Cystathionine beta-synthase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033930 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 48Note: Hover over icons to view figure legend
Homology
BLAST of Cystathionine beta-synthase vs. Ensembl Human
Match: CBSL (cystathionine beta-synthase like [Source:HGNC Symbol;Acc:HGNC:51829]) HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0 Identity = 292/512 (57.03%), Postives = 384/512 (75.00%), Query Frame = 3
Query: 96 KSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
K PL + P S+CT++L + SPH PKI+ +IL IG TP+V++NKIGK + CE+L KCE+ N GGSVKDRISLRMIEDAE G +KPGDT+IEPTSGNTGIGLALAAAV+GY+CIIVMPEKMS EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TA+EIL CD +DM+V S GTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+++F AR LI +EGLLCGGS+G+ V AV+AA++ L + R VV+LPDSVRNYMTKFLSD WM + F+ + ++ + ++ L L+AP+TV P++T T+E+L+++GFDQ PVV+ +G I+GM T+G ++S L+ + +D V K IYK FK++ L T+ +LS +L++DHF LVVH+Q Q TG ++M++G+VT IDL++++
Sbjct: 39 KEPL--WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE--LQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKE---EDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFV 543
BLAST of Cystathionine beta-synthase vs. Ensembl Human
Match: CBSL (cystathionine beta-synthase like [Source:HGNC Symbol;Acc:HGNC:51829]) HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0 Identity = 292/512 (57.03%), Postives = 384/512 (75.00%), Query Frame = 3
Query: 96 KSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
K PL + P S+CT++L + SPH PKI+ +IL IG TP+V++NKIGK + CE+L KCE+ N GGSVKDRISLRMIEDAE G +KPGDT+IEPTSGNTGIGLALAAAV+GY+CIIVMPEKMS EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TA+EIL CD +DM+V S GTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+++F AR LI +EGLLCGGS+G+ V AV+AA++ L + R VV+LPDSVRNYMTKFLSD WM + F+ + ++ + ++ L L+AP+TV P++T T+E+L+++GFDQ PVV+ +G I+GM T+G ++S L+ + +D V K IYK FK++ L T+ +LS +L++DHF LVVH+Q Q TG ++M++G+VT IDL++++
Sbjct: 39 KEPL--WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE--LQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKE---EDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFV 543
BLAST of Cystathionine beta-synthase vs. Ensembl Human
Match: CBSL (cystathionine beta-synthase like [Source:HGNC Symbol;Acc:HGNC:51829]) HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0 Identity = 292/512 (57.03%), Postives = 384/512 (75.00%), Query Frame = 3
Query: 96 KSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
K PL + P S+CT++L + SPH PKI+ +IL IG TP+V++NKIGK + CE+L KCE+ N GGSVKDRISLRMIEDAE G +KPGDT+IEPTSGNTGIGLALAAAV+GY+CIIVMPEKMS EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TA+EIL CD +DM+V S GTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+++F AR LI +EGLLCGGS+G+ V AV+AA++ L + R VV+LPDSVRNYMTKFLSD WM + F+ + ++ + ++ L L+AP+TV P++T T+E+L+++GFDQ PVV+ +G I+GM T+G ++S L+ + +D V K IYK FK++ L T+ +LS +L++DHF LVVH+Q Q TG ++M++G+VT IDL++++
Sbjct: 39 KEPL--WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE--LQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKE---EDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFV 543
BLAST of Cystathionine beta-synthase vs. Ensembl Human
Match: CBSL (cystathionine beta-synthase like [Source:HGNC Symbol;Acc:HGNC:51829]) HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0 Identity = 292/512 (57.03%), Postives = 384/512 (75.00%), Query Frame = 3
Query: 96 KSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
K PL + P S+CT++L + SPH PKI+ +IL IG TP+V++NKIGK + CE+L KCE+ N GGSVKDRISLRMIEDAE G +KPGDT+IEPTSGNTGIGLALAAAV+GY+CIIVMPEKMS EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TA+EIL CD +DM+V S GTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+++F AR LI +EGLLCGGS+G+ V AV+AA++ L + R VV+LPDSVRNYMTKFLSD WM + F+ + ++ + ++ L L+AP+TV P++T T+E+L+++GFDQ PVV+ +G I+GM T+G ++S L+ + +D V K IYK FK++ L T+ +LS +L++DHF LVVH+Q Q TG ++M++G+VT IDL++++
Sbjct: 39 KEPL--WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE--LQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKE---EDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFV 543
BLAST of Cystathionine beta-synthase vs. Ensembl Human
Match: CBS (cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550]) HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0 Identity = 292/512 (57.03%), Postives = 384/512 (75.00%), Query Frame = 3
Query: 96 KSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
K PL + P S+CT++L + SPH PKI+ +IL IG TP+V++NKIGK + CE+L KCE+ N GGSVKDRISLRMIEDAE G +KPGDT+IEPTSGNTGIGLALAAAV+GY+CIIVMPEKMS EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TA+EIL CD +DM+V S GTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+++F AR LI +EGLLCGGS+G+ V AV+AA++ L + R VV+LPDSVRNYMTKFLSD WM + F+ + ++ + ++ L L+AP+TV P++T T+E+L+++GFDQ PVV+ +G I+GM T+G ++S L+ + +D V K IYK FK++ L T+ +LS +L++DHF LVVH+Q Q TG ++M++G+VT IDL++++
Sbjct: 39 KEPL--WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE--LQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKE---EDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFV 543
BLAST of Cystathionine beta-synthase vs. Ensembl Celegans
Match: cbs-1 (Cystathionine Beta-Synthase [Source:UniProtKB/TrEMBL;Acc:G5EFH8]) HSP 1 Score: 375.555 bits (963), Expect = 1.549e-121 Identity = 201/361 (55.68%), Postives = 256/361 (70.91%), Query Frame = 3
Query: 135 SKCTFKLDSDPATSPHSKKEIH------DKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGK---IKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSC-DNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMD 1187
+K + DP T S E+ ++P ++D +L IG TPLVKL I K + C + VKCEY+N GGS KDRI+ RM+E AE +GK + PG TLIEPTSGNTGIGL+LA+AV+GYKCII MP+KMS EK + +LG+ I+RTP A +DSP S+I VA RLK EI ++ +L+QY NP NPLAHY+ TAEEI+ D ID+VV++AGTGGT+ G++RKI ++ P VVGVDP GSILA P ++ + FYEVEGIGYDF+P LD S +D W K DK+SF MAR LIR EG+LCGGSSG AV+ A++ K NLP A VVV+LPD +RNY+TKFL DDWM +R+F+D
Sbjct: 346 TKLAGEWTQDPETKSWSHSEVEFNKFNPERPLVLDTVLDAIGKTPLVKLQHIPKAHGVKCNVYVKCEYMNAGGSTKDRIAKRMVEIAEKTGKPGKLVPGVTLIEPTSGNTGIGLSLASAVRGYKCIITMPKKMSKEKSIAMASLGSTIIRTPNEAGFDSPHSHIGVALRLKSEIQDAVVLDQYCNPGNPLAHYEETAEEIIYDMGDKHIDLVVLTAGTGGTVTGISRKIHERIPTAKVVGVDPHGSILAGPA---ETDIDFYEVEGIGYDFLPGTLDTSAIDYWAKSHDKESFLMARELIRSEGILCGGSSGCAVHYALEECKSLNLPAEANVVVLLPDGIRNYITKFLDDDWMNERHFLD 703 HSP 2 Score: 97.4413 bits (241), Expect = 6.176e-21 Identity = 104/313 (33.23%), Postives = 155/313 (49.52%), Query Frame = 3
Query: 246 TPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVD-VLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDN----IIDMVVISAGTGGTLAGVARKIKQKCPKCL-VVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWM 1166
TPLV L K+ ++ +I VK EYLN GS++DR + + + AE G ++ GD + G+ I A AAVKG K I P K + VD VL LG + V P E+ + +Q+ S LN++T + +A+ TA EI + +N + VVI TG AG+A K + VVGV + K ++ +G D +L V+K +V + ++++ R LI EG++ G SSGAAV A++ AK+ LP + +VVVL D +RNY+ FL DDW+
Sbjct: 30 TPLVPLKKLKVEHQLQSDIYVKLEYLNIAGSLEDRTADKAFQFAEEIGVVR-GDEVFVTAGGSAAISYATVAAVKGIKLTIYAP-KGEFDLVDTVLHTLGVKTVELPFGT---FAEARVQTDEAAQQKGVFS--LNKFTTNAAFVANLQKTALEIEKAVNNKSIGKVGAVVIPLNTGAAAAGIAAYYKGIGEHGVRVVGV-----------TCKKDTIP-----EMGLDLKNDLLQEYNVEK-REVEEDEAYSFTRHLIGTEGIMAGPSSGAAVLEAIKLAKE--LPAGSTIVVVLMDGIRNYLRHFLDDDWI 316
BLAST of Cystathionine beta-synthase vs. Ensembl Celegans
Match: cbs-2 (Cystathionine Beta-Synthase [Source:UniProtKB/TrEMBL;Acc:Q9N4K2]) HSP 1 Score: 359.377 bits (921), Expect = 8.038e-116 Identity = 198/353 (56.09%), Postives = 248/353 (70.25%), Query Frame = 3
Query: 153 LDSDP----ATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGK---IKPG-DTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSC-DNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFM 1184
LD DP S K ++P ++D++L IG TPLVKL + K + C + VKCE+LN GGS KDRI+ +M+E AE +GK + PG TLIEPTSGNTGIGL+L AAV+GYKC+I MPEKMS EK L LG+ IVRTP A+++SP S+I VA RLK EIP + IL+QY NP NPLAHY+ TAEEIL D ID+VV+ AGTGGT+ G++RKI ++ P +VVGVDP GSIL P + + FYEVEGIGYDF+P LD VD W K DK+SF MAR +IR EG+LCGGSSG AV+ A++ + +LP+ A VVV+LPD +RNY+TKFL DDWM R F+
Sbjct: 312 LDYDPTKMVGEWKSSSKFRPERPLVLDSVLDAIGKTPLVKLQHVPKAHGVRCNVYVKCEFLNAGGSTKDRIAKKMVEIAEKTGKPGALTPGATTLIEPTSGNTGIGLSLVAAVRGYKCLITMPEKMSKEKSTTLSVLGSTIVRTPNEAAFNSPSSHIGVALRLKHEIPGAVILDQYCNPGNPLAHYEETAEEILWDMGDRKIDLVVLGAGTGGTITGISRKIHERRPNAIVVGVDPNGSILTGPTT--GPAPDFYEVEGIGYDFIPGTLDEKSVDSWLKSDDKESFLMAREIIRTEGILCGGSSGCAVHYALEQCRKLDLPEDANVVVLLPDGIRNYLTKFLDDDWMKARGFL 662 HSP 2 Score: 55.8398 bits (133), Expect = 7.129e-8 Identity = 50/163 (30.67%), Postives = 75/163 (46.01%), Query Frame = 3
Query: 228 LLDIG---LTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEI 707
