Vacuolar protein sorting-associated protein 11 homolog
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033972 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Human
Match: VPS11 (VPS11 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14583]) HSP 1 Score: 404.445 bits (1038), Expect = 1.069e-123 Identity = 284/897 (31.66%), Postives = 465/897 (51.84%), Query Frame = 3
Query: 105 SRFMGWALFDLFDK----------------TFADESVGKNFRDM--KISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV---KLVKPSVLTGTHLNIKTEQRSTNSTYQIV-IFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIE--NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-------DKQSDS-----KLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAI-QEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
+ ++ W F FDK T A S F + I+ GR L GD+EG ++ + + F AY V + Q K+ + L + G D N ++KIW+ K + N P+ R F ++ PG V C V NLN + +G + V L D + SK + +++ +T +A Q +++V + + S + ++++ C CS L D F+VA + +Y D GPC A +G + + ++ YLI+V + V P + T + S +S QI+ I+D N+FIA D + EWGS+YV +V EKD Q+KL++ F+KN F++AI +AKSQ+ D D LA ++ QYGDHLY + ++D A+Q YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + + FD+ +LR+ + AL LA+ + H WYLKI +ED + Y E+++YI +L + E + YG L+ PE + L+ +C + +SD + N + +F NN + LK FL ++S++ D +Y DTLLEL L EK+P++ EK AE + +L++ KALV CQ+ F G YL E+ + + +I++ + + V+ C + G+++P+LW +AL + + D K ++ A+ + IE+++L+ PLL+++ + N +++D++++ +K + I + +Y++ET + IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H CFE YS S CP C + +++ D+ + Q K D
Sbjct: 2 AAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGN-PLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIV---SGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPK-------SEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTR--DGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLE-HMSEVQP-DSPQGIY-DTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTL-AHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVM-DMIRAQEQKRD 879
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Human
Match: VPS11 (VPS11 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14583]) HSP 1 Score: 404.445 bits (1038), Expect = 1.069e-123 Identity = 284/897 (31.66%), Postives = 465/897 (51.84%), Query Frame = 3
Query: 105 SRFMGWALFDLFDK----------------TFADESVGKNFRDM--KISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV---KLVKPSVLTGTHLNIKTEQRSTNSTYQIV-IFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIE--NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-------DKQSDS-----KLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAI-QEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
+ ++ W F FDK T A S F + I+ GR L GD+EG ++ + + F AY V + Q K+ + L + G D N ++KIW+ K + N P+ R F ++ PG V C V NLN + +G + V L D + SK + +++ +T +A Q +++V + + S + ++++ C CS L D F+VA + +Y D GPC A +G + + ++ YLI+V + V P + T + S +S QI+ I+D N+FIA D + EWGS+YV +V EKD Q+KL++ F+KN F++AI +AKSQ+ D D LA ++ QYGDHLY + ++D A+Q YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + + FD+ +LR+ + AL LA+ + H WYLKI +ED + Y E+++YI +L + E + YG L+ PE + L+ +C + +SD + N + +F NN + LK FL ++S++ D +Y DTLLEL L EK+P++ EK AE + +L++ KALV CQ+ F G YL E+ + + +I++ + + V+ C + G+++P+LW +AL + + D K ++ A+ + IE+++L+ PLL+++ + N +++D++++ +K + I + +Y++ET + IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H CFE YS S CP C + +++ D+ + Q K D
Sbjct: 2 AAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGN-PLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIV---SGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPK-------SEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTR--DGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLE-HMSEVQP-DSPQGIY-DTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTL-AHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVM-DMIRAQEQKRD 879
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Human
Match: VPS11 (VPS11 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14583]) HSP 1 Score: 393.66 bits (1010), Expect = 6.660e-120 Identity = 271/844 (32.11%), Postives = 448/844 (53.08%), Query Frame = 3
Query: 210 GRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV---KLVKPSVLTGTHLNIKTEQRSTNSTYQIV-IFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIE--NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-------DKQSDS-----KLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAI-QEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
GR + +EG ++ + + F AY V + Q K+ + L + G D N ++KIW+ K + N P+ R F ++ PG V C V NLN + +G + V L D + SK + +++ +T +A Q +++V + + S + ++++ C CS L D F+VA + +Y D GPC A +G + + ++ YLI+V + V P + T + S +S QI+ I+D N+FIA D + EWGS+YV +V EKD Q+KL++ F+KN F++AI +AKSQ+ D D LA ++ QYGDHLY + ++D A+Q YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + + FD+ +LR+ + AL LA+ + H WYLKI +ED + Y E+++YI +L + E + YG L+ PE + L+ +C + +SD + N + +F NN + LK FL ++S++ D +Y DTLLEL L EK+P++ EK AE + +L++ KALV CQ+ F G YL E+ + + +I++ + + V+ C + G+++P+LW +AL + + D K ++ A+ + IE+++L+ PLL+++ + N +++D++++ +K + I + +Y++ET + IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H CFE YS S CP C + +++ D+ + Q K D
Sbjct: 45 GRLLDYPAHMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGN-PLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIV---SGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPK-------SEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTR--DGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLE-HMSEVQP-DSPQGIY-DTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTL-AHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVM-DMIRAQEQKRD 869
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Human
Match: VPS11 (VPS11 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14583]) HSP 1 Score: 393.66 bits (1010), Expect = 6.660e-120 Identity = 271/844 (32.11%), Postives = 448/844 (53.08%), Query Frame = 3
Query: 210 GRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV---KLVKPSVLTGTHLNIKTEQRSTNSTYQIV-IFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIE--NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-------DKQSDS-----KLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAI-QEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
GR + +EG ++ + + F AY V + Q K+ + L + G D N ++KIW+ K + N P+ R F ++ PG V C V NLN + +G + V L D + SK + +++ +T +A Q +++V + + S + ++++ C CS L D F+VA + +Y D GPC A +G + + ++ YLI+V + V P + T + S +S QI+ I+D N+FIA D + EWGS+YV +V EKD Q+KL++ F+KN F++AI +AKSQ+ D D LA ++ QYGDHLY + ++D A+Q YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + + FD+ +LR+ + AL LA+ + H WYLKI +ED + Y E+++YI +L + E + YG L+ PE + L+ +C + +SD + N + +F NN + LK FL ++S++ D +Y DTLLEL L EK+P++ EK AE + +L++ KALV CQ+ F G YL E+ + + +I++ + + V+ C + G+++P+LW +AL + + D K ++ A+ + IE+++L+ PLL+++ + N +++D++++ +K + I + +Y++ET + IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H CFE YS S CP C + +++ D+ + Q K D
Sbjct: 45 GRLLDYPAHMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGN-PLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIV---SGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPK-------SEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTR--DGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLE-HMSEVQP-DSPQGIY-DTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTL-AHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVM-DMIRAQEQKRD 869
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Human
Match: VPS11 (VPS11 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14583]) HSP 1 Score: 150.984 bits (380), Expect = 5.609e-38 Identity = 105/338 (31.07%), Postives = 185/338 (54.73%), Query Frame = 3
Query: 1692 NYGNRLISIEPEILVEQLERVC-------DKQSD-----SKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAI-QEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
YG L+ PE + L+ +C + +SD + N + +F NN + LK FL ++S++ D +Y DTLLEL L EK+P++ EK AE + +L++ KALV CQ+ F G YL E+ + + +I++ + + V+ C + G+++P+LW +AL + + D K ++ A+ + IE+++L+ PLL+++ + N +++D++++ +K + I + +Y++ET + IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H CFE YS S CP C + +++ D+ + Q K D
Sbjct: 3 RYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLE-HMSEVQP-DSPQGIY-DTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTL-AHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVM-DMIRAQEQKRD 335
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Celegans
Match: vps-11 (Vacuolar protein sorting-associated protein 11 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q09600]) HSP 1 Score: 201.445 bits (511), Expect = 9.430e-53 Identity = 159/600 (26.50%), Postives = 289/600 (48.17%), Query Frame = 3
