Protein disulfide-isomerase A5
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033949 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 48Note: Hover over icons to view figure legend
Homology
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Human
Match: PDIA5 (protein disulfide isomerase family A member 5 [Source:HGNC Symbol;Acc:HGNC:24811]) HSP 1 Score: 100.908 bits (250), Expect = 8.094e-26 Identity = 54/153 (35.29%), Postives = 85/153 (55.56%), Query Frame = 1 Query: 97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 + D ++KK+L + +N+LV++ + + N L +L V + V+C D S+KLCK K K K E+ H+ G F+ Y+R +SI+ FL+DP G WEED A+D+VH+ +D +RL+ K +++MFYAPWC Sbjct: 33 ISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLL---KKEEKPLLIMFYAPWC 182
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Human
Match: PDIA5 (protein disulfide isomerase family A member 5 [Source:HGNC Symbol;Acc:HGNC:24811]) HSP 1 Score: 100.138 bits (248), Expect = 2.632e-24 Identity = 58/176 (32.95%), Postives = 94/176 (53.41%), Query Frame = 1 Query: 37 LAATWIYI---LLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 L A W+ + L ++ + + D ++KK+L + +N+LV++ + + N L +L V + V+C D S+KLCK K K K E+ H+ G F+ Y+R +SI+ FL+DP G WEED A+D+VH+ +D +RL+ K +++MFYAPWC Sbjct: 10 LLAIWVVLPSWLSSAKVSSLIERISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLL---KKEEKPLLIMFYAPWC 182
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Human
Match: PDIA5 (protein disulfide isomerase family A member 5 [Source:HGNC Symbol;Acc:HGNC:24811]) HSP 1 Score: 51.6026 bits (122), Expect = 6.230e-9 Identity = 23/54 (42.59%), Postives = 33/54 (61.11%), Query Frame = 1 Query: 289 AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHV 450 K K E+ H+ G F+ Y+R +SI+ FL+DP G WEED A+D+VH+ Sbjct: 7 PKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHL 60
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Fly
Match: CG9302 (gene:FBgn0032514 transcript:FBtr0080470) HSP 1 Score: 112.079 bits (279), Expect = 6.645e-29 Identity = 53/177 (29.94%), Postives = 93/177 (52.54%), Query Frame = 1 Query: 31 MNLAATWIYILLLQIINCK--LFEVQDK----NEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNC--HDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 M + ++++LL+ ++ K VQD + KK+L + +N+L +++ K L + +E +L+++C D KKLCK K P Y + H+ G F+K YDR+ S++ F+ DP+G++ WEED +D++H D + + +I M++MFY PWC Sbjct: 1 MWITGQFVFLLLVALVAAKSKTSAVQDDIAEYKDFKKLLRTKNNVLALYVTSAKSAAAELKIFREAAEAIRGTGTMLLLDCGQQDRKKLCKKLKVSPDPYAIKHYKDGDFHKDYDRQLSVSSMITFMRDPSGDLPWEEDPAGKDVLHF---SDAASFTKHLRKDIRPMLVMFYVPWC 174
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Zebrafish
Match: pdia5 (protein disulfide isomerase family A, member 5 [Source:ZFIN;Acc:ZDB-GENE-030521-5]) HSP 1 Score: 98.5969 bits (244), Expect = 6.091e-24 Identity = 52/153 (33.99%), Postives = 84/153 (54.90%), Query Frame = 1 Query: 97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYKAKP----KSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 V D + KK+L + +N+LV++ + L +L +V + VNC DS +KLCK K P K E+ H+ G F+ Y+R +S++ FL+DP G WEE+ A+D+VH++ +D ++L+ + I ++MFYAPWC Sbjct: 41 VNDHKDFKKLLRTRTNVLVLYTKSASSGDAHLKLLSDVAQAVKGQGTIAWVNCGDSEGRKLCKKVKVDPSSKTKGVELLHYKDGTFHTEYNRPATIKSMVAFLKDPAGAPLWEENPEAKDVVHIESEKDFRKLLKREERPI---LMMFYAPWC 190
