SCAN domain-containing protein 3

Overview
NameSCAN domain-containing protein 3
Smed IDSMED30033962
Length (bp)1630
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SCAN domain-containing protein 3 (SMED30033962) t-SNE clustered cells

Violin plots show distribution of expression levels for SCAN domain-containing protein 3 (SMED30033962) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SCAN domain-containing protein 3 (SMED30033962) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SCAN domain-containing protein 3 (SMED30033962) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033962

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymal cellSMED30033962SMESG000019002.1 dd_Smed_v4_11134_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30033962SMESG000019002.1 dd_Smed_v4_11134_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Human
Match: ZMYM6 (zinc finger MYM-type containing 6 [Source:HGNC Symbol;Acc:HGNC:13050])

HSP 1 Score: 63.1586 bits (152), Expect = 1.147e-9
Identity = 58/248 (23.39%), Postives = 108/248 (43.55%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFL--EVDDITXXXXXFDFRDSDW-------------------WLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKD-----EISDLAFQTMEMLLKALDNYFPS----LNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRFLHHTYMNFDFRHWLRSNQRNV 652
            S+  +L  H EVR + +G++L+R+  L+  I  FL  +  D+        F D +W                    L G+        +K+  FK KL +  K+ +E  +D  P   +F++       +I+ + F+ +E L +   + FP      + N +  I++    H+    +  E E+L +L +D+  +  F+   + +FWI+    YPEL  +A+K+   F      +  F     S Q+N+
Sbjct: 1059 SEHVSLPLHAEVRWISRGRMLKRLFELRHEIEIFLSQKHSDLAKY-----FHDEEWVGKLAYLSDIFSLINELNLSLQGTLTTFFNLCNKIDVFKRKLKMWLKRTQENDYDMFPSFSEFSNSSGLNMTDITRIIFEHLEGLSQVFSDCFPPEQDLRSGNLW--IIHPFMNHQNNNLTDFEEEKLTELSSDLGLQALFKSVSVTQFWINAKTSYPELHERAMKFLLPFSTVYLCDAAFSALTESKQKNL 1299
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Human
Match: ZBED5 (zinc finger BED-type containing 5 [Source:HGNC Symbol;Acc:HGNC:30803])

HSP 1 Score: 57.3806 bits (137), Expect = 5.726e-8
Identity = 61/236 (25.85%), Postives = 99/236 (41.95%), Query Frame = 2 
Query:   14 TLLHHTEVRLLFKGKVLERVIHLKTRIISFLEV-----DDITXXXXXF----------DFRDSDWWLNGSAENIMTATSKLLSFKVKLVH-QKKIKEKSFDFLPIVGKF-------TDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF--LHHTYMNFDFRHWLRSNQR 646
             LL +TEVR L +GKVL R+  L+  ++ F++      D +T                   + +  + G    + T   K+ S   KL      ++E++FD  P +  F        DKD I     Q +  L   L  YFP  N N        + T +      ++ E LIDL +D   K NF +  L +FW SL ++YP ++ +A++    F  +H     F +    ++  R
Sbjct:  425 ALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAFRLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEENFDCFPTLSDFLTEINSTVDKD-ICSAIVQHLRGLRATLLKYFPVTNDNNAWVRNPFTVTVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYR 659
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Human
Match: ZBED5 (zinc finger BED-type containing 5 [Source:HGNC Symbol;Acc:HGNC:30803])

HSP 1 Score: 57.3806 bits (137), Expect = 5.726e-8
Identity = 61/236 (25.85%), Postives = 99/236 (41.95%), Query Frame = 2 
Query:   14 TLLHHTEVRLLFKGKVLERVIHLKTRIISFLEV-----DDITXXXXXF----------DFRDSDWWLNGSAENIMTATSKLLSFKVKLVH-QKKIKEKSFDFLPIVGKF-------TDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF--LHHTYMNFDFRHWLRSNQR 646
             LL +TEVR L +GKVL R+  L+  ++ F++      D +T                   + +  + G    + T   K+ S   KL      ++E++FD  P +  F        DKD I     Q +  L   L  YFP  N N        + T +      ++ E LIDL +D   K NF +  L +FW SL ++YP ++ +A++    F  +H     F +    ++  R
Sbjct:  425 ALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAFRLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEENFDCFPTLSDFLTEINSTVDKD-ICSAIVQHLRGLRATLLKYFPVTNDNNAWVRNPFTVTVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYR 659
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Mouse
Match: Zbed5 (zinc finger, BED type containing 5 [Source:MGI Symbol;Acc:MGI:1919220])

HSP 1 Score: 49.2914 bits (116), Expect = 7.670e-12
Identity = 54/220 (24.55%), Postives = 88/220 (40.00%), Query Frame = 2 
Query:   11 KTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDITXXXXXFD-----------------FRDSDWWLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKDEISDLAFQT--------MEMLLKALDNYFPSL-NVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            KTLL HTE R L +GKVL+R+  L+  +  F     I      F                    + +  L G     +  + K+ SF++KL + QKK+ E  F  LP +  F ++ +I      T        ++ML   +  YFP+L  + F   +  +  + +         E    L N    + +F    + +FW+   + YP LS   L+    F
Sbjct:  485 KTLLLHTEGRWLSRGKVLKRIFELRDELKMFFNQKAIRQFEALFSDNSALQKVAYLVDIFTILNELNLSLQGPNSTCLDLSEKIHSFQMKLQLWQKKLDENKFYMLPTLSAFFEEHDIEQHKRITVVISVKEHLDMLASEISWYFPNLPEIPFA--LARSPFSVKAEDVPETAQEDFTRLTNSDAARADFSTMPVTQFWVKCLQSYPVLSEMVLRLLLPF 702