+LD G T LV L K+ ++ +I VK EYLN GS++DR + R E S I+ GD + G++ + A AAVKG + P + +L LG +IV P S ++ +A R + L+ + LA+ +GTA EI
Sbjct: 12 ILDAGSHRATQLVPLKKLKAEFQLKSDIYVKLEYLNISGSLEDRAAHRAF---EMSNGIQRGDEVYVTAGGSSAVSYATVAAVKGVRLTAHAPPGAFDQVRTILSTLGTKIVELPVSNFREARLQADLLAKRR-----GVYNLDGICEKAAFLANLEGTAPEI 166
BLAST of Cystathionine beta-synthase vs. Ensembl Celegans
Match: cysl-2 (Bifunctional L-3-cyanoalanine synthase/cysteine synthase [Source:UniProtKB/Swiss-Prot;Acc:O45679]) HSP 1 Score: 207.223 bits (526), Expect = 1.702e-61 Identity = 119/270 (44.07%), Postives = 163/270 (60.37%), Query Frame = 3
Query: 237 IGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDT-LIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRT-PTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSG 1040
IG TPL+KLNKIGK + I VK EY+NP SVKDRI+ MI+ AE +G I PG T LIEPTSGN GI LA ++GYK I+ MP MSIE+ +L+A GAE++ T P +A + + A L+ IPN++ILNQ+ NP+NP AHY T EI +D+V G+GGT GV R +K+K P V V+PF S + IN + ++++G+G +P +LD + + +V D+ MA++L EE +L G SSG
Sbjct: 14 IGNTPLLKLNKIGK--DLGASIAVKVEYMNPACSVKDRIAFNMIDTAEKAGLITPGKTVLIEPTSGNMGIALAYCGKLRGYKVILTMPASMSIERRCLLKAYGAEVILTDPATAV----KGAVQRAEELRDVIPNAYILNQFGNPANPEAHYKTTGPEIWRQTQGKVDIVCFGVGSGGTCTGVGRFLKEKNPSVQVFPVEPFESSV-----INGLPHSPHKIQGMGTGMIPDILDLTLFSEALRVHSDDAIAMAKKLADEESILGGISSG 272
BLAST of Cystathionine beta-synthase vs. Ensembl Celegans
Match: cysl-2 (Bifunctional L-3-cyanoalanine synthase/cysteine synthase [Source:UniProtKB/Swiss-Prot;Acc:O45679]) HSP 1 Score: 207.223 bits (526), Expect = 1.702e-61 Identity = 119/270 (44.07%), Postives = 163/270 (60.37%), Query Frame = 3
Query: 237 IGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDT-LIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRT-PTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSG 1040
IG TPL+KLNKIGK + I VK EY+NP SVKDRI+ MI+ AE +G I PG T LIEPTSGN GI LA ++GYK I+ MP MSIE+ +L+A GAE++ T P +A + + A L+ IPN++ILNQ+ NP+NP AHY T EI +D+V G+GGT GV R +K+K P V V+PF S + IN + ++++G+G +P +LD + + +V D+ MA++L EE +L G SSG
Sbjct: 14 IGNTPLLKLNKIGK--DLGASIAVKVEYMNPACSVKDRIAFNMIDTAEKAGLITPGKTVLIEPTSGNMGIALAYCGKLRGYKVILTMPASMSIERRCLLKAYGAEVILTDPATAV----KGAVQRAEELRDVIPNAYILNQFGNPANPEAHYKTTGPEIWRQTQGKVDIVCFGVGSGGTCTGVGRFLKEKNPSVQVFPVEPFESSV-----INGLPHSPHKIQGMGTGMIPDILDLTLFSEALRVHSDDAIAMAKKLADEESILGGISSG 272
BLAST of Cystathionine beta-synthase vs. Ensembl Celegans
Match: cysl-1 (Cysteine synthase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q93244]) HSP 1 Score: 192.586 bits (488), Expect = 6.844e-56 Identity = 135/325 (41.54%), Postives = 184/325 (56.62%), Query Frame = 3
Query: 195 IHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPG-DTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSAR--VVVVLPDSVRNYMTKFLSDD 1160
+ D+ I +N IG TP+V +NK+ K + + VK EY+NP GSVKDRI M+ AE G + PG TLIEPTSGNTGI LA AA KGY+CI+ MP MS E+ +L+A G+E+V T + + I +A++LK+ IP S IL Q+ NP+NPL HY T EI +D VV GTGGT+ GV R ++++ P V V+P S + ++ ++++GIG F P VLD + ++ ++ MA+RL EEGLL G SSGA V AA+Q A P+ A +V LP YMT L D
Sbjct: 1 MADRNSIGENAAALIGNTPMVYINKLTK--GLPGTVAVKIEYMNPAGSVKDRIGAAMLAAAEKDGTVIPGVTTLIEPTSGNTGIALAFVAAAKGYRCIVTMPASMSGERRTLLKAYGSEVVLTDPAKGM---KGAIDMANQLKENIPGSIILAQFDNPNNPLVHYQTTGPEIWRQTKGTVDAVVFGVGTGGTITGVGRYLQEQNPGVRVFAVEPEESAI-----LSGRPAGPHKIQGIGAGFAPAVLDTKIYEDVIRIHSDEAIVMAQRLSYEEGLLGGISSGANVAAALQLAAR---PEMAGKLIVTCLPSCGERYMTSPLYTD 312
BLAST of Cystathionine beta-synthase vs. Ensembl Fly
Match: Cbs (gene:FBgn0031148 transcript:FBtr0077244) HSP 1 Score: 469.929 bits (1208), Expect = 1.227e-160 Identity = 261/519 (50.29%), Postives = 353/519 (68.02%), Query Frame = 3
Query: 81 PIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNA-PMTVQPSVTVEQTLELLKKEGFDQVPVV-ESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P P + F +PG SKC + L + SPH + I + +I NIL IG TPLVKLN I + I CE+ KCE+LNPGGSVKDRI RM++DAE G +KPG T+IEPTSGNTGIGLA+A AVKGYKCIIVMPEKMS EKV LR LGA+I+RTPT A+YDSPE I VA +L++E PNS +L+QY N NPLAHYDGTA EIL DN +DM+V+SAGT GT++G+ RKIK++ P C +VGVDP+GSILA+P +NK+ V FYEVEGIGYDF PTV D + VD W K+GD D F M+RRL EEGLLCGGSSG A++AA++ A+ L + R VV+LPD +RNYMTKF+SD+WM RNF + P+ N+ + + I+ L L A P+ ++ TV + + L+KK DQ+PVV + G ++G+ +++ ++ +DP KA+ K ++N + + +L+R+L++D VL++ + P G ELK + T++D+ +++
Sbjct: 2 PQPKPYERPADFIDPGKPSKCKWHLGT-AEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHAR--KLKKGQRCVVILPDGIRNYMTKFVSDNWMEARNFKE-PV----NEHGHWWWSLAIAELELPAPPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLILGK----NPAGKVELK----ALATKLDVTTFI 504
BLAST of Cystathionine beta-synthase vs. Ensembl Fly
Match: Cbs (gene:FBgn0031148 transcript:FBtr0077245) HSP 1 Score: 469.929 bits (1208), Expect = 1.227e-160 Identity = 261/519 (50.29%), Postives = 353/519 (68.02%), Query Frame = 3
Query: 81 PIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNA-PMTVQPSVTVEQTLELLKKEGFDQVPVV-ESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P P + F +PG SKC + L + SPH + I + +I NIL IG TPLVKLN I + I CE+ KCE+LNPGGSVKDRI RM++DAE G +KPG T+IEPTSGNTGIGLA+A AVKGYKCIIVMPEKMS EKV LR LGA+I+RTPT A+YDSPE I VA +L++E PNS +L+QY N NPLAHYDGTA EIL DN +DM+V+SAGT GT++G+ RKIK++ P C +VGVDP+GSILA+P +NK+ V FYEVEGIGYDF PTV D + VD W K+GD D F M+RRL EEGLLCGGSSG A++AA++ A+ L + R VV+LPD +RNYMTKF+SD+WM RNF + P+ N+ + + I+ L L A P+ ++ TV + + L+KK DQ+PVV + G ++G+ +++ ++ +DP KA+ K ++N + + +L+R+L++D VL++ + P G ELK + T++D+ +++
Sbjct: 2 PQPKPYERPADFIDPGKPSKCKWHLGT-AEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHAR--KLKKGQRCVVILPDGIRNYMTKFVSDNWMEARNFKE-PV----NEHGHWWWSLAIAELELPAPPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLILGK----NPAGKVELK----ALATKLDVTTFI 504
BLAST of Cystathionine beta-synthase vs. Ensembl Fly
Match: Cbs (gene:FBgn0031148 transcript:FBtr0340437) HSP 1 Score: 469.929 bits (1208), Expect = 1.227e-160 Identity = 261/519 (50.29%), Postives = 353/519 (68.02%), Query Frame = 3
Query: 81 PIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNA-PMTVQPSVTVEQTLELLKKEGFDQVPVV-ESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P P + F +PG SKC + L + SPH + I + +I NIL IG TPLVKLN I + I CE+ KCE+LNPGGSVKDRI RM++DAE G +KPG T+IEPTSGNTGIGLA+A AVKGYKCIIVMPEKMS EKV LR LGA+I+RTPT A+YDSPE I VA +L++E PNS +L+QY N NPLAHYDGTA EIL DN +DM+V+SAGT GT++G+ RKIK++ P C +VGVDP+GSILA+P +NK+ V FYEVEGIGYDF PTV D + VD W K+GD D F M+RRL EEGLLCGGSSG A++AA++ A+ L + R VV+LPD +RNYMTKF+SD+WM RNF + P+ N+ + + I+ L L A P+ ++ TV + + L+KK DQ+PVV + G ++G+ +++ ++ +DP KA+ K ++N + + +L+R+L++D VL++ + P G ELK + T++D+ +++
Sbjct: 2 PQPKPYERPADFIDPGKPSKCKWHLGT-AEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHAR--KLKKGQRCVVILPDGIRNYMTKFVSDNWMEARNFKE-PV----NEHGHWWWSLAIAELELPAPPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLILGK----NPAGKVELK----ALATKLDVTTFI 504
BLAST of Cystathionine beta-synthase vs. Ensembl Zebrafish
Match: cbsa (cystathionine beta-synthase a [Source:ZFIN;Acc:ZDB-GENE-050417-367]) HSP 1 Score: 580.096 bits (1494), Expect = 0.000e+0 Identity = 299/514 (58.17%), Postives = 385/514 (74.90%), Query Frame = 3
Query: 111 QFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFM--DKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIESTK 1646
++ P + S+CT+K SPH+ I+ NIL IG TPLV +NKI KI + CE+L KCE+ N GGSVKDRISLRM+EDAE G + PGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V AGTGGT+ G+ARK+K+KCP +V VDP GSILA+P+ +N++ YEVEGIGYDF+PTVLDRS VDKWYK D++SF MAR LIR+EGLLCGGSSG A+ AAV+ AK+ L + R VV+LPDS+RNYM+KFLSD WM+ + F+ + M N+ + K+ SLNL+AP+TV P+VT ++T+++LK +GFDQ PVV +G I+GM T+G +++ ++ + +DPVSK +YK FK++ L + +LSR+L+ DHF LVVH+Q Q G+ K+M++G+VT IDL++++ K
Sbjct: 53 KWIRPDLPSRCTWKPGMSHENSPHTYFPRTKAECILPNILGKIGDTPLVNINKISKIFGLKCELLAKCEFFNAGGSVKDRISLRMVEDAEREGILNPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNSHILDQYRNPSNPLAHYDTTAEEILEQCDGKVDMLVAGAGTGGTITGIARKLKEKCPNIKIVAVDPEGSILAEPDELNRTDKNQYEVEGIGYDFIPTVLDRSLVDKWYKSKDEESFAMARMLIRDEGLLCGGSSGTAMAAAVKFAKE--LKEGQRCVVILPDSIRNYMSKFLSDKWMFQKGFLRVEDIMVNKP-----WWWNLKLQSLNLSAPLTVLPTVTCQKTIKILKDKGFDQAPVVNEAGLILGMVTLGNMLASVLAGKVKPSDPVSKVLYKQFKQIRLTDNMGKLSRILETDHFALVVHEQIQYLTDGSSSQKQMVFGVVTAIDLLNFVTAREK 559
BLAST of Cystathionine beta-synthase vs. Ensembl Zebrafish
Match: cbsb (cystathionine beta-synthase b [Source:ZFIN;Acc:ZDB-GENE-021030-3]) HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0 Identity = 295/514 (57.39%), Postives = 386/514 (75.10%), Query Frame = 3
Query: 111 QFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFM-------DKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
++ P + S+CT+KL SPH+ + I+ NIL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRMIEDAE G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPN+HIL+QY NPSNPLAHYD TAEEIL C IDM+V AGTGGT+ G+ARK+K+KCP ++GVDP GSILA+P+ +NK+ T YEVEGIGYDF+PTVLDRS VD WYK D++SF M+R LIREEGLLCGGSSG A+ AAV AK+ L + R VV+LPDS+RNYM+KFLSD WM+++ FM +KP + + L L+AP+TV P V++++T+++LK++ FDQ PVV+ +G I+GM T+G +++ ++ + +DP+SK +YK FK+V L + +LSR+L+ DHF LVVH+Q Q G+ ++++M++G+VT IDL++Y+
