Cactin, spliceosome C complex subunit

Overview
NameCactin, spliceosome C complex subunit
Smed IDSMED30034043
Length (bp)1788
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cactin, spliceosome C complex subunit (SMED30034043) t-SNE clustered cells

Violin plots show distribution of expression levels for Cactin, spliceosome C complex subunit (SMED30034043) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cactin, spliceosome C complex subunit (SMED30034043) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cactin, spliceosome C complex subunit (SMED30034043) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30034043

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30034043SMESG000026741.1 SmedASXL_011506SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30034043SMESG000026741.1 dd_Smed_v4_15273_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
zeta neoblastSMED30034043SMESG000026741.1 dd_Smed_v4_15273_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
neoblastSMED30034043SMESG000026741.1 SMED_13427_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30034043SMESG000026741.1 SMED_13427_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
Match: CACTIN (cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938])

HSP 1 Score: 324.709 bits (831), Expect = 4.808e-101
Identity = 209/575 (36.35%), Postives = 302/575 (52.52%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLKDNIKEEVNKTKPKDER---------------------------------------------------EEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
             G+T+  NPF D NL   FIW K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E + A     ++ +    T  +   ++   +  +  G   ++D+ Y+E      +  +A+ RL+E H   L+ +L KLK+EQG++S  L P LK   +      +P+D                                                     ++Y    Y P L++ HEL    +D  +   ++D ++L   R+Q    G  S + ED     A++G  +D+  F+ ++ +   ++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C DN   AI+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVADMEDLLEDIQVY-MELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
Match: CACTIN (cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938])

HSP 1 Score: 324.709 bits (831), Expect = 4.808e-101
Identity = 209/575 (36.35%), Postives = 302/575 (52.52%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLKDNIKEEVNKTKPKDER---------------------------------------------------EEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
             G+T+  NPF D NL   FIW K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E + A     ++ +    T  +   ++   +  +  G   ++D+ Y+E      +  +A+ RL+E H   L+ +L KLK+EQG++S  L P LK   +      +P+D                                                     ++Y    Y P L++ HEL    +D  +   ++D ++L   R+Q    G  S + ED     A++G  +D+  F+ ++ +   ++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C DN   AI+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVADMEDLLEDIQVY-MELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
Match: CACTIN (cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938])

HSP 1 Score: 324.709 bits (831), Expect = 4.808e-101
Identity = 209/575 (36.35%), Postives = 302/575 (52.52%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLKDNIKEEVNKTKPKDER---------------------------------------------------EEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
             G+T+  NPF D NL   FIW K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E + A     ++ +    T  +   ++   +  +  G   ++D+ Y+E      +  +A+ RL+E H   L+ +L KLK+EQG++S  L P LK   +      +P+D                                                     ++Y    Y P L++ HEL    +D  +   ++D ++L   R+Q    G  S + ED     A++G  +D+  F+ ++ +   ++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C DN   AI+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVADMEDLLEDIQVY-MELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
Match: CACTIN (cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938])

HSP 1 Score: 324.709 bits (831), Expect = 4.808e-101
Identity = 209/575 (36.35%), Postives = 302/575 (52.52%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLKDNIKEEVNKTKPKDER---------------------------------------------------EEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
             G+T+  NPF D NL   FIW K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E + A     ++ +    T  +   ++   +  +  G   ++D+ Y+E      +  +A+ RL+E H   L+ +L KLK+EQG++S  L P LK   +      +P+D                                                     ++Y    Y P L++ HEL    +D  +   ++D ++L   R+Q    G  S + ED     A++G  +D+  F+ ++ +   ++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C DN   AI+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVADMEDLLEDIQVY-MELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
Match: CACTIN (cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938])

HSP 1 Score: 240.35 bits (612), Expect = 3.195e-74
Identity = 111/210 (52.86%), Postives = 145/210 (69.05%), Query Frame = 3 
Query: 1122 EEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            ++Y    Y P L++ HEL    +D  +   ++D ++L   R+Q    G  S + ED     A++G  +D+  F+ ++ +   ++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C DN   AI+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:   85 DDYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 291
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
Match: cacn-1 (Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14])

HSP 1 Score: 205.682 bits (522), Expect = 1.122e-62
Identity = 95/154 (61.69%), Postives = 116/154 (75.32%), Query Frame = 3 
Query: 1290 QLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            +++ +A++G E D+  F  +  +     LWSDKYRPRKP +LNRV TGFDWNKYNQTHYD DNPPPKIVQGYKFNI YPDL+D +  P F L+ C D D  AII FKAGPPY+DIAFK+VN+EWET  + GYKCQF   + Q+ F FK+YRYR+
Sbjct:   44 KMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPD-FAIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR 196
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
Match: cacn-1 (Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14])

HSP 1 Score: 208.764 bits (530), Expect = 5.382e-62
Identity = 108/216 (50.00%), Postives = 134/216 (62.04%), Query Frame = 3 
Query: 1119 REEYIYKLYEPVLISEHEL--GEEVIDY---VIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            RE Y    Y P  IS  +   G E++D    V    E   R   ++                +++ +A++G E D+  F  +  +     LWSDKYRPRKP +LNRV TGFDWNKYNQTHYD DNPPPKIVQGYKFNI YPDL+D +  P F L+ C D D  AII FKAGPPY+DIAFK+VN+EWET  + GYKCQF   + Q+ F FK+YRYR+
Sbjct:  131 RELYRIGCYSPTYISADDTMPGIEILDEQADVDNLTERRNRNRGTLPSSSAASSGAPQGASSKMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPD-FAIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR 345
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
Match: cacn-1 (Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14])

HSP 1 Score: 212.616 bits (540), Expect = 2.022e-60
Identity = 95/154 (61.69%), Postives = 116/154 (75.32%), Query Frame = 3 
Query: 1290 QLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            +++ +A++G E D+  F  +  +     LWSDKYRPRKP +LNRV TGFDWNKYNQTHYD DNPPPKIVQGYKFNI YPDL+D +  P F L+ C D D  AII FKAGPPY+DIAFK+VN+EWET  + GYKCQF   + Q+ F FK+YRYR+
Sbjct:  505 KMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPDF-AIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR 657

HSP 2 Score: 69.707 bits (169), Expect = 3.221e-12
Identity = 74/281 (26.33%), Postives = 130/281 (46.26%), Query Frame = 3 
Query:  252 FTDDVNPFMDPNLTEQFIWKKNKRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNYLGRKND-----------STFDLDQAIVRSKIRINSDRGQPIDYLIQYI---NEENECSTDTNVIMNEPTQYLLMLDKQ--QLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTENGRDEALSKESIEAMKDMVLSGTIGEAIELYN--DSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQ 1040
            +T+  NPF D  LT+ F+W K   +      T++   ++  +R+R++     E +  ++    AKE    + R  D             F +DQ   R++IRI+  R + ID L +Y    +E    +   +  +  P +YL    K      +L+ DI  Y       KN  +W D   I EDE+ K      G   A  +  ++   +M  + +I E ++L +  D+K    +G++      Y++   +  K+ IA++RL+E+H R L++QL  +KEEQ
Sbjct:   90 YTNLNNPFNDTKLTQTFVWGKKLEREGKSGLTQDEITKQTSQRIRKNLHEAAEFKRIRDSRAAAKEDMEMMKRDADLRAGQISDTKEREFQMDQIKERTRIRIDQGRAKAIDLLSRYARFADENPHTAKIPDFELENPMEYLKASCKSVDDYEDLIEDIKTYREVDGWAKNETWWMDVTRIAEDEIQKKAAQNRGDVHASVQTEVQ---NMFKNKSIDELLKLEDQMDAKIRGNSGNK-----GYWQDLDDQLKVFIARKRLREHHGRVLRLQLAIIKEEQ 362
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
Match: cacn-1 (Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14])