HSP 2 Score: 41.2022 bits (95), Expect = 7.670e-12
Identity = 21/40 (52.50%), Postives = 30/40 (75.00%), Query Frame = 1 
Query:  568 VKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRV 687
            +++LLPF T+YL E  FS+L+ IKSK R RL  VE+++R 
Sbjct:  696 LRLLLPFPTTYLCETGFSSLLVIKSKYRSRL-VVEDDLRC 734
[Close]
BLAST of SCAN domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|O95789|ZMYM6_HUMAN (Zinc finger MYM-type protein 6 OS=Homo sapiens OX=9606 GN=ZMYM6 PE=1 SV=2)

HSP 1 Score: 63.1586 bits (152), Expect = 5.510e-9
Identity = 58/248 (23.39%), Postives = 108/248 (43.55%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFL--EVDDITXXXXXFDFRDSDW-------------------WLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKD-----EISDLAFQTMEMLLKALDNYFPS----LNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRFLHHTYMNFDFRHWLRSNQRNV 652
            S+  +L  H EVR + +G++L+R+  L+  I  FL  +  D+        F D +W                    L G+        +K+  FK KL +  K+ +E  +D  P   +F++       +I+ + F+ +E L +   + FP      + N +  I++    H+    +  E E+L +L +D+  +  F+   + +FWI+    YPEL  +A+K+   F      +  F     S Q+N+
Sbjct: 1059 SEHVSLPLHAEVRWISRGRMLKRLFELRHEIEIFLSQKHSDLAKY-----FHDEEWVGKLAYLSDIFSLINELNLSLQGTLTTFFNLCNKIDVFKRKLKMWLKRTQENDYDMFPSFSEFSNSSGLNMTDITRIIFEHLEGLSQVFSDCFPPEQDLRSGNLW--IIHPFMNHQNNNLTDFEEEKLTELSSDLGLQALFKSVSVTQFWINAKTSYPELHERAMKFLLPFSTVYLCDAAFSALTESKQKNL 1299
[Close]
BLAST of SCAN domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|A4Z944|ZBED5_CANLF (Zinc finger BED domain-containing protein 5 OS=Canis lupus familiaris OX=9615 GN=ZBED5 PE=4 SV=1)

HSP 1 Score: 57.7658 bits (138), Expect = 2.179e-7
Identity = 63/242 (26.03%), Postives = 101/242 (41.74%), Query Frame = 2 
Query:   14 TLLHHTEVRLLFKGKVLERVIHLKTRIISFLEV-----DDITXXXXXF----------DFRDSDWWLNGSAENIMTATSKLLSFKVKLVH-QKKIKEKSFDFLPIVGKF-------TDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNT------SGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF--LHHTYMNFDFRHWLRSNQR 646
             LL +TEVR L +GKVL R+  L+  ++ F++      D +T                   + +  + G    + T   K+ S   KL      ++E++FD  P +  F        DKD I     Q +  L   L  YFP  N N      NT      + T +      ++ E LIDL +D   K NF +  L +FW SL ++YP ++ +A++    F  +H     F +    ++  R
Sbjct:  426 ALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAFRLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEENFDCFPTLSDFLTEINSTVDKD-ICSAIVQHLRGLRSTLLKYFPVTNDN------NTWVRNPFTVTVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYR 660
[Close]
BLAST of SCAN domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q49AG3|ZBED5_HUMAN (Zinc finger BED domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ZBED5 PE=2 SV=2)

HSP 1 Score: 57.3806 bits (137), Expect = 2.750e-7
Identity = 61/236 (25.85%), Postives = 99/236 (41.95%), Query Frame = 2 
Query:   14 TLLHHTEVRLLFKGKVLERVIHLKTRIISFLEV-----DDITXXXXXF----------DFRDSDWWLNGSAENIMTATSKLLSFKVKLVH-QKKIKEKSFDFLPIVGKF-------TDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF--LHHTYMNFDFRHWLRSNQR 646
             LL +TEVR L +GKVL R+  L+  ++ F++      D +T                   + +  + G    + T   K+ S   KL      ++E++FD  P +  F        DKD I     Q +  L   L  YFP  N N        + T +      ++ E LIDL +D   K NF +  L +FW SL ++YP ++ +A++    F  +H     F +    ++  R
Sbjct:  425 ALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAFRLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEENFDCFPTLSDFLTEINSTVDKD-ICSAIVQHLRGLRATLLKYFPVTNDNNAWVRNPFTVTVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYR 659
[Close]
BLAST of SCAN domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|A4Z943|ZBED5_BOVIN (Zinc finger BED domain-containing protein 5 OS=Bos taurus OX=9913 GN=ZBED5 PE=4 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 2.448e-6
Identity = 59/237 (24.89%), Postives = 102/237 (43.04%), Query Frame = 2 
Query:   14 TLLHHTEVRLLFKGKVLERVIHLKTRIISFLEV-----DDITXXXXXF----------DFRDSDWWLNGSAENIMTATSKLLSFKVKLVH-QKKIKEKSFDFLPIVGKF-------TDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNT-SGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF--LHHTYMNFDFRHWLRSNQR 646
             LL +TEVR L +GKVL R+  L+  ++ F++      D +T                   + +  + G    + T   K+ S   KL      ++E++FD  P +  F        DK+ I     Q +  L   L  YFP  N + +  + N  + T +      ++ E LIDL +D   K +F +  L +FW SL ++YP ++ +A++    F  +H     F +    ++  R
Sbjct:  426 ALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAFRLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEENFDCFPTLSDFLTEINSTVDKN-ICSAIVQHLRGLRSTLLKYFPVTN-DIHAWVRNPFTVTVKPASLVARDYESLIDLTSDSQVKQSFSELSLNDFWSSLIQEYPSVARRAVRVLLPFATMHLCETGFSYYAATKTKYR 660
[Close]
BLAST of SCAN domain-containing protein 3 vs. TrEMBL
Match: A0A4U5TVN9 (Zinc finger BED domain-containing protein 5 OS=Collichthys lucidus OX=240159 GN=D9C73_027839 PE=4 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.644e-19
Identity = 61/213 (28.64%), Postives = 100/213 (46.95%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDITXXXXXF------------DFRDSDWWLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKDEISDLAFQTMEMLLKALD----NYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            SD   +L H+E RLL +GKVL RV  L+  I +FLE +  T     F               + +  + GS  ++     K+ SF  KL + ++++ E + D    +  F + +++ +     M+  + AL      YFP  +   Y  I +        +FST E EQ ID+ +D + ++ F+ K L  FWI ++KD+P L  +AL     F
Sbjct:  334 SDHTAVLFHSESRLLSRGKVLSRVFELRDEIRNFLEEEKNTFNNNKFLMKLAYLSDMFQKLNELNLQMQGSDTHLPHLADKITSFTRKLEMWEQRVTEGNIDSFENLKSFIEVNKLQNTVIPCMKAHISALQKHFQRYFPVQDPTQYDWIRDPFSATPPAEFSTTENEQFIDVTSDSIMRLEFKSKTLAAFWIGVEKDFPLLGKRALATLLPF 546

