TNF receptor-associated factor 3

Overview
NameTNF receptor-associated factor 3
Smed IDSMED30034031
Length (bp)6618
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TNF receptor-associated factor 3 (SMED30034031) t-SNE clustered cells

Violin plots show distribution of expression levels for TNF receptor-associated factor 3 (SMED30034031) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TNF receptor-associated factor 3 (SMED30034031) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TNF receptor-associated factor 3 (SMED30034031) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30034031

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30034031 dd_Smed_v4_25195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.7734 bits (151), Expect = 5.377e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  388 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 477
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.7734 bits (151), Expect = 5.952e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  471 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 560
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.7734 bits (151), Expect = 5.952e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  471 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 560
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.7734 bits (151), Expect = 6.291e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  446 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 535
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.7734 bits (151), Expect = 6.291e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  446 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 535
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Zebrafish
Match: traf3 (TNF receptor-associated factor 3 [Source:ZFIN;Acc:ZDB-GENE-040801-257])

HSP 1 Score: 65.0846 bits (157), Expect = 7.058e-10
Identity = 31/90 (34.44%), Postives = 47/90 (52.22%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF + +G++D LL+WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  476 LSLFFVVMRGEYDALLQWPFKQKVTLMLMDQGPARKHLGDAFKPDPSSSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTV 565
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Zebrafish
Match: traf1 (TNF receptor-associated factor 1 [Source:ZFIN;Acc:ZDB-GENE-071120-4])

HSP 1 Score: 56.6102 bits (135), Expect = 3.170e-7
Identity = 33/91 (36.26%), Postives = 47/91 (51.65%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILR--QAAYVKDDNIYIKINV 4902
            + +FF I KG++D +L WP K+K                 F+ D  +  + QP ++ N+A+G P FF    LR  + AY KDD IYIK  V
Sbjct:  457 ISLFFVIMKGEYDPILSWPFKHKVTFFLLDQNQREHVIDAFRPDLSSMSFHQPVSDMNVASGCPLFFPLKKLRSPKHAYCKDDTIYIKCVV 547
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 62.3882 bits (150), Expect = 6.984e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  439 LSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 528
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 62.3882 bits (150), Expect = 7.268e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  464 LSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 553
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 62.7734 bits (151), Expect = 4.968e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  470 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 559
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 62.3882 bits (150), Expect = 5.119e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  445 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 534
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 62.3882 bits (150), Expect = 5.119e-9
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  445 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 534
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 55.0694 bits (131), Expect = 2.843e-7
Identity = 26/92 (28.26%), Postives = 47/92 (51.09%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQA--AYVKDDNIYIKINV 4902
            + ++F + +G+FD LL+WP + +                 TFK+D  +  + +P  E N+A+G P F     L  +   Y+KDD +++K+ V
Sbjct:  151 LSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAV 242
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 55.0694 bits (131), Expect = 2.843e-7
Identity = 26/92 (28.26%), Postives = 47/92 (51.09%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQA--AYVKDDNIYIKINV 4902
            + ++F + +G+FD LL+WP + +                 TFK+D  +  + +P  E N+A+G P F     L  +   Y+KDD +++K+ V
Sbjct:  151 LSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAV 242
[Close]
BLAST of TNF receptor-associated factor 3 vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2)

HSP 1 Score: 62.7734 bits (151), Expect = 2.858e-8
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  471 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 560
[Close]
BLAST of TNF receptor-associated factor 3 vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2)

HSP 1 Score: 62.7734 bits (151), Expect = 3.475e-8
Identity = 32/90 (35.56%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF I +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  470 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 559
[Close]
BLAST of TNF receptor-associated factor 3 vs. UniProt/SwissProt
Match: sp|O00463|TRAF5_HUMAN (TNF receptor-associated factor 5 OS=Homo sapiens OX=9606 GN=TRAF5 PE=1 SV=2)

HSP 1 Score: 56.9954 bits (136), Expect = 1.834e-6
Identity = 28/91 (30.77%), Postives = 48/91 (52.75%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQA--AYVKDDNIYIKINV 4902
            + ++F + +G+FD LL+WP + +                TFK D  +  + +P  E N+A+G P F    +L  A  AY+KDD +++K+ V
Sbjct:  459 LSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAV 549
[Close]
BLAST of TNF receptor-associated factor 3 vs. TrEMBL
Match: A0A3Q3A2F5 (MATH domain-containing protein OS=Kryptolebias marmoratus OX=37003 PE=4 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 9.637e-9
Identity = 30/82 (36.59%), Postives = 46/82 (56.10%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNKT-----------FKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKI 4896
            + +FF + +G++D LL WP K KT           FK D  +  + +P  E N+A+G P F  Q +L   +Y+KDD I+IK+
Sbjct:   52 LSLFFVVMRGEYDALLPWPFKQKTQTFTLKHLGDAFKPDPNSSSFRRPVAEMNIASGCPLFVSQSVLETGSYIKDDTIFIKV 133
[Close]
BLAST of TNF receptor-associated factor 3 vs. TrEMBL
Match: H2YYB2 (MATH domain-containing protein OS=Ciona savignyi OX=51511 PE=4 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 1.375e-8
Identity = 30/90 (33.33%), Postives = 51/90 (56.67%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF + KG++D LL WP + K                 TF+ D  +  + QPT++ N+A+G P F    +++ ++YVK+D IYI+I+V
Sbjct:   61 MSLFFVVMKGEYDALLPWPFRQKVTLMLLDQGVDRRHLSDTFRPDPTSSSFKQPTSDMNIASGCPLFVAHSVIKGSSYVKEDTIYIRIHV 150
[Close]
BLAST of TNF receptor-associated factor 3 vs. TrEMBL
Match: H2YBM2 (MATH domain-containing protein OS=Ciona savignyi OX=51511 PE=4 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 3.505e-8
Identity = 28/88 (31.82%), Postives = 51/88 (57.95%), Query Frame = 1 
Query: 4690 IFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            +FF + KG++D LL WP + K                 TF+ D  +  + QPT++ N+A+G P F   ++++ ++YVK+D I+++I+V
Sbjct:   56 LFFVVMKGEYDALLPWPFRQKVTLMLLDQGMDRRHLSDTFRPDPTSSSFKQPTSDMNIASGCPLFVAHNVIKGSSYVKEDTIFLRIHV 143
[Close]
BLAST of TNF receptor-associated factor 3 vs. TrEMBL
Match: A0A3B1IJ18 (TNF receptor associated factor 3 OS=Astyanax mexicanus OX=7994 GN=TRAF3 PE=4 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 9.122e-8
Identity = 31/90 (34.44%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF + +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:   59 LSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTV 148
[Close]
BLAST of TNF receptor-associated factor 3 vs. TrEMBL
Match: H2YBL7 (MATH domain-containing protein OS=Ciona savignyi OX=51511 PE=4 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 2.278e-7
Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF + KG++D LL WP + K                 TFK D  +  + +PT++ N+A+G P F   +++  ++YVK+D I+++I+V
Sbjct:   61 MSLFFVVMKGEYDALLPWPFRQKVTLMLLDQGMDRRHLSDTFKPDPTSSSFKKPTSDMNIASGCPLFVAHNVIEGSSYVKEDTIFLRIHV 150
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Cavefish
Match: ENSAMXT00000035169.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:3354744:3362219:1 gene:ENSAMXG00000029095.1 transcript:ENSAMXT00000035169.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 3.455e-11
Identity = 31/90 (34.44%), Postives = 46/90 (51.11%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF + +G++D LL WP K K                  FK D  +  + +PT E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:   59 LSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTV 148
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 62.3882 bits (150), Expect = 4.498e-9
Identity = 36/95 (37.89%), Postives = 49/95 (51.58%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILR--QAAYVKDDNIYIKINVIKDY 4914
            + +FF I KGD+D LL WP K K                 F+ D R+  + +P +E N+A+G P FF    LR  + AYVKDD ++IK  V   Y
Sbjct:  424 ISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHVVDAFRPDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVVDPSY 518
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 62.003 bits (149), Expect = 5.560e-9
Identity = 36/95 (37.89%), Postives = 49/95 (51.58%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILR--QAAYVKDDNIYIKINVIKDY 4914
            + +FF I KGD+D LL WP K K                 F+ D R+  + +P +E N+A+G P FF    LR  + AYVKDD ++IK  V   Y
Sbjct:  447 ISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHVVDAFRPDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVVDPSY 541
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.9214 bits (141), Expect = 1.057e-8
Identity = 28/90 (31.11%), Postives = 48/90 (53.33%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF + +G++D LL WP + +                 TFK D  +  + +PT++ N+A+G P F     L  A+Y++DD I+IK+ V
Sbjct:  380 LSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFVSHVALESASYLQDDTIFIKVVV 469
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 4.558e-6
Identity = 23/90 (25.56%), Postives = 45/90 (50.00%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF + +G++D LLEWP + +                 TF  D  +  + +P  + N+A+G P F     L  ++Y+ DD +++++ V
Sbjct:  323 LSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPASGSFRRPDGDMNVASGCPLFVSHVALEGSSYLVDDTVFVRVVV 412
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4])

