Copine-3
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033990 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498]) HSP 1 Score: 463.766 bits (1192), Expect = 2.870e-156 Identity = 252/540 (46.67%), Postives = 341/540 (63.15%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKA-LNKAVLFELPGQVVSWMKSNSI 1721
+RVE+SV+C+NL D D FSKSDP+ VL+ + N + E RTE I N LNP F + F +DY FEER+ + ++YD+DS S L H+FLG +LGE+V + S+L V +K I+LT EL+ ++ + +QF KLDKKD FGKSDP L YRS N +F + ++T+ + NTLNP W F + + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK KK+ Y NSGT+TL V+ E SF DYI GGT++NFTVAIDFTASN N P SLH++ N Y A+ +VG I+QDYDSDKMFPALGFGA++PP+ ISH F +N +PQNP+C GI G++ Y ++++V LYGPTNF+P I HV ++A +DGS+YFVLLI+TDG+ISD T ++I++ S LPMSIII+GVG ++ AM LD D + + K A+RDIVQFV RD++D I A L K VL E+P Q +S+M++ I
Sbjct: 24 TRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQG--SRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRS-------------NEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQL----NAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGI 544
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE2 (copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]) HSP 1 Score: 452.981 bits (1164), Expect = 2.428e-152 Identity = 258/544 (47.43%), Postives = 349/544 (64.15%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNE-AFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQY---RDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
+VE+SV+ +NL D D+ SKSDP VLF E N ++E DRTET NNLNP F+K F +DYHFEE Q K ++D D SS RL +H+FLG F SLG +VS +K+ L +++ LI + ELS ++ +I L G +LDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ I+++C D+++ G DFIG TSV+ + E + F IN +K+ KK++Y NSG + L + +YSF DYI GG +L FTV IDFTASN N +P SLH+I P N+Y +AI +VG IIQDYDSDKMFPALGFGA++PP+ ++SH F INF+P NPFC+G+ G+ Y + + + YGPTNFSP + HV +FA Q R ++YF+LLIITDG+ISD E T A++ S LPMSIII+GVGN D++AM+ LD D +LR + + A RDIVQFV R+F R A ++ L KAVL ELP QVV + K ++ P
Sbjct: 25 KVELSVSGQNLLDRDVTSKSDPFCVLFTENNGRWIEYDRTETAINNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSMRLDEHDFLGQFSCSLGTIVSSKKITRPL--LLLNDKPAGKGLITIAAQELSDNR-VITLSLAGRRLDKKDLFGKSDPFLEFYKPGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGHDFIGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMG-----TNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREF---RNAA--KETLAKAVLAELPQQVVQYFKHKNLPP 542
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE2 (copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]) HSP 1 Score: 452.981 bits (1164), Expect = 2.428e-152 Identity = 258/544 (47.43%), Postives = 349/544 (64.15%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNE-AFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQY---RDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
+VE+SV+ +NL D D+ SKSDP VLF E N ++E DRTET NNLNP F+K F +DYHFEE Q K ++D D SS RL +H+FLG F SLG +VS +K+ L +++ LI + ELS ++ +I L G +LDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ I+++C D+++ G DFIG TSV+ + E + F IN +K+ KK++Y NSG + L + +YSF DYI GG +L FTV IDFTASN N +P SLH+I P N+Y +AI +VG IIQDYDSDKMFPALGFGA++PP+ ++SH F INF+P NPFC+G+ G+ Y + + + YGPTNFSP + HV +FA Q R ++YF+LLIITDG+ISD E T A++ S LPMSIII+GVGN D++AM+ LD D +LR + + A RDIVQFV R+F R A ++ L KAVL ELP QVV + K ++ P
Sbjct: 25 KVELSVSGQNLLDRDVTSKSDPFCVLFTENNGRWIEYDRTETAINNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSMRLDEHDFLGQFSCSLGTIVSSKKITRPL--LLLNDKPAGKGLITIAAQELSDNR-VITLSLAGRRLDKKDLFGKSDPFLEFYKPGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGHDFIGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMG-----TNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREF---RNAA--KETLAKAVLAELPQQVVQYFKHKNLPP 542
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE2 (copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]) HSP 1 Score: 452.981 bits (1164), Expect = 2.428e-152 Identity = 258/544 (47.43%), Postives = 349/544 (64.15%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNE-AFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQY---RDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
+VE+SV+ +NL D D+ SKSDP VLF E N ++E DRTET NNLNP F+K F +DYHFEE Q K ++D D SS RL +H+FLG F SLG +VS +K+ L +++ LI + ELS ++ +I L G +LDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ I+++C D+++ G DFIG TSV+ + E + F IN +K+ KK++Y NSG + L + +YSF DYI GG +L FTV IDFTASN N +P SLH+I P N+Y +AI +VG IIQDYDSDKMFPALGFGA++PP+ ++SH F INF+P NPFC+G+ G+ Y + + + YGPTNFSP + HV +FA Q R ++YF+LLIITDG+ISD E T A++ S LPMSIII+GVGN D++AM+ LD D +LR + + A RDIVQFV R+F R A ++ L KAVL ELP QVV + K ++ P
Sbjct: 25 KVELSVSGQNLLDRDVTSKSDPFCVLFTENNGRWIEYDRTETAINNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSMRLDEHDFLGQFSCSLGTIVSSKKITRPL--LLLNDKPAGKGLITIAAQELSDNR-VITLSLAGRRLDKKDLFGKSDPFLEFYKPGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGHDFIGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMG-----TNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREF---RNAA--KETLAKAVLAELPQQVVQYFKHKNLPP 542
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE5 (copine 5 [Source:HGNC Symbol;Acc:HGNC:2318]) HSP 1 Score: 449.129 bits (1154), Expect = 3.620e-150 Identity = 253/571 (44.31%), Postives = 356/571 (62.35%), Query Frame = 3
Query: 87 AEMNSIQDEL-KSRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELV----SRRKVESKLSNRFVDNNTRKPQ--------------LIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
+E +S+ + ++VEI+V+C+NL D D+FSKSDP+ V++ + N + E RTE I N LNP F + F +DY FEE+Q + ++YD+DS S L H+FLG +LGE+V SR + + +++ T KP I+L+ ELS+ +++ +QF KLDKKD FGKSDP L YRS++ +GT F + ++T+ + NTLNP W FS+ + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK+KK+ Y NSGT+TL +V+ E +F DYI GGT++NFTVAIDFTASN N SLH++ N Y A+ +VG IIQ YDSDKMFPALGFGA++PP+ +SH FP+N + +NP C GI G+L Y ++R V LYGPTNF+P + HV + A +DGS+Y VLLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD++D RT ++ L + VL E+P Q+VS+MK+ I
Sbjct: 11 SEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNE-----------DGT--FTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQL----NAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVD-RTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. Ensembl Celegans
Match: nra-1 (Nicotinic receptor-associated protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUB9]) HSP 1 Score: 362.844 bits (930), Expect = 9.785e-117 Identity = 225/574 (39.20%), Postives = 312/574 (54.36%), Query Frame = 3
Query: 117 KSRVEISVACKNLKDMDIFSKSDPMAVLFQEF-----------------NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSS--NRLVDHEFLGDFKFSLGELVSRRKVESKLSN--------RFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYNN--SGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASN--ENNPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQY-RDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMD-----IRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
K+ V ++++ NL D+D+FSKSDP+ +++++ + + E RTE + NNLNP FTK F + Y FEE Q+ + EIYD DS + L H+FLG F+ L ++VS +++ L R D NT+ + + E E I G LDKKD FGKSDP L R D +G+ + + + KP TL+P W + LC + DR I + C D + K D IG T++N LL +L NEKK K+ SGTL + + + E +F D+ISGGT+L+F VA+DFTASN + SLHF+ A NQYE A+ SV SI Q Y+S K F A GFGA++P +S FP++ GITG++ YR A+ V LYGPTNF+P I +V + A D ++Y +LLIITDGIISD ATI +II S LP+SIIIIGVGNED+ M LD D LL+ ++IAQRDIVQFV +R+F++ + Q+ L + VL+E+P Q+ +MK P
Sbjct: 14 KTNVRLTISANNLMDLDVFSKSDPICLIYEKTSGRKATTTEEITVPTWKDKQWTERGRTEVVMNNLNPQFTKTFLLPYFFEETQLLRFEIYDADSPTVGQDLSSHDFLGRFECVLAQIVSYSTLKAHLGKTGQIGAQWRNKDKNTKTGSITIYA--EEDEKAEKIQFDVCGEGLDKKDFFGKSDPYLNFKRKFD-----------DGSTHLIHRTEVKP--KTLDPRWATVQINTQTLCAKDGDRPIIIECYDHDKWKKDDLIGTAQTTLNELLRGSSDAVEILLTNEKKKAKKGDKYKCSGTLKIWNSRIVIEPTFLDFISGGTQLDFAVAVDFTASNGPPKSSSSLHFMS----ADRPNQYELALRSVLSICQHYNSSKTFEAFGFGAKLPNQSSVSAIFPLDLQRGTSEVVGITGVMTAYRHALSNVQLYGPTNFAPIIENVARKAQNMIHDSARYQILLIITDGIISDMHATIRSIISASGLPLSIIIIGVGNEDFEKMHELDSDDALLQQDSRIAQRDIVQFVTMREFLNNGQGLYLDPDVIQENLAREVLYEVPAQLTGYMKQRGFQP 568
BLAST of Copine-3 vs. Ensembl Celegans
Match: gem-4 (Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMBL;Acc:Q22422]) HSP 1 Score: 355.91 bits (912), Expect = 4.869e-114 Identity = 224/577 (38.82%), Postives = 322/577 (55.81%), Query Frame = 3
Query: 117 KSRVEISVACKNLKDMDIFSKSDPMAVLFQEF-----------------NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSS--SNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFV-------DNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLD-FIGHCFTSVNHLLENQRKNEA--FVLINEKKIKKRSYN--NSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQY-RDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMD------IRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
K+ V ++++ NL D+D+FSKSDP+ +++++ + + E RTE I N+LNP F F I Y FEE Q+F+ E+YD+DS + H+FLG F+ L ++VS + + L + + K I + E ++++ F G KLD+KD FGKSDP L R D +G+ + +++QT+ TLNP W + LC DR I + C D K D IG T++N L+E E+ LINEKK K+ NSG L + A + E +F D+I+GGT+L+F VA+DFTASN N P SLH++ G NQYE A+ SV +I Q Y+S K F A GFGA++P ++ +S FP++ + Q+ GI G++N YR A++ V LYGPTNFSP I V A + + ++Y +LLIITDGIISD ATI+ +I+ S LP+SIIIIGVGNED+ M LD D LL+ ++IA+RDIVQFV +RDF+ + T I + L + VL+E+P Q+ +MK P
Sbjct: 15 KTNVRLTISASNLMDLDVFSKSDPICIIYEKTSGRKATTTDPIAVVTWQDRQWTERGRTEIIWNDLNPQFKTTFLIPYFFEETQLFRFELYDVDSPKVGADMSGHDFLGRFECVLAQIVSYSTLRAHLGGKHSIGAQWKNKDKVSKNGSITIRAEEDEKNEKIQF-DVCGEKLDRKDFFGKSDPYLNFKRRFD-----------DGSSH--MIHQTEVKPKTLNPRWSTVLISTQALCGKNMDRPIIIECYDHEKFKKQDDIIGTAQTTLNTLIEQAGGGESTQIPLINEKKKLKKGAKYKNSGMLKIWNAKLVLEPTFLDFIAGGTQLDFAVAVDFTASNGNPRTPGSLHYMA----TGIPNQYEIALRSVLTICQHYNSSKTFEAYGFGAKLPNHQTVSAVFPLDLNRQSSSVVGINGVMNAYRHALQNVTLYGPTNFSPIIVEVANKAQKMMKTTARYQILLIITDGIISDMYATINTVINASGLPLSIIIIGVGNEDFERMHELDSDDALLQQDSRIAERDIVQFVTMRDFLGNQSGGYLNTDTIMEN-LAREVLYEVPDQLTGYMKRRGFTP 572
BLAST of Copine-3 vs. Ensembl Celegans
Match: gem-4 (Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMBL;Acc:Q22422]) HSP 1 Score: 355.91 bits (912), Expect = 4.869e-114 Identity = 224/577 (38.82%), Postives = 322/577 (55.81%), Query Frame = 3
Query: 117 KSRVEISVACKNLKDMDIFSKSDPMAVLFQEF-----------------NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSS--SNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFV-------DNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLD-FIGHCFTSVNHLLENQRKNEA--FVLINEKKIKKRSYN--NSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQY-RDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMD------IRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
