKITTDITEPP--RPVMQPQPIYNPSGSIRATATTFTIMMPKCYFSDDNGPIKYIQVIVSEVGAQHVGNIS-----WWHEAYHKK--------------PKPYFTSDGFPNPLCSKSRISDEYVIGANESCMALDIKDTFCNGPLKPRKQYLFKFRATNIRGQYTDSVYSEVVKTLDDGLSQTQVEIILSVTLCVLSVILLVGAIYAFARIRQKQKEGGTYSPRDAEIIDTKFKLEQLITVADLELKDERLTRPVSKKGFLQHVEELCTNNNLKFQEEFSELPKFLEDLAVSDADL--PWNRSKNRFTNIKPYNNNRVKLIADAGVPGSDYINASYVSG----------YICPNEFIATQGPL-------AGTVGDFWRMVWETRAKTIVMLTQCYEKGRIRCHQYWP-EDNKPVTVFGDIVITKVAEDVQIDWTT---RDLKVERHGDFMIVRQCNYTSWPEHGVPESTASLMHFVKMIRANRPHENTPTVVHCSAGVGRTGVFVALD-HLVQHINHHDFVDIYGLVAELRSERMCMVQNMAQYIFLHQCVVDLLASKG 2168          

Query: 2028 NVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSV---LSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNES-----VIYNDNITSTT----VTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIP--DAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN---LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVT-------VGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVS--------------------------EATNTAITHLL-------PMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYRKARQSNQA-IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            N  N   E+ +L+  T Y++ +T F    + +     +S + +  T E VP      ++F+ +    T  + ++ PP + NG I  Y      E       I+N +I   T    + + E ++    Y   V A  S G G P     I +    P       IP  DA  K+ +      T   I +P  +++++ G I+   ++++E      GN +     Y N A      +     E   +PP  +   K + N       E Y++G +   ++    +   NGPLK    Y+  FRA    G  T       +  +    +   +  I+ V++ +  II L  AI+   R ++ +                             E  +  +T LL       P+  KS     F ++ E +  ++N +  ++F E+ +    L      +    N AKNRF NIKPY +NRVKL+A      +DYINAS +              C N +IATQGP+         TVGDFWRM+ E     +V LT+  E G+ +C QYWP E N+ +T + +     +  +  +D++I   R   +      ++V Q +   W +HG P  T+  + F    R +R  +   +VVHCSAGVGRTG FI +D  L++ + + D ++IY  +  LR  R  MVQ  +QY F++  I + L   G
Sbjct: 1592 NEENKTTEINDLEVFTRYSVVITAFVGNVSGAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIPDEVTKFQLSFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTDTSVIAMLEGLKGGHTYNISVYAINSAGAG-PKVQMRITMDIKAPARPKTKPIPIHDATGKLLVTS----TTITIRMPICYYNDDHGPIRNVQVLVAEAGAQQDGNVTKWYDAYFNKA------RPYFTNEGFPNPPCIEGKTKFSGN------EEIYVIGADNACMIPGNEEKICNGPLKPKKQYLFKFRATNVMGQFTDSEYSDPIKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRLLSYRKSIKPVSKKS-----FLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADL--PWNRAKNRFPNIKPYNNNRVKLIADVSIPGSDYINASYVSG----------YLCPNEFIATQGPL-------PGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWP-EDNKPVTVFGDILITKLMEDIQIDWTI---RDLKIERHGDCMTVRQCNFTGWPEHGVPENTTPLIHFVKLVRTSRAHDATPMVVHCSAGVGRTGVFIALD-HLTQHIHDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKG 2265          

Query: 2958 VGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNT----------AITHLLPMDSKSPAAHEFHENY--EFMKQDSNGRLLDDFREIKE-----LAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSI---FVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQ----AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEY 3980
            V V+++  ++I   I + +++R+K+ K     +N+               +P+ ++SP+ +  +     + ++++ N R+ DD +  +E      A  ++        E N  KNR+ NI PY H+RV L     +  +DYINAS I       EK       N +IA QGP       K +TV DFWRMI E N   IV +T ++E  + KC+QYWP   +Q    Y        ++   +DY++    +++V +V+  + +  +TQ H  +W D G P T   +      +K +  N     AIVVHCSAGVGRTGTF++ID  L  ++  + ++++Y  +  +R  RCQMVQT+ QY FIY  + E+
Sbjct:  146 VMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQ---EK-------NKFIAAQGP-------KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP---DQGCWTYGNVRVSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFTP--IGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLD-MMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH 492          

Query: 3126 YEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNV--SMDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ--SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            Y  +   SN  L ++F+++  + ++ ++ +       N  KNR   I PY+ NRV +  K      DY+NAS I   + Q +          YIA+QGP+         T+ DFWRMI E   C IV LT +EE G+EKC+QYWP++    +  Y +   I VE+    +   +  R   V  + + K   + Q H   W + G P+  +  +   +A +K +Q   N  I VHCSAG GRTGTF  +   L R+ K +  ++++  + +LR  R  MVQT  QY F Y V+ EY+
Sbjct:  513 YNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLP-ANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFI-DGYRQKDS---------YIASQGPL-------LHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD---GLVSYGD---ITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERV-KAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 783          

Query: 2973 AVFVIICLSIAIYFI---IRYKRNKHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSEFLAFY----SAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDSNLFRQSYENPIFVE*ETKNQFFENNLYI 4115
            AVF  I  ++AI  +   I +++ +  ++    + + + P  SK      F   ++  + DSN    +++ ++K + + L +    +    N  KNR++N+ PY  +RVKL  +    +DYINA+ +   H  S+K+        +IATQGP+         T+ DFWRM+ E NV  IV LT+  E G+ KC +YWP++  Q    Y +   I V M S +    +  R F V    + +   + Q H  +W DHG P T++ L  +      Y K       I+VHCSAGVGRTGTFI ID  + +I  E + +++Y  + +LR  R  MVQTE QY F+   + +      +IR  +D++ D  +++ +    I+   E  + F + N YI
Sbjct:  803 AVFGCIFGALAITAVGGFIFWRKKRTDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPKYTAEI--AENRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYMPGYH--SKKD--------FIATQGPL-------PNTLKDFWRMVWEKNVYAIVMLTKCVEQGRTKCEEYWPSKQAQD---YGD---ITVAMTSEVVLPEWTIRDFVVKNMQNSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENE-NTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLD------IIRAQKDSKVDL-IYQNTTAMTIYENLEPVSMFGKTNGYI 1163          

Query: 2973 AVFVIICLSIAIYFI---IRYKRNKHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSEFLAFY----SAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDSNLFRQSYENPIFVE*ETKNQFFENNLYI 4115
            AVF  I  ++AI  +   I +++ +  ++    + + + P  SK      F   ++  + DSN    +++ ++K + + L +    +    N  KNR++N+ PY  +RVKL  +    +DYINA+ +   H  S+K+        +IATQGP+         T+ DFWRM+ E NV  IV LT+  E G+ KC +YWP++  Q    Y +   I V M S +    +  R F V    + +   + Q H  +W DHG P T++ L  +      Y K       I+VHCSAGVGRTGTFI ID  + +I  E + +++Y  + +LR  R  MVQTE QY F+   + +      +IR  +D++ D  +++ +    I+   E  + F + N YI
Sbjct:  989 AVFGCIFGALAITAVGGFIFWRKKRTDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPKYTAEIAE--NRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYMPGYH--SKKD--------FIATQGPL-------PNTLKDFWRMVWEKNVYAIVMLTKCVEQGRTKCEEYWPSKQAQD---YGD---ITVAMTSEVVLPEWTIRDFVVKNMQNSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENE-NTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLD------IIRAQKDSKVDL-IYQNTTAMTIYENLEPVSMFGKTNGYI 1349          

Query: 2955 IVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAI---THLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKV----------------IMFT------EGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVF----NVSMDEKEISVTQLHMLAWKDHGCPT-TSEFLAFYSAYRKARQSNQA-IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQA 3992
            ++G  +AV  IIC+ IAI     YK  +  SE     +     L P   K P       N++     + G L      I ++A  +ER K                   FT      E N  KNR++N+  Y H+RV L     +  +DYINA+ +     Q          N YIATQGP+ E       T GDFWRM+ E     +V +TR+EE  + KC QYWP    +   +      I V +  +M+ + F  R F    N S +++E  V      AW DHG P   + FLAF    +     +   IVVHCSAGVGRTG FI+ID  L RI K +  +++Y ++  +R  R  MVQTE QY F    IHE L++A
Sbjct:  855 VIGPVLAVVFIICIVIAILL---YKNKRKDSEPRTKCLLNNADLAPHHPKDPVEMR-RINFQ-----TPGMLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQ----------NAYIATQGPLPE-------TFGDFWRMVWEQRSATVVMMTRLEEKSRIKCDQYWPNRGTETYGF------IQVTLLDTMELATFCVRTFSLHKNGSSEKRE--VRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERI-KTEKTVDVYGHVTLMRSQRNYMVQTEDQYGF----IHEALLEA 1197          

Query: 3237 NDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ---SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            N  KNR  NI PY+ +RV L     +  +DYINAS I     Q            YIATQGP+ E  E       DFWR + ENN  ++V LT++ E G+EKC QYWP E + +  Y+  D      M        ++ R F V+   D +  +V Q     W + G P + E F+ F     K ++    +  I VHCSAGVGRTG FI +   L R ++ +  ++I+  +  LR  R  MVQTE +Y F +    EYL
Sbjct: 1254 NKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQ----------KAYIATQGPLAETTE-------DFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ------YILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLER-MRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYL 1489          

Query: 2028 NVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSV---LSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNES-----VIYNDNITSTT----VTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIP--DAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN---LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVT-------VGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKH----VSEATNTAITHLLPMD---------------SKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQA--IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            N  N   E+++L+  T Y++ +T F+   +++     +S + +  T E  P      ++F+ +    T  + T+ PP + NG I  Y      E       I+N +I   T    + + E ++    Y   V A  S G G P     I +    P        P  DA  K+ +      T   I +P  ++S++ G I+   ++++ET     GN +     Y N A      +     E   +PP  +   K + N       E YI+G +   ++    D   NGPLK    Y+  FRA    G  T       V  +    +   +  I+ V++ +  II L  AI+   R ++ +      S      I   L +D               ++  +   F ++ E +  ++N +  ++F E+ +    L      +    N AKNRF NIKPY +NRVKL+A      +DYINAS I              C N +IATQGP+         TVGDFWRM+ E     +V LT+  E G+ +C QYWP E N+ +T + +     +  +  +D++I   R   +      ++V Q +  AW +HG P  S  L  +    +A +++    ++VHCSAGVGRTG FI +D  L++ + + D ++IY  +  LR  R  MVQ  +QY F++  I + L   G
Sbjct: 1633 NEENKTIEIKDLEIFTRYSVVITAFTGNISAAYVEGKSSAEMIVTTLESAPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTNTFVIAMLEGLKGGHTYNISVYAVNSAGAG-PKVPMRITMDIKAPARPKTKPTPIYDATGKLLVTS----TTITIRMPICYYSDDHGPIKNVQVLVTETGAQHDGNVTKWYDAYFNKA------RPYFTNEGFPNPPCTEGKTKFSGN------EEIYIIGADNACMIPGNEDKICNGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPQDAEIIDTKLKLDQLITVADLELKDERLTRPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADL--PWNRAKNRFPNIKPYNNNRVKLIADASVPGSDYINASYISG----------YLCPNEFIATQGPL-------PGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWP-EDNKPVTVFGDIVITKLMEDVQIDWTI---RDLKIERHGDCMTVRQCNFTAWPEHGVPENSAPLIHFVKLVRASRAHDTTPMIVHCSAGVGRTGVFIALD-HLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKG 2297          

Query: 2028 NVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSV---LSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNES-----VIYNDNITSTT----VTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIP--DAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN---LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVT-------VGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVS--------------------------EATNTAITHLL-------PMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYRKAR-QSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            N  N   E+ NL+  T Y++ +T F    + +     +S + +  T E VP      ++F+ +    T  + T+ PP + NG I  Y      E       I+N +I   T    + + E ++    Y   V A  S G G P     I +    P       IP  DA  K+ +      T   I +P  +++++ G I+   ++++ET     GN +     Y N A      +     E   +PP  +   K + N       E Y++G +   ++    +   NGPLK    Y+  FRA    G  T       +  +    +   +  I+ V++ +  II L  AI+  +R ++ +                             E  +  +T LL       P+  KS     F ++ E +  +SN +  ++F E+ +    L      +    N AKNRF NIKPY +NRVKL+A      +DYINAS +              C N +IATQGP+         TVGDFWRM+ E     +V LT+  E G+ +C QYWP E N+ +T + +     +  +  +D++I   R   +      ++V Q +   W +HG P  T+  + F    R +R      +VVHCSAGVGRTG FI +D  L++ +   D ++IY  +  LR  R  MVQ  +QY F++  I + L   G
Sbjct: 1594 NEENKTTEINNLEVFTRYSVVITAFVGNVSRAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIRVYQALVYREDDPTAVQIHNFSIIQKTDTSIIAMLEGLKGGHTYNISVYAINSAGAG-PKVQMRITMDIKAPARPKSKPIPIRDATGKLLVTS----TTITIRMPICYYNDDHGPIRNVQVLVAETGAQQDGNVTKWYDAYFNKA------RPYFTNEGFPNPPCIEGKTKFSGN------EEIYVIGADNACMIPGNEEKICNGPLKPKKQYLFKFRATNVMGQFTDSEYSDPIKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFVRIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRLLSYRKSIKPISKKS-----FLQHVEELCTNSNLKFQEEFSELPKFLQDLSSTDADL--PWNRAKNRFPNIKPYNNNRVKLIADVSLPGSDYINASYVSG----------YLCPNEFIATQGPL-------PGTVGDFWRMVWETRTKTLVMLTQCFEKGRIRCHQYWP-EDNKPVTVFGDIVITKLMEDIQIDWTI---RDLKIERHGDCMTVRQCNFTGWPEHGVPENTTPLIHFVKLVRTSRAHDTTPMVVHCSAGVGRTGVFIALD-HLTQHINNHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKG 2267          