HSP 1 Score: 61.6178 bits (148), Expect = 2.386e-9
Identity = 32/94 (34.04%), Postives = 48/94 (51.06%), Query Frame = 1 
Query: 4675 NFVVRIFFQICKGDFDELLEWPLKNK----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINVIK 4908
            N  V +FF I +G+FD LL WP + K                 F+ D  +  + +P  E N+A+G P F   + L Q AY++DD +++KI V K
Sbjct:  385 NHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQDNVEHVIDAFRPDPSSSSFQRPRAEMNIASGCPLFCSHEQLTQHAYIRDDTMFLKIIVDK 478
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36])

HSP 1 Score: 58.9214 bits (141), Expect = 1.923e-8
Identity = 30/89 (33.71%), Postives = 47/89 (52.81%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF + +G+FD LL WP + K                TF+ D  +  + +PT+  N+A+G P F     L+  AYV+DD ++IKI V
Sbjct:  433 LSLFFVLMRGEFDALLPWPFRQKVTFKLLDQDRVHDIGDTFRPDPTSSSFKRPTSNMNIASGCPLFISHTNLQTRAYVRDDTMFIKIAV 521
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Nematostella
Match: EDO49545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGK7])

HSP 1 Score: 53.5286 bits (127), Expect = 7.575e-7
Identity = 33/94 (35.11%), Postives = 48/94 (51.06%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-TF----KSDQRNP----------------CYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + ++  I KGD+D LLEWP K K TF    +S+++N                  + +PT +ENL  G P F   ++L    YVKDD ++IK  V
Sbjct:  309 LSLYIIIMKGDYDALLEWPFKQKITFYLIDQSEKQNHRTHLLSPNRSLPNIKVVFNRPTVKENLGIGNPCFVPNEVLESGEYVKDDVMFIKAVV 402
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601])

HSP 1 Score: 63.1586 bits (152), Expect = 1.764e-9
Identity = 30/90 (33.33%), Postives = 45/90 (50.00%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNK-----------------TFKSDQRNPCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINV 4902
            + +FF + +G++D LL WP K K                  FK D  +  + +P  E N+A+G P F  Q +L    Y+KDD I+IK+ V
Sbjct:  353 LSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPDPSSSSFRRPVAEMNIASGCPLFVSQSVLESGTYIKDDTIFIKVTV 442
[Close]
BLAST of TNF receptor-associated factor 3 vs. Ensembl Medaka
Match: ENSORLT00000001369.2 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:101170323])

HSP 1 Score: 52.373 bits (124), Expect = 6.199e-6
Identity = 31/95 (32.63%), Postives = 42/95 (44.21%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNKT-----------------FKSDQRNPCYIQPTTE--ENLAAGGPAFFQQDILR---QAAYVKDDNIYIKINV 4902
            + ++  +  GDFD LL WP K                    F+ D  N C+ QP  E   N+A G P F   D L     A YVKDD +++K+ V
Sbjct:  483 LSLYVVLMPGDFDALLPWPFKQTVSLSVLDQSGARNHQSFNFRPDPTNTCFHQPAAESASNVAVGFPCFISLDALEAPGNAVYVKDDTLFVKVKV 577
[Close]
BLAST of TNF receptor-associated factor 3 vs. Planmine SMEST
Match: SMESG000016682.1 (SMESG000016682.1)

HSP 1 Score: 73.1738 bits (178), Expect = 8.859e-28
Identity = 38/78 (48.72%), Postives = 47/78 (60.26%), Query Frame = 1 
Query: 4072 HPKICEMNEDKCELCGEIDIWKELETTL*NLIERQICDEYKNKCPN*FNMKESVTLTEHWETCSRKAIMCPLKLLNCK 4305
            H KIC   E+KCE CG ID W ++E    N  E QICD Y+  C N  + K+ V L EHW  CS K + CPL+L NC+
Sbjct: 1498 HHKICIKREEKCEFCGVIDEWIKIEMQHRNPKEEQICDRYEGVCANNCDKKDKVKLKEHWNECSGKPVKCPLELFNCQ 1575

HSP 2 Score: 46.2098 bits (108), Expect = 8.859e-28
Identity = 31/75 (41.33%), Postives = 45/75 (60.00%), Query Frame = 2 
Query: 3740 HEFEERFMCCECKKLLIEASQTE**C*ICR*WAIKVIRKE-LKLPRLGKTTIKTLENTRPDHAANH*ISNLLVKC 3961
            ++ +ER  CC+CK+LLI A QT+  C IC    I+VI  + +K P   +T  +  + T  D A N  I+NLLV+C
Sbjct: 1381 NDIKERLKCCKCKELLIGARQTKCGCRICTDCTIEVIETQTIKCPGCDETIERDEDPTTMDKATNKEINNLLVQC 1455

HSP 3 Score: 42.743 bits (99), Expect = 8.859e-28
Identity = 22/93 (23.66%), Postives = 53/93 (56.99%), Query Frame = 3 
Query: 4332 KHLKENNVEHLTTMIEAIEITAMSINDSKDNLKSHIVLIKEMLNAREYFKKLEEQMIQKTILIDRKLKEITIQQKKCEANMPTSEELTITPYV 4610
            KH+ EN++EH   M++ I + A  +   +    +   +I+E+L +R+ F+K +   ++K + +++K++++T   K+ E N   + +    P++
Sbjct: 1585 KHMMENSIEHTEIMMKTIGMLAWEVKSLRTENDAQKAIIREILESRKNFEKSQGDTLKKMVEMEKKMQQMTNNIKELETNNSIARKYLTAPFI 1677