Query: 843 CRALDGDNI--CLYVYKHY--LIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQDCTAEHNV-LLLNCYIILKKQKDLKKFI----ENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQL-ERVCDKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEP-NLWIKALEFLIK--VNPDEKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSR-SKNQCPNC 2600
C +DG + CL + + + L +V + L H ++ ++R + + ++D +++ SLP+ LFI GS + SH + EK++ +KL I +K+ F +A+ IAK+ D L ++ +YG++LY + Y+ AIQ Y +TIG +EPS+V+ ++L +S+I L YLE L EH +L+N Y ++K L +F+ + ++ + + VF +L K + EA LA +++ H L ++I KY V YIS++ + E +G L+ + L+ L E++ + K N I +F+ + + FLS YI + +++ + L + E+ ++ + N + AL QL T ++ + E++ ++ +++++ ++ C +E LW+ AL F+ K DE +D ++EIE+ I PL++LE + H L V+D+I+ + K + +I++ N I + + ++ L QI Q KC C L +P+VHFLC H+YH+ CFE Y+ ++CP C
Sbjct: 255 CIDMDGGEVGRCLQLGRGHEKLQLVASGQYLALLTKHHSLIQKERDSEFMTMLSVYDIKGQYVGFSCSLPNLCRLFIA-GSTMLVLSHD-GLLSELIEKNLATKLDILVKKSMFDVAVLIAKNSRDGGDYLKGIHAKYGNYLYGKGDYENAIQQYKETIGMLEPSYVMKRYLDSSKIKELCIYLECLHDAKRDNEHQTKILMNAYAKQGEKKKLMEFVNKITDGTRVSR--MRDVFEILLKWNYLAEASLLATKFQMHEDALNVIIHHMHKYTMGVTYISKMPIESVIEMTGKFGRDLLIHARDDLMHMLWEKIQENTDAKKNNFMRIFDIFMGDMDASRVFLS-YIE--NQTNEHDEFIIPILECQMRLFKVNSDWSQERLEEDIYRFINKKN----EDAALQMAQLFDCTPVIEHILMRCHKSKELMMYHQKKRDLEAIIRLCQSCSKEEKRRLWLDALSFIGKHATARDELIIIDLLKEIEASEQIHPLVVLELLAKNEH-LTISSVRDYIIAWLRKQQIIIEEDRNTIKENNKAMGELDGTVESLKFNAQIMQVTKCSACDTPLQLPTVHFLCKHAYHVHCFESYNMDGSDKCPAC 842
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Fly
Match: Vps11 (gene:FBgn0052350 transcript:FBtr0070046) HSP 1 Score: 68.5514 bits (166), Expect = 2.490e-11 Identity = 50/227 (22.03%), Postives = 101/227 (44.49%), Query Frame = 3
Query: 777 DNVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTN---KVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYR-QYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQDCTAEHNVLLLNCYI 1445
D++ VV +Y + GPC A++G CL HYLIV +K N+T +++ D N+ I + + ++ E Y+ + + + + + +++ +K+ + +A+ + + + + R QYG+HL ++ + A Q +IKTIG ++P VIS+ L + L+ YL +++ ++ + L+ C I
Sbjct: 246 DSMLVVGRADAVYCYTPEGRGPCFAIEGAKECLAWVGHYLIV--------------GVKNSNLKQNAT-TLIVLDTENKIIVFQRQFQELFYVISENNFCYIVTNSGDTDACNMLMLEKNSIDVNIRLLVEKHMYNIALRLLHREGYTSSPETALVRFQYGNHLLQKGDFSRATQEFIKTIGFIKPYAVISKLLYSRYNTYLLNYLTEWKKKNESSSCHTRLIECCI 457
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Zebrafish
Match: vps11 (VPS11 core subunit of CORVET and HOPS complexes [Source:ZFIN;Acc:ZDB-GENE-050731-5]) HSP 1 Score: 423.705 bits (1088), Expect = 2.721e-131 Identity = 287/880 (32.61%), Postives = 470/880 (53.41%), Query Frame = 3
Query: 105 SRFMGWALFDLFDK-TFADESV-GKNFR-DMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFD----NVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIE-NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC---------------DKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAE--VMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEK-YFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
+ F+ W F FDK T D S GKNF+ M IS GR ++ +GD++G ++ + S F AY V + Q K+ + L++ G D N ++K+W+ K + + P+ R F ++ PG +V C +V NLN + +G + V L D + SK ++E IT +A Q I +++V + ++ + + + ++++ C CS L D + F+VA +Y D GPC A DG + + ++ YL+ L+ S + + + + Q S + + I+D N+FIA D + EWGS YV S T V++ EKD Q+KL++ F+KN F +AI +AKSQ+ D D L++++RQYGDHLY + +D AIQ YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ N + FD+ +LR+ A+ LA+R+ H WYLKI +ED + Y E+++YI +L + E + YG L+ PE L+R+C D+ ++K N + VF NN + L+ FL I ++ VY DTLLEL L + E + +K + + +L+++N V+ KALV CQ+ F G YL EK + Y +I++ + + V++ C ++GD E LW +AL + + + K Y + ++ I+ +L+ PLL+++ + N ++KD+++ E+ + I++ +I +Y++ET IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H C E ++ S+ +CP C + +++ D+ + Q K D
Sbjct: 2 AAFLQWRRFVFFDKETVKDPSENGKNFQLPMGISACDSGRGHIVLGDMDGQIWFLTRSLQLSSFQAYKLRVTHLYQLKQHNILVSVGQDEPGINPLVKVWNLDKRDSGS-PLCTRIFPAI-PGNKPTEVSCLSVHENLNFMAIGFTDGSVVLTKGDITRDRHSKTLSLHEGNCPITGLAFRQAGKITHLFVATLEKVQCYTLSVKE---YPRVELDTHGCALRCSALTDPSQDSQFIVAGDDCVYLYQPDERGPCFAFDGHKLLTHWHRGYLL---LLTHSNKSPSKSDYGSRQTSPTEKHILTIYDLDNKFIAYSAVFDDVIDVLAEWGSFYVLTSDRT--VYMLQEKDTQTKLEMLFKKNLFVMAINLAKSQHLDNDGLSEIFRQYGDHLYVKGDHDGAIQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQALHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKSNESEVHFDVEIAIKVLRQAGYHSHAVFLAERHMHHEWYLKIQLEDLKNYQEALRYIGRLPFDQAESNMKRYGKTLMHHVPESSTILLKRLCTDYHPSKDSTDRDSLDRPVENKANPEEFIPVFANNPRELRLFLEHMI-EVDPFSPE-GVY-DTLLELRLQDWAHEQDPGKKKVLQEAALSLLRSDNTVF--DKALVLCQMHNFKEGVLYLYEKGKLYQQIMHYHMQNEEYGKVVEACKRYGDSEVCLWEQALGYFARKEENCKSYISEVLKHIDDNNLMPPLLVVQTL-AHNSTASLSVIKDYLINKLERETQQIEEDERKIRQYREETAHLRSEIQELKTCAKIFQKTKCSMCNSPLELPSVHFLCGHSFHQHCLESFAESEAECPTCTPENRKVM-DMLRAQDQKRD 864
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Xenopus
Match: vps11 (VPS11, CORVET/HOPS core subunit [Source:NCBI gene;Acc:100101673]) HSP 1 Score: 376.326 bits (965), Expect = 1.452e-113 Identity = 267/871 (30.65%), Postives = 446/871 (51.21%), Query Frame = 3
Query: 105 SRFMGWALFDLFDK-TFADESVGKNFRDM--KISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVL-VQQDCTAEHNVLLLNCYIILKKQKDLKKFIE-NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC--------DKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPD-EKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNK 2654
+ ++ W F F+K G + M ++ GR L GD+ ++ + + F AY V + Q K+ + L++ G D N ++K+W+ K + + P+ R F ++ PG V C V NLN + +G A+ V L D + SK + + E +T +A QT +++V + + Q + + LD C CS L D FVVA ++ +Y D GPC A +G + ++ Y+ YLI+V + G + + R T + I+D N+ IA + + + EWGS+YV + EKD Q+KL++ F+KN F +AI +AKSQ+ D D L++++RQYGDHLY + +D AIQ YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + ++FD+ +LR+ AL LA+++ H WYLKI +ED + + E+++YI +L + E + YG L+ P + L +C + N + +F NN LK FL I + S D VY DTLLEL L E +P++ + + + +L++ KALV CQ+ F G YL E+ + + +I++ + V++ C ++G++E LW +AL + + D ++Y + IE+R+L+ PLL+++ + N +++++++ +K + I++ +++Y+++T + IQ+L +IFQ KC +CS++L++PSVHFLCGHS+H CFE Y+ + CP C + +++ D+ Q Q K
Sbjct: 2 AAYLQWRRFVFFEKEQVRAPGEGGSLLTMPSGLTVCDSGRGSLLFGDILRNIWFLPRSLQLTSFQAYKLRVTHLHQLKQHNILVSVGEDEEGINPLVKVWNLEKRDGGS-PLCTRIFPAI-PGNKPTVVSCITVHENLNFMAIGFADGSVVLTKGDITRDRHSKTQILQEGSYPVTGMAFRQTGKTTHLFVVTTENVRSYELT-QKDYPYTELDSH--GCGLRCSALSDPSQDLQFVVAGNECVYLYQPDERGPCFAFEGQKMIVHWYRGYLIIVSKDRLE-FAGRAGDSQAMDRQT-----LTIYDLSNKLIAYSSAFTEVVDVLAEWGSLYVLTR--DGLLHALHEKDTQTKLEMLFKKNLFVMAISLAKSQHLDSDGLSEIFRQYGDHLYNKGDHDGAIQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQALHLQSLANADHTTLLLNCYTKLKDSARLEEFIKASEGEVRFDVEIAIKVLRQAGYHSHALYLAEKHAHHEWYLKIQLEDIKNFQEALQYIGRLPFPQAESNMKRYGKTLMCHVPNETTQLLNNLCTSFPQNGEGSRVSQSANPEEFIPIFANNPSELKTFLEHMIKEHS--DSPQGVY-DTLLELRLQNWAHELDPQLKNQLHDDAISLLKSGRFKNVFDKALVLCQMHNFQNGVLYLYEQGKLFQQIMHYHMQNDQYQKVIEACERYGEQETCLWEQALSYFARKEEDCKEYIAMVLGHIENRNLMPPLLVVQTL-AHNSTATLSVIREYLINKMQKLSQKIEEDERTVHQYREDTARIRREIQELRTSPKIFQKTKCSICSSSLELPSVHFLCGHSFHQHCFESYAENDVDCPTCLPENRKVL-DMIQAQEEK 854
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Xenopus
Match: vps11 (VPS11, CORVET/HOPS core subunit [Source:NCBI gene;Acc:100101673]) HSP 1 Score: 375.555 bits (963), Expect = 3.471e-113 Identity = 267/876 (30.48%), Postives = 448/876 (51.14%), Query Frame = 3
Query: 105 SRFMGWALFDLFDK-TFADESVGKNFRDM--KISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIV---ILAFNEQSNDI--HVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVL-VQQDCTAEHNVLLLNCYIILKKQKDLKKFIE-NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC--------DKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPD-EKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNK 2654
+ ++ W F F+K G + M ++ GR L GD+ ++ + + F AY V + Q K+ + L++ G D N ++K+W+ K + + P+ R F ++ PG V C V NLN + +G A+ V L D + SK + + E +T +A QT +++V + +V N I + +++ C CS L D FVVA ++ +Y D GPC A +G + ++ Y+ YLI+V + G + + R T + I+D N+ IA + + + EWGS+YV + EKD Q+KL++ F+KN F +AI +AKSQ+ D D L++++RQYGDHLY + +D AIQ YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + ++FD+ +LR+ AL LA+++ H WYLKI +ED + + E+++YI +L + E + YG L+ P + L +C + N + +F NN LK FL I + S D VY DTLLEL L E +P++ + + + +L++ KALV CQ+ F G YL E+ + + +I++ + V++ C ++G++E LW +AL + + D ++Y + IE+R+L+ PLL+++ + N +++++++ +K + I++ +++Y+++T + IQ+L +IFQ KC +CS++L++PSVHFLCGHS+H CFE Y+ + CP C + +++ D+ Q Q K
Sbjct: 2 AAYLQWRRFVFFEKEQVRAPGEGGSLLTMPSGLTVCDSGRGSLLFGDILRNIWFLPRSLQLTSFQAYKLRVTHLHQLKQHNILVSVGEDEEGINPLVKVWNLEKRDGGS-PLCTRIFPAI-PGNKPTVVSCITVHENLNFMAIGFADGSVVLTKGDITRDRHSKTQILQEGSYPVTGMAFRQTGKTTHLFVVTTENVVGSCPCPSTHYPNTIKDYPYTELDSHGCGLRCSALSDPSQDLQFVVAGNECVYLYQPDERGPCFAFEGQKMIVHWYRGYLIIVSKDRLE-FAGRAGDSQAMDRQT-----LTIYDLSNKLIAYSSAFTEVVDVLAEWGSLYVLTR--DGLLHALHEKDTQTKLEMLFKKNLFVMAISLAKSQHLDSDGLSEIFRQYGDHLYNKGDHDGAIQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQALHLQSLANADHTTLLLNCYTKLKDSARLEEFIKASEGEVRFDVEIAIKVLRQAGYHSHALYLAEKHAHHEWYLKIQLEDIKNFQEALQYIGRLPFPQAESNMKRYGKTLMCHVPNETTQLLNNLCTSFPQNGEGSRVSQSANPEEFIPIFANNPSELKTFLEHMIKEHS--DSPQGVY-DTLLELRLQNWAHELDPQLKNQLHDDAISLLKSGRFKNVFDKALVLCQMHNFQNGVLYLYEQGKLFQQIMHYHMQNDQYQKVIEACERYGEQETCLWEQALSYFARKEEDCKEYIAMVLGHIENRNLMPPLLVVQTL-AHNSTATLSVIREYLINKMQKLSQKIEEDERTVHQYREDTARIRREIQELRTSPKIFQKTKCSICSSSLELPSVHFLCGHSFHQHCFESYAENDVDCPTCLPENRKVL-DMIQAQEEK 862