K+ V ++++ NL D+D+FSKSDP+ +++++ + + E RTE I N+LNP F F I Y FEE Q+F+ E+YD+DS + H+FLG F+ L ++VS + + L + + K I + E ++++ F G KLD+KD FGKSDP L R D +G+ + +++QT+ TLNP W + LC DR I + C D K D IG T++N L+E E+ LINEKK K+ NSG L + A + E +F D+I+GGT+L+F VA+DFTASN N P SLH++ G NQYE A+ SV +I Q Y+S K F A GFGA++P ++ +S FP++ + Q+ GI G++N YR A++ V LYGPTNFSP I V A + + ++Y +LLIITDGIISD ATI+ +I+ S LP+SIIIIGVGNED+ M LD D LL+ ++IA+RDIVQFV +RDF+ + T I + L + VL+E+P Q+ +MK P
Sbjct: 15 KTNVRLTISASNLMDLDVFSKSDPICIIYEKTSGRKATTTDPIAVVTWQDRQWTERGRTEIIWNDLNPQFKTTFLIPYFFEETQLFRFELYDVDSPKVGADMSGHDFLGRFECVLAQIVSYSTLRAHLGGKHSIGAQWKNKDKVSKNGSITIRAEEDEKNEKIQF-DVCGEKLDRKDFFGKSDPYLNFKRRFD-----------DGSSH--MIHQTEVKPKTLNPRWSTVLISTQALCGKNMDRPIIIECYDHEKFKKQDDIIGTAQTTLNTLIEQAGGGESTQIPLINEKKKLKKGAKYKNSGMLKIWNAKLVLEPTFLDFIAGGTQLDFAVAVDFTASNGNPRTPGSLHYMA----TGIPNQYEIALRSVLTICQHYNSSKTFEAYGFGAKLPNHQTVSAVFPLDLNRQSSSVVGINGVMNAYRHALQNVTLYGPTNFSPIIVEVANKAQKMMKTTARYQILLIITDGIISDMYATINTVINASGLPLSIIIIGVGNEDFERMHELDSDDALLQQDSRIAERDIVQFVTMRDFLGNQSGGYLNTDTIMEN-LAREVLYEVPDQLTGYMKRRGFTP 572
BLAST of Copine-3 vs. Ensembl Celegans
Match: nra-1 (Nicotinic receptor-associated protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUB9]) HSP 1 Score: 354.369 bits (908), Expect = 1.996e-113 Identity = 225/586 (38.40%), Postives = 312/586 (53.24%), Query Frame = 3
Query: 117 KSRVEISVACKNLKDMDIFSKSDPMAVLFQEF-----------------NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSS--NRLVDHEFLGDFKFSLGELVSRRKVESKLSN--------RFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTD---WNSS---------GKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYNN--SGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASN--ENNPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQY-RDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMD-----IRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
K+ V ++++ NL D+D+FSKSDP+ +++++ + + E RTE + NNLNP FTK F + Y FEE Q+ + EIYD DS + L H+FLG F+ L ++VS +++ L R D NT+ + + E E I G LDKKD FGKSDP L R D +G+ + + + KP TL+P W + LC + DR I + C D W + D IG T++N LL +L NEKK K+ SGTL + + + E +F D+ISGGT+L+F VA+DFTASN + SLHF+ A NQYE A+ SV SI Q Y+S K F A GFGA++P +S FP++ GITG++ YR A+ V LYGPTNF+P I +V + A D ++Y +LLIITDGIISD ATI +II S LP+SIIIIGVGNED+ M LD D LL+ ++IAQRDIVQFV +R+F++ + Q+ L + VL+E+P Q+ +MK P
Sbjct: 14 KTNVRLTISANNLMDLDVFSKSDPICLIYEKTSGRKATTTEEITVPTWKDKQWTERGRTEVVMNNLNPQFTKTFLLPYFFEETQLLRFEIYDADSPTVGQDLSSHDFLGRFECVLAQIVSYSTLKAHLGKTGQIGAQWRNKDKNTKTGSITIYA--EEDEKAEKIQFDVCGEGLDKKDFFGKSDPYLNFKRKFD-----------DGSTHLIHRTEVKP--KTLDPRWATVQINTQTLCAKDGDRPIIIECYDHDKWKKGEEPRGDAKFSRDDLIGTAQTTLNELLRGSSDAVEILLTNEKKKAKKGDKYKCSGTLKIWNSRIVIEPTFLDFISGGTQLDFAVAVDFTASNGPPKSSSSLHFMS----ADRPNQYELALRSVLSICQHYNSSKTFEAFGFGAKLPNQSSVSAIFPLDLQRGTSEVVGITGVMTAYRHALSNVQLYGPTNFAPIIENVARKAQNMIHDSARYQILLIITDGIISDMHATIRSIISASGLPLSIIIIGVGNEDFEKMHELDSDDALLQQDSRIAQRDIVQFVTMREFLNNGQGLYLDPDVIQENLAREVLYEVPAQLTGYMKQRGFQP 580
BLAST of Copine-3 vs. Ensembl Celegans
Match: cpna-5 (Copine family protein 5 [Source:UniProtKB/Swiss-Prot;Acc:Q09219]) HSP 1 Score: 191.045 bits (484), Expect = 4.302e-52 Identity = 148/512 (28.91%), Postives = 255/512 (49.80%), Query Frame = 3
Query: 264 NPVFTKNFEIDYHFEERQMFKI---EIYDID--SSSNR--------LVDHEFLGDFKFSL-------GELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKD-LFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINE-KKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNENNPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSK---YFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMD-IRTQAINQKALNKAVLFELPGQVVSWMKSNSI 1721
N VFT F Y FE+ Q+ K +D D SSS+R VD E +G F L G + S ++++ ++ ++ E+ ++ I +QF G LD+KD L+ ++ +++R E K + + FL Y+++ + N +P W EF + ++ ++RL+++ + GK +IG T+ + + + +IN+ KK +K+SY NSG + L K + YSF DYI GT+L+F + +DF++ P +H + Q F G + AI ++GSII+DY +++F A G GA+IPP S+ F +NFS +P C G+ G++ YR V + SP I +V + + +R G + Y VL + T G ++D + A+ S P+SI+IIG+G+ D+S++ L C K K +RD+VQF+ L+ ++ +N+ + + L +P +V +M + +I
Sbjct: 52 NIVFTDKFSYQYVFEKTQLIKAVFSRCHDRDKPSSSSRDILATSIFKVD-ELIGSFGLQLRRQLEKNGNIASALSGTQRVTDEYLGG--------IIVSAEMPEKEQPIVVQFHGKSLDRKDFLWDETAVFFRVFRLE--------EGKDDDSLVFL--YESEALKNHSHPQWAEFRLD-TQDAADNRNRLLEIWVMYKDVDGKEGYIGKFLTTYAKMKYGPGSDNVYSVINDVKKAQKKSYENSGKMELVKFTDVSFYSFLDYIVSGTQLHFEIGVDFSS-----PEPVHELDQRRFDG---ELHMAIRAIGSIIRDYTPNRLFAAFGIGAKIPPTFHESNEFFLNFS-MDPICRGLDGVMEAYRKTQTMVTPLKESKLSPVINYVTR--MSHRSGFRGLHYHVLALFTRGEVTDLKEIQQALNSASDAPLSILIIGMGDFDFSSLQKL-CSK------RKDGRRDVVQFIHLKSLLNGAEAPWLNKSRIAETALRHVPQHMVQYMHNANI 525
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5a (copine Va [Source:ZFIN;Acc:ZDB-GENE-081105-9]) HSP 1 Score: 460.685 bits (1184), Expect = 2.422e-155 Identity = 248/543 (45.67%), Postives = 344/543 (63.35%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNS--YLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
++VEI+V+C+NL D D FSKSDP+ +L+ + S + E RTE I N LNP F + + +DY FEE+Q + +IYDIDS S L H+FLG +LGE+V S+L + I+LT EL + ++ +QF KLDKKD FG+SDP + YRS++ +GT F + ++T+ + NTLNP W F++ + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK+KKR Y NSGT+TL V+ E++F DYI G +++FTVAIDFTASN N SLH++ N + N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH FP+N + NP+C G+ G+L Y +++ V LYGPTNF+P I HV ++A +DGS+YFVLLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD+MD RT ++ L K VL E+P Q++ +MKS I P
Sbjct: 23 TKVEITVSCRNLLDRDTFSKSDPLCILYTQGAESKQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDIYDIDSKSPDLAKHDFLGQTFCTLGEIVGSPG--SRLEKPLGGIPGKNCGTIILTAEELGNCRDCATMQFCANKLDKKDFFGRSDPFMVFYRSNE-----------DGT--FTICHKTEVVKNTLNPIWQPFTIPVRALCNGDYDRSIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKLKKRRYINSGTVTLLSFLVEAEHTFLDYIKAGLQIHFTVAIDFTASNGNPSQSTSLHYM--NPYQ--MNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVDNPYCNGMEGILEAYHESLKTVQLYGPTNFAPVINHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYMD-RTGNHVLSMARLAKDVLAEIPDQLILYMKSRGIKP 545
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5b (copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398]) HSP 1 Score: 456.062 bits (1172), Expect = 1.812e-153 Identity = 249/541 (46.03%), Postives = 346/541 (63.96%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
++VEI+V+C+NL D D FSKSDP+ VL+ + + E RTE I N LNP F + + +DY FEE+Q + ++YD+DS S L H+FLG +LGE+V S+L + + IVL+ EL + ++ +QF KLDKKD FGKSDP + YRS++ +GT F + ++T+ + NTLNP W F++ + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK+KK+ Y NSGT+TL SV+ E +F DYI GGT++NFTVAIDFTASN N SLH++ N + N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH FP+N + +NP+C GI G+L Y +++ V LYGPTNF+P + HV ++A +DGS+YF+LLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD+MD RT ++ L K VL E+P Q +S+MKS I
Sbjct: 23 TKVEITVSCRNLLDRDTFSKSDPLCVLYTQGVETKQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQMFCTLGEIVGSPA--SRLEKPLGGISGKNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNE-----------DGT--FTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYM--NPYQ--MNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYMD-RTGNHVLSMARLAKDVLAEIPDQFISYMKSRGI 543
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne8 (copine VIII [Source:ZFIN;Acc:ZDB-GENE-100809-1]) HSP 1 Score: 452.21 bits (1162), Expect = 8.281e-152 Identity = 244/551 (44.28%), Postives = 344/551 (62.43%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQE--FNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKA-LNKAVLFELPGQVVSWMKSNSIIPLKQKNRNIS 1754
++VEI+V+C+NL D D FSKSDP+ VL+ + N + E RTE I N LNP F F +DY FEERQ + ++YD+DS S L H+FLG +LGE+V S++ + + +++ EL + +E + +QF G KLDKKD FGKSDP L YRS++ +GT F + ++T+ + NTL+P W F + + LC G+ DR IK+ DW+ G D+IG TS L + + + ++N +KK KK+ Y NSGT+TL + E +F DYI GGT++NFTVAIDFTASN N P SLH++ N Y A+ +VG IIQDYDSDK+FPALGFGA++PP+ +SH FP+N +P NP+C+GI G+L Y ++++V LYGPT FSP I HV ++A +DGS+YF+LLII+DG+ISD T ++I++ S LPMSIII+GVG ++ M LD D+ + + + A+RDIVQFV RD++D R I A L K VL E+P Q + +++S I P + IS
Sbjct: 27 TKVEITVSCRNLLDRDTFSKSDPICVLYTQTVANREWREFGRTEVIDNTLNPDFVHKFILDYFFEERQNLRFDLYDLDSKSENLSKHDFLGQMYCTLGEVVGSPG--SRMERSLIGIPGKNCGTVIVKAEELGNCRESVLMQFCGNKLDKKDFFGKSDPFLVFYRSNE-----------DGT--FTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRAIKIEVYDWDRDGGHDYIGEFSTSYRELSKGHTQFTVWEVLNPKKKKKKKKYLNSGTVTLLSCFIDVEVTFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMSPYHL----NAYALALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPDNPYCSGIEGVLEAYYQSLKSVRLYGPTYFSPVINHVARYASLVKDGSEYFILLIISDGVISDMAQTKESIVNASSLPMSIIIVGVGPAEFDEMIELDGDEVRISSRGRFAERDIVQFVPFRDYIDRRGNHILSMARLAKDVLAEIPDQFLQYVRSRGIKPQHSAHSTIS 558
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5b (copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398]) HSP 1 Score: 449.514 bits (1155), Expect = 9.023e-151 Identity = 249/547 (45.52%), Postives = 346/547 (63.25%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDH------EFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
++VEI+V+C+NL D D FSKSDP+ VL+ + + E RTE I N LNP F + + +DY FEE+Q + ++YD+DS S L H +FLG +LGE+V S+L + + IVL+ EL + ++ +QF KLDKKD FGKSDP + YRS++ +GT F + ++T+ + NTLNP W F++ + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK+KK+ Y NSGT+TL SV+ E +F DYI GGT++NFTVAIDFTASN N SLH++ N + N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH FP+N + +NP+C GI G+L Y +++ V LYGPTNF+P + HV ++A +DGS+YF+LLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD+MD RT ++ L K VL E+P Q +S+MKS I
Sbjct: 28 TKVEITVSCRNLLDRDTFSKSDPLCVLYTQGVETKQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHKPLELYDFLGQMFCTLGEIVGSPA--SRLEKPLGGISGKNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNE-----------DGT--FTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYM--NPYQ--MNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYMD-RTGNHVLSMARLAKDVLAEIPDQFISYMKSRGI 554
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 446.047 bits (1146), Expect = 8.911e-150 Identity = 253/544 (46.51%), Postives = 343/544 (63.05%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEA-FVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF---ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRN-GNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
++VE+SV NL D D+ SKSDP VLF + + +++E+ RTET NNLNPVF F++DYHFEE Q K ++D D S++L +H+FLG+F +LG +VS +K+ L + I +T ELS ++ +I L G KLDKKD FGKSDP L+ ++ D +++V++T+ I NTL+P W F+V L LC G+ DR IK++C D+++ G DFIG TSV + E + E F IN KK KK+SY NSG + L + +YSF DYI GG +L FTV IDFTASN + P SLH+I P N+Y +AI +VG IIQDYD+DKMFPALGFGA++PP+ ++SH F INF+P NPFC+G+ G++ Y + + + YGPTNFSP I HV +F ALQ ++YF LLIITDG+ISD + T AI+ + LPMSIIIIGVGN D++AM+ LD D LR+ + A RDIVQFV RDF + ++ L K+VL ELP QV + K ++ P
