Pancreas transcription factor 1 subunit alpha
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30034009 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Human
Match: PTF1A (pancreas associated transcription factor 1a [Source:HGNC Symbol;Acc:HGNC:23734]) HSP 1 Score: 105.531 bits (262), Expect = 8.786e-27 Identity = 48/63 (76.19%), Postives = 56/63 (88.89%), Query Frame = 3 Query: 150 KLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 +L + RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 160 ELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 222
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Human
Match: FERD3L (Fer3 like bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:16660]) HSP 1 Score: 75.0998 bits (183), Expect = 1.649e-16 Identity = 34/63 (53.97%), Postives = 52/63 (82.54%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEE 350 QRQAAN+RERKRM ++N+AF++LR +PT YEKRLS+++TLR+AI YI+F+ +++ + +E Sbjct: 102 QRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLESCEKKE 164
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Human
Match: TWIST1 (twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428]) HSP 1 Score: 67.781 bits (164), Expect = 4.095e-14 Identity = 34/65 (52.31%), Postives = 48/65 (73.85%), Query Frame = 3 Query: 147 EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQ 341 E+L QR AN+RER+R QS+N+AF LR IPT+P +K LSK+ TL++A YI+FL ++Q D+ Sbjct: 37 EELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDFLYQVLQSDE 100
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Human
Match: TCF15 (transcription factor 15 [Source:HGNC Symbol;Acc:HGNC:11627]) HSP 1 Score: 67.781 bits (164), Expect = 1.407e-13 Identity = 33/75 (44.00%), Postives = 45/75 (60.00%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIM----QVDQGEEIYEKTFIA 374 QRQAAN RER R QS+N AF LR IPT P +++LSK++T+R+A YI L ++ D G+ + A Sbjct: 73 QRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETVRLASSYIAHLANVLLLGDSADDGQPCFRAAGSA 147
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Human
Match: TWIST1 (twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428]) HSP 1 Score: 67.781 bits (164), Expect = 1.555e-13 Identity = 34/65 (52.31%), Postives = 48/65 (73.85%), Query Frame = 3 Query: 147 EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQ 341 E+L QR AN+RER+R QS+N+AF LR IPT+P +K LSK+ TL++A YI+FL ++Q D+ Sbjct: 104 EELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDFLYQVLQSDE 167
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Celegans
Match: hlh-13 (Helix-loop-helix protein 13 [Source:UniProtKB/Swiss-Prot;Acc:Q20561]) HSP 1 Score: 80.8777 bits (198), Expect = 2.123e-19 Identity = 44/88 (50.00%), Postives = 58/88 (65.91%), Query Frame = 3 Query: 117 DSRFSRSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQV--DQGEEIYEKTFIA 374 DS + C E +RQ A++RERKRM SIN AF +LR +IPT PYEKRLSK+DTL +AI YIN L +++ D G+ I + +A Sbjct: 29 DSSYDSYYCEEP--EERQTASIRERKRMCSINVAFIELRNYIPTFPYEKRLSKIDTLNLAIAYINMLDDVLRTPEDSGQYIQKCVHMA 114
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Celegans
Match: hlh-15 (Helix Loop Helix [Source:UniProtKB/TrEMBL;Acc:Q18590]) HSP 1 Score: 60.4622 bits (145), Expect = 3.546e-12 Identity = 26/50 (52.00%), Postives = 38/50 (76.00%), Query Frame = 3 Query: 183 RERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQ 332 RER R++S N AF +LR +PT+P EK+LSK++ LR +I YI+FL ++Q Sbjct: 40 RERIRVESFNMAFSQLRALLPTLPVEKKLSKIEILRFSIAYISFLDNLLQ 89
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Celegans
Match: ngn-1 (NeuroGeNin [Source:UniProtKB/TrEMBL;Acc:Q95XG7]) HSP 1 Score: 58.9214 bits (141), Expect = 7.978e-11 Identity = 45/135 (33.33%), Postives = 62/135 (45.93%), Query Frame = 3 Query: 105 RKNSDSRFSRSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFL-----GGIMQVDQGEEIYEKTFIANDQ------FQTESNLKSSHLPYSFANSESNYIDYYGWAH 476 RK S + R+K +R AN RER+RM S+NDA E LR +P +P E +++K++TLR A YI L GG Q E + Q FQ+ + P S++N S YY H Sbjct: 49 RKRSPATIERAK-----TVRRDKANARERRRMNSLNDALEHLRGILPALPDEPKMTKIETLRKAQEYIASLSFQLSGGSPDSSQCCETGSCGLCSASQSLQSTPFQSPCFPQPLQYPSSYSNPPSQM--YYHHHH 176
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Celegans