HSP 4 Score: 23.0978 bits (48), Expect = 8.859e-28
Identity = 14/30 (46.67%), Postives = 16/30 (53.33%), Query Frame = 3 
Query: 3972 GF*KETTNHQEVYELIEVKCKKCNDTITPK 4061
            G  KE  NH    E  E+ C+KC  TIT K
Sbjct: 1464 GLMKEAENHANECEYNEILCEKCQ-TITTK 1492

HSP 5 Score: 75.0998 bits (183), Expect = 6.789e-13
Identity = 43/98 (43.88%), Postives = 65/98 (66.33%), Query Frame = 2 
Query: 2180 TNVKSNEGQTPLMIAVAGYVSTTVLRK*IENGSLLRE-DNRSRNVLIYDMKSRFAT--KFIINNAAKKDTYVLCRTSRPLKEAIEKGQDETSKAIIEW 2464
            +N+ + EGQTPLM AVA   STTVLR+ ++ GS  +E DN   +VL Y +KSR A+  KFI +NA  ++  ++ +T + L EAI+  QDE +  +++W
Sbjct:  547 SNIPNEEGQTPLMFAVAADASTTVLRELLKTGSSFKEKDNGGNSVLHYALKSRQASAIKFITSNATTREREMMGKTIQTLWEAIDAKQDEAAANLMKW 644

HSP 6 Score: 66.6254 bits (161), Expect = 2.815e-10
Identity = 30/83 (36.14%), Postives = 46/83 (55.42%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNKTF-----KSDQRNPCYI-------QPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKI 4896
            + +F ++ +GD+DELL WP K         + D RNP          +PTT+ N A G P F+ Q  LR   ++++DN+YIK+
Sbjct: 1729 ISVFIRVGRGDYDELLTWPFKQNMILTMKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYIKL 1811

HSP 7 Score: 54.6842 bits (130), Expect = 1.267e-6
Identity = 25/40 (62.50%), Postives = 32/40 (80.00%), Query Frame = 2 
Query: 1274 LRELMRTGSVLKEKHTGGKTVLAYAMKSKEASAIEFIKPN 1393
            LREL++TGS  KEK  GG +VL YA+KS++ASAI+FI  N
Sbjct:  571 LRELLKTGSSFKEKDNGGNSVLHYALKSRQASAIKFITSN 610
[Close]
BLAST of TNF receptor-associated factor 3 vs. Planmine SMEST
Match: SMESG000016682.1 (SMESG000016682.1)

HSP 1 Score: 73.1738 bits (178), Expect = 8.930e-28
Identity = 38/78 (48.72%), Postives = 47/78 (60.26%), Query Frame = 1 
Query: 4072 HPKICEMNEDKCELCGEIDIWKELETTL*NLIERQICDEYKNKCPN*FNMKESVTLTEHWETCSRKAIMCPLKLLNCK 4305
            H KIC   E+KCE CG ID W ++E    N  E QICD Y+  C N  + K+ V L EHW  CS K + CPL+L NC+
Sbjct: 1500 HHKICIKREEKCEFCGVIDEWIKIEMQHRNPKEEQICDRYEGVCANNCDKKDKVKLKEHWNECSGKPVKCPLELFNCQ 1577

HSP 2 Score: 46.2098 bits (108), Expect = 8.930e-28
Identity = 31/75 (41.33%), Postives = 45/75 (60.00%), Query Frame = 2 
Query: 3740 HEFEERFMCCECKKLLIEASQTE**C*ICR*WAIKVIRKE-LKLPRLGKTTIKTLENTRPDHAANH*ISNLLVKC 3961
            ++ +ER  CC+CK+LLI A QT+  C IC    I+VI  + +K P   +T  +  + T  D A N  I+NLLV+C
Sbjct: 1383 NDIKERLKCCKCKELLIGARQTKCGCRICTDCTIEVIETQTIKCPGCDETIERDEDPTTMDKATNKEINNLLVQC 1457

HSP 3 Score: 42.743 bits (99), Expect = 8.930e-28
Identity = 22/93 (23.66%), Postives = 53/93 (56.99%), Query Frame = 3 
Query: 4332 KHLKENNVEHLTTMIEAIEITAMSINDSKDNLKSHIVLIKEMLNAREYFKKLEEQMIQKTILIDRKLKEITIQQKKCEANMPTSEELTITPYV 4610
            KH+ EN++EH   M++ I + A  +   +    +   +I+E+L +R+ F+K +   ++K + +++K++++T   K+ E N   + +    P++
Sbjct: 1587 KHMMENSIEHTEIMMKTIGMLAWEVKSLRTENDAQKAIIREILESRKNFEKSQGDTLKKMVEMEKKMQQMTNNIKELETNNSIARKYLTAPFI 1679

HSP 4 Score: 23.0978 bits (48), Expect = 8.930e-28
Identity = 14/30 (46.67%), Postives = 16/30 (53.33%), Query Frame = 3 
Query: 3972 GF*KETTNHQEVYELIEVKCKKCNDTITPK 4061
            G  KE  NH    E  E+ C+KC  TIT K
Sbjct: 1466 GLMKEAENHANECEYNEILCEKCQ-TITTK 1494

HSP 5 Score: 75.0998 bits (183), Expect = 6.677e-13
Identity = 43/98 (43.88%), Postives = 65/98 (66.33%), Query Frame = 2 
Query: 2180 TNVKSNEGQTPLMIAVAGYVSTTVLRK*IENGSLLRE-DNRSRNVLIYDMKSRFAT--KFIINNAAKKDTYVLCRTSRPLKEAIEKGQDETSKAIIEW 2464
            +N+ + EGQTPLM AVA   STTVLR+ ++ GS  +E DN   +VL Y +KSR A+  KFI +NA  ++  ++ +T + L EAI+  QDE +  +++W
Sbjct:  547 SNIPNEEGQTPLMFAVAADASTTVLRELLKTGSSFKEKDNGGNSVLHYALKSRQASAIKFITSNATTREREMMGKTIQTLWEAIDAKQDEAAANLMKW 644

HSP 6 Score: 66.6254 bits (161), Expect = 2.863e-10
Identity = 30/83 (36.14%), Postives = 46/83 (55.42%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNKTF-----KSDQRNPCYI-------QPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKI 4896
            + +F ++ +GD+DELL WP K         + D RNP          +PTT+ N A G P F+ Q  LR   ++++DN+YIK+
Sbjct: 1731 ISVFIRVGRGDYDELLTWPFKQNMILTMKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYIKL 1813

HSP 7 Score: 54.6842 bits (130), Expect = 1.267e-6
Identity = 25/40 (62.50%), Postives = 32/40 (80.00%), Query Frame = 2 
Query: 1274 LRELMRTGSVLKEKHTGGKTVLAYAMKSKEASAIEFIKPN 1393
            LREL++TGS  KEK  GG +VL YA+KS++ASAI+FI  N
Sbjct:  571 LRELLKTGSSFKEKDNGGNSVLHYALKSRQASAIKFITSN 610
[Close]
BLAST of TNF receptor-associated factor 3 vs. Planmine SMEST
Match: SMESG000016682.1 (SMESG000016682.1)