HSP 2 Score: 43.5134 bits (101), Expect = 1.644e-19
Identity = 22/48 (45.83%), Postives = 35/48 (72.92%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRVFINILK 705
            +++  LLPF+TSYL E+ FSA+  IK+K R +L  +E E+RV ++ L+
Sbjct:  538 RALATLLPFATSYLCEIGFSAVASIKTKYRSKLD-IENELRVAVSQLQ 584
[Close]
BLAST of SCAN domain-containing protein 3 vs. TrEMBL
Match: A0A4U5TUJ9 (Zinc finger BED domain-containing protein 5 OS=Collichthys lucidus OX=240159 GN=D9C73_027838 PE=4 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.655e-19
Identity = 61/213 (28.64%), Postives = 100/213 (46.95%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDITXXXXXF------------DFRDSDWWLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKDEISDLAFQTMEMLLKALD----NYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            SD   +L H+E RLL +GKVL RV  L+  I +FLE +  T     F               + +  + GS  ++     K+ SF  KL + ++++ E + D    +  F + +++ +     M+  + AL      YFP  +   Y  I +        +FST E EQ ID+ +D + ++ F+ K L  FWI ++KD+P L  +AL     F
Sbjct:  389 SDHTAVLFHSESRLLSRGKVLSRVFELRDEIRNFLEEEKNTFNNNKFLMKLAYLSDMFQKLNELNLQMQGSDTHLPHLADKITSFTRKLEMWEQRVTEGNIDSFENLKSFIEVNKLQNTVIPCMKAHISALQKHFQRYFPVQDPTQYDWIRDPFSATPPAEFSTTENEQFIDVTSDSIMRLEFKSKTLAAFWIGVEKDFPLLGKRALATLLPF 601

HSP 2 Score: 43.5134 bits (101), Expect = 1.655e-19
Identity = 22/48 (45.83%), Postives = 35/48 (72.92%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRVFINILK 705
            +++  LLPF+TSYL E+ FSA+  IK+K R +L  +E E+RV ++ L+
Sbjct:  593 RALATLLPFATSYLCEIGFSAVASIKTKYRSKLD-IENELRVAVSQLQ 639
[Close]
BLAST of SCAN domain-containing protein 3 vs. TrEMBL
Match: A0A4U5TUW7 (Zinc finger BED domain-containing protein 5 OS=Collichthys lucidus OX=240159 GN=D9C73_027834 PE=4 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.712e-19
Identity = 61/213 (28.64%), Postives = 100/213 (46.95%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDITXXXXXF------------DFRDSDWWLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKDEISDLAFQTMEMLLKALD----NYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            SD   +L H+E RLL +GKVL RV  L+  I +FLE +  T     F               + +  + GS  ++     K+ SF  KL + ++++ E + D    +  F + +++ +     M+  + AL      YFP  +   Y  I +        +FST E EQ ID+ +D + ++ F+ K L  FWI ++KD+P L  +AL     F
Sbjct:  341 SDHTAVLFHSESRLLSRGKVLSRVFELRDEIRNFLEEEKNTFNNNKFLMKLAYLSDMFQKLNELNLQMQGSDTHLPHLADKITSFTRKLEMWEQRVTEGNIDSFENLKSFIEVNKLQNTVIPCMKAHISALQKHFQRYFPVQDPTQYDWIRDPFSATPPAEFSTTENEQFIDVTSDSIMRLEFKSKTLAAFWIGVEKDFPLLGKRALATLLPF 553