Query: 1923 SSSVTGNNIILTWTF--GEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWA-PPVEKNGKILNYWLTCKN----ESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISET-RNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAG-FVTVGF-IERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRN-----KHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTE--GNDAKNRFSNIKPYKHNRVKLLA-----KNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLA-FYSAYRKARQSNQ-AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVI 3971
            ++++T   I L W    GE ++  + +  A  +      T N+  + +L+    YT  V        SSV    + L     T E VP  V  F   +   + I   W+ P  E NG I  + +   N          D  +     + + ++    Y  ++ A T++G+G P   +   +P   P      ++P  + + +  +        I    ++FS+  G ++M+T++++E    N  G    + L  Q+             Y + L    P +A+     P  N   E++ +G     N      NGPLKSGT Y +  RA+T A  F    +    +T  +  S IV ++V + +I+ L + + F  R + N     K      N ++   +   ++      F E+Y  M  DS+ R  ++F E+K +     R +   F +   N  KNRF+NI PY H+R KL        +DYINA+ +   +   E          +I TQGP+   R+       DFWRM  E+N   IV LTR  E G+EKC QYWP   N  +  +  D  I V++ +   Y+ +V   F +    ++  +   H   W D G P   + L  F  A+R    + Q  IVVHCSAGVGR+GTFI +D  L +I    D ++I+  +  +RK R  MVQTE QY  I+  +
Sbjct:  872 ATNITDTEISLRWDLPKGEYNDFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVV-VRSGTESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFG-PEREYRQTMPILAPPRPATQVVPTEVYRSSSTIQ-------IRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLDVQS-------------YSVWL----PYQAID-PYYPFENRSVEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFTGADKFTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVG----RDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPRE----------FIVTQGPLHSTRD-------DFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP---NDTVPVFYGD--IKVQILNDSHYADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQQI-NTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCL 1524          

Query: 2028 NVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSV---LSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNES-----VIYNDNITSTT----VTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIP--DAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN---LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVT-------VGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVS--------------------------EATNTAITHLL-------PMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYRKARQSNQA-IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            N  N   E+ +L+  T Y++ +T F    + +     +S + +  T E VP      ++F+ +    T  + ++ PP + NG I  Y      E       I+N +I   T    + + E ++    Y   V A  S G G P     I +    P       IP  DA  K+ +      T   I +P  +++++ G I+   ++++E      GN +     Y N A      +     E   +PP  +   K + N       E Y++G +   ++    +   NGPLK    Y+  FRA    G  T       +  +    +   +  I+ V++ +  II L  AI+   R ++ +                             E  +  +T LL       P+  KS     F ++ E +  ++N +  ++F E+ +    L      +    N AKNRF NIKPY +NRVKL+A      +DYINAS +              C N +IATQGP+         TVGDFWRM+ E     +V LT+  E G+ +C QYWP E N+ +T + +     +  +  +D++I   R   +      ++V Q +   W +HG P  T+  + F    R +R  +   +VVHCSAGVGRTG FI +D  L++ + + D ++IY  +  LR  R  MVQ  +QY F++  I + L   G
Sbjct: 1592 NEENKTTEINDLEVFTRYSVVITAFVGNVSGAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIPDEVTKFQLSFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTDTSVIAMLEGLKGGHTYNISVYAINSAGAG-PKVQMRITMDIKAPARPKTKPIPIHDATGKLLVTS----TTITIRMPICYYNDDHGPIRNVQVLVAEAGAQQDGNVTKWYDAYFNKA------RPYFTNEGFPNPPCIEGKTKFSGN------EEIYVIGADNACMIPGNEEKICNGPLKPKKQYLFKFRATNVMGQFTDSEYSDPIKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRLLSYRKSIKPVSKKS-----FLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADL--PWNRAKNRFPNIKPYNNNRVKLIADVSIPGSDYINASYVSG----------YLCPNEFIATQGPL-------PGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWP-EDNKPVTVFGDILITKLMEDIQIDWTI---RDLKIERHGDCMTVRQCNFTGWPEHGVPENTTPLIHFVKLVRTSRAHDATPMVVHCSAGVGRTGVFIALD-HLTQHIHDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKG 2265          

Query: 2958 VGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNT----------AITHLLPMDSKSPAAHEFHENY--EFMKQDSNGRLLDDFREIKE-----LAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSI---FVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQ----AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLV 3986
            V V+++  ++I   I + +++R+K+ K     +N+               +P+ ++SP+ +  +     + ++++ N R+ DD +  +E      A  ++        E N  KNR+ NI PY H+RV L     +  +DYINAS I       EK       N +IA QGP       K +TV DFWRMI E N   IV +T ++E  + KC+QYWP   +Q    Y        ++   +DY++    +++V +++  + +  +TQ H  +W D G P T   +      +K +  N     AIVVHCSAGVGRTGTF++ID  L  ++  + ++++Y  +  +R  RCQMVQT+ QY FIY  + E+ +
Sbjct:  155 VMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQ---EK-------NKFIAAQGP-------KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP---DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTP--IGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLD-MMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL 503          

Query: 3126 YEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNV--SMDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ--SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            Y  +   SN  L ++F+++  + ++ ++ +       N  KNR   I PY+ NRV +  K      DY+NAS I   + Q +          YIA+QGP+         T+ DFWRMI E   C IV LT +EE G+EKC+QYWP++    +  Y +   I VE+    +   +  R   V  + + K   + Q H   W + G P+  +  ++  +A +K +Q   N  I VHCSAG GRTGTF  +   L R+ K +  ++++  + +LR  R  MVQT  QY F Y V+ EY+
Sbjct:  522 YNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNL-PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFI-DGYRQKDS---------YIASQGPL-------LHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD---GLVSYGD---ITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERV-KAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 792          

Query:  516 NISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVS-VYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQ-FNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTG-NYTSISPNVSEPISNLSV-IFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISN-ISVTTPQYQPDPVTNLQ-SIVDKSQIKIVWSYPIVHT---INYKYDIQVYNGTFSYKDELRGG--SYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSI--SSSVTGNNIILTWTFGEQSNCLVQFNVATTVPENINVT---------NNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVE--KNGKILNYWL------TCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYG----APVFSFLIIVPSA-VPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISET------RNNIVGNASITSLQ-YQNVAYGECITKNTCVYEIRLSPPKP-KRALKRNTNPKANWQNEEYIVGNNLLGN-KSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRN-------KHVSEATNTAITH--------------------LLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVK---LERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLL-----AKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYR---KARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNRED 4028
            N+ WE PQ PNG++  Y+++ ++     +   T +        N+S                 NS++  + +I     + P + Y   V A N  G G + + +   T++ T G V   +++      ++I W  P   NG+++ Y + V   +  CV  ++ +CTDC P IS          +CT+    Q F++  ++   V     ++P   Y   +      G G        ++    SEP + ++V I       L I W+ P N    I  Y             L+  +N T  F+N +                  +F +  D+ S             + + VR  T+ G G  S  ++V T + +P    ++    +  + I++ W  P++     I Y   +   +     K+E +    + +F +  L+ C +YT  V         + +   +N+T ++      I  + ++T  +I++ W       C + + V  T  ++  +          + + E+ NLK    Y IKV        +       ++    +     P + ++  C +  Y  +  TW  P    KNG I  Y +        KN+ +      +ST  ++S     +  Y  +V+A T VG G    AP +  L   P   V   N    +  A       V D   Q ++ +P S F +  G ++  +++++E        +++  +    +L+ +  V   E IT     Y I+   P P   A +R       +   E I+G+    N  +    NGPL SG  Y I  R YT+ G+     +++ T  +    I G   AV +++ ++  + FII  +R        +  ++   +   H                         S+  +  +F E+ E   +DS+    D+++ +KELA     LE +K       N  KNR++NI P+ H+RVKLL       +DYINA+ +    ++S++E        +IA QGP+   ++       DFWRMI E NV ++V +T+  E G+ KC QYWP +   +  YY +   + V+M S    S +  R+ +V + E    + Q H   W DHGCP +T+  + F    R     R +   I+VHCSAGVGRTGTFI +D  L  I +E + ++I+  +L +R+ RC MVQTE QY +I+  I + + Q   + +   N ED
Sbjct:  710 NLKWEEPQHPNGKVTDYFIEYWQADHKTKEYDTYY--------NIST----------------NSADTSYSVI----NLIPGSTYKFQVKAVNSKGPGEVSNNITVTTNESTPGEVSNLTVSQNTSMSMNIGWEEPIEPNGEVITYEMHVLLEDKSCVQQVTFSCTDC-PAISKISEKSEEAPSCTSTDTTQSFSIHGRVDYTV---RNLVPYTNYTFRVYPFTSVGRGKSKDMREQTLEDTPSEPRNVMAVNITQNEKTGLNITWEAPDNPRGIITGYQ------------LRVTVNDTSNFHNTTD-----------------EFKALPDLLSY----------QNHTIEVRAYTVAGPGNWSKPLTVLTGEARPSAPQHIAFGDISPTSIEVQWQDPVMKRGILIGYLIIVTKASNGEVVKNETQDANEAKSFDATGLDPCQHYTFKVAARTSKGFGNYSSEQTNSTAVNIPGTPVIVKAEAITSTSILVMWIPPPNETCPIDYVVEVTDNDSKEIVKEIPIKGYNSTEKEITNLKKFWSYDIKV---KANTTAGPSMPSTNVKNTTLEDTPGPPARVNASC-DVCYNSMTVTWEAPTRENKNGIITGYVIYYTDGEISKNKKIDIGSQKSSTITSLS----AEKSYQVKVAARTRVGEGEKETAPTYVNLTSGPPIFVAPANTFAKVSTA------SVEDARKQISLQVPSSPFGSENGIVRNISVIVAEDSEAGKPESDVRKDNKFPTLKTWGQVKDLEKITP----YAIKEVEPNPWGTAGQRQRRAATPY---EIIIGSQDCSNVATSKYCNGPLPSGRTYCIRIRGYTTNGYTDTPCVKQGTEPDTTGAIAGGVTAVLIVLIIAFVVLFIIAKRRGLIGGKSQRETTQRNPSTAGHDNEGFDGEELKSRSSESDEEEEAWKSRPVSTSQFKEHVEKYHRDSDLLFSDEYKTVKELAPSYEWLEAEK-----PSNRCKNRYTNILPFDHSRVKLLPIDDDEGSDYINANYMPG--YRSKRE--------FIAAQGPLPATKD-------DFWRMIWEQNVTLVVMVTQCVERGRIKCEQYWPKDTEAE--YYGD---LVVQMRSESTLSDYTIRILDVQLGEFSRVLKQFHFTKWPDHGCPESTTLLINFVQNVRMHISHRPNRGPILVHCSAGVGRTGTFIAVDRLLQHI-REHNEVDIFGLVLEMRENRCNMVQTEDQYIYIHECIKDAIAQG--MHLNNGNLED 1841          

Query:  477 NLSTSSAFPLHPLNIS------------WERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVS-VYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQ-FNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTG-NYTSISPNVSEPISNLSV-IFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISN-ISVTTPQYQPDPVTNLQ-SIVDKSQIKIVWSYPIVHT---INYKYDIQVYNGTFSYKDELRGG--SYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSI--SSSVTGNNIILTWTFGEQSNCLVQFNVATTVPENINVT---------NNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVE--KNGKILNYWL------TCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYG----APVFSFLIIVPSA-VPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISET------RNNIVGNASITSLQ-YQNVAYGECITKNTCVYEIRLSPPKP-KRALKRNTNPKANWQNEEYIVGNNLLGN-KSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRN----KHVSEATNTAITHLLPMDSKSPAAHEF---------HENYEFMKQDSNGRLLDDFR---------------------EIKELAVKLERQKVIMFTE--------------------GNDAKNRFSNIKPYKHNRVKLL-----AKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYR---KARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNRED 4028
            N+ST    P  P+N++            WE PQ PNG++  Y+++ ++     +   T +        N+S                 NS++  + +I     + P + Y   V A N  G G + + +   T++ T G V   +++      ++I W  P   NG+++ Y + V   +  CV  ++ +CTDC P IS          +CT+    Q F++  ++   V     ++P   Y   +      G G        ++    SEP + ++V I       L I W+ P N    I  Y             L+  +N T  F+N +                  +F +  D+ S             + + VR  T+ G G  S  ++V T + +P    ++    +  + I++ W  P++     I Y   +   +     K+E +    + +F +  L+ C +YT  V         + +   +N+T ++      I  + ++T  +I++ W       C + + V  T  ++  +          + + E+ NLK    Y IKV        +       ++    +     P + ++  C +  Y  +  TW  P    KNG I  Y +        KN+ +      +ST  ++S     +  Y  +V+A T VG G    AP +  L   P   V   N    +  A       V D   Q ++ +P S F +  G ++  +++++E        +++  +    +L+ +  V   E IT     Y I+   P P   A +R       +   E I+G+    N  +    NGPL SG  Y I  R YT+ G+     +++ T  +    I G   AV +++ ++  + FII  +R       +        T L+ M   +P++              N      D+ G   ++ +                     + KE   K  R   ++F++                     N  KNR++NI P+ H+RVKLL       +DYINA+ +    ++S++E        +IA QGP+   ++       DFWRMI E NV ++V +T+  E G+ KC QYWP +   +  YY +   + V+M S    S +  R+ +V + E    + Q H   W DHGCP +T+  + F    R     R +   I+VHCSAGVGRTGTFI +D  L  I +E + ++I+  +L +R+ RC MVQTE QY +I+  I + + Q   + +   N ED
Sbjct:  685 NVSTEEIPPSAPINLTSDEKTTNSTNLKWEEPQHPNGKVTDYFIEYWQADHKTKEYDTYY--------NIST----------------NSADTSYSVI----NLIPGSTYKFQVKAVNSKGPGEVSNNITVTTNESTPGEVSNLTVSQNTSMSMNIGWEEPIEPNGEVITYEMHVLLEDKSCVQQVTFSCTDC-PAISKISEKSEEAPSCTSTDTTQSFSIHGRVDYTV---RNLVPYTNYTFRVYPFTSVGRGKSKDMREQTLEDTPSEPRNVMAVNITQNEKTGLNITWEAPDNPRGIITGYQ------------LRVTVNDTSNFHNTTD-----------------EFKALPDLLSY----------QNHTIEVRAYTVAGPGNWSKPLTVLTGEARPSAPQHIAFGDISPTSIEVQWQDPVMKRGILIGYLIIVTKASNGEVVKNETQDANEAKSFDATGLDPCQHYTFKVAARTSKGFGNYSSEQTNSTAVNIPGTPVIVKAEAITSTSILVMWIPPPNETCPIDYVVEVTDNDSKEIVKEIPIKGYNSTEKEITNLKKFWSYDIKV---KANTTAGPSMPSTNVKNTTLEDTPGPPARVNASC-DVCYNSMTVTWEAPTRENKNGIITGYVIYYTDGEISKNKKIDIGSQKSSTITSLS----AEKSYQVKVAARTRVGEGEKETAPTYVNLTSGPPIFVAPANTFAKVSTA------SVEDARKQISLQVPSSPFGSENGIVRNISVIVAEDSEAGKPESDVRKDNKFPTLKTWGQVKDLEKITP----YAIKEVEPNPWGTAGQRQRRAATPY---EIIIGSQDCSNVATSKYCNGPLPSGRTYCIRIRGYTTNGYTDTPCVKQGTEPDTTGAIAGGVTAVLIVLIIAFVVLFIIAKRRGVDRFTRIDSDDKEGPTVLM-MQDLNPSSRLIGGKSQRETTQRNPSTAGHDNEGFDGEELKSRSSESDEEEEAWKSRPVSTSQFKEHVEKYHRDSDLLFSDEYKTVKELAPSYEWLEAEKPSNRCKNRYTNILPFDHSRVKLLPIDDDEGSDYINANYMPG--YRSKRE--------FIAAQGPLPATKD-------DFWRMIWEQNVTLVVMVTQCVERGRIKCEQYWPKDTEAE--YYGD---LVVQMRSESTLSDYTIRILDVQLGEFSRVLKQFHFTKWPDHGCPESTTLLINFVQNVRMHISHRPNRGPILVHCSAGVGRTGTFIAVDRLLQHI-REHNEVDIFGLVLEMRENRCNMVQTEDQYIYIHECIKDAIAQG--MHLNNGNLED 1869          