HSP 1 Score: 73.1738 bits (178), Expect = 9.004e-28
Identity = 38/78 (48.72%), Postives = 47/78 (60.26%), Query Frame = 1 
Query: 4072 HPKICEMNEDKCELCGEIDIWKELETTL*NLIERQICDEYKNKCPN*FNMKESVTLTEHWETCSRKAIMCPLKLLNCK 4305
            H KIC   E+KCE CG ID W ++E    N  E QICD Y+  C N  + K+ V L EHW  CS K + CPL+L NC+
Sbjct: 1493 HHKICIKREEKCEFCGVIDEWIKIEMQHRNPKEEQICDRYEGVCANNCDKKDKVKLKEHWNECSGKPVKCPLELFNCQ 1570

HSP 2 Score: 46.2098 bits (108), Expect = 9.004e-28
Identity = 31/75 (41.33%), Postives = 45/75 (60.00%), Query Frame = 2 
Query: 3740 HEFEERFMCCECKKLLIEASQTE**C*ICR*WAIKVIRKE-LKLPRLGKTTIKTLENTRPDHAANH*ISNLLVKC 3961
            ++ +ER  CC+CK+LLI A QT+  C IC    I+VI  + +K P   +T  +  + T  D A N  I+NLLV+C
Sbjct: 1376 NDIKERLKCCKCKELLIGARQTKCGCRICTDCTIEVIETQTIKCPGCDETIERDEDPTTMDKATNKEINNLLVQC 1450

HSP 3 Score: 42.743 bits (99), Expect = 9.004e-28
Identity = 22/93 (23.66%), Postives = 53/93 (56.99%), Query Frame = 3 
Query: 4332 KHLKENNVEHLTTMIEAIEITAMSINDSKDNLKSHIVLIKEMLNAREYFKKLEEQMIQKTILIDRKLKEITIQQKKCEANMPTSEELTITPYV 4610
            KH+ EN++EH   M++ I + A  +   +    +   +I+E+L +R+ F+K +   ++K + +++K++++T   K+ E N   + +    P++
Sbjct: 1580 KHMMENSIEHTEIMMKTIGMLAWEVKSLRTENDAQKAIIREILESRKNFEKSQGDTLKKMVEMEKKMQQMTNNIKELETNNSIARKYLTAPFI 1672

HSP 4 Score: 23.0978 bits (48), Expect = 9.004e-28
Identity = 14/30 (46.67%), Postives = 16/30 (53.33%), Query Frame = 3 
Query: 3972 GF*KETTNHQEVYELIEVKCKKCNDTITPK 4061
            G  KE  NH    E  E+ C+KC  TIT K
Sbjct: 1459 GLMKEAENHANECEYNEILCEKCQ-TITTK 1487

HSP 5 Score: 75.0998 bits (183), Expect = 7.018e-13
Identity = 43/98 (43.88%), Postives = 65/98 (66.33%), Query Frame = 2 
Query: 2180 TNVKSNEGQTPLMIAVAGYVSTTVLRK*IENGSLLRE-DNRSRNVLIYDMKSRFAT--KFIINNAAKKDTYVLCRTSRPLKEAIEKGQDETSKAIIEW 2464
            +N+ + EGQTPLM AVA   STTVLR+ ++ GS  +E DN   +VL Y +KSR A+  KFI +NA  ++  ++ +T + L EAI+  QDE +  +++W
Sbjct:  547 SNIPNEEGQTPLMFAVAADASTTVLRELLKTGSSFKEKDNGGNSVLHYALKSRQASAIKFITSNATTREREMMGKTIQTLWEAIDAKQDEAAANLMKW 644

HSP 6 Score: 66.6254 bits (161), Expect = 2.814e-10
Identity = 30/83 (36.14%), Postives = 46/83 (55.42%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNKTF-----KSDQRNPCYI-------QPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKI 4896
            + +F ++ +GD+DELL WP K         + D RNP          +PTT+ N A G P F+ Q  LR   ++++DN+YIK+
Sbjct: 1724 ISVFIRVGRGDYDELLTWPFKQNMILTMKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYIKL 1806

HSP 7 Score: 54.6842 bits (130), Expect = 1.299e-6
Identity = 25/40 (62.50%), Postives = 32/40 (80.00%), Query Frame = 2 
Query: 1274 LRELMRTGSVLKEKHTGGKTVLAYAMKSKEASAIEFIKPN 1393
            LREL++TGS  KEK  GG +VL YA+KS++ASAI+FI  N
Sbjct:  571 LRELLKTGSSFKEKDNGGNSVLHYALKSRQASAIKFITSN 610
[Close]
BLAST of TNF receptor-associated factor 3 vs. Planmine SMEST
Match: SMESG000022654.1 (SMESG000022654.1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.161e-27
Identity = 37/78 (47.44%), Postives = 45/78 (57.69%), Query Frame = 1 
Query: 4072 HPKICEMNEDKCELCGEIDIWKELETTL*NLIERQICDEYKNKCPN*FNMKESVTLTEHWETCSRKAIMCPLKLLNCK 4305
            H K+C   E+KCE CG ID W  +E    N  E QICD Y+  C N  N K+ V L EHW  C  K + CPL+L NC+
Sbjct: 2077 HHKVCISREEKCEFCGAIDEWINIEKEHRNPKEEQICDLYEGICANHCNQKDKVKLKEHWNECIGKPVKCPLELFNCQ 2154

HSP 2 Score: 50.0618 bits (118), Expect = 1.161e-27
Identity = 32/72 (44.44%), Postives = 40/72 (55.56%), Query Frame = 2 
Query: 3749 EERFMCCECKKLLIEASQTE**C*ICR*WAIKVIR-KELKLPRLGKTTIKTLENTRPDHAANH*ISNLLVKC 3961
            EER  CC+CK LLI A QT+  C IC    I++I  K LK P   +      + T  D A N  I+NLLV+C
Sbjct: 1963 EERLKCCKCKGLLIGAIQTKCGCRICTDCTIEMIETKILKCPGCDEAIKGDEDPTTIDKATNKEINNLLVQC 2034

HSP 3 Score: 41.2022 bits (95), Expect = 1.161e-27
Identity = 24/93 (25.81%), Postives = 50/93 (53.76%), Query Frame = 3 
Query: 4332 KHLKENNVEHLTTMIEAIEITAMSINDSKDNLKSHIVLIKEMLNAREYFKKLEEQMIQKTILIDRKLKEITIQQKKCEANMPTSEELTITPYV 4610
            KH+ EN+++H   M++ I + A  +   +    +   L++E+L +R+ F+K +    +K   ++ K+++I    K  E   P S +L  TP++
Sbjct: 2164 KHMIENSIKHTEIMMKTIGMIAWEMKSLRTETDAQKALMREILESRKNFEKSQAITPKKIAEMEEKIQQIISSIKDLETTSPISRKLPTTPFI 2256

HSP 4 Score: 23.0978 bits (48), Expect = 1.161e-27
Identity = 10/22 (45.45%), Postives = 12/22 (54.55%), Query Frame = 3 
Query: 3975 F*KETTNHQEVYELIEVKCKKC 4040
            F KE  +H    E  E+ CKKC
Sbjct: 2044 FVKEAESHANECEYNEIPCKKC 2065