HSP 1 Score: 212.616 bits (540), Expect = 2.022e-60
Identity = 95/154 (61.69%), Postives = 116/154 (75.32%), Query Frame = 3 
Query: 1290 QLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            +++ +A++G E D+  F  +  +     LWSDKYRPRKP +LNRV TGFDWNKYNQTHYD DNPPPKIVQGYKFNI YPDL+D +  P F L+ C D D  AII FKAGPPY+DIAFK+VN+EWET  + GYKCQF   + Q+ F FK+YRYR+
Sbjct:  505 KMMAIAREGMEADESIFGAEEQLAAQRHLWSDKYRPRKPTYLNRVQTGFDWNKYNQTHYDQDNPPPKIVQGYKFNIFYPDLLDMTVAPRFGLTSCEDPDF-AIIRFKAGPPYEDIAFKVVNREWETLHKNGYKCQFQNGVFQLWFMFKKYRYRR 657

HSP 2 Score: 69.707 bits (169), Expect = 3.221e-12
Identity = 74/281 (26.33%), Postives = 130/281 (46.26%), Query Frame = 3 
Query:  252 FTDDVNPFMDPNLTEQFIWKKNKRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNYLGRKND-----------STFDLDQAIVRSKIRINSDRGQPIDYLIQYI---NEENECSTDTNVIMNEPTQYLLMLDKQ--QLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTENGRDEALSKESIEAMKDMVLSGTIGEAIELYN--DSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQ 1040
            +T+  NPF D  LT+ F+W K   +      T++   ++  +R+R++     E +  ++    AKE    + R  D             F +DQ   R++IRI+  R + ID L +Y    +E    +   +  +  P +YL    K      +L+ DI  Y       KN  +W D   I EDE+ K      G   A  +  ++   +M  + +I E ++L +  D+K    +G++      Y++   +  K+ IA++RL+E+H R L++QL  +KEEQ
Sbjct:   90 YTNLNNPFNDTKLTQTFVWGKKLEREGKSGLTQDEITKQTSQRIRKNLHEAAEFKRIRDSRAAAKEDMEMMKRDADLRAGQISDTKEREFQMDQIKERTRIRIDQGRAKAIDLLSRYARFADENPHTAKIPDFELENPMEYLKASCKSVDDYEDLIEDIKTYREVDGWAKNETWWMDVTRIAEDEIQKKAAQNRGDVHASVQTEVQ---NMFKNKSIDELLKLEDQMDAKIRGNSGNK-----GYWQDLDDQLKVFIARKRLREHHGRVLRLQLAIIKEEQ 362
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Fly
Match: cactin (gene:FBgn0031114 transcript:FBtr0340400)

HSP 1 Score: 300.442 bits (768), Expect = 1.464e-92
Identity = 207/560 (36.96%), Postives = 307/560 (54.82%), Query Frame = 3 
Query:  252 FTDDVNPFMDPNLTEQFIWKKNKRQIK----MDCQTKEA-----------ELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNYLG-RKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDT-NVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE------NGRDEALSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEE---QGLDSSSLPTLKDNIKE-------EVNKTKPKDEREE----------YIYKLYEPVLISEHE----------LGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLL-------AQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            ++++ NPF D NLT  F W K K +++    +  +T E            ELEKV+KR +E E  R+ R+ +  + QRAKE+  +   ++ +  F L+QA +RS+IRI   R +PID L QY+   NE   +   + M+EP   L  L  ++L +LLVDI  Y   +  GK+  +W D   IV+DEL +  + E      N R + + +  ++ + D +  G   + +E      +   +G    +DISY+E   +  K  +A+ RL++ H   L+ +L  LK E   + L     P +K+   E       EV +  P+DE +           Y    Y P  I E +          + E   + ++Y  EDDER+    ++Q L   H      +QL          A++G + D+  F+ +  ++    L +DKYRPRKPR+ NRV+TGF+WNKYNQTHYD+DNPPPKIVQGYKFNI YPDL+DKS+TP + L+ C DN   A++ F  GPPY+DIAFKIVN+EWE S + G++CQF+ N+ Q+ FHFKRYRYR+
Sbjct:  167 YSNEDNPFGDSNLTSTFHWGK-KLEVEGLSNLSTKTVEVLSLQKQLENRRELEKVKKRRQERELERQVREDDLMMQQRAKEAVQFREWQRQEDQFHLEQARLRSEIRIRDGRAKPIDLLAQYVAAGNEPLEECLEMQMHEPYVLLNGLPVEELEDLLVDIKVYE-ELEQGKHIDFWNDMITIVQDELQRQQKLEAENSSLNQRRDGIHQAVVKDVAD-IFRGKNAQQLEEMRHRIEAKISGRADGVDISYWESLLSQLKAHMARARLRDRHQALLREKLSLLKRENDNETLQEKVAPQVKEEEMETQDAEDPEVEEGSPEDEEDPLNELRKTVRLYQAGNYSPRYIREEDFTGRRAQNEDVDEPEAEGLLYEEEDDERR---TQRQRLLILHPERVDNNQLTPQELRMRNEAKQGMQGDEAEFSVETTLDAVPQLATDKYRPRKPRYFNRVHTGFEWNKYNQTHYDMDNPPPKIVQGYKFNIFYPDLMDKSQTPQYFLTPCADNGDFAVLRFHTGPPYEDIAFKIVNREWEFSYKRGFRCQFHNNIFQLWFHFKRYRYRR 720
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Zebrafish
Match: cactin (cactin [Source:NCBI gene;Acc:100126813])

HSP 1 Score: 246.899 bits (629), Expect = 1.670e-71
Identity = 113/209 (54.07%), Postives = 142/209 (67.94%), Query Frame = 3 
Query: 1125 EYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            EY    Y P L+   EL    +D  I   E+D ++L+  R+Q    G  S + ED  +  A++G   D+  F+ ++ +    +LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  CPDN    I+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  630 EYDSGRYSPTLLQNSEL---PLDTHIIAEEEDLQRLLLARRQMQVTGDASESAEDLFVRRAKEGMGGDEAQFSVEMPLTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPCPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 835

HSP 2 Score: 115.161 bits (287), Expect = 2.842e-26
Identity = 102/309 (33.01%), Postives = 161/309 (52.10%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIKEEVNKTKP 1109
             G+T+  NPF D NL   FIW+K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D +V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E I       ++ +    T  +   LY + +  ++ G   ++DI Y+E      ++ +A+ RL+E H   L+ +L KLK+EQG++S  L  +   IKEE  K +P
Sbjct:  252 MGYTNADNPFGDNNLLGTFIWQKALEKKGIGHLSEKNLKDRNKHIQEENRRELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWAEQEDNFHLHQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLSVEMHEPYTFLNGLTVTDMEDLLEDIKVY-MELECGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALYMNIESKIQAGGS-NLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPI---IKEEPEKEQP 552
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Zebrafish
Match: cactin (cactin [Source:NCBI gene;Acc:100126813])

HSP 1 Score: 64.3142 bits (155), Expect = 1.670e-11
Identity = 49/155 (31.61%), Postives = 80/155 (51.61%), Query Frame = 3 
Query:  663 NLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIKEEVNKTKP 1109
            +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E I       ++ +    T  +   LY + +  ++ G   ++DI Y+E      ++ +A+ RL+E H   L+ +L KLK+EQG++S  L  +   IKEE  K +P
Sbjct:    3 DLLEDIKVY-MELECGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALYMNIESKIQAGGS-NLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPI---IKEEPEKEQP 152
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Xenopus
Match: CACTIN (cactin, spliceosome C complex subunit [Source:NCBI gene;Acc:100487223])

