Phosphodiesterase

Overview
NamePhosphodiesterase
Smed IDSMED30033910
Length (bp)3678
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Phosphodiesterase (SMED30033910) t-SNE clustered cells

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30033910) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Phosphodiesterase (SMED30033910) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30033910) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033910

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30033910h1SMcG0001498 dd_Smed_v4_7735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30033910h1SMcG0001498 dd_Smed_v4_7735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30033910h1SMcG0001498 dd_Smed_v4_7735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30033910h1SMcG0001498 dd_Smed_v4_7735_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4C (phosphodiesterase 4C [Source:HGNC Symbol;Acc:HGNC:8782])

HSP 1 Score: 536.569 bits (1381), Expect = 5.132e-177
Identity = 288/545 (52.84%), Postives = 375/545 (68.81%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            A SR  S+    H +D+IVTPFAQ+LASLR VR+N   +   Q    A+ G +   S    S +     +D+ + L +ETL+EL+WCL++LE++QT  SV +MAS+KFK+ILN+EL+  ++ S+SGNQ+S+YI  TFLD   +  L + +  E   P  R                          IS  H   H  ++S          V  FG+ + +  ++ + +E T + WG+D+F V+ LS N PLT I F++F++  L + F I +    +++  +E  YH +V YHNS HAADV QST+VLL   +LE VF+DLEI+A +FA  IHDVDHPGV+NQ+LINTN +LALMYNDASVLENHHL+V F +L   NCDI  NL+ KQR S R+MVIDMVLATDMSKHM+LLADLKTMVETKKV   G+L LDNY+DRIQ+LQN+VHCADLSNPTKPL LYR WT++IM EFF+QGD+ERE  L+ISPMCD+ TA+VEKSQV FID+I HPLWETW+DLV+P+AQD+LDTLE NREWY S+I +
Sbjct:   28 AMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPS----SSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSR--------------------------ISGLHGLCHSASLSSA-------TVPRFGVQTDQEEQLAKELEDT-NKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPR 534
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 537.724 bits (1384), Expect = 2.097e-176
Identity = 295/559 (52.77%), Postives = 385/559 (68.87%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S++I  TFLD                        + E++  S T + +       S IS   + +H  +++         ++  FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:   75 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNS-------SIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPE 594
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 537.339 bits (1383), Expect = 2.881e-176
Identity = 295/559 (52.77%), Postives = 385/559 (68.87%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S++I  TFLD                        + E++  S T + +       S IS   + +H  +++         ++  FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:   69 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNS-------SIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPE 588
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 536.954 bits (1382), Expect = 4.817e-176
Identity = 295/559 (52.77%), Postives = 385/559 (68.87%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S++I  TFLD                        + E++  S T + +       S IS   + +H  +++         ++  FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:   83 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNS-------SIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPE 602
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4C (phosphodiesterase 4C [Source:HGNC Symbol;Acc:HGNC:8782])

HSP 1 Score: 536.569 bits (1381), Expect = 5.183e-176
Identity = 288/545 (52.84%), Postives = 375/545 (68.81%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            A SR  S+    H +D+IVTPFAQ+LASLR VR+N   +   Q    A+ G +   S    S +     +D+ + L +ETL+EL+WCL++LE++QT  SV +MAS+KFK+ILN+EL+  ++ S+SGNQ+S+YI  TFLD   +  L + +  E   P  R                          IS  H   H  ++S          V  FG+ + +  ++ + +E T + WG+D+F V+ LS N PLT I F++F++  L + F I +    +++  +E  YH +V YHNS HAADV QST+VLL   +LE VF+DLEI+A +FA  IHDVDHPGV+NQ+LINTN +LALMYNDASVLENHHL+V F +L   NCDI  NL+ KQR S R+MVIDMVLATDMSKHM+LLADLKTMVETKKV   G+L LDNY+DRIQ+LQN+VHCADLSNPTKPL LYR WT++IM EFF+QGD+ERE  L+ISPMCD+ TA+VEKSQV FID+I HPLWETW+DLV+P+AQD+LDTLE NREWY S+I +
Sbjct:  102 AMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPS----SSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSR--------------------------ISGLHGLCHSASLSSA-------TVPRFGVQTDQEEQLAKELEDT-NKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPR 608
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 520.39 bits (1339), Expect = 5.169e-172
Identity = 287/550 (52.18%), Postives = 384/550 (69.82%), Query Frame = 2 
Query: 1472 SLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDN-SLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            S +  RH DDLIVTPFAQ+LASLRNVR+N I ITN+Q+S ++R  + SA    L +    IE  D       +TLEEL+WCL++LE++QTHRSVS+MASSKF+K+LNKELS +A+ SKSG Q+S ++ TT++D + D  S++     E   P   G     + + ++T    + + G   L +  H                  +V  +G+N  R +    +    LD WG D+F +  LS N+ LTV++F+L R+  LF+ F I  S  ++++  +E+ Y ++  YHN  HAADV QS +VLL +  L  VF+DLE++A IFA  +HDVDHPG TNQYLIN+N++LA+MYND SVLE HHL+VAF +L   NCD + NL++KQR  FRK+VIDMVLATDMSKHMSLLADLKTMVE KKVAG+ ++ LD YND+IQ+LQ+M+H ADLSNPTKP+ LY+ W ++IM+E++RQGDKE+E  LEISPMCDR   T+EKSQV FID+IVHPL+ETW+DLVYP+AQ+ILD LE+NREWY S+I +  D   + TE
Sbjct:   20 SGFTLRHGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPLHN----IELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKIS-GVRKLRAPSHDG----------------HVPEYGVNCAREIA---VHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHY-RNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDTARTVTE 544
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 516.924 bits (1330), Expect = 5.994e-170
Identity = 285/544 (52.39%), Postives = 381/544 (70.04%), Query Frame = 2 
Query: 1490 HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDN-SLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            H DDLIVTPFAQ+LASLRNVR+N I ITN+Q+S ++R  + SA    L +    IE  D       +TLEEL+WCL++LE++QTHRSVS+MASSKF+K+LNKELS +A+ SKSG Q+S ++ TT++D + D  S++     E   P   G     + + ++T    + + G   L +  H                  +V  +G+N  R +    +    LD WG D+F +  LS N+ LTV++F+L R+  LF+ F I  S  ++++  +E+ Y ++  YHN  HAADV QS +VLL +  L  VF+DLE++A IFA  +HDVDHPG TNQYLIN+N++LA+MYND SVLE HHL+VAF +L   NCD + NL++KQR  FRK+VIDMVLATDMSKHMSLLADLKTMVE KKVAG+ ++ LD YND+IQ+LQ+M+H ADLSNPTKP+ LY+ W ++IM+E++RQGDKE+E  LEISPMCDR   T+EKSQV FID+IVHPL+ETW+DLVYP+AQ+ILD LE+NREWY S+I +  D   + TE
Sbjct:   76 HGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPLHN----IELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKIS-GVRKLRAPSHDG----------------HVPEYGVNCAREIA---VHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHY-RNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDTARTVTE 594
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 517.309 bits (1331), Expect = 6.070e-170
Identity = 287/560 (51.25%), Postives = 388/560 (69.29%), Query Frame = 2 
Query: 1442 TTTVAASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDN-SLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
             +++A++  G      H DDLIVTPFAQ+LASLRNVR+N I ITN+Q+S ++R  + SA    L +    IE  D       +TLEEL+WCL++LE++QTHRSVS+MASSKF+K+LNKELS +A+ SKSG Q+S ++ TT++D + D  S++     E   P   G     + + ++T    + + G   L +  H                  +V  +G+N  R +    +    LD WG D+F +  LS N+ LTV++F+L R+  LF+ F I  S  ++++  +E+ Y ++  YHN  HAADV QS +VLL +  L  VF+DLE++A IFA  +HDVDHPG TNQYLIN+N++LA+MYND SVLE HHL+VAF +L   NCD + NL++KQR  FRK+VIDMVLATDMSKHMSLLADLKTMVE KKVAG+ ++ LD YND+IQ+LQ+M+H ADLSNPTKP+ LY+ W ++IM+E++RQGDKE+E  LEISPMCDR   T+EKSQV FID+IVHPL+ETW+DLVYP+AQ+ILD LE+NREWY S+I +  D   + TE
Sbjct:   79 ASSIASNEHG------HGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPLHN----IELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKIS-GVRKLRAPSHDG----------------HVPEYGVNCAREIA---VHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHY-RNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDTARTVTE 607
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 517.309 bits (1331), Expect = 9.886e-170
Identity = 287/560 (51.25%), Postives = 388/560 (69.29%), Query Frame = 2 
Query: 1442 TTTVAASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDN-SLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
             +++A++  G      H DDLIVTPFAQ+LASLRNVR+N I ITN+Q+S ++R  + SA    L +    IE  D       +TLEEL+WCL++LE++QTHRSVS+MASSKF+K+LNKELS +A+ SKSG Q+S ++ TT++D + D  S++     E   P   G     + + ++T    + + G   L +  H                  +V  +G+N  R +    +    LD WG D+F +  LS N+ LTV++F+L R+  LF+ F I  S  ++++  +E+ Y ++  YHN  HAADV QS +VLL +  L  VF+DLE++A IFA  +HDVDHPG TNQYLIN+N++LA+MYND SVLE HHL+VAF +L   NCD + NL++KQR  FRK+VIDMVLATDMSKHMSLLADLKTMVE KKVAG+ ++ LD YND+IQ+LQ+M+H ADLSNPTKP+ LY+ W ++IM+E++RQGDKE+E  LEISPMCDR   T+EKSQV FID+IVHPL+ETW+DLVYP+AQ+ILD LE+NREWY S+I +  D   + TE
Sbjct:   91 ASSIASNEHG------HGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPLHN----IELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKIS-GVRKLRAPSHDG----------------HVPEYGVNCAREIA---VHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHY-RNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDTARTVTE 619
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 516.924 bits (1330), Expect = 1.278e-169
Identity = 285/544 (52.39%), Postives = 381/544 (70.04%), Query Frame = 2 
Query: 1490 HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDN-SLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            H DDLIVTPFAQ+LASLRNVR+N I ITN+Q+S ++R  + SA    L +    IE  D       +TLEEL+WCL++LE++QTHRSVS+MASSKF+K+LNKELS +A+ SKSG Q+S ++ TT++D + D  S++     E   P   G     + + ++T    + + G   L +  H                  +V  +G+N  R +    +    LD WG D+F +  LS N+ LTV++F+L R+  LF+ F I  S  ++++  +E+ Y ++  YHN  HAADV QS +VLL +  L  VF+DLE++A IFA  +HDVDHPG TNQYLIN+N++LA+MYND SVLE HHL+VAF +L   NCD + NL++KQR  FRK+VIDMVLATDMSKHMSLLADLKTMVE KKVAG+ ++ LD YND+IQ+LQ+M+H ADLSNPTKP+ LY+ W ++IM+E++RQGDKE+E  LEISPMCDR   T+EKSQV FID+IVHPL+ETW+DLVYP+AQ+ILD LE+NREWY S+I +  D   + TE
Sbjct:  103 HGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPLHN----IELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKIS-GVRKLRAPSHDG----------------HVPEYGVNCAREIA---VHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHY-RNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDTARTVTE 621
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070518)

