G domain-containing protein

Overview
NameG domain-containing protein
Smed IDSMED30034063
Length (bp)2027
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of G domain-containing protein (SMED30034063) t-SNE clustered cells

Violin plots show distribution of expression levels for G domain-containing protein (SMED30034063) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G domain-containing protein (SMED30034063) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G domain-containing protein (SMED30034063) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30034063

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30034063h1SMcG0007798 SmedASXL_015942SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30034063h1SMcG0007798 SmedASXL_015942SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30034063h1SMcG0007798 dd_Smed_v4_9367_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30034063h1SMcG0007798 dd_Smed_v4_9367_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30034063h1SMcG0007798 dd_Smed_v4_9367_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of G domain-containing protein vs. Ensembl Human
Match: NOA1 (nitric oxide associated 1 [Source:HGNC Symbol;Acc:HGNC:28473])

HSP 1 Score: 147.517 bits (371), Expect = 1.631e-36
Identity = 150/574 (26.13%), Postives = 252/574 (43.90%), Query Frame = 3 
Query:  399 GSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKNI----------DYYKKMLVEAAESRG-------------------IDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSP-TFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTR-------SQTFFELITYAHKDN-----EITSNSYDKEAMLNE--FATPKNYDQDKITTN-----KWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHAR--LTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEI-ETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            G  + ++  +  +C GCG+ ++C+    PGY+P E + +       L   +C RC+ L      L + V  + Y +++   L +    +V  + D+ DLP ++ L      +   +L++LGNK DLL Q               D  +  L+ A   +G                     ++ +  V LISAK    +E ++  +     Y+ + ++L+G+TN GKS+LFN LL+SD C       +  A +S  PGTTLN+LKFP+ N +P     R Q+ K      K  +   E     E +QL              +TF  L +   KDN     +  S ++D E   N+    T K+  Q ++T        W YDTPG+   + I + L +++V+ +    ++  P+ ++LK G+ L    + RID L+ ++  + T+ A   L   I + D  D  + ++   TL                  +P    E  +  P LV  D+ + E  G + + AD+ FSS GW+ ++        +R +TP       R P L+PY V  +G R
Sbjct:  128 GHPDPALPPSGVNCSGCGAELHCQDAGVPGYLPREKFLRTAEADGGLARTVCQRCWLLSHHRRALRLQVSREQYLELVSAALRRPGPSLVLYMVDLLDLPDAL-LPDLPALVGPKQLIVLGNKVDLLPQDAPGYRQRLRERLWEDCARAGLLLAPGHQGPQRPVKDEPQDGENPNPPNWSRTVVRDVRLISAKTGYGVEELISALQRSWRYRGD-VYLVGATNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTTLNLLKFPICNPTPYRMFKRHQRLK------KDSTQAEEDLSEQEQNQLNVLKKHGYVVGRVGRTF--LYSEEQKDNIPFEFDADSLAFDME---NDPVMGTHKSTKQVELTAQDVKDAHWFYDTPGITKENCILNLLTEKEVNIVLPTQSIV-PRTFVLKPGMVLFLGAIGRIDFLQGNQSAWFTVVASNILPVHITSLDRADALYQKHAGHTLLQ----------------IPMGGKERMAGFPPLVAEDIMLKEGLGASEAVADIKFSSAGWVSVTPNFKDRLHLRGYTPEGTVLTVR-PPLLPYIVNIKGQR 670
[Close]
BLAST of G domain-containing protein vs. Ensembl Celegans
Match: Y48E1B.2 (pep chromosome:WBcel235:II:13533486:13539996:-1 gene:WBGene00013001.1 transcript:Y48E1B.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y48E1B.2)

HSP 1 Score: 155.606 bits (392), Expect = 2.265e-39
Identity = 166/619 (26.82%), Postives = 283/619 (45.72%), Query Frame = 3 
Query:  228 SVEPVSIVASLASSEKLNNSDCTPTKMSNESEHDPKLVEFVNEYISADSELRKLLFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKN--IDYYKKMLVEAAESRGI-DQSKLELVDLISAKDCNRIEIVLDKI------LSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSP---------TFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYA----HKDNEITSNSYDKEAMLNEFATPKNYD-QDKI-TTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDK--HIYLT--IHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTV---PDYDAENSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH 1991
            +VE +S       +E L         +S++   +P ++  V+E I A S                     C GCG+  +C+    PG++P E+ EK   +   +   LC RC  L+     L+V+V    Y  + M +L K    +V L+ D++DLP SI   L+     +  ++++GNK DLL    +   +  +KK +  A E  G+ +   +    L+SAK    IE ++ +I      + +G   +  IFL+G TN GKS++FN LL+SDLCK  A   V  A  S  PGTT+++LKFP++   P           ++R    K +++   L + TG+    + ++ +  Q T   +  EL   A    H + E  +   +K+  L E    + Y  +D I    KW YDTPG VN +Q  S    E++  +     L  P   ++K G SL+   +AR+D+ +V +   + LT  ++ +L   ++ T + + ++ +         +  L P   +     +   P +  EN  +         ++ +G      D+V SSIGW+ ++   + T  + A+TPA  G   R+  ++PY+   RG R   SR + V 
Sbjct:  176 AVEHISFQRPGQRAEGLQEGSGKDQDLSDDLSSEPGMIGTVDEEIPASSR-------------------KCTGCGANFHCKDSSLPGFVPLEILEK--IDRRSVDQSLCKRCHLLQEHNFLLNVNVCDVDYTRM-MGELKKQPESLVVLVVDVTDLPGSIYPRLASVVGSRRPMIVVGNKVDLLPPDARTGYMWRFKKTVERAVEKAGLLENFHILHTALVSAKTGYGIEELITEIYLKYTNVKLGMRGD--IFLVGCTNAGKSTMFNALLQSDLCKVRAVDLVDRATTSIWPGTTISLLKFPVMKPGPYRLEMRRRRLMAHRAWAKKEMYARKLLLTETGDDRYAIPTALI--QNTYKASEEELQPMALRELHGEEEDEAEEDEKQRKLEER---RKYSLEDPIFARGKWCYDTPGTVNDNQCLSLFTLEELLNVTPRRVL-RPHTVLVKPGESLLIGGVARLDIEQVARAGQVLLTTFVNEQLPLNVMPTHECEDFYRK-----WLGTRALLVPQGQEAAGGRMTSWPGFRGENGEMGRRFEMRGRLKDEG---GCCDIVLSSIGWVMVTSERDVT--LSAFTPANKGITARIQPILPYSASLRGKRLPGSRFYKVQ 754
[Close]
BLAST of G domain-containing protein vs. Ensembl Celegans
Match: Y48E1B.2 (pep chromosome:WBcel235:II:13533486:13539362:-1 gene:WBGene00013001.1 transcript:Y48E1B.2b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y48E1B.2)

HSP 1 Score: 115.546 bits (288), Expect = 1.391e-27
Identity = 106/373 (28.42%), Postives = 174/373 (46.65%), Query Frame = 3 
Query:  957 IFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSP---------TFSNRRQKAKFLFSVGKLKSYTG-EKYPI--------LESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYD-QDKI-TTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDK--HIYLT--IHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIK----STVPDYDAENSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH 1991
            IFL+G TN GKS++FN LL+SDLCK  A   V  A  S  PGTT+++LKFP++   P           ++R    K +++   L + TG ++Y I         ++S+   QP       EL    H + E  +   +K+  L E    + Y  +D I    KW YDTPG VN +Q  S    E++  +     L  P   ++K G SL+   +AR+D+ +V +   + LT  ++ +L   ++ T + +      D +  +   + L  P          ++ P +  EN  +         ++ +G      D+V SSIGW+ ++   + T  + A+TPA  G   R+  ++PY+   RG R   SR + V 
Sbjct:    5 IFLVGCTNAGKSTMFNALLQSDLCKVRAVDLVDRATTSIWPGTTISLLKFPVMKPGPYRLEMRRRRLMAHRAWAKKEMYARKLLLTETGDDRYAIPTALIQNTYKASEEELQP---MALREL----HGEEEDEAEEDEKQRKLEER---RKYSLEDPIFARGKWCYDTPGTVNDNQCLSLFTLEELLNVTPRRVL-RPHTVLVKPGESLLIGGVARLDIEQVARAGQVLLTTFVNEQLPLNVMPTHECE------DFYRKWLGTRALLVPQGQEAAGGRMTSWPGFRGENGEMGRRFEMRGRLKDEG---GCCDIVLSSIGWVMVTSERDVT--LSAFTPANKGITARIQPILPYSASLRGKRLPGSRFYKVQ 355
[Close]
BLAST of G domain-containing protein vs. Ensembl Celegans
Match: Y48E1B.2 (pep chromosome:WBcel235:II:13533486:13541056:-1 gene:WBGene00013001.1 transcript:Y48E1B.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y48E1B.2)

