Protein disulfide-isomerase A5

Overview
NameProtein disulfide-isomerase A5
Smed IDSMED30033949
Length (bp)538
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein disulfide-isomerase A5 (SMED30033949) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein disulfide-isomerase A5 (SMED30033949) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30033949

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 48

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30033949h1SMcG0004839 Contig3820uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30033949h1SMcG0004839 Contig3820newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30033949h1SMcG0011708 Contig3820uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30033949h1SMcG0011708 Contig3820newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig27064newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig27064uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig12369uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig12369newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig41933newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig41933uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig3820uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig3820newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0011708 Contig3820uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0011708 Contig3820newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig50702uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig50702newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig5038GPL15192PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig36861newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig36861uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig4522uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig4522newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0020356 Contig4522uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0020356 Contig4522newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0000877 Contig5753newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0000877 Contig5753uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30033949h1SMcG0004839 dd_Smed_v4_1537_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30033949h1SMcG0004839 dd_Smed_v4_1537_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30033949h1SMcG0004839 dd_Smed_v4_1537_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30033949h1SMcG0004839 dd_Smed_v4_1537_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30033949h1SMcG0004839 dd_Smed_v4_1537_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30033949h1SMcG0004839 dd_Smed_v4_1537_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30033949h1SMcG0004839 dd_Smed_v4_1537_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30033949h1SMcG0004839 dd_Smed_v4_1537_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30033949h1SMcG0004839 dd_Smed_v4_1537_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30033949h1SMcG0004839 dd_Smed_v4_2070_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30033949h1SMcG0004839 dd_Smed_v4_2070_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30033949h1SMcG0004839 dd_Smed_v4_2070_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30033949h1SMcG0004839 dd_Smed_v4_2070_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30033949h1SMcG0004839 dd_Smed_v4_2070_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig5753newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033949h1SMcG0004839 Contig5753uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Category 2 cellSMED30033949h1SMcG0004839 dd_Smed_v6_1537_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30033949h1SMcG0004839 dd_Smed_v6_1537_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Category 3 cellSMED30033949h1SMcG0004839 dd_Smed_v6_1537_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gamma neoblastSMED30033949h1SMcG0004839 dd_Smed_v6_1537_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30033949h1SMcG0004839 dd_Smed_v6_1537_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30033949h1SMcG0004839 dd_Smed_v6_1537_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
secretory systemSMED30033949h1SMcG0004839 dd_Smed_v6_1537_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Human
Match: PDIA5 (protein disulfide isomerase family A member 5 [Source:HGNC Symbol;Acc:HGNC:24811])

HSP 1 Score: 100.908 bits (250), Expect = 8.094e-26
Identity = 54/153 (35.29%), Postives = 85/153 (55.56%), Query Frame = 1
Query:   97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            + D  ++KK+L + +N+LV++ + +    N L +L  V         +  V+C D  S+KLCK  K     K K  E+ H+  G F+  Y+R    +SI+ FL+DP G   WEED  A+D+VH+   +D +RL+   K     +++MFYAPWC
Sbjct:   33 ISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLL---KKEEKPLLIMFYAPWC 182          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Human
Match: PDIA5 (protein disulfide isomerase family A member 5 [Source:HGNC Symbol;Acc:HGNC:24811])

HSP 1 Score: 100.138 bits (248), Expect = 2.632e-24
Identity = 58/176 (32.95%), Postives = 94/176 (53.41%), Query Frame = 1
Query:   37 LAATWIYI---LLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            L A W+ +   L    ++  +  + D  ++KK+L + +N+LV++ + +    N L +L  V         +  V+C D  S+KLCK  K     K K  E+ H+  G F+  Y+R    +SI+ FL+DP G   WEED  A+D+VH+   +D +RL+   K     +++MFYAPWC
Sbjct:   10 LLAIWVVLPSWLSSAKVSSLIERISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLL---KKEEKPLLIMFYAPWC 182          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Human
Match: PDIA5 (protein disulfide isomerase family A member 5 [Source:HGNC Symbol;Acc:HGNC:24811])

