PKD2L-2

Overview
NamePKD2L-2 (AKN21732.1)
Smed IDSMED30033924
Length (bp)2945
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of PKD2L-2 (SMED30033924) t-SNE clustered cells

Violin plots show distribution of expression levels for PKD2L-2 (SMED30033924) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PKD2L-2 (SMED30033924) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PKD2L-2 (SMED30033924) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30033924

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 14

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30033924h1SMcG0003676 SmedASXL_014783SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30033924h1SMcG0003676 dd_Smed_v4_9977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30033924h1SMcG0003676 dd_Smed_v4_9977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30033924h1SMcG0003676 dd_Smed_v4_9977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
non-ciliated neuronSMED30033924h1SMcG0003676 dd_Smed_v4_9977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30033924h1SMcG0003676 dd_Smed_v4_9977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033924h1SMcG0003676 Contig35730uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033924h1SMcG0003676 Contig35730newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30033924h1SMcG0003676 dd_Smed_v6_9977_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
neuronSMED30033924h1SMcG0003676 dd_Smed_v6_9977_0_3dd_Smed_v6PMID:30399335
Ross et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30033924h1SMcG0003676 OX_Smed_1.0.14794ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
head regionSMED30033924h1SMcG0003676 OX_Smed_1.0.14718ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
neuronSMED30033924h1SMcG0003676 dd_Smed_v6_9977_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
GABAergic neuronSMED30033924h1SMcG0003676 dd_Smed_v6_9977_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of PKD2L-2 vs. Ensembl Human
Match: PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9011])

HSP 1 Score: 499.59 bits (1285), Expect = 1.007e-162
Identity = 291/686 (42.42%), Postives = 448/686 (65.31%), Query Frame = 2
Query:  527 QEIGFKNE--NCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAE---TEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQP--------------ISYGKYMGLSRHIDDLENIIEILTQKFDII 2527
            QE  ++ +  +C      GIR LW T  TEN  E++ LY  TT+REL+VY++FLV + ++T+ M     +Y+T  ++ LFL T  +D   +F ++ + +DFW F  GPLL+ LYW  WYN++++     ++IY+EN LLGVPR+RQ++V+N+SC++    +  +  CY  YS + E +  FG  N +AW Y     L   S  G++T+Y GGG+Y+DL  S++ S   + +L    WLDR TR V +DF++YNANINLFC+++LV EFP  GG +PS++ RTVKLIRYV+  DFF++ CE++F +++ YY++EE++E+  H+  Y  S+WN+LD++V+ L ++ V FHI+R   +  ++ KLL+  N + +FE+L+FWQ QY+N++A  LF A  KIFKYISFNK MTQL STL  C KD++GF++MFFIVF A+AQ GYL+FG+Q+ N+  F  CIFT FRIIL D ++  +   N ILGP YF+ YVFFVFF+L NMFLAI++D Y ++KEEL  +++E +++D LK+   K   +L L++E++ D++  ++      +  + F+++   L+  G+AE   TE+ + F KFD DG+R+LDE+EQ KM ++L +++ AL TE+       EKL  S    P              +S  ++  L+R +  LE ++E +  + D +
Sbjct:   58 QETAYRTQVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTP-SDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQ----GGEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEI-------EKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAV 731          
BLAST of PKD2L-2 vs. Ensembl Human
Match: PKD2 (polycystin 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9009])

HSP 1 Score: 460.299 bits (1183), Expect = 8.356e-146
Identity = 288/727 (39.61%), Postives = 457/727 (62.86%), Query Frame = 2
Query:  575 GIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALE------TELIEERDNQEKL----------------IESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFS---MMVENSEDYRKEKIEAIIQDELYK 2677
            G+R LW T+  E    ++  Y  + +RELV Y+LFL++L I+T+ M    ++Y+T  ++ LFL T  +    T F +L +  DFWKF  G LL+GLYW +   S    A+ +++I++EN LLGVPRIRQ+RV+N SC IP  L++++ +CY  YS + E +  FG +N +AW YT +  L   S  G I TY G G+Y+DL+ ++E +   + SL  N WLDR TRA  +DF++YNANINLFC+++L+ EFP  GGV+PS++F+ +KLIRYV   DFF+ ACEI+F  ++ YY++EE++EI  HK  YF S WN LDV+++ L V+ +  +IYR   ++ +L + LE+ N  PNFE+L++WQ+Q++N++A  +F    K+FK+I+FN+ M+QL +T++ C KDL GF++MFFI+FLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D NF E+   N +LGP+YF  +VFF+FFIL NMFLAI++D Y ++K +L +++ E E++D +++   K   KL LK+  + D+  +++       G ++FDE + +LK +G+ + EIE++F K+D DGD+ L E E  +M  +L  ++  L+         +  R     L                        +SY ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+  +    +  +SE +R E++E ++++EL +
Sbjct:  196 GLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKM-QPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLL-QFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLR----QGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHR-EQMERLVREELER 915          
BLAST of PKD2L-2 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012])

HSP 1 Score: 343.199 bits (879), Expect = 1.624e-105
Identity = 233/563 (41.39%), Postives = 358/563 (63.59%), Query Frame = 2
Query:  593 ATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNM-PANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKX-XXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIE 2272
            A+KH       K +   TT++EL++Y +FL+ L I+TF M   +M+Y    +++LFL T       T F S+++ +DFWKF+ GPLL GLYW+ WYN++ +      + IY+EN LLGVPR+RQ++V+NN+C + +  Q+ +++CY  Y+   E   +FG Q ++ W Y+  +   S    G +  Y  GG+   L+ S+  + N  + L  N W+ R TR + +DF++YNAN+NLFCII+LV EFP  GG+L S++F +VKL+RYV+  D+F+ +CEI F ++L  +  +E+ +I + KSAYF S+WN L++++L L  + VSF+ Y    I  +L +LL++   + +F +L+ W + Y+N+ A  +F A  KIFK+ISFNK M+QL STL+ C+KD+VGF++MFFI+F A+AQ G+L+FGSQ+ ++  F   IF  FRI+L D NF  +   NPILGP+YFI ++FFVFF+L NMFLAI++D Y ++K      +  +FE+   +K+  + V EK  LK+        A K  D    G  D  E   + +R G+ E EI+
Sbjct:   12 ASKH--KLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNT-NSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKK--------AQKDEDKKTKGSGDLAE---QARREGFDENEIQ 560          
BLAST of PKD2L-2 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012])

HSP 1 Score: 342.813 bits (878), Expect = 2.175e-105
Identity = 233/563 (41.39%), Postives = 358/563 (63.59%), Query Frame = 2
Query:  593 ATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNM-PANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKX-XXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIE 2272
            A+KH       K +   TT++EL++Y +FL+ L I+TF M   +M+Y    +++LFL T       T F S+++ +DFWKF+ GPLL GLYW+ WYN++ +      + IY+EN LLGVPR+RQ++V+NN+C + +  Q+ +++CY  Y+   E   +FG Q ++ W Y+  +   S    G +  Y  GG+   L+ S+  + N  + L  N W+ R TR + +DF++YNAN+NLFCII+LV EFP  GG+L S++F +VKL+RYV+  D+F+ +CEI F ++L  +  +E+ +I + KSAYF S+WN L++++L L  + VSF+ Y    I  +L +LL++   + +F +L+ W + Y+N+ A  +F A  KIFK+ISFNK M+QL STL+ C+KD+VGF++MFFI+F A+AQ G+L+FGSQ+ ++  F   IF  FRI+L D NF  +   NPILGP+YFI ++FFVFF+L NMFLAI++D Y ++K      +  +FE+   +K+  + V EK  LK+        A K  D    G  D  E   + +R G+ E EI+
Sbjct:   12 ASKH--KLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNT-NSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKK--------AQKDEDKKTKGSGDLAE---QARREGFDENEIQ 560          
BLAST of PKD2L-2 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012])

HSP 1 Score: 320.472 bits (820), Expect = 3.255e-97
Identity = 225/563 (39.96%), Postives = 345/563 (61.28%), Query Frame = 2
Query:  593 ATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNM-PANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKX-XXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIE 2272
            A+KH       K +   TT++EL++Y +FL+ L I+TF M   +M+Y    +++LFL T       T F S+++ +DFWKF+ GPLL GLYW+ WYN++ +      + IY+EN LLGVPR+RQ++V+NN+C + +  Q+ +++CY  Y+   E   +FG Q ++ W Y+  +   S    G +  Y  GG+   L+ S+  + N  + L  N W+ R TR + +DF++YNAN+NLFCII+LV EFP  GG+L S++F +VKL+RYV+  D+F+ +CEI F ++L  +  +E+ +I + KSAYF S+WN                       ++ +L  LL++   + +F +L+ W + Y+N+ A  +F A  KIFK+ISFNK M+QL STL+ C+KD+VGF++MFFI+F A+AQ G+L+FGSQ+ ++  F   IF  FRI+L D NF  +   NPILGP+YFI ++FFVFF+L NMFLAI++D Y ++K      +  +FE+   +K+  + V EK  LK+        A K  D    G  D  E   + +R G+ E EI+
Sbjct:   12 ASKH--KLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNT-NSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWN----------------------WLELLLLLLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKK--------AQKDEDKKTKGSGDLAE---QARREGFDENEIQ 538          
BLAST of PKD2L-2 vs. Ensembl Celegans
Match: pkd-2 (Polycystin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9U1S7])

HSP 1 Score: 265.003 bits (676), Expect = 3.633e-76
Identity = 212/630 (33.65%), Postives = 334/630 (53.02%), Query Frame = 2
Query:  791 TFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFY--VDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEII-LNA-FSMMVENSEDYRKEKIEAIIQDE 2668
             F S  +  + W +L   L+ G+YW    NS     + +N IY+EN+LLG PRIR ++V N+SC +    Q ++ +C+A Y   +E K   G  +  A+ Y     L++    G I +YGGGGF   + +A S E    I     N RW+DR +RA++VDF +YNANINLFC++KL+ E P  GGV+ + +  T  L+ Y       ++  E +F  ++LY+I EEL  I +H+  Y    WN++DV++L   V  +   + R       ++ ++ENG  +  F+ ++  +  Y N+ A ++F+A  K+FK+IS NK M+QL STL    KD+ GF++MF + F AFAQ GYL FG+Q+A+Y   Y   F L R+IL D NF  L   N   GP +FI YVFFV FIL NMFLAI++D+Y ++K EL  K++   I D+   K R +      KR K  D      T          ++++K  L R GYAE +I   F +F+      + E    K+ +++ D+  A  TE  ++R+  E           ++  Y  L+R +D ++  +  +  + + +    Q I K + + ++   ++ L+A  +  V N E   +      I D+
Sbjct:  121 AFGSCTSMDNIWDWLSQVLIPGIYWTETSNS----TDNENMIYYENRLLGEPRIRMLKVTNDSCTVMKSFQREIKECFANYEEKLEDKTMVGDGSVDAFIYATAKELENLKTVGTIASYGGGGFVQRLPVAGSTEAQSAIATLKAN-RWIDRGSRAIIVDFALYNANINLFCVVKLLFELPASGGVITTPKLMTYDLLTYQTSGGTRMMIFEGIFCGFILYFIFEELFAIGRHRLHYLTQFWNLVDVVLLGFSVATIILSVNRTKTGVNRVNSVIENGLTNAPFDDVTSSENSYLNIKACVVFVAWVKVFKFISVNKTMSQLSSTLTRSAKDIGGFAVMFAVFFFAFAQFGYLCFGTQIADYSNLYNSAFALLRLILGDFNFSALESCNRFFGPAFFIAYVFFVSFILLNMFLAIINDSYVEVKAELARKKDGEGILDWFMNKVRGL-----TKRGKRPDAPGEDAT----------YEDYKLMLYRAGYAEKDINEAFTRFNVTS---MTEHVPEKVAEDIADE-VARMTE--QKRNYME-----------NHRDYANLNRRVDQMQESVFSIVDRIEGVNATLQTIEKQRVQQQDGGNLMDLSALLTNQVRNRESAARRPTITSIADK 713          
BLAST of PKD2L-2 vs. Ensembl Celegans
Match: lov-1 (Location of vulva defective 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09624])

HSP 1 Score: 127.872 bits (320), Expect = 2.074e-29
Identity = 112/450 (24.89%), Postives = 190/450 (42.22%), Query Frame = 2
Query:  713 RPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKL---LGVPRIRQIRVKNNS-CIIPNILQNKVNQCYAAY-SRN-----------IELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLI----------RYVNPLDFF----VLACEILF-VXXXXXXXXXXXXXXDKHKSAYFCSL-----WNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKL-LENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLN 1951
            R GY +              + DN  TF S+Q   DFW +    L   L  + WY+    PA      Y  +K+   +G+  IRQ+R K ++ C +    Q  +N C     S+N            EL+   G   S  + Y     L + +  G + +Y GGG+ + ++ +Q   + +   L + RW+D +TRAV+++F+ YNA IN F +++L+ E P  G  LP+    +V+LI          +Y   L  F    +   EI+F +      I       +  K  Y  +L     WN +D+IV +L V  V  +  R       +      NGN + N      W++ +    A  +F    K+ + + FN+ +  L +TL+  L  +V F + F    + F    Y + G+++  YR       T    +L   +   + P++
Sbjct: 2699 RHGYWYQLEMSTILNINQKNYGDN--TFMSIQHADDFWDWARESLATALLAS-WYDGN--PAYGMR-AYMNDKVSRSMGIGTIRQVRTKKSAECTMFKQFQGYINDCGEELTSKNEEKTLYMQAGWTELESENGTDASDEYTYKTSEELSTETVSGLLYSYSGGGYTISMSGTQAEIITLFNKLDSERWIDDHTRAVIIEFSAYNAQINYFSVVQLLVEIPKSGIYLPNSWVESVRLIKSEGSDGTVVKYYEMLYIFFSVLIFVKEIVFYLYGRYKVITTMKPTRNPFKIVYQLALGNFSPWNFMDLIVGALAVASVLAYTIRQRTTNRAMEDFNANNGNSYINLTEQRNWEIVFSYCLAGAVFFTSCKMIRILRFNRRIGVLAATLDNALGAIVSFGIAFLFFSMTFNSVLYAVLGNKMGGYRSLMATFQTALAGMLGKLDVTSIQPIS 3142          
BLAST of PKD2L-2 vs. Ensembl Fly
Match: Pkd2 (gene:FBgn0041195 transcript:FBtr0080365)

HSP 1 Score: 218.009 bits (554), Expect = 1.819e-58
Identity = 143/388 (36.86%), Postives = 215/388 (55.41%), Query Frame = 2
Query:  902 EQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSA---YFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIK 2056
            E     +EN LLG PR+RQIRV+  SC + +      N CYAAYS   E ++       S +    D  L S      +  Y  GG+ V+L   ++ ++ II  L +  WLDR +R  LV+F ++N N ++F  IKL+ E PP GGV+P    +TVK+  +    D  +L   I    Y++          +  KS    YFCS+ N+LD  +L    + + ++I+  + + ++ ++   +   + + + L FW + Y ++ A L FL   KIFK+ISFNK + Q  +TL  C KDL GFSLMF IVFLA+AQ G L+FG++  ++R F   I T+ R+IL D  +  +   N +LGP+YF+ Y+  VFFIL NMFLAI+ + Y  +K
Sbjct:  424 EGRVFLYENLLLGPPRLRQIRVRKESCYVNDAFIRYFNTCYAAYSSGAEDRKPM--HKGSPFRTMHD--LDSTPIWTVLAFYRTGGYTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIKLIAEIPPTGGVIPQAHLQTVKMYSFFT--DRSMLMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFCSMLNILDCAILLGCYLALVYNIWHSFKVMSLTARA-HSDVTYQSLDVLCFWNIIYVDMMAILAFLVWIKIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLFGTKHPDFRNFITSILTMIRMILGDFQYNLIEQANRVLGPIYFLTYILLVFFILLNMFLAIIMETYNTVK 804          
BLAST of PKD2L-2 vs. Ensembl Fly
Match: brv3 (gene:FBgn0040333 transcript:FBtr0340092)

HSP 1 Score: 65.855 bits (159), Expect = 1.463e-10
Identity = 85/355 (23.94%), Postives = 159/355 (44.79%), Query Frame = 2
Query:  875 YNSRNMPANEQNYIYFENK-LLGVPRIRQIRVKNNSC----------------IIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVD-LATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQL----QYDNLS-AFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANY 1870
            +NS +  +    + + E   LLGV R+RQ+RV N                    +P    +  ++ +  Y   I +K  F F          D++L +    G + +Y     YV  LA S  NS+ +I  L  N WL  NT AV +DFT+YN ++NLF I  L  E  P GG++P  +  + KL+  V+ + +  L   +++VL  + +     +++  ++     S+WN LD+ +  + V+ V   + R  ++ +M+ K +E  +     E++ F +     Q   ++  FL+ +   ++++ + F  +      TL      +   ++   I  + F  A   I G+  +N+
Sbjct:  193 FNSNSTESGSPGWAHAEQSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYEPWIPIKMGFEFL---------DALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQFAQTLAVKL-WYEPHLLKSVWNKLDLFIFMVNVLVVVLVVLRESLVASMMKK-VEGAS---KMEFIDFRRPSRMHQLTTITIGFLICITTLRLWRVLQFASVFKLFTRTLYLAWSAVASTAIAIVIFLIGFCFAVVTINGNYSSNF 533          
BLAST of PKD2L-2 vs. Ensembl Fly
Match: brv3 (gene:FBgn0040333 transcript:FBtr0300708)