HSP 5 Score: 87.4261 bits (215), Expect = 1.428e-16
Identity = 53/127 (41.73%), Postives = 77/127 (60.63%), Query Frame = 2 
Query: 2093 NTLLHRVLKGNYRERII*TLKAMEDYKQHTNVKSNEGQTPLMIAVAGYVSTTVLRK*IENGSLLRE-DNRSRNVLIYDMKSRFAT--KFIINNAAKKDTYVLCRTSRPLKEAIEKGQDETSKAIIEW 2464
            N  LH  ++    +RII  ++ M+     +N+ + EGQTPLM AVA   STTVLRK +  GS  +E DN   NVL Y +KSR A+  KFI +NA  ++  ++ +T + L EAIE  QDE +  +++W
Sbjct:  912 NVPLHFAVQHRNIQRIIDIIQFMQKCGHTSNIPNKEGQTPLMFAVAADASTTVLRKLLRTGSSFKEKDNGENNVLHYALKSRQASAMKFITSNATIREREMMGKTIQTLWEAIEAKQDEAAANLMKW 1038

HSP 6 Score: 48.9062 bits (115), Expect = 1.389e-13
Identity = 24/59 (40.68%), Postives = 35/59 (59.32%), Query Frame = 3 
Query: 1458 DTTTASIVKWAGGPDKIKILEVNKFE*NENIFLKKTIKAKRNFPKTIKALLKRSRI*FT 1634
            D   A+++KW      +K+ ++N    N N+ LK+TI A   FPKTIK +LK  R+ FT
Sbjct: 1029 DEAAANLMKWTYEGSSLKVFDLNYIVRNRNVLLKETIYAYYPFPKTIKTILKWERLKFT 1087

HSP 7 Score: 48.521 bits (114), Expect = 1.389e-13
Identity = 23/40 (57.50%), Postives = 30/40 (75.00%), Query Frame = 2 
Query: 1274 LRELMRTGSVLKEKHTGGKTVLAYAMKSKEASAIEFIKPN 1393
            LR+L+RTGS  KEK  G   VL YA+KS++ASA++FI  N
Sbjct:  965 LRKLLRTGSSFKEKDNGENNVLHYALKSRQASAMKFITSN 1004

HSP 8 Score: 61.6178 bits (148), Expect = 8.698e-9
Identity = 31/91 (34.07%), Postives = 48/91 (52.75%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNKTF-----KSDQRN-------PCYIQPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKINVIKDYKS 4920
            + +F  + KG++DELL WP K         + + RN       P   +PTT+ N A G P F+ Q  LR   ++++DN+YI + V K  K+
Sbjct: 2308 ISVFVSVGKGEYDELLTWPFKQNMILTMKGREEYRNTIRTGNEPQMGRPTTDWNTAIGTPFFYSQQRLRGEGFLREDNLYITLEVEKPDKT 2398

HSP 9 Score: 40.0466 bits (92), Expect = 2.044e-6
Identity = 20/68 (29.41%), Postives = 39/68 (57.35%), Query Frame = 3 
Query:  765 WVKDKNFFDILGGITLMMKDYSRGKSKPTKITTIIERIPVLFTITDL--NKKINHVLITKNEMRILEI 962
            WV+ K +  I+     +  DY++G   P ++  I E+IP++FT+ D+  N  ++  +  +N  RI++I
Sbjct:  863 WVEGKGWMRIVNKAGKIAMDYAKGARSPPEMDLIKEKIPMIFTMADVEGNVPLHFAVQHRNIQRIIDI 930

HSP 10 Score: 33.113 bits (74), Expect = 2.044e-6
Identity = 12/29 (41.38%), Postives = 17/29 (58.62%), Query Frame = 2 
Query:  962 MNIMEVCGQNTNISNSKGQIRLMIAIGID 1048
            +  M+ CG  +NI N +GQ  LM A+  D
Sbjct:  931 IQFMQKCGHTSNIPNKEGQTPLMFAVAAD 959
[Close]
BLAST of TNF receptor-associated factor 3 vs. Planmine SMEST
Match: SMESG000066529.1 (SMESG000066529.1)

HSP 1 Score: 69.3218 bits (168), Expect = 2.631e-26
Identity = 36/78 (46.15%), Postives = 47/78 (60.26%), Query Frame = 1 
Query: 4072 HPKICEMNEDKCELCGEIDIWKELETTL*NLIERQICDEYKNKCPN*FNMKESVTLTEHWETCSRKAIMCPLKLLNCK 4305
            H K+C   E+KCE CG ID W ++E    N  E QICD Y+  C N  + ++ V L EHW  CS K + CPL+L NC+
Sbjct: 3512 HHKVCIKREEKCEFCGVIDEWIKIEMEHRNPKEEQICDLYEGICTNNCDKRDKVKLKEHWNECSGKPVKCPLELFNCQ 3589

HSP 2 Score: 46.2098 bits (108), Expect = 2.631e-26
Identity = 32/75 (42.67%), Postives = 45/75 (60.00%), Query Frame = 2 
Query: 3740 HEFEERFMCCECKKLLIEASQTE**C*ICR*WAIKVIRKE-LKLPRLGKTTIKTLENTRPDHAANH*ISNLLVKC 3961
            ++ +ER  CC+CK+LLI A QT+  C IC    I+VI  E +K P   +T  +  + T  D A N  I+NLLV+C
Sbjct: 3395 NDIKERLKCCKCKELLIGARQTKCGCRICTDCTIEVIETETIKCPGCDETFERDEDPTTMDKATNKEINNLLVQC 3469

HSP 3 Score: 42.3578 bits (98), Expect = 2.631e-26
Identity = 23/93 (24.73%), Postives = 51/93 (54.84%), Query Frame = 3 
Query: 4332 KHLKENNVEHLTTMIEAIEITAMSINDSKDNLKSHIVLIKEMLNAREYFKKLEEQMIQKTILIDRKLKEITIQQKKCEANMPTSEELTITPYV 4610
            KH+ EN++EH   M++ I + A  +   +    +   LI+E+L +R+ F++ +   ++K   +++K+++IT   K+ E N     +    P++
Sbjct: 3599 KHMIENSIEHTEIMMKTIGMLAWEVKSLRTENDTQKALIREILESRKNFERSQGNTLKKMAEMEKKMQQITNSLKELETNSSVVRKYLTAPFI 3691

HSP 4 Score: 22.3274 bits (46), Expect = 2.631e-26
Identity = 13/30 (43.33%), Postives = 15/30 (50.00%), Query Frame = 3 
Query: 3972 GF*KETTNHQEVYELIEVKCKKCNDTITPK 4061
            G  KE  +H    E  E+ C KC  TIT K
Sbjct: 3478 GLMKEAESHTNECEYNEISCGKCQ-TITTK 3506

HSP 5 Score: 84.7297 bits (208), Expect = 9.726e-16
Identity = 50/127 (39.37%), Postives = 78/127 (61.42%), Query Frame = 2 
Query: 2093 NTLLHRVLKGNYRERII*TLKAMEDYKQHTNVKSNEGQTPLMIAVAGYVSTTVLRK*IENGSLLRE-DNRSRNVLIYDMKSRFAT--KFIINNAAKKDTYVLCRTSRPLKEAIEKGQDETSKAIIEW 2464
            N  LH  ++    +RI+  ++ M+     +N+ + EGQTPLM AVA   STTVLR+ ++ GS  +E DN   NVL Y +KSR A+  KFI +NA  ++  ++ +T + L EAI+  QDE +  +++W
Sbjct: 2595 NVPLHIAVQHRNTQRIMDIIQFMQKCGHSSNIPNEEGQTPLMFAVAADASTTVLRELLKTGSSFKEKDNGENNVLHYALKSRQASAIKFITSNATVREREMMGKTIQTLWEAIDAKQDEATANLMKW 2721