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Xenopus
Match: vps11 (VPS11, CORVET/HOPS core subunit [Source:NCBI gene;Acc:100101673]) HSP 1 Score: 375.555 bits (963), Expect = 3.866e-113 Identity = 267/876 (30.48%), Postives = 448/876 (51.14%), Query Frame = 3
Query: 105 SRFMGWALFDLFDK-TFADESVGKNFRDM--KISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIV---ILAFNEQSNDI--HVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVL-VQQDCTAEHNVLLLNCYIILKKQKDLKKFIE-NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC--------DKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPD-EKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNK 2654
+ ++ W F F+K G + M ++ GR L GD+ ++ + + F AY V + Q K+ + L++ G D N ++K+W+ K + + P+ R F ++ PG V C V NLN + +G A+ V L D + SK + + E +T +A QT +++V + +V N I + +++ C CS L D FVVA ++ +Y D GPC A +G + ++ Y+ YLI+V + G + + R T + I+D N+ IA + + + EWGS+YV + EKD Q+KL++ F+KN F +AI +AKSQ+ D D L++++RQYGDHLY + +D AIQ YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + ++FD+ +LR+ AL LA+++ H WYLKI +ED + + E+++YI +L + E + YG L+ P + L +C + N + +F NN LK FL I + S D VY DTLLEL L E +P++ + + + +L++ KALV CQ+ F G YL E+ + + +I++ + V++ C ++G++E LW +AL + + D ++Y + IE+R+L+ PLL+++ + N +++++++ +K + I++ +++Y+++T + IQ+L +IFQ KC +CS++L++PSVHFLCGHS+H CFE Y+ + CP C + +++ D+ Q Q K
Sbjct: 2 AAYLQWRRFVFFEKEQVRAPGEGGSLLTMPSGLTVCDSGRGSLLFGDILRNIWFLPRSLQLTSFQAYKLRVTHLHQLKQHNILVSVGEDEEGINPLVKVWNLEKRDGGS-PLCTRIFPAI-PGNKPTVVSCITVHENLNFMAIGFADGSVVLTKGDITRDRHSKTQILQEGSYPVTGMAFRQTGKTTHLFVVTTENVVGSCPCPSTHYPNTIKDYPYTELDSHGCGLRCSALSDPSQDLQFVVAGNECVYLYQPDERGPCFAFEGQKMIVHWYRGYLIIVSKDRLE-FAGRAGDSQAMDRQT-----LTIYDLSNKLIAYSSAFTEVVDVLAEWGSLYVLTR--DGLLHALHEKDTQTKLEMLFKKNLFVMAISLAKSQHLDSDGLSEIFRQYGDHLYNKGDHDGAIQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQALHLQSLANADHTTLLLNCYTKLKDSARLEEFIKASEGEVRFDVEIAIKVLRQAGYHSHALYLAEKHAHHEWYLKIQLEDIKNFQEALQYIGRLPFPQAESNMKRYGKTLMCHVPNETTQLLNNLCTSFPQNGEGSRVSQSANPEEFIPIFANNPSELKTFLEHMIKEHS--DSPQGVY-DTLLELRLQNWAHELDPQLKNQLHDDAISLLKSGRFKNVFDKALVLCQMHNFQNGVLYLYEQGKLFQQIMHYHMQNDQYQKVIEACERYGEQETCLWEQALSYFARKEEDCKEYIAMVLGHIENRNLMPPLLVVQTL-AHNSTATLSVIREYLINKMQKLSQKIEEDERTVHQYREDTARIRREIQELRTSPKIFQKTKCSICSSSLELPSVHFLCGHSFHQHCFESYAENDVDCPTCLPENRKVL-DMIQAQEEK 862
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Xenopus
Match: vps11 (VPS11, CORVET/HOPS core subunit [Source:NCBI gene;Acc:100101673]) HSP 1 Score: 306.99 bits (785), Expect = 1.270e-88 Identity = 243/867 (28.03%), Postives = 420/867 (48.44%), Query Frame = 3
Query: 105 SRFMGWALFDLFDK-TFADESVGKNFRDM--KISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVL-VQQDCTAEHNVLLLNCYIILKKQKDLKKFIE-NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC----DKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAA--EVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPD-EKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNK 2654
+ ++ W F F+K G + M ++ GR L GD+ ++ + + F AY V + Q K+ + L++ G D N ++K+W+ K + + P+ R F ++ PG V C V NLN + +G A+ V L D + SK + + E +T +A QT +++V + + ++ + +++ C CS L D FVVA ++ +Y D GPC A +G + ++ Y+ YLI+V + G + + R T + I+D N+ IA + + + EWGS+YV + EKD Q+KL+ F F ++ IA+S N D +L + ++N++ EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + ++FD+ +LR+ AL LA+++ H WYLKI +ED + + E+++YI +L + E + YG L+ P + L +C S+ N + +F NN LK FL I + S D VY DTLLEL L E + K+ + + +L++ KALV CQ+ F G YL E+ + + +I++ + V++ C ++G++E LW +AL + + D ++Y + IE+R+L+ PLL+++ + N +++++++ +K + I++ +++Y+++T + IQ+L +IFQ KC +CS++L++PSVHFLCGHS+H CFE Y+ + CP C + +++ D+ Q Q K
Sbjct: 2 AAYLQWRRFVFFEKEQVRAPGEGGSLLTMPSGLTVCDSGRGSLLFGDILRNIWFLPRSLQLTSFQAYKLRVTHLHQLKQHNILVSVGEDEEGINPLVKVWNLEKRDGGS-PLCTRIFPAI-PGNKPTVVSCITVHENLNFMAIGFADGSVVLTKGDITRDRHSKTQILQEGSYPVTGMAFRQTGKTTHLFVVTTENVRSYELTQKD---YPYTELDSHGCGLRCSALSDPSQDLQFVVAGNECVYLYQPDERGPCFAFEGQKMIVHWYRGYLIIVSKDRLE-FAGRAGDSQAMDRQT-----LTIYDLSNKLIAYSSAFTEVVDVLAEWGSLYVLTR--DGLLHALHEKDTQTKLECVFIDKIF-FSLSIAESLNLDPSSL------------------KQLKNFL------EPSYVIRKFLDAQRIHNLTAYLQALHLQSLANADHTTLLLNCYTKLKDSARLEEFIKASEGEVRFDVEIAIKVLRQAGYHSHALYLAEKHAHHEWYLKIQLEDIKNFQEALQYIGRLPFPQAESNMKRYGKTLMCHVPNETTQLLNNLCTSFPQNGEGSRANPEEFIPIFANNPSELKTFLEHMIKEHS--DSPQGVY-DTLLELRLQNWAHELDPQLKNQLHDDAISLLKSGRFKNVFDKALVLCQMHNFQNGVLYLYEQGKLFQQIMHYHMQNDQYQKVIEACERYGEQETCLWEQALSYFARKEEDCKEYIAMVLGHIENRNLMPPLLVVQTL-AHNSTATLSVIREYLINKMQKLSQKIEEDERTVHQYREDTARIRREIQELRTSPKIFQKTKCSICSSSLELPSVHFLCGHSFHQHCFESYAENDVDCPTCLPENRKVL-DMIQAQEEK 825
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Mouse
Match: Vps11 (VPS11, CORVET/HOPS core subunit [Source:MGI Symbol;Acc:MGI:1918982]) HSP 1 Score: 407.142 bits (1045), Expect = 5.670e-125 Identity = 282/897 (31.44%), Postives = 465/897 (51.84%), Query Frame = 3
Query: 105 SRFMGWALFDLFDKTFADESVGKNFR------------------DMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV---KLVKPSVLTGTHLNIKTEQRSTNSTYQIV-IFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIE--NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-----------DKQSDS-KLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAI-QEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
+ ++ W F F+K E +G + I+ GR L GD+EG ++ + + F AY V + Q K+ + L + G D N ++KIW+ K + N P+ R F ++ PG V C V NLN + +G + V L D + SK + +++ +T +A Q +++V + + S + ++++ C CS L D F+VA + +Y D GPC A +G + ++ ++ YL++V + V P + T + S NS QI+ I+D N+FIA D + EWGS+YV +V EKD Q+KL++ F+KN F++AI +AKSQ+ D D LA ++ QYGDHLY + ++D A+Q YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + + FD+ +LR+ + AL LA+ + H WYLKI +ED + Y E+++YI +L + E + YG L+ PE + L+ +C D+++ S + + + +F NN + LK FL ++S++ D +Y DTLLEL L EK+P+ EK AE + +L++ KALV CQ+ F G YL E+ + + +I++ + + V+ C + G++EP+LW +AL + + D K ++ A+ + IE++SL+ PLL+++ + N +++D++++ +K + I + +Y++ET + IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H CFE YS S CP C + +++ D+ + Q K D
Sbjct: 2 AAYLQWRRFVFFEKELVKEPLGNDGAAPGAAPVSGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGN-PLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIV---SGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIVHWFRGYLVIVSRDRKVSPK-------SEFTSRDSQNSDKQILNIYDLCNKFIAYSAGFEDIVDVLAEWGSLYVLTR--DGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKTKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKTLMHHIPEQTTQLLKGLCTDYRPSLEGRGDREALSCRASSEEFIPIFANNPRELKAFLE-HMSEVQP-DSPQGIY-DTLLELRLQNWAHEKDPQAKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVIAVCERHGEQEPSLWEQALSYFARKEEDCKEYVAAVLRHIENKSLMPPLLVVQTL-AHNSTATLSIIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVM-DMIRAQEQKRD 879
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Mouse
Match: Vps11 (VPS11, CORVET/HOPS core subunit [Source:MGI Symbol;Acc:MGI:1918982]) HSP 1 Score: 99.3673 bits (246), Expect = 2.140e-21 Identity = 101/396 (25.51%), Postives = 170/396 (42.93%), Query Frame = 3
Query: 105 SRFMGWALFDLFDKTFADESVGKNFR------------------DMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV---KLVKPSVLTGTHLNIKTEQRSTNSTYQIV-IFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKN-SFQLAIEIAKSQNF 1208
+ ++ W F F+K E +G + I+ GR L GD+EG ++ + + F AY V + Q K+ + L + G D N ++KIW+ K + N P+ R F ++ PG V C V NLN + +G + V L D + SK + +++ +T +A Q +++V + + S + ++++ C CS L D F+VA + +Y D GPC A +G + ++ ++ YL++V + V P + T + S NS QI+ I+D N+FIA D + EWGS+YV +V EKD Q+KL+ + S+ +E+A F
Sbjct: 2 AAYLQWRRFVFFEKELVKEPLGNDGAAPGAAPVSGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGN-PLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIV---SGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIVHWFRGYLVIVSRDRKVSPK-------SEFTSRDSQNSDKQILNIYDLCNKFIAYSAGFEDIVDVLAEWGSLYVLTR--DGRVHALQEKDTQTKLEARPPGSKSWHKHLEVAPGIGF 383
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Mouse
Match: Vps11 (VPS11, CORVET/HOPS core subunit [Source:MGI Symbol;Acc:MGI:1918982]) HSP 1 Score: 94.3597 bits (233), Expect = 6.517e-21 Identity = 70/238 (29.41%), Postives = 116/238 (48.74%), Query Frame = 3
Query: 540 VDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV---KLVKPSVLTGTHLNIK-TEQRSTNSTYQIV-IFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALA 1226
V L D + SK + +++ +T +A Q +++V + + S + ++++ C CS L D F+VA + +Y D GPC A +G + ++ ++ YL++V + V P+ + T + S NS QI+ I+D N+FIA D + EWGS+YV +V EKD Q+KL++ F+KN F++AI +AKSQ+ D D LA