HSP 1 Score: 115.546 bits (288), Expect = 1.391e-27
Identity = 106/373 (28.42%), Postives = 174/373 (46.65%), Query Frame = 3 
Query:  957 IFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSP---------TFSNRRQKAKFLFSVGKLKSYTG-EKYPI--------LESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYD-QDKI-TTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDK--HIYLT--IHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIK----STVPDYDAENSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH 1991
            IFL+G TN GKS++FN LL+SDLCK  A   V  A  S  PGTT+++LKFP++   P           ++R    K +++   L + TG ++Y I         ++S+   QP       EL    H + E  +   +K+  L E    + Y  +D I    KW YDTPG VN +Q  S    E++  +     L  P   ++K G SL+   +AR+D+ +V +   + LT  ++ +L   ++ T + +      D +  +   + L  P          ++ P +  EN  +         ++ +G      D+V SSIGW+ ++   + T  + A+TPA  G   R+  ++PY+   RG R   SR + V 
Sbjct:    5 IFLVGCTNAGKSTMFNALLQSDLCKVRAVDLVDRATTSIWPGTTISLLKFPVMKPGPYRLEMRRRRLMAHRAWAKKEMYARKLLLTETGDDRYAIPTALIQNTYKASEEELQP---MALREL----HGEEEDEAEEDEKQRKLEER---RKYSLEDPIFARGKWCYDTPGTVNDNQCLSLFTLEELLNVTPRRVL-RPHTVLVKPGESLLIGGVARLDIEQVARAGQVLLTTFVNEQLPLNVMPTHECE------DFYRKWLGTRALLVPQGQEAAGGRMTSWPGFRGENGEMGRRFEMRGRLKDEG---GCCDIVLSSIGWVMVTSERDVT--LSAFTPANKGITARIQPILPYSASLRGKRLPGSRFYKVQ 355
[Close]
BLAST of G domain-containing protein vs. Ensembl Fly
Match: CG10914 (gene:FBgn0034307 transcript:FBtr0086745)

HSP 1 Score: 196.823 bits (499), Expect = 3.576e-54
Identity = 171/540 (31.67%), Postives = 269/540 (49.81%), Query Frame = 3 
Query:  399 GSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIR--LVLLGNKSDLL-HQTNKNIDYYKKMLV-EAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLN--EFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVD---KHI-YLTIHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEI--ETKGFNVSS---ADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYS 1973
            G+ + S+ ++   C GCG+ ++C +   PGYIP E++ + +T  E L+ I C RC FL      LDV V    Y D I +  ++ K  +  +L D+ D P SI   +   N+L  +  + L+GNK DLL   +N  + + K  L  E  +  G +   ++ V LISAK    IE ++ ++     YK + ++L+G TN GKSSLFN LL SD C+  A   V+ A     PGTTL +L+FP+  L P  SN R   +F     +L S   EK  + +  +  A+ T S    + +    +  +   N +D  AM       T  N    +    +W+YDTPG++ PDQI+  L  E++ +L Q   +  P+ + L+  +S++   LAR+D+LE+    KH  +L +     +E +     D   AE+       +K+ +  P L  +     + +A     P L   D +I   ++G N  +    D+  SS GW+GI    +S C++RAWTP A G  +R P+LIP A +  G    YS
Sbjct:   96 GTPDPSLPASKVPCNGCGADLHCTNASLPGYIPSEIF-RDRTQQE-LQTITCKRCHFLNHYNIALDVVVAPSTYVDTISR--IQDKFALAIVLVDLLDFPCSIWPGMQ--NILGAKRPVFLVGNKVDLLPRDSNIYLQHIKDSLQREFIKHGGGNGLNIKNVSLISAKTGYGIEELITQLHKTWAYKGD-VYLVGCTNVGKSSLFNILLNSDYCRPEASDLVRKATTCPWPGTTLKLLRFPI--LRP--SNDRVYQRF----KRLVSERSEKAEMEKERRAVARETGSAAAAQPVAPVGRTFDRRENLHDAFAMAGGSRPITTLNDRGKEYKEARWVYDTPGVMQPDQISPLLTAEELVKL-QPATMIRPRAFRLRPQMSILLGGLARLDLLEITSPRKHFDWLKVFV-FASEHLPIMIADTQEAES------VYKRYVGSPFLG-VPFASENLEARLRRWPGLQCKDGDIVLASEGRNEETRLNCDITLSSAGWMGILLPGHSECRLRAWTPKAAGIYRREPALIPLADRLVGKHIRYS 611
[Close]
BLAST of G domain-containing protein vs. Ensembl Zebrafish
Match: noa1 (nitric oxide associated 1 [Source:ZFIN;Acc:ZDB-GENE-080220-18])

HSP 1 Score: 187.963 bits (476), Expect = 1.825e-50
Identity = 161/562 (28.65%), Postives = 263/562 (46.80%), Query Frame = 3 
Query:  336 LVEFVNEY--ISADSELRKLLFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKN-IDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRR----QKAKFLFSVGKLK---SYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEIT----SNSYDKEAMLNEFATPK---NYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHA--RLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            L++F +E   +    + R    +GS +     +  SC GCG+ ++C     PGY+P E Y K       L+  +C RCF ++     L  SV         +   ++  S +V L+ D+ DLP+SI  +L        R+V+LGNK DLL    +N +   ++ L+      GI     + V LISAK    IE ++  + + G ++ + ++LIG  N GKS+LFN LL+SD CK+ A   +  A +S  PGTTLN+LKFP++N +    +RR    Q+ +   +  +L+    Y+   Y I    +           F+L   AH  +E+     S S+  +   +   +PK       ++I    W YDTPG++  + + S L +++V  +     ++ P+ ++LK G  L    LARID L+     + T+ A  R+   I + D  D  + ++   TL                  VP    E   T P L+  D E++ +  + + AD+  SS GWI ++        +R   PAA G   R P L+P+ V+ +G R
Sbjct:  140 LIDFHDEGFPLHKPKKKRPQKVFGSPDAQAALSETSCSGCGALLHCTDPQEPGYLPSEKY-KPLLEGGGLERAVCQRCFLIQHQQRAL--SVRMSPDQYRAVVGSIRPLSALVLLILDLLDLPHSIIPDLPQLLGRNKRVVVLGNKVDLLPGDAQNYLQRVRRQLMADCARAGISADPRD-VHLISAKTGYGIETLISSLQTRGRHRGD-VYLIGMANAGKSTLFNTLLESDYCKSTAADAIHRATISPWPGTTLNLLKFPILNPTAHRLSRRAERLQQTQQNITADELRRITHYSRHGYLIGHVGRT----------FQL-KRAHSKDEVEFDADSLSFGGDLDGDVQKSPKADAELSYNEIKDAHWCYDTPGIIKENDLLSVLTEQEVKLVVPTVAIT-PRTFLLKPGTVLFLGGLARIDYLQGQNSCWFTVLASSRVPVHITSLDKADDIYQKHAGNTLLG----------------VPCGGEERMKTFPPLIAQDFELQGQDCDTAIADIKISSAGWIAVTADAGDQLLLRTRAPAAAGVCLRTPPLLPHIVRLKGQR 668
[Close]
BLAST of G domain-containing protein vs. Ensembl Xenopus
Match: NOA1 (nitric oxide associated 1 [Source:NCBI gene;Acc:100488516])