HSP 1 Score: 540.806 bits (1392), Expect = 1.856e-178
Identity = 295/536 (55.04%), Postives = 387/536 (72.20%), Query Frame = 2 
Query: 1490 HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLK----IEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            H +DLIVTPFAQILASLR+VR N + +TNV +S ++R  + S+S+   RS +       +G+++   L  +T+EEL+WCL++LE++QTHRSVSDMAS KFK++LNKELS +++ S+SGNQIS+YIC+TFLD   +   D  S   + +P    ++     + +      R   G P S IS   + +   T SF       E + TFG+ + R  E+  ++   LDTWG+ IF +   S N PLT +++ +F+  +L     I    FL+F++ +E+ Y KD P+HNS HAADVTQSTNVLL   +LE VF+ LE+   +FA  IHDVDHPG+TNQ+L+N++ +LALMYND SVLENHHL+VAF +L    CDI  N+ KKQRQ+ RKMVID+VL+TDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+L+N+VHCADLSNPTKPL LY+ W   +M+EFF QGDKERE  ++ISPMCDR  AT+EKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE+NR++Y S I
Sbjct:   30 HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSAS--RSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQE--FDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPL-SHTNSFTG-----ERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 554
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333312)

HSP 1 Score: 540.806 bits (1392), Expect = 1.856e-178
Identity = 295/536 (55.04%), Postives = 387/536 (72.20%), Query Frame = 2 
Query: 1490 HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLK----IEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            H +DLIVTPFAQILASLR+VR N + +TNV +S ++R  + S+S+   RS +       +G+++   L  +T+EEL+WCL++LE++QTHRSVSDMAS KFK++LNKELS +++ S+SGNQIS+YIC+TFLD   +   D  S   + +P    ++     + +      R   G P S IS   + +   T SF       E + TFG+ + R  E+  ++   LDTWG+ IF +   S N PLT +++ +F+  +L     I    FL+F++ +E+ Y KD P+HNS HAADVTQSTNVLL   +LE VF+ LE+   +FA  IHDVDHPG+TNQ+L+N++ +LALMYND SVLENHHL+VAF +L    CDI  N+ KKQRQ+ RKMVID+VL+TDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+L+N+VHCADLSNPTKPL LY+ W   +M+EFF QGDKERE  ++ISPMCDR  AT+EKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE+NR++Y S I
Sbjct:   30 HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSAS--RSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQE--FDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPL-SHTNSFTG-----ERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 554
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070521)

HSP 1 Score: 540.806 bits (1392), Expect = 3.416e-178
Identity = 295/536 (55.04%), Postives = 387/536 (72.20%), Query Frame = 2 
Query: 1490 HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLK----IEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            H +DLIVTPFAQILASLR+VR N + +TNV +S ++R  + S+S+   RS +       +G+++   L  +T+EEL+WCL++LE++QTHRSVSDMAS KFK++LNKELS +++ S+SGNQIS+YIC+TFLD   +   D  S   + +P    ++     + +      R   G P S IS   + +   T SF       E + TFG+ + R  E+  ++   LDTWG+ IF +   S N PLT +++ +F+  +L     I    FL+F++ +E+ Y KD P+HNS HAADVTQSTNVLL   +LE VF+ LE+   +FA  IHDVDHPG+TNQ+L+N++ +LALMYND SVLENHHL+VAF +L    CDI  N+ KKQRQ+ RKMVID+VL+TDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+L+N+VHCADLSNPTKPL LY+ W   +M+EFF QGDKERE  ++ISPMCDR  AT+EKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE+NR++Y S I
Sbjct:   50 HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSAS--RSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQE--FDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPL-SHTNSFTG-----ERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 574
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070517)