Match: hlh-8 (Twist-related protein [Source:UniProtKB/Swiss-Prot;Acc:Q11094]) HSP 1 Score: 58.151 bits (139), Expect = 1.478e-10 Identity = 29/54 (53.70%), Postives = 39/54 (72.22%), Query Frame = 3 Query: 156 ARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFL 317 +QR AN RER+R + +NDAF LR IP+MP +K +SK+ TLR+A YI+FL Sbjct: 19 VQQRACANRRERQRTKELNDAFTLLRKLIPSMPSDK-MSKIHTLRIATDYISFL 71
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Celegans
Match: hlh-6 (Helix-loop-helix protein 6 [Source:UniProtKB/Swiss-Prot;Acc:Q10007]) HSP 1 Score: 59.3066 bits (142), Expect = 1.651e-10 Identity = 32/74 (43.24%), Postives = 48/74 (64.86%), Query Frame = 3 Query: 177 NMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTES 398 N RER R++++ND +E+LR H+P EKR+SKVDTLR+AI YI L +++ E+++ + FQ ES Sbjct: 179 NERERCRVRNVNDGYERLRKHLPVHFDEKRISKVDTLRLAIRYIKHLDNLLR----SELHQYNCKCFNGFQEES 248
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Fly
Match: Fer1 (gene:FBgn0037475 transcript:FBtr0081567) HSP 1 Score: 105.916 bits (263), Expect = 8.341e-28 Identity = 47/70 (67.14%), Postives = 60/70 (85.71%), Query Frame = 3 Query: 132 RSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQ 341 R KC ++A+QRQAAN+RER+RMQSIN+AFE LR HIPT+PYEKRLSKVDTL++AI YI FL +++ D+ Sbjct: 72 RLKCASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMVKKDK 141
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Fly
Match: Fer1 (gene:FBgn0037475 transcript:FBtr0334670) HSP 1 Score: 105.916 bits (263), Expect = 9.775e-28 Identity = 47/70 (67.14%), Postives = 60/70 (85.71%), Query Frame = 3 Query: 132 RSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQ 341 R KC ++A+QRQAAN+RER+RMQSIN+AFE LR HIPT+PYEKRLSKVDTL++AI YI FL +++ D+ Sbjct: 77 RLKCASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMVKKDK 146
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Fly
Match: Fer2 (gene:FBgn0038402 transcript:FBtr0301709) HSP 1 Score: 91.2781 bits (225), Expect = 4.585e-22 Identity = 46/87 (52.87%), Postives = 61/87 (70.11%), Query Frame = 3 Query: 162 QRQAANMRERKRMQS-INDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHL 419 QRQAAN+RERKR+QS IN AF++LRVH+PT PYEKRLSK+DTLR+AI YI+ L ++Q D Y + + + +N +S L Sbjct: 148 QRQAANVRERKRIQSSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVLQTDYDPLTYVEKCLRGEIKADRANWNTSDL 234
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Fly
Match: Fer2 (gene:FBgn0038402 transcript:FBtr0344012) HSP 1 Score: 90.8929 bits (224), Expect = 5.727e-22 Identity = 49/88 (55.68%), Postives = 62/88 (70.45%), Query Frame = 3 Query: 162 QRQAANMRERKRMQS-INDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIY-EKTF---IANDQFQTESNLKS 410 QRQAAN+RERKR+QS IN AF++LRVH+PT PYEKRLSK+DTLR+AI YI+ L ++Q D Y EK I D+ +NL + Sbjct: 148 QRQAANVRERKRIQSSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVLQTDYDPLTYVEKCLRGEIKADRANWNTNLTA 235
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Fly
Match: Fer2 (gene:FBgn0038402 transcript:FBtr0344010) HSP 1 Score: 88.9669 bits (219), Expect = 2.890e-21 Identity = 46/92 (50.00%), Postives = 61/92 (66.30%), Query Frame = 3 Query: 162 QRQAANMRERKRMQ------SINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHL 419 QRQAAN+RERKR+Q SIN AF++LRVH+PT PYEKRLSK+DTLR+AI YI+ L ++Q D Y + + + +N +S L Sbjct: 148 QRQAANVRERKRIQRSAPTGSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVLQTDYDPLTYVEKCLRGEIKADRANWNTSDL 239
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Zebrafish
Match: ptf1a (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:368662]) HSP 1 Score: 103.219 bits (256), Expect = 1.302e-26 Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 3 Query: 165 RQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 117 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELVQSD 174
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Zebrafish
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410]) HSP 1 Score: 88.9669 bits (219), Expect = 4.513e-22 Identity = 40/56 (71.43%), Postives = 46/56 (82.14%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIM 329 QR AAN+RERKRM SIN AFE+LR H+PT PYEKRLSK+DTLR+AI YI L I+ Sbjct: 66 QRHAANIRERKRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLREIL 121