HSP 1 Score: 51.6026 bits (122), Expect = 6.230e-9
Identity = 23/54 (42.59%), Postives = 33/54 (61.11%), Query Frame = 1
Query:  289 AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHV 450
             K K  E+ H+  G F+  Y+R    +SI+ FL+DP G   WEED  A+D+VH+
Sbjct:    7 PKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHL 60          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Fly
Match: CG9302 (gene:FBgn0032514 transcript:FBtr0080470)

HSP 1 Score: 112.079 bits (279), Expect = 6.645e-29
Identity = 53/177 (29.94%), Postives = 93/177 (52.54%), Query Frame = 1
Query:   31 MNLAATWIYILLLQIINCK--LFEVQDK----NEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNC--HDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            M +   ++++LL+ ++  K     VQD      + KK+L + +N+L +++   K     L + +E          +L+++C   D KKLCK  K  P  Y + H+  G F+K YDR+    S++ F+ DP+G++ WEED   +D++H     D      + + +I  M++MFY PWC
Sbjct:    1 MWITGQFVFLLLVALVAAKSKTSAVQDDIAEYKDFKKLLRTKNNVLALYVTSAKSAAAELKIFREAAEAIRGTGTMLLLDCGQQDRKKLCKKLKVSPDPYAIKHYKDGDFHKDYDRQLSVSSMITFMRDPSGDLPWEEDPAGKDVLHF---SDAASFTKHLRKDIRPMLVMFYVPWC 174          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Zebrafish
Match: pdia5 (protein disulfide isomerase family A, member 5 [Source:ZFIN;Acc:ZDB-GENE-030521-5])

HSP 1 Score: 98.5969 bits (244), Expect = 6.091e-24
Identity = 52/153 (33.99%), Postives = 84/153 (54.90%), Query Frame = 1
Query:   97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYKAKP----KSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            V D  + KK+L + +N+LV++ +        L +L +V         +  VNC DS  +KLCK  K  P    K  E+ H+  G F+  Y+R    +S++ FL+DP G   WEE+  A+D+VH++  +D ++L+   +  I   ++MFYAPWC
Sbjct:   41 VNDHKDFKKLLRTRTNVLVLYTKSASSGDAHLKLLSDVAQAVKGQGTIAWVNCGDSEGRKLCKKVKVDPSSKTKGVELLHYKDGTFHTEYNRPATIKSMVAFLKDPAGAPLWEENPEAKDVVHIESEKDFRKLLKREERPI---LMMFYAPWC 190          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Mouse
Match: Pdia5 (protein disulfide isomerase associated 5 [Source:MGI Symbol;Acc:MGI:1919849])

HSP 1 Score: 102.834 bits (255), Expect = 1.577e-25
Identity = 55/153 (35.95%), Postives = 85/153 (55.56%), Query Frame = 1
Query:   97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            + D  ++KK+L + +N+LV++ E +    + L +L  V         +  V+C D  S+KLCK  K     K K  E+ H+  G F+  YDR    +SI+ FL+DP G   WEED  A+D+VH+   +D +RL+   K     +++MFYAPWC
Sbjct:   31 ISDPKDLKKLLRTRNNVLVLYSESEVAAESHLKLLSTVAQAVKGQGTVCWVDCGDAESRKLCKKMKVDLSPKDKKIELFHYQDGAFHMQYDRAVTLKSIVAFLKDPKGPPLWEEDPGAKDVVHIDSEKDFRRLL---KREEKPLLMMFYAPWC 180          
BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Match: sp|Q5I0H9|PDIA5_RAT (Protein disulfide-isomerase A5 OS=Rattus norvegicus OX=10116 GN=Pdia5 PE=2 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 1.009e-24
Identity = 55/153 (35.95%), Postives = 85/153 (55.56%), Query Frame = 1
Query:   97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            + D  ++KK+L + +N+LV++ E +    + L +L  V         +  V+C D  S+KLCK  K     K K  E+ H+  G F+  YDR    +SI+ FL+DP G   WEED  A+D+VH+   +D +RL+   K     +++MFYAPWC
Sbjct:   31 ISDPKDLKKLLRTRNNVLVLYSESEVAAESHLKLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKIELFHYQDGAFHMQYDRAVTLKSIVAFLKDPKGPPLWEEDPGAKDVVHIDSEKDFRRLL---KKEEKPLLMMFYAPWC 180          
BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Match: sp|Q921X9|PDIA5_MOUSE (Protein disulfide-isomerase A5 OS=Mus musculus OX=10090 GN=Pdia5 PE=1 SV=1)