Query:  477 NLSTSSAFPLHPLNIS------------WERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVS-VYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQ-FNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTG-NYTSISPNVSEPISNLSV-IFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISN-ISVTTPQYQPDPVTNLQ-SIVDKSQIKIVWSYPIVHT---INYKYDIQVYNGTFSYKDELRGG--SYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSI--SSSVTGNNIILTWTFGEQSNCLVQFNVATTVPENINVT---------NNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVE--KNGKILNYWL------TCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYG----APVFSFLIIVPSA-VPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISET------RNNIVGNASITSLQ-YQNVAYGECITKNTCVYEIRLSPPKP-KRALKRNTNPKANWQNEEYIVGNNLLGN-KSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRN----KHVSEATNTAITHLLPMDSKSPAAHEF---------HENYEFMKQDSNGRLLDDFR---------------------EIKELAVKLERQKVIMFTE--------------------GNDAKNRFSNIKPYKHNRVKLL-----AKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYRKARQSN--QAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNRED 4028
            N+ST    P  P+N++            WE PQ PNG++  Y+++ ++     +   T +        N+S                 NS++  + +I     + P + Y   V A N  G G + + +   T++ T G V   +++      ++I W  P   NG+++ Y + V   +  CV  ++ +CTDC P IS          +CT+    Q F++  ++   V     ++P   Y   +      G G        ++    SEP + ++V I       L I W+ P N    I  Y             L+  +N T  F+N +                  +F +  D+ S             + + VR  T+ G G  S  ++V T + +P    ++    +  + I++ W  P++     I Y   +   +     K+E +    + +F +  L+ C +YT  V         + +   +N+T ++      I  + ++T  +I++ W       C + + V  T  ++  +          + + E+ NLK    Y IKV        +       ++    +     P + ++  C +  Y  +  TW  P    KNG I  Y +        KN+ +      +ST  ++S     +  Y  +V+A T VG G    AP +  L   P   V   N    +  A       V D   Q ++ +P S F +  G ++  +++++E        +++  +    +L+ +  V   E IT     Y I+   P P   A +R       +   E I+G+    N  +    NGPL SG  Y I  R YT+ G+     +++ T  +    I G   AV +++ ++  + FII  +R       +        T L+ M   +P++              N      D+ G   ++ +                     + KE   K  R   ++F++                     N  KNR++NI P+ H+RVKLL       +DYINA+ +    ++S++E        +IA QGP+   ++       DFWRMI E NV ++V +T+  E G+ KC QYWP +   +  YY +   + V+M S    S +  R+ +V +     +V   +   W D GCP TT   L F    R   + +    I VHCSAGVGRTGTFI +D  L  I +E + ++I+  +L +R+ RC MVQTE QY +I+  I + + Q   + +   N ED
Sbjct:  685 NVSTEEIPPSAPINLTSDEKTTNSTNLKWEEPQHPNGKVTDYFIEYWQADHKTKEYDTYY--------NIST----------------NSADTSYSVI----NLIPGSTYKFQVKAVNSKGPGEVSNNITVTTNESTPGEVSNLTVSQNTSMSMNIGWEEPIEPNGEVITYEMHVLLEDKSCVQQVTFSCTDC-PAISKISEKSEEAPSCTSTDTTQSFSIHGRVDYTV---RNLVPYTNYTFRVYPFTSVGRGKSKDMREQTLEDTPSEPRNVMAVNITQNEKTGLNITWEAPDNPRGIITGYQ------------LRVTVNDTSNFHNTTD-----------------EFKALPDLLSY----------QNHTIEVRAYTVAGPGNWSKPLTVLTGEARPSAPQHIAFGDISPTSIEVQWQDPVMKRGILIGYLIIVTKASNGEVVKNETQDANEAKSFDATGLDPCQHYTFKVAARTSKGFGNYSSEQTNSTAVNIPGTPVIVKAEAITSTSILVMWIPPPNETCPIDYVVEVTDNDSKEIVKEIPIKGYNSTEKEITNLKKFWSYDIKV---KANTTAGPSMPSTNVKNTTLEDTPGPPARVNASC-DVCYNSMTVTWEAPTRENKNGIITGYVIYYTDGEISKNKKIDIGSQKSSTITSLS----AEKSYQVKVAARTRVGEGEKETAPTYVNLTSGPPIFVAPANTFAKVSTA------SVEDARKQISLQVPSSPFGSENGIVRNISVIVAEDSEAGKPESDVRKDNKFPTLKTWGQVKDLEKITP----YAIKEVEPNPWGTAGQRQRRAATPY---EIIIGSQDCSNVATSKYCNGPLPSGRTYCIRIRGYTTNGYTDTPCVKQGTEPDTTGAIAGGVTAVLIVLIIAFVVLFIIAKRRGVDRFTRIDSDDKEGPTVLM-MQDLNPSSRLIGGKSQRETTQRNPSTAGHDNEGFDGEELKSRSSESDEEEEAWKSRPVSTSQFKEHVEKYHRDSDLLFSDEYKTVKELAPSYEWLEAEKPSNRCKNRYTNILPFDHSRVKLLPIDDDEGSDYINANYMPG--YRSKRE--------FIAAQGPLPATKD-------DFWRMIWEQNVTLVVMVTQCVERGRIKCEQYWPKDTEAE--YYGD---LVVQMRSESTLSDYTIRILDVQLGNNTRTVRHFNFTVWPDFGCPDTTRSLLEFVKVVRTHIKPDIQGPICVHCSAGVGRTGTFIAVDRLLQHI-REHNEVDIFGLVLEMRENRCNMVQTEDQYIYIHECIKDAIAQG--MHLNNGNLED 1868          

Query: 2238 WAPPVEKNGKILNYWLTCKNESVIYNDNITST-TVTISEWVET----------DILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETR--NNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL---LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTT-SEFLAFYSAYRKARQS-NQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIY 3962
            W PP  +NGKI  Y +   ++   +N  I+ T  V  S+++E           D  Y   + A+T    G   F   +I+ + +P +   D   + +  ++ K       A +T+PYS F +  G I    ++++E     ++         +    ++ E  +  +CV + +      +      T  +   +   + VGN   G+   +  NGPLK G  Y+I  R +T  GF    +I  KT   K      +S+++   +C+   I F I YK+ + + E +          D K    ++F + +  M  D N R+ +++  I+  A  L+  K  + ++ N+  NR++NI P+ +NRV L     +NDYINAS I   H+  E          YIA QGP       K  T  DFWRMIL++ V  IV LT   E  + KC +Y+P ++N +IT+ +    IN+   S  ++  F++R+  V  D++  +V   +  +W DHG P++ S  + F   +R  RQ  + +IVVHCSAGVGRTGTFI +D  + R LK++ +I I+  +  LR  R +MVQT  QY F+Y
Sbjct:  592 WTPPCRRNGKITKYIINAVHQ---FNPQISWTYEVDASQYIEEYSFNVENFQPDSQYNVSIQANTEEFIGRETFQ-TVILEAGLPLLTEWDS-NEVIYSISTK------DARLTIPYSIFHSEVGRITKILILVAEMSCDGDLTPEKGFVGKEPYLKSWREA-SSESCVPQYQTGTITDESIQTLTT--EEGLEVFIFTVGNENCGDSPSY-CNGPLKPGASYLITMRVFTRRGFSDTDYILIKTE--KEVPFYTISISILSTMCVVFMIGFYITYKKTRTLREQSMD-----FSNDKKDIPINDFGKYFSEMSADDNARMKEEYAAIQAYAESLD--KTFIASKANEKLNRYTNISPFDYNRVVLNDDEFENDYINASHINGYHYPRE----------YIAAQGP-------KPNTAIDFWRMILQHKVESIVMLTSFVEEDRIKCHEYFP-KLNGQITFSN----INIICKSEENHQNFIKRIMEVEKDDEIHTVKHYYFTSWSDHGIPSSPSALIEFCKLFRSERQKLSGSIVVHCSAGVGRTGTFIALDIIMQR-LKQEKKINIFELINQLRLQRMKMVQTLDQYVFLY 1137          

Query: 2163 TGEGVPSSVLSFKC-VNQSYTGIKCTWAPPVEKNGKILNYWLTC-------KNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSV--GYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGN-------------KSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVA----VFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLL--------------------PMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLA-----KNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYRK--ARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            T   VP +  + K   NQ  T  + +W+PP   NG I+ Y +         KN  +  +D      +++   +  +  YT  V A        G P      I+P+ +P + N        SK+ +K +  + +  I      FS+  G +  + +++  T  + +GNA+          + + I   +  Y+   +PP+         NP    QN+      N  G+              ++   NGPL+  T Y +  RA+T  G+     +  +TA    S+ +G   A    +F++I L + +  + R  + + + +   +   H                      P+D      H F E+   M  DS+ R   +F  +K  + +       M  E N  KNR+ NI PY H+RVKLL       +D++NA+ I       E          YIA+QGP+         TV DFWRMI E +V VIV LT+  E GK KC QYWP     K  YY +   + V   S    S +V RVF+V +  +E+ V Q+H   W D GCP +  + + F  A R    R     I+VHCSAGVGRTGTFI +D  LS+ L   D I++Y  +L+LR+ R  MVQTE QY +I+  +++ +
Sbjct:  937 TPADVPDAPQNVKAECNQQPTEAEVSWSPPKYPNGLIVKYRIEYGLENSYKKNAYLTVSDPCKEQKISLQN-LRPERHYTITVRARVQGVDSDGHPATFKPCILPAGIPPLGN-------TSKILVKESGPH-RLMIEWSRDAFSDYMGALVRYAVLVGLT--DALGNATSGKTSENLPNWSKFIEGESNYYQA--TPPE--------WNPFDKSQNDSLECKPNTDGSILKCTIGLESYCPNNETYCNGPLRPATQYEMKLRAFTRGGYAESQPLLARTAPAPSSSYLGALAAGLTLLFIVIFLLMGLMVLQRKGKLEPLRQVIRSRFGHTAPSAPPIPEPPQQIEIYQTRGPLD-----VHNFSEHVRIMMSDSHLRFSQEFEALKRSSPQFPCATAEM--EENRGKNRWMNIYPYDHSRVKLLPLGDEPGSDFVNANYIPGNSSLRE----------YIASQGPL-------PNTVDDFWRMIWEQSVTVIVMLTQCVERGKNKCEQYWPAPGEMK--YYGD---LQVRTLSESMLSSYVIRVFHVQLGPRELRVKQMHFTRWPDFGCPESPDDLINFVRAVRDHLPRVRPGPILVHCSAGVGRTGTFIAVD-RLSQQLMRSDVIDVYGTVLDLRQYRTNMVQTEDQYIYIHLCVNQLI 1547          

Query: 2949 STIVGVSVAV--FVIICLSIAIYFIIRYKRNKHVSEATN--------TAITHL--LPMDSKSPAAHEFHENY--EFMKQDSNGRLLDD---FRE-IKELAV-KLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSM---DYSI---FVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQ----AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEY 3980
            + I+ V VA+   ++I   I + +++R+K+ K     +N        T  T L  +P+ ++SP+ +  +     + ++++ N R+ DD   FRE    L V  ++        E N  KNR+ NI PY H+RV L     +  +D+INAS I   +   EK       N +IA QGP       K +TV DFWRMI E N   IV +T ++E  + KC+QYWP   +Q    Y     I V +   M   DY+I    +++V +VS  + +  VTQ H  +W D G P T   +      +K +  N      IVVHCSAGVGRTGTFI+ID  L  ++  + +++++  +  +R  RCQMVQT+ QY FI+  + E+
Sbjct:  192 TAIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLTNGRTEDTELQSVPLLARSPSTNRKYPPLPVDKLEEEMNRRMADDNKLFREEFNALPVCPIQASCDAASKEENKEKNRYVNILPYDHSRVHLSSLEGVPDSDFINASYI---NGYQEK-------NKFIAAQGP-------KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP---DQGCWTYGN---IRVSVEDVMVLVDYTIRKFCIQQVGDVSGKKPQRLVTQFHFTSWPDFGVPFTP--IGMLKFLKKVKTCNPQYAGPIVVHCSAGVGRTGTFIVIDAMLD-MMGAERKVDVFGFVTRIRAQRCQMVQTDMQYVFIFQALLEH 543          