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Zebrafish
Match: ferd3l (Fer3-like bHLH transcription factor [Source:ZFIN;Acc:ZDB-GENE-081104-461]) HSP 1 Score: 78.9518 bits (193), Expect = 4.104e-19 Identity = 35/57 (61.40%), Postives = 48/57 (84.21%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQ 332 QRQAAN+RERKRM S+N+AF++LR +PT YEKRLS+++TLR+AI YI F+ I++ Sbjct: 25 QRQAANIRERKRMFSLNEAFDRLRRRVPTFAYEKRLSRIETLRLAIVYIAFMTDILE 81
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Zebrafish
Match: tcf15 (transcription factor 15 [Source:ZFIN;Acc:ZDB-GENE-980605-20]) HSP 1 Score: 73.1738 bits (178), Expect = 7.691e-16 Identity = 37/94 (39.36%), Postives = 53/94 (56.38%), Query Frame = 3 Query: 153 LARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFA 434 + +QR AAN RER R QS+N AF LR IPT P +++LSK++TLR+A YI+ L ++ + G E + A Q +S K +F Sbjct: 62 IVKQRNAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVLLIGDGGEDAQPCVSAVYSAQGDSGGKQPRTICTFC 155
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Zebrafish
Match: si:ch211-246m6.4 (si:ch211-246m6.4 [Source:ZFIN;Acc:ZDB-GENE-050208-498]) HSP 1 Score: 73.1738 bits (178), Expect = 7.729e-16 Identity = 35/86 (40.70%), Postives = 55/86 (63.95%), Query Frame = 3 Query: 153 LARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKS 410 +++QRQAAN RER R S+N AF LR IPT P +++LSK++TLR+A YI+ L ++ + + + ++ Q+ +NLKS Sbjct: 81 VSKQRQAANARERDRTHSVNTAFTSLRTLIPTEPADRKLSKIETLRLASSYISHLANVLLLGEDCRDGQPCLKYHNILQSNANLKS 166
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Xenopus
Match: PTF1A (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:100494161]) HSP 1 Score: 102.834 bits (255), Expect = 7.199e-26 Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 3 Query: 165 RQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 171 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQSD 228
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Xenopus
Match: ENSXETT00000031930.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:9:55646956:55647657:1 gene:ENSXETG00000008961.1 transcript:ENSXETT00000031930.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 86.6557 bits (213), Expect = 5.254e-21 Identity = 40/70 (57.14%), Postives = 50/70 (71.43%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFI 371 RQAAN+RER+RM SIN AFE+LR +PT PYEKRLSK+DTLR+AI YI L I+ + Y + F+ Sbjct: 84 HRQAANIRERRRMLSINSAFEELRGRVPTFPYEKRLSKIDTLRLAIAYIALLSDILSSGMDPKTYVEEFV 153
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Xenopus
Match: tcf15 (transcription factor 15 [Source:NCBI gene;Acc:549260]) HSP 1 Score: 74.3294 bits (181), Expect = 2.149e-16 Identity = 33/74 (44.59%), Postives = 50/74 (67.57%), Query Frame = 3 Query: 147 EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTF 368 + + +QRQAAN RER R QS+N AF LR IPT P +++LSK++TLR+A YI+ L ++ + +G + + F Sbjct: 58 QPVVKQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVLLLGEGCQDGQPCF 131
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Xenopus
Match: ferd3l (Fer3-like bHLH transcription factor [Source:NCBI gene;Acc:100124312]) HSP 1 Score: 73.1738 bits (178), Expect = 2.441e-16 Identity = 33/57 (57.89%), Postives = 48/57 (84.21%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQ 332 QRQAAN+RERKRM ++N+AF+ LR +PT YEKRLS+++TLR+AI YI+F+ +++ Sbjct: 66 QRQAANIRERKRMFNLNEAFDLLRKKVPTFAYEKRLSRIETLRLAIVYISFMTEMLK 122
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Xenopus
Match: hnrnpc (heterogeneous nuclear ribonucleoprotein C (C1/C2) [Source:Xenbase;Acc:XB-GENE-489141]) HSP 1 Score: 74.3294 bits (181), Expect = 3.913e-16 Identity = 33/74 (44.59%), Postives = 50/74 (67.57%), Query Frame = 3 Query: 147 EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTF 368 + + +QRQAAN RER R QS+N AF LR IPT P +++LSK++TLR+A YI+ L ++ + +G + + F Sbjct: 58 QPVVKQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYISHLANVLLLGEGCQDGQPCF 131
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Mouse