HSP 1 Score: 102.834 bits (255), Expect = 1.103e-24
Identity = 55/153 (35.95%), Postives = 85/153 (55.56%), Query Frame = 1
Query:   97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            + D  ++KK+L + +N+LV++ E +    + L +L  V         +  V+C D  S+KLCK  K     K K  E+ H+  G F+  YDR    +SI+ FL+DP G   WEED  A+D+VH+   +D +RL+   K     +++MFYAPWC
Sbjct:   31 ISDPKDLKKLLRTRNNVLVLYSESEVAAESHLKLLSTVAQAVKGQGTVCWVDCGDAESRKLCKKMKVDLSPKDKKIELFHYQDGAFHMQYDRAVTLKSIVAFLKDPKGPPLWEEDPGAKDVVHIDSEKDFRRLL---KREEKPLLMMFYAPWC 180          
BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Match: sp|Q2KIL5|PDIA5_BOVIN (Protein disulfide-isomerase A5 OS=Bos taurus OX=9913 GN=PDIA5 PE=2 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 4.623e-24
Identity = 54/153 (35.29%), Postives = 86/153 (56.21%), Query Frame = 1
Query:   97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            + D  ++KK+L + +N+LV++ + +    + L +L  V         +  V+C D  S+KLCK  K    AK K  E+ H+  G F+  Y+R    +SI+ FL+DP G   WEED  A+D+VH+   +D +RL+   K     +++MFYAPWC
Sbjct:   35 ISDPKDLKKLLRTRNNVLVLYSKSEAAAESHLKLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSAKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHIDNEKDFRRLL---KKEEKPILMMFYAPWC 184          
BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Match: sp|Q14554|PDIA5_HUMAN (Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 1.264e-23
Identity = 58/176 (32.95%), Postives = 94/176 (53.41%), Query Frame = 1
Query:   37 LAATWIYI---LLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            L A W+ +   L    ++  +  + D  ++KK+L + +N+LV++ + +    N L +L  V         +  V+C D  S+KLCK  K     K K  E+ H+  G F+  Y+R    +SI+ FL+DP G   WEED  A+D+VH+   +D +RL+   K     +++MFYAPWC
Sbjct:   10 LLAIWVVLPSWLSSAKVSSLIERISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLL---KKEEKPLLIMFYAPWC 182          
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: C3Y7X2 (Uncharacterized protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_207882 PE=3 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 1.527e-34
Identity = 65/152 (42.76%), Postives = 95/152 (62.50%), Query Frame = 1
Query:   88 LFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            +  V+D  E KKIL + +N+L +F + ++    +L    +V      L  L+ V+C D  +KKLCK  K+ P +YE+ H+  G FNK YDR+   +S++ FL DPTG+I WEED TA+D+VHV+  + L +LV   KT I   ++MFYAPWC
Sbjct:   23 ILTVEDHKEFKKILRTRTNVLSLFAKSERAASPILDTFAQVAEDMKGLGTLVFVDCSDKEAKKLCKKVKSNPDTYELKHYKDGDFNKGYDRQETYKSMMNFLRDPTGDIPWEEDPTAKDVVHVESDKALNKLVKKEKTPI---LMMFYAPWC 171          
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: A0A0L8I757 (Thioredoxin domain-containing protein (Fragment) OS=Octopus bimaculoides OX=37653 GN=OCBIM_22030584mg PE=4 SV=1)

