U5 small nuclear ribonucleoprotein 200 kDa helicase

Overview


Name	U5 small nuclear ribonucleoprotein 200 kDa helicase
Smed ID	SMED30034055
Length (bp)	6505

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of U5 small nuclear ribonucleoprotein 200 kDa helicase (SMED30034055) t-SNE clustered cells

Violin plots show distribution of expression levels for U5 small nuclear ribonucleoprotein 200 kDa helicase (SMED30034055) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of U5 small nuclear ribonucleoprotein 200 kDa helicase (SMED30034055) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034055

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30034055	SMESG000004936.1	SmedASXL_019661	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
epidermis	SMED30034055	SMESG000004936.1	dd_Smed_v4_3022_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30034055	SMESG000004936.1	dd_Smed_v4_3022_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30034055	SMESG000004936.1	dd_Smed_v4_3022_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30034055	SMESG000004936.1	dd_Smed_v4_3022_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior side	SMED30034055	SMESG000004936.1	dd_Smed_v4_7728_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior muscle cell	SMED30034055	SMESG000004936.1	dd_Smed_v4_7728_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034055	SMESG000004936.1	Contig39822	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034055	SMESG000004936.1	Contig39822	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
epidermis	SMED30034055	SMESG000004936.1	dd_Smed_v4_3022_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Human
Match: SNRNP200 (small nuclear ribonucleoprotein U5 subunit 200 [Source:HGNC Symbol;Acc:HGNC:30859])

HSP 1 Score: 2326.59 bits (6028), Expect = 0.000e+0
Identity = 1173/2156 (54.41%), Postives = 1570/2156 (72.82%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXX----XXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISN-YGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  +MG +  + KP   EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  L DKER+K    LLG    DT+Y+ LV+L  K+TDY   K   N +         ++  E D+++ +E+       + S+ D  G EA    TL+ +  A+G +                      +  + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR++++MI YCT L  +Q+  E+ +I  +M+ DP+ ++ L  L   + KED++  ER+R+ + R +++  D+E  D +          +LDL+++ FTQGSH M NK C+LPDGSFR+ + GY  V VPA KPKP  ++E L+ +  LP Y +A FE  KTLNRIQSK+Y+ ALE+DEN+LLCAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SF +RL +Y + VA L+GD  L +EEI+ TQIIVCTPEKWDII+RK  E+TYTQLV+L+I+DEIHLLHD+RGPVLEA+VAR +R ++ +    D+R++GLSATLPN ED+A F+ VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF DKHIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ++SKL D LNAEIV+G V+N  ++++WL Y YLYIRM ++P+LYG+  + L  DP LD    +L++TAA +L+K  ++ +DK++G F   E+GRIA++YY TN+T+    + LK ++ +IE+F+VFS  +EF+NITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQA+ISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   L  CK +++RMW   CPLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+H  PKL L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+     + RCVY+T +  LA+  Y +W + F   L K V+ LTG T+ D K + K +II+ST E WD+LSRRWK++K +QNI LF+VD++HLIG + NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+DV  WL C  T+T+NF+P+VR  PL++ IQ FNI+H  TRL +M+KPVY  I K SP  PVIVFVP+ KQT   A  ++    +D  ++ F   +E  +  Y+  +S+  L ETL  GVG++HE LS  ER L+ +LFSS +IQ++V S +LCW +   A+LVI+MDTQ YNGK   Y DY   D++QMVG AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH +HDHFNAEIVTKTIENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVE TL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +KVR L+E+I NA E+E++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+PHF     ++RC   GV++VFD+ME+EDE++ AL+   D ++ DVARF   YPNI+L+YEV    S+ +GG V V + L R+E+    V A  FP KREE WW+V+G+     LISIK L+     KV L+F AP  +G++ YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQP-RDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQT-DDTRYHVLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMS--------------------SKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETE-KEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQE--DVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEH-IKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAP-ATGAHNYTLYFMSDAYMGCDQEYKFSVDV 2126

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Human
Match: SNRNP200 (small nuclear ribonucleoprotein U5 subunit 200 [Source:HGNC Symbol;Acc:HGNC:30859])

HSP 1 Score: 1466.44 bits (3795), Expect = 0.000e+0
Identity = 748/1400 (53.43%), Postives = 1011/1400 (72.21%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXX----XXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISN-YGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDAR 4218
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  +MG +  + KP   EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  L DKER+K    LLG    DT+Y+ LV+L  K+TDY   K   N +         ++  E D+++ +E+       + S+ D  G EA    TL+ +  A+G +                      +  + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR++++MI YCT L  +Q+  E+ +I  +M+ DP+ ++ L  L   + KED++  ER+R+ + R +++  D+E  D +          +LDL+++ FTQGSH M NK C+LPDGSFR+ + GY  V VPA KPKP  ++E L+ +  LP Y +A FE  KTLNRIQSK+Y+ ALE+DEN+LLCAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SF +RL +Y + VA L+GD  L +EEI+ TQIIVCTPEKWDII+RK  E+TYTQLV+L+I+DEIHLLHD+RGPVLEA+VAR +R ++ +    D+R++GLSATLPN ED+A F+ VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF DKHIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ++SKL D LNAEIV+G V+N  ++++WL Y YLYIRM ++P+LYG+  + L  DP LD    +L++TAA +L+K  ++ +DK++G F   E+GRIA++YY TN+T+    + LK ++ +IE+F+VFS  +EF+NITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQA+ISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   L  CK +++RMW   CPLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+H  PKL L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+     + R
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQP-RDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQT-DDTRYHVLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMS--------------------SKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETE-KEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQE--DVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGR 1375

HSP 2 Score: 279.641 bits (714), Expect = 2.306e-75
Identity = 191/696 (27.44%), Postives = 342/696 (49.14%), Query Frame = 1

Query: 3991 ELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFS---------NRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHT-ATYNFNPSVRHRPLDIEIQTF-NITHNAT--RLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKK-----NFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAI---------KDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE 5994
            +LL ++KLP       +Y     +     N IQ++ + +   +DEN+ + APTG+GKT  A + ++R            N  D + +Y+  +  L Q     + K     G TV +LTG+  +  + IS   IIV T E WD+++R+  ++   Q ++L I+D++HL+     G  LE + +R        +  +R+IGLS +L N  DV  +L        + F+ S R  PL+   QT+  IT      R   M++ VY+ I++ +  + V+VFV + K+T + A  +    L           G AS  ++        N  L + L  G    H  ++  +R L+ +LF+ + IQ+LV + TL W +   A+ VI+  TQVY+ +   + +  A+D++QM+GRA     D     +++    +  +    L++ LP+ES +  +L D  NAEIV   ++N +DAV++L + +LY RM R+P  Y   G+SH  L      L++   +DL ++  + +         K   +     LG IA+ YYI   T++ ++  LKP      L  +   ++EF+++ +R  E + L ++ + + +P+ E   + +P  K N+LLQA++S++ ++   L  D+  +   + RL++A  +++ +  W       + L +MI +  W     L+Q     E
Sbjct:  460 QLLPVEKLP-------KYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLL-HDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLE---QTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLY---GISHDDLKG--DPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKES--IEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPE 1137

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Human
Match: ASCC3 (activating signal cointegrator 1 complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:18697])

HSP 1 Score: 1338.55 bits (3463), Expect = 0.000e+0
Identity = 764/1928 (39.63%), Postives = 1140/1928 (59.13%), Query Frame = 1

Query:  991 ELENKLL--RIVGVDRF--------------DLVRMLRENKLMIYYCT--------KLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKI---QADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVM-EYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLID-DPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLL--KEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALS--DKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAI-KDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPI-SEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE---------------------------PKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKS----VSAGGQVSVQIHLA--RDEDNISSVYANN----------------------------FPYKREESWWLVVGEPNQGHLISIKLLSSPTEK--VSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            EL  KLL  RI  VDRF              +  ++L EN    Y C         K    Q   E  +I    K   +   +   L   D KE  +  E+     ARS  I   Q D ++E  +    Y S     +K   F  G+ ++      LP+G  R+    Y  V +P  +P PL  +E  V I DL    + AF+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI +H    G I+K++FKIVY+APMK+L  EM + FS RL+   + V  L+GD  LS+ EI  TQ++V TPEKWD+++RKS  +   +Q+V+LLI+DE+HLLH++RGPVLE+IVART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+ + GLF FD  +RPVP+ Q +LGI     ++++  M+++ YE V+ +    HQV++FVH+R  TV TA ++ E+  N   +  F   +    ++ ++ + + +N  +++L P GF++HHAG+   DRN VE LF++ HI+VLV T+TLAWGVNLPAH VIIKGTQ+Y   +G + +L  LDVMQ+FGRAGRPQ+D  G GI+IT  ++L++YL+LL ++ PIESQ +  LADNLNAEI +GTV N+ E++ W+ YTYLY+RMR NP  YG+ +     DPTL  H   L+      L+KA+MI F++R+G F S ++GR A++YY    T++   +       + ++F + SK  EF  I VREE+  E+  LL N   +    G E+   KIN LLQ YIS+ +++ F+L SD+AY++Q+AAR++RA+FE+ L K+W ++T  +L   K +++R+W  + PLRQF  +P  I  +LE+K +  D+L D +  E+G ++++  +G  + + +HQIP + ++  +QPITR+ ++V L+I  DF W  + HG+  + +WI+VED  +++I H EYFL   K+    +  +L F + I++PLP  YYIRAVSD+W+G E    I F +++LPE++ P TELLDLQ LP  AL  + YE++Y+   S FN +QTQ F +LY++D NV +GAPTGSGKTV AE+AI R+F+    ++ VY+  L  L + R  +W ++    LGK VI+LTG+   D KSI+KA +IV+T E WD +SR W+ +  +Q + + I+D++HL+G +  G  LEVI SRT ++SS  E P+RI+GLS +L NARD+ +WL+      +NF PSVR  PL++ IQ F   H   R+A+M+KP +Q I   SP  PV++FV + +QT   A  L+ +  +  D K +    E  +   +  + +  L  TL+ G+G  H  L   +R  + ELF +  +Q+L+ + TL W +   A+LVI+  T+ Y+GK   Y D+   D++QM+GRA     DD  ++VI+    KKDF +KFL+EP P+ES L   L DH NAEI   TI +KQDA+DY+TWT+ + R+  NP+YYNL  VSH  ++  LS L+E +L++LE S CI I +D+  +  +  G IA++YY+ + T++MF   LKP      LL ++ +A E+ DLP+RH ED + + + +   LPI S       P TKA++LLQA+LSR  +   +   D   +L +++R+ QA +DV ++  WL   L    L QM+ Q +W +DS L  +P+                              P+L+  C   G   VF  M +E E   A       K +    F    P I++   V  S    V    ++SV    A  RD++    ++A+                             FP  ++E W+L++GE ++  LI++K +         SL+F  P   G Y YTLYFMSD YLG DQ+Y   +NV
Sbjct:  278 ELIEKLLQNRITIVDRFLNSSNDHRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEVSEGLMCFDPKELRIQREQAL-LNARSVPILSRQRDADVEKIHYPHVYDS-QAEAMKTSAFIAGAKMI------LPEGIQRENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQ-QGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMI--RILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYN--FSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGEE-RGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNSELAKC--LPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHARGRTSIESLPELIHAC--GGKDHVFSSM-VESELHAA-------KTKQAWNFLSHLPVINVGISVKGSWDDLVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGLDQQYDIYLNV 2179

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Human
Match: HFM1 (helicase for meiosis 1 [Source:HGNC Symbol;Acc:HGNC:20193])

HSP 1 Score: 324.709 bits (831), Expect = 1.531e-89
Identity = 256/825 (31.03%), Postives = 430/825 (52.12%), Query Frame = 1

Query: 1336 FTQGSHLMTNKNC----ELPDGSFRKTKPGYNLVCVPAPKPKPLEAD-ENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSRE-EINETQIIVCTPEKWDIISRKSSEKTYTQLVKX-XXXXXXXXXXXXRGPVLEAIVARTMRAMQS-------SHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGL-FKFDSSYRPVPMEQEYLGI---NERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFL----KKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-----VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAM--FEVTLSKKWASLTLS-VLESCKEVEQRMWACSCPL-RQFKKVPWEITKKLEKKNI-PFDRLIDQKHHELGELVNNH-KMGKTIYKYIHQIPKLNLKIHLQPITR-STMKVELTIT 3708
            F   +++ T  N     E+ +G F+   P +++   P    +  E    +L  + ++P+  ++ F++    N IQSK +   L +D N ++CAPTG+GKT V  L + R +      +  +   + KIVY+AP+K+L ++  + + E+     L    L+GD+ +    EI    II+ TPEKWD ++RK  + +  QLV+L LI +   +  + RGP LE +V+R M+ +QS       + + I MR V +SAT+PN EDIAE++   +   +  K D S+RPV +++  LG    + +   K    +N  +   +  Y+ +   L+F  +RK     A       L +D   +   ++K     LQ+    V++  L+D+L  G A HHAG+  +DR  VE  FT   + VL +TSTLA GVNLPAH+V+IK T  Y    G + E S  D++QM GRAGRPQ+DT    +++T  +    Y+ +L  +  +ES L   L ++LNAEIV+ T+ +++ +++W+R T LYIR  KNPS YG  + L  D  ++   + L     + L   ++I  D+    F   E GR+ A+YY T ET   +KKF     K+++ D+    + + C EF +I +R  +K  +  L ++     +  P++   +    K+NCL+QA +  + ++ F L+ DTA I +  +R+ R +  F     KK+A L  S +L  C     ++W  S  + +Q +K+   ++  +    +  F ++ +    EL  ++N H   G  I + +  +PK  LK+  + ITR S    E+ +T
Sbjct:  213 FQYSANVFTANNAFSASEIGEGMFKA--PSFSVAFQPHDIQEVTENGLGSLKAVTEIPAKFRSIFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLL-----MEVPLPWLNIKIVYMAPIKALCSQRFDDWKEKFGPIGLNCKELTGDTVMDDLFEIQHAHIIMTTPEKWDSMTRKWRDNSLVQLVRLFLIDEVHIVKDENRGPTLEVVVSR-MKTVQSVSQTLKNTSTAIPMRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSNQTEFKFDLTLNYKIASVIQMYSDQKPTLVFCATRKGVQQAASV-----LVKDAKFIMTVEQKQR---LQKYAYSVRDSKLRDILKDGAAYHHAGMELSDRKVVEGAFTVGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYA--GGLFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTRDKYIQMLACRDTVESSLHRHLIEHLNAEIVLHTITDVNIAVEWIRSTLLYIRALKNPSHYGFASGLNKD-GIEAKLQELCLKNLNDLSSLDLIKMDE-GVNFKPTEAGRLMAWYYITFET---VKKFYTISGKETLSDL--VTLIAGCKEFLDIQLRINEKKTLNTLNKDPNRITIRFPMEGRIKTREMKVNCLIQAQLGCIPIQDFALTQDTAKIFRHGSRITRWLSDFVAAQEKKFAVLLNSLILAKC--FRCKLWENSLHVSKQLEKIGITLSNAIVNAGLTSFKKIEETDARELELILNRHPPFGTQIKETVMYLPKYELKV--EQITRYSDTTAEILVT 1008

HSP 2 Score: 282.337 bits (721), Expect = 4.571e-76
Identity = 188/653 (28.79%), Postives = 324/653 (49.62%), Query Frame = 1

Query: 4039 EYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQ----DARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNK-SISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLET--------PIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIE--IQTFNITHNATRLA---AMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNL-KGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQ-----SLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAME 5922
            ++ SI+ K+  +FN IQ++ F+ L  +D N  I APTGSGKTV  E+AI RL         + + VY+  +  L   R+ +W + FG +G    +LTG+T MD+   I  AHII++T E WD ++R+W+    +Q ++LF++D++H++  ++ G TLEV+ SR + + S  +T        P+R + +S ++ NA D+ EWL               HRP+ ++  +  F  + N T       ++  +   I   S   P +VF  T K  ++ A +L+  A   K       +  + +Y  ++ +  L + L  G  + H  + +++R ++   F+   + +L  + TL   +   A+LV++  T  Y G   ++++YS  D++QM+GRA     D  A +VIM + + +D   + L     +ES L   L +H NAEIV  TI +   AV+++  T LY R  +NP++Y    G++   +   L EL    L DL +   I + + ++      G +  +YYI + T++ F  ++     +  L+ LI    EF D+ LR  E   L  + +     ++R P+  + R+     K N L+QA L  +PI+   L +D  +I     R+           RWL   +AA E
Sbjct:  270 KFRSIF-KEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNIKIVYMAPIKALCSQRFDDWKEKFGPIGLNCKELTGDTVMDDLFEIQHAHIIMTTPEKWDSMTRKWRDNSLVQLVRLFLIDEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKNTSTAIPMRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSNQTEFKFDLTLNYKIASVIQMYSDQKPTLVFCATRKGVQQAASVLVKDA---KFIMTVEQKQRLQKYAYSVRDSKLRDILKDGAAYHHAGMELSDRKVVEGAFTVGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYAGG--LFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTRDKYIQMLACRDTVESSLHRHLIEHLNAEIVLHTITDVNIAVEWIRSTLLYIRALKNPSHYGFASGLNKDGIEAKLQELCLKNLNDLSSLDLIKMDEGVNFKPTEAGRLMAWYYITFETVKKF-YTISGKETLSDLVTLIAGCKEFLDIQLRINEKKTLNTLNKDPNRITIRFPM--EGRIKTREMKVNCLIQAQLGCIPIQDFALTQDTAKIFRHGSRI----------TRWLSDFVAAQE 903

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Human
Match: ASCC3 (activating signal cointegrator 1 complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:18697])

HSP 1 Score: 265.388 bits (677), Expect = 4.141e-74
Identity = 149/315 (47.30%), Postives = 217/315 (68.89%), Query Frame = 1

Query: 1321 LKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVM-EYAGKHQV 2259
            +K   F  G+ ++      LP+G  R+    Y  V +P  +P PL  +E  V I DL    + AF+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI +H    G I+K++FKIVY+APMK+L  EM + FS RL+   + V  L+GD  LS+ EI  TQ++V TPEKWD+++RKS  +   +Q+V+LLI+DE+HLLH++RGPVLE+IVART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+ + GLF FD  +RPVP+ Q +LGI     ++++  M+++ YE V+ +    HQV
Sbjct:  413 MKTSAFIAGAKMI------LPEGIQRENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQ-QGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMI--RILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQV 718

HSP 2 Score: 110.153 bits (274), Expect = 2.080e-23
Identity = 73/248 (29.44%), Postives = 123/248 (49.60%), Query Frame = 1

Query: 4036 EEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSN--------RQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAI-QNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCH-HTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILK 4749
            +E   +  K M   N IQ+  FE+ YN++EN+ I APTG+GKT  A + ++             + + + VYV  +  LA      + +    LG  V +LTG+  +    I +  ++V+T E WDV++R+     A+ Q ++L I+D++HL+  +  G  LE I +RT       ++ IRI+GLS +L N  DV  +L  + +   + F+   R  PL          +   +L  M +  Y+ +LK
Sbjct:  464 DEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLL-HEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLK 710

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Celegans
Match: snrp-200 (Putative U5 small nuclear ribonucleoprotein 200 kDa helicase [Source:UniProtKB/Swiss-Prot;Acc:Q9U2G0])

HSP 1 Score: 2080.45 bits (5389), Expect = 0.000e+0
Identity = 1070/2162 (49.49%), Postives = 1503/2162 (69.52%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLPIKDIDPKKM--GARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQKFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLI-DDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKK-MSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTIL----KLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDK--KNFGRASEA--IVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPIS-EDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKS-VSAGGQVSVQIHLARDEDN---ISSVYANNFPYKR-EESWWLVVGEPNQGHLISIK-LLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD +AR  Q+EY+ NSNLVL+ D  L DRR ++EPTGEVLPI D + +KM  G R +K K       QD++ KR + +     Q   +VL  D  +    Y P+T ETK  YE +L+ + + L +     +     DE+L+ LKN    DKE+KK  + LLG  LTD +   L++LS K++D+   +           +   E D D  E E        D E DDGG+  +              +      +  L   G+L + +  A    L+  DIDA W+QR+L+K+F DP   Q++  +++ +LK A +D++ EN+L+ ++G D+F+ ++ LR+N+LMI YCT L      +ER +IE +M++ P+ + ILA L+  D +  +V  E++++   +S K  A    E  +         MLDL ++TF+QGSHLM+NK CELPDGS+R+ K  Y  + VPA KP+P    E LV +++LP + + AF+  K+LNRIQS++  +AL S E++LLCAPTGAGKTNVALLTM++EIG H+  DG+++ D+FKIVYIAPMKSLV EM  SFS+RL  + + V  ++GD+ +S+E+   TQ+IVCTPEK+D+++RK  E+ Y Q+V+LLIIDEIHLLHD+RGPVLE+IV RT+R M+ +H   + R+VGLSATLPN +D+A F+ V K   L  FD+SYRPVP+EQ+Y+G+ E+KA+KR + MN++VY+K+ME+AGK QVL+FVHSRKET  TAKAI++ CL +DTL  F+R+  AST +L+ + ++ KN DLKDLLPYGFA+HHAG+   DR  VE+LF D+HIQVL ST+TLAWGVNLPAH VIIKGTQ+Y P+KG WTEL ALD+MQM GRAGRPQYD +G GI+ITN +EL YYLSL+N+QLP+ESQ++S+L D LNAE+V+GTV ++ E+ +WL YT+L++RM KNP+LYG+ +     DP L+    +LI+TA  +L+KA +I +DKRSG   + E+GRIA+++YCT E+M    K L ++  DI++F++FS  +EF+ ++VR+E+K+E++K+ E+ P+PIKE  ++   K N LLQAYISQLKLE F L +D  +++QSA RL RA+FE+ L + WA L   VL  CK V QR W    PL QFKK+P E+ + ++KKN  FDRL D   H+LG+L+   KMGK ++K+I Q PKL +   +QPITR+TM++ELTITPDF+W  K HGS++GFWIF+ED   E ILH+E+FLLK+KF +D+H++K  V ++DP+PPLYY+R VSD+WIG ET + I F +++LPEK  P TELLDLQ LP  A+ N+E+++++++     FN IQTQ F +++ S+ENV + AP GSGKT  AE+A++R F N  +A+ VY+T + D+A   Y +W +    A+G T++ LTG   MD K   +  +I+ST E WD +SRRWK++K++QN++LFI DDLH+IG+  NG   EV+CSRTRY+SSQLE+ +R++ LS SLTNARD+G WL C  +AT+NF PS R  PLD+EI++FN++HNA+R AAM +PVYQ I     KL P  P +VFVP  +QT  +A  L+  AL+D   K F R +E        + +I +E L E++SCGVGF+HE  +  + +++ +LF S +IQ+ VV   +C+ I   AYLV+VMDTQ YNGK  +Y+DY   D++ MVG AN   +D DA+ V+MCQT+K+ + +KFL +PLP+ESHLDH LHDHFNAEIVTKTIENKQDA+DYLTWT LY RMT+NPNYYNL+G +HRHLSD LSELVE TL DLENSKCIA+KD++D  ++NLGMIA++YYI Y TIE+FS+SLK  +K R L+E+I  ++EF ++P+RH EDVIL ++ +  RLP   ++++ +DP  K N+L+ A+LSRV +  AEL +D   I++++ RL+QACVDVLSSN WL PA+ AMEL+QM+TQA +  +  LKQ+PH +   LLER +A  V +VF+L+ELE++ +  ++     +L DVARF   YP+I++  E+    V++   + + + L RD D       V A  FP KR EE WWLV+G+     L++IK L+ +    V L+F APR  G +++ L+F+SDSYLG DQE+     V
Sbjct:    1 MADELARIQQYEYRQNSNLVLSVDYNLTDRRGREEPTGEVLPITDKEMRKMKMGDRAIKGKAPV----QDQKKKRKKKDDEKAQQFGRNVLV-DNNELMGAYKPRTQETKQTYEVILSFILDALGDVP-REVLCGAADEVLLTLKNDKFRDKEKKKEVEALLGP-LTDDRIAVLINLSKKISDFSIEE-----------ENKPEGDGDIYENEGVNVQFDSDEEEDDGGMVNEIKGDSEEESEEEEGVDT--DYTATLKGDGHLTEDEQKARG-ILHPRDIDAHWIQRSLAKYFKDPLIAQQKQTEVIGILKNAADDRDAENQLVLLLGFDQFEFIKCLRQNRLMILYCT-LLRQANEKERLQIEDDMRSRPELHPILALLQETD-EGSVVQVEKSKRDAEKSKK-AATAANEAISAGQWQAGRKMLDLNDLTFSQGSHLMSNKRCELPDGSYRRQKKSYEEIHVPALKPRPFAEGEKLVSVSELPKWAQPAFDGYKSLNRIQSRLCDSALRSKEHLLLCAPTGAGKTNVALLTMLQEIGNHLAEDGSVKLDEFKIVYIAPMKSLVQEMVGSFSKRLAPFGITVGEMTGDAQMSKEQFMATQVIVCTPEKYDVVTRKGGERAYNQMVRLLIIDEIHLLHDDRGPVLESIVVRTIRQMEQNHD--ECRLVGLSATLPNYQDVATFLRV-KPEHLHFFDNSYRPVPLEQQYIGVTEKKALKRFQAMNEVVYDKIMEHAGKSQVLVFVHSRKETAKTAKAIRDACLEKDTLSAFMREGSASTEILRTEAEQAKNLDLKDLLPYGFAIHHAGMNRVDRTLVEDLFADRHIQVLFSTATLAWGVNLPAHTVIIKGTQIYNPEKGRWTELGALDIMQMLGRAGRPQYDDRGEGILITNHSELQYYLSLMNQQLPVESQMVSRLTDMLNAEVVLGTVSSVSEATNWLGYTFLFVRMLKNPTLYGITHEQARADPLLEQRRADLIHTACVLLDKAGLIKYDKRSGIIQATELGRIASHFYCTYESMQTYNKLLVETCSDIDLFRIFSMSSEFKLLSVRDEEKLELQKMAEHAPIPIKENLDEASAKTNVLLQAYISQLKLEGFALQADMVFVAQSAGRLFRALFEIVLWRGWAGLAQKVLTLCKMVTQRQWGSLNPLHQFKKIPSEVVRSIDKKNYSFDRLYDLDQHQLGDLIKMPKMGKPLFKFIRQFPKLEMTTLIQPITRTTMRIELTITPDFKWDEKVHGSAEGFWIFIEDTDGEKILHHEFFLLKQKFCSDEHVVKMIVPMFDPMPPLYYVRIVSDRWIGAETVLPISFRHLILPEKYPPPTELLDLQPLPISAVTNKEFQTVFAESGFKVFNPIQTQVFRTVFESNENVIVCAPNGSGKTAIAELAVLRHFENTPEAKAVYITPMEDMATKVYADWKRRLEPAIGHTIVLLTGEQTMDLKLAQRGQLIISTPERWDNISRRWKQRKSVQNVKLFIADDLHMIGAS-NGAVFEVVCSRTRYISSQLESAVRVVALSSSLTNARDLGMWLGCSASATFNFMPSTRPVPLDLEIKSFNLSHNASRFAAMERPVYQAICRHAGKLEPK-PALVFVPVRRQTRPVAVALLTMALADGAPKRFLRLAEHDDTFQALLADIEDESLRESVSCGVGFLHEGTAPKDVHIVQQLFESNAIQVCVVPRGMCYQIEMSAYLVVVMDTQFYNGKYHVYEDYPIADMLHMVGLANRPILDSDAKCVVMCQTSKRAYYKKFLCDPLPVESHLDHCLHDHFNAEIVTKTIENKQDAIDYLTWTLLYRRMTQNPNYYNLQGTTHRHLSDALSELVELTLKDLENSKCIAVKDEMDTVSLNLGMIASYYYISYQTIELFSMSLKEKTKTRALIEIISASSEFGNVPMRHKEDVILRQLAE--RLPGQLKNQKFTDPHVKVNLLIHAHLSRVKL-TAELNKDTELIVLRACRLVQACVDVLSSNGWLSPAIHAMELSQMLTQAMYSNEPYLKQLPHCS-AALLERAKAKEVTSVFELLELENDDRSDILQMEGAELADVARFCNHYPSIEVATELENDVVTSNDNLMLAVSLERDNDIDGLAPPVVAPLFPQKRKEEGWWLVIGDSESNALLTIKRLVINEKSSVQLDFAAPR-PGHHKFKLFFISDSYLGADQEFDVAFKV 2128

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Celegans
Match: Y54E2A.4 (pep chromosome:WBcel235:II:14754622:14778149:1 gene:WBGene00013189.1 transcript:Y54E2A.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y54E2A.4)

HSP 1 Score: 1082.4 bits (2798), Expect = 0.000e+0
Identity = 679/1955 (34.73%), Postives = 1077/1955 (55.09%), Query Frame = 1

Query:  925 PNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTK----------------------------LCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKE-DIVTAE--RNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNC---ELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVK-RIELMNDLVYEKVMEYAGK-HQVLIFVHSRKETVNTAKAIKEKCLNRDTLG---LFLRDKKASTLVLQQD--LDKVKNH-DLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVE-NVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKS---------MGDIEVFKVFSKCAEFRNITVRXXXXX-XXXXXXXNVPVPIKEGA-EDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKV---PWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSS--QGFWIFVEDVMSENILHYEYFLLKEKFKN--DDHILKFYVSIYD-PLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQ---LETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDK--KNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDV-SAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE------------PKLLERCEAAGVKTVFDLMELEDEQKL-----------------ALMNFP---DDKLQDVARFFQCYPNIDLTYEVSKSVSAGGQVSVQIHLAR--DEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS---SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            P+  +  ++++L++L   ++D +L+ +L+ ++GV+ F+L   + E +  I +  K                               SQ  + R   + E +T  + NR++    + ++ E ++   E  R R+ +    K +  +      +   Y  V    L+N+      H M + N     LP+GS R T   +  V VP      +E  ++ V + D+    +  F+  + LN IQS V++ A ++ EN+L+CAPTGAGKTN+A+LT++  I +H N+ G I KDDFKI+YIAPMK+L  EM  SF +RL    LKV  L+GD+ LSR E+ +TQ++V TPEKWD+I+RKS S+ +   +V+LLIIDE+HLLHDERGPV+E +VART+R ++ S S I  RIVGLSATLPN  D+A F+ V+ ++GLF FD  +RPVP+ Q+++G  +    +  + LM+++ Y++V+++  + HQVL+FVH+R  T    +A    C     LG   LFL   +AS+  +Q D  ++  +N   +  L   G  +HHAGL   DR  +E  F + H+ VL  T+TLAWGVNLPAH V+IKGT V+  +KG +T+L  LDV Q+FGRAGRPQ++ +G GI+IT  +++  YL++L  Q PIESQ  ++L DNLNAE+ +GTV  + E ++WL YTY+Y R  KNP  YG+  N +  DP L +H  N+I  AA  L++ +MI FD  +    S ++GRIA+ +Y   ET+ +L +  K           M D  V  + S   EF N+  REE+     + +     + ++ G       K+N LLQ+ IS+       L S+  Y+ Q+A RL RAMFE+ L   W+    + L   K VE++MW   C LRQF ++   P    +K+E+K      L++    +LG + +    G  +Y Y+  +P+++++   +PIT + ++VE+T+TP F W  + HG S  Q F++ +E++    I+H E   + +   N  +   L F + I D  L   + +R  S+ ++  +  + +   N +LP+     T+LLDL+ LP K L+N ++E+IY+    +FN IQ Q F  LY +D++  IGAPTGSGKT+CAE+A+ RL  +    + VY+  L  L + R  +W K F   +G  V++++G+   D + ++ + I+++T E WD +SR W  ++ ++ + L ++D++HL+G    G  LE I SR + ++ +    E P+R++GLS +L NA DV EWL     A YNF PSVR  P+ + IQ F   H   R+  M+KP Y+ IL  SP  PV++FV + +QT   A   +   ++D   K +       + + M  I +E L  TL  G+G  H  LS +ER ++ +LF  + IQ+L+ + TL W I   A+LVIV  T+ ++GK   Y D+   D++QM+GRA     DD A +VI  Q  KK F +KFL+EP P+ES L   L +H NAEI   TI++KQ  V+YL+ T+LY R+  NPNYY L+  S   +   ++++V++++ +L  S+CI +  + DV      G IA+ YY+ + T+     SL     V  +L+++ +  E+ ++P+RH ED+I T +++ LR+  S    +     KA++L QA+  R  +   + + DL  +L + +R++QA  ++     WL   +  + L QM   A+WH D  L  +PH +             P+L    E     ++ D       QKL                 AL N+P      +Q V     C  +ID T +  K V+AG    ++I + R     N SS++   +P  ++  W +VVG  +   +++   ++   S      L+  AP   G++E  +  +SD YLG DQEY   ++V
Sbjct:   82 PDTFETISQNLLQMLCSTRSDMDLQGELIDLLGVELFELAGDILEKRNKIVFEVKSQELAKVEHARQAKAKPAVPGFLQTVSVQSTSQNEKRRELRKEEKRTRRELNRVIHAFGDEEKLELELAQKEIQRQRQLEIDQMKWKPSLVAGGPRIEEIYPYVFDARLQNV-----GHTMFDINGMKFALPEGSKRDTFKTHESVYVPPSNKGDIEKIQH-VYVKDMDELGQKGFKGFEKLNVIQSIVFEQAYKTKENLLICAPTGAGKTNIAMLTILNTIHEHQNSRGDIMKDDFKIIYIAPMKALATEMTESFGKRLAPLGLKVKELTGDTQLSRNEVADTQMLVLTPEKWDVITRKSTSDNSLINVVRLLIIDEVHLLHDERGPVIETLVARTLRQVEMSQSGI--RIVGLSATLPNFIDVARFLRVNPYKGLFFFDGRFRPVPLTQKFIGTRKAGNFRDNLTLMDNVCYDEVVDFVKRGHQVLVFVHTRNGTAKLGEAF---CARASVLGQMDLFLPKDRASSKYIQADKAINICRNRAQISPLFQRGMGIHHAGLCRQDRILMERCFAEGHVSVLFCTATLAWGVNLPAHAVVIKGTDVFDAEKGVFTDLGVLDVQQIFGRAGRPQFENEGHGIIITTRDKIDKYLTMLVHQNPIESQFYARLHDNLNAEVALGTVSTVDEGVEWLTYTYMYTRALKNPMAYGIAYNAIERDPNLRDHFGNVIREAAMQLDQNKMIRFDMATEYLNSTDLGRIASNFYVKYETIQLLNEAEKGVGLPVTFTSFMPDDMVIGLISMSTEFANLKCREEEIGDLEELMSYGCMMNVRGGGLASVAGKVNVLLQSLISRTSTRNSALMSEQLYVQQNAGRLCRAMFEMVLKNGWSQAANAFLGIAKCVEKQMWMNQCALRQFIQIINIPITWIEKIERKKARESDLLELSAKDLGYMFSCD--GDRLYTYLRYLPRMDVQAKFKPITYTIVQVEVTLTPTFIWNDQIHGKSGQQSFYLVLENLNENLIIHQERIGIGKMKVNRQETQNLVFTIPIVDCQLTNNFQLRLASEYFVTDDVVVPMSLHNCILPKSFKSHTDLLDLEPLPIKTLKNSKFEAIYN--FDYFNPIQAQVFFCLYKTDKSALIGAPTGSGKTLCAELAMFRLLQDHPGMKVVYIAPLKSLVRERVDDWKKKFEDGMGYRVVEVSGDVTPDPEELAASSILITTPEKWDGISRSWATREYVRRVGLIVLDEVHLLGVDR-GAVLEAIVSRLKMITRRSHVTEEPVRLLGLSTALANAGDVAEWLGIPDEACYNFRPSVRPVPISVHIQGFPGQHYCPRMGLMNKPAYKAILTYSPRKPVLIFVSSRRQTRLTALAFVNLLIADHNPKQWLNMDMLELEDLMAAIKDENLKLTLPFGIGMHHAGLSAHERAIVEQLFIEKKIQVLIATATLAWGINCPAHLVIVKGTEYFDGKKGKYVDFPVTDVLQMMGRAGRPQFDDSAVAVIYVQDAKKTFYKKFLYEPFPVESSLLPVLPNHVNAEISAGTIDSKQAIVEYLSKTYLYRRLFANPNYYGLEEDSEEAMLKFITKIVDDSVAELLASECIHVDSEQDVIKPTPCGRIASVYYLQHETVRFLVKSLHSGCSVENMLKILTDVPEYAEIPVRHNEDLINTELQKKLRIRFSTSV-MGTSACKAHLLFQAHFMRT-VLPTDYRTDLKSVLDQCIRILQAMREMARLKNWLSATMNIILLQQMCHSARWHDDHPLLCLPHLSHEDARSIGDGMTIPQLQNHLEIEKSTSLDDAKLARRAQKLFRECTKLDEAQSREVLKALCNWPIINMKIMQLVDSRGNCV-DIDETKKPVK-VTAGEVYKLRIVMERVGPGKNNSSMHLPQWPKPKQAGWIIVVGNVSADMILNTTTVTGSHSTRSTAKLDIRAPATKGNHELAVLILSDCYLGIDQEYTLRLDV 2016

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Celegans
Match: Y54E2A.4 (pep chromosome:WBcel235:II:14768462:14778149:1 gene:WBGene00013189.1 transcript:Y54E2A.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y54E2A.4)

HSP 1 Score: 687.567 bits (1773), Expect = 0.000e+0
Identity = 431/1307 (32.98%), Postives = 695/1307 (53.18%), Query Frame = 1

Query: 2740 LLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVE-NVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKS---------MGDIEVFKVFSKCAEFRNITVRXXXXX-XXXXXXXNVPVPIKEGA-EDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKV---PWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSS--QGFWIFVEDVMSENILHYEYFLLKEKFKN--DDHILKFYVSIYD-PLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQ---LETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDK--KNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDV-SAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE------------PKLLERCEAAGVKTVFDLMELEDEQKL-----------------ALMNFP---DDKLQDVARFFQCYPNIDLTYEVSKSVSAGGQVSVQIHLAR--DEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS---SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            +L  Q PIESQ  ++L DNLNAE+ +GTV  + E ++WL YTY+Y R  KNP  YG+  N +  DP L +H  N+I  AA  L++ +MI FD  +    S ++GRIA+ +Y   ET+ +L +  K           M D  V  + S   EF N+  REE+     + +     + ++ G       K+N LLQ+ IS+       L S+  Y+ Q+A RL RAMFE+ L   W+    + L   K VE++MW   C LRQF ++   P    +K+E+K      L++    +LG + +    G  +Y Y+  +P+++++   +PIT + ++VE+T+TP F W  + HG S  Q F++ +E++    I+H E   + +   N  +   L F + I D  L   + +R  S+ ++  +  + +   N +LP+     T+LLDL+ LP K L+N ++E+IY+    +FN IQ Q F  LY +D++  IGAPTGSGKT+CAE+A+ RL  +    + VY+  L  L + R  +W K F   +G  V++++G+   D + ++ + I+++T E WD +SR W  ++ ++ + L ++D++HL+G    G  LE I SR + ++ +    E P+R++GLS +L NA DV EWL     A YNF PSVR  P+ + IQ F   H   R+  M+KP Y+ IL  SP  PV++FV + +QT   A   +   ++D   K +       + + M  I +E L  TL  G+G  H  LS +ER ++ +LF  + IQ+L+ + TL W I   A+LVIV  T+ ++GK   Y D+   D++QM+GRA     DD A +VI  Q  KK F +KFL+EP P+ES L   L +H NAEI   TI++KQ  V+YL+ T+LY R+  NPNYY L+  S   +   ++++V++++ +L  S+CI +  + DV      G IA+ YY+ + T+     SL     V  +L+++ +  E+ ++P+RH ED+I T +++ LR+  S    +     KA++L QA+  R  +   + + DL  +L + +R++QA  ++     WL   +  + L QM   A+WH D  L  +PH +             P+L    E     ++ D       QKL                 AL N+P      +Q V     C  +ID T +  K V+AG    ++I + R     N SS++   +P  ++  W +VVG  +   +++   ++   S      L+  AP   G++E  +  +SD YLG DQEY   ++V
Sbjct:    1 MLVHQNPIESQFYARLHDNLNAEVALGTVSTVDEGVEWLTYTYMYTRALKNPMAYGIAYNAIERDPNLRDHFGNVIREAAMQLDQNKMIRFDMATEYLNSTDLGRIASNFYVKYETIQLLNEAEKGVGLPVTFTSFMPDDMVIGLISMSTEFANLKCREEEIGDLEELMSYGCMMNVRGGGLASVAGKVNVLLQSLISRTSTRNSALMSEQLYVQQNAGRLCRAMFEMVLKNGWSQAANAFLGIAKCVEKQMWMNQCALRQFIQIINIPITWIEKIERKKARESDLLELSAKDLGYMFSCD--GDRLYTYLRYLPRMDVQAKFKPITYTIVQVEVTLTPTFIWNDQIHGKSGQQSFYLVLENLNENLIIHQERIGIGKMKVNRQETQNLVFTIPIVDCQLTNNFQLRLASEYFVTDDVVVPMSLHNCILPKSFKSHTDLLDLEPLPIKTLKNSKFEAIYN--FDYFNPIQAQVFFCLYKTDKSALIGAPTGSGKTLCAELAMFRLLQDHPGMKVVYIAPLKSLVRERVDDWKKKFEDGMGYRVVEVSGDVTPDPEELAASSILITTPEKWDGISRSWATREYVRRVGLIVLDEVHLLGVDR-GAVLEAIVSRLKMITRRSHVTEEPVRLLGLSTALANAGDVAEWLGIPDEACYNFRPSVRPVPISVHIQGFPGQHYCPRMGLMNKPAYKAILTYSPRKPVLIFVSSRRQTRLTALAFVNLLIADHNPKQWLNMDMLELEDLMAAIKDENLKLTLPFGIGMHHAGLSAHERAIVEQLFIEKKIQVLIATATLAWGINCPAHLVIVKGTEYFDGKKGKYVDFPVTDVLQMMGRAGRPQFDDSAVAVIYVQDAKKTFYKKFLYEPFPVESSLLPVLPNHVNAEISAGTIDSKQAIVEYLSKTYLYRRLFANPNYYGLEEDSEEAMLKFITKIVDDSVAELLASECIHVDSEQDVIKPTPCGRIASVYYLQHETVRFLVKSLHSGCSVENMLKILTDVPEYAEIPVRHNEDLINTELQKKLRIRFSTSV-MGTSACKAHLLFQAHFMRT-VLPTDYRTDLKSVLDQCIRILQAMREMARLKNWLSATMNIILLQQMCHSARWHDDHPLLCLPHLSHEDARSIGDGMTIPQLQNHLEIEKSTSLDDAKLARRAQKLFRECTKLDEAQSREVLKALCNWPIINMKIMQLVDSRGNCV-DIDETKKPVK-VTAGEVYKLRIVMERVGPGKNNSSMHLPQWPKPKQAGWIIVVGNVSADMILNTTTVTGSHSTRSTAKLDIRAPATKGNHELAVLILSDCYLGIDQEYTLRLDV 1298

HSP 2 Score: 335.109 bits (858), Expect = 7.973e-94
Identity = 223/687 (32.46%), Postives = 361/687 (52.55%), Query Frame = 1

Query: 1444 PKPLEADENLVKIADLP--SYVKAAFEKIKTL---NRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLK-SYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNID-MRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGA-EDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPL 3480
            PK  ++  +L+ +  LP  +   + FE I      N IQ++V+    ++D++ L+ APTG+GKT  A L M R +  H            K+VYIAP+KSLV E  + + ++ +     +V  +SGD     EE+  + I++ TPEKWD ISR  + + Y + V L+++DE+HLL  +RG VLEAIV+R     + SH   + +R++GLS  L N  D+AE++ +      + F  S RPVP+     G   +    R+ LMN   Y+ ++ Y+ +  VLIFV SR++T  TA A     +       +L       L L+  +  +K+ +LK  LP+G  +HHAGL+  +R  VE+LF +K IQVL++T+TLAWG+N PAH+VI+KGT+ +   KG++ +    DV+QM GRAGRPQ+D   V ++   + + T+Y   L E  P+ES L+  L +++NAEI  GT+ +    +++L  TYLY R+  NP+ YG+E     +  +      ++  + + L  +E I+ D           GRIA+ YY  +ET+  L K L        + K+ +   E+  I VR  + +   +L + + +            K + L QA+  +  L      +D   +     R+++AM E+   K W S T++++   +      W    PL
Sbjct:  428 PKSFKSHTDLLDLEPLPIKTLKNSKFEAIYNFDYFNPIQAQVFFCLYKTDKSALIGAPTGSGKTLCAELAMFRLLQDH---------PGMKVVYIAPLKSLVRERVDDWKKKFEDGMGYRVVEVSGDVTPDPEELAASSILITTPEKWDGISRSWATREYVRRVGLIVLDEVHLLGVDRGAVLEAIVSRLKMITRRSHVTEEPVRLLGLSTALANAGDVAEWLGIPDE-ACYNFRPSVRPVPISVHIQGFPGQHYCPRMGLMNKPAYKAILTYSPRKPVLIFVSSRRQTRLTALAFVNLLIADHNPKQWL---NMDMLELEDLMAAIKDENLKLTLPFGIGMHHAGLSAHERAIVEQLFIEKKIQVLIATATLAWGINCPAHLVIVKGTEYFDGKKGKYVDFPVTDVLQMMGRAGRPQFDDSAVAVIYVQDAKKTFYKKFLYEPFPVESSLLPVLPNHVNAEISAGTIDSKQAIVEYLSKTYLYRRLFANPNYYGLEE--DSEEAMLKFITKIVDDSVAELLASECIHVDSEQDVIKPTPCGRIASVYYLQHETVRFLVKSLHSGCSVENMLKILTDVPEYAEIPVRHNEDLINTELQKKLRIRFSTSVMGTSACKAHLLFQAHFMRTVLPT-DYRTDLKSVLDQCIRILQAMREMARLKNWLSATMNIILLQQMCHSARWHDDHPL 1098

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Celegans
Match: Y54E2A.4 (pep chromosome:WBcel235:II:14773761:14778137:1 gene:WBGene00013189.1 transcript:Y54E2A.4c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y54E2A.4)

HSP 1 Score: 202.601 bits (514), Expect = 1.589e-55
Identity = 145/479 (30.27%), Postives = 238/479 (49.69%), Query Frame = 1

Query: 5146 MVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDV-SAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE------------PKLLERCEAAGVKTVFDLMELEDEQKL-----------------ALMNFP---DDKLQDVARFFQCYPNIDLTYEVSKSVSAGGQVSVQIHLAR--DEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS---SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            M+GRA     DD A +VI  Q  KK F +KFL+EP P+ES L   L +H NAEI   TI++KQ  V+YL+ T+LY R+  NPNYY L+  S   +   ++++V++++ +L  S+CI +  + DV      G IA+ YY+ + T+     SL     V  +L+++ +  E+ ++P+RH ED+I T +++ LR+  S    +     KA++L QA+  R  +   + + DL  +L + +R++QA  ++     WL   +  + L QM   A+WH D  L  +PH +             P+L    E     ++ D       QKL                 AL N+P      +Q V     C  +ID T +  K V+AG    ++I + R     N SS++   +P  ++  W +VVG  +   +++   ++   S      L+  AP   G++E  +  +SD YLG DQEY   ++V
Sbjct:    1 MMGRAGRPQFDDSAVAVIYVQDAKKTFYKKFLYEPFPVESSLLPVLPNHVNAEISAGTIDSKQAIVEYLSKTYLYRRLFANPNYYGLEEDSEEAMLKFITKIVDDSVAELLASECIHVDSEQDVIKPTPCGRIASVYYLQHETVRFLVKSLHSGCSVENMLKILTDVPEYAEIPVRHNEDLINTELQKKLRIRFSTSV-MGTSACKAHLLFQAHFMRT-VLPTDYRTDLKSVLDQCIRILQAMREMARLKNWLSATMNIILLQQMCHSARWHDDHPLLCLPHLSHEDARSIGDGMTIPQLQNHLEIEKSTSLDDAKLARRAQKLFRECTKLDEAQSREVLKALCNWPIINMKIMQLVDSRGNCV-DIDETKKPVK-VTAGEVYKLRIVMERVGPGKNNSSMHLPQWPKPKQAGWIIVVGNVSADMILNTTTVTGSHSTRSTAKLDIRAPATKGNHELAVLILSDCYLGIDQEYTLRLDV 475

HSP 2 Score: 103.99 bits (258), Expect = 1.747e-22
Identity = 71/261 (27.20%), Postives = 124/261 (47.51%), Query Frame = 1

Query: 2650 MFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGA-EDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVL 3429
            M GRAGRPQ+D   V ++   + + T+Y   L E  P+ES L+  L +++NAEI  GT+ +    +++L  TYLY R+  NP+ YG+E     +  +      ++  + + L  +E I+ D           GRIA+ YY  +ET+  L K L        + K+ +   E+  I VR  + +   +L + + +            K + L QA+  +  L      +D   +     R+++AM E+   K W S T++++
Sbjct:    1 MMGRAGRPQFDDSAVAVIYVQDAKKTFYKKFLYEPFPVESSLLPVLPNHVNAEISAGTIDSKQAIVEYLSKTYLYRRLFANPNYYGLEE--DSEEAMLKFITKIVDDSVAELLASECIHVDSEQDVIKPTPCGRIASVYYLQHETVRFLVKSLHSGCSVENMLKILTDVPEYAEIPVRHNEDLINTELQKKLRIRFSTSVMGTSACKAHLLFQAHFMRTVLPT-DYRTDLKSVLDQCIRILQAMREMARLKNWLSATMNII 258

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Celegans
Match: polq-1 (DNA polymerase theta [Source:UniProtKB/Swiss-Prot;Acc:A0FLQ6])

HSP 1 Score: 116.316 bits (290), Expect = 2.034e-25
Identity = 119/454 (26.21%), Postives = 216/454 (47.58%), Query Frame = 1

Query: 1510 AFEKIKTLNRIQSKVYKTALE-SDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKW-DIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQE-YLGINERKA----VKRIELMNDLVYEKVMEYAGKHQVLIFVHSR----KETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDK--VKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLAD----NLNAEIVMG 2820
            A + IK L   Q  V   A +  D++++  APT AGK+ VA L     +   + + G       K++++ P  S+  E  +      +  ++ V    G         NE    VCT EK   + +R  SE  + ++  +++ +   +    RG  +E ++++ +   QS+   +  RI+G+SAT+P    I +++      G   F++ +RP+ ++    +G   RK+    V R    + L+      +    Q L+ + S+    K  +N A    E      +L   L+++    L ++  L++   K+ ++   L +G A HHAGL   +R  +E  F +K+I +LV+TSTLA GVNLPA  V+IK  Q   P     + L++L+  QM GRAGR  + T+G   ++  + +    L ++  + PI+  ++++  D    NL+  I+ G
Sbjct:   21 AEQNIKALFDWQIDVLNEARQFEDQHLIFSAPTSAGKSIVAEL-----LSWKVASTGR------KVLFVLPYISVAREKLHQIQRCWRRDDISVCGFIGPQA---SNPNEWLGAVCTIEKAASLTNRALSEDWFEEIGMIVVDEMHMVFDSSRGAHIEHMLSKVLLWNQSALEKV--RIIGMSATIPELYRIGKWLD-----GAKVFEARFRPIVLQNHIVIGSELRKSGDNKVLREFSEDPLILLTEESFRRNSQTLVMISSKLDAEKTALNIASRFHEINKTDSSLLEILKERANGLLFIKHGLERNGCKDRNVMSTLAWGVAYHHAGLTMEERECIELGFREKNIVILVATSTLASGVNLPAERVLIKA-QPRGP-----SALTSLNYRQMVGRAGRTGHATRGETYLLIKKCDRDAVLKII--ETPIDQGVLTRKRDAERTNLSRFILEG 445

HSP 2 Score: 63.929 bits (154), Expect = 1.844e-9
Identity = 79/397 (19.90%), Postives = 165/397 (41.56%), Query Frame = 1

Query: 4120 DENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKP-VYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAIVSEYMRNISNEIL----------------IETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRA---NHASMDDARSVIMCQTNKKDFIQKFLHEPL 5250
            D+++   APT +GK++ AE+   ++ S  +  + ++V     +A+ +  +  + +     +V    G    +      A   V T E    L+ R   +   + I + +VD++H++     G  +E + S+    +      +RIIG+S ++     +G+WLD        F P V    + I  +      N         P +  T      NS  +V + +    E+ A       ++ + +    +++ + E ++  +N +L                + TL+ GV + H  L++ ER  +   F  ++I ILV + TL   +   A  V++       G   +    ++++  QMVGRA    HA+  +  + ++ +   +D + K +  P+
Sbjct:   44 DQHLIFSAPTSAGKSIVAELLSWKVASTGR--KVLFVLPYISVAREKLHQIQRCWRRDDISVCGFIGPQASNPNEWLGA---VCTIEKAASLTNRALSEDWFEEIGMIVVDEMHMVFDSSRGAHIEHMLSKVLLWNQSALEKVRIIGMSATIPELYRIGKWLDGAKVFEARFRPIVLQNHIVIGSELRKSGDNKVLREFSEDPLILLTEESFRRNSQTLVMISSKLDAEKTAL-----NIASRFHEINKTDSSLLEILKERANGLLFIKHGLERNGCKDRNVMSTLAWGVAYHHAGLTMEERECIELGFREKNIVILVATSTLASGVNLPAERVLIKAQP--RGPSAL----TSLNYRQMVGRAGRTGHATRGE--TYLLIKKCDRDAVLKIIETPI 422

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Fly
Match: l(3)72Ab (gene:FBgn0263599 transcript:FBtr0075527)