HSP 1 Score: 176.792 bits (447), Expect = 2.214e-47
Identity = 148/534 (27.72%), Postives = 242/534 (45.32%), Query Frame = 3 
Query:  438 CCGCGSTINCESIYNPGYIPYEVYE---KAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKN-IDYYKKMLVEAAESRGID-QSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLK---SYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTN---------------KWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHAR--LTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            C GCG+ ++      PGY+P E Y    K + + E++    C RC  L      L V V  + Y    + + ++ K G+V  + D+ D+P SI  +L         +++LGNK DLL   +   + Y K  L +     G++    +  V L+SAK    +E ++ K+     YK + ++L+G+TN GKS+LFN LL+SD CK  A   ++ A +S  PGTTL++LKFP+VN  P    +RQK        +LK   S T E     E  QL      S     +   + K  +++    + +A L  F+T  + +   ++ N                W YDTPG+V    + + L  ++V        +  P+ +IL  G++L    L RID L+ ++  + ++ A   L   I + D  D  + ++   TL                  VP    E     P L+P D++++  G + + AD+  S+ GWI ++        +R +TP       R P L+P  V  +G R
Sbjct:    7 CTGCGAVLHSLEPSLPGYLPSEKYASFLKCKDSNELM----CQRCCLLIYHQKALHVKVSQEEYRS--IVKSIQTKKGLVLFMVDMLDIPDSIFPDLIDIVGENKSILVLGNKVDLLPGDSPGYLKYLKGQLHDYCTKAGLNWMGNITDVHLLSAKTGYGVEELISKLQQSWKYKGD-VYLVGATNAGKSTLFNTLLQSDYCKEKASEIIKEATISPWPGTTLDLLKFPIVNPKPYRMFQRQK--------RLKEDFSKTEEDLSETELKQLKTLKKHSYVVGRVGRTSTKSQKMSKKDIEFDAELLSFSTEDDPEHGYLSENLREVNQFTYNELKDAHWFYDTPGIVKEGCVLNLLKDKEVKAALPTKAII-PRTFILSPGMTLFLAALGRIDFLQGERPAWFSVIASNLLPVHITSLDKADDIYTKHAGGTLLG----------------VPIGGEERMKEFPPLLPQDIKLKGIGASRAVADIKLSTAGWIAVTAHSGEQLHLRCFTPKGTSLTIRQPPLLPLVVNIKGER 508
[Close]
BLAST of G domain-containing protein vs. Ensembl Mouse
Match: Noa1 (nitric oxide associated 1 [Source:MGI Symbol;Acc:MGI:1914306])

HSP 1 Score: 149.443 bits (376), Expect = 3.261e-37
Identity = 142/566 (25.09%), Postives = 246/566 (43.46%), Query Frame = 3 
Query:  408 NKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIR-LVLLGNKSDLLHQTNKNI----------DYYKKMLVEAAESRGID--------------------QSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFEL---ITYAHKDNEITSNSYDKEAMLNEFATP------KNYDQDKITTN-----KWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHAR--LTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            + S+  +   C GCG+ ++C+    PGY+P E +  A          +C RC+ L      L + V  D Y +++   L   + G   +L  ++ L     L   L  L+  + L++LGNK DLL Q               D  +  LV A   +G                      ++ ++ V LISAK    +E ++  +     Y+ + ++L+G+TN GKS+LFN LL+SD C       +  A +S  PGTTLN+LKFP+ N +P    +RQ+ +      K +    E+    E SQL            +    +Y+ + +E+    +D +++  +  +       K+  Q ++T        W YDTPG+     I + L +++++ +   +++  P+ ++LK G+ L    +ARID L+ ++  + T+ A   L   I + D  D  + ++    L                  VP    E  +  P LV  D+ ++  G   + AD+ FSS GW+ ++     T  +R  TP         P ++PY V  +G R
Sbjct:  132 DASVPPSGIYCSGCGAELHCQHPGLPGYLPEEKFRDAAQAEGGPARTVCQRCWLLVHHGRALRLQVSRDQYLELVSAAL--RRPGPALVLYMVNLLDLPDALLPDLPKLVGPKQLIVLGNKVDLLPQDAPGYLKRLRKRLWDDCIRAGLVVAPGHQGPQYPAGDEPLEEIKNQNPSSRSRTVVKDVRLISAKTGYGVEEMISALQRSWRYRGD-VYLVGTTNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTTLNLLKFPICNPTPYRMFKRQR-RLQEDATKAEEDLSEE----EQSQLNQLKKHGYIVGRVGRTFSYSREQDEVPFE-FDADSLAFDMGSEPVVSVCKSTKQIELTPEDVKDAHWFYDTPGITKESCILNLLTEKEINTVLPTHSII-PRTFVLKPGMVLFLGGIARIDFLQGNQSAWFTVVASNFLPVHITSLDKADALYEKHAGHELL----------------LVPMGGKERMAQFPPLVAEDITLKGGGKFEAVADIKFSSAGWVAVTPYSEGTLHLRGHTPEGTALTVH-PPVLPYIVNVKGQR 670
[Close]
BLAST of G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q32LB9|NOA1_BOVIN (Nitric oxide-associated protein 1 OS=Bos taurus OX=9913 GN=NOA1 PE=2 SV=1)

HSP 1 Score: 157.147 bits (396), Expect = 4.639e-39
Identity = 151/576 (26.22%), Postives = 248/576 (43.06%), Query Frame = 3 
Query:  399 GSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNL-SLYNLLQIRLVLLGNKSDLLHQTNKNI---------------------DYYKKMLVEAAESRGIDQSK---------LELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKA--------------------KFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHAR--LTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEI-ETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            G  + ++  +  +C GCG+ ++C+    PGY+P E +  A      L+  +C RC+ L      L + V    + +++   L + +  +V  + D+ DLP ++  +L +L    Q  L++LGNK DLL Q   N                       Y +         RG + +          L  V LISAK    +E ++  +     Y+ + ++L+GSTN GKS+LFN LL+SD C       +  A +S  PGTTLN+LKFP+ N +P    +RQK                       L   G L    G  +   E     AQ  ++   F+  ++A         + DK     E  TP++     +    W YDTPG+   + I S L +++V+ +   +++  P+ ++LK G+ L    L RID L+ ++  + T+ A   L   I + D  D  + ++   TL                  VP    E  +  P LV  D+ + E  G + + AD+  SS GW+ ++     T  +R +TP       R P L+P+ V  +G R
Sbjct:  128 GHPDPTVPPSGQNCSGCGAELHCQDPGVPGYLPSEKFNSAVAEEGGLERTVCQRCWLLVHHRRALRLQVSQGQFLELVSAALRRPEPALVLYMVDLLDLPDTLLPHLPALVGPKQ--LIVLGNKVDLLPQDTPNYRQRLRERLWDECIGAGLLPPRGYRRAQRSSGDRPRGGEDNANLPSKSSTVLRDVRLISAKTGYGVEELISALQRSWRYRGD-VYLVGSTNAGKSTLFNTLLESDYCIAKGAEAIDRATISPWPGTTLNLLKFPICNPTPYRMFQRQKRLKRDATEAEEDLSQQEQNKLNLLKKHGYLVGRVGRTFSYSE-----AQKDKAAFEFDADSFAFDMGNEPVLAADKSTKRVEL-TPED-----VKDAHWFYDTPGITKENCILSLLTEKEVNIVLPTHSII-PRTFMLKPGMVLFLGALGRIDFLKGNQSAWFTVVASNFLPVHITSLDKADTMYQKHAGHTLLK----------------VPVGGEERMAGFPPLVAEDITLDEGLGESEAVADIKLSSAGWVAVTPQFKDTLTLRGYTPQGTVLTVRRP-LLPHIVNIKGKR 671
[Close]
BLAST of G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9JJG9|NOA1_MOUSE (Nitric oxide-associated protein 1 OS=Mus musculus OX=10090 GN=Noa1 PE=1 SV=1)