HSP 1 Score: 127.487 bits (319), Expect = 1.537e-33
Identity = 57/147 (38.78%), Postives = 96/147 (65.31%), Query Frame = 1
Query:   97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            V+D  + KK+L + +N+LV+  + +K   ++L V++    +    A L+ ++C  +KKLC+  K    S+++ H+H G+FN+ YDRK   +S+++FL+DP G+I W+ED  A +IVHV+  Q L +++   K  +P M+LMFYAPWC
Sbjct:   38 VEDLKDFKKLLRTKTNLLVILTKTEKSLSSILPVIQTTAEEMKGKATLITIDCSVAKKLCRKLKMSSNSFDIKHYHDGEFNRNYDRKLTVKSMIKFLQDPKGDIPWDEDPEAENIVHVESEQKLNKMLK--KQRLP-MLLMFYAPWC 181          
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: A0A2T7PR44 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_02829 PE=4 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 1.326e-31
Identity = 58/147 (39.46%), Postives = 93/147 (63.27%), Query Frame = 1
Query:   97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            V+D  + KK+L + +N+LV+F + +K     +++ ++V  +    A +  VNC D KK CK  K  P ++E+ H+  G+FNK YDRK  A+S++ FL DPTG+I W+ED TA D++H+     L +L+   K +  + ++MFYAPWC
Sbjct:   24 VEDFKDFKKLLRTRTNLLVIFAQSEKSASKSMTLFEQVAEEMKGKATIAFVNCGDDKKFCKKLKINPDTFELKHYKDGEFNKDYDRKLAAKSMVNFLMDPTGDIPWDEDPTAVDVIHIDSEDGLNKLL---KKDKAATLVMFYAPWC 167          
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: A0A0B6Z5K1 (Uncharacterized protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF46665 PE=4 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 9.854e-31
Identity = 59/150 (39.33%), Postives = 91/150 (60.67%), Query Frame = 1
Query:   88 LFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            + +V+D  + KK+L + +N+LV+  + +K    V+ + +EV  +    A L  ++C D KK CK  K  P  +E+ H+  G+FNK YDRK   +S++ FL DPTGE+ WEED TA D++H+     LQ+ +   K  I   ++MFYAPWC
Sbjct:   38 IIKVEDYKDFKKLLRTKTNLLVICAQSEKATAKVMKLFEEVAEEMKGKATLGYISCEDDKKFCKKLKFSPTEFELKHYKDGEFNKDYDRKLTLKSMVNFLLDPTGELPWEEDPTATDVIHLSTEDSLQKFLKKEKHPI---LIMFYAPWC 184          
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: A0A2C9LIH2 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106070869 PE=4 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 7.892e-30
Identity = 56/150 (37.33%), Postives = 89/150 (59.33%), Query Frame = 1
Query:   88 LFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            +  + D  E KK+L + +N+LV+  + +K    V  + +EV  +    A L  +NC D KK+CK  K  P ++++ H+  G++NK YDRK   +S++ FL DPTG++ WEED TA D+VH+       +L+   K     +++MFYAPWC
Sbjct:   41 IIRIDDVKEFKKVLRTKTNLLVICSQSEKATAKVSHIFEEVAEEMKGKATLAYINCGDDKKVCKQLKVTPTTFDLRHYKDGEYNKDYDRKLAVKSMVNFLLDPTGDLPWEEDPTAVDVVHITSEDSFSKLLKRDKN---PLLVMFYAPWC 187          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Cavefish
Match: pdia5 (protein disulfide isomerase family A member 5 [Source:NCBI gene;Acc:103026706])