HSP 1 Score: 2276.13 bits (5897), Expect = 0.000e+0
Identity = 1152/2165 (53.21%), Postives = 1556/2165 (71.87%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDY---------KAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSV--DMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLID-DPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKK--NFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVIL----TRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR +Q+EYK NSNLVL AD  LI+R  +DE TGEV   +  +D  +MG R  + KP+  EE++ KR KRD++    +  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  L D+ERKK    LLG  +TD ++  LV+L  K+TD+          AP     E  D+T  ++++ ++ +EE ++D+YGE++D ++ D G EA  + TL+    A    +                   N+     L+  DIDA+WLQR LSK + D    Q +  D+L++LK A +D++ EN+L+ ++G D FD ++ L+ N+ M+ YCT L  +QT  ER +I  +M+ +    +IL       R+ D   +E   + +AR +K       +     +   +    +L+L+ + FTQGSH M NK C+LPDGS+RK + GY  V VPA KP P +A+E L  +  LP YV+  FE  KTLNRIQS++YK AL+SDEN+LLCAPTGAGKTNVALLTMMREIGKHIN DGTI   DFKI+Y+APMKSLV EM  +F  RL  YNL V+ L+GD  L+RE+I  TQ+IVCTPEKWDII+RK  E+T+  LV+L+IIDEIHLLHDERGPVLEA+VART+R ++++   +  R+VGLSATLPN +D+A F+ V   +GLF FD+SYRPV +EQ+Y+G+ E+KA+KR ++MN++VYEK ME+AG++QVL+FVHSRKET  TA+A+++ CL +DTLG FL++  AS  VL+ + ++VKN +LK+LLPYGFA+HHAG+   DR  VE+LF D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG W ELSALDV+QM GRAGRPQYDTKG GI+ITN +EL +YLSLLN+QLPIESQ ISKL D LNAEIV+GTV+++ ++++WL YTYLYIRM +NP+LYGV +  I  DP L+ H  +L++TAA  LE++ +I +D+++G F   ++GRIA++YY T+ETM    + LK+++ +IE+F+VFS  +EFR+I+VREE+K+E++KL+E VP+PIKE  E+   K+N LLQAYISQLKLE F L SD  +I+QSAARLMRA+FE+ L++ WA L    L  CK +++RMW    PLRQFKK+P EI KKLEKK+ P+ RL D + HELGEL+   K+GKTI+K++HQ PKL L  H+QPITR T++VELTITPDF+W  K HG S+GFW+ +EDV SE ILH+E+FLLK+K+  D+H LKF+V +++PLPP Y++R VSD+WIG ET++ + F +++LPEKN P TELLDLQ LP  ALR  ++ES YS++   FN IQTQ F ++YNSDENVF+GAPTGSGK   AE AIMRLF+ + DARCVY+ +   LA L + +W   FG+L   V+KLTG T  D K I+K  ++++TA+ WDVLSRRWK++K +Q + LFIVD+L L+G +  G  LE++CSR RY+SSQ+E  IRI+ LS SLT+ARDV +WL C+  AT+NF+PSVR  PL++ IQ +N+THNATR+A MSKPVY  ILK S + PVIVFV + KQ    A  ++ YA SD +   F  A E  +  ++  ++++ L ETL+ GV ++HE LS ++  L+ +LF S ++Q+ V+S  LCW +   A+LVI+MDTQ YNGK+  Y+DY   D++QM+GRAN  + D DA+ V+MCQ++KKDF +KF++EPLP+ESHLDH++HDHFNAE+VTKTIENKQDAVDYLTWTFLY R+T+NPNYYNL+GV+HRHLSDHLSELVENTL DLE SKCI+++DD+D   +NLGMIA +YYI+YTTIE+FSLSL   +KVR LLE+I +A E+ED+ +RH E+ +L     R+   L  P     + +DP  K N+LLQA+LSR+ +   EL+ D  QIL K++RLIQACVDVLSSN WL PA+AAMELAQM+TQA W +DS LKQ+PHF+ P++++RC    ++TVFD+MELEDE +  L+   D ++ DVARF   YPNI+L YEV     +++G  V+V + L R+++    V A  FP KREE WW+V+G+P    L+SIK L+     KV L+F AP   G ++YTLY+MSDSYLGCDQEY+F+I V
Sbjct:    1 MADAAARQLQYEYKANSNLVLQADVRLIERPRRDEATGEVCSLVGKLDGTRMGDRYQRTKPEKTEERKVKRQKRDEAQYDFERMKGATLLSEGIDEMVGIVYRPKTQETRQTYEVLLSFIQEALGDQP-RDILCGAADEILAVLKNDRLKDRERKKDIDSLLGA-VTDERFALLVNLGKKITDFGSDAVNALTAAPN--NEEQIDETYGINVQFEESEEESDNDMYGEIRDDDAQDEGEEARIDHTLHAENLANEEAA------------------NNVKKERSLHPLDIDAYWLQRCLSKFYKDAMVSQSKAADVLKILKDAADDRDCENQLVLLLGYDCFDFIKQLKLNRQMVLYCTMLASAQTDSERQRIREKMRGNSALAKIL-------RQLDTGKSEDQEEGEARGSKRGKGDAEDGGAAAAGQVAGVRQLLELEEMAFTQGSHFMANKRCQLPDGSYRKQRKGYEEVHVPALKPVPFDANEELQPVDKLPKYVQPVFEGFKTLNRIQSRLYKAALDSDENMLLCAPTGAGKTNVALLTMMREIGKHINEDGTINAQDFKIIYVAPMKSLVQEMVGNFGRRLACYNLTVSELTGDHQLTREQIAATQVIVCTPEKWDIITRKGGERTFVSLVRLVIIDEIHLLHDERGPVLEALVARTIRNIETTQEEV--RLVGLSATLPNYQDVATFLRVKPDKGLFYFDNSYRPVSLEQQYIGVTEKKALKRFQVMNEIVYEKTMEHAGRNQVLVFVHSRKETGKTARAVRDMCLEQDTLGSFLKEGSASMEVLRTEAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILITNHSELQFYLSLLNQQLPIESQFISKLPDMLNAEIVLGTVQHLQDAVNWLGYTYLYIRMLRNPTLYGVSHDAIKADPLLEQHRADLLHTAACCLERSGLIKYDRKTGHFQVTDLGRIASHYYLTHETMLTYNQLLKQTLSEIELFRVFSLSSEFRHISVREEEKLELQKLMERVPIPIKESIEEHSAKVNVLLQAYISQLKLEGFALMSDMVFITQSAARLMRAIFEIVLTRGWAQLADKTLTLCKMIDRRMWQSMTPLRQFKKMPDEIAKKLEKKHFPWGRLYDLEPHELGELIRVPKLGKTIHKFVHQFPKLELSTHIQPITRGTLRVELTITPDFQWDEKVHGQSEGFWVLIEDVDSELILHHEFFLLKQKYSQDEHQLKFFVPVFEPLPPQYFLRIVSDRWIGAETQLPVSFRHLILPEKNMPPTELLDLQPLPISALRQPKFESFYSQRFPQFNPIQTQVFNAVYNSDENVFVGAPTGSGKMTIAEFAIMRLFTTQSDARCVYLVSEEALADLVFADWHSKFGSLDIKVVKLTGETGTDLKLIAKGQLVITTADKWDVLSRRWKQRKNVQLVNLFIVDELQLVGGE-EGPVLEIVCSRMRYISSQIEKQIRIVALSASLTDARDVAQWLGCNPNATFNFHPSVRPIPLELHIQGYNVTHNATRIATMSKPVYNAILKYSAHKPVIVFVSSRKQARLTAIDVLTYAASDLQPNRFFHAEEEDIKPFLERMTDKTLKETLAQGVAYLHEGLSASDHRLVEQLFDSGAVQVAVISRDLCWGMSISAHLVIIMDTQFYNGKNHSYEDYPITDVLQMIGRANRPNEDADAKCVLMCQSSKKDFFKKFINEPLPIESHLDHRMHDHFNAEVVTKTIENKQDAVDYLTWTFLYRRLTQNPNYYNLQGVTHRHLSDHLSELVENTLSDLEQSKCISVEDDMDTLPLNLGMIAAYYYINYTTIELFSLSLNSKTKVRGLLEIISSAAEYEDVVVRHHEEQVLRTLSQRLPNKLTGPNETAPKFNDPHIKTNLLLQAHLSRLQL-GPELQGDTEQILSKAIRLIQACVDVLSSNGWLSPAVAAMELAQMVTQAMWSKDSYLKQLPHFS-PEIVKRCTEKKIETVFDIMELEDEDRTRLLQLSDLQMADVARFCNRYPNIELNYEVVDKDRINSGSTVNVVVQLEREDEVTGPVIAPFFPQKREEGWWVVIGDPKTNSLLSIKRLTLQQKAKVKLDFVAP-SPGKHDYTLYYMSDSYLGCDQEYKFSIEV 2130

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Fly
Match: obe (gene:FBgn0038344 transcript:FBtr0083147)

HSP 1 Score: 1202.19 bits (3109), Expect = 0.000e+0
Identity = 679/1772 (38.32%), Postives = 1034/1772 (58.35%), Query Frame = 1

Query: 1342 QGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSS-EKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGK-HQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVE-NVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKE--GAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSS-QGFWIFVEDVMSENILHYEYFLLKEKF--KNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF--GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYAL--SDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRL-PISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE-------------------PKLLERCE------AAGVKTVFDLMELE-------DEQKLALMNFPDDK------------LQDVAR--FFQCYPNIDLTYEVS-KSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLSSPTEKVS--LNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 6468
            Q +  +      LPD + R     +  V +PA +P PL      V+I +L    + AF   K LNRIQS V+  A  S+EN+L+CAPTGAGKTNVA+L+++  I  H+   G I +D+FKIVYIAPMK+L  EM ++FS+RLKS  + V  L+GD  L++ E+  TQI+V TPEKWD+++RK S +     LV+LLIIDE+HLLH ERGPV+EA+VART+R ++SS S I  RIVGLSATLPN  D+A F+ V+  +GLF FDS +RPVP++  ++GI   K +++I  M+   Y+K +E   + HQ+++FVH+R  TV TA  I+E     +T  LFL    A+  +  + + + +N  L +L   G A+HHAG+   DR  VE+ F + HI VLV T+TLAWGVNLPAH VII+GT +Y    G + +L  LDV+Q+FGRAGRPQ+D  GVG +IT+ ++L +YLSLL  Q PIES  ++ LADNLNAEI +GT+ N+ E+I+WL YTYL++RMR NP +YG+E + L  DPTL+   R LI +AA  L+KA M+ F++R+ +    ++GR A+Y+Y   +T++   + +K  M   E+  + S+  EF+ + VR +D++E    L+N    IK   G+E+   K+N L+Q Y+S   ++ F+LSSD +YI+ +  R+ RA+F + L +  A L+ ++L+ CK  E+R W   C L+QF  +  E   KLE++ +   RL D +H EL E + ++     + +  H++P L ++  LQPITR+ +++++ I P F W  + HG + Q FW+++ED  S  I H E F +  K         L   + + +PLPP YYIR  SD W+G  T I + F +++LPE + PLTELL L+ LP   L+N  YES+Y  K + FN IQTQ F  LY++D NV +GAPTGSGKT+ AEIAI R  +     + VY+  L  L + R  +W + F   +LG  V++LTG+   D ++I ++ +IV+T E WD +SR W+ ++ +Q++ L ++D++HL+G +  G  +EVI SRT ++SS     IRI+GLS +L NA+D+  WL  +    YNF PSVR  PL + I  F   H   R+A M++P +Q I   SP  P IVFV + +QT   A  L+ +    S+ K F    E  +   ++NI  + L   L+ G+G  H  L   +R  + ELF ++ IQILV + TL W +   A+LV++  T+ ++GK   Y D    D++QM+GRA     D +  +V++    KK+F +KFL++P P+ES L   L +H NAEIV  T+++KQ A+DYLTWT+ + R+ RNP+YY L+ +   ++++ +S LVE  + +L  + C+  +D   +    LG I+++YY+ Y T++ F   L+P    + +L  I ++ EF+ LP+RH ED     + +  R  P S         TK  +LLQA+ +R  +  ++   D    L  + R++QA VD  +   WL   L   +L Q + QA+W   S    +P  NE                   P L E C+      A  ++  F+  E+E       D  ++A+  F + +            L D  R  +   + N D    V+ + ++  GQ        R      +V+   +P  + E+W+L +G      L+++K +S   ++ +  ++F A  + G  + TLY MSD  +G DQ+Y     ++
Sbjct:  424 QHAGFIGGSRITLPDNAQRIDNKQWEEVKIPASEPPPLSVGNKRVQIEELDDVGRLAFANCKELNRIQSVVFPVAYHSNENMLVCAPTGAGKTNVAMLSIVHTIRCHLE-QGVINRDEFKIVYIAPMKALAAEMVDNFSKRLKSLQIAVRELTGDIQLTKAEMAATQILVTTPEKWDVVTRKGSGDVALISLVELLIIDEVHLLHGERGPVVEALVARTLRLVESSQSMI--RIVGLSATLPNYIDVAHFLRVNPMKGLFYFDSRFRPVPLDTNFVGIKSVKQLQQIADMDQCCYQKCVEMVQEGHQIMVFVHARNATVRTANVIRELAQQNNTSALFLPKDSAAHGLATRSIQRSRNKQLVELFSCGLAMHHAGMLRADRQMVEKYFVEGHISVLVCTATLAWGVNLPAHAVIIRGTDIYDAKHGSFVDLGILDVLQIFGRAGRPQFDKSGVGTIITSYDKLNHYLSLLTNQFPIESNFVNCLADNLNAEIGLGTITNVDEAIEWLSYTYLFVRMRINPHVYGIEYSELEKDPTLEARRRALIMSAAMSLDKARMMRFNQRTMDMNITDLGRTASYFYIKYDTVETFNELMKPFMTQAEILAMISQAQEFQQLKVR-DDEMEELDELKNAYCKIKPYGGSENVHGKVNILIQTYLSNGYVKSFSLSSDMSYITTNIGRISRALFSIVLRQNNAVLSGNMLQLCKMFERRQWDFDCHLKQFPTINAETIDKLERRGLSVYRLRDMEHRELKEWLRSNTYADLVIRSAHELPLLEVEASLQPITRTVLRIKVDIWPSFTWNDRVHGKTCQSFWLWIEDPESNYIYHSELFQVTRKLVMSGQSQQLVMTIPLKEPLPPQYYIRVSSDNWLGSTTCIPLSFQHLVLPEHHPPLTELLPLRPLPVSCLKNVVYESLY--KFTHFNPIQTQIFHCLYHTDNNVLLGAPTGSGKTIVAEIAIFRALNQNPKCKVVYIAPLKALVKERIADWEQRFQRSSLGLKVVELTGDVTPDIQAIRESQLIVTTPEKWDGISRSWQTREYVQHVSLIVIDEIHLLG-EDRGPVIEVIVSRTNFISSHTGRAIRIVGLSTALANAQDLANWLGINKMGLYNFKPSVRPVPLQVHINGFPGKHYCPRMATMNRPTFQAIRTYSPCEPTIVFVSSRRQTRLTALDLITFVAGESNPKQFLHIPEDEIELILQNIREQNLKFCLAFGIGLHHAGLQEQDRKCVEELFLNRKIQILVATATLAWGVNLPAHLVVIKGTEYFDGKVKKYVDMPITDVLQMMGRAGRPQFDNEGVAVVLVHDEKKNFYKKFLYDPFPVESSLLGVLPEHINAEIVAGTVQSKQAALDYLTWTYFFRRLLRNPSYYQLQDIEPENVNNFMSNLVERVVYELSAAACLVERDGCLIPTF-LGRISSYYYLSYRTMKHFLEDLQPGMNTKKVLLAIADSYEFDQLPVRHNEDKHNEEMAEVSRFRPPSSS--WDSSYTKTFLLLQAHFARQSLPNSDYLTDTKSALDNATRVMQAMVDYTAERGWLSTTLVVQQLMQSVIQARWFDGSEFLTLPGVNEDNLDAFLNIPHDDYDYLTLPVLKELCKQEYEVLAKPLRDAFEEHEIEKMYKVIQDLPEIAIQIFVEGRHMENEYAKRPLSLSDDTRGEWMSLHANEDYVLIVNLQRLNVSGQ-------RRGGGQSYTVHCPKYPKPKNEAWFLTLGSQANDELLAMKRVSIRGQRCTNRISFQATPRLGRLQLTLYLMSDCLMGFDQQYDLQFEII 2178

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Fly
Match: DNApol-theta (gene:FBgn0002905 transcript:FBtr0082662)

HSP 1 Score: 107.457 bits (267), Expect = 1.411e-22
Identity = 125/456 (27.41%), Postives = 212/456 (46.49%), Query Frame = 1

Query: 1582 NILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXX-XXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKH-----------------QVLIFVHSRKE----TVNTAKAIKEKCLNRDTLGLFLR---DKKASTLVLQQDLDKVKNHD--LKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQL-PIESQLISKLADNLN---AEIVMGTVRNIHESIDWL 2856
            N++  APT AGKT V+ + M++          T+ +   K++ I P  S+V E      + L     +V    G  +          + +CT EK + I  K  E+   + + ++++DE+HL+    RG +LE ++A+ +    S  + + ++++ +SATL N + +  ++  +       + ++YRPV + +E + +       R++L+ D+  +KV+    ++                  V++F  S+       V  A AI  +  +   LG  LR   + +A   V QQ  D     D  +   + Y  A HHAGL   +R+ +E  F    ++VLV+TSTL+ GVNLPA  V+I+      P  G   ++S+L   QM GRAGR   DT G  I+I NE        L+  +L PI S L    + +L     E++   V N  E ID+ 
Sbjct:  251 NLVYSAPTSAGKTLVSEILMLK----------TVLERGKKVLLILPFISVVREKMFYMQDLLTPAGYRVEGFYG-GYTPPGGFESLHVAICTIEKANSIVNKLMEQGKLETIGMVVVDEVHLISDKGRGYILELLLAKIL--YMSRRNGLQIQVITMSATLENVQLLQSWLDAEL------YITNYRPVAL-KEMIKVGTVIYDHRLKLVRDVAKQKVLLKGLENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQLATAIHVQIKSETVLGQRLRTNLNPRAIAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLTTEERDIIEASFKAGALKVLVATSTLSSGVNLPARRVLIRS-----PLFG-GKQMSSLTYRQMIGRAGRMGKDTLGESILICNEINARMGRDLVVSELQPITSCLDMDGSTHLKRALLEVISSGVANTKEDIDFF 680

HSP 2 Score: 85.1149 bits (209), Expect = 7.781e-16
Identity = 92/441 (20.86%), Postives = 185/441 (41.95%), Query Frame = 1

Query: 4126 NVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQ------------TILKLSPNSPVIVFVPTMKQTEEIAFLL-------------MGYALSDKKNFGRASEAIVSEYMRNIS---NEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMC-QTNKKDFIQKFLHEPLPLESHLDHQLHDHFNA---EIVTKTIENKQDAVDYL 5349
            N+   APT +GKT+ +EI +++    R   + + +     + + +           G  V    G            H+ + T E  + +  +  ++  ++ I + +VD++HLI  +  G  LE++ ++  YMS +    I++I +S +L N + +  WLD     T N+ P      + +    ++      R  A  K + +             I  L     VIVF P+    E +A  L             +G  L  + N    + A V + +R+I    + ++ + ++    F H  L+  ER+++   F + ++++LV + TL   +   A  V++  + ++ GK       S++   QM+GRA     D    S+++C + N +      + E  P+ S LD     H      E+++  + N ++ +D+ 
Sbjct:  251 NLVYSAPTSAGKTLVSEILMLKTVLER-GKKVLLILPFISVVREKMFYMQDLLTPAGYRVEGFYGGYTPPG-GFESLHVAICTIEKANSIVNKLMEQGKLETIGMVVVDEVHLISDKGRGYILELLLAKILYMSRRNGLQIQVITMSATLENVQLLQSWLDAELYIT-NYRPVALKEMIKVGTVIYDHRLKLVRDVAKQKVLLKGLENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQLATAIHVQIKSETVLGQRL--RTNLNPRAIAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLTTEERDIIEASFKAGALKVLVATSTLSSGVNLPARRVLIR-SPLFGGK-----QMSSLTYRQMIGRAGRMGKDTLGESILICNEINARMGRDLVVSELQPITSCLDMDGSTHLKRALLEVISSGVANTKEDIDFF 680

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Fly
Match: mus301 (gene:FBgn0002899 transcript:FBtr0076689)

HSP 1 Score: 98.5969 bits (244), Expect = 5.067e-20
Identity = 115/443 (25.96%), Postives = 183/443 (41.31%), Query Frame = 1

Query: 1564 ALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSE-----------------------RLKSYNLKVAMLSG-----DSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKH-RGLFKFDSSYRPVPMEQ------EYLGINE-------------------RKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDK---VKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENE 2721
            A+   +N++   PT  GKT VA + M+RE+          R+ +  +++I P  S+V E  ++ S                        R K  +L +A +       DS +  +  +E  ++V   ++  +I  K                        RG  LEA + + M        N +++IVG+SAT+ N  +I+ F++ D + RG       +RPV +++      + L IN                     +AVKR +   D +   + E A +H  L+F  SRK   N A  +            F   +++  L L   LDK   + +  L   LPYG A HH+GL   +R ++E  +    + V+  TSTLA GVNLPA  VII+   V +    E+  L+     QM GRAGR      G  I+I    +
Sbjct:  276 AIRQRKNLIYALPTSGGKTLVAEILMLREL--------LCRERN--VLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVV--DELHLIGEKG-----------------------RGATLEAFLTKVM------FLNANIQIVGMSATIGNLSEISSFLNADVYTRG-------FRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRAD--PDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHK----FFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQ----EF--LTLCKYKQMVGRAGRAGLGEAGESILIAQSKD 658

HSP 2 Score: 84.7297 bits (208), Expect = 8.364e-16
Identity = 92/406 (22.66%), Postives = 171/406 (42.12%), Query Frame = 1

Query: 4123 ENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNM--DNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPS-----VRHRPLDIEI----QTF--------NITHNATRLAAMSKP--VYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAI----VSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKD----CMYDDYSAVDLIQMVGRANHASMDDA-RSVIMCQTNKKDFIQKFLHEPL 5250
            +N+    PT  GKT+ AEI ++R    R+    +++     + Q + +        L   V + T             +  + +++ E   VL       +    I L +VD+LHLIG +  G TLE   ++  ++++     I+I+G+S ++ N  ++  +L+     T  F P      ++  P  +EI    QT         ++ +N +     + P  +   I + +P    +VF P+ K  E +A LL       K    R SE +      + M  I + +L +TL  G+ + H  L+ +ER  +   +    + ++  + TL   +   A  VI+     Y G++    C Y         QMVGRA  A + +A  S+++ Q+     + + L  P+
Sbjct:  281 KNLIYALPTSGGKTLVAEILMLRELLCRE-RNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNAN----IQIVGMSATIGNLSEISSFLNA-DVYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAP--YVGQEFLTLCKYK--------QMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPM 670

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Fly
Match: tst (gene:FBgn0039117 transcript:FBtr0334895)

HSP 1 Score: 85.5001 bits (210), Expect = 5.410e-16
Identity = 99/393 (25.19%), Postives = 168/393 (42.75%), Query Frame = 1

Query: 1684 RKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPM----------------------EQEYLGINERKAVKRIELM------------NDLVYEK----------VMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHD--------LKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMI 2706
            ++D  + +Y +P+K+L N+    F +  K     V +++GD  +          ++ T E    +    S+ T   L  ++  +  ++ + ERG V E ++      +   H NI M    LSAT+PNT ++A+++   K R ++   +  RPVP+                      + +YL  N  KAV+R + M            N L  ++           +  +    V+ F  SR    +   A++   LN +      ++K A      Q L K+K  D        LKD L  G  VHH+G+    +  VE LF +  +++L +T T A GVN+PA  V+    + +  D  E   L   + +QM GRAGR  +D  G  I++
Sbjct:  302 KRDLTRTIYTSPIKALSNQKYRDFRKTFKD----VGLITGDLQIE----PTASCLIMTTEILRSMLYCGSDVT-RDLEWVIFDEVHYINNPERGHVWEEVII-----LLPEHVNIIM----LSATVPNTLELADWVGSTKKRKVYVISTLKRPVPLTHFLYTGAGGKSRDDIFLLVDAQGKYLQGNYEKAVERKKEMQGKAKGGGGGPRNHLNAKQEQYTWIGLIDFLRRSNMMPVVAFTLSRNRCDSNLAALQSVDLNTE------KEKGAVQKFFLQCLAKLKPPDRTIPQVLVLKDALERGIGVHHSGILPILKEIVEMLFQNGLVKLLFATETFAMGVNMPARTVVFDSCKKF--DGLEMRNLKPGEYIQMAGRAGRRGHDETGTAIIM 668

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Zebrafish
Match: snrnp200 (small nuclear ribonucleoprotein 200 (U5) [Source:ZFIN;Acc:ZDB-GENE-081105-64])

HSP 1 Score: 2313.11 bits (5993), Expect = 0.000e+0
Identity = 1179/2157 (54.66%), Postives = 1585/2157 (73.48%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXX--XXXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDG-GVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDD----PTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGA-LGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  KMG R  + KP  +EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  + DKER++  ++LLG    DT+Y+ LV+L  K++DY   K   N   N D+T  ++++ + D+EE ++D YGEV+D  SDD  G EAD ++TL  +    G +                     +   + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR+++ MI YCT L  +Q+  E+ KI  +M+ D   +++L  L+  + KEDI+  ER+R+ + R +++  D+E  D +   +  S  +LDL+++TFTQGSH M NK C+LPDGSFRK + GY  V VPA KPKP   +E LV I  LP Y +A FE  K+LNRIQSK++KT +E+DEN+L+CAPTGAGKTNVAL+ M+REIGKHIN DGTI   DFKI+YIAPM+SLV EM  SF +RL SY + V+ L+GD  L +EEIN TQIIVCTPEKWDII+RK  E+TYTQLV+L+IIDEIHLLHD+RGPVLE+++ART+R ++ +    D+R++GLSATLPN ED+A  + VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYD+KG GI+IT+  EL YYLSLLN+QLPIESQ++ KLAD LNAEIV+G V+N  ++++WL YTYLY+RM +NP+LYGV +   DD    P L+    +L++TAA++LEK  ++ +DKRSG F   ++GRIA+++Y T+E++    + LK ++ +IE+F+VFS  +EFRNITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQAYISQLKLE F L +D  Y++QSA RLMRA+FE+ LS+ WA LT   L  CK +++RMW    PLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+HQ PKL+L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE +LH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR  SD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y +   FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+  +  + RCVY+T +  LA+  + +W + F   L K V+ LTG T+ D K + K  IIVST + WD+LSRRWK++K +QN+ LFI+D++HLIG   NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+DV  WL C  TAT+NF+P+VR  PL++ IQ FN++H  TRL +M+KPVY  I+K SP+ PV+VFVP+ +QT   A  ++ +  +D   + F  ++E  +  +M N+S+  L ETLS GVG++HE LS  ER ++  LF+S +IQ++V S +LCW     A+LVIVMDTQ YNGK   Y DY   D++QMVG+AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH LHDHFNAEIVTKT+ENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVENTL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +KVR L+E+I NA E++++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K+VRLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS L+Q+PHF   +L++RC   GV+++FD+ME+EDE +  L+   D ++ DVARF   YPNI+L+YEV     + +G  V VQ+ L R+E+    V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP   G + YTLYFMSD+Y+GCDQEY+F+  V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTKMGDRSQRTKPQMLEERRAKRRKRDEDRHDINKMKGFTLLSEGIDEMVGIVYKPKTKETRETYEILLSFIQAALGDQP-RDILCGAADEVLAVLKNDKMRDKERRREVEQLLGPT-DDTRYHVLVNLGKKISDYGGDKELQNMDDNIDETYGVNVQFESDEEEGDEDQYGEVRDEGSDDSEGEEADESSTLTANLGNTGDVM--------------------MTKKKDLHPRDIDAFWLQRQLSRFYNDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRRMILYCTMLASAQSEAEKEKIINKMEADQDLSKVLYQLQETE-KEDIIREERSRRERMRKSRVD-DLESMDIDHGESVSSRQLLDLEDLTFTQGSHFMANKRCQLPDGSFRKQRKGYEEVHVPALKPKPFGDEETLVGIEKLPKYAQAGFEGFKSLNRIQSKLFKTTMETDENLLVCAPTGAGKTNVALMAMLREIGKHINMDGTINVADFKIIYIAPMRSLVQEMVGSFGKRLASYGIIVSELTGDHQLCKEEINATQIIVCTPEKWDIITRKGGERTYTQLVRLIIIDEIHLLHDDRGPVLESLIARTIRNVELTQE--DVRLIGLSATLPNYEDVATCLRVDPSKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDSKGEGILITSHGELQYYLSLLNQQLPIESQMVGKLADMLNAEIVLGNVQNAKDAVNWLGYTYLYVRMLRNPTLYGVSH---DDRSIDPLLERRRMDLVHTAATVLEKNNLVKYDKRSGSFQVTDLGRIASHFYITHESIMTYNQLLKPTLSEIELFRVFSLSSEFRNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAYISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLSRGWAQLTDKTLNLCKMIDKRMWQSMSPLRQFRKLPEEVIKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHQFPKLDLAVHLQPITRSTLKVELTITPDFQWDDKIHGSSEAFWILVEDVDSEVVLHHEYFLLKAKYAQDEHLVTFFVPVFEPLPPQYFIRIASDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNGAFESLY-QNFPFFNPIQTQVFNAVYNSDDNVFVGAPTGSGKTICAEFAILRMLLHNAEGRCVYITPMEALAEQVFLDWHQKFQENLNKKVVLLTGETSTDLKLLGKGDIIVSTPDKWDILSRRWKQRKNVQNVSLFIIDEVHLIGGD-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSTTATFNFHPNVRPVPLELHIQGFNVSHTQTRLLSMAKPVYHAIMKHSPSKPVLVFVPSRRQTRLTAIDILTFCAADVVPQRFLHSTEKDLVPFMENLSDVTLKETLSNGVGYLHEGLSPTERRIVEHLFTSGAIQVVVASRSLCWGTNISAHLVIVMDTQYYNGKIHAYVDYPIYDVLQMVGKANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTVENKQDAVDYLTWTFLYRRMTQNPNYYNLQGMSHRHLSDHLSELVENTLQDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAVRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLRQLPHFTS-ELIKRCTDKGVESIFDIMEMEDEDRTGLLQLSDVQVADVARFCNRYPNIELSYEVVDKDDIKSGSPVVVQVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDPKSNSLISIKRLTLQQKAKVKLDFVAP-VVGVHNYTLYFMSDAYMGCDQEYKFSTEV 2122

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Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXX--XXXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDG-GVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDD----PTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGA-LGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  KMG R  + KP  +EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  + DKER++  ++LLG    DT+Y+ LV+L  K++DY   K   N   N D+T  ++++ + D+EE ++D YGEV+D  SDD  G EAD ++TL  +    G +                     +   + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR+++ MI YCT L  +Q+  E+ KI  +M+ D   +++L  L+  + KEDI+  ER+R+ + R +++  D+E  D +   +  S  +LDL+++TFTQGSH M NK C+LPDGSFRK + GY  V VPA KPKP   +E LV I  LP Y +A FE  K+LNRIQSK++KT +E+DEN+L+CAPTGAGKTNVAL+ M+REIGKHIN DGTI   DFKI+YIAPM+SLV EM  SF +RL SY + V+ L+GD  L +EEIN TQIIVCTPEKWDII+RK  E+TYTQLV+L+IIDEIHLLHD+RGPVLE+++ART+R ++ +    D+R++GLSATLPN ED+A  + VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYD+KG GI+IT+  EL YYLSLLN+QLPIESQ++ KLAD LNAEIV+G V+N  ++++WL YTYLY+RM +NP+LYGV +   DD    P L+    +L++TAA++LEK  ++ +DKRSG F   ++GRIA+++Y T+E++    + LK ++ +IE+F+VFS  +EFRNITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQAYISQLKLE F L +D  Y++QSA RLMRA+FE+ LS+ WA LT   L  CK +++RMW    PLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+HQ PKL+L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE +LH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR  SD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y +   FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+  +  + RCVY+T +  LA+  + +W + F   L K V+ LTG T+ D K + K  IIVST + WD+LSRRWK++K +QN+ LFI+D++HLIG   NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+DV  WL C  TAT+NF+P+VR  PL++ IQ FN++H  TRL +M+KPVY  I+K SP+ PV+VFVP+ +QT   A  ++ +  +D   + F  ++E  +  +M N+S+  L ETLS GVG++HE LS  ER ++  LF+S +IQ++V S +LCW     A+LVIVMDTQ YNGK   Y DY   D++QMVG+AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH LHDHFNAEIVTKT+ENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVENTL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +KVR L+E+I NA E++++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K+VRLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS L+Q+PHF   +L++RC   GV+++FD+ME+EDE +  L+   D ++ DVARF   YPNI+L+YEV     + +G  V VQ+ L R+E+    V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP   G + YTLYFMSD+Y+GCDQEY+F+  V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTKMGDRSQRTKPQMLEERRAKRRKRDEDRHDINKMKGFTLLSEGIDEMVGIVYKPKTKETRETYEILLSFIQAALGDQP-RDILCGAADEVLAVLKNDKMRDKERRREVEQLLGPT-DDTRYHVLVNLGKKISDYGGDKELQNMDDNIDETYGVNVQFESDEEEGDEDQYGEVRDEGSDDSEGEEADESSTLTANLGNTGDVM--------------------MTKKKDLHPRDIDAFWLQRQLSRFYNDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRRMILYCTMLASAQSEAEKEKIINKMEADQDLSKVLYQLQETE-KEDIIREERSRRERMRKSRVD-DLESMDIDHGESVSSRQLLDLEDLTFTQGSHFMANKRCQLPDGSFRKQRKGYEEVHVPALKPKPFGDEETLVGIEKLPKYAQAGFEGFKSLNRIQSKLFKTTMETDENLLVCAPTGAGKTNVALMAMLREIGKHINMDGTINVADFKIIYIAPMRSLVQEMVGSFGKRLASYGIIVSELTGDHQLCKEEINATQIIVCTPEKWDIITRKGGERTYTQLVRLIIIDEIHLLHDDRGPVLESLIARTIRNVELTQE--DVRLIGLSATLPNYEDVATCLRVDPSKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDSKGEGILITSHGELQYYLSLLNQQLPIESQMVGKLADMLNAEIVLGNVQNAKDAVNWLGYTYLYVRMLRNPTLYGVSH---DDRSIDPLLERRRMDLVHTAATVLEKNNLVKYDKRSGSFQVTDLGRIASHFYITHESIMTYNQLLKPTLSEIELFRVFSLSSEFRNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAYISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLSRGWAQLTDKTLNLCKMIDKRMWQSMSPLRQFRKLPEEVIKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHQFPKLDLAVHLQPITRSTLKVELTITPDFQWDDKIHGSSEAFWILVEDVDSEVVLHHEYFLLKAKYAQDEHLVTFFVPVFEPLPPQYFIRIASDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNGAFESLY-QNFPFFNPIQTQVFNAVYNSDDNVFVGAPTGSGKTICAEFAILRMLLHNAEGRCVYITPMEALAEQVFLDWHQKFQENLNKKVVLLTGETSTDLKLLGKGDIIVSTPDKWDILSRRWKQRKNVQNVSLFIIDEVHLIGGD-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSTTATFNFHPNVRPVPLELHIQGFNVSHTQTRLLSMAKPVYHAIMKHSPSKPVLVFVPSRRQTRLTAIDILTFCAADVVPQRFLHSTEKDLVPFMENLSDVTLKETLSNGVGYLHEGLSPTERRIVEHLFTSGAIQVVVASRSLCWGTNISAHLVIVMDTQYYNGKIHAYVDYPIYDVLQMVGKANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTVENKQDAVDYLTWTFLYRRMTQNPNYYNLQGMSHRHLSDHLSELVENTLQDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAVRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLRQLPHFTS-ELIKRCTDKGVESIFDIMEMEDEDRTGLLQLSDVQVADVARFCNRYPNIELSYEVVDKDDIKSGSPVVVQVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDPKSNSLISIKRLTLQQKAKVKLDFVAP-VVGVHNYTLYFMSDAYMGCDQEYKFSTEV 2122

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Zebrafish
Match: ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:NCBI gene;Acc:100332599])

HSP 1 Score: 1264.98 bits (3272), Expect = 0.000e+0
Identity = 695/1798 (38.65%), Postives = 1071/1798 (59.57%), Query Frame = 1

Query:  841 NIANSEKLNVNDIDAFWLQRTLSKHFTDPN----ECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLV-RMLR--------------------------ENKLMIYYCTKLCCSQTPEERNKI---------------------EAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVM-EYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLID-DPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNV-PVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLLKEK--FKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALS--DKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAI-KDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKL--LERCEAAGVKT 6036
             + ++E+L   + D   L++ + K+  + N      ++ +  + E+L   ++D EL+N+L   +G++ F+++ R+L+                          E+ +  Y C     S+  ++  KI                     E+    DP   R+        ++E  + A R+     R    +    +   +V  +YG       K   F  GS ++      LP+G  R     Y  V +P  +P P+  +E  V +++L    +  F+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI +H+   G IRKD FKIVY+APMK+L  EM N FS+RL+   + V  L+GD  L++ EI  TQ++V TPEKWD+++RKS  +   +Q+V+LLI+DE+HLLH++RGPVLE++VART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+   GLF FDS +RPVP+ Q ++GI     V+++  M ++ YEKV+ +    HQV++FVH+R  TV TA ++ E   NR  L  F  D+ A     ++ + + +N  ++++ P GF +HHAG+   DR+ +E +F+  +++VLV T+TLAWGVNLPAH VIIKGT +Y   +G   +L  LDVMQ+FGRAGRPQ+D  G G +IT  ++L++YL+LL +Q PIESQ    LADNLNAEI +GTV N+ E++ WL YTYLY+RMR NP  YG+ +     DP L+ + + L+  +   L+KA MI FD+R+G F S ++GR A+++Y    T++   +       + +V  + SK  EF  I VR+E+  E++K+L N   +P   G E+   KIN LLQ YIS+ +++ F+L SD +Y++Q+AAR+MRA+FE+ L K+W ++T  +L  CK +++R+W  + PLRQF  +P     ++E KN+  D+L D    E+G ++++  +G  + + +HQIP + L+  +QPITR+ ++V L+ITPDF W  + HGS  + +W++VED ++++I H EYFLL++K     +   + F + I++P+P  YYIRAVSD+W+G E    I F +++LPE++ P TELLDLQ LP  AL N EYES+Y  K + +N IQTQ F +LY++D NV +GAPTGSGKT+ AE+AI R+F+    ++ VY+  L  L + R  +W ++    LG+ V++LTG+   D ++I++A +IV+T E WD +SR W+ +  +Q + + I+D++HL+G +  G  LEVI SRT ++SS     +R++GLS +L NARD+ +WL       +NF PSVR  PL++ IQ F   H   R+A M+KPV+Q I   SP  PV++FV + +QT   A  L+ +  +  D K +    E  +++ +  I    L  TL+ G+G  H  L   +R  + ELF +  IQ+L+ + TL W +   A+LVIV  T+ Y+GK   Y DY   D++QM+GRA     DD  ++VI+    KKDF +KFL+EP P+ES L   L DH NAEI   T+ +KQDA+DY+TWT+ + R+  NP+YYNL  +SH  ++ +LS LVE +L DLE S C+ I +D+  +  +  G I+++YY+ + TI MF   LKP   V  LL                    IL+  K S  + +                    +S +P   ++   D   +L  ++R+ QA +DV+++  WL  AL+   L QMI QA+W  DS L  +PH  + +L    R  + GV+ 
Sbjct:  213 GVYSAEELEQRNTDGSILRQEVEKYLNEGNMVSSSAEELSTSLFEMLASTRSDDELQNELFEFLGLEGFEMISRLLQRRSDIVDALVSIPADSRHHFTSGLRDESNMPTYGCQVTIQSEQEKQMMKIYRKEEKKERKRERRGDDGESSESAFHFDPMELRL--------QREQALLAARSSPVLGRHRDYE---RIRYPHVYDSYGEAT----KTSAFIGGSKML------LPEGIRRDNNKMYEEVEIPPNEPMPIGFEEKAVFVSELDEIGQLVFKGMKRLNRIQSIVFETAYNTNENLLICAPTGAGKTNIAMLTILHEIRQHLQPGGVIRKDQFKIVYVAPMKALAAEMTNYFSKRLEPLGIAVKELTGDMQLTKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQVVRLLILDEVHLLHEDRGPVLESLVARTLRQVESTQSMI--RILGLSATLPNYLDVATFLHVNPFIGLFYFDSRFRPVPLGQSFVGIKTTNKVQQLHDMEEVCYEKVLKQIKAGHQVMVFVHARNSTVRTAMSLIEMAKNRGELSFFQVDQGADYGQCEKQIQRSRNKQMREMFPDGFGIHHAGMLRQDRSLMESMFSRGYLKVLVCTATLAWGVNLPAHAVIIKGTNIYDAKRGTLVDLGILDVMQIFGRAGRPQFDKYGEGTIITTHDKLSHYLTLLTQQNPIESQFQQSLADNLNAEIALGTVTNVDEAVRWLSYTYLYVRMRANPLAYGINHKAYQMDPQLELYRKELVVESGRKLDKARMIRFDERTGYFASTDLGRTASHFYIKYNTIESFNELFNAQNTEADVLSIVSKAEEFEQIKVRDEELEELEKMLCNFCELPASGGVENGYGKINILLQTYISRGEVDSFSLISDLSYVAQNAARIMRALFEMALRKRWPAMTYRLLNLCKVMDKRLWGWAHPLRQFNTLPASALARMEDKNLTIDKLRDMGKDEIGHMLHHVNIGLKVKQCVHQIPAILLESSIQPITRTVLRVRLSITPDFRWNDQVHGSVGEPWWLWVEDPINDHIYHSEYFLLQKKQVVSGEPQQVVFTIPIFEPMPSQYYIRAVSDRWLGSEAVCIINFQHLILPERHPPHTELLDLQPLPITALGNREYESLY--KFTHYNPIQTQIFHTLYHTDTNVLLGAPTGSGKTIAAEMAIFRVFNMYPTSKVVYIAPLKALVRERIEDWKIRIEEKLGRKVVELTGDNTPDMRAIAQADLIVTTPEKWDGVSRSWQNRSYVQKVAILIIDEIHLLG-EDRGPVLEVIVSRTNFISSHTSKTVRVVGLSTALANARDLADWLGIGQVGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMATMNKPVFQAIRTHSPAKPVLIFVSSRRQTRLTALDLIAFLATEDDPKQWLHQDEREMTDIIATIRESNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKIQVLIATSTLAWGVNFPAHLVIVKGTEYYDGKTRRYVDYPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLSVLSDHLNAEIAAGTVTSKQDAMDYITWTYFFRRLVMNPSYYNLDDISHETINKYLSNLVERSLRDLECSYCMEIQQDEQTIEPLTYGRISSYYYLKHQTIRMFKERLKPELPVHELL-------------------AILSVSKHSFLMHLHP------------------VSALP--CSDYGTDTKTVLDNAIRICQAMLDVVANEGWLVSALSLCNLVQMIIQARWLHDSSLLTLPHIQKQELYVFRRWSSRGVRA 1945

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Zebrafish
Match: ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:NCBI gene;Acc:100332599])

HSP 1 Score: 271.166 bits (692), Expect = 2.905e-81
Identity = 145/297 (48.82%), Postives = 211/297 (71.04%), Query Frame = 1

Query: 1378 LPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVM-EYAGKHQVL 2262
            LP+G  R     Y  V +P  +P P+  +E  V +++L    +  F+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI +H+   G IRKD FKIVY+APMK+L  EM N FS+RL+   + V  L+GD  L++ EI  TQ++V TPEKWD+++RKS  +   +Q+V+LLI+DE+HLLH++RGPVLE++VART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+   GLF FDS +RPVP+ Q ++GI     V+++  M ++ YEKV+ +    HQV+
Sbjct:    3 LPEGIRRDNNKMYEEVEIPPNEPMPIGFEEKAVFVSELDEIGQLVFKGMKRLNRIQSIVFETAYNTNENLLICAPTGAGKTNIAMLTILHEIRQHLQPGGVIRKDQFKIVYVAPMKALAAEMTNYFSKRLEPLGIAVKELTGDMQLTKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQVVRLLILDEVHLLHEDRGPVLESLVARTLRQVESTQSMI--RILGLSATLPNYLDVATFLHVNPFIGLFYFDSRFRPVPLGQSFVGIKTTNKVQQLHDMEEVCYEKVLKQIKAGHQVM 297

HSP 2 Score: 115.161 bits (287), Expect = 3.303e-27
Identity = 77/249 (30.92%), Postives = 124/249 (49.80%), Query Frame = 1

Query: 4036 EEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSN--------RQDA-RCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAI-QNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCH-HTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILK 4749
            +E   +  K M   N IQ+  FE+ YN++EN+ I APTG+GKT  A + I+             R+D  + VYV  +  LA      + K    LG  V +LTG+  +    I +  ++V+T E WDV++R+     A+ Q ++L I+D++HL+  +  G  LE + +RT       ++ IRI+GLS +L N  DV  +L  +     + F+   R  PL         T+   +L  M +  Y+ +LK
Sbjct:   41 DEIGQLVFKGMKRLNRIQSIVFETAYNTNENLLICAPTGAGKTNIAMLTILHEIRQHLQPGGVIRKDQFKIVYVAPMKALAAEMTNYFSKRLEPLGIAVKELTGDMQLTKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQVVRLLILDEVHLL-HEDRGPVLESLVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPFIGLFYFDSRFRPVPLGQSFVGIKTTNKVQQLHDMEEVCYEKVLK 288

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Zebrafish
Match: hfm1 (helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-061207-43])

HSP 1 Score: 272.707 bits (696), Expect = 2.417e-74
Identity = 191/668 (28.59%), Postives = 320/668 (47.90%), Query Frame = 1

Query: 4039 EYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNR----QDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNK-SISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYM-------SSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIE--IQTFNITHNATRLA---AMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYA-----LSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRI-----KQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLS--SNRWLGPALAAMELAQMITQAQW 5952
            ++ S++ K   +FN +Q+Q  + +  S++N    APTGSGKTV  E+AI+RL         + R VY+  +  L   +Y  W + FG LG    +LTG+T +D+   I  AH+I +TAE WD ++RRWK    + +I+LF+VD++H++  +  G TLEV+ SR + M       + + +  +R + +S ++ N +DV EWL               HRP+ +   +  F    N        +++  +   I   S   P +VF  T K  ++ A +L   A     +  K+   + + +++   +R++           G+G+ H  + +++R +    F+   + +L  + TL   +   A+LV++  T  Y G  C  ++YS  DL+QM+GRA     D  A +VIM +   KD    FL     +ES L   L +H NAEIV  TI +   A+D++  TFLY R  +NP +Y               EL    L  L +   I + +DI++     G +   Y + + T++ FS+ +     +  L+E+I  A EF D+ LR  E   L  +     + ++R PI    + +D   K N L+QA L  +PI+   L +D  +I   +VR+ +   + L   S       L A+ LA+      W
Sbjct:  233 KFRSVF-KDFPYFNYVQSQALDDVLYSNKNFVACAPTGSGKTVLFELAIVRLLIEASEPWHNVRAVYMAPIKALCSQQYDNWKQKFGPLGLKCKELTGDTEIDDFFEIQDAHLIFTTAEKWDSMTRRWKDNCLLTSIRLFLVDEVHVVKDKTRGATLEVVVSRMKTMHFYRQAINPESKASVRFVAVSATIPNIQDVSEWLSDESGPATCLEMDESHRPVKLRKVVLGFPCGSNQNEFKFDLSLNYKLANIIQTYSDQKPTLVFCSTRKGVQQSASVLAKDARFIMSIDHKQRLVKYANSLLDAKLRDL--------FVYGIGYHHAGMDVSDRKITENAFTVGDLPVLFTTSTLAMGVNMPAHLVVIKSTMHYVGGAC--EEYSEADLLQMIGRAGRPQFDTTATAVIMTRPQTKDKYMHFLSGLDCIESSLHTNLVEHLNAEIVLHTISDVNMALDWIRSTFLYIRALKNPKHY---------------ELCLKNLNSLASFNLITMDEDINIKPTETGKLMARYCVAFDTVKQFSM-VTGTETLPELIEMISKAKEFSDMQLRVNERKTLNTLNKDKNRTTIRFPIEGKIKSND--MKVNCLIQAQLGCIPIQEFGLIQDTGKIFRNAVRVSRYLTEFLCHHSKSNFAAQLNALILAKCFRAKLW 871

HSP 2 Score: 270.396 bits (690), Expect = 1.396e-73
Identity = 215/772 (27.85%), Postives = 377/772 (48.83%), Query Frame = 1

Query: 1471 LVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSRE-EINETQIIVCTPEKWDIISRKSSEKTY-TQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQ------SSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRG-LFKFDSSYRPVPMEQEYLGI---NERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAAS--ILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDI--EVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-----VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTL--SKKWASLTLSVLESCKEVEQRMWACSCPL-RQFKKVPWEITKKLEKKNI-PFDRLIDQKHHELGELVNNH-KMGKTIYKYIHQIPKLNLKIHLQP-ITRSTMKVELTI 3705
            L  ++++P+  ++ F+     N +QS+     L S++N + CAPTG+GKT +  L ++R +      + +    + + VY+AP+K+L ++  +++ ++     LK   L+GD+ +    EI +  +I  T EKWD ++R+  +    T +   L+ +   +    RG  LE +V+R M+ M       +  S   +R V +SAT+PN +D++E++  +       + D S+RPV + +  LG    + +   K    +N  +   +  Y+ +   L+F  +RK    +A       L +D   +   D K   +     L   K   L+DL  YG   HHAG+  +DR   E  FT   + VL +TSTLA GVN+PAH+V+IK T  Y    G   E S  D++QM GRAGRPQ+DT    +++T       Y+  L+    IES L + L ++LNAEIV+ T+ +++ ++DW+R T+LYIR  KNP  Y +             C   + + AS  ++   E IN           E G++ A  YC     D +K+F   +  +   E+ ++ SK  EF ++ +R  ++  +  L ++     +  PI+   +    K+NCL+QA +  + ++ F L  DT  I ++A R+ R + E     SK   +  L+ L   K    ++W  S  + +Q +++   +   L    +  F ++      EL  +VN H   G  I + I ++P+  + +   P  + ST ++  T+
Sbjct:  224 LRSVSEIPAKFRSVFKDFPYFNYVQSQALDDVLYSNKNFVACAPTGSGKTVLFELAIVRLL-----IEASEPWHNVRAVYMAPIKALCSQQYDNWKQKFGPLGLKCKELTGDTEIDDFFEIQDAHLIFTTAEKWDSMTRRWKDNCLLTSIRLFLVDEVHVVKDKTRGATLEVVVSR-MKTMHFYRQAINPESKASVRFVAVSATIPNIQDVSEWLSDESGPATCLEMDESHRPVKLRKVVLGFPCGSNQNEFKFDLSLNYKLANIIQTYSDQKPTLVFCSTRKGVQQSASV-----LAKDARFIMSIDHKQRLVKYANSLLDAK---LRDLFVYGIGYHHAGMDVSDRKITENAFTVGDLPVLFTTSTLAMGVNMPAHLVVIKSTMHYV--GGACEEYSEADLLQMIGRAGRPQFDTTATAVIMTRPQTKDKYMHFLSGLDCIESSLHTNLVEHLNAEIVLHTISDVNMALDWIRSTFLYIRALKNPKHYEL-------------CLKNLNSLASFNLITMDEDINIKP-------TETGKLMA-RYCV--AFDTVKQFSMVTGTETLPELIEMISKAKEFSDMQLRVNERKTLNTLNKDKNRTTIRFPIEGKIKSNDMKVNCLIQAQLGCIPIQEFGLIQDTGKIFRNAVRVSRYLTEFLCHHSKSNFAAQLNALILAKCFRAKLWENSPYISKQLERIGLSLATALVNAGLTTFSKIEQTSPRELELIVNRHPPFGNQIKEAISKLPRCEVSLEQIPRYSPSTAEIVFTV 956

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Xenopus
Match: SNRNP200 (small nuclear ribonucleoprotein, U5 200kDa subunit [Source:NCBI gene;Acc:100145098])

HSP 1 Score: 2184.84 bits (5660), Expect = 0.000e+0
Identity = 1108/2140 (51.78%), Postives = 1517/2140 (70.89%), Query Frame = 1