HSP 1 Score: 541.576 bits (1394), Expect = 7.122e-178
Identity = 295/536 (55.04%), Postives = 387/536 (72.20%), Query Frame = 2 
Query: 1490 HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLK----IEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            H +DLIVTPFAQILASLR+VR N + +TNV +S ++R  + S+S+   RS +       +G+++   L  +T+EEL+WCL++LE++QTHRSVSDMAS KFK++LNKELS +++ S+SGNQIS+YIC+TFLD   +   D  S   + +P    ++     + +      R   G P S IS   + +   T SF       E + TFG+ + R  E+  ++   LDTWG+ IF +   S N PLT +++ +F+  +L     I    FL+F++ +E+ Y KD P+HNS HAADVTQSTNVLL   +LE VF+ LE+   +FA  IHDVDHPG+TNQ+L+N++ +LALMYND SVLENHHL+VAF +L    CDI  N+ KKQRQ+ RKMVID+VL+TDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+L+N+VHCADLSNPTKPL LY+ W   +M+EFF QGDKERE  ++ISPMCDR  AT+EKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE+NR++Y S I
Sbjct:   89 HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSAS--RSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQE--FDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPL-SHTNSFTG-----ERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 613
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333314)

HSP 1 Score: 541.576 bits (1394), Expect = 8.092e-178
Identity = 295/536 (55.04%), Postives = 387/536 (72.20%), Query Frame = 2 
Query: 1490 HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLK----IEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            H +DLIVTPFAQILASLR+VR N + +TNV +S ++R  + S+S+   RS +       +G+++   L  +T+EEL+WCL++LE++QTHRSVSDMAS KFK++LNKELS +++ S+SGNQIS+YIC+TFLD   +   D  S   + +P    ++     + +      R   G P S IS   + +   T SF       E + TFG+ + R  E+  ++   LDTWG+ IF +   S N PLT +++ +F+  +L     I    FL+F++ +E+ Y KD P+HNS HAADVTQSTNVLL   +LE VF+ LE+   +FA  IHDVDHPG+TNQ+L+N++ +LALMYND SVLENHHL+VAF +L    CDI  N+ KKQRQ+ RKMVID+VL+TDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+L+N+VHCADLSNPTKPL LY+ W   +M+EFF QGDKERE  ++ISPMCDR  AT+EKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE+NR++Y S I
Sbjct:   91 HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSAS--RSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQE--FDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPL-SHTNSFTG-----ERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 615
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4d (phosphodiesterase 4D, cAMP-specific [Source:ZFIN;Acc:ZDB-GENE-081105-16])

HSP 1 Score: 545.814 bits (1405), Expect = 7.849e-180
Identity = 296/552 (53.62%), Postives = 387/552 (70.11%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGS-------ISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            + SR  S+    H DD+IVTPFAQ+LASLR VR NF  +TNVQ  R     S       I+ +S+T          +++ + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI +TFLD   +  +      +D +  +R  S+                      IS   +  H  +++         N+  FG+ +    E+ + +E  ++ WG+++F VS  S N PLTV+ + +F++  L + F I    F++++  +E+ YH DV YHN+ HAADVTQST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFF QGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +
Sbjct:   54 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQERSNNKRSPMCNPPPITKTSYT----------EEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQNEVEMPSPQSQKDKEKKKRPMSQ----------------------ISGVKKLTHSSSLTNS-------NIPRFGVKTETEDELAKELED-VNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 565
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4d (phosphodiesterase 4D, cAMP-specific [Source:ZFIN;Acc:ZDB-GENE-081105-16])

HSP 1 Score: 546.199 bits (1406), Expect = 1.903e-179
Identity = 296/552 (53.62%), Postives = 387/552 (70.11%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGS-------ISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            + SR  S+    H DD+IVTPFAQ+LASLR VR NF  +TNVQ  R     S       I+ +S+T          +++ + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI +TFLD   +  +      +D +  +R  S+                      IS   +  H  +++         N+  FG+ +    E+ + +E  ++ WG+++F VS  S N PLTV+ + +F++  L + F I    F++++  +E+ YH DV YHN+ HAADVTQST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFF QGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +
Sbjct:   73 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQERSNNKRSPMCNPPPITKTSYT----------EEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQNEVEMPSPQSQKDKEKKKRPMSQ----------------------ISGVKKLTHSSSLTNS-------NIPRFGVKTETEDELAKELED-VNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 584
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: BX510928.2 (phosphodiesterase 4D, cAMP-specific [Source:NCBI gene;Acc:566998])

HSP 1 Score: 545.043 bits (1403), Expect = 3.379e-179
Identity = 294/547 (53.75%), Postives = 385/547 (70.38%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDL--KIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            + SR  S+    H DD+IVTPFAQ+LASLR VR NF  +TNVQ  R              +S+ L   +  +++ + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI +TFLD   +  +      +D +  +R  S+                      IS   +  H  +++         N+  FG+ +    E+ + +E  ++ WG+++F VS  S N PLTV+ + +F++  L + F I    F++++  +E+ YH DV YHN+ HAADVTQST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFF QGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +
Sbjct:   73 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQERSNN-----------KSDRLPPSLPPEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQNEVEMPSPQSQKDKEKKKRPMSQ----------------------ISGVKKLTHSSSLTNS-------NIPRFGVKTETEDELAKELED-VNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 578
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ca (phosphodiesterase 4C, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-070912-373])

HSP 1 Score: 528.094 bits (1359), Expect = 2.660e-172
Identity = 292/543 (53.78%), Postives = 375/543 (69.06%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            A SR  S     H +D+IVTPFAQ+LASLR VR+NF ++T+ Q     R  S  ++ +   S       ++  + L +ETL+EL+WCLE+LE+++T  SVS+MAS+KFK++LN+EL+Q ++ SKSGNQ+S+YI +TFL+   D  +  T   E     R  S                        IS   +  H   I+         ++  FG+++ R   + + +E   D WG+D+F +S  S N PLTV  +  F++  L + F I    F++++T +E  Y  DV YHNS HAADV QST+VLL   +LE VF+DLEI+A +FA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVIDMVLATDMSKHM+LLADLKTMVETKKV   G+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM EFF QGD+ER+K +EISPMCD+  A++EKSQV FID+IVHPLWETW+DLV+P+AQ+ILDTLE NREWY S I
Sbjct:   98 AMSRNSSTASELHGEDMIVTPFAQVLASLRTVRSNFAVLTHQQD----RVPSKKSTGNNPPSMCKTSLPEEPFQKLAVETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSETSKSGNQVSEYISSTFLEKQHDMDIMSTPSKEKEKKKRPMSQ-----------------------ISGVKKPTHSSNIA-------PSSIPRFGVSTNREDLLAKELED-FDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMI 605
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ca (phosphodiesterase 4C, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-070912-373])