Sbjct: 22 TKVELSVCGANLLDRDVASKSDPFCVLFHDVDGNWVELARTETAINNLNPVFGVKFQVDYHFEEVQKLKFAMFDEDKCSSQLYEHDFLGEFTCTLGVIVSNKKLHRPLI--LANGKPAGKGAITITAQELSDNR-IITLTMCGRKLDKKDFFGKSDPYLEFHKQGD-------------DGKWMMVHRTEVIKNTLDPVWKPFTVPLISLCNGDVDRNIKVLCYDYDNDGGHDFIGEFQTSVTKMSEAENGVEVEFECINPKKQKKKSYKNSGIIILKSCKITRDYSFLDYILGGCQLMFTVGIDFTASNGSPREPSSLHYINPMG-----SNEYLSAIWAVGQIIQDYDTDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVEGIVQAYSNCLPHIRFYGPTNFSPIINHVARFANQALQQDTAAQYFTLLIITDGVISDMDETRHAIVQAAKLPMSIIIIGVGNADFTAMEFLDGDSSALRSYTGEEAVRDIVQFVPFRDFRNAP-----KETLAKSVLAELPQQVTQYFKQRNLSP 539
BLAST of Copine-3 vs. Ensembl Xenopus
Match: CPNE2 (copine II [Source:NCBI gene;Acc:100495261]) HSP 1 Score: 452.21 bits (1162), Expect = 4.693e-152 Identity = 258/545 (47.34%), Postives = 351/545 (64.40%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQR-KNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF--ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLK 1733
RVE+SV+C+NL D D+ SKSDP VLFQE N + EIDRTET NNLNPVF K F I+YHFEE Q K ++D D SS +L +H+FLG+F +LG +VS +K+ L + +I + ELS ++ +I L G KLDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ IK+VC D+++ G DFIG T+ + E++ + F IN +K+ KKRSY NSG + + + +Y+F DYI GG +L FTV IDFTASN N + SLH I P N+Y +A+ SVG IIQDYDSDK+FPALGFGA++PP+ ++SH F INF+P +PFC+G+ G++ Y + + + YGPTNFSP I HV +F ++ ++YF+LLIITDG+ISD + T AI+ S LPMSIIIIGVGN D+SAM+ LD D +LR N + A RDIVQFV R+F + ++ L KAVL ELP QVV + K++++ P+K
Sbjct: 21 RVELSVSCQNLLDRDVASKSDPFCVLFQEVNGKWSEIDRTETTVNNLNPVFAKKFTINYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGMIVSSKKITRPLI--LGNGKPAGKGVITVIAQELSDNR-VITLYMAGRKLDKKDLFGKSDPFLEFYKQGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLQSLCNGDIEKPIKVVCLDYDNDGGHDFIGEFQTTAIKMCESRDFQPVEFECINPKKQKKKRSYKNSGIIIIKSCKITRDYTFLDYILGGCQLMFTVGIDFTASNGNPRDSSSLHHINPMG-----TNEYLSALWSVGQIIQDYDSDKLFPALGFGAQLPPDWKVSHEFAINFNPTSPFCSGVEGIIEAYSACLPNIRFYGPTNFSPIINHVARFAAQATQQEAAQYFILLIITDGVISDMDETRHAIVQASKLPMSIIIIGVGNADFSAMEFLDGDNRVLRSNTGEEASRDIVQFVPFREFRNAP-----KETLAKAVLAELPQQVVDYFKNHNLPPIK 539
BLAST of Copine-3 vs. Ensembl Xenopus
Match: CPNE2 (copine II [Source:NCBI gene;Acc:100495261]) HSP 1 Score: 451.44 bits (1160), Expect = 5.055e-152 Identity = 260/546 (47.62%), Postives = 351/546 (64.29%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQR-KNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF---ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLK 1733
RVE+SV+C+NL D D+ SKSDP VLFQE N + EIDRTET NNLNPVF K F I+YHFEE Q K ++D D SS +L +H+FLG+F +LG +VS +K+ L + +I + ELS ++ +I L G KLDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ IK+VC D+++ G DFIG T+ + E++ + F IN +K+ KKRSY NSG + + + +Y+F DYI GG +L FTV IDFTASN N + SLH I P N+Y +A+ SVG IIQDYDSDK+FPALGFGA++PP+ ++SH F INF+P +PFC+G+ G++ Y + + + YGPTNFSP I HV +F A Q ++YF+LLIITDG+ISD + T AI+ S LPMSIIIIGVGN D+SAM+ LD D +LR N + A RDIVQFV R+F + ++ L KAVL ELP QVV + K++++ P+K
Sbjct: 7 RVELSVSCQNLLDRDVASKSDPFCVLFQEVNGKWSEIDRTETTVNNLNPVFAKKFTINYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGMIVSSKKITRPLI--LGNGKPAGKGVITVIAQELSDNR-VITLYMAGRKLDKKDLFGKSDPFLEFYKQGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLQSLCNGDIEKPIKVVCLDYDNDGGHDFIGEFQTTAIKMCESRDFQPVEFECINPKKQKKKRSYKNSGIIIIKSCKITRDYTFLDYILGGCQLMFTVGIDFTASNGNPRDSSSLHHINPMG-----TNEYLSALWSVGQIIQDYDSDKLFPALGFGAQLPPDWKVSHEFAINFNPTSPFCSGVEGIIEAYSACLPNIRFYGPTNFSPIINHVARFAAQATQQEAAAQYFILLIITDGVISDMDETRHAIVQASKLPMSIIIIGVGNADFSAMEFLDGDNRVLRSNTGEEASRDIVQFVPFREFRNAP-----KETLAKAVLAELPQQVVDYFKNHNLPPIK 526
BLAST of Copine-3 vs. Ensembl Xenopus
Match: CPNE2 (copine II [Source:NCBI gene;Acc:100495261]) HSP 1 Score: 451.825 bits (1161), Expect = 6.352e-152 Identity = 260/546 (47.62%), Postives = 351/546 (64.29%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQR-KNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF---ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLK 1733
RVE+SV+C+NL D D+ SKSDP VLFQE N + EIDRTET NNLNPVF K F I+YHFEE Q K ++D D SS +L +H+FLG+F +LG +VS +K+ L + +I + ELS ++ +I L G KLDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ IK+VC D+++ G DFIG T+ + E++ + F IN +K+ KKRSY NSG + + + +Y+F DYI GG +L FTV IDFTASN N + SLH I P N+Y +A+ SVG IIQDYDSDK+FPALGFGA++PP+ ++SH F INF+P +PFC+G+ G++ Y + + + YGPTNFSP I HV +F A Q ++YF+LLIITDG+ISD + T AI+ S LPMSIIIIGVGN D+SAM+ LD D +LR N + A RDIVQFV R+F + ++ L KAVL ELP QVV + K++++ P+K
Sbjct: 23 RVELSVSCQNLLDRDVASKSDPFCVLFQEVNGKWSEIDRTETTVNNLNPVFAKKFTINYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGMIVSSKKITRPLI--LGNGKPAGKGVITVIAQELSDNR-VITLYMAGRKLDKKDLFGKSDPFLEFYKQGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLQSLCNGDIEKPIKVVCLDYDNDGGHDFIGEFQTTAIKMCESRDFQPVEFECINPKKQKKKRSYKNSGIIIIKSCKITRDYTFLDYILGGCQLMFTVGIDFTASNGNPRDSSSLHHINPMG-----TNEYLSALWSVGQIIQDYDSDKLFPALGFGAQLPPDWKVSHEFAINFNPTSPFCSGVEGIIEAYSACLPNIRFYGPTNFSPIINHVARFAAQATQQEAAAQYFILLIITDGVISDMDETRHAIVQASKLPMSIIIIGVGNADFSAMEFLDGDNRVLRSNTGEEASRDIVQFVPFREFRNAP-----KETLAKAVLAELPQQVVDYFKNHNLPPIK 542
BLAST of Copine-3 vs. Ensembl Xenopus
Match: CPNE2 (copine II [Source:NCBI gene;Acc:100495261]) HSP 1 Score: 451.055 bits (1159), Expect = 6.484e-152 Identity = 260/546 (47.62%), Postives = 351/546 (64.29%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQR-KNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF---ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLK 1733
RVE+SV+C+NL D D+ SKSDP VLFQE N + EIDRTET NNLNPVF K F I+YHFEE Q K ++D D SS +L +H+FLG+F +LG +VS +K+ L + +I + ELS ++ +I L G KLDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ IK+VC D+++ G DFIG T+ + E++ + F IN +K+ KKRSY NSG + + + +Y+F DYI GG +L FTV IDFTASN N + SLH I P N+Y +A+ SVG IIQDYDSDK+FPALGFGA++PP+ ++SH F INF+P +PFC+G+ G++ Y + + + YGPTNFSP I HV +F A Q ++YF+LLIITDG+ISD + T AI+ S LPMSIIIIGVGN D+SAM+ LD D +LR N + A RDIVQFV R+F + ++ L KAVL ELP QVV + K++++ P+K
Sbjct: 8 RVELSVSCQNLLDRDVASKSDPFCVLFQEVNGKWSEIDRTETTVNNLNPVFAKKFTINYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGMIVSSKKITRPLI--LGNGKPAGKGVITVIAQELSDNR-VITLYMAGRKLDKKDLFGKSDPFLEFYKQGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLQSLCNGDIEKPIKVVCLDYDNDGGHDFIGEFQTTAIKMCESRDFQPVEFECINPKKQKKKRSYKNSGIIIIKSCKITRDYTFLDYILGGCQLMFTVGIDFTASNGNPRDSSSLHHINPMG-----TNEYLSALWSVGQIIQDYDSDKLFPALGFGAQLPPDWKVSHEFAINFNPTSPFCSGVEGIIEAYSACLPNIRFYGPTNFSPIINHVARFAAQATQQEAAAQYFILLIITDGVISDMDETRHAIVQASKLPMSIIIIGVGNADFSAMEFLDGDNRVLRSNTGEEASRDIVQFVPFREFRNAP-----KETLAKAVLAELPQQVVDYFKNHNLPPIK 527
BLAST of Copine-3 vs. Ensembl Xenopus
Match: CPNE2 (copine II [Source:NCBI gene;Acc:100495261]) HSP 1 Score: 451.055 bits (1159), Expect = 1.680e-151 Identity = 260/546 (47.62%), Postives = 351/546 (64.29%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQR-KNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF---ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLK 1733
RVE+SV+C+NL D D+ SKSDP VLFQE N + EIDRTET NNLNPVF K F I+YHFEE Q K ++D D SS +L +H+FLG+F +LG +VS +K+ L + +I + ELS ++ +I L G KLDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ IK+VC D+++ G DFIG T+ + E++ + F IN +K+ KKRSY NSG + + + +Y+F DYI GG +L FTV IDFTASN N + SLH I P N+Y +A+ SVG IIQDYDSDK+FPALGFGA++PP+ ++SH F INF+P +PFC+G+ G++ Y + + + YGPTNFSP I HV +F A Q ++YF+LLIITDG+ISD + T AI+ S LPMSIIIIGVGN D+SAM+ LD D +LR N + A RDIVQFV R+F + ++ L KAVL ELP QVV + K++++ P+K
Sbjct: 31 RVELSVSCQNLLDRDVASKSDPFCVLFQEVNGKWSEIDRTETTVNNLNPVFAKKFTINYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGMIVSSKKITRPLI--LGNGKPAGKGVITVIAQELSDNR-VITLYMAGRKLDKKDLFGKSDPFLEFYKQGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLQSLCNGDIEKPIKVVCLDYDNDGGHDFIGEFQTTAIKMCESRDFQPVEFECINPKKQKKKRSYKNSGIIIIKSCKITRDYTFLDYILGGCQLMFTVGIDFTASNGNPRDSSSLHHINPMG-----TNEYLSALWSVGQIIQDYDSDKLFPALGFGAQLPPDWKVSHEFAINFNPTSPFCSGVEGIIEAYSACLPNIRFYGPTNFSPIINHVARFAAQATQQEAAAQYFILLIITDGVISDMDETRHAIVQASKLPMSIIIIGVGNADFSAMEFLDGDNRVLRSNTGEEASRDIVQFVPFREFRNAP-----KETLAKAVLAELPQQVVDYFKNHNLPPIK 550
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne8 (copine VIII [Source:MGI Symbol;Acc:MGI:1914121]) HSP 1 Score: 466.848 bits (1200), Expect = 1.860e-157 Identity = 253/540 (46.85%), Postives = 341/540 (63.15%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKA-LNKAVLFELPGQVVSWMKSNSI 1721
+RVE+SV+C+NL D D FSKSDP+ VL+ + N + E RTE I N LNP F + F +DY FEER+ + ++YD+DS S L H+FLG +LGE+V + S+L V RK I+LT EL+ ++ + +QF KLDKKD FGKSDP L YRS N +F + ++T+ + NTLNP W F + + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK KK+ Y NSGT+TL V+ E SF DYI GGT++NFTVAIDFTASN N P SLH++ N Y A+ +VG I+QDYDSDKMFPALGFGA++PP+ ISH F +N +PQNP+C GI G++ Y ++++V LYGPTNF+P I HV ++A +DGS+YFVLLI+TDG+ISD T ++I++ S LPMSIII+GVG ++ AM LD D + + K A+RDIVQFV RD++D I A L K VL E+P Q +S+M++ I
Sbjct: 37 TRVEVSVSCRNLLDRDTFSKSDPICVLYTQAVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQG--SRLEKPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRS-------------NEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQL----NAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGI 557
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne5 (copine V [Source:MGI Symbol;Acc:MGI:2385908]) HSP 1 Score: 452.21 bits (1162), Expect = 1.303e-151 Identity = 257/571 (45.01%), Postives = 358/571 (62.70%), Query Frame = 3
Query: 87 AEMNSIQDEL-KSRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELV--SRRKVESKLSNRFVDNNTR--KPQ--------------LIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
+E +S+ + ++VEI+V+C+NL D D+FSKSDP+ V++ + N + E RTE I N LNP F + F +DY FEE+Q + ++YD+DS S L H+FLG +LGE+V S ++E L+ N+R KP I+L+ ELS+ +++ +QF KLDKKD FGKSDP L YRS++ +GT F + ++T+ + NTLNP W FS+ + LC G+ DR IK+ DW+ G DFIG TS L Q + + +IN +KK+KK+ Y NSGT+TL +V+ E +F DYI GGT++NFTVAIDFTASN N SLH++ N Y A+ +VG IIQ YDSDKMFPALGFGA++PP+ +SH FP+N + +NP C GI G+L Y S++R V LYGPTNF+P + HV + A +DGS+Y VLLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD++D RT ++ L + VL E+P Q+VS+MK+ I
Sbjct: 11 SEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNE-----------DGT--FTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQL----NAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVD-RTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne9 (copine family member IX [Source:MGI Symbol;Acc:MGI:2443052]) HSP 1 Score: 443.351 bits (1139), Expect = 1.080e-148 Identity = 241/540 (44.63%), Postives = 339/540 (62.78%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNS--YLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRS-YNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIR-TQAINQKALNKAVLFELPGQVVSWMKSNSI 1721