Query: 3153 GRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ--SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            G L  +F+++  + ++ ++ +       N  KNR   I PY+ NRV +  K      DY+NAS I   + Q +          Y+A+QGP+         T+ DFWRMI E   C IV LT +EE G+EKC+QYW ++          D  I ++     +     + +   + + K  +V Q H   W + G PT  +  +   +A +K +Q   N  I VHCSAG GRTGTF  +   L R+ K +  ++++  + +LR  R  MVQT  QY F Y V+ EY+
Sbjct:  573 GGLEAEFKKLTSIKIQNDKMRTGNLP-ANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFI-DGYRQKDS---------YMASQGPL-------QHTIEDFWRMIWEWRSCSIVMLTELEERGQEKCAQYWSSD----GVMVCGDLSIELKREDECESYTVRDLLVTNNRENKARAVRQFHFHGWPEVGIPTDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERV-KAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 834          

Query: 2838 NGPLKSGTLYIIGFRAYT------SAGFVTVGF------IERKTAVNKISTIV-GVSVAVFVIICLSIAIYFIIRYKRNKHV--------------SEATNTAITHLLP----MDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEIS----VTQLHMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDN 4019
            +GPL S T Y +  RA+T      +  F    F      +  +T    +  IV G+S  +F +I + IAI  +I YK+  H                E +NT +   +     + S   AAH F  +   ++ DSN    ++F ++K++  + +        E N  KNR++NI PY   RVKLL       +D+INAS I    +  E          YIATQGP+   ++       DFWRM+ E+NV  IV +T+  E G+ KC QYWPT+  ++  YY E   + V M S    S ++ R F +S  E ++S    V   +   W DHG P T+    +F+     Y     ++   VVHCSAGVGRTGTFI++D  L + L     ++IY ++ +LR  R  MVQTESQY F++  + + L +A  +R  ++N
Sbjct: 1478 DGPLASRTPYRLSVRAFTQLYDGENKQFSHPLFSDTYLSLPLRTKAEPMGGIVEGISTGLF-LISMVIAITTLIIYKQRVHKVAVQESPVVRMSMWKEVSNTGMYMGIRSNRCISSPIKAAH-FESHLSKLQADSNYLFSEEFEDLKDVG-RNQTLDAARLPE-NRCKNRYNNILPYDATRVKLLCLEDDPCSDFINASFIPGNSFGRE----------YIATQGPLPGTKD-------DFWRMVWEHNVYNIVMVTQCVEKGRVKCDQYWPTD--REPLYYGE---LVVHMLSESVLSEWIIREFKISR-EGQLSYPRIVRHFNYTVWPDHGVPETTQSLIQFVRTVRDYIDRAPTSGPTVVHCSAGVGRTGTFIVLDRALQQ-LDSRGTVDIYGSVRDLRLHRIHMVQTESQYMFLHQCVRDVL-RARKLRCEQEN 1886          

Query: 2838 NGPLKSGTLYIIGFRAYT------SAGFVTVGF------IERKTAVNKISTIV-GVSVAVFVIICLSIAIYFIIRYKRNKHV--------------SEATNTAITHLLP----MDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEIS----VTQLHMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDN 4019
            +GPL S T Y +  RA+T      +  F    F      +  +T    +  IV G+S  +F +I + IAI  +I YK+  H                E +NT +   +     + S   AAH F  +   ++ DSN    ++F ++K++  + +        E N  KNR++NI PY   RVKLL       +D+INAS I    +  E          YIATQGP+   ++       DFWRM+ E+NV  IV +T+  E G+ KC QYWPT+  ++  YY E   + V M S    S ++ R F +S  E ++S    V   +   W DHG P T+    +F+     Y     ++   VVHCSAGVGRTGTFI++D  L + L     ++IY ++ +LR  R  MVQTESQY F++  + + L +A  +R  ++N
Sbjct: 1478 DGPLASRTPYRLSVRAFTQLYDGENKQFSHPLFSDTYLSLPLRTKAEPMGGIVEGISTGLF-LISMVIAITTLIIYKQRVHKVAVQESPVVRMSMWKEVSNTGMYMGIRSNRCISSPIKAAH-FESHLSKLQADSNYLFSEEFEDLKDVG-RNQTLDAARLPE-NRCKNRYNNILPYDATRVKLLCLEDDPCSDFINASFIPGNSFGRE----------YIATQGPLPGTKD-------DFWRMVWEHNVYNIVMVTQCVEKGRVKCDQYWPTD--REPLYYGE---LVVHMLSESVLSEWIIREFKISR-EGQLSYPRIVRHFNYTVWPDHGVPETTQSLIQFVRTVRDYIDRAPTSGPTVVHCSAGVGRTGTFIVLDRALQQ-LDSRGTVDIYGSVRDLRLHRIHMVQTESQYMFLHQCVRDVL-RARKLRCEQEN 1886          

Query: 2949 STIVGVSVAV--FVIICLSIAIYFIIRYKRNKHVSEATN--------TAITHL--LPMDSKSPAAHEFHENY--EFMKQDSNGRLLDD---FRE-IKELAV-KLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSM---DYSI---FVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQ----AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEY 3980
            + I+ V VA+   ++I   I + +++R+K+ K     +N        T  T L  +P+ ++SP+ +  +     + ++++ N R+ DD   FRE    L V  ++        E N  KNR+ NI PY H+RV L     +  +D+INAS I   +   EK       N +IA QGP       K +TV DFWRMI E N   IV +T ++E  + KC+QYWP   +Q    Y     I V +   M   DY+I    +++V +VS  + +  VTQ H  +W D G P T   +      +K +  N      IVVHCSAGVGRTGTFI+ID  L  ++  + +++++  +  +R  RCQMVQT+ QY FI+  + E+
Sbjct:  233 TAIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLTNGRTEDTELQSVPLLARSPSTNRKYPPLPVDKLEEEMNRRMADDNKLFREEFNALPVCPIQASCDAASKEENKEKNRYVNILPYDHSRVHLSSLEGVPDSDFINASYI---NGYQEK-------NKFIAAQGP-------KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP---DQGCWTYGN---IRVSVEDVMVLVDYTIRKFCIQQVGDVSGKKPQRLVTQFHFTSWPDFGVPFTP--IGMLKFLKKVKTCNPQYAGPIVVHCSAGVGRTGTFIVIDAMLD-MMGAERKVDVFGFVTRIRAQRCQMVQTDMQYVFIFQALLEH 584          

Query: 3153 GRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ--SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            G L  +F+++  + ++ ++ +       N  KNR   I PY+ NRV +  K      DY+NAS I   + Q +          Y+A+QGP+         T+ DFWRMI E   C IV LT +EE G+EKC+QYW ++          D  I ++     +     + +   + + K  +V Q H   W + G PT  +  +   +A +K +Q   N  I VHCSAG GRTGTF  +   L R+ K +  ++++  + +LR  R  MVQT  QY F Y V+ EY+
Sbjct:  614 GGLEAEFKKLTSIKIQNDKMRTGNL-PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFI-DGYRQKDS---------YMASQGPL-------QHTIEDFWRMIWEWRSCSIVMLTELEERGQEKCAQYWSSD----GVMVCGDLSIELKREDECESYTVRDLLVTNNRENKARAVRQFHFHGWPEVGIPTDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERV-KAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 875          

Query: 2955 IVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAAHEFHE-NYEFMKQDSNGRLLDDFREIKELAVKLERQKV---IMFT-------------------EGNDAKNRFSNIKPYKHNRVKLLA-----KNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVF----NVSMDEKEISVTQLHMLAWKDHGCPT-TSEFLAFYSAYRKARQSNQA-IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDN 4019
            +VG  +AV  IIC+ IAI     YKR +  SEA   +    LP + + P+ H         +   + G        I +LA  LER K    + F+                   E N AKNR++N+  Y H+RV L A      +DYINA+ I     Q          N YIATQG + E       T GDFWRM+ E     IV +T++EE  + KC QYWPT   +          I V +  +++ + +  R F    N S +++E  V Q    AW DHG P   + FLAF    +     +   +VVHCSAGVGRTG FI+ID  L RI K +  ++IY ++  +R  R  MVQTE QY FI+  + E  V  G   +P  N
Sbjct: 1267 VVGPVLAVVFIICIVIAILL---YKRKRAESEARKGS----LPNNKEMPSHHPTDPVELRRLNFQTPGMASHPPIPIMDLADHLERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKAKNRYANVIAYDHSRVLLSAIDGIPGSDYINANYIDGYRKQ----------NAYIATQGSLPE-------TFGDFWRMVWEQRSANIVMMTKLEERSRVKCDQYWPTRGTETYGL------IQVTLLDTVELATYCVRTFALYKNGSSEKRE--VRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERI-KHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLE-AVTCGNTEVPARN 1621          

Query: 3237 NDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ---SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            N  KNR  NI PY+  RV L     +  +DYINAS I     Q            YIATQGP+ E  E       DFWRM+ E+N  ++V LT++ E G+EKC QYWP E + +  Y+  D      M        ++ R F V+   D +  +V Q     W + G P + E F+ F     K ++    +  I VHCSAGVGRTG FI +   L R ++ +  ++I+  +  LR  R  MVQTE QY F Y    EYL
Sbjct: 1666 NKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQ----------KAYIATQGPLAETTE-------DFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ------YILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLER-MRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYL 1901          

Query: 2964 VSVAVFVIICLSIAIYFIIRYKRNKHVSEATNT----------AITHLLPMDSKSP---------AAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSI---FVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQ----AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEY 3980
            V++A  ++I + I + +++R+++ KH    TN+          A    +P+ ++SP         A     E +     D N    ++F  +    ++   +      E N  KNR+ NI PY + RV L     +  +DYINAS +   +   EK       N +IA QG     + PK +T+ D+WRMI E N   IV +T ++E  + KC+QYWP   +Q    Y        ++   +DY+I    ++ V ++   +    +TQ H  +W D G P     +      +K +  N      IVVHCSAGVGRTGTFI+ID  L  +++ + +++++  +  +R  RCQMVQT+ QY FIY  + E+
Sbjct:  105 VALACILVIGVFIIVLYMLRFRKYKH--NGTNSLRLANGRGEDAEMQSMPLLARSPSTNRKYPPLAVDRLEEEFNRRSADDNKLFREEFNSLPSCPIQATCEAAS--KEENKEKNRYVNILPYDNFRVHLTSLEGVPDSDYINASYV---NGYQEK-------NKFIAAQG-----KGPKEETLNDYWRMIWELNTATIVMVTNLKERKECKCAQYWP---DQGCWTYGNLRVSVEDVTVLVDYTIRKFLIQVVGDIPNKKPPRLITQFHFTSWPDFGVPFAP--IGMLKFLKKVKTCNPPYAGPIVVHCSAGVGRTGTFIVIDAMLD-MIQTERKVDVFGFVTRIRAQRCQMVQTDMQYVFIYQALLEF 449          

Query: 3159 LLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ--SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            L D+F+++  + ++ E+ +       N  KNR   I PY  NRV +  K      DYIN S I        ++ + F     +A QGP+        QTV DFWRM+ E   C IV LT +EE G+EKC++YWPTE    ITY      I +E+     +  +  R F+VS   + K   + Q H   W + G P   +  ++  +A +K +Q   N  I VHCSAG GRTGTF  +   L R+ K +  ++++  + +LR  R  MVQT  QY F Y V+ EY+
Sbjct:  481 LEDEFKKLTTVKIQNEKMRTGNL-PANMKKNRVLQIIPYDFNRVIIPMKRGEEFTDYINGSFI-----DGYRQKDAF-----LAGQGPL-------QQTVEDFWRMVWEWRSCSIVMLTELEERGQEKCARYWPTE--GTITYGD----IIIELKQENSHDSYTVRDFSVSNTRENKSRQIRQFHFHGWPEIGIPEDGKGMISLIAAVQKQQQHTGNHPITVHCSAGAGRTGTFCALCTILERV-KTEGILDVFQTVKSLRTQRPHMVQTLEQYEFCYKVVQEYI 740          

Query: 3231 EGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVE-MNSSMDYSI---FVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQA----IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTES-------------------QYCFIYSVIHEY 3980
            E N  KNR+ NI PY  +RV+L     +  +DYINAS I          N     N +IA QGP       K +T+ DFWRMI E N   IV +T ++E    KCSQYWP     K  +      ++VE +   +DY+I    V+ V       +   VTQ H  +W D G P T   +      +K + SN +    IVVHCSAGVGRTGTFI+ID  L  I  E  R++++  +  +R  RCQMVQT+                    QY FIY  + E+
Sbjct:   57 EENKDKNRYINILPYDQSRVQLSPIESVPGSDYINASYI----------NGYREKNKFIAAQGP-------KEETINDFWRMIWEQNTSTIVMVTNLQERKHTKCSQYWP----DKGCWTYGSVRVSVEDITVLVDYTIRKFCVQLVGEGPGKHQARLVTQFHFTSWPDFGVPFTP--IGMLKFLKKVKTSNPSYSGPIVVHCSAGVGRTGTFIVIDAMLDMIQAE-QRVDVFGFVSRIRAQRCQMVQTDLQPLDCYLDSDFEQLASILIQYVFIYQALLEF 314          