HSP 1 Score: 526.939 bits (1356), Expect = 2.893e-172
Identity = 292/543 (53.78%), Postives = 375/543 (69.06%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            A SR  S     H +D+IVTPFAQ+LASLR VR+NF ++T+ Q         + ++ H   +  L    +  Q+ L +ETL+EL+WCLE+LE+++T  SVS+MAS+KFK++LN+EL+Q ++ SKSGNQ+S+YI +TFL+   D  +  T   E     R  S                        IS   +  H   I+         ++  FG+++ R   + + +E   D WG+D+F +S  S N PLTV  +  F++  L + F I    F++++T +E  Y  DV YHNS HAADV QST+VLL   +LE VF+DLEI+A +FA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVIDMVLATDMSKHM+LLADLKTMVETKKV   G+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM EFF QGD+ER+K +EISPMCD+  A++EKSQV FID+IVHPLWETW+DLV+P+AQ+ILDTLE NREWY S I
Sbjct:   96 AMSRNSSTASELHGEDMIVTPFAQVLASLRTVRSNFAVLTHQQDR-------VPSNGHEYINVLLYFAEEPFQK-LAVETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSETSKSGNQVSEYISSTFLEKQHDMDIMSTPSKEKEKKKRPMSQ-----------------------ISGVKKPTHSSNIA-------PSSIPRFGVSTNREDLLAKELED-FDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMI 599
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 542.732 bits (1397), Expect = 5.063e-178
Identity = 298/544 (54.78%), Postives = 387/544 (71.14%), Query Frame = 2 
Query: 1487 RHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            RH DDLIVTPFAQ+LASLR VR NF  +TN+Q    A   + S S  T+   ++K   +  Q+ L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD        +  E E   P ++           E ++ +R      S IS   + +H  +++         N+  FG+ S     + + +E  ++ WG++IF V+  S N PLTV+   +F++ ++ + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQ  RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P E E
Sbjct:  111 RHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD--RAPNCATSDSPPTMCKRNIKNIKEAYQK-LAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD--------KQHEVEMPSPAQK-----------EKEKKKRPM----SQISGVKKLMHSSSLTNS-------NIPRFGVKSENEECLAKELED-VNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQE 620
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 541.191 bits (1393), Expect = 7.078e-178
Identity = 295/560 (52.68%), Postives = 385/560 (68.75%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDL-KIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E   K+ G+  +          L+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD        +  E E   P ++           E ++ +R      S IS   + +H  +++         N+  FG+ S     + + +E  ++ WG++IF V+  S N PLTV+   +F++ ++ + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQ  RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P E E
Sbjct:   75 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKLAGETLEE---------LDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD--------KQHEVEMPSPAQK-----------EKEKKKRPM----SQISGVKKLMHSSSLTNS-------NIPRFGVKSENEECLAKELED-VNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQE 594
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 541.191 bits (1393), Expect = 8.504e-178
Identity = 295/560 (52.68%), Postives = 385/560 (68.75%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDL-KIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E   K+ G+  +          L+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD        +  E E   P ++           E ++ +R      S IS   + +H  +++         N+  FG+ S     + + +E  ++ WG++IF V+  S N PLTV+   +F++ ++ + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQ  RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P E E
Sbjct:   83 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKLAGETLEE---------LDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD--------KQHEVEMPSPAQK-----------EKEKKKRPM----SQISGVKKLMHSSSLTNS-------NIPRFGVKSENEECLAKELED-VNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQE 602
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 541.191 bits (1393), Expect = 1.041e-177
Identity = 295/560 (52.68%), Postives = 385/560 (68.75%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDL-KIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E   K+ G+  +          L+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD        +  E E   P ++           E ++ +R      S IS   + +H  +++         N+  FG+ S     + + +E  ++ WG++IF V+  S N PLTV+   +F++ ++ + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQ  RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P E E
Sbjct:   82 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKLAGETLEE---------LDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD--------KQHEVEMPSPAQK-----------EKEKKKRPM----SQISGVKKLMHSSSLTNS-------NIPRFGVKSENEECLAKELED-VNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQE 601
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 538.88 bits (1387), Expect = 1.080e-177
Identity = 292/555 (52.61%), Postives = 380/555 (68.47%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q      +     +   L  E L+                EL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD        +  E E   P ++           E ++ +R      S IS   + +H  +++         N+  FG+ S     + + +E  ++ WG++IF V+  S N PLTV+   +F++ ++ + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQ  RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P E E
Sbjct:   37 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRYPFPYLLTEEAYQKLAGETLE----------------ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD--------KQHEVEMPSPAQK-----------EKEKKKR----PMSQISGVKKLMHSSSLTNS-------NIPRFGVKSENEECLAKELED-VNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQE 544
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 538.88 bits (1387), Expect = 5.127e-177
Identity = 297/559 (53.13%), Postives = 384/559 (68.69%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD                        + E++  S T + +       S IS   + +H  +++   I         FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:   75 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI-------PRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQE 594
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 538.11 bits (1385), Expect = 2.029e-176
Identity = 297/559 (53.13%), Postives = 384/559 (68.69%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD                        + E++  S T + +       S IS   + +H  +++   I         FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:   97 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI-------PRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQE 616
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 537.724 bits (1384), Expect = 2.483e-176
Identity = 297/559 (53.13%), Postives = 384/559 (68.69%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD                        + E++  S T + +       S IS   + +H  +++   I         FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:   95 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI-------PRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQE 614
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 539.65 bits (1389), Expect = 3.306e-176
Identity = 297/559 (53.13%), Postives = 384/559 (68.69%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD                        + E++  S T + +       S IS   + +H  +++   I         FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:  151 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI-------PRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQE 670
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 538.88 bits (1387), Expect = 4.110e-176
Identity = 297/559 (53.13%), Postives = 384/559 (68.69%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD                        + E++  S T + +       S IS   + +H  +++   I         FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:  144 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI-------PRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQE 663
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q8IRU4|PDE4E_DROME (cAMP-specific 3',5'-cyclic phosphodiesterase, isoform F OS=Drosophila melanogaster OX=7227 GN=dnc PE=3 SV=1)

HSP 1 Score: 540.806 bits (1392), Expect = 3.424e-177
Identity = 295/536 (55.04%), Postives = 387/536 (72.20%), Query Frame = 2 
Query: 1490 HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLK----IEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            H +DLIVTPFAQILASLR+VR N + +TNV +S ++R  + S+S+   RS +       +G+++   L  +T+EEL+WCL++LE++QTHRSVSDMAS KFK++LNKELS +++ S+SGNQIS+YIC+TFLD   +   D  S   + +P    ++     + +      R   G P S IS   + +   T SF       E + TFG+ + R  E+  ++   LDTWG+ IF +   S N PLT +++ +F+  +L     I    FL+F++ +E+ Y KD P+HNS HAADVTQSTNVLL   +LE VF+ LE+   +FA  IHDVDHPG+TNQ+L+N++ +LALMYND SVLENHHL+VAF +L    CDI  N+ KKQRQ+ RKMVID+VL+TDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+L+N+VHCADLSNPTKPL LY+ W   +M+EFF QGDKERE  ++ISPMCDR  AT+EKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE+NR++Y S I
Sbjct:   50 HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSAS--RSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQE--FDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPL-SHTNSFTG-----ERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 574
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q01063|PDE4D_MOUSE (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Mus musculus OX=10090 GN=Pde4d PE=1 SV=2)