Sbjct: 16 VTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIV---SGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIVHWFRGYLVIVSRDRKVSPNGCFSFPCRSEFTSRDSQNSDKQILNIYDLCNKFIAYSAGFEDIVDVLAEWGSLYVLTR--DGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLA 248
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. UniProt/SwissProt
Match: sp|Q91W86|VPS11_MOUSE (Vacuolar protein sorting-associated protein 11 homolog OS=Mus musculus OX=10090 GN=Vps11 PE=1 SV=3) HSP 1 Score: 407.142 bits (1045), Expect = 3.966e-124 Identity = 282/897 (31.44%), Postives = 465/897 (51.84%), Query Frame = 3
Query: 105 SRFMGWALFDLFDKTFADESVGKNFR------------------DMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV---KLVKPSVLTGTHLNIKTEQRSTNSTYQIV-IFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIE--NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-----------DKQSDS-KLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAI-QEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
+ ++ W F F+K E +G + I+ GR L GD+EG ++ + + F AY V + Q K+ + L + G D N ++KIW+ K + N P+ R F ++ PG V C V NLN + +G + V L D + SK + +++ +T +A Q +++V + + S + ++++ C CS L D F+VA + +Y D GPC A +G + ++ ++ YL++V + V P + T + S NS QI+ I+D N+FIA D + EWGS+YV +V EKD Q+KL++ F+KN F++AI +AKSQ+ D D LA ++ QYGDHLY + ++D A+Q YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + + FD+ +LR+ + AL LA+ + H WYLKI +ED + Y E+++YI +L + E + YG L+ PE + L+ +C D+++ S + + + +F NN + LK FL ++S++ D +Y DTLLEL L EK+P+ EK AE + +L++ KALV CQ+ F G YL E+ + + +I++ + + V+ C + G++EP+LW +AL + + D K ++ A+ + IE++SL+ PLL+++ + N +++D++++ +K + I + +Y++ET + IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H CFE YS S CP C + +++ D+ + Q K D
Sbjct: 2 AAYLQWRRFVFFEKELVKEPLGNDGAAPGAAPVSGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGN-PLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIV---SGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIVHWFRGYLVIVSRDRKVSPK-------SEFTSRDSQNSDKQILNIYDLCNKFIAYSAGFEDIVDVLAEWGSLYVLTR--DGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKTKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKTLMHHIPEQTTQLLKGLCTDYRPSLEGRGDREALSCRASSEEFIPIFANNPRELKAFLE-HMSEVQP-DSPQGIY-DTLLELRLQNWAHEKDPQAKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVIAVCERHGEQEPSLWEQALSYFARKEEDCKEYVAAVLRHIENKSLMPPLLVVQTL-AHNSTATLSIIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVM-DMIRAQEQKRD 879
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. UniProt/SwissProt
Match: sp|Q9H270|VPS11_HUMAN (Vacuolar protein sorting-associated protein 11 homolog OS=Homo sapiens OX=9606 GN=VPS11 PE=1 SV=1) HSP 1 Score: 403.675 bits (1036), Expect = 7.444e-123 Identity = 284/897 (31.66%), Postives = 465/897 (51.84%), Query Frame = 3
Query: 105 SRFMGWALFDLFDK----------------TFADESVGKNFRDM--KISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV---KLVKPSVLTGTHLNIKTEQRSTNSTYQIV-IFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIE--NHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-------DKQSDS-----KLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXX--XXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAI-QEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
+ ++ W F FDK T A S F + I+ GR L GD+EG ++ + + F AY V + Q K+ + L + G D N ++KIW+ K + N P+ R F ++ PG V C V NLN + +G + V L D + SK + +++ +T +A Q +++V + + S + ++++ C CS L D F+VA + +Y D GPC A +G + + ++ YLI+V + V P + T + S +S QI+ I+D N+FIA D + EWGS+YV +V EKD Q+KL++ F+KN F++AI +AKSQ+ D D LA ++ QYGDHLY + ++D A+Q YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI+ + + FD+ +LR+ + AL LA+ + H WYLKI +ED + Y E+++YI +L + E + YG L+ PE + L+ +C + +SD + N + +F NN + LK FL ++S++ D +Y DTLLEL L EK+P++ EK AE + +L++ KALV CQ+ F G YL E+ + + +I++ + + V+ C + G+++P+LW +AL + + D K ++ A+ + IE+++L+ PLL+++ + N +++D++++ +K + I + +Y++ET + IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H CFE YS S CP C + +++ D+ + Q K D
Sbjct: 2 AAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGN-PLCTRIFPAI-PGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIV---SGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPK-------SEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTR--DGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLE-HMSEVQP-DSPQGIY-DTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTL-AHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVM-DMIRAQEQKRD 879
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. UniProt/SwissProt
Match: sp|Q9SJ40|VPS11_ARATH (Vacuolar protein-sorting-associated protein 11 homolog OS=Arabidopsis thaliana OX=3702 GN=VPS11 PE=1 SV=1) HSP 1 Score: 259.225 bits (661), Expect = 7.038e-71 Identity = 231/931 (24.81%), Postives = 417/931 (44.79%), Query Frame = 3
Query: 192 ISCTHFGRNYLWIGDLEGIVYRFDKDFT-TSMFIAYNTCVFQILQYKEKDYLITSGID-----SSTNDVIKIWDTTKWNKNNIPV-------LLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVY---SDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKLI---KFDIVKVFNLLRKVHLFEEALALAKRYEEHNW---------------------------------YLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISI-------------EPEILVEQLER----VCDKQSDSKLNITTILKVFVN----------NRKGLKQFLSRY--ISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAEVMEILQNNNL---VYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDK----EPNLWIKALEFLIKVNPD-EKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFDSALDINTLSLEKLWFNVL 2714
I C GR + IG +G V D+ S F A+++ V + K++++L+T G D + +K++D K + +LR FT+ P + K+ F V + ++L +Y D + ++ K + IT + ++ + + + + Q + +LD G ++ + +V + +Y +D GPC A +G+ + ++ YL+ V + ++ N+ + + +D NR IA + + + EWG+I + + + + TEKD++SKL + F+KN + +AI + +SQ+ D A A++ R+YGDHLY ++ +DEA+ YI TIG +EPSFVI +FL +I NL YLE L ++ + +H LLLNCY LK + L FI I KFD+ + R + E A+ +AK+ +H W Y KILIE + K E++ + +L TE+ + N +S+ P L+ LER V D + +++N T+L+++++ + GL + L + + +S D D+ + E ++ E++++ ++L +Y A++ C++ F G YL EK + Y E++ Y + +G++ C + GD +P+LW L++ ++ D K + + IE ++ P+++L+ + N L ++KD+I R E+ K+I++ + KY++ TK I+DL +IFQ KC C+ LDIP+VHF+C HS+H C ++ +CP C + ++ + N D L + K F+V+
Sbjct: 26 IQCCSSGRGKVVIGSNDGSVSFLDRGVKFDSGFQAHSSSVLFLQHLKQRNFLVTVGEDEQISPQQSGMCLKVFDLDKVQEEGTSSSAPECIGILRIFTNQFP---EAKITSFLVLEEVPPILLIAIGLDNGCIYCVKGDIARERITRFKLQVDGRSAITGLGFRMDGQALLLFAVTPESVNLFSMQAQPPKLQ-TLD-HIGGSVNTVTMSDRSELIVGRPEAVYFYEVDGRGPCWAFEGEKKFMGWFRGYLLCVI---------------DDSKTGNTVFNV--YDLRNRLIAYSIVVDKVSNMLCEWGNIILIKADKS--LLCITEKDMESKLDMLFKKNLYTVAINLVQSQHADAAATANVMRKYGDHLYGKQDFDEAMLQYINTIGYLEPSFVIQKFLDAQRIYNLTNYLEKLHEKGLASKDHTTLLLNCYTKLKDVEKLNTFIRKEDGIGELKFDVETAIRVCRAANYHEHAMYVAKKAGKHEWYLKILLEDLGNYDEALQYVSSLEPSQAGVTIEQYGKILIEHKPK--ETIDILMRLC---TEQGIPN--GVFLSMLPSPVDFITVFVQHPHSLMHFLERYAEIVQDSPAQAEIN-NTLLELYLSRDLNFPSISLSENGLDKDLIDHSVAAAVSKADPEKKTNADSKDAMEKDCTE-----RQQKGLELLKMAWPSDLEQPLYDVDLAVILCEMNSFKDGLLYLYEKMKFYKEVIACYMQNHDHEGLIACCKRLGDSSKGGDPSLWADLLKYFGEIGEDCTKEVKEVLTYIERDDILPPIIVLQTLA-KNPCLTLSVIKDYIARKLEQESKIIEEDRRAVEKYQETTKNMRKEIEDLRTNARIFQLSKCTACTFTLDIPAVHFMCMHSFHQRCL---GDNEKECPECAPEYRSVMEMKRSLEQNSKDQDLFFQQVKGSKDGFSVI 915
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. UniProt/SwissProt
Match: sp|Q54YP4|VPS11_DICDI (Vacuolar protein sorting-associated protein 11 homolog OS=Dictyostelium discoideum OX=44689 GN=vps11 PE=3 SV=1) HSP 1 Score: 257.299 bits (656), Expect = 3.440e-70 Identity = 187/583 (32.08%), Postives = 294/583 (50.43%), Query Frame = 3
Query: 120 WALFDLFD----KTFADESVGKNFRDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQ--ITTVAVNQT--------NDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILF--DNVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVK-------LVKPSVLTGTHLNIKTEQRSTNSTYQ------------IVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC 1757
W F FD K E G + + + I+CT GR L IGD EG + D++F S F AY V I Q KE+++L + G D ++KIW+ K +KN P+ +RS E V CF + +L+ +++GLAN ++ ++ +D + K +++I ++P IT + T + +V T+ ++ ++ D +D E G S L D ++A IY +D GPC G + ++ YL+V+ + P + G +I T S + I+D N++I + + EWGSI+++ + KVF EKD Q+KL+ F+K+S+Q+AI++AKSQ++D A+AD+YR+YGD LY + YD AI Y+ TIG++EPS+VI +FL +I NL Y++ L +++ TA H LLLNCY LK K L FI FD+ + R+ F+ AL LA ++ H+WYLKIL+ED +Y +++ YI L E ++ L YG +L+S PE L ++C
Sbjct: 4 WKRFTFFDIETVKQVEKED-GSSLQKLSITCTTSGRGSLIIGDAEGFINFVDREFGISSFQAYQQSVSLIYQLKERNFLSSVGHDDIGGAAILKIWNLDKTDKNEQPICVRSIKL----EKSVTVTCFTLLEDLSQIIVGLANGEIIIIRAD-IFRDKVIKQKIIKVPNDSPITGLGFFPTKSQQSASAGAVLFVVTTTH----VITYHTAHKDQETIIDDEGGDIG---SFLMSDDGSPIIARSDAIYFYNVDGRGPCFGFTGVKTKVLWFRSYLVVIGYDTNNTNALFPGAVVGGQNSIGGLGSQTGSIGSPSVMVQNTKNNVLNIYDLKNKYIGFTEKFDTVSHICSEWGSIFIFGAD--GKVFQLEEKDTQTKLETLFKKHSYQVAIDLAKSQHYDNSAIADVYREYGDRLYAKGDYDGAITQYLCTIGQLEPSYVIRKFLDAQRIHNLTSYIQALHEKNLATANHTTLLLNCYTKLKDVKKLDHFIMTDNGT-FDVETAIKVCRQGGYFDRALFLASKHSRHDWYLKILLEDLNEYRKALDYIQTLDWEEADKNLKKYGKQLVSEIPEETTGVLMKLC 570 HSP 2 Score: 135.576 bits (340), Expect = 7.258e-31 Identity = 74/224 (33.04%), Postives = 118/224 (52.68%), Query Frame = 3