HSP 1 Score: 65.855 bits (159), Expect = 1.530e-10
Identity = 65/237 (27.43%), Postives = 110/237 (46.41%), Query Frame = 2
Query:  875 YNSRNMPANEQNYIYFENK-LLGVPRIRQIRVKNNSC----------------IIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVD-LATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIV 1531
            +NS +  +    + + E   LLGV R+RQ+RV N                    +P    +  ++ +  Y   I +K  F F          D++L +    G + +Y     YV  LA S  NS+ +I  L  N WL  NT AV +DFT+YN ++NLF I  L  E  P GG++P  +  + KL+  V+ + +  L   +++VL  + +     +++  ++     S+WN LD+ +
Sbjct:  193 FNSNSTESGSPGWAHAEQSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYEPWIPIKMGFEFL---------DALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQFAQTLAVKL-WYEPHLLKSVWNKLDLFI 419          
BLAST of PKD2L-2 vs. Ensembl Fly
Match: brv2 (gene:FBgn0036712 transcript:FBtr0331846)

HSP 1 Score: 52.373 bits (124), Expect = 2.394e-6
Identity = 51/206 (24.76%), Postives = 88/206 (42.72%), Query Frame = 2
Query: 1229 WLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDK-HKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQ-LQYDNL----SAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFA 1828
            WLD+NT A+ +D T+YNA+ NLF +I L  E  P G  LP     +V ++  V       L   ILFV  +L  +    +     H  A     W ++D+ +  L V      I R      +L +++E        +YL F + L+   +      FL+ +   +++K + F  +      TL    + +    ++  +V +A  
Sbjct:  297 WLDKNTSALFIDLTMYNADANLFTLITLRVENSPFGIQLPRVHVDSVSMLGNVETRSNSELL--ILFVYTVLVILFARGVFTKIWHHPAAAHEAWTMVDLAIYILNVFLTVLAIMRDIETDALL-QIIETAT---KGQYLDFQRPLRLHQMLFIVKGFLVCITTLRLWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMAIG 496          
BLAST of PKD2L-2 vs. Ensembl Fly
Match: brv2 (gene:FBgn0036712 transcript:FBtr0075242)

HSP 1 Score: 51.6026 bits (122), Expect = 3.806e-6
Identity = 51/206 (24.76%), Postives = 88/206 (42.72%), Query Frame = 2
Query: 1229 WLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDK-HKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQ-LQYDNL----SAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFA 1828
            WLD+NT A+ +D T+YNA+ NLF +I L  E  P G  LP     +V ++  V       L   ILFV  +L  +    +     H  A     W ++D+ +  L V      I R      +L +++E        +YL F + L+   +      FL+ +   +++K + F  +      TL    + +    ++  +V +A  
Sbjct:  319 WLDKNTSALFIDLTMYNADANLFTLITLRVENSPFGIQLPRVHVDSVSMLGNVETRSNSELL--ILFVYTVLVILFARGVFTKIWHHPAAAHEAWTMVDLAIYILNVFLTVLAIMRDIETDALL-QIIETAT---KGQYLDFQRPLRLHQMLFIVKGFLVCITTLRLWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMAIG 518          
BLAST of PKD2L-2 vs. Ensembl Zebrafish
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558])

HSP 1 Score: 491.886 bits (1265), Expect = 3.438e-160
Identity = 283/667 (42.43%), Postives = 428/667 (64.17%), Query Frame = 2
Query:  542 KNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQ 2542
            K   C + F   I+ LW T   ++  E+  L     ++EL++Y++FLV L ++T+ M     +Y+T  + +LF+      N  +FSS+   +D W ++ GPLL+ LYW  WYN   +    Q++IY+EN LLGVPR+RQ++VK NSC +P   + +++ C+  Y+   E   +FG  N +AW Y  +  ++  S  G +TTY G GFY DL T+++ S  ++  L  N WLDR TR + +DFT YNANINLFC+I+LV EFP  GG +PSY+ RTVKLIRYV   D+F++ CEI+F +++LYYI+EE++E   HK ++F S+WN+LD++V+ L V+ + F  +R   +  +L  LL+  +I+ +FE+L+FWQ QY+N++A  LF A  KIFKYISFNK MTQL STL  C  D+ GF++MFFIVF A+AQ GYL+FG+++  +  F  CIFT FRIIL D ++  +   N +LGP+YF  YVFFVFF+L NMFLAI++D Y ++K EL  +++EF+I D +K+   K F KL LK+EKI D++ A+ +  +     ++F +++  LK  G+++ EI + F+KFD DG++ LD+QEQ  M +EL +++ AL  EL +  ++ E   E     P     Y  L   +  LEN +  +  K D +++  +
Sbjct:   57 KKSGCCSFFFRAIKGLWGTALRKDTKENPELNVKANLKELLIYIVFLVDLCLLTYGMTSSATYYYTKAMTDLFVNLP-GSNGMSFSSIGCMNDVWTYMEGPLLDNLYWTKWYNDEPLENGNQSFIYYENLLLGVPRVRQLKVKQNSCKVPTDFKKEISDCFDVYNIKKEDDGAFGLINGTAWQYHSEKEIKGSSHWGLLTTYSGAGFYQDLTTTRDESAALLEDLRENLWLDRGTRVLFIDFTAYNANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYVTTWDYFIIGCEIVFCVFILYYIVEEILEFRIHKLSHFTSIWNILDIVVILLAVVAIVFSAFRTIKVDGLLGNLLKQPDIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLTSTLARCALDIFGFAIMFFIVFFAYAQLGYLLFGTEVETFSTFNKCIFTQFRIILGDFDYDAIDRANRVLGPIYFFSYVFFVFFVLLNMFLAIINDTYSEVKSELASQKDEFQIADLIKQSYAKTFMKLKLKKEKISDVQKALDSGASE----LEFKDFRNALKEMGHSDREISAAFSKFDQDGNQTLDKQEQENMKQELEEKRDALSAELRDLENSVEPAEEHRNTVPPE--DYQRLVHKVSQLENSVSAIMSKLDFVMEKMR 716          
BLAST of PKD2L-2 vs. Ensembl Zebrafish
Match: pkd2 (polycystic kidney disease 2 [Source:NCBI gene;Acc:432387])

HSP 1 Score: 491.5 bits (1264), Expect = 1.063e-158
Identity = 294/737 (39.89%), Postives = 466/737 (63.23%), Query Frame = 2
Query:  542 KNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETEL--IEERDNQEKLIESD--------------------AIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAF--SMMVENSEDYRKEKIEAIIQDELYK 2677
            ++ +C  +    +R LW T+     + ++ +Y  T +RE++ Y+LFL+ L IIT+ M    M+Y+T  ++ LFL T  +    T F SL    DFWKF  GP LNG+YW +WYN++++P N Q+ IY+EN LLGVPR+RQ+RV+N SC +   L+++V  CY  YS   E K  FG +N +AW + ++S L   S+ GQ++TYGGGG+Y DL+ ++E S N +  L NN WLDR TRAV +DF+IYN N+NLFCI++L+ EFP  GG +PS++F+TV+L+RYV+  D+FV  CE+ F L++LYY++EE +EI  H+  YF SLWN LDV++++L V  +  +I R   +   L  LLEN + +PNFE L+  Q+ ++NL+A ++FL+  K+FK+I+FNK M QL +T++ C KDL+GF++MFFIVFLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D +F E+   + +LGP+YF  +VFF+F IL NMFLAI++D Y ++K ++ ++ +E EITD +K+   +   KL LK+  I D+ ++++       G + FDE + +L+ +G+++ EIE++FAK+D DGD+ L E E  +M  +L  ++  L+ E   +    +      S                     +   +SY ++  L R +D +E+ I  +  K D ++   + + + K K R+    IL+       +    + ++E+++ +++DEL +
Sbjct:  121 EHRSCGKRILEKMRVLWDTRLLGESNSNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSGEPTNFKSLSTMEDFWKFTEGPFLNGMYWELWYNNKSLPEN-QSLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGPKNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQA----AGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILDGVMEDERMGRDPELQREQMDRLVRDELER 852          
BLAST of PKD2L-2 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89])

HSP 1 Score: 170.629 bits (431), Expect = 8.752e-43
Identity = 129/410 (31.46%), Postives = 214/410 (52.20%), Query Frame = 2
Query:  869 VWYNS---RNMPANEQNYIYFEN-KLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESF--GFQNS----------SAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGD 2050
            +W NS   RN+      +I   N KL+G  RIRQ+RV+ ++C I N +Q  V  C+A YS   E   S+  G+  +            W Y   + L++    G +  Y GGGF VDL   Q+N+  ++  LF+N WLD  TRAV V+FT+YNAN+NLFCI+ L+ E   VG      E + V L +       FV+A E ++ +++LYY++ +   + + K AYF S WN+L++ ++ L    +S  + R  +    +     N ++  +F   +        L AFL+ LA  K++  +  N  +  + STL     D+ GF ++  I+FLA++ A  L++G +L +YR       T+  + L   N+ E+L  NP+LG       + F+ F++ N+F++++  A+ +
Sbjct:  668 IWANSSLLRNLYGQYPGFITDGNSKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVGTFQYRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVILVAFNE 1077          
BLAST of PKD2L-2 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89])

HSP 1 Score: 169.859 bits (429), Expect = 3.401e-42
Identity = 129/410 (31.46%), Postives = 214/410 (52.20%), Query Frame = 2
Query:  869 VWYNS---RNMPANEQNYIYFEN-KLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESF--GFQNS----------SAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGD 2050
            +W NS   RN+      +I   N KL+G  RIRQ+RV+ ++C I N +Q  V  C+A YS   E   S+  G+  +            W Y   + L++    G +  Y GGGF VDL   Q+N+  ++  LF+N WLD  TRAV V+FT+YNAN+NLFCI+ L+ E   VG      E + V L +       FV+A E ++ +++LYY++ +   + + K AYF S WN+L++ ++ L    +S  + R  +    +     N ++  +F   +        L AFL+ LA  K++  +  N  +  + STL     D+ GF ++  I+FLA++ A  L++G +L +YR       T+  + L   N+ E+L  NP+LG       + F+ F++ N+F++++  A+ +
Sbjct: 2028 IWANSSLLRNLYGQYPGFITDGNSKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVGTFQYRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVILVAFNE 2437          
BLAST of PKD2L-2 vs. Ensembl Zebrafish
Match: pkd1l2b (polycystic kidney disease 1 like 2b [Source:ZFIN;Acc:ZDB-GENE-141222-87])

HSP 1 Score: 157.147 bits (396), Expect = 1.312e-38
Identity = 118/408 (28.92%), Postives = 208/408 (50.98%), Query Frame = 2
Query:  869 VWYNS---RNMPANEQNYIYFEN-KLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGF------------QNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRT----VKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAIL 2032
            VW N+   +N+      +I   N KL+G  RIRQ+RVK ++C +  ++ + V+QC   YS   E   S+G             +  +AW Y   S L++    G    Y GGG+ +DL   ++N+   +  LFN+ WLD  TRAV V+FT+YNAN++LFCI+ L+ E   VG    +++FR+    V L   V     F++A  +++ L+++YY+  +   + + K AYF + WN+LD+ ++ L    +S  I +       +    ++ N  P+F   +        + AFL+ L   K++  +  +  +  + S+L     D+   +++ FI+ LA++ A  LIFG +L  YR        +F + +   N+ E++  NP LG +     V    F++ ++F++I+
Sbjct:  571 VWANTVLLKNLFGQYPGFITDGNSKLVGNARIRQVRVKKDTCKVAKVMLHTVSQCNTPYSWGNEDMMSYGPGWEEFNSVNGSEEGITAWQYQSQSTLKALPVWGLTALYRGGGYVMDLGPDKQNATMKLQYLFNSTWLDEYTRAVFVEFTVYNANVDLFCIVTLILESSAVG----AFQFRSVLQNVSLYSSVGSFMSFLMASRVIYFLFVVYYMFLQGKLLKRQKWAYFRNKWNLLDMAIIILSWSSLSLFIQKTVQGNIDIQYYQKHKNQFPSFHDTAAVDATLRYVMAFLVLLGCVKLWHLLRLSPKLYVIASSLQRAWDDMSTLTVVIFIILLAYSLACNLIFGWELYTYRTLPDAFTAIFSLQIGIFNYDEVMNSNPALGAVIISSCVLIATFVVLSLFISII 974          
BLAST of PKD2L-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 490.345 bits (1261), Expect = 1.309e-159
Identity = 290/735 (39.46%), Postives = 465/735 (63.27%), Query Frame = 2
Query:  563 KFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPIS---------------------------YGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFS--MMVENSEDYRKEKIEAIIQDELYK 2677
            KF +G R LW T++TE     +  Y     REL+ Y++FLV++ ++T+SM    MFY+T  ++ LFL    + +  T F +L    DFWKF  GPL++GLYW++WYN+R M  N  ++IY+EN LLGVPR+RQ+RVKN SC +P  L++++  CY +YS   E    FG +N +AW YT++  L   S  G I+ Y G G+Y+DL+ ++E S   I  L NN WLDR TRAV +DF++YNAN+NLFC+++L+ EFP  GG++ S++F+TVKLI Y++  +FF+ ACEI+F +++LYYIIEE +EI  H   YF SLWN LD++++ L +  +  H+Y+M  ++  L+K L + N+ PN E L++WQ+Q+++++A ++F A  K+FK+ +FN+ MTQL +T++ C KD++GF++MFFI+FLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D +F E+   N ILGP+YF  +VFF+FFIL NMFLAI++D Y ++K ++ ++++E E+ D +K+   K   KL LK+  + D+  +++       G ++FDE + +LK +G+ + EIE++FAK+D DGD+ L E E  +M  +L  ++  LE     +R +  + +   +  P S                           Y ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+  +    +    +  +E++E ++++EL +
Sbjct:    8 KFGLGFR-LWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAEN-HSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIR----QGGGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEM----DRGSLPRPMSGRSF-PRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELER 731          
BLAST of PKD2L-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 486.108 bits (1250), Expect = 1.692e-157
Identity = 288/729 (39.51%), Postives = 462/729 (63.37%), Query Frame = 2
Query:  581 RSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPIS---------------------------YGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFS--MMVENSEDYRKEKIEAIIQDELYK 2677
            R LW T++TE     +  Y     REL+ Y++FLV++ ++T+SM    MFY+T  ++ LFL    + +  T F +L    DFWKF  GPL++GLYW++WYN+R M  N  ++IY+EN LLGVPR+RQ+RVKN SC +P  L++++  CY +YS   E    FG +N +AW YT++  L   S  G I+ Y G G+Y+DL+ ++E S   I  L NN WLDR TRAV +DF++YNAN+NLFC+++L+ EFP  GG++ S++F+TVKLI Y++  +FF+ ACEI+F +++LYYIIEE +EI  H   YF SLWN LD++++ L +  +  H+Y+M  ++  L+K L + N+ PN E L++WQ+Q+++++A ++F A  K+FK+ +FN+ MTQL +T++ C KD++GF++MFFI+FLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D +F E+   N ILGP+YF  +VFF+FFIL NMFLAI++D Y ++K ++ ++++E E+ D +K+ S K   KL LK+  + D+  +++       G ++FDE + +LK +G+ + EIE++FAK+D DGD+ L E E  +M  +L  ++  LE     +R +  + +   +  P S                           Y ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+  +    +    +  +E++E ++++EL +
Sbjct:   51 RRLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAEN-HSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKVS-KAMVKLKLKKTTVDDISESIR----QGGGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEM----DRGSLPRPMSGRSF-PRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELER 768          
BLAST of PKD2L-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 489.574 bits (1259), Expect = 3.251e-157
Identity = 287/730 (39.32%), Postives = 462/730 (63.29%), Query Frame = 2
Query:  578 IRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPIS---------------------------YGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFS--MMVENSEDYRKEKIEAIIQDELYK 2677
            +R LW T++TE     +  Y     REL+ Y++FLV++ ++T+SM    MFY+T  ++ LFL    + +  T F +L    DFWKF  GPL++GLYW++WYN+R M  N  ++IY+EN LLGVPR+RQ+RVKN SC +P  L++++  CY +YS   E    FG +N +AW YT++  L   S  G I+ Y G G+Y+DL+ ++E S   I  L NN WLDR TRAV +DF++YNAN+NLFC+++L+ EFP  GG++ S++F+TVKLI Y++  +FF+ ACEI+F +++LYYIIEE +EI  H   YF SLWN LD++++ L +  +  H+Y+M  ++  L+K L + N+ PN E L++WQ+Q+++++A ++F A  K+FK+ +FN+ MTQL +T++ C KD++GF++MFFI+FLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D +F E+   N ILGP+YF  +VFF+FFIL NMFLAI++D Y ++K ++ ++++E E+ D +K+   K   KL LK+  + D+  +++       G ++FDE + +LK +G+ + EIE++FAK+D DGD+ L E E  +M  +L  ++  LE     +R +  + +   +  P S                           Y ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+  +    +    +  +E++E ++++EL +
Sbjct:  174 VRGLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAEN-HSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIR----QGGGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEM----DRGSLPRPMSGRSF-PRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELER 893          
BLAST of PKD2L-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 485.337 bits (1248), Expect = 7.069e-156
Identity = 286/727 (39.34%), Postives = 460/727 (63.27%), Query Frame = 2
Query:  587 LWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPIS---------------------------YGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFS--MMVENSEDYRKEKIEAIIQDELYK 2677
            LW T++TE     +  Y     REL+ Y++FLV++ ++T+SM    MFY+T  ++ LFL    + +  T F +L    DFWKF  GPL++GLYW++WYN+R M  N  ++IY+EN LLGVPR+RQ+RVKN SC +P  L++++  CY +YS   E    FG +N +AW YT++  L   S  G I+ Y G G+Y+DL+ ++E S   I  L NN WLDR TRAV +DF++YNAN+NLFC+++L+ EFP  GG++ S++F+TVKLI Y++  +FF+ ACEI+F +++LYYIIEE +EI  H   YF SLWN LD++++ L +  +  H+Y+M  ++  L+K L + N+ PN E L++WQ+Q+++++A ++F A  K+FK+ +FN+ MTQL +T++ C KD++GF++MFFI+FLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D +F E+   N ILGP+YF  +VFF+FFIL NMFLAI++D Y ++K ++ ++++E E+ D +K+   K   KL LK+  + D+  +++       G ++FDE + +LK +G+ + EIE++FAK+D DGD+ L E E  +M  +L  ++  LE     +R +  + +   +  P S                           Y ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+  +    +    +  +E++E ++++EL +
Sbjct:  178 LWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAEN-HSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIR----QGGGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEM----DRGSLPRPMSGRSF-PRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELER 894          
BLAST of PKD2L-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 485.337 bits (1248), Expect = 1.350e-155
Identity = 286/728 (39.29%), Postives = 460/728 (63.19%), Query Frame = 2
Query:  584 SLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPIS---------------------------YGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFS--MMVENSEDYRKEKIEAIIQDELYK 2677
             LW T++TE     +  Y     REL+ Y++FLV++ ++T+SM    MFY+T  ++ LFL    + +  T F +L    DFWKF  GPL++GLYW++WYN+R M  N  ++IY+EN LLGVPR+RQ+RVKN SC +P  L++++  CY +YS   E    FG +N +AW YT++  L   S  G I+ Y G G+Y+DL+ ++E S   I  L NN WLDR TRAV +DF++YNAN+NLFC+++L+ EFP  GG++ S++F+TVKLI Y++  +FF+ ACEI+F +++LYYIIEE +EI  H   YF SLWN LD++++ L +  +  H+Y+M  ++  L+K L + N+ PN E L++WQ+Q+++++A ++F A  K+FK+ +FN+ MTQL +T++ C KD++GF++MFFI+FLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D +F E+   N ILGP+YF  +VFF+FFIL NMFLAI++D Y ++K ++ ++++E E+ D +K+   K   KL LK+  + D+  +++       G ++FDE + +LK +G+ + EIE++FAK+D DGD+ L E E  +M  +L  ++  LE     +R +  + +   +  P S                           Y ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+  +    +    +  +E++E ++++EL +
Sbjct:  180 GLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAEN-HSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIR----QGGGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEM----DRGSLPRPMSGRSF-PRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELER 897          
BLAST of PKD2L-2 vs. Ensembl Mouse
Match: Pkd2l1 (polycystic kidney disease 2-like 1 [Source:MGI Symbol;Acc:MGI:1352448])