HSP 2 Score: 43.5134 bits (101), Expect = 1.712e-19
Identity = 22/48 (45.83%), Postives = 35/48 (72.92%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRVFINILK 705
            +++  LLPF+TSYL E+ FSA+  IK+K R +L  +E E+RV ++ L+
Sbjct:  545 RALATLLPFATSYLCEIGFSAVASIKTKYRSKLD-IENELRVAVSQLQ 591
[Close]
BLAST of SCAN domain-containing protein 3 vs. TrEMBL
Match: A0A0L8FUQ5 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22007300mg PE=4 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 3.034e-19
Identity = 74/216 (34.26%), Postives = 105/216 (48.61%), Query Frame = 2 
Query:   11 KTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDITXXXXXFDF-RDSDWWL-------------------NGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFS-TKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRFL 592
            +  L HTE+R L KGKVL R   L+T +I F + ++       F+F  D + WL                    G+ ENI+T T KL SF  KL +  +K K    D  P V  F ++ EI     +T+E L  +   YFPSL+   Y+ ++N    ++      T   E LID++ND V+K +F    L EFWISL   YP L+  A+   F F+
Sbjct:    6 ECFLLHTELRWLSKGKVLSRFTSLRTEMICFFDAEN-----SGFEFLNDDNLWLEVVFLNDLFEKLDVLNLCLQGANENIITITGKLKSFIDKLELWIRKFKNSQPDCFPSVKAFQNRFEILSEVQKTVENLSVSFSKYFPSLDYQMYEWVINPFARYDSTLLPLTLTDENLIDMENDPVHKASFSVLELSEFWISLWSQYPRLTTTAVTSLFPFV 216
[Close]
BLAST of SCAN domain-containing protein 3 vs. TrEMBL
Match: A0A3Q4HQ00 (Uncharacterized protein OS=Neolamprologus brichardi OX=32507 PE=4 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 3.710e-17
Identity = 61/217 (28.11%), Postives = 98/217 (45.16%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFL--EVDDITXXXXXFDF--------------RDSDWWLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKDEISDLAFQTMEMLLKALD----NYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            SD   +L+H+E R L +GKVL RV  L+  I  FL  E  D+T      +F               + +  +  +  ++   T K+ SF  KL + ++++K+ + D    +  F + +++ +     M+  + AL      YF   +   Y  I +         FST E EQ IDL +D   ++ F  + L  FWI +DKDYP L  +AL     F
Sbjct:   73 SDHTAVLYHSESRWLSRGKVLSRVFELRHEIRIFLKEEGSDLTNKFNCNNFLMKLAYLSDMFLKLNELNLQMQSTNTHLPHLTDKVTSFVRKLEMWKQRVKDGNVDSFENLKSFIEDNKLQNTVIPCMKEHMSALQKHFQRYFLVQDSKEYDWIRDPFSATPPADFSTSEEEQFIDLTSDSTKRLQFNSQTLAAFWIGVDKDYPLLGKRALAILLPF 289

HSP 2 Score: 44.669 bits (104), Expect = 3.710e-17
Identity = 23/48 (47.92%), Postives = 36/48 (75.00%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRVFINILK 705
            +++ ILLPF+TSYL E+ FSA+  IK+K R +L  +E E+RV ++ L+
Sbjct:  281 RALAILLPFATSYLCEVGFSAVASIKTKYRSKLD-IENELRVAVSKLQ 327
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Cavefish
Match: ENSAMXT00000051422.1 (pep primary_assembly:Astyanax_mexicanus-2.0:15:35461191:35465166:-1 gene:ENSAMXG00000032672.1 transcript:ENSAMXT00000051422.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 5.481e-9
Identity = 69/231 (29.87%), Postives = 97/231 (41.99%), Query Frame = 2 
Query:   17 LLHHTEVRLLFKGKVLERVIHLKTRIISFL-----EVDDITXXXXXFDFRDSDWW------------LNG-------------SAENIMTATSKLLSFKVKLVHQKKIKEKSFDFLPIVGKFTDKD------EISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHEC----LKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            LL HTEVR L +GKVL R+  L+  +  FL     E+ D         F D +W             LNG               +N + AT K L    K V Q   +  SFD L     F  K+       +S    + ++ L   L +YFP+L+V+F    +       C       S  E ++LIDL  D   K+ F QK L  FW+    +YP+LS KA+++   F
Sbjct:  402 LLLHTEVRWLSRGKVLARLFELRDEVRIFLLDSNFELSD--------RFTDFEWLAKLSYLSDIFTHLNGLNISLQGKSVTAFHVQNKIEATIKKLDMWTKRVEQSNYE--SFDNL---SDFLTKENASLPNAVSRPIVEHLQSLKMQLRDYFPALDVHFSW--IENPFVDICQGAIASLSASEEDRLIDLSCDSALKLIFSQKSLVNFWLHARSEYPDLSDKAVRFLMPF 617
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Cavefish
Match: ENSAMXT00000044261.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000070.1:2279767:2281653:1 gene:ENSAMXG00000037161.1 transcript:ENSAMXT00000044261.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.3806 bits (137), Expect = 2.697e-8
Identity = 72/232 (31.03%), Postives = 97/232 (41.81%), Query Frame = 2 
Query:   17 LLHHTEVRLLFKGKVLERVIHLKTRIISFL-----EVDDITXXXXXFDFRDSDWW------------LNG-------------SAENIMTATSKLLSFKVKLVHQKKIKEKSFDFLPIVGKFTDKD------EISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILN-----TSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            LL HTEVR L  GKVL R+  L+  +  FL     E+ D         F D +W             LNG               +N + AT K L    K V Q   +  SFD L     F  K+       +S    + ++ L   L +YFP+L+V+F   I N       G    L  S  E ++LIDL  D   K  F QK L  FW+    +YP+LS KA+++   F
Sbjct:  359 LLLHTEVRWLSHGKVLARLFELRDEVRIFLLDSNFELSD--------RFTDFEWLAKLSYLSDIFTHLNGLNLSLQGKSVTAFHVQNKIEATIKKLDMWTKRVEQSNYE--SFDNL---SDFLTKENASLPNAVSRPIVEHLQSLKMQLRDYFPALDVHF-SWIENPFVDICQGAFASL--SASEEDRLIDLSCDSALKFIFSQKSLVNFWLHARSEYPDLSDKAVRFLMPF 574
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Medaka
Match: ENSORLT00000033301.1 (pep primary_assembly:ASM223467v1:24:1653567:1654763:-1 gene:ENSORLG00000025431.1 transcript:ENSORLT00000033301.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.5438 bits (153), Expect = 2.457e-17
Identity = 54/213 (25.35%), Postives = 96/213 (45.07%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDITXXXXXFD-----------------FRDSDWWLNGSAENIMTATSKLLSFKVKLVH-QKKIKEKSFDFLPIVGKF---TDKDEISDLAF--QTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKAL 571
            ++ + +L H+E R L +GKVL RV  L+ +I  FLE +        F                    + +  L G  +++   T K+ SF  KL    +++ E + D    + +F   TD D  S +    + +  L+     YFP  N + Y  + +         FS+ E +Q ID+ +D   ++ F  + L EFW+++++ YP L  +A+
Sbjct:  125 AEHQAVLFHSEARWLSRGKVLSRVFELREQIRMFLEQEHKHEVAEKFSDENFLAKLAYLSDIFGKLNELNLQLQGKDKHLPQVTDKISSFTRKLAMWGRRLDEGNTDSFENLHEFVATTDYDATSVIPHIKEHISSLIGFFKKYFPE-NSSQYDWVRDPFNAPAPTSFSSAEEDQFIDMTSDSTLRLRFTSQTLSEFWLNVERQYPLLGQRAM 336