Query:   88 NSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXX----XXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSK--SVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  +MG +  K KP   EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  L DK+R++   +LLG    DT+Y+ LV+L  K++DY   K   N +         ++  E D+++ +E+       + S+ D  G EA    TL+ +  ++G +                      +  + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR++++MI YCT L  +Q+  E+ +I  +M++DP+ ++ L  L+  + KED++   R  + + R   +  D+E  ++     +    +LDL+++ F QGSH M NK C+LPDGSFR+ + GY  V VPA KPKP  +DE LV +  LP Y ++ FE  KTLNRIQSK++K ALE+DEN+LLCAPT                                                    RL +Y + VA L+GD  L +EEIN TQIIVCTPEKWDII+RK  E+TYTQLV+L+I+DE+HLLHD+RGPVLE++VAR +R ++ +    D+R++GLSATLPN ED+A F+ VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  T++AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG++  DR  VE+LF DKHIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ+++KL D LNAE+V+G V+N  ++++WL YTYLYIRM ++P+LYG+  + L  DP L+    +LI+TAA +L+K  ++ +DK++G F   E+GRIA+++Y TN+++    + LK ++ +IE+F+VFS  +EF+NITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQA+ISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   L  CK +++RMW   CPLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+H  PKL+L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+     + RCVY+T +  LA+  + +W + F   L K V+ LTG T+ D K + K +II+ST E WD+LSRRWK++K +QN+ LFIVD+ HLIG   NG  LEVICSR RY+SSQ+E PIR++ LS SL+NA+DV  WL C  T+T+NF+P+VR  PL++ IQ FNI+H  TRL +M+KPVY  I+K SP  P+IVFVP+ KQT   A  ++    +D  ++ F   +E  ++ Y+  +S+E L ETL  GVG++HE LS  ER ++ +LF++ ++Q++V S +LCW +   A+LVI+MDTQ YNGK   Y DY   D++QMVG AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH LHDHFNAEIVTKT+ENKQDAVDYLTWTFLY RMT+NPNYYNL+GVSHRHLSDHLSELVE+TL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +KVR L+E+I NA E+E +P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+PHF+    ++RC   GV++VFD+ME+EDE +  L+   D ++ DVARF   YPNI+L+YEV++  S+ +GG V V + L R+E+    V A  FP KREE WW+V+G+     LISIK L+     KV L+F AP  +G++ YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    8 NSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQKTKPQMQEERRLKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQP-RDILCGAADEVLAVLKNDRLRDKDRRREVDQLLGQT-DDTRYHVLVNLGKKISDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDIYGEVRDEASDDDMDGDEAVVRCTLSANLASSGELMS--------------------SKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTAGDDRECENQLVLLLGFNTFDFIKVLRQHRMMIMYCTLLASAQSEAEKERIMGKMESDPELSKYLYQLQETE-KEDLIREARGHRDKVRQLNVDMDLENMETEQGEAFAPRQVLDLEDLVFAQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFASDEQLVPVEKLPKYAQSGFEGFKTLNRIQSKLFKAALETDENLLLCAPT----------------------------------------------------RLSTYGITVAELTGDHQLCKEEINATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEVHLLHDDRGPVLESLVARAIRNIEMTQE--DVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTSRAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMSRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVAKLPDMLNAEVVLGHVQNAKDAVNWLGYTYLYIRMLRSPNLYGISHDDLKIDPLLEQRRLDLIHTAALLLDKNNLMKYDKKTGNFQVTELGRIASHFYITNDSIQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLDLSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLVTFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTIYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMEALAEQVFMDWFEKFQDRLYKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNVSLFIVDETHLIGGA-NGPVLEVICSRMRYISSQIERPIRVVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAIVKHSPKKPIIVFVPSRKQTRLTAIDILTTCAADVQRQRFLHCTEKDLAPYLEKLSDETLKETLLNGVGYLHEGLSSLERRIVEQLFNTGAVQVIVASRSLCWGLNIAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGYANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTVENKQDAVDYLTWTFLYRRMTQNPNYYNLQGVSHRHLSDHLSELVEHTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYESIPIRHHEDNLLRQLAQKVPHKLT-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFSSEH-IKRCTEKGVESVFDIMEMEDEDRTELLQLSDSQMADVARFCNRYPNIELSYEVAERDSIRSGGAVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDSKSNSLISIKRLTLQQKAKVKLDFVAP-ATGNHNYTLYFMSDAYMGCDQEYKFSVDV 2065

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Xenopus
Match: gipc1 (GIPC PDZ domain containing family member 1 [Source:Xenbase;Acc:XB-GENE-493927])

HSP 1 Score: 1335.09 bits (3454), Expect = 0.000e+0
Identity = 741/1952 (37.96%), Postives = 1146/1952 (58.71%), Query Frame = 1

Query:  955 ILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIY-----YCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQAD----------------IEMEDSNVISNYGSVDMLD---------------------LKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVM-EYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVEN-VLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLLKEK--FKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALS--DKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAI-KDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE----------------------------PKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVS------------KSVSAGGQVSVQIHLARDEDNI------------------SSVYANNFPYKREESWWLVVGEPNQGHLISIKLLSSPTEK--VSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 6468
            + E+L   K++ EL+N+L  ++G +    + ML + +  I      Y  K+  SQ    RN  E    T P        +++   K+ +    R  K  A+  K   D                + M+  + +SN  ++ +L                      +K   F  G+ L+      LP+G  R+    +  V +P  +P P+  +E  V I DL    +  F+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI ++I   G I+KD FKIVY+APMK+L  EM N FS+RL+   + V  L+GD  LS+ EI  TQ++V TPEKWD+++RKS  +   +QLV+LLI+DE+HLLH++RGPVLE++VART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+   GLF FD  +RPVP+ Q ++GI      +++  + ++ YE V+ E     QV++FVH+R  TV TA A++E   N   +  FL ++       ++ + + +N  L++L P GF++HHAG+   DR+ VE LF+  HI+VLV T+TLAWGVNLPAH VIIKGTQ+Y   +G + +L  LDVMQ+FGRAGRPQ+D  G G +IT  ++L++YL+LL +Q PIESQ +  LADNLNAE+ +GTV N+ E++ WL YTYLY+RMR NP +YG+ + V   DP L+ H   L+  A   L+KA MI F++R+G F S ++GR ++++Y    T++   +       + ++  + SK  EF  I VR+E+  E++ L+ N   + +  G E+   KIN LLQ YI + +++ F+L SD+AY++Q+AAR++RA+FE+ L K+W ++T  +L   K +++R+W  + PLRQF  +P  +  KLE+K +  D+L D +  E+G ++++  +G  + + +HQIP + ++  +QPITR+ ++V L I PDF+W  + HG+  + +WI+VED  +++I H EYFLL++K     +  +L F + I++PLP  YYIRA+SD+W+G E    I F +++LPE++ P TELLDLQ LP  AL +  YE++Y  K + FN +QTQ F +LY++D NV +GAPTGSGKTV AE+AI R+F+    ++ VY+  L  L + R  +W ++    LGK V++LTG+   D ++I++A +IV+T E WD +SR W+ +  +Q + + I+D++HL+G +  G  LEVI SRT ++SS  E  +R++GLS +L NARD+ +WL       +NF PSVR  PL++ IQ F   H   R+A+M+KP +Q I   SP  PV++FV + +QT   A  L+ +  +  D K +    E  +++ +  + +  L  TL+ G+G  H  L   +R  + ELF +  IQ+L+ + TL W +   A+LVIV  T+ Y+GK   Y DY   D++QM+GRA     DD  ++VI+    KKDF +KFL+EP P+ES L   L DH NAEI   TI +KQDA+DY+TWT+ + R+  NP+YYNL+ V H  ++  LS LVE +L+DLE S CI I +D+  +     G IA++YY+ + T+ MF   LK +  V  LL ++ ++ E+ DLP+RH ED + + + + L + ++    +    TK ++LLQA+ SR  +   +   D   +L  ++R+ QA +DV + + WL  AL    L QM+ QA+W  D  L  +P+  +                            P+L+  C   G + +F  +   D Q          ++     F    P ID++  +              +V  G Q    + L  D++ +                  S   A  FP  ++E W+L++GE ++  L+++K +     +  VS+ F  P  +G Y YTLY MSDSYLG DQ+Y   +N+V
Sbjct:  260 LFEMLASTKSNDELQNELFELLGPEGLTFIEMLLQQRQKIVERSLNYDNKMYTSQEQRMRNFGE---NTKPNYG-CQVTVQSEQEKQLMKQYRREEKRNAKREKRLGDDGDISGEGLVGFDPRELRMQREHALSNARTMPILGKERDYWERIKYPHVYDSHAEAMKTSAFIGGAKLL------LPEGIQRENNKIFEEVKIPVSEPMPIGFEEKPVYIKDLDEVGQLVFKGVKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIHQNIE-QGVIKKDAFKIVYVAPMKALAAEMTNYFSKRLEPLGISVKELTGDMQLSKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQLVRLLILDEVHLLHEDRGPVLESLVARTLRQVESTQSMI--RILGLSATLPNYLDVASFLHVNPFIGLFFFDGRFRPVPLGQTFIGIKSTNKTQQLHDVEEVCYENVLKEIKAGRQVMVFVHARNSTVRTAMALRELAKNNGHICYFLPNQGPEYGQAEKQVQRSRNKQLRELFPDGFSIHHAGMLRQDRSLVENLFSQGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGTIITTHDKLSHYLTLLTQQNPIESQFLESLADNLNAEVALGTVTNVEEAVKWLSYTYLYVRMRANPLVYGISHKVYQMDPALEKHREQLVIEAGRKLDKARMIRFEERTGFFSSTDLGRTSSHFYIKYNTIETFNELFDAHKTEGDIVAIVSKAEEFEQIKVRDEEIEELEHLIHNYCELHVAGGVENSYGKINILLQTYIGRGEIDNFSLISDSAYVAQNAARIVRALFEIALRKRWPAMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPSVLSKLEEKKLTIDKLKDMRKDEIGHMLHHVNIGLKVKQCVHQIPSITMEATIQPITRTVLRVRLNINPDFKWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLLQKKQVVTKEPQLLVFTIPIFEPLPSQYYIRAISDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGHSHYEALY--KFTHFNPVQTQIFHTLYHTDSNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERIEDWKVRIEEKLGKKVVELTGDVTPDMRAIAEADLIVTTPEKWDGVSRSWQNRSYVQKVSILIIDEIHLLGDE-RGPVLEVIVSRTNFISSHTEKTVRVVGLSTALANARDLADWLGIGQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALDLIAFLATENDPKQWLNMDEREMNDIIGTLKDSNLKLTLAFGIGMHHAGLHERDRRTVEELFVNCKIQVLIATSTLAWGVNFPAHLVIVKGTEFYDGKTRRYVDYPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLEVLSDHLNAEIAAGTITSKQDAMDYITWTYFFRRLMMNPSYYNLEDVGHESMNKFLSNLVEKSLIDLECSYCIEIAEDNRSIEPQTYGRIASYYYLKHQTVRMFKDRLKSDCSVEDLLSVLSDSEEYADLPVRHNEDQMNSELARHLPIEVNP-HSMDSGHTKTHLLLQAHFSRAMLPCPDYATDTKSVLDNAIRICQAMLDVAAHHGWLVTALNIAHLVQMVVQARWVNDPCLITVPNLEKHHLHLFSKWNQGKRKAISGDFTGPIECLPELIAVC--GGREDIFSSILEHDVQV--------TQISQAWNFVSNLPVIDVSLCIKGWWENESQTLPIHTVPPGTQDKKWMMLHADQEYVLQVNLQRIRTGYRKGRQDSKAIAPKFPKAKDEGWFLILGEVDKRELVALKRIGYVRNRNSVSVAFYTPESTGRYIYTLYLMSDSYLGMDQQYDIYLNIV 2184

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Xenopus
Match: gipc1 (GIPC PDZ domain containing family member 1 [Source:Xenbase;Acc:XB-GENE-493927])

HSP 1 Score: 1332.01 bits (3446), Expect = 0.000e+0
Identity = 736/1935 (38.04%), Postives = 1143/1935 (59.07%), Query Frame = 1

Query:  955 ILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQAD----------------IEMEDSNVISNYGSVDMLD---------------------LKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVM-EYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVEN-VLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLLKEK--FKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALS--DKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAI-KDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE----------------------------PKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKSVSAGGQVSVQIHLARDEDNI------------------SSVYANNFPYKREESWWLVVGEPNQGHLISIKLLSSPTEK--VSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 6468
            + E+L   K++ EL+N+L  ++G +    + ML + +  I         ++    NKI     T P        +++   K+ +    R  K  A+  K   D                + M+  + +SN  ++ +L                      +K   F  G+ L+      LP+G  R+    +  V +P  +P P+  +E  V I DL    +  F+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI ++I   G I+KD FKIVY+APMK+L  EM N FS+RL+   + V  L+GD  LS+ EI  TQ++V TPEKWD+++RKS  +   +QLV+LLI+DE+HLLH++RGPVLE++VART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+   GLF FD  +RPVP+ Q ++GI      +++  + ++ YE V+ E     QV++FVH+R  TV TA A++E   N   +  FL ++       ++ + + +N  L++L P GF++HHAG+   DR+ VE LF+  HI+VLV T+TLAWGVNLPAH VIIKGTQ+Y   +G + +L  LDVMQ+FGRAGRPQ+D  G G +IT  ++L++YL+LL +Q PIESQ +  LADNLNAE+ +GTV N+ E++ WL YTYLY+RMR NP +YG+ + V   DP L+ H   L+  A   L+KA MI F++R+G F S ++GR ++++Y    T++   +       + ++  + SK  EF  I VR+E+  E++ L+ N   + +  G E+   KIN LLQ YI + +++ F+L SD+AY++Q+AAR++RA+FE+ L K+W ++T  +L   K +++R+W  + PLRQF  +P  +  KLE+K +  D+L D +  E+G ++++  +G  + + +HQIP + ++  +QPITR+ ++V L I PDF+W  + HG+  + +WI+VED  +++I H EYFLL++K     +  +L F + I++PLP  YYIRA+SD+W+G E    I F +++LPE++ P TELLDLQ LP  AL +  YE++Y  K + FN +QTQ F +LY++D NV +GAPTGSGKTV AE+AI R+F+    ++ VY+  L  L + R  +W ++    LGK V++LTG+   D ++I++A +IV+T E WD +SR W+ +  +Q + + I+D++HL+G +  G  LEVI SRT ++SS  E  +R++GLS +L NARD+ +WL       +NF PSVR  PL++ IQ F   H   R+A+M+KP +Q I   SP  PV++FV + +QT   A  L+ +  +  D K +    E  +++ +  + +  L  TL+ G+G  H  L   +R  + ELF +  IQ+L+ + TL W +   A+LVIV  T+ Y+GK   Y DY   D++QM+GRA     DD  ++VI+    KKDF +KFL+EP P+ES L   L DH NAEI   TI +KQDA+DY+TWT+ + R+  NP+YYNL+ V H  ++  LS LVE +L+DLE S CI I +D+  +     G IA++YY+ + T+ MF   LK +  V  LL ++ ++ E+ DLP+RH ED + + + + L + ++    +    TK ++LLQA+ SR  +   +   D   +L  ++R+ QA +DV + + WL  AL    L QM+ QA+W  D  L  +P+  +                            P+L+  C   G + +F  +   D  K A     +  + DV+   + +   +       +V  G Q    + L  D++ +                  S   A  FP  ++E W+L++GE ++  L+++K +     +  VS+ F  P  +G Y YTLY MSDSYLG DQ+Y   +N+V
Sbjct:  260 LFEMLASTKSNDELQNELFELLGPEGLTFIEMLLQQRQKI-------VERSLNYDNKINFGENTKPNYG-CQVTVQSEQEKQLMKQYRREEKRNAKREKRLGDDGDISGEGLVGFDPRELRMQREHALSNARTMPILGKERDYWERIKYPHVYDSHAEAMKTSAFIGGAKLL------LPEGIQRENNKIFEEVKIPVSEPMPIGFEEKPVYIKDLDEVGQLVFKGVKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIHQNIE-QGVIKKDAFKIVYVAPMKALAAEMTNYFSKRLEPLGISVKELTGDMQLSKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQLVRLLILDEVHLLHEDRGPVLESLVARTLRQVESTQSMI--RILGLSATLPNYLDVASFLHVNPFIGLFFFDGRFRPVPLGQTFIGIKSTNKTQQLHDVEEVCYENVLKEIKAGRQVMVFVHARNSTVRTAMALRELAKNNGHICYFLPNQGPEYGQAEKQVQRSRNKQLRELFPDGFSIHHAGMLRQDRSLVENLFSQGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGTIITTHDKLSHYLTLLTQQNPIESQFLESLADNLNAEVALGTVTNVEEAVKWLSYTYLYVRMRANPLVYGISHKVYQMDPALEKHREQLVIEAGRKLDKARMIRFEERTGFFSSTDLGRTSSHFYIKYNTIETFNELFDAHKTEGDIVAIVSKAEEFEQIKVRDEEIEELEHLIHNYCELHVAGGVENSYGKINILLQTYIGRGEIDNFSLISDSAYVAQNAARIVRALFEIALRKRWPAMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPSVLSKLEEKKLTIDKLKDMRKDEIGHMLHHVNIGLKVKQCVHQIPSITMEATIQPITRTVLRVRLNINPDFKWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLLQKKQVVTKEPQLLVFTIPIFEPLPSQYYIRAISDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGHSHYEALY--KFTHFNPVQTQIFHTLYHTDSNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERIEDWKVRIEEKLGKKVVELTGDVTPDMRAIAEADLIVTTPEKWDGVSRSWQNRSYVQKVSILIIDEIHLLGDE-RGPVLEVIVSRTNFISSHTEKTVRVVGLSTALANARDLADWLGIGQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALDLIAFLATENDPKQWLNMDEREMNDIIGTLKDSNLKLTLAFGIGMHHAGLHERDRRTVEELFVNCKIQVLIATSTLAWGVNFPAHLVIVKGTEFYDGKTRRYVDYPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLEVLSDHLNAEIAAGTITSKQDAMDYITWTYFFRRLMMNPSYYNLEDVGHESMNKFLSNLVEKSLIDLECSYCIEIAEDNRSIEPQTYGRIASYYYLKHQTVRMFKDRLKSDCSVEDLLSVLSDSEEYADLPVRHNEDQMNSELARHLPIEVNP-HSMDSGHTKTHLLLQAHFSRAMLPCPDYATDTKSVLDNAIRICQAMLDVAAHHGWLVTALNIAHLVQMVVQARWVNDPCLITVPNLEKHHLHLFSKWNQGKRKAISGDFTGPIECLPELIAVC--GGREDIFSSILEHDVTKSAWNFVSNLPVIDVSLCIKGWWENESQTLPIHTVPPGTQDKKWMMLHADQEYVLQVNLQRIRTGYRKGRQDSKAIAPKFPKAKDEGWFLILGEVDKRELVALKRIGYVRNRNSVSVAFYTPESTGRYIYTLYLMSDSYLGMDQQYDIYLNIV 2171

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Xenopus
Match: gipc1 (GIPC PDZ domain containing family member 1 [Source:Xenbase;Acc:XB-GENE-493927])

HSP 1 Score: 1330.08 bits (3441), Expect = 0.000e+0
Identity = 737/1947 (37.85%), Postives = 1143/1947 (58.71%), Query Frame = 1

Query:  955 ILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQAD----------------IEMEDSNVISNYGSVDMLD---------------------LKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVM-EYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVEN-VLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLLKEK--FKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALS--DKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAI-KDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE----------------------------PKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVS------------KSVSAGGQVSVQIHLARDEDNI------------------SSVYANNFPYKREESWWLVVGEPNQGHLISIKLLSSPTEK--VSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 6468
            + E+L   K++ EL+N+L  ++G +    + ML + +  I         ++    NKI     T P        +++   K+ +    R  K  A+  K   D                + M+  + +SN  ++ +L                      +K   F  G+ L+      LP+G  R+    +  V +P  +P P+  +E  V I DL    +  F+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI ++I   G I+KD FKIVY+APMK+L  EM N FS+RL+   + V  L+GD  LS+ EI  TQ++V TPEKWD+++RKS  +   +QLV+LLI+DE+HLLH++RGPVLE++VART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+   GLF FD  +RPVP+ Q ++GI      +++  + ++ YE V+ E     QV++FVH+R  TV TA A++E   N   +  FL ++       ++ + + +N  L++L P GF++HHAG+   DR+ VE LF+  HI+VLV T+TLAWGVNLPAH VIIKGTQ+Y   +G + +L  LDVMQ+FGRAGRPQ+D  G G +IT  ++L++YL+LL +Q PIESQ +  LADNLNAE+ +GTV N+ E++ WL YTYLY+RMR NP +YG+ + V   DP L+ H   L+  A   L+KA MI F++R+G F S ++GR ++++Y    T++   +       + ++  + SK  EF  I VR+E+  E++ L+ N   + +  G E+   KIN LLQ YI + +++ F+L SD+AY++Q+AAR++RA+FE+ L K+W ++T  +L   K +++R+W  + PLRQF  +P  +  KLE+K +  D+L D +  E+G ++++  +G  + + +HQIP + ++  +QPITR+ ++V L I PDF+W  + HG+  + +WI+VED  +++I H EYFLL++K     +  +L F + I++PLP  YYIRA+SD+W+G E    I F +++LPE++ P TELLDLQ LP  AL +  YE++Y  K + FN +QTQ F +LY++D NV +GAPTGSGKTV AE+AI R+F+    ++ VY+  L  L + R  +W ++    LGK V++LTG+   D ++I++A +IV+T E WD +SR W+ +  +Q + + I+D++HL+G +  G  LEVI SRT ++SS  E  +R++GLS +L NARD+ +WL       +NF PSVR  PL++ IQ F   H   R+A+M+KP +Q I   SP  PV++FV + +QT   A  L+ +  +  D K +    E  +++ +  + +  L  TL+ G+G  H  L   +R  + ELF +  IQ+L+ + TL W +   A+LVIV  T+ Y+GK   Y DY   D++QM+GRA     DD  ++VI+    KKDF +KFL+EP P+ES L   L DH NAEI   TI +KQDA+DY+TWT+ + R+  NP+YYNL+ V H  ++  LS LVE +L+DLE S CI I +D+  +     G IA++YY+ + T+ MF   LK +  V  LL ++ ++ E+ DLP+RH ED + + + + L + ++    +    TK ++LLQA+ SR  +   +   D   +L  ++R+ QA +DV + + WL  AL    L QM+ QA+W  D  L  +P+  +                            P+L+  C   G + +F  +   D Q          ++     F    P ID++  +              +V  G Q    + L  D++ +                  S   A  FP  ++E W+L++GE ++  L+++K +     +  VS+ F  P  +G Y YTLY MSDSYLG DQ+Y   +N+V
Sbjct:   52 LFEMLASTKSNDELQNELFELLGPEGLTFIEMLLQQRQKI-------VERSLNYDNKINFGENTKPNYG-CQVTVQSEQEKQLMKQYRREEKRNAKREKRLGDDGDISGEGLVGFDPRELRMQREHALSNARTMPILGKERDYWERIKYPHVYDSHAEAMKTSAFIGGAKLL------LPEGIQRENNKIFEEVKIPVSEPMPIGFEEKPVYIKDLDEVGQLVFKGVKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIHQNIE-QGVIKKDAFKIVYVAPMKALAAEMTNYFSKRLEPLGISVKELTGDMQLSKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQLVRLLILDEVHLLHEDRGPVLESLVARTLRQVESTQSMI--RILGLSATLPNYLDVASFLHVNPFIGLFFFDGRFRPVPLGQTFIGIKSTNKTQQLHDVEEVCYENVLKEIKAGRQVMVFVHARNSTVRTAMALRELAKNNGHICYFLPNQGPEYGQAEKQVQRSRNKQLRELFPDGFSIHHAGMLRQDRSLVENLFSQGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGTIITTHDKLSHYLTLLTQQNPIESQFLESLADNLNAEVALGTVTNVEEAVKWLSYTYLYVRMRANPLVYGISHKVYQMDPALEKHREQLVIEAGRKLDKARMIRFEERTGFFSSTDLGRTSSHFYIKYNTIETFNELFDAHKTEGDIVAIVSKAEEFEQIKVRDEEIEELEHLIHNYCELHVAGGVENSYGKINILLQTYIGRGEIDNFSLISDSAYVAQNAARIVRALFEIALRKRWPAMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPSVLSKLEEKKLTIDKLKDMRKDEIGHMLHHVNIGLKVKQCVHQIPSITMEATIQPITRTVLRVRLNINPDFKWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLLQKKQVVTKEPQLLVFTIPIFEPLPSQYYIRAISDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGHSHYEALY--KFTHFNPVQTQIFHTLYHTDSNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERIEDWKVRIEEKLGKKVVELTGDVTPDMRAIAEADLIVTTPEKWDGVSRSWQNRSYVQKVSILIIDEIHLLGDE-RGPVLEVIVSRTNFISSHTEKTVRVVGLSTALANARDLADWLGIGQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALDLIAFLATENDPKQWLNMDEREMNDIIGTLKDSNLKLTLAFGIGMHHAGLHERDRRTVEELFVNCKIQVLIATSTLAWGVNFPAHLVIVKGTEFYDGKTRRYVDYPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLEVLSDHLNAEIAAGTITSKQDAMDYITWTYFFRRLMMNPSYYNLEDVGHESMNKFLSNLVEKSLIDLECSYCIEIAEDNRSIEPQTYGRIASYYYLKHQTVRMFKDRLKSDCSVEDLLSVLSDSEEYADLPVRHNEDQMNSELARHLPIEVNP-HSMDSGHTKTHLLLQAHFSRAMLPCPDYATDTKSVLDNAIRICQAMLDVAAHHGWLVTALNIAHLVQMVVQARWVNDPCLITVPNLEKHHLHLFSKWNQGKRKAISGDFTGPIECLPELIAVC--GGREDIFSSILEHDVQV--------TQISQAWNFVSNLPVIDVSLCIKGWWENESQTLPIHTVPPGTQDKKWMMLHADQEYVLQVNLQRIRTGYRKGRQDSKAIAPKFPKAKDEGWFLILGEVDKRELVALKRIGYVRNRNSVSVAFYTPESTGRYIYTLYLMSDSYLGMDQQYDIYLNIV 1967

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Xenopus
Match: gipc1 (GIPC PDZ domain containing family member 1 [Source:Xenbase;Acc:XB-GENE-493927])

HSP 1 Score: 1316.6 bits (3406), Expect = 0.000e+0
Identity = 736/1932 (38.10%), Postives = 1135/1932 (58.75%), Query Frame = 1

Query:  955 ILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQAD----------------IEMEDSNVISNYGSVDMLD---------------------LKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVEN-VLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLLKEK--FKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALS--DKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAI-KDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKL-LERCEAAGVKTVFDLMELEDEQKLALMNFPDD-------------KLQDVARFFQCYPNIDLTYEVS------------KSVSAGGQVSVQIHLARDEDNI------------------SSVYANNFPYKREESWWLVVGEPNQGHLISIKLLSSPTEK--VSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 6468
            + E+L   K++ EL+N+L  ++G +    + ML + +  I         ++    NKI     T P        +++   K+ +    R  K  A+  K   D                + M+  + +SN  ++ +L                      +K   F  G+ L+      LP+G  R+    +  V +P  +P P+  +E  V I DL    +  F+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI ++I   G I+KD FKIVY+APMK+L  EM N FS+RL+   + V  L+GD  LS+ EI  TQ++V TPEKWD+++RKS  +   +QLV+LLI+DE+HLLH++RGPVLE++VART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+   GLF FD  +RPVP+ Q ++GI           MN   +           V++FVH+R  TV TA A++E   N   +  FL ++       ++ + + +N  L++L P GF++HHAG+   DR+ VE LF+  HI+VLV T+TLAWGVNLPAH VIIKGTQ+Y   +G + +L  LDVMQ+FGRAGRPQ+D  G G +IT  ++L++YL+LL +Q PIESQ +  LADNLNAE+ +GTV N+ E++ WL YTYLY+RMR NP +YG+ + V   DP L+ H   L+  A   L+KA MI F++R+G F S ++GR ++++Y    T++   +       + ++  + SK  EF  I VR+E+  E++ L+ N   + +  G E+   KIN LLQ YI + +++ F+L SD+AY++Q+AAR++RA+FE+ L K+W ++T  +L   K +++R+W  + PLRQF  +P  +  KLE+K +  D+L D +  E+G ++++  +G  + + +HQIP + ++  +QPITR+ ++V L I PDF+W  + HG+  + +WI+VED  +++I H EYFLL++K     +  +L F + I++PLP  YYIRA+SD+W+G E    I F +++LPE++ P TELLDLQ LP  AL +  YE++Y  K + FN +QTQ F +LY++D NV +GAPTGSGKTV AE+AI R+F+    ++ VY+  L  L + R  +W ++    LGK V++LTG+   D ++I++A +IV+T E WD +SR W+ +  +Q + + I+D++HL+G +  G  LEVI SRT ++SS  E  +R++GLS +L NARD+ +WL       +NF PSVR  PL++ IQ F   H   R+A+M+KP +Q I   SP  PV++FV + +QT   A  L+ +  +  D K +    E  +++ +  + +  L  TL+ G+G  H  L   +R  + ELF +  IQ+L+ + TL W +   A+LVIV  T+ Y+GK   Y DY   D++QM+GRA     DD  ++VI+    KKDF +KFL+EP P+ES L   L DH NAEI   TI +KQDA+DY+TWT+ + R+  NP+YYNL+ V H  ++  LS LVE +L+DLE S CI I +D+  +     G IA++YY+ + T+ MF   LK +  V  LL ++ ++ E+ DLP+RH ED + + + + L + ++    +    TK ++LLQA+ SR  +   +   D   +L  ++R+ QA +DV + + WL  AL    L QM+ QA+W  D  L  +P+  +  L L RC  A        +E   E  +A+    +D             ++     F    P ID++  +              +V  G Q    + L  D++ +                  S   A  FP  ++E W+L++GE ++  L+++K +     +  VS+ F  P  +G Y YTLY MSDSYLG DQ+Y   +N+V
Sbjct:  260 LFEMLASTKSNDELQNELFELLGPEGLTFIEMLLQQRQKI-------VERSLNYDNKINFGENTKPNYG-CQVTVQSEQEKQLMKQYRREEKRNAKREKRLGDDGDISGEGLVGFDPRELRMQREHALSNARTMPILGKERDYWERIKYPHVYDSHAEAMKTSAFIGGAKLL------LPEGIQRENNKIFEEVKIPVSEPMPIGFEEKPVYIKDLDEVGQLVFKGVKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIHQNIE-QGVIKKDAFKIVYVAPMKALAAEMTNYFSKRLEPLGISVKELTGDMQLSKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQLVRLLILDEVHLLHEDRGPVLESLVARTLRQVESTQSMI--RILGLSATLPNYLDVASFLHVNPFIGLFFFDGRFRPVPLGQTFIGIKSTNKAS----MNLKAF----------CVMVFVHARNSTVRTAMALRELAKNNGHICYFLPNQGPEYGQAEKQVQRSRNKQLRELFPDGFSIHHAGMLRQDRSLVENLFSQGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGTIITTHDKLSHYLTLLTQQNPIESQFLESLADNLNAEVALGTVTNVEEAVKWLSYTYLYVRMRANPLVYGISHKVYQMDPALEKHREQLVIEAGRKLDKARMIRFEERTGFFSSTDLGRTSSHFYIKYNTIETFNELFDAHKTEGDIVAIVSKAEEFEQIKVRDEEIEELEHLIHNYCELHVAGGVENSYGKINILLQTYIGRGEIDNFSLISDSAYVAQNAARIVRALFEIALRKRWPAMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPSVLSKLEEKKLTIDKLKDMRKDEIGHMLHHVNIGLKVKQCVHQIPSITMEATIQPITRTVLRVRLNINPDFKWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLLQKKQVVTKEPQLLVFTIPIFEPLPSQYYIRAISDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGHSHYEALY--KFTHFNPVQTQIFHTLYHTDSNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERIEDWKVRIEEKLGKKVVELTGDVTPDMRAIAEADLIVTTPEKWDGVSRSWQNRSYVQKVSILIIDEIHLLGDE-RGPVLEVIVSRTNFISSHTEKTVRVVGLSTALANARDLADWLGIGQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALDLIAFLATENDPKQWLNMDEREMNDIIGTLKDSNLKLTLAFGIGMHHAGLHERDRRTVEELFVNCKIQVLIATSTLAWGVNFPAHLVIVKGTEFYDGKTRRYVDYPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLEVLSDHLNAEIAAGTITSKQDAMDYITWTYFFRRLMMNPSYYNLEDVGHESMNKFLSNLVEKSLIDLECSYCIEIAEDNRSIEPQTYGRIASYYYLKHQTVRMFKDRLKSDCSVEDLLSVLSDSEEYADLPVRHNEDQMNSELARHLPIEVNP-HSMDSGHTKTHLLLQAHFSRAMLPCPDYATDTKSVLDNAIRICQAMLDVAAHHGWLVTALNIAHLVQMVVQARWVNDPCLITVPNLEKHHLHLFRCRKAISGDFTGPIECLPEL-IAVCGGREDIFSSILEHDVQVTQISQAWNFVSNLPVIDVSLCIKGWWENESQTLPIHTVPPGTQDKKWMMLHADQEYVLQVNLQRIRTGYRKGRQDSKAIAPKFPKAKDEGWFLILGEVDKRELVALKRIGYVRNRNSVSVAFYTPESTGRYIYTLYLMSDSYLGMDQQYDIYLNIV 2155

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Mouse
Match: Snrnp200 (small nuclear ribonucleoprotein 200 (U5) [Source:MGI Symbol;Acc:MGI:2444401])

HSP 1 Score: 2325.44 bits (6025), Expect = 0.000e+0
Identity = 1171/2156 (54.31%), Postives = 1569/2156 (72.77%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXX----XXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISN-YGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  +MG +  + KP   EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  L DKER++    LLG    DT+Y+ LV+L  K+TDY   K   N +         ++  E D+++ +E+       + S+ D  G EA    TL+ +  A+G +                      +  + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR++++MI YCT L  +Q+  E+ +I  +M+ DP+ ++ L  L   + KED++  ER+R+ + R +++  D+E  D +          +LDL+++ FTQGSH M NK C+LPDGSFR+ + GY  V VPA KPKP  ++E L+ +  LP Y +A FE  KTLNRIQSK+Y+ ALE+DEN+LLCAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SF +RL +Y + VA L+GD  L +EEI+ TQIIVCTPEKWDII+RK  E+TYTQLV+L+++DEIHLLHD+RGPVLEA+VAR +R ++ +    D+R++GLSATLPN ED+A F+ VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF DKHIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ++SKL D LNAEIV+G V+N  ++++WL Y YLYIRM ++P+LYG+  + L  DP LD    +L++TAA +L+K  ++ +DK++G F   E+GRIA++YY TN+T+    + LK ++ +IE+F+VFS  +EF+NITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQA+ISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   L  CK +++RMW   CPLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+H  PKL L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+     + RCVY+T +  LA+  Y +W + F   L K V+ LTG T+ D K + K +II+ST E WD+LSRRWK++K +QNI LF+VD++HLIG + NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+DV  WL C  T+T+NF+P+VR  PL++ IQ FNI+H  TRL +M+KPVY  I K SP  PVIVFVP+ KQT   A  ++    +D  ++ F   +E  +  Y+  +S+  L ETL  GVG++HE LS  ER L+ +LFSS +IQ++V S +LCW +   A+LVI+MDTQ YNGK   Y DY   D++QMVG AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH +HDHFNAEIVTKTIENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVE TL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +KVR L+E+I NA E+E++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+PHF     ++RC   GV++VFD+ME+EDE++ AL+   D ++ DVARF   YPNI+L+YEV    S+ +GG V V + L R+E+    V A  FP KREE WW+V+G+     LISIK L+     KV L+F AP  +G + YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDMNKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQP-RDILCGAADEVLAVLKNEKLRDKERRREIDLLLGQT-DDTRYHVLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMS--------------------SKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEPEKERIVGKMEADPELSKFLYQLHETE-KEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQE--DVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEH-IKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAP-ATGGHNYTLYFMSDAYMGCDQEYKFSVDV 2126

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Mouse
Match: Ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:MGI Symbol;Acc:MGI:1925237])

HSP 1 Score: 1337.78 bits (3461), Expect = 0.000e+0
Identity = 762/1978 (38.52%), Postives = 1162/1978 (58.75%), Query Frame = 1

Query:  889 WLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMI------------YYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKT----------------------------QARSAKI---QADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVM-EYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLID-DPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFL-LKEKFKNDD-HILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALS--DKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAI-KDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE---------------------------PKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKS----VSAGGQVSVQIHLA--RDEDNISSVYANN----------------------------FPYKREESWWLVVGEPNQGHLISIKLLS--SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 6468
            +L  TL K  T+    +     + ++L  AK+  EL+++L  ++G +  DL+  L +N++ I            +   +  C +   E +K     +   +S +    ++   R+E  + A R +K                              AR+A I   Q D+E E       Y S      +   F  G+ ++      LP+G  R+    Y  V +P  +P P+  +E  V I DL    + AF+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI +H +  G I+K++FKIVY+APMK+L  EM N FS+RL+   + V  L+GD  LS+ EI  TQ++V TPEKWD+++RKS  +   +Q+VKLLI+DE+HLLH++RGPVLE+IVART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+ + GLF FD  +RPVP+ Q +LGI     ++++  M+++ YE V+ +    HQV++FVH+R  TV TA ++ E+  N   +  FL  +        + + K +N  +++L   GF++HHAG+   DRN VE LF++ HI+VLV T+TLAWGVNLPAH V+IKGTQ+Y   +G + +L  LDVMQ+FGRAGRPQ+D  G GI+IT  ++L++YLSLL +Q PIESQ +  LADNLNAEI +GTV N+ E++ W+ YTYLY+RMR NP  YG+ +     DPTL  H   L+      L+KA+MI F++R+G F S ++GR A+++Y    T++   +       + ++F + SK  EF  I VREE+  E+  LL N   +    G E+   KIN LLQ YIS+ +++ F+L SD+AY++Q+AAR++RA+FE+ L K+W ++T  +L   K +++R+W  + PLRQF  +P  I  +LE+KN+  D+L D +  E+G ++++  +G  + + +HQIP + ++  +QPITR+ ++V L I PDF W  + HG+  + +WI+VED  +++I H EYFL LK++  N +  +L F + I++PLP  YYIRAVSD+W+G E    I F +++LPE++ P TELLDLQ LP  AL  + YE++Y+   S FN +QTQ F +LY++D NV +GAPTGSGKTV AE+AI R+F+    ++ VY+  L  L + R  +W ++    LGK VI+LTG+   D KSI+KA +IV+T E WD +SR W+ +  +Q + + I+D++HL+G +  G  LEVI SRT ++SS  E P+RI+GLS +L NARD+ +WL+      +NF PSVR  PL++ IQ F   H   R+A+M+KP +Q I   SP  PV++FV + +QT   A  L+ +  +  D K +    E  +   +  + +  L  TL+ G+G  H  L   +R  + ELF +  +Q+L+ + TL W +   A+LVI+  T+ Y+GK   Y D+   D++QM+GRA     DD  ++VI+    KKDF +KFL+EP P+ES L   L DH NAEI   TI +KQDA+DY+TWT+ + R+  NP+YY+L  VS   ++  LS L+  +L++LE S CI + +D+  +  +  G IA++YY+ + T++MF   LKP      LL ++ +A E+ DLP+RH ED     + + L + ++       P TKA++LLQA+LSR  +   +   D   +L +++R+ QA +DV +S  WL   L    L QM+ Q +W +DS L  IP+  +                           P+L+  CE  G   VF  M +E E + A       K +    F    P I++   V  S    V    ++S+    A  RDE+    ++A+                             FP  ++E W+L++GE ++  L+++K +         S++F  P   G Y +TLY MSD YLG DQ+Y   +NV+
Sbjct:  230 YLNATL-KEMTEAARVEDLCCTLYDMLASAKSGDELQDELFELLGPEGLDLIEKLLQNRITIVDRFLNSSSDHKFQVLQDSCKKILGENSKPNYGCQVTIQSEQEKQLMKQYRREEKRI-ARREKKAGEDGEVSGEGVLPFDPKELRIQREHALLNARNAPILGRQRDVEFEKIRYPHVYDS-QAQARETSAFIAGAKMI------LPEGIQRENTKLYEEVRIPYGEPMPVGFEEKPVYIKDLDEVGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTILHEIRQHFH-QGVIKKNEFKIVYVAPMKALAAEMTNYFSKRLEPLGIVVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVKLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMI--RILGLSATLPNYLDVATFLHVNPYIGLFYFDGRFRPVPLGQTFLGIKSTNKMQQLNNMDEVCYESVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNSGQISCFLPTEGPEYGHALKQVQKSRNKQVRELFSDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVVIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLSLLTQQNPIESQFLESLADNLNAEIALGTVTNVEEAVRWMSYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLLIEVGQKLDKAKMIRFEERTGYFSSTDLGRTASHFYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDALLNNFCELSAPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPHILTRLEEKNLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVTMEASIQPITRTVLRVSLNIHPDFSWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVINKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYN--FSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKIRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRSYVQQVNILIIDEIHLLGEE-RGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEQEMDNIIGTVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDAMDYITWTYFFRRLIMNPSYYSLGDVSQDSINKFLSHLIGQSLVELELSHCIEVGEDNRTIEPLTCGRIASYYYLKHKTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHTNNELAKCLPIELNP-HSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAASQGWLVTVLNITHLIQMVIQGRWLKDSSLLTIPNIEQHHLHLFRKWKPPVKSSHAKCRTSIECLPELIHACE--GKDHVFSSM-VEKELQPA-------KTKQAWNFLSRLPVINVGISVKGSWDDLVEGHNELSISTLTADKRDENKWIKLHADQEYVLQVSLQRVHFGLPKGKHENHAVTPRFPKLKDEGWFLILGEVDKRELMAVKRVGFVRTHHDASISFFTPETPGRYIFTLYLMSDCYLGLDQQYDIYLNVI 2181

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Mouse
Match: Hfm1 (HFM1, ATP-dependent DNA helicase homolog [Source:MGI Symbol;Acc:MGI:3036246])

HSP 1 Score: 340.117 bits (871), Expect = 1.271e-94
Identity = 254/815 (31.17%), Postives = 422/815 (51.78%), Query Frame = 1

Query: 1468 NLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSRE-EINETQIIVCTPEKWDIISRKSSEKTYTQLVKX-XXXXXXXXXXXXRGPVLEAIVARTMRAMQS------SHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGL-FKFDSSYRPVPMEQEYLGI---NERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGD--IEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-----VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAM--FEVTLSKKWASLTLSVLESCKEVEQRMWACSCPL-RQFKKVPWEITKKLEKKNI-PFDRLIDQKHHELGELVNNH-KMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTIT---------------PDFEWCPKSHGSSQGFWIFVEDVMSENIL 3795
            +L  + ++P+  +  F++    N IQSK +   L +D N ++CAPTG+GKT V  L + R +      +  +   + KIVY+AP+K+L ++  + + E+     L    L+GD+ +    EI    II+ TPEKWD ++RK  + ++ QLV+L LI +   +  + RGP LE +V+R M+ +QS      S S + +R V +SAT+PN EDIAE++   +   +  K D S+RPV +++  LG    + +   K    +N  VY  +  Y+ +   L+F  +RK     A       L +D   +   ++K   L LQ+    +++  LKD L YG   HHAG+  +DR  VE LFT   + VL +TSTLA G+N+PAH+V+IK T  Y    G + E S  D++QM GRAGRPQ+DT    +++T  +    Y+ +L     +ES L   L ++LNAEIV+ T+ +++ ++DW+R T LYIR  KNPS YG  + L  D  ++   + L       L   ++I  D+    F   E GR+ A+YY T ET   +KKF   S  +  +++  + S C EF ++ +R  +K  +  L ++     +  P+ E  +    K+NCL+QA +  + ++ F L+ DT  I ++ +R+ R +  F     KK+A L  SV+ + K  + ++W  S  + +Q  K+   ++  +    +  F ++ +    EL  ++N H   G  I + +  +PK  L++  Q    S +K E+ +T               PDF +     G +    +F   +M   +L
Sbjct:  259 SLKAVTEIPAKFRNIFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLL-----MEVPLPWLNMKIVYMAPIKALCSQRFDDWKEKFGPVGLNCKELTGDTVMDDLFEIQHANIIITTPEKWDSVTRKWRDNSFIQLVRLFLIDEVHVIKDENRGPTLEVVVSR-MKTVQSLSRDLESASPVPVRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSSQTEFKFDLALNYKVYSVIRTYSDQKPTLVFCSTRKGVQQAASV-----LVKDAKFIISVEQK---LRLQKSAYSIRDSKLKDTLVYGVGYHHAGMELSDRKLVEGLFTSGDLPVLFTTSTLAMGMNMPAHLVVIKSTMHY--SGGVFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTREKYVQMLACNDTVESSLHRHLIEHLNAEIVLHTITDVNIALDWIRSTMLYIRALKNPSHYGFSSGLNKD-GIEAKLQELCLKNLKDLSSLDLIKMDEDVN-FKPTEAGRLMAWYYITFET---VKKFCAISGKETLLDLISMISSCNEFLDVQLRISEKRILNTLNKDPNRITIRFPMAERIKTREMKVNCLIQAQLGCIPIQDFALTQDTVKIFRNGSRIARWLSDFVAAQEKKFAVLLNSVILT-KCFKCKLWENSKHVSKQLDKIGISLSNTMVNAGLTSFKKIEEANARELELILNRHPPFGTQIKEAVAHLPKYELEVE-QIARYSDIKAEILVTIILRNFEQLQTKRTAPDFHYATLIIGDADNQVVFKHKIMDSVLL 1050

HSP 2 Score: 297.36 bits (760), Expect = 5.560e-81
Identity = 196/646 (30.34%), Postives = 330/646 (51.08%), Query Frame = 1

Query: 4060 KKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQ----DARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNK-SISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSR-------TRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIE--IQTFNITHNATRLA---AMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAI-VSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNL-KGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQ-----SLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAME 5922
            K+  +FN IQ++ F+ L  +D N  I APTGSGKTV  E+AI RL         + + VY+  +  L   R+ +W + FG +G    +LTG+T MD+   I  A+II++T E WD ++R+W+    IQ ++LF++D++H+I  ++ G TLEV+ SR       +R + S    P+R + +S ++ NA D+ EWL               HRP+ ++  +  F  + + T      A++  VY  I   S   P +VF  T K  ++ A +L    + D K      + + + +   +I +  L +TL  GVG+ H  + +++R L+  LF+S  + +L  + TL   +   A+LV++  T  Y+G   ++++YS  D++QM+GRA     D  A +VIM + + ++   + L     +ES L   L +H NAEIV  TI +   A+D++  T LY R  +NP++Y    G++   +   L EL    L DL +   I + +D++      G +  +YYI + T++ F  ++     +  L+ +I +  EF D+ LR  E  IL  + +     ++R P++E  R+     K N L+QA L  +PI+   L +D  +I     R+           RWL   +AA E
Sbjct:  275 KEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNMKIVYMAPIKALCSQRFDDWKEKFGPVGLNCKELTGDTVMDDLFEIQHANIIITTPEKWDSVTRKWRDNSFIQLVRLFLIDEVHVIKDENRGPTLEVVVSRMKTVQSLSRDLESASPVPVRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSSQTEFKFDLALNYKVYSVIRTYSDQKPTLVFCSTRKGVQQAASVL----VKDAKFIISVEQKLRLQKSAYSIRDSKLKDTLVYGVGYHHAGMELSDRKLVEGLFTSGDLPVLFTTSTLAMGMNMPAHLVVIKSTMHYSGG--VFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTREKYVQMLACNDTVESSLHRHLIEHLNAEIVLHTITDVNIALDWIRSTMLYIRALKNPSHYGFSSGLNKDGIEAKLQELCLKNLKDLSSLDLIKMDEDVNFKPTEAGRLMAWYYITFETVKKF-CAISGKETLLDLISMISSCNEFLDVQLRISEKRILNTLNKDPNRITIRFPMAE--RIKTREMKVNCLIQAQLGCIPIQDFALTQDTVKIFRNGSRIA----------RWLSDFVAAQE 901

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Query: 1468 NLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSRE-EINETQIIVCTPEKWDIISRKSSEKTYTQLVKX-XXXXXXXXXXXXRGPVLEAIVARTMRAMQS------SHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGL-FKFDSSYRPVPMEQEYLGI---NERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGD--IEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-----VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAM--FEVTLSKKWASLTLSVLESCKEVEQRMWACSCPL-RQFKKVPWEITKKLEKKNI-PFDRLIDQKHHELGELVNNH-KMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTIT---------------PDFEWCPKSHGSSQGFWIFVEDVMSENIL 3795
            +L  + ++P+  +  F++    N IQSK +   L +D N ++CAPTG+GKT V  L + R +      +  +   + KIVY+AP+K+L ++  + + E+     L    L+GD+ +    EI    II+ TPEKWD ++RK  + ++ QLV+L LI +   +  + RGP LE +V+R M+ +QS      S S + +R V +SAT+PN EDIAE++   +   +  K D S+RPV +++  LG    + +   K    +N  VY  +  Y+ +   L+F  +RK     A       L +D   +   ++K   L LQ+    +++  LKD L YG   HHAG+  +DR  VE LFT   + VL +TSTLA G+N+PAH+V+IK T  Y    G + E S  D++QM GRAGRPQ+DT    +++T  +    Y+ +L     +ES L   L ++LNAEIV+ T+ +++ ++DW+R T LYIR  KNPS YG  + L  D  ++   + L       L   ++I  D+    F   E GR+ A+YY T ET   +KKF   S  +  +++  + S C EF ++ +R  +K  +  L ++     +  P+ E  +    K+NCL+QA +  + ++ F L+ DT  I ++ +R+ R +  F     KK+A L  SV+ + K  + ++W  S  + +Q  K+   ++  +    +  F ++ +    EL  ++N H   G  I + +  +PK  L++  Q    S +K E+ +T               PDF +     G +    +F   +M   +L
Sbjct:  259 SLKAVTEIPAKFRNIFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLL-----MEVPLPWLNMKIVYMAPIKALCSQRFDDWKEKFGPVGLNCKELTGDTVMDDLFEIQHANIIITTPEKWDSVTRKWRDNSFIQLVRLFLIDEVHVIKDENRGPTLEVVVSR-MKTVQSLSRDLESASPVPVRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSSQTEFKFDLALNYKVYSVIRTYSDQKPTLVFCSTRKGVQQAASV-----LVKDAKFIISVEQK---LRLQKSAYSIRDSKLKDTLVYGVGYHHAGMELSDRKLVEGLFTSGDLPVLFTTSTLAMGMNMPAHLVVIKSTMHY--SGGVFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTREKYVQMLACNDTVESSLHRHLIEHLNAEIVLHTITDVNIALDWIRSTMLYIRALKNPSHYGFSSGLNKD-GIEAKLQELCLKNLKDLSSLDLIKMDEDVN-FKPTEAGRLMAWYYITFET---VKKFCAISGKETLLDLISMISSCNEFLDVQLRISEKRILNTLNKDPNRITIRFPMAERIKTREMKVNCLIQAQLGCIPIQDFALTQDTVKIFRNGSRIARWLSDFVAAQEKKFAVLLNSVILT-KCFKCKLWENSKHVSKQLDKIGISLSNTMVNAGLTSFKKIEEANARELELILNRHPPFGTQIKEAVAHLPKYELEVE-QIARYSDIKAEILVTIILRNFEQLQTKRTAPDFHYATLIIGDADNQVVFKHKIMDSVLL 1050

HSP 2 Score: 297.36 bits (760), Expect = 5.560e-81
Identity = 196/646 (30.34%), Postives = 330/646 (51.08%), Query Frame = 1

Query: 4060 KKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQ----DARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNK-SISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSR-------TRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIE--IQTFNITHNATRLA---AMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAI-VSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNL-KGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQ-----SLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAME 5922
            K+  +FN IQ++ F+ L  +D N  I APTGSGKTV  E+AI RL         + + VY+  +  L   R+ +W + FG +G    +LTG+T MD+   I  A+II++T E WD ++R+W+    IQ ++LF++D++H+I  ++ G TLEV+ SR       +R + S    P+R + +S ++ NA D+ EWL               HRP+ ++  +  F  + + T      A++  VY  I   S   P +VF  T K  ++ A +L    + D K      + + + +   +I +  L +TL  GVG+ H  + +++R L+  LF+S  + +L  + TL   +   A+LV++  T  Y+G   ++++YS  D++QM+GRA     D  A +VIM + + ++   + L     +ES L   L +H NAEIV  TI +   A+D++  T LY R  +NP++Y    G++   +   L EL    L DL +   I + +D++      G +  +YYI + T++ F  ++     +  L+ +I +  EF D+ LR  E  IL  + +     ++R P++E  R+     K N L+QA L  +PI+   L +D  +I     R+           RWL   +AA E
Sbjct:  275 KEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNMKIVYMAPIKALCSQRFDDWKEKFGPVGLNCKELTGDTVMDDLFEIQHANIIITTPEKWDSVTRKWRDNSFIQLVRLFLIDEVHVIKDENRGPTLEVVVSRMKTVQSLSRDLESASPVPVRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSSQTEFKFDLALNYKVYSVIRTYSDQKPTLVFCSTRKGVQQAASVL----VKDAKFIISVEQKLRLQKSAYSIRDSKLKDTLVYGVGYHHAGMELSDRKLVEGLFTSGDLPVLFTTSTLAMGMNMPAHLVVIKSTMHYSGG--VFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTREKYVQMLACNDTVESSLHRHLIEHLNAEIVLHTITDVNIALDWIRSTMLYIRALKNPSHYGFSSGLNKDGIEAKLQELCLKNLKDLSSLDLIKMDEDVNFKPTEAGRLMAWYYITFETVKKF-CAISGKETLLDLISMISSCNEFLDVQLRISEKRILNTLNKDPNRITIRFPMAE--RIKTREMKVNCLIQAQLGCIPIQDFALTQDTVKIFRNGSRIA----------RWLSDFVAAQE 901

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Mouse
Match: Polq (polymerase (DNA directed), theta [Source:MGI Symbol;Acc:MGI:2155399])

HSP 1 Score: 123.25 bits (308), Expect = 2.922e-27
Identity = 131/461 (28.42%), Postives = 216/461 (46.85%), Query Frame = 1