+++EI+V+C+NL D+D FSKSDPM VL + S + E RTE I N LNP F + F +DY FEE+Q + ++Y++DS +N +FLG +LGE++ + S++ +K I+LT ELS+ +++ +Q KLDKKD FGKSDP L YRS++ +GT F + ++T+ + NTLNP W FS+ + LC G+ DR +K+ DW+ G DFIG TS L + Q + + ++N +K K+ Y NSGT+TL SV E++F DYI GGT+LNFTVAIDFTASN N P SLH++ + Y A+ +VG IIQDYDSDK+FPA GFGA++PP ISH FP+N + ++P CAGI G+L +Y ++R V LYGPT F+P I V + A + DGS+Y+VLLIITDG+ISD T +AI+ S LPMSIII+GVG + AM+ LD D + + + A+RDIVQFV RD++D Q ++ L K VL E+P Q++S+M++ I
Sbjct: 14 TKIEITVSCRNLLDLDTFSKSDPMVVLHTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQG--SRVERPLTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNE-----------DGT--FTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSA----YAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDI 534
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne2 (copine II [Source:MGI Symbol;Acc:MGI:2387578]) HSP 1 Score: 436.802 bits (1122), Expect = 2.979e-146 Identity = 254/543 (46.78%), Postives = 343/543 (63.17%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKN--EAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF--ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
+VE+SV+ +NL D D+ SKSDP VLF E N ++E DRTET NNLNP F+K F +DYHFEE Q K ++D D SS +L +H+FLG F SLG +VS +K+ L +++ +I + ELS ++ +I L G KLDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ I+++C D++S+G DFIG TSV + E + E + +K+ KK+SY NSG + L + YSF DYI GG +L FTV IDFTASN N +P SLH+I P N+Y +AI +VG IIQDYDSDKMFPALGFGA++PP+ ++SH F INF+P NPFC+G+ G+ Y + + + YGPTNFSP + HV +F + + YF+LLIITDG+ISD E T A++ S LPMSIII+GVGN D++AM+ LD D LR + + A RDIVQFV R+F R A ++ L KAVL ELP QVV + K ++ P
Sbjct: 25 KVELSVSGQNLLDRDVTSKSDPFCVLFIEDNGRWMEFDRTETAVNNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSAQLDEHDFLGQFSCSLGTIVSSKKITRPL--LLMNDKPAGKGVITIAAQELSDNR-VITLSLAGRKLDKKDLFGKSDPFLEFYKPGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDLEKPIQVMCYDYDSNGGHDFIGEFQTSVLQMSEARDGVPLEIECINPKKQRKKKSYKNSGIIILRSCKIHRNYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMG-----TNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQQTATYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDNRRLRSHTGEEAARDIVQFVPFREF---RNAA--KETLAKAVLAELPQQVVQYFKHKNLPP 541
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne2 (copine II [Source:MGI Symbol;Acc:MGI:2387578]) HSP 1 Score: 436.417 bits (1121), Expect = 4.347e-146 Identity = 256/544 (47.06%), Postives = 346/544 (63.60%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKN--EAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF---ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
+VE+SV+ +NL D D+ SKSDP VLF E N ++E DRTET NNLNP F+K F +DYHFEE Q K ++D D SS +L +H+FLG F SLG +VS +K+ L +++ +I + ELS ++ +I L G KLDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ I+++C D++S+G DFIG TSV + E + E + +K+ KK+SY NSG + L + YSF DYI GG +L FTV IDFTASN N +P SLH+I P N+Y +AI +VG IIQDYDSDKMFPALGFGA++PP+ ++SH F INF+P NPFC+G+ G+ Y + + + YGPTNFSP + HV +F A Q + ++YF+LLIITDG+ISD E T A++ S LPMSIII+GVGN D++AM+ LD D LR + + A RDIVQFV R+F R A ++ L KAVL ELP QVV + K ++ P
Sbjct: 25 KVELSVSGQNLLDRDVTSKSDPFCVLFIEDNGRWMEFDRTETAVNNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSAQLDEHDFLGQFSCSLGTIVSSKKITRPL--LLMNDKPAGKGVITIAAQELSDNR-VITLSLAGRKLDKKDLFGKSDPFLEFYKPGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDLEKPIQVMCYDYDSNGGHDFIGEFQTSVLQMSEARDGVPLEIECINPKKQRKKKSYKNSGIIILRSCKIHRNYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMG-----TNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQQTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDNRRLRSHTGEEAARDIVQFVPFREF---RNAA--KETLAKAVLAELPQQVVQYFKHKNLPP 542
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q9DC53|CPNE8_MOUSE (Copine-8 OS=Mus musculus OX=10090 GN=Cpne8 PE=2 SV=3) HSP 1 Score: 466.848 bits (1200), Expect = 1.301e-156 Identity = 253/540 (46.85%), Postives = 341/540 (63.15%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKA-LNKAVLFELPGQVVSWMKSNSI 1721
+RVE+SV+C+NL D D FSKSDP+ VL+ + N + E RTE I N LNP F + F +DY FEER+ + ++YD+DS S L H+FLG +LGE+V + S+L V RK I+LT EL+ ++ + +QF KLDKKD FGKSDP L YRS N +F + ++T+ + NTLNP W F + + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK KK+ Y NSGT+TL V+ E SF DYI GGT++NFTVAIDFTASN N P SLH++ N Y A+ +VG I+QDYDSDKMFPALGFGA++PP+ ISH F +N +PQNP+C GI G++ Y ++++V LYGPTNF+P I HV ++A +DGS+YFVLLI+TDG+ISD T ++I++ S LPMSIII+GVG ++ AM LD D + + K A+RDIVQFV RD++D I A L K VL E+P Q +S+M++ I
Sbjct: 37 TRVEVSVSCRNLLDRDTFSKSDPICVLYTQAVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQG--SRLEKPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRS-------------NEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQL----NAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGI 557
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q86YQ8|CPNE8_HUMAN (Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2) HSP 1 Score: 463.766 bits (1192), Expect = 1.378e-155 Identity = 252/540 (46.67%), Postives = 341/540 (63.15%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKA-LNKAVLFELPGQVVSWMKSNSI 1721
+RVE+SV+C+NL D D FSKSDP+ VL+ + N + E RTE I N LNP F + F +DY FEER+ + ++YD+DS S L H+FLG +LGE+V + S+L V +K I+LT EL+ ++ + +QF KLDKKD FGKSDP L YRS N +F + ++T+ + NTLNP W F + + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK KK+ Y NSGT+TL V+ E SF DYI GGT++NFTVAIDFTASN N P SLH++ N Y A+ +VG I+QDYDSDKMFPALGFGA++PP+ ISH F +N +PQNP+C GI G++ Y ++++V LYGPTNF+P I HV ++A +DGS+YFVLLI+TDG+ISD T ++I++ S LPMSIII+GVG ++ AM LD D + + K A+RDIVQFV RD++D I A L K VL E+P Q +S+M++ I
Sbjct: 24 TRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQG--SRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRS-------------NEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQL----NAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGI 544
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q96FN4|CPNE2_HUMAN (Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3) HSP 1 Score: 452.981 bits (1164), Expect = 1.166e-151 Identity = 258/544 (47.43%), Postives = 349/544 (64.15%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNE-AFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFI-PQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQY---RDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLR-NGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
+VE+SV+ +NL D D+ SKSDP VLF E N ++E DRTET NNLNP F+K F +DYHFEE Q K ++D D SS RL +H+FLG F SLG +VS +K+ L +++ LI + ELS ++ +I L G +LDKKDLFGKSDP L+ Y+ D ++LV++T+ I TL+P W F+V L LC G+ ++ I+++C D+++ G DFIG TSV+ + E + F IN +K+ KK++Y NSG + L + +YSF DYI GG +L FTV IDFTASN N +P SLH+I P N+Y +AI +VG IIQDYDSDKMFPALGFGA++PP+ ++SH F INF+P NPFC+G+ G+ Y + + + YGPTNFSP + HV +FA Q R ++YF+LLIITDG+ISD E T A++ S LPMSIII+GVGN D++AM+ LD D +LR + + A RDIVQFV R+F R A ++ L KAVL ELP QVV + K ++ P
Sbjct: 25 KVELSVSGQNLLDRDVTSKSDPFCVLFTENNGRWIEYDRTETAINNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSMRLDEHDFLGQFSCSLGTIVSSKKITRPL--LLLNDKPAGKGLITIAAQELSDNR-VITLSLAGRRLDKKDLFGKSDPFLEFYKPGD-------------DGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGHDFIGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMG-----TNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREF---RNAA--KETLAKAVLAELPQQVVQYFKHKNLPP 542
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q8JZW4|CPNE5_MOUSE (Copine-5 OS=Mus musculus OX=10090 GN=Cpne5 PE=1 SV=1) HSP 1 Score: 452.21 bits (1162), Expect = 9.117e-151 Identity = 257/571 (45.01%), Postives = 358/571 (62.70%), Query Frame = 3
Query: 87 AEMNSIQDEL-KSRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELV--SRRKVESKLSNRFVDNNTR--KPQ--------------LIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
+E +S+ + ++VEI+V+C+NL D D+FSKSDP+ V++ + N + E RTE I N LNP F + F +DY FEE+Q + ++YD+DS S L H+FLG +LGE+V S ++E L+ N+R KP I+L+ ELS+ +++ +QF KLDKKD FGKSDP L YRS++ +GT F + ++T+ + NTLNP W FS+ + LC G+ DR IK+ DW+ G DFIG TS L Q + + +IN +KK+KK+ Y NSGT+TL +V+ E +F DYI GGT++NFTVAIDFTASN N SLH++ N Y A+ +VG IIQ YDSDKMFPALGFGA++PP+ +SH FP+N + +NP C GI G+L Y S++R V LYGPTNF+P + HV + A +DGS+Y VLLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD++D RT ++ L + VL E+P Q+VS+MK+ I
Sbjct: 11 SEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNE-----------DGT--FTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQL----NAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVD-RTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q9HCH3|CPNE5_HUMAN (Copine-5 OS=Homo sapiens OX=9606 GN=CPNE5 PE=1 SV=2) HSP 1 Score: 449.129 bits (1154), Expect = 1.739e-149 Identity = 253/571 (44.31%), Postives = 356/571 (62.35%), Query Frame = 3
Query: 87 AEMNSIQDEL-KSRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELV----SRRKVESKLSNRFVDNNTRKPQ--------------LIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
+E +S+ + ++VEI+V+C+NL D D+FSKSDP+ V++ + N + E RTE I N LNP F + F +DY FEE+Q + ++YD+DS S L H+FLG +LGE+V SR + + +++ T KP I+L+ ELS+ +++ +QF KLDKKD FGKSDP L YRS++ +GT F + ++T+ + NTLNP W FS+ + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK+KK+ Y NSGT+TL +V+ E +F DYI GGT++NFTVAIDFTASN N SLH++ N Y A+ +VG IIQ YDSDKMFPALGFGA++PP+ +SH FP+N + +NP C GI G+L Y ++R V LYGPTNF+P + HV + A +DGS+Y VLLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD++D RT ++ L + VL E+P Q+VS+MK+ I
Sbjct: 11 SEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNE-----------DGT--FTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQL----NAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVD-RTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. TrEMBL
Match: A0A267EK06 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig019106g2 PE=4 SV=1) HSP 1 Score: 511.916 bits (1317), Expect = 5.336e-171 Identity = 274/561 (48.84%), Postives = 365/561 (65.06%), Query Frame = 3
Query: 114 LKSRVEISVACKNLKDMDIFSKSDPMAVLF--QEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLEN--QRKNEAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPN-KEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLKQKNRNISPQFTGDA 1775
L SRVEISV+C+NL D D+ SKSDP VLF Q +++ EI RTE + N L+P F+ F +D+ FEERQ+ K +IYD+DS S RL +H+FLG+ + S+GELVSRR+ E+ LS K I++TC EL K+++ G KLDKKD GKSDP L+IY+ + IT +E + N R++ LV++T+ I N LNP W +F V L+RLC G + L++ C D++S G DFIG ++S+ L + + ++ LI++KK ++GT+ ++ ++ SF DYI GGTEL+FTVAIDFT SN + +P SLH + + G NQYE AI+SVG I+QDYDSDK FP LGFGA +PP + F + P+NP+CAG+ GLL YRS IRAV LYGPTNFSP I HV A ++ G++YFVLLIITDGII+DFE T AII S LPMSIII+GVG+ED+SAM+ LD D LR G+ IA+RD+VQFV LR F+ + ++ AL K VL ELP QV WM+ I + RN +P G A