Sbjct: 77 KWIRPDLPSRCTWKLGDLNMESPHNHYQRTKTSGILPNILSKIGETPMVRMNKIPKAFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNAHILDQYRNPSNPLAHYDTTAEEILEQCGGKIDMLVAGAGTGGTITGIARKLKEKCPDIKIIGVDPEGSILAEPDELNKTDKTQYEVEGIGYDFIPTVLDRSVVDNWYKSNDEESFAMSRMLIREEGLLCGGSSGTAMSAAVNVAKE--LKEGQRCVVILPDSIRNYMSKFLSDKWMFEKGFMSEEDLVVNKPWW----------WNLTLQELRLSAPLTVLPLVSIKKTIQILKEKAFDQAPVVDEAGHILGMVTLGNMLASVLAGKVRPSDPISKVLYKQFKQVRLTDNLGKLSRILETDHFALVVHEQIQYMSDGSPKMRQMVFGVVTAIDLLNYV 578
BLAST of Cystathionine beta-synthase vs. Ensembl Zebrafish
Match: cbsb (cystathionine beta-synthase b [Source:ZFIN;Acc:ZDB-GENE-021030-3]) HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0 Identity = 295/514 (57.39%), Postives = 386/514 (75.10%), Query Frame = 3
Query: 111 QFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFM-------DKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
++ P + S+CT+KL SPH+ + I+ NIL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRMIEDAE G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPN+HIL+QY NPSNPLAHYD TAEEIL C IDM+V AGTGGT+ G+ARK+K+KCP ++GVDP GSILA+P+ +NK+ T YEVEGIGYDF+PTVLDRS VD WYK D++SF M+R LIREEGLLCGGSSG A+ AAV AK+ L + R VV+LPDS+RNYM+KFLSD WM+++ FM +KP + + L L+AP+TV P V++++T+++LK++ FDQ PVV+ +G I+GM T+G +++ ++ + +DP+SK +YK FK+V L + +LSR+L+ DHF LVVH+Q Q G+ ++++M++G+VT IDL++Y+
Sbjct: 77 KWIRPDLPSRCTWKLGDLNMESPHNHYQRTKTSGILPNILSKIGETPMVRMNKIPKAFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNAHILDQYRNPSNPLAHYDTTAEEILEQCGGKIDMLVAGAGTGGTITGIARKLKEKCPDIKIIGVDPEGSILAEPDELNKTDKTQYEVEGIGYDFIPTVLDRSVVDNWYKSNDEESFAMSRMLIREEGLLCGGSSGTAMSAAVNVAKE--LKEGQRCVVILPDSIRNYMSKFLSDKWMFEKGFMSEEDLVVNKPWW----------WNLTLQELRLSAPLTVLPLVSIKKTIQILKEKAFDQAPVVDEAGHILGMVTLGNMLASVLAGKVRPSDPISKVLYKQFKQVRLTDNLGKLSRILETDHFALVVHEQIQYMSDGSPKMRQMVFGVVTAIDLLNYV 578
BLAST of Cystathionine beta-synthase vs. Ensembl Zebrafish
Match: cbsa (cystathionine beta-synthase a [Source:ZFIN;Acc:ZDB-GENE-050417-367]) HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0 Identity = 299/514 (58.17%), Postives = 385/514 (74.90%), Query Frame = 3
Query: 111 QFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFM--DKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIESTK 1646
++ P + S+CT+K SPH+ I+ NIL IG TPLV +NKI KI + CE+L KCE+ N GGSVKDRISLRM+EDAE G + PGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V AGTGGT+ G+ARK+K+KCP +V VDP GSILA+P+ +N++ YEVEGIGYDF+PTVLDRS VDKWYK D++SF MAR LIR+EGLLCGGSSG A+ AAV+ AK+ L + R VV+LPDS+RNYM+KFLSD WM+ + F+ + M N+ + K+ SLNL+AP+TV P+VT ++T+++LK +GFDQ PVV +G I+GM T+G +++ ++ + +DPVSK +YK FK++ L + +LSR+L+ DHF LVVH+Q Q G+ K+M++G+VT IDL++++ K
Sbjct: 53 KWIRPDLPSRCTWKPGMSHENSPHTYFPRTKAECILPNILGKIGDTPLVHINKISKIFGLKCELLAKCEFFNAGGSVKDRISLRMVEDAEREGILNPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNSHILDQYRNPSNPLAHYDTTAEEILEQCDGKVDMLVAGAGTGGTITGIARKLKEKCPNIKIVAVDPEGSILAEPDELNRTDKNQYEVEGIGYDFIPTVLDRSLVDKWYKSKDEESFAMARMLIRDEGLLCGGSSGTAMAAAVKFAKE--LKEGQRCVVILPDSIRNYMSKFLSDKWMFQKGFLRVEDIMVNKP-----WWWNLKLQSLNLSAPLTVLPTVTCQKTIKILKDKGFDQAPVVNEAGLILGMVTLGNMLASVLAGKVKPSDPVSKVLYKQFKQIRLTDNMGKLSRILETDHFALVVHEQIQYLTDGSSSQKQMVFGVVTAIDLLNFVTAREK 559
BLAST of Cystathionine beta-synthase vs. Ensembl Zebrafish
Match: cbsa (cystathionine beta-synthase a [Source:ZFIN;Acc:ZDB-GENE-050417-367]) HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0 Identity = 299/514 (58.17%), Postives = 385/514 (74.90%), Query Frame = 3
Query: 111 QFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFM--DKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIESTK 1646
++ P + S+CT+K SPH+ I+ NIL IG TPLV +NKI KI + CE+L KCE+ N GGSVKDRISLRM+EDAE G + PGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V AGTGGT+ G+ARK+K+KCP +V VDP GSILA+P+ +N++ YEVEGIGYDF+PTVLDRS VDKWYK D++SF MAR LIR+EGLLCGGSSG A+ AAV+ AK+ L + R VV+LPDS+RNYM+KFLSD WM+ + F+ + M N+ + K+ SLNL+AP+TV P+VT ++T+++LK +GFDQ PVV +G I+GM T+G +++ ++ + +DPVSK +YK FK++ L + +LSR+L+ DHF LVVH+Q Q G+ K+M++G+VT IDL++++ K
Sbjct: 53 KWIRPDLPSRCTWKPGMSHENSPHTYFPRTKAECILPNILGKIGDTPLVHINKISKIFGLKCELLAKCEFFNAGGSVKDRISLRMVEDAEREGILNPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNSHILDQYRNPSNPLAHYDTTAEEILEQCDGKVDMLVAGAGTGGTITGIARKLKEKCPNIKIVAVDPEGSILAEPDELNRTDKNQYEVEGIGYDFIPTVLDRSLVDKWYKSKDEESFAMARMLIRDEGLLCGGSSGTAMAAAVKFAKE--LKEGQRCVVILPDSIRNYMSKFLSDKWMFQKGFLRVEDIMVNKP-----WWWNLKLQSLNLSAPLTVLPTVTCQKTIKILKDKGFDQAPVVNEAGLILGMVTLGNMLASVLAGKVKPSDPVSKVLYKQFKQIRLTDNMGKLSRILETDHFALVVHEQIQYLTDGSSSQKQMVFGVVTAIDLLNFVTAREK 559
BLAST of Cystathionine beta-synthase vs. Ensembl Xenopus
Match: nipal3 (NIPA-like domain containing 3 [Source:Xenbase;Acc:XB-GENE-946030]) HSP 1 Score: 51.6026 bits (122), Expect = 3.090e-6 Identity = 50/183 (27.32%), Postives = 81/183 (44.26%), Query Frame = 3
Query: 297 EILVKCEYLNPGGSVKDRISLRMI----EDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVR-TPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVD 830
E+ +K EYL GSVK+R L ++ +D + G +I T N + +A A+ ++M S+ +V + R GA ++ PT+ S A RL QE N ++ + + + LA EI N+ ++ + G G LAG A +K PK V+GV+
Sbjct: 161 ELYLKKEYLQYTGSVKERGVLYLLTSLPQDQQRKG-------VIVATDSNFALAVAFHASELQIPVFVIMSAGTSLGRVRMCRDYGAMVILFGPTARDAQSH------ARRLAQE--NGYLYIEEEDSAGYLAGLGTVGLEIYEQVPNLDAVIFPAGGHCGLLAGSAAALKHLNPKITVIGVE 328
BLAST of Cystathionine beta-synthase vs. Ensembl Xenopus
Match: nipal3 (NIPA-like domain containing 3 [Source:Xenbase;Acc:XB-GENE-946030]) HSP 1 Score: 51.6026 bits (122), Expect = 3.490e-6 Identity = 50/183 (27.32%), Postives = 81/183 (44.26%), Query Frame = 3
Query: 297 EILVKCEYLNPGGSVKDRISLRMI----EDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVR-TPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVD 830
E+ +K EYL GSVK+R L ++ +D + G +I T N + +A A+ ++M S+ +V + R GA ++ PT+ S A RL QE N ++ + + + LA EI N+ ++ + G G LAG A +K PK V+GV+
Sbjct: 170 ELYLKKEYLQYTGSVKERGVLYLLTSLPQDQQRKG-------VIVATDSNFALAVAFHASELQIPVFVIMSAGTSLGRVRMCRDYGAMVILFGPTARDAQSH------ARRLAQE--NGYLYIEEEDSAGYLAGLGTVGLEIYEQVPNLDAVIFPAGGHCGLLAGSAAALKHLNPKITVIGVE 337
BLAST of Cystathionine beta-synthase vs. Ensembl Mouse
Match: Cbs (cystathionine beta-synthase [Source:MGI Symbol;Acc:MGI:88285]) HSP 1 Score: 608.601 bits (1568), Expect = 0.000e+0 Identity = 295/503 (58.65%), Postives = 383/503 (76.14%), Query Frame = 3
Query: 123 PGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P S+CT++L A SPH + PKI+ +IL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRMIEDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TAEEIL CD +DM+V SAGTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+DSF AR LI +EGLLCGGSSG+A+ AV+AA++ L + R VV+LPDSVRNYM+KFLSD WM + FM + ++ + + ++ L+L+AP+TV P+VT E T+ +L+++GFDQ PVV SG I+GM T+G ++S L+ + +D V K +YK FK ++L T+ LS +L++DHF LVVH+Q Q G ++M++G+VT IDL++++
Sbjct: 43 PDTPSRCTWQLGRAMADSPHYHTVLTKSPKILPDILRKIGNTPMVRINKISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGNLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKLDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDKWFKSNDEDSFAFARMLIAQEGLLCGGSSGSAMAVAVKAARE--LQEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMKEELSV----KRPWWWRLRVQELSLSAPLTVLPTVTCEDTIAILREKGFDQAPVVNESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGTLSHILEMDHFALVVHEQIQYCSNGMSSKQQMVFGVVTAIDLLNFV 539
BLAST of Cystathionine beta-synthase vs. Ensembl Mouse
Match: Cbs (cystathionine beta-synthase [Source:MGI Symbol;Acc:MGI:88285]) HSP 1 Score: 608.601 bits (1568), Expect = 0.000e+0 Identity = 295/503 (58.65%), Postives = 383/503 (76.14%), Query Frame = 3
Query: 123 PGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P S+CT++L A SPH + PKI+ +IL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRMIEDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TAEEIL CD +DM+V SAGTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+DSF AR LI +EGLLCGGSSG+A+ AV+AA++ L + R VV+LPDSVRNYM+KFLSD WM + FM + ++ + + ++ L+L+AP+TV P+VT E T+ +L+++GFDQ PVV SG I+GM T+G ++S L+ + +D V K +YK FK ++L T+ LS +L++DHF LVVH+Q Q G ++M++G+VT IDL++++
Sbjct: 43 PDTPSRCTWQLGRAMADSPHYHTVLTKSPKILPDILRKIGNTPMVRINKISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGNLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKLDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDKWFKSNDEDSFAFARMLIAQEGLLCGGSSGSAMAVAVKAARE--LQEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMKEELSV----KRPWWWRLRVQELSLSAPLTVLPTVTCEDTIAILREKGFDQAPVVNESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGTLSHILEMDHFALVVHEQIQYCSNGMSSKQQMVFGVVTAIDLLNFV 539
BLAST of Cystathionine beta-synthase vs. Ensembl Mouse