HSP 1 Score: 538.88 bits (1387), Expect = 2.875e-175
Identity = 297/559 (53.13%), Postives = 384/559 (68.69%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            + SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S+YI  TFLD                        + E++  S T + +       S IS   + +H  +++   I         FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:  144 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI-------PRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQE 663
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q08493|PDE4C_HUMAN (cAMP-specific 3',5'-cyclic phosphodiesterase 4C OS=Homo sapiens OX=9606 GN=PDE4C PE=1 SV=2)

HSP 1 Score: 536.954 bits (1382), Expect = 5.526e-175
Identity = 288/545 (52.84%), Postives = 375/545 (68.81%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            A SR  S+    H +D+IVTPFAQ+LASLR VR+N   +   Q    A+ G +   S    S +     +D+ + L +ETL+EL+WCL++LE++QT  SV +MAS+KFK+ILN+EL+  ++ S+SGNQ+S+YI  TFLD   +  L + +  E   P  R                          IS  H   H  ++S          V  FG+ + +  ++ + +E T + WG+D+F V+ LS N PLT I F++F++  L + F I +    +++  +E  YH +V YHNS HAADV QST+VLL   +LE VF+DLEI+A +FA  IHDVDHPGV+NQ+LINTN +LALMYNDASVLENHHL+V F +L   NCDI  NL+ KQR S R+MVIDMVLATDMSKHM+LLADLKTMVETKKV   G+L LDNY+DRIQ+LQN+VHCADLSNPTKPL LYR WT++IM EFF+QGD+ERE  L+ISPMCD+ TA+VEKSQV FID+I HPLWETW+DLV+P+AQD+LDTLE NREWY S+I +
Sbjct:  134 AMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPS----SSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSR--------------------------ISGLHGLCHSASLSSA-------TVPRFGVQTDQEEQLAKELEDT-NKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPR 640
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q9W4S9|PDE4C_DROME (cAMP-specific 3',5'-cyclic phosphodiesterase, isoforms N/G OS=Drosophila melanogaster OX=7227 GN=dnc PE=3 SV=2)

HSP 1 Score: 543.502 bits (1399), Expect = 6.385e-174
Identity = 298/546 (54.58%), Postives = 391/546 (71.61%), Query Frame = 2 
Query: 1460 SRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLK----IEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            SR  S+    H +DLIVTPFAQILASLR+VR N + +TNV +S ++R  + S+S+   RS +       +G+++   L  +T+EEL+WCL++LE++QTHRSVSDMAS KFK++LNKELS +++ S+SGNQIS+YIC+TFLD   +   D  S   + +P    ++     + +      R   G P S IS   + +   T SF       E + TFG+ + R  E+  ++   LDTWG+ IF +   S N PLT +++ +F+  +L     I    FL+F++ +E+ Y KD P+HNS HAADVTQSTNVLL   +LE VF+ LE+   +FA  IHDVDHPG+TNQ+L+N++ +LALMYND SVLENHHL+VAF +L    CDI  N+ KKQRQ+ RKMVID+VL+TDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+L+N+VHCADLSNPTKPL LY+ W   +M+EFF QGDKERE  ++ISPMCDR  AT+EKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE+NR++Y S I
Sbjct:  361 SRNSSIASESHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSAS--RSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQE--FDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPL-SHTNSFTG-----ERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMI 895
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q08499|PDE4D_HUMAN (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens OX=9606 GN=PDE4D PE=1 SV=2)

HSP 1 Score: 537.724 bits (1384), Expect = 6.749e-174
Identity = 295/557 (52.96%), Postives = 384/557 (68.94%), Query Frame = 2 
Query: 1460 SRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQ----SSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            SR  S+    H DDLIVTPFAQ+LASLR VR NF  +TN+Q    S R       S +  T+  E        + + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S++I  TFLD                        + E++  S T + +       S IS   + +H  +++         ++  FG+ + +   + + +E  ++ WG+ +F ++ LS N PLTVI   +F++  L + F I     ++++  +E+ YH DV YHN+ HAADV QST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFFRQGD+ERE+ +EISPMCD+  A+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I +     P + E
Sbjct:  207 SRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE--------AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLD-----------------------KQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNS-------SIPRFGVKTEQEDVLAKELED-VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPE 724
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3KF73 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106181325 PE=3 SV=1)

HSP 1 Score: 584.334 bits (1505), Expect = 0.000e+0
Identity = 316/553 (57.14%), Postives = 404/553 (73.06%), Query Frame = 2 
Query: 1433 SVPTTTVAASRRG-SLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIE--GDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            S+P T  A+     S + FRH+DDLIVTPFAQILASLR+VR N+IL+TN  +S+  R GS  + +   + ++L      +++   L++ETLEEL+WCL++LE++QTHRSVSDMASSKFK++LN+ELS +A+ SKSGNQIS+YIC+TFLD   +  L          P  +G    E +++     +    D    +      +  K   SF        +V  FG+       + +++   +D WG+DIF ++  S N PLT + + +FR+ +L + F I     L+++  +E+ Y +DVPYHN+ HAADVTQST+VLL A +LENVF+DLEI+A IFAC IHDVDHPGVTNQ+LINT+ +LALMYND SVLENHHL+VAF +L+  NCDI  NL KKQRQ+ R+MVIDMVLATDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+LQNMVHC+DLSNPTKPL+LY+ WT +IM EFFRQGD EREK+L+ISPMCD+  ATVEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NR+WY S I
Sbjct:   31 SLPRTVRASCLSSYSRFSFRHADDLIVTPFAQILASLRSVRNNYILLTNAPTSKTRR-GSAHSGNTMNQHQNLNTPKLSEEAFTKLSVETLEELDWCLDQLETIQTHRSVSDMASSKFKRMLNRELSHFAESSKSGNQISEYICSTFLDKQQEMDL----------PVMKGDDHHEHNQNQSNKYNREIKDKKTPMSQIMGVRKLKHANSFTG-----GSVPRFGVECANEDGLGKLL-NDIDKWGVDIFKIAEYSKNRPLTCVVYTVFRERELLKNFQIPPQTLLTYLMHLEDHYRRDVPYHNNVHAADVTQSTHVLLSAPALENVFTDLEILAAIFACAIHDVDHPGVTNQFLINTSSELALMYNDESVLENHHLAVAFKLLTEENCDIFANLNKKQRQTLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLQNMVHCSDLSNPTKPLDLYKQWTTRIMDEFFRQGDIEREKDLDISPMCDKHNATVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYQSMI 566
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A4S2M0L3 (Phosphodiesterase (Fragment) OS=Opisthorchis felineus OX=147828 GN=CRM22_004620 PE=3 SV=1)