Sbjct: 6 LTSRVEISVSCRNLPDRDVTSKSDPQCVLFLRQPGTSNFQEIGRTEKLNNTLDPEFSHRFIVDFMFEERQLVKFQIYDLDSPSARLSEHDFLGELETSIGELVSRRRFETTLSK-----TGHKKSTIIITCFELQECKQIVSFIAEGKKLDKKDFLGKSDPYLEIYQPMEEIT---SENEVNKVRHWTLVHRTEVIKNNLNPRWAKFLVPLNRLCRGNRQLLLRFDCHDYDSDGSHDFIGSFYSSLESLEQEVARSRSAQRTLISKKK------KSAGTIVFSQIGIETIDSFVDYIQGGTELHFTVAIDFTGSNGDPRDPRSLHHVSAD---GRPNQYELAIISVGEIVQDYDSDKQFPGLGFGALLPPMFSGVQDAFSLTLQPENPYCAGMPGLLAAYRSCIRAVRLYGPTNFSPVINHVASMAAAHQTGAQYFVLLIITDGIITDFEKTKQAIIKASSLPMSIIIVGVGDEDFSAMEELDSDDKRLRCGSMIAERDVVQFVPLRRFIQGGSIDRSRYALAKEVLAELPNQVCEWMRRRGIRAGPPRVRNDAPLVAGGA 549
BLAST of Copine-3 vs. TrEMBL
Match: A0A267F787 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011884g2 PE=4 SV=1) HSP 1 Score: 504.982 bits (1299), Expect = 1.739e-168 Identity = 271/555 (48.83%), Postives = 361/555 (65.05%), Query Frame = 3
Query: 114 LKSRVEISVACKNLKDMDIFSKSDPMAVLF--QEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLEN--QRKNEAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPN-KEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLKQKNRNISP 1757
L SRVEISV+C+NL D D+ SKSDP VLF Q +++ EI RTE + N L+P F+ F +D+ FEERQ+ K +IYD+DS S RL +H+FLG+ + S+GELVSRR+ E+ LS K I++TC EL K+++ G KLDKKD GKSDP L+IY+ + IT +E + N R++ LV++T+ I N LNP W +F V L+RLC G + L++ C D++S G DFIG ++S+ L + + ++ LI++KK ++GT+ ++ ++ SF DYI GGTEL+FTVAIDFT SN + +P SLH + + G NQYE AI+SVG I+QDYDSDK FP LGFGA +PP + F + +NP+CAG+ GLL YRS IRAV LYGPTNFSP I HV A ++ G++YFVLLIITDGII+DFE T AII S LPMSIII+GVG+ED+SAM+ LD D LR G+ IA+RD+VQFV LR F+ ++ AL K VL ELP QV WM+ I + RN +P
Sbjct: 6 LTSRVEISVSCRNLPDRDVTSKSDPQCVLFLRQPGTSNFQEIGRTEKLNNTLDPEFSHRFIVDFMFEERQLVKFQIYDLDSPSARLSEHDFLGELETSIGELVSRRRFETTLSK-----TGHKKSTIIITCFELQECKQIVSFIAEGKKLDKKDFLGKSDPYLEIYQPMEEIT---SENEVNKVRHWTLVHRTEVIKNNLNPRWAKFLVPLNRLCRGNRQLLLRFDCHDYDSDGSHDFIGSFYSSLESLEQEVARSRSAQRTLISKKK------KSAGTIVFSQIGIETIDSFVDYIQGGTELHFTVAIDFTGSNGDPRDPRSLHHVSAD---GRPNQYELAIISVGEIVQDYDSDKQFPGLGFGALLPPMFSGVQDAFSLTLQSENPYCAGMPGLLAAYRSCIRAVRLYGPTNFSPVINHVASMAAAHQTGAQYFVLLIITDGIITDFEKTKQAIIKASSLPMSIIIVGVGDEDFSAMEELDSDDKRLRCGSMIAERDVVQFVPLRRFIQGGNIDRSRYALAKEVLAELPNQVCEWMRRRGIRAGPPRVRNDAP 543
BLAST of Copine-3 vs. TrEMBL
Match: A0A267DFW5 (C2 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006534g5 PE=4 SV=1) HSP 1 Score: 493.426 bits (1269), Expect = 4.166e-164 Identity = 266/549 (48.45%), Postives = 346/549 (63.02%), Query Frame = 3
Query: 105 QDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQ--EFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTR-NFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLL---ENQRKNEAFVLINEK-KIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDI-RTQAINQKALNKAVLFELPGQVVSWMKSNSI 1721
Q L SRVEISVAC+ L DMD+ SKSDPM VL +Y E DRTE +K+ LNP F F +D+HFEE Q +YDIDS S +L DH+FLG F+ ++GELVSRR+VE+ L+ + R+ I++TC EL KE++ +Q G++LDKKD GKSDP ++ S P+T + + + R + LVY++ + LNP+W +KLS++C G K +++ C DWN K IG + SV +L EN A + ++ R +G L N+ + E SF DYI GG EL FTV IDFTASN N P SLH+I D +G NQYE AI SVG I+QDYD + FP+ GFGAR+PP +++HCFP+ F+ NP+CAG+ GLL YRS +R+V LYGPTNFSP IRHV Q A + G +YFVLLIITDGII+DF T +II+ S LPMSIII+GVG ED+SAM+ LD D L+ G IA+ DIVQFV LRDF +++ AL KAVL ELP Q+ WM+ I
Sbjct: 9 QQGLVSRVEISVACRKLADMDLTSKSDPMCVLMMCPPGTRNYREQDRTEMLKDTLNPDFQHKFVVDFHFEEHQKVMFCLYDIDSHSTQLSDHDFLGQFESTIGELVSRRRVEAPLAK-----SPRRDSTIIITCIELQHCKEILQMQLCGSQLDKKDFLGKSDPYFEV---SKPLTPVVDSSSSDLLRAQWTLVYRSAVVRKNLNPTWQPTQLKLSQMCNGNKSLILRWDCIDWNKRMKHSHIGTFYASVADILREYENSNSRGATSGAGARFQLLSRRKKPAGYLVFNRLELLIEDSFVDYIQGGCELLFTVGIDFTASNGNPATPQSLHYI---DPSGRLNQYELAITSVGEIVQDYDFRRAFPSFGFGARVPPRGDVNHCFPLTFNDSNPYCAGLAGLLQAYRSCLRSVTLYGPTNFSPIIRHVMQLAQANQSGKQYFVLLIITDGIITDFYETKLSIIEASRLPMSIIIVGVGREDFSAMEELDADNKRLQIGGMIAEADIVQFVPLRDFFRADNPNELSKSALTKAVLEELPDQLCQWMRKRGI 546
BLAST of Copine-3 vs. TrEMBL
Match: A0A1I8IGU8 (C2 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006534g1 PE=4 SV=1) HSP 1 Score: 490.345 bits (1261), Expect = 4.613e-163 Identity = 261/548 (47.63%), Postives = 341/548 (62.23%), Query Frame = 3
Query: 105 QDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQ--EFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLL---ENQRKNEAFVLINEK-KIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDI-RTQAINQKALNKAVLFELPGQVVSWMKSNSI 1721
Q L SRVEISVAC+ L DMD+ SKSDPM VL +Y E DRTE +K+ LNP F F +D+HFEE Q +YDIDS S +L DH+FLG F+ ++GELVSRR+VE+ L+ + ++ I++TC EL KE++ +Q G++LDKKD GKSDP ++ + P+ + + LVY++ + LNP+W +KLS++C G K +++ C DWN K IG + SV +L EN A + ++ R +G L N+ + E SF DYI GG EL FTV IDFTASN N P SLH+I D +G NQYE AI SVG I+QDYD + FP+ GFGAR+PP +++HCFP+ F+ NP+CAG+ GLL YRS +R+V LYGPTNFSP IRHV Q A + G +YFVLLIITDGII+DF T +II+ S LPMSIII+GVG ED+ AM+ LD D L+ G IA+ DIVQFV LRDF +++ AL KAVL ELP Q+ WM+ I
Sbjct: 9 QQGLVSRVEISVACRKLADMDLTSKSDPMCVLMMCPPGTRNYREQDRTEMLKDTLNPDFQHKFVVDFHFEEHQKVMFCLYDIDSHSTQLSDHDFLGQFESTIGELVSRRRVEAPLAK-----SPKRDSTIIITCIELQHCKEILQMQLCGSQLDKKDFLGKSDPYFEVSKPLSPVVDSSSSELLRA--QWTLVYRSAVVRKNLNPTWQPTQLKLSQMCNGNKSLILRWDCIDWNKRMKHSHIGTFYASVADILREYENSNSRGATSGAGARFQLLSRRKKPAGYLVFNRLELLIEDSFVDYIQGGCELLFTVGIDFTASNGNPATPQSLHYI---DPSGRLNQYELAITSVGEIVQDYDFRRAFPSFGFGARVPPRGDVNHCFPLTFNDSNPYCAGLAGLLQAYRSCLRSVTLYGPTNFSPIIRHVMQLAQANQSGKQYFVLLIITDGIITDFYETKLSIIEASRLPMSIIIVGVGREDFGAMEELDADNKRLQIGGMIAEADIVQFVPLRDFFRADNPNELSKSALTKAVLEELPDQLCQWMRKRGI 546
BLAST of Copine-3 vs. TrEMBL
Match: V4BR80 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_209681 PE=4 SV=1) HSP 1 Score: 486.108 bits (1250), Expect = 9.249e-162 Identity = 268/551 (48.64%), Postives = 350/551 (63.52%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQE--FNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRK--VESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLKQKNRNIS 1754
SRVEISV+C+ L+D D+ SKSDPM VLF + Y EI RTE I +NLNP F K FEIDY+FEE Q K EIYD+DS +L DH+FLG + SLGE+V ++ KL DN I++ E+ + KE+I + G+ LDKKD FGKSDP L I R+ N ++ +V++T+ I NTLNP+W F +K S LC + +R IK +C DWNS G +D IG T+V L++ +K+ + +K KK++Y NSG +T ++ ++SF DYI GG ++NFTVAIDFTASN N +P SLH++ NQY AI SVG IIQDYDSDK+FPALGFGAR+P N +SH F +NF+P NP+C G+ G+L Y +AIR V LYGPTNF+P I HV QFA DGS+YFVLLIITDGII+D+ T+DAI+ S LPMSIII+GVG+ ++ M+ LD D L + K A+RDIVQFV R+F+ +Q L K VL E+P QV S+M I P +R+ S
Sbjct: 18 SRVEISVSCRKLRDCDVISKSDPMCVLFMLDLKPHQYREIARTECINDNLNPDFVKKFEIDYYFEENQKLKFEIYDVDSDKRKLSDHDFLGKLECSLGEIVGSHGSCLKRKLVGPATDNGA-----IIVRAEEILACKEVINMHIKGSDLDKKDFFGKSDPYLTISRA-------------NEDSSYTVVHKTEFIKNTLNPTWKPFQIKGSTLCNSDHNRTIKFICNDWNSDGSVDLIGEFDTNVLELIQGHKKSFEVIYKQKKAKKKKNYKNSGIITFLNFGIEQQHSFIDYIRGGMQMNFTVAIDFTASNGNPHDPTSLHYLSPYHL----NQYAAAITSVGEIIQDYDSDKLFPALGFGARLP-NNAVSHEFALNFNPNNPYCNGVQGVLQAYYNAIRHVQLYGPTNFAPVINHVSQFAATVLDGSQYFVLLIITDGIITDYSKTVDAIVRASTLPMSIIIVGVGDANFEEMEKLDGDDVRLSSQGKYAERDIVQFVPFRNFLSNGVNVESQARLAKEVLREIPHQVRSFMSKRGIAPRPPLHRSDS 545
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne5b (copine-5 [Source:NCBI gene;Acc:103046149]) HSP 1 Score: 459.914 bits (1182), Expect = 5.199e-155 Identity = 252/541 (46.58%), Postives = 347/541 (64.14%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
++VEI+V+C+NL D D FSKSDPM VL+ + + E RTE I N LNP F + F +DY FEE+Q + ++YD+DS S L H+FLG +LGE+V S+L +K I+L+ EL + ++ +QF KLDKKD FGKSDP + YRS++ +GT F + ++T+ + NTLNP W F++ + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK+KK+ Y NSGT+TL SV+ E++F DYI GGT++NFTVAIDFTASN N SLH++ N + N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH FP+N + +NP+C GI G+L Y +++ V LYGPTNF+P + HV ++A +DGS+YFVLLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD+MD RT ++ L K VL E+P Q +S+MKS I
Sbjct: 28 TKVEITVSCRNLLDKDTFSKSDPMCVLYTQGVETKQWREFGRTEVIDNTLNPDFVRKFILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQMFCTLGEIVGSPA--SRLDKPLGGIPGKKCGTIILSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNE-----------DGT--FTICHKTEVVKNTLNPVWQSFTIPVRALCNGDFDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYM--NPYQ--MNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMSQTKEAIVNGAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYMD-RTGNHVLSMARLAKDVLAEIPDQFISYMKSRGI 548
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne5b (copine-5 [Source:NCBI gene;Acc:103046149]) HSP 1 Score: 453.366 bits (1165), Expect = 2.049e-152 Identity = 252/546 (46.15%), Postives = 347/546 (63.55%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDH-----EFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
++VEI+V+C+NL D D FSKSDPM VL+ + + E RTE I N LNP F + F +DY FEE+Q + ++YD+DS S L H +FLG +LGE+V S+L +K I+L+ EL + ++ +QF KLDKKD FGKSDP + YRS++ +GT F + ++T+ + NTLNP W F++ + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK+KK+ Y NSGT+TL SV+ E++F DYI GGT++NFTVAIDFTASN N SLH++ N + N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH FP+N + +NP+C GI G+L Y +++ V LYGPTNF+P + HV ++A +DGS+YFVLLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD+MD RT ++ L K VL E+P Q +S+MKS I
Sbjct: 28 TKVEITVSCRNLLDKDTFSKSDPMCVLYTQGVETKQWREFGRTEVIDNTLNPDFVRKFILDYFFEEKQNLRFDLYDVDSKSPDLSKHPSECNDFLGQMFCTLGEIVGSPA--SRLDKPLGGIPGKKCGTIILSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNE-----------DGT--FTICHKTEVVKNTLNPVWQSFTIPVRALCNGDFDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYM--NPYQ--MNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMSQTKEAIVNGAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYMD-RTGNHVLSMARLAKDVLAEIPDQFISYMKSRGI 553
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 442.195 bits (1136), Expect = 2.322e-148 Identity = 248/544 (45.59%), Postives = 345/544 (63.42%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAF--VLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF---ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRN-GNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
++VE+SV+C +L D D+ SKSDP VLFQE +++++E+ RTET NNLNPVF F++DYHFEE Q K ++D D S++L +H+FLG+F +LG +VS +K+ L+ + I +T ELS ++ +I L G KLDKKD FGKSDP L+ ++ + ++LV++T+ I NTL+P W F+V L LC G++ +++C D+++ G DFIG T+V + E Q E + +K+ KK++Y NSG + L + +YSF DYI GG +L FTV IDFTASN N P SLH+I N N+Y +AI +VG IIQDYDSDKMFPALGFGA++PP+ ++SH F INF P NPFCAG+ G++ Y + + + YGPTNF+P I HV +F ALQ ++YF LLIITDG+ISD + T AI+ + LPMSIIIIGVGN D++AM+ LD D +LR+ + A RDIVQFV RDF + ++ L K+VL ELP QV + K ++ P