Query: 1953 KSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPD-EKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEI 2621
K A+ E L N + + AL+ Q+ + G YL EK E + EI+ + + DG++ C ++G K+PNLW++AL F D + ++ + I+ +LI PLL+++ ++ N ++KD+I R + + ID + +I +Y DET+K I +L +IFQ KC+ C LD+PSVHFLC HS+H C R C +I+EI
Sbjct: 692 KRKAKAYEFLTNPKSKFDQDHALILVQVHNWKEGVLYLYEKLELFNEIIEYHMENNDYDGLIKACKRYGVKDPNLWVRALSFFSTNKQDCQDEIIEVLTNIDKENLIPPLLVIQILS-QNKNTTLAVIKDYISRRLSQETQQIDKDYTQIRQYADETEKMRHEINELRTNSKIFQQTKCIACLLALDLPSVHFLCQHSFHQRCLGENERECPSCAGANKRIQEI 914
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. UniProt/SwissProt
Match: sp|Q09600|VPS11_CAEEL (Vacuolar protein sorting-associated protein 11 homolog OS=Caenorhabditis elegans OX=6239 GN=vps-11 PE=3 SV=2) HSP 1 Score: 201.445 bits (511), Expect = 1.199e-51 Identity = 159/600 (26.50%), Postives = 289/600 (48.17%), Query Frame = 3
Query: 843 CRALDGDNI--CLYVYKHY--LIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQDCTAEHNV-LLLNCYIILKKQKDLKKFI----ENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQL-ERVCDKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEP-NLWIKALEFLIK--VNPDEKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSR-SKNQCPNC 2600
C +DG + CL + + + L +V + L H ++ ++R + + ++D +++ SLP+ LFI GS + SH + EK++ +KL I +K+ F +A+ IAK+ D L ++ +YG++LY + Y+ AIQ Y +TIG +EPS+V+ ++L +S+I L YLE L EH +L+N Y ++K L +F+ + ++ + + VF +L K + EA LA +++ H L ++I KY V YIS++ + E +G L+ + L+ L E++ + K N I +F+ + + FLS YI + +++ + L + E+ ++ + N + AL QL T ++ + E++ ++ +++++ ++ C +E LW+ AL F+ K DE +D ++EIE+ I PL++LE + H L V+D+I+ + K + +I++ N I + + ++ L QI Q KC C L +P+VHFLC H+YH+ CFE Y+ ++CP C
Sbjct: 255 CIDMDGGEVGRCLQLGRGHEKLQLVASGQYLALLTKHHSLIQKERDSEFMTMLSVYDIKGQYVGFSCSLPNLCRLFIA-GSTMLVLSHD-GLLSELIEKNLATKLDILVKKSMFDVAVLIAKNSRDGGDYLKGIHAKYGNYLYGKGDYENAIQQYKETIGMLEPSYVMKRYLDSSKIKELCIYLECLHDAKRDNEHQTKILMNAYAKQGEKKKLMEFVNKITDGTRVSR--MRDVFEILLKWNYLAEASLLATKFQMHEDALNVIIHHMHKYTMGVTYISKMPIESVIEMTGKFGRDLLIHARDDLMHMLWEKIQENTDAKKNNFMRIFDIFMGDMDASRVFLS-YIE--NQTNEHDEFIIPILECQMRLFKVNSDWSQERLEEDIYRFINKKN----EDAALQMAQLFDCTPVIEHILMRCHKSKELMMYHQKKRDLEAIIRLCQSCSKEEKRRLWLDALSFIGKHATARDELIIIDLLKEIEASEQIHPLVVLELLAKNEH-LTISSVRDYIIAWLRKQQIIIEEDRNTIKENNKAMGELDGTVESLKFNAQIMQVTKCSACDTPLQLPTVHFLCKHAYHVHCFESYNMDGSDKCPAC 842
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. TrEMBL
Match: A0A4Y2DXN7 (Vacuolar protein sorting-associated protein 11 homolog OS=Araneus ventricosus OX=182803 GN=VPS11 PE=3 SV=1) HSP 1 Score: 471.855 bits (1213), Expect = 2.890e-146 Identity = 302/874 (34.55%), Postives = 477/874 (54.58%), Query Frame = 3
Query: 111 FMGWALFDLFDKTFADES----VGKNFRDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFD----NVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV----KLVKPSVLTG-THLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFI-ENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-----DKQSDSKL--NITTILKVFVNNRKGLKQFLSRYIS-KISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEK-YFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKN-QCPNCGDKIEEIISDINQWQSNK 2654
F+ W F+ F+K +S V + +D+ ++CT GR + +GD+EG +Y +K F F AY V I Q + LIT G D + +IK+W+ K+++ P+ +R + P V F N+N L +G A+ V D ++SK+K +T +A Y++V++ I FN D ++ CP CS+L D + FV+ H +Y D GPC A +G+ I L+ ++ YL+VV K V S +T +NI + ++D N+FIA LP + EWGS+YV K++ EKD QSKL + F+KN + LAI +AKSQ +DED L D++RQYGDHLY + +D AI YIKTIGK+E S+VI +FL +I NL YL+ L ++D T +H LLLNCY LK + L +FI + I FD+ + R+ + AL LA+++ +H+WYLKIL+ED + Y +++KYIS+L E + YG L++ PE + L+R+C ++ S+ L N + +FVNN L +FL I + +S Y+ Y++ L L Y E + I +KS ++M++L+N++ Y ++ALV CQ+ F G +L EK + Y +IL + ++ D +M TC +FG +PNLW++AL F + ++K Y + + E+E +L+SP+L+++ M+ +H L+KD+I+RY +K + I + I +Y++ET+K + +++L +IFQ KC C++ L++PSVHFLCGHSYH CFE YS + +CP C + ++++ I + NK
Sbjct: 3 FLQWRRFNFFEKEVVKDSESNQVQEKLKDINVTCTTSGRGQILLGDVEGNIYFLNKQFQLLSFKAYELNVSHIEQLRLNPILITVGADEPGISLLIKVWNVEKYDQAGKPLCVRI---IRPQGTASPVTVFAAHENMNFLAVGFADSSVLFARGDITRERQSKQKMFKVSNSPLTGLAFRSQGKQIYLFVSTTHEIY--CFNLSVKDKETKTLLDDFGCPPKCSVLSDIKQDHQFVIGCHDAVYFYQHDGRGPCLAFEGEKILLHWFRSYLVVVGKDTKAVHSSAMTSPVEMNI------------VTVYDIQNKFIAYSSPLPAVVDVISEWGSLYVLSQ--DGKLYNLQEKDTQSKLDMLFKKNQYALAISLAKSQQYDEDGLIDIFRQYGDHLYAKGDHDGAIAQYIKTIGKLEASYVIRKFLDAQRIHNLTAYLQALHKKDLATEDHTTLLLNCYTKLKDKSKLDEFIMTKDREIHFDVETAMKVCRQAGYYSHALYLAEQHNQHDWYLKILLEDLRDYDKALKYISKLDFEAAEGNMKTYGKVLMAEVPEQTTQLLKRLCTDYNANQMSEKPLSTNPEEFIHIFVNNTDRLLEFLEHMIKIRPTSSSLVYNTYLE--LCLKAYSKETDLAIKKKSELKIMDMLRNSDASYSINQALVLCQMSDFKPGILHLYEKAKLYQQILFYHIENRDFDAIMRTCERFGSYDPNLWVQALWFFCQQEKNQKPYVITILNEVERNNLLSPILVVDIMS-KSHTATLDLIKDYIIRYLQKENEQIAEDERLIKQYREETEKMRNQMEELRNNPKIFQVSKCSGCTHQLELPSVHFLCGHSYHQQCFESYSAEHDSECPLCLSENQKVLGIIRAQEQNK 854
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. TrEMBL
Match: A0A2P6KML9 (Vacuolar protein sorting-associated protein 11 homolog OS=Nephila clavipes OX=2585209 GN=NCL1_35089 PE=3 SV=1) HSP 1 Score: 469.929 bits (1208), Expect = 1.489e-145 Identity = 302/874 (34.55%), Postives = 484/874 (55.38%), Query Frame = 3
Query: 111 FMGWALFDLFDKTFADES----VGKNFRDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDN----VFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVV----KLVKPSVLTG-THLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFI-ENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-----DKQSDSKL--NITTILKVFVNNRKGLKQFLSRYIS-KISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEK-YFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKN-QCPNCGDKIEEIISDINQWQSNK 2654
F+ W F+ F+K +S V + +D+ ++C+ GR + +GD+EG +Y +K F F AY V I Q + LI+ G D N +IK+W+ K +++ P+ +RS + P ++ V F V N+N L +G A+ V V D ++SK+K +T +A +++ ++ S I +FN D + +++ P CS+L D FV+ H +Y D GPC A G+ I L+ ++ YL+VV K V S +T +NI + ++D N+FIA LP + EWGS+YV K++ EKD QSKL + F+KN + LAI +AKSQ +DED L D++RQYGDHLY + +D AI YIKTIGK+E S+VI +FL +I NL YL+ L ++D T +H LLLNCY LK + L +FI + I FD+ + R+ + AL LA+ +++H+WYLKIL+ED + Y +++KYIS+L E + YG L++ PE + L+R+C ++ S+ L N + +FVNN + L +FL I + +S Y+ Y++ L L Y E +P I +K+ ++M++L+N++ Y ++ALV CQ+ F G +L EK + Y +IL + +++D +M TC +FG +PNLW++AL F + ++K Y + + E+E +L+SP+L+++ M +H L+KD+I+RY +K + I + I +Y++ET+K + +++L +IFQ KC C++ L++PSVHFLCGHSYH CFE YS + +CP C + ++++ I + NK
Sbjct: 3 FLQWRRFNFFEKEVVKDSESNQVQEKLKDINVTCSTSGRGQILLGDVEGNIYFLNKQFQLHSFKAYELNVSHIEQLRLNPILISVGADEPGINPLIKVWNVDKCDQSGKPLCVRS---IRPQGVESPVTVFAVHENMNLLAVGFADSSVLFVRGDITRERQSKQKIFKVSSSPLTGLAFRSQGKQIFLFASTSSEIY--SFNLSIKDKETKILLDKFRFPSTCSVLSDAKQDYQFVIGCHDAVYFYQHDGRGPCLAFQGEKILLHWFRSYLVVVGKDTKAVHSSAMTSPVEMNI------------VTVYDIQNKFIAYSSPLPAVVDVISEWGSLYVLSQ--DGKLYNLLEKDTQSKLDMLFKKNQYALAISLAKSQQYDEDGLIDIFRQYGDHLYAKGDHDGAIAQYIKTIGKLEASYVIRKFLDAQRIHNLTAYLQALHRKDLATEDHTTLLLNCYTKLKDKCKLDEFIMTKDREIHFDVETAMKVCRQAGYYSHALYLAEHHDQHDWYLKILLEDLKDYDKALKYISKLDFEAAEGNMKTYGKVLMTEIPEQTTQLLKRLCTDYNANQMSEKPLSTNPEEFIHIFVNNTERLLEFLEHMIKIRPTSSSLVYNTYLE--LCLKAYSKETDPAIKKKNEIKIMDMLRNSDASYSINQALVLCQMSDFKPGILHLYEKAKLYQQILFYHIENRDLDAIMRTCERFGSYDPNLWVQALWFFCQQEKNQKPYVITILNEVERNNLLSPILVVDIMA-KSHTATLDLIKDYIIRYLQKENEQIAEDERLIKQYREETEKMRNQMEELRNNPKIFQVSKCSGCTHQLELPSVHFLCGHSYHQQCFESYSAEHDSECPLCLTENQKVLGIIRAQEQNK 854
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. TrEMBL
Match: R7T5T9 (Vacuolar protein sorting-associated protein 11 homolog OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_218778 PE=3 SV=1) HSP 1 Score: 455.677 bits (1171), Expect = 5.707e-139 Identity = 325/1084 (29.98%), Postives = 531/1084 (48.99%), Query Frame = 3
Query: 111 FMGWALFDLFDKTFA---DESVG-KNFRDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGID-SSTNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFD----NVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVK---LVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKL-------------------IKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC-DKQSDSK------LNITTILKVFVNNRKGLKQFLSRYISKISSIDQ-NYSVYVDTXXXXXXXXXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFL-DAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFDSALDINTLSLEKLWFNVLKNSKHPIMIDPDQFLSDSLAQ-TLLSSDIEITNPNSLSETNDGLIKIPTPVQSRVNSAGTSISKNIESKLNIIPRISAVDKFPTSSPEKPFLAIKKVSSQIILSETPKEAIKFSVPISKDLLIETESNKSDSYKNKNPFEEYLETNESIGNSS-NPFGDIKSSEETYLDNLNPFG 3233