HSP 6 Score: 20.4014 bits (41), Expect = 9.726e-16
Identity = 12/43 (27.91%), Postives = 24/43 (55.81%), Query Frame = 3 
Query: 1962 KGYVRNVNRISAMTENHAKEQTTVNEIEAI-ENLSTFLTTIDL 2087
            KG++R VN+   +  ++AK   +  E++ I E++    T  D+
Sbjct: 2550 KGWMRIVNKAGKIAMDYAKGARSPPEMDRIKESIPMIFTMADV 2592

HSP 7 Score: 50.0618 bits (118), Expect = 3.228e-14
Identity = 24/40 (60.00%), Postives = 30/40 (75.00%), Query Frame = 2 
Query: 1274 LRELMRTGSVLKEKHTGGKTVLAYAMKSKEASAIEFIKPN 1393
            LREL++TGS  KEK  G   VL YA+KS++ASAI+FI  N
Sbjct: 2648 LRELLKTGSSFKEKDNGENNVLHYALKSRQASAIKFITSN 2687

HSP 8 Score: 49.6766 bits (117), Expect = 3.228e-14
Identity = 25/59 (42.37%), Postives = 35/59 (59.32%), Query Frame = 3 
Query: 1458 DTTTASIVKWAGGPDKIKILEVNKFE*NENIFLKKTIKAKRNFPKTIKALLKRSRI*FT 1634
            D  TA+++KW      +K+  VN    N N+ LK+TI A   FPKT+KA+LK   + FT
Sbjct: 2712 DEATANLMKWTYEGSPLKVFNVNYMVRNRNVLLKETIYAHYPFPKTMKAMLKWEGLKFT 2770