Sbjct: 22 TKVELSVSCTSLLDRDVASKSDPFCVLFQEVDSNWVELGRTETAVNNLNPVFGDKFQVDYHFEEVQKLKFALFDEDKCSSQLYEHDFLGEFVCTLGVIVSNKKLHRPLT--LANGKPAGKGAITITAQELSDNR-IITLSMCGRKLDKKDFFGKSDPYLEFHKQGE-------------DGKWMLVHRTEVIKNTLDPVWKPFTVPLISLCNGDEVLYSQVLCYDYDNDGGHDFIGEFLTTVTKMSEAQNSVEVEFECINPKKQKKKKNYKNSGIIILKSCKITRDYSFLDYILGGCQLMFTVGIDFTASNGNPREPSSLHYI--NPLG--SNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFDPTNPFCAGVEGIVQAYSTCLPHLRFYGPTNFAPIINHVARFASQALQQDTAAQYFTLLIITDGVISDMDETRHAIVQAAKLPMSIIIIGVGNADFAAMEFLDGDSSVLRSYTGEEAVRDIVQFVPFRDFRNAP-----KETLAKSVLAELPQQVTQYFKQRNLSP 540
BLAST of Copine-3 vs. Ensembl Cavefish
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498]) HSP 1 Score: 441.81 bits (1135), Expect = 3.644e-148 Identity = 247/541 (45.66%), Postives = 340/541 (62.85%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
++VEI+V+C+NL D D FSKSDP+ VL+ + N + E RTE I N LNP F + F +DY FEERQ + ++YD+DS S+ L H+FLG + +LGE+V + S+L +K I++ EL++ +E + +QF G KLDKKD FGKSDP L YRS++ +GT F + ++T+ + NTLNP W F + + LC G+ D DFIG TS L Q + + +IN +KK KK+ Y NSGT+TL V + +F DYI GGT++NFTVAIDFTASN N P SLH++ N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH F +N +PQNP+C GI G++ Y ++++V LYGPTNFSP I HV ++A +DGS+YFVLLIITDG+ISD T ++I++ S LPMSIII+GVG ++ AM LD D+ + + + A+RDIVQFV RD++D RT ++ L K VL E+P Q +S+MK+ I
Sbjct: 30 TKVEITVSCRNLLDRDTFSKSDPICVLYTQGIGNKEWREFGRTEVIDNTLNPEFVRKFILDYFFEERQNLRFDLYDVDSKSSNLSKHDFLGQAQCTLGEIVG--SMGSRLEKPLGGIPGKKCGTIIVKAEELNNCRESVMMQFCGNKLDKKDFFGKSDPFLVFYRSNE-----------DGT--FTICHKTEVVKNTLNPVWQAFKIPVRALCNGDYD--------------SHDFIGEFSTSYRELSRGQSQFNVYEVINPKKKGKKKKYLNSGTVTLLSFLVDIDVTFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMSPYQL----NAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFALNGNPQNPYCNGIDGVMEAYYQSLKSVQLYGPTNFSPVINHVARYAASVKDGSQYFVLLIITDGVISDMAQTKESIVNASCLPMSIIIVGVGPAEFDAMVELDGDEVRISSRGRYAERDIVQFVPFRDYID-RTGNHILSMARLAKDVLAEIPDQFLSYMKTRGI 536
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne4a (copine-4-like [Source:NCBI gene;Acc:111188392]) HSP 1 Score: 429.098 bits (1102), Expect = 3.062e-143 Identity = 237/546 (43.41%), Postives = 338/546 (61.90%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGH---CFTSVNHLLENQRKNEAFVLINEK-KIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQ---YRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRN-GNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
++VE+ V CK + D D SK DP ++ + + +LE+DRTE I++ NP F+K F +DY+FEE Q + E+YD++SS N + + + LG + +LG++VS+RK+ L + +NT I +T EL+ + + + L F KLD KD F KSDP L+IYR +D +GT+ LVY+T+ +MN LNP W F L+ LC G+ +R++K DW+S+GK DFIG F + ++ K + IN K K KK++Y NSG + LN+ + +SF DYI GG ++ FTVAIDFTASN + N SLH+I N+Y A+++VG I QDYDSDKMFPALGFGARIPP+ ++SH F +NF+ NP CAGI G++ Y++ + + LYGPTN +P I+ V A + R+ +YF+LLI+TDG+I+D T +AI+ S LPMSIII+GVGN D++ M LD D G+LR+ + RDIVQFV R+F + + AL K+VL E+P QVV + S I P
Sbjct: 21 TKVELRVTCKGISDRDALSKPDPCVIIKMQSHGQWLEVDRTEVIRSCCNPTFSKVFTLDYYFEEVQRLRYELYDMNSSHNGMREADCLGAVECTLGQIVSQRKLCRALLKQ---SNTVGKSTITITAEELTGNDDYVELSFSARKLDDKDFFSKSDPFLEIYRVND-----------DGTQQ--LVYRTETVMNNLNPVWKTFKTSLNCLCSGDHERILKCTVWDWDSNGKHDFIGEFEATFKEMRGAIDG--KQVQWECINPKYKTKKKNYRNSGIVILNQCKIIKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYI----HPYQPNEYLKALVAVGEICQDYDSDKMFPALGFGARIPPDFKVSHDFAVNFNDDNPECAGIQGVVEAYQNCLPKIQLYGPTNIAPIIQKVANSASEEEHTREAMQYFILLILTDGVITDMADTREAIVHASHLPMSIIIVGVGNADFTDMQILDGDDGILRSPKGEPVLRDIVQFVPFRNF-----KHASPAALAKSVLAEVPSQVVDYYNSKGIKP 539
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 431.795 bits (1109), Expect = 5.208e-145 Identity = 242/548 (44.16%), Postives = 342/548 (62.41%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAF---VLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYR---DGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRN-GNKIAQRDIVQFVALRDFMDIRTQAINQKA---LNKAVLFELPGQVVSWMKSNSIIP 1727
SRV+++++C++L D D+ +KSDP VLF E + ++E+ RTETIKN L P F++ ++Y FEE Q K ++D D+ S +LVDH+FLG+ +LG++VS R + L + D+ I ++ E++ ++ +I L G KLDK DLFGKSDP L+IY+ S +GT ++LV++T+ + NTL+P+W F++ L LC G+ ++ I VC DW+ G D IG + ++ L E E + N+KK KK+SY NSG + + +Y+F DYI GG +L+FTV IDFTASN N + SLH+I N Y AI +VG IIQDYD+DK+FPALGFGA++PP+ ++ H F +NF+P NPFC GI G++ Y ++ + LYGPTNFSP I HV FA S+Y+VLLIITDG+ISD EAT +AI+ S LPMS+II+GVGN D+ AM+ LD D +L + A RDIVQFV R F + IN+ A L K+VL ELPGQVV + + ++ P
Sbjct: 19 SRVQLTISCRSLLDRDMLTKSDPFCVLFIECDKQWMEVARTETIKNTLCPDFSRKLVMEYRFEEVQKLKFALFDEDAPSAKLVDHDFLGEITSTLGQIVSHRTLTRPLLMQ--DDRPAGRGTITISAEEITDNR-IITLSMAGRKLDKMDLFGKSDPYLEIYKQSP-----------DGT--WMLVHRTEVVRNTLDPTWKPFTLHLQVLCNGDLEKNINAVCYDWDRHGSPDLIGEFYANIIRLKEATGSMEVVEFECINNKKKQKKKSYKNSGIIICKSCKISRDYTFLDYIFGGCQLHFTVGIDFTASNGNPRDASSLHYISPTGM----NDYLAAIWAVGQIIQDYDTDKLFPALGFGAQLPPDCKVHHDFALNFNPSNPFCTGIEGIVAAYHFCLQNIRLYGPTNFSPIINHVASFAHTASGSASASEYYVLLIITDGVISDMEATREAIVKASRLPMSVIIVGVGNADFEAMEVLDSDDRVLTAPSGEAATRDIVQFVPFRQFRSVDRLLINKAAKEELAKSVLAELPGQVVQYFRQRNLSP 546
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007777.1 (pep scaffold:Pmarinus_7.0:GL477373:3581:22444:1 gene:ENSPMAG00000006999.1 transcript:ENSPMAT00000007777.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 366.311 bits (939), Expect = 6.309e-120 Identity = 211/511 (41.29%), Postives = 314/511 (61.45%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTV------AIDFTASNENNPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQF---ALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRN-GNKIAQRDIVQFVALRDF 1619
S+VE++V+CK+L D D+ SKSDP+ V+ E ++ E+DRTE I+N P F+K +IDY FE+ Q + +YDID+ + L D +FLG + +L ++VS +K+ L + + I + +E+ ++ ++ LQ LDKKD+FGKSDP L+ ++ +D +GT + +V++T+ I N LNP+W FS+ L LC G+ +R +++VC D++S G D IG T+V +L + ++ F +I+ EKK KK++Y SG + + + EYSF DYI GG ++NFTV + + N ++LH IP P A+ S I + DK+FPA GFGA+IPPN ++SH FP+NF+P NP+C G+ G+++ Y+ + V LYGPTNFSP I HV +F ALQ ++YFVLLI+TDG+ISD + T A++ S LPMS+II+GVGN D+SAM+ LD D G+L+ + A RDIVQFV RDF
Sbjct: 38 SKVELTVSCKDLLDKDVGSKSDPLCVVLIEAGGTWSEVDRTEQIQNCQEPAFSKRLQIDYCFEQVQKLRFGVYDIDNKTYDLTDDDFLGQLECNLAQVVSSKKMTRPLLLK--NGKPAGKGQITIVADEIKDNR-VLALQVDARNLDKKDMFGKSDPYLEFFKMAD-----------DGT--WQMVHRTEVIKNNLNPTWRPFSIPLQALCNGDLERDVRVVCYDYDSDGSHDLIGEFKTNVKNLQQAEKGQVEFAVIHPEKKKKKKNYKGSGLVIVKSCRTEVEYSFLDYIMGGCQINFTVRSALRSCLTLGDIHRINLLTLH-IPW-----PLLPLNNALSSFNGIKSHHLQDKLFPAFGFGAQIPPNWQVSHEFPLNFNPANPYCNGVQGIVDMYKVCLPQVRLYGPTNFSPIINHVARFAAAALQQPAATQYFVLLIVTDGVISDMDETRLAVVQASRLPMSLIIVGVGNADFSAMEFLDGDGGVLKAPSGEPAARDIVQFVPFRDF 526
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000748.1 (pep scaffold:Pmarinus_7.0:GL477446:179420:193439:1 gene:ENSPMAG00000000673.1 transcript:ENSPMAT00000000748.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 246.899 bits (629), Expect = 7.470e-76 Identity = 145/396 (36.62%), Postives = 214/396 (54.04%), Query Frame = 3
Query: 564 KDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEA-FVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNE--NNPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHV----QQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRN-GNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
+D FGKSDP L++Y+ + + LVY+T+ NTLNP W + L LC G + IK+VC DWN +G+ + IG C +V L + + N F L+ +K +Y NSG L + ++ +Y+F DYI GG +L F++AIDFTASN+ + SLH ND NQY I +VG +Q YD+DK FPA GFGA++P +++S FP+ + NP C G+ L+ Y+S + V L P N +P I V ++ Q + +Y +L IITDG + D AT +AI+ S LP+SI+++GVG+ D+ + LD D +L + A RDIVQFV DF + ++ V+ E+P QV + + P
Sbjct: 1 QDWFGKSDPFLELYKQT-------------SIGKWKLVYRTEVHKNTLNPRWKNIVLNLQSLCDGNIAKPIKVVCADWNRNGRSNPIGECIVTVMQLNQAKLNNTVMFDLVLPGNVKNSNYKNSGQLVVVLCTICRQYTFLDYIRGGCKLQFSMAIDFTASNKPPSQLDSLHHTGFND----ANQYLMVIRAVGGTLQYYDADKQFPAYGFGAQLPSEEKVSQDFPLTLNANNPNCDGVQALIKAYKSCLTKVKLSEPANLAPVINRVATAAKRIKFQSKLAHEYHILFIITDGEVKDMPATREAIVQASKLPLSIVLVGVGSNDFRDLVELDSDDAILTAPSGENAFRDIVQFVPYLDFARDPVEKFLEQ-----VMEEIPHQVEQYFHQMDLQP 374
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 221.09 bits (562), Expect = 5.637e-68 Identity = 121/242 (50.00%), Postives = 161/242 (66.53%), Query Frame = 3
Query: 1020 VAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHV---QQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRN-GNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
V I F+ASN + +P SLH I N+Y A+ +VG +IQDYD+DK FPALGFGA++PP E+SH F +NF+P NPFC G+ G++ Y + + V LYGPTNFSP I HV A Q ++YFVLLI+TDG+ISD + T A++ S LPMS+II+GVG+ D+SAM+ LD D G+L+ + A RDIVQFV RDF + ++AL KAVL E+PGQVV++ K S+ P
Sbjct: 1 VGIHFSASNGDPRDPSSLHHISPTG----TNEYLAAVWAVGQVIQDYDADKQFPALGFGAQLPPEWEVSHEFALNFNPLNPFCTGVEGIVQAYMACLPQVRLYGPTNFSPIINHVARFAAAAAQQPAATQYFVLLIVTDGVISDMDETRLAVVQASRLPMSLIIVGVGSADFSAMEFLDGDGGVLKAPSGEPAARDIVQFVPFRDFRNAP-----KEALAKAVLAEVPGQVVTYFKQCSLAP 233
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 214.157 bits (544), Expect = 4.063e-65 Identity = 113/263 (42.97%), Postives = 165/263 (62.74%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFN-NSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKK 905
++VE+SV+C NL D DI SKSDP+ VL+ E +++E+ RTE++KN+LNPVF F+IDYHFEE Q + IYD+DS S RL DH+FLGD +LG++VS +K+ L + D +I + E+ ++ L L F G KLDKKD FGKSDP L+ ++ D +G+ ++LV++T+ ++NTLNPSW F++ + LC G+ DR +++ C D++S G DFIG TSV +LE Q + +N KK
Sbjct: 6 TKVEMSVSCTNLLDKDITSKSDPLCVLYMECGPGNWMELGRTESMKNDLNPVFAHKFQIDYHFEEVQKLRFAIYDLDSPSKRLQDHDFLGDLTLTLGQVVSSKKLSRALVLK--DGRPAGKGIIQVLAEEMKDNRHLQLL-FEGIKLDKKDFFGKSDPYLEFFKKGD-----------DGS--WVLVHRTEVVLNTLNPSWRPFTLAVQSLCGGDLDRSVRVTCYDYDSDGGHDFIGEFQTSVTQMLEAQSGKQVRTCMNVKK 252
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO44352 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW53]) HSP 1 Score: 444.121 bits (1141), Expect = 9.160e-150 Identity = 254/545 (46.61%), Postives = 338/545 (62.02%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYN-NSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQ---YRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKA-LNKAVLFELPGQVVSWMKSNSIIP 1727
++VEISV+C+NL DMD+FSKSDPM V+F + + E RTE I NNLNP F K F I Y FEE Q + ++YDID S+RL DH+F+G+ + +LG +V + + + L C E+S K++ LQF G KLDKKD FGKSDP L YR N +F V++T+ + NTLNP+W FSV LC G+ DR I++ C DW+ G D IG T++ L N N F L N KK K+ NSGT+ L ++ ++ + +F D+I GGT+++F VAIDFTASN N N SLHF+ N + NQY A+ SVG+I QDYDSDK+FPA GFGAR+PPN E+SH F +N +PQNPFC + G++++Y +I+ V LYGPTNFSP IR A + + G +YFVLLI+TDGIISD E T AI+D + LP+SIII+GVG D+ AM+ LD D+ L + ++A+RDIVQFV RD++D I A L K VL ELP Q+ +MK +I P
Sbjct: 12 TQVEISVSCRNLADMDVFSKSDPMVVMFTQGMGTKEWREFGRTEVIMNNLNPDFVKKFTIHYFFEEIQKLRFQVYDIDKKSSRLQDHDFIGEIECTLGSIVGENGGQLEKA---------------LLCEEVSQCKDVATLQFRGHKLDKKDFFGKSDPFLVFYRC-------------NEDNSFTAVHRTEVVKNTLNPTWKPFSVPARALCNGDIDRSIRIECYDWDRDGSHDLIGIFSTTLRELTSN--PNLTFELKNPKKQAKKKSYKNSGTIILLQSKLEQQPTFLDFIKGGTQISFIVAIDFTASNGNPQNSNSLHFL--NPYE--PNQYVKALTSVGAICQDYDSDKLFPAFGFGARLPPNWEVSHEFALNGNPQNPFCERVEGVISSYFHSIQRVQLYGPTNFSPIIRRTVALAKESERQKPGEEYFVLLILTDGIISDMEQTKAAIVDAASLPVSIIIVGVGGADFEAMEELDGDEVRLSSRGRLAERDIVQFVPFRDYLDKCYGDITSGARLAKDVLEELPDQLTDYMKKRNIKP 522