Match: Ptf1a (pancreas specific transcription factor, 1a [Source:MGI Symbol;Acc:MGI:1328312]) HSP 1 Score: 105.531 bits (262), Expect = 6.615e-27 Identity = 48/63 (76.19%), Postives = 56/63 (88.89%), Query Frame = 3 Query: 150 KLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 +L + RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 157 ELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 219
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Mouse
Match: Ferd3l (Fer3 like bHLH transcription factor [Source:MGI Symbol;Acc:MGI:2150010]) HSP 1 Score: 76.2554 bits (186), Expect = 3.427e-17 Identity = 35/63 (55.56%), Postives = 52/63 (82.54%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEE 350 QRQAAN+RERKRM ++N+AF++LR +PT YEKRLS+++TLR+AI YI+F+ ++Q + +E Sbjct: 104 QRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLQSKEEKE 166
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Mouse
Match: Tcf15 (transcription factor 15 [Source:MGI Symbol;Acc:MGI:104664]) HSP 1 Score: 76.6406 bits (187), Expect = 4.240e-17 Identity = 41/115 (35.65%), Postives = 57/115 (49.57%), Query Frame = 3 Query: 93 KNFPRKNSDSRFSRSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFAN 437 + P S R S P + RQRQAAN RER R QS+N AF LR IPT P +++LSK++TLR+A YI L ++ + + + F A ++ P S Sbjct: 48 RRGPGPGSGRRASNGAGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGDAADDGQPCFRAAGGGKSAVPAADGRQPRSICT 162
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Mouse
Match: Twist2 (twist basic helix-loop-helix transcription factor 2 [Source:MGI Symbol;Acc:MGI:104685]) HSP 1 Score: 66.6254 bits (161), Expect = 1.169e-13 Identity = 34/65 (52.31%), Postives = 48/65 (73.85%), Query Frame = 3 Query: 147 EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQ 341 E+L QR AN+RER+R QS+N+AF LR IPT+P +K LSK+ TL++A YI+FL ++Q D+ Sbjct: 62 EELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDFLYQVLQSDE 125
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Mouse
Match: Twist2 (twist basic helix-loop-helix transcription factor 2 [Source:MGI Symbol;Acc:MGI:104685]) HSP 1 Score: 66.6254 bits (161), Expect = 1.169e-13 Identity = 34/65 (52.31%), Postives = 48/65 (73.85%), Query Frame = 3 Query: 147 EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQ 341 E+L QR AN+RER+R QS+N+AF LR IPT+P +K LSK+ TL++A YI+FL ++Q D+ Sbjct: 62 EELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDFLYQVLQSDE 125
BLAST of Pancreas transcription factor 1 subunit alpha vs. UniProt/SwissProt
Match: sp|Q7RTS3|PTF1A_HUMAN (Pancreas transcription factor 1 subunit alpha OS=Homo sapiens OX=9606 GN=PTF1A PE=1 SV=1) HSP 1 Score: 105.531 bits (262), Expect = 4.219e-26 Identity = 48/63 (76.19%), Postives = 56/63 (88.89%), Query Frame = 3 Query: 150 KLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 +L + RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 160 ELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 222
BLAST of Pancreas transcription factor 1 subunit alpha vs. UniProt/SwissProt
Match: sp|Q9QX98|PTF1A_MOUSE (Pancreas transcription factor 1 subunit alpha OS=Mus musculus OX=10090 GN=Ptf1a PE=1 SV=1) HSP 1 Score: 105.531 bits (262), Expect = 4.627e-26 Identity = 48/63 (76.19%), Postives = 56/63 (88.89%), Query Frame = 3 Query: 150 KLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 +L + RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 157 ELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 219
BLAST of Pancreas transcription factor 1 subunit alpha vs. UniProt/SwissProt
Match: sp|Q64305|PTF1A_RAT (Pancreas transcription factor 1 subunit alpha OS=Rattus norvegicus OX=10116 GN=Ptf1a PE=1 SV=1) HSP 1 Score: 105.531 bits (262), Expect = 5.032e-26 Identity = 48/63 (76.19%), Postives = 56/63 (88.89%), Query Frame = 3 Query: 150 KLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 +L + RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 159 ELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 221
BLAST of Pancreas transcription factor 1 subunit alpha vs. UniProt/SwissProt
Match: sp|Q7ZSX3|PTF1A_DANRE (Pancreas transcription factor 1 subunit alpha OS=Danio rerio OX=7955 GN=ptf1a PE=2 SV=1) HSP 1 Score: 103.219 bits (256), Expect = 9.829e-26 Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 3 Query: 165 RQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 117 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELVQSD 174