Query: 1579 ENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWD-IISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVAR---------TMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPM-EQEYLG----------INERKAVKRIELMND----LVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKC--LNRDTLGLFLRDKKASTLVLQQDL----DKVKNHD------LKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQL-PIESQLISKLADNLNAEIVMGTVRNIHESI 2847
            +N++  APT AGKT VA L +++ + +        RK   K ++I P  S+  E         +   LKV    G +  + +  +   I VCT E+ + +++R   E     L  +++ +   L    RG +LE ++ +         + +A  +S  +  ++IVG+SATLPN + +A +++ +    L+  D  +RPVP+ E   +G          + E + + +++   D    L YE + +    H VLIF  S+K     A  I  +   L+    GL    +    ++ Q+ L    D++K         LK+ +P+G A HHAGL + +R+ +E  F    I+VL +TSTL+ GVNLPA  VII+ T ++         L  L   QM GRAGR   DT G  I++   +E +  ++LL   L P+ S L          E+    +R I E I
Sbjct:  108 KNLVYSAPTSAGKTLVAELLILKRVLE-------TRK---KALFILPFVSVAKEKKCYLQSLFQEVGLKVDGYMGSTSPTGQ-FSSLDIAVCTIERANGLVNRLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYVTRKSASHQAESASTLSNAVQIVGMSATLPNLQLVASWLNAE----LYHTD--FRPVPLLESIKIGNSIYDSSMKLVREFQPLLQVKGDEDHIVSLCYETIQD---NHSVLIFCPSKKWCEKVADIIAREFYNLHHQPEGLVKSSEFPPVILDQKSLLEVMDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEGAFRQGFIRVLAATSTLSSGVNLPARRVIIR-TPIF-----SGQPLDILTYKQMVGRAGRKGVDTMGESILVCKNSEKSKGIALLQGSLEPVHSCL------QRQGEVTASMIRAILEII 536

HSP 2 Score: 98.2117 bits (243), Expect = 1.230e-19
Identity = 116/467 (24.84%), Postives = 210/467 (44.97%), Query Frame = 1

Query: 4123 ENVFIGAPTGSGKTVCAEIAIM-RLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYM-----------SSQLETPIRIIGLSYSLTNARDVGEWLDC--HHTATYNFNPSVRHRPLDIEIQTFNITHNAT-RLAAMSKPVYQT------ILKL-----SPNSPVIVFVPTMKQTEEIAFLLMG--YALSDK-KNFGRASE------------AIVSEYMRNIS--NEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPL-PLESHLDHQLHDHFNAEIVTKTIE--------NKQDAVDYLTWTFL 5364
            +N+   APT +GKT+ AE+ I+ R+   R+ A  +++     +A+ +       F  +G  V    G+T+   +  S   I V T E  + L  R  ++  +  + + +VD+LH++G  H G  LE++ ++  Y+           +S L   ++I+G+S +L N + V  WL+   +HT   +F P     PL   I+  N  ++++ +L    +P+ Q       I+ L       N  V++F P+ K  E++A ++    Y L  + +   ++SE             ++ +  R+ S  + +L  T+  GV F H  L+  ER+++   F    I++L  + TL   +   A  VI+  T +++G+      Y      QMVGRA    +D    S+++C+ ++K      L   L P+ S L  Q      A ++   +E          QD   Y   TFL
Sbjct:  108 KNLVYSAPTSAGKTLVAELLILKRVLETRKKA--LFILPFVSVAKEKKCYLQSLFQEVGLKVDGYMGSTSPTGQ-FSSLDIAVCTIERANGLVNRLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYVTRKSASHQAESASTLSNAVQIVGMSATLPNLQLVASWLNAELYHT---DFRPV----PLLESIKIGNSIYDSSMKLVREFQPLLQVKGDEDHIVSLCYETIQDNHSVLIFCPSKKWCEKVADIIAREFYNLHHQPEGLVKSSEFPPVILDQKSLLEVMDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEGAFRQGFIRVLAATSTLSSGVNLPARRVIIR-TPIFSGQPLDILTYK-----QMVGRAGRKGVDTMGESILVCKNSEKSKGIALLQGSLEPVHSCLQRQ--GEVTASMIRAILEIIVGGVASTSQDMQTYAACTFL 556

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. UniProt/SwissProt
Match: sp|O75643|U520_HUMAN (U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2)

HSP 1 Score: 2326.59 bits (6028), Expect = 0.000e+0
Identity = 1173/2156 (54.41%), Postives = 1570/2156 (72.82%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXX----XXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISN-YGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  +MG +  + KP   EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  L DKER+K    LLG    DT+Y+ LV+L  K+TDY   K   N +         ++  E D+++ +E+       + S+ D  G EA    TL+ +  A+G +                      +  + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR++++MI YCT L  +Q+  E+ +I  +M+ DP+ ++ L  L   + KED++  ER+R+ + R +++  D+E  D +          +LDL+++ FTQGSH M NK C+LPDGSFR+ + GY  V VPA KPKP  ++E L+ +  LP Y +A FE  KTLNRIQSK+Y+ ALE+DEN+LLCAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SF +RL +Y + VA L+GD  L +EEI+ TQIIVCTPEKWDII+RK  E+TYTQLV+L+I+DEIHLLHD+RGPVLEA+VAR +R ++ +    D+R++GLSATLPN ED+A F+ VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF DKHIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ++SKL D LNAEIV+G V+N  ++++WL Y YLYIRM ++P+LYG+  + L  DP LD    +L++TAA +L+K  ++ +DK++G F   E+GRIA++YY TN+T+    + LK ++ +IE+F+VFS  +EF+NITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQA+ISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   L  CK +++RMW   CPLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+H  PKL L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+     + RCVY+T +  LA+  Y +W + F   L K V+ LTG T+ D K + K +II+ST E WD+LSRRWK++K +QNI LF+VD++HLIG + NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+DV  WL C  T+T+NF+P+VR  PL++ IQ FNI+H  TRL +M+KPVY  I K SP  PVIVFVP+ KQT   A  ++    +D  ++ F   +E  +  Y+  +S+  L ETL  GVG++HE LS  ER L+ +LFSS +IQ++V S +LCW +   A+LVI+MDTQ YNGK   Y DY   D++QMVG AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH +HDHFNAEIVTKTIENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVE TL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +KVR L+E+I NA E+E++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+PHF     ++RC   GV++VFD+ME+EDE++ AL+   D ++ DVARF   YPNI+L+YEV    S+ +GG V V + L R+E+    V A  FP KREE WW+V+G+     LISIK L+     KV L+F AP  +G++ YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQP-RDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQT-DDTRYHVLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMS--------------------SKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETE-KEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQE--DVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEH-IKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAP-ATGAHNYTLYFMSDAYMGCDQEYKFSVDV 2126

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. UniProt/SwissProt
Match: sp|Q6P4T2|U520_MOUSE (U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Mus musculus OX=10090 GN=Snrnp200 PE=1 SV=1)

HSP 1 Score: 2325.44 bits (6025), Expect = 0.000e+0
Identity = 1171/2156 (54.31%), Postives = 1569/2156 (72.77%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXX----XXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISN-YGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  +MG +  + KP   EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  L DKER++    LLG    DT+Y+ LV+L  K+TDY   K   N +         ++  E D+++ +E+       + S+ D  G EA    TL+ +  A+G +                      +  + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR++++MI YCT L  +Q+  E+ +I  +M+ DP+ ++ L  L   + KED++  ER+R+ + R +++  D+E  D +          +LDL+++ FTQGSH M NK C+LPDGSFR+ + GY  V VPA KPKP  ++E L+ +  LP Y +A FE  KTLNRIQSK+Y+ ALE+DEN+LLCAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SF +RL +Y + VA L+GD  L +EEI+ TQIIVCTPEKWDII+RK  E+TYTQLV+L+++DEIHLLHD+RGPVLEA+VAR +R ++ +    D+R++GLSATLPN ED+A F+ VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF DKHIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ++SKL D LNAEIV+G V+N  ++++WL Y YLYIRM ++P+LYG+  + L  DP LD    +L++TAA +L+K  ++ +DK++G F   E+GRIA++YY TN+T+    + LK ++ +IE+F+VFS  +EF+NITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQA+ISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   L  CK +++RMW   CPLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+H  PKL L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+     + RCVY+T +  LA+  Y +W + F   L K V+ LTG T+ D K + K +II+ST E WD+LSRRWK++K +QNI LF+VD++HLIG + NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+DV  WL C  T+T+NF+P+VR  PL++ IQ FNI+H  TRL +M+KPVY  I K SP  PVIVFVP+ KQT   A  ++    +D  ++ F   +E  +  Y+  +S+  L ETL  GVG++HE LS  ER L+ +LFSS +IQ++V S +LCW +   A+LVI+MDTQ YNGK   Y DY   D++QMVG AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH +HDHFNAEIVTKTIENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVE TL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +KVR L+E+I NA E+E++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+PHF     ++RC   GV++VFD+ME+EDE++ AL+   D ++ DVARF   YPNI+L+YEV    S+ +GG V V + L R+E+    V A  FP KREE WW+V+G+     LISIK L+     KV L+F AP  +G + YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDMNKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQP-RDILCGAADEVLAVLKNEKLRDKERRREIDLLLGQT-DDTRYHVLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMS--------------------SKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEPEKERIVGKMEADPELSKFLYQLHETE-KEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQE--DVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEH-IKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAP-ATGGHNYTLYFMSDAYMGCDQEYKFSVDV 2126

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. UniProt/SwissProt
Match: sp|F1LNJ2|U520_RAT (U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Rattus norvegicus OX=10116 GN=Snrnp200 PE=1 SV=1)

HSP 1 Score: 2321.58 bits (6015), Expect = 0.000e+0
Identity = 1171/2159 (54.24%), Postives = 1570/2159 (72.72%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXX----XXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISN-YGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKS---HGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  +MG +  + KP   EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  L DKER++    LLG    DT+Y+ LV+L  K+TDY   K   N +         ++  E D+++ +E+       + S+ D  G EA    TL+ +  A+G +                      +  + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR++++MI YCT L  +Q+  E+ +I  +M+ DP+ ++ L  L   + KED++  ER+R+ + R +++  D+E  D +          +LDL+++ FTQGSH M NK C+LPDGSFR+ + GY  V VPA KPKP  ++E L+ +  LP Y +A FE  KTLNRIQSK+Y+ ALE+DEN+LLCAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SF +RL +Y + VA L+GD  L +EEI+ TQIIVCTPEKWDII+RK  E+TYTQLV+L+++DEIHLLHD+RGPVLEA+VAR +R ++ +    D+R++GLSATLPN ED+A F+ VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF DKHIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ++SKL D LNAEIV+G V+N  ++++WL Y YLYIRM ++P+LYG+  + L  DP LD    +L++TAA +L+K  ++ +DK++G F   E+GRIA++YY TN+T+    + LK ++ +IE+F+VFS  +EF+NITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQA+ISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   L  CK +++RMW   CPLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+H  PKL L +HLQPITRST+KVELTITPDF+W  K+   HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+     + RCVY+T +  LA+  Y +W + F   L K V+ LTG T+ D K + K +II+ST E WD+LSRRWK++K +QNI LF+VD++HLIG + NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+DV  WL C  T+T+NF+P+VR  PL++ IQ FNI+H  TRL +M+KPVY  I K SP  PVIVFVP+ KQT   A  ++    +D  ++ F   +E  +  Y+  +S+  L ETL  GVG++HE LS  ER L+ +LFSS +IQ++V S +LCW +   A+LVI+MDTQ YNGK   Y DY   D++QMVG AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH +HDHFNAEIVTKTIENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVE TL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +KVR L+E+I NA E+E++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+PHF     ++RC   GV++VFD+ME+EDE++ AL+   D ++ DVARF   YPNI+L+YEV    S+ +GG V V + L R+E+    V A  FP KREE WW+V+G+     LISIK L+     KV L+F AP  +G + YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQP-RDILCGAADEVLAVLKNEKLRDKERRREIDLLLGQT-DDTRYHVLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMS--------------------SKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETE-KEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQE--DVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKARLVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEH-IKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAP-ATGGHNYTLYFMSDAYMGCDQEYKFSVDV 2129

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. UniProt/SwissProt
Match: sp|Q9VUV9|U520_DROME (Putative U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Drosophila melanogaster OX=7227 GN=l(3)72Ab PE=2 SV=4)

HSP 1 Score: 2276.13 bits (5897), Expect = 0.000e+0
Identity = 1152/2165 (53.21%), Postives = 1556/2165 (71.87%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDY---------KAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSV--DMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLID-DPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKK--NFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVIL----TRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR +Q+EYK NSNLVL AD  LI+R  +DE TGEV   +  +D  +MG R  + KP+  EE++ KR KRD++    +  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  L D+ERKK    LLG  +TD ++  LV+L  K+TD+          AP     E  D+T  ++++ ++ +EE ++D+YGE++D ++ D G EA  + TL+    A    +                   N+     L+  DIDA+WLQR LSK + D    Q +  D+L++LK A +D++ EN+L+ ++G D FD ++ L+ N+ M+ YCT L  +QT  ER +I  +M+ +    +IL       R+ D   +E   + +AR +K       +     +   +    +L+L+ + FTQGSH M NK C+LPDGS+RK + GY  V VPA KP P +A+E L  +  LP YV+  FE  KTLNRIQS++YK AL+SDEN+LLCAPTGAGKTNVALLTMMREIGKHIN DGTI   DFKI+Y+APMKSLV EM  +F  RL  YNL V+ L+GD  L+RE+I  TQ+IVCTPEKWDII+RK  E+T+  LV+L+IIDEIHLLHDERGPVLEA+VART+R ++++   +  R+VGLSATLPN +D+A F+ V   +GLF FD+SYRPV +EQ+Y+G+ E+KA+KR ++MN++VYEK ME+AG++QVL+FVHSRKET  TA+A+++ CL +DTLG FL++  AS  VL+ + ++VKN +LK+LLPYGFA+HHAG+   DR  VE+LF D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG W ELSALDV+QM GRAGRPQYDTKG GI+ITN +EL +YLSLLN+QLPIESQ ISKL D LNAEIV+GTV+++ ++++WL YTYLYIRM +NP+LYGV +  I  DP L+ H  +L++TAA  LE++ +I +D+++G F   ++GRIA++YY T+ETM    + LK+++ +IE+F+VFS  +EFR+I+VREE+K+E++KL+E VP+PIKE  E+   K+N LLQAYISQLKLE F L SD  +I+QSAARLMRA+FE+ L++ WA L    L  CK +++RMW    PLRQFKK+P EI KKLEKK+ P+ RL D + HELGEL+   K+GKTI+K++HQ PKL L  H+QPITR T++VELTITPDF+W  K HG S+GFW+ +EDV SE ILH+E+FLLK+K+  D+H LKF+V +++PLPP Y++R VSD+WIG ET++ + F +++LPEKN P TELLDLQ LP  ALR  ++ES YS++   FN IQTQ F ++YNSDENVF+GAPTGSGK   AE AIMRLF+ + DARCVY+ +   LA L + +W   FG+L   V+KLTG T  D K I+K  ++++TA+ WDVLSRRWK++K +Q + LFIVD+L L+G +  G  LE++CSR RY+SSQ+E  IRI+ LS SLT+ARDV +WL C+  AT+NF+PSVR  PL++ IQ +N+THNATR+A MSKPVY  ILK S + PVIVFV + KQ    A  ++ YA SD +   F  A E  +  ++  ++++ L ETL+ GV ++HE LS ++  L+ +LF S ++Q+ V+S  LCW +   A+LVI+MDTQ YNGK+  Y+DY   D++QM+GRAN  + D DA+ V+MCQ++KKDF +KF++EPLP+ESHLDH++HDHFNAE+VTKTIENKQDAVDYLTWTFLY R+T+NPNYYNL+GV+HRHLSDHLSELVENTL DLE SKCI+++DD+D   +NLGMIA +YYI+YTTIE+FSLSL   +KVR LLE+I +A E+ED+ +RH E+ +L     R+   L  P     + +DP  K N+LLQA+LSR+ +   EL+ D  QIL K++RLIQACVDVLSSN WL PA+AAMELAQM+TQA W +DS LKQ+PHF+ P++++RC    ++TVFD+MELEDE +  L+   D ++ DVARF   YPNI+L YEV     +++G  V+V + L R+++    V A  FP KREE WW+V+G+P    L+SIK L+     KV L+F AP   G ++YTLY+MSDSYLGCDQEY+F+I V
Sbjct:    1 MADAAARQLQYEYKANSNLVLQADVRLIERPRRDEATGEVCSLVGKLDGTRMGDRYQRTKPEKTEERKVKRQKRDEAQYDFERMKGATLLSEGIDEMVGIVYRPKTQETRQTYEVLLSFIQEALGDQP-RDILCGAADEILAVLKNDRLKDRERKKDIDSLLGA-VTDERFALLVNLGKKITDFGSDAVNALTAAPN--NEEQIDETYGINVQFEESEEESDNDMYGEIRDDDAQDEGEEARIDHTLHAENLANEEAA------------------NNVKKERSLHPLDIDAYWLQRCLSKFYKDAMVSQSKAADVLKILKDAADDRDCENQLVLLLGYDCFDFIKQLKLNRQMVLYCTMLASAQTDSERQRIREKMRGNSALAKIL-------RQLDTGKSEDQEEGEARGSKRGKGDAEDGGAAAAGQVAGVRQLLELEEMAFTQGSHFMANKRCQLPDGSYRKQRKGYEEVHVPALKPVPFDANEELQPVDKLPKYVQPVFEGFKTLNRIQSRLYKAALDSDENMLLCAPTGAGKTNVALLTMMREIGKHINEDGTINAQDFKIIYVAPMKSLVQEMVGNFGRRLACYNLTVSELTGDHQLTREQIAATQVIVCTPEKWDIITRKGGERTFVSLVRLVIIDEIHLLHDERGPVLEALVARTIRNIETTQEEV--RLVGLSATLPNYQDVATFLRVKPDKGLFYFDNSYRPVSLEQQYIGVTEKKALKRFQVMNEIVYEKTMEHAGRNQVLVFVHSRKETGKTARAVRDMCLEQDTLGSFLKEGSASMEVLRTEAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILITNHSELQFYLSLLNQQLPIESQFISKLPDMLNAEIVLGTVQHLQDAVNWLGYTYLYIRMLRNPTLYGVSHDAIKADPLLEQHRADLLHTAACCLERSGLIKYDRKTGHFQVTDLGRIASHYYLTHETMLTYNQLLKQTLSEIELFRVFSLSSEFRHISVREEEKLELQKLMERVPIPIKESIEEHSAKVNVLLQAYISQLKLEGFALMSDMVFITQSAARLMRAIFEIVLTRGWAQLADKTLTLCKMIDRRMWQSMTPLRQFKKMPDEIAKKLEKKHFPWGRLYDLEPHELGELIRVPKLGKTIHKFVHQFPKLELSTHIQPITRGTLRVELTITPDFQWDEKVHGQSEGFWVLIEDVDSELILHHEFFLLKQKYSQDEHQLKFFVPVFEPLPPQYFLRIVSDRWIGAETQLPVSFRHLILPEKNMPPTELLDLQPLPISALRQPKFESFYSQRFPQFNPIQTQVFNAVYNSDENVFVGAPTGSGKMTIAEFAIMRLFTTQSDARCVYLVSEEALADLVFADWHSKFGSLDIKVVKLTGETGTDLKLIAKGQLVITTADKWDVLSRRWKQRKNVQLVNLFIVDELQLVGGE-EGPVLEIVCSRMRYISSQIEKQIRIVALSASLTDARDVAQWLGCNPNATFNFHPSVRPIPLELHIQGYNVTHNATRIATMSKPVYNAILKYSAHKPVIVFVSSRKQARLTAIDVLTYAASDLQPNRFFHAEEEDIKPFLERMTDKTLKETLAQGVAYLHEGLSASDHRLVEQLFDSGAVQVAVISRDLCWGMSISAHLVIIMDTQFYNGKNHSYEDYPITDVLQMIGRANRPNEDADAKCVLMCQSSKKDFFKKFINEPLPIESHLDHRMHDHFNAEVVTKTIENKQDAVDYLTWTFLYRRLTQNPNYYNLQGVTHRHLSDHLSELVENTLSDLEQSKCISVEDDMDTLPLNLGMIAAYYYINYTTIELFSLSLNSKTKVRGLLEIISSAAEYEDVVVRHHEEQVLRTLSQRLPNKLTGPNETAPKFNDPHIKTNLLLQAHLSRLQL-GPELQGDTEQILSKAIRLIQACVDVLSSNGWLSPAVAAMELAQMVTQAMWSKDSYLKQLPHFS-PEIVKRCTEKKIETVFDIMELEDEDRTRLLQLSDLQMADVARFCNRYPNIELNYEVVDKDRINSGSTVNVVVQLEREDEVTGPVIAPFFPQKREEGWWVVIGDPKTNSLLSIKRLTLQQKAKVKLDFVAP-SPGKHDYTLYYMSDSYLGCDQEYKFSIEV 2130

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. UniProt/SwissProt
Match: sp|Q9U2G0|U520_CAEEL (Putative U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Caenorhabditis elegans OX=6239 GN=snrp-200 PE=3 SV=1)

HSP 1 Score: 2080.45 bits (5389), Expect = 0.000e+0
Identity = 1070/2162 (49.49%), Postives = 1503/2162 (69.52%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLPIKDIDPKKM--GARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQKFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLI-DDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKK-MSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTIL----KLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDK--KNFGRASEA--IVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPIS-EDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKS-VSAGGQVSVQIHLARDEDN---ISSVYANNFPYKR-EESWWLVVGEPNQGHLISIK-LLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD +AR  Q+EY+ NSNLVL+ D  L DRR ++EPTGEVLPI D + +KM  G R +K K       QD++ KR + +     Q   +VL  D  +    Y P+T ETK  YE +L+ + + L +     +     DE+L+ LKN    DKE+KK  + LLG  LTD +   L++LS K++D+   +           +   E D D  E E        D E DDGG+  +              +      +  L   G+L + +  A    L+  DIDA W+QR+L+K+F DP   Q++  +++ +LK A +D++ EN+L+ ++G D+F+ ++ LR+N+LMI YCT L      +ER +IE +M++ P+ + ILA L+  D +  +V  E++++   +S K  A    E  +         MLDL ++TF+QGSHLM+NK CELPDGS+R+ K  Y  + VPA KP+P    E LV +++LP + + AF+  K+LNRIQS++  +AL S E++LLCAPTGAGKTNVALLTM++EIG H+  DG+++ D+FKIVYIAPMKSLV EM  SFS+RL  + + V  ++GD+ +S+E+   TQ+IVCTPEK+D+++RK  E+ Y Q+V+LLIIDEIHLLHD+RGPVLE+IV RT+R M+ +H   + R+VGLSATLPN +D+A F+ V K   L  FD+SYRPVP+EQ+Y+G+ E+KA+KR + MN++VY+K+ME+AGK QVL+FVHSRKET  TAKAI++ CL +DTL  F+R+  AST +L+ + ++ KN DLKDLLPYGFA+HHAG+   DR  VE+LF D+HIQVL ST+TLAWGVNLPAH VIIKGTQ+Y P+KG WTEL ALD+MQM GRAGRPQYD +G GI+ITN +EL YYLSL+N+QLP+ESQ++S+L D LNAE+V+GTV ++ E+ +WL YT+L++RM KNP+LYG+ +     DP L+    +LI+TA  +L+KA +I +DKRSG   + E+GRIA+++YCT E+M    K L ++  DI++F++FS  +EF+ ++VR+E+K+E++K+ E+ P+PIKE  ++   K N LLQAYISQLKLE F L +D  +++QSA RL RA+FE+ L + WA L   VL  CK V QR W    PL QFKK+P E+ + ++KKN  FDRL D   H+LG+L+   KMGK ++K+I Q PKL +   +QPITR+TM++ELTITPDF+W  K HGS++GFWIF+ED   E ILH+E+FLLK+KF +D+H++K  V ++DP+PPLYY+R VSD+WIG ET + I F +++LPEK  P TELLDLQ LP  A+ N+E+++++++     FN IQTQ F +++ S+ENV + AP GSGKT  AE+A++R F N  +A+ VY+T + D+A   Y +W +    A+G T++ LTG   MD K   +  +I+ST E WD +SRRWK++K++QN++LFI DDLH+IG+  NG   EV+CSRTRY+SSQLE+ +R++ LS SLTNARD+G WL C  +AT+NF PS R  PLD+EI++FN++HNA+R AAM +PVYQ I     KL P  P +VFVP  +QT  +A  L+  AL+D   K F R +E        + +I +E L E++SCGVGF+HE  +  + +++ +LF S +IQ+ VV   +C+ I   AYLV+VMDTQ YNGK  +Y+DY   D++ MVG AN   +D DA+ V+MCQT+K+ + +KFL +PLP+ESHLDH LHDHFNAEIVTKTIENKQDA+DYLTWT LY RMT+NPNYYNL+G +HRHLSD LSELVE TL DLENSKCIA+KD++D  ++NLGMIA++YYI Y TIE+FS+SLK  +K R L+E+I  ++EF ++P+RH EDVIL ++ +  RLP   ++++ +DP  K N+L+ A+LSRV +  AEL +D   I++++ RL+QACVDVLSSN WL PA+ AMEL+QM+TQA +  +  LKQ+PH +   LLER +A  V +VF+L+ELE++ +  ++     +L DVARF   YP+I++  E+    V++   + + + L RD D       V A  FP KR EE WWLV+G+     L++IK L+ +    V L+F APR  G +++ L+F+SDSYLG DQE+     V
Sbjct:    1 MADELARIQQYEYRQNSNLVLSVDYNLTDRRGREEPTGEVLPITDKEMRKMKMGDRAIKGKAPV----QDQKKKRKKKDDEKAQQFGRNVLV-DNNELMGAYKPRTQETKQTYEVILSFILDALGDVP-REVLCGAADEVLLTLKNDKFRDKEKKKEVEALLGP-LTDDRIAVLINLSKKISDFSIEE-----------ENKPEGDGDIYENEGVNVQFDSDEEEDDGGMVNEIKGDSEEESEEEEGVDT--DYTATLKGDGHLTEDEQKARG-ILHPRDIDAHWIQRSLAKYFKDPLIAQQKQTEVIGILKNAADDRDAENQLVLLLGFDQFEFIKCLRQNRLMILYCT-LLRQANEKERLQIEDDMRSRPELHPILALLQETD-EGSVVQVEKSKRDAEKSKK-AATAANEAISAGQWQAGRKMLDLNDLTFSQGSHLMSNKRCELPDGSYRRQKKSYEEIHVPALKPRPFAEGEKLVSVSELPKWAQPAFDGYKSLNRIQSRLCDSALRSKEHLLLCAPTGAGKTNVALLTMLQEIGNHLAEDGSVKLDEFKIVYIAPMKSLVQEMVGSFSKRLAPFGITVGEMTGDAQMSKEQFMATQVIVCTPEKYDVVTRKGGERAYNQMVRLLIIDEIHLLHDDRGPVLESIVVRTIRQMEQNHD--ECRLVGLSATLPNYQDVATFLRV-KPEHLHFFDNSYRPVPLEQQYIGVTEKKALKRFQAMNEVVYDKIMEHAGKSQVLVFVHSRKETAKTAKAIRDACLEKDTLSAFMREGSASTEILRTEAEQAKNLDLKDLLPYGFAIHHAGMNRVDRTLVEDLFADRHIQVLFSTATLAWGVNLPAHTVIIKGTQIYNPEKGRWTELGALDIMQMLGRAGRPQYDDRGEGILITNHSELQYYLSLMNQQLPVESQMVSRLTDMLNAEVVLGTVSSVSEATNWLGYTFLFVRMLKNPTLYGITHEQARADPLLEQRRADLIHTACVLLDKAGLIKYDKRSGIIQATELGRIASHFYCTYESMQTYNKLLVETCSDIDLFRIFSMSSEFKLLSVRDEEKLELQKMAEHAPIPIKENLDEASAKTNVLLQAYISQLKLEGFALQADMVFVAQSAGRLFRALFEIVLWRGWAGLAQKVLTLCKMVTQRQWGSLNPLHQFKKIPSEVVRSIDKKNYSFDRLYDLDQHQLGDLIKMPKMGKPLFKFIRQFPKLEMTTLIQPITRTTMRIELTITPDFKWDEKVHGSAEGFWIFIEDTDGEKILHHEFFLLKQKFCSDEHVVKMIVPMFDPMPPLYYVRIVSDRWIGAETVLPISFRHLILPEKYPPPTELLDLQPLPISAVTNKEFQTVFAESGFKVFNPIQTQVFRTVFESNENVIVCAPNGSGKTAIAELAVLRHFENTPEAKAVYITPMEDMATKVYADWKRRLEPAIGHTIVLLTGEQTMDLKLAQRGQLIISTPERWDNISRRWKQRKSVQNVKLFIADDLHMIGAS-NGAVFEVVCSRTRYISSQLESAVRVVALSSSLTNARDLGMWLGCSASATFNFMPSTRPVPLDLEIKSFNLSHNASRFAAMERPVYQAICRHAGKLEPK-PALVFVPVRRQTRPVAVALLTMALADGAPKRFLRLAEHDDTFQALLADIEDESLRESVSCGVGFLHEGTAPKDVHIVQQLFESNAIQVCVVPRGMCYQIEMSAYLVVVMDTQFYNGKYHVYEDYPIADMLHMVGLANRPILDSDAKCVVMCQTSKRAYYKKFLCDPLPVESHLDHCLHDHFNAEIVTKTIENKQDAIDYLTWTLLYRRMTQNPNYYNLQGTTHRHLSDALSELVELTLKDLENSKCIAVKDEMDTVSLNLGMIASYYYISYQTIELFSMSLKEKTKTRALIEIISASSEFGNVPMRHKEDVILRQLAE--RLPGQLKNQKFTDPHVKVNLLIHAHLSRVKL-TAELNKDTELIVLRACRLVQACVDVLSSNGWLSPAIHAMELSQMLTQAMYSNEPYLKQLPHCS-AALLERAKAKEVTSVFELLELENDDRSDILQMEGAELADVARFCNHYPSIEVATELENDVVTSNDNLMLAVSLERDNDIDGLAPPVVAPLFPQKRKEEGWWLVIGDSESNALLTIKRLVINEKSSVQLDFAAPR-PGHHKFKLFFISDSYLGADQEFDVAFKV 2128

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. TrEMBL
Match: A0A1S3IYW6 (U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Lingula unguis OX=7574 GN=LOC106168771 PE=4 SV=1)

HSP 1 Score: 2367.81 bits (6135), Expect = 0.000e+0
Identity = 1173/2154 (54.46%), Postives = 1593/2154 (73.96%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXX--XXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEK-LNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFG-ALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKK--NFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDA-RSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSK--SVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR +Q+EYK NSNLVL  DR+LIDRR++DE TGEV+  +  +   KMG + ++ KP  MEE++ KR KRD++ R +   K +S+L+  + +     Y PKT ET+  YE +L+I+ + L +    ++     DE+L  LKN  + DKERKK  + LLG  + + ++  LV+L  K++D+ + +    +++ +T  ++++ D+ +EE+E+D       +  + DD GVEA  + TL  S    G                        A +EK L+  DIDAFWLQR+L K++ DP   Q +  ++LE+LK + +D+E EN+L+ ++G ++FD +++LR+++ MI +CT L  +Q+ EER KIE +M +D   ++IL  L+  D KED+V  ER R+   R  ++ AD+E  D++   + G+V +LDL+++ F  GSHLM NK C+LPDGSFRK + GY  V VPA KPKP E +E  V I  LP Y + AFE  K+LNRIQS++   ALESDEN+L+CAPTGAGKTNVALLT++REIGKHIN DGTI  D+FKI+Y+APM+SLV EM  SF++RL SY ++V+ LSGD  LSRE+I  TQ+IVCTPEKWDII+RK  ++ YTQLV+L+IIDEIHLLHDERGPVLE +V+RT+R ++++    D+R+VGLSATLPN ED+A F+ VD  +GLF FD+S+RPVP+EQ+Y+G+ E+KA+KR ++MND+VYEKVME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTL  FL++  AST +L+++ ++VKN +LKDLLPYGFA+HHAG+   DR  VE+LF D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG W EL ALDVMQM GRAGRPQYDTKG GI+ITN +EL YYLSL+N+QLPIESQ I+KLADNLNAE+V+GTV+ + +++ WL YTYLYIRM + P+LYG+  + L DDP L+   ++L++TAA +++K  ++ +DK+SG F   E+GRIA+YYYCTN++M    + LK ++ +IE+F+VFS  +EFRNITVREE+K+E+ KLLE VP+PIKE  E+P  K+N LLQAYISQLKLE F L +D  YI+QSA RLMRA+FE+ L + WA L    L  CK +++RMW    PLRQFKK+P E+ KK+EKKN P++R  D  H+E+GEL+   K+GKTI+KY+HQ PKL L +H+QPITRST+KVELTITPDF+W  K HG S+ FWI VEDV SE ILH+EYFLLK K+  D+HI+KF+V +++PLPP Y+IR VSD+WIG ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +E +Y +K  FFNAIQTQ F ++YN D+NVFIGAPTGSGKT+ AE AI+R+ +   + RCVYVT  + LA   Y +W   F   LGK V++LTG T  D K ++K +IIVST E WDVLSRRWK++K +QN+ LFIVD+LHLIG + +G  LEV+CSR RY+SSQ+E  IRI+ LS SL+NA+D+ +WL C  T T+NF+P+VR  PL++ IQ FNI+HNA+RL AM+KP YQ I + SP  P +VFVP+ KQT   A  ++ +A +D++   F    E  +  ++  ++++ L ET+S GV ++HE L+  ER ++ +LF+S +IQ++VVS +LCW++   ++LV+VMD+Q Y+GK   Y+DY   D++QMVGRAN  + DDA ++VI+CQ++KKDF +KFL+EPLP+ESHLDH LHDHFNAEIVTKTIENKQDAVDYLTWTFLY RM +NPNYYNL+GVSHRHLSDHLSELVENTL DLE SKCI+I+D++DVS +NLGMIA +YYI+YTTIE+FS+SL   +K++ L+E+I NA E++ +P+RH E  IL ++   L   I+ + + +DP  K N+LLQA+LSR+ +  AEL+ D   IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+PHF   ++++RC+   + TVFD+ME+ED+++  L++  + ++ DVARF   YPNI++TYEV +  +V +G  V+V + L R+++    V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP   G + Y LY+MSDSY+GCDQEY+F+I+V
Sbjct:    1 MADAAARQLQYEYKANSNLVLQVDRSLIDRRARDEATGEVMSLVGKLVGTKMGDKSMRTKPPQMEERKAKRRKRDEAQRDMLKMKGQSLLSEGIDEMVGILYRPKTPETRQTYEVLLSIMQSALGDQP-RDVLCGAADEVLAVLKNDRMKDKERKKEVEALLGE-MQEERFALLVNLGKKISDWGSEEKMQTDDSMETFGVNVQFDESEEEDEEDAFGEARGESEDEDDEGVEAHVDATLVSSLSVEGG-----------------------AKAEKELHPRDIDAFWLQRSLRKYYDDPMVAQAKAGEVLEILKSSSDDREAENQLVVLLGFNQFDFIKVLRQHRQMILFCTMLAQAQSQEERAKIEEKMSSDANLSKILHTLQETD-KEDLVREERERRQAKRQTRVDADLEAMDTDERQDVGNVQLLDLEDLVFGMGSHLMANKRCQLPDGSFRKQRKGYEEVHVPALKPKPYENNETRVPIDRLPKYAQPAFEGFKSLNRIQSRLSNAALESDENLLVCAPTGAGKTNVALLTILREIGKHINPDGTINTDEFKIIYVAPMRSLVQEMTGSFTKRLSSYGIQVSELSGDHQLSREQIMATQVIVCTPEKWDIITRKGGDRIYTQLVRLMIIDEIHLLHDERGPVLECLVSRTIRNIETTQE--DVRLVGLSATLPNYEDVATFLRVDPEKGLFYFDNSFRPVPLEQQYVGVTEKKAIKRFQVMNDIVYEKVMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLSAFLKEGSASTEILRREAEQVKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELGALDVMQMMGRAGRPQYDTKGEGILITNHSELQYYLSLMNQQLPIESQFIAKLADNLNAEVVLGTVQTVKDAVQWLGYTYLYIRMLRAPTLYGIAHDDLKDDPWLEQRRKDLVHTAAMMIDKNNLMKYDKKSGHFQVTELGRIASYYYCTNDSMSTYNQLLKPTLSEIELFRVFSLSSEFRNITVREEEKLELAKLLERVPIPIKESIEEPSAKVNVLLQAYISQLKLEGFALVADMVYITQSAGRLMRALFEIVLHRGWAQLADKALALCKMIDKRMWQSMSPLRQFKKIPEEVIKKIEKKNFPWERFYDLGHNEIGELIRMPKLGKTIHKYVHQFPKLELAVHIQPITRSTLKVELTITPDFQWEEKVHGHSEAFWILVEDVDSEVILHHEYFLLKNKYAQDEHIVKFFVPVFEPLPPQYFIRVVSDRWIGAETQLPVSFRHLILPEKVPPPTELLDLQPLPVSALRNPHFEQLYQEKFQFFNAIQTQVFNTVYNGDDNVFIGAPTGSGKTISAEFAILRMLTQSPEGRCVYVTPKDALADQIYADWHNKFALQLGKKVVQLTGETATDLKLLAKGNIIVSTPEKWDVLSRRWKQRKNVQNVNLFIVDELHLIGGE-DGPVLEVVCSRMRYISSQIERNIRIVALSSSLSNAKDIAQWLGCSTTGTFNFHPNVRPVPLELHIQGFNISHNASRLMAMAKPAYQAINRHSPKKPALVFVPSRKQTRLTAIDILTFAAADRQPSRFLHVKEEDLEPFLEKLTDKTLKETISNGVAYLHEGLTEVERRVVEQLFTSGAIQVVVVSRSLCWALQVVSHLVVVMDSQFYDGKIHAYEDYPVTDVLQMVGRANRPNEDDAGKAVILCQSSKKDFFKKFLYEPLPVESHLDHFLHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMAQNPNYYNLQGVSHRHLSDHLSELVENTLHDLEQSKCISIEDEMDVSPLNLGMIAAYYYINYTTIELFSMSLNNKTKIKGLIEIISNAAEYDSIPIRHREANILKQLGSRLPNKIN-NPKYTDPHVKTNLLLQAHLSRMQL-PAELQSDTEDILTKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWGKDSYLKQLPHFT-AEIIKRCQEKNIDTVFDVMEMEDDERNTLLSLSETEMADVARFCNRYPNIEMTYEVEEKDNVKSGSPVNVAVTLEREDEIAGPVVAPFFPQKREEGWWVVIGDPKSNSLISIKRLTLQQKAKVKLDFVAP-SPGKHSYVLYYMSDSYMGCDQEYKFSIDV 2121

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. TrEMBL
Match: A0A087TVN5 (U5 small nuclear ribonucleoprotein helicase (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_25475 PE=4 SV=1)

HSP 1 Score: 2343.15 bits (6071), Expect = 0.000e+0
Identity = 1179/2158 (54.63%), Postives = 1570/2158 (72.75%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNL-SDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXXXSES---DDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEK-LNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMED--SNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFG-ALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKK--NFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPIS-EDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVS--KSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++QFEYK NSNLVL AD  LI+RR +DE TGEV+  +  ++  +MG R  + KP   EEK+ KR+KRD+S       K +++L+  +       Y PKTAETK  YE +L+ +   L +    +I     DE+L  LKN  +  DK+R++  + LLG  L   +Y  LV+L  K+TDY           +      + +  ++ +EE++        E    ++ G EA  ++TL+ +   +                     Q  +  S K L+  DIDA+WLQR LSK + DP   Q R  ++LE+LK A +D+++EN+L+ ++G ++F+ +++LR+++  I YCT L   Q+  E+ K++ +M++DP+  +IL  L N + KEDI+  ER R+ Q R A++ AD+E  D     +       +LDL+++TF QGSH M NK C+LPDGSFRK + GY  + VPA KPKP E+ E+L+ I  LP YV+ AFE  K+LNRIQS++ KTALE+DEN+LLCAPTGAGKTNVALL MMREIGKHIN+DGTI  D+FKI+YIAPM+SLV EM  +FS+RLKSYN++V+ L+GD  L+RE+IN TQ+IVCTPEKWDI++RK  E+TYTQLV+L+I DEIHLLHDERGPVLEA+VART+R ++ +   +  R+VGLSATLPN ED+A F+ V +  GLF FD+S+RPVP+EQ+Y+GI E+K +KR  LM +++YEKVME+AGK+QVLIFVHSRKET  TA+ I++ CL +DTLG FLR   AST VL+ + D VKNH+LK+LLPYGFA+HHAG++  DR  VE+LF D+HIQVLVST+TLAWGVNLPAH VIIKGTQ+Y P+KG W EL ALDV+QM GRAGRPQYDTKG GI+ITN +EL YYLSL N+QLPIESQLISKL D LNAEIV+G ++++ E++ WL YTYLYIRM ++P+LYGV+ V  +DP L+ H  +LIYTAA++L+K+ ++ FDK++G F   E+GRIA++YYCT ETM    + LK+++ +IE+F+VFS   EF+ + +REE+K+E++KL+E VP+PIKE  E+   K+N LLQAYISQLKLE   L +D  YI+QSA RLMRA+FE+ L + WA LT   L  CK +++RMW    PLRQFKK+P E+ KK+EKKN P++RL D   +E+GEL+   K+GKT++KY+HQ PKL+L  H+QP+TR+T++VELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK KF  D+HI+KF+V +++PLPP Y+IR VSD+WIG ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  +FN IQTQ F S+YNSD+NVF+GAPTGSGKT+CAE AI+RL S   D RCVYVT    LA++ Y +W   F   + K V+ LTG T+ D K ++K +II+ST E WDVLSRRWK+++ +QNI LFIVD+L LIG + +G  LEVICSR RY+SSQ E PIRI+ LS SL NA+DV +WL     +T+NF P+VR   L++ IQ FNITHNA+RL AMSKPVYQ I +LSP  PVIVFVP+ KQ+   A  ++ Y  S+ +   F   +++ +  ++  I ++ L ET+S GV ++HE L+ ++  ++ +LF S +IQ++VVS  LCW +   A+LV++MDTQ YNGK   Y+DYS  D++QMVGRAN    D D + V++CQ++KKDF  KFL+EPLP+ESHLDH LHDHFNAEIVTKTI+NKQDAVDYLTWTFLY RMT+NPNYYNL+GV+HRHLSDHLSELVENTL DLE S+CI+I+D++DVS +NLGMIA +YYI+YTTIE+FS+SL   +KVR LLE+I +A E+E +P+RH ED +L ++    RLP    + + SDP  K N+LLQA+LSR+ + +AEL+ D   IL K+VRLIQACVDVLSSN WL PALAAMELAQM+TQ  W++DS LKQ+PHF  P++++RC   GV+TVFD+MELEDE +  L+   D ++ DVARF   YPNI+L+YEV   +S+ +G  V+V + L R+++    V A  FP +REE WW+V+G+P    LISIK L+     KV L+F AP  +G + YTLYFMSDSY+GCDQEY+F I V
Sbjct:    1 MADAAARSLQFEYKANSNLVLQADTRLIERRPRDEATGEVVSLVGKLEGSRMGDRYQRTKPAKAEEKKAKRMKRDESRYDFSKLKGQTLLSEGIEDMVGILYRPKTAETKQTYEVLLSFIQEALGDQP-RDILCGAADEVLAVLKNEKIRDDKDRRRETEALLGQ-LAQERYAVLVNLCKKITDYGVDDKVQTTEENIDETYGVNVQFEESDEEEEDMCGEVREEDSNDENEGDEAIVDSTLHATNLDSS--------------------QDTMGKSGKSLHPRDIDAYWLQRKLSKFYDDPVVAQTRAGEVLEILKTAVDDRDVENQLVLLLGYNQFEFIKILRQHRQTILYCTLLASLQSGAEKTKLKEKMQSDPELEKILRQLENTE-KEDIIQEERERRAQVRQARVDADLEAMDIDGESVPQLQQCRVLDLEDLTFAQGSHFMANKRCQLPDGSFRKQRRGYEEIHVPALKPKPFESSESLMPIEKLPKYVQHAFEGYKSLNRIQSRLCKTALETDENLLLCAPTGAGKTNVALLCMMREIGKHINSDGTINADEFKIIYIAPMRSLVQEMVGNFSKRLKSYNIQVSELTGDHQLTREQINATQVIVCTPEKWDIVTRKGGERTYTQLVRLMIFDEIHLLHDERGPVLEALVARTIRNIEMTQEEV--RLVGLSATLPNYEDVASFLRVTQATGLFYFDNSFRPVPLEQQYIGITEKKPIKRFMLMKEILYEKVMEHAGKNQVLIFVHSRKETGKTAREIRDMCLEKDTLGQFLRGGSASTAVLETEADHVKNHELKNLLPYGFAIHHAGMSRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQIYSPEKGRWVELGALDVLQMLGRAGRPQYDTKGEGILITNHSELQYYLSLFNQQLPIESQLISKLPDMLNAEIVLGNIQSMKEAVTWLGYTYLYIRMLRSPALYGVQ-VNSEDPLLEKHRADLIYTAATLLDKSNLLKFDKKAGIFQVTEVGRIASHYYCTYETMTTYTQLLKQTLSEIELFRVFSLSGEFKYLNIREEEKLELQKLMERVPIPIKESIEESSAKVNVLLQAYISQLKLEGLALMADMVYITQSADRLMRAIFEIVLHRGWAQLTDKALSLCKMIKRRMWQSMTPLRQFKKIPDEVVKKIEKKNFPWERLYDLGPNEIGELLRMPKLGKTVHKYVHQFPKLDLSAHIQPVTRATLRVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKSKFCQDEHIVKFFVPVFEPLPPQYFIRIVSDQWIGSETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNPFFESLYKDKFPYFNPIQTQVFNSVYNSDDNVFVGAPTGSGKTICAEFAILRLLSQNPDGRCVYVTPKESLAEIIYADWTAKFSTVMNKKVVLLTGETSTDLKLLAKGNIIISTPEKWDVLSRRWKQRRNVQNINLFIVDELQLIGGE-DGPILEVICSRMRYISSQTEKPIRIVALSSSLANAKDVAQWLGASPNSTFNFPPNVRPVQLELHIQGFNITHNASRLLAMSKPVYQAITRLSPRKPVIVFVPSRKQSRLTAIDILTYCASEAQPARFLHCTDSDIQPFVDKIVDKTLKETISNGVAYLHEGLNSSDSKIIGQLFESGAIQVVVVSRNLCWGLSLAAHLVVIMDTQYYNGKIHTYEDYSITDVLQMVGRANRPKYDEDGKCVLLCQSSKKDFFTKFLYEPLPVESHLDHCLHDHFNAEIVTKTIDNKQDAVDYLTWTFLYRRMTQNPNYYNLQGVTHRHLSDHLSELVENTLNDLEQSRCISIEDEMDVSPLNLGMIAAYYYINYTTIELFSMSLNSKTKVRGLLEIISSAAEYEGVPIRHREDNLLKQLAN--RLPHKLANPKFSDPHVKTNLLLQAHLSRMQL-SAELQSDTEDILSKAVRLIQACVDVLSSNGWLSPALAAMELAQMVTQGMWNKDSYLKQLPHFT-PEIVKRCTEMGVETVFDVMELEDEDRNKLLQLNDAQMADVARFCNRYPNIELSYEVQDKESIMSGQTVNVSVQLEREDEVTGPVIAPLFPQRREEGWWVVIGDPKTNSLISIKRLTLQQKAKVKLDFVAP-NAGEHTYTLYFMSDSYMGCDQEYRFNIRV 2126

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. TrEMBL
Match: A0A3S3P5W2 (Antiviral helicase Slh1-like protein OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_04062 PE=4 SV=1)

HSP 1 Score: 2335.84 bits (6052), Expect = 0.000e+0
Identity = 1180/2162 (54.58%), Postives = 1588/2162 (73.45%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLPIKD-IDPKKMGARVLKRKP-DCMEEKQDKRIKRDQSNRTLDYQ----KTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDY---KAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDD-GGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHIN-TDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFS-NRQDARCVYVTALNDLAQLRYTEWMKTFGA-LGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKK--NFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVS--KSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL AD  LI++R +DE TGEV+ +   ++  +MG R  + KP   ++  + K+  +  ++ T  Y+    K +S+L+  +       Y PKT ET+ +YE +L+ +   L +    ++     DE+L  LKN  L +KER+K   ELLGN+LT+ +Y+ LV+L  K+TDY   + P+  T E+ D+T  ++++ ++  EE ++ +     D + DD  G EA   +TL+ S     T   + G+ T  P  G             L+  +IDA+WLQR LSK + DP   Q +  ++L +LK A +D+++EN+L+ ++G + FD +++L +N+ MI YCT L  +Q+  E+NKI  +M +D + +RIL  L N D K   VT ER RK++++ ++ +A+    D   ++      +LDL ++ F QGSH M NK C+LPDGSFRK + GY  + VPA KPKP + +ENLV I  LP Y + AFE  KTLNRIQS +YK+ALE DEN+L+CAPTGAGKTNVALL+MMREIGKHIN  DG+I  DDFKI+YIAPM+SLV EM N+FS+RL SYN+KVA L+GD  LSRE+INETQ+IVCTPEKWDII+RK  ++TYTQ+V+L+I DEIHLLHD+RGPVLE +VAR +R+++++    D+R++GLSATLPN ED+A F+ V K  GLF FD+S+RPVP+EQ+++GI E+KA+KR +LMN+++YEKV+E AGK+QVLIFVHSRKET  TA+ +++ CL +DTLGLFLR+  AST VL+ + ++VKN +LKDLLPYGFA+HHAG+   DR  VE+LFTD+HIQVLVST+TLAWGVNLPAH VIIKGTQVY PDKG WTEL ALDV+QM GRAGRPQYDTKG GI+IT  +EL YYLSLLN+QLPIESQ+++KL D LNAE+++G V+N+ E+I+WL YTYLYIRM +NP+LYG+  +   +DP L+ H  NLI+TAAS+L+K+ ++ F+++SG F   E+GRIA++YYCT++TM    + LK ++ +IE+F+VFS   EFRNIT+REE+K+E++KL+E VP+P+KE  ++P  K+N LLQAYISQLKLE   L +D  YI+QSAARLMRA+ E+ L + WA L    L  CK +++RMW    PLRQFKK+P E+ KK+EKKN P++RL D   +E+GEL+   K+GKT++KY+HQ PKL L  H+QPITRST+KVELTI PDF+W  K H +S+ FWI VEDV  E ILH+EYFLLK K+  D+HI+KF+V I+DPLPP Y+IR VSD+WIG ET + + F +++LPEK  P TELLDLQ LP  ALRN  YE++Y  K  +FN IQTQ F +LYN+D+NVF+GAPTGSGKTVCAE AI RLF+ + Q+ +CVYVT    LA++ + +W   FG+ LGK V+ LTG T  D K ++K +IIV+T E WD+LSRRWK++K +QNI LFIVD+L LIG    G  LEV+CSR RY+SSQ+E PIRI+ LS SL NA+DV +WL C+   T+NF+P+VR  PL++ I+ FN THN++RL AMSKPVYQ IL  SP  PVI+FVPT KQT+  A  ++ Y  +D +   F   +E  +  +++ +S+  L +T+S GV +IHE LS  +R L+ +LF+S +IQ++V+S TLC+SI    +LVI+MDTQ YNGK   Y+DY   D+IQMVGRAN   +D D + V+ CQ++KKDF +KFL++PLP+ESHLDH LHDHFNAEIVTKTIENKQDAVDYLTWTFLY RMT+NPNYYNL+GV+HRHLSDHLSELVENTL DLE SKCI+I++D+DVS +NLGMIA +YYI+Y+TIE+FS+SL   +K+R L+E+I +A E+E +P+RH ED IL +I + +   I +  + SDP  K N+L+QA+LSR+ +   EL+ D  +IL KS+RLIQACVDVLSSN WL PALAAMELAQM+TQ+ W++DS LKQ+PHF   ++++RC   GV+T+FD+MEL+DE +  L+   D K+ DVA+F   YPNI+LTYEV     + +G  V+V + L R+++ +  V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP   G + YTLYFMSD+Y+GCDQEY+F I+V
Sbjct:    1 MADAAARSLQYEYKANSNLVLQADTRLIEKRPRDEATGEVISLAGKLEGSRMGDRYQRTKPSSALKSDEKKKKSKKAASETSKYELSKLKAQSLLSEGIESMVGILYRPKTPETRQIYEVLLSFIQESLGDQP-RDVLCGAADEVLAVLKNDKLKEKERRKDCSELLGNSLTEERYSVLVNLCKKITDYGVEEKPQHITEESIDETYGVNVQFEESDEENDELMGEIRDDQDEDDFEGEEAPFESTLHASNL--DTNMPLTGSQTGAPSKG-----------AALHPREIDAYWLQRKLSKTYDDPVVAQSKAAEVLNILKTATDDRDVENQLIYLLGCNIFDFIKVLLQNRQMILYCTLLASAQSVAEKNKIREKMLSDSELSRILRMLENTDEKA--VTEERERKSRSKESRTKAEDADFDEESVAQLSRCKILDLDDLAFAQGSHFMANKRCQLPDGSFRKQRKGYEEIHVPALKPKPFDPNENLVSIEKLPRYAQPAFEGFKTLNRIQSHIYKSALEKDENLLICAPTGAGKTNVALLSMMREIGKHINPNDGSINVDDFKIIYIAPMRSLVQEMVNNFSKRLSSYNIKVAELTGDHQLSREQINETQVIVCTPEKWDIITRKGGDRTYTQVVRLVIFDEIHLLHDDRGPVLETLVARMVRSIETTQE--DIRLIGLSATLPNYEDVAAFLRV-KKSGLFHFDNSFRPVPLEQQFIGITEKKALKRYQLMNEILYEKVIEQAGKNQVLIFVHSRKETGKTARTVRDMCLEKDTLGLFLREGSASTEVLRTEAEQVKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFTDRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYNPDKGRWTELGALDVLQMLGRAGRPQYDTKGEGILITQHSELQYYLSLLNQQLPIESQMVAKLPDLLNAEVILGNVQNVKEAINWLGYTYLYIRMLQNPALYGISHDAAKEDPLLEKHRANLIFTAASLLDKSNLVKFERKSGTFQVTELGRIASHYYCTHQTMATYNQLLKPTLSEIELFRVFSLSGEFRNITIREEEKLELQKLMERVPIPVKESIDEPSAKVNVLLQAYISQLKLEGLALMADMVYITQSAARLMRAIHEIVLHRGWAQLADKALSLCKMIDKRMWQSMSPLRQFKKIPEEVVKKIEKKNFPWERLYDLGPNEIGELLRMPKLGKTVHKYVHQFPKLELSAHIQPITRSTLKVELTIIPDFQWDEKVHRTSEAFWILVEDVDQEVILHHEYFLLKAKYAQDEHIVKFFVPIFDPLPPQYFIRIVSDRWIGSETILPVSFRHLILPEKYPPPTELLDLQPLPVSALRNPAYEALYKDKFPYFNPIQTQVFNALYNTDDNVFVGAPTGSGKTVCAEFAIFRLFTQSAQEPKCVYVTPKEQLAEIIFNDWSHKFGSQLGKKVVLLTGETATDLKLLAKGNIIVATPEKWDILSRRWKQRKNVQNINLFIVDELQLIGGDE-GPVLEVVCSRMRYISSQIERPIRIVTLSSSLANAKDVAQWLGCNSAMTFNFHPNVRPVPLELHIRGFNQTHNSSRLLAMSKPVYQAILHHSPKKPVIIFVPTRKQTKITAVDIITYTAADSQVNRFLHCTENDIEPFIQRLSDSTLKQTISNGVAYIHEGLSAQDRRLVEQLFNSGAIQVVVISRTLCFSISVCGHLVIIMDTQYYNGKIHAYEDYPITDVIQMVGRANRPLLDEDGKCVLFCQSSKKDFFKKFLYDPLPVESHLDHCLHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGVTHRHLSDHLSELVENTLNDLEQSKCISIEEDVDVSPLNLGMIAAYYYINYSTIELFSMSLNSKTKIRGLIEIISSAAEYEQIPIRHHEDTILKQILEKVPNKI-QSPKFSDPHVKTNLLIQAHLSRMSL-PPELQSDTEEILSKSIRLIQACVDVLSSNGWLSPALAAMELAQMVTQSVWNKDSYLKQLPHFTS-EIIKRCSERGVETIFDIMELDDEDRNNLLQLDDAKMADVAKFCNRYPNIELTYEVQDKHKIESGSSVNVIVQLEREDEVVGPVIAPFFPQKREEGWWVVIGDPKTSSLISIKRLTLQQKAKVKLDFTAP-APGDHTYTLYFMSDAYMGCDQEYKFNIHV 2138