HSP 2 Score: 45.0542 bits (105), Expect = 2.457e-17
Identity = 22/48 (45.83%), Postives = 35/48 (72.92%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRVFINILK 705
            +++ ILLPF+TSYL E  FSA+  +K+K R +L  +E+E+RV ++  K
Sbjct:  334 RAMGILLPFATSYLCETGFSAVAALKTKYRSQLN-IEQELRVAVSCFK 380
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Medaka
Match: ENSORLT00000040389.1 (pep primary_assembly:ASM223467v1:19:265767:268275:-1 gene:ENSORLG00000025045.1 transcript:ENSORLT00000040389.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.7734 bits (151), Expect = 3.573e-17
Identity = 54/213 (25.35%), Postives = 96/213 (45.07%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDITXXXXXFD-----------------FRDSDWWLNGSAENIMTATSKLLSFKVKLVH-QKKIKEKSFDFLPIVGKF---TDKDEISDLAF--QTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKAL 571
            ++ + +L H+E R L +GKVL RV  L+ +I  FLE +        F                    + +  L G  +++   T K+ SF  KL    +++ E + D    + +F   TD D  S +    + +  L+     YFP  N + Y  + +         FS+ E +Q ID+ +D   ++ F  + L EFW+++++ YP L  +A+
Sbjct:  341 AEHQAVLFHSEARWLSRGKVLSRVFELREQIRMFLEQEHKHEVAEKFSDENFLAKLAYLSDIFGKLNELNLQLQGKDKHLPQVTDKISSFTRKLAMWGRRLDEGNTDSFENLHEFVATTDYDATSVIPHIKEHISSLIGFFKKYFPE-NSSQYDWVRDPFNAPAPTSFSSAEEDQFIDMTSDSTLRLRFTSQTLSEFWLNVERQYPLLGQRAM 552

HSP 2 Score: 45.0542 bits (105), Expect = 3.573e-17
Identity = 22/48 (45.83%), Postives = 35/48 (72.92%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRVFINILK 705
            +++ ILLPF+TSYL E  FSA+  +K+K R +L  +E+E+RV ++  K
Sbjct:  550 RAMGILLPFATSYLCETGFSAVAALKTKYRSQLN-IEQELRVAVSCFK 596
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Medaka
Match: ENSORLT00000035512.1 (pep primary_assembly:ASM223467v1:11:22712371:22714941:1 gene:ENSORLG00000026495.1 transcript:ENSORLT00000035512.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.7734 bits (151), Expect = 3.632e-17
Identity = 54/213 (25.35%), Postives = 96/213 (45.07%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDITXXXXXFD-----------------FRDSDWWLNGSAENIMTATSKLLSFKVKLVH-QKKIKEKSFDFLPIVGKF---TDKDEISDLAF--QTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKAL 571
            ++ + +L H+E R L +GKVL RV  L+ +I  FLE +        F                    + +  L G  +++   T K+ SF  KL    +++ E + D    + +F   TD D  S +    + +  L+     YFP  N + Y  + +         FS+ E +Q ID+ +D   ++ F  + L EFW+++++ YP L  +A+
Sbjct:  341 AEHQAVLFHSEARWLSRGKVLSRVFELREQIRMFLEQEHKHEVAEKFSDENFLAKLAYLSDIFGKLNELNLQLQGKDKHLPQVTDKISSFTRKLAMWGRRLDEGNTDSFENLHEFVATTDYDATSVIPHIKEHISSLIGFFKKYFPE-NSSQYDWVRDPFNAPAPTSFSSAEEDQFIDMTSDSTLRLRFTSQTLSEFWLNVERQYPLLGQRAM 552