F+ W F+ FD+ DE + +++ ISC+ FGR L GD G +Y + F S F AY V + Q ++ L++ G D + N +IK+W+ K +++ P R + G+ V +V NLN + +G A+ + L D + SK+K IYE + IT +A ++ ++ T+ + ++ + + +LD Q CP HCS+L D N FV+ + + +Y D GPC A DG + L+ ++ YL++V P V GT + E I +++ N+F+A +P+ +F EWGS+YV + K++ EKD Q+KL+I F+KN + LAI++A+SQ +D+D + +++RQYGDHLY + +D AI+ YIKTIGK+E S+VI +FL +I NL KYL+ L + T +H LLLNCY LK L +FI ++ + FD+ + R F AL LA+++++H+ YLK+ +E+ + YV ++ YI QL E E + YG LI+ PE + L+R+C D QS K N + + +FV+N + L FL I Q Y+ ++ L+ ++ + + E+ +E LQ + Y +ALV CQ+ F AG +L E+ + Y +ILN + + +++TC KFG +P LW++AL + + K+++ + + IE ++L+ PLL+++ + N G+++++I+R ++ I + I +Y+++T+K I++L IFQ KC VCS+ L++PSVHFLC HS+H CFE YS S +CP C + ++ DI + Q D L + L S+ + D F + + TL++ + NP P PV+++ + T S P S KP A Q S P++ ++ K + E ++ + NPFEE L N G +S NPF + + Y NPFG
Sbjct: 3 FLQWRRFNFFDREAVVEPDEGTALQTLKNLDISCSAFGRGQLVFGDHSGSLYFLSRHFELSSFKAYGIRVTHLHQARQHGILVSIGEDETGVNPLIKVWNLDKCDRDGNPTCSRIVRAQCGGQQPSPVTALSVHENLNLMAIGFASGSIVLFKGDVTRERHSKQKVIYEGRQPITGLAFKMSSKNTVLFATTKAEVMSFSILAKEKSRKTALD--QHGCPAHCSVLTDITQDNQFVIGSEEAVYFYQQDGRGPCLAFDGTKLQLHWFRGYLVIVGKDTQSLPRVAAGTGSSPSLEMN------MITVYNIQNKFVAYSAPIPEVINVFCEWGSLYVLSA--DGKLYHLQEKDTQTKLEILFKKNLYDLAIKLAQSQQYDQDGIIEIFRQYGDHLYSKGDHDRAIEQYIKTIGKLEASYVIRKFLDAQRIHNLTKYLQALHKAGLATEDHTTLLLNCYTKLKDVSMLDEFIMVRRILADYYHFVIILLIALQDQEVDFDVETAIRVCRSAGYFSHALRLAEKHQQHDSYLKVQLENIKDYVGALVYIGQLDFKEAEVVVKKYGKILITNAPEQSTKLLKRLCTDYQSAGKTNKIQRANASEFIHIFVDNSEMLIDFLEHMIKVQPGSSQIMYNTLLELYLQRYSHQTDGASKTDEER--RCLEFLQGSPNGYDLDQALVMCQMHSFKAGVLFLYERAKLYQQILNYHIEHDDHQHIIETCKKFGTVDPQLWVQALSYFAGKEQNSKHYITEVLSHIEKQNLLPPLLVVQTL-AHNSTATLGIIREYIIRRLQQETDQISEDERLIQQYEEDTQKMKSHIKNLQTSATIFQVSKCSVCSHPLELPSVHFLCQHSFHQHCFESYSESDAECPVCLSENRKVF-DILRAQEQSRD---------LHDQFQTQLDRSQDGFSVIADYFGRNLFNKLTLITDSPQRPNP------------APAPVRAKRPPSTTEPSPT-----------------PLPSEVKPIRASPLPRHQPSPS-APRKKVEMKPAPQKPQIPEKKTEAAG-----NPFEEDLGPNNPFGETSKNPFDE----HDDYPVEANPFG 1024
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. TrEMBL
Match: T1ISE0 (Vacuolar protein sorting-associated protein 11 homolog OS=Strigamia maritima OX=126957 PE=3 SV=1) HSP 1 Score: 447.973 bits (1151), Expect = 2.498e-136 Identity = 335/1073 (31.22%), Postives = 529/1073 (49.30%), Query Frame = 3
Query: 120 WALFDLFDKTFADESVGKNF---RDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGID-SSTNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNV----FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKL--VKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENH-KLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVCD--KQSDSKLNITTIL-----------------KVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAEV--MEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEK-YFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFDSALDINTLSLEKLWFNVLKNSKHPIMIDPDQFLSDSLAQ-TLLSSDIEITNPNSLSETNDGLIKIPTPVQSRVNSAGTSISKNIESKLNIIPRISAVDKFPTSSPEKPFLAIKKVSSQIILSETPKEAIKFSVPISKDLLIETESNKSDSYKNKNPFEEYLETNESIGNSSNPFGDIKSS-EETYLDNLNPF 3230
W F FDK + G+ F +D+ I+ GR + +GD+EGIVY + F AY V + Q ++ + L+++G D N VIKIW+ K +KN +P+ RS T++ PG + V N+N + LG N V L D + SK K ++E P +T +A TN I +++V++ I +N + D +E C CS + D FVVA +Y D GPC A DG I L+ ++ YL+ V PS G L + + ++D N+FIA LP+ + EWGS+YV K++ EKD QSKL + F+K+ + LAIE+AKSQ +DED + D++RQYGDHLY + +D AI+ YIKTIGK+E S+VI +FL +I NL YL+ L +Q T +H LLLNCY LK L +FI+ + F++ + R+ + AL L+++ +H+WYLKI IED Q Y ++ YIS+L E E + YG L++I P + L+++C + S+ L ++L +FVNN K L FL I Q+ S+ +TL+EL L E +E E + K E+ + +LQ+ + Y + LV CQ+ F G YL EK + + +IL Y + + V++TC FG ++ LWI+AL + K + +K Y ++ +Q IE L+SPL+++ + + L ++KD+I++ +K + I + I +Y+D+T K I+D+ + F+ KC C+ L++PSVHFLC HSYHM CFE Y+ ++N+CP C + +++ I + N+ L +++ + L+ ++ + + F + TL++ + P SLS +IP +R SI +P + +D P +S + +++ S+Q++ P K KNPFE + NPF + E+ Y D+LNPF
Sbjct: 7 WRRFKFFDKEVVKDGNGQIFDKLKDISITACTSGRGLIILGDVEGIVYYITRQLELISFKAYELTVNNLQQLRQNNILVSTGEDVPGNNPVIKIWNFDKCDKNGLPLCTRSVTAL-PGNKETPATALAVHENMNFMALGYDNGSVLLFRGDISRDRGSKHKILHEGPNSVTNLAFRNTNKIIHLFVSTTEEIY--CYNIHTKDKDFKYLLEDKGCLSRCSTMSDATLEYQFVVARTDAVYFYQPDGRGPCFAFDGKKIILHWFRGYLVAVGKDGGAPSGSGGQSLAMNI----------VTVYDIQNKFIAYSAPLPEVIDVVSEWGSLYVLGG--DKKLYHLQEKDTQSKLDMLFKKSLYALAIELAKSQQYDEDGVVDIFRQYGDHLYSKGDHDGAIEQYIKTIGKLEASYVIRKFLDAQRIHNLTAYLQALHKQGLATEDHTTLLLNCYTKLKDTDKLNEFIKTKDGSVDFNVEIAIRVCRQACYYRHALLLSEKEGQHDWYLKIQIEDLQDYQTALSYISKLDFIEAESNMKKYGKMLMTIIPNETTQFLKQLCTDFRPSNKPLVDVSMLDGSKPMKIERAEAKDFIHIFVNNSKHLVSFLEHTIKIPLYPAQHSSLVYNTLIELYLQEYNQETEDNLKIEHEIKILNLLQSPDSGYDLDQVLVLCQMNNFKPGILYLYEKAKLFQQILRYYMDRDDFNNVINTCKHFGSQDSKLWIQALWYFSKTDDRQKNYLIEILQHIERERLLSPLMVVNTL-ASSSLTTLAVIKDYIIKQLQKENQQIAEDEAMIKQYRDDTGKMRKEIEDIKHNPREFKVAKCSACNQQLELPSVHFLCHHSYHMHCFESYAENENECPACMPENRKVLEIIKAQEENR----------ELHEIFHHQLEVAEDGFSVVSEYFGRGIFNRVTLVTEALVHKRPPSLS-------RIPIVEPAR------SIK---------LPPVERLD-LPRNSKIRGPMSLPSSSNQLLTRTYP--------------------------KTKNPFE---------AGAPNPFESAPNPFEDPYDDSLNPF 995
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. TrEMBL
Match: A0A419PS51 (Vacuolar protein sorting-associated protein 11-like protein (Fragment) OS=Clonorchis sinensis OX=79923 GN=VPS11 PE=4 SV=1) HSP 1 Score: 448.743 bits (1153), Expect = 1.640e-135 Identity = 279/876 (31.85%), Postives = 448/876 (51.14%), Query Frame = 3
Query: 129 FDLFDKTFADESVGKNFRDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDSSTNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVA---VNQTNDIFYVYVTSGSRI---------VILAFNEQ--------SNDIHVSLDV--EQGA---CPKHCSILFDNV-FVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYC------SHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVCDKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISS-------IDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAIQEIESRSLISPLLLLEKM--TVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISD 2630
F + D + D G F D++ SCT GR +LWIGD G VYR D+ + F A+ V + Q K+ D LIT G+D + +K+W+T KW P R+ T+ PG+ V C V + ++LG ++ L D ++ KR ++ +T + V + V + SR V+ A EQ D +S V GA C S+ D++ F VA+ +Y D GPC A DG+ + L V+K YL++VK L+ T L + S+ + I D N+FIAGEFS+ +FIEW IY+ C + + TEK +KL++ F K +FQ+AI+IAKSQ+F+++ LA ++ Y DHLYK+K YD AI+ Y+KTIG +E SFVI +FL + L YLE L + +++H +LLLNCY L+ + + F++ + ++ ++LR+ + + AL LA+ + ILIED +++ I+Q E A+ NYG+ L+ P ++ L+++C + S++N+ LKVF+NNR GL QFL RYI+ + +D + + + L + + E+ + + +L+++ L Y + KAL+ C R F G YL EKQ Y +L Y + V++TC KFG + P LWI AL + + E++ +L +P+++L+ + T H G ++D++LR+ E I + K + ET +N ++++ L+ +V+IFQ KC++C +L+ PSVHFLC HSYH CFE Y+ ++ CP C K ++++++
Sbjct: 20 FTVRDASLPDLFTG--FSDIRPSCTTSGRGFLWIGDDTGSVYRLDRSQQMTSFKAHAQSVRLMHQSKQHDLLITVGLDDLGEERLKVWNTAKWLNKPTPYCCRTTTTEPPGQSPSHVSCLFVDEQVQFILLGHVRGQLQLFKGDISRERQCKRYLLHTFNTPVTGLGLQLVGPKQPLAKHSVVADSRTSRTPELQSPVVFATTEQYVMSFVLGRRDEVLSKTVLDRFGASFDCSSIVSLTPDDLQFAVASRDAVYFYQSDGRGPCLATDGNKLALSVFKQYLVLVKGPPGLYLSHTGLLSTADNLPLESSVTLTIHDQQNKFIAGEFSIQGVLSMFIEWDGIYLLCLERNAEGALRHTLIGLTEKSTHAKLEMLFSKKNFQMAIDIAKSQHFEQEELARIFGSYADHLYKQKDYDGAIKEYVKTIGILEASFVIQRFLEGGHVTQLACYLEALNAANLASSDHLILLLNCYARLQDKTRINDFLQKPINPQMNVPAALHVLRQANFPDAALRLAQLSGRFADRIGILIEDMDNCGAALEDIAQFPFDEALRAICNYGHILMDRLPTETLQLLDKLCSQPDASRINVHHFLKVFINNRLGLMQFLERYITTSGTTVKVGGVVDALLELLLYEINRLRETQAGSKDSAHERLSQLALRLLRDDKLPYDEKKALLLCHRRAFFDGCIYLWEKQHLYDPLLKHYMSLGAHQKVLETCQKFGKELPKLWILALRYFASKPDCASELQQVVSEVDRLNLATPMVVLQILSETDAEHSCLVGTIRDYLLRHLEAGASQIAALRQGVQKLRSETMRNREVVRSLNSQVKIFQQQKCVLCHQSLEPPSVHFLCDHSYHKMCFENYALNEQSCPECAPKNKKLLAE 893
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Cavefish
Match: vps11 (VPS11 core subunit of CORVET and HOPS complexes [Source:ZFIN;Acc:ZDB-GENE-050731-5]) HSP 1 Score: 423.705 bits (1088), Expect = 3.571e-131 Identity = 288/885 (32.54%), Postives = 466/885 (52.66%), Query Frame = 3
Query: 93 RFKNSRFMGWALFDLFDK-TFAD--ESVGKNFR-DMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFD----NVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKL-IKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC---------------DKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAE--VMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEK-YFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
R K + F+ W F FDK T D E+V KNF IS GR ++ +GD++G ++ + + F AY V + Q K+ L++ G D N ++K+W+T K + + P+ R F ++ PG +V C +V NLN + +G + V L D + SK ++E +T +A Q + +++V + ++ + + + ++++ C CS L D + F+VA +Y D GPC A DG I + ++ YL+ L+ + + + + S + I+D N+FIA D + EWGS YV K+++ EKD Q+KL++ F+KN F +AI +AKSQ+ D D L++++RQYGDHLY + +D AIQ YI+TIGK+EPS+VI +FL +I NL YL+ L +Q A+H LLLNCY LK L++FI++ + + FD+ +LR+ A+ LA+++ H WYLKI +ED + Y E+++YI +L + E + +YG L+ PE L+R+C D+ K N + +F NN + L+ FL I S Q VY DTLLEL L + E E +K A + + +L+ N V+ KALV CQ+ F G YL EK + Y +I++ + + V++ C +GDKE LW +AL + + D K Y + +Q I+ +L+ PLL+++ + N ++KD+++ ++ + I++ +I +Y++ET IQ+L +IFQ KC +C++ L++PSVHFLCGHS+H CFE Y+ S+ +CP C + + + D+ + Q K D