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Mouse
Match: Pdia5 (protein disulfide isomerase associated 5 [Source:MGI Symbol;Acc:MGI:1919849]) HSP 1 Score: 102.834 bits (255), Expect = 1.577e-25 Identity = 55/153 (35.95%), Postives = 85/153 (55.56%), Query Frame = 1 Query: 97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 + D ++KK+L + +N+LV++ E + + L +L V + V+C D S+KLCK K K K E+ H+ G F+ YDR +SI+ FL+DP G WEED A+D+VH+ +D +RL+ K +++MFYAPWC Sbjct: 31 ISDPKDLKKLLRTRNNVLVLYSESEVAAESHLKLLSTVAQAVKGQGTVCWVDCGDAESRKLCKKMKVDLSPKDKKIELFHYQDGAFHMQYDRAVTLKSIVAFLKDPKGPPLWEEDPGAKDVVHIDSEKDFRRLL---KREEKPLLMMFYAPWC 180
BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Match: sp|Q5I0H9|PDIA5_RAT (Protein disulfide-isomerase A5 OS=Rattus norvegicus OX=10116 GN=Pdia5 PE=2 SV=1) HSP 1 Score: 103.219 bits (256), Expect = 1.009e-24 Identity = 55/153 (35.95%), Postives = 85/153 (55.56%), Query Frame = 1 Query: 97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 + D ++KK+L + +N+LV++ E + + L +L V + V+C D S+KLCK K K K E+ H+ G F+ YDR +SI+ FL+DP G WEED A+D+VH+ +D +RL+ K +++MFYAPWC Sbjct: 31 ISDPKDLKKLLRTRNNVLVLYSESEVAAESHLKLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKIELFHYQDGAFHMQYDRAVTLKSIVAFLKDPKGPPLWEEDPGAKDVVHIDSEKDFRRLL---KKEEKPLLMMFYAPWC 180
BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Match: sp|Q921X9|PDIA5_MOUSE (Protein disulfide-isomerase A5 OS=Mus musculus OX=10090 GN=Pdia5 PE=1 SV=1) HSP 1 Score: 102.834 bits (255), Expect = 1.103e-24 Identity = 55/153 (35.95%), Postives = 85/153 (55.56%), Query Frame = 1 Query: 97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 + D ++KK+L + +N+LV++ E + + L +L V + V+C D S+KLCK K K K E+ H+ G F+ YDR +SI+ FL+DP G WEED A+D+VH+ +D +RL+ K +++MFYAPWC Sbjct: 31 ISDPKDLKKLLRTRNNVLVLYSESEVAAESHLKLLSTVAQAVKGQGTVCWVDCGDAESRKLCKKMKVDLSPKDKKIELFHYQDGAFHMQYDRAVTLKSIVAFLKDPKGPPLWEEDPGAKDVVHIDSEKDFRRLL---KREEKPLLMMFYAPWC 180
BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Match: sp|Q2KIL5|PDIA5_BOVIN (Protein disulfide-isomerase A5 OS=Bos taurus OX=9913 GN=PDIA5 PE=2 SV=1) HSP 1 Score: 101.293 bits (251), Expect = 4.623e-24 Identity = 54/153 (35.29%), Postives = 86/153 (56.21%), Query Frame = 1 Query: 97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 + D ++KK+L + +N+LV++ + + + L +L V + V+C D S+KLCK K AK K E+ H+ G F+ Y+R +SI+ FL+DP G WEED A+D+VH+ +D +RL+ K +++MFYAPWC Sbjct: 35 ISDPKDLKKLLRTRNNVLVLYSKSEAAAESHLKLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSAKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHIDNEKDFRRLL---KKEEKPILMMFYAPWC 184
BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Match: sp|Q14554|PDIA5_HUMAN (Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1) HSP 1 Score: 100.138 bits (248), Expect = 1.264e-23 Identity = 58/176 (32.95%), Postives = 94/176 (53.41%), Query Frame = 1 Query: 37 LAATWIYI---LLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 L A W+ + L ++ + + D ++KK+L + +N+LV++ + + N L +L V + V+C D S+KLCK K K K E+ H+ G F+ Y+R +SI+ FL+DP G WEED A+D+VH+ +D +RL+ K +++MFYAPWC Sbjct: 10 LLAIWVVLPSWLSSAKVSSLIERISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLL---KKEEKPLLIMFYAPWC 182