HSP 1 Score: 329.331 bits (843), Expect = 1.853e-102
Identity = 214/569 (37.61%), Postives = 309/569 (54.31%), Query Frame = 3 
Query:  249 GFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL----------PTLKDNIKEEVNKTKP------------------KDERE-----------------EYIYKLYEPVLISEHELG--EEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            G+T+  NPF D NL   FIW K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    L +LL DI  Y   +  GKN  +W D  +I EDE+ KL + E +G+     +E + A     ++ +    T  +   +    +  + TG   ++DI Y+E      +  +A+ RL+E H   L+ +L KLK+EQG++S  L          P+ +++  E ++   P                  K+E E                 +Y    Y P L++  EL     V+D+     E+D+++ +  R+Q    G  S + ED  +  A++G + D+  F+ ++ V   ++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C DN   AI+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  239 GYTNTDNPFGDNNLLGTFIWNKALEKKGIGHLTEKDLKERNKHIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVSDLEDLLEDIQIY-MELEQGKNVDFWRDMTVITEDEISKLRKLEFSGKGPGERREGVNASVSTDVQTVFKGKTYNQLQAISQGIESRIRTGGP-NLDIGYWESLLQQLRAYMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPIIKPEPESPSNRESEVEPLSGQPPSSTSAAPEESESAIEGEEKNEAEGGESVLMEEDLIQQSLNDYDAGRYSPKLLTVQELPFDAHVVDF-----EEDQQRTVLCRQQLQVTGDASESPEDIFIRKAKEGMDGDEAQFSVEIPVTSKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACHDNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFSNGIFQLWFHFKRYRYRR 797
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Mouse
Match: Cactin (cactin, spliceosome C complex subunit [Source:MGI Symbol;Acc:MGI:1917562])

HSP 1 Score: 320.857 bits (821), Expect = 1.481e-99
Identity = 208/567 (36.68%), Postives = 301/567 (53.09%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLKDNIKE---------------EVNKTKPKDERE----------------------------EYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
             G+T+  NPF D NL   FIW K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + + +F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E + A     ++ +    T  +   ++   +  +  G   ++D+ Y+E      +  +A+ RL+E H   L+ +L KLK+EQG++S  L P LK                     V+  +P +  E                            +Y    Y P L++ HEL    +D  +    +D ++L   R+Q    G  S + ED     A++G  +D+  F+ ++ +   ++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLI K  TP + L  C DN   AI+ F AGPPY+DIAFKIV++EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  214 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELELLQREKEAEHFKTWEEQEDSFHLRQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVADMEDLLEDIQVY-MELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPILKSEPSAAHSPEPEERPPSPGTSVDPVEPVEPEEATAPGEAEGEAEGEAVLMEEDLIQQSLADYDAGRYSPRLLTAHEL---PLDAHVLEPHEDLQRLQLSRQQLQATGDASESAEDIFFRRAREGMGQDEAQFSVEMPLGGRAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIRKRATPEYFLEACADNRDFAILRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 772
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Mouse
Match: Cactin (cactin, spliceosome C complex subunit [Source:MGI Symbol;Acc:MGI:1917562])

HSP 1 Score: 84.7297 bits (208), Expect = 3.819e-18
Identity = 63/194 (32.47%), Postives = 101/194 (52.06%), Query Frame = 3 
Query:  513 SKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLK 1073
            SKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E + A     ++ +    T  +   ++   +  +  G   ++D+ Y+E      +  +A+ RL+E H   L+ +L KLK+EQG++S  L P LK
Sbjct:    4 SKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVADMEDLLEDIQVY-MELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPILK 192
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|Q8WUQ7|CATIN_HUMAN (Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3)

HSP 1 Score: 324.709 bits (831), Expect = 2.309e-100
Identity = 209/575 (36.35%), Postives = 302/575 (52.52%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLKDNIKEEVNKTKPKDER---------------------------------------------------EEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
             G+T+  NPF D NL   FIW K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E + A     ++ +    T  +   ++   +  +  G   ++D+ Y+E      +  +A+ RL+E H   L+ +L KLK+EQG++S  L P LK   +      +P+D                                                     ++Y    Y P L++ HEL    +D  +   ++D ++L   R+Q    G  S + ED     A++G  +D+  F+ ++ +   ++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  C DN   AI+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  192 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVADMEDLLEDIQVY-MELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHEL---PLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 758
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|Q9CS00|CATIN_MOUSE (Cactin OS=Mus musculus OX=10090 GN=Cactin PE=1 SV=2)

HSP 1 Score: 320.857 bits (821), Expect = 1.036e-98
Identity = 208/567 (36.68%), Postives = 301/567 (53.09%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLKDNIKE---------------EVNKTKPKDERE----------------------------EYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
             G+T+  NPF D NL   FIW K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + + +F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E + A     ++ +    T  +   ++   +  +  G   ++D+ Y+E      +  +A+ RL+E H   L+ +L KLK+EQG++S  L P LK                     V+  +P +  E                            +Y    Y P L++ HEL    +D  +    +D ++L   R+Q    G  S + ED     A++G  +D+  F+ ++ +   ++LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLI K  TP + L  C DN   AI+ F AGPPY+DIAFKIV++EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  214 MGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELELLQREKEAEHFKTWEEQEDSFHLRQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVADMEDLLEDIQVY-MELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGP-NLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPILKSEPSAAHSPEPEERPPSPGTSVDPVEPVEPEEATAPGEAEGEAEGEAVLMEEDLIQQSLADYDAGRYSPRLLTAHEL---PLDAHVLEPHEDLQRLQLSRQQLQATGDASESAEDIFFRRAREGMGQDEAQFSVEMPLGGRAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIRKRATPEYFLEACADNRDFAILRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 772
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|Q9VR99|CATIN_DROME (Cactin OS=Drosophila melanogaster OX=7227 GN=cactin PE=1 SV=3)

HSP 1 Score: 300.442 bits (768), Expect = 1.468e-91
Identity = 207/560 (36.96%), Postives = 307/560 (54.82%), Query Frame = 3 
Query:  252 FTDDVNPFMDPNLTEQFIWKKNKRQIK----MDCQTKEA-----------ELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNYLG-RKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDT-NVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE------NGRDEALSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEE---QGLDSSSLPTLKDNIKE-------EVNKTKPKDEREE----------YIYKLYEPVLISEHE----------LGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLL-------AQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            ++++ NPF D NLT  F W K K +++    +  +T E            ELEKV+KR +E E  R+ R+ +  + QRAKE+  +   ++ +  F L+QA +RS+IRI   R +PID L QY+   NE   +   + M+EP   L  L  ++L +LLVDI  Y   +  GK+  +W D   IV+DEL +  + E      N R + + +  ++ + D +  G   + +E      +   +G    +DISY+E   +  K  +A+ RL++ H   L+ +L  LK E   + L     P +K+   E       EV +  P+DE +           Y    Y P  I E +          + E   + ++Y  EDDER+    ++Q L   H      +QL          A++G + D+  F+ +  ++    L +DKYRPRKPR+ NRV+TGF+WNKYNQTHYD+DNPPPKIVQGYKFNI YPDL+DKS+TP + L+ C DN   A++ F  GPPY+DIAFKIVN+EWE S + G++CQF+ N+ Q+ FHFKRYRYR+
Sbjct:  167 YSNEDNPFGDSNLTSTFHWGK-KLEVEGLSNLSTKTVEVLSLQKQLENRRELEKVKKRRQERELERQVREDDLMMQQRAKEAVQFREWQRQEDQFHLEQARLRSEIRIRDGRAKPIDLLAQYVAAGNEPLEECLEMQMHEPYVLLNGLPVEELEDLLVDIKVYE-ELEQGKHIDFWNDMITIVQDELQRQQKLEAENSSLNQRRDGIHQAVVKDVAD-IFRGKNAQQLEEMRHRIEAKISGRADGVDISYWESLLSQLKAHMARARLRDRHQALLREKLSLLKRENDNETLQEKVAPQVKEEEMETQDAEDPEVEEGSPEDEEDPLNELRKTVRLYQAGNYSPRYIREEDFTGRRAQNEDVDEPEAEGLLYEEEDDERR---TQRQRLLILHPERVDNNQLTPQELRMRNEAKQGMQGDEAEFSVETTLDAVPQLATDKYRPRKPRYFNRVHTGFEWNKYNQTHYDMDNPPPKIVQGYKFNIFYPDLMDKSQTPQYFLTPCADNGDFAVLRFHTGPPYEDIAFKIVNREWEFSYKRGFRCQFHNNIFQLWFHFKRYRYRR 720
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|F1Q8W0|CATIN_DANRE (Cactin OS=Danio rerio OX=7955 GN=cactin PE=2 SV=1)