Match: Cbs (cystathionine beta-synthase [Source:MGI Symbol;Acc:MGI:88285]) HSP 1 Score: 599.742 bits (1545), Expect = 0.000e+0 Identity = 297/517 (57.45%), Postives = 385/517 (74.47%), Query Frame = 3
Query: 123 PGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQIT----------PT----GTEELKEMIYGIVTRIDLISYM 1631
P S+CT++L A SPH + PKI+ +IL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRMIEDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TAEEIL CD +DM+V SAGTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+DSF AR LI +EGLLCGGSSG+A+ AV+AA++ L + R VV+LPDSVRNYM+KFLSD WM + FM + ++ + + ++ L+L+AP+TV P+VT E T+ +L+++GFDQ PVV SG I+GM T+G ++S L+ + +D V K +YK FK ++L T+ LS +L++DHF LVVH+Q Q PT G ++M++G+VT IDL++++
Sbjct: 43 PDTPSRCTWQLGRAMADSPHYHTVLTKSPKILPDILRKIGNTPMVRINKISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGNLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKLDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDKWFKSNDEDSFAFARMLIAQEGLLCGGSSGSAMAVAVKAARE--LQEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMKEELSV----KRPWWWRLRVQELSLSAPLTVLPTVTCEDTIAILREKGFDQAPVVNESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGTLSHILEMDHFALVVHEQIQSRDQAWSGVVGGPTDCSNGMSSKQQMVFGVVTAIDLLNFV 553
BLAST of Cystathionine beta-synthase vs. Ensembl Mouse
Match: Cbs (cystathionine beta-synthase [Source:MGI Symbol;Acc:MGI:88285]) HSP 1 Score: 599.742 bits (1545), Expect = 0.000e+0 Identity = 297/517 (57.45%), Postives = 385/517 (74.47%), Query Frame = 3
Query: 123 PGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQIT----------PT----GTEELKEMIYGIVTRIDLISYM 1631
P S+CT++L A SPH + PKI+ +IL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRMIEDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TAEEIL CD +DM+V SAGTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+DSF AR LI +EGLLCGGSSG+A+ AV+AA++ L + R VV+LPDSVRNYM+KFLSD WM + FM + ++ + + ++ L+L+AP+TV P+VT E T+ +L+++GFDQ PVV SG I+GM T+G ++S L+ + +D V K +YK FK ++L T+ LS +L++DHF LVVH+Q Q PT G ++M++G+VT IDL++++
Sbjct: 43 PDTPSRCTWQLGRAMADSPHYHTVLTKSPKILPDILRKIGNTPMVRINKISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGNLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKLDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDKWFKSNDEDSFAFARMLIAQEGLLCGGSSGSAMAVAVKAARE--LQEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMKEELSV----KRPWWWRLRVQELSLSAPLTVLPTVTCEDTIAILREKGFDQAPVVNESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGTLSHILEMDHFALVVHEQIQSRDQAWSGVVGGPTDCSNGMSSKQQMVFGVVTAIDLLNFV 553
BLAST of Cystathionine beta-synthase vs. Ensembl Mouse
Match: Cbs (cystathionine beta-synthase [Source:MGI Symbol;Acc:MGI:88285]) HSP 1 Score: 377.096 bits (967), Expect = 4.234e-128 Identity = 175/234 (74.79%), Postives = 203/234 (86.75%), Query Frame = 3
Query: 303 LVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLI 1004
+ KCE+ N GGSVKDRISLRMIEDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TAEEIL CD +DM+V SAGTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+DSF AR LI
Sbjct: 18 VAKCEFFNAGGSVKDRISLRMIEDAERAGNLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKLDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDKWFKSNDEDSFAFARMLI 251
BLAST of Cystathionine beta-synthase vs. UniProt/SwissProt
Match: sp|P35520|CBS_HUMAN (Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2) HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0 Identity = 292/512 (57.03%), Postives = 384/512 (75.00%), Query Frame = 3
Query: 96 KSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
K PL + P S+CT++L + SPH PKI+ +IL IG TP+V++NKIGK + CE+L KCE+ N GGSVKDRISLRMIEDAE G +KPGDT+IEPTSGNTGIGLALAAAV+GY+CIIVMPEKMS EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TA+EIL CD +DM+V S GTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+++F AR LI +EGLLCGGS+G+ V AV+AA++ L + R VV+LPDSVRNYMTKFLSD WM + F+ + ++ + ++ L L+AP+TV P++T T+E+L+++GFDQ PVV+ +G I+GM T+G ++S L+ + +D V K IYK FK++ L T+ +LS +L++DHF LVVH+Q Q TG ++M++G+VT IDL++++
Sbjct: 39 KEPL--WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE--LQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKE---EDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFV 543
BLAST of Cystathionine beta-synthase vs. UniProt/SwissProt
Match: sp|P0DN79|CBSL_HUMAN (Cystathionine beta-synthase-like protein OS=Homo sapiens OX=9606 GN=CBSL PE=1 SV=1) HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0 Identity = 292/512 (57.03%), Postives = 384/512 (75.00%), Query Frame = 3
Query: 96 KSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
K PL + P S+CT++L + SPH PKI+ +IL IG TP+V++NKIGK + CE+L KCE+ N GGSVKDRISLRMIEDAE G +KPGDT+IEPTSGNTGIGLALAAAV+GY+CIIVMPEKMS EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TA+EIL CD +DM+V S GTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+++F AR LI +EGLLCGGS+G+ V AV+AA++ L + R VV+LPDSVRNYMTKFLSD WM + F+ + ++ + ++ L L+AP+TV P++T T+E+L+++GFDQ PVV+ +G I+GM T+G ++S L+ + +D V K IYK FK++ L T+ +LS +L++DHF LVVH+Q Q TG ++M++G+VT IDL++++
Sbjct: 39 KEPL--WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQE--LQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKE---EDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFV 543
BLAST of Cystathionine beta-synthase vs. UniProt/SwissProt
Match: sp|Q58H57|CBS_MACFA (Cystathionine beta-synthase OS=Macaca fascicularis OX=9541 GN=CBS PE=2 SV=3) HSP 1 Score: 600.897 bits (1548), Expect = 0.000e+0 Identity = 289/512 (56.45%), Postives = 385/512 (75.20%), Query Frame = 3
Query: 96 KSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
K PL + P S+CT++L + SPH PKI+ +IL IG TP++++NKIGK + CE+L KCE+ N GGSVKDRISLRMIEDAE +G +KPGDT+IEPTSGNTGIGLAL AAV+GY+CIIVMPEKMS EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TA+EIL CD +DM+V S GTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+++F AR LI +EGLLCGGS+G+ + AV+AA++ L + R VV+LPDSVRNYMTKFLSD WM + F+ + ++ + ++ L+L+AP+TV P+V+ E T+E+L+++GFDQ PVV+ +G I+GM T+G ++S L+ + +D V K IY FK++ L T+ +LS +L++DHF LVVH+Q Q TG ++M++G+VT IDL++++
Sbjct: 39 KEPL--WIRPDAPSRCTWQLGRPASESPHHHTVPEKSPKILPDILKKIGDTPMIRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGTLKPGDTIIEPTSGNTGIGLALTAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILRQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTMAVAVKAAQE--LQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKE---EDLMEKKPWWWHLRVQELSLSAPLTVLPTVSCEHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYTQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFV 543
BLAST of Cystathionine beta-synthase vs. UniProt/SwissProt
Match: sp|Q91WT9|CBS_MOUSE (Cystathionine beta-synthase OS=Mus musculus OX=10090 GN=Cbs PE=1 SV=3) HSP 1 Score: 599.742 bits (1545), Expect = 0.000e+0 Identity = 297/517 (57.45%), Postives = 385/517 (74.47%), Query Frame = 3
Query: 123 PGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQIT----------PT----GTEELKEMIYGIVTRIDLISYM 1631
P S+CT++L A SPH + PKI+ +IL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRMIEDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TAEEIL CD +DM+V SAGTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VDKW+K D+DSF AR LI +EGLLCGGSSG+A+ AV+AA++ L + R VV+LPDSVRNYM+KFLSD WM + FM + ++ + + ++ L+L+AP+TV P+VT E T+ +L+++GFDQ PVV SG I+GM T+G ++S L+ + +D V K +YK FK ++L T+ LS +L++DHF LVVH+Q Q PT G ++M++G+VT IDL++++
Sbjct: 43 PDTPSRCTWQLGRAMADSPHYHTVLTKSPKILPDILRKIGNTPMVRINKISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGNLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKLDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDKWFKSNDEDSFAFARMLIAQEGLLCGGSSGSAMAVAVKAARE--LQEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMKEELSV----KRPWWWRLRVQELSLSAPLTVLPTVTCEDTIAILREKGFDQAPVVNESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGTLSHILEMDHFALVVHEQIQSRDQAWSGVVGGPTDCSNGMSSKQQMVFGVVTAIDLLNFV 553
BLAST of Cystathionine beta-synthase vs. UniProt/SwissProt
Match: sp|P32232|CBS_RAT (Cystathionine beta-synthase OS=Rattus norvegicus OX=10116 GN=Cbs PE=1 SV=3) HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0 Identity = 295/518 (56.95%), Postives = 383/518 (73.94%), Query Frame = 3
Query: 120 NPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQIT----------PT----GTEELKEMIYGIVTRIDLISYM 1631
+P S+CT++L A SPH PKI+ +IL IG TP+V++N+I K + CE+L KCE+ N GGSVKDRISLRMIEDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPT+A +DSPES++ VA RLK EIPNSHIL+QY N SNPLAHYD TAEEIL CD +DM+V SAGTGGT+ G+ARK+K+KCP C ++GVDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VD+W+K D DSF AR LI +EGLLCGGSSG+A+ AV+AA++ L + R VV+LPDSVRNYM+KFLSD WM + FM + ++ + + ++ L+L+AP+TV P+VT E T+ +L+++GFDQ PVV SG I+GM T+G ++S L+ + +D V K +YK FK ++L T+ LS +L++DHF LVVH+Q Q PT G + M++G+VT IDL++++