HSP 2 Score: 45.0542 bits (105), Expect = 3.632e-17
Identity = 22/48 (45.83%), Postives = 35/48 (72.92%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRVFINILK 705
            +++ ILLPF+TSYL E  FSA+  +K+K R +L  +E+E+RV ++  K
Sbjct:  550 RAMGILLPFATSYLCETGFSAVAALKTKYRSQLN-IEQELRVAVSCFK 596
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Medaka
Match: ENSORLT00000030244.1 (pep primary_assembly:ASM223467v1:13:28104458:28106771:-1 gene:ENSORLG00000022768.1 transcript:ENSORLT00000030244.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.077 bits (144), Expect = 9.609e-15
Identity = 53/219 (24.20%), Postives = 93/219 (42.47%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLE---------------VDDITXXXXXFDFRDS-DWWLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKD---EISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILN---TSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            +D   LL+H+EVR L +G VL R+  L+  + SFL                +  +      F   +  +  L G   NI     K+ +F+ KL +  K+  E+  D  P++    +     +IS    Q +  L +    YFP      +  +++      T   +   +    QL+++  D   K  + +  LG FWI + K+YP L+++A+K    F
Sbjct:  195 ADHVKLLYHSEVRWLSRGLVLTRIFELRKEVFSFLTDKKSPLAHHYTNATFIAKLAYLSDIFSLLNQLNISLQGRNSNIFFVADKVQAFQRKLSLWSKRAHEERLDMFPLLSDILESSPQVKISHSVSQHLSQLAEKFAEYFPEDPREGHMWVVDPFSVDPTENDVALPSHLESQLLEVSTDSTLKGQWGKLDLGSFWIVVSKEYPLLALRAVKVLLPF 413

HSP 2 Score: 39.6614 bits (91), Expect = 9.609e-15
Identity = 20/43 (46.51%), Postives = 31/43 (72.09%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQ-TVEEEMRV 687
            ++VK+LLPF+T+YL E  FS +   K+K R RL+ ++E  +RV
Sbjct:  405 RAVKVLLPFTTTYLCESGFSTVATTKTKARSRLRASLEATLRV 447
[Close]
BLAST of SCAN domain-containing protein 3 vs. Ensembl Medaka
Match: ENSORLT00000032459.1 (pep primary_assembly:ASM223467v1:8:14240678:14247355:1 gene:ENSORLG00000024991.1 transcript:ENSORLT00000032459.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.151 bits (139), Expect = 1.390e-13
Identity = 54/219 (24.66%), Postives = 91/219 (41.55%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLE---------------VDDITXXXXXFDFRDS-DWWLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKD---EISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILN---TSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            +D   LL+H+EVR L +G VL R+  L+  I SFL                +  +      F   +  +  L G   NI     K+ +F+ KL +  K+  E+  D  P++    +     +IS    Q +  L      YFP      +  +++      T   +   +    QL+++  D   K  + +  LG FWI + K+YP L+++A K    F
Sbjct:  324 ADHVQLLYHSEVRWLSRGLVLTRIFELRNEIFSFLTDKKSPLAHHYTNATFIAKLAYLSDIFSLLNQLNISLQGRNSNIFFVADKVQAFQKKLSLWSKRAHEERLDMFPLLSDILESSPQVKISHSVSQHLSHLANKFAEYFPEDPREGHMWVVDPFSVDPTENDVALPSHLESQLLEVSTDSTLKGQWGKLDLGSFWIVVSKEYPLLALRAFKVLLPF 542

HSP 2 Score: 37.7354 bits (86), Expect = 1.390e-13
Identity = 19/43 (44.19%), Postives = 30/43 (69.77%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQ-TVEEEMRV 687
            ++ K+LLPF+T+YL E  FS +   K+K R RL+ ++E  +RV
Sbjct:  534 RAFKVLLPFTTTYLCESGFSTVATTKTKARSRLRASLEATLRV 576
[Close]
BLAST of SCAN domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000005074.1 (SMESG000005074.1)

HSP 1 Score: 64.6994 bits (156), Expect = 6.934e-21
Identity = 41/120 (34.17%), Postives = 65/120 (54.17%), Query Frame = 2 
Query:  239 QKKIKEKSFDFLPIVGKFTDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNT---SGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            +++IK+ + D  P+  K      I +  F+ +  L + L +YFPSLN+  Y  I N      T++ L  S +E E+  ++KND   KI F+     EFW+ + K+YP LS+KA+K    F
Sbjct:    3 KRRIKDNNLDMFPLSSKLKRDSRIINTIFEILSNLEEKLQHYFPSLNIGEYDLIRNPFLNITTNQNL--SVEEEEEYAEIKNDRTLKIKFDVTNPTEFWMQISKEYPNLSVKAIKILLPF 120

HSP 2 Score: 55.4546 bits (132), Expect = 6.934e-21
Identity = 28/48 (58.33%), Postives = 39/48 (81.25%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRVFINILK 705
            +++KILLPFSTS L EL +S+L EIK+KKRERL  VE E+RV ++ ++
Sbjct:  112 KAIKILLPFSTSNLCELVYSSLTEIKNKKRERLLYVENELRVCLSTIR 159
[Close]
BLAST of SCAN domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000009617.1 (SMESG000009617.1)

HSP 1 Score: 60.077 bits (144), Expect = 1.405e-18
Identity = 40/120 (33.33%), Postives = 64/120 (53.33%), Query Frame = 2 
Query:  239 QKKIKEKSFDFLPIVGKFTDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNT---SGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            +++IK+ + D  P+  K      I +  F+ +  L + L  YFPSLN++ Y  I N      T++ L  S +E E+  ++KN    KI F+     EFW+ + K+YP LS+KA+K    F
Sbjct:    3 KRRIKDNNLDMFPLSSKLKRDSRILNTIFEILTNLEEKLQPYFPSLNISEYDWIRNPFLNITTNQNL--SVEEEEEYAEIKNYRTLKIKFDGTNPTEFWMQISKEYPNLSVKAIKILLPF 120