HSP 1 Score: 246.899 bits (629), Expect = 1.261e-70
Identity = 113/209 (54.07%), Postives = 142/209 (67.94%), Query Frame = 3 
Query: 1125 EYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            EY    Y P L+   EL    +D  I   E+D ++L+  R+Q    G  S + ED  +  A++G   D+  F+ ++ +    +LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  CPDN    I+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  630 EYDSGRYSPTLLQNSEL---PLDTHIIAEEEDLQRLLLARRQMQVTGDASESAEDLFVRRAKEGMGGDEAQFSVEMPLTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPCPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 835

HSP 2 Score: 115.161 bits (287), Expect = 2.145e-25
Identity = 102/309 (33.01%), Postives = 161/309 (52.10%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIKEEVNKTKP 1109
             G+T+  NPF D NL   FIW+K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D +V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E I       ++ +    T  +   LY + +  ++ G   ++DI Y+E      ++ +A+ RL+E H   L+ +L KLK+EQG++S  L  +   IKEE  K +P
Sbjct:  252 MGYTNADNPFGDNNLLGTFIWQKALEKKGIGHLSEKNLKDRNKHIQEENRRELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWAEQEDNFHLHQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLSVEMHEPYTFLNGLTVTDMEDLLEDIKVY-MELECGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALYMNIESKIQAGGS-NLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPI---IKEEPEKEQP 552
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Match: sp|F4I2J8|CATIN_ARATH (Cactin OS=Arabidopsis thaliana OX=3702 GN=CTN PE=1 SV=1)

HSP 1 Score: 229.565 bits (584), Expect = 4.656e-65
Identity = 189/623 (30.34%), Postives = 301/623 (48.31%), Query Frame = 3 
Query:  228 IRKKDICGFTDDVNPFMDPNLTEQFIWKKN-----KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNYLGR-----------KNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQ-QLG---NLLVDIDNY----------SCNMVPGK---------------------------------NTQYWADFKIIVEDELFKLN----------RTENGRDEALSKE-----SIEAMKDMVLSG-TIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKE-EQGLD----SSSLPTLKDNIKEEVNKTKPKDEREEY----------------IYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFL----------TFGHLSSTKEDQLLLLAQKGD---EKDDVNF--NDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            ++ + + G+++D NPF D NLTE F+W+K       R + ++  + +AE  + ++RM E E++++ R+       R +E    L R           K +  F  DQ+ VRS+IR+   R +PID L ++++     S D ++ ++EP  Y++   K+ ++G   N  + I N           +C ++  +                                   QYW    ++ + EL +            R E    E L++E      +EA    +L G T  E +EL  D +  L +G  + ++  Y+E      +I  AK  L+E H   L+  L +L++  +G D    +  L  + +  +EE+N T   D  E +                    + P L+   +  EE ID       ++++KL+ M++  +                +  ED L L A K     E+ D  F  N +V ++   + W DKYRPRKP++ NRV+TG++WNKYNQTHYD DNPPPKIVQGYKFNI YPDL+DK K P + +     + +  +I F AGPPY+DIAF+IVNKEWE S + G+KC F   +L ++F+FKR+RYR+
Sbjct:  109 LKTQSVSGYSNDSNPFGDSNLTETFVWRKKIEKDVHRGVPLEEFSVKAEKRRHRERMTEVEKVKKRREERAVEKARHEEEMALLARERARAEFHDWEKKEEEFHFDQSKVRSEIRLREGRLKPIDVLCKHLD----GSDDLDIELSEP--YMVFKKKKVRIGIWLNFQLSITNVYVEAEYKNDSACLLLRSRVDILLNKGLTVKDMEELRDDIKMYLDLDRATPTRVQYWEALIVVCDWELAEARKRDALDRARVRGEEPPAELLAQERGLHAGVEADVRKLLDGKTHAELVELQLDIESQLRSGSAKVVE--YWEAVLKRLEIYKAKACLKEIHAEMLRRHLHRLEQLSEGEDDVEVNPGLTRVVEENEEEINDTNLSDAEEAFSPEPVAEEEEADEAAEAAGSFSPELMHGDDR-EEAID------PEEDKKLLQMKRMIVLEKQKKRLKEAMDSKPAPVEDNLELKAMKAMGAMEEGDAIFGSNAEVNLDSEVYWWHDKYRPRKPKYFNRVHTGYEWNKYNQTHYDHDNPPPKIVQGYKFNIFYPDLVDKIKAPIYTIEKDGTSAETCMIRFHAGPPYEDIAFRIVNKEWEYSHKKGFKCTFERGILHLYFNFKRHRYRR 716
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: G7Y8W8 (Uncharacterized protein OS=Clonorchis sinensis OX=79923 GN=CLF_103019 PE=4 SV=1)

HSP 1 Score: 362.459 bits (929), Expect = 3.237e-111
Identity = 232/595 (38.99%), Postives = 338/595 (56.81%), Query Frame = 3 
Query:  237 KDICGFTDDVNPFMDPNLTEQFIWKK----------NKRQI----KMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY--LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENE----CSTDTNVI-MNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTEN--------------GRDEA-LSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGL-----------------------DSSSLPT-----LKDNIKEEVNKTKPK-----------------------DEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKG-DEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQE--AIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            K+  G+T++ NPF D  L+E F+WK+          +K +I    K   +  + ELE V++R  E ER REER+ E E++QR KE++ Y   G++ D TF L+QA +RS+IRI   R +PID L +YI ++ E     +  T VI + EPTQ+L+ L  + L +LLVDI      +  G+N +YW D   + EDEL KL R EN              GR  A +S+  ++++ + +   T  +   L    +  L+ G+   +D++Y+E    F +  +A+ RL++ H  NL+ +L+ L++ QG+                       D+  +P      L+    +E   T+P+                        E E Y    Y P  +   E+    +D VIY  EDD  K+   RK+ L  G + +++E++L+  A++G ++ +D  F+ Q+ +ED SFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFN+ YPDLIDKSKTPT+ L+ C D  Q   AI+ F AGPPY+DIAFKIVN+EWE S + G++CQF  N+ Q+ FHFKR+RYR+
Sbjct:  269 KEYLGYTNEDNPFGDHRLSESFVWKQKLEAEGLTHLSKEEIQELQKKKMEENKLELESVRRRRAEREREREEREKEMEMMQRDKEAEYYRSWGQQED-TFHLEQAKLRSRIRIADGRAKPIDLLAKYIADQEEDAMASAEFTGVIELLEPTQFLVGLSVEDLEDLLVDIKVVYMQLEKGRNAEYWRDITTVAEDELNKLRRAENDSAGLAAAYGADSRGRSSASISQSVMQSVAETLKGKTYNQLAALERQIEPKLKGGE--GVDVTYWETLAQFVRAQMARTRLRDMHQENLRRKLECLRQSQGIVQEPLFPSGTDQPQPSTSQMIRSDTQLMPPPAVDKLRGEEPDEPEDTQPQIEDPHSAEAIRAARQAQLEAAAMVEEEMYDAACYSPPRVDPTEVA---LDAVIYNPEDDRAKIDYQRKEVLRTGAMRASEEEELMRRAREGMEDGEDAQFSVQIPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNVFYPDLIDKSKTPTYTLTPCEDPSQRDFAILRFSAGPPYEDIAFKIVNREWEYSYKHGFRCQFQNNIFQLWFHFKRFRYRR 857
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: A0A4S2LMZ6 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006385 PE=4 SV=1)