Sbjct: 42 SPDTPSRCTWQLGRPMADSPHYHTVPTKSPKILPDILRKIGNTPMVRINRISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGTLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKVDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDRWFKSNDDDSFAFARMLISQEGLLCGGSSGSAMAVAVKAAQE--LKEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMKEELSV----KRPWWWHLRVQELSLSAPLTVLPTVTCEHTIAILREKGFDQAPVVNESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGMLSHILEMDHFALVVHEQIQSRDQAWSGVVGGPTDRNNGVSSKQLMVFGVVTAIDLLNFV 553
BLAST of Cystathionine beta-synthase vs. TrEMBL
Match: A0A0B7B823 (Cystathionine beta-synthase OS=Arion vulgaris OX=1028688 GN=ORF168729 PE=3 SV=1) HSP 1 Score: 666.381 bits (1718), Expect = 0.000e+0 Identity = 322/514 (62.65%), Postives = 405/514 (78.79%), Query Frame = 3
Query: 90 SIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
+I Q+ P + SKCTF+L++ SPH +PKI+ +IL +IG TPLV++NKI E I CEIL KCE+ N GGSVKDRI RM+EDAE +G+IKPGD LIEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA++DSPES+I VAHRL E+PNSHIL+QY N SNP+AH+DGTA+EIL +CD +DM+V +AGTGGT+AG++RKIK CP C ++GVDP GSILA+PES+NK+ V+FYEVEGIGYDFVPTVL R +VDKWYK DK SF M+RRLIREEGLLCGGSSG+A++ AVQA KDF L + R VV+LPDSVRNYM+KFLSDDWM R+F++ + + +S+LNL AP+TV P+V ++ TL+LL KEGFDQVPVV+ +GCI+GM TVG +M+ ++KK + +D VS +YK FK++ +++++ QLSR+LD DHFVLVVH QRQ G E K+MI+GI TRIDL++++
Sbjct: 12 AIDGQFRQWKRPDLASKCTFQLNTPIEQSPHRHVTKSSRPKILPSILHNIGDTPLVRINKITVKEGIECEILAKCEFFNAGGSVKDRIGYRMVEDAEIAGQIKPGDVLIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSAAFDSPESHIGVAHRLMGEVPNSHILDQYRNASNPVAHFDGTAQEILDACDGKVDMIVATAGTGGTIAGISRKIKMHCPDCKIIGVDPEGSILAEPESLNKNEVSFYEVEGIGYDFVPTVLSREYVDKWYKSMDKPSFLMSRRLIREEGLLCGGSSGSAMHCAVQAVKDFGLKKGQRCVVILPDSVRNYMSKFLSDDWMSQRDFLE--LERLMEPSKEWWWTLNVSALNLLAPLTVMPTVLIQDTLDLLNKEGFDQVPVVDETGCILGMVTVGNMMAKIIKKKVRRSDQVSTVMYKQFKQIRMDTSLGQLSRMLDTDHFVLVVHNQRQYGVDGKVENKQMIFGIATRIDLLNFI 523
BLAST of Cystathionine beta-synthase vs. TrEMBL
Match: V4A5D0 (Cystathionine beta-synthase OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_219173 PE=3 SV=1) HSP 1 Score: 645.195 bits (1663), Expect = 0.000e+0 Identity = 322/514 (62.65%), Postives = 408/514 (79.38%), Query Frame = 3
Query: 96 KSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIE 1637
+SP + P + SKCT+ D SPH + KP IM NIL +IG TPLV++N+I + E + CE+L KCE+ N GGSVKDRI LRMIEDAEA G +KPGD LIEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVD+LRALGAEIVRTPTSA++DSPES+I VA RL +EIPNSHIL+QY NPSNPLAHYD TAEEIL +CDN +DM+V++AGTGGTL G+ARKIK+KCP C ++GVDP GSI+A+PE +NKS +FYEVEGIGYDF+PTV DRS VDKWYK DKDSF MARRLI+EEGLLCGGS G+AVY A++A KDF L + R VVLPDS+RNYMTK LSDDW+ R+F++ + + + K+S+L+L AP+TV P+VTV++TL++L KEGFDQVP+++ +G ++GM T+G +MS ++K + +DPV+K +YK FK+++L++T+ QLSRLLD DH+VLVVHQQRQ T K+MI+GI TRIDL++++ +
Sbjct: 9 ESPYRIWKRPDLPSKCTYTPDKSIDQSPHRHIKQKQKPAIMPNILYNIGNTPLVRINRITEKEGVKCELLAKCEFFNSGGSVKDRIGLRMIEDAEAQGVLKPGDVLIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDILRALGAEIVRTPTSAAFDSPESHIGVAKRLMEEIPNSHILDQYRNPSNPLAHYDCTAEEILAACDNKLDMMVLTAGTGGTLTGIARKIKEKCPSCKIIGVDPAGSIIAEPEELNKSDTSFYEVEGIGYDFIPTVCDRSPVDKWYKSVDKDSFIMARRLIKEEGLLCGGSCGSAVYCAIKAIKDFGLKEGQRCAVVLPDSIRNYMTKHLSDDWLSQRHFLE--LKKDVDPSKAWWWNLKVSALSLRAPLTVTPTVTVQETLDILNKEGFDQVPIMDDNGDVLGMVTIGNLMSQIVKHKVKRSDPVNKVMYKQFKQISLDTTLSQLSRLLDTDHYVLVVHQQRQYTGPSVISKKQMIFGIATRIDLLNFITQ 520
BLAST of Cystathionine beta-synthase vs. TrEMBL
Match: A0A1I8GKK3 (Cystathionine beta-synthase OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 643.269 bits (1658), Expect = 0.000e+0 Identity = 329/513 (64.13%), Postives = 406/513 (79.14%), Query Frame = 3
Query: 111 QFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSN-----DRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMI 1634
Q PN S+C FK+D + SPH+ ++ +PKI+ NIL IG TPLV+LN I K E ISCEIL KCE+ N GGSVKDRI LRMIEDAE SG++KPGD LIEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS EKVDVLRALGAEIVRTPT+AS+DS ES+I VA RL QE+PN+ IL+QYTNPSNPLAHYDGTAEE+L +C+N IDMVV AGTGGT+AG+ARKIKQ+CP CL+VGVDP+GSILAQPES+N++SVT Y+VEGIGYDFVPTVLDRS VD W+K D +SF+MARRLIR EGLLCGGSSG+AV++A+ A + + L RVVV+LPDSVRNYMTKFLS+DW+ +R + P + +N D + ++ SL+L AP++V P V+V++ LELL +EGFDQ+PVV + G I+GMAT+G IMS ++K TL TDPVS A+Y F KV + + +SR LD DHF+LVV+QQRQ E +KE+I+GI+TRIDL++Y++
Sbjct: 2891 QLPN--HQSQCKFKIDLPISESPHNHVKLTPEPKILSNILQHIGNTPLVRLNSIPKAENISCEILAKCEFFNAGGSVKDRIGLRMIEDAEKSGRLKPGDVLIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSKEKVDVLRALGAEIVRTPTAASFDSAESHIGVAKRLLQEMPNALILDQYTNPSNPLAHYDGTAEELLEACNNQIDMVVAGAGTGGTIAGLARKIKQRCPNCLIVGVDPYGSILAQPESLNETSVTQYDVEGIGYDFVPTVLDRSLVDCWFKSSDAESFDMARRLIRHEGLLCGGSSGSAVHSALAAIRHYKLGPGKRVVVMLPDSVRNYMTKFLSEDWLIERGY--APTQDFANGVGESDSDTRWKSVRVGSLDLKAPLSVLPDVSVKEALELLNREGFDQLPVVHADGKIVGMATLGFIMSHIIKGTLKPTDPVSNAVYHKFTKVTPDCPLGVISRHLDSDHFILVVNQQRQYLGDRKESVKEVIFGILTRIDLLNYLL 3399
BLAST of Cystathionine beta-synthase vs. TrEMBL
Match: A0A267F346 (Cystathionine beta-synthase (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000058g2 PE=3 SV=1) HSP 1 Score: 642.884 bits (1657), Expect = 0.000e+0 Identity = 316/506 (62.45%), Postives = 388/506 (76.68%), Query Frame = 3
Query: 123 PGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVE-SSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIE 1637
P S+CTF++D SPH ++ ++PKI+ +IL IG TPLV++N I K E I CEILVKCE+ N GGSVKDRI LRMIEDAE SG++KPGD LIEPTSGNTGIGLALAAAVKGY+C IVMPEKMS EKVDVLRALGA+IVRTPT+ASYDS ES+I VA +L + NSHIL+QYTNPSNP+AH+DGTAEEIL +C +DMVV+ AGTGGTL GVARK+KQ+CP CL++GVDP GSILAQP+ +N + VT Y+VEGIGYDFVPTVLDRS VD+WYK D DS MARRLIR EGLLCGGSSG+A A++A +DF L RVVV+LPDSVRNYMTKFLSDDWM +R M P + S ++ ++ SL+L AP+TV P V+V +TLEL +E DQVPVVE SSG I+GMAT+ I S +++ +L TDPV A + F KV ++ + +SR LD DHFVLVV QQRQ G E ++E +YGI+TRIDL++++++
Sbjct: 41 PNHDSRCTFRIDKPVCESPHLHQKRKERPKILPDILHHIGNTPLVRVNNITKEEGIECEILVKCEFFNAGGSVKDRIGLRMIEDAERSGRLKPGDVLIEPTSGNTGIGLALAAAVKGYRCTIVMPEKMSKEKVDVLRALGADIVRTPTAASYDSAESHIGVAKQLLNTVANSHILDQYTNPSNPMAHFDGTAEEILEACSGQLDMVVLGAGTGGTLCGVARKLKQRCPDCLIIGVDPLGSILAQPDELNATKVTGYDVEGIGYDFVPTVLDRSLVDRWYKSNDVDSLRMARRLIRREGLLCGGSSGSAFDCALRAVRDFGLGAGKRVVVLLPDSVRNYMTKFLSDDWMIERGHMPDPEDDPSLGPSHAWMSVRVGSLDLRAPLTVAPDVSVSETLELFNRESIDQVPVVERSSGAIVGMATLSNITSRIIRGSLAPTDPVGSAAFDKFTKVTPDAKLGAVSRRLDTDHFVLVVQQQRQFGSAG-EAVREFVYGILTRIDLLNFILK 545
BLAST of Cystathionine beta-synthase vs. TrEMBL
Match: A0A267G0J9 (Cystathionine beta-synthase (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000058g3 PE=3 SV=1) HSP 1 Score: 642.499 bits (1656), Expect = 0.000e+0 Identity = 316/506 (62.45%), Postives = 388/506 (76.68%), Query Frame = 3
Query: 123 PGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVE-SSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIE 1637
P S+CTF++D SPH ++ ++PKI+ +IL IG TPLV++N I K E I CEILVKCE+ N GGSVKDRI LRMIEDAE SG++KPGD LIEPTSGNTGIGLALAAAVKGY+C IVMPEKMS EKVDVLRALGA+IVRTPT+ASYDS ES+I VA +L + NSHIL+QYTNPSNP+AH+DGTAEEIL +C +DMVV+ AGTGGTL GVARK+KQ+CP CL++GVDP GSILAQP+ +N + VT Y+VEGIGYDFVPTVLDRS VD+WYK D DS MARRLIR EGLLCGGSSG+A A++A +DF L RVVV+LPDSVRNYMTKFLSDDWM +R M P + S ++ ++ SL+L AP+TV P V+V +TLEL +E DQVPVVE SSG I+GMAT+ I S +++ +L TDPV A + F KV ++ + +SR LD DHFVLVV QQRQ G E ++E +YGI+TRIDL++++++
Sbjct: 41 PNHDSRCTFRIDKPVCESPHLHQKRKERPKILPDILHHIGNTPLVRVNNITKEEGIECEILVKCEFFNAGGSVKDRIGLRMIEDAERSGRLKPGDVLIEPTSGNTGIGLALAAAVKGYRCTIVMPEKMSKEKVDVLRALGADIVRTPTAASYDSAESHIGVAKQLLNTVANSHILDQYTNPSNPMAHFDGTAEEILEACSGQLDMVVLGAGTGGTLCGVARKLKQRCPDCLIIGVDPLGSILAQPDELNATKVTGYDVEGIGYDFVPTVLDRSLVDRWYKSNDVDSLRMARRLIRREGLLCGGSSGSAFDCALRAVRDFGLGAGKRVVVLLPDSVRNYMTKFLSDDWMIERGHMPDPEDDPSLGPSHTWMSVRVGSLDLRAPLTVAPDVSVSETLELFNRESIDQVPVVERSSGAIVGMATLSNITSRIIRGSLAPTDPVGSAAFDKFTKVTPDAKLGAVSRRLDTDHFVLVVQQQRQFGSAG-EAVREFVYGILTRIDLLNFILK 545
BLAST of Cystathionine beta-synthase vs. Ensembl Cavefish
Match: cbsb (cystathionine beta-synthase [Source:NCBI gene;Acc:103030674]) HSP 1 Score: 591.267 bits (1523), Expect = 0.000e+0 Identity = 304/505 (60.20%), Postives = 384/505 (76.04%), Query Frame = 3
Query: 123 PGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKP--MTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P + S+CT+KLD SPH+ P I+ NIL IG TP+V +NKI K + CEIL KCE+ N GGSVKDRISLRM+EDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPN+HIL+QY NPSNPLAHYDGTAEEIL CD IDM+V AGTGGT+ G+ARK+K+KCP +VGVDP GS LA+PE +NK++ T YEVEGIGYDF+PTVLDRS VD WYK D +SF M+R LIR+EGLLCGGSSG+A+ AAV AK+ L + R VV+LPDSVRNYM+KFLSD WM ++ F+ + M N+ + + L L+AP+TV PSV ++ T+++LK++ FDQ PVV+ +G I+GM T+G ++S ++ + +DPV K +YK FK+V L + +LSR+L+ DHF LVVH+Q Q G+ LK+M++GIVT IDL++Y+