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. TrEMBL
Match: A0A3S1AA11 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_005773 PE=4 SV=1)

HSP 1 Score: 2332.75 bits (6044), Expect = 0.000e+0
Identity = 1162/2160 (53.80%), Postives = 1568/2160 (72.59%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTD-PNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKK---------NFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPIS-EDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL+ DRTLIDRR +DE TGEV+  +  +   +MG + LK KP  MEE++ KR KRD++   +   K  ++L+  + +     Y PKT ET+  YE +LN +   L +    ++     DE+LI LKN    D+E+KK  + LLGN L + ++  LV+L  K+TD+   +             H     D +E         +  + D G V  +     ++ +   G  +    T         L ++        L+  +IDAFW+QR +SK + D PN  Q + KD+LE+LK A +D+E E KL+ ++ V  F+ ++ LR+++ MI YCT L  +QT  E+ KI+ +M  D + + IL  L+  D ++DIV+ ER R+ QAR  ++ ADIE  D       G V  L L+++ F+QGSHLM NK C+LPDGS+RK + GY  V VPA KPKP + DE LV I  LP Y + AFE+ K+LNRIQS++   A+E+D+N+LLCAPTGAGKTNVALLT+MREIGKH+N DGTI  DDFKI+YIAPMKSL  EM  +FS+RL SYNL+V  L+GD  L+RE+I  TQ+IVCTPEKWDII+RK  EKTYTQ V+LLI DEIHLLHD+RGPVLE++VART+R ++S+    D+R+VGLSATLPN ED+A F+ VD   GLF FD+S+RPVP++Q+++GI E+KA+KR +LMND+VYEKV+E+AGK+QVL+FVHSRKET  TA+ I++ CL +DTLGLF+++  AST+VL+Q+ ++VK+ +LKDLLPYGFA+HHAG+   DR  VE+LF D+HIQVL+STSTLAWGVNLPAH VIIKGTQ+Y P+KG W ELSALDV+QM GRAGRPQYDTKG GIMITN +EL YYLSL+N+QLPIESQ ISK+ADNLNAE+V+GTV NI E++DWL YTYLYIRM +NP+LYGV  + L +DP L    ++L++TAA IL+K  ++ +D+++G     E+GRI+++YY T+E+M    + LK ++ +IE+F+VFS  +EF+ +TVREE+K+E+ KLLE VP+PIKE  E+P  K+N LLQAYISQLKLE F L  D  +I+QSA RLMRA+FE+ L   WA L    L  CK V++RMW    PLRQF+K+P ++ KK+EKKN PF+RL D  H+E+GEL+   KMGK I+K+I Q P+L L +H+QPITRST+KVELTITPDF+W  K HG S+ FWI VEDV SE +LH+EYFLLK KF  D+H++KF+V +++PLPP Y+IR VSD+WIG ET++ + F +++LPE+  P TELLDLQ LP  ALRN ++E++YSKK + FN IQTQ F S+YNSD+NVF+GAPTGSGK++C E A++R+FS   + RCVYV  L+ LAQ  Y +W   F G LGK V+ LTG T  D K ++K +I++ST + WDVLSRRWK++K +QN+ LFIVD+LHLI S   G  LEVICSR RY+SSQLE  IRI+ LS SL+NA+D+ +WL C  +A +NF+P+VR  PL++ IQ FN++HNA+R+ AM+KP YQ ++K S   PV+VFVP+ KQT+  A  ++  A ++ +          F   +E  +  ++  IS+  L ETL+ GVG++HE L+  ER L+ +LFSS ++Q+LVV+ +L W I   A+LVIVMDTQ Y+GK   Y+DY   D++QM+G+AN   +D + ++VIMCQ++KK+F +KFL+EPLP+ESHLDH LHDHFNAEIVTKTIENKQDAVDYLTWTF+Y RMT+NPNYYNL+GV+HRHLSDHLSE+VENT+ DLE SKCI I+DD DV  +NLGMIA +YYI+YTTIE+FS+SL   +K++ L+E++ NA E+E+LP+RHGE  IL ++    RLP    + + +DP  K N+LLQA+LSR+P+ +AEL+ D   IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+PHF    +++RC+   ++++FD+ME+ED+ +  L+   + ++ DVARF   YPNI+LTYEV   +S+ +G  ++V + L R+++ I  V A  FP KREE WW+V+G+P    L+SIK L+     KV L+F AP   G Y Y ++FMSD+Y+GCDQEY+F+++V
Sbjct:    1 MADATARSLQYEYKANSNLVLSVDRTLIDRRGRDEATGEVMSLVGKLAGSRMGDKALKSKPPLMEERKIKRRKRDEAQHDMVKMKGATLLSEGIDEMVGILYRPKTTETRQTYEVLLNFIQAALGDQP-RDVLCGAADEVLIVLKNDRKKDREKKKEVESLLGN-LAEERFALLVNLGKKITDWSQEE-----------KTHTNETIDFDETYGVNVQFEESDDEDTGDVYGEVQEEGDVEEEEEGEEAAFDAT-----LHANLSEEDRNKGDVGLHPREIDAFWIQRKISKFYPDDPNMAQSKAKDVLEILKTAGDDREAETKLVMLLDVSHFEFIKTLRQHRQMILYCTMLAQAQTSNEKKKIDKQMSADAELSVILKMLQATD-QDDIVSEERARRQQARQTRVAADIEAMDVEEEEEVGPVQNLYLEDLVFSQGSHLMANKICQLPDGSYRKQRKGYEEVHVPALKPKPFDNDETLVSIDRLPKYAQPAFERFKSLNRIQSRLVNAAIETDQNLLLCAPTGAGKTNVALLTIMREIGKHVNADGTINSDDFKIIYIAPMKSLAQEMVGTFSQRLASYNLRVQELTGDHQLTREQIASTQVIVCTPEKWDIITRKGGEKTYTQFVRLLIFDEIHLLHDDRGPVLESLVARTIRTIESTQE--DVRLVGLSATLPNYEDVAVFLRVDPKEGLFFFDNSFRPVPLDQQFIGITEKKAIKRFQLMNDIVYEKVIEHAGKNQVLVFVHSRKETGKTARTIRDMCLEKDTLGLFMKEGSASTIVLRQEAEQVKSSELKDLLPYGFAIHHAGMNTVDRKLVEDLFNDRHIQVLISTSTLAWGVNLPAHTVIIKGTQIYSPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGIMITNHSELRYYLSLMNQQLPIESQFISKMADNLNAEVVLGTVHNIKEAVDWLGYTYLYIRMLRNPTLYGVSHDALKEDPLLQQRRKDLVHTAACILDKNGLLKYDRKTGNLQVTELGRISSHYYITHESMATYNQLLKPTLSEIELFRVFSLSSEFKYLTVREEEKLELMKLLERVPIPIKESIEEPSAKVNVLLQAYISQLKLEGFALMVDMVFITQSAGRLMRALFEICLHYGWAQLVDKSLALCKMVDKRMWQSMTPLRQFRKIPEQVIKKIEKKNFPFERLYDLNHNEIGELLRLPKMGKPIHKHIRQFPRLELSVHIQPITRSTLKVELTITPDFQWEEKLHGHSEAFWILVEDVDSEAVLHHEYFLLKSKFATDEHLVKFFVPVFEPLPPQYFIRVVSDRWIGAETQLPVSFRHLILPERYPPPTELLDLQPLPISALRNPKFETLYSKKFAIFNPIQTQVFNSIYNSDDNVFVGAPTGSGKSICGEFAVLRMFSQNPEGRCVYVAPLDALAQQIYNDWHTKFAGVLGKKVVLLTGETGTDLKLLAKGNIVISTPDKWDVLSRRWKQRKNVQNVNLFIVDELHLI-SGEIGPVLEVICSRMRYISSQLERNIRIVALSSSLSNAKDIAQWLGCPTSAFFNFHPNVRPVPLELHIQGFNVSHNASRIMAMAKPTYQAVMKHSSKRPVLVFVPSRKQTKMTAIDILTCAAAEMQVGADDKPISRFLHVTEEDLGPFLEKISDLTLKETLANGVGYLHEGLTETERKLVEQLFSSGAVQVLVVARSLAWGINVAAHLVIVMDTQYYDGKMHSYEDYPVTDVLQMIGKANRPMLDKEGKAVIMCQSSKKEFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTIENKQDAVDYLTWTFIYRRMTQNPNYYNLQGVTHRHLSDHLSEVVENTINDLEQSKCINIEDDFDVHPLNLGMIAAYYYINYTTIELFSMSLNNKTKIKGLIEIVANAAEYENLPIRHGETAILKQLGS--RLPNKLTNAKFNDPHVKTNLLLQAHLSRMPL-SAELQSDTEDILNKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSPLKQLPHF-AADIIKRCQEKNLESIFDIMEMEDKDRTELLALNESEMADVARFCNRYPNIELTYEVLDKESIHSGSNINVTVTLEREDEIIGPVIAPMFPQKREEGWWVVIGDPKSNSLLSIKRLTLQQKAKVKLDFMAP-AHGRYNYVIFFMSDAYMGCDQEYKFSVDV 2133

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. TrEMBL
Match: A0A3B3T081 (Small nuclear ribonucleoprotein 200 (U5) OS=Paramormyrops kingsleyae OX=1676925 PE=4 SV=1)

HSP 1 Score: 2332.37 bits (6043), Expect = 0.000e+0
Identity = 1168/2157 (54.15%), Postives = 1579/2157 (73.20%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXX----XXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV---ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVS--KSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  KMG R  + +P  +EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  + DKER++  ++LLG    DT+Y+ LV+L  K+TDY   K   N +         ++  E D+++ +E+       + S+ D  GVEAD   TL  +  AAG +                      A  + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR+++ MI YCT L  +Q+  E+ +I  +M+ D   +++L  L+  + KEDI+  ER+R+ + R +++  D+E  D +   +     +LDL+++ F+QGSH M NK C+LPDGSFRK + GY  V VPA KPKP   DE L+    LP Y +AAFE  K LNRIQSK++K A+E+DEN+LLCAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SFS+RL SY + VA L+GD  L +EEIN TQ+IVCTPEKWDII+RK  E+TYTQLV+L+IIDEIHLLHD+RGPVLE++VART+R ++ +    D+R++GLSATLPN ED+A  + VD  RGLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ++ KLAD LNAEIV+G V+N  ++++WL YTYLY+RM +NP+LYGV   +  L  DP L+    +L++TA  +L+K  ++ +DKR+G F   ++GRIA+++Y T++++    + LK ++ +IE+F+VFS  +EFRNITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQAYISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   +  CK +++RMW    PLRQF+K+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+HQ PKL+L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR  SD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+  +  + RCVY+T +  LA+  + +W + F   L K V+ LTG T+ D K + K  IIVST + WD+LSRRWK++K +QN+ LFIVD+ HLIG + NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+DV  WL C  TAT+NF+P+VR  PL++ IQ FN++H  TRL +M+KPVY +I++ SP  PV+VFVP+ +QT   A  ++ +  +D   + F   +E  ++ ++  +++  L ETL+ GVG++HE LS  ER ++ +LFSS ++Q++V S +LCW     A+LVIVMDTQ YNGK   Y DY   D++QMVG+AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH LHDHFNAEIVTKT+ENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVENTL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +K+R L+E+I NA E++++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K+VRLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+PHF     ++RC   GV+++FD+ME+EDE++  L+   D ++ DVARF   YPNI+L+YEV+  +S+ +GG V VQ+ L R+E+    V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP  +G + YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTKMGDRSQRTRPQMLEERRAKRRKRDEDRHDINKMKGFTLLSEGIDEMVGIVYKPKTKETRETYEVLLSFIQAALGDQP-RDILCGAADEVLAVLKNEKMRDKERRREVEQLLGPA-DDTRYHVLVNLGKKITDYGGDKELQNMDDNIDETYGVNVQFESDEEEGDEDQFGEVRDEGSDEDSEGVEADIGLTLTANLGAAGDVMS--------------------AKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRRMILYCTMLASAQSEAEKKRITEKMEADQDLSKVLYQLQETE-KEDIIREERSRRERVRKSRVDNDLEAMDLDAGESLAPRQLLDLEDLAFSQGSHFMANKRCQLPDGSFRKQRKGYEEVHVPALKPKPFAEDEVLLATEKLPKYAQAAFEGFKNLNRIQSKLFKAAMETDENLLLCAPTGAGKTNVALMAMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFSKRLASYGITVAELTGDHQLCKEEINATQVIVCTPEKWDIITRKGGERTYTQLVRLIIIDEIHLLHDDRGPVLESLVARTIRNVELTQE--DVRLLGLSATLPNYEDVATCLRVDPARGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVGKLADMLNAEIVLGNVQNAKDAVNWLGYTYLYVRMLRNPTLYGVSHDDRAL--DPLLERRRLDLVHTAGCLLDKNSLVKYDKRTGSFQVTDLGRIASHFYVTHDSIHTYNQLLKPTLSEIELFRVFSLSSEFRNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAYISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLARGWAQLTDKTMNLCKMIDKRMWLSMSPLRQFRKLPEEVIKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHQFPKLDLAVHLQPITRSTLKVELTITPDFQWDDKVHGSSEAFWILVEDVDSEVILHHEYFLLKSKYAQDEHLVTFFVPVFEPLPPQYFIRISSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNAVYNSDDNVFVGAPTGSGKTICAEFAILRMLLHNAEGRCVYITPMEALAEQVFVDWHQKFQDTLNKKVVLLTGETSTDLKLLGKGDIIVSTPDKWDILSRRWKQRKNVQNVSLFIVDETHLIGGE-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSTTATFNFHPNVRPVPLELHIQGFNVSHTQTRLLSMAKPVYHSIIRHSPTKPVLVFVPSRRQTRLTAIDILTFCAADVVAQRFLHCAEKDLAPFLEKLTDNTLKETLANGVGYLHEGLSATERRIVEQLFSSGAVQVVVASRSLCWGTNISAHLVIVMDTQYYNGKIHAYVDYPIYDVLQMVGKANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTVENKQDAVDYLTWTFLYRRMTQNPNYYNLQGMSHRHLSDHLSELVENTLHDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKIRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAVRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTCDH-IKRCTDKGVESIFDIMEMEDEERSVLLQLSDGQMADVARFCNRYPNIELSYEVAEKESIKSGGPVLVQVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDPKSNSLISIKRLTLQQKAKVKLDFVAP-ATGIHNYTLYFMSDAYMGCDQEYKFSVDV 2125

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Cavefish
Match: snrnp200 (small nuclear ribonucleoprotein U5 subunit 200 [Source:NCBI gene;Acc:103030392])

HSP 1 Score: 2313.88 bits (5995), Expect = 0.000e+0
Identity = 1162/2154 (53.95%), Postives = 1573/2154 (73.03%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXXXSE--SDDG-GVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFG-ALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKS--VSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  KMG +  + KP  +EE++ KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ +   L +    +I     DE+L  LKN  + DKER++  ++LLG    DT+Y+ LV+L  K++DY   K   N + +      + +  + +EEE D     +  E  SDD  G EAD   TL+ +   AG +                         + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR+++ MI YCT L  +Q+  E+ KI A+M+ D   +++L  L+  + KEDI+  ER+R+ + R +++  D+E  D +   +  +  +LDL+++ FTQGSH M NK C+LPDGSFRK + GY  V VPA KPKP   DE LV +  +P Y +AAFE  KTLNRIQSK++KT +E+D N+L+CAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SF +RL SY + V+ L+GD  L +EEIN TQIIVCTPEKWDII+RK  E+TYTQLV+L+IIDEIHLLHD+RGPVLE+++ART+R ++ +   +  R++GLSATLPN ED+A  + VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ++ KL D LNAE+V+G V+N+ ++++W+ YTYLY+RM +NP+LY V  +    DP L+    +L++TAA++LEK  ++ +DKRSG F   ++GRIA+++Y T+E++    + LK ++ +IE+F+VFS  +EFRNITVREE+K+E++KLLE VP+P+KE  E+P  KIN LLQAYISQLKLE F L +D  Y++QSA RLMRA+FE+ L + WA LT   +  CK +++RMW    PLRQF+K+P E+ KK+EKK+ PF+RL D  H+E+GEL+   KMGKTI+KY+HQ PKL+L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +ES+Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+  +  + RCVY+T +  LA+  + +W + F  AL K V+ LTG T+ D K + K  II+ST + WD+LSRRWK++K +QN+ LFIVD+ HLIG + NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+DV  WL C  TAT+NF+P+VR  PL++ IQ FN++H  TRL +M+KPVY +I+K SP+ P +VFVP+ +QT   A  ++ +  +D   + F   +E  ++ ++  +S+  L ETLS GVG++HE LS  E  ++ +LF+S +IQ++V S +LCW     A+LVIVMDTQ YNGK   Y DY   D++QMVG+AN    DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH LHDHFNAEIVTKT+ENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVENTL DLE SKCI+++D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +K+R L+E+I NA E++++P+RH ED +L ++ Q +   ++   + +DP  K N+LLQA+LSR+ + +AEL+ D   IL K+VRLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS L+Q+PHF     ++RC   GV+++FD+ME+EDE++ AL+   D ++ DVARF   YPNI+L+YEV+    + +G  V VQ+ L R+E+    V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP   G + YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTKMGDKSQRTKPQMLEERRAKRRKRDEDRHDINKMKGFTLLSEGIDEMVGIVYKPKTKETRETYEILLSFIQAALGDQP-RDILCGAADEVLAVLKNEKMRDKERRREVEQLLGPT-DDTRYHVLVNLGKKISDYGGDKELQNMDENIDETYGVNVQFESDEEEGDEDQYGEVREEGSDDSEGEEADVGCTLSANLGTAGDVM--------------------TTKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRRMILYCTMLASAQSEAEKEKIIAKMEADQDLSKVLYQLQETE-KEDIIREERSRRERLRKSRVD-DMESMDIDRSESVAARQLLDLEDLAFTQGSHFMANKRCQLPDGSFRKQRKGYEEVHVPALKPKPFSDDETLVAVEKMPKYAQAAFEGFKTLNRIQSKLFKTTMETDGNLLVCAPTGAGKTNVALMAMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLASYGITVSELTGDHQLCKEEINATQIIVCTPEKWDIITRKGGERTYTQLVRLIIIDEIHLLHDDRGPVLESLIARTIRNVELTQEEV--RLIGLSATLPNYEDVATCLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVGKLPDMLNAEVVLGNVQNVKDAVNWIGYTYLYVRMLRNPTLYAVSHDERSTDPYLEQRRMDLVHTAATVLEKNNLVKYDKRSGSFQVTDLGRIASHFYITHESIMTYNQLLKPTLSEIELFRVFSLSSEFRNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAYISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLGRGWAQLTDKTMNLCKMIDKRMWQSMSPLRQFRKLPEEVIKKIEKKSFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHQFPKLDLAVHLQPITRSTLKVELTITPDFQWDDKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNAAFESLYQNKFPFFNPIQTQVFNAVYNSDDNVFVGAPTGSGKTICAEFAILRMLLHNTEGRCVYITPMEALAEQVFVDWHQKFQEALNKKVVILTGETSTDLKLLGKGDIIISTPDKWDILSRRWKQRKNVQNVSLFIVDETHLIGGE-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSTTATFNFHPNVRPVPLELHIQGFNVSHTQTRLLSMAKPVYHSIMKHSPSKPTLVFVPSRRQTRLTAIDILTFCAADVVPQRFLHCTEKDLAPFLEKLSDATLRETLSNGVGYLHEGLSSTECKIVEQLFNSGAIQVVVASRSLCWGTNISAHLVIVMDTQYYNGKIHAYVDYPIYDVLQMVGKANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTVENKQDAVDYLTWTFLYRRMTQNPNYYNLQGMSHRHLSDHLSELVENTLQDLEQSKCISVEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKIRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLNSP-KFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEDILSKAVRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLRQLPHFTTEH-IKRCTDKGVESIFDIMEMEDEERTALLQLSDVQMADVARFCNRYPNIELSYEVADKDYIKSGSPVLVQVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDPKSNSLISIKRLTLQQKAKVKLDFVAP-VVGVHNYTLYFMSDAYMGCDQEYKFSVDV 2123

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Cavefish
Match: ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:NCBI gene;Acc:100332599])

HSP 1 Score: 1261.9 bits (3264), Expect = 0.000e+0
Identity = 691/1789 (38.62%), Postives = 1063/1789 (59.42%), Query Frame = 1

Query: 1324 KNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEY--AGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNV-PVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLLKEK--FKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALS--DKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIK-DDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSD-PRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNE----------------------------PKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSK---------------------------SVSAGGQVSVQIHLAR------DEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLSSPTEK--VSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            K   F  GS ++      LP+G  R+    +  V +P  +P P+   E  V I++L    +  F+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI +H+   G IRKD FKIVY+APMK+L  EM N FS+RL+   + V  L+GD  L++ EI  TQ++V TPEKWD+++RKS  +   +Q+V+L+I+DE+HLLH++RGPVLE++VART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+ + GLF FDS +RPVP+ Q ++G+     ++++  M ++ Y+KV+E   AG HQV++FVH+R  TV TA ++ E   NR     F  D+       ++ + + +N  L+++ P GF +HHAG+   DR  +E +F+  +++VLV T+TLAWGVNLPAH VIIKGTQ+Y   +G   +L  LDVMQ+FGRAGRPQ+D  G G +IT  ++L++YL+LL +Q PIESQ  + LADNLNAE+                                       DP L+ + + L+  A   L+KA MI F++R+G F S ++GR A+++Y    T++   +       D ++  + SK  EF  + VR+E++ E++ LL N   +P   G E+   KIN LLQ Y+S+ +++ F+L SD +Y++Q+AAR+MRA+FE+ L K+W ++T  +L  CK +++R+W  + PLRQF  +P  +  +LE++ +  D+L D +  E+G ++++  +G  + + +HQIP + ++  +QPITR+ ++V LTITPDF W  + HGS  + +W++VED ++++I H EYFLL++K     +   + F + I++P+P  YYIRAVSD+W+G E    I F +++LPE++ P TELLDLQ LP  AL N EYES+Y  K + FN IQTQ F +LY++D NV +GAPTGSGKT+ AE+AI R+F+    A+ VY+  L  L + R  +W ++    LG+ V++LTG+   D ++I++A +IV+T E WD +SR W+ +  +Q + + I+D++HL+G +  G  LEVI SRT ++SS    P+R++GLS +L NARD+ +WL       +NF PSVR  PL++ IQ F   H   R+A+M+KPV+Q I   SP  PV++FV + +QT   A  L+ +  +  D K +    E  +++ +  + +  L  TL+ G+G  H  L   +R  + ELF +  IQ+L+ + TL W +   A+LVIV  T+ Y+GK   Y DY       + G            +++    KKDF +KFL+EP P+ES L   L DH NAEI   T+ +KQDA+DY+TWT+ + R+  NP+YYNL  ++H  ++  LS LVE +L DLE S C+ I+ D+  +  +  G IA++YY+ + T+ MF   LKP+  V+ LL ++ +A E+ +LP+RH ED + + + Q  RLP+  +    D   TK ++LLQA+ SR  +  ++   D   +L  ++R+ QA +DV ++  WL  AL+   L QMI QA+W  DS L  +PH  +                            P+L+  C+  G + +F  M  E+ Q          ++     F    P ++++ +V                              V A  +  +Q+ L R           S   A  FP  ++E W+LV+GE  +  L++IK +     +  VSL F  P ++G   YTLY MSDSYLG DQ+Y   +NV
Sbjct:  413 KTSAFIGGSKML------LPEGIRRENNKMFEQVEIPPNEPMPIGFQEKPVYISELDEIGQLVFKGMKRLNRIQSIVFETAYNTNENLLICAPTGAGKTNIAMLTVLHEIRQHLQPGGVIRKDQFKIVYVAPMKALAAEMTNYFSKRLEPLGISVKELTGDMQLTKGEILRTQMLVTTPEKWDVVTRKSVGDVGLSQIVRLIILDEVHLLHEDRGPVLESLVARTLRQVESTQSMI--RILGLSATLPNYLDVASFLHVNPYIGLFFFDSRFRPVPLGQTFVGVKTTSKIQQLHDMEEVCYDKVLEQIRAG-HQVMVFVHARNSTVRTAMSLIEMAKNRGESSFFQVDQGPDYGHCEKQVQRSRNKQLREMFPDGFGIHHAGMLRQDRTLMENMFSRGYLKVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGAMVDLGILDVMQIFGRAGRPQFDKYGEGTIITTHDKLSHYLTLLTQQNPIESQFHASLADNLNAEM---------------------------------------DPGLELYRKELVVEAGRKLDKARMIRFEERTGYFASTDLGRTASHFYIKYNTIETFNELFNAQKTDADILSIVSKAEEFEQVKVRDEEQEELEALLYNFCQLPAAGGVENGYGKINILLQTYVSRGEVDNFSLISDLSYVAQNAARIMRALFEIALRKRWPAMTYRLLNLCKVIDKRLWGWAHPLRQFTTLPTSVLSRLEERKLTVDKLKDMRKDEIGHMLHHVNIGLKVKQCVHQIPAILMEASIQPITRTVLRVRLTITPDFRWNDQVHGSVGEPWWLWVEDPINDHIYHSEYFLLQKKQVVSGEPQQVVFTIPIFEPMPSQYYIRAVSDRWLGSEAVCIINFQHLILPERHPPHTELLDLQPLPVLALGNREYESLY--KFTHFNPIQTQIFHTLYHTDTNVLLGAPTGSGKTIAAEMAIFRVFNKYPTAKAVYIAPLKALVRERIEDWKIRIEEKLGRKVVELTGDVTPDMRAIAQADLIVTTPEKWDGVSRSWQNRSYVQKVAILIIDEIHLLG-EDRGPVLEVIVSRTNFISSHTSKPVRVVGLSTALANARDLADWLGIGQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPVFQAIRSHSPAKPVLIFVSSRRQTRLTALDLIAFLATEDDPKQWLHQDEREMTDIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKIQVLIATSTLAWGVNFPAHLVIVKGTEYYDGKTHRYVDYPITGSEVLAG------------LMLLHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAAGTVTSKQDAMDYITWTYFFRRLVMNPSYYNLDDINHETINKFLSNLVEKSLRDLECSYCMEIQEDERTIEPLTYGRIASYYYLKHQTVRMFKERLKPDLPVQELLSILTDAEEYAELPVRHNEDQLNSELAQ--RLPLQVNPHSYDSAHTKTHLLLQAHFSRAQLPCSDYGTDTKTVLDNAIRVCQALLDVAANEGWLVSALSICNLVQMIVQARWLHDSSLITLPHIEKQSLYLFRRWSSKGGQGGGRGYQGPIEALPELIAACD--GREEIFTAMVKEELQP--------HQISQAWAFLSHLPVVEVSLKVKGWWEGCEEQTERALPTNVTSFREQSSWLPVHADQEYVLQVSLQRINMGRQRRKQDSKAQAPRFPKPKDEGWFLVLGEVEKKELLAIKRVGYVRNRSVVSLAFYTPEQTGKCIYTLYLMSDSYLGLDQQYDIHLNV 2126

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Cavefish
Match: hfm1 (helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-061207-43])

HSP 1 Score: 292.738 bits (748), Expect = 1.218e-79
Identity = 226/765 (29.54%), Postives = 383/765 (50.07%), Query Frame = 1

Query: 1492 PSYVKAA-----FEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSRE-EINETQIIVCTPEKWDIISRKSSEKTYTQLVKX-XXXXXXXXXXXXRGPVLEAIVAR-----TMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRG-LFKFDSSYRPVPMEQEYLGI---NERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-----VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTL--SKKWASLTLSVLESCKEVEQRMWACSCPL-RQFKKVPWEITKKLEKKNI-PFDRLIDQKHHELGELVNNH-KMGKTIYKYIHQIPKLNLKIHLQP-ITRSTMKVELTI 3705
            P +++AA     F++    N +QSK     L + +N + CAPTG+GKT +  L ++R +      + T    + K VY+AP+K+L ++   ++  +     L    L+GD+ +    EI +  +I+ TPEKWD ++RK       Q V+L LI +   +    RGP LE +V+R     +    +S  ++  MR V +SAT+PN  DIA+++  D+      + D S+RPV + +  LG    N +   K    +N  +   +  Y+ +   L+F  +RK    +A       L +D   +   D +     L +    + +  L+DL+  G   HHAG++ +DR  VE+ FT   + VL +TSTLA GVNLPAH+V+IK T  Y    G   E S  D++QM GRAGRPQ+DT    +++T       YL  ++    IES L + L ++LNAEIV+ T+ +++ ++DW+R T+LYIR  KNP+ YG  + L D   ++   + L     + L   ++I  D+        E G++ A Y    +TM    K L  +    E+ ++ SK  EF ++ +R  +K  +  L  +     +  P++   +    K+NCL+QA +  L ++ F L+ DT  I +S  R+ + + E     SK+  S  L+ L   K    ++W  S  + +Q  K+   +   +    +  F ++      EL  +VN H   G  I + + ++PK  +++   P  + ST ++ +T+
Sbjct:  224 PIHIQAAKFRGVFKEFPYFNYVQSKALDDILYTSKNFVACAPTGSGKTVLFELAIIRLL-----METTEPWHNVKAVYMAPIKALCSQQYENWKLKFGPLGLNCKELTGDTEIEDVFEIQDAHLIMTTPEKWDSMTRKWKNNCLLQSVQLFLIDEVHVVKDSTRGPTLEVVVSRMKTIHSYTVAESPDASTRMRFVAVSATIPNICDIADWLSNDQGPATCLEMDESHRPVKLRKVVLGFPFGNSQNEFKFDLSLNYKMASVIQTYSDQKPTLVFCSTRKGVQQSATV-----LAKDARFIMSIDHRQR---LMKYASSILDAKLRDLIMCGVGYHHAGVSLSDRKVVEDAFTAGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYA--GGSCEEYSEADMLQMIGRAGRPQFDTSATAVIMTRIQTREKYLQFISGSETIESSLHTNLVEHLNAEIVLHTISDVNMALDWIRSTFLYIRALKNPTHYGFSSEL-DKCGIETKLQELCLKNLNSLASYQLITMDEDIN-IKPTESGKLMARYCVAFDTMKQFSK-LTGTENLAELIEMMSKGKEFSDVQLRVNEKRTLNTLNIDKNRVTIRYPMEGKIKSKDMKVNCLIQAQLGNLPIQEFGLTQDTGKIFRSGVRISKCLAEFLSHHSKQNFSAQLNSLILAKCFRAKLWEDSPYVSKQLDKIGLSLATAMVNAGLTSFSKIEATNPRELELIVNRHPPFGNQIKEAVSKLPKYEIRLEQLPKYSVSTAEILVTV 970

HSP 2 Score: 271.552 bits (693), Expect = 5.461e-73
Identity = 180/662 (27.19%), Postives = 323/662 (48.79%), Query Frame = 1

Query: 4060 KKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNR----QDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNK-SISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYM-------SSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQT----FNITHNATRL-AAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYA-----LSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKG-VSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRI-----KQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLS--SNRWLGPALAAMELAQMITQAQW 5952
            K+  +FN +Q++  + +  + +N    APTGSGKTV  E+AI+RL         + + VY+  +  L   +Y  W   FG LG    +LTG+T +++   I  AH+I++T E WD ++R+WK    +Q++QLF++D++H++     G TLEV+ SR + +       S    T +R + +S ++ N  D+ +WL               HRP+ +        F  + N  +   +++  +   I   S   P +VF  T K  ++ A +L   A     +  ++   + + +I+   +R++        + CGVG+ H  +S+++R ++ + F++  + +L  + TL   +   A+LV++  T  Y G  C  ++YS  D++QM+GRA     D  A +VIM +   ++   +F+     +ES L   L +H NAEIV  TI +   A+D++  TFLY R  +NP +Y     +    +   L EL    L  L + + I + +DI++     G +   Y + + T++ FS  L     +  L+E++    EF D+ LR  E   L  +     + ++R P+  + ++     K N L+QA L  +PI+   L +D  +I    VR+ +   + LS  S +     L ++ LA+      W
Sbjct:  237 KEFPYFNYVQSKALDDILYTSKNFVACAPTGSGKTVLFELAIIRLLMETTEPWHNVKAVYMAPIKALCSQQYENWKLKFGPLGLNCKELTGDTEIEDVFEIQDAHLIMTTPEKWDSMTRKWKNNCLLQSVQLFLIDEVHVVKDSTRGPTLEVVVSRMKTIHSYTVAESPDASTRMRFVAVSATIPNICDIADWLSNDQGPATCLEMDESHRPVKLRKVVLGFPFGNSQNEFKFDLSLNYKMASVIQTYSDQKPTLVFCSTRKGVQQSATVLAKDARFIMSIDHRQRLMKYASSILDAKLRDL--------IMCGVGYHHAGVSLSDRKVVEDAFTAGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYAGGSC--EEYSEADMLQMIGRAGRPQFDTSATAVIMTRIQTREKYLQFISGSETIESSLHTNLVEHLNAEIVLHTISDVNMALDWIRSTFLYIRALKNPTHYGFSSELDKCGIETKLQELCLKNLNSLASYQLITMDEDINIKPTESGKLMARYCVAFDTMKQFS-KLTGTENLAELIEMMSKGKEFSDVQLRVNEKRTLNTLNIDKNRVTIRYPM--EGKIKSKDMKVNCLIQAQLGNLPIQEFGLTQDTGKIFRSGVRISKCLAEFLSHHSKQNFSAQLNSLILAKCFRAKLW 885

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Cavefish
Match: polq (DNA polymerase theta [Source:NCBI gene;Acc:103039702])

HSP 1 Score: 119.013 bits (297), Expect = 5.343e-26
Identity = 133/474 (28.06%), Postives = 224/474 (47.26%), Query Frame = 1

Query: 1579 ENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSE---RLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWD-IISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTM--------RAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINE----------RKAVKRIELMND------LVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLV---------LQQDLDKVK------NHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQL-PIESQLISKLADNLNA-------EIVMGTVRNIHESI 2847
            +N++  APT AGKT V+ L +++ + +      T RK  F + +++  +  +  + N F E   R++ Y    +   G S L         + VCT EK + +I+R   E     L  +++ +   L    RG +LE ++ +          R    ++++  ++IVG+SATLPN + +A ++  +    L+  D  YRPVP+  E++ I            R+    + +  D      L +E V  +AG H  L+F  S+      A +I      R+   L+ ++K++ + V         LQ  + ++K      +  L+  +P+G A HHAGL + +R+ +E  F    I+VL +TSTL+ GVNLPA  VII+ T V+    G    L  L   QM GRAGR   DT G  +++  E E    +SL+   L PI S L+ +  + +         EI++G V +  E +
Sbjct:  286 KNLVYSAPTSAGKTLVSELLILKRVLE------TRRKAIFILPFVSVAREKMFYLQNVFQEAGVRVEGYMGSTSAAGGFSALD--------VAVCTIEKANGLINRLIEEDRMDLLGIVVVDELHMLGDSGRGYLLELLLTKIQYIATKTKERCTDKAYTD-GVQIVGMSATLPNLDLLARWLSAE----LYHTD--YRPVPL-MEWVKIGTQIYDGSMTLIRQFTPALPVKGDDDHIVSLCFETV--HAG-HSALLFCPSKNWCEKLADSIA-----REFYNLYHKEKQSESGVQSVSLNLEGLQDVVAQLKRSPAGLDQVLQRTVPWGVAFHHAGLTFDERDILEGAFRQGFIRVLAATSTLSSGVNLPARRVIIR-TPVF---NGHL--LDILTYKQMVGRAGRKGVDTIGESVLVCKEAERMKGVSLIQGSLKPISSCLVKREGEGVTTSMLRAILEIIVGGVASTPEEV 723

HSP 2 Score: 85.5001 bits (210), Expect = 7.017e-16
Identity = 102/447 (22.82%), Postives = 200/447 (44.74%), Query Frame = 1

Query: 3994 LLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFE-SLYNSDENVFIGAPTGSGKTVCAEIAIM-RLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLET---------PIRIIGLSYSLTNARDVGEWL--DCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPV-----------YQTILKLSPNSPVIVFVPTMKQTEEIAFLLMG--YALSDKKNFGRAS-----------EAIVSEYMRNIS--NEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLI---QMVGRANHASMDD-ARSVIMCQ 5205
            LL    LP   L  E+Y+S+  K+M  +   Q +C         +N+   APT +GKT+ +E+ I+ R+   R+ A  +++     +A+ +       F   G  V    G+T+      S   + V T E  + L  R  ++  +  + + +VD+LH++G    G  LE++ ++ +Y++++ +           ++I+G+S +L N   +  WL  + +HT   ++ P      + I  Q ++ +    R    + PV           ++T+         ++F P+    E++A  +    Y L  K+    +            + +V++  R+ +  +++L  T+  GV F H  L+ +ER+++   F    I++L  + TL   +   A  VI+  T V+NG          +D++   QMVGRA    +D    SV++C+
Sbjct:  247 LLSSWGLPKPVL--EKYQSLGVKQMFEW---QAECLTLGKVLEGKNLVYSAPTSAGKTLVSELLILKRVLETRRKA--IFILPFVSVAREKMFYLQNVFQEAGVRVEGYMGSTSAAG-GFSALDVAVCTIEKANGLINRLIEEDRMDLLGIVVVDELHMLGDSGRGYLLELLLTKIQYIATKTKERCTDKAYTDGVQIVGMSATLPNLDLLARWLSAELYHT---DYRPVPLMEWVKIGTQIYDGSMTLIRQFTPALPVKGDDDHIVSLCFETV---HAGHSALLFCPSKNWCEKLADSIAREFYNLYHKEKQSESGVQSVSLNLEGLQDVVAQLKRSPAGLDQVLQRTVPWGVAFHHAGLTFDERDILEGAFRQGFIRVLAATSTLSSGVNLPARRVIIR-TPVFNGH--------LLDILTYKQMVGRAGRKGVDTIGESVLVCK 670

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Cavefish
Match: helq (helicase, POLQ like [Source:ZFIN;Acc:ZDB-GENE-060503-421])

HSP 1 Score: 98.5969 bits (244), Expect = 4.983e-20
Identity = 83/278 (29.86%), Postives = 122/278 (43.88%), Query Frame = 1

Query: 1960 RGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFK----------FDSSYRPVPMEQEYLGINERKAVKRIELMN----DLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLL----PYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVM------QMFGRAGRPQYDTKGVGIMITNENE 2721
            RG +LE  +A+ +      + N   +I+G+SATL N  D+  F+  + +   F+           DS Y   P E+E    +   A K    M     D +   V E   K   LIF  ++K   N A  I  K L+ D    FL  ++     L  +L    N  L  +L    P+G A HH+GL   +R  VEE ++   + +L  TSTLA G+NLPA  VI++   V             +D +      QM GRAGR   D+ G  I+I  + +
Sbjct:  346 RGAILEMTLAKVL------YINKSTQIIGMSATLGNIGDLQSFLRAENYTNDFRPVELKEYVKLRDSIYEVKPKEEECFRFSRLLAFKYSSGMQKMDPDHIIALVTEVIPKQSCLIFCATKKNCENVAGMIC-KYLHTD----FLMHREGEKATLLAELRNSGNGSLCPVLQRTVPFGLAYHHSGLTSDERKLVEEAYSSGVLCLLACTSTLAAGINLPARRVILRSPYV------------GIDFLKRSQYKQMVGRAGRAGIDSVGESILILQDRD 600

HSP 2 Score: 97.8265 bits (242), Expect = 8.581e-20
Identity = 106/421 (25.18%), Postives = 180/421 (42.76%), Query Frame = 1

Query: 4123 ENVFIGAPTGSGKTVCAEIAIMR-LFSNRQDARCV--YVTALNDLAQLRYTEWMKTFG-ALGKTVIKLTGNTNM--DNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNP-------SVRH-----RPLDIEIQTFNITHNATRLAAMSK--P--VYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAIVSEYMRNISN----EILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLI------QMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHD 5286
            +N+    PT  GKT+ AEI I + L   R+DA  +  YV  + +         + +FG  L   V +  G+       K  S   + ++T E    L     +   + NI L +VD+LH++G    G  LE+  ++  Y++       +IIG+S +L N  D+  +L   +  T +F P        +R      +P + E   F+        + M K  P  +   + ++ P    ++F  T K  E +A ++  Y  +D        +A +   +RN  N     +L  T+  G+ + H  L+ +ER L+ E +SS  + +L  + TL   I   A  VI            +   Y  +D +      QMVGRA  A +D    S+++ Q   KD ++K +    P+E    + LHD
Sbjct:  226 KNLIYSLPTSGGKTLVAEILIFKELLCRRKDALLILPYVALVQE-----KVRGLASFGIELDFMVEEYAGSKGRFPPVKRRSSNSLYITTIEKGHSLVNSLIEANRLDNIGLVVVDELHMLGDGSRGAILEMTLAKVLYINKS----TQIIGMSATLGNIGDLQSFLRAENY-TNDFRPVELKEYVKLRDSIYEVKPKEEECFRFSRLLAFKYSSGMQKMDPDHIIALVTEVIPKQSCLIFCATKKNCENVAGMICKYLHTDFLMHREGEKATLLAELRNSGNGSLCPVLQRTVPFGLAYHHSGLTSDERKLVEEAYSSGVLCLLACTSTLAAGINLPARRVI------------LRSPYVGIDFLKRSQYKQMVGRAGRAGIDSVGESILILQDRDKDMVRKLVSA--PMEKCYSNLLHD 622

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Sea Lamprey
Match: ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:NCBI gene;Acc:100332599])

HSP 1 Score: 933.71 bits (2412), Expect = 0.000e+0
Identity = 468/1134 (41.27%), Postives = 706/1134 (62.26%), Query Frame = 1

Query: 2032 MRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYA-GKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLID-DPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLL--KEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGK-----TVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNP 5388
            +RIVGLSATLPN  D+A F+HV+ + GLF FDS +RPVP+ Q ++G+     ++++  M+++ Y+KV+E     HQV++FVH+R  TV TA A++E   N    G F   + A      + +++ +N  +++L P GF+ HHAG+   DR+ VE LF+   ++VLV T+TLAWGVNLPAH VIIKGTQ+Y   +G + +L ALDVMQ+FGRAGRPQYDT G+GI+IT+ ++L  YL+LL +Q PIESQ  + L DNLNAE   G      E++ WL YTYLY+RMR NP  YG+ +     DP+L      ++  A   L+KA MI FD+R+G F   + GR A+++Y    T++    +    + + +V  +  K  EF  I VRE++  E+++L +    +P+  G E+   K+N LLQ YIS+  ++ F+L SD +YI+Q+AAR++R++FE  L K+W ++T  +L   K +++R+W  + PLRQF  +P    +KLE + +  D+L D   H++G ++++  MG+ I + + QIP L L+  +QPITR+ ++V L+IT DF WC + HGS  + +WI+VED  +++I H E F++  K+    +   + F + I++PLP  YY+RAVSD+W+G E    I F  ++LPE++ P TELLDLQ LP  AL +   E++Y  + + FN +QTQ F +LY+ D NV +GAPTGSGKTV AE+AI R+F+    A+ VY+  L  L + R  +W ++     GK      V++LTG+   D ++I+ A +IV+T E WD +SR W  +  ++ + L ++D++HL+G    G  LEVI SRT ++SS  E P+R++GLS +L NARD+ +WL       +NF PSVR  PL+  I  F   H   R+A M+KP +Q I   SP  PV++FV + +QT   A  L+ +   +   K +    E  +   +  + +  L   L+ G+G  H  L   +R  + ELF +  IQ+L+ + TL W +   A+LVI+  T+ ++GK   Y D+   D++QM+GRA     DD  ++VI     KKDF +KFL+EP P+ES L   L DH NAEI + TI +KQDA+DY+TWT+ + R+  NP
Sbjct:    9 IRIVGLSATLPNYLDVARFLHVNPYIGLFFFDSRFRPVPLSQTFIGVKTTNKMQQMHDMDEVCYDKVLEQVKAGHQVMVFVHARNATVRTAMALREMAKNNGEAGFFTPPQSAEYGTAFKQVERSRNKPMRELFPDGFSTHHAGMLRPDRSLVEGLFSRGLVRVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGTFVDLGALDVMQIFGRAGRPQYDTFGLGIIITSHDKLGRYLTLLTQQNPIESQFQASLQDNLNAEDEAGLATAAFEAVRWLSYTYLYVRMRANPLAYGINHSHYQADPSLHKFREQMVVDAGRKLDKARMIRFDERTGYFSPTDTGRTASHFYIKYNTIETFNDYFGPHLTESDVLSMVCKAEEFEQIKVREDELGELEQLADGYCLLPVAGGVENGYGKVNILLQTYISRGDVDCFSLVSDLSYIAQNAARIVRSLFETALRKRWPTMTSRLLALSKAIDRRLWGWAHPLRQFSALPHTTLEKLEARKMTVDKLRDMSSHDIGHMIHHVAMGQKIKQCVQQIPTLALEASIQPITRTVLRVRLSITADFTWCDQVHGSVGEPWWIWVEDPTNDHIYHSENFMILKKQVLSQEAQCVTFTIPIFEPLPSQYYVRAVSDRWLGSEAVCAINFQQLILPERHPPHTELLDLQPLPVSALGDARLEALY--RFTHFNPVQTQIFHTLYHGDGNVLLGAPTGSGKTVAAELAIFRIFNAHPGAKAVYIAPLKALVRERMEDWKVRLEPEAGKECAAARVVELTGDVTPDARAIASADLIVTTPEKWDGVSRSWHSRSYVKQVALLVIDEIHLLGDD-RGPVLEVIVSRTNFISSHTEKPVRVVGLSTALANARDLADWLAIKQVILFNFRPSVRPVPLEAHIHGFPGQHYCPRMATMNKPTFQAIRTHSPAKPVLIFVSSRRQTRLTALDLIAFLAGEDNPKQWLHTDETEMEHIISTVKDSNLKLCLAFGIGMHHAGLHERDRRTVEELFVNTRIQVLIATSTLAWGVNFPAHLVIIKGTEYFDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVIFVHDLKKDFYKKFLYEPFPVESSLLEVLADHLNAEITSGTITSKQDAMDYITWTYFFRRLIMNP 1139

HSP 2 Score: 300.056 bits (767), Expect = 9.459e-84
Identity = 182/468 (38.89%), Postives = 263/468 (56.20%), Query Frame = 1

Query: 1510 AFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKS------YNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNP 2895
            A  +    N +Q++++ T    D N+LL APTG+GKT  A L + R    H            K VYIAP+K+LV E    +  RL+          +V  L+GD       I    +IV TPEKWD +SR    ++Y + V LL+IDEIHLL D+RGPVLE IV+RT     SSH+   +R+VGLS  L N  D+A+++ + K   LF F  S RPVP+E    G   +    R+  MN   ++ +  ++    VLIFV SR++T  TA  +       D    +L   +     ++  +  VK+ +LK  L +G  +HHAGL   DR  VEELF +  IQVL++TSTLAWGVN PAH+VIIKGT+ +      + +    DV+QM GRAGRPQ+D +G  ++  ++ +  +Y   L E  P+ES L+  LAD+LNAEI  GT+ +  +++D++ +TY + R+  NP
Sbjct:  687 ALYRFTHFNPVQTQIFHTLYHGDGNVLLGAPTGSGKTVAAELAIFRIFNAHPGA---------KAVYIAPLKALVRERMEDWKVRLEPEAGKECAAARVVELTGDVTPDARAIASADLIVTTPEKWDGVSRSWHSRSYVKQVALLVIDEIHLLGDDRGPVLEVIVSRT--NFISSHTEKPVRVVGLSTALANARDLADWLAI-KQVILFNFRPSVRPVPLEAHIHGFPGQHYCPRMATMNKPTFQAIRTHSPAKPVLIFVSSRRQTRLTALDLIAFLAGEDNPKQWLHTDETE---MEHIISTVKDSNLKLCLAFGIGMHHAGLHERDRRTVEELFVNTRIQVLIATSTLAWGVNFPAHLVIIKGTEYFDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVIFVHDLKKDFYKKFLYEPFPVESSLLEVLADHLNAEITSGTITSKQDAMDYITWTYFFRRLIMNP 1139

HSP 3 Score: 162.54 bits (410), Expect = 2.694e-40
Identity = 167/662 (25.23%), Postives = 281/662 (42.45%), Query Frame = 1

Query: 4546 IRIIGLSYSLTNARDVGEWLDCH-HTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTIL-KLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRA---SEAIVSEY------MRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRH------LSDHLSELVENTLMDLENSKCIAIKDDID-VSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSL-RLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQ---IPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGH--------LISIKLLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCD 6438
            IRI+GLS +L N  DV  +L  + +   + F+   R  PL         T+   ++  M +  Y  +L ++     V+VFV     T   A  L   A    KN G A   +    +EY      +    N+ + E    G    H  +   +R+L+  LFS   +++LV + TL W +   A+ VI+  TQ+Y+ K   + D  A+D++Q+ GRA     D     +I+   +K       L +  P+ES     L D+ NAE          +AV +L++T+LY RM  NP  Y   G++H H      L     ++V +    L+ ++ I   +     S  + G  A+ +YI Y TIE F+    P+     +L ++C A EFE + +R  E   L ++      LP++    + +   K NILLQ Y+SR  +    L  DL+ I   + R++++  +     RW       + L++ I +  W     L+Q   +PH      LE+ EA   K   D +       +  M       Q + +  Q  P + L  E S        + V++ +  D      V+ +       E WW+ V +P   H        ++  ++LS   + V+          S +Y +  +SD +LG +
Sbjct:    9 IRIVGLSATLPNYLDVARFLHVNPYIGLFFFDSRFRPVPLSQTFIGVKTTNKMQQMHDMDEVCYDKVLEQVKAGHQVMVFVHARNATVRTAMALREMA----KNNGEAGFFTPPQSAEYGTAFKQVERSRNKPMRELFPDGFSTHHAGMLRPDRSLVEGLFSRGLVRVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGTFVDLGALDVMQIFGRAGRPQYDTFGLGIIITSHDKLGRYLTLLTQQNPIESQFQASLQDNLNAEDEAGLATAAFEAVRWLSYTYLYVRMRANPLAY---GINHSHYQADPSLHKFREQMVVDAGRKLDKARMIRFDERTGYFSPTDTGRTASHFYIKYNTIETFNDYFGPHLTESDVLSMVCKAEEFEQIKVREDELGELEQLADGYCLLPVAGG--VENGYGKVNILLQTYISRGDVDCFSLVSDLSYIAQNAARIVRSLFETALRKRWPTMTSRLLALSKAIDRRLWGWAHPLRQFSALPH----TTLEKLEAR--KMTVDKLRDMSSHDIGHMIHHVAMGQKIKQCVQQIPTLAL--EASIQPITRTVLRVRLSITADFTWCDQVHGSV-----GEPWWIWVEDPTNDHIYHSENFMILKKQVLSQEAQCVTFTIPIFEPLPS-QYYVRAVSDRWLGSE 647

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Sea Lamprey
Match: ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:NCBI gene;Acc:100332599])

HSP 1 Score: 933.71 bits (2412), Expect = 0.000e+0
Identity = 472/1143 (41.29%), Postives = 710/1143 (62.12%), Query Frame = 1