HSP 9 Score: 66.2402 bits (160), Expect = 3.496e-10
Identity = 30/83 (36.14%), Postives = 46/83 (55.42%), Query Frame = 1 
Query: 4684 VRIFFQICKGDFDELLEWPLKNKTF-----KSDQRNPCYI-------QPTTEENLAAGGPAFFQQDILRQAAYVKDDNIYIKI 4896
            + +F ++ +GD+DELL WP K         + D RNP          +PTT+ N A G P F+ Q  LR   ++++DN+YIK+
Sbjct: 3743 ISVFVRVGRGDYDELLTWPFKQNMILTMKGQEDYRNPIRTGNEPQMGRPTTDWNTAIGTPRFYPQQRLRGEGFLREDNLYIKL 3825
The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TRAF35.377e-935.56TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF35.952e-935.56TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF35.952e-935.56TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF36.291e-935.56TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF36.291e-935.56TNF receptor associated factor 3 [Source:HGNC Symb... [more]
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
traf37.058e-1034.44TNF receptor-associated factor 3 [Source:ZFIN;Acc:... [more]
traf13.170e-736.26TNF receptor-associated factor 1 [Source:ZFIN;Acc:... [more]
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ssh26.984e-935.56slingshot protein phosphatase 2 [Source:Xenbase;Ac... [more]
ssh27.268e-935.56slingshot protein phosphatase 2 [Source:Xenbase;Ac... [more]
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Traf34.968e-935.56TNF receptor-associated factor 3 [Source:MGI Symbo... [more]
Traf35.119e-935.56TNF receptor-associated factor 3 [Source:MGI Symbo... [more]
Traf35.119e-935.56TNF receptor-associated factor 3 [Source:MGI Symbo... [more]
Traf52.843e-728.26TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
Traf52.843e-728.26TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
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BLAST of TNF receptor-associated factor 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|Q13114|TRAF3_HUMAN2.858e-835.56TNF receptor-associated factor 3 OS=Homo sapiens O... [more]
sp|Q60803|TRAF3_MOUSE3.475e-835.56TNF receptor-associated factor 3 OS=Mus musculus O... [more]
sp|O00463|TRAF5_HUMAN1.834e-630.77TNF receptor-associated factor 5 OS=Homo sapiens O... [more]
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BLAST of TNF receptor-associated factor 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3Q3A2F59.637e-936.59MATH domain-containing protein OS=Kryptolebias mar... [more]
H2YYB21.375e-833.33MATH domain-containing protein OS=Ciona savignyi O... [more]
H2YBM23.505e-831.82MATH domain-containing protein OS=Ciona savignyi O... [more]
A0A3B1IJ189.122e-834.44TNF receptor associated factor 3 OS=Astyanax mexic... [more]
H2YBL72.278e-731.11MATH domain-containing protein OS=Ciona savignyi O... [more]
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSAMXT00000035169.13.455e-1134.44pep primary_assembly:Astyanax_mexicanus-2.0:9:3354... [more]
traf14.498e-937.89TNF receptor-associated factor 1-like [Source:NCBI... [more]
traf15.560e-937.89TNF receptor-associated factor 1-like [Source:NCBI... [more]
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000000074.11.057e-831.11pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-... [more]
ENSPMAT00000002130.14.558e-625.56pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 g... [more]
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO388732.386e-934.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO494641.923e-833.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO495457.575e-735.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of TNF receptor-associated factor 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
traf31.764e-933.33TNF receptor associated factor 3 [Source:NCBI gene... [more]
ENSORLT00000001369.26.199e-632.63TNF receptor-associated factor 5 [Source:NCBI gene... [more]
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BLAST of TNF receptor-associated factor 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000016682.18.859e-2848.72SMESG000016682.1[more]
SMESG000016682.18.930e-2848.72SMESG000016682.1[more]
SMESG000016682.19.004e-2848.72SMESG000016682.1[more]
SMESG000022654.11.161e-2747.44SMESG000022654.1[more]
SMESG000066529.12.631e-2646.15SMESG000066529.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034031 ID=SMED30034031|Name=TNF receptor-associated factor 3|organism=Schmidtea mediterranea sexual|type=transcript|length=6618bp
TGATGAGTATCTTAAAAAGAATTGTAATGACTGGCGTAGCACACCGATTT
CAAATTGCTCAAATCATATAAAACAAGTAAAAATGAAGAAATTATGATCA
ATGCTCTGATGGATAATTATGCCTCCAATCCTATATCGGATGTTTCAGAA
ACTGTTATTATCGACGACTCGAATTCGGATTCTGAAAATAAATATGCAAT
CCTTAAAGAATCAAAAGGATCGACAAAAAAAGCTGCTAATAAACTACTAC
AGAAACAAATTCTTGGTGATGTTTTTGAAGCGGCATTGGGAATTCCCAGA
TTTGTTCTAAAATCCTGGTGTCTTTCAGCCTGTCTAGATCAATGTTTAGG
CCAATTTCTATCTGGATGGATAAATAGAGCCATTGAATTAAACTTATCAA
GGGTAATTCAAATATTAGTGAGATTGTCTTTATTTCAGAAGTGTTAGTAT
GATTTTCGATCCCTGTCCTTGATGGCCTCTTTCAGTTTTAGTTTAGTGTT
TTCCTTCTCTAAAATTCTCATTTTCTGCTTCATTTCTTCATATTGTTTCT
TAAACATCTCATTATGTTGCTTCAGCTTTTTTGTCTGCGTGGTTTAGTCC
ACGTTTCTTCCATTTTTCGACAGTTTCTTATTAGCGATTTGGCTCTGCGA
CTGCTGATGAGCCTCTCTACGATAACGAACTACATCTTGCTTAAAACGCT
TGATCTCTGTTGTTGGGGTACATCGAAAAAAAGCATTTAATCGTCCAATT
AACAAAAGAAATAATGGGTCAAAGATAAAAACTTTTTCGATATACTAGGT
GGAATTACGCTAATGATGAAAGATTATTCAAGGGGTAAAAGTAAACCAAC
CAAAATTACTACCATAATAGAAAGAATACCAGTTTTATTTACCATTACAG
ATTTAAATAAAAAAATAAATCACGTACTAATAACCAAAAACGAAATGCGA
ATACTAGAAATATGAATATAATGGAAGTGTGTGGACAAAACACGAATATT
AGTAACTCGAAAGGGCAGATACGATTAATGATTGCTATTGGTATAGATCA
GGCCTGTATAAAGTGTGGCTCTTAAGCCACGTATGGCTCTTTAGGTTTAT
TTCGTGGCTCTCAACATAAATCTGAATTAAGAATGTCGTGGCTCTTATAA
AAACCGAAATTTCATAGAAAAAAAGGCAAATTACATATTTAGTTAGAAAT
GGGTTTCATAATTAAAAATGGCATGAAAGCATGCAATTTTTACATAATGA
GAAAAATAAAGTGGAATTTAACTCTCAGAGAATTAATGAGAACCGGTTCA
GTTCTAAAAGAAAAACATACCGGAGGTAAGACAGTTCTCGCCTATGCGAT
GAAGTCAAAAGAAGCAAGCGCCATAGAATTTATTAAACCAAACGACAAAA
AGGATATTAAAGCTATATGACCAAAAGAAAAACTAATAATTGATGCGATA
TCTATAAGACACGACCACTGCATCAATAGTAAAATGGGCAGGAGGACCTG
ACAAAATAAAAATTCTAGAGGTAAATAAATTCGAATAAAACGAAAATATA
TTCCTTAAGAAAACAATTAAAGCGAAACGAAATTTTCCGAAAACTATAAA
AGCATTATTAAAAAGAAGTAGGATATGATTTACCGGTATCAAAAATGAAA
GAGAGAATGGTACCAAGGAAGGAAGAACTAGAAAATCAAGTGCGAAATTG
CCAATGAAAGATAGAATAGCAATCATAACGACAGAGATGATAAAGATGAC
AACAAAGGTAAAAGATATAACGAAATCGGCAAGAGGCGAGATCCAGAAAC
AAGTCACACTACAACCAAACCTTTAGACAAATATAGAATATTAGAATCAA
AGGATACAAAGAAAAAAGCTGAGGAGAAATCAAAGCAAACATTGCCAAAG
AACGACCTTCAGGAATATTGGAATTAATAGCAAGAGAAATATCGCCCGTA
TGGTTTAAAGAAAAGGATATGTTCGAAACGTTAACCGAATATCGGCCATG
ACGGAAAATCATGCAAAAGAACAAACAACAGTCAATGAAATAGAAGCAAT
AGAAAACCTATCAACGTTTCTTACAACCATCGATCTTAAAATAATACACT
ATTGCATAGAGTACTAAAAGGAAATTATAGAGAACGAATAATATAAACAC
TCAAAGCCATGGAAGATTACAAACAACACACTAACGTTAAAAGCAATGAA
GGACAAACTCCATTAATGATAGCAGTAGCAGGATATGTATCAACCACAGT
CCTTAGAAAATGAATAGAAAATGGCTCGTTATTAAGAGAAGATAACAGAA
GTAGAAACGTGCTAATCTACGATATGAAATCAAGATTTGCAACAAAATTT
ATCATTAATAACGCCGCCAAAAAAGATACCTATGTACTATGTCGAACAAG
TAGACCACTAAAAGAAGCAATAGAGAAAGGCCAAGACGAAACATCAAAAG
CCATAATCGAATGGAAAATAAGTGAATTGGATCTGGAAAAGAGAAGCTAA
AAGAATTAGTACGAATCTGGCATAAGAAACTTAAAAAATGCACCGGGAAA
ATTTGGGAAATAGACGAAATAAGGAGCAACAAGGTTAAAATAATTCAGCT
ATATATGTAAATTATTAAAATAATAAAGGTCGAGGACGACATTTCTGATG
GAATCCCGAGTAATGACAAAGAGAATGAAGACAGAAAATATAAAACTAAT
AACGAAAGTCGAAAACATAGCAATCAACAATCAAAACCAAAGAATCAAAA
GATGAATACAACTAGTAAAAATGATGAAAACCAGACGATAAAACTGCAAA
AGAATCAATTCCAACTCTGGATAAAAAACATCCATTATCAAGACATCACA
AGAGTGGCCAAACAAAATCGACGTATATAAAATAACAAATAAGAGATGGG
GATATACGAACGCTGCGTATAGAGCCCCCAGAGATAATGATATGATGAAA
GAAAGAAACGGTGTAAATAATGTATAAAAGTATGATAAAGTTTGTGTTGT
GTAAAAAGTGGATAATGTGTAAATAATATAAAGTAGTTTACTGTATGATA
CCGGACAAATTAAACTAGTAATTAACAATACGATGCAATAACAAATAGTA
AAACTTTAAGAAGCCAGAAAATATTGTAAATTATCATTATTAGAAAATTG
ATCTATCCAGGAGAAATCAAATTAATCAAGCCGAAGTACCACCCTTCGTT
GAAACCATGAACCCAAGTTCAACTCACCCGAATTCCCCGCAGAAATCGTA
TGGAATATTATCTACCACCCTAATGAACAACCATCAAAATCCAATGTAAT
TAATAGAATAACAAACCAAGCCTGAGAACAATGGATGCAATCACAAGCAC
TATTATCAGAAAGCGTTAAACGAAATATAATGTATATAATATTAATCGAA
CAACAACAAATAATCGCACAACTATAACAACAAAACTACCTACAAACCTG
TGATATCATGAAATTACAAATAAGTCCAACGGAAGAAATTTTAGAATAAT
ACGACCAAATGAGAGACCTCCCGGAAGAATCAGATTCAGGGGAAGAAAAT
ACATAAATCAATAAATTAGTTGTAAATAAAATTGTAAATGAAATATACGA
TTTATGTAAAAAGAAAAATTGTCAATAATAGATATTATTCCAGAAAATTA
GAATGCAAGCATCAATTAATCATATCCAACGAAAACCCGAAGACGAACCC
CAAATAAACCTTATGATTCGGTTATATCCAGCAAGATCACACGAATTTGA
AGAAAGATTCATGTGCTGCGAGTGTAAAAAGTTGTTAATAGAAGCGAGTC
AAACCGAATGATGATGCTGAATATGTAGATAGTGGGCAATCAAAGTAATC
AGAAAAGAATTAAAACTGCCCAGATTGGGAAAAACAACAATTAAAACCCT
AGAAAATACGAGACCTGATCATGCAGCGAATCACTAAATATCCAATCTAC
TAGTCAAATGTCTAAAAAACTGGCTTTTAAAAAGAAACCACTAATCACCA
AGAAGTATATGAATTGATTGAAGTAAAATGTAAAAAGTGTAATGATACAA
TTACCCCAAAATAGAGTAAGTCATCCAAAGATATGTGAAATGAACGAAGA
CAAATGCGAATTATGTGGAGAAATCGACATTTGGAAGGAATTAGAAACAA
CACTTTAAAATTTAATCGAAAGACAAATATGCGACGAATACAAAAATAAA
TGTCCAAATTAATTTAATATGAAAGAAAGTGTCACATTAACAGAACACTG
GGAAACCTGTTCACGAAAGGCAATAATGTGTCCACTAAAACTATTAAATT
GTAAAATACCAACCTCTTGAGAAAAGATGTCAAGCATCTGAAAGAAAATA
ATGTAGAACATCTAACTACAATGATAGAAGCAATCGAAATAACGGCAATG
TCTATAAACGATTCGAAAGATAATCTAAAATCACACATAGTATTGATCAA
GGAAATGTTAAATGCAAGGGAATACTTTAAAAAACTGGAAGAACAGATGA
TACAGAAAACGATATTAATAGACCGAAAGCTAAAAGAAATCACCATCCAA
CAAAAAAAATGCGAAGCGAATATGCCAACATCAGAAGAACTAACAATTAC
ACCTTATGTACGGATGGACCAAGAAACTGAAACGAGCTAAACAGGAAACG
CATGTATATTGATATTGAGTCCACAATTTTGTAGTTAGAATATTCTTCCA
GATATGCAAAGGTGATTTCGATGAATTACTAGAATGGCCTTTAAAAAACA
AAACATTCAAATCCGATCAGCGAAACCCATGCTATATACAACCCACAACC
GAAGAGAATCTAGCAGCCGGAGGACCAGCATTCTTCCAACAAGATATTTT
GAGACAAGCCGCATACGTAAAAGATGATAATATCTACATAAAAATAAATG
TAATAAAAGATTATAAATCGACTTGATTAATGAAGAGAGACGTGTATAAA
TGTATAAAGATCGGTGGGAGTGTAAAAAAACTAAATTAGAAAATCAATAA
AAAAATGTGTCGTATTCAAAAATTATAAAACAAAAAAATCAGAAAACTAA
AAATAAATAAATATCGGAAAATCAAAACTATGAAGTCCAAAGAAATATTA
ATGAGAATTTATTATTAGAAATGGAAAATATAATTAAAAAGAACGAGAAA
AAGAATTAAGAAATAAAATTCGAAATATTAAAAAGTATAACGAATTCAGA
CCTCCCAAATACGAAATACAATCCAAAGAAGGAACAGGAACAAGAAAGGA
CCCCAGTCAAATGGGAGACAAATATCATTTGCAATACAAAAAGCATTTAC
TGAGAAACAGAGCAGAGGGTTAGTGAAAGATGGATTCTATTTTACGGTCA
CATTTGTCTATTGCGACGGATATAAAAAATTGCAATGATATTAAAACCAC
AATTTTTGTTTACCAAGATGCCCATTTCTAATGAACCTCAAAACCAGCCA
TCAAACAGATACAGTTTAAAGAATTATTCGAAAGAAAATCGCCCAAAGAC
AAAGAGCAAAAATGTCAATCGTGTAATCGATTGAGGACAAATAAACCAAG
TCAAAACGTTTTTAATAATAGAGTAACAACCTTCATAAACTAAAACCTTG
CCTTACCATTTGTAATACAATGATTTTAATCAAACGGCAAACGAAACTTA
GAATGTGGGATTGAATACATATTGACAAAAGAAACACGAACATTGGATCA
TCTGGAAGATTCTGTTTTCAATATAGCCTTAACTGAAAAGGAACAGAAAC
CACTGATAGACGAAATCAGAGCAATCATTAAACAGTCAGAGAATCAATTA
AAACAACCGGTTATCATAATAGATTCACCAAAATGATATTGAGAAAGAGG
TTAAGTAGAAGCGTACAAGCCAATGAATCAATATTTAAATTAATCAAAGT
AACACAATACGCAGAAAAACATCAATATGAACTGGGTGAATCAAGTGCTA
TAAAAGTAATATTTTGCGAACACAGTTGCACTATATGTTGGATAAAAAAT
TTAGAGGTGATTCATCTTTCTTGTGGACACTTGCAAAGAATGCAGCCAAT
GATTATTACAATTTTCAATATGTAGACAACTGATTTTCATCATTAGTGAT
CCGCATAATCAGTACTATCACTGTAAAAGTTGGAATAATTATCAACTTGA
TCATCGAAAGTTTCTTCTTTTATTTCAATGGAGACATTCACTATCTCGGT
TACTTCTATCTCTTCCAGAATTAGTCTTTTGCCTCCATATTCTACGCGTC
TTGAACTTCCAATTCCTTTTGCATGTCTTGAATATTTGGTTTAGATTGGT
TCCTCTTCTTGAATTTAATCTTTATCATGCGAATCAAGTATCTCAATTGT
TTCGACTTGTTATTTATCTTCCGAGTCTATTATTTCAATAATCTTTGGAA
TTTCTTCAATGACTTTGTTTTTATTCGAGTTTTTTTAATATTTTGTAATA
ATTGTGTTGAAGCTTTTCTTTAGAAAATTGTGTCTGTGTATTACAAATTA
ATTCAAATGACCTAAAGGAAAACTTTGATACTTTTCGCTAAAATAACTAT
GAGAAATACAAAGGTCTTGCTCTTCAAATTGGCGATGCCTTCAAATGCTC
CACTTCTATCTCAGCTTT
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protein sequence of SMED30034031-orf-1