Sbjct: 17 RRKMAAFLQWRRFVFFDKETVKDPNENV-KNFALPHGISACDSGRGHIVLGDMDGQIWFLTRSLQLTAFQAYKLRVTHLYQLKQHSILVSVGQDEHGINPLVKVWNTDKRDSGS-PLCTRIFPAI-PGNKPTEVSCLSVHENLNFMAIGFTDGSVVLTKGDITRDRHSKTLTLHEGNCPVTGLAFRQAGKVTHLFVATLEKVQCYTLSVKE---YPRVELDTHGCALRCSALTDPSQDSQFIVAGDDCVYLYQPDERGPCFAFDGHKILAHWHRGYLL---LLTRDTKSPNKPDFGSRETSPTEKQVLTIYDLDNKFIAYSAPFDDIIDVLAEWGSFYVLTR--DKKMYMLQEKDTQTKLEMLFKKNLFVMAINLAKSQHLDNDGLSEIFRQYGDHLYIKGDHDGAIQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQALHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKSSESEVHFDVEIAIKVLRQAGYHSHAVFLAEKHSHHEWYLKIQLEDLKNYQEALRYIGRLPFEQAETNMKHYGKTLMHHVPESTTVLLKRLCTDYQPSKDSTDQDSLDRSMVDKANSEEFIPIFANNPRELRAFLEHMIKVEPSSPQG--VY-DTLLELRLQDWAHEQEPEKKKALQEAALSLLRRENTVF--DKALVLCQMHNFKEGVLYLYEKGKLYQQIMHYHMQNEEYSKVVEACKTYGDKEVCLWEQALGYFARKEEDCKAYISEVLQHIDQNNLMPPLLVVQTL-AHNSTATLSVIKDYLINKLQRESQQIEEDERKIRQYREETAHLRSEIQELRTSAKIFQKTKCSMCNSPLELPSVHFLCGHSFHQHCFESYAESEAECPTCTPENRK-VKDMLRAQDQKRD 883
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Sea Lamprey
Match: vps11 (VPS11 core subunit of CORVET and HOPS complexes [Source:ZFIN;Acc:ZDB-GENE-050731-5]) HSP 1 Score: 384.03 bits (985), Expect = 3.869e-117 Identity = 263/869 (30.26%), Postives = 437/869 (50.29%), Query Frame = 3
Query: 111 FMGWALFDLFDKTFADESVGK-----NFRDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGID-SSTNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLD---VEQGACPKHCSILFD----NVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSV--LTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYI-KTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC------------DKQSDS------KLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAE--VMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFL-DAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDL-DKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNC 2600
F+ W F FDK A + G + +S GR + GD+ ++ ++ S F AY V + Q K+ + ++ G D N ++K+W+ K +K IP+ R F ++ P +V C + LN + +G + V L+ D + SK + ++E IT +A Q + +++V + N QS + ++ ++ C CS L D N F+VA +Y + GPC A +G+ + ++ YL++V S+ +G+ L+ R + + ++D N+ IA P + +EWGS++V NK+ EKD Q+KL++ F+KN + LAI +AK+Q+ D D LA+++RQYGDHLY + +D AIQ YI +TIGK+EPS+VI +FL +I NL YL+ L +Q +H LLLNCY LK L++FI+ + + FD+ +LR+ ++ AL LA++ +H WYLKI +ED + +++ YI++L + E L YG L+ P L+ +C D + + K N + ++ NNR+ LK FL Q + DTLLEL L + E + +K E M +L + + KAL+ CQ+ F G +L EK + Y +I+ + + V++ C ++ D+E LW +AL + + + + F+ + +Q I+ +L+ PLL+++ + N ++KD+I+R + + I + + Y++ET+K I++L +IFQ KC VC + L++PSVHFLC H+YH CFE Y+ S +CP C
Sbjct: 4 FLQWRRFAFFDKEAARDPAGGAGAFDGLAALNVSVCACGRGQMLFGDILWNIHFLNRSLQLSSFKAYELRVSHLYQLKQHNLFVSVGEDEQGINPMVKVWNMDKRDKTGIPLCCRIFRAI-PSNKPTEVTCLAIHEGLNYMGIGFTDGSVVLIKGDITRDRHSKTQVVHESTYPITGLAFRQVGKVMHLFVVTTD-------NVQSYVLQAKIERHLLDPHGCALRCSTLSDLSQDNQFIVARDDCVYLYQPEERGPCFAFEGEKRLVCWFRGYLVIVSKDSKSMPRASGSGLD-----RQAMDMHMVTVYDLENKLIAYSAPFPHVVDVLVEWGSLFVLTG--DNKLVALHEKDTQTKLEMLFKKNLYVLAISVAKTQHLDTDGLAEIFRQYGDHLYSKGDHDGAIQQYISRTIGKLEPSYVIRKFLDAQRIHNLTAYLQALHRQSRANKDHTTLLLNCYTKLKDSSKLEEFIKTSE-VAFDVETAIKVLRQAGYYDHALYLAEKDGQHEWYLKIQLEDIKDCHKALVYIAKLPFEQAESNLKKYGKTLVQYAPVETTGLLKVLCTGYRPRADPHGGDGDASAFAAEAEKANPEEFIHIYANNREQLKAFLEHMAEVQPRCSQGVN---DTLLELYLCDWMHETDPQKKKNLENATMALLTSGAFNSNFDKALIMCQMNNFKDGILFLYEKAQLYQQIVRFHMESDDYQRVIEACKRYSDRESCLWEQALGYFARKEENCRPFITEVLQHIDQNNLMPPLLVVQTL-AHNSTATLAVIKDYIIRRLQSECEQIAEDEQYVRGYREETEKIRGHIEELRTSSAKIFQVTKCSVCKHPLELPSVHFLCEHAYHQHCFEGYAESDAECPAC 852
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Yeast
Match: PEP5 (Histone E3 ligase, component of CORVET membrane tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p; involved in ubiquitination and degradation of excess histones [Source:SGD;Acc:S000004844]) HSP 1 Score: 64.6994 bits (156), Expect = 7.272e-11 Identity = 53/235 (22.55%), Postives = 107/235 (45.53%), Query Frame = 3
Query: 1119 TEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIP------NLVKYLEVLVQQDCTAEHNVL--------------------------LLNCYIILKKQKDLKKFIENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYL-KILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEP 1724
T K +++++ I QK + A+++AK + + +++++YGD+L+K+ EA YI+ + VE S +IS+F ++P NL YL L++ + +V + N +++ D+ F ++ FD+ + L+++ + LAK+Y + + + IL+ V+++KYI L + ET L+ Y +L+ P
Sbjct: 348 TPKSLENQINIIIQKELYPFALQLAKQHSLSPLDVQEIHKKYGDYLFKKGLRKEATDQYIQCLDVVETSEIISKF-GVKEVPDPESMRNLADYLWSLIKNSISQRDHVTLLLIVLIKLKDVEGIDTFIQHFDRKGIWNEGVVMDDMDDVTFFYSDNDF--FDLDLILELMKESDFKRLSYRLAKKYSKDSLIIVDILLNLLHNPVKAIKYIKSLPIDETLRCLVTYSKKLLEESP 579 HSP 2 Score: 58.5362 bits (140), Expect = 4.812e-9 Identity = 54/176 (30.68%), Postives = 80/176 (45.45%), Query Frame = 3
Query: 2142 TCHKF----GDKEPNLWIKALEFLI--KVNPDEKYFLDAIQEIESRSLIS----PLLLLEKMTVGNHLLPFGLVKDFILRYYE-------KNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFE------RYSRSKNQCPNC 2600
TC KF G +EP L AL + + K+ E + ++E R +I PLL + K ++ FGL++D I+ + + +NEKLI+ Y E+ + + K I+ Q L ++ N C +C LDIP V F CGH YH C R +CP C
Sbjct: 800 TCLKFLEKYGTEEPKLLQVALSYFVSNKLIFKEMGGNEVLKEKVLRPIIEGERMPLLDIIKALSRTNVAHFGLIQDIIIDHVKTEDTEIKRNEKLIESYDKELKEKNKKLKNTINSDQPLHVPLK---NQTCFMCRLTLDIPVVFFKCGHIYHQHCLNEEEDTLESERKLFKCPKC 972
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Nematostella
Match: EDO40103 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S847]) HSP 1 Score: 140.198 bits (352), Expect = 6.319e-36 Identity = 78/238 (32.77%), Postives = 133/238 (55.88%), Query Frame = 3
Query: 1944 ISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEK-YFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNK 2654
I EK A +++L N Y A+V Q+ F AG +L EK + Y +IL+ + + + V+DTC K G ++P+LW++AL + + + K ++ + I +L+SPLL+L+ + + +VKD+I+R + ++LI I +Y +ET+K I +L ++F KC +CS LD+P+VHFLC HS+H CFE Y+ + N+CP C + ++++ I + K
Sbjct: 104 IHEKKA---LDLLMNVEARYDLDHAMVLAQMHHFKAGILFLYEKAKLYQQILHYHMEQNDYTNVIDTCKKHGAQDPSLWVQALSYFARKESNCKDQIIEVLSHINRGNLMSPLLVLQTLAHKS-TATLAVVKDYIVRRLQLEDELIAKDERLIRQYSEETEKMRQQISELKTSAKVFNGSKCNLCSRPLDLPAVHFLCLHSFHQPCFEGYAENDNECPICTPENKKVLDIIRSQEQAK 337
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Nematostella
Match: EDO40102 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S846]) HSP 1 Score: 128.642 bits (322), Expect = 2.756e-31 Identity = 83/233 (35.62%), Postives = 117/233 (50.21%), Query Frame = 3
Query: 1014 FIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQ------------FLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSE 1673
F A + P + EWG++YV K+F EK Q+KL+I F+KN + LAI GDH D AIQ YIKTIG +EPS+VI + FL +I NL YL+ L + +H LLLNCY LK L +FI + K + FD+ + R+ F+ A+ LA ++E+H+WYLKI +ED Y ++++YI+QL E
Sbjct: 272 FEAFTGTFPGVIEVLSEWGNLYVLTM--DKKIFQLEEKPTQTKLEILFKKNLYALAIS------------------KGDH-------DGAIQEYIKTIGHLEPSYVIRKVSHLDLSYVIRKFLDAQRIHNLTAYLQALHEHGLANTDHTTLLLNCYTKLKDVSKLDEFIMSEKELNFDVETAIKVCRQAGYFKHAVNLANKFEQHDWYLKIQLEDLHDYQKALEYIAQLDFYE 477
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Medaka
Match: vps11 (VPS11 core subunit of CORVET and HOPS complexes [Source:NCBI gene;Acc:100049448]) HSP 1 Score: 406.371 bits (1043), Expect = 6.418e-125 Identity = 280/878 (31.89%), Postives = 463/878 (52.73%), Query Frame = 3
Query: 105 SRFMGWALFDLFDKTFADESV--GKNFRDMK-ISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFD----NVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYL-IVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKL-IKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC------------DKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKS--AAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFL-DAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
+ F+ W F FDK + + GK F K IS + GR L +GD+EG ++ + + F AY V + Q K+ L++ G+D N ++K+W+ K + N P+ R F + G +V C ++ NLN + +G + V L D + SK ++E +T +A Q +++V + ++ + + + ++++ C CS L D + F+VA + IY D GPC A DG + + ++ YL +V+K VK TG + S + + ++D N+FIA F D + EWGS Y+ T +F+ EKD Q+KL++ F+KN F +AI +AKSQ+ D D L++++RQYGDHLY + +D AIQ YI+TIGK+EPS+VI +FL +I NL YL+ L ++ A+H LLLNCY LK L++FI++ + + FD+ +LR+ A+ LA++++ H WY+KI +ED + Y E + YI L + E + YG L+ PE L+ +C D +K N + +F NN + LK FL I S Q VY DTLLEL L + E ++ +K E + +L+++N ++ KALV CQ+ F G YL EK + Y +I++ + + V++ C +GD+E LW +AL + K D K F+ + + I+ ++L+ PLL+++ + N ++K++++ ++ + I+ +I++Y++ET I++L +IFQ KC +C++ L++PSVHFLC HS+H CFE Y+ S+ +CP C + +++ D+ + Q K D
Sbjct: 2 AAFLQWRKFVFFDKEAVSDPLDNGKKFVLPKGISASDSGRGLLVLGDMEGRIWLVTRSLQLTSFQAYKLRVTHLYQLKQHSILVSVGLDEHGINPLVKVWNLDKRDSGN-PLCTRIFPA-NLGTKPTEVSCLSIHENLNFMAIGFTDGSVVLTKGDITRDRHSKTVTLHEGSSPVTGLAFRQVKST-HLFVATLEKVYCFTLSTKE---YPKVELDSHGCALRCSSLADPSQDSQFIVAGDECIYLYQPDGRGPCFAFDGQKLLAHWHRGYLFLVIKDVKSPNKTG----FGGGEISPSEKQLLTVYDLDNKFIAYSFCFDDVIDVVAEWGSFYILTRSGT--MFLLQEKDTQTKLEMLFKKNLFVMAINLAKSQHLDSDGLSEIFRQYGDHLYLKGDHDGAIQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQALHRKSLANADHTTLLLNCYTKLKDSSKLEEFIKSSETEVCFDVEIAIKVLRQAGYHRPAVYLAEKHKHHEWYMKIQLEDLKNYQEGLHYIGCLPFEQAESNMKRYGKTLMHHVPEGATLLLKNICTNYYPTGEAVSVDHCQVNKANSEEFIPIFANNPRELKAFLEHMIKVDSCSPQG--VY-DTLLELRLQDWAHEEDLEKKKILQGEAVSLLKSDNTLF--DKALVLCQMHNFKEGILYLYEKGKLYQQIMHYHMQNEEYGKVVEVCKHYGDQEGCLWEQALGYFAKKEEDCKTFISEVLHHIDQKNLMPPLLVVQTL-AHNSTATLSVIKEYLINKLKRESQQIEADDKKISQYREETSVLRSEIKELKTSAKIFQKTKCNMCNSPLELPSVHFLCSHSFHQHCFESYAESEAECPTCTPENRKVM-DMLRSQDQKRD 860