HSP 2 Score: 52.373 bits (124), Expect = 1.405e-18
Identity = 28/42 (66.67%), Postives = 35/42 (83.33%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRV 687
            +++KILLPFSTSYL EL +S+L EIK KKRER   VE+E+RV
Sbjct:  112 KAIKILLPFSTSYLCELAYSSLTEIK-KKRERQLCVEDELRV 152
[Close]
BLAST of SCAN domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000024543.1 (SMESG000024543.1)

HSP 1 Score: 53.5286 bits (127), Expect = 1.556e-15
Identity = 29/59 (49.15%), Postives = 41/59 (69.49%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERLQTVEEEMRVF-------INILKDQKR 717
            ++++ LLPF +SYL E  FSAL E+KSKK ERL+ ++EEMRV        IN++ D+K 
Sbjct:  322 KAIEPLLPFGSSYLCEHGFSALKEMKSKKPERLRMIDEEMRVCLSKIEPRINLICDKKN 380

HSP 2 Score: 48.521 bits (114), Expect = 1.556e-15
Identity = 34/96 (35.42%), Postives = 54/96 (56.25%), Query Frame = 2 
Query:  302 DEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            DE   +  QT++ L K+L+ YFP+L+V+  + I+      +      +E EQLIDLKND++ K    +  L EF +SL+    +LS KA++    F
Sbjct:  236 DEAPAIQGQTLKSLSKSLEKYFPNLDVSDMEWIMKPFMNFDVTNLE-EEEEQLIDLKNDLIFKRMCSEMKLSEFLLSLNNKSFQLSNKAIEPLLPF 330
[Close]
BLAST of SCAN domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000036914.1 (SMESG000036914.1)

HSP 1 Score: 77.0258 bits (188), Expect = 4.883e-15
Identity = 61/181 (33.70%), Postives = 92/181 (50.83%), Query Frame = 2 
Query:    2 SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDITXXXXXFDFRDSDWWLNGSAENIMTATSKLLSFKVKL-VHQKKIKEKSFDFLPIVGKFTDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDK 541
            SD+KTLL+HT V+   KGK+L R ++ K   I +L V  +      F+  D +  L G+  N +  TSKL  F+ KL +   K+ +  F     V     K +I      T++ L  +   YFP+LNV   + ++N     E +    + A+ LIDL+ND+V K    +  L EFWI L+K
Sbjct:  169 SDYKTLLYHTVVQWHSKGKILNRFVYEKD--ICWLPVSFLNDFFEKFN--DLNLKLQGAQGNFINITSKLKGFEEKLRLWSLKVSQSIFGSFSTVDSIPSKIQIKQEIGDTLKSLSDSFLKYFPNLNVTEMEWVVNPFSECEAINLEEELAQNLIDLRNDLVFKKIIVEYELSEFWIPLNK 345
[Close]
BLAST of SCAN domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000023009.1 (SMESG000023009.1)

HSP 1 Score: 55.4546 bits (132), Expect = 1.239e-13
Identity = 40/115 (34.78%), Postives = 60/115 (52.17%), Query Frame = 2 
Query:  245 KIKEKSFDFLPIVGKFTDKDEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*ILNTSGTHECLKFSTKEAEQLIDLKNDMVNKINFEQKGLGEFWISLDKDYPELSIKALKYCFRF 589
            K+ + +F   P V     K +I     +T++   K+   YF  L+V+  + ILN            +E EQLIDLKND++ K  F +  L EFW+SL+  YP+LS KA++    F
Sbjct:   14 KVSKLNFLSFPNVELNPSKLQIKQEIEETLKSFSKSFKKYFTHLDVSDIEMILNPFMNFNVTNLEEEEEEQLIDLKNDLIFKRMFSEMELSEFWLSLNNKYPQLSNKAIELLLPF 128