>SMED30034031-orf-1 ID=SMED30034031-orf-1|Name=SMED30034031-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=118bp
MINALMDNYASNPISDVSETVIIDDSNSDSENKYAILKESKGSTKKAANK
LLQKQILGDVFEAALGIPRFVLKSWCLSACLDQCLGQFLSGWINRAIELN
LSRVIQILVRLSLFQKC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0005515protein binding
GO:0004842ubiquitin-protein transferase activity
GO:0005164tumor necrosis factor receptor binding
GO:0008270zinc ion binding
GO:0016740transferase activity
GO:0019901protein kinase binding
GO:0019903protein phosphatase binding
GO:0031625ubiquitin protein ligase binding
GO:0031996thioesterase binding
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005768endosome
GO:0009898cytoplasmic side of plasma membrane
GO:0035631CD40 receptor complex
Vocabulary: INTERPRO
TermDefinition
IPR008974TRAF-like
Vocabulary: biological process
TermDefinition
GO:0001817regulation of cytokine production
GO:0002224toll-like receptor signaling pathway
GO:0002376immune system process
GO:0006915apoptotic process
GO:0007165signal transduction
GO:0008063Toll signaling pathway
GO:0016567protein ubiquitination
GO:0030162regulation of proteolysis
GO:0032088negative regulation of NF-kappaB transcription factor activity
GO:0032648regulation of interferon-beta production
GO:0033209tumor necrosis factor-mediated signaling pathway
GO:0042981regulation of apoptotic process
GO:0045087innate immune response
GO:0050688regulation of defense response to virus