HSP 1 Score: 102.834 bits (255), Expect = 1.294e-25
Identity = 53/153 (34.64%), Postives = 86/153 (56.21%), Query Frame = 1
Query:   97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            V D  + KK+L + +N+LV++ +        L +L +V         +  VNC DS  +KLCK  K    +KP  +E+ H+  G F+  Y R    +S++ FL+DPTG   WEE+  A+D+VH++  +D ++L+   +  I   ++MFYAPWC
Sbjct:   42 VSDHKDFKKLLRTRTNVLVLYTKSGTSGDRQLKLLSDVAQAVKGQGTIAWVNCGDSEGRKLCKKVKVDPGSKPAGFEILHYKDGTFHTEYSRPATLKSMVAFLKDPTGAPLWEENPEAKDVVHIETEKDFRKLLKREERPI---LMMFYAPWC 191          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Cavefish
Match: pdia5 (protein disulfide isomerase family A member 5 [Source:NCBI gene;Acc:103026706])

HSP 1 Score: 85.1149 bits (209), Expect = 2.642e-19
Identity = 49/172 (28.49%), Postives = 90/172 (52.33%), Query Frame = 1
Query:   52 IYILLLQIINCKLF--EVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMML--MFYAPWC 537
            +++  LQ +       +V D  + KK+L + +N+LV++ +        L +L +V         +  VNC DS  +KLCK  K    +KP  +E+ H+  G F+  Y R    +S++ FL+DPTG   WEE+  A+D+VH+    + +++  +F+  + + +   + +A WC
Sbjct:   19 VFVSTLQAVKVSPLIEKVSDHKDFKKLLRTRTNVLVLYTKSGTSGDRQLKLLSDVAQAVKGQGTIAWVNCGDSEGRKLCKKVKVDPGSKPAGFEILHYKDGTFHTEYSRPATLKSMVAFLKDPTGAPLWEENPEAKDVVHI----ETEKVSISFRRRLWTEITFPLVFAWWC 186          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006474.1 (pep scaffold:Pmarinus_7.0:GL478000:14574:47610:1 gene:ENSPMAG00000005827.1 transcript:ENSPMAT00000006474.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.9669 bits (219), Expect = 2.436e-21
Identity = 48/148 (32.43%), Postives = 86/148 (58.11%), Query Frame = 1
Query:  103 DKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYKAKPK-SYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            D  E++KI+ + +N+LV++ + +      L +L +V         +  V+C +S  +KLCK  K +P  + ++ H+  G+F+  YDR    +S++ F+ DPTG+  WEE+  A+D+VHV   ++ + L+   K     +++MFYAPWC
Sbjct:   40 DHKELRKIIRTRNNVLVLYHQGESGLDKKLKLLSDVGQAVRGSGTVAWVDCGNSEGRKLCKKMKVEPGGTSKLMHYKDGEFHVEYDRAETFKSLVAFMYDPTGDPLWEEEPDAKDVVHVHSDKEFRLLL---KKEERPILMMFYAPWC 184          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Sea Lamprey
Match: pdia5 (protein disulfide isomerase family A, member 5 [Source:ZFIN;Acc:ZDB-GENE-030521-5])

HSP 1 Score: 79.7221 bits (195), Expect = 4.169e-18
Identity = 45/152 (29.61%), Postives = 76/152 (50.00%), Query Frame = 1
Query:   94 EVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYKAKPKS--YEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            +V D   +++++ S +N+LV++        + L +L+ V +     A +  +NC +    + C   K  P +   E+ H+  G F+  Y R    +S+  FL DP G   WE+  +ARD+ H+   Q+ + LV N    I    +MFYAPWC
Sbjct:   55 KVTDIQSLRQLIRSRNNLLVLYATSALAAQDTLVLLERVADAVAGAATVAWINCGEEGGAEACARMKVVPDADGVELLHYRDGAFHIEYTRPETFKSMTAFLRDPLGAPLWEDSPSARDVKHLTTDQEFRTLVKNEARPI---FIMFYAPWC 203          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Nematostella
Match: EDO41376 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4E6])