HSP 1 Score: 149.443 bits (376), Expect = 2.281e-36
Identity = 142/566 (25.09%), Postives = 246/566 (43.46%), Query Frame = 3 
Query:  408 NKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIR-LVLLGNKSDLLHQTNKNI----------DYYKKMLVEAAESRGID--------------------QSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFEL---ITYAHKDNEITSNSYDKEAMLNEFATP------KNYDQDKITTN-----KWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHAR--LTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            + S+  +   C GCG+ ++C+    PGY+P E +  A          +C RC+ L      L + V  D Y +++   L   + G   +L  ++ L     L   L  L+  + L++LGNK DLL Q               D  +  LV A   +G                      ++ ++ V LISAK    +E ++  +     Y+ + ++L+G+TN GKS+LFN LL+SD C       +  A +S  PGTTLN+LKFP+ N +P    +RQ+ +      K +    E+    E SQL            +    +Y+ + +E+    +D +++  +  +       K+  Q ++T        W YDTPG+     I + L +++++ +   +++  P+ ++LK G+ L    +ARID L+ ++  + T+ A   L   I + D  D  + ++    L                  VP    E  +  P LV  D+ ++  G   + AD+ FSS GW+ ++     T  +R  TP         P ++PY V  +G R
Sbjct:  132 DASVPPSGIYCSGCGAELHCQHPGLPGYLPEEKFRDAAQAEGGPARTVCQRCWLLVHHGRALRLQVSRDQYLELVSAAL--RRPGPALVLYMVNLLDLPDALLPDLPKLVGPKQLIVLGNKVDLLPQDAPGYLKRLRKRLWDDCIRAGLVVAPGHQGPQYPAGDEPLEEIKNQNPSSRSRTVVKDVRLISAKTGYGVEEMISALQRSWRYRGD-VYLVGTTNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTTLNLLKFPICNPTPYRMFKRQR-RLQEDATKAEEDLSEE----EQSQLNQLKKHGYIVGRVGRTFSYSREQDEVPFE-FDADSLAFDMGSEPVVSVCKSTKQIELTPEDVKDAHWFYDTPGITKESCILNLLTEKEINTVLPTHSII-PRTFVLKPGMVLFLGGIARIDFLQGNQSAWFTVVASNFLPVHITSLDKADALYEKHAGHELL----------------LVPMGGKERMAQFPPLVAEDITLKGGGKFEAVADIKFSSAGWVAVTPYSEGTLHLRGHTPEGTALTVH-PPVLPYIVNVKGQR 670
[Close]
BLAST of G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8NC60|NOA1_HUMAN (Nitric oxide-associated protein 1 OS=Homo sapiens OX=9606 GN=NOA1 PE=1 SV=2)

HSP 1 Score: 147.517 bits (371), Expect = 7.835e-36
Identity = 150/574 (26.13%), Postives = 252/574 (43.90%), Query Frame = 3 
Query:  399 GSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKNI----------DYYKKMLVEAAESRG-------------------IDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSP-TFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTR-------SQTFFELITYAHKDN-----EITSNSYDKEAMLNE--FATPKNYDQDKITTN-----KWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHAR--LTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEI-ETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            G  + ++  +  +C GCG+ ++C+    PGY+P E + +       L   +C RC+ L      L + V  + Y +++   L +    +V  + D+ DLP ++ L      +   +L++LGNK DLL Q               D  +  L+ A   +G                     ++ +  V LISAK    +E ++  +     Y+ + ++L+G+TN GKS+LFN LL+SD C       +  A +S  PGTTLN+LKFP+ N +P     R Q+ K      K  +   E     E +QL              +TF  L +   KDN     +  S ++D E   N+    T K+  Q ++T        W YDTPG+   + I + L +++V+ +    ++  P+ ++LK G+ L    + RID L+ ++  + T+ A   L   I + D  D  + ++   TL                  +P    E  +  P LV  D+ + E  G + + AD+ FSS GW+ ++        +R +TP       R P L+PY V  +G R
Sbjct:  128 GHPDPALPPSGVNCSGCGAELHCQDAGVPGYLPREKFLRTAEADGGLARTVCQRCWLLSHHRRALRLQVSREQYLELVSAALRRPGPSLVLYMVDLLDLPDAL-LPDLPALVGPKQLIVLGNKVDLLPQDAPGYRQRLRERLWEDCARAGLLLAPGHQGPQRPVKDEPQDGENPNPPNWSRTVVRDVRLISAKTGYGVEELISALQRSWRYRGD-VYLVGATNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTTLNLLKFPICNPTPYRMFKRHQRLK------KDSTQAEEDLSEQEQNQLNVLKKHGYVVGRVGRTF--LYSEEQKDNIPFEFDADSLAFDME---NDPVMGTHKSTKQVELTAQDVKDAHWFYDTPGITKENCILNLLTEKEVNIVLPTQSIV-PRTFVLKPGMVLFLGAIGRIDFLQGNQSAWFTVVASNILPVHITSLDRADALYQKHAGHTLLQ----------------IPMGGKERMAGFPPLVAEDIMLKEGLGASEAVADIKFSSAGWVSVTPNFKDRLHLRGYTPEGTVLTVR-PPLLPYIVNIKGQR 670
[Close]
BLAST of G domain-containing protein vs. UniProt/SwissProt
Match: sp|P54453|YQEH_BACSU (Uncharacterized protein YqeH OS=Bacillus subtilis (strain 168) OX=224308 GN=yqeH PE=1 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 6.969e-12
Identity = 77/256 (30.08%), Postives = 116/256 (45.31%), Query Frame = 3 
Query:  438 CCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLV------LLGNKSDLLHQTNKNIDYYKKMLVEAAESRGIDQSKLELVD--LISAKDCNRIEIVLDKILSIGFYKN-EPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLS-----PTFSNRRQKAKFL 1163
            C GCG TI  E     GY P     K        +N++C RCF L++  +  DVS+  D + +  +   +     +V  + DI D       N S  N LQ RLV      L+GNK+D+L ++ K     + M  EA E        L+ VD  L+SA     I  V+D   +I  Y+N + ++++G TN GKS+  NR++K                 S  PGTTL+ ++ P+ + S     P   N  Q A ++
Sbjct:    6 CIGCGVTIQTEDKTGLGYAPPASLTK--------ENVICQRCFRLKNYNEIQDVSLTDDDFLN--ILHGIGETDSLVVKIVDIFDF------NGSWINGLQ-RLVGGNPILLVGNKADILPKSLKRERLIQWMKREAKEL------GLKPVDVFLVSAGRGQGIREVID---AIEHYRNGKDVYVVGCTNVGKSTFINRIIKE------VSGEEDIITTSQFPGTTLDAIEIPLDDGSSLYDTPGIINNHQMAHYV 229

HSP 2 Score: 55.4546 bits (132), Expect = 8.495e-7
Identity = 47/172 (27.33%), Postives = 80/172 (46.51%), Query Frame = 3 
Query: 1389 LYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHARLTAEIVATDDIDRYFAEN-DHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAI 1901
            LYDTPG++N  Q+A Y+ K+D+  L  +  L +P+ + L +  +L F  LAR D +  ++  ++     +  E++    I R   EN D        + L+PP  D           E    P+LV     I+ K       D+VFS +GW+ +    ++  K+ A+ P  +
Sbjct:  213 LYDTPGIINNHQMAHYVNKKDLKILSPKKEL-KPRTFQLNDQQTLYFGGLARFDYVSGERSPFI---CYMPNELM----IHRTKLENADALYEKHAGELLTPPGKD-----------EMDEFPELVAHTFTIKDK-----KTDIVFSGLGWVTV---HDADKKVTAYAPKGV 357
[Close]
BLAST of G domain-containing protein vs. TrEMBL
Match: A0A564YXH7 (G domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS10315 PE=4 SV=1)