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: C3Y7X2 (Uncharacterized protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_207882 PE=3 SV=1) HSP 1 Score: 136.732 bits (343), Expect = 1.527e-34 Identity = 65/152 (42.76%), Postives = 95/152 (62.50%), Query Frame = 1 Query: 88 LFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHD--SKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 + V+D E KKIL + +N+L +F + ++ +L +V L L+ V+C D +KKLCK K+ P +YE+ H+ G FNK YDR+ +S++ FL DPTG+I WEED TA+D+VHV+ + L +LV KT I ++MFYAPWC Sbjct: 23 ILTVEDHKEFKKILRTRTNVLSLFAKSERAASPILDTFAQVAEDMKGLGTLVFVDCSDKEAKKLCKKVKSNPDTYELKHYKDGDFNKGYDRQETYKSMMNFLRDPTGDIPWEEDPTAKDVVHVESDKALNKLVKKEKTPI---LMMFYAPWC 171
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: A0A0L8I757 (Thioredoxin domain-containing protein (Fragment) OS=Octopus bimaculoides OX=37653 GN=OCBIM_22030584mg PE=4 SV=1) HSP 1 Score: 127.487 bits (319), Expect = 1.537e-33 Identity = 57/147 (38.78%), Postives = 96/147 (65.31%), Query Frame = 1 Query: 97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 V+D + KK+L + +N+LV+ + +K ++L V++ + A L+ ++C +KKLC+ K S+++ H+H G+FN+ YDRK +S+++FL+DP G+I W+ED A +IVHV+ Q L +++ K +P M+LMFYAPWC Sbjct: 38 VEDLKDFKKLLRTKTNLLVILTKTEKSLSSILPVIQTTAEEMKGKATLITIDCSVAKKLCRKLKMSSNSFDIKHYHDGEFNRNYDRKLTVKSMIKFLQDPKGDIPWDEDPEAENIVHVESEQKLNKMLK--KQRLP-MLLMFYAPWC 181
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: A0A2T7PR44 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_02829 PE=4 SV=1) HSP 1 Score: 130.183 bits (326), Expect = 1.326e-31 Identity = 58/147 (39.46%), Postives = 93/147 (63.27%), Query Frame = 1 Query: 97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 V+D + KK+L + +N+LV+F + +K +++ ++V + A + VNC D KK CK K P ++E+ H+ G+FNK YDRK A+S++ FL DPTG+I W+ED TA D++H+ L +L+ K + + ++MFYAPWC Sbjct: 24 VEDFKDFKKLLRTRTNLLVIFAQSEKSASKSMTLFEQVAEEMKGKATIAFVNCGDDKKFCKKLKINPDTFELKHYKDGEFNKDYDRKLAAKSMVNFLMDPTGDIPWDEDPTAVDVIHIDSEDGLNKLL---KKDKAATLVMFYAPWC 167
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: A0A0B6Z5K1 (Uncharacterized protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF46665 PE=4 SV=1) HSP 1 Score: 126.716 bits (317), Expect = 9.854e-31 Identity = 59/150 (39.33%), Postives = 91/150 (60.67%), Query Frame = 1 Query: 88 LFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 + +V+D + KK+L + +N+LV+ + +K V+ + +EV + A L ++C D KK CK K P +E+ H+ G+FNK YDRK +S++ FL DPTGE+ WEED TA D++H+ LQ+ + K I ++MFYAPWC Sbjct: 38 IIKVEDYKDFKKLLRTKTNLLVICAQSEKATAKVMKLFEEVAEEMKGKATLGYISCEDDKKFCKKLKFSPTEFELKHYKDGEFNKDYDRKLTLKSMVNFLLDPTGELPWEEDPTATDVIHLSTEDSLQKFLKKEKHPI---LIMFYAPWC 184
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Match: A0A2C9LIH2 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106070869 PE=4 SV=1) HSP 1 Score: 125.176 bits (313), Expect = 7.892e-30 Identity = 56/150 (37.33%), Postives = 89/150 (59.33%), Query Frame = 1 Query: 88 LFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 + + D E KK+L + +N+LV+ + +K V + +EV + A L +NC D KK+CK K P ++++ H+ G++NK YDRK +S++ FL DPTG++ WEED TA D+VH+ +L+ K +++MFYAPWC Sbjct: 41 IIRIDDVKEFKKVLRTKTNLLVICSQSEKATAKVSHIFEEVAEEMKGKATLAYINCGDDKKVCKQLKVTPTTFDLRHYKDGEYNKDYDRKLAVKSMVNFLLDPTGDLPWEEDPTAVDVVHITSEDSFSKLLKRDKN---PLLVMFYAPWC 187