HSP 1 Score: 359.762 bits (922), Expect = 3.294e-111
Identity = 232/595 (38.99%), Postives = 336/595 (56.47%), Query Frame = 3 
Query:  237 KDICGFTDDVNPFMDPNLTEQFIWKK----------NKRQI----KMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY--LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENE----CSTDTNVI-MNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTEN--------------GRDEA-LSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGL-----------------------DSSSLPT-----LKDNIKEEVNKTKPK-----------------------DEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKG-DEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQE--AIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            K+  G+T++ NPF D  L+E F+WK+          +K +I    K   +  + ELE V++R  E ER REER+ E E++QR KE++ Y   G++ D TF L+QA +RS+IRI   R +PID L +YI ++ E     +  T VI + EPTQ+L+ L  + L +LL DI      +  G+N +YW D   + EDEL KL R EN              GR  A +S+  ++++ + +   T  +   L    +  L+ G+   +D++Y+E    F +  +A+ RL++ H  NL+ +L+ L++ QG+                       D+  +P      L+    EE   T+P+                        E E Y    Y P  +   E+    +D VIY  EDD  K+   RK  L  G + +++E++L+  A++G ++ +D  F+ Q+ +ED SFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFN+ YPDLIDKSKTPT+ L+ C D  Q   AI+ F AGPPY+DIAFKIVN+EWE S + G++CQF  N+ Q+ FHFKR+RYR+
Sbjct:  178 KEYLGYTNEDNPFGDHRLSESFVWKQKLEAEGLTHLSKEEIQELQKKKMEENKLELESVRRRRAEREREREEREKEMEMMQRDKEAEYYRSWGQQED-TFHLEQAKLRSRIRIADGRAKPIDLLAKYIADQEEDAMASAEFTGVIELLEPTQFLVGLSVEDLEDLLEDIKVVYMQLEKGRNAEYWRDITTVAEDELNKLRRAENDSAGLAAAYGADSRGRSSASISQSVMQSVAETLKGKTYNQLAALERQIEPKLKGGE--GVDVTYWETLAQFVRAQMARTRLRDMHQENLRRKLECLRQSQGIVQEPLFPSGTDQPQPSTSQMVRSDTQLMPPPAIDKLRGEEPEEPEDTQPQIEDPHSAEAIRAARQAQLEAAAMVEEEMYDAACYSPPRVDPTEVA---LDAVIYNPEDDRAKIDYQRKDVLRTGAMRASEEEELMRRAREGMEDGEDAQFSVQIPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNVFYPDLIDKSKTPTYTLTPCEDPSQRDFAILRFSAGPPYEDIAFKIVNREWEYSYKHGFRCQFQNNIFQLWFHFKRFRYRR 766
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: A0A3R7ETC6 (Cactin OS=Clonorchis sinensis OX=79923 GN=CACTIN PE=4 SV=1)

HSP 1 Score: 362.844 bits (930), Expect = 1.068e-110
Identity = 232/595 (38.99%), Postives = 338/595 (56.81%), Query Frame = 3 
Query:  237 KDICGFTDDVNPFMDPNLTEQFIWKK----------NKRQI----KMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY--LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENE----CSTDTNVI-MNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTEN--------------GRDEA-LSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGL-----------------------DSSSLPT-----LKDNIKEEVNKTKPK-----------------------DEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKG-DEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQE--AIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            K+  G+T++ NPF D  L+E F+WK+          +K +I    K   +  + ELE V++R  E ER REER+ E E++QR KE++ Y   G++ D TF L+QA +RS+IRI   R +PID L +YI ++ E     +  T VI + EPTQ+L+ L  + L +LLVDI      +  G+N +YW D   + EDEL KL R EN              GR  A +S+  ++++ + +   T  +   L    +  L+ G+   +D++Y+E    F +  +A+ RL++ H  NL+ +L+ L++ QG+                       D+  +P      L+    +E   T+P+                        E E Y    Y P  +   E+    +D VIY  EDD  K+   RK+ L  G + +++E++L+  A++G ++ +D  F+ Q+ +ED SFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFN+ YPDLIDKSKTPT+ L+ C D  Q   AI+ F AGPPY+DIAFKIVN+EWE S + G++CQF  N+ Q+ FHFKR+RYR+
Sbjct:  347 KEYLGYTNEDNPFGDHRLSESFVWKQKLEAEGLTHLSKEEIQELQKKKMEENKLELESVRRRRAEREREREEREKEMEMMQRDKEAEYYRSWGQQED-TFHLEQAKLRSRIRIADGRAKPIDLLAKYIADQEEDAMASAEFTGVIELLEPTQFLVGLSVEDLEDLLVDIKVVYMQLEKGRNAEYWRDITTVAEDELNKLRRAENDSAGLAAAYGADSRGRSSASISQSVMQSVAETLKGKTYNQLAALERQIEPKLKGGE--GVDVTYWETLAQFVRAQMARTRLRDMHQENLRRKLECLRQSQGIVQEPLFPSGTDQPQPSTSQMIRSDTQLMPPPAVDKLRGEEPDEPEDTQPQIEDPHSAEAIRAARQAQLEAAAMVEEEMYDAACYSPPRVDATEVA---LDAVIYNPEDDRAKIDYQRKEVLRTGAMRASEEEELMRRAREGMEDGEDAQFSVQIPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNVFYPDLIDKSKTPTYTLTPCEDPSQRDFAILRFSAGPPYEDIAFKIVNREWEYSYKHGFRCQFQNNIFQLWFHFKRFRYRR 935
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: A0A1S8WZG4 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=X801_04245 PE=4 SV=1)

HSP 1 Score: 362.459 bits (929), Expect = 1.494e-110
Identity = 232/595 (38.99%), Postives = 337/595 (56.64%), Query Frame = 3 
Query:  237 KDICGFTDDVNPFMDPNLTEQFIWKK----------NKRQI----KMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY--LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENE----CSTDTNVI-MNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTEN--------------GRDEA-LSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLKDNIKEEVNKT----------------------KPKD----------------------------EREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKG-DEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQE--AIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            K+  G+T++ NPF D  L+E F+WK+          +K +I    K   +  + ELE V++R  E ER REER+ E E++QR KE++ Y   G++ D TF L+QA +RS+IRI   R +PID L +YI ++ E     +  T VI + EPTQ+L+ L  + L +LLVDI      +  G+N +YW D   + EDEL KL R EN              GR  A +S+  ++++ + +   T  +   L    +  L+ G+   +D++Y+E    F +  +A+ RL++ H  NL+ +L+ L++ QG+    L P+  D  K   ++                       +P+D                            E E Y    Y P  +   E+    +D VIY  EDD  K+   RK+ L  G + +++E++L+  A++G ++ +D  F+ Q+ +ED SFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFN+ YPDLIDKSKTPT+ L+ C D  Q   AI+ F AGPPY+DIAFKIVN+EWE S + G++CQF  N+ Q+ FHFKR+RYR+
Sbjct:  350 KEYLGYTNEDNPFGDHRLSESFVWKQKLEAEGLTHLSKEEIQELQKKKMEENKLELESVRRRRAEREREREEREKEMEMMQRDKEAEYYRSWGQQED-TFHLEQAKLRSRIRIADGRAKPIDLLAKYIADQEEDAMASAEFTGVIELLEPTQFLVGLSVEDLEDLLVDIKVVYMQLEKGRNAEYWRDITTVAEDELNKLRRAENDSAGLSAAYGADSRGRSSASISQSVMQSVAETLKGKTYNQLAALERQIEPKLKGGE--GVDVTYWETLAQFVRAQMARTRLRDMHQENLRRKLECLRQSQGIVQEPLFPSGTDQPKPSTSQVVRSDAQLMPPPAVDKLRGEEPDEPEDTQPQIEDPHSAEAIRAARQAQLEAAAMVEEEMYDAACYSPPRVDPTEVA---LDAVIYNPEDDRAKIDYQRKEVLRTGAMRASEEEELMRRAREGMEDGEDAQFSVQIPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNVFYPDLIDKSKTPTYTLTPCEDPSQRDFAILRFSAGPPYEDIAFKIVNREWEYSYKHGFRCQFQNNIFQLWFHFKRFRYRR 938
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Match: A0A5K3EMI5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 355.525 bits (911), Expect = 2.736e-110
Identity = 232/598 (38.80%), Postives = 333/598 (55.69%), Query Frame = 3 
Query:  237 KDICGFTDDVNPFMDPNLTEQFIWKK---NKRQIKMD---CQTKEA--------ELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY--LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTD--------TNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE---------NGRDEA--LSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSS------LPTLKDNIKEEVNK----------------------------------------------TKPKD------EREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            KD  G+T++ NPF D +L+E F+W+K   NK    +D    QT +A        ELE V++R  E ER +EER+ E E++QR KE++ Y   G++ D TF L+QA +RS+IRI   R +PID L +YI +++E   +        + + + EPTQ+L+ L  + L +LLVDI      +  G+N +YW D  +IVEDEL KL + E          GR  +  +S   ++++ D + S T  +   L    +  L  G+   ID+ Y+E    F    +A+ RL+E H  +L+ +L  L++ QG+ +SS       P+   +  + V K                                              T P D      E + Y   +Y PVL+++ ++    ID V+Y A+DD  KL   RK  +  G L  T E++L+  A++G E+ D  F+    +ED SFLWSDKYRPRKPRF NRV+TGF WNKYNQTHYD+DNPPPK+VQGYKFNI YPDLID +KTPT+  + C +     I+ F AGPPY+DIAFKIVN+EWE S + G++CQF+  + Q+ FHFKR+RYR+
Sbjct:  114 KDYLGYTNEDNPFGDRHLSETFVWRKKIDNKGLSHLDNAQLQTLQAQKMEENRKELENVRRRRLEREREKEEREKELEMLQREKEAEYYKSWGQQED-TFHLEQAKLRSRIRIADGRAKPIDLLSKYIADQDEGGGNMAGSGDISSAIEVMEPTQFLVGLSIEDLEDLLVDIKVVYMELEKGQNVEYWRDMTVIVEDELRKLKQDEAADGGGPCDGGRHVSANISHSVLQSVADTLKSKTYAQLAALERQIQPKLRGGE--GIDVGYWEALSQFVAAQMARTRLRERHQDHLRRKLAFLQQMQGITTSSSDRNPIFPSGSGSTHQMVEKIRELQQQAAAKIHGEDQQDREEEKRQSEQLSVTSNQTEEESAGGPSTAPSDSAVIPNEPDPYDSAVYSPVLLNQSDV---EIDAVLYDAQDDWAKLEYQRKDVMHTGALRKTAEEELMKRAREGVEEGDAEFSVMAPLEDQSFLWSDKYRPRKPRFFNRVHTGFVWNKYNQTHYDLDNPPPKVVQGYKFNIFYPDLIDMTKTPTYTRTPCEEEPDFEILRFIAGPPYEDIAFKIVNREWEYSYKHGFRCQFHNTIFQLWFHFKRFRYRR 705
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Cavefish
Match: cactin (cactin [Source:NCBI gene;Acc:100126813])