HSP 1 Score: 233.032 bits (593), Expect = 3.933e-63
Identity = 194/660 (29.39%), Postives = 305/660 (46.21%), Query Frame = 3 
Query:  276 LNNSDCTPTKMSNESEHDPKLVEFVNEYISADSELRKLLF--------YGSENKSIDSTPYSCC-GCGSTINCESIYNPGYIPYEVYEKAQTN--------PEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLH-QTNKNIDYYKKMLVEA-AESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGF--YKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKF--LFSVGKL-KSYTGEKYP-----------ILESSQLAAQPTRSQTFFELI----TYAHKDNEITSNSYDKEAM------------------LNEFATPKNYDQDKITTNKWLYDTPGL---------VNPDQIASYLP-----KEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDME-IETKGFNVSSADVVFSSIGWIGISGM-----------ENSTC--------KIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQF 1982
              +S   P   S++   DP    F       ++  RK L         Y   +KS  +  ++CC GCG+ I+C +    G++P     K +++        P     ILCV C  +      L  S+    Y  +++ +L   ++  + L+AD+++LP+S+ ++L L N    +++L+GNK D L     K    +  +L++A  ++ GID+S +  V LISA     I  +LD +LS  F  Y+N P++++GSTN GKSSLFNRLL SD CK+ A+ ++  A VS  PGTT  +LKFP+  ++      R +AK+  + S+ ++ K+   E Y             L SS ++ Q  R +  F+ +    TY  + +       ++  M                   +        D  +     W YDTPGL         +N DQ+A Y+      K D  +   E     P+ ++LK GLS++   L RIDVL     +YLT H RL   IV T+ +  Y++E   F        L P          P  D+   +IP + P D+E I+      S AD+V S  GW+ ++G+           E ++C         +RAWTP  +G   R PSL+PYA++RRG R  Y R+F
Sbjct:   57 FQSSQNVPKLASSQITVDPSTTNFKTPEPQRETSPRKQLIDHESLNRIYNLSDKSSATILHTCCAGCGAHIHCGTPGTHGFLPEPEVLKLKSHENSRRGRKPSNALPILCVHCQLVNQHKSALKQSLPSSEYGRLVISELNSQENATILLVADMTNLPHSL-VSLKLDNPSAHKIILIGNKVDQLPIDGPKYHSRWSDVLLKAFVKTSGIDESCVSHVALISALTGYGIHKLLDFLLSKRFNVYEN-PVYIVGSTNAGKSSLFNRLLLSDFCKSEARESIHRATVSYWPGTTAGLLKFPLSRMNFVKRALRDQAKYTEMHSLKRVAKAQHKELYGYLLLGEEETGLTLTSSNISDQADRVRNSFQDLSLQPTYRFRADGSGGEVIEESVMGLQSLIRKEIGVEAGLDSGDRLLVSGTIDPRQFNQKAWCYDTPGLESSEQTLNFLNGDQLAEYMALINGRKRDFHR--PEKRFILPRTFVLKPGLSMLLGRLGRIDVLGSKGPVYLTTHTRLPVHIVDTNQVTSYWSEYAIF--------LGP--------GAPYSDSH--SIPSMKPIDIEPIQPVDLEASVADIVLSGAGWVSVAGVREAMTGYEKMEETNSCPAGEDYGVNLRAWTPGGVGVSLRSPSLLPYAIRRRGERLLYLREF 694
[Close]
BLAST of G domain-containing protein vs. TrEMBL
Match: F4WM66 (Uncharacterized protein C4orf14-like protein OS=Acromyrmex echinatior OX=103372 GN=G5I_06899 PE=4 SV=1)

HSP 1 Score: 221.09 bits (562), Expect = 3.049e-60
Identity = 169/533 (31.71%), Postives = 273/533 (51.22%), Query Frame = 3 
Query:  396 YGSE--NKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSI--PLNLSLYNLLQIRLVLLGNKSDLLHQTNKNI-DYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAML---NEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHA--RLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            YG+   N SI S P  C GCG+ ++C+    PGY+P E++ K ++N E L+ ++C RC F+      L+V V  D Y    + ++++ K   V L+ D++D P SI   +N  L+ L  + +V  GNK DLL Q +K    + K  L++A ES  I +  +  ++LISAK    IE +++K+ +I  YK + +++IG TN GKSSLFN LL+SD CK  A   +Q A +S  PGTTLN+LKFP++N         ++ +      +LK     K+   +S     + TR+  +  L ++  +  + + N    E       +F   +N ++ K++  +W YDTPG + P QI   L  +++  +  +  +S P+ +IL    ++    + R+D +E +  I  TI +   L   +  T+D D  + E                LL      VP+ + +     P LV  +MEI   G N S +D+V SS GWI I+  ++    ++AW P   G   R P+L+  +V  RGTR
Sbjct:   20 YGTPDPNSSISSIP--CGGCGALLHCKDPALPGYLPSELFLK-RSNRE-LRVMICQRCHFMHYYNTTLEVKVSADEYPK--LLKVIRTKKCAVILMVDLTDFPCSIWPEINSVLHPLTPVFVV--GNKVDLLPQDSKYFFTHIKDCLLKAMESTKIKKENIRHIELISAKTGYGIEELINKLHNIWKYKGD-VYIIGCTNVGKSSLFNALLQSDYCKVQAVDLIQRATISPWPGTTLNLLKFPILN--------PKRKRLYLRALRLKMEQRHKHAEEKSRIGQFEMTRNLKYATLQSHIGRTFQSSKNDLFMEGKFKKNTQFGFDENREEFKLS--RWCYDTPGTIQPAQILDLLTTQELLSVLPKKIIS-PRTFILHVNQTIFLGGIGRLDYVEGNTFIRCTIFSSNELPITLTHTEDADNVYDE----------------LLKTEAFVVPENNPDRLKHWPPLVSKEMEITGVGQNESISDIVLSSAGWIAIAAEKDERVLLKAWNPQGRGLHLRTPALLKKSVTLRGTR 516
[Close]
BLAST of G domain-containing protein vs. TrEMBL
Match: E9G1E1 (CP-type G domain-containing protein OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_313052 PE=4 SV=1)

HSP 1 Score: 224.942 bits (572), Expect = 3.261e-60
Identity = 173/559 (30.95%), Postives = 278/559 (49.73%), Query Frame = 3 
Query:  390 LFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKN-IDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFA-------------TPKNYDQDKITTNKWLYDTPGLVNPDQIASY---------LPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHAR--LTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN--STIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFH 1985
            L YG+ N  I  +   C GCG+ ++C+S   PGY+P E++   QT+   L+  +C RC FLR     L+V++  + Y  +I   +++ +  +V L+ D+ D P SI   L      +  + ++GNK DL+ + ++  +++ +K LV   E+ GI+++ ++LV LISA     +E ++ KI +    + + ++L+G TN GKSSLFN L+ SD CKT A   ++ A VS  PGTTLN+LKFPM+  S   S R  +         L   T E+   +   QL  + TR++ F  LI   H     T+ + ++    + F+              PK+ D      +KW +DTPG +NP QI +          LPK+          L +P+  ++K G++     L RID ++    + LT  A   L   ++   D D+ +AE            L  P+L      VP + +E      P L   D+ +   G+  S+ D+V SS GW+ ++G E +  K++A+TP   G   R P L+P AV  RGTR + S+ F 
Sbjct:  191 LNYGTPNPDIPVSIIPCGGCGAKLHCQSPSIPGYLPSEIFSSFQTHD--LRGQICQRCRFLRDHDVALNVNISPEEYPKVI--SVIRDQVAMVILVVDLLDFPCSIWPGLLDIIGTKRPVCVVGNKVDLIPKDSRGYLNHIQKCLVNELENSGINRANIKLVSLISATTGFGVEQLITKIQNSWGARGD-VYLLGCTNVGKSSLFNALISSDFCKTQASDLLERATVSAWPGTTLNLLKFPMLRPS---SIRLYERTLRLKAESLSHATEER---MRKEQL--KETRNREFATLI--GHIGRTFTAKTKEEREAFDPFSLRAVIPGDEKRSFNPKSKD---FLDSKWCFDTPGTINPSQILTLLTLEELMRTLPKK----------LIKPRTVLIKPGMTYFLAGLGRIDYVDGPHSLLLTTLASSDLPLTLIDHQDADQMYAE-----------LLGSPIL-----AVP-FGSEKRLKHWPGLSGKDITVTGVGWKESAVDIVLSSAGWVAVTGEEGTKYKLKAYTPYGRGIHVRTPPLLPRAVMLRGTRLSSSQGFR 704
[Close]
BLAST of G domain-containing protein vs. TrEMBL
Match: A0A0K8T9Y4 (G domain-containing protein OS=Lygus hesperus OX=30085 PE=4 SV=1)