HSP 1 Score: 499.204 bits (1284), Expect = 2.508e-163
Identity = 285/657 (43.38%), Postives = 438/657 (66.67%), Query Frame = 2
Query:  578 IRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETEL------IEERDNQEKLIESDAIQP-ISYGKYMGLSRHIDDLENIIEILTQKFDII 2527
            IR LW T  TEN  E++ LY  TT+RELVVY++FLV + ++T+ M     +Y+T  ++ LFL T  +D+  +F ++ + SDFW F  GPLL+ LYW  WYN++++     ++IY+EN LLG PR+RQ+RV+N+SC++    +  +  CY  YS + E +  FG QN +AW Y   + L   S  G++T+Y GGG+Y+DL  S++ S   +  L    WLDR TR V +DF++YNANINLFCI++LV EFP  GG +PS++ RTVKLIRYVN  DFF++ CE++F +++ YY++EE++EI  H+  Y  S+WN+LD++V+ L ++ V FHI+R   +  ++ KLL+  + + +FE+L+FWQ QY+N++A  LF A  KIFKYISFNK MTQL STL  C KD++GF++MFFIVF A+AQ GYL+FG+Q+ N+  F  CIFT FRIIL D ++  +   N ILGP+YF+ YVFFVFF+L NMFLAI++D Y ++KEEL  ++++ +++DFLK+   K   +L L++E++ D++  +K      +  + F+++ + L+  G+ E EI + F +FD DGD +LDE+EQ +M + L +++  L  E+      +      E   E+   Q  +S  ++  L+R +  L+ ++E +  + D +
Sbjct:   77 IRGLWGTTLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTP-SDSGVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSLGRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPQNGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLK----GGEPEIQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQGLEEERVTLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAV 728          
BLAST of PKD2L-2 vs. Ensembl Mouse
Match: Pkd2 (polycystin 2, transient receptor potential cation channel [Source:MGI Symbol;Acc:MGI:1099818])

HSP 1 Score: 473.396 bits (1217), Expect = 4.657e-151
Identity = 287/727 (39.48%), Postives = 461/727 (63.41%), Query Frame = 2
Query:  575 GIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETE------LIEERDNQEKL----------------IESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAF---SMMVENSEDYRKEKIEAIIQDELYK 2677
            G+R LW T+  E  + ++  Y  + +RELV Y+ FLV+L I+T+ M    ++Y+T  L+ LF+ T  +    T F +L +  DFWKF  G  L+GLYW     S +  A+ +++I++EN LLGVPR+RQ+RV+N SC IP  L++++ +CY  YS + E +  FG +N +AW YT +  L   S  G I +Y G G+Y+DL+ ++E +   +  L  N WLDR TRA  +DF++YNANINLFC+++L+ EFP  GGV+PS++F+ VKLIRYV   DFF+ ACEI+F  +++YY++EE++EI  H+ +YF S WN LDV+++ L V+ +  +IYRM   + +L + LE+ N  PNFE++++WQ+Q++N+SA ++FL   K+FK+I+FN+ M+QL +T++ C KDL GF++MF I+FLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D NF E+   N +LGPLYF  +VFF+FFIL NMFLAI++D+Y ++K +L +++ E E++D +++  +K   KL LKR  +  +  +++       G ++FDE + +LK +G+ + EIE++F K+D DGD+ L E+E  +M  +L  ++  L+ E       +  R     L                        +SY ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+     + +  +SE +R E++E ++++EL +
Sbjct:  194 GLRGLWGTRLMEESNANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKA-QTSNHTQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCFFIIYYVVEEILEIRIHRLSYFRSFWNCLDVVIVVLSVVAMVINIYRMSNAEGLL-QFLEDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTVDAISESLR----QGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDARLGRDSEIHR-EQMERLVREELER 913          
BLAST of PKD2L-2 vs. Ensembl Mouse
Match: Pkd2l2 (polycystic kidney disease 2-like 2 [Source:MGI Symbol;Acc:MGI:1858231])

HSP 1 Score: 356.681 bits (914), Expect = 1.091e-110
Identity = 231/560 (41.25%), Postives = 363/560 (64.82%), Query Frame = 2
Query:  638 ANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQF-NDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNM-PANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKX-XXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMD-FDE-----------WKTELKRRGYAETEIE 2272
             NTT+ EL++Y +FL+ L I+TF M   +M+Y    +++LF+ T   +D   +F S+++ ++FWKF+ GPL++GLYW+ WY ++ +      + IY+EN LLG+PR+RQ+RV+NN+C +    Q+ V+ CY+ Y+   E    FG + +  W +T  S      + G +  Y  GG+ V L+ S+  +    + L  N W+ R TRAV +DF++YNAN+NLFCII+L+ EFP  GG+L S++F +VKL+RYV+  D+F+ +CE++F ++L  +II+EL ++++ KSAYF S+WN L++++L L  + VSF+ Y       +L +LL+N + +P+F +L++W + Y+N+ A  +F A  KIFK+ISFN+ M+QL STL+ C+KD+VGF++MFFI+F A+AQ G+L+FGSQ+ ++  F   IF  FRI+L D NF  +   N ILGP+YFI ++FFVFF+L NMFLAI++D Y ++K      +  +FE+   +++    V EKL LK +     E  M+T D       D FDE           WK  L+++ Y+ TEI+
Sbjct:   25 VNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPSSRTAPWHW-GFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLRLK-KAQAKEEKKMQTTDLAQRARRDGFDESEIQEAEQMKRWKERLEKKYYS-TEIQ 581          
BLAST of PKD2L-2 vs. Ensembl Mouse
Match: Pkd2l2 (polycystic kidney disease 2-like 2 [Source:MGI Symbol;Acc:MGI:1858231])

HSP 1 Score: 356.681 bits (914), Expect = 1.091e-110
Identity = 231/560 (41.25%), Postives = 363/560 (64.82%), Query Frame = 2
Query:  638 ANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQF-NDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNM-PANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKX-XXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMD-FDE-----------WKTELKRRGYAETEIE 2272
             NTT+ EL++Y +FL+ L I+TF M   +M+Y    +++LF+ T   +D   +F S+++ ++FWKF+ GPL++GLYW+ WY ++ +      + IY+EN LLG+PR+RQ+RV+NN+C +    Q+ V+ CY+ Y+   E    FG + +  W +T  S      + G +  Y  GG+ V L+ S+  +    + L  N W+ R TRAV +DF++YNAN+NLFCII+L+ EFP  GG+L S++F +VKL+RYV+  D+F+ +CE++F ++L  +II+EL ++++ KSAYF S+WN L++++L L  + VSF+ Y       +L +LL+N + +P+F +L++W + Y+N+ A  +F A  KIFK+ISFN+ M+QL STL+ C+KD+VGF++MFFI+F A+AQ G+L+FGSQ+ ++  F   IF  FRI+L D NF  +   N ILGP+YFI ++FFVFF+L NMFLAI++D Y ++K      +  +FE+   +++    V EKL LK +     E  M+T D       D FDE           WK  L+++ Y+ TEI+
Sbjct:   25 VNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPSSRTAPWHW-GFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLRLK-KAQAKEEKKMQTTDLAQRARRDGFDESEIQEAEQMKRWKERLEKKYYS-TEIQ 581          
BLAST of PKD2L-2 vs. Ensembl Mouse
Match: Pkd1l2 (polycystic kidney disease 1 like 2 [Source:MGI Symbol;Acc:MGI:2664668])

HSP 1 Score: 179.104 bits (453), Expect = 4.223e-45
Identity = 122/408 (29.90%), Postives = 214/408 (52.45%), Query Frame = 2
Query:  872 WYNS---RNMPANEQNYIYFEN-KLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFG-------FQNSS----AWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGD 2050
            W N+   +N+  +   ++   N KL+G   IRQ+RV+ +SC +   LQ+ ++ C+  YS  IE    +G       + NS+    AW Y   S  +     G++T YGGGG+ V L T  +++  I+  LF+N WLD  TRAV V+FT+YNAN+NLFC + L  E   +G        ++++L  + +    FV+A E+ + L+L YY++ +   + K K  YFCS WN+L+V ++      +   + R  +    L +  E+ +   +F   +        + AFL+ L+  K++  +  N  M  + S L     D+ GF  +  I+ LA++ A  L+FG +L +Y+  +    T+  + L   N++E+L  +PILG L     + F+ F++ N+F++++  A+ +
Sbjct: 1995 WANTTLVKNLYGHHPGFVTDGNSKLVGSAHIRQVRVRESSCAVAQQLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLETSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHRDEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVILVAFSE 2402          
BLAST of PKD2L-2 vs. UniProt/SwissProt
Match: sp|A2A259|PK2L1_MOUSE (Polycystic kidney disease 2-like 1 protein OS=Mus musculus OX=10090 GN=Pkd2l1 PE=1 SV=1)

HSP 1 Score: 499.204 bits (1284), Expect = 1.754e-162
Identity = 285/657 (43.38%), Postives = 438/657 (66.67%), Query Frame = 2
Query:  578 IRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETEL------IEERDNQEKLIESDAIQP-ISYGKYMGLSRHIDDLENIIEILTQKFDII 2527
            IR LW T  TEN  E++ LY  TT+RELVVY++FLV + ++T+ M     +Y+T  ++ LFL T  +D+  +F ++ + SDFW F  GPLL+ LYW  WYN++++     ++IY+EN LLG PR+RQ+RV+N+SC++    +  +  CY  YS + E +  FG QN +AW Y   + L   S  G++T+Y GGG+Y+DL  S++ S   +  L    WLDR TR V +DF++YNANINLFCI++LV EFP  GG +PS++ RTVKLIRYVN  DFF++ CE++F +++ YY++EE++EI  H+  Y  S+WN+LD++V+ L ++ V FHI+R   +  ++ KLL+  + + +FE+L+FWQ QY+N++A  LF A  KIFKYISFNK MTQL STL  C KD++GF++MFFIVF A+AQ GYL+FG+Q+ N+  F  CIFT FRIIL D ++  +   N ILGP+YF+ YVFFVFF+L NMFLAI++D Y ++KEEL  ++++ +++DFLK+   K   +L L++E++ D++  +K      +  + F+++ + L+  G+ E EI + F +FD DGD +LDE+EQ +M + L +++  L  E+      +      E   E+   Q  +S  ++  L+R +  L+ ++E +  + D +
Sbjct:   77 IRGLWGTTLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTP-SDSGVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSLGRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPQNGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLK----GGEPEIQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQGLEEERVTLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAV 728          
BLAST of PKD2L-2 vs. UniProt/SwissProt
Match: sp|Q9P0L9|PK2L1_HUMAN (Polycystic kidney disease 2-like 1 protein OS=Homo sapiens OX=9606 GN=PKD2L1 PE=1 SV=1)

HSP 1 Score: 499.59 bits (1285), Expect = 4.833e-162
Identity = 291/686 (42.42%), Postives = 448/686 (65.31%), Query Frame = 2
Query:  527 QEIGFKNE--NCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAE---TEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQP--------------ISYGKYMGLSRHIDDLENIIEILTQKFDII 2527
            QE  ++ +  +C      GIR LW T  TEN  E++ LY  TT+REL+VY++FLV + ++T+ M     +Y+T  ++ LFL T  +D   +F ++ + +DFW F  GPLL+ LYW  WYN++++     ++IY+EN LLGVPR+RQ++V+N+SC++    +  +  CY  YS + E +  FG  N +AW Y     L   S  G++T+Y GGG+Y+DL  S++ S   + +L    WLDR TR V +DF++YNANINLFC+++LV EFP  GG +PS++ RTVKLIRYV+  DFF++ CE++F +++ YY++EE++E+  H+  Y  S+WN+LD++V+ L ++ V FHI+R   +  ++ KLL+  N + +FE+L+FWQ QY+N++A  LF A  KIFKYISFNK MTQL STL  C KD++GF++MFFIVF A+AQ GYL+FG+Q+ N+  F  CIFT FRIIL D ++  +   N ILGP YF+ YVFFVFF+L NMFLAI++D Y ++KEEL  +++E +++D LK+   K   +L L++E++ D++  ++      +  + F+++   L+  G+AE   TE+ + F KFD DG+R+LDE+EQ KM ++L +++ AL TE+       EKL  S    P              +S  ++  L+R +  LE ++E +  + D +
Sbjct:   58 QETAYRTQVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTP-SDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQ----GGEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEI-------EKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAV 731          
BLAST of PKD2L-2 vs. UniProt/SwissProt
Match: sp|Q6IVV8|PKD2_DANRE (Polycystin-2 OS=Danio rerio OX=7955 GN=pkd2 PE=1 SV=1)