HSP 1 Score: 328.561 bits (841), Expect = 2.708e-103
Identity = 212/556 (38.13%), Postives = 303/556 (54.50%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEA-----MKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSL-PTLKDNIKE-----------------------------EVNKTKP---KDEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
             G+T+  NPF D NL   F W+K               K + K   +    EL+KV++   E ER +  R+ E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LLVDI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E I       ++ +    T  +   L+ + +  ++ G   ++DI Y+E      ++ +A+ RL+E H   L+ +L KLK+EQG++S  L P +K+  +E                             EV  T+    +  + EY    Y P L+   EL    +D      E+D ++L   R+Q    G  S + ED  +  A++G   D+  F+ ++ +    +LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L   PDN    I+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  159 MGYTNADNPFGDNNLLGTFKWQKALEKKGIGHLGEKELKERNKRIQEENRRELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWAEQEDNFHLHQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVTDMDDLLVDIKVY-MQLEQGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALHMNIESKIQAGGS-NLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPIIKEEPEEHPASCRDGEEREENKEEEGEEDGEKSGGVEVVLTEEDLIQQSQAEYDSGRYSPTLLQSSEL---PLDTHTIDVEEDLQRLHLARRQLQVTGDASESAEDAFVRRAKEGMGGDEAQFSVELPLTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPSPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 706
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010480.1 (pep scaffold:Pmarinus_7.0:GL484446:794:2147:1 gene:ENSPMAG00000009491.1 transcript:ENSPMAT00000010480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 234.187 bits (596), Expect = 3.497e-73
Identity = 118/243 (48.56%), Postives = 151/243 (62.14%), Query Frame = 3 
Query: 1023 KLKEEQGLDSSSLPTLKDNIKEEVNKTKPKDEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            K  E  G    S+ T  D +++           EEY    Y P L+   EL    ++  +  AE+D ++L   RKQ    G    T ED     A++G   D+  F+ +V + D  +LWSDKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L     + + A + F AGPPY+DIAFKIV++EWE S R G++CQF  ++ Q+ FHFKRYRYR+
Sbjct:   39 KSGEGAGTAGDSVLTEADLVRQSC---------EEYEAGRYSPTLLPPDEL---PVEAHVMEAEEDNQRLYLARKQLQETGSAEDTAEDAFERRAREGMGTDEARFSVEVPLTDKLYLWSDKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKKSTPQYFLESSDGDREFATLRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANSIFQLWFHFKRYRYRR 269
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Sea Lamprey
Match: CACTIN (cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:HGNC:29938])

HSP 1 Score: 50.8322 bits (120), Expect = 5.584e-7
Identity = 30/65 (46.15%), Postives = 37/65 (56.92%), Query Frame = 3 
Query:  486 FDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDI 680
            F L QA +RSKIRI   R +PID L +Y+  E E   D  V M+EP  +L  L    L +LL DI
Sbjct:  308 FHLQQAKLRSKIRIKDGRAKPIDLLAKYVGMEEE---DLAVEMHEPYTFLNGLTASDLEDLLEDI 369
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Nematostella
Match: EDO39568 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9T3])

HSP 1 Score: 160.614 bits (405), Expect = 3.382e-47
Identity = 71/106 (66.98%), Postives = 84/106 (79.25%), Query Frame = 3 
Query: 1434 FDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            ++WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK+  P + L  C D    AI+ F AGPPY+DIAFK+VN+EWE S R G++CQF  N+ Q+ FHFKRYRYR+
Sbjct:    2 YEWNKYNQTHYDSDNPPPKIVQGYKFNIFYPDLIDKTVAPEYYLEPCSDTKDFAILRFHAGPPYEDIAFKVVNREWEYSHRHGFRCQFQNNIFQLWFHFKRYRYRR 107
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Nematostella
Match: EDO39569 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9T4])

HSP 1 Score: 84.3445 bits (207), Expect = 2.075e-18
Identity = 67/194 (34.54%), Postives = 110/194 (56.70%), Query Frame = 3 
Query:  240 DICGFTDDVNPFMDPNLTEQFIWKKNKR----------QIKMDCQTKEAE----LEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNYL-GRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNR 776
            ++ G+T+  NPF D +L + F+W K K           + ++  +T++ E    LE+V++R  E E     R+ E+E +QR KE++ +    K +  F L+QA++RS+IRI   R + ID L QYI+ +++   + ++ M+EP   L+ L +  L +LL DI  Y   M  GKN +YW D  II +DE+ KL +
Sbjct:   44 ELLGYTNTDNPFGDAHLLDSFVWHKVKEKHGENHLSEAEKRLRDKTRQEETRRQLEQVRQRRTEREHEMLLREEEKERLQREKEAEYFSEWEKQEDNFHLNQAMLRSQIRIKDGRAKAIDLLAQYISPDDD---NLDIKMHEPYTMLVGLTQSDLEDLLEDIKVY-LEMDQGKNAEYWQDITIICKDEIKKLRK 233
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Medaka
Match: cactin (cactin, spliceosome C complex subunit [Source:NCBI gene;Acc:101170546])

HSP 1 Score: 245.358 bits (625), Expect = 6.378e-71
Identity = 112/209 (53.59%), Postives = 140/209 (66.99%), Query Frame = 3 
Query: 1125 EYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            EY    Y P L+++ EL    +D      E+D  +L   R+     G  + + ED  +  A++G   D+  F+ +V V    +LW+DKYRPRKPRF NRV+TGF+WNKYNQTHYD DNPPPKIVQGYKFNI YPDLIDK  TP + L  CPDN    I+ F AGPPY+DIAFKIVN+EWE S R G++CQF   + Q+ FHFKRYRYR+
Sbjct:  642 EYDSGRYSPTLLTQSEL---PLDTHTITPEEDASRLQLARRLLQVTGDANESAEDAFVRRAREGMGTDEAQFSVEVPVTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPCPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR 847