HSP 1 Score: 224.557 bits (571), Expect = 4.177e-60
Identity = 173/552 (31.34%), Postives = 268/552 (48.55%), Query Frame = 3 
Query:  351 NEYISADSELRKLLFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKN-IDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPK--------NYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVD-KHIYLTIHA--RLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEIETKGFNVSS----ADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRG 1955
            +E   ADSE   +L YG+ N++I S+   C GCG+ ++C+    PG+IP E++ + +T  + L+ I C RC+FL++    L ++VD  +Y    +   +K K  ++ L  D++D P SI   +S    L   + L+GNK DLL   +K  +D  +K L     S+    +K+    LISAK    +E ++ K+  I  Y+ + ++L+G TN GKS+LFN LL+SD CK  A   VQ A  S  PGTTLN+LKFP++        R +  +      +LK+ +      L   Q     ++  +  +LI +  +    +S + D      +F+ PK        N +       +W YDTPG+++ DQI   L  E++ ++  +  + EP+  I+K G +L    LAR+D L+ + K I  T+     L   I  T+D    +                  LL+  K  VP  DA+     P L   D   E K   VS      DVV SS GW+  +  E    +IR WTP   G   R P+L+P+ V  RG
Sbjct:  178 DEEQRADSEW--VLKYGTSNRAIPSSHIPCGGCGALLHCKDTSIPGFIPQELFRECKT--QDLRTITCQRCYFLQNHNTALSIAVDAKVYPK--IISYVKRKKALLLLAVDLTDFPCSIWPGISDLVGLDCPMFLVGNKVDLLCGDSKGWMDRVEKSLRSCFPSK----AKILGTQLISAKTGFGVEELITKLQKIWQYQGD-VYLVGCTNVGKSTLFNALLQSDYCKVKAADLVQRATTSPWPGTTLNLLKFPIM--------RPEGWRTYLRSQRLKTESNRAELHLRHEQARDDKSKRDSPIQLIGHIGRTFHQSSKNEDDPFSSPDFSNPKTPIPGGGLNPNDPDFVKGRWFYDTPGVLHDDQILDLLTTEELVKVLHQKTI-EPRTVIMKPGWTLFVGGLARVDYLQGESKSIRWTVFVSRELPITICFTEDAQEVYET----------------LLESDKFVVPHSDAQRLKKWPSLKFKD---EYKFSGVSRYQCCGDVVLSSCGWVSFAANEKEIIRIRPWTPEGRGIYTRFPALLPFTVNNRG 690
[Close]
BLAST of G domain-containing protein vs. TrEMBL
Match: A0A151IGH9 (Uncharacterized protein C4orf14 OS=Cyphomyrmex costatus OX=456900 GN=ALC62_08942 PE=4 SV=1)

HSP 1 Score: 225.328 bits (573), Expect = 4.451e-60
Identity = 176/559 (31.48%), Postives = 274/559 (49.02%), Query Frame = 3 
Query:  339 VEFVNEYISADSELRKLLFYGSE--NKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSI--PLNLSLYNLLQIRLVLLGNKSDLLHQTNKNI-DYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVN----------LSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHA--RLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAEN-STIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            VE  N+ +  D+ L     YG+   N +I S P  C GCG+ ++C+    PGY+P E++ K       L+ ++C RC F++     L+V V  D Y    + +++K K   V L+ D++D P SI   +N  L+   Q+ +V  GNK DLL Q +K    + K  L++A E+ GI +  ++ V L+SAK    IE +++K+ ++  YK + ++LIG TN GKSSLFN LLKSD CK  A   +Q A +S  PGTTLN+LKFP+++          L      + ++A+  F + + K     KY  L+S      P+ S           K++ +    + K        T   Y Q     ++W YDTPG + PDQI   L  +++  +  +  +S P+ +IL    ++    + R+D ++ D +I  TI +   L   +  T+D D  + E                LL      VP+ + +     P L+   MEI   G N S AD+V SS GWI I+  E     ++AW P   G   R P+L+  +V  RG R
Sbjct:  226 VEQYNDTLQDDNWLNN---YGTPDPNSNISSVP--CGGCGALLHCKDQALPGYMPSELFLKRSKKE--LRVMICQRCHFMQYYNTTLEVKVSADEYPK--LLKVIKTKKCAVILMVDLTDFPCSIWPEINSVLHPYTQVFVV--GNKVDLLPQDSKKFFTHIKDCLLKAVENTGIKKENIKHVALVSAKTGYGIEELINKLQNLWKYKGD-VYLIGCTNVGKSSLFNALLKSDYCKIQAVDLIQRATISPWPGTTLNLLKFPILSPRKWRLYLRTLRLKMEQKHKQAEETFRINQFKITHNLKYATLQSHIGRTFPSTS-----------KNDLLMVEKFKKNTQFGFDDTKHEYKQ-----SRWCYDTPGTIQPDQILDLLTMQELLSVLPKKIIS-PRTFILHVNQTIFLGGIGRLDYIKGDNYIRCTIFSSNELPITLTHTEDADNVYNE----------------LLQTEAFVVPENNPDRLKYWPPLISKKMEITGIGRNESVADIVLSSAGWIAIAAEEADRVLLKAWNPQGRGLYLRTPALLKKSVTLRGKR 739
[Close]
BLAST of G domain-containing protein vs. Ensembl Cavefish
Match: noa1 (nitric oxide associated 1 [Source:NCBI gene;Acc:103034327])

HSP 1 Score: 185.652 bits (470), Expect = 1.538e-49
Identity = 154/539 (28.57%), Postives = 262/539 (48.61%), Query Frame = 3 
Query:  396 YGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKN-IDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYP-ILESSQLAAQPTRSQTFFELITYAHKDNEITSN--SYDKEAMLNEFATPKNYDQDKITTN---------KWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHA--RLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPL--LDRIKSTVPDYDAENSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            YG+ +  +  +   C GCG+ ++C     PGY+P E + K     + LK  +C RCF L      L+V++  + Y  I+ K  +K +  +V L+ D+ DLP SI  +L         +V+LGNK DLL     N +   +  L +     G+  +  + + LISAK    IE ++ ++     YK + ++L+G+ N GKS+LFN LL+SD CK+ A   +  A +S  PGTTLN+LKFP++N +P    RR +   L +    +  + E+   I + S+      R    F +     K  E   +  S+ ++   +    P+  D D + T           W YDTPG++    + S L +++V ++    +   P+ ++LK G+ L    LARID LE ++  + T+ A  ++   I + D  D  + ++   +L      L+ P+   +R+K   P ++A+          D E+E +G   +  D+  SS GW+ ++  +    ++RA  P A G   R P L+P+ V  +G R
Sbjct:  206 YGTPDAEVPVSDSCCTGCGALMHCTIPEVPGYLPSEKF-KQLIEEDSLKQAVCQRCFLLVHHQKALNVTMSKEEYRKIVGK--IKSQKALVLLIVDLLDLPDSIVPDLPQLVGQNKHVVILGNKVDLLPGDADNYLKRIRGQLAQYCADAGVAITDQKDIHLISAKTGYGIENLITRLQMSWKYKGD-VYLVGTANAGKSTLFNTLLESDYCKSRASDVIHKATISPWPGTTLNLLKFPIINPTPYRLFRRAERLRLAAQETEEDLSPEELKRIRQFSRQGYLVGRVGRTFRVDQSKKKLVEFDPDSLSFGEDLTEDSVGKPRE-DTDTVETELPYNEIKDAHWFYDTPGIMKEYDVLSVLNEQEV-KIVSPTHAITPRTFLLKPGMVLFLGALARIDYLEGNQSCWFTVVASSQIPVHITSLDKADAVYDKHAGNSL------LAVPMGGKERMKE-FPPFEAQ----------DFELEGQGVKTAVTDIKLSSAGWVSVTAAQGERLRLRAHAPKAAGLCLRTPPLLPHIVNVKGDR 721
[Close]
BLAST of G domain-containing protein vs. Ensembl Nematostella
Match: EDO37137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGR2])