Query: 2976 VFVIICLSIAIYFIIRYK-RNKHVSEATNTAITHLLPMDS---------------KSPAA-HEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSE----FLAFYSAYRKARQSNQAIVVHC----SAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            V +I CL+ A+  +I     N H   +  + +  L+  DS               ++P    +F + Y+  + DS     ++++E+  +  K +  +     E N  KNR++NI P+   RVKL     +  +DYINA+ I   H  S +         YIA QGP+   RE       DFWRM+ E  V  IV LT   E G+ KC  YWP +I      Y +   +      S +++I    V      +++ S+   H  AW DHG P T++    F+  +  +         IVVHC    SAGVGRTGTFI +D  L  I K+ + I+IY  + ++R  R  MVQTE QY FI+  I + L
Sbjct: 1058 VILIACLTTAMIVVIACAIENSHSVRSPRSYVELLVRRDSLTMHVIMEDTSNKKKRNPVPFSKFPDYYKKREADSGYLFSEEYQELSSVG-KGQAMEAATLAE-NRTKNRYTNILPFDVTRVKLASVEDIPHSDYINANYI-KGHSSSRE---------YIAAQGPLAGTRE-------DFWRMVWEQKVNQIVMLTNCVERGQPKCECYWPMDITP--VRYGDIGLVMEWDKPSPEWTIRHLVVKAQHKTDEKRSLYHFHFTAWPDHGVPDTTDSLTNFVRLFRTHVNTTNKGGPIVVHCRCGSSAGVGRTGTFISLDHLLQDIDKKPE-IDIYGIVHDMRMSRVLMVQTEMQYIFIHKCILKVL 1401          

Query: 3231 EGNDAKNRFSNIKPYKHNRVKLLAK--NDYINASKICSAHWQSEKENECFCSNI-YIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEI----SVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSN----QAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQY 3950
            E N  KNR+S+I PY HNRVKL  +  +DYINAS +           + + S+I YIA QGP+ EN      T GDFW+MI E    VIV +T+ EE GK KC QYWP     K  Y      + V +     Y+  V R  ++S  +        VT + +++W DHG P     L      R+    N     A+VVHCSAGVGR+GT+I +D  L R L+ +  +++Y  +  LR  R  MVQ E ++
Sbjct:  427 EYNTKKNRYSDILPYDHNRVKLSGEGESDYINASYV-----------DGYKSSIRYIAAQGPL-EN------TAGDFWQMIWEKKSSVIVMVTKCEEMGKVKCFQYWPHPDEDKRAYGD----VTVTIMDEKPYADIVIRTLSISHSKHRGFGAHWVTHVQLVSWPDHGVPEDPNLL--LKLRRRVNSFNGAGCTAVVVHCSAGVGRSGTYIGLD-CLVRQLENEGHVDVYGCVFRLRHQRPLMVQVEVRF 652          

Query: 3237 NDAKNRFSNIKPYKHNRVKLLAKND----YINASKI----CSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPT--EINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKARQ-----------SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLI 4001
            N  +NRF ++ PY+ NR++LL   D    Y+NAS+I        W             YIATQGP+         T  DFW+M+ E  V VI  +T+ EE GK K  +YWP     +  +TY        V      D+  +      +   +D  E +V  L    W DHGCP   + FL +    +  R+           +N  +VVHCSAGVGRTG  IL  E +   L+ ++++++ + L  LR  R  MVQT +QY F+Y  + ++L  + LI
Sbjct:  928 NHDRNRFKDVVPYEENRIELLPSKDNPTGYVNASRIQVTVSGEEWH------------YIATQGPL-------PSTCQDFWQMVWEEGVNVIAMVTQEEEGGKSKSHRYWPKLGSRHSAVTY----GKFKVTTKFRTDFGCYATTGLKLKHLLDGHERTVWHLQYTDWPDHGCPDHVQGFLGYLEEIKSVRRHTNNMLEASKPANPPVVVHCSAGVGRTGVVILT-EMMIACLEHNEKLDVPDVLAILRTQRMLMVQTITQYTFVYQALIQFLRSSRLI 1182          

Query: 3126 YEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKL--LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILEN---NVCVIVNLTRVEEHGKEKCSQYWP-------TEINQK---------ITYYSEDDPIN-VEMNSSMDYSIFVERVFNVSMDEKEISVTQLHML---AWKDHGCPTTSEFLAFYSAYRKARQS-NQAIVVHCSAGVGRTGTFILIDEEL----------------SRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIY 3962
            ++F++   +GRL    RE     V       +     NDA+NR+ NI PY+ NRV L  L+ NDYINAS +     +     +      YIATQGP         +T   FW+M   N   +  VIV +T + E+ +EKC QYWP         I  K         +T +  D  I  V ++   DY   V  +     D     V  +H      WKD   P     +    A+  +  S    I+VHCSAGVGRTGTFI +D  +                 R  +E  R  I   +L LR  R +MVQT+ Q+ FIY
Sbjct:   19 FKFIQNQEDGRL----REATNGTVNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGNDYINASYV-----KVNVPGQSIEPGYYIATQGPT-------RKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYT-VTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIY 322          

Query: 3243 AKNRFSNIKPYKHNRVKLLAK--------------------NDYINASKICSAHWQSEKENECFCSNI-------YIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYW 3542
            AKNR+ +I PY+H+RV +L K                    ++YINA+ +    +  E +N  F +         YIATQ P+         TV DF+  IL N V ++++LT   E+G EKC +YW
Sbjct:  529 AKNRYKDIFPYEHSRV-ILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVE-QNSSFQTTTTTTRRVRYIATQAPM-------PSTVHDFYTCILNNGVPLVLSLTNDFENGIEKCYRYW 646          

Query: 3225 FTEGNDA--KNRFSNIKPYKHNRVKL----------------------------------LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYW 3542
             TEG  +  KNR+SNI PY+H+RVKL                                     NDYINA+ +       + +        YIATQ P+         T+ DFW++I  N V VI++L   +E    K   YW
Sbjct:  402 LTEGIQSFTKNRYSNILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLTQINPDFK--------YIATQAPL-------PSTMDDFWKVITLNKVKVIISLNSDDELNLRKWDIYW 528          

Query: 3231 EGNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSE-FLAFYSAYRKA-RQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHE 3977
            + N  KNR+S++ PY HNRV L        +DYINAS I       +  N       YIATQGP+       A TV DFW+M+ E  V VIVNLTR+ + G  +C +YWP + ++  TY+  +  +  E     DY +    + N+   E   +VTQ H L+W D   PTT +  L F     K  R  +  IVVHCS GVGRTG +ILID  L+++++    I+I   + +LR  R  MV+T++Q+ F  + + E
Sbjct:   54 DKNVRKNRYSDVLPYDHNRVSLRETANATGSDYINASFITD----HDPRNPA-----YIATQGPL-------AHTVSDFWQMVWEQGVVVIVNLTRLSDLGLPQCHRYWPEDGHE--TYHIYEVHLVSEHIWCDDYLVRSFYLKNLQTSETR-TVTQFHFLSWPDLNVPTTPKPLLEFRRKVNKCFRGRSCPIVVHCSGGVGRTGCYILIDLVLNKMMRGAKEIDIAATVEHLRDQRPHMVKTKAQFEFALTAVAE 290          

Query: 3168 DFREIKELAVKLERQKVIMFTEG----NDAKNRFSNIKPYKHNRVKL-LAKND----YINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDE------KEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKAR----QSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIP 4010
            D++   E     E+ K + + +     N  KNRF+N+  Y H+RV L L +ND    YINA+ + + +            N YIATQGP+       A+T+ DFWRMI E N  VIV +T + E G+ KC+ YWPT+ N+K   +    P+ +       ++ +  R F +  ++      + + V Q H   W DHG P             K+          +VVHCSAGVGR+G FI+ID  + RI    D ++I+N L ++R  R  +VQ E QY FI+  + EY+    +I +P
Sbjct:   22 DYKFFMEFEGVHEKNKRLTWVQSQKPENQMKNRFANVVAYDHSRVVLSLTENDQSSHYINANYVDTYN----------AMNAYIATQGPL-------AKTISDFWRMIWEQNCRVIVMITNIIEKGRHKCAMYWPTK-NRKTENHG---PLTITFVQEETFAYYSIRTFEIKPNKDGTHYTQPMMVKQFHFTGWPDHGAPEPGFEFPVLDLIMKSTACVVPGTGPLVVHCSAGVGRSGAFIVIDSMIKRIHDNGD-LDIFNFLAHIRNQRNHLVQEECQYIFIHDTLAEYIACNFVISLP 299          

Query: 3222 MFTEGNDAKNRFSNI-KPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEI-SVTQLHMLAWKDHGCP----TTSEFLAFYSAYRKARQSNQ-------AIVVHCSAGVGRTGTFILIDEELSRILKE 3869
            +F E N  K    N    +  +RV+L  +     +DYINAS I           E F     IATQ P+         T  D+WRMI + N   IV L   +E  K+    Y P   +   T +  D  + +E  ++    I  +     + D   I  +   H L W +HG P    T  + ++    +    + N         IVVHC+ G+GRTG +  +     +I +E
Sbjct:  343 LFYECNLQKVTIDNFFSEFDSSRVRLYPRPGEEGSDYINASYI-----DGFTRREAF-----IATQHPL-------QSTTMDYWRMIWQENCRSIVMLLSEKEWDKDVFPSYLPAVHD---TAHFGDYEVTMESETARGDFIIRDLKLISTKDPSVIRQIRHFHFLHWPEHGQPWSGQTVLQLVSKVEEWESEVEKNSHQFDIIGPIVVHCNNGIGRTGVYCALHALWQQITQE 556          

Query: 3231 EGNDAKNRFSNIKPYKHNRVKLLAKN--DYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS--MDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQA-IVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            + N  KNR+ N+ PY+  RV+L   +  DYINA+     H +   +++ +    YIATQGP+         T  DFW+MI E  V V+  +T  +E GK KC +YWP   NQ +          V +    +Y  FV+R   V      K I +  L+ + W DHG P +   +  + AY ++  ++QA +VVHCSAG+GRTG  I +D  L  +++ D   +I   + +LR+ R  M+QT+ QY F Y    E L
Sbjct:   54 QANTDKNRYRNVLPYEATRVRLSGSSGEDYINAN-----HIRVLVDDDTYH---YIATQGPL-------PNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWPDNTNQPLKLGGR---FEVSLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQFVAYMRSLATSQAPVVVHCSAGIGRTGALIAVDVALG-LMERDKPFDINQTIRDLREQRQGMIQTKDQYIFCYKACLEVL 290          

Query: 3234 GNDAKNRFSNIKPYKHNRVKL-----LAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVS-MDEKE--ISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQ----AIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQA 3992
             N  KNR++NI  Y H+RV L     + ++DYINA+ I       +  N    S  +IA+QGP+ E       T  DFWRM+ E    +IV LT++EE G+ KC QYWP    +          + V  N +   S +V R F VS M E+E    V Q H  +W DHG P     L   S  R    +N      ++VHCSAGVGRTGTFI +D  L R  +E   I+++  +  +R  R  MVQTESQY F    IH+ LV+A
Sbjct:   45 ANKYKNRYANIVAYDHSRVLLTPLEGVLESDYINANYI-------DGYNR---SGAFIASQGPLPE-------TFDDFWRMVWEQGSAIIVMLTQLEERGRRKCDQYWPDRGTRNY------GALRVTANETFHMSYYVLRTFLVSHMQEEEEPRQVRQYHYTSWPDHGVPAHPAPL--LSMVRTVSSANPPTAGPMIVHCSAGVGRTGTFITLDSMLQRAAQEGT-IDVFGFVRQMRNKRNLMVQTESQYVF----IHDALVEA 279          

Query: 3237 NDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEIS--VTQLHMLAWKDHGCPTTS-EFLAFYSAYRKARQ--SNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            N AKNR++NI PY+  RV L  +     +DYINAS I   H              YIATQ P+        +T  DFWRM+ E    VIV LTR EE GK KC +YWP++ ++        D I VE+   + YS +V R F+++  E++ S  V Q     W D G P +    +       K +Q   N  I VHCS GVGRTG F  +   + R+ K +  I+++  + +LR  R  MVQT+ QY F Y+ I EYL
Sbjct:  336 NAAKNRYANILPYERTRVALHMRPGEVGSDYINASFIDGNH----------RLKAYIATQAPV-------PRTFEDFWRMLWEQESAVIVMLTREEEAGKLKCHRYWPSDGSRLY------DKILVELTEELTYSDYVLRQFSLTHTEEKSSRIVRQFQCTDWPDSGLPESGVGLIDLIGQVEKWQQQSGNTCITVHCSGGVGRTGVFCAVSILIERV-KAEGLIDVFQTVQHLRLQRPAMVQTKDQYEFCYTTIQEYL 570          

Query: 3225 FTEGNDAKNRFSNIKPYKHNRVKLLA-----KNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNV--SMDEKEISVTQLHMLAWKDHGCP-TTSEFLAFYSAYRKARQSN-----QAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHE 3977
              + N  KNR++NI  + H RV L        +DYINA+ +     Q E          YIA QGP+ E       T  DFWRM+ E N  VIV +T  EE G+ KC QYWP+  +Q          I+V M S+++ S +  R F V  S   +E  V Q H  AW DHG P + +  L F    RK+   N       +VVHCSAGVGRTGT+++ID +L RI  E   +++YN ++ LR  R  MVQ E QY  I+ V+ E
Sbjct:   40 LNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQRE----------YIAAQGPLPE-------TCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGV------IHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNF---VRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEAT-VDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE 276          