HSP 1 Score: 491.5 bits (1264), Expect = 8.021e-158
Identity = 294/737 (39.89%), Postives = 466/737 (63.23%), Query Frame = 2
Query:  542 KNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETEL--IEERDNQEKLIESD--------------------AIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAF--SMMVENSEDYRKEKIEAIIQDELYK 2677
            ++ +C  +    +R LW T+     + ++ +Y  T +RE++ Y+LFL+ L IIT+ M    M+Y+T  ++ LFL T  +    T F SL    DFWKF  GP LNG+YW +WYN++++P N Q+ IY+EN LLGVPR+RQ+RV+N SC +   L+++V  CY  YS   E K  FG +N +AW + ++S L   S+ GQ++TYGGGG+Y DL+ ++E S N +  L NN WLDR TRAV +DF+IYN N+NLFCI++L+ EFP  GG +PS++F+TV+L+RYV+  D+FV  CE+ F L++LYY++EE +EI  H+  YF SLWN LDV++++L V  +  +I R   +   L  LLEN + +PNFE L+  Q+ ++NL+A ++FL+  K+FK+I+FNK M QL +T++ C KDL+GF++MFFIVFLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D +F E+   + +LGP+YF  +VFF+F IL NMFLAI++D Y ++K ++ ++ +E EITD +K+   +   KL LK+  I D+ ++++       G + FDE + +L+ +G+++ EIE++FAK+D DGD+ L E E  +M  +L  ++  L+ E   +    +      S                     +   +SY ++  L R +D +E+ I  +  K D ++   + + + K K R+    IL+       +    + ++E+++ +++DEL +
Sbjct:  121 EHRSCGKRILEKMRVLWDTRLLGESNSNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSGEPTNFKSLSTMEDFWKFTEGPFLNGMYWELWYNNKSLPEN-QSLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGPKNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQA----AGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILDGVMEDERMGRDPELQREQMDRLVRDELER 852          
BLAST of PKD2L-2 vs. UniProt/SwissProt
Match: sp|Q4GZT3|PKD2_BOVIN (Polycystin-2 OS=Bos taurus OX=9913 GN=PKD2 PE=2 SV=1)

HSP 1 Score: 476.863 bits (1226), Expect = 1.979e-151
Identity = 290/726 (39.94%), Postives = 456/726 (62.81%), Query Frame = 2
Query:  575 GIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALE------TELIEERDNQEKL----------------IESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFS--MMVENSEDYRKEKIEAIIQDELYK 2677
            G+R LW T+  E    D+  Y  + +REL  Y+LFL++L I+T+ M    ++Y+T  ++ LFL T  +    T F +L +  DFWKF  G LL+GLYW    ++R   A+ +++IY+EN LLGVPRIRQ+RV+N SC IP  L++++ +CY  YS + E +  FG +N +AW YT +  L   S  G I TY G G+Y+DL+ ++E +   + +L  N WLDR TRA+ +DFT+YNANINLFC+I+L+ EFP  GGV+PS++F+ VKLIRYV   DFF+ ACEI+F L++LYY++EE++EI  HK  YF S WN LDV+++ L V+ +  +IYR   ++ +L + LE+ N  PNFE L++WQ Q++N++A ++F    K+FK+I+FN+ M+QL +T++ C KDL GF++MFFI+FLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D NF E+   N +LGP+YF  +VFF+FFIL NMFLAI++D Y ++K +L +++ E E++D +++   K   KL LK+  + D+  +++       G ++FDE + +LK +G+ + EIE++F K+D DGD+ L E E  +M  +L  ++  L+         +  R     L                        +SY ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+  +    +    +  +E++E ++++EL +
Sbjct:  198 GLRGLWGTRLMEESSTDREKYLKSVLRELATYLLFLIVLCILTYGMMSSSVYYYTRIMSQLFLDTPVSKMEKTNFKTLSSMEDFWKFTEGALLDGLYWKTQPSNRT-EADNRSFIYYENLLLGVPRIRQLRVRNGSCSIPLDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGMIATYSGAGYYLDLSRTREETAAQVANLKKNVWLDRGTRAIFIDFTVYNANINLFCVIRLLIEFPATGGVIPSWQFQPVKLIRYVTTFDFFLAACEIIFCLFILYYVVEEILEIRIHKLHYFRSFWNCLDVVIIVLSVVAIGINIYRTSNVEALL-QFLEDQNTFPNFENLAYWQTQFNNIAAVIVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALIKLKLKKNTVDDISESLR----QGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEEDDDDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDNEIHREQMERLVREELER 917          
BLAST of PKD2L-2 vs. UniProt/SwissProt
Match: sp|O35245|PKD2_MOUSE (Polycystin-2 OS=Mus musculus OX=10090 GN=Pkd2 PE=1 SV=2)

HSP 1 Score: 473.396 bits (1217), Expect = 3.258e-150
Identity = 287/727 (39.48%), Postives = 461/727 (63.41%), Query Frame = 2
Query:  575 GIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETE------LIEERDNQEKL----------------IESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAF---SMMVENSEDYRKEKIEAIIQDELYK 2677
            G+R LW T+  E  + ++  Y  + +RELV Y+ FLV+L I+T+ M    ++Y+T  L+ LF+ T  +    T F +L +  DFWKF  G  L+GLYW     S +  A+ +++I++EN LLGVPR+RQ+RV+N SC IP  L++++ +CY  YS + E +  FG +N +AW YT +  L   S  G I +Y G G+Y+DL+ ++E +   +  L  N WLDR TRA  +DF++YNANINLFC+++L+ EFP  GGV+PS++F+ VKLIRYV   DFF+ ACEI+F  +++YY++EE++EI  H+ +YF S WN LDV+++ L V+ +  +IYRM   + +L + LE+ N  PNFE++++WQ+Q++N+SA ++FL   K+FK+I+FN+ M+QL +T++ C KDL GF++MF I+FLA+AQ  YL+FG+Q+ ++  F  CIFT FRIIL D NF E+   N +LGPLYF  +VFF+FFIL NMFLAI++D+Y ++K +L +++ E E++D +++  +K   KL LKR  +  +  +++       G ++FDE + +LK +G+ + EIE++F K+D DGD+ L E+E  +M  +L  ++  L+ E       +  R     L                        +SY ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+     + +  +SE +R E++E ++++EL +
Sbjct:  194 GLRGLWGTRLMEESNANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKA-QTSNHTQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCFFIIYYVVEEILEIRIHRLSYFRSFWNCLDVVIVVLSVVAMVINIYRMSNAEGLL-QFLEDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTVDAISESLR----QGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDARLGRDSEIHR-EQMERLVREELER 913          
BLAST of PKD2L-2 vs. TrEMBL
Match: A0A0H3YFR3 (PKD2L-2 OS=Schmidtea mediterranea OX=79327 GN=PKD2L-2 PE=2 SV=1)

HSP 1 Score: 1431.39 bits (3704), Expect = 0.000e+0
Identity = 785/785 (100.00%), Postives = 785/785 (100.00%), Query Frame = 2
Query:  374 MIFVYFWKITKMLNKSSVIKKNLNIVDSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQRISQY 2728
            MIFVYFWKITKMLNKSSVIKKNLNIVDSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAYGDIKEELEEKENEFEITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQRISQY
Sbjct:    1 MIFVYFWKITKMLNKSSVIKKNLNIVDSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAYGDIKEELEEKENEFEITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQRISQY 785          
BLAST of PKD2L-2 vs. TrEMBL
Match: A0A0H3YFG1 (PKD2-4 OS=Schmidtea mediterranea OX=79327 GN=PKD2-4 PE=2 SV=1)

HSP 1 Score: 685.641 bits (1768), Expect = 0.000e+0
Identity = 408/760 (53.68%), Postives = 562/760 (73.95%), Query Frame = 2
Query:  470 PCAMDGEYFDNGKITIIDYQEIGFKNEN-CWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIES-DAIQP-ISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFS--------MMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQR 2716
            P AM  + ++ GK T    +E  F N N CWN+FK GIRSLWAT+HTE+   D+ LY  TT+RELV+Y+ FL +L II+F M     ++FTN L+ LF T+ FNDNSGTF++   +SDFWKFL GPLLNGLYW  WYN+ N  +++ N++Y+EN+L+G+PR+RQ+RV+N+SC IP+  Q ++ QC+AAYS + E K+S+G QNS+ W YT  S+L +  +QG + TYGGGGFYV+L ++Q +S N I++LFNN W+DR TRAV++DFT+YNANINLFC IKLVGEFPP GG+L S +FRTVKLIRYV  +DFFVLACE+LFV++++YYI+EE +EI   K  YF S+WN+LD++V+   + C  F+I R   +Q ++  L+ N NIHPNFE L+FWQLQ+DNL A  LFLA  K+FKYISFNK MTQL +TL+ C KDL GF++MFFI+F+AFAQ GYLIFG+Q+ ++ +   CI+TLFRIIL D +F +L   + I GPLYF+ YVFFVFF+LFNMFLAI+ D YG++KEEL  ++NEFEI D++KE++  V  KLHLK++KI+D++NA+   DTNNDG MDFDEWK ELK RGY + EIE++FA++DTDGD+ LDE EQ+ M KEL DQK +L+ E+  E+   E L ++ D I P +S  +Y  L+R +D ++N   I+  K D +L+  ++I K K +SRE+  IILN  +         + +++++ +K+KI+ +I +E++KLN+   S + FQR
Sbjct:   33 PSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSYNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAVIAGDTNNDGKMDFDEWKVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEK--SEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRIIVTKIDTVLEALESIEKDKARSRETMGIILNTLNSNDDNEDYDIDDDNDEIKKKKIKELIANEIHKLNQN--SVSTFQR 788          
BLAST of PKD2L-2 vs. TrEMBL
Match: A0A0H3YJL0 (PKD2L-1 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=PKD2L-1 PE=2 SV=1)

HSP 1 Score: 651.358 bits (1679), Expect = 0.000e+0
Identity = 376/716 (52.51%), Postives = 524/716 (73.18%), Query Frame = 2
Query:  557 WNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDA----IQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRET 2692
            WN+F  G+RS+WATK TE+   ++NLY  TT+REL +Y++FL +L II F M  G M++ TN LNNLF+  Q N N+G+F+S+ + +DFW F  GPLLNGLYWN WYN+ N+  +E N+IYFENKL+G+ R+RQ+RV + SCII N  Q  + +CY  YS  IE  E FG QNS+AW YT  + L S   QG I+TYGGGG+YVDL + Q ++ +++ +LFNN W+DR TRAV+VDFT+YNANINLFC+IKL+ EFP VGGV+P Y+F+TVKL+RYV+P DFFVL CE++++++++YY +EE+IEI  HK +YF S+WN+LDV+V+ +  IC+ F+IYR   +QT+L  LL N N HPNF+YLS++Q  ++ L A  +FLA  KIFKYISFNK MTQL STL  C KDL GF++MFFI+F AFAQ GYL+FG++L  +RE +  IFTL+RIIL D  F++ L  + I GPLYF+LYVFFV F+LFNMFLAI++D Y +IK EL  ++NEFEI D+ KE+++ +  KL+LK++K+  L+NA+   DTNNDG+MDFDEWKT ++ +G+   EIES+F+++DTDG+RVLD  EQ++M  +L +QKTA+  E+I E   Q ++  S++    I  +S  +Y  L+  I+++EN+I  L  K + +L + +N+  +K K R+S   IL   S     SE+ RK KI  ++Q+EL KLN++ 
Sbjct:   45 WNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN-NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTYGGGGYYVDLPSDQFSAFSLLNNLFNNLWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTVKLLRYVSPSDFFVLGCELIYLVFIIYYTVEEIIEIKIHKISYFKSVWNILDVVVIGISFICIIFNIYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMFFIIFFAFAQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPLYFLLYVFFVLFVLFNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMLAKLNLKKDKLDVLQNALTNADTNNDGLMDFDEWKTAMQEKGFESHEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISE---QSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDNSKNKRRKSMRKILTILSSKEHLSEEERKVKIGNMVQEELIKLNQDA 756          
BLAST of PKD2L-2 vs. TrEMBL
Match: A0A267E5C4 (EF-hand domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009305g2 PE=4 SV=1)

HSP 1 Score: 632.869 bits (1631), Expect = 0.000e+0
Identity = 360/766 (47.00%), Postives = 516/766 (67.36%), Query Frame = 2
Query:  551 NCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMP-ANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEK-----------------LIESD---------AIQPISYG--------------------KYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTP 2707
             CW KFK G+R++W TK TE+  ++  L   TT+RELV+Y LFLV++ I+TF M    M+Y+T  +N+LFLTT    +  TF+S++  +D+W F  GPL++GLYW+ WYN+ N+    E+N+IY+ENKLLGVPR+RQ+RV+N+SC I    +  +  CYA YSR+ E +E FG+ NS+AWNY+ +  L    + G++ TY GGG+Y+DL  S+E S   I  LF+  W+DR TRAV +DFT+YNANINLFC+IKL+ EFP  GG   S+EFRTVKL+RYV P+D+FVLACE +F+L++ YYI+EE+IEI +HK AYF S WN LD++V+ + ++C +F+IYR   +   L++LLE+   +P+F++LSFWQ Q++   A  +F A  KIFKYISFNK MTQL STL  C KDL+GF++MFFIVF AFAQ GYLIFG+++ ++REF   IFTLFRIIL D +F  L   + +LGP+YFILYVFFVFF+L NMFLAI++D Y ++K  L  + N+FE+TD+ K+++ +V +KLHL+R+KIVD++ AM++ D NND  +DF+EW+TELK RGYA+ EIE+LFA++D DGDRVLDE+EQ KM  EL  QK AL +++  ER  Q++                 L   D         +++  + G                    ++  LSR +D +E+ I  +  + D +L   +++ + K K RE+   +L++      +SE  ++EK+E +++ EL +        TP
Sbjct:   99 GCWGKFKRGVRAVWMTKDTEDVSQNAELKIKTTLRELVMYCLFLVVICILTFGMTSSTMYYYTFVMNSLFLTTP-TASGATFTSVKNFADWWGFAQGPLISGLYWDTWYNNANVTDPRERNFIYYENKLLGVPRMRQVRVRNDSCSIATDFRANIRACYAMYSRSAESREPFGYMNSTAWNYSTEQQLDGRGYSGKLATYNGGGYYIDLGRSREESTAKIDELFHGLWIDRATRAVFIDFTVYNANINLFCVIKLIAEFPATGGGFTSWEFRTVKLLRYVEPIDYFVLACECIFMLFICYYIVEEIIEIKRHKLAYFSSFWNWLDIVVIVIALVCAAFNIYRTISVGNKLTRLLEDETQYPDFDFLSFWQEQFNQAIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLLGFAVMFFIVFFAFAQLGYLIFGTKVEDFREFQQAIFTLFRIILGDFDFASLQNAHRVLGPIYFILYVFFVFFVLINMFLAIINDTYSEVKSNLANQPNDFEMTDYFKQRAGRVLDKLHLRRDKIVDIQRAMQSADMNNDRQLDFEEWRTELKMRGYADGEIEALFARYDMDGDRVLDEEEQRKMQWELEGQKAALNSQIESERAEQQRQGSAGVGADDGDADNDELAGDDRDGAVSLRGSMRSATRGGRPNTSGSNSGGGGSGVPIDEFTTLSRRVDRMEHSIGGIVNRIDSVLLKLESMERAKLKRRETMSRLLDSIGKCEGDSEAEKREKMERMVRQELERWGGAGEEETP 863          
BLAST of PKD2L-2 vs. TrEMBL
Match: A0A267EDV5 (EF-hand domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009305g1 PE=4 SV=1)

HSP 1 Score: 629.787 bits (1623), Expect = 0.000e+0
Identity = 358/757 (47.29%), Postives = 510/757 (67.37%), Query Frame = 2
Query:  551 NCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMP-ANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEK-----------------LIESDAIQPIS------------------------------YGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYK 2677
             CW KFK G+R++W TK TE+  ++  L   TT+RELV+Y LFLV++ I+TF M    M+Y+T  +N+LFLTT    +  TF+S++  +D+W F  GPL++GLYW+ WYN+ N+    E+N+IY+ENKLLGVPR+RQ+RV+N+SC I    +  +  CYA YSR+ E +E FG+ NS+AWNY+ +  L    + G++ TY GGG+Y+DL  S+E S   I  LF+  W+DR TRAV +DFT+YNANINLFC+IKL+ EFP  GG   S+EFRTVKL+RYV P+D+FVLACE +F+L++ YYI+EE+IEI +HK AYF S WN LD++V+ + ++C +F+IYR   +   L++LLE+   +P+F++LSFWQ Q++   A  +F A  KIFKYISFNK MTQL STL  C KDL+GF++MFFIVF AFAQ GYLIFG+++ ++REF   IFTLFRIIL D +F  L   + +LGP+YFILYVFFVFF+L NMFLAI++D Y ++K  L  + N+FE+TD+ K+++ +V +KLHL+R+KIVD++ AM++ D NND  +DF+EW+TELK RGYA+ EIE+LFA++D DGDRVLDE EQ KM  EL  QK AL +++  ER  Q++                 L   D    +S                                ++  LSR +D +E+ I  +  + D +L   +++ + K K RE+   +L++      +SE  ++EK+E +++ EL +
Sbjct:   99 GCWGKFKRGVRAVWMTKDTEDVSQNAELKIKTTLRELVMYCLFLVVICILTFGMTSSTMYYYTFVMNSLFLTTP-TASGATFTSVKNFADWWGFAQGPLISGLYWDTWYNNANVTDPRERNFIYYENKLLGVPRMRQVRVRNDSCSIATDFRANIRACYAMYSRSAESREPFGYMNSTAWNYSTEQQLDGRGYSGKLATYNGGGYYIDLGRSREESTAKIDELFHGLWIDRATRAVFIDFTVYNANINLFCVIKLIAEFPATGGGFTSWEFRTVKLLRYVEPIDYFVLACECIFMLFICYYIVEEIIEIKRHKLAYFSSFWNWLDIVVIVIALVCAAFNIYRTISVGNKLTRLLEDETQYPDFDFLSFWQEQFNQAIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLLGFAVMFFIVFFAFAQLGYLIFGTKVEDFREFQQAIFTLFRIILGDFDFASLQNAHRVLGPIYFILYVFFVFFVLINMFLAIINDTYSEVKSNLANQPNDFEMTDYFKQRAGRVLDKLHLRRDKIVDIQRAMQSADMNNDRQLDFEEWRTELKMRGYADGEIEALFARYDMDGDRVLDEDEQRKMQWELEGQKAALNSQIESERAEQQRQGSAGVGADDGDADNDELAGDDRDGAVSLRGSMRSATRGGRPNTSGSNSGGGGGSGVSVDEFTTLSRRVDRMEHSIGGIVNRIDSVLLKLESMERAKLKRRETMSRLLDSIGECEGDSEAEKREKMERMVRQELER 854          
BLAST of PKD2L-2 vs. Ensembl Cavefish
Match: pkd2l1 (polycystic kidney disease 2-like 1 protein [Source:NCBI gene;Acc:103031316])