HSP 1 Score: 166.007 bits (419), Expect = 1.814e-44
Identity = 142/531 (26.74%), Postives = 250/531 (47.08%), Query Frame = 3 
Query:  438 CCGCGSTINCESIYNPGYIPYEVY-EKAQTNPEILKNILCVRCFFLR--SDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQI-----RLVLLGNKSDLLHQTNKNIDYYKKM---LVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSN--VQSAVVSNLPGTTLNILKFPMVN-LSPTFSNRRQKAKFL---FSVGKLKSYTGEKY--PILESSQLAAQPTRSQTFFELITY----AHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHA--RLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRG 1955
            C GCGS      I +PGYI  E + EK ++       ++C RCF LR  S   P  V+          + +    +  ++  + DI DLP S     +  +LL I     R+V++ NK D+L Q  +     K++   ++      G++   ++ V L+SAK+   +  ++ KIL + +  +  I+++G +N GK++LFN  +  DL     +    +Q + VS  PGTT+++++FP+ + +      R +  KF    F + K    +   Y  P L      A    ++ FF    +    +H   E    S  + + L+ F  P+  D+       W YDTPG+++ +QI SYL  +++ +L   N    P+  IL+ G +L+   L R+D L+ +K IY T+ A   L   ++ T   D +  +      +     L  P  D         +   +  P L+P ++ +   G+  S+ADVV S+ GW+ ++    +   ++A+TP   G G R+P+L+P +V +RG
Sbjct:    1 CPGCGSIFQSNDIESPGYIRAEKHPEKQRSYYANESQVICQRCFDLRYYSKAIPTLVNTAQVTKFLSHISR----RKALILYVVDILDLPGS-----TFPHLLDIVGPAKRIVIVANKVDMLPQDGRPWLQEKRLREEVLRLCREHGLESGNVKDVCLVSAKEGFGVPQLVQKIL-VHWDHDGDIYMLGCSNSGKTTLFNTFM--DLLNVHKRRGNMLQRSTVSKWPGTTMSLMRFPLGHWMLHKLLYRLRHQKFFKQDFQLQKDTHNSPMHYYLPCLLQHSFTAL---AKKFFSKAKHVDRKSHDTTEGAIASVSQSSELDAF-KPELVDRKAKQRQLWFYDTPGIISENQITSYLTLKEI-KLLSPNRWMVPRTLILRPGQTLLLGGLGRLDFLKANKSIYFTVFASPNLPVHVLNTLKADNFLQQ------HGGSNILKVPCGD---------EKRMALFPPLLPHELSLVGAGWGESAADVVLSNAGWVAVTAGMGADVSLKAYTPNGRGVGVRIPALLPTSVTQRG 499
[Close]
BLAST of G domain-containing protein vs. Ensembl Medaka
Match: noa1 (nitric oxide associated 1 [Source:NCBI gene;Acc:101163064])

HSP 1 Score: 189.119 bits (479), Expect = 7.042e-51
Identity = 151/526 (28.71%), Postives = 253/526 (48.10%), Query Frame = 3 
Query:  435 SCC-GCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKN-IDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQK-----------AKFLFSVGKLKSYTGEKYPILESSQL--AAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHAR--LTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTR 1961
            +CC GCG+ ++C +   PGY+P E Y KA      L   +C RC  L      L++ +  + Y +  + Q ++    +V L+ D+ DLP SI  +L         +V+LGNK DLL   + N +   K+ L    +  G   S++  + LISAK    +E ++  +     YK + ++L+GS N GKS+LFN LL+SD CK+ A   +  A +S  PGTTLN+LKFP++N +P    RRQK                 + +L+  + + Y +    +   +  P R +  F+  + A  ++E  +     E  +++     +Y++  +    WLYDTPG++    I   L +++V QL        P+ ++L+ G+SL    L RID L+ +K  + +I A   +   + + D  D  + ++    L       S    +R+K+            P LV  D  +E  G+  ++ DV  SS GW+ ++ +E    ++R   P   G G R P L+P+ V  +G R
Sbjct:  169 TCCSGCGALMHCTAADVPGYLPSEKY-KALLMDGQLGGAICQRCHLLTHHHKALNLQLTREQYRE--VVQQIRPHRALVLLIVDLLDLPDSIVPDLPGLVGANKHIVVLGNKIDLLPGDSPNYLQRLKRQLSGYCQQAGFG-SQVTDIHLISAKTGYGVEALISSLQRSWKYKGD-VYLVGSANAGKSTLFNTLLESDYCKSRASDVIHKATISPWPGTTLNLLKFPIINPTPYRMFRRQKRLKEAEQQMENELTPLELKRLQHLSRQGYLVGRVGRTFRSDGPKRDEIEFDPDSLAFGEDEEPA-----ETTVHQSHDELSYNE--LKDAHWLYDTPGIIKEHDILQLLQEKEV-QLVVPTRAVVPRTFVLQPGMSLFVGALFRIDFLQGEKSCWFSIMASNLVPVHVTSLDKADSIYEKHAGHVLLGVPTGGS----ERMKA-----------FPALVHQDFSVEGGGYLEAAVDVKLSSAGWVAVTAVEGQQLQLRVHGPPGAGLGLRTPPLLPHVVNLKGER 666
[Close]
BLAST of G domain-containing protein vs. Planmine SMEST
Match: SMESG000074496.1 (SMESG000074496.1)

HSP 1 Score: 1263.06 bits (3267), Expect = 0.000e+0
Identity = 630/634 (99.37%), Postives = 630/634 (99.37%), Query Frame = 3 
Query:   90 MKKATILLNIFKTPSLFSKRFYRGKYLTDYQKRVSVLEKKVNVNNISVEPVSIVASLASSEKLNNSDCTPTKMSNESEHDPKLVEFVNEYISADSELRKLLFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKNIDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH 1991
            MKKA ILLN FKTPSLFSKRFYRGKYLTDYQKRVSVLEKKVNVNNISVEPVSIVASLASSEKLNNSDCTPTKMSNESEHDPKLVEFVNEYISADSELRKLLFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVDYDIYDDIIMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNL QIRLVLLGNKSDLLHQTNKNIDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEIETKGF VSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH
Sbjct:    1 MKKAMILLNSFKTPSLFSKRFYRGKYLTDYQKRVSVLEKKVNVNNISVEPVSIVASLASSEKLNNSDCTPTKMSNESEHDPKLVEFVNEYISADSELRKLLFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVDYDIYDDIIMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLPQIRLVLLGNKSDLLHQTNKNIDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEIETKGFYVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH 634
[Close]
BLAST of G domain-containing protein vs. Planmine SMEST
Match: SMESG000074496.1 (SMESG000074496.1)