HSP 2 Score: 40.4318 bits (93), Expect = 1.239e-13
Identity = 20/33 (60.61%), Postives = 27/33 (81.82%), Query Frame = 1 
Query:  562 QSVKILLPFSTSYLYEL*FSALVEIKSKKRERL 660
            +++++LLPF +SYL E  FSAL E+KSKK ERL
Sbjct:  120 KAIELLLPFRSSYLCEHGFSALTEMKSKKLERL 152
The following BLAST results are available for this feature:
BLAST of SCAN domain-containing protein 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ZMYM61.147e-923.39zinc finger MYM-type containing 6 [Source:HGNC Sym... [more]
ZBED55.726e-825.85zinc finger BED-type containing 5 [Source:HGNC Sym... [more]
ZBED55.726e-825.85zinc finger BED-type containing 5 [Source:HGNC Sym... [more]
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Zbed57.670e-1224.55zinc finger, BED type containing 5 [Source:MGI Sym... [more]
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BLAST of SCAN domain-containing protein 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|O95789|ZMYM6_HUMAN5.510e-923.39Zinc finger MYM-type protein 6 OS=Homo sapiens OX=... [more]
sp|A4Z944|ZBED5_CANLF2.179e-726.03Zinc finger BED domain-containing protein 5 OS=Can... [more]
sp|Q49AG3|ZBED5_HUMAN2.750e-725.85Zinc finger BED domain-containing protein 5 OS=Hom... [more]
sp|A4Z943|ZBED5_BOVIN2.448e-624.89Zinc finger BED domain-containing protein 5 OS=Bos... [more]
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BLAST of SCAN domain-containing protein 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4U5TVN91.644e-1928.64Zinc finger BED domain-containing protein 5 OS=Col... [more]
A0A4U5TUJ91.655e-1928.64Zinc finger BED domain-containing protein 5 OS=Col... [more]
A0A4U5TUW71.712e-1928.64Zinc finger BED domain-containing protein 5 OS=Col... [more]
A0A0L8FUQ53.034e-1934.26Uncharacterized protein OS=Octopus bimaculoides OX... [more]
A0A3Q4HQ003.710e-1728.11Uncharacterized protein OS=Neolamprologus brichard... [more]
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSAMXT00000051422.15.481e-929.87pep primary_assembly:Astyanax_mexicanus-2.0:15:354... [more]
ENSAMXT00000044261.12.697e-831.03pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SCAN domain-containing protein 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000033301.12.457e-1725.35pep primary_assembly:ASM223467v1:24:1653567:165476... [more]
ENSORLT00000040389.13.573e-1725.35pep primary_assembly:ASM223467v1:19:265767:268275:... [more]
ENSORLT00000035512.13.632e-1725.35pep primary_assembly:ASM223467v1:11:22712371:22714... [more]
ENSORLT00000030244.19.609e-1524.20pep primary_assembly:ASM223467v1:13:28104458:28106... [more]
ENSORLT00000032459.11.390e-1324.66pep primary_assembly:ASM223467v1:8:14240678:142473... [more]
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BLAST of SCAN domain-containing protein 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000005074.16.934e-2134.17SMESG000005074.1[more]
SMESG000009617.11.405e-1833.33SMESG000009617.1[more]
SMESG000024543.11.556e-1549.15SMESG000024543.1[more]
SMESG000036914.14.883e-1533.70SMESG000036914.1[more]
SMESG000023009.11.239e-1334.78SMESG000023009.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033962 ID=SMED30033962|Name=SCAN domain-containing protein 3|organism=Schmidtea mediterranea sexual|type=transcript|length=1630bp
TTCTGATTTCAAAACTCTGCTCCACCACACAGAAGTTCGATTGCTGTTTA
AAGGAAAAGTTCTTGAGCGTGTTATACACCTCAAAACTAGAATAATTTCA
TTTCTTGAAGTTGACGATATCACNNNNNNNNNNNNNNNTTTTGATTTTCG
AGACAGTGACTGGTGGTTGAATGGATCAGCTGAAAATATTATGACGGCAA
CTTCAAAGCTTCTTTCATTCAAAGTAAAACTTGTTCATCAGAAAAAAATC
AAGGAAAAAAGCTTCGATTTTCTCCCCATCGTTGGCAAATTCACTGATAA
AGATGAAATTTCTGATCTTGCTTTCCAAACCATGGAAATGCTTTTGAAGG
CTCTCGACAATTATTTTCCCTCCTTAAACGTCAACTTTTATCAGTGAATT
TTGAATACATCTGGAACACACGAATGTCTTAAATTTTCCACGAAAGAAGC
AGAACAGCTTATTGATTTGAAAAACGACATGGTCAACAAAATTAATTTTG
AACAAAAAGGACTGGGAGAGTTTTGGATTTCTCTAGACAAGGATTATCCC
GAGTTGAGTATCAAAGCGTTAAAATATTGCTTCCGTTTTCTACATCATAC
TTATATGAACTTTGATTTTCGGCACTGGTTGAGATCAAATCAAAGAAACG
TGAAAGATTGCAGACAGTTGAGGAAGAAATGCGAGTTTTCATCAATATTC
TAAAAGACCAAAAACGAAATCTCTTACTTATCCTTCACTATTAACCAACA
AATCTGAAAGCAAAAAAATATTTCCAAAGAACCACTGAAATCATCAATAC
TGAGAACGATGTCGCCAAGTATTAAAAATGCGCATTTTATGAAAATAAAA
GAATATCGCAATCAAATCATTTGAAGAAACCGCGTATTAAAGCGTGCTAG
TTGGATGGATCATGTGGATGAATATACTCGTATACTAGCATCATCGAATC
ATTTTACACCGCAATCAGATGAAAGTACTGCATATCAGGATTGATAAAGA
CGAGGATGATGTGATAATATTTGCCACTAGAATAACAAACTGTTGCTAGC
GATCATCGGCGAGAGAATTCACTTGTTTGATCAGTGGTACCAGTGCGAAG
ACATAAGGCCAGCAATATGCAGAGTCGGCTAGATTACGGCAATAGTAATA
TACAACAACATATGGTTCTATGTACACAGTCATCCGGCTGTTAGTCACAT
GCATAGTAGTATTTGTCTAGTCGAAATCATGGCAAGAACTCTTGGCAACA
CATTCCTACACCTACACTAACATTTTCTATTAGAAATGGCAGACGACAAA
TCCTATTGCTGTTGACAAGCTACAGTATCTGTGCAAAGTCCAATACCATG
TGTTTTAATCAGTATATCATATACGCGGCCGTTTCATTGACACTTGCATC
TCAGATCCCAGTTGTCACTAATTATGACAGAATTCTTGTTAACTTTAATC
ATCTGTGCACCTGGAAATTATTCTTATTTCCCATTGTCTTATCTGCGTAT
TATGTAAGCTAGAATCACCGGTTGATTCTCTAGATCGCGTCTGTTTTCAA
AATTTGTGCCAATATTTTTGTGTACTGAAAATTCTTTAAATTATTAATTA
GTTTTTAGCAACATTTTATTATGACATGTG
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protein sequence of SMED30033962-orf-1

>SMED30033962-orf-1 ID=SMED30033962-orf-1|Name=SMED30033962-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=132bp
SDFKTLLHHTEVRLLFKGKVLERVIHLKTRIISFLEVDDIXXXXXXFDFR
DSDWWLNGSAENIMTATSKLLSFKVKLVHQKKIKEKSFDFLPIVGKFTDK
DEISDLAFQTMEMLLKALDNYFPSLNVNFYQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0003116parenchymal cell
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0046983protein dimerization activity