Sbjct: 90 PDLASRCTWKLDGPNVDSPHNHSIRTKAPHILPNILRKIGDTPMVHINKIPKTFGLKCEILAKCEFFNAGGSVKDRISLRMVEDAEEAGILKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNAHILDQYRNPSNPLAHYDGTAEEILEQCDGKIDMLVAGAGTGGTITGIARKLKEKCPNIKIVGVDPEGSTLAEPEDLNKTNKTAYEVEGIGYDFIPTVLDRSVVDSWYKSNDDESFAMSRMLIRDEGLLCGGSSGSAMAAAVTVAKE--LKEGQRCVVILPDSVRNYMSKFLSDKWMCEKGFLGEEDLMVNKP-----WWWNLTLQELRLSAPLTVLPSVNIKNTIKILKEKAFDQAPVVDEAGVILGMVTLGNMLSSVLAGKVSPSDPVIKVLYKQFKQVRLTDNLGKLSRILETDHFALVVHEQIQYMTDGSSTLKQMVFGIVTAIDLLNYV 587
BLAST of Cystathionine beta-synthase vs. Ensembl Cavefish
Match: cbsa (cystathionine beta-synthase a [Source:ZFIN;Acc:ZDB-GENE-050417-367]) HSP 1 Score: 590.497 bits (1521), Expect = 0.000e+0 Identity = 307/527 (58.25%), Postives = 397/527 (75.33%), Query Frame = 3
Query: 51 IPLNRKKMANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
I LNR K+A+ I+ P + SKCT++L + SPH+ I+ NIL IG TPLV++NKI K + CE+L KCEY N GGSVKDRISLRM+EDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V AGTGGT+ G+ARK+K+KCP ++ VDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VD WYK D++SF MAR LIR+EGLLCGGSSG A+ AAV+AAK+ L + R VV+LPDS+RNYM+KFLSD WM+ + F+ + S + ++ SLNL+AP+TV P+VT ++T+++LK++GFDQ PVV SG I+GM T+G +++ ++ + +DPVSK +YK FK++ L + +LSR+L+ DHF LVVH+Q Q G+ LK+M++G+VT IDL++++
Sbjct: 41 IQLNRDKVASERKWIR--------PDLSSKCTWRLGAPQTDSPHTHPPRIHASSILPNILQGIGDTPLVRINKITKTFGLKCEMLAKCEYFNAGGSVKDRISLRMVEDAERAGILKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSLEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNSHILDQYRNPSNPLAHYDTTAEEILEQCDGKVDMLVAGAGTGGTITGIARKLKEKCPNIKIIAVDPEGSILAEPEELNQTDKTQYEVEGIGYDFIPTVLDRTVVDSWYKTNDEESFAMARMLIRDEGLLCGGSSGTAMAAAVKAAKE--LKEGQRCVVILPDSIRNYMSKFLSDKWMFQKGFLTEEDIMVSKPW---WWNLRLQSLNLSAPLTVLPTVTCQKTIKILKEKGFDQAPVVNESGVILGMVTLGNMLASVLAGKVKPSDPVSKVLYKQFKQIRLTDNMGKLSRILETDHFALVVHEQIQYLTDGSTTLKQMVFGVVTAIDLLNFV 554
BLAST of Cystathionine beta-synthase vs. Ensembl Cavefish
Match: cbsa (cystathionine beta-synthase a [Source:ZFIN;Acc:ZDB-GENE-050417-367]) HSP 1 Score: 587.8 bits (1514), Expect = 0.000e+0 Identity = 308/532 (57.89%), Postives = 398/532 (74.81%), Query Frame = 3
Query: 51 IPLNRKKMANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIESTK 1646
I LNR K+A+ I+ P + SKCT++L + SPH+ I+ NIL IG TPLV++NKI K + CE+L KCEY N GGSVKDRISLRM+EDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V AGTGGT+ G+ARK+K+KCP ++ VDP GSILA+PE +N++ T YEVEGIGYDF+PTVLDR+ VD WYK D++SF MAR LIR+EGLLCGGSSG A+ AAV+AAK+ L + R VV+LPDS+RNYM+KFLSD WM+ + F+ + S + ++ SLNL+AP+TV P+VT ++T+++LK++GFDQ PVV SG I+GM T+G +++ ++ + +DPVSK +YK FK++ L + +LSR+L+ DHF LVVH+Q Q G+ LK+M++G+VT IDL++++ K
Sbjct: 41 IQLNRDKVASERKWIR--------PDLSSKCTWRLGAPQTDSPHTHPPRIHASSILPNILQGIGDTPLVRINKITKTFGLKCEMLAKCEYFNAGGSVKDRISLRMVEDAERAGILKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSLEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNSHILDQYRNPSNPLAHYDTTAEEILEQCD--VDMLVAGAGTGGTITGIARKLKEKCPNIKIIAVDPEGSILAEPEELNQTDKTQYEVEGIGYDFIPTVLDRTVVDSWYKTNDEESFAMARMLIRDEGLLCGGSSGTAMAAAVKAAKE--LKEGQRCVVILPDSIRNYMSKFLSDKWMFQKGFLTEEDIMVSKP---WWWNLRLQSLNLSAPLTVLPTVTCQKTIKILKEKGFDQAPVVNESGVILGMVTLGNMLASVLAGKVKPSDPVSKVLYKQFKQIRLTDNMGKLSRILETDHFALVVHEQIQYLTDGSTTLKQMVFGVVTAIDLLNFVTAREK 557
BLAST of Cystathionine beta-synthase vs. Ensembl Cavefish
Match: cbsb (cystathionine beta-synthase [Source:NCBI gene;Acc:103030674]) HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0 Identity = 294/509 (57.76%), Postives = 369/509 (72.50%), Query Frame = 3
Query: 123 PGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKP--MTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGM----ATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P + S+CT+KLD SPH+ P I+ NIL IG TP+V +NKI K + CEIL KCE+ N GGSVKDRISLRM+EDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPN+HIL+QY NPSNPLAHYDGTAEEIL CD IDM+V AGTGGT+ G+ARK+K+KCP +VGVDP GS LA+PE +NK++ T YEVEGIGYDF+PTVLDRS VD WYK D +SF M+R LIR+EGLLCGGSSG+A+ AAV AK+ L + R VV+LPDSVRNYM+KFLSD WM ++ F+ + M N+ + + L L+AP+TV PSV ++ T+++LK++ FDQ PVV+ +G +I + + S L P ++ V L + +LSR+L+ DHF LVVH+Q Q G+ LK+M++GIVT IDL++Y+
Sbjct: 90 PDLASRCTWKLDGPNVDSPHNHSIRTKAPHILPNILRKIGDTPMVHINKIPKTFGLKCEILAKCEFFNAGGSVKDRISLRMVEDAEEAGILKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNAHILDQYRNPSNPLAHYDGTAEEILEQCDGKIDMLVAGAGTGGTITGIARKLKEKCPNIKIVGVDPEGSTLAEPEDLNKTNKTAYEVEGIGYDFIPTVLDRSVVDSWYKSNDDESFAMSRMLIRDEGLLCGGSSGSAMAAAVTVAKE--LKEGQRCVVILPDSVRNYMSKFLSDKWMCEKGFLGEEDLMVNKP-----WWWNLTLQELRLSAPLTVLPSVNIKNTIKILKEKAFDQAPVVDEAGYVININHTENQIRFYQSNEHAPPFTLLLPPKSKVF----DVRLTDNLGKLSRILETDHFALVVHEQIQYMTDGSSTLKQMVFGIVTAIDLLNYV 587
BLAST of Cystathionine beta-synthase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006465.1 (pep scaffold:Pmarinus_7.0:GL485116:3950:11309:-1 gene:ENSPMAG00000005834.1 transcript:ENSPMAT00000006465.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 174.481 bits (441), Expect = 3.360e-51 Identity = 95/217 (43.78%), Postives = 144/217 (66.36%), Query Frame = 3
Query: 1017 LLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFM-------DKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIESTK 1646
++ GGSSG+A+ AAV+AAK +L + R VV+LPDS+RNYMTKFLSD WM + F+ +KP ++ K+ L L+AP+TV P+V+ ++T+ LL+++G+DQVPVV S+G ++GM T+G ++S + + +DPVSK +YK FK++ L + +LSR+L+ DHF LVVH Q Q G + + M++GIVT IDL++Y+ K
Sbjct: 1 MVAGGSSGSAMVAAVEAAK--SLREGQRCVVLLPDSIRNYMTKFLSDHWMAQKGFLPEEDYLPNKPWW----------WDMKVQDLCLSAPLTVLPTVSCQETMALLREKGYDQVPVVNSAGLVLGMVTLGNMLSCTLAGKVKPSDPVSKILYKQFKQITLKDNLGKLSRILETDHFALVVHDQIQYRGQGHSQKQNMVFGIVTAIDLLNYVTTREK 205
BLAST of Cystathionine beta-synthase vs. Ensembl Yeast
Match: CYS4 (Cystathionine beta-synthase; catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; advances passage through START by promoting cell growth which requires catalytic activity, and reducing critical cell size independent of catalytic activity; mutations in human ortholog CBS cause homocystinuria; human CBS can complement yeast null mutant [Source:SGD;Acc:S000003387]) HSP 1 Score: 384.415 bits (986), Expect = 2.451e-128 Identity = 221/505 (43.76%), Postives = 313/505 (61.98%), Query Frame = 3
Query: 222 NILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPG-DTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCD--NIID---MVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDF-NLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMD---------KPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLV---LTDPVSKAIYKNFKKVNLNSTIQQL----------------SRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
N++ +G TPL+ L K+ K I +I K E NPGGS+KDRI+ M+E+AEASG+I P TLIEPTSGNTGIGLAL A+KGY+ II +PEKMS EKV VL+ALGAEI+RTPT+A++DSPES+I VA +L++EIP + IL+QY N NP AHY GT EI + N+ D VV AGTGGT++G+++ +K++ K +VG DPFGSILAQPE++NK+ +T Y+VEGIGYDFVP VLDR +D WYK DK SF AR+LI EG+L GGSSG+A A V+ +D L + +V + PDS+R+Y+TKF+ D+W+ N D + + +V + L+L ++V+ + V +++LK GFDQ+PV+ G + G+ T +S L++K + D K Y +FKK+N + + S+L D++ F ++ + T+ LK + IVT++DL+SY+
Sbjct: 13 NVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIHPSRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAWDSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAVVAGAGTGGTISGISKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGYDFVPQVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCEDHPELTEDDVIVAIFPDSIRSYLTKFVDDEWLKKNNLWDDDVLARFDSSKLEASTTKYADVFGNATVKDLHLKPVVSVKETAKVTDVIKILKDNGFDQLPVLTEDGKLSGLVT----LSELLRKLSINNSNNDNTIKGKYLDFKKLNNFNDVSSYNENKSGKKKFIKFDENSKLSDLNRFF-----EKNSSAVITDGLKPI--HIVTKMDLLSYL 506
BLAST of Cystathionine beta-synthase vs. Ensembl Yeast
Match: MCY1 (Putative cysteine synthase; localized to the mitochondrial outer membrane [Source:SGD;Acc:S000003244]) HSP 1 Score: 120.168 bits (300), Expect = 4.928e-30 Identity = 105/342 (30.70%), Postives = 168/342 (49.12%), Query Frame = 3
Query: 201 DKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGD--TLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSH------ILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCP-KCLVVGVDPFGSIL------------AQPESINKSSVTFYEVEGIGYDFVPT--VLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSD 1157
D P+ + + IG TPLVK+ + K ++ I K E NP GS KDR++L +I+ AE G++ G+ + E TSG+TGI +A+ GY+ I +P+ S+EK+ +L +LGA + + ++ D P ++ A + E+ S +Q+ N +N HY T EI ID + GTGGT+ GVA+ +K++ C VV DP GS + E + VEGIG + + + F+D+ +V D + MA+ L +GL G S+ AA+Q AK LP + +V++ DS +++KF +
Sbjct: 41 DIPRPKEGVEELIGNTPLVKIRSLTKATGVN--IYAKLELCNPAGSAKDRVALNIIKTAEELGELVRGEPGWVFEGTSGSTGISIAVVCNALGYRAHISLPDDTSLEKLALLESLGATVNKVKPASIVD-PNQYVNAAKKACNELKKSGNGIRAVFADQFENEANWKVHYQTTGPEIAHQTKGNIDAFIAGCGTGGTITGVAKFLKERAKIPCHVVLADPQGSGFYNRVNYGVMYDYVEKEGTRRRHQVDTIVEGIGLNRITHNFHMGEKFIDESIRVNDNQAIRMAKYLSVNDGLFVGSSTAINAVAAIQVAK--TLPHGSNIVIIACDSGSRHLSKFWKE 377
BLAST of Cystathionine beta-synthase vs. Ensembl Nematostella