HSP 1 Score: 583.178 bits (1502), Expect = 0.000e+0
Identity = 329/611 (53.85%), Postives = 427/611 (69.89%), Query Frame = 2 
Query: 1412 SNVVVDHSVPTTTVAASRRG------SLYIFRHS------------DDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSED---LKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLD---ADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSL---------ISNEHQKIHKQTISFKPIFVDIENVSTF--------GINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK---IEDKDPSE 3112
            SN+V+ H +P    +   RG      SLY  RH             D+ IVTPFAQILASLR +RANFI +TN+ SS+++RFG+    SHT   +D   + +  ++  +    ETLEELEWCLERLE++QTHRSVSDMA+SKF+K+LNKELSQ+ D  ++  QIS+YIC+TFLD    D + ++    E    +   R S++        ++ +E    GAPSL           +EHQ + K      P+  D    +++        G+ S +   + + I T LD WG+DIF +S L+ +NPLT + +A+F+K  L ++FSI     + +   IE KY+ DVPYHN  HAADV QST+VLL A +L +VF+DLE+MAV+FAC IHDVDHPG+TNQ+LINTN++LA++YND SVLENHHL+V F +L+ P CDI+ N+ KKQR S R+MVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGIL LDNY+DR+QILQNM+HCADLSNPTK LNLYR W  +IM+E FRQGD+ERE+ L++SPMCDR TA++EK+QVSFID+IVHPLWETWSDLV+P+A  ILDTL++NREWY +QI+K    ED +P E
Sbjct:   22 SNLVL-HHIPDRRCSFLYRGESDDNYSLYSSRHPSITGEEAHVDHVDEPIVTPFAQILASLRRIRANFIFLTNITSSKDSRFGT----SHTNFGDDGQNMALIQEEQLKVSASETLEELEWCLERLENIQTHRSVSDMATSKFRKMLNKELSQFTDGCENAKQISEYICSTFLDPNEVDPNTAITHLPEMASNENLSRDSAKATNVTQKTSNSTEMRVSGAPSLNIADTEGPKADDEHQGLPKAKKESFPL-CDRSTPTSYLSADALPPGLKSDQMARLKQFIVTGLDQWGVDIFELSQLT-SNPLTCLFYAIFQKRGLIKRFSIPEMNLVRYANLIEEKYN-DVPYHNRVHAADVLQSTHVLLNASALMSVFTDLEVMAVLFACAIHDVDHPGLTNQFLINTNNELAILYNDTSVLENHHLAVGFQLLTRPGCDILENVPKKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILTLDNYSDRMQILQNMIHCADLSNPTKSLNLYRQWNARIMEEHFRQGDRERERGLDLSPMCDRTTASIEKTQVSFIDYIVHPLWETWSDLVHPDALQILDTLDENREWYLNQIAKETVSEDSEPPE 624
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A2C9KA62 (Phosphodiesterase OS=Biomphalaria glabrata OX=6526 GN=106059246 PE=3 SV=1)

HSP 1 Score: 582.408 bits (1500), Expect = 0.000e+0
Identity = 308/549 (56.10%), Postives = 395/549 (71.95%), Query Frame = 2 
Query: 1481 IFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSE-----------DLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELD------EHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFS 3076
            + +H++DLIVTPFAQILASLR+VRAN+I +TNV +    R GS    +H L ++                G D    L  ETLEEL+WC+E+LE++QTHRSVSDMASSKFK++LN+ELS +A+ SKSGNQI++YIC+T+LD                        ++ELD      +H +T    +  D    +      +  K   SF  I      V T G+ +    E+T+I+   +D WG+DIF V+  S+N PLT +++ +F++ +L + F+I     ++++  +E+ YH+D PYHN+ HAADVTQST+VLL A +LENVF+DLEI+A IFAC IHDVDHPG+TNQYLI T+ +LALMYND SVLENHHL+VAF +L   NCDI+  LTKKQRQSFRKMVIDMVLATDMSKHM+LLADLKTMVETKKVAGSG+L LDNY DRIQ+LQNMVHCADLSNPTKPL +Y++W +++M EFF+QGD+ER   L+ISPMCDR TAT+EKSQV FID+IVHPLWETW+DLVYP+AQ+ILDTLE NR+WY +
Sbjct:  492 VTQHAEDLIVTPFAQILASLRSVRANYINLTNVPNKERTRRGSSDRHAHGLLNQASMSPQHHQLSPGASRGSDGYMKLATETLEELDWCMEQLETIQTHRSVSDMASSKFKRMLNRELSHFAESSKSGNQIAEYICSTYLD-----------------------KQQELDLPTLKVDHVDTVVKAKNIDKTRPMCQISGLRKLKHANSFTGI------VPTHGVETPYKEELTKIL-NDIDKWGIDIFKVNEFSNNRPLTCVTYTIFQERELLKTFNIAPHTLVTYMMHVEDHYHRDTPYHNAIHAADVTQSTHVLLSATALENVFTDLEILAAIFACTIHDVDHPGLTNQYLIQTSSELALMYNDESVLENHHLAVAFKLLQEENCDILDKLTKKQRQSFRKMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGVLLLDNYQDRIQVLQNMVHCADLSNPTKPLEIYKTWVDRVMAEFFKQGDQERLLGLDISPMCDRHTATIEKSQVGFIDYIVHPLWETWADLVYPDAQEILDTLEDNRDWYHA 1010
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3KF58 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106181325 PE=3 SV=1)

HSP 1 Score: 581.252 bits (1497), Expect = 0.000e+0
Identity = 313/543 (57.64%), Postives = 398/543 (73.30%), Query Frame = 2 
Query: 1460 SRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIE--GDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            SR  SL    H+DDLIVTPFAQILASLR+VR N+IL+TN  +S+  R GS  + +   + ++L      +++   L++ETLEEL+WCL++LE++QTHRSVSDMASSKFK++LN+ELS +A+ SKSGNQIS+YIC+TFLD   +  L          P  +G    E +++     +    D    +      +  K   SF        +V  FG+       + +++   +D WG+DIF ++  S N PLT + + +FR+ +L + F I     L+++  +E+ Y +DVPYHN+ HAADVTQST+VLL A +LENVF+DLEI+A IFAC IHDVDHPGVTNQ+LINT+ +LALMYND SVLENHHL+VAF +L+  NCDI  NL KKQRQ+ R+MVIDMVLATDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+LQNMVHC+DLSNPTKPL+LY+ WT +IM EFFRQGD EREK+L+ISPMCD+  ATVEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NR+WY S I
Sbjct:  196 SRNSSLTSELHADDLIVTPFAQILASLRSVRNNYILLTNAPTSK-TRRGSAHSGNTMNQHQNLNTPKLSEEAFTKLSVETLEELDWCLDQLETIQTHRSVSDMASSKFKRMLNRELSHFAESSKSGNQISEYICSTFLDKQQEMDL----------PVMKGDDHHEHNQNQSNKYNREIKDKKTPMSQIMGVRKLKHANSFTG-----GSVPRFGVECANEDGLGKLL-NDIDKWGVDIFKIAEYSKNRPLTCVVYTVFRERELLKNFQIPPQTLLTYLMHLEDHYRRDVPYHNNVHAADVTQSTHVLLSAPALENVFTDLEILAAIFACAIHDVDHPGVTNQFLINTSSELALMYNDESVLENHHLAVAFKLLTEENCDIFANLNKKQRQTLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLQNMVHCSDLSNPTKPLDLYKQWTTRIMDEFFRQGDIEREKDLDISPMCDKHNATVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYQSMI 721
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3KFW4 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106181325 PE=3 SV=1)