Query: 3237 NDAKNRFSNIKPYKHNRVKLLAK-----NDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEIS--VTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSN---QAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            N  KNR++N+ PY   RV+L  +     +DYINA+ I          +       +IATQ PI +       T+ DFWRMI E + C IV L++  E GK K  +YWP +    I        + VEM     +  ++ R F V+  ++  S  V Q    AW D G P +   L       +  Q     Q   VHCSAGVGRTG F  +   + R LK +  ++++  +  LR+ R  MVQT+ QY F Y  + EYL
Sbjct:  334 NKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYI----------DGYMSKKAFIATQAPIPD-------TIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSI------GNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIER-LKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL 568          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNY-WLTCKNESVIYNDNI------TSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSP--------PKPKRALKRNTNPKANWQNEE-YIVGNN---LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVS--EA----TNTAITHLL--------------PMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLL-----AKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTT-SEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            P   ++   + +    +  +++PP E NG I +Y  L  + E +I N ++       +T     E ++    Y+ Q+SA    G+      F I      P  +     P AM          +    +  P   +S++ G I    ++++E+ +                   E IT     + +R +P          P  ++K+      +++ EE Y++G N   L  N +DH  NGPLK  T+Y+  FRA    G  T        +V       G  +     I L + + F +  K     S  EA    T   +  L+              P++ KS     F ++ E +  + N +  ++F E+ +L   L      +    N +KNRF NIKPY +NRVKLL     A +D+INAS +              C N +IATQGP+         TV DFWRMI E     I  LT+  E G+ +C +YWP E N+ +T +S+     V   +  D++I   R   V      I V   +  +W +HG P + S F+ F  A R  R  N  I VHCSAGVGRTG FI +D  +  + ++ + ++IY  +  LR  R  MVQ  +QY F++    E L   G
Sbjct: 1444 PPKNVNVTAIPEEVKSVTVSFSPPEEPNGIITDYVALVYEKEKLIKNISLRIIQTENNTLTADVEGLKGGHNYSIQISAKNGAGWSPLSQHFQITTGIKAP--SKPTQTPQAMLGNGGVAMVTHKTITVRKPACFYSDDNGPIAKIQVIVAESGDQ------------------ENITNWRSAFYLRPAPYLTDEGFYNPPCSSVKKTAAVNTHFRGEEGYVIGGNNACLEQNNTDHFCNGPLKPNTVYVFKFRATNIRGQYT-------DSVYSEHVRTGTPIGSETQIILGVLLSFFLHKKEGGTYSPREAEIIETKCKLDQLIAVADMELKQEKLNRPVNKKS-----FLQHVEDLCANDNSKFQEEFAELPKLLQDLATTDADL--PWNKSKNRFPNIKPYNNNRVKLLSEPGTAGSDFINASFVSG----------YLCPNEFIATQGPL-------PGTVADFWRMIWETGTRSIAMLTQCYEKGRIRCHKYWP-EDNKPMTVFSDILISKVSEEAFPDWTI---RTLKVEKHGHYILVKHFNYTSWPEHGVPESCSTFIKFVKAIRSHRHDNSTIAVHCSAGVGRTGVFIALDHLIQHV-RDHEFVDIYGLVAELRSERMCMVQNLAQYIFLHQCTLELLNNKG 2038          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNY-WLTCKNESVIYNDNI------TSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITL--PYSHFSNNGGTIQMFTLVISET----RNNIVGNASITSLQYQNVAYGECI-------TKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNN---LLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIE---RKTAVNKIST-----IVGVSVAV------FVIICLSIAIYF------------------------IIRYKRNKHVSEATNTAITH---LLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLL-----AKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTT-SEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAG 3995
            P   ++   + +    +  +++PP E NG I +Y  L  + E +I N ++       +T     E ++    Y+ Q+SA    G+      F I      P  +     P AM   N  VA   T   IT+  P   +S++ G I    ++++E+    + NI    S   L+       E          K T          +P+     +         E Y++G N   L  N +DH  NGPLK  T+Y+  FRA    G  T        R  + + + T     I+GV ++        +IIC+S+ ++                         +I     +   E  N  +++   L P++ KS     F ++ E +  + N +  ++F E+ +L   L      +    N +KNRF NIKPY +NRVKLL     A +D+INAS +              C N +IATQGP+         TV DFWRMI E     I  LT+  E G+ +C +YWP E N+ +T +S+     V   +  D++I   R   V      I V   +  +W +HG P + S F+ F  A R  R  N  I VHCSAGVGRTG FI +D  +  + ++ + ++IY  +  LR  R  MVQ  +QY F++    E L   G
Sbjct: 1333 PPKNVNVTAIPEEVKSVTVSFSPPEEPNGIITDYVALVYEKEKLIKNISLRIIQTENNTLTADVEGLKGGHNYSIQISAKNGAGWSPLSQHFQITTGIKAP--SKPTQTPQAMLG-NGGVA-MVTHKTITVRKPACFYSDDNGPIAKIQVIVAESGVRDQENITNWRSAFYLRPAPYLTDEGFYNPPCSSVKKTAAVNTHFRGGQPESGDGSSLVRFNQTTEEGYVIGGNNACLEQNNTDHFCNGPLKPNTVYVFKFRATNIRGQYTDSVYSEHVRTASADGLLTREEQIILGVLLSFFLALFFIIIICVSVKLHQHKKEGGTYSPREAEIIETKCKLDQLIAVADMELKQEKLNRLLSYRKSLKPVNKKS-----FLQHVEDLCANDNSKFQEEFAELPKLLQDLATTDADL--PWNKSKNRFPNIKPYNNNRVKLLSEPGTAGSDFINASFVSG----------YLCPNEFIATQGPL-------PGTVADFWRMIWETGTRSIAMLTQCYEKGRIRCHKYWP-EDNKPMTVFSDILISKVSEEAFPDWTI---RTLKVEKHGHYILVKHFNYTSWPEHGVPESCSTFIKFVKAIRSHRHDNSTIAVHCSAGVGRTGVFIALDHLIQHV-RDHEFVDIYGLVAELRSERMCMVQNLAQYIFLHQCTLELLNNKG 1975          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNE---SVIYN----DNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRN----------------NIVGNASITSLQ--YQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGN----KSDHNS--NGPLKSGTLYIIGFRAYT-----------------SAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSE--------------ATNTAITHLLPMDSKSPAA-HEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKND-----YINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEK---EISVTQLHMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            P  VL   C  QS T I C+W PP        +Y + C ++   +V+Y+     + TS  +T  +      +Y   +SA T+          +I  P A+P    +      +S  +I           +   S FS+  G I+ FT+V++E++                 + + N+SI S Q  Y +    E +  N  V+ I L                          G   LG      SD N   +GPLK  T Y +  RA+T                 +  ++++  +    ++N +  I G+S  +F+I  + +    ++  +R   V E              +T T +       + SP     F  ++  ++ DS+  L +++ ++K++         ++    N  KNR++NI PY   RVKL   +D     YINAS I   +++ E          YIATQGP+   ++       DFW+M+ E NV  +V +T+  E G+ KC  YWP   +Q   YY +   + V+M S    S +  R F +  +E+      V Q H   W DHG P  +    +F+     Y      +   VVHCSAGVGR+GTFI++D  L + L   D ++IY  + +LR  R  MVQTE QY +++  + + L
Sbjct: 1037 PGRVLGLHCRPQSSTSISCSWTPP---EADFDSYNIECVHQDSRTVVYSRRTGKDSTSYVITQLDPHRHYTVYVKVISAGTTSSEVEDSIVTMIDRPPALPIGTRVSERSTVVSTCSI---------LFSFNCSWFSDTNGAIKFFTVVVTESKGVEDVLPDQYHPLPSYRDYISNSSIKSYQTSYFSSYCSESLDSNAHVFNISLGS------------------------GMEPLGGPCEPSSDLNQFCDGPLKPRTSYRLSIRAFTQLFHEDSKDIGTFSPLFTDTYLSLPIVTETESLNGV--IGGISAGLFLIAVVVVITALLVCRRRVGRVGEERPVFGMSQRRERLSTGTQLGIRGNRRTSSPIRIMNFESHFNKLQADSHYLLSEEYEDLKDVGRNQPLDSALL--PENRGKNRYNNILPYDSTRVKLSYVDDDPCSDYINASYIPGNNFRRE----------YIATQGPLPGTKD-------DFWKMVWEQNVHNVVMVTQCVEKGRVKCDHYWP--FDQDPLYYGD---LIVQMLSESVLSEWTIREFRICSEEQLSFSRLVRQFHYTVWPDHGIPDNTQSLIQFVRTVRDYVNRSPGSGPTVVHCSAGVGRSGTFIVLDRVLQQ-LDVRDTVDIYGAVFDLRLHRSHMVQTEGQYSYLHHCVRDVL 1650          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNE---SVIYN----DNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRN----------------NIVGNASITSLQ--YQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSN------GPLKSGTLYIIGFRAYT-----------------SAGFVTVGFIERKTAVNKISTIVGVSVAVFVI-ICLSIAIYFIIRYK------------RNKHVSEATNTAITHLLPMDSKSPAA-HEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKND-----YINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEK---EISVTQLHMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYL 3983
            P  VL   C  QS T I C+W PP        +Y + C ++   +V+Y+     + TS  +T  +      +Y   +SA T+          +I  P A+P    +      +S  +I           +   S FS+  G I+ FT+V++E++                 + + N+SI S Q  Y +    E +  N  V+ I L                          G   LG   + +S+      GPLK  T Y +  RA+T                 +  ++++  +    ++N +  I G+S  +F+I + + I    + R +            R + +S  T   I         SP     F  ++  ++ DS+  L +++ ++K++         ++    N  KNR++NI PY   RVKL   +D     YINAS I   +++ E          YIATQGP+   ++       DFW+M+ E NV  +V +T+  E G+ KC  YWP   +Q   YY +   + V+M S    S +  R F +  +E+      V Q H   W DHG P  +    +F+     Y      +   VVHCSAGVGR+GTFI++D  L + L   D ++IY  + +LR  R  MVQTE QY +++  + + L
Sbjct: 1245 PGRVLGLHCRPQSSTSISCSWTPP---EADFDSYNIECVHQDSRTVVYSRRTGKDSTSYVITQLDPHRHYTVYVKVISAGTTSSEVEDSIVTMIDRPPALPIGTRVSERSTVVSTCSI---------LFSFNCSWFSDTNGAIKFFTVVVTESKGVEDVLPDQYHPLPSYRDYISNSSIKSYQTSYFSSYCSESLDSNAHVFNISLGS------------------------GMEPLGGPCEPSSDLNQFCDGPLKPRTSYRLSIRAFTQLFHEDSKDIGTFSPLFTDTYLSLPIVTETESLNGV--IGGISAGLFLIAVVVVITALLVCRRRVGRERPVFGMSQRRERLSTGTQLGI-------RGSPIRIMNFESHFNKLQADSHYLLSEEYEDLKDVGRNQPLDSALL--PENRGKNRYNNILPYDSTRVKLSYVDDDPCSDYINASYIPGNNFRRE----------YIATQGPLPGTKD-------DFWKMVWEQNVHNVVMVTQCVEKGRVKCDHYWP--FDQDPLYYGD---LIVQMLSESVLSEWTIREFRICSEEQLSFSRLVRQFHYTVWPDHGIPDNTQSLIQFVRTVRDYVNRSPGSGPTVVHCSAGVGRSGTFIVLDRVLQQ-LDVRDTVDIYGAVFDLRLHRSHMVQTEGQYSYLHHCVRDVL 1850          

Query: 2178 PSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNE---SVIYN----DNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRN----------------NIVGNASITSLQ--YQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSN------GPLKSGTLYIIGFRAYT-----------------SAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSE--------------ATNTAITHLLPMDSKSPAA-HEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKND-----YINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEK---EISVTQLHMLAWKDHGCPTTS----EFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTE 3941
            P  VL   C  QS T I C+W PP        +Y + C ++   +V+Y+     + TS  +T  +      +Y   +SA T+          +I  P A+P    +      +S  +I           +   S FS+  G I+ FT+V++E++                 + + N+SI S Q  Y +    E +  N  V+ I L                          G   LG   + +S+      GPLK  T Y +  RA+T                 +  ++++  +    ++N +  I G+S  +F+I  + +    ++  +R   V E              +T T     L +   SP     F  ++  ++ DS+  L +++ ++K++         ++    N  KNR++NI PY   RVKL   +D     YINAS I   +++ E          YIATQGP+   ++       DFW+M+ E NV  +V +T+  E G+ KC  YWP   +Q   YY +   + V+M S    S +  R F +  +E+      V Q H   W DHG P  +    +F+     Y      +   VVHCSAGVGR+GTFI++D  L + L   D ++IY  + +LR  R  MVQTE
Sbjct: 1145 PGRVLGLHCRPQSSTSISCSWTPP---EADFDSYNIECVHQDSRTVVYSRRTGKDSTSYVITQLDPHRHYTVYVKVISAGTTSSEVEDSIVTMIDRPPALPIGTRVSERSTVVSTCSI---------LFSFNCSWFSDTNGAIKFFTVVVTESKGVEDVLPDQYHPLPSYRDYISNSSIKSYQTSYFSSYCSESLDSNAHVFNISLGS------------------------GMEPLGGPCEPSSDLNQFCDGPLKPRTSYRLSIRAFTQLFHEDSKDIGTFSPLFTDTYLSLPIVTETESLNGV--IGGISAGLFLIAVVVVITALLVCRRRVGRVGEERPVFGMSQRRERLSTGTQFVVKLFLIISSPIRIMNFESHFNKLQADSHYLLSEEYEDLKDVGRNQPLDSALL--PENRGKNRYNNILPYDSTRVKLSYVDDDPCSDYINASYIPGNNFRRE----------YIATQGPLPGTKD-------DFWKMVWEQNVHNVVMVTQCVEKGRVKCDHYWP--FDQDPLYYGD---LIVQMLSESVLSEWTIREFRICSEEQLSFSRLVRQFHYTVWPDHGIPDNTQSLIQFVRTVRDYVNRSPGSGPTVVHCSAGVGRSGTFIVLDRVLQQ-LDVRDTVDIYGAVFDLRLHRSHMVQTE 1744          