HSP 1 Score: 117.857 bits (294), Expect = 1.472e-31
Identity = 57/148 (38.51%), Postives = 90/148 (60.81%), Query Frame = 1
Query:   94 EVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            EV D    KK+L ++ N+LV+F + +K     LS+L EV         +  +NC DSKKLCK +K  PK   + H+ +G FNK YDR    +S++ F+ +PTG+  WEE+  + D+VH++ + +L +L++  K  +   ++MFYAPWC
Sbjct:    3 EVNDVKPFKKLLRTNKNLLVLFAKSEKDASKKLSLLGEVAMAIKGKGTVAFINCGDSKKLCKKFKVSPKPLALKHYKEGDFNKDYDRLDTFKSMMTFMNNPTGDAPWEEEPGSSDVVHLEKAGELSKLLTREKKPV---LIMFYAPWC 147          

HSP 2 Score: 44.669 bits (104), Expect = 7.684e-6
Identity = 22/79 (27.85%), Postives = 43/79 (54.43%), Query Frame = 1
Query:  316 HFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDE-----TARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            +F  G+    Y  K   ++++++++DP+     +EDE     T  ++VH++       +  +F    PS+++MFYAPWC
Sbjct:  197 YFELGQPKYKYSGKHEKDALVQWMKDPSAVAPVKEDEKPWSDTPSEVVHLR-----DDMFDDFVAKNPSVLVMFYAPWC 270          
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Medaka
Match: pdia5 (protein disulfide isomerase family A member 5 [Source:NCBI gene;Acc:101175203])

HSP 1 Score: 97.0561 bits (240), Expect = 1.508e-23
Identity = 51/154 (33.12%), Postives = 87/154 (56.49%), Query Frame = 1
Query:   94 EVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYKAKPKS----YEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            +V D  + KK+L + +N+LV++ +      + L +L +V         +  VNC DS  +KLCK  K  P S     E+ H+  G F+  Y+R    +S++ FL+DP+G   WEE+  A+D+VH++  ++ ++L+   K     +++MFYAPWC
Sbjct:   70 KVGDHKDFKKLLRTRTNVLVLYTKTATSGDSHLKLLSDVAQTVKGQGTIAWVNCGDSEGRKLCKKVKVDPSSKQGGIELLHYKDGTFHTEYNRPTTIKSMVAFLKDPSGPPLWEENPEAKDVVHIETEKEFRKLL---KKEEKPVLMMFYAPWC 220          
BLAST of Protein disulfide-isomerase A5 vs. Planmine SMEST
Match: SMESG000005268.1 (SMESG000005268.1)