HSP 1 Score: 503.827 bits (1296), Expect = 1.688e-164
Identity = 291/687 (42.36%), Postives = 458/687 (66.67%), Query Frame = 2
Query:  542 KNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELI----------EERDNQEKLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILD--NFQNIIKTKEK 2566
            K+  C +    GI+ LW T  T++  E++ L+  TT+RELVVY++FLV + ++T+ M     +Y+T  + +LF+    +D+  TF S+    DFW +  GPLL+GLYW  WYN++++     ++IY+EN LLGVPR+RQ++VKN SC +    + +++ C+  Y+   E   SFG  N +AW Y  +  L+  +  G + TY GGG+Y DLA ++E S  ++ +L NN WLD  TRAV +DF+ YNANINLFC+I+LV EFP  GG +PSY+ RTVKLIRY+   D+F++ CEI+F +++LYYI+EE++E+  HK +YF S+WN+LDV+++ L ++ + F+++R   +  +L  LL+  +I+ +FE+L+FWQ QY+N++A  LF A  KIFKYISFNK MTQL STL  C  D++GF++MFFIVF A+AQ GYL+FG+++ ++  F+ CIFT FRIIL D ++  +   N +LGP+YF  YVFFVFF+L NMFLAI++D Y ++KEEL  ++++ +ITD +K+   K F KL LK+EKI D++  +++        ++F +++  LK  G+A+ EI + F+KFD DG+++LD++EQ  M +EL +++ AL  EL           +E D+ EK   ++++  ++  ++  L + + +LE  +     K D++++    Q+  KT +K
Sbjct:   84 KSSGCCSFLLRGIKGLWGTTLTKDTTENRELFVRTTLRELVVYIVFLVDMCLLTYGMTSSTTYYYTKVMTDLFVNAP-SDSGVTFQSIGTMDDFWSYAQGPLLDGLYWTSWYNNQSLQTGTHSFIYYENMLLGVPRVRQLKVKNKSCKVHKDFEEEISDCFDVYNEKKEDDSSFGLINGTAWQYHTEKELKGSNHWGMLATYSGGGYYQDLALTKEESAGVLANLNNNLWLDHGTRAVFIDFSTYNANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYITTWDYFIIGCEIVFCVFILYYIVEEILELRIHKLSYFKSIWNILDVVIIMLAIVAIVFNVFRTIKVDKLLGNLLKEPSIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCATDILGFAIMFFIVFFAYAQLGYLLFGTEVESFSTFHKCIFTQFRIILGDFDYDGIERANRVLGPIYFFTYVFFVFFVLLNMFLAIINDTYSEVKEELASQKDDLQITDLIKQSYSKTFMKLKLKKEKISDVQKVLRSGSKE----LEFKDFRETLKEMGHADHEISAAFSKFDYDGNQILDKEEQETMKQELEEKRDALSVELHNLGINYEKNGKETDDNEK---TNSVL-VTAQQFQMLVKQVVELECSLATTMAKIDVVMEKLGLQDAGKTNKK 761          
BLAST of PKD2L-2 vs. Ensembl Cavefish
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:103043751])

HSP 1 Score: 498.819 bits (1283), Expect = 1.391e-161
Identity = 292/741 (39.41%), Postives = 465/741 (62.75%), Query Frame = 2
Query:  548 ENCWNKFKIG-IRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYM-FYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQ--------------------------PISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAF---SMMVENSEDYRKEKIEAIIQDELYK 2677
            ++ W K  +  +R LW T+  E+ +  + +Y    +RE V Y+ FL+ L IIT+ M    M FY          T     +  TF +L    DFWK+  GP LNG+YW+VWYN++++P N Q+ IY+EN LLGVPR+RQ++V N SC +   L+++V  CY+ YS   E K  FG +N++AW Y+E++IL   S+ G++ TY GGG+Y DLA S+E S   +  L +N WLDR TRAV +DF++YN N+NLFCI++++ EFP  GG + S++F+TV+L+RYV+  D+FV  CE++F L++LYY++EE++EI  H+  YF SLWN LDVI+++L    +  +IYR   +   L  LLEN + +PNF+ L+  Q+Q+++L+A ++FLA  K+FK+I+FNK M+QL +T++ C KDL+GF++MFFIVFLA+AQ  YL+FG+QL ++  F  CIFT FRIIL D +F E+   N +LGP+YF  +VFF+F IL NMFLAI++D Y ++K ++ ++ +E EITD +K+  +K   KL L++  + D+ ++++       G ++FDE + +L+ +G+++ EIE++FAK+D DGD+ L E E  +M  +L  ++  L+     ER +  + +   +                             +SY ++  L R +D +E+ I  +  K D ++   + + + K K RE    +L+       M  ++E +R E +E ++++EL +
Sbjct:  125 QHGWGKRILAKLRILWGTRLMEDSESSREVYLKNVLRETVTYIFFLITLCIITYGMVSTNMYFYTKVMSQLFLDTPLSKGDPTTFKTLSTMEDFWKYTEGPFLNGMYWDVWYNNKSLPEN-QSLIYYENLLLGVPRLRQVKVLNKSCPVHEDLKDEVYDCYSIYSPASEDKAPFGLKNNTAWVYSEENILGESSYWGEVATYRGGGYYQDLARSREESARQLKELKDNLWLDRGTRAVFLDFSVYNGNVNLFCIVRMLVEFPATGGAVTSWQFQTVRLVRYVSSWDYFVGTCEVVFCLFVLYYMVEEVLEIRLHRLRYFKSLWNCLDVIIVTLSAPAIIMNIYRTSAVSNRLRYLLENHSTYPNFQPLAQVQVQFNHLAAVIVFLAWVKLFKFINFNKTMSQLSTTMSRCAKDLLGFAIMFFIVFLAYAQLAYLVFGNQLNDFSTFQACIFTQFRIILGDFDFSEIEETNRVLGPIYFTTFVFFMFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKGYQKAMVKLRLRKTTVDDISDSLRQA----GGKLNFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELSEHEHQQMKDDLEKEREDLDL----ERSSLPRPMSGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVMEDERMGRDTEVHR-EHMEKLVREELER 855          
BLAST of PKD2L-2 vs. Ensembl Cavefish
Match: pkd1l2a (polycystin 1 like 2 [Source:NCBI gene;Acc:103044173])

HSP 1 Score: 174.866 bits (442), Expect = 7.204e-44
Identity = 132/415 (31.81%), Postives = 225/415 (54.22%), Query Frame = 2
Query:  872 WYNSR---NMPANEQNYIYFEN-KLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQ-NSS-----------AWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLS-KLLENGNIHPNFEYLSFWQLQYDN-----LSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGD 2050
            W NS    N+   +  +I   N KL+G  R+RQ+RV++ SC +   ++N V  C+A YS ++E   S+G   N S            W Y   S L++    G +  Y GGGF VDL  ++EN+ + +  LF N WLD  TRA+ V+FT+YNAN+NLFCI+ L+ E   VG      E ++V+L +    L  FV+A E+++ L++ YY+ ++   + + K  YF S WN+LD     + +I +S+    +++ +T+L  + +E    H + EY  F +    +     + AFL+ LA  K++  +  N  +  + STL     D+ GF ++  I+FLA++ A  L++G +L +YR       T+  + L   N++E+L  NP+LG       + F+ F++ N+F++++  A+ +
Sbjct: 2142 WANSTLLNNLFGQQPGFITDGNSKLVGNARLRQVRVQDGSCRVDRSMRNSVPDCHAPYSWDMEDLGSYGPGWNPSIDANLSKTLPTPWQYQTQSRLRAHPIWGGVAVYRGGGFVVDLGPNRENASSSLQYLFENTWLDMFTRAIFVEFTVYNANVNLFCIVTLMFETTAVGAFQYRSELQSVRLYQSTGGLHIFVMASEVVYFLFIFYYMFQQGKLMKQQKWEYFRSKWNLLD-----MAIIILSWSALPVFIKRTLLGNQSIEYYQNHKD-EYAGFNETATADAVLGYIIAFLVLLATVKLWHLLRLNPKLHMITSTLQRAWNDISGFIVVMTIMFLAYSVACNLLYGWKLYSYRTLLNAAQTIVSLQLGIFNYEEVLDYNPVLGAFIVGSCIIFMTFVVLNLFISVILVAFSE 2550          
BLAST of PKD2L-2 vs. Ensembl Cavefish
Match: ENSAMXT00000006495.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:35007331:35041448:1 gene:ENSAMXG00000006274.2 transcript:ENSAMXT00000006495.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 158.303 bits (399), Expect = 9.538e-39
Identity = 121/409 (29.58%), Postives = 211/409 (51.59%), Query Frame = 2
Query:  869 VWYNSR---NMPANEQNYIYFEN-KLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSS------------AWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYG 2047
            +W NS    N+      +I   N KL+G  R+RQ+RV+ +SC   + +++ V  C+A YS  +E   S+G   +S             W Y   S L++ +  G +  Y GGGF VDL   Q+NS +++  LF N WLD  TRA+ ++FT+YNAN+NLFCI+ L+ E   VG      E + ++L +  + +    L  E ++ L++LYY+  +   + + K  YF + WN+L++ ++ L     S  I +M      L    ++ N  P+F   +        L+A L+ LA  K++  +  N  +  + +TL     D+  F ++  I+FLA++    L+FG +L  Y+        +  + L   N++E+L LNP+LG       + F+ F++ N+F++++ +A+ 
Sbjct: 1260 IWANSSLLTNLFGQYSGFITDGNSKLVGTARLRQVRVQKSSCRKASSVRSSVPDCHAPYSWEVEDMGSYGPGWTSLIDSNMSKALFTPWQYQTQSRLRAHTVWGGMALYRGGGFVVDLEPDQQNSSSVLQYLFENAWLDIYTRALFIEFTVYNANVNLFCIVTLMLETTAVGAFQYRTELQNIRLFQTTDGIP--TLVSEAIYFLFILYYMFLQAKLMKQQKWEYFRNKWNILELAIILLSWSAFSVFIKKMVQGDQDLKYYQDHRNQFPSFYETAAADSVLGYLTAVLVLLATIKMWHLMRLNSKLNMITNTLQQAWSDISSFIVVIVIMFLAYSIVSNLLFGWKLYTYKTLIDAATAMVSLQLGIFNYEEILDLNPVLGAFIIGSCIIFMTFVVLNLFISVILEAFS 1666          
BLAST of PKD2L-2 vs. Ensembl Cavefish
Match: pkd1a (polycystic kidney disease 1a [Source:ZFIN;Acc:ZDB-GENE-100707-1])

HSP 1 Score: 55.0694 bits (131), Expect = 4.538e-7
Identity = 60/241 (24.90%), Postives = 112/241 (46.47%), Query Frame = 2
Query: 1154 GGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKL--IRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANY 1870
            GGF  +L+   E+S ++I  L +++W    TRA+ V+F++YN N +L  +  L+ EFP       S + +T  L  + +   L  F+    ++F++Y             +   +YF  +WN+  +  L L  +  + H+ R  +   + +  L+      +F  L+        L+A LLFL + K    + F +       TL   + +L+  +L   ++ LA++  G+L+F S L  Y
Sbjct: 3727 GGFVQELSRRMEDSRSLIQQLLSHQW----TRALFVEFSLYNTNTDLLAVFTLLLEFPVSERAQSSLDLKTCSLHTLHHGLDLSLFLTLLLMIFIIYFSVREGVAA---HRQGRSYFLRVWNLAGMCTLLLAAVVSALHLSRSALATRLWASFLQQRESFTDFFPLAQQNQVLTQLNATLLFLLVLKASHQLRFLREWAVFGRTLRRSVWELLAAALALLVLLLAYSHMGHLLFHSVLEGY 3960          
BLAST of PKD2L-2 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558])

HSP 1 Score: 478.404 bits (1230), Expect = 1.710e-157
Identity = 280/659 (42.49%), Postives = 423/659 (64.19%), Query Frame = 2
Query:  569 KIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGT-FSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTAL--ETELIEERDNQEKLIESDAIQPISYGKYMG----LSRHIDDLENIIEILTQKFDI 2524
            ++     W T+ TE  +  +  Y  TT+REL++Y++FL+ L ++TF M     +Y+T  + +LF+ +  +   GT F+S+ +  DFWK + GP+L+GLYW  WYN   +P N  ++I +EN +LGVPR+RQ++V+N SC I  + +N +  CY  YS   E KE+FG    +AW Y  +  L   S  G +  Y G G+Y DL+  +  S  ++  L +  WLD  TRAV +DFT YN NINLFC+++LV EFP  GG LPSY+FRTVKLIRYV+  D+F++ACE++F  ++LYY++EE +E+  H   YF S+WN LD+IV+ L ++ + F+I R   +  +L  LL + NI+ +FEYL+FWQ Q++N+ A  +F A  KIFKY+SFNK +TQL STL  C KD++GF++MFFI+F A+AQ GYL+FGSQ+ ++  F  CIFT FRIIL D +F  +   N ILGP+YF  Y+FFVFF+L NMFLAI++D Y D+K EL + +++FEI DF K+  + +  KL +K++ I D++ A+ +   +    +++D W+  L R G+++ EI + F+KFD D D VLDE EQ ++  EL  QK  L  + E ++  DN  K  ++  +    + ++      +   +D L + +E L  K ++
Sbjct:    5 RVCCPGFWGTRLTE-VNSTREQYFKTTLRELIIYVVFLIDLCLLTFGMMNTNTYYYTKVMMDLFVESPVSPIDGTNFNSISSMDDFWKVVQGPVLDGLYWEKWYNGDQLPVN-LSFIQYENVMLGVPRVRQLKVRNGSCTIYPLFRNIIPGCYDGYSCGEEDKETFGRGTGTAWKYWSEEELSGSSHWGLLAQYSGAGYYRDLSRRKNESAPMLQELKDYLWLDHGTRAVFIDFTTYNGNINLFCVVRLVVEFPLTGGALPSYQFRTVKLIRYVSAFDYFIMACEVIFCCFILYYVVEECLELRLHGMKYFKSVWNCLDIIVIVLSMVAIIFNICRTIAVSNLLGALLNDPNIYADFEYLAFWQTQFNNMLAINVFFAWIKIFKYVSFNKTLTQLSSTLARCAKDVLGFAVMFFIIFFAYAQTGYLVFGSQVEDFSSFVNCIFTQFRIILGDFDFHAIENANRILGPIYFTTYIFFVFFVLLNMFLAIINDTYTDVKAELADTKDDFEIGDFFKQGYKNMLNKLKMKKDDIADMQRALDSAGKH----LEYDIWRKNLIRLGHSDEEIAAAFSKFDKDSDNVLDEDEQKQLRAELEGQKDKLNEDIEALKTMDNSGKPGDASRVTKDDFNRFASRVAKMESSMDSLMSKVESLLTKLEM 657          
BLAST of PKD2L-2 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558])