Query:  105 MVTVRFTPFTLLCSILLFYSAYSDNASTVNQNTSPSTLSSTETVQMKDIQQTNISSSEILQTYTYQSSESKTTDIRSSPMEISSRFTPMSTVVTEPAGSESSIPIKTFPTYQSTVTYLYPGVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQSIVDKSQIKIVWSYPIVHTINYKYDIQVYNGTFSYKDELRGGSYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSISSSVTGNNIILTWTFGEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDSNLFRQSYENPIFVE 4073
            MVTVRFTPF LLCSILLFYSAYSDNASTVNQNTS STLSSTETVQMKD QQTNISSSEILQTYTYQSSESKTTDIRSSPMEISSRFTPMSTVVTEPAGSESSIPIKTFPTYQSTVTYLYPGVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFN SNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDC PNISVPPWPDNSI NCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPP+NKTMEIIKYSIWIQRSDNNQCVLKTEMNC D FNNVSQSSHM++NITECYSI GLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCG GPISNISVTTPQYQPDPVTNLQSIVDKSQIKIVWSYPIVHTINYKY IQVYNGTFSYKDELRGGSYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSISSSVTGNNIILTWTFGEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPFSFKKNSSVFSKGNSLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYW+TCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKV DEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKN CVYEIRL PPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPA HEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNRED+NLFRQSYENPIFVE
Sbjct:    1 MVTVRFTPFALLCSILLFYSAYSDNASTVNQNTSLSTLSSTETVQMKDNQQTNISSSEILQTYTYQSSESKTTDIRSSPMEISSRFTPMSTVVTEPAGSESSIPIKTFPTYQSTVTYLYPGVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFNFSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCTPNISVPPWPDNSIINCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPENKTMEIIKYSIWIQRSDNNQCVLKTEMNCMDCFNNVSQSSHMNSNITECYSISGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGCGPISNISVTTPQYQPDPVTNLQSIVDKSQIKIVWSYPIVHTINYKYGIQVYNGTFSYKDELRGGSYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSISSSVTGNNIILTWTFGEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPFSFKKNSSVFSKGNSLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWITCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVTDEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNPCVYEIRLLPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAVHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDTNLFRQSYENPIFVE 1323          

Query:  240 MKDIQQTNISSSEILQTYTYQSSESKTTDIRSSPMEISSRFTPMSTVVTEPAGSESSIPIKTFPTYQSTVTYLYPGVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQSIVDKSQIKIVWSYPIVHTINYKYDIQVYNGTFSYKDELRGGSYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSISSSVTGNNIILTWTFGEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPXXXXXXXXXXXXXXXLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDSNLFRQSYENPIFVE 4073
            MKD QQTNISSSEILQTYTYQSSESKTTDIRSSPMEISSRFTPMSTVVTEPAGSESSIPIKTFPTYQSTVTYLYPGVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFN SNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDC PNISVPPWPDNSI NCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPP+NKTMEIIKYSIWIQRSDNNQCVLKTEMNC D FNNVSQSSHM++NITECYSI GLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCG GPISNISVTTPQYQPDPVTNLQSIVDKSQIKIVWSYPIVHTINYKY IQVYNGTFSYKDELRGGSYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSISSSVTGNNIILTWTFGEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPFSFKKNSSVFSKGNSLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYW+TCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKV DEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKN CVYEIRL PPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPA HEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNRED+NLFRQSYENPIFVE
Sbjct:    1 MKDNQQTNISSSEILQTYTYQSSESKTTDIRSSPMEISSRFTPMSTVVTEPAGSESSIPIKTFPTYQSTVTYLYPGVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFNFSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCTPNISVPPWPDNSIINCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPENKTMEIIKYSIWIQRSDNNQCVLKTEMNCMDCFNNVSQSSHMNSNITECYSISGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGCGPISNISVTTPQYQPDPVTNLQSIVDKSQIKIVWSYPIVHTINYKYGIQVYNGTFSYKDELRGGSYNFSSVSLEFCTYYTLCVMVIDDYKVPSVTRCISNTTGLSFVAINSISSSVTGNNIILTWTFGEQSNCLVQFNVATTVPENINVTNNKYEMRNLKYATPYTIKVTPFSFKKNSSVFSKGNSLDQVAITGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWITCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVTDEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNPCVYEIRLLPPKPKRALKRNTNPKANWQNEEYIVGNNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLSIAIYFIIRYKRNKHVSEATNTAITHLLPMDSKSPAVHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENECFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNREDTNLFRQSYENPIFVE 1278          

Query: 2163 TGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVG-NNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLS-----IAIYFIIRYKRNKHVSEATNTAITHLLPMDS-KSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENE-CFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNR---EDSNLFRQSYENPIFVE 4073
            T + +   V +F C N S+  I C+W  P + NG IL+Y +TCK  SV++N  +T T + I+  ++ DILY  ++SASTS+G G  ++  + I PS  P + N   IPD +      V D   Q A+TLPY+HF+N+ G I+ FTLVIS   +    N++IT   Y ++                +  P+P   + R     + WQ+  +++G      N S +  NGPL S T YIIGFR YT+AGF T G I  +TA+N       + V  F+ + LS      A YF  RY+R              + P D+ KSP    FH ++EFMK+DSNGRL+D F++IK+   +LE Q V++F+ GN  KNR+ NIKPY+HNRVKL   +DYINAS+IC  HW ++     C C++ YIATQGP+GE+REPK  T+GDFWRM+LENNVC+IVNLTR EE+GKEKCSQYWP + N +I + S DD + V M +S + SIF ERV  VSM++ E +V QLHM +W DH CPTTS+F+ FY+AY +++  ++AI+VHCSAGVGRTG+FILIDEELSRI K  D++EIYN L NLRKCRCQMVQTESQYCFIY++IHE L+Q GL ++P  +R     S    QSY NPIF E
Sbjct:  915 TNQYISGPVSNFNCYNSSFNSIFCSWGFPSKANGVILSYTITCKASSVVFNKTLTDTWINITSSIKPDILYILEISASTSIGAGEKIYFNITISPSPFPFVINASKIPDVLRNSIATVNDSRYQLAVTLPYNHFNNDLGIIRKFTLVISTNDDIYPRNSTITKSSYSDL----------------ILLPEPGSQITRKKRAISEWQSRPFVIGATQSCSNSSSNTCNGPLLSATAYIIGFRVYTTAGFTTEGVITVRTAINW-----AILVGFFIFLLLSGGIGFAAFYFYRRYRRLNRSDSDIVVIHGDICPDDNDKSPLTFNFHAHFEFMKRDSNGRLIDQFQDIKQQVKQLETQNVLVFSAGNIHKNRYGNIKPYQHNRVKLNKLDDYINASRICVRHWNTDLNGSPCNCTDYYIATQGPLGEDREPKVSTIGDFWRMVLENNVCIIVNLTRSEENGKEKCSQYWPDKNNDRIAFSSGDDLVEVIMTNSRENSIFTERVLTVSMNKYEKTVKQLHMTSWLDHSCPTTSDFMEFYAAYIRSKVPSEAIIVHCSAGVGRTGSFILIDEELSRIEKRTDKVEIYNTLFNLRKCRCQMVQTESQYCFIYTIIHECLIQRGLSKVPERDRPANPQSISHSQSYINPIFAE 1541          

Query:  465 GVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYG---CYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPH-QIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQSIVDK-SQIKIVWSYP-------IVHTINYKYDIQVYNGTFS 1754
            G + NLS +S+FP  PL+I+WE P   NGEIVQY + V KT  N +CVLTM LNCTDC+ N+SVP +PD     CY ING  FNS+N+ F + + D +I PYT Y I+V + N +GWGNL S   +TSQY SGPV   S+T  +P   + I W  P   NG+IVQYFIWV++ N +CVLTMS+NCTDCK N+SVP  P+NS +NC   +G  FN   +  S+ I D KILP   Y +NIR LNGYGWGN +          S  I NLSV  SFP  PL+I W+PP     EI++Y IW+Q + NN+CVL    NCTD  NN+S  +  D +   CY+I GL FNS +  FS+ I D  I P + Y +NVR L   GWG  S+ ++ T QY   PV+N        + I   W +P       + +TI  K    V+N T +
Sbjct:  531 GSIMNLSVASSFPSFPLSITWEPPGVANGEIVQYLIWVQKT--NNECVLTMSLNCTDCKNNLSVPAMPDNSTDSCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINVRSLNGYGWGNLSSKTIQTSQYISGPVTNLSVTSSFPSFPLSIIWSPPVVSNGEIVQYFIWVQNTNNECVLTMSLNCTDCKNNLSVPRIPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYTSGSIMNLSVASSFPSFPLSITWEPPGVANGEIVQYLIWVQNT-NNECVLTVSFNCTDCKNNLSVPAMPDNSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINVRSLNGYGWGNSSSKTIQTNQYISGPVSNFNCYNSSFNSIFCSWGFPSKANGVILSYTITCKASSVVFNKTLT 969          

Query:  465 GVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPH-QIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQ--SIVDKSQIKIVWSYPIV 1703
            G V+NLS +S FPL PL+I+W  P   NGEIVQY + V KT  N +CVLTM LNCTDC+  +S+P      CY ING  FNS+++ F + + D +I  YT Y I++ + N +GWGNL S   +T+QY SGPV   ++   +P   + I W  P   NG+IVQYFIWV++ N +CVLTMS+NCTDCK N+SVP  P+NS +NC   +G  FN   +  S+ I D KILP   Y +NIR LNGYGWGN +          S  I NLSV  SFP  PL+I W+PP     EI++Y IW+Q++ NN+CVL   +NCTD  NN+S  +  D +   CY+I GL FNS +  FS+ I D  I P + Y +NVR L   GWG +S+ ++ T QY   PVTNL   S      + I+WS P+V
Sbjct:  274 GPVTNLSVTSLFPLSPLSITWAPPGVTNGEIVQYLIWVQKT--NNECVLTMSLNCTDCKNKISMPDNSTNACYTINGLNFNSNDKSFSMTINDGKILSYTNYTINIRSLNGYGWGNLSSKTIKTNQYISGPVTNVTVNSSFPSFPLSITWAPPGVTNGEIVQYFIWVQNTNNECVLTMSLNCTDCKNNLSVPRMPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYTSGSIMNLSVASSFPSFPLSITWEPPGVANGEIVQYLIWVQKT-NNECVLTMSLNCTDCKNNLSVPAMPDNSTDSCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINVRSLNGYGWGNLSSKTIQTSQYISGPVTNLSVTSSFPSFPLSIIWSPPVV 686          

Query:  465 GVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYG---CYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPH-QIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQ--SIVDKSQIKIVWSYPIV 1703
            G V+N++ +S+FP  PL+I+W  P   NGEIVQY++ V  T  N +CVLTM LNCTDC+ N+SVP +P+     CY ING  FNS+N+ F + + D +I PYT Y I++ + N +GWGN  S   +T QYTSG +   S+   +P   + I W  P   NG+IVQY IWV+  N +CVLTMS+NCTDCK N+SVP  PDNS ++C   +G  FN   +  S+ I D KILP   Y +N+R LNGYGWGN++      S  +S P++NLSV  SFP  PL+I W PP     EI++Y IW+Q + NN+CVL   +NCTD  NN+S     + +   CY+I GL FNS +  FS+ I D  I P + Y +N+R L   GWG  S+ ++ T QY    + NL   S      + I W  P V
Sbjct:  401 GPVTNVTVNSSFPSFPLSITWAPPGVTNGEIVQYFIWVQNT--NNECVLTMSLNCTDCKNNLSVPRMPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYTSGSIMNLSVASSFPSFPLSITWEPPGVANGEIVQYLIWVQKTNNECVLTMSLNCTDCKNNLSVPAMPDNSTDSCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINVRSLNGYGWGNLSSKTIQTSQYISGPVTNLSVTSSFPSFPLSIIWSPPVVSNGEIVQYFIWVQNT-NNECVLTMSLNCTDCKNNLSVPRIPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYTSGSIMNLSVASSFPSFPLSITWEPPGV 816          

Query:  471 VSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSV--PYLPD---YGCYQINGPT--FNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYP-HQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQ--SIVDKSQIKIVWSYPIV 1703
            V NL+ +S + ++ L I W+RP    G I+ Y V +     +  C+    L+C+DC+++       L D     C QIN  +   +++++   +   D  ++P T Y +   A N FGWG+  S+   T Q+ SGPV   S+T ++P   + I W  P   NG+IVQY IWV+  N +CVLTMS+NCTDCK  IS+P   DNS N C   +G  FN   +  S+ I D KIL    Y +NIR LNGYGWGN++      +  +S P++N++V  SFP  PL+I W PP     EI++Y IW+Q + NN+CVL   +NCTD  NN+S     + +   CY+I GL FNS +  FS+ I D  I P + Y +N+R L   GWG  S+ ++ T QY    + NL   S      + I W  P V
Sbjct:  140 VQNLNGTSKWGVNNLLIEWDRPSAIGGTILAYLVTIGGQLNDSVCIKRWLLSCSDCQESAQAIGQSLQDPSVRNCSQINNASSFVSTADKHLSLATNDSDVKPATSYLVIATALNEFGWGDAQSISLLTDQFISGPVTNLSVTSLFPLSPLSITWAPPGVTNGEIVQYLIWVQKTNNECVLTMSLNCTDCKNKISMP---DNSTNACYTINGLNFNSNDKSFSMTINDGKILSYTNYTINIRSLNGYGWGNLSSKTIKTNQYISGPVTNVTVNSSFPSFPLSITWAPPGVTNGEIVQYFIWVQNT-NNECVLTMSLNCTDCKNNLSVPRMPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYTSGSIMNLSVASSFPSFPLSITWEPPGV 556          