BLAST of Pancreas transcription factor 1 subunit alpha vs. UniProt/SwissProt
Match: sp|Q4ZHW1|PTF1A_XENLA (Pancreas transcription factor 1 subunit alpha OS=Xenopus laevis OX=8355 GN=ptf1a PE=2 SV=1) HSP 1 Score: 102.834 bits (255), Expect = 1.705e-25 Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 3 Query: 165 RQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 121 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSEMVQSD 178
BLAST of Pancreas transcription factor 1 subunit alpha vs. TrEMBL
Match: U5YR63 (Ptf-1 protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=ptf-1 PE=2 SV=1) HSP 1 Score: 184.882 bits (468), Expect = 2.582e-57 Identity = 87/88 (98.86%), Postives = 87/88 (98.86%), Query Frame = 3 Query: 171 AANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFA 434 AANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYS A Sbjct: 1 AANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSLA 88
BLAST of Pancreas transcription factor 1 subunit alpha vs. TrEMBL
Match: A0A194PER3 (Pancreas transcription factor 1 subunit alpha OS=Papilio xuthus OX=66420 GN=RR46_08277 PE=4 SV=1) HSP 1 Score: 113.62 bits (283), Expect = 3.870e-28 Identity = 63/116 (54.31%), Postives = 78/116 (67.24%), Query Frame = 3 Query: 102 PRKNSDSRF---SRSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD--------------QGEEIYEKTFIANDQFQTES 398 PRK SD R RS+CP++ +QRQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTL++AIGYI+FLG +++ D Q +E +K I FQ S Sbjct: 17 PRKRSDCRRLHKRRSRCPQQQMQQRQAANLRERRRMQSINDAFEGLRAHIPTLPYEKRLSKVDTLKLAIGYISFLGELVRTDRSISDTMLSGVGNVQNKEEQKKVIIRGSNFQAHS 132
BLAST of Pancreas transcription factor 1 subunit alpha vs. TrEMBL
Match: A0A194QVL7 (Pancreas transcription factor 1 subunit alpha OS=Papilio machaon OX=76193 GN=RR48_15151 PE=4 SV=1) HSP 1 Score: 112.464 bits (280), Expect = 1.260e-27 Identity = 59/101 (58.42%), Postives = 76/101 (75.25%), Query Frame = 3 Query: 102 PRKNSDSRF---SRSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTE 395 PRK SD R RS+CP++ +QRQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTL++AIGYI+FLG +++ D+ + + N Q + E Sbjct: 56 PRKRSDCRRLHKRRSRCPQQQMQQRQAANLRERRRMQSINDAFEGLRAHIPTLPYEKRLSKVDTLKLAIGYISFLGELVRTDRSISDTMLSGVGNVQNKEE 156
BLAST of Pancreas transcription factor 1 subunit alpha vs. TrEMBL
Match: A0A1D2MGL8 (Pancreas transcription factor 1 subunit alpha OS=Orchesella cincta OX=48709 GN=Ocin01_14548 PE=4 SV=1) HSP 1 Score: 111.309 bits (277), Expect = 1.517e-27 Identity = 53/70 (75.71%), Postives = 62/70 (88.57%), Query Frame = 3 Query: 141 CPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEE 350 CP++ +QRQAANMRERKRMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL +++ D+G E Sbjct: 64 CPQQQIQQRQAANMRERKRMQSINDAFEGLRAHIPTLPYEKRLSKVDTLRLAIGYINFLSEVVKTDRGAE 133
BLAST of Pancreas transcription factor 1 subunit alpha vs. TrEMBL
Match: A0A3S2N3E9 (BHLH domain-containing protein (Fragment) OS=Chilo suppressalis OX=168631 GN=evm_014892 PE=4 SV=1) HSP 1 Score: 110.538 bits (275), Expect = 5.212e-27 Identity = 55/84 (65.48%), Postives = 70/84 (83.33%), Query Frame = 3 Query: 102 PRKNSDSRF---SRSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQG 344 P + SD R RS+CP++ +QRQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTL++AIGYI+FLG +++ D+G Sbjct: 66 PVRQSDCRRLHKRRSRCPQQQIQQRQAANLRERRRMQSINDAFEGLRAHIPTLPYEKRLSKVDTLKLAIGYISFLGELVRTDRG 149
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Cavefish
Match: ptf1a (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:103046795]) HSP 1 Score: 104.375 bits (259), Expect = 3.234e-27 Identity = 47/58 (81.03%), Postives = 53/58 (91.38%), Query Frame = 3 Query: 165 RQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 94 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELVQSD 151
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Cavefish
Match: si:dkey-34f9.3 (neurogenic differentiation factor 1-like [Source:NCBI gene;Acc:107197807]) HSP 1 Score: 88.1965 bits (217), Expect = 2.343e-21 Identity = 40/56 (71.43%), Postives = 46/56 (82.14%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIM 329 QR AAN+RERKRM SIN AFE+LR H+PT PYEKRLSK+DTLR+AI YI L I+ Sbjct: 121 QRHAANIRERKRMLSINSAFEQLRCHVPTFPYEKRLSKIDTLRLAIAYIALLREIL 176