HSP 1 Score: 580.867 bits (1496), Expect = 0.000e+0
Identity = 313/543 (57.64%), Postives = 398/543 (73.30%), Query Frame = 2 
Query: 1460 SRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIE--GDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            SR  SL    H+DDLIVTPFAQILASLR+VR N+IL+TN  +S+  R GS  + +   + ++L      +++   L++ETLEEL+WCL++LE++QTHRSVSDMASSKFK++LN+ELS +A+ SKSGNQIS+YIC+TFLD   +  L          P  +G    E +++     +    D    +      +  K   SF        +V  FG+       + +++   +D WG+DIF ++  S N PLT + + +FR+ +L + F I     L+++  +E+ Y +DVPYHN+ HAADVTQST+VLL A +LENVF+DLEI+A IFAC IHDVDHPGVTNQ+LINT+ +LALMYND SVLENHHL+VAF +L+  NCDI  NL KKQRQ+ R+MVIDMVLATDMSKHMSLLADLKTMVETKKVAGSG+L LDNY DRIQ+LQNMVHC+DLSNPTKPL+LY+ WT +IM EFFRQGD EREK+L+ISPMCD+  ATVEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NR+WY S I
Sbjct:  197 SRNSSLTSELHADDLIVTPFAQILASLRSVRNNYILLTNAPTSK-TRRGSAHSGNTMNQHQNLNTPKLSEEAFTKLSVETLEELDWCLDQLETIQTHRSVSDMASSKFKRMLNRELSHFAESSKSGNQISEYICSTFLDKQQEMDL----------PVMKGDDHHEHNQNQSNKYNREIKDKKTPMSQIMGVRKLKHANSFTG-----GSVPRFGVECANEDGLGKLL-NDIDKWGVDIFKIAEYSKNRPLTCVVYTVFRERELLKNFQIPPQTLLTYLMHLEDHYRRDVPYHNNVHAADVTQSTHVLLSAPALENVFTDLEILAAIFACAIHDVDHPGVTNQFLINTSSELALMYNDESVLENHHLAVAFKLLTEENCDIFANLNKKQRQTLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLQNMVHCSDLSNPTKPLDLYKQWTTRIMDEFFRQGDIEREKDLDISPMCDKHNATVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYQSMI 722
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 533.487 bits (1373), Expect = 1.007e-174
Identity = 290/542 (53.51%), Postives = 377/542 (69.56%), Query Frame = 2 
Query: 1487 RHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSE 3112
            RH +D+IVTPFAQ+LASLR VR+NF  +T++Q     R G    +     S       DD+   L +ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+Q ++ S+SGNQ+S++I +TFL+   D       E     P  +   R  + + S   +       AP+ I                          FG+++     + + +E  ++ WG+DIF ++  S N PLTVI +++F++  L + F I +  F++F+  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEIMA +FA  IHDVDHPGV+NQ+LINTN +LALMYNDASVLENHHL+V F +L   NCDI  NL+KKQRQS RKMVIDMVLATDMSKHM+ LADLKTMVETKKV   G+L LDNY+DRIQ+LQNMVHCADLSNPTKPL +YR WT++IM E+F QGD+ER++ +EISPMCD+ TA+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I       P E
Sbjct:  104 RHGEDMIVTPFAQVLASLRTVRSNFAALTHLQD----RGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHD------VEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPR------------------------FGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSPSPTPEE 610
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 533.872 bits (1374), Expect = 1.140e-174
Identity = 290/542 (53.51%), Postives = 377/542 (69.56%), Query Frame = 2 
Query: 1487 RHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSE 3112
            RH +D+IVTPFAQ+LASLR VR+NF  +T++Q     R G    +     S       DD+   L +ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+Q ++ S+SGNQ+S++I +TFL+   D       E     P  +   R  + + S   +       AP+ I                          FG+++     + + +E  ++ WG+DIF ++  S N PLTVI +++F++  L + F I +  F++F+  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEIMA +FA  IHDVDHPGV+NQ+LINTN +LALMYNDASVLENHHL+V F +L   NCDI  NL+KKQRQS RKMVIDMVLATDMSKHM+ LADLKTMVETKKV   G+L LDNY+DRIQ+LQNMVHCADLSNPTKPL +YR WT++IM E+F QGD+ER++ +EISPMCD+ TA+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I       P E
Sbjct:  120 RHGEDMIVTPFAQVLASLRTVRSNFAALTHLQD----RGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHD------VEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPR------------------------FGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSPSPTPEE 626
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 534.643 bits (1376), Expect = 1.575e-174
Identity = 290/542 (53.51%), Postives = 377/542 (69.56%), Query Frame = 2 
Query: 1487 RHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSE 3112
            RH +D+IVTPFAQ+LASLR VR+NF  +T++Q     R G    +     S       DD+   L +ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+Q ++ S+SGNQ+S++I +TFL+   D       E     P  +   R  + + S   +       AP+ I                          FG+++     + + +E  ++ WG+DIF ++  S N PLTVI +++F++  L + F I +  F++F+  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEIMA +FA  IHDVDHPGV+NQ+LINTN +LALMYNDASVLENHHL+V F +L   NCDI  NL+KKQRQS RKMVIDMVLATDMSKHM+ LADLKTMVETKKV   G+L LDNY+DRIQ+LQNMVHCADLSNPTKPL +YR WT++IM E+F QGD+ER++ +EISPMCD+ TA+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I       P E
Sbjct:  149 RHGEDMIVTPFAQVLASLRTVRSNFAALTHLQD----RGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHD------VEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPR------------------------FGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSPSPTPEE 655
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 534.258 bits (1375), Expect = 2.474e-174
Identity = 294/542 (54.24%), Postives = 382/542 (70.48%), Query Frame = 2 
Query: 1487 RHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSE 3112
            RH +D+IVTPFAQ+LASLR VR+NF  +T++Q     R G    +     S       DD+   L +ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+Q ++ S+SGNQ+S++I +TFL+   D         E   PP +           E ++  R      S IS   +  H  + S  P  +       FG+++     + + +E  ++ WG+DIF ++  S N PLTVI +++F++  L + F I +  F++F+  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEIMA +FA  IHDVDHPGV+NQ+LINTN +LALMYNDASVLENHHL+V F +L   NCDI  NL+KKQRQS RKMVIDMVLATDMSKHM+ LADLKTMVETKKV   G+L LDNY+DRIQ+LQNMVHCADLSNPTKPL +YR WT++IM E+F QGD+ER++ +EISPMCD+ TA+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I       P E
Sbjct:  155 RHGEDMIVTPFAQVLASLRTVRSNFAALTHLQD----RGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHD--------VEILSPPPK-----------EKEKKRRPM----SQISGVKKLTH--SPSLAPTCI-----PRFGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSPSPTPEE 661
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 533.487 bits (1373), Expect = 2.652e-174
Identity = 293/553 (52.98%), Postives = 380/553 (68.72%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSE 3112
            A SR  S     H +D+IVTPFAQ+LASLR VR+NF  +T++Q     R G    +     S       DD+   L +ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+Q ++ S+SGNQ+S++I +TFL+   D       E     P  +   R  + + S   +       AP+ I                          FG+++     + + +E  ++ WG+DIF ++  S N PLTVI +++F++  L + F I +  F++F+  +E+ YH DV YHN+ HAADV QST+VLL + +LE VF+DLEIMA +FA  IHDVDHPGV+NQ+LINTN +LALMYNDASVLENHHL+V F +L   NCDI  NL+KKQRQS RKMVIDMVLATDMSKHM+ LADLKTMVETKKV   G+L LDNY+DRIQ+LQNMVHCADLSNPTKPL +YR WT++IM E+F QGD+ER++ +EISPMCD+ TA+VEKSQV FID+IVHPLWETW+DLV+P+AQDILDTLE NREWY S I       P E
Sbjct:  121 AMSRNSSTASELHGEDMIVTPFAQVLASLRTVRSNFAALTHLQD----RGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHD------VEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPR------------------------FGVSTEHESLLAKEVED-INRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSPSPTPEE 638
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007435.1 (pep scaffold:Pmarinus_7.0:GL486982:1709:8825:-1 gene:ENSPMAG00000006710.1 transcript:ENSPMAT00000007435.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 323.553 bits (828), Expect = 4.023e-103
Identity = 150/203 (73.89%), Postives = 176/203 (86.70%), Query Frame = 2 
Query: 2390 SLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQ-VSFIDFIVHPLW 2995
            S + VF+DLEI+A IFA  IHDVDHPGV+NQ+LINTN +LALMYND SVLENHHL+V F +L   NCDI  NL+KKQRQ+ RKMVIDMVLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY DRIQ+LQNMVHCADLSNPTKPL++YR WTE+IM+EFFRQGD+ERE+ +EISPMCD+ +A+VEKSQ ++ IDF +H  W
Sbjct:    3 SPQAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLQNMVHCADLSNPTKPLDVYRQWTERIMEEFFRQGDRERERGMEISPMCDKHSASVEKSQRINAIDFSLHCWW 205
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde4ba (phosphodiesterase 4B, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-030131-9570])