Query: 2005 MQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYA-GKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMG--TVRNIHESIDWLRYTYLYIRMRKNPSLYGVE-NVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLL--KEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF----GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNP 5388
            ++S+ S I  RIVGLSATLPN  D+A F+HV+ + GLF FDS +RPVP+ Q ++G+     ++++  M+++ Y+KV+E     HQV++FVH+R  TV TA A++E   N    G F   + A      + +++ +N  +++L P GF+ HHAG+   DR+ VE LF+   ++VLV T+TLAWGVNLPAH VIIKGTQ+Y   +G + +L ALDVMQ+FGRAGRPQYDT G+GI+IT+ ++L  YL+LL +Q PIESQ  + L DNLNAE   G  T   I E++ WL YTYLY+RMR NP  YG+  N L   P ++     ++  A   L+KA MI FD+R+G F   + GR A+++Y    T++    +    + + +V  +  K  EF  I VRE++  E+++L +    +P+  G E+   K+N LLQ YIS+  ++ F+L SD +YI+Q+AAR++R++FE  L K+W ++T  +L   K +++R+W  + PLRQF  +P    +KLE + +  D+L D   H++G ++++  MG+ I + + QIP L L+  +QPITR+ ++V L+IT DF WC + HGS  + +WI+VED  +++I H E F++  K+    +   + F + I++PLP  YY+RAVSD+W+G E    I F  ++LPE++ P TELLDLQ LP  AL +   E++Y  + + FN +QTQ F +LY+ D NV +GAPTGSGKTV AE+AI R+F+    A+ VY+  L  L + R  +W        G     V++LTG+   D ++I+ A +IV+T E WD +SR W  +  ++ + L ++D++HL+G    G  LEVI SRT ++SS  E P+R++GLS +L NARD+ +WL       +NF PSVR  PL+  I  F   H   R+A M+KP +Q I   SP  PV++FV + +QT   A  L+ +   +   K +    E  +   +  + +  L   L+ G+G  H  L   +R  + ELF +  IQ+L+ + TL W +   A+LVI+  T+ ++GK   Y D+   D++QM+GRA     DD  ++VI     KKDF +KFL+EP P+ES L   L DH NAEI + TI +KQDA+DY+TWT+ + R+  NP
Sbjct:    1 VESTQSMI--RIVGLSATLPNYLDVARFLHVNPYIGLFFFDSRFRPVPLSQTFIGVKTTNKMQQMHDMDEVCYDKVLEQVKAGHQVMVFVHARNATVRTAMALREMAKNNGEAGFFTPPQSAEYGTAFKQVERSRNKPMRELFPDGFSTHHAGMLRPDRSLVEGLFSRGLVRVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGTFVDLGALDVMQIFGRAGRPQYDTFGLGIIITSHDKLGRYLTLLTQQNPIESQFQASLQDNLNAEDEAGLATAAYIFEAVRWLSYTYLYVRMRANPLAYGINYNELWRSPNVEWFREQMVVDAGRKLDKARMIRFDERTGYFSPTDTGRTASHFYIKYNTIETFNDYFGPHLTESDVLSMVCKAEEFEQIKVREDELGELEQLADGYCLLPVAGGVENGYGKVNILLQTYISRGDVDCFSLVSDLSYIAQNAARIVRSLFETALRKRWPTMTSRLLALSKAIDRRLWGWAHPLRQFSALPHTTLEKLEARKMTVDKLRDMSSHDIGHMIHHVAMGQKIKQCVQQIPTLALEASIQPITRTVLRVRLSITADFTWCDQVHGSVGEPWWIWVEDPTNDHIYHSENFMILKKQVLSQEAQCVTFTIPIFEPLPSQYYVRAVSDRWLGSEAVCAINFQQLILPERHPPHTELLDLQPLPVSALGDARLEALY--RFTHFNPVQTQIFHTLYHGDGNVLLGAPTGSGKTVAAELAIFRIFNAHPGAKAVYIAPLKALVRERMEDWKVRLEPEAGCAAARVVELTGDVTPDARAIASADLIVTTPEKWDGVSRSWHSRSYVKQVALLVIDEIHLLGDD-RGPVLEVIVSRTNFISSHTEKPVRVVGLSTALANARDLADWLAIKQVILFNFRPSVRPVPLEAHIHGFPGQHYCPRMATMNKPTFQAIRTHSPAKPVLIFVSSRRQTRLTALDLIAFLAGEDNPKQWLHTDETEMEHIISTVKDSNLKLCLAFGIGMHHAGLHERDRRTVEELFVNTRIQVLIATSTLAWGVNFPAHLVIIKGTEYFDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVIFVHDLKKDFYKKFLYEPFPVESSLLEVLADHLNAEITSGTITSKQDAMDYITWTYFFRRLIMNP 1138

HSP 2 Score: 300.827 bits (769), Expect = 5.684e-84
Identity = 182/466 (39.06%), Postives = 263/466 (56.44%), Query Frame = 1

Query: 1510 AFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKS----YNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNP 2895
            A  +    N +Q++++ T    D N+LL APTG+GKT  A L + R    H            K VYIAP+K+LV E    +  RL+        +V  L+GD       I    +IV TPEKWD +SR    ++Y + V LL+IDEIHLL D+RGPVLE IV+RT     SSH+   +R+VGLS  L N  D+A+++ + K   LF F  S RPVP+E    G   +    R+  MN   ++ +  ++    VLIFV SR++T  TA  +       D    +L   +     ++  +  VK+ +LK  L +G  +HHAGL   DR  VEELF +  IQVL++TSTLAWGVN PAH+VIIKGT+ +      + +    DV+QM GRAGRPQ+D +G  ++  ++ +  +Y   L E  P+ES L+  LAD+LNAEI  GT+ +  +++D++ +TY + R+  NP
Sbjct:  688 ALYRFTHFNPVQTQIFHTLYHGDGNVLLGAPTGSGKTVAAELAIFRIFNAHPGA---------KAVYIAPLKALVRERMEDWKVRLEPEAGCAAARVVELTGDVTPDARAIASADLIVTTPEKWDGVSRSWHSRSYVKQVALLVIDEIHLLGDDRGPVLEVIVSRT--NFISSHTEKPVRVVGLSTALANARDLADWLAI-KQVILFNFRPSVRPVPLEAHIHGFPGQHYCPRMATMNKPTFQAIRTHSPAKPVLIFVSSRRQTRLTALDLIAFLAGEDNPKQWLHTDETE---MEHIISTVKDSNLKLCLAFGIGMHHAGLHERDRRTVEELFVNTRIQVLIATSTLAWGVNFPAHLVIIKGTEYFDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVIFVHDLKKDFYKKFLYEPFPVESSLLEVLADHLNAEITSGTITSKQDAMDYITWTYFFRRLIMNP 1138

HSP 3 Score: 155.606 bits (392), Expect = 4.328e-38
Identity = 168/664 (25.30%), Postives = 284/664 (42.77%), Query Frame = 1

Query: 4546 IRIIGLSYSLTNARDVGEWLDCH-HTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTIL-KLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRA---SEAIVSEY------MRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAE--IVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHL--SDHLSELVENTLMD----LENSKCIAIKDDID-VSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSL-RLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQ---IPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGH--------LISIKLLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCD 6438
            IRI+GLS +L N  DV  +L  + +   + F+   R  PL         T+   ++  M +  Y  +L ++     V+VFV     T   A  L   A    KN G A   +    +EY      +    N+ + E    G    H  +   +R+L+  LFS   +++LV + TL W +   A+ VI+  TQ+Y+ K   + D  A+D++Q+ GRA     D     +I+   +K       L +  P+ES     L D+ NAE      T     +AV +L++T+LY RM  NP  Y   G+++  L  S ++    E  ++D    L+ ++ I   +     S  + G  A+ +YI Y TIE F+    P+     +L ++C A EFE + +R  E   L ++      LP++    + +   K NILLQ Y+SR  +    L  DL+ I   + R++++  +     RW       + L++ I +  W     L+Q   +PH      LE+ EA   K   D +       +  M       Q + +  Q  P + L  E S        + V++ +  D      V+ +       E WW+ V +P   H        ++  ++LS   + V+          S +Y +  +SD +LG +
Sbjct:    8 IRIVGLSATLPNYLDVARFLHVNPYIGLFFFDSRFRPVPLSQTFIGVKTTNKMQQMHDMDEVCYDKVLEQVKAGHQVMVFVHARNATVRTAMALREMA----KNNGEAGFFTPPQSAEYGTAFKQVERSRNKPMRELFPDGFSTHHAGMLRPDRSLVEGLFSRGLVRVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGTFVDLGALDVMQIFGRAGRPQYDTFGLGIIITSHDKLGRYLTLLTQQNPIESQFQASLQDNLNAEDEAGLATAAYIFEAVRWLSYTYLYVRMRANPLAY---GINYNELWRSPNVEWFREQMVVDAGRKLDKARMIRFDERTGYFSPTDTGRTASHFYIKYNTIETFNDYFGPHLTESDVLSMVCKAEEFEQIKVREDELGELEQLADGYCLLPVAGG--VENGYGKVNILLQTYISRGDVDCFSLVSDLSYIAQNAARIVRSLFETALRKRWPTMTSRLLALSKAIDRRLWGWAHPLRQFSALPH----TTLEKLEAR--KMTVDKLRDMSSHDIGHMIHHVAMGQKIKQCVQQIPTLAL--EASIQPITRTVLRVRLSITADFTWCDQVHGSV-----GEPWWIWVEDPTNDHIYHSENFMILKKQVLSQEAQCVTFTIPIFEPLPS-QYYVRAVSDRWLGSE 648

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005265.1 (pep scaffold:Pmarinus_7.0:GL487662:5509:13814:-1 gene:ENSPMAG00000004793.1 transcript:ENSPMAT00000005265.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 383.259 bits (983), Expect = 4.123e-120
Identity = 191/355 (53.80%), Postives = 263/355 (74.08%), Query Frame = 1

Query: 5413 SHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPIS-EDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVS--KSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            SHRHLSDHLSELVE+TL DLE+SKCI+++D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +K+R L++++ NA+E+  +P+RH EDV+L R + + ++P    + + +DP  KAN+LLQA+LSR+ +  AEL+ D   IL +++RLIQACVDVLSSN WL PALAAMELAQM TQA W +DS LKQ+PHF     ++RC   GV++VFD++E+ED  + AL+   D K+ DVARF   YPNI+L+YE+S   +V +G  V V + L R+++    V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP   G++ YTLYFMSD+Y+GCDQEY+F++ V
Sbjct:    1 SHRHLSDHLSELVESTLGDLEHSKCISLEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKIRGLIDIVSNASEYAAIPIRHHEDVLL-RQQLAQKVPNKLTNPKFNDPHAKANLLLQAHLSRMQLN-AELQSDTEDILTQAIRLIQACVDVLSSNGWLSPALAAMELAQMCTQAMWSKDSYLKQLPHFTADH-VKRCTEQGVESVFDVLEMEDAARSALLQLDDSKMADVARFCNRYPNIELSYELSDKDNVHSGSAVVVMVQLEREDEVTGPVIAPFFPQKREEGWWVVIGDPKTNSLISIKRLTLQQKAKVKLDFVAP-APGTHHYTLYFMSDAYMGCDQEYRFSVEV 351

HSP 2 Score: 67.781 bits (164), Expect = 1.041e-11
Identity = 78/349 (22.35%), Postives = 149/349 (42.69%), Query Frame = 1

Query: 2938 LDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXX-XXNVPVPIKEGA-EDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIP--FD--RLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS----------SQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETE 3936
            L +H   L+ +    LE ++ I+ +        N +G IAAYYY    T+++    L        +  + S  +E+  I +R  + + +++   + VP  +      DP  K N LLQA++S+++L    L SDT  I   A RL++A  +V  S  W S  L+ +E  +   Q MW+    L+Q      +  K+  ++ +   FD   + D     L +L ++ KM   + ++ ++ P + L   L           + +    E   +  G            +G+W+ + D  + +++  +   L++K K     +K       P    Y +  +SD ++G + E
Sbjct:    5 LSDHLSELVESTLGDLEHSKCISLEDEMDVAPLN-LGMIAAYYYINYTTIELFSMSLNAKTKIRGLIDIVSNASEYAAIPIRHHEDVLLRQQLAQKVPNKLTNPKFNDPHAKANLLLQAHLSRMQLNA-ELQSDTEDILTQAIRLIQACVDVLSSNGWLSPALAAMELAQMCTQAMWSKDSYLKQLPHFTADHVKRCTEQGVESVFDVLEMEDAARSALLQL-DDSKMAD-VARFCNRYPNIELSYELSDKDNVHSGSAVVVMVQLEREDEVTGPVIAPFFPQKREEGWWVVIGDPKTNSLISIKRLTLQQKAK-----VKLDFVAPAPGTHHYTLYFMSDAYMGCDQE 344

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003190.1 (pep scaffold:Pmarinus_7.0:GL480029:355:29241:-1 gene:ENSPMAG00000002910.1 transcript:ENSPMAT00000003190.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 193.356 bits (490), Expect = 1.257e-51
Identity = 162/589 (27.50%), Postives = 282/589 (47.88%), Query Frame = 1

Query: 1960 RGPVLEAIVARTMR-------AMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLF-KFDSSYRPVPMEQEYLGI---NERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRP-QYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXX----XXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLES---CKEVEQRMWACSCPLRQ--FKKVPWEITKKLEKKNI-PFDRLIDQKHHELGELVNNH-KMGKTIYKYIHQIPKLNLKI 3657
            RG  LEA+V+R          A+Q  H+   +RI+ ++AT+PN EDIAE++       +F K D  +RP  + +  LG    + + A K   ++N  +   +  Y+ +   LIF  +R+     A  + +          F+ D +      ++    +K+  L+DLL  G A HHAG+A +DR  +E++F    ++VL STSTLA GVNLPAH+VI+K T  Y    G   E    + +QM GRAGRP Q+D     +++T +     Y  +L+    +ES L   L ++LNAEIV+ T+ +++ ++DW+R T+LYIR  KNP  Y     L  +         L   + + L   ++     ++G+    ++GR+ A YY   +T+ +    L+ S    ++  + + C E++ I +R  +K  +          +  P+    +    K+NCL+Q  +  + L+ F L  D A I ++  RL + + E    K   +   +VL +    K    ++W  S   +Q     V + ++  L    +  F+++          +VN H   G  I + +  +PK  +++
Sbjct:   10 RGATLEAVVSRMKTLIFLPRDALQPLHTCRGVRIIAVAATIPNIEDIAEWLSDRDGTAIFIKLDGKHRP-KLRKIVLGFPFYSVQTAFKFYLILNYKLARVIQTYSEQKPTLIFCATRRSVQQAAATLAK-------YAKFMIDFQHRQSHCRKHASHLKDIKLRDLLMKGIAYHHAGMAASDRRNIEDVFLQGELRVLFSTSTLAIGVNLPAHLVIVKSTMRY-TRGGMLQEYG--ETLQMIGRAGRPQQFDVSATAVILTRKK----YERMLSGTQELESSLHINLTEHLNAEIVLHTITDVNVALDWIRSTFLYIRALKNPKHYKFPAGLSKEDIEKKLLSELCLESLNSLATFKLNCM--QNGDIKPTDVGRLMASYYIAFDTIKLFGT-LQGSEAMQDLVNLVAHCREYKYIALRVNEKKTLNTFNMAKNHTIRFPMPGKIKTIEMKVNCLIQPQLGCV-LQDFALIQDIAKIFRTGIRLTKCLAEFLQQKDKQNNFQAVLNAVHLAKCFRAKLWKNSPVFKQQNVSAVSFSLSSALVNAGLTSFEKIYTVNAIGPVVIVNRHPPFGNQIKEAVQHLPKYQVRV 579

HSP 2 Score: 125.946 bits (315), Expect = 1.543e-29
Identity = 121/533 (22.70%), Postives = 232/533 (43.53%), Query Frame = 1

Query: 4456 LHLIGSQHNGTTLEVICSRTR---YMSSQLETP------IRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRP----LDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYA-----LSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNL-KGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRI----KQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSS---NRWLGPALAAMELAQMITQAQWHRDSLLKQ 5976
            +H +  +  G TLE + SR +   ++      P      +RII ++ ++ N  D+ EWL              +HRP    + +    +++         ++  + + I   S   P ++F  T +  ++ A  L  YA        +++  R      + ++++I    L + L  G+ + H  ++ ++R  + ++F    +++L  + TL   +   A+LVIV  T  Y  +  M  +Y   + +QM+GRA      D  +  +  T KK   ++ L     LES L   L +H NAEIV  TI +   A+D++  TFLY R  +NP +Y    G+S   +   L   +    ++   +  +    + D+   ++G +   YYI + TI++F  +L+ +  ++ L+ L+ +  E++ + LR  E   L         ++R P+    ++     K N L+Q  L  V ++   L +D+ +I    +RL +   + L            L A+ LA+      W    + KQ
Sbjct:    2 VHTVEDESRGATLEAVVSRMKTLIFLPRDALQPLHTCRGVRIIAVAATIPNIEDIAEWLSDRDGTAIFIKLDGKHRPKLRKIVLGFPFYSVQTAFKFYLILNYKLARVIQTYSEQKPTLIFCATRRSVQQAAATLAKYAKFMIDFQHRQSHCRKH----ASHLKDIK---LRDLLMKGIAYHHAGMAASDRRNIEDVFLQGELRVLFSTSTLAIGVNLPAHLVIVKSTMRYT-RGGMLQEYG--ETLQMIGRAGRPQQFDVSATAVILTRKK--YERMLSGTQELESSLHINLTEHLNAEIVLHTITDVNVALDWIRSTFLYIRALKNPKHYKFPAGLSKEDIEKKLLSELCLESLNSLATFKLNCMQNGDIKPTDVGRLMASYYIAFDTIKLFG-TLQGSEAMQDLVNLVAHCREYKYIALRVNEKKTLNTFNMAKNHTIRFPMPG--KIKTIEMKVNCLIQPQLGCV-LQDFALIQDIAKIFRTGIRLTKCLAEFLQQKDKQNNFQAVLNAVHLAKCFRAKLWKNSPVFKQ 518

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Sea Lamprey
Match: helq (helicase, POLQ like [Source:ZFIN;Acc:ZDB-GENE-060503-421])

HSP 1 Score: 103.219 bits (256), Expect = 3.115e-22
Identity = 108/407 (26.54%), Postives = 183/407 (44.96%), Query Frame = 1

Query: 1564 ALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHL--SREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXX--XXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYL-------GINERKAVKR-----IELMN-----DLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENE 2721
            ++   +N++   PT  GKT VA + M+RE+          R+D   I+   P  ++V E   S S       + +   +G       R++  +  + + T EK   +     E+   Q + L+++    +      RG  LE  +A+        +++   +I+G+SATL N  D+ +F++ +       + + +RPV + +EY+       G+N +          I L++     D +   V E    H  L+F  ++K   N A+ I  K L +    L  R+++   L+ +   D      L+  +PYG A HH+GL   +R  +EE ++   + +L  TSTLA GVNLPA  VI++      P  G  + LS     QM GRAGR   D+ G  I I N  +
Sbjct:   33 SVRQGKNLIYSLPTSGGKTLVAEILMLRELL-------CKRRDALLIL---PYVAIVQEKVRSLSVFGVELEIFIEEYAGSKGRMPPRKKRKKNSLYIATIEKAHSLVNSLLEEGRMQEIGLIVVDELHMLGEGGSRGATLEQTLAKV------QYTSKTTQIIGMSATLSNINDLQKFLNAEL------YTNDFRPVEL-REYIKLGDSIYGVNNKALCPEEQFDFIRLLSYKMDPDHIVALVTEVIPAHSCLVFCPTKKNCENVAEMIC-KYLAKTRHTLHHREEEKRALLAELQADGELCPVLRRTVPYGLAYHHSGLTGEERRLIEEAYSAGTLCLLTCTSTLAAGVNLPARRVILRS-----PYIGN-SFLSRSQYKQMVGRAGRAGIDSSGESITIVNSRD 409

HSP 2 Score: 83.5741 bits (205), Expect = 3.092e-16
Identity = 91/382 (23.82%), Postives = 162/382 (42.41%), Query Frame = 1

Query: 4120 DENVFIGAPTGSGKTVCAEIAIMR-LFSNRQDARCV--YVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMD---NKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIG-SQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNA---------TRLAAMSKP---VYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASE---AIVSEYMRNIS-NEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVI 5196
             +N+    PT  GKT+ AEI ++R L   R+DA  +  YV  + +         +  FG   +  I+    +       K   K  + ++T E    L     ++  +Q I L +VD+LH++G     G TLE   ++ +Y S       +IIG+S +L+N  D+ ++L+     T +F P      + +    + + + A          RL +       +   + ++ P    +VF PT K  E +A ++  Y    +       E   A+++E   +     +L  T+  G+ + H  L+  ER L+ E +S+ ++ +L  + TL   +   A  VI+    + N         S     QMVGRA  A +D +   I
Sbjct:   37 GKNLIYSLPTSGGKTLVAEILMLRELLCKRRDALLILPYVAIVQE-----KVRSLSVFGVELEIFIEEYAGSKGRMPPRKKRKKNSLYIATIEKAHSLVNSLLEEGRMQEIGLIVVDELHMLGEGGSRGATLEQTLAKVQYTSK----TTQIIGMSATLSNINDLQKFLNA-ELYTNDFRPVELREYIKLGDSIYGVNNKALCPEEQFDFIRLLSYKMDPDHIVALVTEVIPAHSCLVFCPTKKNCENVAEMICKYLAKTRHTLHHREEEKRALLAELQADGELCPVLRRTVPYGLAYHHSGLTGEERRLIEEAYSAGTLCLLTCTSTLAAGVNLPARRVILRSPYIGN------SFLSRSQYKQMVGRAGRAGIDSSGESI 402

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Yeast
Match: BRR2 (RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD [Source:SGD;Acc:S000000974])

HSP 1 Score: 1255.35 bits (3247), Expect = 0.000e+0
Identity = 734/1916 (38.31%), Postives = 1127/1916 (58.82%), Query Frame = 1

Query:  847 ANSEKLNVNDIDAFWLQRTLSKH--FTDPNECQKRTKDIL-EVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSN-----VISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKT--LNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGT-IRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGK-HQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPF-DRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSI----YDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQD-ARCVYVTALNDLAQLRYTEWMKTFGAL--GKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTF-NITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDID-----------------VSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARD-EDNISSVYANNFPYKREESWWLVVGEPNQGHLISIK--LLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            +N E + +  ID F+LQR L     + D +  Q  ++ IL ++  +  N   LE KL+ ++  +   L   + +N+  I++  +L  S   E  N IE          +++A   N     D+V   + R+T     ++ +  +   S+       SN     ++DL+ I F + S LMT     LP+GSF++ KP Y+ + +PAP  KP+  D  L +I  LP + + AF   +T  LN IQSKV+  A E D N+L+CAPTG+GKTN+ALLT+++ +  H N     +    FKIVYIAP+K+LV E    F  RL    +KVA L+GDS LSR++I+ETQ++V TPEKWDI +R S+     +LV+LLIIDEIHLLHD+RGPVLE+IVART  A  S +     RI+GLSATLPN ED+  F+ V K  GLF FDSS+RP P+ Q++ GI ER ++K+++ MND  YEKV+E   + +Q+++FVHSRKET  TA  +K K    +      ++   S  +L+ +   V +  L+ L+  G   HHAGL  +DR+  E+LF D  +QVLV T+TLAWGVNLPAH VIIKGT VY P+KG W +LS  DV+QM GRAGRP+YDT G GI+IT+++ + YYLS+LN+QLPIESQ +SKL DNLNAE+V G ++  +++++WL YTYLY+RM  +P LY V ++   D  L     +L+++A  IL++ E++ +D  +    + ++G IA+ +Y  + +MDV  + L +    I++F++FS   EF+ ++VR E+K E+K+LLE  P+PI+E  +DP  K+N LLQ+Y SQLK E F L+SD  +I Q+A RL+RAMFE+ L + W   T  +L  CK    +MW  +CPLRQFK  P E+ K+LE   +P+ D L  +   E+G  + + K GK +Y  + + PK+++  + QPITRS M+  + I  D+ W    HGS + F + +ED   ++IL+Y+   +       +  L F   +     + LPP +++  +S+ W   E EI + F    LP+K  P T LL+   +    L N+++  ++  K   FN IQ+Q FESLYNS+++VF+G+  G+GKT  AE+A++  +  RQ+  R VY+    +      ++W K F  L  GK + KL  + +++ K ++K+H++++T   +++LSRRW+++K IQ+++L I DD H I     G   E + SR  ++++QLE  IR + LS  L NARD GEW     +  YNF+PS R  PL+I IQ+F ++ H +   + +      +       +   VF+P+ K   E+A   M ++ + + +     E  +  Y+  +++  L   L  GVG +++ ++ N+  ++  L+   ++ +L++S   C +       VI++ T +Y+G +  Y  Y+  +L++MVG A+       + +I+   N K + +KFL EPLP ES+L + +HD  N EI    I++KQD VD+ T+++ Y R+  NP+YY ++  S   +S  LS LVE  L DL  S  I I DD +                 +S ++ G+IA+ Y + + TI+ F  SL   S ++ +L ++  A EFE +PLR G+  +L ++ + L L   E         K  +LLQAY SR+ +   + + DL  IL K V LI   VD+LS+N +L  A  AM+LAQM+ Q  W  D+ L+QIPHFN  K+LE+C+   V+TV+D+M LEDE++  ++   D +L  VA F   YPN++LTY +  S S+ +G +  + I L RD E     V +  +P+ + ESWWLV+GE ++  L +IK   L+  T++  L FD P  SG +  T++ + DSYL  D+E  F INV
Sbjct:  278 SNIESVPIYSIDEFFLQRKLRSELGYKDTSVIQDLSEKILNDIETLEHNPVALEQKLVDLLKFENISLAEFILKNRSTIFWGIRLAKSTENEIPNLIE----------KMVAKGLN-----DLVEQYKFRETTHSKRELDSGDDQPQSSEAKRTKFSNPAIPPVIDLEKIKFDESSKLMTVTKVSLPEGSFKRVKPQYDEIHIPAPS-KPV-IDYELKEITSLPDWCQEAFPSSETTSLNPIQSKVFHAAFEGDSNMLICAPTGSGKTNIALLTVLKALSHHYNPKTKKLNLSAFKIVYIAPLKALVQEQVREFQRRLAFLGIKVAELTGDSRLSRKQIDETQVLVSTPEKWDITTRNSNNLAIVELVRLLIIDEIHLLHDDRGPVLESIVARTFWA--SKYGQEYPRIIGLSATLPNYEDVGRFLRVPKE-GLFYFDSSFRPCPLSQQFCGIKERNSLKKLKAMNDACYEKVLESINEGNQIIVFVHSRKETSRTATWLKNKFAEENITHKLTKNDAGSKQILKTEAANVLDPSLRKLIESGIGTHHAGLTRSDRSLSEDLFADGLLQVLVCTATLAWGVNLPAHTVIIKGTDVYSPEKGSWEQLSPQDVLQMLGRAGRPRYDTFGEGIIITDQSNVQYYLSVLNQQLPIESQFVSKLVDNLNAEVVAGNIKCRNDAVNWLAYTYLYVRMLASPMLYKVPDI-SSDGQLKKFRESLVHSALCILKEQELVLYDAENDVIEATDLGNIASSFYINHASMDVYNRELDEHTTQIDLFRIFSMSEEFKYVSVRYEEKRELKQLLEKAPIPIREDIDDPLAKVNVLLQSYFSQLKFEGFALNSDIVFIHQNAGRLLRAMFEICLKRGWGHPTRMLLNLCKSATTKMWPTNCPLRQFKTCPVEVIKRLEASTVPWGDYLQLETPAEVGRAIRSEKYGKQVYDLLKRFPKMSVTCNAQPITRSVMRFNIEIIADWIWDMNVHGSLEPFLLMLEDTDGDSILYYDVLFITPDIVGHEFTLSFTYELKQHNQNNLPPNFFLTLISENWWHSEFEIPVSFNGFKLPKKFPPPTPLLENISISTSELGNDDFSEVFEFKT--FNKIQSQVFESLYNSNDSVFVGSGKGTGKTAMAELALLNHW--RQNKGRAVYINPSGEKIDFLLSDWNKRFSHLAGGKIINKLGNDPSLNLKLLAKSHVLLATPVQFELLSRRWRQRKNIQSLELMIYDDAHEISQGVYGAVYETLISRMIFIATQLEKKIRFVCLSNCLANARDFGEWAGMTKSNIYNFSPSERIEPLEINIQSFKDVEHISFNFSMLQMAFEASAAAAGNRNSSSVFLPSRKDCMEVASAFMKFSKAIEWDMLNVEEEQIVPYIEKLTDGHLRAPLKHGVGILYKGMASNDERIVKRLYEYGAVSVLLISKD-CSAFACKTDEVIILGTNLYDGAEHKYMPYTINELLEMVGLASGNDSMAGKVLILTSHNMKAYYKKFLIEPLPTESYLQYIIHDTLNNEIANSIIQSKQDCVDWFTYSYFYRRIHVNPSYYGVRDTSPHGISVFLSNLVETCLNDLVESSFIEI-DDTEAEVTAEVNGGDDEATEIISTLSNGLIASHYGVSFFTIQSFVSSLSNTSTLKNMLYVLSTAVEFESVPLRKGDRALLVKLSKRLPLRFPEHTSSGSVSFKVFLLLQAYFSRLEL-PVDFQNDLKDILEKVVPLINVVVDILSANGYLN-ATTAMDLAQMLIQGVWDVDNPLRQIPHFNN-KILEKCKEINVETVYDIMALEDEERDEILTLTDSQLAQVAAFVNNYPNVELTYSLNNSDSLISGVKQKITIQLTRDVEPENLQVTSEKYPFDKLESWWLVLGEVSKKELYAIKKVTLNKETQQYELEFDTP-TSGKHNLTIWCVCDSYLDADKELSFEINV 2162

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Yeast
Match: SLH1 (Putative RNA helicase related to Ski2p; involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses [Source:SGD;Acc:S000003503])

HSP 1 Score: 1061.98 bits (2745), Expect = 0.000e+0
Identity = 657/1828 (35.94%), Postives = 1049/1828 (57.39%), Query Frame = 1

Query:  988 QELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERN--KIEAEMKTDPKSNRILADLRN--IDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNY--GSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADEN-----LVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGT----IRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRI-ELMNDLVYEKVMEYAGK-HQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFL-----RDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDT-KGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVE-NVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXX-XNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGAL-GKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTF--NITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLM---GYALSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLK-GVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISE------DRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPH----------FNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDD------KLQDVARFF----QCYPNID-LTYEVSKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLV 6288
            QELE +LL  +G    DLV +L +++ MI          TP E     I+  + + P+      D+RN  +   ED     +NRK    +  I+        +V   Y  GS   +      FT            LP G+ R +   +  + +PA       +++N     L+KI+DL  + K  F   +TLN+IQS VY  A +++EN+L+CAPTGAGKT++ALLT++  I +    +G     I+ DDFK++Y+AP+K+L  E+ + FS++L  +N++V  L+GD  L++ EI  TQ+IV TPEKWD+++RK+  +      VKLLIIDE+HLLH++RG V+E +VART+R ++SS S I  RI+GLSATLPN  D+A+F+ V++  G+F FD S+RP P+EQ+ LG   +   ++  E ++ + Y+K+ E   + +QV++FVHSRKETV +A+   +   +   + LF      +DK + +LV      K ++ D+K++  +GF +HHAG+A +DRN  E++F D  I+VL  T+TLAWGVNLPA  VIIKGTQVY   KG + +L   DV+Q+FGR GRP + +  G GI+ T+ + L +Y+SL+ +Q PIES+  SKL DNLNAEI +G+V N+ E+I+WL YTY+++RMRKNP  YG++   + +DP L    R +I  AA  L   +MI FD+ S  FI+ ++GR+++ +Y  NE++++  +       + +V  + S  +EF  I  REE+  E+K+L  E+V   I    + P  K N LLQAYISQ ++    LSSD+ Y++Q++ R+ RA+F + ++++W   +  +L  CK +E+R+WA   PL QF  +P  I +++       + L++ +  ELGELV+N K G  +YK + + PK+N++  + PIT + M++ + + PDF W  + HG +Q FW+FVE+     ILH+E F+L  +  N+ H + F + + DPLPP   ++ VSD WIG E+   I F +++ P      T+LL L+ LP  AL+N   ESIY  K  +FN +QT  F +LYN++EN F+G+PTGSGKT+ AE+AI   F      + VY+  +  L + R  +W K    + G  V++LTG++  D K +  A I+++T E +D +SR W+ +K +Q++ L I+D++HL+ S   G  LE+I SR  Y+SSQ + P+R++G+S +++NA D+  WL       YNF  SVR  PL + I  F  N+      +  M+KPV+  I + SP+ P ++FV + +QT   A  L+   G   + ++      E  +  Y+  ++++ L  +L  G+G  H  L   +R++  +LF    IQIL+ + TL W +   A+LVI+  TQ ++ K   Y D    D++QM+GRA   + D    +++  + +KK F + FL+   P+ES L   L DH  AEI + +I NKQ+A+D+L+WTFL+ R   NP YY ++   S   +S+HLS L+++TL +L  S+C+ +  D D+ A     I+++YYI + TI      +  ++  + +L  +  A E+ +LP+R GE ++   + Q  R  +        +  + DP  K  +LLQA+LSRV +  A+  +D   +L +S+R++QA +DV S   +    L  +++ Q I Q  W+ D  +  +P           F+E   +E       K +  L E+       L+N  D       + +D  + F    Q  P ++ + +E  ++       S   HL+   +N   VY + FP  ++E W+L+
Sbjct:  131 QELEKELLDFLGTGNIDLVSLLLQHRRMIV--------ATPIETTILLIKNAVNSTPEF-LTQQDIRNQVLKSAED----AKNRKLNPATKIIKY------PHVFRKYEAGSTTAMAFAGQKFT------------LPVGTTRMSYNTHEEIIIPAADQA---SNKNYLYTKLLKISDLDHFCKTVF-PYETLNQIQSLVYPVAYKTNENMLICAPTGAGKTDIALLTIINTIKQFSVVNGENEIDIQYDDFKVIYVAPLKALAAEIVDKFSKKLAPFNIQVRELTGDMQLTKAEILATQVIVTTPEKWDVVTRKANGDNDLVSKVKLLIIDEVHLLHEDRGSVIETLVARTLRQVESSQSMI--RIIGLSATLPNFMDVADFLGVNRQIGMFYFDQSFRPKPLEQQLLGCRGKAGSRQSKENIDKVAYDKLSEMIQRGYQVMVFVHSRKETVKSARNFIKLAESNHEVDLFAPDPIEKDKYSRSLV------KNRDKDMKEIFQFGFGIHHAGMARSDRNLTEKMFKDGAIKVLCCTATLAWGVNLPADCVIIKGTQVYDSKKGGFIDLGISDVIQIFGRGGRPGFGSANGTGILCTSNDRLDHYVSLITQQHPIESRFGSKLVDNLNAEISLGSVTNVDEAIEWLGYTYMFVRMRKNPFTYGIDWEEIANDPQLYERRRKMIVVAARRLHALQMIVFDEVSMHFIAKDLGRVSSDFYLLNESVEIFNQMCDPRATEADVLSMISMSSEFDGIKFREEESKELKRLSDESVECQIGSQLDTPQGKANVLLQAYISQTRIFDSALSSDSNYVAQNSVRICRALFLIGVNRRWGKFSNVMLNICKSIEKRLWAFDHPLCQFD-LPENIIRRIRDTKPSMEHLLELEADELGELVHNKKAGSRLYKILSRFPKINIEAEIFPITTNVMRIHIALGPDFVWDSRIHGDAQFFWVFVEESDKSQILHFEKFILNRRQLNNQHEMDFMIPLSDPLPPQVVVKVVSDTWIGCESTHAISFQHLIRPFNETLQTKLLKLRPLPTSALQNPLIESIYPFK--YFNPMQTMTFYTLYNTNENAFVGSPTGSGKTIVAELAIWHAFKTFPGKKIVYIAPMKALVRERVDDWRKKITPVTGDKVVELTGDSLPDPKDVHDATIVITTPEKFDGISRNWQTRKFVQDVSLIIMDEIHLLASDR-GPILEMIVSRMNYISSQTKQPVRLLGMSTAVSNAYDMAGWLGVKDHGLYNFPSSVRPVPLKMYIDGFPDNLAF-CPLMKTMNKPVFMAIKQHSPDKPALIFVASRRQTRLTALDLIHLCGMEDNPRRFLNIDDEEELQYYLSQVTDDTLKLSLQFGIGLHHAGLVQKDRSISHQLFQKNKIQILIATSTLAWGVNLPAHLVIIKGTQFFDAKIEGYRDMDLTDILQMMGRAGRPAYDTTGTAIVYTKESKKMFYKHFLNVGFPVESSLHKVLDDHLGAEITSGSITNKQEALDFLSWTFLFRRAHHNPTYYGIEDDTSTAGVSEHLSSLIDSTLENLRESQCVLLHGD-DIVATPFLSISSYYYISHLTIRQLLKQIHDHATFQEVLRWLSLAVEYNELPVRGGEIIMNEEMSQQSRYSVESTFTDEFELPMWDPHVKTFLLLQAHLSRVDLPIADYIQDTVSVLDQSLRILQAYIDVASELGYFHTVLTMIKMMQCIKQGYWYEDDPVSVLPGLQLRRIKDYTFSEQGFIEMTPQQKKKKLLTLEEIGRFGYKKLLNVFDQLTFGMTESEDTKKRFVSVCQRLPVLEGMKFEEQENNEVLTFYSK--HLSSKHNNGFEVYCDKFPKIQKELWFLI 1907

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Yeast
Match: HFM1 (Meiosis specific DNA helicase; involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity [Source:SGD;Acc:S000003220])

HSP 1 Score: 272.322 bits (695), Expect = 9.557e-75
Identity = 206/599 (34.39%), Postives = 326/599 (54.42%), Query Frame = 1

Query: 1435 APKPKPL---EADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGD-SHLSREEINETQIIVCTPEKWDIISRKSSEKTYT-QLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKH--RGLFKFDSSYRPVPMEQEYLG--INERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVL-----IDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFL--KKSMGDIEVFKVFSKCAEFRNITVR 3183
            A KPK +   ++ +  +    LP   +  F K    N++QS+ + +  ES+EN ++ +PTG+GKT +  L ++R I K  N+D     ++ KI+YIAP KSL  EM  ++       NL V ML+ D S L  E+  +  II+ TPEKWD+++R+ S+ +   +LVKL+++DEIH + ++RG  LE I+ R     Q      ++R V LSAT+PN ED+A ++  +      +  FD SYR V + +   G   N +   ++  + N  + E + ++A    VLIF  +R  T++TAK +    LN     +F + KK          DK+    L + +  G A HHAG++  DR  VE+ F    I +L STSTLA GVNLPA++VIIKGT+ +  +  E  E S LDV+QM GRAGRPQ++T G  +++T+      Y +L++    +ES L   L ++L AE  + TV +I  +++WLR T+ Y+R  KNP+ Y   N       ++D  ++  C+ L+ T    L K ++I  D  +GE+ S   G     +Y + E+M   K+F+  KK +    +  + +   EF  + VR
Sbjct:  105 AKKPKKVTIRKSAKKCLSTTILPDSFRGVF-KFTEFNKMQSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLI-KETNSD----TNNTKIIYIAPTKSLCYEMYKNWFPSF--VNLSVGMLTSDTSFLETEKAKKCNIIITTPEKWDLLTRRWSDYSRLFELVKLVLVDEIHTIKEKRGASLEVILTRMNTMCQ------NIRFVALSATVPNIEDLALWLKTNNELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFCPTRASTISTAKFL----LNNH---IFSKSKKRCN---HNPSDKI----LNECMQQGIAFHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSW--NSSEIQEYSDLDVLQMIGRAGRPQFETHGCAVIMTDSKMKQTYENLIHGTDVLESSLHLNLIEHLAAETSLETVYSIETAVNWLRNTFFYVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDT----LVKVKII--DISNGEYKSTAYGNAMTRHYISFESM---KQFINAKKFLSLQGILNLLATSEEFSVMRVR 664

HSP 2 Score: 227.254 bits (578), Expect = 2.007e-60
Identity = 183/636 (28.77%), Postives = 310/636 (48.74%), Query Frame = 1

Query: 4063 KMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLF----SNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTN-MDNKSISKAHIIVSTAENWDVLSRRWKK-KKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYN---FNPSVRHRPLD--IEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIA-FLLMGYALSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNL--KGVSHRHLSD-HLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQS--LRLPISEDRRLSD----PRTKANILLQAYLSRVPIKAAELKEDLNQILIKS--------VRLIQACVDVL 5880
            K + FN +Q++ F S+Y S+EN  I +PTGSGKTV  E+AI+RL     S+  + + +Y+     L    Y  W  +F  L  +V  LT +T+ ++ +   K +II++T E WD+L+RRW    +  + ++L +VD++H I  +  G +LEVI +R   M       IR + LS ++ N  D+  WL  ++    N   F+ S R   L   +   +FN  ++  + A  +  + + I K + N PV++F PT   T   A FLL  +  S  K               N S++IL E +  G+ F H  +S+ +R  + + F + SI IL  + TL   +   AYLVI+  T+ +N  +    +YS +D++QM+GRA     +    +VIM  +  K   +  +H    LES L   L +H  AE   +T+ + + AV++L  TF Y R  +NP  Y    + VS   + D  +++  +  L  L   K I I +  +  +   G   T +YI + +++ F ++ K    ++ +L L+  + EF  + +RH E  +   I  S  L+ P   +++ S        K ++L+Q  L  +   + E    L+Q L++          RL++  VD  
Sbjct:  135 KFTEFNKMQSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCYEMYKNWFPSFVNL--SVGMLTSDTSFLETEKAKKCNIIITTPEKWDLLTRRWSDYSRLFELVKLVLVDEIHTI-KEKRGASLEVILTRMNTMCQN----IRFVALSATVPNIEDLALWLKTNNELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYNSKLIEIIEKHADNRPVLIFCPTRASTISTAKFLLNNHIFSKSKK----------RCNHNPSDKILNECMQQGIAFHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNSSEIQ--EYSDLDVLQMIGRAGRPQFETHGCAVIMTDSKMKQTYENLIHGTDVLESSLHLNLIEHLAAETSLETVYSIETAVNWLRNTFFYVRFGKNPAAYQEVNRYVSFHSVEDSQINQFCQYLLDTLVKVKIIDISNG-EYKSTAYGNAMTRHYISFESMKQF-INAKKFLSLQGILNLLATSEEFSVMRVRHNEKKLFKEINLSPLLKYPFLTEKKQSQIIDRVSQKVSLLIQYELGGLEFPSYEGASKLHQTLVQDKFLVFRHCFRLLKCMVDTF 749

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Yeast
Match: SKI2 (Ski complex component and putative RNA helicase; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, SKIV2L, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome [Source:SGD;Acc:S000004390])

HSP 1 Score: 75.0998 bits (183), Expect = 1.132e-13
Identity = 52/175 (29.71%), Postives = 89/175 (50.86%), Query Frame = 1

Query: 2218 VYEKVMEYAGKHQVL---IFVHSRKETVNTAKAIK--EKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELT 2727
             + +++ Y  K ++L   +FV S+K     A  ++    C N++   + +  +K+ T + ++D D  +    + LL  G AVHH GL    +  +E LF+   I+VL +T T A G+NLP   VI   + + + D     EL+  +  QM GRAGR   D+ G  I++   + L+
Sbjct:  613 TWPEIVNYLRKRELLPMVVFVFSKKRCEEYADWLEGINFCNNKEKSQIHMFIEKSITRLKKEDRDLPQILKTRSLLERGIAVHHGGLLPIVKELIEILFSKGFIKVLFATETFAMGLNLPTRTVIF--SSIRKHDGNGLRELTPGEFTQMAGRAGRRGLDSTGTVIVMAYNSPLS 785

HSP 2 Score: 50.447 bits (119), Expect = 3.761e-6
Identity = 45/194 (23.20%), Postives = 91/194 (46.91%), Query Frame = 1

Query: 4102 ESLYN--SDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLD-CHHTATYNFNPSVRHRPLDIEI 4674
            E++Y+    ++VF+ A T +GKTV AE AI    ++R   + +Y + +  L+  ++ ++ +TF  +   +I  TG+  ++      A+ ++ T E   + S  ++    I++++  I D++H +  Q  G   E +          L   ++ I LS ++ N  +   W+        Y  +   R  PL+I I
Sbjct:  336 EAVYHLEQGDSVFVAAHTSAGKTVVAEYAIA--MAHRNMTKTIYTSPIKALSNQKFRDFKETFDDVNIGLI--TGDVQIN----PDANCLIMTTE--ILRSMLYRGADLIRDVEFVIFDEVHYVNDQDRGVVWEEVI-------IMLPQHVKFILLSATVPNTYEFANWIGRTKQKNIYVISTPKRPVPLEINI 512

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Yeast
Match: MTR4 (ATP-dependent 3'-5' RNA helicase of the DExD/H family; involved in nuclear RNA processing and degradation both as a component of TRAMP complex and in TRAMP-independent processes; TRAMP unwinds RNA duplexes, with Mtr4p unwinding activity stimulated by Pap2p/Air2p but not dependent on ongoing polyadenylation; contains an arch domain, with two coiled-coil arms/stalks and a globular fist/KOW domain, which has RNA binding activity and is required for 5.8S rRNA processing [Source:SGD;Acc:S000003586])

HSP 1 Score: 71.2478 bits (173), Expect = 1.382e-12
Identity = 98/427 (22.95%), Postives = 171/427 (40.05%), Query Frame = 1

Query: 4105 SLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWL------DCHHTATYNFNPS-VRHRPLDI----------EIQTFNITHNATRLAAMSKPVYQTILKLSPNS-------------------------------------PVIVFVPTMKQTEEIAFLL--MGYALSDKKN-----FGRASEAIVSEYMRNISN-EILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVIM 5199
            S  +  E+V + A T +GKTV AE AI +   N+Q  R +Y + +  L+  +Y E +  FG +G     +T N +        A  +V T E   + S  ++  + ++ +   I D++H +  +  G    V+   T  +   L   +R + LS ++ NA +  EW+       CH   T NF P+ ++H               E  TF   +    +A++S  +        PNS                                     PVIVF  + +  EE+A  +  + +   D+K      F  A  A++ E  R +   + ++  L  G+G  H  L    + ++  LF    +++L  + T    +   A  V+    + ++G+   +   S  + IQM GRA    +DD   VIM
Sbjct:  159 SCIDRGESVLVSAHTSAGKTVVAEYAIAQSLKNKQ--RVIYTSPIKALSNQKYRELLAEFGDVGLMTGDITINPD--------AGCLVMTTEI--LRSMLYRGSEVMREVAWVIFDEVHYMRDKERG----VVWEETIIL---LPDKVRYVFLSATIPNAMEFAEWICKIHSQPCHIVYT-NFRPTPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASISNQIGD-----DPNSTDSRGKKGQTYKGGSAKGDAKGDIYKIVKMIWKKKYNPVIVFSFSKRDCEELALKMSKLDFNSDDEKEALTKIFNNAI-ALLPETDRELPQIKHILPLLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFATETFSIGLNMPAKTVVFTSVRKWDGQQFRW--VSGGEYIQMSGRAGRRGLDDRGIVIM 557

HSP 2 Score: 69.3218 bits (168), Expect = 5.911e-12
Identity = 70/283 (24.73%), Postives = 122/283 (43.11%), Query Frame = 1

Query: 2032 MRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQE---------YLGINER---------KAVKRIELM-------NDLVYEKVMEYAGK----------------------HQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHD-----LKDLLPY---GFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNE 2715
            +R V LSAT+PN  + AE+I     +      +++RP P++           YL ++E+         KA+  I           D   +K   Y G                       + V++F  S+++    A  + +   N D       +K+A T +    +  +   D     +K +LP    G  +HH+GL    +  +E LF +  ++VL +T T + G+N+PA  V+   T V + D  ++  +S  + +QM GRAGR   D +G+ IM+ +E
Sbjct:  287 VRYVFLSATIPNAMEFAEWICKIHSQPCHIVYTNFRPTPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASISNQIGDDPNSTDSRGKKGQTYKGGSAKGDAKGDIYKIVKMIWKKKYNPVIVFSFSKRDCEELALKMSKLDFNSDD------EKEALTKIFNNAIALLPETDRELPQIKHILPLLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFATETFSIGLNMPAKTVVF--TSVRKWDGQQFRWVSGGEYIQMSGRAGRRGLDDRGIVIMMIDE 561

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Nematostella
Match: EDO49146 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH22])

HSP 1 Score: 2212.57 bits (5732), Expect = 0.000e+0
Identity = 1124/2167 (51.87%), Postives = 1555/2167 (71.76%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQ-QKFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXX-XSESDD---GGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVIS---NYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPG--YNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLID-DPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFG-ALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDK--KNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDA-RSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDV----ILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLM----ELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEV--SKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDRRS+DE TGEV+  +  +   +MG +  + KP   EE++ KR ++          +  S+L+ +V       Y PKT ETKS YE +L+ +   + +    +I     DE+L  LK+  + DKE+ K    LLG+ + D ++  LV+L  K+TDY   + ++N++        + +  D++EEE+    ++  +SES+D   G VEA+TN TL       G +S+                QK  A+S+ L+  DIDAFWLQR L+K++ D    + +++++ E+LK A +++ELENKL+ ++G D+F  +R+LR+N+ M+ YCT L  +Q+ +E+ +IEA+M+ DP   +IL  L   D K D++  ER RK   R A+I AD++  +S+ +      G+  +LDL+ + F  GSHLM NK C+LP G+FRK +PG  Y  V VPA KPKP E  E L  I  LP Y +AAFE   TLNRIQS++ +TAL SDEN+LLCAPTGAGKTNVALLT++REIGKHIN DGTI  ++FKI+Y+APM+SLV EM  +FS+RL +Y L V+ L+GD +L++E+I+ TQIIVCTPEKWDII+RKS E+T+TQLV+L+IIDEIHLLHD+RGPVLE++VART+R ++++   +  R+VGLSATLPN ED+A F+ V+  +GLF FD+S+RPVP+EQ+++GI E+K +KR++  N++VYEKV+E+AGK+QVL+FVHSRKET  TAKA+++ CL RD+LGLFLR+  AST VL+ + ++VKN +LKDLLPYGFA+HHAG++  DR  VE+LF D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG W EL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSL+N+QLP+ESQ ISKLADNLNAE+V+G+V+   +++ WL YTYLYIRM +NP+LYG+ +  I+ DP L+    +LI++AAS+L+K  ++ +DK+SG F   E+GRIA++YY T+ET+      LK ++ +IE+F+VFS  +EF+ I VREE+K+E+ KLLE VP+P+KE  E+P  K+N LLQ++ISQLKLE F L SD  YI+QSA RL+RA+FE+ L++ WA L    L   K +++RMW    PLRQFKK+P E+ KK+EKK  P++R  D   +E+GELV+  K+GKT++K +HQ+PK+ L  H+QPITRST+ VELT+TPDF+W  K HG+S+ FWI VEDV SE ILH+EYFLLK K+  D+H++KF+V +++PLPP Y+IR VSD+W+G ET++ + F +++LPEKN P TELLDLQ LP  ALRN  +E++Y  K  +FN IQTQ F +LY+S ENVFIGAPTGSGKT+CAE A++R      + RCVYVT +  LA+  Y +W   FG  LGK V+ LTG T+ D K ++K +++VST E WDVLSRRWK++K +QN+ LFI+D+ HLIG    G  +E+ICSR RY+SSQLE  IRI+ LS SL NA+DV +WL    T  +NF+P+VR  PL++ IQ FNITH ++RL AM+KPVYQ I+K SP  P +VFVP+ +QT+ +A  ++ ++ +D   + F   +E  ++ ++  ++++ L ET++ G+ F+HE LS  E  ++ +LF+S +IQ++VVS TLC S+   A+LV+VMDTQ Y GK   Y DY   D++ M+G A+   +DDA ++VI+CQ +KK+F +KFL+EPLP+ESHLDH LHDHFNAE+VTKTIENKQDAVDYLTWTFLY RMT NPNYYNL+GV+HRHLSDH+SELVENTL DLE SKC++++D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +K+R L+E+I +A+E+  L +RH E+     +L R+   +  P     + +DP  K N+L+QA++SR+ + + EL+ D   IL K++RLIQACVDVLSSN WL PALAAMELAQM TQA W +DS LKQIPHF  P +++RC    V++VFD+M     L  +Q  + +       QDVARF   YPNI+L++E+     +  G  V++ + L R+++   +V A  FP KREE WWLV+G+        +    S  +  +L+F AP   G+Y Y L+FM D+Y+GCDQEY F I V
Sbjct:    1 MADATARSLQYEYKANSNLVLQADRSLIDRRSRDEATGEVVSLVGHLGGMRMGDKYERTKPPVSEERKAKR-QKIADKEEFAKLRGSSLLSEEVEDLTGVRYRPKTRETKSTYEVLLSFIQAAIGDQP-RDILCGAADEVLASLKDDKMKDKEKLKEIVSLLGD-MPDERFALLVNLGKKITDYTFDRDYSNDDEVIDETYGVAVQFDEDEEEEKEDFDMVRESESEDETEGMVEAETNMTLQ------GGLSE---------------SQK--ASSDTLHPRDIDAFWLQRELNKYYADAEASRSKSEEVQEILKSANDERELENKLMLLLGHDKFSFIRLLRKNRNMVLYCTLLATAQSSKEKKEIEAKMEADPDLAQILHALNETD-KGDLIQEERARKAANRKARIAADLDALESDQVRMQFTRGARKVLDLEELAFKDGSHLMANKQCQLPVGTFRKQRPGKGYEEVHVPALKPKPFETGEQLTPITSLPMYAQAAFEGYPTLNRIQSRLCETALNSDENLLLCAPTGAGKTNVALLTILREIGKHINLDGTINTEEFKIIYVAPMRSLVQEMVLNFSKRLSTYGLTVSELTGDHNLTKEQIHGTQIIVCTPEKWDIITRKSGERTFTQLVRLIIIDEIHLLHDDRGPVLESLVARTIRQIETTQELV--RLVGLSATLPNYEDVATFMRVNPAKGLFFFDNSFRPVPLEQQFIGITEKKPIKRMQATNEVVYEKVVEHAGKNQVLVFVHSRKETAKTAKAVRDMCLERDSLGLFLREDSASTEVLRSEAEQVKNGELKDLLPYGFAIHHAGMSRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWVELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLMNQQLPVESQFISKLADNLNAEVVLGSVQTAKDAVHWLGYTYLYIRMLRNPALYGISHDEIEKDPLLEQRRADLIHSAASLLDKNNLLKYDKKSGNFQVTELGRIASHYYLTHETVSTFNNLLKPTLSEIELFRVFSLSSEFKYINVREEEKLELNKLLERVPIPVKESIEEPSAKVNVLLQSFISQLKLEGFALMSDMVYITQSAGRLVRAIFEIVLNRGWAQLADKALCLSKMIDKRMWLSMTPLRQFKKIPMEVIKKIEKKEFPWERYYDLGPNEIGELVHMPKLGKTLHKLVHQLPKMELATHIQPITRSTLSVELTVTPDFQWDEKVHGNSEAFWILVEDVDSEIILHHEYFLLKAKYAQDEHVVKFFVPVFEPLPPQYFIRIVSDRWLGSETQLPVSFRHLILPEKNQPPTELLDLQPLPVSALRNPAFEALYRDKFPYFNPIQTQVFSTLYDSSENVFIGAPTGSGKTICAEFAVLRFLQQSPEGRCVYVTPIQALAEQVYADWQNKFGLQLGKNVVMLTGETSADLKLLAKGNVVVSTPEKWDVLSRRWKQRKNVQNVSLFIMDEAHLIGGD-TGPVMEIICSRMRYISSQLERTIRIVALSSSLANAKDVAQWLGVPSTGLFNFHPNVRPVPLELHIQGFNITHTSSRLIAMTKPVYQAIMKHSPKKPAVVFVPSRRQTKLLALDILTFSGADNEPQRFLHCTEDDLNPFVSRLTDKTLKETVTYGIAFLHEGLSDAEVKIVNQLFTSGAIQVVVVSRTLCLSVNLSAHLVVVMDTQFYEGKTHSYADYPVTDVLHMIGHASRPLLDDAGKAVILCQASKKEFFKKFLYEPLPIESHLDHTLHDHFNAEVVTKTIENKQDAVDYLTWTFLYRRMTLNPNYYNLQGVTHRHLSDHMSELVENTLNDLEQSKCVSVEDEMDVTPLNLGMIAAYYYINYTTIELFSVSLNAKTKLRGLVEIISSASEYAPLSIRHHEEATLKQLLNRVPHKITSP-----KFNDPHVKTNLLIQAHMSRMQL-SPELQSDTELILSKAMRLIQACVDVLSSNGWLSPALAAMELAQMATQAMWSKDSYLKQIPHFT-PDIIKRCVEKEVESVFDIMFCIITLATQQFDSTLLIITILFQDVARFCNRYPNIELSFEIPDKNQIKTGRPVNMTVDLEREDEQPGAVIAPFFPQKREEGWWLVIGDTKANRYEPLAPSISRQDTPTLDFVAPSSPGTYSYVLFFMCDAYMGCDQEYPFKITV 2130