Match: EDO43469 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYI9]) HSP 1 Score: 600.897 bits (1548), Expect = 0.000e+0 Identity = 316/518 (61.00%), Postives = 394/518 (76.06%), Query Frame = 3
Query: 93 IKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIH-DKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQR-QITPTGTEELKEMIYGIVTRIDLISYMIES 1640
+K ++ P + SKCT+ L ++ A SPH ++ KIM NIL IG TPLV++N IGK + CE+L KCE+ N GGSVKDRI LRMIE+AE G++KPGDTLIEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS EKVDVLRALGAEIVRTPT A +DSPES+I VA RL EI NSHIL+QY NP NPLAHYD TA+EIL CD +DMVV+ AGTGGT+ G+ARK+K+KCP +VGVDP GSILA+PES+N+S V+ Y VEGIGYDFVPTVLDRS VDKWYK DK SF M+RRLIREEGLLCGGSSG+A+ AAV+AAK N + R VV+LPDSVRNYMTKFLSDDWM ++ F++ P TN D ++K++ +LN P++V PS++ + ++++ +EG+DQ+PVV +G ++GM T+G IMS ++ + +D VSK IYKNFKKV L + + LSR+LD DH+ LVVH QR I P E KEM++GIVTR+DL++Y+ S
Sbjct: 17 LKGKERKWIRPDLKSKCTWHLGANLADSPHHHEKARVPSSKIMPNILQKIGDTPLVRINNIGKTYGLKCELLAKCEFFNAGGSVKDRIGLRMIEEAEREGRLKPGDTLIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSNEKVDVLRALGAEIVRTPTEAKFDSPESHIGVAQRLNAEIANSHILDQYRNPGNPLAHYDSTADEILQQCDGKVDMVVLGAGTGGTITGIARKLKEKCPGVTIVGVDPKGSILAEPESLNESDVSMYHVEGIGYDFVPTVLDRSVVDKWYKSEDKTSFTMSRRLIREEGLLCGGSSGSAMVAAVEAAKSLN--EGQRCVVILPDSVRNYMTKFLSDDWMTEKGFVE-PNTN-GFDSKLWWWKKQLHALNPPTPLSVLPSISCQHCIDIMSREGYDQLPVVNEAGGVLGMLTLGNIMSHIIAGRMKPSDSVSKCIYKNFKKVTLETNLGTLSRILDHDHYALVVHSQRVYIAPDKVTE-KEMVFGIVTRVDLLNYITRS 529
BLAST of Cystathionine beta-synthase vs. Ensembl Nematostella
Match: EDO42437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1D2]) HSP 1 Score: 449.899 bits (1156), Expect = 4.239e-153 Identity = 246/493 (49.90%), Postives = 338/493 (68.56%), Query Frame = 3
Query: 168 ATSPHSKKEIHDKP-KIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTF--YEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIE 1637
ATSPH + DK KI+ N+L IG TP++++N +GK + CE++ KCE++NP GS+KDRI +RMIEDAE IKPGDTLIEPTSGNTGI LALA+AVKGY+C+IVM EKMS +K D +ALG VR P A +DSPES I +A +L++EIPNS++LNQY NPSNPLAHYDGTAEEIL CD +DM+VI GTGGTL GVARKI++K P +V VDP+GS+LA PE +NK+ F Y VEGIG +VP VLDR VD+W K+GDK++F A+RL +EEGLL GGSSG+ + AAV+AA+D L ++ R VVV DS+RNYM+KF+SD+W+ +RN + + ND + +K+SSL+L V ++TV+ L G +V V ++ G I+G+ T G +++ + ++ + K IYK F +V+ +++++++SR LD D+FVLV Q + +VTR L++++IE
Sbjct: 47 ATSPHFHEPPPDKNNKILPNVLHSIGNTPMIRINNVGKRCGLKCEVVAKCEFMNPVGSLKDRIGVRMIEDAERDNHIKPGDTLIEPTSGNTGIALALASAVKGYRCVIVMSEKMSSDKADTQKALGGICVRAPAEAKFDSPESTIRLAQQLQKEIPNSYVLNQYRNPSNPLAHYDGTAEEILQQCDGKLDMLVIGTGTGGTLTGVARKIREKLPHVKIVAVDPYGSVLAVPEELNKTEPGFKGYNVEGIGKPYVPVVLDRDLVDEWQKIGDKEAFYFAKRLSKEEGLLVGGSSGSVMAAAVRAAQD--LDENQRCVVVFADSIRNYMSKFVSDEWLEERNLQHDDIND--NDPQHWWLSEKVSSLSLPFSAPVSSNLTVKDLLAFFSNGGNQEVAVQDNKGRILGIVTHGNLLASEAAGRVDMSSTLEKLIYKKFDQVSRDTSLEKVSRCLDNDYFVLVPGCDSQ------------EFSVVTRGHLLNFIIE 523
BLAST of Cystathionine beta-synthase vs. Ensembl Nematostella
Match: EDO37028 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SH12]) HSP 1 Score: 147.132 bits (370), Expect = 5.601e-41 Identity = 93/196 (47.45%), Postives = 121/196 (61.73%), Query Frame = 3
Query: 246 TPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDP 833
TPL++LNK+ ++ C I VK E+LNPGGSVKDR +L +I++AE G +KPG T++E T+GNTGIGLA KGYKC+I MP S EK+D+L+ALGAE+ P +D + A R + I N NQ+ N +N AH++ T EI D ID VV GTGGTLAGV +K K P V+ DP
Sbjct: 10 TPLIRLNKLS--DETGCNITVKGEHLNPGGSVKDRAALFLIKEAEEKGLLKPGGTVVEGTAGNTGIGLAHICLAKGYKCVIYMPNNQSQEKMDLLKALGAEVRPVPV-VPFDDQMNYNHQARRYAESIENGVWTNQFDNTANRRAHFETTGPEIWQQTDGQIDAVVFGTGTGGTLAGVGSFLKSKNPNVKVILADP 202
BLAST of Cystathionine beta-synthase vs. Ensembl Medaka
Match: ENSORLT00000044153.1 (cystathionine beta-synthase [Source:NCBI gene;Acc:101158999]) HSP 1 Score: 590.112 bits (1520), Expect = 0.000e+0 Identity = 297/510 (58.24%), Postives = 391/510 (76.67%), Query Frame = 3
Query: 102 PLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P ++ P + S+C + L + A SPH + P ++ NIL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRM+EDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V AGTGGT+ G+ARK+K+KCP +V VDP GSILA+PE +NK+ T YEVEGIGYDF+PTVLDRS VD WYK D++SFNM+R LIREEGLLCGGSSG A+ AAV AK+ L + R VV+LPDS+RNYM+KFLSD WM+++ F+ + + + + K+ LN++AP+TV P+V+ + T+++LK++GFDQ PVV+ +G I+GM T+G ++S ++ + L+DPVSK +YK F+++ L + +LSR+L+ DHF LVVH+Q Q G+ LK+M++G+VT +DL++++
Sbjct: 28 PERKWIRPDLPSRCKWSLGASQADSPH----LAPTPTVLPNILHRIGDTPMVRINKIPKAFGLKCELLAKCEFFNAGGSVKDRISLRMVEDAERAGILKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNSHILDQYRNPSNPLAHYDSTAEEILEQCDGKVDMLVAGAGTGGTITGIARKLKEKCPNVKIVAVDPEGSILAEPEHLNKTDKTQYEVEGIGYDFIPTVLDRSVVDTWYKSNDEESFNMSRMLIREEGLLCGGSSGTAMAAAVAVAKE--LKEGQRCVVILPDSIRNYMSKFLSDKWMFEKGFLSEEVLMV---KKPWWWNLKLQGLNMSAPLTVLPTVSCQNTIKILKEKGFDQAPVVDDAGLILGMVTLGNMLSSILAGKIRLSDPVSKVLYKQFRQIRLTDNLGKLSRILETDHFALVVHEQIQYLTDGSAVLKQMVFGVVTAVDLLNFV 528
BLAST of Cystathionine beta-synthase vs. Ensembl Medaka
Match: ENSORLT00000043890.1 (cystathionine beta-synthase [Source:NCBI gene;Acc:101158999]) HSP 1 Score: 583.178 bits (1502), Expect = 0.000e+0 Identity = 299/520 (57.50%), Postives = 391/520 (75.19%), Query Frame = 3
Query: 102 PLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQI----TPT------GTEELKEMIYGIVTRIDLISYM 1631
P ++ P + S+C + L + A SPH + P ++ NIL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRM+EDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V AGTGGT+ G+ARK+K+KCP +V VDP GSILA+PE +NK+ T YEVEGIGYDF+PTVLDRS VD WYK D++SFNM+R LIREEGLLCGGSSG A+ AAV AK+ L + R VV+LPDS+RNYM+KFLSD WM+++ + + R + K+ LN++AP+TV P+V+ + T+++LK++GFDQ PVV+ +G I+GM T+G ++S ++ + L+DPVSK +YK F+++ L + +LSR+L+ DHF LVVH+Q Q TP G+ LK+M++G+VT +DL++++
Sbjct: 62 PERKWIRPDLPSRCKWSLGASQADSPH----LAPTPTVLPNILHRIGDTPMVRINKIPKAFGLKCELLAKCEFFNAGGSVKDRISLRMVEDAERAGILKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNSHILDQYRNPSNPLAHYDSTAEEILEQCDGKVDMLVAGAGTGGTITGIARKLKEKCPNVKIVAVDPEGSILAEPEHLNKTDKTQYEVEGIGYDFIPTVLDRSVVDTWYKSNDEESFNMSRMLIREEGLLCGGSSGTAMAAAVAVAKE--LKEGQRCVVILPDSIRNYMSKFLSDKWMFEKEALVRVT------RGWEWWNLKLQGLNMSAPLTVLPTVSCQNTIKILKEKGFDQAPVVDDAGLILGMVTLGNMLSSILAGKIRLSDPVSKVLYKQFRQIRLTDNLGKLSRILETDHFALVVHEQIQCKSADTPVRIYLTDGSAVLKQMVFGVVTAVDLLNFV 569
BLAST of Cystathionine beta-synthase vs. Ensembl Medaka
Match: ENSORLT00000034391.1 (pep primary_assembly:ASM223467v1:16:223684:225405:1 gene:ENSORLG00000023606.1 transcript:ENSORLT00000034391.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0 Identity = 278/493 (56.39%), Postives = 372/493 (75.46%), Query Frame = 3
Query: 153 LDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
L + A SPH + P ++ NIL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRM+ED E +G +KPGDT+IEPT+GNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIV TPTSA +DSPES++ VA LK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V A TGGT+ +ARK+K KCP +VGVDP GSILA+PE +NK+ YEVEGIGYDF+PTVLDRS VD WYK ++SFNM+R LIRE+GLLCGGSSG A+ AAV K+ L + R VV+LP+S+RNYM+KFL+D WM+++ F+ + + + + K+ LN++AP+TV P+V+ + T+++LK++GFDQ PVV+ +G I+GM T+G ++S ++ + L++P+SK YK F+++ L + +LSR+ + DHF LVVH+Q Q G+ LK+M++G++T +DL++++
Sbjct: 41 LGASQADSPHLQIPRAPTPTVLPNILHRIGDTPMVRINKIPKDFGLKCELLAKCEFFNAGGSVKDRISLRMVEDGERAGILKPGDTIIEPTAGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVCTPTSARFDSPESHVGVAWCLKNEIPNSHILDQYRNPSNPLAHYDSTAEEILEQCDGKVDMLVAGACTGGTI--IARKLKDKCPNVKIVGVDPEGSILAEPEHLNKTDKAQYEVEGIGYDFIPTVLDRSVVDTWYKSNGEESFNMSRMLIREKGLLCGGSSGTAMAAAVVVTKE--LKEGQRCVVILPNSIRNYMSKFLNDKWMFEKGFLSEGVLMV---KKPWWWNLKLQGLNMSAPLTVLPTVSCQNTIKILKEKGFDQAPVVDDAGFILGMVTLGNMLSSILAGKIRLSNPISKVYYKQFRQIRLTDNLGKLSRIPETDHFALVVHEQIQYLTDGSAVLKQMVFGMITAVDLLNFV 526
BLAST of Cystathionine beta-synthase vs. Ensembl Medaka
Match: ENSORLT00000033433.1 (cystathionine beta-synthase [Source:NCBI gene;Acc:101158999]) HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0 Identity = 292/510 (57.25%), Postives = 379/510 (74.31%), Query Frame = 3
Query: 102 PLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P ++ P + S+C + L + A SPH + P ++ NIL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRM+EDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V AGTGGT+ G+ARK+K+KCP +V VDP GSILA+PE +NK+ T YEVEGIGYDF+PTVLDRS VD WYK D++SFNM+R LIREEGLLCGGSSG A+ AAV AK+ L + R VV+LPDS+RNYM+ R D R + K+ LN++AP+TV P+V+ + T+++LK++GFDQ PVV+ +G I+GM T+G ++S ++ + L+DPVSK +YK F+++ L + +LSR+L+ DHF LVVH+Q Q G+ LK+M++G+VT +DL++++
Sbjct: 46 PERKWIRPDLPSRCKWSLGASQADSPHLQIPRAPTPTVLPNILHRIGDTPMVRINKIPKAFGLKCELLAKCEFFNAGGSVKDRISLRMVEDAERAGILKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNSHILDQYRNPSNPLAHYDSTAEEILEQCDGKVDMLVAGAGTGGTITGIARKLKEKCPNVKIVAVDPEGSILAEPEHLNKTDKTQYEVEGIGYDFIPTVLDRSVVDTWYKSNDEESFNMSRMLIREEGLLCGGSSGTAMAAAVAVAKE--LKEGQRCVVILPDSIRNYMSLI--------RGGFDGEEALVRVTRGWEWWNLKLQGLNMSAPLTVLPTVSCQNTIKILKEKGFDQAPVVDDAGLILGMVTLGNMLSSILAGKIRLSDPVSKVLYKQFRQIRLTDNLGKLSRILETDHFALVVHEQIQYLTDGSAVLKQMVFGVVTAVDLLNFV 545