HSP 1 Score: 469.929 bits (1208), Expect = 8.970e-153
Identity = 296/685 (43.21%), Postives = 423/685 (61.75%), Query Frame = 2
Query:  578 IRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMF-YXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXX--XXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQK------------TALETELIEERDNQEKLIE-----------SDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIK 2554
            +R LW T+ TE+   D++ Y  TT+REL VY+ FL+ L I+TF M    M+ Y     N     T   ++S  F+S+    DFWK + GP+LNGLYW  WYN   +  N Q++IY+EN LLGVPRIRQ++V+N+SC +    Q  V  CYAAYS + E K SFG    + W Y+  S +   S  G + TY GGG+Y+DL  S+  S  ++  LF+ +WLDR TRA+L+DF+ YN NINLF +I+L+ EFPP GG +PS +  TVKLIRYV   D+F+LACE +F  ++LYYI+EE++E+  HK AYF S+WN LD++V+ L V+ + F++YR   +  +L  LL+  N + NF++L+FWQ QY+N+ A  +F    K FKY+SFNK MTQL STL  C KD++GF++MFFI+F A+AQ GYL+FG+Q+ ++  F  CIFT FRIIL D +F  +   N +LGPLYF  YVF V    +  NMFLAI++D Y ++K EL EKENEF++  + K+    + +KL   R  IVD+   +  +D ++  + ++D+W+ +LKR G+++ EIE+ FAKFD D + VLD  E   M  EL  QK              L   +    D   K I            +D I  + Y  Y  L +++D+LE  I  +  K D+I++   ++ K
Sbjct:   94 LRGLWGTRLTEDI-TDRDKYVKTTLRELFVYIAFLINLIILTFGMTSDLMYKYTLAMDNLFLQNTVSPNDSVNFNSIFTFDDFWKVVQGPVLNGLYWEKWYNDIPLVEN-QSFIYYENFLLGVPRIRQLKVRNDSCTVHADFQKDVQGCYAAYSEDAEDKASFGPATGTPWKYSTSSDMNGSSHWGLLATYSGGGYYLDLTRSKSESAILLQDLFDKQWLDRGTRAILIDFSSYNGNINLFSVIRLLVEFPPTGGAVPSSQIYTVKLIRYVTGSDYFILACEGIFCCFILYYIVEEILELSIHKFAYFKSVWNCLDLLVIMLSVVAIIFNVYRTVTVNKLLKALLDEPNRYGNFQFLAFWQTQYNNMVAVNVFFCWIKFFKYVSFNKTMTQLSSTLARCAKDVLGFAVMFFIIFFAYAQLGYLLFGTQVEDFSTFSNCIFTQFRIILGDFDFNAIENANRVLGPLYFTTYVFVVFFVLLPKNMFLAIINDTYAEVKNELAEKENEFDVGGYFKKVYLDIRKKLGKNRGNIVDM---ISVLDASSQKI-NYDDWRLKLKRLGHSDEEIEAAFAKFDKDKNSVLDSNEMKLMRDELKSQKKDGSMDRVLSPCVLLNYVIFRNLDCSAKCINNLSGEINHRRYADDISTL-YNVYKRLVQNVDNLEQSISTMFSKVDVIMNKVGSLAK 771          
BLAST of PKD2L-2 vs. Ensembl Sea Lamprey
Match: pkd2 (polycystic kidney disease 2 [Source:NCBI gene;Acc:432387])

HSP 1 Score: 244.588 bits (623), Expect = 2.136e-69
Identity = 201/739 (27.20%), Postives = 364/739 (49.26%), Query Frame = 2
Query:  587 LWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMR-PGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWK----FLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSC-IIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDL-ATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXX-XXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIH-PNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETEL-IEERDNQEK----------------LIESDAIQPISYG-------------KYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENS---EDYRKEKIEAIIQDELYK 2677
            LWAT+ TE+   ++  Y    +RE V + +FL LL ++ +S R P    Y          +   N +  TF +L      W+    +L GPLL  L+ +    SRN+     + +  EN ++    I Q RV NNSC  +   L     +CY  YS   E K+ FG  NS+ W +  ++ +    +QG +  YG GG+ V L A S+  +   + +L +  WLDR TR + VD  + N N+ L+ +++L  EFPP GG+L +      + +    PL      C +L  L  + Y + E L   +   + +  S W  LD+ +++L V+  +F ++   +  ++L +   +  +       ++ W+  +  ++  ++F+A  K+ ++ S  + +T     L  C  DL+G++L+F  VFLAFAQ  +LIFG  L ++  F  CI T  RI+L D +F  L   + I+GP+YF+ YVF V  I+  MFLAI+ +AY + K E    + +F+++  +K+   KV ++L  K+ ++  ++  +        G ++F  W+  LK +G+A+ EIE++FA++D DG   L   EQL+M ++L  +K  +   + +  R+ ++K                  E D I  +  G             ++  L R ++ +E+ I  +  K D ++   + + + + + R+    +++        S   ++ R++ +E +++DEL +
Sbjct:    2 LWATRWTESPVLNRERYVKLAIREAVTFSVFLALLCVVAYSSRIPLAYEYTHAVSEMFTSSPLSNADPTTFHNLATIEQVWQVFHGYLTGPLLWALHNS---GSRNL---TNSMVSGENLVVEPVIIWQARVHNNSCWSLSTNLGTGTTECYGPYSSANENKDPFGPANSTVWRFDSEAGV---PWQGALGWYGPGGYAVRLPADSRTAAWQELAALRDASWLDRATRLLSVDAALLNPNLRLYMVVRLSMEFPPTGGILTALSLTPGRPLG--TPLWDARAVCGLLAALLTIYYLVEEVLELRNLGPAGFLSSPWTFLDISIIALCVVGTAFGVHHGILSSSLLGEASSSRAMSFSTVSTVAEWEQNFIIVTGVIVFVAWIKVVRFGSMCRTLTMCGCALTRCAWDLLGYTLVFATVFLAFAQLAFLIFGGALPDFSSFSSCILTQVRILLGDFDFSSLEAASRIMGPIYFVSYVFCVGLIMMVMFLAIVSEAYSEEKSEQAHSQPQFQLSSVIKQV--KVVDRLSCKKPRVAGIQKTLPP-----SGQINFATWRQNLKGQGFADAEIEAVFARYDGDG--ALTRAEQLQMRRDLRLEKQTIRLHISVSPREKKKKHQVTSRDDDDDDDDGDSDEDDDITVVRRGNHHQGGGGGVSREEFRVLVRRVNQMEHSIGSVVSKMDAVMVKLEAMERQRLRRRDVLSRLISGMGEEERGSWPGQEVRRDHMERLVRDELKR 720          
BLAST of PKD2L-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007306.1 (pep scaffold:Pmarinus_7.0:GL480012:400827:419749:1 gene:ENSPMAG00000006595.1 transcript:ENSPMAT00000007306.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 136.346 bits (342), Expect = 7.486e-33
Identity = 109/410 (26.59%), Postives = 183/410 (44.63%), Query Frame = 2
Query:  845 LLNGLYWNVWYNSRNMPANEQNYIY-FENKLLGVPRIRQIRVKNNS----CIIPNILQNKVNQCYAAYSR-NIELKESFGFQNSSAWNYT--EDSILQ-SGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTV-KLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAY 2044
             L   Y   WYN   M   E+ Y+  F    +G  R+RQIR    +       P  +       Y   +R N    E    +  +   Y      + Q    +   +  Y GGGF  +L  +  +   I+ +L +  WLD +TRAVL +FT YN N +LFC + L+ EF    G    + +  V ++  +V  L+       I+F + L+     E + + +   AYF S WN+ +++ ++LG   V  +  +M +    L K   + +   NF+ L  W  Q   L A L+F++  K+  ++   +    L+   +     + GF+++  +VF +F Q   L+F   L NYR F  C+  LF ++L    + EL   N +LGPL +  +     F++ N  L IL + +
Sbjct:  658 FLPNFYPRAWYNGERMSWRERYYLRDFSTIRVGPGRLRQIRSVPRAWNLLLSAPTAVATLSRAPYVVAARANQRCGEGTTQRKRAVRQYQIFSHRVTQLVPVWHPSLALYSGGGFIAELGLNLADGTEIVANLSSASWLDHSTRAVLTEFTGYNMNTDLFCSVTLLLEFSQGAGDAHGHAYIHVFRIESFVGKLETLTGVVYIVFAILLVIIAATEALRLSELGVAYFKSFWNIAELLSITLGAASVVTYFIKMSVATRTLEKFRTDPHKFVNFQELVTWDQQLSELLATLVFVSTIKVLGHMKSLRQFEVLVGAFSEARDHIQGFAVIVVVVFCSFGQLTSLLFAGSLRNYRTFTTCLEQLFSLLLGQPGYGELYAANRVLGPLIYFAFTSVNTFVIVNFSLGILSEGF 1067          
BLAST of PKD2L-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002645.1 (pep scaffold:Pmarinus_7.0:GL476683:134:12081:-1 gene:ENSPMAG00000002415.1 transcript:ENSPMAT00000002645.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.0182 bits (175), Expect = 1.219e-13
Identity = 70/318 (22.01%), Postives = 144/318 (45.28%), Query Frame = 2
Query: 1130 GQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVL--ACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNI--HPNFEYLSFWQLQYDN---------LSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAY 2044
            G++ T+ G G+  DL  +   +   +  L  N W+D  T  +   F IYNAN NLFC+++++ E        PS   +  +L    N + + +L     I +++  +Y++   +  I K K  Y     NV +++ ++L             MI  ++ ++  +  +  H NF +L  +   Y +             +LFLA  +I     +N  M++ ++   +C   L  FSL+FF++ ++++   + + G+++  YR F   + +LF  +     F +L      +  L +  ++     +L NM + ++++ Y
Sbjct:    1 GELNTFIGSGYIADLGLTFAEASGNMSYLEQNSWVDARTTGLYAQFIIYNANANLFCLVEVLVESLSADMFQPSSNLKVFRLFN--NRISYIILDNVAYIFYLIISMYFLTCVIFSITKEKFEYLKKPMNVAEIMNITL-------------MIMKLIKQVSRSPALGSHLNFFFLINYCTLYSHKPLILLSTQFLGLVLFLATLRILPLFRYNTTMSEAVTLAAHCAHKLCSFSLIFFVLLISYSLIFWNVLGTRVGAYRSFGKSVGSLFAALHGAPVFGDLYAAGGYMAALLYFSFMLLFTVLLLNMMVVVIEEVY 303          
BLAST of PKD2L-2 vs. Ensembl Nematostella
Match: EDO47023 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN85])

HSP 1 Score: 571.237 bits (1471), Expect = 0.000e+0
Identity = 350/790 (44.30%), Postives = 507/790 (64.18%), Query Frame = 2
Query:  461 DNAPCAMDGEYFDNGKITIIDYQEIGFKNE--NCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNM--PANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQ---------------------------------------PISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAF--SMMVENSEDYRK-EKIEAIIQDELYKLNRET 2692
            D  P AM+ E   + K    D +  G KN    CW +FK  IR LW T+ TE+ D D+ ++  TT+REL++Y++F+ +L I+TF M    M+YFT  + +LF+ +  + N  TF  +   ++FW +    L +GLYW  +YN++N+  P ++  +IYFENK+LG PR RQ+RV N+SC + +  ++ + +CYAAYS N+E   +FG  N SAW Y  +  LQ  S+ G++TTY GGGF   LA ++  +  II  L  N WLDR TRAV +DFT+YNANINLFCI++LV E+PP GG +PS+ FRTVKLIRYV+  D FV+ACE +F+L+++YY IEE +EI KHK  YF S WNVLDV+V+ LG + V F++YR   +  +LS LLE+G+ + NF+ L FWQ Q++N+ A  +F A  K+FKYISFNK MTQL STL+ C KD+ GF++MFFI+F A+AQ GYLIFG+Q+ ++  F   IFTLFRIIL D +F ++   N +LGPL+F+ YVFFVFF+L NMFLAI++D Y ++K ++  +E+EFEITD+ K+  + +  KL  KREKI+D++ A+K+ D N D  +DF+EW+  LK RG+A+ EIE++FAK+D DGDR+LDE EQ +M ++L  QK  L  E IEE + Q++     A +                                        +SY ++  LSR +D +E+ I  +  K D +L   + + K K K RE+   +L++   S     SED +K E++E ++++EL + + E 
Sbjct:   51 DVMPSAMEAEPVSHQKRIAADVRVPGAKNVPVGCWTRFKRIIRGLWRTRQTEDTDSDREMHIKTTLRELIIYLVFITILCILTFGMTSSTMYYFTKVMRDLFVESSMS-NRNTFKDITTMNEFWMYTTETLSDGLYWEQYYNNQNVTKPKDDLGFIYFENKILGRPRFRQLRVLNDSCTVHDDFKSVIKECYAAYSPNVEDMNTFGKMNGSAWTYQTEKDLQGRSYWGRMTTYSGGGFTQLLAPTKAETQQIIEDLKQNLWLDRGTRAVFIDFTVYNANINLFCIVRLVFEYPPTGGCIPSFNFRTVKLIRYVDTFDHFVMACEGIFILFIIYYTIEEGLEIKKHKMKYFKSFWNVLDVVVIMLGYVAVVFNLYRTMAVGDLLSSLLEDGSQYANFDSLGFWQTQFNNMVAVAVFFAWIKVFKYISFNKTMTQLSSTLSKCAKDVAGFAIMFFIIFFAYAQLGYLIFGTQVRDFSTFEDSIFTLFRIILGDFDFHQIENANRVLGPLFFMTYVFFVFFVLLNMFLAIINDTYAEVKSDIASQESEFEITDYFKKGYQNMLNKLSFKREKILDIQKALKSADVNQDNKLDFEEWRANLKSRGHADAEIEAVFAKYDLDGDRILDEDEQRRMQEDLEGQKAELNDE-IEEMERQKESRPKSASRMSFRGSDADSDDDDDDSQGGLSGRVGSAAGHRRGGGGGGGVSYEEFNVLSRRVDRMEHSIGSIVSKIDAVLVKLEAMEKAKLKRRETMAKLLDSITESDRSGRSEDEKKREQMERMVREELERWDSEA 838          
BLAST of PKD2L-2 vs. Ensembl Nematostella
Match: EDO44884 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUD7])

HSP 1 Score: 186.037 bits (471), Expect = 3.009e-48
Identity = 141/459 (30.72%), Postives = 237/459 (51.63%), Query Frame = 2
Query:  791 TFSSLQAQSDFWKFLMGPLLNGLYWNVWYN-SRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQ------------NSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVF 2128
            TF  +   S+ W +    LL  LY   WY  ++  P   +        ++G  R RQ+R K ++C+I  +++  ++ C   YS + + + ++  +             S+ W++   S L    + G+I+TY GGG+ V  ++    ++  I    NN W+DR T  +  +FT+YN   NLF    ++ E  P GG     EF T +L   V     F L C+++F+L+  Y+   EL ++ K K +YF   WN  +++++ L  I V+ +   + + +  L    EN N + NF+Y+S WQ+ ++++   L+F++  K  K + FNK M  L  TL+   KDL  + +MF IVFL+FAQ  YL+ GS   ++  F   I  L  ++L   +F+E L    I+G   F LY+    F+L NMF+AI+ +++ ++K   E   NEFEI +F  E+ R+V 
Sbjct:  604 TFQKISNDSEIWLWTNHVLLPALYNLDWYYYTKTAPKLVRGG---AGLVVGFARWRQLRKKKDTCLITGVMRGVIHHCTDPYSMSTQDETNYNSRWRPFNTSDVPPSPSTIWSFNSASKLNGYPYFGEISTYSGGGYIVPFSSIYYKAVKEIKHARNNSWIDRYTAGLFTEFTLYNPYSNLFTASTVLVEVLPTGGFHVRPEFFTFRLYSLVGDFHIFTLVCDVVFLLFTSYFTFRELKKLYKDKCSYFRDYWNWAEIVIMVLAWIAVADYFICLGIRKWTLKLHQENPNDYTNFQYISAWQMSFESILGILVFISTIKFIKLLRFNKKMFLLAYTLSRSAKDLAHYGIMFLIVFLSFAQFYYLLLGSDYDSFSTFVKSIEKLINVLLGRFSFEEFLIPFRIMGAFGFFLYMTLTNFLLLNMFIAIIVESFTEVKLSPELARNEFEIMEFTVERVREVL 1059          
BLAST of PKD2L-2 vs. Ensembl Nematostella
Match: EDO44744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUR6])

HSP 1 Score: 184.111 bits (466), Expect = 1.821e-47
Identity = 136/448 (30.36%), Postives = 233/448 (52.01%), Query Frame = 2
Query:  815 SDFWKFLMGPLLNGLYWNVWYNSR-NMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESF---GFQNSS--------AWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAY-FCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSR 2119
            + FW +    L+ GLY   WYN R + P    ++  +   +LG  R+RQ+RVK   C + ++    + QC   YS + E        G++ +         AW Y + S L+S  + G++  Y GGG+  DL   +E ++ ++  L  ++W+DR+TRA+ V+FT+Y+   NL C+  L+ E  P GG  P  E    ++ RY      FVL CEILFVL+ +Y+  ++  EI +   AY F   W+ +++++       +  +  R  + ++ +    ++ ++  NF  L+     +  + AF+ F    K  +   FNK M+ L +TL    K+L  FS++F +VF+AF    YLIF ++L  +      + TL  ++L   +++ LL  N +L P  F  Y   V FIL NMF++I+ + +  +K + + + NE+EI DF+ E+ R
Sbjct:  671 TSFWNWTEAVLIPGLYSESWYNGRSDKPGFLADHTSW---MLGTARMRQLRVKAGDCKVHDVYSGYLAQCNGPYSWDTEDTTPVFRPGWRPAPSNYSTAQNAWKYRDSSELRSLPYLGKLALYSGGGYAFDLG-KKEKAMAMLAQLKRDKWVDRSTRAIFVEFTVYSPYTNLHCVGYLLLEVLPSGGTSPFSELLVTRIDRYAGNFMIFVLLCEILFVLFTVYFTYKQGKEIAREGVAYHFHEYWSWVELVLSGCSWTSIVLYFVRFGINKSTVLTYHKDTSVFVNFHALAASDQVFGYVYAFVAFFVSLKFLRLFRFNKRMSLLATTLKCSAKELAHFSIVFGLVFMAFVHFCYLIFSTELYIFHTVLSTVETLISVMLGKFSYERLLQTNRLLAPFMFFFYSIVVVFILINMFISIIIENFQRVKSQNDLQSNEYEIVDFMTEQFR 1114          
BLAST of PKD2L-2 vs. Ensembl Nematostella
Match: EDO49200 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHB8])