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Nematostella
Match: EDO46714 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPC5])

HSP 1 Score: 1314.29 bits (3400), Expect = 0.000e+0
Identity = 707/1761 (40.15%), Postives = 1065/1761 (60.48%), Query Frame = 1

Query: 1345 GSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSS-EKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGK-HQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENV-LIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN--VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEK--FKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFG-ALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGY--ALSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDD-IDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKL--LERCEAAGVKTVFDLMELEDEQKLALMN-----FPDDKLQDVARFFQCYPNIDLTYEVSKSVSAG-----GQVSVQIHLARDEDNISSVYANN---------------------------FPYKREESWWLVVGEPNQGHLISIKLLS--SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 6468
            G+  +      LP  + RK    Y  V +P     P  A ++ V I+ L    + AF+  K+LNRIQS VY +A  ++EN+L+CAPTGAGKTN+A++T++REI ++I   G I+KD FKIVY+APMK+L  EM  +FS+RL    + V  L+GD  L++ EI +TQ++V TPEKWD+++RKS+ +    QLVKLLIIDE+HLLHD+RG V+E +VART+R + SS S I  RIVGLSATLPN  D+A F+ VD ++GLF FDS +RPVP+ Q ++G+      ++   M+ + YEKV E   K +QV++FVH+R  TV TA  ++E   N+    LF  ++        + + + +N  L+DL P GF  HHAG+  TDR  VE+ F    I+VLV T+TLAWGVNLPAH VIIKGT+VY   KG + +L  LDV+Q+FGRAGRPQ+D  G G +IT  + L++YLSLL  Q PIES L + L D+LNAEI +GTV N++E+++WL Y+YLYIRM KNP +YG+ +    DDPTL+N+ R LI + A  L+KA MI F +  G   + ++GR A+++Y   +T++   +  +  +   E+ ++ S   EF  I VRE++  E+++ L    V +P+K G E+   K+N LLQ YIS+ ++E F+L SD  Y++Q+ ARL+R +FE+ L + +  L   +L   K +E+R+W    PL+QF  +  EI  KLE +    ++L D    E+G LV++ +MG T+   +++ P +++   +QPITR+ ++V LTIT +FEW  ++HGSS+ +WI+VED  + +I H EY LL++K     +   L F + I++PLPP YY+ AVSD+W+G ET   I F +++LPE++ P TELLDLQ LP  AL N  YE +Y  K + FN +QTQ F ++YNSD NV +GAPTGSGKT+ AE+AI RLF     A+ VY+  L  L + R  +W   FG  LGK VI+LTG+   D++SIS+A +IV+T E WD +SR W+ +  ++ + L I+D++HL+G +  G  LEVI SRT ++SS  +  +R++GLS +L NARD+ +WL       +NF PSVR  PL++ I  F   H   R+A M+KP ++ I   SP  P +VFV + +QT   A  L+ +  A  D K +    E  + + +  + +  L   LS G+G  H  L   +R+++ ELF +Q IQ+L+ + TL W +   A+LV++  T+ ++GK C Y D+   D++QM+GRA     DD  ++VI+    KK F +KFL+EP P+ES L   L DH NAE+V  TI +KQDA+DY+TWT+ + R+  NP YY+L+   H  ++ +LS LVE+   +LE S C+   +D + +S      IA++YY+++ T+ M    L  +  +  LLE++  A E+ +LP+RH ED I + + + L L ++         TK N+L QA+ SR+ + +++   D   +L +++R++QA +DV +   WL  AL  M + QM+ QA+W  D  L  +P      L    R     ++++ +L+     +K  L N         +++ +    +  P + L+ ++  +   G      +  V+  L    DN  +V+A+                            FP  + E WWLV+G+ + G L+++K L     T   +L+F  P + G    T+Y MSDSYLG DQ+Y     V+
Sbjct:  420 GASFVAGSKIALPTDAKRKITKSYEEVSIPPSTGPPPGAGDHRVPISQLDEIGQIAFQGTKSLNRIQSIVYDSAYNTNENLLICAPTGAGKTNIAMMTIVREIKQNIE-QGVIKKDKFKIVYVAPMKALAAEMVRNFSKRLAGLGISVRELTGDMQLTKMEILKTQMLVTTPEKWDVVTRKSTGDVALAQLVKLLIIDEVHLLHDDRGSVIECLVARTLRQVLSSQSMI--RIVGLSATLPNYLDVAHFLRVDPYKGLFAFDSRFRPVPLGQTFIGVKGLNPFQQAHEMDKICYEKVTENVEKGYQVMVFVHARNATVRTAMTLREMASNQGDSMLFRAEQAPDYGSALKQVMRSRNKQLRDLFPDGFGTHHAGMLRTDRTMVEQYFAKGLIKVLVCTATLAWGVNLPAHAVIIKGTEVYDAKKGSFVDLGILDVLQIFGRAGRPQFDKFGEGTIITAHDRLSHYLSLLTRQAPIESTLTASLTDSLNAEICLGTVTNVNEAVEWLSYSYLYIRMIKNPLVYGIPHKDKEDDPTLENYRRQLIVSTARKLDKARMIRFAEEQGYLSATDLGRTASHFYIKYDTIEEFNERFRPDLAMPEILEMLSHAGEFEQIKVREDELSELEEHLHEDCVVIPVKGGVENTYGKVNILLQTYISRGRVESFSLVSDLGYVAQNGARLIRGLFEIALRRGYPVLANRLLTLSKCIEKRLWPEEHPLKQFTTLSPEILNKLEGRKASLEKLRDMVPEEIGHLVHHVRMGHTVKSCVNRFPAISIAASIQPITRTVLRVRLTITAEFEWNDRAHGSSEPWWIWVEDPENSHIYHSEYLLLQKKQVLSEEPQSLVFTIPIFEPLPPQYYVHAVSDRWLGAETVCAISFQHLILPERHPPHTELLDLQPLPISALHNVSYELLY--KFTHFNPVQTQVFHTVYNSDHNVLLGAPTGSGKTIIAELAIFRLFDKYPGAKAVYIAPLKALVRERMDDWKVRFGRKLGKRVIELTGDVTPDSRSISQADLIVTTPEKWDGISRSWQTRSYVKQVNLLIIDEIHLLGDE-RGPVLEVIVSRTNFISSHTDKKVRVVGLSTALANARDLADWLGIGSAGMFNFRPSVRPVPLEVHITGFPGKHYCPRMATMNKPTFEAIRIHSPTKPTLVFVSSRRQTRLTALDLIAFLAAQDDPKQWLHMPEEEMEQVLHAVRDSNLKLVLSFGIGLHHAGLHERDRSVVEELFVNQKIQVLIATSTLAWGVNFPAHLVVIKGTEYFDGKKCRYVDFPITDVLQMMGRAGRPQYDDQGKAVILVHDVKKHFYKKFLYEPFPVESSLLEVLADHLNAEVVAGTITSKQDAMDYMTWTYFFRRLVMNPTYYDLQDTDHDSVNKYLSRLVESAAAELELSGCLNTGEDSVSLSPTTAAHIASYYYLNHLTLRMLKERLHADCSLPDLLEVLSEAHEYSELPVRHNEDAINSDLAKELPLEVNP-HTFDSAHTKTNLLFQAHFSRLALPSSDYFTDQKSVLDQAIRILQAMIDVAADEGWLATALRIMHVGQMVVQARWLHDCSLLTLPGIQAQHLSGFRRPNGDQIQSLPELVHAVSARKSILDNALRGMVSSQEIEQIHSVLRRLPMLALSIKLRGAWEEGDGAKKAEKPVRTDLVGLHDNWVTVHADQEYAMKVSLKRLSASFRVSTDAKVHAPCFPKVQTEGWWLVLGDTDTGELMALKRLGPVQGTTTATLSFYTPEEEGRKILTVYLMSDSYLGIDQQYDLFFEVI 2173

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Nematostella
Match: EDO26736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TB80])

HSP 1 Score: 107.842 bits (268), Expect = 2.883e-27
Identity = 48/115 (41.74%), Postives = 82/115 (71.30%), Query Frame = 1

Query:  850 NSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDR 1194
            +S+ L+  DIDAFWLQR L+K++ D    + +++++ E+LK A +++ELENKL+ ++G D+F  +R+LR+N+ M+ YCT L  +Q+ +E+ +IEA+M+ DP   +IL  L   D+
Sbjct:    1 SSDTLHPRDIDAFWLQRELNKYYADAEASRSKSEEVQEILKSANDERELENKLMLLLGHDKFSFIRLLRKNRNMVLYCTLLATAQSSKEKKEIEAKMEADPDLAQILHALNETDK 115

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Nematostella
Match: EDO34884 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN39])

HSP 1 Score: 105.916 bits (263), Expect = 1.687e-23
Identity = 91/340 (26.76%), Postives = 169/340 (49.71%), Query Frame = 1

Query: 2677 YDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLK----KSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-----VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFE-VTLSKKWASLTLSVLESCKEVEQRMWACSCPL-RQFKKVPWEITKKLEKKNI-PFDRLIDQKHHELGELVNNH-KMGKTIYKYIHQIPKLNLKI 3657
            +DT    +++T   +   Y SLL+    IES L   L ++LNAEIV+ T+ ++  +++WL+ T+L+IR++KNP+ Y            D   +NL     + LE++ ++  +    +   +E G + A YY      D +K+FL     +++ D+ +  + SKC EF ++ +R  +K  +  L ++     V  P+    +    KINCL+QA +  L +  F+L+ D   I +S  R+ R + E + L   + +L  ++L + K ++ R+W  S  + RQ +KV   ++  L    +  F ++ +    E+  +VN H   G  I   +   PK  + +
Sbjct:  143 FDTSATAVILTTTTKKDKYSSLLHGTQQIESSLHRHLIEHLNAEIVLHTITDVSVALEWLKSTFLFIRIQKNPTYY------------DMCIQNL-----NTLERSNLVKMED-GFDLKPSEPGCLMARYYI---AFDSIKEFLAIQGTETLSDMVI--LLSKCKEFADVKLRVSEKRILNTLNKDKHKATVRFPVNGKIKTTDQKINCLIQATLGCLPITEFSLNQDVTKIFRSGQRVTRCLMELLMLRGDYRALQNAILVT-KCMKSRLWENSLYVSRQLEKVGMTLSTMLVNAGLTTFKKIEETNPREIELIVNRHPPFGSQIRDAVLAFPKYEVSV 458

HSP 2 Score: 100.523 bits (249), Expect = 1.030e-21
Identity = 71/238 (29.83%), Postives = 119/238 (50.00%), Query Frame = 1

Query: 5182 ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRI-----KQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVL 5880
            A +VI+  T KKD     LH    +ES L   L +H NAEIV  TI +   A+++L  TFL+ R+ +NP YY++               ++N L  LE S  + ++D  D+     G +   YYI + +I+ F L+++    +  ++ L+    EF D+ LR  E  IL  +     K ++R P++   + +D   K N L+QA L  +PI    L +D+ +I     R+ +  +++L
Sbjct:  147 ATAVILTTTTKKDKYSSLLHGTQQIESSLHRHLIEHLNAEIVLHTITDVSVALEWLKSTFLFIRIQKNPTYYDM--------------CIQN-LNTLERSNLVKMEDGFDLKPSEPGCLMARYYIAFDSIKEF-LAIQGTETLSDMVILLSKCKEFADVKLRVSEKRILNTLNKDKHKATVRFPVNGKIKTTD--QKINCLIQATLGCLPITEFSLNQDVTKIFRSGQRVTRCLMELL 366

HSP 3 Score: 52.7582 bits (125), Expect = 1.295e-6
Identity = 39/135 (28.89%), Postives = 63/135 (46.67%), Query Frame = 1

Query: 1960 RGPVLEAIVARTMRAMQSSHSNI-----------DMRIVGLSATLPNTEDIAEFIHVDKH-RGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYE---KVMEYAGKHQVLIFVHSRKETVNTAKAIKEK 2319
            RG  +EA+++R    M++  +NI            MR++ +SAT+PN EDIA ++   KH    +  D SYRPV + +  LG      +   +    L Y+    V  Y+ +   L+F  S    + T    K+K
Sbjct:   30 RGATVEAVISR----MKTVQTNITRNTNKLQFKASMRLIAISATIPNVEDIAAWLGSLKHPASSYSMDDSYRPVKLRKVVLGFPMHANMSEFKFDLSLNYKISGIVHTYSDQKPTLVFDTSATAVILTTTTKKDK 160

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Nematostella
Match: EDO44748 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUT3])

HSP 1 Score: 104.76 bits (260), Expect = 1.817e-22
Identity = 119/434 (27.42%), Postives = 189/434 (43.55%), Query Frame = 1

Query: 1510 AFEKIKTLNRIQSKVYK-TALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDS--HLSREEINETQIIVCTPEKWD-IISRKSSEKTYTQL-VKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINE-----------------RKAVKRIELMNDLVYEK--------VMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNH---DLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRP--DKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMI 2706
            A+  I+ L   Q    K  A++   N++   PT  GKT VA + MM+E+  H        KD   +V + P  S+V E   + ++        V   +G       R+   +  + + T EK + +++    EK    L + ++    +      RG  LE  +A+T+       S   ++IVG+SATL N  D+ +F+  +       + + +RPV + QEY+ ++                     V+RI    D  + K        V+E   +H  LIF  ++K   N AK + E  L R+      + K    + L Q L    N     LK  +PYG A HH+GL   +R  +E+ ++   +  L  TSTLA GVNLPA  VI++   + R    K ++         QM GRAGR   D+ G  I+I
Sbjct:   14 AYRGIQNLYEWQDACLKLPAIQEKRNLIYSLPTSGGKTLVAEILMMKELLVH-------HKD---VVLVLPFVSIVQEKVKTITQFAVELGFVVEEYAGSKGKFPPRKRRTKRALYIATIEKANSLVNSLIEEKRMDDLGLIVVDELHMLGEGGGRGATLEMCLAKTL------FSTNHIQIVGMSATLSNIGDLQKFLMAEV------YSNDFRPVEL-QEYVKVDNIVYKVPCSSSKSEADEIYVQVRRIGHSPDQRHIKDPDHLVPLVLEVIPQHSCLIFCATKKNCENVAKLMVE-FLPRE----MTQVKIGERMELLQALHHQANGLCPVLKKSVPYGIAYHHSGLTMDERKLIEDAYSQGVLCALTCTSTLAAGVNLPAKRVILRAPYIGRNIIRKSQYK--------QMIGRAGRAGIDSTGESILI 411

HSP 2 Score: 82.4185 bits (202), Expect = 1.578e-15
Identity = 100/447 (22.37%), Postives = 197/447 (44.07%), Query Frame = 1

Query: 4126 NVFIGAPTGSGKTVCAEIAIMR-LFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNM--DNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIG-SQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNP-------------------SVRHRPLDIEIQTFNITHNATRLAAMSKP--VYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVS-EYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQK-FLHEPLPLESHLDHQLHDHFNAEIVT----KTIENKQDAVDYLTWTFL 5364
            N+    PT  GKT+ AEI +M+ L  + +D   V V     + Q +     +    LG  V +  G+       K  +K  + ++T E  + L     ++K + ++ L +VD+LH++G     G TLE+  ++T + ++     I+I+G+S +L+N  D+ ++L      + +F P                   S +    +I +Q   I H+  +   +  P  +   +L++ P    ++F  T K  E +A L++ +   +  +   G   E + +  +  N    +L +++  G+ + H  L+++ER L+ + +S   +  L  + TL   +   A  VI+     Y G++ +          QM+GRA  A +D    S+++ +T  K  +   F  E    +S L +Q +       +T    K  + K + V +L+ T +
Sbjct:   39 NLIYSLPTSGGKTLVAEILMMKELLVHHKDV--VLVLPFVSIVQEKVKTITQFAVELGFVVEEYAGSKGKFPPRKRRTKRALYIATIEKANSLVNSLIEEKRMDDLGLIVVDELHMLGEGGGRGATLEMCLAKTLFSTNH----IQIVGMSATLSNIGDLQKFL-MAEVYSNDFRPVELQEYVKVDNIVYKVPCSSSKSEADEIYVQVRRIGHSPDQ-RHIKDPDHLVPLVLEVIPQHSCLIFCATKKNCENVAKLMVEFLPREMTQVKIGERMELLQALHHQANGLCPVLKKSVPYGIAYHHSGLTMDERKLIEDAYSQGVLCALTCTSTLAAGVNLPAKRVILRAP--YIGRNIIRKSQYK----QMIGRAGRAGIDSTGESILIIKTTDKHKVAPLFSGEFDSCQSSLPYQEYKGLRTLFLTLLGLKICQTKSELVSFLSRTLM 471

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Medaka
Match: snrnp200 (small nuclear ribonucleoprotein U5 subunit 200 [Source:NCBI gene;Acc:101154872])

HSP 1 Score: 2315.04 bits (5998), Expect = 0.000e+0
Identity = 1153/2155 (53.50%), Postives = 1585/2155 (73.55%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLP-IKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQ-KFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXX----XXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSK--SVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            MAD  AR++Q+EYK NSNLVL ADR+LIDR  +DEPTGEVL  +  ++  KMG +  + +P  +E++++KR KRD+    ++  K  ++L+  + +     Y PKT ET+  YE +L+ ++  L +    +I     DE+L  LKN  + DKER++  ++LLG +  DT+Y+ LV+L  K+TDY   K   N ++        ++  E D+++ +E      + + S+ D  G EA   TTL+ +    G +  V                      + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR+++ MI YCT L  +Q+  E+ +I  +M++DP+ ++IL  L+  + KEDI+  E++R+ + R +++  D+E  D++   +     +LDL+++TFTQGSH M NK C+LPDGSFRK + GY  V VPA KPK    +E LV I  LP Y +A FE  KTLNRIQSK++K+A+++DEN+L+CAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SFS+RL SY + V+ L+GD  L +EEIN TQIIVCTPEKWDII+RK  E+TYTQLV+L+IIDEIHLLHD+RGPVLE+++ART+R ++ +    D+R++GLSATLPN ED+A  + VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF+D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ+++KL D LNAEIV+G V+ + ++++WL YTYLY+RM +NP+LYG+ ++    DP L+    +LI+TAA++L+K  ++ +DKR+G F   ++GRIA+++Y T++++    + LK ++ +IE+F+VFS  +EF+NI VREE+K+E++KLLE VP+P+KE  E+P  KIN LLQA+ISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   +  CK +++RMW    PLRQFKK+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+HQ P+L+L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +E++Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+  +  + RCVY+T +  LA+  + +W + F   L K V+ LTG T+ D K + K  II+ST + WD+LSRRWK++K +QN+ LFIVD+ HLIG + NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+D+  WL C  TAT+NF+P+VR  PL++ IQ FN++H  TRL +M+KPVY  I+K SP+ P +VFVP+ +QT   A  ++ +  +D   + F   +E  +  ++  I++  L ETL+ GVG++HE LS  ER ++ +LF+S ++Q++V S +LCW I   A+LVIVMDTQ YNGK   Y DY   D++QMVG+AN   +DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH LHDHFNAEIVTKTIENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVENTL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +K+R L+E+I NA E++++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+P+F     ++RC   GV+++FD+ME+EDE +  L+   D ++ DVARF   YPNI+L YEV +  ++ +G  V VQ+ L R+E+    V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP   G + YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTKMGDKAQRTRPQNLEDRRNKRRKRDEDRHDINKMKGFTLLSEGIDEMVGIVYKPKTKETRETYEVLLSFIHAALGDQP-RDILCGAADEVLAVLKNDKIRDKERRREVEQLLGPS-DDTRYHVLVNLGKKITDYGGDKELQNMDDNIDDTYGVNVQFESDEEEGDENPFGEVQDEQSDEDSEGEEAVVTTTLSANLGETGDVMTV--------------------KKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKILRQHRRMIQYCTMLASAQSEAEKERIIGKMESDPELSKILYKLQETE-KEDIIREEQSRRERVRKSRVD-DLEAMDTDHGESVMPRQILDLEDLTFTQGSHFMANKRCQLPDGSFRKQRKGYEEVHVPALKPKAFADNEVLVSIDKLPKYAQAGFEGFKTLNRIQSKLFKSAMDTDENLLVCAPTGAGKTNVALMAMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFSKRLASYGITVSELTGDHQLCKEEINATQIIVCTPEKWDIITRKGGERTYTQLVRLIIIDEIHLLHDDRGPVLESLIARTIRNVELTQD--DVRLLGLSATLPNYEDVATCLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFSDRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVAKLPDMLNAEIVLGNVQTVKDAVNWLGYTYLYVRMLRNPTLYGISQDDRSADPLLERRRMDLIHTAANVLDKNSLVKYDKRTGAFQVTDLGRIASHFYITHDSVQTYNQLLKPTLSEIELFRVFSLSSEFKNINVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTMNLCKMIDKRMWQSMSPLRQFKKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHQFPRLDLAVHLQPITRSTLKVELTITPDFQWDDKIHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLVTFFVPVFEPLPPQYFIRMVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVTALRNSAFEALYQNKFPFFNPIQTQVFNAVYNSDDNVFVGAPTGSGKTICAEFAILRMLLHNTEGRCVYITPMEALAEQVFVDWHQKFQDILNKKVVLLTGETSTDLKLLGKGDIIISTPDKWDILSRRWKQRKNVQNVSLFIVDEAHLIGGE-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDMAHWLGCSTTATFNFHPNVRPVPLELHIQGFNVSHTQTRLLSMAKPVYHAIMKHSPSKPAVVFVPSRRQTRLTAIDILTFCAADVVPQRFLHCTEKDLVPFLEKINDPTLKETLANGVGYLHEGLSATERKIVEQLFNSGAVQVVVSSRSLCWGISISAHLVIVMDTQYYNGKIHAYVDYPIYDVLQMVGKANRPMLDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGMSHRHLSDHLSELVENTLHDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKIRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPYFTSEH-IKRCTDKGVESIFDIMEMEDEDRSGLLQLTDAQMADVARFCNRYPNIELAYEVVERDNIKSGSPVLVQVQLEREEEVTGPVVAPLFPQKREEGWWVVIGDPKSNSLISIKRLTLQQKAKVKLDFVAP-AMGIHNYTLYFMSDAYMGCDQEYKFSVDV 2124

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Medaka
Match: snrnp200 (small nuclear ribonucleoprotein U5 subunit 200 [Source:NCBI gene;Acc:101154872])

HSP 1 Score: 2257.64 bits (5849), Expect = 0.000e+0
Identity = 1111/2054 (54.09%), Postives = 1519/2054 (73.95%), Query Frame = 1

Query:  340 YAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXX----XXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGV-ENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSK--SVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            Y PKT ET+  YE +L+ ++  L +    +I     DE+L  LKN  + DKER++  ++LLG +  DT+Y+ LV+L  K+TDY   K   N ++        ++  E D+++ +E      + + S+ D  G EA   TTL+ +    G +  V                      + L+  DIDAFWLQR LS+ + D    QK+  ++LE+LK A +D+E EN+L+ ++G + FD +++LR+++ MI YCT L  +Q+  E+ +I  +M++DP+ ++IL  L+  + KEDI+  E++R+ + R +++  D+E  D++   +     +LDL+++TFTQGSH M NK C+LPDGSFRK + GY  V VPA KPK    +E LV I  LP Y +A FE  KTLNRIQSK++K+A+++DEN+L+CAPTGAGKTNVAL+ M+REIGKHIN DGTI  DDFKI+YIAPM+SLV EM  SFS+RL SY + V+ L+GD  L +EEIN TQIIVCTPEKWDII+RK  E+TYTQLV+L+IIDEIHLLHD+RGPVLE+++ART+R ++ +    D+R++GLSATLPN ED+A  + VD  +GLF FD+S+RPVP+EQ Y+GI E+KA+KR ++MN++VYEK+ME+AGK+QVL+FVHSRKET  TA+AI++ CL +DTLGLFLR+  AST VL+ + ++ KN +LKDLLPYGFA+HHAG+   DR  VE+LF+D+HIQVLVST+TLAWGVNLPAH VIIKGTQVY P+KG WTEL ALD++QM GRAGRPQYDTKG GI+IT+  EL YYLSLLN+QLPIESQ+++KL D LNAEIV+G V+ + ++++WL YTYLY+RM +NP+LYG+ ++    DP L+    +LI+TAA++L+K  ++ +DKR+G F   ++GRIA+++Y T++++    + LK ++ +IE+F+VFS  +EF+NI VREE+K+E++KLLE VP+P+KE  E+P  KIN LLQA+ISQLKLE F L +D  Y++QSA RLMRA+FE+ L++ WA LT   +  CK +++RMW    PLRQFKK+P E+ KK+EKKN PF+RL D  H+E+GEL+   KMGKTI+KY+HQ P+L+L +HLQPITRST+KVELTITPDF+W  K HGSS+ FWI VEDV SE ILH+EYFLLK K+  D+H++ F+V +++PLPP Y+IR VSD+W+  ET++ + F +++LPEK  P TELLDLQ LP  ALRN  +E++Y  K  FFN IQTQ F ++YNSD+NVF+GAPTGSGKT+CAE AI+R+  +  + RCVY+T +  LA+  + +W + F   L K V+ LTG T+ D K + K  II+ST + WD+LSRRWK++K +QN+ LFIVD+ HLIG + NG  LEVICSR RY+SSQ+E PIRI+ LS SL+NA+D+  WL C  TAT+NF+P+VR  PL++ IQ FN++H  TRL +M+KPVY  I+K SP+ P +VFVP+ +QT   A  ++ +  +D   + F   +E  +  ++  I++  L ETL+ GVG++HE LS  ER ++ +LF+S ++Q++V S +LCW I   A+LVIVMDTQ YNGK   Y DY   D++QMVG+AN   +DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH LHDHFNAEIVTKTIENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVENTL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +K+R L+E+I NA E++++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+P+F     ++RC   GV+++FD+ME+EDE +  L+   D ++ DVARF   YPNI+L YEV +  ++ +G  V VQ+ L R+E+    V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP   G + YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:   19 YKPKTKETRETYEVLLSFIHAALGDQP-RDILCGAADEVLAVLKNDKIRDKERRREVEQLLGPS-DDTRYHVLVNLGKKITDYGGDKELQNMDDNIDDTYGVNVQFESDEEEGDENPFGEVQDEQSDEDSEGEEAVVTTTLSANLGETGDVMTV--------------------KKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKILRQHRRMIQYCTMLASAQSEAEKERIIGKMESDPELSKILYKLQETE-KEDIIREEQSRRERVRKSRVD-DLEAMDTDHGESVMPRQILDLEDLTFTQGSHFMANKRCQLPDGSFRKQRKGYEEVHVPALKPKAFADNEVLVSIDKLPKYAQAGFEGFKTLNRIQSKLFKSAMDTDENLLVCAPTGAGKTNVALMAMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFSKRLASYGITVSELTGDHQLCKEEINATQIIVCTPEKWDIITRKGGERTYTQLVRLIIIDEIHLLHDDRGPVLESLIARTIRNVELTQD--DVRLLGLSATLPNYEDVATCLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFSDRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVAKLPDMLNAEIVLGNVQTVKDAVNWLGYTYLYVRMLRNPTLYGISQDDRSADPLLERRRMDLIHTAANVLDKNSLVKYDKRTGAFQVTDLGRIASHFYITHDSVQTYNQLLKPTLSEIELFRVFSLSSEFKNINVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTMNLCKMIDKRMWQSMSPLRQFKKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHQFPRLDLAVHLQPITRSTLKVELTITPDFQWDDKIHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLVTFFVPVFEPLPPQYFIRMVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVTALRNSAFEALYQNKFPFFNPIQTQVFNAVYNSDDNVFVGAPTGSGKTICAEFAILRMLLHNTEGRCVYITPMEALAEQVFVDWHQKFQDILNKKVVLLTGETSTDLKLLGKGDIIISTPDKWDILSRRWKQRKNVQNVSLFIVDEAHLIGGE-NGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDMAHWLGCSTTATFNFHPNVRPVPLELHIQGFNVSHTQTRLLSMAKPVYHAIMKHSPSKPAVVFVPSRRQTRLTAIDILTFCAADVVPQRFLHCTEKDLVPFLEKINDPTLKETLANGVGYLHEGLSATERKIVEQLFNSGAVQVVVSSRSLCWGISISAHLVIVMDTQYYNGKIHAYVDYPIYDVLQMVGKANRPMLDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGMSHRHLSDHLSELVENTLHDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKIRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPYFTSEH-IKRCTDKGVESIFDIMEMEDEDRSGLLQLTDAQMADVARFCNRYPNIELAYEVVERDNIKSGSPVLVQVQLEREEEVTGPVVAPLFPQKREEGWWVVIGDPKSNSLISIKRLTLQQKAKVKLDFVAP-AMGIHNYTLYFMSDAYMGCDQEYKFSVDV 2041

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BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Medaka
Match: ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:NCBI gene;Acc:101173332])

HSP 1 Score: 1287.71 bits (3331), Expect = 0.000e+0
Identity = 660/1573 (41.96%), Postives = 1011/1573 (64.27%), Query Frame = 1

Query: 1324 KNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKS-SEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYA-GKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLID-DPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN-VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGS-SQGFWIFVEDVMSENILHYEYFLLKEK---FKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEW-MKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD--KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIK-DDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKL 6003
            K   F  G+ L+      LP+G  R+       V +P   P P+  +E  V I++L    +  F+ +K LNRIQS V++TA  ++EN+L+CAPTGAGKTN+A+LT++ EI +H+   G I+KD+FKIVY+APMK+L  EM N FS+RL+   + V  L+GD  L++ EI  TQ++V TPEKWD+++RKS  + + +Q+V+LLI+DE+HLLH++RGPVLE++VART+R ++S+ S I  RI+GLSATLPN  D+A F+HV+ + GLF FD  +RPVP+ Q ++GI     +++I  + ++ Y KV+E     HQV++FVH+R  TV TA A+ E   N   +  F  D+ +     ++ + + +N  +K++ P GF +HHAG+  +DR+ +E LF+  +++VLV T+TLAWGVNLPAH VIIKGTQ+Y   +G + +L  LDVMQ+FGRAGRPQ+D  G G +IT  ++L++YL+LL +Q PIESQ +S LADNLNAEI +GTV N+ E++ WL YTYLY+RMR NP  YG+ +  I  DPTL+     L+  +   L+KA MI F++R+G F S ++GR A+++Y    T++   +       + ++  + SK  EF  + VREE+  E+ ++  N   +    G E+   K+N LLQ YIS+  ++ F+L SD +Y++Q+AAR+MRA+FE+ L K+W ++T  +L  CK +++R+W  + PLRQF  +   +  +LE+K +  D+L + +  E+G ++++  +G T+ + +HQIP + ++  +QPITR+ ++V L +TPDF W  + HGS  + +W++VED ++++I H EYFLL++K    K   H++ F + I++PLP  YYIRAVSD+W+G E    I F N++LPE++ P TELLDLQ LP  ALRN EYES+Y  K + FN IQTQ F +LY++D NV +GAPTGSGKT+ AE+A+ R+F+    ++ VY+  L  L + R  +W ++    LGK V++LTG+   D ++I++A +IV+T E WD +SR W+ +  +Q + + I+D++HL+G +  G  LEVI SRT ++SS     +R++GLS +L NARD+ +WL       +NF PSVR  PL++ I  F   H   R+A+M+KP +Q I   SP  PV++FV + +QT   A  L+ Y  ++   K +    E  + + +  + +  L  TL+ G+G  H  L   +R  + ELF +  IQ+LV + TL W +   A+LV+V  T+ Y+GK   Y DY   D++QM+GRA     D+  ++VI+    KKDF +KFL+EP P+ES L   L DH NAEI   TI +KQDA+DY+TWT+ + R+  NP+YY+L   SH  ++ +LS LVE +L DLE S CI IK D+  V  +  G IA++YY+ + ++ MF   L+    +  LL ++ +A E+ +LP+RH ED + +++ Q L L ++          K ++LLQA+ SR  +  ++   D   +L  ++R+ QA +DV ++  WL  A++   L QM+ Q +W  DS L  +PH  +  L
Sbjct:  272 KAPAFVGGARLL------LPEGIRRENNKMCEEVEIPPNDPMPVGFEEKPVYISELDEIGQLVFKGMKRLNRIQSIVFETAYNTNENLLICAPTGAGKTNIAMLTVLHEIRQHLQPGGVIKKDEFKIVYVAPMKALAAEMTNYFSKRLEPLGITVKELTGDMQLTKGEILRTQMLVTTPEKWDVVTRKSVGDVSLSQIVRLLILDEVHLLHEDRGPVLESLVARTIRQVESTQSMI--RILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFVGIKTTNKIQQIHDIEEVCYNKVLEQVKAGHQVMVFVHARNATVRTAMALIEMAKNHGEICFFQTDQGSDYGQCEKQVQRSRNKQMKEMFPEGFGIHHAGMLRSDRSLMESLFSKGYLKVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGAFVDLGILDVMQIFGRAGRPQFDKFGEGTIITTHDKLSHYLTLLTQQNPIESQYLSSLADNLNAEIALGTVTNVEEAVKWLSYTYLYVRMRANPLAYGINHKAIQMDPTLELFRTELVVESGRRLDKAHMIRFEERTGYFASTDLGRTASHFYIRYNTIETFNELFSSQNTEADILNIVSKAEEFEQLKVREEELEELDQMQVNFCELLAAGGVENSYGKVNILLQTYISRGDVDSFSLISDLSYVAQNAARIMRALFEIALRKRWPAMTYRLLTLCKVIDKRLWGFAHPLRQFPNLSHIVLNRLEEKKLTVDKLKEMRKDEIGHMLHHVNIGLTVKQCVHQIPSILMEASIQPITRTVLRVRLMVTPDFRWNDQVHGSVGEPWWLWVEDPINDHIYHSEYFLLQKKQVVSKEPQHVV-FTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQNLVLPERHPPHTELLDLQPLPVIALRNPEYESLY--KFTHFNPIQTQIFHTLYHTDTNVLLGAPTGSGKTIAAEMAMFRVFNKYPSSKVVYIAPLKALVRERMEDWKIRIQEKLGKKVVELTGDVTPDVRAIAQADLIVTTPEKWDGVSRSWQNRSYVQKVAILIIDEIHLLG-EDRGPVLEVIVSRTNFISSHTSKSVRVVGLSTALANARDLADWLGIKQVGLFNFRPSVRPVPLEVHIHGFPGQHYCPRMASMNKPTFQAIRSHSPAKPVLIFVSSRRQTRLTALDLIAYLATEDNPKQWLHQDEREIEDIIATVRDSNLKLTLAFGIGLHHAGLHERDRKTVEELFVNCKIQVLVATSTLAWGVNFPAHLVVVKGTEYYDGKSRRYVDYPITDVLQMMGRAGRPQFDEQGKAVILVHDIKKDFYKKFLYEPFPVESSLLSVLSDHLNAEIAAGTISSKQDAMDYITWTYFFRRLVMNPSYYSLADTSHESINKYLSNLVEQSLRDLEISHCIEIKEDERTVEPLTYGRIASYYYLKHQSVGMFKERLRAELLIPELLSILTDAEEYAELPVRHNEDQLNSQLAQQLPLQVN-PHSFDSAHAKTHLLLQAHFSRAQLPCSDYSTDTKTVLDNAIRICQAMLDVAANEGWLVTAISICNLVQMVVQGRWLHDSSLLTLPHIEQQHL 1831

HSP 2 Score: 246.514 bits (628), Expect = 6.886e-65
Identity = 209/797 (26.22%), Postives = 366/797 (45.92%), Query Frame = 1

Query: 4036 EEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSN---------RQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAI-QNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCH-HTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTIL-KLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGR---------ASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRH------LSDHLSELVENTLMDLENSKCIAIKDDID-VSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYE--VSKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKRE------ESWWLVVGEPNQGHL 6315
            +E   +  K M   N IQ+  FE+ YN++EN+ I APTG+GKT  A + ++              + + + VYV  +  LA      + K    LG TV +LTG+  +    I +  ++V+T E WDV++R+     ++ Q ++L I+D++HL+  +  G  LE + +RT       ++ IRI+GLS +L N  DV  +L  + +   + F+   R  PL         T+   ++  + +  Y  +L ++     V+VFV     T   A  L+  A    KN G          +      + ++   N+ + E    G G  H  +  ++R+LM  LFS   +++LV + TL W +   A+ VI+  TQ+Y+ K   + D   +D++Q+ GRA     D      I+   +K       L +  P+ES     L D+ NAEI   T+ N ++AV +L++T+LY RM  NP  Y   G++H+       L    +ELV  +   L+ +  I  ++     ++ +LG  A+ +YI Y TIE F+      +    +L ++  A EFE L +R  E   L +++ +    +     + +   K NILLQ Y+SR  + +  L  DL+ +   + R+++A  ++    RW       + L ++I +  W     L+Q P+ +   +L R E               E+KL +    + +  ++      + NI LT +  V +  S   + S+Q  + R    +  +   +F +  +      E WWL V +P   H+
Sbjct:  322 DEIGQLVFKGMKRLNRIQSIVFETAYNTNENLLICAPTGAGKTNIAMLTVLHEIRQHLQPGGVIKKDEFKIVYVAPMKALAAEMTNYFSKRLEPLGITVKELTGDMQLTKGEILRTQMLVTTPEKWDVVTRKSVGDVSLSQIVRLLILDEVHLL-HEDRGPVLESLVARTIRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFVGIKTTNKIQQIHDIEEVCYNKVLEQVKAGHQVMVFVHARNATVRTAMALIEMA----KNHGEICFFQTDQGSDYGQCEKQVQRSRNKQMKEMFPEGFGIHHAGMLRSDRSLMESLFSKGYLKVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGAFVDLGILDVMQIFGRAGRPQFDKFGEGTIITTHDKLSHYLTLLTQQNPIESQYLSSLADNLNAEIALGTVTNVEEAVKWLSYTYLYVRMRANPLAY---GINHKAIQMDPTLELFRTELVVESGRRLDKAHMIRFEERTGYFASTDLGRTASHFYIRYNTIETFNELFSSQNTEADILNIVSKAEEFEQLKVREEELEELDQMQVNF-CELLAAGGVENSYGKVNILLQTYISRGDVDSFSLISDLSYVAQNAARIMRALFEIALRKRWPAMTYRLLTLCKVIDKRLWGFAHPLRQFPNLSH-IVLNRLE---------------EKKLTVDKLKEMRKDEIGHMLH-HVNIGLTVKQCVHQIPSILMEASIQ-PITRTVLRVRLMVTPDFRWNDQVHGSVGEPWWLWVEDPINDHI 1091

HSP 3 Score: 68.1662 bits (165), Expect = 1.129e-10
Identity = 33/76 (43.42%), Postives = 47/76 (61.84%), Query Frame = 1

Query: 6244 ANNFPYKREESWWLVVGEPNQGHLISIKLLSSPTEK--VSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            A  FP  ++E W+LV+GE ++  L+++K +     +   S+ F  P K G Y YTLY MSDSYLG DQ+Y   +NV
Sbjct: 1963 APRFPKVKDEGWFLVLGEVDRRELLAVKRVGYVRSRTVASVAFYTPEKPGRYIYTLYVMSDSYLGLDQQYDLHLNV 2038

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Medaka
Match: snrnp200 (small nuclear ribonucleoprotein U5 subunit 200 [Source:NCBI gene;Acc:101154872])

HSP 1 Score: 551.592 bits (1420), Expect = 5.102e-178
Identity = 268/455 (58.90%), Postives = 352/455 (77.36%), Query Frame = 1

Query: 5113 YDDYSAVDLIQMVGRANHASMDD-ARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSK--SVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLS-SPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINV 6465
            Y DY   D++QMVG+AN   +DD  R VIMCQ +KKDF +KFL+EPLP+ESHLDH LHDHFNAEIVTKTIENKQDAVDYLTWTFLY RMT+NPNYYNL+G+SHRHLSDHLSELVENTL DLE SKCI+I+D++DV+ +NLGMIA +YYI+YTTIE+FS+SL   +K+R L+E+I NA E++++P+RH ED +L ++ Q +   ++ + + +DP  K N+LLQA+LSR+ + +AEL+ D  +IL K++RLIQACVDVLSSN WL PALAAMELAQM+TQA W +DS LKQ+P+F   + ++RC   GV+++FD+ME+EDE +  L+   D ++ DVARF   YPNI+L YEV +  ++ +G  V VQ+ L R+E+    V A  FP KREE WW+V+G+P    LISIK L+     KV L+F AP   G + YTLYFMSD+Y+GCDQEY+F+++V
Sbjct:    5 YVDYPIYDVLQMVGKANRPMLDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGMSHRHLSDHLSELVENTLHDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKIRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLN-NPKFNDPHVKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPYFTS-EHIKRCTDKGVESIFDIMEMEDEDRSGLLQLTDAQMADVARFCNRYPNIELAYEVVERDNIKSGSPVLVQVQLEREEEVTGPVVAPLFPQKREEGWWVVIGDPKSNSLISIKRLTLQQKAKVKLDFVAP-AMGIHNYTLYFMSDAYMGCDQEYKFSVDV 455

HSP 2 Score: 150.984 bits (380), Expect = 5.878e-38
Identity = 120/453 (26.49%), Postives = 216/453 (47.68%), Query Frame = 1

Query: 2638 DVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGA-EDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIP--FDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMK--------VEL---------TITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETE 3936
            DV+QM G+A RP  D +G  +++   ++  ++   L E LP+ES L   L D+ NAEIV  T+ N  +++D+L +T+LY RM +NP+ Y ++   +    L +H   L+      LE+++ I+ +        N +G IAAYYY    T+++    L        + ++ S  AE++NI +R  +   +++L + VP  +      DP  K N LLQA++S+++L    L SDT  I   A RL++A  +V  S  W S  L+ +E  + V Q MW+    L+Q      E  K+   K +   FD +  +     G L         + ++ ++ P  N+++  + + R  +K        V+L          + P F          +G+W+ + D  S +++  +   L++K K     +   + I++     Y +  +SD ++G + E
Sbjct:   12 DVLQMVGKANRPMLDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQG--MSHRHLSDHLSELVENTLHDLEQSKCISIEDEMDVAPLN-LGMIAAYYYINYTTIELFSMSLNAKTKIRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSA-ELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPYFTSEHIKRCTDKGVESIFDIMEMEDEDRSGLLQLTDAQMADVARFCNRYP--NIELAYEVVERDNIKSGSPVLVQVQLEREEEVTGPVVAPLF-----PQKREEGWWVVIGDPKSNSLISIKRLTLQQKAKVKLDFVAPAMGIHN-----YTLYFMSDAYMGCDQE 448

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Medaka
Match: hfm1 (helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-061207-43])

HSP 1 Score: 259.61 bits (662), Expect = 5.780e-72
Identity = 221/747 (29.59%), Postives = 369/747 (49.40%), Query Frame = 1

Query: 1504 KAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSRE-EINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXX-XXRGPVLEAIVAR-----TMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLF-KFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEK---VMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKD---LLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLK----KSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXN----VPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMR-AMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPL-RQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNH-KMGKTIYKYIHQIPKLNLKIHLQP 3669
            ++ F +    N +QS+     L +++N + CAPTG+GKT +  L ++R +   + T    R  D K VY AP+K+L ++   +++++     L    L+GD+ +    EI ++ II+ TPEKWD ++RK  +    QLV+L +IDE+H++    RG  LE +V+R     + R  Q+  + + MR V +SAT+PN  DIAE++  +     +   + S+RPV + +  LG          +    L Y+    +  Y+ +   L+F  +RK    +A              +  +D + +  +  + L K  N  L     L+P G   HHAGL  +DR  VEE FT   + VL +T TLA GVNLPAH+V+IK T  Y    G   E S  D++QM GRAGRPQ+DT    +++T       Y+ L+N    IES L   L ++LNAEIV+ T+ +++ ++DW+R T+LYIR  KNP+ Y               C   + + +SI    ++I+ D+     I    GR+ A  YC     D +K+F K    +S+ D+   ++ SK  EF  I +R  +K  +    ++       P+K   +    K+N L+QA +  + ++ F L+ DTA I +   R+ + + F    S+   +  L+ +   K  + ++W  S  + +Q +K+       +      F ++      EL  ++N H   G  I   +  +PK ++ +   P
Sbjct:    4 RSVFSEFPFFNYVQSQALDDVLYTNKNFVACAPTGSGKTVLFELAIIRLL---METQEPWR--DVKAVY-APIKALCSQCFENWNKKFGHLGLICKELTGDTEIEDFFEIQDSNIILTTPEKWDSLTRKWRDNCLLQLVRLFLIDEVHVVKDATRGATLEVVVSRMKAVHSFRTSQNPEAGLSMRFVAVSATIPNVSDIAEWLSNEGEPATYLNMNESHRPVKLRKVVLGFPCSPNQTEFKFDLSLSYKMANIIQTYSDQKPALVFCSTRKGAQQSA-------------AILAKDVRFNLSIEHKQLTKYANSVLDSKLRLVPLGIGFHHAGLDLSDRKLVEEAFTQGDLSVL-TTRTLAMGVNLPAHLVVIKSTMQYVV--GSCEEYSEADILQMIGRAGRPQFDTSATAVIMTKVQTRDKYMKLMNGVEVIES-LHGHLVEHLNAEIVLQTISDVNMALDWIRSTFLYIRALKNPTHY--------------LCLKNLNSLSSI----DLISMDEDIN--IKPTAGRLMA-RYCV--AFDTMKQFSKVDGSESLSDL--VELVSKSKEFSEIQLRVNEKRPLNSFNKDKNRTTIFPLKGKMKSSDMKVN-LIQAQLGCISIQDFGLTQDTAKIFRIGLRISKLSEFLGQRSRAGFTALLNSIILAKCFQSKLWENSPYVSKQLEKIQTLSAAMVNAGLTTFTKIEQINPRELELILNRHPPFGNQIRDSVMHLPKYDVCVEQLP 701

HSP 2 Score: 233.802 bits (595), Expect = 2.246e-63
Identity = 176/632 (27.85%), Postives = 307/632 (48.58%), Query Frame = 1

Query: 4039 EYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQ----DARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNM-DNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSS-------QLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIE--IQTFNITHNATRLA---AMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLL---MGYALS-DKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQ----SLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRL 5856
            ++ S++S+   FFN +Q+Q  + +  +++N    APTGSGKTV  E+AI+RL    Q    D + VY   +  L    +  W K FG LG    +LTG+T + D   I  ++II++T E WD L+R+W+    +Q ++LF++D++H++     G TLEV+ SR + + S       +    +R + +S ++ N  D+ EWL          N +  HRP+ +   +  F  + N T      ++S  +   I   S   P +VF  T K  ++ A +L   + + LS + K   + + +++   +R          +  G+GF H  L +++R L+ E F+   + +L  + TL   +   A+LV++  T  Y    C  ++YS  D++QM+GRA     D  A +VIM +   +D   K ++    +ES L   L +H NAEIV +TI +   A+D++  TFLY R  +NP +Y                L    L  L +   I++ +DI++     G +   Y + + T++ FS  +  +  +  L+EL+  + EF ++ LR  E   L    +    +   P+    + SD +     L+QA L  + I+   L +D  +I    +R+
Sbjct:    2 KFRSVFSE-FPFFNYVQSQALDDVLYTNKNFVACAPTGSGKTVLFELAIIRLLMETQEPWRDVKAVY-APIKALCSQCFENWNKKFGHLGLICKELTGDTEIEDFFEIQDSNIILTTPEKWDSLTRKWRDNCLLQLVRLFLIDEVHVVKDATRGATLEVVVSRMKAVHSFRTSQNPEAGLSMRFVAVSATIPNVSDIAEWLSNEGEPATYLNMNESHRPVKLRKVVLGFPCSPNQTEFKFDLSLSYKMANIIQTYSDQKPALVFCSTRKGAQQSAAILAKDVRFNLSIEHKQLTKYANSVLDSKLR---------LVPLGIGFHHAGLDLSDRKLVEEAFTQGDLSVL-TTRTLAMGVNLPAHLVVIKSTMQYVVGSC--EEYSEADILQMIGRAGRPQFDTSATAVIMTKVQTRDKYMKLMNGVEVIES-LHGHLVEHLNAEIVLQTISDVNMALDWIRSTFLYIRALKNPTHY----------------LCLKNLNSLSSIDLISMDEDINIKP-TAGRLMARYCVAFDTMKQFS-KVDGSESLSDLVELVSKSKEFSEIQLRVNEKRPLNSFNKDKNRTTIFPLKGKMKSSDMKVN---LIQAQLGCISIQDFGLTQDTAKIFRIGLRI 597

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Planmine SMEST
Match: SMESG000004936.1 (SMESG000004936.1)

HSP 1 Score: 4312.3 bits (11183), Expect = 0.000e+0
Identity = 2139/2142 (99.86%), Postives = 2140/2142 (99.91%), Query Frame = 1

Query:   43 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLPIKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQKFNYAPKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFXXXXXXXXXXLHXXXXXXXXXXXXXXXXXXXXSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKSVSAGGQVSVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 6468
            MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLPIKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQKFNYAPKTAETKSVYE MLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFTNENNDDTNDLHIEIDDDQEEEEDDVYGEVQDSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKLLIIDEIHLLHDERGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVREEDKIEIKKLLENVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKSVS GGQVSVQIHLARDEDNISSVYAN+FPYKREESWWLVVGEPNQGHLISIKLLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV
Sbjct:    1 MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLPIKDIDPKKMGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQKFNYAPKTAETKSVYETMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDKERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFTNENNDDTNDLHIEIDDDQEEEEDDVYGEVQDSESDDGGVEADTNTTLNISQFAAGTISQVPGTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQKRTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKLLIIDEIHLLHDERGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVREEDKIEIKKLLENVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKKVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENILHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVFDLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKSVSPGGQVSVQIHLARDEDNISSVYANHFPYKREESWWLVVGEPNQGHLISIKLLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 2142

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Planmine SMEST
Match: SMESG000072466.1 (SMESG000072466.1)

HSP 1 Score: 1189.87 bits (3077), Expect = 0.000e+0
Identity = 675/1701 (39.68%), Postives = 1043/1701 (61.32%), Query Frame = 1