HSP 2 Score: 113.235 bits (282), Expect = 1.168e-25
Identity = 106/314 (33.76%), Postives = 163/314 (51.91%), Query Frame = 3 
Query:  246 CGFTDDVNPFMDPNLTEQFIWKKN--------------KRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNY-LGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTE-NGRDEALSKESIEAMKDM----VLSG-TIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIKEEVNKTKPKDERE 1124
             G+T+  NPF D NL   F W+K               K + K+  +    EL+KV++   E ER +  R++E E++QR KE++++    + +  F L QA +RSKIRI   R +PID L +YI+ E++   D  V M+EP  +L  L    + +LL DI  Y   +  GKN  +W D   I EDE+ KL + E +G+     +E I          V  G T  +   L+ + +  +  G R ++DI Y+E      K+ +A+ RL+E H   L+ +L KLK+EQG++S  L  +   IKEE     P+DER+
Sbjct:  261 MGYTNADNPFGDNNLLGTFKWQKALVKKGIGHLGEKELKERNKLIQEENRRELQKVKQLRLEREREKAMREMELEMLQREKEAEHFKTWAEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDD---DLAVEMHEPYTFLNGLTVTDMDDLLEDIKVY-MELEQGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTAVSTDVQTVFKGKTYSQLQALHLNIESKIRAG-RSNLDIGYWESLLQQVKVYMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPI---IKEE-----PRDERD 561
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Planmine SMEST
Match: SMESG000026741.1 (SMESG000026741.1)

HSP 1 Score: 1049.27 bits (2712), Expect = 0.000e+0
Identity = 533/534 (99.81%), Postives = 533/534 (99.81%), Query Frame = 3 
Query:  150 LSPELVYHIENEYKEKYDATGYKRSNIRKKDICGFTDDVNPFMDPNLTEQFIWKKNKRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNYLGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTENGRDEALSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIKEEVNKTKPKDEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            LSPELVYHIENEYKEKYDATGYKRSNIRKKDICGFTDDVNPFMDPNLTEQFIWKKNKRQIKMDCQTKEAELEKVQKRMREHERLREERQIEQEIIQRAKESQNYLGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTENGRDEALSKESIEAMKDMVLSGTI EAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIKEEVNKTKPKDEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK
Sbjct:   39 LSPELVYHIENEYKEKYDATGYKRSNIRKKDICGFTDDVNPFMDPNLTEQFIWKKNKRQIKMDCQTKEAELEKVQKRMREHERLREERQIEQEIIQRAKESQNYLGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTENGRDEALSKESIEAMKDMVLSGTIDEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIKEEVNKTKPKDEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 572
[Close]
BLAST of Cactin, spliceosome C complex subunit vs. Planmine SMEST
Match: SMESG000061791.1 (SMESG000061791.1)

HSP 1 Score: 644.04 bits (1660), Expect = 0.000e+0
Identity = 343/545 (62.94%), Postives = 428/545 (78.53%), Query Frame = 3 
Query:  153 SPELVYHIENEYKEKYDATGYKRSN-IRKKDICGFTDDVNPFMDPNLTEQFIWKKNKRQIKMDCQTKEAELEKVQKXXXXXXXXXXXXXXXXXXXXXAKESQNYLGRKNDSTFDLDQAIVRSKIRINSDRGQPIDYLIQYINEE-NECSTDTNVIMNEPTQYLLMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTEN-GRDEALSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYYEYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIKEEVN-KTKP--------KDEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLISMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLIDKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGYKCQFYCNMLQVHFHFKRYRYRK 1751
            SPE +   E    E YDATG+KRS+ + K+ ICG+TDD NPFMDPNLT++F+WKK    ++++CQ K+AELE VQ+RM+EHERLREER +EQEI+QRAKE+QN+ GRK+DS FD++QA  RSKIRI   R +PID LIQY+NEE N  + + + I++EPTQ+L+ L K  L +LLVDI  YS NM PGKNTQYW D ++I EDEL ++ +TE+ GR E ++KE ++ MK M+L GTI E+ EL ND+K+MLETGDRRHID++YYEYFC+ A++LIAK+RLQE H  NL+I+L +LK EQGL     P     IK E    TKP        K EREEY +  Y PVL+S  ELG+E I+ VIY A+DDE+KL  MRK+F+ FG     +ED+L+ L Q+GDEK D++F++Q+ +E+ SFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYD+DNPPPKIVQGYKFNILYPDLIDK+KTPTFEL+ C D+DQ A+I FKAGPPY+DIAFKIVN+EWETSER GYKCQFY +MLQ++FHFKRYRYRK
Sbjct:   30 SPEFISKKEEIKNENYDATGFKRSSKVPKQAICGYTDDNNPFMDPNLTKEFVWKKKNNPVQLNCQEKQAELENVQRRMKEHERLREERLLEQEIMQRAKEAQNFRGRKSDSNFDIEQAKNRSKIRIAEGRAKPIDLLIQYVNEEENTINDNADAIIHEPTQFLVGLSKLDLDDLLVDIHEYSRNMEPGKNTQYWEDIRLITEDELKRVIKTEDDGRTEGVTKECVDDMKQMILQGTIEESTELLNDAKKMLETGDRRHIDVAYYEYFCSLARVLIAKKRLQERHSNNLRIKLNRLKHEQGLPIE--PLFPSAIKPEAQVDTKPTSSKKPEQKLEREEYDHSRYSPVLLSGEELGDEAIENVIYLADDDEKKLEFMRKKFIKFGSHKINQEDELIKLVQEGDEKGDLDFSEQIAIEEQSFLWSDKYRPRKPRFLNRVNTGFDWNKYNQTHYDMDNPPPKIVQGYKFNILYPDLIDKTKTPTFELTPCIDDDQYAMITFKAGPPYEDIAFKIVNREWETSERHGYKCQFYRDMLQLYFHFKRYRYRK 572
The following BLAST results are available for this feature:
BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CACTIN4.808e-10136.35cactin, spliceosome C complex subunit [Source:HGNC... [more]
CACTIN4.808e-10136.35cactin, spliceosome C complex subunit [Source:HGNC... [more]
CACTIN4.808e-10136.35cactin, spliceosome C complex subunit [Source:HGNC... [more]
CACTIN4.808e-10136.35cactin, spliceosome C complex subunit [Source:HGNC... [more]
CACTIN3.195e-7452.86cactin, spliceosome C complex subunit [Source:HGNC... [more]
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
cacn-11.122e-6261.69Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14][more]
cacn-15.382e-6250.00Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14][more]
cacn-12.022e-6061.69Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14][more]
cacn-12.022e-6061.69Cactin [Source:UniProtKB/Swiss-Prot;Acc:G5EG14][more]
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cactin1.464e-9236.96gene:FBgn0031114 transcript:FBtr0340400[more]
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
cactin1.670e-7154.07cactin [Source:NCBI gene;Acc:100126813][more]
cactin1.670e-1131.61cactin [Source:NCBI gene;Acc:100126813][more]
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CACTIN1.853e-10237.61cactin, spliceosome C complex subunit [Source:NCBI... [more]
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Cactin1.481e-9936.68cactin, spliceosome C complex subunit [Source:MGI ... [more]
Cactin3.819e-1832.47cactin, spliceosome C complex subunit [Source:MGI ... [more]
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BLAST of Cactin, spliceosome C complex subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8WUQ7|CATIN_HUMAN2.309e-10036.35Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3[more]
sp|Q9CS00|CATIN_MOUSE1.036e-9836.68Cactin OS=Mus musculus OX=10090 GN=Cactin PE=1 SV=... [more]
sp|Q9VR99|CATIN_DROME1.468e-9136.96Cactin OS=Drosophila melanogaster OX=7227 GN=cacti... [more]
sp|F1Q8W0|CATIN_DANRE1.261e-7054.07Cactin OS=Danio rerio OX=7955 GN=cactin PE=2 SV=1[more]
sp|F4I2J8|CATIN_ARATH4.656e-6530.34Cactin OS=Arabidopsis thaliana OX=3702 GN=CTN PE=1... [more]
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BLAST of Cactin, spliceosome C complex subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G7Y8W83.237e-11138.99Uncharacterized protein OS=Clonorchis sinensis OX=... [more]
A0A4S2LMZ63.294e-11138.99Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A3R7ETC61.068e-11038.99Cactin OS=Clonorchis sinensis OX=79923 GN=CACTIN P... [more]
A0A1S8WZG41.494e-11038.99Uncharacterized protein OS=Opisthorchis viverrini ... [more]
A0A5K3EMI52.736e-11038.80Uncharacterized protein OS=Mesocestoides corti OX=... [more]
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cactin2.708e-10338.13cactin [Source:NCBI gene;Acc:100126813][more]
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000010480.13.497e-7348.56pep scaffold:Pmarinus_7.0:GL484446:794:2147:1 gene... [more]
CACTIN5.584e-746.15cactin, spliceosome C complex subunit [Source:HGNC... [more]
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO395683.382e-4766.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395692.075e-1834.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cactin, spliceosome C complex subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cactin6.378e-7153.59cactin, spliceosome C complex subunit [Source:NCBI... [more]
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BLAST of Cactin, spliceosome C complex subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000026741.10.000e+099.81SMESG000026741.1[more]
SMESG000061791.10.000e+062.94SMESG000061791.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034043 ID=SMED30034043|Name=Cactin, spliceosome C complex subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1788bp
TTTAATGTCGTAAGAAATTTTAGTTTTAATTCAAAATGAAATTGAAAAAA
TCAAGACATCATTCTAGTTCTAGCAGTCCAGGAAAAAAAGAAGAAAAATC
TAAATCTAATTATCACCGTCATCATAAGCATGACAAAAAATATGATAAAT
TATCACCAGAACTCGTTTATCACATAGAAAATGAATATAAAGAAAAATAC
GATGCAACTGGTTATAAACGATCTAATATTCGGAAAAAAGATATTTGTGG
ATTCACCGATGATGTAAATCCGTTTATGGATCCAAATCTCACTGAACAAT
TTATTTGGAAGAAAAATAAACGTCAAATAAAAATGGATTGCCAAACTAAA
GAAGCAGAACTGGAAAAAGTTCAAAAACGAATGAGAGAACATGAAAGATT
ACGAGAGGAACGTCAAATAGAACAAGAAATTATCCAAAGGGCTAAAGAAT
CTCAAAATTATCTTGGCCGTAAAAACGACTCTACTTTTGATTTGGATCAA
GCCATTGTACGATCAAAAATACGAATTAACAGTGACCGTGGACAACCGAT
TGATTACTTAATCCAATATATAAATGAAGAAAATGAATGTTCAACCGACA
CTAACGTCATAATGAATGAACCAACACAGTATTTATTAATGCTGGATAAA
CAACAATTAGGAAATCTGCTGGTCGACATTGATAACTACTCCTGCAATAT
GGTCCCAGGTAAAAATACGCAATATTGGGCCGATTTTAAAATCATAGTCG
AAGATGAGTTATTCAAATTAAATCGAACAGAGAATGGTCGGGATGAAGCG
TTGAGCAAAGAATCTATTGAAGCTATGAAAGATATGGTGTTGTCTGGTAC
AATTGGCGAAGCTATTGAACTGTATAATGATTCGAAGCAAATGCTGGAAA
CTGGTGATCGCAGGCATATCGATATATCATATTATGAGTACTTTTGCAAC
TTTGCAAAGATCTTGATAGCTAAGCGACGACTCCAGGAAAATCACATGAG
AAATTTGCAAATTCAGTTAAAGAAACTTAAAGAAGAACAAGGACTTGACA
GTTCAAGTCTTCCAACACTAAAAGATAACATTAAAGAAGAAGTGAATAAA
ACAAAACCGAAGGATGAAAGGGAGGAATATATTTACAAACTGTATGAACC
AGTTTTAATATCAGAACATGAGTTAGGAGAAGAAGTAATCGATTATGTGA
TTTATAGGGCTGAGGACGACGAGCGGAAATTAATATCAATGAGGAAACAG
TTTTTGACGTTTGGTCATCTTTCTTCAACTAAAGAAGATCAACTTCTTTT
GTTAGCTCAAAAGGGTGATGAGAAGGATGATGTAAATTTCAATGATCAAG
TGATAGTCGAGGACAATTCTTTCCTATGGTCTGATAAATACCGGCCACGC
AAACCACGATTTCTGAATCGTGTTAATACTGGATTTGATTGGAATAAATA
TAATCAAACTCATTATGATATCGATAACCCGCCACCAAAAATTGTCCAAG
GATATAAGTTTAATATTCTCTACCCGGATCTTATTGATAAATCGAAAACT
CCGACATTTGAATTATCAGTCTGTCCAGACAACGATCAAGAAGCCATTAT
CAATTTCAAGGCTGGTCCTCCTTATCAGGATATTGCATTTAAAATTGTAA
ATAAAGAATGGGAGACTAGTGAAAGATTTGGTTATAAATGTCAATTCTAT
TGCAATATGCTTCAGGTTCATTTTCATTTCAAACGATATCGCTATCGGAA
ATAGATGTTTATATACTTTTTAATAAATTTTTTTTTAG
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protein sequence of SMED30034043-orf-1