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Cavefish
Match: ferd3l (Fer3-like bHLH transcription factor [Source:ZFIN;Acc:ZDB-GENE-081104-461]) HSP 1 Score: 76.6406 bits (187), Expect = 1.687e-18 Identity = 34/52 (65.38%), Postives = 46/52 (88.46%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFL 317 QRQAAN+RERKRM S+N+AF++LR +PT YEKRLS+++TLR+AI YI+F+ Sbjct: 16 QRQAANIRERKRMFSLNEAFDELRKKVPTFAYEKRLSRIETLRLAIVYISFM 67
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Cavefish
Match: scxa (scleraxis bHLH transcription factor a [Source:ZFIN;Acc:ZDB-GENE-060503-414]) HSP 1 Score: 73.1738 bits (178), Expect = 7.621e-16 Identity = 33/63 (52.38%), Postives = 44/63 (69.84%), Query Frame = 3 Query: 156 ARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQG 344 RQR AAN RER R S+N AF LR IPT P +++LSK++TLR+A YI+ LG ++ V +G Sbjct: 77 GRQRNAANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLVGEG 139
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Cavefish
Match: twist1a (twist family bHLH transcription factor 1a [Source:ZFIN;Acc:ZDB-GENE-000210-6]) HSP 1 Score: 70.4774 bits (171), Expect = 3.178e-15 Identity = 39/92 (42.39%), Postives = 61/92 (66.30%), Query Frame = 3 Query: 123 RFSRSKCP---EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQ-GEEIYEKTFIANDQF 386 R RS P E+L QR AN+RER+R QS+N+AF LR IPT+P +K LSK+ TL++A YI+FL ++Q D+ ++ +++A+++ Sbjct: 51 RGKRSSSPQSFEELQTQRVMANVRERQRTQSLNEAFASLRKIIPTLPSDK-LSKIQTLKLAARYIDFLCQVLQSDELDSKVASCSYVAHERL 141
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004072.1 (pep scaffold:Pmarinus_7.0:GL492732:1750:4325:-1 gene:ENSPMAG00000003727.1 transcript:ENSPMAT00000004072.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 97.8265 bits (242), Expect = 2.463e-25 Identity = 44/60 (73.33%), Postives = 52/60 (86.67%), Query Frame = 3 Query: 153 LARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQ 332 ++ RQAAN RER+RMQSIN AFE LR HIPT+PYEKRLSKVDTLR+AIGYI+FLG ++ Sbjct: 129 MSHLRQAANQRERRRMQSINAAFEGLRAHIPTLPYEKRLSKVDTLRLAIGYISFLGELVH 188
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Sea Lamprey
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410]) HSP 1 Score: 91.2781 bits (225), Expect = 3.779e-24 Identity = 41/65 (63.08%), Postives = 49/65 (75.38%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIY 356 QR AAN+RER+RM SIN AFE+LR H+PT PYEKRLSK+DTLR+AI YI L I+ D + Y Sbjct: 34 QRTAANVRERRRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLRDILLSDTDPKAY 98
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Sea Lamprey
Match: TWIST1 (twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428]) HSP 1 Score: 67.3958 bits (163), Expect = 3.253e-15 Identity = 35/81 (43.21%), Postives = 57/81 (70.37%), Query Frame = 3 Query: 147 EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGE-EIYEKTFIANDQF 386 E L QR AN+RER+R QS+N+AF LR IPT+P +K LSK+ TL++A YI+FL ++Q D+ + ++ +++A+++ Sbjct: 4 EDLQNQRVLANVRERQRTQSLNEAFASLRKIIPTLPSDK-LSKIQTLKLASRYIDFLYQVLQSDEMDNKMTSCSYVAHERL 83
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Sea Lamprey
Match: scxa (scleraxis bHLH transcription factor a [Source:ZFIN;Acc:ZDB-GENE-060503-414]) HSP 1 Score: 65.4698 bits (158), Expect = 4.020e-14 Identity = 30/56 (53.57%), Postives = 39/56 (69.64%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIM 329 QR+AAN RER R QS+N AF LR IPT P +++LSK++TL +A YI LG + Sbjct: 37 QRRAANARERDRTQSVNSAFTALRTLIPTEPADRKLSKLETLLLASSYIAHLGNTL 92
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Sea Lamprey
Match: TWIST1 (twist family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12428]) HSP 1 Score: 63.1586 bits (152), Expect = 6.124e-13 Identity = 31/57 (54.39%), Postives = 44/57 (77.19%), Query Frame = 3 Query: 147 EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFL 317 E++ +QR AN+RER+R QS+N+AF LR IPT+P +K LSK+ TL++A YI+FL Sbjct: 91 EEVQQQRFVANVRERQRTQSLNEAFASLRQIIPTLPSDK-LSKIQTLKLATRYIDFL 146
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Nematostella