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO39500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9X6]) HSP 1 Score: 424.861 bits (1091), Expect = 2.755e-142 Identity = 237/541 (43.81%), Postives = 335/541 (61.92%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVL-FQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQ-YRDGS--KYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSI 1721
++VE+ ++C+ L D D SKSDP+AVL Q+ + + E RTE +KNNLNP F+K +DY+FE Q K ++D+D+++ +L D +FLG + +LG++VS++ L + R+ I + E+ + E++ L F T LD KD GKSDP L++ K LLV++T+ I N LNP+W FS+ + LC + D I++ C D++ G D IG TS+ LLE ++ LIN +KK KK+ Y NSG L ++ V + +F DY+ GG ++NFTV +DFTASN N P SLH+I N + N+Y A++SVG + QDYDSDK+FPA GFGA+IPPN ++SH F +NF+P NP+C GI G++ Y++ IR V LYGPTN SP I HV FA + +DG+ YFVLL+ITDG++SD EAT AI+ S LPMS+II+GVG+ D++ M+ LD D+G LR G++ A+RDIVQFV RDF +TQ L K VL E+P Q + S I
Sbjct: 6 TKVELHISCRGLLDKDAMSKSDPIAVLHMQDNSGRWYEFSRTERVKNNLNPDFSKAISVDYYFELVQKLKFSVFDVDNATKQLDDDDFLGSIECTLGQIVSKKSFTKHLEIK-----GRQVGTITIYAEEMKGANEIVKLTFRATNLDNKDFMGKSDPFLELL-------------KLKPDGGTLLVHRTEVIKNNLNPTWKVFSLPIQSLCSADYDATIRIDCHDYDGDGSHDLIGIANTSLRQLLELRQSGSGLDLINPKKKAKKKKYVNSGVLYISGCEVIHHNTFLDYVMGGCQINFTVGVDFTASNGNPSTPQSLHYI--NPYE--PNEYVNALVSVGEVCQDYDSDKLFPAFGFGAKIPPNFQVSHEFALNFNPSNPYCEGIPGVVAAYQACIRQVQLYGPTNASPIINHVASFAQRAAQDGTAGAYFVLLLITDGVLSDMEATKLAIVRASRLPMSLIIVGVGSADFTDMNELDADEGTLRAGHERAERDIVQFVPFRDF---KTQP--PAMLAKHVLAEVPKQAQEYFNSRGI 519
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO45927 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRD6]) HSP 1 Score: 389.037 bits (998), Expect = 2.020e-128 Identity = 229/571 (40.11%), Postives = 325/571 (56.92%), Query Frame = 3
Query: 51 KIYYNQKYSFNKAEMNSIQDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAF---VLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGS----KYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLKQ 1736
+ Y N Y + + SRV+++++CKNL D D+ SKSDP+ V+ +N++ E+ RTE ++N LNP F+ +DY FEE Q K +YDIDS+S L + +FLG+ + +LG+LVS L ++ S K + D FGKSDP L+ R+ K +G+ F++V++T+ + N LNP W + +LC G+ DR++K+ C DW+ G D IG T++ L Q+ + +K+ KK++Y NSG + L+ V SF D+I GG ++NFTV IDFT SN N +P SLH+I N +A N+Y A+ +VG IIQDYDSDK+FPA GFGA++PPN +SH F +NF+ NPFCAG+ GL+ Y+ +R V LYGPTN +P I +V +A Y++LLI+TDG+ISD + T AI+ S LPMSIII+GVG+ D+ M+ LD D GLLR+ AQRDIVQFV R F ++ + AL K VL E+PGQV + K +I P Q
Sbjct: 2 QAYRNCPYPTSGPGAPPATAQCLSRVQLNISCKNLIDKDVMSKSDPLVVVMMLRHNNWEEVGRTERLENTLNPNFSTTIVVDYFFEELQKLKFMVYDIDSASGSLKNADFLGEMQCTLGQLVSSATYTHNL--------------------KIPSGKP---------AGNMTDFFGKSDPYLEFSRA-----------KEDGS--FVVVHRTEVVSNNLNPKWKPIHISSQQLCNGDYDRVLKVNCYDWDDDGSHDLIGTFTTTLRELSTCQQGGAELQWPCINEKKRKKKKNYKNSGVIFLSSCQVVRVASFLDFIQGGCQINFTVGIDFTGSNGNPASPTSLHYI--NPYA--PNEYCQALTAVGEIIQDYDSDKLFPAFGFGAKVPPNNMVSHQFALNFNHTNPFCAGLQGLIEAYQQCVRQVTLYGPTNIAPIISNVAMYAQAAAQQPYASLNYYILLILTDGVISDMDQTKRAIVQASGLPMSIIIVGVGSADFEMMEELDADDGLLRSEGSTAQRDIVQFVPFRKFKNLSS-----AALAKEVLAEVPGQVTGYYKMRNISPGGQ 521
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO49902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF64]) HSP 1 Score: 214.542 bits (545), Expect = 1.105e-62 Identity = 144/475 (30.32%), Postives = 233/475 (49.05%), Query Frame = 3
Query: 123 RVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDS-SSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKK-RSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNENNPI--SLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQ--YRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAM 1529
++EI V C +L +D FSKSDP+ VL + + E RTE++ NNL+P F ++F ++ + +YD+ + +S L H+F+G + + L+S + D TR I L E+ +S + Q G L+K+ L K D ++ R LP + VY+++ + TL+P W F + L +LC E R + C ++SSG I V HL+ R + L+ +K +K R +G+L ++ V +S DYI GG ++ AIDFT SN + SLH + QN+Y A+ ++G ++ YD DK P FGA+ I +CF +N P + I L++TY ++ + L GPT P I+ + +A + +D Y V ++I DG+ +D + T + II S LP+SI+++GVG D++AM
Sbjct: 1 KIEIFVQCTDLVQLDKFSKSDPLCVLSVKKLGHWTEFGRTESLPNNLSPKFVESFVLEPSASLYPRLRFSLYDLANFTSKDLRKHDFIGCTEIDIDSLLSAESPYVRTLRVPGDIQTRG--FIKLFYEEVHTSLTNVRFQISGVNLEKRSLLSKWDVFFELER------LLPGGF-------YHPVYRSEIVARTLDPRWSPFDIYLQKLCNEEVTREAVISCWHYSSSGANTLIASARCPVGHLI--NRSIKVLQLVKPQKTQKARRAGTAGSLRIDHCHVDKHFSLVDYIRGGCDVTIACAIDFTLSNGDPSCRSSLHTLS----CLYQNEYIGALRALGPVLMHYDEDKQIPTFAFGAK--SKHGIPYCFALNGDESEPEISSIETLIDTYTRSLTTIKLGGPTYLVPVIKRLADYATRELSQDSQHYLVAMVIMDGVANDLDDTKEQIIQVSGLPLSIVVVGVGPADFTAM 452
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO26801 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TB16]) HSP 1 Score: 122.094 bits (305), Expect = 7.364e-31 Identity = 80/203 (39.41%), Postives = 116/203 (57.14%), Query Frame = 3
Query: 564 KDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAF---VLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYD 1157
KD FGKSDP L+ R+ K +G+ F++V++T+ + N LNP W + +LC G+ DR++K+ C DW+ G D IG T++ L Q+ + +K+ KK++Y NSG + L+ V SF D+I GG ++NFTV IDFT SN N +P SLH+I N +A N+Y A+ +VG IIQDYD
Sbjct: 106 KDFFGKSDPYLEFSRA-----------KEDGS--FVVVHRTEVVSNNLNPKWKPIHISSQQLCNGDYDRVLKVNCYDWDDDGSHDLIGTFTTTLRELSTCQQGGAELQWPCINEKKRKKKKNYKNSGVIFLSSCQVVRVASFLDFIQGGCQINFTVGIDFTGSNGNPASPTSLHYI--NPYA--PNEYCQALTAVGEIIQDYD 291 HSP 2 Score: 62.003 bits (149), Expect = 1.909e-10 Identity = 32/98 (32.65%), Postives = 55/98 (56.12%), Query Frame = 3
Query: 486 IVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIK 779
+ +T E++ + + + + F KLD KD FGKSDP L+ R+ K +G+ F++V++T+ + N LNP W + +LC G+ DR++K
Sbjct: 22 MTVTTEEVAGTNDEVQMVFRAQKLDNKDFFGKSDPYLEFSRA-----------KEDGS--FVVVHRTEVVSNNLNPKWKPIHISSQQLCNGDYDRVLK 106
BLAST of Copine-3 vs. Ensembl Medaka
Match: CPNE8 (copine 8 [Source:NCBI gene;Acc:101158741]) HSP 1 Score: 468.003 bits (1203), Expect = 2.900e-158 Identity = 252/541 (46.58%), Postives = 348/541 (64.33%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
++VEI+V+C+NL DMD FSKSDP+ VL+ + N + E RTE I N LNP F + F +DY FEERQ ++++YD+DS S L H+FLG +LGE+V + S+L +K I++ EL++ +E + +QF G KLDKKD FGKSDP L YRS++ +GT F + ++T+ + NTLNP W F + + LC G+ DR IK+ DW+ G DFIG TS L Q + + ++N +KK KK+ Y NSGT+TL V E +F DYI GGT++NFTVAIDFTASN N P SLH++ N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH F +N +PQNP+C GI G++ Y +++V LYGPTNF+P I HV ++A +DGS+YFVLLIITDG+I+D T +AI++ S LPMSI+I+GVG ++ AM LD D+ + + ++A+RDIVQFV RD+MD RT ++ L K VL E+P Q +S+M++ I
Sbjct: 24 TKVEITVSCRNLLDMDTFSKSDPICVLYTQAIGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERQNLRLDLYDVDSKSANLSKHDFLGQAYCTLGEIVG--SLGSRLEKPLGGIPGKKCGTIIVKAEELNNCRESVMMQFCGNKLDKKDFFGKSDPFLIFYRSNE-----------DGT--FTICHKTEVVKNTLNPVWQAFKIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFSTSYRELSRGQSQFNVYEVVNPKKKGKKKKYLNSGTVTLLSFLVDIEVTFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMSPYQL----NTYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFALNGNPQNPYCDGIDGVMEAYYQTLKSVQLYGPTNFAPVINHVARYAASVKDGSQYFVLLIITDGVITDMALTKEAIVNASGLPMSILIVGVGPAEFDAMVELDGDEVRISSRGRLAERDIVQFVPFRDYMD-RTGNHVLSMARLAKDVLAEIPDQFLSYMRTRGI 544
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5a (copine-5 [Source:NCBI gene;Acc:101166794]) HSP 1 Score: 463.381 bits (1191), Expect = 2.173e-156 Identity = 250/543 (46.04%), Postives = 348/543 (64.09%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNS--YLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRS-YNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
++VEI+V+C+NL D D FSKSDPM VL+ + S + E RTE IKN LNP F + + +DY FEE+Q + ++YDIDS S L H+FLG +LGE+V S+L + I+L+ EL + ++ +QF KLDKKD FGKSDP + YRS++ +GT F + ++T+ + NTLNP W FS+ + LC G+ DR IK+ DW+ G DFIG TS L Q ++ + ++N KK K+ Y NSGT++L SV+ E++F DYI GGT+++FTVAIDFTASN N SLH++ N + N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH FP+N + +NP+C G+ G+L Y +++ V LYGPTNF+P + HV ++A DGS+YF+LLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD+MD RT ++ L K VL E+P Q++S+MKS +I P
Sbjct: 28 TKVEITVSCRNLLDRDTFSKSDPMVVLYTQGVESKQWREFGRTEVIKNTLNPDFVRKYILDYFFEEKQNLRFDVYDIDSKSPDLGKHDFLGQVYCTLGEIVGSPA--SRLEKPLGGIPGKTCGTIILSAEELGNCRDYATMQFCANKLDKKDFFGKSDPFMVFYRSNE-----------DGT--FTICHKTEVVKNTLNPMWQPFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFSTSYKELCRGQSESNVYEVVNAKKKLKKKRYINSGTVSLLSFSVESEHTFLDYIKGGTQIHFTVAIDFTASNGNPSQSTSLHYM--NPYQ--MNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVENPYCNGMEGILEAYHQSLKLVQLYGPTNFAPVVNHVARYAAAVEDGSQYFILLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYMD-RTGNHVLSMARLAKDVLAEIPDQLISYMKSRAIKP 550
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5b (copine-8 [Source:NCBI gene;Acc:101170754]) HSP 1 Score: 459.914 bits (1182), Expect = 3.948e-154 Identity = 250/541 (46.21%), Postives = 346/541 (63.96%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEF--NNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSI 1721
++VEI+V+C++L D D FSKSDPM VL+ + + E RTE I N LNP F + + +DY FEE+Q + ++YD+DS S L H+FLG +LGE+V S+L +K I+L+ ELS+ ++ +QF KLDKKD FGKSDP + YRS++ +GT F + ++T+ + NTLNP W F++ + LC G+ DR IK+ DW+ G DFIG TS L Q + + +IN +KK+KK+ Y NSGT+TL SV+ E++F DYI GGT++NFTVAIDFTASN N SLH++ N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH FP+N + +NP+C GI G+L Y +++ V LYGPTNF+P + HV ++A +DGS+YFVLLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD+MD RT ++ L K VL E+P Q +S+MKS +
Sbjct: 86 TKVEITVSCRHLLDKDTFSKSDPMCVLYTQGVETKQWREFGRTEVIDNTLNPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQVFCTLGEIVG--SPASRLEKPLGGIPGKKCGTIILSAEELSNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNE-----------DGT--FTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGDFTTSYRELARGQSQFNVYEVINTKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQL----NAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNLENPYCNGIEGILEAYHESLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRVSSRGKLAERDIVQFVPFRDYMD-RTGNHVLSMARLAKDVLAEIPDQFISYMKSRGV 606
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5a (copine-5 [Source:NCBI gene;Acc:101166794]) HSP 1 Score: 457.603 bits (1176), Expect = 4.786e-154 Identity = 250/548 (45.62%), Postives = 348/548 (63.50%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNS--YLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDH-----EFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRS-YNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRT--QAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