HSP 1 Score: 353.984 bits (907), Expect = 2.243e-119
Identity = 169/169 (100.00%), Postives = 169/169 (100.00%), Query Frame = 1
Query:   31 MNLAATWIYILLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537
            MNLAATWIYILLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC
Sbjct:    1 MNLAATWIYILLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 169          
The following BLAST results are available for this feature:
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
PDIA58.094e-2635.29protein disulfide isomerase family A member 5 [Sou... [more]
PDIA52.632e-2432.95protein disulfide isomerase family A member 5 [Sou... [more]
PDIA56.230e-942.59protein disulfide isomerase family A member 5 [Sou... [more]
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG93026.645e-2929.94gene:FBgn0032514 transcript:FBtr0080470[more]
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pdia56.091e-2433.99protein disulfide isomerase family A, member 5 [So... [more]
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Pdia51.577e-2535.95protein disulfide isomerase associated 5 [Source:M... [more]
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BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q5I0H9|PDIA5_RAT1.009e-2435.95Protein disulfide-isomerase A5 OS=Rattus norvegicu... [more]
sp|Q921X9|PDIA5_MOUSE1.103e-2435.95Protein disulfide-isomerase A5 OS=Mus musculus OX=... [more]
sp|Q2KIL5|PDIA5_BOVIN4.623e-2435.29Protein disulfide-isomerase A5 OS=Bos taurus OX=99... [more]
sp|Q14554|PDIA5_HUMAN1.264e-2332.95Protein disulfide-isomerase A5 OS=Homo sapiens OX=... [more]
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BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
C3Y7X21.527e-3442.76Uncharacterized protein (Fragment) OS=Branchiostom... [more]
A0A0L8I7571.537e-3338.78Thioredoxin domain-containing protein (Fragment) O... [more]
A0A2T7PR441.326e-3139.46Uncharacterized protein OS=Pomacea canaliculata OX... [more]
A0A0B6Z5K19.854e-3139.33Uncharacterized protein (Fragment) OS=Arion vulgar... [more]
A0A2C9LIH27.892e-3037.33Uncharacterized protein OS=Biomphalaria glabrata O... [more]
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pdia51.294e-2534.64protein disulfide isomerase family A member 5 [Sou... [more]
pdia52.642e-1928.49protein disulfide isomerase family A member 5 [Sou... [more]
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000006474.12.436e-2132.43pep scaffold:Pmarinus_7.0:GL478000:14574:47610:1 g... [more]
pdia54.169e-1829.61protein disulfide isomerase family A, member 5 [So... [more]
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO413761.472e-3138.51Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein disulfide-isomerase A5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pdia51.508e-2333.12protein disulfide isomerase family A member 5 [Sou... [more]
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BLAST of Protein disulfide-isomerase A5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000005268.12.243e-119100.00SMESG000005268.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033949 ID=SMED30033949|Name=Protein disulfide-isomerase A5|organism=Schmidtea mediterranea sexual|type=transcript|length=538bp
CAGATTTTGTGACATAATTTCAAATTTCAAATGAATCTCGCGGCGACGTG
GATTTATATATTACTTTTACAAATTATTAACTGCAAACTATTCGAGGTTC
AAGATAAAAATGAAATGAAAAAAATTCTTATGTCGCATTCAAATATATTA
GTTGTTTTTATCGAAGATGACAAAGTTGATGGAAATGTTTTGTCAGTATT
AAAAGAAGTAGTGAATAAAGGCAACAAATTAGCAAAACTGTTAATTGTTA
ATTGCCATGATAGCAAGAAATTATGTAAACATTATAAAGCTAAGCCAAAA
TCCTATGAAATGCATCATTTTCACAAGGGTAAATTCAACAAATTATACGA
CAGAAAATTCAGGGCTGAGTCGATTCTGCGATTCCTCGAAGATCCTACGG
GAGAAATAGCCTGGGAGGAGGACGAAACTGCCAGAGACATTGTGCACGTC
AAGGGCTCGCAGGACCTCCAGCGGCTTGTCAGCAATTTCAAGACCAATAT
TCCATCAATGATGCTCATGTTCTATGCTCCATGGTGCG
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protein sequence of SMED30033949-orf-1

>SMED30033949-orf-1 ID=SMED30033949-orf-1|Name=SMED30033949-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=169bp
MNLAATWIYILLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVD
GNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKG
KFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLV
SNFKTNIPSMMLMFYAPWC
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003756protein disulfide isomerase activity
GO:0016853isomerase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000499cell
Vocabulary: INTERPRO
TermDefinition
IPR036249Thioredoxin-like_sf
IPR012336Thioredoxin-like_fold
Vocabulary: biological process
TermDefinition
GO:0045454cell redox homeostasis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR036249Thioredoxin-like superfamilyGENE3DG3DSA:3.40.30.10coord: 19..142
e-value: 8.8E-20
score: 72.9
IPR036249Thioredoxin-like superfamilySUPERFAMILYSSF52833Thioredoxin-likecoord: 22..124
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..18
score: 0.69