Query: 2163 TGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVG-NNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLS-----IAIYFIIRYKRNKHVSEATNTAITHLLPMDS-KSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENE-CFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNR---EDSNLFRQSYENPIFVE 4073
            T + +   V +F C N S+  I C+W  P + NG IL+Y +TCK  SV++N  +T T + I+  ++ DILY  ++SASTS+G G  ++  + I PS  P + N   IPD +      V D   Q A+TLPY+HF+N+ G I+ FTLVIS   +    N++IT   Y ++                +  P+P   + R     + WQ+  +++G      N S +  NGPL S T YIIGFR YT+AGF T G I  +TA+N       + V  F+ + LS      A YF  RY+R              + P D+ KSP    FH ++EFMK+DSNGRL+D F++IK+   +LE Q V++F+ GN  KNR+ NIKPY+HNRVKL   +DYINAS+IC  HW ++     C C++ YIATQGP+GE+REPK  T+GDFWRM+LENNVC+IVNLTR EE+GKEKCSQYWP + N +I + S DD + V M +S + SIF ERV  VSM++ E +V QLHM +W DH CPTTS+F+ FY+AY +++  ++AI+VHCSAGVGRTG+FILIDEELSRI K  D++EIYN L NLRKCRCQMVQTESQYCFIY++IHE L+Q GL ++P  +R     S    QSY NPIF E
Sbjct:  785 TNQYISGPVSNFNCYNSSFNSIFCSWGFPSKANGVILSYTITCKASSVVFNKTLTDTWINITSSIKPDILYILEISASTSIGAGEKIYFNITISPSPFPFVINASKIPDVLRNSIATVNDSRYQLAVTLPYNHFNNDLGIIRKFTLVISTNDDIYPRNSTITKSSYSDL----------------ILLPEPGSQITRKKRAISEWQSRPFVIGATQSCSNSSSNTCNGPLLSATAYIIGFRVYTTAGFTTEGVITVRTAINW-----AILVGFFIFLLLSGGIGFAAFYFYRRYRRLNRSDSDIVVIHGDICPDDNDKSPLTFNFHAHFEFMKRDSNGRLIDQFQDIKQQVKQLETQNVLVFSAGNIHKNRYGNIKPYQHNRVKLNKLDDYINASRICVRHWNTDLNGSPCNCTDYYIATQGPLGEDREPKVSTIGDFWRMVLENNVCIIVNLTRSEENGKEKCSQYWPDKNNDRIAFSSGDDLVEVIMTNSRENSIFTERVLTVSMNKYEKTVKQLHMTSWLDHSCPTTSDFMEFYAAYIRSKVPSEAIIVHCSAGVGRTGSFILIDEELSRIEKRTDKVEIYNTLFNLRKCRCQMVQTESQYCFIYTIIHECLIQRGLSKVPERDRPANPQSISHSQSYINPIFAE 1411          

Query:  465 GVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYG---CYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPH-QIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQSIVDK-SQIKIVWSYP-------IVHTINYKYDIQVYNGTFS 1754
            G V+N++ +S+FP  PL+I+W  P   NGEIVQY++ V  T  N +CVLTM LNCTDC+ N+SVP +P+     CY ING  FNS+N+ F + + D +I PYT Y I++ + N +GWGN  S   +T QY SGPV   S+T  +P   + I W  P   NG+IVQYFIWV++ N +CVLTMS+NCTDCK N+SVP  P+NS +NC   +G  FN   +  S+ I D KILP   Y +NIR LNGYGWGN +          S  I NLSV  SFP  PL+I W+PP     EI++Y IW+Q + NN+CVL    NCTD  NN+S  +  D +   CY+I GL FNS +  FS+ I D  I P + Y +NVR L   GWG  S+ ++ T QY   PV+N        + I   W +P       + +TI  K    V+N T +
Sbjct:  401 GPVTNVTVNSSFPSFPLSITWAPPGVTNGEIVQYFIWVQNT--NNECVLTMSLNCTDCKNNLSVPRMPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYISGPVTNLSVTSSFPSFPLSIIWSPPVVSNGEIVQYFIWVQNTNNECVLTMSLNCTDCKNNLSVPRIPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYTSGSIMNLSVASSFPSFPLSITWEPPGVANGEIVQYLIWVQNT-NNECVLTVSFNCTDCKNNLSVPAMPDNSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINVRSLNGYGWGNSSSKTIQTNQYISGPVSNFNCYNSSFNSIFCSWGFPSKANGVILSYTITCKASSVVFNKTLT 839          

Query:  465 GVVSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYGCYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPH-QIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQ--SIVDKSQIKIVWSYPIV 1703
            G V+NLS +S FPL PL+I+W  P   NGEIVQY + V KT  N +CVLTM LNCTDC+  +S+P      CY ING  FNS+++ F + + D +I  YT Y I++ + N +GWGNL S   +T+QY SGPV   ++   +P   + I W  P   NG+IVQYFIWV++ N +CVLTMS+NCTDCK N+SVP  P+NS +NC   +G  FN   +  S+ I D KILP   Y +NIR LNGYGWGN +         +S P++NLSV  SFP  PL+I W PP     EI++Y IW+Q + NN+CVL   +NCTD  NN+S     + +   CY+I GL FNS +  FS+ I D  I P + Y +N+R L   GWG  S+ ++ T QY    + NL   S      + I W  P V
Sbjct:  274 GPVTNLSVTSLFPLSPLSITWAPPGVTNGEIVQYLIWVQKT--NNECVLTMSLNCTDCKNKISMPDNSTNACYTINGLNFNSNDKSFSMTINDGKILSYTNYTINIRSLNGYGWGNLSSKTIKTNQYISGPVTNVTVNSSFPSFPLSITWAPPGVTNGEIVQYFIWVQNTNNECVLTMSLNCTDCKNNLSVPRMPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYISGPVTNLSVTSSFPSFPLSIIWSPPVVSNGEIVQYFIWVQNT-NNECVLTMSLNCTDCKNNLSVPRIPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYTSGSIMNLSVASSFPSFPLSITWEPPGV 686          

Query:  471 VSNLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSV--PYLPD---YGCYQINGPT--FNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYP-HQIHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQ--SIVDKSQIKIVWSYPIV 1703
            V NL+ +S + ++ L I W+RP    G I+ Y V +     +  C+    L+C+DC+++       L D     C QIN  +   +++++   +   D  ++P T Y +   A N FGWG+  S+   T Q+ SGPV   S+T ++P   + I W  P   NG+IVQY IWV+  N +CVLTMS+NCTDCK  IS+   PDNS N C   +G  FN   +  S+ I D KIL    Y +NIR LNGYGWGN++      +  +S P++N++V  SFP  PL+I W PP     EI++Y IW+Q + NN+CVL   +NCTD  NN+S     + +   CY+I GL FNS +  FS+ I D  I P + Y +N+R L   GWG  S+ ++ T QY   PVTNL   S      + I+WS P+V
Sbjct:  140 VQNLNGTSKWGVNNLLIEWDRPSAIGGTILAYLVTIGGQLNDSVCIKRWLLSCSDCQESAQAIGQSLQDPSVRNCSQINNASSFVSTADKHLSLATNDSDVKPATSYLVIATALNEFGWGDAQSISLLTDQFISGPVTNLSVTSLFPLSPLSITWAPPGVTNGEIVQYLIWVQKTNNECVLTMSLNCTDCKNKISM---PDNSTNACYTINGLNFNSNDKSFSMTINDGKILSYTNYTINIRSLNGYGWGNLSSKTIKTNQYISGPVTNVTVNSSFPSFPLSITWAPPGVTNGEIVQYFIWVQNT-NNECVLTMSLNCTDCKNNLSVPRMPENSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINIRSLNGYGWGNSSSKTIQTDQYISGPVTNLSVTSSFPSFPLSIIWSPPVV 556          

Query: 2163 TGEGVPSSVLSFKCVNQSYTGIKCTWAPPVEKNGKILNYWLTCKNESVIYNDNITSTTVTISEWVETDILYTCQVSASTSVGYGAPVFSFLIIVPSAVPDMNNIDMIPDAMSKVNIKVADEYTQAAITLPYSHFSNNGGTIQMFTLVISETRNNIVGNASITSLQYQNVAYGECITKNTCVYEIRLSPPKPKRALKRNTNPKANWQNEEYIVG-NNLLGNKSDHNSNGPLKSGTLYIIGFRAYTSAGFVTVGFIERKTAVNKISTIVGVSVAVFVIICLS-----IAIYFIIRYKRNKHVSEATNTAITHLLPMDS-KSPAAHEFHENYEFMKQDSNGRLLDDFREIKELAVKLERQKVIMFTEGNDAKNRFSNIKPYKHNRVKLLAKNDYINASKICSAHWQSEKENE-CFCSNIYIATQGPIGENREPKAQTVGDFWRMILENNVCVIVNLTRVEEHGKEKCSQYWPTEINQKITYYSEDDPINVEMNSSMDYSIFVERVFNVSMDEKEISVTQLHMLAWKDHGCPTTSEFLAFYSAYRKARQSNQAIVVHCSAGVGRTGTFILIDEELSRILKEDDRIEIYNNLLNLRKCRCQMVQTESQYCFIYSVIHEYLVQAGLIRIPRDNR---EDSNLFRQSYENPIFVE 4073
            T + +   V +F C N S+  I C+W  P + NG IL+Y +TCK  SV++N  +T T + I+  ++ DILY  ++SASTS+G G  ++  + I PS  P + N   IPD +      V D   Q A+TLPY+HF+N+ G I+ FTLVIS   +    N++IT   Y ++                +  P+P   + R     + WQ+  +++G      N S +  NGPL S T YIIGFR YT+AGF T G I  +TA+N       + V  F+ + LS      A YF  RY+R              + P D+ KSP    FH ++EFMK+DSNGRL+D F++IK+   +LE Q V++F+ GN  KNR+ NIKPY+HNRVKL   +DYINAS+IC  HW ++     C C++ YIATQGP+GE+REPK  T+GDFWRM+LENNVC+IVNLTR EE+GKEKCSQYWP + N +I + S DD + V M +S + SIF ERV  VSM++ E +V QLHM +W DH CPTTS+F+ FY+AY +++  ++AI+VHCSAGVGRTG+FILIDEELSRI K  D++EIYN L NLRKCRCQMVQTESQYCFIY++IHE L+Q GL ++P  +R     S    QSY NPIF E
Sbjct:  122 TNQYISGPVSNFNCYNSSFNSIFCSWGFPSKANGVILSYTITCKASSVVFNKTLTDTWINITSSIKPDILYILEISASTSIGAGEKIYFNITISPSPFPFVINASKIPDVLRNSIATVNDSRYQLAVTLPYNHFNNDLGIIRKFTLVISTNDDIYPRNSTITKSSYSDL----------------ILLPEPGSQITRKKRAISEWQSRPFVIGATQSCSNSSSNTCNGPLLSATAYIIGFRVYTTAGFTTEGVITVRTAIN-----WAILVGFFIFLLLSGGIGFAAFYFYRRYRRLNRSDSDIVVIHGDICPDDNDKSPLTFNFHAHFEFMKRDSNGRLIDQFQDIKQQVKQLETQNVLVFSAGNIHKNRYGNIKPYQHNRVKLNKLDDYINASRICVRHWNTDLNGSPCNCTDYYIATQGPLGEDREPKVSTIGDFWRMVLENNVCIIVNLTRSEENGKEKCSQYWPDKNNDRIAFSSGDDLVEVIMTNSRENSIFTERVLTVSMNKYEKTVKQLHMTSWLDHSCPTTSDFMEFYAAYIRSKVPSEAIIVHCSAGVGRTGSFILIDEELSRIEKRTDKVEIYNTLFNLRKCRCQMVQTESQYCFIYTIIHECLIQRGLSKVPERDRPANPQSISHSQSYINPIFAE 748          

Query:  477 NLSTSSAFPLHPLNISWERPQTPNGEIVQYYVQVFKTPMNRQCVLTMFLNCTDCRKNVSVPYLPDYG---CYQINGPTFNSSNQRFGIIVKDERIRPYTYYGISVNAANVFGWGNLVSVYQETSQYTSGPVDIQSITGIYPHQIHIKWMNPTFENGQIVQYFI 956
            NLS +S+FP  PL+I+WE P   NGEIVQY + V  T  N +CVLT+  NCTDC+ N+SVP +PD     CY ING  FNS+N+ F + + D +I PYT Y I+V + N +GWGN  S   +T+QY SGPV   +      + I   W  P+  NG I+ Y I
Sbjct:    2 NLSVASSFPSFPLSITWEPPGVANGEIVQYLIWVQNT--NNECVLTVSFNCTDCKNNLSVPAMPDNSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINVRSLNGYGWGNSSSKTIQTNQYISGPVSNFNCYNSSFNSIFCSWGFPSKANGVILSYTI 162          

Query:  897 IHIKWMNPTFENGQIVQYFIWVEDVNGQCVLTMSVNCTDCKPNISVPPWPDNSINNCTAKSGGQFNVTKQLSSIVITDDKILPCITYRVNIRLLNGYGWGNVTGNYTSISPNVSEPISNLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSI 1346
            + I W  P   NG+IVQY IWV++ N +CVLT+S NCTDCK N+SVP  PDNS +NC   +G  FN   +  S+ I D KILP   Y +N+R LNGYGWGN +      +  +S P+SN +  ++     +   W  P      I+ Y+I
Sbjct:   14 LSITWEPPGVANGEIVQYLIWVQNTNNECVLTVSFNCTDCKNNLSVPAMPDNSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINVRSLNGYGWGNSSSKTIQTNQYISGPVSNFNC-YNSSFNSIFCSWGFPSKANGVILSYTI 162          

Query: 1251 NLSVIFSFPLAPLTIRWQPPKNKTMEIIKYSIWIQRSDNNQCVLKTEMNCTDVFNNVSQSSHMDTNITECYSIPGLKFNSTDDIFSLIIRDLAIQPKSKYVVNVRPLTMCGWGPISNISVTTPQYQPDPVTNLQSIVDK-SQIKIVWSYP-------IVHTINYKYDIQVYNGTFS 1754
            NLSV  SFP  PL+I W+PP     EI++Y IW+Q + NN+CVL    NCTD  NN+S  +  D +   CY+I GL FNS +  FS+ I D  I P + Y +NVR L   GWG  S+ ++ T QY   PV+N        + I   W +P       + +TI  K    V+N T +
Sbjct:    2 NLSVASSFPSFPLSITWEPPGVANGEIVQYLIWVQNT-NNECVLTVSFNCTDCKNNLSVPAMPDNSTDNCYTINGLNFNSNNKSFSMTINDGKILPYTNYTINVRSLNGYGWGNSSSKTIQTNQYISGPVSNFNCYNSSFNSIFCSWGFPSKANGVILSYTITCKASSVVFNKTLT 176