HSP 1 Score: 1254.2 bits (3244), Expect = 0.000e+0
Identity = 626/629 (99.52%), Postives = 626/629 (99.52%), Query Frame = 3 
Query:  105 ILLNIFKTPSLFSKRFYRGKYLTDYQKRVSVLEKKVNVNNISVEPVSIVASLASSEKLNNSDCTPTKMSNESEHDPKLVEFVNEYISADSELRKLLFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVXXXXXXXXXMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKNIDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH 1991
            ILLN FKTPSLFSKRFYRGKYLTDYQKRVSVLEKKVNVNNISVEPVSIVASLASSEKLNNSDCTPTKMSNESEHDPKLVEFVNEYISADSELRKLLFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVDYDIYDDIIMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNL QIRLVLLGNKSDLLHQTNKNIDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEIETKGF VSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH
Sbjct:    2 ILLNSFKTPSLFSKRFYRGKYLTDYQKRVSVLEKKVNVNNISVEPVSIVASLASSEKLNNSDCTPTKMSNESEHDPKLVEFVNEYISADSELRKLLFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEILKNILCVRCFFLRSDLDPLDVSVDYDIYDDIIMKQLLKYKSGVVFLLADISDLPYSIPLNLSLYNLPQIRLVLLGNKSDLLHQTNKNIDYYKKMLVEAAESRGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGKSSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSNRRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKDNEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYLPKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIHARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAENSTIPDLVPSDMEIETKGFYVSSADVVFSSIGWIGISGMENSTCKIRAWTPAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH 630
The following BLAST results are available for this feature:
BLAST of G domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
NOA11.631e-3626.13nitric oxide associated 1 [Source:HGNC Symbol;Acc:... [more]
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BLAST of G domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Y48E1B.22.265e-3926.82pep chromosome:WBcel235:II:13533486:13539996:-1 ge... [more]
Y48E1B.21.391e-2728.42pep chromosome:WBcel235:II:13533486:13539362:-1 ge... [more]
Y48E1B.21.391e-2728.42pep chromosome:WBcel235:II:13533486:13541056:-1 ge... [more]
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BLAST of G domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG109143.576e-5431.67gene:FBgn0034307 transcript:FBtr0086745[more]
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BLAST of G domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
noa11.825e-5028.65nitric oxide associated 1 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of G domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
NOA12.214e-4727.72nitric oxide associated 1 [Source:NCBI gene;Acc:10... [more]
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BLAST of G domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Noa13.261e-3725.09nitric oxide associated 1 [Source:MGI Symbol;Acc:M... [more]
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BLAST of G domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q32LB9|NOA1_BOVIN4.639e-3926.22Nitric oxide-associated protein 1 OS=Bos taurus OX... [more]
sp|Q9JJG9|NOA1_MOUSE2.281e-3625.09Nitric oxide-associated protein 1 OS=Mus musculus ... [more]
sp|Q8NC60|NOA1_HUMAN7.835e-3626.13Nitric oxide-associated protein 1 OS=Homo sapiens ... [more]
sp|P54453|YQEH_BACSU6.969e-1230.08Uncharacterized protein YqeH OS=Bacillus subtilis ... [more]
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BLAST of G domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A564YXH73.933e-6329.39G domain-containing protein OS=Hymenolepis diminut... [more]
F4WM663.049e-6031.71Uncharacterized protein C4orf14-like protein OS=Ac... [more]
E9G1E13.261e-6030.95CP-type G domain-containing protein OS=Daphnia pul... [more]
A0A0K8T9Y44.177e-6031.34G domain-containing protein OS=Lygus hesperus OX=3... [more]
A0A151IGH94.451e-6031.48Uncharacterized protein C4orf14 OS=Cyphomyrmex cos... [more]
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BLAST of G domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
noa11.538e-4928.57nitric oxide associated 1 [Source:NCBI gene;Acc:10... [more]
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BLAST of G domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO371371.814e-4426.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of G domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
noa17.042e-5128.71nitric oxide associated 1 [Source:NCBI gene;Acc:10... [more]
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BLAST of G domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000074496.10.000e+099.37SMESG000074496.1[more]
SMESG000074496.10.000e+099.52SMESG000074496.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034063 ID=SMED30034063|Name=G domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2027bp
GTTCTAAGTTAAATTTTTATTTTTGATGAAAATTGTGACAAATTGATATA
CATTTATTTTTAATTTAAAATTCACATTATTTCAGTGTAATGAAGAAAGC
TACGATTCTTTTAAATATTTTTAAAACACCCTCATTATTTTCTAAAAGGT
TTTATCGTGGGAAATATTTGACGGACTATCAAAAACGGGTCTCTGTTTTA
GAAAAAAAAGTTAACGTTAATAATATTTCAGTCGAACCAGTTAGCATAGT
TGCCAGCTTAGCATCCAGTGAAAAATTAAATAATAGTGATTGTACTCCAA
CAAAAATGTCGAATGAATCTGAACATGATCCAAAGTTGGTAGAATTTGTT
AATGAATATATTTCTGCGGATAGCGAACTTCGAAAATTATTATTCTACGG
ATCAGAAAATAAAAGTATTGATTCAACTCCATATAGTTGTTGCGGGTGTG
GTAGTACAATTAATTGCGAATCTATATACAACCCAGGGTATATCCCTTAT
GAAGTTTATGAAAAAGCTCAAACTAATCCAGAAATATTGAAAAATATTCT
TTGTGTTAGATGTTTCTTTTTACGTAGTGATTTGGATCCATTGGATGTTT
CTGTTGATTACGATATTTATGATGATATAATAATGAAACAACTACTTAAA
TACAAATCAGGAGTAGTATTCTTATTGGCAGATATTTCAGATTTGCCATA
TAGTATTCCCTTGAATTTGTCTCTGTATAATTTACTTCAAATTCGACTCG
TTTTGTTAGGAAACAAATCTGATTTATTACATCAAACGAATAAAAATATT
GATTATTATAAAAAAATGTTGGTTGAAGCTGCGGAATCCAGAGGAATTGA
TCAATCCAAATTAGAATTAGTCGATCTTATTAGTGCAAAAGATTGCAATC
GAATAGAAATCGTGTTGGATAAGATTCTTAGCATTGGTTTCTACAAAAAC
GAACCGATATTCCTAATTGGATCAACGAATTGTGGCAAATCATCTCTTTT
TAATCGATTATTAAAATCCGATTTGTGTAAAACGATTGCCAAATCAAATG
TACAATCTGCCGTTGTTTCCAATTTACCTGGTACCACATTAAATATTTTA
AAGTTTCCTATGGTCAATTTGTCACCAACGTTTTCCAATCGTCGCCAAAA
AGCTAAATTTCTTTTTTCAGTCGGAAAATTGAAATCATATACTGGTGAAA
AATATCCTATTTTAGAAAGCTCCCAGCTTGCGGCCCAACCAACGCGTTCA
CAAACATTTTTTGAATTAATCACATATGCACACAAAGACAACGAAATCAC
TTCTAACTCCTACGATAAAGAAGCAATGTTAAATGAGTTTGCAACCCCAA
AAAACTACGATCAAGATAAAATTACAACAAATAAATGGCTCTATGACACA
CCTGGGCTCGTGAATCCAGATCAGATTGCGTCATATCTCCCAAAAGAAGA
TGTTGATCAATTATATCAAGAAAATAATCTCAGTGAACCGAAAATATATA
TTTTAAAAGAAGGTCTTAGCCTTATATTTCAAAATCTTGCTCGAATCGAT
GTTCTCGAAGTGGATAAACATATTTATTTGACCATTCATGCTCGACTTAC
TGCTGAAATTGTCGCCACTGATGACATAGATAGATATTTTGCGGAAAATG
ATCATTTTACCTTGTATTCATTTAAGAAGACTCTTTCACCGCCACTATTA
GATAGGATTAAGTCCACTGTTCCTGATTACGACGCTGAAAATTCTACGAT
TCCAGATTTAGTGCCGTCAGATATGGAGATTGAAACTAAAGGATTTAATG
TATCATCTGCTGATGTGGTTTTTTCGTCAATTGGTTGGATTGGAATCAGT
GGGATGGAAAATTCTACTTGTAAAATCAGAGCTTGGACCCCAGCAGCAAT
TGGATGTGGTAAAAGAGTCCCATCGCTAATACCATATGCAGTTAAAAGGC
GCGGTACTAGGAAGGCTTATTCCAGGCAATTCCATGTACACTAGAATAAT
ACATTTTTGATCTTTGTTTTGAGGACA
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protein sequence of SMED30034063-orf-1

>SMED30034063-orf-1 ID=SMED30034063-orf-1|Name=SMED30034063-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=635bp
MKKATILLNIFKTPSLFSKRFYRGKYLTDYQKRVSVLEKKVNVNNISVEP
VSIVASLASSEKLNNSDCTPTKMSNESEHDPKLVEFVNEYISADSELRKL
LFYGSENKSIDSTPYSCCGCGSTINCESIYNPGYIPYEVYEKAQTNPEIL
KNILCVRCFFLRSDLDPLDVSVDYDIYDDIIMKQLLKYKSGVVFLLADIS
DLPYSIPLNLSLYNLLQIRLVLLGNKSDLLHQTNKNIDYYKKMLVEAAES
RGIDQSKLELVDLISAKDCNRIEIVLDKILSIGFYKNEPIFLIGSTNCGK
SSLFNRLLKSDLCKTIAKSNVQSAVVSNLPGTTLNILKFPMVNLSPTFSN
RRQKAKFLFSVGKLKSYTGEKYPILESSQLAAQPTRSQTFFELITYAHKD
NEITSNSYDKEAMLNEFATPKNYDQDKITTNKWLYDTPGLVNPDQIASYL
PKEDVDQLYQENNLSEPKIYILKEGLSLIFQNLARIDVLEVDKHIYLTIH
ARLTAEIVATDDIDRYFAENDHFTLYSFKKTLSPPLLDRIKSTVPDYDAE
NSTIPDLVPSDMEIETKGFNVSSADVVFSSIGWIGISGMENSTCKIRAWT
PAAIGCGKRVPSLIPYAVKRRGTRKAYSRQFHVH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR006073GTP_binding_domain
IPR027417P-loop_NTPase
Vocabulary: molecular function
TermDefinition
GO:0005525GTP binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 181..350
e-value: 1.2E-22
score: 82.5
NoneNo IPR availablePANTHERPTHR46406FAMILY NOT NAMEDcoord: 74..633
IPR006073GTP binding domainPFAMPF01926MMR_HSR1coord: 290..442
e-value: 4.7E-8
score: 33.1
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 189..454