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Cavefish
Match: pdia5 (protein disulfide isomerase family A member 5 [Source:NCBI gene;Acc:103026706]) HSP 1 Score: 102.834 bits (255), Expect = 1.294e-25 Identity = 53/153 (34.64%), Postives = 86/153 (56.21%), Query Frame = 1 Query: 97 VQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 V D + KK+L + +N+LV++ + L +L +V + VNC DS +KLCK K +KP +E+ H+ G F+ Y R +S++ FL+DPTG WEE+ A+D+VH++ +D ++L+ + I ++MFYAPWC Sbjct: 42 VSDHKDFKKLLRTRTNVLVLYTKSGTSGDRQLKLLSDVAQAVKGQGTIAWVNCGDSEGRKLCKKVKVDPGSKPAGFEILHYKDGTFHTEYSRPATLKSMVAFLKDPTGAPLWEENPEAKDVVHIETEKDFRKLLKREERPI---LMMFYAPWC 191
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Cavefish
Match: pdia5 (protein disulfide isomerase family A member 5 [Source:NCBI gene;Acc:103026706]) HSP 1 Score: 85.1149 bits (209), Expect = 2.642e-19 Identity = 49/172 (28.49%), Postives = 90/172 (52.33%), Query Frame = 1 Query: 52 IYILLLQIINCKLF--EVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYK----AKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMML--MFYAPWC 537 +++ LQ + +V D + KK+L + +N+LV++ + L +L +V + VNC DS +KLCK K +KP +E+ H+ G F+ Y R +S++ FL+DPTG WEE+ A+D+VH+ + +++ +F+ + + + + +A WC Sbjct: 19 VFVSTLQAVKVSPLIEKVSDHKDFKKLLRTRTNVLVLYTKSGTSGDRQLKLLSDVAQAVKGQGTIAWVNCGDSEGRKLCKKVKVDPGSKPAGFEILHYKDGTFHTEYSRPATLKSMVAFLKDPTGAPLWEENPEAKDVVHI----ETEKVSISFRRRLWTEITFPLVFAWWC 186
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006474.1 (pep scaffold:Pmarinus_7.0:GL478000:14574:47610:1 gene:ENSPMAG00000005827.1 transcript:ENSPMAT00000006474.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.9669 bits (219), Expect = 2.436e-21 Identity = 48/148 (32.43%), Postives = 86/148 (58.11%), Query Frame = 1 Query: 103 DKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYKAKPK-SYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 D E++KI+ + +N+LV++ + + L +L +V + V+C +S +KLCK K +P + ++ H+ G+F+ YDR +S++ F+ DPTG+ WEE+ A+D+VHV ++ + L+ K +++MFYAPWC Sbjct: 40 DHKELRKIIRTRNNVLVLYHQGESGLDKKLKLLSDVGQAVRGSGTVAWVDCGNSEGRKLCKKMKVEPGGTSKLMHYKDGEFHVEYDRAETFKSLVAFMYDPTGDPLWEEEPDAKDVVHVHSDKEFRLLL---KKEERPILMMFYAPWC 184
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Sea Lamprey
Match: pdia5 (protein disulfide isomerase family A, member 5 [Source:ZFIN;Acc:ZDB-GENE-030521-5]) HSP 1 Score: 79.7221 bits (195), Expect = 4.169e-18 Identity = 45/152 (29.61%), Postives = 76/152 (50.00%), Query Frame = 1 Query: 94 EVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYKAKPKS--YEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 +V D +++++ S +N+LV++ + L +L+ V + A + +NC + + C K P + E+ H+ G F+ Y R +S+ FL DP G WE+ +ARD+ H+ Q+ + LV N I +MFYAPWC Sbjct: 55 KVTDIQSLRQLIRSRNNLLVLYATSALAAQDTLVLLERVADAVAGAATVAWINCGEEGGAEACARMKVVPDADGVELLHYRDGAFHIEYTRPETFKSMTAFLRDPLGAPLWEDSPSARDVKHLTTDQEFRTLVKNEARPI---FIMFYAPWC 203
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Nematostella