HSP 1 Score: 177.948 bits (450), Expect = 1.399e-45
Identity = 131/422 (31.04%), Postives = 215/422 (50.95%), Query Frame = 2
Query:  824 WKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFE-NKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYS------RNIELKESFGFQNSSAWNYTEDSILQSGSFQ----GQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIK 2056
            W +    L+  LY    YN +  P     Y+    N L+G+ R+R  RVKN SC IP  +    ++CY  +S       + E++  F  ++++       SI +  SF     G++  Y GGG+  DL      +L ++  L ++ W++ NTR V ++F IYNAN NLF +  L  EF P GG  P  EF+  +L  YV P   FVLA E++ +L++ Y++  E+  + K K  YF   WN L+V ++ L  + +     RM+ +     +L  N     +F+Y        + +   L+F    +  K + FN+ M  L +T+    K +  F + F +VF++FA  G +IFG  L  +R F   + T   I L D ++ E+   N +LG +YF  +++F+   L NMFLAI++D++ ++K
Sbjct:  679 WHWARETLIKNLYPGNLYNGK--PDKYTGYLEDRVNYLVGISRLRLERVKNGSCTIPKEMDRFFDECYGEFSYSNSDSDDYEVEWMFLNKSAAPSARKRRSIAEQFSFGFPYWGKMNFYSGGGYPADLGYDYPTALTVVADLHSHNWVNSNTRGVFIEFAIYNANTNLFGVAFLYVEFLPTGGAFPHGEFKVARLYSYVGPFANFVLAMEVIMLLFMFYFVYREVKSMYKLKKKYFKGFWNWLEVAMIVLEFLMLGLFFARMWEVDKNFIELHHNPKDFVSFQYALASDETLNYVIGILVFFVTIRFIKLLRFNRRMALLGNTIALIAKPIGQFLISFTLVFISFAFFGNMIFGIGLDKFRSFTTTMMTQLNICLGDFDYLEMEEENRMLGRIYFFSFMYFIVMYLMNMFLAIINDSFSEVK 1098          
BLAST of PKD2L-2 vs. Ensembl Nematostella
Match: EDO40051 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8E5])

HSP 1 Score: 168.703 bits (426), Expect = 1.079e-44
Identity = 127/453 (28.04%), Postives = 230/453 (50.77%), Query Frame = 2
Query:  779 DNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENK----LLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESF--GFQNS-SAWNYTEDSILQSGSFQGQITTYGGGG----FYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFL 2104
            + S  F  + +  D+W +L   ++  ++   WYN ++         Y  +     +L V R+RQ+R++ ++C +   LQ+ +  C   YS + E +     G++   +AW Y     L++  + GQ  TY  GG    F    A + + +  +  +L  N WLD+ TRAV  +F+IYNAN NLFC++ L+ E  P GG+       T++L RYV    FFV ACEI+++L+  Y+I  E+ +  K       + W++L++ V  L +  V  +  R+     ++  +  +     +  Y +F       L   ++F +  KI + + FN+ M+ L  TL  C+  +  F +++ I F A+AQ   L+FG     +        TL   +L     KE+  +N ++GP +F +Y   + FIL NMF++I++D++ ++  ++ ++ N++EI DF+
Sbjct:   51 NGSTKFDEIGSTRDYWPWLKDTVIPSIFIEKWYNDQDYHLG-----YLADTPTAWVLAVARLRQLRMQKHTCPLLPALQHVIPSCNDFYSSDEEERGMLLPGWKEPKTAWQYQTGEELKTFPYWGQKATYSAGGYVQVFPPSTAKNYDKAQALADALNENDWLDKYTRAVFTEFSIYNANSNLFCVVTLLIEQLPTGGIFKFPSILTLRLYRYVGGEMFFVAACEIIYLLFTAYFIFREIKQAYKLGLDKLKNPWSILEIFVTCLSLSMVVLYFLRIKFTAEVVKDMRNDPTRFVSLHYTAFLDEWIKCLMGLIVFFSFIKIVRLLRFNRRMSLLAQTLKLCIPKIGAFVIVYGIAFFAYAQLACLVFGQNAEGFMTIPRSAATLMDTLLGKFTLKEMSDINRLIGPTFFYIYTLSMIFILINMFMSIINDSFAEVNSDVSKQANDYEIVDFM 498          
BLAST of PKD2L-2 vs. Ensembl Medaka
Match: pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel [Source:NCBI gene;Acc:100820724])

HSP 1 Score: 504.212 bits (1297), Expect = 7.966e-165
Identity = 301/717 (41.98%), Postives = 461/717 (64.30%), Query Frame = 2
Query:  464 NAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEK-LIESDAIQP-----------ISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRES 2578
            ++P ++D      GK      Q +  K+  C   F   I+ LW T  TEN   ++  Y  TT+REL+VY+LFL+ + ++T+ M     +YFT  + +LF+ +   D    F S+   +DFW F  GPLL+GLYW  WYN +++    Q++IY+EN LLGVPR+RQI++KNNSC +    ++++  CY  Y    E   +FG  N +AW Y  +  ++  S  G ++TY G G+Y DL  ++E S  I+ +L +N WL R TR V +DF+ YNANIN+FC+I L+ EFP  GG +PSY+ RTVKL+RYV   D+F+L CE +F +++LYY++EE++E+  H+ +Y  S+WN+LD++V+ L ++ ++F+++R   +  +L KLLEN NI+ +FE+L+FWQ QY+N++A  LF A  KIFKYISFNK MTQL +TL  C KD++GF++MFFIVF A+AQ GYL+FG+++  +  F  CIFT FRIIL D NF  +   N +LGP+YF+ YVFFVFF+L NMFLAI++D Y ++KEEL  +++E +ITD +K+   K F +L LK++KI D++ A++       G + F ++K  L   G+ + EI + F+KFD DG++VLD +EQ +M +EL +++ AL TEL     N EK  +E+++  P           +   ++  L+R +  ++  +  +T + ++IL   Q  ++ K K  ES
Sbjct:   57 DSPYSLDAA----GKFPEASVQRVKKKSGCC--SF---IKGLWGTALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSG-GDAGVAFQSIGTMADFWSFAQGPLLDGLYWTKWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGLINGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTVKLLRYVTRWDYFILGCEAVFCVFILYYMVEEVLELRIHRFSYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQA----GSGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTELNHLGKNYEKEPVETESFPPHEQRSVSNQTFVDQQQFQSLARQVLQVQRSVADITSRMELILA--QMGLQEKAKGGES 757          
BLAST of PKD2L-2 vs. Ensembl Medaka
Match: pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel [Source:NCBI gene;Acc:100820724])

HSP 1 Score: 501.516 bits (1290), Expect = 3.606e-162
Identity = 301/717 (41.98%), Postives = 461/717 (64.30%), Query Frame = 2
Query:  464 NAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEK-LIESDAIQP-----------ISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRES 2578
            ++P ++D      GK      Q +  K+  C   F   I+ LW T  TEN   ++  Y  TT+REL+VY+LFL+ + ++T+ M     +YFT  + +LF+ +   D    F S+   +DFW F  GPLL+GLYW  WYN +++    Q++IY+EN LLGVPR+RQI++KNNSC +    ++++  CY  Y    E   +FG  N +AW Y  +  ++  S  G ++TY G G+Y DL  ++E S  I+ +L +N WL R TR V +DF+ YNANIN+FC+I L+ EFP  GG +PSY+ RTVKL+RYV   D+F+L CE +F +++LYY++EE++E+  H+ +Y  S+WN+LD++V+ L ++ ++F+++R   +  +L KLLEN NI+ +FE+L+FWQ QY+N++A  LF A  KIFKYISFNK MTQL +TL  C KD++GF++MFFIVF A+AQ GYL+FG+++  +  F  CIFT FRIIL D NF  +   N +LGP+YF+ YVFFVFF+L NMFLAI++D Y ++KEEL  +++E +ITD +K+   K F +L LK++KI D++ A++       G + F ++K  L   G+ + EI + F+KFD DG++VLD +EQ +M +EL +++ AL TEL     N EK  +E+++  P           +   ++  L+R +  ++  +  +T + ++IL   Q  ++ K K  ES
Sbjct:   57 DSPYSLDAA----GKFPEASVQRVKKKSGCC--SF---IKGLWGTALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSG-GDAGVAFQSIGTMADFWSFAQGPLLDGLYWTKWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGLINGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTVKLLRYVTRWDYFILGCEAVFCVFILYYMVEEVLELRIHRFSYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQA----GSGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTELNHLGKNYEKEPVETESFPPHEQRSVSNQTFVDQQQFQSLARQVLQVQRSVADITSRMELILA--QMGLQEKAKGGES 757          
BLAST of PKD2L-2 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346])

HSP 1 Score: 472.626 bits (1215), Expect = 1.282e-151
Identity = 284/747 (38.02%), Postives = 461/747 (61.71%), Query Frame = 2
Query:  512 TIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFN-DNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETE---LIEERDNQE-------------------KLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAF--SMMVENSEDYRKEKIEAIIQDELYK 2677
            T+   Q+   ++  C  +    IR LW T+  E+ D ++  Y    +REL+ Y+ FL+ + I+T+ M    M+Y+T  ++ LFL    + +N  TF SL    DFWK+  GP L G+YW VWYN++++P N Q++IY+EN LLGVPR+RQ+RV N +C I   L+++V  CY  Y+ + E    FG QN +AW +T +S + + +  GQ++ YGGGG+Y DL+ ++E S   +  L ++ WLDR TRA+ +DF++YN N+NL CI +L+ EFP  GGVL S++F+TV+LI+YV+  D+FV  CE+ F L++LYY++EE++EI  H+  YF +LWN LDV++++L V+ +   I R  M   +L K LEN   H +F+ L+  Q+Q++N++A ++F    K+FK+I+FNK M+QL +T++ C KDLVGF++MFFI+FLA+AQ  YL+FG+Q+ ++  F   +FT FRIIL D +F E+   NP+LGP+YFI +V F+FFIL NMFLAI++D Y ++K ++ +  +E E+TDF+K+   K   KL LK+  + D+ ++++       G +++DE   +LK +G+ E EI+++FAK+D DGD  L E +  +M  +L  ++  L+ E   L      +                          +   +SY ++  L R +D +E+ I  +  K D ++   + + + K K R+    +L+       +    D  +E++E ++++EL +
Sbjct:  117 TLNGQQQDRHEHPGCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGN-QSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLL-KGLENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQA----GGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELER 857          
BLAST of PKD2L-2 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346])

HSP 1 Score: 473.396 bits (1217), Expect = 2.681e-151
Identity = 286/761 (37.58%), Postives = 465/761 (61.10%), Query Frame = 2
Query:  512 TIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFN-DNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETE---LIEERDNQE-------------------KLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAF--SMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQRI 2719
            T+   Q+   ++  C  +    IR LW T+  E+ D ++  Y    +REL+ Y+ FL+ + I+T+ M    M+Y+T  ++ LFL    + +N  TF SL    DFWK+  GP L G+YW VWYN++++P N Q++IY+EN LLGVPR+RQ+RV N +C I   L+++V  CY  Y+ + E    FG QN +AW +T +S + + +  GQ++ YGGGG+Y DL+ ++E S   +  L ++ WLDR TRA+ +DF++YN N+NL CI +L+ EFP  GGVL S++F+TV+LI+YV+  D+FV  CE+ F L++LYY++EE++EI  H+  YF +LWN LDV++++L V+ +   I R  M   +L K LEN   H +F+ L+  Q+Q++N++A ++F    K+FK+I+FNK M+QL +T++ C KDLVGF++MFFI+FLA+AQ  YL+FG+Q+ ++  F   +FT FRIIL D +F E+   NP+LGP+YFI +V F+FFIL NMFLAI++D Y ++K ++ +  +E E+TDF+K+   K   KL LK+  + D+ ++++       G +++DE   +LK +G+ E EI+++FAK+D DGD  L E +  +M  +L  ++  L+ E   L      +                          +   +SY ++  L R +D +E+ I  +  K D ++   + + + K K R+    +L+       +    D  +E++E ++++EL +   +  +     RI
Sbjct:  117 TLNGQQQDRHEHPGCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGN-QSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLL-KGLENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQA----GGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELERWETDDVASQSAMRI 871          
BLAST of PKD2L-2 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346])

HSP 1 Score: 414.461 bits (1064), Expect = 1.114e-129
Identity = 258/747 (34.54%), Postives = 433/747 (57.97%), Query Frame = 2
Query:  512 TIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFN-DNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETE---LIEERDNQE-------------------KLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAF--SMMVENSEDYRKEKIEAIIQDELYK 2677
            T+   Q+   ++  C  +    IR LW T+  E+ D ++  Y    +REL+ Y+ FL+ + I+T+ M    M+Y+T  ++ LFL    + +N  TF SL    DFWK+  GP L G+YW VWYN++++P N Q++IY+EN LLGVPR+RQ+RV N +C I   L+++V  CY  Y+ + E    FG QN +AW +T +S + + +  GQ++ YGGGG+Y DL+ ++E S   +  L ++ WLDR TRA+ +DF++YN N+NL CI +L+ EFP  GGVL S++F+TV+LI+YV+  D+FV  CE+ F L++LYY++EE++EI  H+  YF +LWN LDV++++L V+ +   I R  M   +L K LEN   H +F+ L+  Q+Q++N++A ++F    K+FK+I+FNK M+QL +T++ C KDLVGF++MFFI+FLA+AQ  YL+FG+Q+ ++  F   + +   ++ N             L PL+F+           ++F          +K ++ +  +E E+TDF+K+   K   KL LK+  + D+ ++++       G +++DE   +LK +G+ E EI+++FAK+D DGD  L E +  +M  +L  ++  L+ E   L      +                          +   +SY ++  L R +D +E+ I  +  K D ++   + + + K K R+    +L+       +    D  +E++E ++++EL +
Sbjct:  117 TLNGQQQDRHEHPGCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGN-QSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLL-KGLENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSV-SRTDLLYN-------------LRPLHFLYSHGEKGICTVSLF----------VKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQA----GGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELER 833          
BLAST of PKD2L-2 vs. Planmine SMEST
Match: SMESG000018504.1 (SMESG000018504.1)

HSP 1 Score: 1397.88 bits (3617), Expect = 0.000e+0
Identity = 759/781 (97.18%), Postives = 761/781 (97.44%), Query Frame = 2
Query:  374 MIFVYFWKITKMLNKSSVIKKNLNIVDSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQR 2716
            MIFVYFW+ITKMLNKSSV+KKNLNI DSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY                 DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISY KYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQ 
Sbjct:    1 MIFVYFWQITKMLNKSSVLKKNLNIADSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQE 764          
BLAST of PKD2L-2 vs. Planmine SMEST
Match: SMESG000018504.1 (SMESG000018504.1)

HSP 1 Score: 1377.46 bits (3564), Expect = 0.000e+0
Identity = 749/769 (97.40%), Postives = 750/769 (97.53%), Query Frame = 2
Query:  407 MLNKSSVIKKNLNIVDSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQ 2713
            MLNKSSV+KKNLNI DSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY                 DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISY KYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQ
Sbjct:    1 MLNKSSVLKKNLNIADSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQ 752          
BLAST of PKD2L-2 vs. Planmine SMEST
Match: SMESG000018504.1 (SMESG000018504.1)

HSP 1 Score: 1329.69 bits (3440), Expect = 0.000e+0
Identity = 727/745 (97.58%), Postives = 727/745 (97.58%), Query Frame = 2
Query:  479 MDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQ 2713
            MDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY                 DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISY KYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQ
Sbjct:    1 MDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQ 728          
BLAST of PKD2L-2 vs. Planmine SMEST
Match: SMESG000018492.1 (SMESG000018492.1)