BLAST of Cystathionine beta-synthase vs. Ensembl Medaka
Match: ENSORLT00000043729.1 (cystathionine beta-synthase [Source:NCBI gene;Acc:101158999]) HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0 Identity = 292/510 (57.25%), Postives = 379/510 (74.31%), Query Frame = 3
Query: 102 PLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYM 1631
P ++ P + S+C + L + A SPH + P ++ NIL IG TP+V++NKI K + CE+L KCE+ N GGSVKDRISLRM+EDAE +G +KPGDT+IEPTSGNTGIGLALAAAVKGY+CIIVMPEKMS+EKVDVLRALGAEIVRTPTSA +DSPES++ VA RLK EIPNSHIL+QY NPSNPLAHYD TAEEIL CD +DM+V AGTGGT+ G+ARK+K+KCP +V VDP GSILA+PE +NK+ T YEVEGIGYDF+PTVLDRS VD WYK D++SFNM+R LIREEGLLCGGSSG A+ AAV AK+ L + R VV+LPDS+RNYM +R D R + K+ LN++AP+TV P+V+ + T+++LK++GFDQ PVV+ +G I+GM T+G ++S ++ + L+DPVSK +YK F+++ L + +LSR+L+ DHF LVVH+Q Q G+ LK+M++G+VT +DL++++
Sbjct: 62 PERKWIRPDLPSRCKWSLGASQADSPH----LAPTPTVLPNILHRIGDTPMVRINKIPKAFGLKCELLAKCEFFNAGGSVKDRISLRMVEDAERAGILKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNSHILDQYRNPSNPLAHYDSTAEEILEQCDGKVDMLVAGAGTGGTITGIARKLKEKCPNVKIVAVDPEGSILAEPEHLNKTDKTQYEVEGIGYDFIPTVLDRSVVDTWYKSNDEESFNMSRMLIREEGLLCGGSSGTAMAAAVAVAKE--LKEGQRCVVILPDSIRNYM--------FPERGGFDGEEALVRVTRGWEWWNLKLQGLNMSAPLTVLPTVSCQNTIKILKEKGFDQAPVVDDAGLILGMVTLGNMLSSILAGKIRLSDPVSKVLYKQFRQIRLTDNLGKLSRILETDHFALVVHEQIQYLTDGSAVLKQMVFGVVTAVDLLNFV 557
BLAST of Cystathionine beta-synthase vs. Planmine SMEST
Match: SMESG000065264.1 (SMESG000065264.1) HSP 1 Score: 1034.63 bits (2674), Expect = 0.000e+0 Identity = 518/528 (98.11%), Postives = 519/528 (98.30%), Query Frame = 3
Query: 72 MANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIESTKAIG 1655
MANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGAAVYAAVQAAKDFNLPQ ARVVVVLPDSVRNYMTKFLSDDWMY+RNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKK QLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIESTKAIG
Sbjct: 1 MANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGAAVYAAVQAAKDFNLPQPARVVVVLPDSVRNYMTKFLSDDWMYNRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKK--------QLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIESTKAIG 520
BLAST of Cystathionine beta-synthase vs. Planmine SMEST
Match: SMESG000050056.1 (SMESG000050056.1) HSP 1 Score: 819.691 bits (2116), Expect = 0.000e+0 Identity = 424/532 (79.70%), Postives = 458/532 (86.09%), Query Frame = 3
Query: 45 FQIPLNRKKMANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIES 1640
QI + RK + N I SIKSPL QFPN G K TF++ S+P S KE DKPKIMDNILLDIG TPLVKLN IGK E + CEILVKCEYLNPGGSVK+RISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDN IDM+V GTGGTL G+A+KIKQ+CPKCLV+GVDP GSI+A+ ES+N S + FYE+EGIG DF+PTVLD S +DKWYKV DK+SF MARRLIREEGLLCGGSSG AVYAAVQAAKDFNLP++ARVVVVLPDSVRNYM N++EFE+KIS LNLNAP+TVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTL LTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQI +G+EELKE +YGI+TRIDL++Y+I+S
Sbjct: 8 LQIFMKRKVLDNQISSIKSPLKQFPNSGKLGKFTFQVASEPEKSSRGTKERQDKPKIMDNILLDIGNTPLVKLNSIGKAENVLCEILVKCEYLNPGGSVKERISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNNIDMIVAGVGTGGTLTGIAKKIKQQCPKCLVIGVDPIGSIVAELESMNNSKIAFYEIEGIGGDFLPTVLDHSIIDKWYKVDDKESFLMARRLIREEGLLCGGSSGTAVYAAVQAAKDFNLPKTARVVVVLPDSVRNYM--------------------------NDIEFEEKISLLNLNAPITVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLALTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQICSSGSEELKETLYGIITRIDLVTYLIDS 513
BLAST of Cystathionine beta-synthase vs. Planmine SMEST
Match: SMESG000050056.1 (SMESG000050056.1) HSP 1 Score: 814.298 bits (2102), Expect = 0.000e+0 Identity = 424/534 (79.40%), Postives = 458/534 (85.77%), Query Frame = 3
Query: 45 FQIPLNRKKMANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCL--VVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCGGSSGXXXXXXXXXXKDFNLPQSARVVVVLPDSVRNYMTKFLSDDWMYDRNFMDKPMTNQSNDRNNVEFEKKISSLNLNAPMTVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLVLTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQITPTGTEELKEMIYGIVTRIDLISYMIES 1640
QI + RK + N I SIKSPL QFPN G K TF++ S+P S KE DKPKIMDNILLDIG TPLVKLN IGK E + CEILVKCEYLNPGGSVK+RISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDN IDM+V GTGGTL G+A+KIKQ+CPKCL V+GVDP GSI+A+ ES+N S + FYE+EGIG DF+PTVLD S +DKWYKV DK+SF MARRLIREEGLLCGGSSG AVYAAVQAAKDFNLP++ARVVVVLPDSVRNYM N++EFE+KIS LNLNAP+TVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTL LTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQI +G+EELKE +YGI+TRIDL++Y+I+S
Sbjct: 8 LQIFMKRKVLDNQISSIKSPLKQFPNSGKLGKFTFQVASEPEKSSRGTKERQDKPKIMDNILLDIGNTPLVKLNSIGKAENVLCEILVKCEYLNPGGSVKERISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNNIDMIVAGVGTGGTLTGIAKKIKQQCPKCLVSVIGVDPIGSIVAELESMNNSKIAFYEIEGIGGDFLPTVLDHSIIDKWYKVDDKESFLMARRLIREEGLLCGGSSGTAVYAAVQAAKDFNLPKTARVVVVLPDSVRNYM--------------------------NDIEFEEKISLLNLNAPITVQPSVTVEQTLELLKKEGFDQVPVVESSGCIIGMATVGLIMSMLMKKTLALTDPVSKAIYKNFKKVNLNSTIQQLSRLLDIDHFVLVVHQQRQICSSGSEELKETLYGIITRIDLVTYLIDS 515
BLAST of Cystathionine beta-synthase vs. Planmine SMEST
Match: SMESG000065258.1 (SMESG000065258.1) HSP 1 Score: 526.939 bits (1356), Expect = 0.000e+0 Identity = 265/328 (80.79%), Postives = 286/328 (87.20%), Query Frame = 3
Query: 45 FQIPLNRKKMANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCG 1028
QI + RK + N I SIKSPL QFPN G K TF++ S+P S KE DKPKIMDNILLDIG TPLVKLN IGK E + CEILVKCEYLNPGGSVK+RISL+MIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDN IDM+V GTGGTL G+A+KIKQ+CPKCLV+GVDP GSI+A+ ES+N S + FYE+EGIG DF+PTVLD S +DKWYKV DK+SF MARRLIREEGLLCG
Sbjct: 8 LQIFMKRKVLDNQISSIKSPLKQFPNSGKLGKFTFQVASEPEKSSRGTKERQDKPKIMDNILLDIGNTPLVKLNSIGKAENVLCEILVKCEYLNPGGSVKERISLKMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNNIDMIVAGVGTGGTLTGIAKKIKQQCPKCLVIGVDPIGSIVAELESMNNSKIAFYEIEGIGGDFLPTVLDHSIIDKWYKVDDKESFLMARRLIREEGLLCG 335
BLAST of Cystathionine beta-synthase vs. Planmine SMEST
Match: SMESG000065258.1 (SMESG000065258.1) HSP 1 Score: 523.087 bits (1346), Expect = 0.000e+0 Identity = 263/324 (81.17%), Postives = 284/324 (87.65%), Query Frame = 3
Query: 57 LNRKKMANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDNILLDIGLTPLVKLNKIGKIEKISCEILVKCEYLNPGGSVKDRISLRMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNIIDMVVISAGTGGTLAGVARKIKQKCPKCLVVGVDPFGSILAQPESINKSSVTFYEVEGIGYDFVPTVLDRSFVDKWYKVGDKDSFNMARRLIREEGLLCG 1028
+ RK + N I SIKSPL QFPN G K TF++ S+P S KE DKPKIMDNILLDIG TPLVKLN IGK E + CEILVKCEYLNPGGSVK+RISL+MIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDN IDM+V GTGGTL G+A+KIKQ+CPKCLV+GVDP GSI+A+ ES+N S + FYE+EGIG DF+PTVLD S +DKWYKV DK+SF MARRLIREEGLLCG
Sbjct: 1 MKRKVLDNQISSIKSPLKQFPNSGKLGKFTFQVASEPEKSSRGTKERQDKPKIMDNILLDIGNTPLVKLNSIGKAENVLCEILVKCEYLNPGGSVKERISLKMIEDAEASGKIKPGDTLIEPTSGNTGIGLALAAAVKGYKCIIVMPEKMSIEKVDVLRALGAEIVRTPTSASYDSPESNISVAHRLKQEIPNSHILNQYTNPSNPLAHYDGTAEEILLSCDNNIDMIVAGVGTGGTLTGIAKKIKQQCPKCLVIGVDPIGSIVAELESMNNSKIAFYEIEGIGGDFLPTVLDHSIIDKWYKVDDKESFLMARRLIREEGLLCG 324 The following BLAST results are available for this feature:
BLAST of Cystathionine beta-synthase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cystathionine beta-synthase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cystathionine beta-synthase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of Cystathionine beta-synthase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cystathionine beta-synthase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of Cystathionine beta-synthase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cystathionine beta-synthase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cystathionine beta-synthase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cystathionine beta-synthase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 4
BLAST of Cystathionine beta-synthase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Cystathionine beta-synthase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Cystathionine beta-synthase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Cystathionine beta-synthase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Cystathionine beta-synthase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033930 ID=SMED30033930|Name=Cystathionine beta-synthase|organism=Schmidtea mediterranea sexual|type=transcript|length=1772bpback to top protein sequence of SMED30033930-orf-1 >SMED30033930-orf-1 ID=SMED30033930-orf-1|Name=SMED30033930-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=529bp MANPIPSIKSPLSQFPNPGMGSKCTFKLDSDPATSPHSKKEIHDKPKIMDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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