Query:  955 ILEVLKIAKNDQELENKLLRIVGVDRFDLVR--MLRENKLMIYYCTKLCCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAP--KPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKT-YTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRPVPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAG-KHQVLIFVHSRKETVNTAKAIKEKCLNRDTLG-----LFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLLNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKNPSLYGVE-NVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPI-KEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFK-KVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPKLNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSS-QGFWIFVEDVMSENILHYEYFLL---KEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEITIVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALNDLAQLRYTEWMKTF-GALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWL--DCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKK--NFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMD-DARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHFNAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLSELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSD-PRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQIP 5982
            I  +L  +KN+ EL+N+L  ++G++ F+++   +LR N+L+  +        + +    I  E+  +P          N++RK     A++ ++T   +   +A  +   S    +Y  V   DL N    Q + ++  +   LP  +  K    Y  + + A   K + L  D   V+I DL    +  FE IK LN IQS V+K A  S+EN+L+ APTGAGKTN+A+LT++ +I +HI   G I+ D+FKI+Y+APMK+L  EM  SFS+RL+S  + V   +GD  L+++EI +TQ+IV TPEK+D+I+RKS+  T   QLVKLLIIDE+HLLH++RG V+E+IVART+R ++S+   I  RIVGLSATLPN  D+AEF+ V+  +GLF FDS +RPVP+ Q ++GI    A    E +N+  Y+K++E+   K QV+IFVH+R +T  TA  ++     R  +G     LF  D K +     + +DK ++  LKD+ P G A HHAG+  +DR+FVE+ F   +I++L  T+TLAWGVNLPAH VIIKGTQ+Y  +K  + +L  LDV+Q+FGRAGRPQ+D +G GI++  +++L +YLSL+    PIES+ +  L DNLNAEI +GTV N+ E++ WL YTYLY+RM KNP  YG++   + +D TL +   +LI  +A  L+K ++I FD+RSG   S + GR+ ++YY   ET   L+     S+ + EVF++ S+ +EF  + VR+E+  E+ ++ E   V + ++G  D   K+N LLQ+YI + + + F+L SD  +I+Q+A R++R +FE  +   WA +T  +L+ CK +E R+W    P+ +F   +P E   +++ K +  + +++    EL +++     GK +      IP++++ + +QP+TR+ +++   I P F W  K HGS  Q FW++VED  S+ I+HY   +    K+  + +   + F + I++P+P  Y +R VS+ WIG ++   I F N++LPE + P T LLDL+ LP  AL+NE+Y+  Y+   S FN IQTQ F +LY SD NV +GAPTGSGKTV AE+A+ R+F+ + + + VY+  L  L + R  +W K F   L K V++LTG+   D K+++++ +IV+T E WD +SR W+++K +Q++ L ++D++HL+G +  G  LEVI SRT ++++  +  +RIIGLS +L NARD+ +WL  D +    YNF PSVR  PL I IQ F+  H   R+A M+KP+YQ I   S   PV++FV + +QT   AF L+ +A+S  K   +   S       ++NI +  L   LS G+G  H  L   +R L+  LF +Q IQIL+ + TL W +   A+LV+V  T+ ++GK   Y DY   D++QM+GRA     D + ++VIM    KK+F +KFL+EP P+ES L   L DH NAEI+  +I +KQ A++YLTWTF Y R+  NPNYY+L+ V H+ ++ +LS L+EN + +LE S+CI   +   +    +G IA++YY+ + ++ +F   LK +S +  LL+++ +  EF +LP+RH E+ +   + +  ++PI  D    D P TK N+LLQAY SRV +   +   D   +L +++R++QA +D   S  WL   L    + QM+ Q  W  D  L Q+P
Sbjct:  240 IKNLLSSSKNNDELQNELFDLIGMEGFEIISELLLRRNELVDNF--------SKQNYVDIVDELLHNPS--------LNLERK-----AKKLQQTPTGNMYKEASTKFVGSTKNIHYPHV--YDL-NAELQQTASMINGQKIYLPKSAIIKELNIYKSIELKADLNKIEALRVDR--VQIKDLDQIAQMGFEGIKQLNLIQSVVFKAAYGSNENLLISAPTGAGKTNIAMLTVLHQIKQHIGLGGKIKTDEFKIIYVAPMKALAAEMTESFSKRLRSLGISVRECTGDMQLTKQEITKTQMIVTTPEKYDVITRKSTGDTALVQLVKLLIIDEVHLLHEDRGSVIESIVARTLRQVESNQKVI--RIVGLSATLPNYLDVAEFLRVNPEKGLFYFDSRFRPVPLHQTFIGIKGENARTVKENLNETCYQKMLEFIKRKQQVMIFVHARNDTQRTATFLRNTLKERGDIGYVTEELFNNDFKIAL----KRVDKSRDMALKDVFPDGLACHHAGMLRSDRSFVEQQFVAGNIRILCCTATLAWGVNLPAHAVIIKGTQIYDAEKSSFVDLGILDVLQIFGRAGRPQFDKEGHGIIMCKQDKLNHYLSLIMRSHPIESRFMRSLNDNLNAEIALGTVTNVEEAVKWLSYTYLYVRMPKNPLNYGIKWEEIKNDHTLRDFRESLIIESARSLDKTKLIRFDERSGFLTSTDSGRLTSHYYIRFETASQLEDDFCSSLLNEEVFQIISRSSEFSQMKVRDEELSELIEMYEGCHVELMQDGCTDVAGKVNILLQSYIDRYQPQSFSLVSDLNFITQNAGRIVRYIFEKAIRNGWAMMTDRLLKLCKCIEHRIWDGYSPIWRFAGDIPDEAIHRIDNKRLSIEDILNIPVKELDDIIRYGNKGKDVKVVASFIPRVDVNVEVQPVTRTILRLRSKIVPTFRWSDKYHGSQMQSFWLWVEDPESD-IIHYSEMISVTKKQVIEREAIEIIFAIPIFEPMPSRYLLRIVSNVWIGSDSLTDISFKNLILPELHPPHTNLLDLRPLPVSALKNEKYQQFYA--YSHFNPIQTQVFHALYYSDTNVLLGAPTGSGKTVAAELAMFRVFNTQPNKKVVYIAPLKALVRERTDDWKKKFEDILHKKVVELTGDIAPDMKAVAESDLIVTTPEKWDGVSRSWQERKFVQDVALIVIDEIHLLG-EDRGPVLEVIVSRTNFITAHTKCKVRIIGLSTALANARDLADWLQIDTNSMGLYNFRPSVRPAPLQIHIQGFSGRHYCPRMATMNKPIYQAIEIHSSEKPVLIFVSSRRQTRLTAFDLISFAVSSDKPRQWTNLSHDETEFLLQNIRDNDLKLVLSYGIGMHHAGLHEKDRKLVENLFLNQKIQILIATSTLAWGVNFPAHLVVVKGTEFFDGKTKRYVDYPITDVLQMMGRAGRPQFDNNGKAVIMVHDIKKEFYKKFLYEPFPVESSLLKVLPDHMNAEIIAGSITSKQSAMNYLTWTFFYRRLLMNPNYYSLEAVDHKAINLYLSRLIENIVYELEQSQCIETDESGTLEPGIMGRIASYYYLKHQSVRLFHSKLKSDSSLEDLLDILTSTEEFAELPVRHNENQLNAELAK--KVPIKLDANTMDSPNTKGNLLLQAYFSRVALPITDYYTDTKLVLDQAIRIVQAMIDAAGSEGWLATCLRLANVIQMLVQGLWVSDHPLLQLP 1902

HSP 2 Score: 60.077 bits (144), Expect = 2.970e-8
Identity = 27/85 (31.76%), Postives = 49/85 (57.65%), Query Frame = 1

Query: 6223 DNISSVYANNFPYKREESWWLVVGEPNQGHLISIK---LLSSPTEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV 6468
            + I   +A  FP  ++E + +++G+P    ++ +K   ++     K+S+ F +P + G   YTLY MSDSY+G DQE    ++V+
Sbjct: 2074 NKIPKAFAPKFPKPKDEGYIIILGDPENQEVLGLKRIPMIRQANTKISITFFSPEQIGRSVYTLYVMSDSYIGFDQELPIYLDVM 2158

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Planmine SMEST
Match: SMESG000005293.1 (SMESG000005293.1)

HSP 1 Score: 409.453 bits (1051), Expect = 5.978e-125
Identity = 211/281 (75.09%), Postives = 229/281 (81.49%), Query Frame = 1

Query: 1195 KEDIVTAERNRKTQARSAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGSFRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRKSSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMR 2037
            K+DIV AER RKTQ+RS K QAD+EME+SNVI NYG V+MLDLKNITFTQGSH MTNKNCELPDGS+RKTKPGYNLV VPAP PKPL+ADENLVKI+D  SYVKAAFE IKTLNRIQS+VYKTALESDENIL+CAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVY+AP+KSLVNEMA SFS+RLK YNLKV+MLSGDSHLSR+EI +  II       D I     E                     RGPVLEAIVART+RA QSSHSNID+R
Sbjct:    2 KKDIVGAERRRKTQSRSEKSQADVEMENSNVIPNYGCVNMLDLKNITFTQGSHPMTNKNCELPDGSYRKTKPGYNLVYVPAPTPKPLKADENLVKISDFQSYVKAAFENIKTLNRIQSEVYKTALESDENILICAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYVAPLKSLVNEMAKSFSDRLKRYNLKVSMLSGDSHLSRKEIIKLLII-------DEIHLLHDE---------------------RGPVLEAIVARTIRANQSSHSNIDIR 254

HSP 2 Score: 307.76 bits (787), Expect = 7.095e-90
Identity = 159/206 (77.18%), Postives = 179/206 (86.89%), Query Frame = 1

Query: 2878 RMRKNPSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNEIGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVRXXXXXXXXXXXXNVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAYISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFKK 3495
            R+RK PSLYGVEN L DDPTL+NHCR+LIYTAA+ILEKAEMINFDKRSGEF SNEIGRIAA+YYC NETM+V K+FLK++  +IE+ KVFSKC EFRNITVREEDKIEIKKL+E+V  PIKE  EDP TKINCL+QAYIS L LERFTLSSDT YI++SA RL+RAMFE TLSKK A L+  VLE CKEVE+RMW+ S PLRQFKK
Sbjct:  345 RVRKTPSLYGVENALFDDPTLENHCRSLIYTAANILEKAEMINFDKRSGEFFSNEIGRIAAHYYCANETMNVFKRFLKETTCNIEIIKVFSKCCEFRNITVREEDKIEIKKLMEHVGTPIKESVEDPSTKINCLMQAYISHLTLERFTLSSDTTYIAESATRLIRAMFEFTLSKKCAILSEMVLEICKEVEKRMWSISFPLRQFKK 550

HSP 3 Score: 59.6918 bits (143), Expect = 2.274e-8
Identity = 47/205 (22.93%), Postives = 93/205 (45.37%), Query Frame = 1

Query: 5371 RMTRNPNYYNLKGV--SHRHLSDHLSELVENTLMDLENSKCIAI-KDDIDVSAINLGMIATFYYIHYTTIEMFSLSLKPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLSDPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNRWLGPALAAMELAQMITQAQWHRDSLLKQ 5976
            R+ + P+ Y ++        L +H   L+      LE ++ I   K   +  +  +G IA  YY    T+ +F   LK  +    ++++     EF ++ +R  + + + ++ + +  PI E   + DP TK N L+QAY+S + ++   L  D   I   + RLI+A  +   S +    +   +E+ + + +  W     L+Q
Sbjct:  345 RVRKTPSLYGVENALFDDPTLENHCRSLIYTAANILEKAEMINFDKRSGEFFSNEIGRIAAHYYCANETMNVFKRFLKETTCNIEIIKVFSKCCEFRNITVREEDKIEIKKLMEHVGTPIKES--VEDPSTKINCLMQAYISHLTLERFTLSSDTTYIAESATRLIRAMFEFTLSKKCAILSEMVLEICKEVEKRMWSISFPLRQ 547

HSP 4 Score: 54.299 bits (129), Expect = 1.146e-6
Identity = 45/173 (26.01%), Postives = 71/173 (41.04%), Query Frame = 1

Query: 4075 FNAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSN---------RQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLS 4566
             N IQ++ +++   SDEN+ I APTG+GKT  A + +MR             + D + VYV  L  L       +          V  L+G++++  K I                            I+L I+D++HL+  +  G  LE I +RT   +    + I I  LS
Sbjct:  114 LNRIQSEVYKTALESDENILICAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYVAPLKSLVNEMAKSFSDRLKRYNLKVSMLSGDSHLSRKEI----------------------------IKLLIIDEIHLLHDER-GPVLEAIVARTIRANQSSHSNIDIRNLS 257

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Planmine SMEST
Match: SMESG000065396.1 (SMESG000065396.1)

HSP 1 Score: 160.999 bits (406), Expect = 1.913e-41
Identity = 120/410 (29.27%), Postives = 206/410 (50.24%), Query Frame = 1

Query: 1534 NRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRK--SSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGL-FKFDSSYRPVPMEQEYLGINERKAVKRIE---LMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLL 2745
            N++Q   +     S++++++ APTG+GKT +  + +++ +   +  + ++ +  F I+Y+AP+KSL  E   S+ E+ K +++    ++GD  +  +  N+  II  TPEK D I+RK  +    +  +  L   +   +    RG  LE ++ R    + S       R +GLSAT+ N +D  ++    ++R +  +     R V +  + L     K     +   L+N  + + + +YA    +LIF  +RK T   AK + ++   R  L     D+     V+ Q   K+    L+  +  G   HHAGL   DR  VE  F    + VL STSTL+ GVNLPAH+V+IKGT  +  +  +    + L  +QM GRAGRPQ+D   V I++T+  E    L+++
Sbjct:   81 NQLQRDSFNDVFHSNKSVIIKAPTGSGKTVIFEIAVVKCL---LENESSLER--FTIIYVAPLKSLCREKWLSWQEKFKRFDIVGIEMTGDFEMICDA-NKNHIIYTTPEKLDGITRKLDTFSINFPNVKLLCFDEIHTINDGVRGVTLEVVIIRLKYLLDSR-----TRFIGLSATIGNVDDFVKWFSNIENRCISHQMPEESRSVKLTTQVLAYPRPKGQSLFQFDNLLNHRIPDLISKYADSKPLLIFCMTRKSTFQLAKFLVDQ--TRFELKF---DQIHQLGVISQ---KISEEKLRACIIRGVGFHHAGLCQLDREIVESSFLCGALPVLCSTSTLSMGVNLPAHLVVIKGTSNFNSNIEQTYTQNKL--LQMIGRAGRPQFDNSAVAIILTSSEEEVRALNMM 469

HSP 2 Score: 128.642 bits (322), Expect = 1.249e-30
Identity = 106/403 (26.30%), Postives = 192/403 (47.64%), Query Frame = 1

Query: 4078 NAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLF----SNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKK-KKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTIL---------------KLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAI--VSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVIMCQTNKKD 5220
            N +Q   F  +++S+++V I APTGSGKTV  EIA+++      S+ +    +YV  L  L + ++  W + F       I++TG+  M   + +K HII +T E  D ++R+         N++L   D++H I     G TLEV+  R +Y+   L++  R IGLS ++ N  D  +W           N  + H+ +  E ++  +T   T++ A  +P  Q++                K + + P+++F  T K T ++A  L+     D+  F    + I  +    + IS E L   +  GVGF H  L   +R ++   F   ++ +L  + TL   +   A+LV++  T  +N    +   Y+   L+QM+GRA     D++   I+  +++++
Sbjct:   81 NQLQRDSFNDVFHSNKSVIIKAPTGSGKTVIFEIAVVKCLLENESSLERFTIIYVAPLKSLCREKWLSWQEKFKRFDIVGIEMTGDFEMICDA-NKNHIIYTTPEKLDGITRKLDTFSINFPNVKLLCFDEIHTINDGVRGVTLEVVIIRLKYL---LDSRTRFIGLSATIGNVDDFVKWFSNIE------NRCISHQ-MPEESRSVKLT---TQVLAYPRPKGQSLFQFDNLLNHRIPDLISKYADSKPLLIFCMTRKSTFQLAKFLV-----DQTRFELKFDQIHQLGVISQKISEEKLRACIIRGVGFHHAGLCQLDREIVESSFLCGALPVLCSTSTLSMGVNLPAHLVVIKGTSNFNSN--IEQTYTQNKLLQMIGRAGRPQFDNSAVAIILTSSEEE 462

[Close]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Planmine SMEST
Match: SMESG000065396.1 (SMESG000065396.1)

HSP 1 Score: 160.614 bits (405), Expect = 2.183e-41
Identity = 120/410 (29.27%), Postives = 206/410 (50.24%), Query Frame = 1

Query: 1534 NRIQSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKDDFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQIIVCTPEKWDIISRK--SSEKTYTQLVKXXXXXXXXXXXXXRGPVLEAIVARTMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGL-FKFDSSYRPVPMEQEYLGINERKAVKRIE---LMNDLVYEKVMEYAGKHQVLIFVHSRKETVNTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGFAVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQVYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSLL 2745
            N++Q   +     S++++++ APTG+GKT +  + +++ +   +  + ++ +  F I+Y+AP+KSL  E   S+ E+ K +++    ++GD  +  +  N+  II  TPEK D I+RK  +    +  +  L   +   +    RG  LE ++ R    + S       R +GLSAT+ N +D  ++    ++R +  +     R V +  + L     K     +   L+N  + + + +YA    +LIF  +RK T   AK + ++   R  L     D+     V+ Q   K+    L+  +  G   HHAGL   DR  VE  F    + VL STSTL+ GVNLPAH+V+IKGT  +  +  +    + L  +QM GRAGRPQ+D   V I++T+  E    L+++
Sbjct:   83 NQLQRDSFNDVFHSNKSVIIKAPTGSGKTVIFEIAVVKCL---LENESSLER--FTIIYVAPLKSLCREKWLSWQEKFKRFDIVGIEMTGDFEMICDA-NKNHIIYTTPEKLDGITRKLDTFSINFPNVKLLCFDEIHTINDGVRGVTLEVVIIRLKYLLDSR-----TRFIGLSATIGNVDDFVKWFSNIENRCISHQMPEESRSVKLTTQVLAYPRPKGQSLFQFDNLLNHRIPDLISKYADSKPLLIFCMTRKSTFQLAKFLVDQ--TRFELKF---DQIHQLGVISQ---KISEEKLRACIIRGVGFHHAGLCQLDREIVESSFLCGALPVLCSTSTLSMGVNLPAHLVVIKGTSNFNSNIEQTYTQNKL--LQMIGRAGRPQFDNSAVAIILTSSEEEVRALNMM 471

HSP 2 Score: 128.642 bits (322), Expect = 1.436e-30
Identity = 106/403 (26.30%), Postives = 192/403 (47.64%), Query Frame = 1

Query: 4078 NAIQTQCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLF----SNRQDARCVYVTALNDLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDVLSRRWKK-KKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLETPIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNITHNATRLAAMSKPVYQTIL---------------KLSPNSPVIVFVPTMKQTEEIAFLLMGYALSDKKNFGRASEAI--VSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLELFSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLIQMVGRANHASMDDARSVIMCQTNKKD 5220
            N +Q   F  +++S+++V I APTGSGKTV  EIA+++      S+ +    +YV  L  L + ++  W + F       I++TG+  M   + +K HII +T E  D ++R+         N++L   D++H I     G TLEV+  R +Y+   L++  R IGLS ++ N  D  +W           N  + H+ +  E ++  +T   T++ A  +P  Q++                K + + P+++F  T K T ++A  L+     D+  F    + I  +    + IS E L   +  GVGF H  L   +R ++   F   ++ +L  + TL   +   A+LV++  T  +N    +   Y+   L+QM+GRA     D++   I+  +++++
Sbjct:   83 NQLQRDSFNDVFHSNKSVIIKAPTGSGKTVIFEIAVVKCLLENESSLERFTIIYVAPLKSLCREKWLSWQEKFKRFDIVGIEMTGDFEMICDA-NKNHIIYTTPEKLDGITRKLDTFSINFPNVKLLCFDEIHTINDGVRGVTLEVVIIRLKYL---LDSRTRFIGLSATIGNVDDFVKWFSNIE------NRCISHQ-MPEESRSVKLT---TQVLAYPRPKGQSLFQFDNLLNHRIPDLISKYADSKPLLIFCMTRKSTFQLAKFLV-----DQTRFELKFDQIHQLGVISQKISEEKLRACIIRGVGFHHAGLCQLDREIVESSFLCGALPVLCSTSTLSMGVNLPAHLVVIKGTSNFNSN--IEQTYTQNKLLQMIGRAGRPQFDNSAVAIILTSSEEE 464

The following BLAST results are available for this feature:

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Human
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Celegans
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Fly
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Zebrafish
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Xenopus
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Mouse
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. UniProt/SwissProt
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. TrEMBL
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Cavefish
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Sea Lamprey
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Yeast
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Nematostella
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Medaka
BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Planmine SMEST

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SNRNP200	0.000e+0	54.41	small nuclear ribonucleoprotein U5 subunit 200 [So...	[more]
SNRNP200	2.306e-75	53.43	small nuclear ribonucleoprotein U5 subunit 200 [So...	[more]
ASCC3	0.000e+0	39.63	activating signal cointegrator 1 complex subunit 3...	[more]
HFM1	1.531e-89	31.03	helicase for meiosis 1 [Source:HGNC Symbol;Acc:HGN...	[more]
ASCC3	4.141e-74	47.30	activating signal cointegrator 1 complex subunit 3...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snrp-200	0.000e+0	49.49	Putative U5 small nuclear ribonucleoprotein 200 kD...	[more]
Y54E2A.4	0.000e+0	34.73	pep chromosome:WBcel235:II:14754622:14778149:1 gen...	[more]
Y54E2A.4	7.973e-94	32.98	pep chromosome:WBcel235:II:14768462:14778149:1 gen...	[more]
Y54E2A.4	1.589e-55	30.27	pep chromosome:WBcel235:II:14773761:14778137:1 gen...	[more]
polq-1	2.034e-25	26.21	DNA polymerase theta [Source:UniProtKB/Swiss-Prot...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
l(3)72Ab	0.000e+0	53.21	gene:FBgn0263599 transcript:FBtr0075527	[more]
obe	0.000e+0	38.32	gene:FBgn0038344 transcript:FBtr0083147	[more]
DNApol-theta	1.411e-22	27.41	gene:FBgn0002905 transcript:FBtr0082662	[more]
mus301	5.067e-20	25.96	gene:FBgn0002899 transcript:FBtr0076689	[more]
tst	5.410e-16	25.19	gene:FBgn0039117 transcript:FBtr0334895	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snrnp200	0.000e+0	54.66	small nuclear ribonucleoprotein 200 (U5) [Source:Z...	[more]
snrnp200	0.000e+0	54.66	small nuclear ribonucleoprotein 200 (U5) [Source:Z...	[more]
ascc3	0.000e+0	38.65	activating signal cointegrator 1 complex subunit 3...	[more]
ascc3	2.905e-81	48.82	activating signal cointegrator 1 complex subunit 3...	[more]
hfm1	2.417e-74	28.59	helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SNRNP200	0.000e+0	51.78	small nuclear ribonucleoprotein, U5 200kDa subunit...	[more]
gipc1	0.000e+0	37.96	GIPC PDZ domain containing family member 1 [Source...	[more]
gipc1	0.000e+0	38.04	GIPC PDZ domain containing family member 1 [Source...	[more]
gipc1	0.000e+0	37.85	GIPC PDZ domain containing family member 1 [Source...	[more]
gipc1	0.000e+0	38.10	GIPC PDZ domain containing family member 1 [Source...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Snrnp200	0.000e+0	54.31	small nuclear ribonucleoprotein 200 (U5) [Source:M...	[more]
Ascc3	0.000e+0	38.52	activating signal cointegrator 1 complex subunit 3...	[more]
Hfm1	1.271e-94	31.17	HFM1, ATP-dependent DNA helicase homolog [Source:M...	[more]
Hfm1	1.271e-94	31.17	HFM1, ATP-dependent DNA helicase homolog [Source:M...	[more]
Polq	2.922e-27	28.42	polymerase (DNA directed), theta [Source:MGI Symbo...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O75643\|U520_HUMAN	0.000e+0	54.41	U5 small nuclear ribonucleoprotein 200 kDa helicas...	[more]
sp\|Q6P4T2\|U520_MOUSE	0.000e+0	54.31	U5 small nuclear ribonucleoprotein 200 kDa helicas...	[more]
sp\|F1LNJ2\|U520_RAT	0.000e+0	54.24	U5 small nuclear ribonucleoprotein 200 kDa helicas...	[more]
sp\|Q9VUV9\|U520_DROME	0.000e+0	53.21	Putative U5 small nuclear ribonucleoprotein 200 kD...	[more]
sp\|Q9U2G0\|U520_CAEEL	0.000e+0	49.49	Putative U5 small nuclear ribonucleoprotein 200 kD...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3IYW6	0.000e+0	54.46	U5 small nuclear ribonucleoprotein 200 kDa helicas...	[more]
A0A087TVN5	0.000e+0	54.63	U5 small nuclear ribonucleoprotein helicase (Fragm...	[more]
A0A3S3P5W2	0.000e+0	54.58	Antiviral helicase Slh1-like protein OS=Dinothromb...	[more]
A0A3S1AA11	0.000e+0	53.80	Uncharacterized protein OS=Elysia chlorotica OX=18...	[more]
A0A3B3T081	0.000e+0	54.15	Small nuclear ribonucleoprotein 200 (U5) OS=Paramo...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snrnp200	0.000e+0	53.95	small nuclear ribonucleoprotein U5 subunit 200 [So...	[more]
ascc3	0.000e+0	38.62	activating signal cointegrator 1 complex subunit 3...	[more]
hfm1	1.218e-79	29.54	helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
polq	5.343e-26	28.06	DNA polymerase theta [Source:NCBI gene;Acc:1030397...	[more]
helq	4.983e-20	29.86	helicase, POLQ like [Source:ZFIN;Acc:ZDB-GENE-0605...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ascc3	9.459e-84	41.27	activating signal cointegrator 1 complex subunit 3...	[more]
ascc3	5.684e-84	41.29	activating signal cointegrator 1 complex subunit 3...	[more]
ENSPMAT00000005265.1	4.123e-120	53.80	pep scaffold:Pmarinus_7.0:GL487662:5509:13814:-1 g...	[more]
ENSPMAT00000003190.1	1.257e-51	27.50	pep scaffold:Pmarinus_7.0:GL480029:355:29241:-1 ge...	[more]
helq	3.115e-22	26.54	helicase, POLQ like [Source:ZFIN;Acc:ZDB-GENE-0605...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
BRR2	0.000e+0	38.31	RNA-dependent ATPase RNA helicase (DEIH box); requ...	[more]
SLH1	0.000e+0	35.94	Putative RNA helicase related to Ski2p; involved i...	[more]
HFM1	9.557e-75	34.39	Meiosis specific DNA helicase; involved in the con...	[more]
SKI2	1.132e-13	29.71	Ski complex component and putative RNA helicase; m...	[more]
MTR4	1.382e-12	22.95	ATP-dependent 3'-5' RNA helicase of the DExD/H fam...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO49146	0.000e+0	51.87	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46714	0.000e+0	40.15	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26736	2.883e-27	41.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34884	1.687e-23	26.76	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44748	1.817e-22	27.42	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snrnp200	0.000e+0	53.50	small nuclear ribonucleoprotein U5 subunit 200 [So...	[more]
snrnp200	0.000e+0	54.09	small nuclear ribonucleoprotein U5 subunit 200 [So...	[more]
ascc3	6.886e-65	41.96	activating signal cointegrator 1 complex subunit 3...	[more]
snrnp200	5.102e-178	58.90	small nuclear ribonucleoprotein U5 subunit 200 [So...	[more]
hfm1	5.780e-72	29.59	helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]

BLAST of U5 small nuclear ribonucleoprotein 200 kDa helicase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000004936.1	0.000e+0	99.86	SMESG000004936.1	[more]
SMESG000072466.1	2.970e-8	39.68	SMESG000072466.1	[more]
SMESG000005293.1	5.978e-125	75.09	SMESG000005293.1	[more]
SMESG000065396.1	1.913e-41	29.27	SMESG000065396.1	[more]
SMESG000065396.1	2.183e-41	29.27	SMESG000065396.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034055 ID=SMED30034055|Name=U5 small nuclear ribonucleoprotein 200 kDa helicase|organism=Schmidtea mediterranea sexual|type=transcript|length=6505bp
ATTTAACTTAAAGTTTCGATTTGAGAAAAACAAAAACTTACCATGGCTGA
TAATATAGCTCGAACGATGCAATTTGAGTACAAAATGAACTCAAATTTAG
TTTTGACAGCAGACAGAACTCTGATTGATCGTAGATCTAAGGATGAGCCC
ACCGGAGAAGTTTTACCAATTAAAGATATAGATCCAAAGAAAATGGGTGC
TCGAGTGTTAAAGCGTAAGCCTGATTGTATGGAAGAAAAACAGGATAAAC
GTATTAAAAGAGACCAATCGAATAGAACTTTAGATTATCAGAAAACTGAA
AGTGTTCTTACTTCAGATGTTATACAACAAAAGTTCAACTATGCTCCAAA
AACAGCCGAAACCAAATCAGTATACGAAGCAATGCTGAATATAGTTAATA
ATGTTCTACCAGAAGCAGATATGCATAATATAACTCAAGAAACTACTGAT
GAATTACTTATTGATTTAAAAAATTCTAATTTATCAGACAAAGAAAGAAA
GAAAGCAGCTAAAGAACTTCTTGGAAATAATTTAACGGATACTCAATATA
ATAGTCTGGTCAGTTTGTCAATTAAGCTAACTGATTATAAAGCTCCGAAA
TTTTTTACAAATGAAAATAATGACGACACAAATGATTTACATATTGAAAT
TGATGACGACCAGGAGGAAGAAGAAGATGATGTATATGGAGAAGTACAAG
ACTCAGAATCTGACGATGGAGGTGTAGAAGCCGATACAAACACGACTTTG
AACATTTCTCAATTTGCTGCTGGTACAATTTCTCAAGTTCCTGGAACAAG
CACAATTTTACCGTATTGCGGGTACCTAATACAACAAAAGAATATTGCAA
ATAGTGAAAAATTGAACGTCAATGACATAGATGCATTTTGGTTACAAAGA
ACTTTGAGTAAACATTTTACTGATCCCAATGAATGTCAAAAGCGAACTAA
AGATATTTTGGAAGTGTTAAAAATTGCTAAGAACGATCAAGAGTTAGAAA
ATAAACTACTTCGAATTGTTGGAGTCGACCGATTTGATTTGGTACGAATG
TTGAGAGAAAATAAATTAATGATTTATTACTGCACGAAATTGTGTTGTTC
TCAAACGCCTGAGGAACGAAACAAAATTGAAGCTGAAATGAAAACTGATC
CTAAATCAAATAGAATTTTAGCTGATTTGAGAAATATTGATCGAAAAGAG
GACATTGTTACTGCAGAGAGAAACCGAAAGACTCAGGCAAGGTCGGCGAA
AATTCAAGCTGATATAGAAATGGAAGATAGCAACGTAATATCTAATTATG
GAAGCGTCGATATGTTAGATTTGAAGAATATTACATTCACTCAAGGTAGT
CACCTTATGACAAATAAAAATTGTGAATTGCCTGATGGGTCATTTAGGAA
AACTAAACCTGGATATAATCTCGTTTGTGTCCCGGCACCAAAGCCAAAGC
CTTTAGAAGCGGATGAGAATCTAGTGAAAATCGCAGATTTGCCGTCATAT
GTAAAAGCTGCTTTCGAAAAAATTAAGACTCTCAATCGAATACAATCAAA
AGTTTACAAAACTGCTTTGGAAAGTGACGAAAACATTTTACTTTGTGCTC
CGACTGGGGCTGGTAAGACTAATGTAGCACTACTTACTATGATGAGGGAG
ATAGGAAAACACATAAATACAGATGGAACAATTAGAAAGGACGATTTCAA
AATTGTGTACATTGCTCCAATGAAATCGTTGGTCAATGAAATGGCCAATT
CATTTTCTGAGCGTTTGAAAAGTTATAATTTAAAAGTTGCTATGCTAAGT
GGAGATAGTCATTTAAGCAGAGAAGAAATCAATGAAACTCAGATTATCGT
ATGTACCCCTGAAAAATGGGACATTATTTCACGGAAATCGAGTGAAAAAA
CGTATACTCAATTGGTAAAACTTCTCATTATTGATGAAATCCATTTATTG
CACGACGAAAGAGGTCCAGTGTTAGAAGCAATCGTAGCTCGAACAATGCG
GGCGATGCAATCTTCGCACAGTAATATCGATATGAGAATTGTTGGATTGT
CAGCTACTCTTCCAAATACTGAGGATATCGCAGAATTTATCCACGTAGAT
AAACACAGGGGATTGTTTAAATTCGATAGCAGCTACCGTCCAGTGCCAAT
GGAACAAGAATATCTCGGCATTAATGAGCGAAAAGCCGTAAAACGGATAG
AATTGATGAATGATTTGGTATATGAAAAAGTAATGGAATATGCCGGCAAG
CATCAAGTTCTCATATTTGTACACAGCCGCAAGGAAACCGTGAATACTGC
GAAAGCAATCAAAGAAAAATGTTTAAATCGAGACACTCTTGGATTGTTTC
TTCGGGACAAGAAAGCGTCAACTCTAGTTTTACAACAGGATCTGGATAAG
GTGAAAAATCATGATCTGAAAGATTTACTGCCATACGGATTTGCTGTTCA
TCACGCCGGATTGGCCTACACCGATAGAAACTTTGTAGAGGAATTATTCA
CTGACAAACACATTCAAGTGCTCGTGTCAACTTCTACGTTAGCTTGGGGG
GTGAACTTACCGGCTCACGTTGTAATAATCAAAGGAACTCAAGTCTATAG
ACCAGATAAAGGAGAATGGACTGAACTGAGTGCCCTTGATGTCATGCAAA
TGTTCGGCAGAGCCGGTAGACCGCAATATGACACAAAAGGTGTCGGTATA
ATGATCACAAATGAGAATGAACTGACCTATTATTTGAGCTTGCTCAATGA
ACAGTTACCTATCGAGAGTCAATTGATTAGCAAATTAGCTGACAATCTCA
ATGCAGAAATAGTAATGGGAACCGTTAGAAACATTCATGAATCGATTGAC
TGGCTGCGTTACACATATCTGTACATTAGAATGCGTAAAAATCCATCTTT
GTATGGAGTTGAAAACGTGCTAATCGATGACCCAACACTTGATAATCATT
GTCGAAATTTGATTTACACAGCTGCCAGTATTCTAGAAAAGGCGGAAATG
ATAAATTTTGACAAGAGATCCGGAGAATTCATTTCAAATGAAATTGGCCG
AATCGCTGCCTATTACTATTGTACAAACGAAACGATGGATGTATTGAAAA
AGTTCCTCAAGAAATCAATGGGTGATATTGAAGTGTTTAAAGTATTTTCA
AAATGTGCCGAGTTTCGCAACATAACGGTTCGAGAAGAGGATAAAATTGA
GATTAAAAAGCTACTGGAAAATGTGCCGGTTCCGATAAAAGAAGGTGCAG
AAGATCCACCGACGAAAATCAATTGTTTACTTCAAGCGTACATTTCCCAG
TTGAAATTAGAGCGATTTACCCTATCTAGTGACACTGCATATATTTCCCA
ATCGGCTGCCCGTTTGATGCGAGCAATGTTCGAGGTTACATTGTCTAAAA
AATGGGCCAGTTTAACGTTATCAGTGCTGGAATCATGCAAAGAAGTCGAA
CAGAGAATGTGGGCCTGCTCGTGTCCTCTGAGACAATTCAAAAAGGTGCC
ATGGGAAATAACTAAAAAACTGGAAAAGAAAAACATTCCATTTGATAGAT
TAATCGATCAGAAACATCACGAATTGGGGGAATTGGTGAATAACCATAAA
ATGGGGAAAACAATTTACAAATATATTCACCAGATTCCGAAATTGAATCT
GAAAATTCATTTACAGCCAATAACGAGGAGCACTATGAAAGTCGAGTTGA
CAATTACTCCCGATTTTGAGTGGTGTCCCAAAAGCCACGGATCATCTCAG
GGATTCTGGATTTTTGTTGAGGACGTTATGTCAGAAAATATTCTACATTA
CGAATATTTCCTGTTAAAGGAAAAATTTAAAAACGATGATCATATCCTGA
AGTTCTACGTTTCAATATATGATCCATTGCCACCATTGTATTATATTCGT
GCGGTTTCCGATAAATGGATCGGATTAGAAACCGAAATTACAATAGTATT
CTTTAATGTTTTATTACCGGAGAAAAATCATCCACTAACAGAACTTCTCG
ATTTACAAAAACTTCCGTACAAAGCTTTGAGAAATGAAGAGTACGAGTCT
ATTTATTCAAAGAAAATGTCATTTTTCAACGCAATACAAACCCAGTGTTT
TGAATCGTTATACAATTCAGACGAGAATGTGTTCATTGGAGCTCCGACTG
GTAGCGGTAAAACCGTTTGTGCAGAGATTGCAATTATGCGATTATTCTCC
AATAGACAAGATGCTCGATGTGTTTATGTGACTGCTTTGAATGATTTGGC
ACAATTACGATATACTGAATGGATGAAAACATTTGGCGCCCTGGGGAAAA
CTGTTATCAAATTGACTGGAAACACAAACATGGATAATAAGAGTATTTCT
AAAGCACATATTATCGTATCGACCGCTGAGAATTGGGATGTGTTGTCTAG
GCGATGGAAAAAGAAAAAGGCTATTCAGAACATTCAATTATTTATCGTGG
ATGATCTCCATTTGATTGGTAGTCAGCATAACGGAACCACATTAGAAGTG
ATTTGCTCTAGAACTAGATATATGAGCTCGCAACTAGAAACTCCAATTAG
AATTATCGGATTGTCTTATTCATTAACCAATGCCAGAGATGTTGGCGAAT
GGTTGGATTGCCATCATACGGCAACGTACAATTTCAATCCCAGTGTCAGA
CATCGTCCTTTGGATATTGAAATCCAGACCTTCAATATCACACACAACGC
TACCCGATTGGCTGCAATGAGTAAACCGGTTTATCAAACCATATTGAAAT
TATCACCGAATAGTCCGGTAATTGTATTTGTTCCGACAATGAAGCAAACC
GAAGAAATCGCTTTCCTATTAATGGGTTACGCATTATCGGACAAGAAAAA
TTTCGGAAGAGCAAGTGAAGCAATTGTCAGTGAATATATGAGAAATATAT
CCAATGAAATTCTTATTGAGACATTGTCTTGTGGCGTTGGATTTATTCAC
GAAGCTTTATCGATCAATGAACGCAATCTCATGTTGGAGTTGTTCTCTAG
TCAATCTATTCAAATTTTGGTGGTCAGTCATACTCTTTGTTGGTCGATCC
CATCGGATGCGTATCTGGTGATTGTCATGGATACACAGGTGTACAACGGC
AAAGATTGCATGTACGACGACTATTCGGCAGTGGATTTAATTCAGATGGT
CGGTCGCGCCAATCATGCCTCAATGGACGATGCTAGATCAGTAATTATGT
GTCAAACCAATAAGAAAGACTTCATACAGAAATTTCTACATGAACCGTTG
CCATTGGAATCTCACCTTGACCACCAACTGCATGATCATTTCAATGCGGA
AATCGTTACAAAAACTATTGAAAACAAACAAGATGCGGTGGATTATTTAA
CTTGGACATTCCTGTATTATCGAATGACAAGAAATCCAAATTATTACAAT
TTGAAAGGAGTTAGTCATCGGCATTTAAGTGATCATTTGAGTGAACTTGT
CGAGAACACATTGATGGACTTGGAAAATTCGAAATGCATTGCAATTAAAG
ACGATATCGATGTTTCTGCTATAAATCTTGGAATGATTGCAACTTTTTAC
TATATCCACTATACAACGATTGAAATGTTTTCTCTCTCATTGAAACCGAA
TTCTAAGGTTCGCGTGTTGTTAGAACTAATCTGCAATGCAACCGAATTTG
AAGATTTACCATTAAGGCACGGAGAAGATGTTATTTTAACGAGAATAAAG
CAATCGTTGAGATTACCGATTTCAGAAGATCGTCGACTCAGTGATCCTAG
AACCAAGGCAAATATTTTGCTGCAAGCCTATTTATCCCGAGTTCCTATCA
AAGCTGCTGAATTGAAAGAAGATCTCAATCAAATTTTAATAAAGTCAGTT
AGATTGATACAGGCTTGTGTCGATGTTCTATCGAGCAATCGTTGGTTGGG
TCCTGCTCTTGCAGCCATGGAATTGGCGCAAATGATTACTCAAGCTCAAT
GGCACAGAGATTCATTGTTGAAACAAATTCCCCATTTTAATGAGCCTAAA
TTACTTGAACGATGTGAAGCAGCCGGTGTGAAAACCGTATTCGATTTAAT
GGAGCTTGAAGATGAACAGAAATTGGCTTTAATGAATTTTCCCGATGATA
AATTACAAGATGTTGCACGTTTCTTTCAATGCTACCCGAACATTGATTTA
ACGTATGAAGTAAGCAAAAGTGTGAGTGCTGGAGGTCAGGTTTCCGTGCA
AATACATTTGGCTAGAGATGAAGATAACATTTCTTCTGTGTACGCAAATA
ATTTTCCATACAAACGAGAAGAAAGTTGGTGGTTGGTTGTTGGTGAACCA
AATCAAGGACATTTAATATCGATAAAATTGCTCAGCTCACCAACTGAGAA
AGTATCTTTAAATTTCGATGCTCCTCGAAAATCAGGCTCCTATGAATACA
CTCTGTATTTCATGTCAGACTCCTATCTTGGTTGCGACCAGGAATATCAG
TTTACAATAAATGTTGTTTAATATTATTAGAAATAAAATTTTGATAATAA
AACAA

protein sequence of SMED30034055-orf-1

>SMED30034055-orf-1 ID=SMED30034055-orf-1|Name=SMED30034055-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2143bp
MADNIARTMQFEYKMNSNLVLTADRTLIDRRSKDEPTGEVLPIKDIDPKK
MGARVLKRKPDCMEEKQDKRIKRDQSNRTLDYQKTESVLTSDVIQQKFNY
APKTAETKSVYEAMLNIVNNVLPEADMHNITQETTDELLIDLKNSNLSDK
ERKKAAKELLGNNLTDTQYNSLVSLSIKLTDYKAPKFFTNENNDDTNDLH
IEIDDDQEEEEDDVYGEVQDSESDDGGVEADTNTTLNISQFAAGTISQVP
GTSTILPYCGYLIQQKNIANSEKLNVNDIDAFWLQRTLSKHFTDPNECQK
RTKDILEVLKIAKNDQELENKLLRIVGVDRFDLVRMLRENKLMIYYCTKL
CCSQTPEERNKIEAEMKTDPKSNRILADLRNIDRKEDIVTAERNRKTQAR
SAKIQADIEMEDSNVISNYGSVDMLDLKNITFTQGSHLMTNKNCELPDGS
FRKTKPGYNLVCVPAPKPKPLEADENLVKIADLPSYVKAAFEKIKTLNRI
QSKVYKTALESDENILLCAPTGAGKTNVALLTMMREIGKHINTDGTIRKD
DFKIVYIAPMKSLVNEMANSFSERLKSYNLKVAMLSGDSHLSREEINETQ
IIVCTPEKWDIISRKSSEKTYTQLVKLLIIDEIHLLHDERGPVLEAIVAR
TMRAMQSSHSNIDMRIVGLSATLPNTEDIAEFIHVDKHRGLFKFDSSYRP
VPMEQEYLGINERKAVKRIELMNDLVYEKVMEYAGKHQVLIFVHSRKETV
NTAKAIKEKCLNRDTLGLFLRDKKASTLVLQQDLDKVKNHDLKDLLPYGF
AVHHAGLAYTDRNFVEELFTDKHIQVLVSTSTLAWGVNLPAHVVIIKGTQ
VYRPDKGEWTELSALDVMQMFGRAGRPQYDTKGVGIMITNENELTYYLSL
LNEQLPIESQLISKLADNLNAEIVMGTVRNIHESIDWLRYTYLYIRMRKN
PSLYGVENVLIDDPTLDNHCRNLIYTAASILEKAEMINFDKRSGEFISNE
IGRIAAYYYCTNETMDVLKKFLKKSMGDIEVFKVFSKCAEFRNITVREED
KIEIKKLLENVPVPIKEGAEDPPTKINCLLQAYISQLKLERFTLSSDTAY
ISQSAARLMRAMFEVTLSKKWASLTLSVLESCKEVEQRMWACSCPLRQFK
KVPWEITKKLEKKNIPFDRLIDQKHHELGELVNNHKMGKTIYKYIHQIPK
LNLKIHLQPITRSTMKVELTITPDFEWCPKSHGSSQGFWIFVEDVMSENI
LHYEYFLLKEKFKNDDHILKFYVSIYDPLPPLYYIRAVSDKWIGLETEIT
IVFFNVLLPEKNHPLTELLDLQKLPYKALRNEEYESIYSKKMSFFNAIQT
QCFESLYNSDENVFIGAPTGSGKTVCAEIAIMRLFSNRQDARCVYVTALN
DLAQLRYTEWMKTFGALGKTVIKLTGNTNMDNKSISKAHIIVSTAENWDV
LSRRWKKKKAIQNIQLFIVDDLHLIGSQHNGTTLEVICSRTRYMSSQLET
PIRIIGLSYSLTNARDVGEWLDCHHTATYNFNPSVRHRPLDIEIQTFNIT
HNATRLAAMSKPVYQTILKLSPNSPVIVFVPTMKQTEEIAFLLMGYALSD
KKNFGRASEAIVSEYMRNISNEILIETLSCGVGFIHEALSINERNLMLEL
FSSQSIQILVVSHTLCWSIPSDAYLVIVMDTQVYNGKDCMYDDYSAVDLI
QMVGRANHASMDDARSVIMCQTNKKDFIQKFLHEPLPLESHLDHQLHDHF
NAEIVTKTIENKQDAVDYLTWTFLYYRMTRNPNYYNLKGVSHRHLSDHLS
ELVENTLMDLENSKCIAIKDDIDVSAINLGMIATFYYIHYTTIEMFSLSL
KPNSKVRVLLELICNATEFEDLPLRHGEDVILTRIKQSLRLPISEDRRLS
DPRTKANILLQAYLSRVPIKAAELKEDLNQILIKSVRLIQACVDVLSSNR
WLGPALAAMELAQMITQAQWHRDSLLKQIPHFNEPKLLERCEAAGVKTVF
DLMELEDEQKLALMNFPDDKLQDVARFFQCYPNIDLTYEVSKSVSAGGQV
SVQIHLARDEDNISSVYANNFPYKREESWWLVVGEPNQGHLISIKLLSSP
TEKVSLNFDAPRKSGSYEYTLYFMSDSYLGCDQEYQFTINVV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000101	muscle cell
PLANA:0000142	posterior region of the whole animal
PLANA:0000429	neoblast
PLANA:0002056	medial muscle cell
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR035892	C2_domain_sf
IPR041094	Brr2_helicase_PWI
IPR036390	WH_DNA-bd_sf
IPR014001	Helicase_ATP-bd
IPR001650	Helicase_C
IPR004179	Sec63-dom
IPR003593	AAA+_ATPase
IPR027417	P-loop_NTPase
IPR011545	DEAD/DEAH_box_helicase_dom
IPR000008	C2_dom
IPR011991	WHTH_DNA-bd_dom
IPR014756	Ig_E-set

Vocabulary: **molecular function**
Term	Definition
GO:0003676	nucleic acid binding
GO:0005524	ATP binding
GO:0005515	protein binding
GO:0000166	nucleotide binding
GO:0003723	RNA binding
GO:0004004	ATP-dependent RNA helicase activity
GO:0004386	helicase activity
GO:0008026	ATP-dependent helicase activity
GO:0016787	hydrolase activity
GO:0042802	identical protein binding

Vocabulary: **biological process**
Term	Definition
GO:0000354	cis assembly of pre-catalytic spliceosome
GO:0000398	mRNA splicing, via spliceosome
GO:0001649	osteoblast differentiation
GO:0006397	mRNA processing
GO:0008380	RNA splicing

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005681	spliceosomal complex
GO:0005682	U5 snRNP
GO:0016020	membrane
GO:0071013	catalytic step 2 spliceosome

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR004179	Sec63 domain	SMART	SM00973	Sec63_2	coord: 1826..2139 e-value: 1.1E-87 score: 307.2 coord: 998..1303 e-value: 4.7E-104 score: 361.7
IPR004179	Sec63 domain	PFAM	PF02889	Sec63	coord: 1827..2137 e-value: 1.2E-69 score: 234.4
IPR004179	Sec63 domain	PFAM	PF02889	Sec63	coord: 999..1301 e-value: 9.0E-79 score: 264.3
IPR003593	AAA+ ATPase domain	SMART	SM00382	AAA_5	coord: 511..695 e-value: 0.0043 score: 26.3 coord: 1359..1511 e-value: 1.2 score: 12.8
IPR001650	Helicase, C-terminal	SMART	SM00490	helicmild6	coord: 786..878 e-value: 9.0E-16 score: 68.4 coord: 1622..1710 e-value: 0.014 score: 21.5
IPR001650	Helicase, C-terminal	PFAM	PF00271	Helicase_C	coord: 770..876 e-value: 3.8E-6 score: 27.2
IPR001650	Helicase, C-terminal	PROSITE	PS51194	HELICASE_CTER	coord: 702..935 score: 12.297
IPR001650	Helicase, C-terminal	PROSITE	PS51194	HELICASE_CTER	coord: 1562..1750 score: 8.821
IPR014001	Helicase superfamily 1/2, ATP-binding domain	SMART	SM00487	ultradead3	coord: 493..706 e-value: 1.4E-30 score: 117.5 coord: 1341..1545 e-value: 1.2E-16 score: 71.3
IPR014001	Helicase superfamily 1/2, ATP-binding domain	PROSITE	PS51192	HELICASE_ATP_BIND_1	coord: 506..691 score: 22.443
IPR014001	Helicase superfamily 1/2, ATP-binding domain	PROSITE	PS51192	HELICASE_ATP_BIND_1	coord: 1354..1529 score: 18.368
None	No IPR available	GENE3D	G3DSA:1.10.3380.10		coord: 1830..1971 e-value: 1.3E-47 score: 163.4
None	No IPR available	GENE3D	G3DSA:1.10.10.2530		coord: 908..997 e-value: 4.3E-32 score: 112.0
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 489..699 e-value: 1.3E-179 score: 599.2
None	No IPR available	GENE3D	G3DSA:1.10.150.20		coord: 1972..2029 e-value: 2.8E-19 score: 70.5
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 700..901 e-value: 1.3E-179 score: 599.2
None	No IPR available	PIRSF	PIRSF039073	BRR2	coord: 1..2142 e-value: 0.0 score: 2641.8
None	No IPR available	GENE3D	G3DSA:1.10.10.2530		coord: 1740..1826 e-value: 3.1E-36 score: 125.4
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 1537..1739 e-value: 3.2E-50 score: 172.3
None	No IPR available	GENE3D	G3DSA:1.10.150.20		coord: 1142..1197 e-value: 7.7E-22 score: 79.1
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 1307..1536 e-value: 2.7E-84 score: 283.9
None	No IPR available	GENE3D	G3DSA:1.10.3380.10		coord: 999..1140 e-value: 6.6E-49 score: 167.8
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 206..227
None	No IPR available	PANTHER	PTHR24075:SF13	U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE	coord: 6..2141
None	No IPR available	PANTHER	PTHR24075	FAMILY NOT NAMED	coord: 6..2141
None	No IPR available	CDD	cd18021	DEXHc_Brr2_2	coord: 1344..1531 e-value: 3.82515E-100 score: 317.663
None	No IPR available	CDD	cd18795	SF2_C_Ski2	coord: 699..889 e-value: 6.54477E-61 score: 203.939
None	No IPR available	CDD	cd18019	DEXHc_Brr2_1	coord: 480..695 e-value: 1.17401E-122 score: 383.259
None	No IPR available	CDD	cd18795	SF2_C_Ski2	coord: 1539..1721 e-value: 8.52041E-26 score: 103.402
None	No IPR available	SUPERFAMILY	SSF158702	Sec63 N-terminal domain-like	coord: 1859..2032
None	No IPR available	SUPERFAMILY	SSF158702	Sec63 N-terminal domain-like	coord: 1026..1199
IPR011545	DEAD/DEAH box helicase domain	PFAM	PF00270	DEAD	coord: 1347..1508 e-value: 5.7E-18 score: 65.3
IPR011545	DEAD/DEAH box helicase domain	PFAM	PF00270	DEAD	coord: 499..675 e-value: 1.5E-28 score: 99.7
IPR035892	C2 domain superfamily	GENE3D	G3DSA:2.60.40.150		coord: 2032..2142 e-value: 6.2E-34 score: 118.3
IPR035892	C2 domain superfamily	GENE3D	G3DSA:2.60.40.150		coord: 1198..1306 e-value: 8.2E-39 score: 134.0
IPR041094	Brr2, N-terminal helicase PWI domain	PFAM	PF18149	Helicase_PWI	coord: 271..379 e-value: 4.7E-34 score: 116.9
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 1234..1522
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 694..906
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 439..684
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 1531..1737
IPR036390	Winged helix DNA-binding domain superfamily	SUPERFAMILY	SSF46785	"Winged helix" DNA-binding domain	coord: 906..1009
IPR036390	Winged helix DNA-binding domain superfamily	SUPERFAMILY	SSF46785	"Winged helix" DNA-binding domain	coord: 1737..1838
IPR014756	Immunoglobulin E-set	SUPERFAMILY	SSF81296	E set domains	coord: 2037..2141