Match: EDO43849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXI0]) HSP 1 Score: 96.2857 bits (238), Expect = 1.097e-26 Identity = 44/52 (84.62%), Postives = 48/52 (92.31%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFL 317 QR AAN+RERKRMQSIN+AFE LR HIPT+PYEKRLSKVDTLR+AIGYI FL Sbjct: 3 QRHAANLRERKRMQSINEAFEGLRKHIPTLPYEKRLSKVDTLRLAIGYIGFL 54
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Nematostella
Match: EDO42924 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZZ0]) HSP 1 Score: 67.781 bits (164), Expect = 1.224e-15 Identity = 31/57 (54.39%), Postives = 41/57 (71.93%), Query Frame = 3 Query: 159 RQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIM 329 +QRQAAN RER R S+N AF LR+ IPT P +++LSK++TLR+A YI L I+ Sbjct: 1 KQRQAANARERNRTHSVNAAFNALRLLIPTEPSDRKLSKIETLRLASSYIAHLSTIL 57
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Nematostella
Match: EDO46240 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQW6]) HSP 1 Score: 70.4774 bits (171), Expect = 1.943e-15 Identity = 40/83 (48.19%), Postives = 54/83 (65.06%), Query Frame = 3 Query: 153 LARQRQAANMRERKRMQSINDAFEKLRVHIP--TMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTE 395 L++QRQ AN RER RM+SI+DA LR H+P + +K+LSK+ TLR+AI YI+ L I+Q D G+ I I+N Q E Sbjct: 35 LSKQRQTANARERNRMRSISDALLHLRYHLPQTVVAKDKKLSKIQTLRLAIRYISDLFEILQSDDGQGIN----ISNGQLCAE 113
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Nematostella
Match: TWIST (Predicted protein; Twist family bHLH transcription factor [Source:UniProtKB/TrEMBL;Acc:Q6S5G7]) HSP 1 Score: 63.1586 bits (152), Expect = 3.425e-13 Identity = 34/77 (44.16%), Postives = 52/77 (67.53%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQG--EEIYEKTFIANDQF 386 QR AN+RER+R Q++N+AF KLR IPT+P +K LSK+ TLR+A YI+FL ++ ++ +FIA+++ Sbjct: 37 QRAIANVRERQRTQALNEAFNKLRKIIPTLPSDK-LSKIQTLRLASRYIDFLCQVLGNNEKHPSSALSSSFIAHERL 112
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Nematostella
Match: EDO46194 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQN4]) HSP 1 Score: 64.3142 bits (155), Expect = 1.694e-12 Identity = 36/98 (36.73%), Postives = 55/98 (56.12%), Query Frame = 3 Query: 165 RQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQ-VDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFANSESNYI 455 R N +ER R QS+N AF ++R +PT P +K+LSKV+ LR A+ YI FL G+++ + GEEI + + L+ S + SE N++ Sbjct: 52 RTVTNKKERWRQQSVNLAFAEIRKLLPTYPPDKKLSKVEILRTAVKYIQFLDGVLEGMGDGEEIRGRDVPGELPWMPNRTLRGSF----WGLSEYNHV 145
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Medaka
Match: ptf1a (pancreas associated transcription factor 1a [Source:NCBI gene;Acc:101160350]) HSP 1 Score: 103.99 bits (258), Expect = 6.728e-27 Identity = 47/63 (74.60%), Postives = 56/63 (88.89%), Query Frame = 3 Query: 150 KLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 ++ + RQAAN+RER+RMQSINDAFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL ++Q D Sbjct: 115 EMQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLAELVQSD 177
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Medaka
Match: si:dkey-34f9.3 (si:dkey-34f9.3 [Source:ZFIN;Acc:ZDB-GENE-081104-410]) HSP 1 Score: 87.4261 bits (215), Expect = 3.101e-21 Identity = 43/71 (60.56%), Postives = 53/71 (74.65%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEE-IYEKTFI 371 QR AAN+RERKRM SIN AFE+LR H+PT PYEKRLSK+DTLR+AI YI L I+ E+ +++K I Sbjct: 125 QRHAANIRERKRMLSINSAFEELRCHVPTFPYEKRLSKIDTLRLAIAYIALLREILLSGATEKMLFKKELI 195
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Medaka
Match: ferd3l (Fer3 like bHLH transcription factor [Source:NCBI gene;Acc:101167882]) HSP 1 Score: 77.0258 bits (188), Expect = 1.135e-18 Identity = 33/57 (57.89%), Postives = 49/57 (85.96%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQ 332 QRQAAN+RER+RM S+N+AF++LR +PT YEKRLS+++TLR+AI YI+F+ +++ Sbjct: 15 QRQAANVRERRRMFSLNEAFDELRRKVPTFAYEKRLSRIETLRLAIVYISFMTDLLE 71
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Medaka
Match: scxb (scleraxis bHLH transcription factor [Source:NCBI gene;Acc:101167982]) HSP 1 Score: 72.4034 bits (176), Expect = 1.772e-15 Identity = 33/67 (49.25%), Postives = 45/67 (67.16%), Query Frame = 3 Query: 144 PEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQG 344 P RQR AAN RER R S+N AF LR IPT P +++LSK++TLR+A YI+ LG ++ + +G Sbjct: 91 PHVEVRQRTAANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLLGEG 157