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Medaka
Match: vps11 (VPS11 core subunit of CORVET and HOPS complexes [Source:NCBI gene;Acc:100049448]) HSP 1 Score: 384.03 bits (985), Expect = 8.121e-117 Identity = 272/875 (31.09%), Postives = 452/875 (51.66%), Query Frame = 3
Query: 105 SRFMGWALFDLFDKTFADESV--GKNFRDMK-ISCTHFGRNYLWIGD-LEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFD----NVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKL-IKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVCDKQSDS---------KLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKS--AAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFL-DAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
+ F+ W F FDK + + GK F K IS + GR L +GD L ++ + + F AY V + Q K+ L++ G+D N ++K+W+ K + N P+ R F + G +V C ++ NLN + +G + V L D + SK ++E +T +A Q +++V + ++ + + + ++++ C CS L D + F+VA + IY D GPC A DG + H+ + +L+ PS + ++D N+FIA F D + EWGS Y+ T +F+ EKD Q+KL++ F+KN F +AI +AKSQ+ D D L++++RQYGDHLY + +D AIQ YI+TIGK+EPS+VI +FL +I NL YL+ L ++ A+H LLLNCY LK L++FI++ + + FD+ +LR+ A+ LA++++ H WY+KI +ED + Y E + YI L + E + YG L+ PE L+ +C + + N + +F NN + LK FL I S Q VY DTLLEL L + E ++ +K E + +L+++N ++ KALV CQ+ F G YL EK + Y +I++ + + V++ C +GD+E LW +AL + K D K F+ + + I+ ++L+ PLL+++ + N ++K++++ ++ + I+ +I++Y++ET I++L +IFQ KC +C++ L++PSVHFLC HS+H CFE Y+ S+ +CP C + +++ D+ + Q K D
Sbjct: 2 AAFLQWRKFVFFDKEAVSDPLDNGKKFVLPKGISASDSGRGLLVLGDILLTEIWLVTRSLQLTSFQAYKLRVTHLYQLKQHSILVSVGLDEHGINPLVKVWNLDKRDSGN-PLCTRIFPA-NLGTKPTEVSCLSIHENLNFMAIGFTDGSVVLTKGDITRDRHSKTVTLHEGSSPVTGLAFRQVKST-HLFVATLEKVYV-------SQEYPKVELDSHGCALRCSSLADPSQDSQFIVAGDECIYLYQPDGRGPCFAFDGQKL----LAHWHQITELISPS-----------------EKQLLTVYDLDNKFIAYSFCFDDVIDVVAEWGSFYILTRSGT--MFLLQEKDTQTKLEMLFKKNLFVMAINLAKSQHLDSDGLSEIFRQYGDHLYLKGDHDGAIQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQALHRKSLANADHTTLLLNCYTKLKDSSKLEEFIKSSETEVCFDVEIAIKVLRQAGYHRPAVYLAEKHKHHEWYMKIQLEDLKNYQEGLHYIGCLPFEQAESNMKRYGKTLMHHVPEGATLLLKNICTNYYPTGEAVSVDHCQANSEEFIPIFANNPRELKAFLEHMIKVDSCSPQG--VY-DTLLELRLQDWAHEEDLEKKKILQGEAVSLLKSDNTLF--DKALVLCQMHNFKEGILYLYEKGKLYQQIMHYHMQNEEYGKVVEVCKHYGDQEGCLWEQALGYFAKKEEDCKTFISEVLHHIDQKNLMPPLLVVQTL-AHNSTATLSVIKEYLINKLKRESQQIEADDKKISQYREETSVLRSEIKELKTSAKIFQKTKCNMCNSPLELPSVHFLCSHSFHQHCFESYAESEAECPTCTPENRKVM-DMLRSQDQKRD 836
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Medaka
Match: vps11 (VPS11 core subunit of CORVET and HOPS complexes [Source:NCBI gene;Acc:100049448]) HSP 1 Score: 381.333 bits (978), Expect = 5.523e-116 Identity = 274/878 (31.21%), Postives = 450/878 (51.25%), Query Frame = 3
Query: 105 SRFMGWALFDLFDKTFADESV--GKNFRDMK-ISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDS-STNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNVFVVANHKGIYDVYLDT----IGPCRALDGDNICLYVYKHYL-IVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQD-CTAEHNVLLLNCYIILKKQKDLKKFIENHKL-IKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVC------------DKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKS--AAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFL-DAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFD 2660
+ F+ W F FDK + + GK F K IS + GR L +GD+EG ++ + + F AY V + Q K+ L++ G+D N ++K+W+ K + N P+ R F + G +V C ++ NLN + +G + V L D + SK ++E +T +A Q +++V + ++ + + PK V LD+ GPC A DG + + ++ YL +V+K VK TG + S + + ++D N+FIA F D + EWGS Y+ T +F+ EKD Q+KL++ F+KN F +AI +AKSQ+ D D L++++RQYGDHLY + +D AIQ YI+TIGK+EPS+VI +FL +I NL YL+ L ++ A+H LLLNCY LK L++FI++ + + FD+ +LR+ A+ LA++++ H WY+KI +ED + Y E + YI L + E + YG L+ PE L+ +C D +K N + +F NN + LK FL I S Q VY DTLLEL L + E ++ +K E + +L+++N ++ KALV CQ+ F G YL EK + Y +I++ + + V++ C +GD+E LW +AL + K D K F+ + + I+ ++L+ PLL+++ + N ++K++++ ++ + I+ +I++Y++ET I++L +IFQ KC +C++ L++PSVHFLC HS+H CFE Y+ S+ +CP C + +++ D+ + Q K D
Sbjct: 2 AAFLQWRKFVFFDKEAVSDPLDNGKKFVLPKGISASDSGRGLLVLGDMEGRIWLVTRSLQLTSFQAYKLRVTHLYQLKQHSILVSVGLDEHGINPLVKVWNLDKRDSGN-PLCTRIFPA-NLGTKPTEVSCLSIHENLNFMAIGFTDGSVVLTKGDITRDRHSKTVTLHEGSSPVTGLAFRQVKST-HLFVATLEKVYCFTLSTKEY-------------PK--------------------VELDSHGYGRGPCFAFDGQKLLAHWHRGYLFLVIKDVKSPNKTG----FGGGEISPSEKQLLTVYDLDNKFIAYSFCFDDVIDVVAEWGSFYILTRSGT--MFLLQEKDTQTKLEMLFKKNLFVMAINLAKSQHLDSDGLSEIFRQYGDHLYLKGDHDGAIQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQALHRKSLANADHTTLLLNCYTKLKDSSKLEEFIKSSETEVCFDVEIAIKVLRQAGYHRPAVYLAEKHKHHEWYMKIQLEDLKNYQEGLHYIGCLPFEQAESNMKRYGKTLMHHVPEGATLLLKNICTNYYPTGEAVSVDHCQVNKANSEEFIPIFANNPRELKAFLEHMIKVDSCSPQG--VY-DTLLELRLQDWAHEEDLEKKKILQGEAVSLLKSDNTLF--DKALVLCQMHNFKEGILYLYEKGKLYQQIMHYHMQNEEYGKVVEVCKHYGDQEGCLWEQALGYFAKKEEDCKTFISEVLHHIDQKNLMPPLLVVQTL-AHNSTATLSVIKEYLINKLKRESQQIEADDKKISQYREETSVLRSEIKELKTSAKIFQKTKCNMCNSPLELPSVHFLCSHSFHQHCFESYAESEAECPTCTPENRKVM-DMLRSQDQKRD 830
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Planmine SMEST
Match: SMESG000029776.1 (SMESG000029776.1) HSP 1 Score: 2053.87 bits (5320), Expect = 0.000e+0 Identity = 1041/1046 (99.52%), Postives = 1043/1046 (99.71%), Query Frame = 3
Query: 114 MGWAL-FDLFDKTFADESVGKNFRDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDSSTNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFXXXXXXXXXXXXXXXRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQTNDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQDCTAEHNVLLLNCYIILKKQKDLKKFIENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVCDKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTXXXXXXXXXXXXXXISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPDEKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFDSALDINTLSLEKLWFNVLKNSKHPIMIDPDQFLSDSLAQTLLSSDIEITNPNSLSETNDGLIKIPTPVQSRVNSAGTSISKNIESKLNIIPRISAVDKFPTSSPEKPFLAIKKVSSQIILSETPKEAIKFSVPISKDLLIETESNKSDSYKNKNPFEEYLETNESIGNSSNPFGDIKSSEETYLDNLNPFGPHYLD 3248
MG+ L FDLFDKTFADESVGKNFRDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDSSTNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFNVSNNLNALVLGLANRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQ NDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQDCTAEHNVLLLNCYIILKKQKDLKKFIENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVCDKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTLLELLLYEVEKEPEISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNP+EKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFDSALDINTLSLEKLWFNVLKNSKHPIMIDPDQFLSDSLAQTLLSSDIEITNPNSLSETNDGLIKIPTPVQSRVNSAGTSISKNIESKLNIIPRISAVDKFPTSSPEKPFLAIKKVSSQIILSETPKEAIKFSVPISKDLLIETESNKSDSYKNKNPFEEYLETNESIGNSSNPFGDIKSSEETYLDNLNPFGPHYLD
Sbjct: 1 MGFYLRFDLFDKTFADESVGKNFRDMKISCTHFGRNYLWIGDLEGIVYRFDKDFTTSMFIAYNTCVFQILQYKEKDYLITSGIDSSTNDVIKIWDTTKWNKNNIPVLLRSFTSVTPGEIDFKVICFNVSNNLNALVLGLANRKVDLVYSDNVTAKKSKRKQIYEMPEQITTVAVNQINDIFYVYVTSGSRIVILAFNEQSNDIHVSLDVEQGACPKHCSILFDNVFVVANHKGIYDVYLDTIGPCRALDGDNICLYVYKHYLIVVKLVKPSVLTGTHLNIKTEQRSTNSTYQIVIFDHVNRFIAGEFSLPDFNFLFIEWGSIYVYCSHPTNKVFIFTEKDVQSKLKIFFQKNSFQLAIEIAKSQNFDEDALADMYRQYGDHLYKEKHYDEAIQNYIKTIGKVEPSFVISQFLSTSQIPNLVKYLEVLVQQDCTAEHNVLLLNCYIILKKQKDLKKFIENHKLIKFDIVKVFNLLRKVHLFEEALALAKRYEEHNWYLKILIEDQQKYVESVKYISQLSLSETEEALLNYGNRLISIEPEILVEQLERVCDKQSDSKLNITTILKVFVNNRKGLKQFLSRYISKISSIDQNYSVYVDTLLELLLYEVEKEPEISEKSAAEVMEILQNNNLVYHKSKALVCCQLRGFTAGYRYLCEKQENYLEILNSYEAEKNVDGVMDTCHKFGDKEPNLWIKALEFLIKVNPNEKYFLDAIQEIESRSLISPLLLLEKMTVGNHLLPFGLVKDFILRYYEKNEKLIDDYHNEINKYKDETKKNIDLIQDLDKEVQIFQNLKCMVCSNNLDIPSVHFLCGHSYHMTCFERYSRSKNQCPNCGDKIEEIISDINQWQSNKFDSALDINTLSLEKLWFNVLKNSKHPIMIDPDQFLSDSLAQTLLSSDIEITNPNSLSETNDGLIKIPTPVQSRVNSAGTSISKNIESKLNIIPRISAVDKFPTSSPEKPFLAIKKVSSQIILSETPKEAIKFSVPISKDLLIETESNKSDSYKNKNPFEEYLETNESIGNSSNPFGDIKSSEETYLDNLNPFGPHYLD 1046 The following BLAST results are available for this feature:
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 3
BLAST of Vacuolar protein sorting-associated protein 11 homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033972 ID=SMED30033972|Name=Vacuolar protein sorting-associated protein 11 homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=3344bpback to top protein sequence of SMED30033972-orf-1 >SMED30033972-orf-1 ID=SMED30033972-orf-1|Name=SMED30033972-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1046bp MGWALFDLFDKTFADESVGKNFRDMKISCTHFGRNYLWIGDLEGIVYRFDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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