HSP 1 Score: 683.715 bits (1763), Expect = 0.000e+0
Identity = 406/760 (53.42%), Postives = 562/760 (73.95%), Query Frame = 2
Query:  470 PCAMDGEYFDNGKITIIDYQEIGFKNEN-CWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIES-DAIQP-ISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFS--------MMVENSEDYRKEKIEAIIQDELYKLNRETYSCTPFQR 2716
            P AM  + ++ GK T    +E  F N N CWN+FK GIRSLWAT+HTE+   D+ LY  TT+RELV+Y+ FL +L II+F M     ++FTN L+ LF T+ FNDNSGTF++   +SDFWKFL GPLLNGLYW  WYN+ N  +++ N++Y+EN+L+G+PR+RQ+RV+N+SC IP+  Q ++ QC+AAYS + E K+S+G QNS+ W YT  S+L +  +QG + TYGGGGFYV+L ++Q +S N I++LFNN W+DR TRAV++DFT+YNANINLFC IKLVGEFPP GG+L S +FRTVKLIRYV  +DFFVLACE+LFV++++YYI+EE +EI   K  YF S+WN+LD++V+   + C  F+I R   +Q ++  L+ N NIHPNFE L+FWQLQ+DNL A  LFLA  K+FKYISFNK MTQL +TL+ C KDL GF++MFFI+F+AFAQ GYLIFG+Q+ ++ +   CI+TLFRIIL D +F +L   + I GPLYF+ YVFFVFF+LFNMFLAI+ D YG++KEEL  ++NEFEI D++KE++  V  KLHLK++KI+D++NA+   DTNNDG MDFDEW+ ELK RGY + EIE++FA++DTDGD+ LDE EQ+ M KEL DQK +L+ E+  E+   E L ++ D I P +S  +Y  L+R +D ++N   ++  K D +L+  ++I K K +SRE+  IILN  +         + +++++ +K+KI+ +I +E++KLN+   S + FQR
Sbjct:   13 PSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSFNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAVLAGDTNNDGKMDFDEWRVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEK--SEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRVIVTKIDTVLEALESIEKDKARSRETMGIILNTLNSNDNNEDYDIDDDNDEIKKKKIKELIANEIHKLNQN--SVSTFQR 768          
BLAST of PKD2L-2 vs. Planmine SMEST
Match: SMESG000033381.1 (SMESG000033381.1)

HSP 1 Score: 494.967 bits (1273), Expect = 6.755e-162
Identity = 311/744 (41.80%), Postives = 455/744 (61.16%), Query Frame = 2
Query:  461 DNAPCAMDGEY-FDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVREXXXXXXXXXXXXIITFSMRPGYMFYXXXXXXXXXXXXQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQEXXXXXXXXXXXXRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVXXXXXXXXXXXXXXDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLXXXXXXXXXXXXXXNMFLAILDDAYGDIKXXXXXXXXXXXITDFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERD-NQEKLIESDAIQP-ISYGKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLN 2683
            DN P AM+ ++  +N   T    +E  + +  CW KFK  +RSLWATK TE+  E++ LY  TTVREL++Y++FL +L II F M     FY+T  L  LFL  +F+D   +F+++   S+ W++L GP LNGLYW+ WYN +++  ++ + +Y+EN++LG+PRIRQ++V+NNSC IP + Q  +  CY+ +S   E K +FG  NS+AW YT    L S  +    + Y  GGFY DL+ ++  +L ++ SLF N W+   TR + +DFT+YN NINLF +++L+ EFP +GGV  S EFR VKL+RY++  D+F+ ACE++F L+++YYI+EE IEI KHK AYF   WN LD++V+ + ++C  F IYR   +Q ++  LL N N  P F++LS+ Q Q++N  A  LF+A  KIFKYISFNK MTQL STL    KDL GF++MFFI+F AFA+ GY IFGSQ+ ++        T FRIIL D ++++L   + I+GP                            +K E+  ++NEFE+ D+ +  +R V + L  K++KI D+++A+   D N+D  +D+DEW+ ELK RGYA+ EIES+F K+D DGDR L+  EQ  +  ELN +K  +E ++ E +  N E    SD  +  I   +Y  L R +D +E  I  +  K D +L NF  + K K    +    +L A +      ED R+ +I  II  EL K N
Sbjct:   28 DNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDI-TDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFIVYYIVEETIEIRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLFGFAVMFFIIFFAFAELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGP----------------------------VKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQKNLEGELNIEKELIEKDIEETKQFNGEN---SDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYN 739          
The following BLAST results are available for this feature:
BLAST of PKD2L-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PKD2L11.007e-16242.42polycystin 2 like 1, transient receptor potential ... [more]
PKD28.356e-14639.61polycystin 2, transient receptor potential cation ... [more]
PKD2L21.624e-10541.39polycystin 2 like 2, transient receptor potential ... [more]
PKD2L22.175e-10541.39polycystin 2 like 2, transient receptor potential ... [more]
PKD2L23.255e-9739.96polycystin 2 like 2, transient receptor potential ... [more]
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BLAST of PKD2L-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pkd-23.633e-7633.65Polycystin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9U... [more]
lov-12.074e-2924.89Location of vulva defective 1 [Source:UniProtKB/S... [more]
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BLAST of PKD2L-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pkd21.819e-5836.86gene:FBgn0041195 transcript:FBtr0080365[more]
brv31.463e-1023.94gene:FBgn0040333 transcript:FBtr0340092[more]
brv31.530e-1027.43gene:FBgn0040333 transcript:FBtr0300708[more]
brv22.394e-624.76gene:FBgn0036712 transcript:FBtr0331846[more]
brv23.806e-624.76gene:FBgn0036712 transcript:FBtr0075242[more]
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BLAST of PKD2L-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkd2l13.438e-16042.43polycystic kidney disease 2-like 1 [Source:ZFIN;Ac... [more]
pkd21.063e-15839.89polycystic kidney disease 2 [Source:NCBI gene;Acc:... [more]
pkd1l2a8.752e-4331.46polycystic kidney disease 1 like 2a [Source:ZFIN;A... [more]
pkd1l2a3.401e-4231.46polycystic kidney disease 1 like 2a [Source:ZFIN;A... [more]
pkd1l2b1.312e-3828.92polycystic kidney disease 1 like 2b [Source:ZFIN;A... [more]
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BLAST of PKD2L-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
usp331.309e-15939.46ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
usp331.692e-15739.51ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
usp333.251e-15739.32ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
usp337.069e-15639.34ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
usp331.350e-15539.29ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
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BLAST of PKD2L-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pkd2l12.508e-16343.38polycystic kidney disease 2-like 1 [Source:MGI Sym... [more]
Pkd24.657e-15139.48polycystin 2, transient receptor potential cation ... [more]
Pkd2l21.091e-11041.25polycystic kidney disease 2-like 2 [Source:MGI Sym... [more]
Pkd2l21.091e-11041.25polycystic kidney disease 2-like 2 [Source:MGI Sym... [more]
Pkd1l24.223e-4529.90polycystic kidney disease 1 like 2 [Source:MGI Sym... [more]
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BLAST of PKD2L-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A2A259|PK2L1_MOUSE1.754e-16243.38Polycystic kidney disease 2-like 1 protein OS=Mus ... [more]
sp|Q9P0L9|PK2L1_HUMAN4.833e-16242.42Polycystic kidney disease 2-like 1 protein OS=Homo... [more]
sp|Q6IVV8|PKD2_DANRE8.021e-15839.89Polycystin-2 OS=Danio rerio OX=7955 GN=pkd2 PE=1 S... [more]
sp|Q4GZT3|PKD2_BOVIN1.979e-15139.94Polycystin-2 OS=Bos taurus OX=9913 GN=PKD2 PE=2 SV... [more]
sp|O35245|PKD2_MOUSE3.258e-15039.48Polycystin-2 OS=Mus musculus OX=10090 GN=Pkd2 PE=1... [more]
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BLAST of PKD2L-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YFR30.000e+0100.00PKD2L-2 OS=Schmidtea mediterranea OX=79327 GN=PKD2... [more]
A0A0H3YFG10.000e+053.68PKD2-4 OS=Schmidtea mediterranea OX=79327 GN=PKD2-... [more]
A0A0H3YJL00.000e+052.51PKD2L-1 (Fragment) OS=Schmidtea mediterranea OX=79... [more]
A0A267E5C40.000e+047.00EF-hand domain-containing protein OS=Macrostomum l... [more]
A0A267EDV50.000e+047.29EF-hand domain-containing protein OS=Macrostomum l... [more]
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BLAST of PKD2L-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkd2l11.688e-16442.36polycystic kidney disease 2-like 1 protein [Source... [more]
pkd21.391e-16139.41polycystin 2, transient receptor potential cation ... [more]
pkd1l2a7.204e-4431.81polycystin 1 like 2 [Source:NCBI gene;Acc:10304417... [more]
ENSAMXT00000006495.29.538e-3929.58pep primary_assembly:Astyanax_mexicanus-2.0:5:3500... [more]
pkd1a4.538e-724.90polycystic kidney disease 1a [Source:ZFIN;Acc:ZDB-... [more]
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BLAST of PKD2L-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkd2l11.710e-15742.49polycystic kidney disease 2-like 1 [Source:ZFIN;Ac... [more]
pkd2l18.970e-15343.21polycystic kidney disease 2-like 1 [Source:ZFIN;Ac... [more]
pkd22.136e-6927.20polycystic kidney disease 2 [Source:NCBI gene;Acc:... [more]
ENSPMAT00000007306.17.486e-3326.59pep scaffold:Pmarinus_7.0:GL480012:400827:419749:1... [more]
ENSPMAT00000002645.11.219e-1322.01pep scaffold:Pmarinus_7.0:GL476683:134:12081:-1 ge... [more]
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BLAST of PKD2L-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of PKD2L-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO470230.000e+044.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448843.009e-4830.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO447441.821e-4730.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO492001.399e-4531.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO400511.079e-4428.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of PKD2L-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkd2l17.966e-16541.98polycystin 2 like 1, transient receptor potential ... [more]
pkd2l13.606e-16241.98polycystin 2 like 1, transient receptor potential ... [more]
pkd21.282e-15138.02polycystin 2, transient receptor potential cation ... [more]
pkd22.681e-15137.58polycystin 2, transient receptor potential cation ... [more]
pkd21.114e-12934.54polycystin 2, transient receptor potential cation ... [more]
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BLAST of PKD2L-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000018504.10.000e+097.18SMESG000018504.1[more]
SMESG000018504.10.000e+097.40SMESG000018504.1[more]
SMESG000018504.10.000e+097.58SMESG000018504.1[more]
SMESG000018492.10.000e+053.42SMESG000018492.1[more]
SMESG000033381.16.755e-16241.80SMESG000033381.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30033924
GenBankAKN21732.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033924 ID=SMED30033924|Name=PKD2L-2|organism=Schmidtea mediterranea sexual|type=transcript|length=2945bp
AGACTCGTCATTGTATGACAAGGGATTAATACAAACGTTTATGGTTAAAG
TTCTGTAAGAGCTTTTTGAAAATATAAAAATATTTTATTGAATCTTATTT
GTAATATTTATTATTAATTTTACTATTTACTTATATATTTTTTAATAAAA
ATATAATATATCGTATCGACATTGTGGGTCGAATTCAACCGCACTTTGGG
AACCCCTGATTTACATGAATAATTAAATTTAGTTACTAAATGGACATTTT
TCTTTAAACAACATATATTTTAAGTTCATAGCATTAACAACTTGGATAAA
ATTACATAATCATCATTACGTAATATAAATTGTTAACGTCCTGATACCAT
GACAATTATTAAATATCTTTAAAATGATTTTTGTATATTTCTGGAAGATT
ACCAAGATGTTAAACAAATCATCCGTAATAAAAAAAAACCTAAACATAGT
AGACAGTCATGATAATGCGCCTTGCGCTATGGATGGAGAATATTTCGATA
ATGGAAAAATAACAATAATTGATTATCAAGAGATTGGATTCAAAAATGAA
AATTGTTGGAATAAATTTAAAATTGGAATTCGATCACTTTGGGCTACAAA
ACATACTGAAAACTGCGATGAAGATAAGAACCTTTATGCAAATACAACAG
TTCGGGAGTTAGTTGTTTACATGCTATTTCTGGTTTTATTGTTCATTATT
ACATTTTCAATGAGACCTGGATATATGTTTTACTTCACCAATTTTTTAAA
CAACCTATTTTTAACTACTCAATTTAATGATAATTCTGGAACATTTTCTT
CTCTTCAAGCTCAGTCAGACTTTTGGAAATTTTTGATGGGTCCATTGTTA
AACGGCCTATATTGGAATGTTTGGTACAATAGTAGAAATATGCCAGCTAA
TGAACAAAATTATATTTATTTCGAAAACAAATTGCTTGGTGTTCCAAGAA
TAAGACAAATTCGCGTGAAGAATAATTCATGTATTATACCGAATATACTT
CAGAATAAAGTAAATCAATGTTATGCAGCTTATTCTAGAAATATAGAATT
AAAAGAATCTTTTGGTTTTCAAAATTCTTCAGCTTGGAATTATACAGAAG
ACTCCATTTTGCAATCAGGTAGTTTTCAAGGTCAGATTACTACATATGGT
GGTGGTGGATTCTACGTAGATTTGGCAACATCCCAAGAAAACTCTTTAAA
TATAATTTTATCTTTATTTAACAATCGGTGGCTGGATCGAAATACTAGAG
CAGTATTAGTTGATTTTACAATTTACAATGCAAATATCAATTTGTTTTGT
ATTATAAAATTGGTTGGTGAATTTCCACCAGTAGGTGGGGTATTACCTTC
TTATGAGTTTCGAACAGTAAAATTGATTCGATACGTCAATCCATTGGATT
TTTTCGTTTTGGCATGTGAAATATTATTTGTACTTTATCTACTGTACTAC
ATAATCGAAGAACTTATTGAAATAGATAAACATAAATCTGCTTACTTCTG
TTCATTGTGGAATGTGTTGGATGTTATCGTGCTATCACTAGGTGTTATTT
GTGTTAGCTTTCACATTTACAGAATGTATATGATCCAAACAATGTTATCA
AAACTATTAGAAAATGGAAATATTCATCCAAATTTCGAATATCTAAGCTT
TTGGCAATTGCAATATGATAATTTATCAGCGTTCCTTTTGTTTTTAGCAA
TTACCAAGATTTTCAAATACATCAGTTTTAACAAAATGATGACTCAATTG
ATTTCTACCTTGAATTATTGCTTGAAAGATTTAGTCGGATTTTCTTTGAT
GTTTTTTATTGTATTTCTTGCTTTTGCACAAGCTGGTTATTTAATTTTTG
GCTCGCAGTTGGCAAATTATCGAGAGTTCTACATATGCATATTTACATTA
TTTCGAATTATTCTGAATGATTGTAATTTCAAAGAATTGCTGCCTCTGAA
TCCAATTCTTGGACCCTTATATTTTATTTTATATGTTTTCTTTGTATTTT
TCATTTTATTCAATATGTTTTTGGCAATACTTGATGATGCATATGGTGAT
ATTAAAGAGGAATTAGAAGAAAAAGAAAATGAGTTTGAAATAACAGATTT
TCTTAAAGAAAAAAGTCGCAAAGTCTTTGAAAAGCTCCATTTGAAAAGAG
AAAAAATTGTTGATCTTGAAAATGCAATGAAGACTGTGGACACCAATAAT
GATGGTGTAATGGACTTCGATGAATGGAAAACCGAATTAAAAAGAAGAGG
GTATGCTGAAACGGAAATCGAATCATTATTTGCCAAATTTGATACTGACG
GGGATAGAGTATTAGATGAACAAGAACAACTTAAAATGCTAAAAGAATTG
AATGATCAAAAAACAGCTTTAGAAACTGAACTGATTGAGGAAAGAGATAA
TCAAGAAAAACTTATTGAAAGTGATGCAATTCAACCAATATCGTATGGCA
AATATATGGGATTATCTCGACACATTGATGATTTGGAGAATATCATTGAA
ATTTTAACACAAAAATTTGACATTATCTTAGACAATTTTCAGAATATAAT
CAAAACTAAAGAAAAAAGTCGAGAATCAACAGAAATTATATTGAATGCCT
TTTCAATGATGGTGGAAAATAGTGAAGATTACCGAAAAGAAAAAATTGAA
GCCATAATTCAAGATGAACTATATAAATTGAATCGGGAAACATATTCATG
TACACCTTTTCAAAGAATTTCACAATATTAAAGAATAATATGATTTAATA
AACATAAATGATTGATTTAACATTGGATAAAGATCATTTCATTTTGTGAA
ATTCATATCGATTTATCATTTATTTATTGAATAATACAATATTGCATTTT
TTGAGAATTATTTATATGATCTGATTATAATCATAAAATTTTTATTTTTC
CCAGTTGGCGAAATTCATGTTTTTCTGTGTTATCTGATATCCCAG
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protein sequence of SMED30033924-orf-1

>SMED30033924-orf-1 ID=SMED30033924-orf-1|Name=SMED30033924-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=786bp
MIFVYFWKITKMLNKSSVIKKNLNIVDSHDNAPCAMDGEYFDNGKITIID
YQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYM
LFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDF
WKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKN
NSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGS
FQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTI
YNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEI
LFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYR
MYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYI
SFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYR
EFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFL
AILDDAYGDIKEELEEKENEFEITDFLKEKSRKVFEKLHLKREKIVDLEN
AMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQ
EQLKMLKELNDQKTALETELIEERDNQEKLIESDAIQPISYGKYMGLSRH
IDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENS
EDYRKEKIEAIIQDELYKLNRETYSCTPFQRISQY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0000464GABAergic neuron
Vocabulary: INTERPRO
TermDefinition
IPR003915PKD_2
IPR002048EF_hand_dom
IPR013122PKD1_2_channel
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
GO:0005262calcium channel activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0050982detection of mechanical stimulus
GO:0070588calcium ion transmembrane transport