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Medaka
Match: twist2 (twist2 [Source:ZFIN;Acc:ZDB-GENE-980526-235]) HSP 1 Score: 68.9366 bits (167), Expect = 1.553e-14 Identity = 46/121 (38.02%), Postives = 71/121 (58.68%), Query Frame = 3 Query: 60 QKVLNRKSHLKKNFPRKNSDSR---FSRSKCP--------EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGE-EIYEKTFIANDQF 386 QK RK K F +S S R+K P E+L QR AN+RER+R QS+N+AF LR IPT+P +K LSK+ TL++A YI+FL ++Q D+ + ++ +++A+++ Sbjct: 29 QKRFARKRRHSKKFSEDSSGSSPGPVKRAKKPSPSSTQSYEELQNQRVLANVRERQRTQSLNEAFASLRKIIPTLPSDK-LSKIQTLKLASRYIDFLCQVLQSDEMDSKMSSCSYVAHERL 148
BLAST of Pancreas transcription factor 1 subunit alpha vs. Planmine SMEST
Match: SMESG000044960.1 (SMESG000044960.1) HSP 1 Score: 372.474 bits (955), Expect = 1.934e-133 Identity = 176/177 (99.44%), Postives = 177/177 (100.00%), Query Frame = 3 Query: 75 RKSHLKKNFPRKNSDSRFSRSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFANSESNYIDYYGWAHANSIQNFYPEINSTVDVIQKRTNQIFQNCYNYTNEFEYPFLSC 605 +KSHLKKNFPRKNSDSRFSRSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFANSESNYIDYYGWAHANSIQNFYPEINSTVDVIQKRTNQIFQNCYNYTNEFEYPFLSC Sbjct: 18 KKSHLKKNFPRKNSDSRFSRSKCPEKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFANSESNYIDYYGWAHANSIQNFYPEINSTVDVIQKRTNQIFQNCYNYTNEFEYPFLSC 194
BLAST of Pancreas transcription factor 1 subunit alpha vs. Planmine SMEST
Match: SMESG000044960.1 (SMESG000044960.1) HSP 1 Score: 252.677 bits (644), Expect = 3.207e-87 Identity = 119/119 (100.00%), Postives = 119/119 (100.00%), Query Frame = 3 Query: 249 MPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFANSESNYIDYYGWAHANSIQNFYPEINSTVDVIQKRTNQIFQNCYNYTNEFEYPFLSC 605 MPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFANSESNYIDYYGWAHANSIQNFYPEINSTVDVIQKRTNQIFQNCYNYTNEFEYPFLSC Sbjct: 1 MPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEIYEKTFIANDQFQTESNLKSSHLPYSFANSESNYIDYYGWAHANSIQNFYPEINSTVDVIQKRTNQIFQNCYNYTNEFEYPFLSC 119
BLAST of Pancreas transcription factor 1 subunit alpha vs. Planmine SMEST
Match: SMESG000079648.1 (SMESG000079648.1) HSP 1 Score: 104.375 bits (259), Expect = 1.972e-27 Identity = 47/64 (73.44%), Postives = 57/64 (89.06%), Query Frame = 3 Query: 147 EKLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVD 338 +KL QRQAAN+RER+RMQSIN+AFE LR HIPT+PYEKRLSKVDTLR+AIGYINFL +++ + Sbjct: 98 QKLVFQRQAANLRERRRMQSINEAFEGLRAHIPTLPYEKRLSKVDTLRLAIGYINFLQDLVKTE 161
BLAST of Pancreas transcription factor 1 subunit alpha vs. Planmine SMEST
Match: SMESG000000956.1 (SMESG000000956.1) HSP 1 Score: 100.523 bits (249), Expect = 8.874e-26 Identity = 48/65 (73.85%), Postives = 56/65 (86.15%), Query Frame = 3 Query: 150 KLARQRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQG 344 KLA +RQAAN+RER+RMQSIN+AFE LR HIPTMPYEKRLSKVDTLR+AI YI FL +++ D G Sbjct: 100 KLA-ERQAANIRERRRMQSINEAFEGLRCHIPTMPYEKRLSKVDTLRLAISYIGFLQELIKSDCG 163
BLAST of Pancreas transcription factor 1 subunit alpha vs. Planmine SMEST
Match: SMESG000029000.1 (SMESG000029000.1) HSP 1 Score: 75.8702 bits (185), Expect = 9.000e-17 Identity = 33/64 (51.56%), Postives = 48/64 (75.00%), Query Frame = 3 Query: 162 QRQAANMRERKRMQSINDAFEKLRVHIPTMPYEKRLSKVDTLRMAIGYINFLGGIMQVDQGEEI 353 QR+AAN+RER+RM S+N+AF+ LR +PT YEKRLS+++TLR+AI YI F+ ++ + I Sbjct: 138 QRRAANIRERRRMYSLNEAFDSLRKRVPTFAYEKRLSRIETLRLAITYICFMTELLNGKNADNI 201 The following BLAST results are available for this feature:
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Pancreas transcription factor 1 subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034009 ID=SMED30034009|Name=Pancreas transcription factor 1 subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=615bpback to top protein sequence of SMED30034009-orf-1 >SMED30034009-orf-1 ID=SMED30034009-orf-1|Name=SMED30034009-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=202bp YFLKENFKCVKILIVILKFQKVLNRKSHLKKNFPRKNSDSRFSRSKCPEKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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