++VEI+V+C+NL D D FSKSDPM VL+ + S + E RTE IKN LNP F + + +DY FEE+Q + ++YDIDS S L H +FLG +LGE+V S+L + I+L+ EL + ++ +QF KLDKKD FGKSDP + YRS++ +GT F + ++T+ + NTLNP W FS+ + LC G+ DR IK+ DW+ G DFIG TS L Q ++ + ++N KK K+ Y NSGT++L SV+ E++F DYI GGT+++FTVAIDFTASN N SLH++ N + N Y A+ +VG IIQDYDSDKMFPALGFGA++PP+ +SH FP+N + +NP+C G+ G+L Y +++ V LYGPTNF+P + HV ++A DGS+YF+LLIITDG+ISD T +AI++ + LPMSIII+GVG ++ AM LD D + + K+A+RDIVQFV RD+MD RT ++ L K VL E+P Q++S+MKS +I P
Sbjct: 28 TKVEITVSCRNLLDRDTFSKSDPMVVLYTQGVESKQWREFGRTEVIKNTLNPDFVRKYILDYFFEEKQNLRFDVYDIDSKSPDLGKHPTDLNDFLGQVYCTLGEIVGSPA--SRLEKPLGGIPGKTCGTIILSAEELGNCRDYATMQFCANKLDKKDFFGKSDPFMVFYRSNE-----------DGT--FTICHKTEVVKNTLNPMWQPFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFSTSYKELCRGQSESNVYEVVNAKKKLKKKRYINSGTVSLLSFSVESEHTFLDYIKGGTQIHFTVAIDFTASNGNPSQSTSLHYM--NPYQ--MNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVENPYCNGMEGILEAYHQSLKLVQLYGPTNFAPVVNHVARYAAAVEDGSQYFILLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYMD-RTGNHVLSMARLAKDVLAEIPDQLISYMKSRAIKP 555
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne8 (copine-8 [Source:NCBI gene;Acc:101173626]) HSP 1 Score: 454.907 bits (1169), Expect = 4.445e-153 Identity = 244/541 (45.10%), Postives = 342/541 (63.22%), Query Frame = 3
Query: 120 SRVEISVACKNLKDMDIFSKSDPMAVLFQE--FNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN--EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKA-LNKAVLFELPGQVVSWMKSNSI 1721
++VE++V+C+NL D D FSKSDP+ VL+ + N + E RTE I N LNP F + F +DY FEERQ + ++YD+D S+ L H+FLG +LGE+V + S+L + +K I++ ELS+ +E + LQF G KLDKKD FGKSDP L YRS N ++ + ++T+ + NTL+P W F + + LC G+ DR IK+ DW+ G DFIG TS + +Q + + ++N +K KK+ Y NSGT+TL V E SF DYI GGT++NFTVAIDFTASN N P SLH++ N Y A+ +VG IIQDYDSDK+FPALGFGA++PP+ +SH FP+N +PQNP+C GI G+L Y ++++V LYGPT+FSP I HV ++A DGS+YF+LLII+DG+I+D T ++I++ + LPMSIII+GVG ++ M LD D+ + + + A+RDIVQFV RD++D R I A L K VL E+P Q +S+M++ I
Sbjct: 19 TKVELTVSCRNLLDRDTFSKSDPICVLYTQGIANREWREFGRTEVIDNTLNPDFVRKFILDYFFEERQNLRFDLYDLDCKSDNLSKHDFLGQAFCTLGEIVG--SLGSRLEKPLIGIPGKKCGTIIVRAEELSNCRESVMLQFCGNKLDKKDFFGKSDPFLVFYRS-------------NEDGSYTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRSIKVEVYDWDRDGGHDFIGEFSTSYREMSRSQSQFHIYEVLNPKKKGKKKKKYLNSGTVTLLSCLVDTELSFLDYIRGGTQINFTVAIDFTASNGNPSQPTSLHYMSPYQL----NDYAMALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPQNPYCNGIDGVLEAYYQSLKSVRLYGPTHFSPVINHVARYASAVTDGSQYFILLIISDGVITDMAQTKESIVNAASLPMSIIIVGVGPAEFDEMIELDGDEERISSQGRYAERDIVQFVPFRDYIDRRGNHILSMARLAKEVLAEIPDQFLSYMRTRGI 540
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000009884.1 (SMESG000009884.1) HSP 1 Score: 1172.15 bits (3031), Expect = 0.000e+0 Identity = 578/582 (99.31%), Postives = 581/582 (99.83%), Query Frame = 3
Query: 93 MNSIQDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNENNPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLKQKNRNISPQFTGDAXXXXXXMSDPFALNLSHSMQN 1838
MNSIQDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNENNPISLHFIPQNDFAGPQNQYE AILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAV+LYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNED+SAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLKQKNR+ISPQFTGDAPPPPYPMSDPFALNLSHSMQN
Sbjct: 1 MNSIQDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNENNPISLHFIPQNDFAGPQNQYEIAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVVLYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDFSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLKQKNRSISPQFTGDAPPPPYPMSDPFALNLSHSMQN 582
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000009884.1 (SMESG000009884.1) HSP 1 Score: 870.922 bits (2249), Expect = 0.000e+0 Identity = 422/424 (99.53%), Postives = 423/424 (99.76%), Query Frame = 3
Query: 93 MNSIQDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNENNPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQ 1364
MNSIQDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNENNPISLHFIPQNDFAGPQNQYE AILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAV+LYGPTNFSPSIRHVQQ
Sbjct: 1 MNSIQDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLINEKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNENNPISLHFIPQNDFAGPQNQYEIAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVVLYGPTNFSPSIRHVQQ 424
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000009873.1 (SMESG000009873.1) HSP 1 Score: 748.429 bits (1931), Expect = 0.000e+0 Identity = 363/545 (66.61%), Postives = 446/545 (81.83%), Query Frame = 3
Query: 105 QDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSRRKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLFGKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN-EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASNEN--NPISLHFIPQNDFAGPQNQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPL 1730
QD L ++VE+S+AC++LKDMD+FSKSDPMAVLFQ+ N + E+ RTE KNNLNP+F+K FE+DYHFEERQ+ K+EIYD D SS+RL D +F G ++FSLGELVSRRK+E+ L+ + T K Q+I+LT +E+ + KEL+ LQ GTKLDKKD FGKSDP+++IYRS++PI F+ ++ N NF L+Y+++PIMNTLNPSWP+F++KL +LC G+KD++IK+VC DWNS G DFIG CFTSVN L+ N K + F LIN +K++KK+ Y NSGTL++NK+ ++ +YSF D+ISGGTELNFTVAIDFT SN N NP SLH+IP +G NQYETAI+SVGSIIQDYDSDKMFPALGFGARIPPN EISHCFPI FSPQNPFC+G+ GLL TYRSAIR V L GPTNFSPSIRHVQQFA Y+DGSKYFVLLIITDGII+D TI+AIIDCS+LP+SIIIIGVGNED+SAMD+LDCDKG L++G+K+A+RDIVQFV +R+FM + INQ AL+KAVL ELP QV SWMK N IPL
Sbjct: 5 QDTLITKVELSIACRDLKDMDVFSKSDPMAVLFQKLQNQFFEVGRTEVAKNNLNPIFSKIFEVDYHFEERQIMKVEIYDSDCSSSRLNDQDFQGRYEFSLGELVSRRKIEANLTG--CKSTTGKKQVIILTSHEVENCKELLTLQLNGTKLDKKDTFGKSDPLIEIYRSNEPIKFIRGDSNLNNCNNFTLIYRSRPIMNTLNPSWPQFTLKLGQLCGGDKDKIIKIVCADWNSDGSQDFIGQCFTSVNDLIANTGKGQTFELINIKKQVKKKGYKNSGTLSINKSLIEMDYSFIDFISGGTELNFTVAIDFTGSNGNQSNPKSLHYIPPCAISGSMNQYETAIVSVGSIIQDYDSDKMFPALGFGARIPPNHEISHCFPITFSPQNPFCSGVDGLLKTYRSAIRLVTLCGPTNFSPSIRHVQQFANSYKDGSKYFVLLIITDGIITDLHETINAIIDCSYLPVSIIIIGVGNEDFSAMDTLDCDKGRLQSGSKVAKRDIVQFVPIRNFMKGPEKDINQFALSKAVLLELPNQVTSWMKLNGKIPL 547
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000003990.1 (SMESG000003990.1) HSP 1 Score: 540.421 bits (1391), Expect = 0.000e+0 Identity = 297/595 (49.92%), Postives = 395/595 (66.39%), Query Frame = 3
Query: 102 IQDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNS-YLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSR--RKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLF---GKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN----EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASN--ENNPISLHFIPQNDFAGPQ-NQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIPLKQKNRNISPQFT---GDAXXXXXXMSDPFALNLSHSMQN 1838
+ + L S+VE+ V+C+NL D D+ SKSDPM VLF + S Y+E RTE + NNLNP F K F +DY+FEE Q K ++YDIDSSS L +H+FLG+FK +LGE+VSR V+ K I++ C+E+SS KEL ++F T + K+ + GK +P L+I+R + P F E K F+L ++T+ + NT P W F V+ RLC G++D+L+++ C +W SG D IG FTS+N LL+N E + L N K I ++SG +TL + V +++F DYIS GT+L+FTVA+DFTASN +NNP+SLH+I N++ PQ NQYETAI SVG II+DYD DKMFPALGFGA+IPP+ E+SHCFP++F +NPFC + GLL Y+ A+R V L+GPTNF+P IRHVQ+FA Y+DGS+YFVLLIITDGII+D + TID+I+DCS LPMSIII+GVGNED+S M+ LDCD G LR+G K+A RDIVQFV LRDFM+ NQ L +AVL ELP QVV WM+ + I+P + I T GD +S P+ +N + QN
Sbjct: 1 MTNHLVSKVELIVSCRNLMDADLLSKSDPMVVLFIKHGTSGYIEYGRTEVVMNNLNPDFNKAFLVDYYFEEIQQLKFQVYDIDSSSPNLSEHDFLGEFKCNLGEIVSRAIHNVKGK---------------IIIRCSEISSCKELFTMRFDATGIPKRGWWIFSGKCNPFLEIHRVNGPHLFTGEEIKNPSRLQFVLAHRTEHLWNTDCPQWKSFQVRNWRLCQGDRDKLLRIDCCNWRHSGSYDLIGSFFTSINDLLQNIGAREHYQLNNFQERRKSIHASQGSDSGRVTLTEFQVDTDHTFVDYISSGTQLHFTVAVDFTASNGPQNNPLSLHYI-NNNYPHPQLNQYETAISSVGRIIEDYDYDKMFPALGFGAKIPPSMELSHCFPLSFQARNPFCYRVDGLLQAYQHAVRQVQLFGPTNFAPCIRHVQRFAEAYQDGSQYFVLLIITDGIITDIDKTIDSIVDCSHLPMSIIIVGVGNEDFSTMNMLDCDNGYLRSGFKVASRDIVQFVPLRDFMNSNESLNNQANLARAVLAELPDQVVHWMRKHKIVPKSAPSPTIGLHSTHPMGDI------ISPPYPINSDVANQN 573
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000003990.1 (SMESG000003990.1) HSP 1 Score: 526.939 bits (1356), Expect = 0.000e+0 Identity = 282/540 (52.22%), Postives = 370/540 (68.52%), Query Frame = 3
Query: 147 KNLKDMDIFSKSDPMAVLFQEFNNS-YLEIDRTETIKNNLNPVFTKNFEIDYHFEERQMFKIEIYDIDSSSNRLVDHEFLGDFKFSLGELVSR--RKVESKLSNRFVDNNTRKPQLIVLTCNELSSSKELIFLQFIGTKLDKKDLF---GKSDPILQIYRSSDPITFLPTETKFNGTRNFLLVYQTKPIMNTLNPSWPEFSVKLSRLCLGEKDRLIKLVCTDWNSSGKLDFIGHCFTSVNHLLENQRKNEAFVLIN----EKKIKKRSYNNSGTLTLNKASVQYEYSFFDYISGGTELNFTVAIDFTASN--ENNPISLHFIPQNDFAGPQ-NQYETAILSVGSIIQDYDSDKMFPALGFGARIPPNKEISHCFPINFSPQNPFCAGITGLLNTYRSAIRAVILYGPTNFSPSIRHVQQFALQYRDGSKYFVLLIITDGIISDFEATIDAIIDCSFLPMSIIIIGVGNEDYSAMDSLDCDKGLLRNGNKIAQRDIVQFVALRDFMDIRTQAINQKALNKAVLFELPGQVVSWMKSNSIIP 1727
+NL D D+ SKSDPM VLF + S Y+E RTE + NNLNP F K F +DY+FEE Q K ++YDIDSSS L +H+FLG+FK +LGE+VSR V+ K I++ C+E+SS KEL ++F T + K+ + GK +P L+I+R + P F E K F+L ++T+ + NT P W F V+ RLC G++D+L+++ C +W SG D IG FTS+N LL+N E + L N K I ++SG +TL + V +++F DYIS GT+L+FTVA+DFTASN +NNP+SLH+I N++ PQ NQYETAI SVG II+DYD DKMFPALGFGA+IPP+ E+SHCFP++F +NPFC + GLL Y+ A+R V L+GPTNF+P IRHVQ+FA Y+DGS+YFVLLIITDGII+D + TID+I+DCS LPMSIII+GVGNED+S M+ LDCD G LR+G K+A RDIVQFV LRDFM+ NQ L +AVL ELP QVV WM+ + I+P
Sbjct: 18 RNLMDADLLSKSDPMVVLFIKHGTSGYIEYGRTEVVMNNLNPDFNKAFLVDYYFEEIQQLKFQVYDIDSSSPNLSEHDFLGEFKCNLGEIVSRAIHNVKGK---------------IIIRCSEISSCKELFTMRFDATGIPKRGWWIFSGKCNPFLEIHRVNGPHLFTGEEIKNPSRLQFVLAHRTEHLWNTDCPQWKSFQVRNWRLCQGDRDKLLRIDCCNWRHSGSYDLIGSFFTSINDLLQNIGAREHYQLNNFQERRKSIHASQGSDSGRVTLTEFQVDTDHTFVDYISSGTQLHFTVAVDFTASNGPQNNPLSLHYI-NNNYPHPQLNQYETAISSVGRIIEDYDYDKMFPALGFGAKIPPSMELSHCFPLSFQARNPFCYRVDGLLQAYQHAVRQVQLFGPTNFAPCIRHVQRFAEAYQDGSQYFVLLIITDGIITDIDKTIDSIVDCSHLPMSIIIVGVGNEDFSTMNMLDCDNGYLRSGFKVASRDIVQFVPLRDFMNSNESLNNQANLARAVLAELPDQVVHWMRKHKIVP 541 The following BLAST results are available for this feature:
BLAST of Copine-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Copine-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Copine-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Copine-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Copine-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Copine-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Copine-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Copine-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033990 ID=SMED30033990|Name=Copine-3|organism=Schmidtea mediterranea sexual|type=transcript|length=1979bpback to top protein sequence of SMED30033990-orf-1 >SMED30033990-orf-1 ID=SMED30033990-orf-1|Name=SMED30033990-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=583bp MNSIQDELKSRVEISVACKNLKDMDIFSKSDPMAVLFQEFNNSYLEIDRTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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