Match: EDO41376 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4E6]) HSP 1 Score: 117.857 bits (294), Expect = 1.472e-31 Identity = 57/148 (38.51%), Postives = 90/148 (60.81%), Query Frame = 1 Query: 94 EVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 EV D KK+L ++ N+LV+F + +K LS+L EV + +NC DSKKLCK +K PK + H+ +G FNK YDR +S++ F+ +PTG+ WEE+ + D+VH++ + +L +L++ K + ++MFYAPWC Sbjct: 3 EVNDVKPFKKLLRTNKNLLVLFAKSEKDASKKLSLLGEVAMAIKGKGTVAFINCGDSKKLCKKFKVSPKPLALKHYKEGDFNKDYDRLDTFKSMMTFMNNPTGDAPWEEEPGSSDVVHLEKAGELSKLLTREKKPV---LIMFYAPWC 147 HSP 2 Score: 44.669 bits (104), Expect = 7.684e-6 Identity = 22/79 (27.85%), Postives = 43/79 (54.43%), Query Frame = 1 Query: 316 HFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDE-----TARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 +F G+ Y K ++++++++DP+ +EDE T ++VH++ + +F PS+++MFYAPWC Sbjct: 197 YFELGQPKYKYSGKHEKDALVQWMKDPSAVAPVKEDEKPWSDTPSEVVHLR-----DDMFDDFVAKNPSVLVMFYAPWC 270
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Medaka
Match: pdia5 (protein disulfide isomerase family A member 5 [Source:NCBI gene;Acc:101175203]) HSP 1 Score: 97.0561 bits (240), Expect = 1.508e-23 Identity = 51/154 (33.12%), Postives = 87/154 (56.49%), Query Frame = 1 Query: 94 EVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDS--KKLCKHYKAKPKS----YEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 +V D + KK+L + +N+LV++ + + L +L +V + VNC DS +KLCK K P S E+ H+ G F+ Y+R +S++ FL+DP+G WEE+ A+D+VH++ ++ ++L+ K +++MFYAPWC Sbjct: 70 KVGDHKDFKKLLRTRTNVLVLYTKTATSGDSHLKLLSDVAQTVKGQGTIAWVNCGDSEGRKLCKKVKVDPSSKQGGIELLHYKDGTFHTEYNRPTTIKSMVAFLKDPSGPPLWEENPEAKDVVHIETEKEFRKLL---KKEEKPVLMMFYAPWC 220
BLAST of Protein disulfide-isomerase A5 vs. Planmine SMEST
Match: SMESG000005268.1 (SMESG000005268.1) HSP 1 Score: 353.984 bits (907), Expect = 2.243e-119 Identity = 169/169 (100.00%), Postives = 169/169 (100.00%), Query Frame = 1 Query: 31 MNLAATWIYILLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 537 MNLAATWIYILLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC Sbjct: 1 MNLAATWIYILLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDGNVLSVLKEVVNKGNKLAKLLIVNCHDSKKLCKHYKAKPKSYEMHHFHKGKFNKLYDRKFRAESILRFLEDPTGEIAWEEDETARDIVHVKGSQDLQRLVSNFKTNIPSMMLMFYAPWC 169 The following BLAST results are available for this feature:
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 3
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 1
BLAST of Protein disulfide-isomerase A5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of Protein disulfide-isomerase A5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Protein disulfide-isomerase A5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of Protein disulfide-isomerase A5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033949 ID=SMED30033949|Name=Protein disulfide-isomerase A5|organism=Schmidtea mediterranea sexual|type=transcript|length=538bpback to top protein sequence of SMED30033949-orf-1 >SMED30033949-orf-1 ID=SMED30033949-orf-1|Name=SMED30033949-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=169bp MNLAATWIYILLLQIINCKLFEVQDKNEMKKILMSHSNILVVFIEDDKVDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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