>SMED30034043-orf-1 ID=SMED30034043-orf-1|Name=SMED30034043-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=573bp
MKLKKSRHHSSSSSPGKKEEKSKSNYHRHHKHDKKYDKLSPELVYHIENE
YKEKYDATGYKRSNIRKKDICGFTDDVNPFMDPNLTEQFIWKKNKRQIKM
DCQTKEAELEKVQKRMREHERLREERQIEQEIIQRAKESQNYLGRKNDST
FDLDQAIVRSKIRINSDRGQPIDYLIQYINEENECSTDTNVIMNEPTQYL
LMLDKQQLGNLLVDIDNYSCNMVPGKNTQYWADFKIIVEDELFKLNRTEN
GRDEALSKESIEAMKDMVLSGTIGEAIELYNDSKQMLETGDRRHIDISYY
EYFCNFAKILIAKRRLQENHMRNLQIQLKKLKEEQGLDSSSLPTLKDNIK
EEVNKTKPKDEREEYIYKLYEPVLISEHELGEEVIDYVIYRAEDDERKLI
SMRKQFLTFGHLSSTKEDQLLLLAQKGDEKDDVNFNDQVIVEDNSFLWSD
KYRPRKPRFLNRVNTGFDWNKYNQTHYDIDNPPPKIVQGYKFNILYPDLI
DKSKTPTFELSVCPDNDQEAIINFKAGPPYQDIAFKIVNKEWETSERFGY
KCQFYCNMLQVHFHFKRYRYRK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0002376immune system process
GO:0006397mRNA processing
GO:0007275multicellular organism development
GO:0008380RNA splicing
GO:0031665negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032088negative regulation of NF-kappaB transcription factor activity
GO:0032688negative regulation of interferon-beta production
GO:0032717negative regulation of interleukin-8 production
GO:0032720negative regulation of tumor necrosis factor production
GO:0034122negative regulation of toll-like receptor signaling pathway
GO:0045087innate immune response
GO:0060339negative regulation of type I interferon-mediated signaling pathway
GO:0071222cellular response to lipopolysaccharide
GO:0071347cellular response to interleukin-1
GO:0071356cellular response to tumor necrosis factor
GO:0000398mRNA splicing, via spliceosome
GO:0001933negative regulation of protein phosphorylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR019134Cactin_C
IPR018816Cactin_central
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0003723RNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005681spliceosomal complex
GO:0005829cytosol
GO:0016607nuclear speck
GO:0070062extracellular exosome
GO:0071013catalytic step 2 spliceosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 95..139
NoneNo IPR availableCOILSCoilCoilcoord: 314..334
NoneNo IPR availableSMARTSM01050CactinC_cactus_3coord: 448..572
e-value: 1.6E-70
score: 250.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..39
NoneNo IPR availablePANTHERPTHR21737:SF4CACTINcoord: 61..572
NoneNo IPR availablePANTHERPTHR21737POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3coord: 61..572
IPR018816Cactin, central domainPFAMPF10312Cactin_midcoord: 146..320
e-value: 1.1E-24
score: 87.3
IPR019134Cactin, C-terminalPFAMPF09732CactinC_cactuscoord: 448..572
e-value: 2.5E-53
score: 179.3