HSP 1 Score: 277.715 bits (709), Expect = 4.901e-84
Identity = 174/391 (44.50%), Postives = 252/391 (64.45%), Query Frame = 2 
Query: 1490 HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTS--EYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMV 2656
            H DDLIVTPFAQ+LASLR+VR NF  +TN+Q +   R  + + +S+   +       D+  + L +ET+EEL+WCL++LE++QTHRSVS+MAS+KFK++LN+ELS  ++ S+SGNQ+S++I +TF+D   +  +      E E    P            +      + A G  S IS   + +H   I        ++    F    ++ +E        ++ WG++IF ++ LS+N PLTV+ + +F++ +L + F I +  F++++  +E+ +H  V YHNS HAADV QST+VLL + +L+ VF+DLEI+A IFA  IHDVDHPGV+NQ+LI+TN +LALMYND SVLENHHL+V F +L   NCDI  NL KKQRQ+ RKMVIDMV
Sbjct:    1 HGDDLIVTPFAQVLASLRSVRNNFSALTNLQGTPSRRSPAGNQTSYPRAAP-----SDEGYQKLALETMEELDWCLDQLEAVQTHRSVSEMASNKFKRMLNRELSHLSEMSRSGNQVSEFISSTFMDKQHEMEVPSAGHKEKERQRRPLASGGGVAAVGGAAPAVPSQLAAGV-SHISGVQRLLHGAAI--------LQRAMIFRDALSQELE-------DINKWGINIFRIAELSNNRPLTVLMYTIFQERELLKTFQIPADTFVTYMMTLED-HHAGVAYHNSLHAADVAQSTHVLLASPALDAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLGKKQRQTLRKMVIDMV 369
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007498.1 (pep scaffold:Pmarinus_7.0:GL486417:1684:4657:1 gene:ENSPMAG00000006774.1 transcript:ENSPMAT00000007498.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 243.432 bits (620), Expect = 8.579e-75
Identity = 109/143 (76.22%), Postives = 129/143 (90.21%), Query Frame = 2 
Query: 2654 VLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQI 3082
            VLATDMSKHM+LL DLKT VETKKV  SG+L LDNY DRIQ+LQNMVHCADLSNPTKPL LYR WTE+IM+EFF+QGD+ERE+ ++ISPMCDR +A+VEKSQV FID+IVHPLWETW+DLV P+AQ++LDTLE+NR++Y S I
Sbjct:    2 VLATDMSKHMNLLGDLKTTVETKKVTSSGVLLLDNYTDRIQVLQNMVHCADLSNPTKPLGLYRQWTERIMEEFFQQGDRERERGIDISPMCDRHSASVEKSQVGFIDYIVHPLWETWADLVQPDAQEMLDTLEENRDFYQSTI 144
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE1C (phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:8776])

HSP 1 Score: 213.001 bits (541), Expect = 2.099e-60
Identity = 118/292 (40.41%), Postives = 175/292 (59.93%), Query Frame = 2 
Query: 2147 LDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKY--HKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSL-PNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDL 3013
            +D W  D+F +   S  + L  I + LF +Y L  +F I  S  +SF+  +E  Y  HK+ PYHNS HAADVTQ+ + L+      +  ++LEI+++IFA  IHD +H G TN + I T    A++YND SVLENHH+S A+ ++      +I+ NL+K   +  R +V++ VLATDMS H   L  +K +++  +    G+       ++ + +  M+H AD+S+P K  NL+R WT  +M+EFFRQGDKE E  L  SP+CDR    V +SQ+ FID+IV P +   +DL
Sbjct:  141 VDKWSFDVFALHEASGEHALKFIVYELFTRYDLIARFKIPVSSVVSFVEALEAGYSKHKN-PYHNSVHAADVTQTVHYLMLKTGTIHWLNELEILSMIFAAAIHDYEHTGTTNNFHIQTRSDSAILYNDRSVLENHHVSAAYRLMQEDEEMNILINLSKDDWRELRALVVETVLATDMSCHFHQLKSIKNLLQQPE----GV-------EKPKAMSLMLHTADISHPAKNWNLHRRWTMSLMEEFFRQGDKEAELGLSFSPLCDRNATMVPQSQIGFIDYIVEPTFTVLTDL 420
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde1a (phosphodiesterase 1A, calmodulin-dependent [Source:ZFIN;Acc:ZDB-GENE-090831-2])

HSP 1 Score: 215.312 bits (547), Expect = 2.411e-60
Identity = 118/319 (36.99%), Postives = 188/319 (58.93%), Query Frame = 2 
Query: 2096 GINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKY--HKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDL----VYPEAQD 3034
            G++   NV +  +   T   W  D+F+++  S  + L  +   L  +Y+L  ++ I  +  +SF+  +E  Y  HK+ PYHN  HAADVTQ+ + LL    L +  S+LE +AVIFA  IHD++H G TN + I T   +AL+YND +VLENHH+S A+ ++   + +I  NL+K   +  R +V++MVLATDMS H   +  +K+ ++  +             D+ + +  ++H  D+S+PTK   L++ WTE +M+EFFRQGD+E +  L  SP+CDR +  V +SQ+ F+DFIV P +   +D+    V P A++
Sbjct:  134 GLSYPPNV-LVALKNWTCHKWSFDVFVLNEASGEHALKFVMHELLTRYELISRYKIPVAALVSFVEALEAGYSKHKN-PYHNLAHAADVTQTVHYLLLQSGLMHWLSELETLAVIFAAAIHDLEHTGTTNNFHIQTRSDVALLYNDRAVLENHHVSAAYRLMQDDDMNIFINLSKDDWRELRALVVEMVLATDMSCHFQQIKTMKSALQQPESI-----------DKSKAMSLLLHAGDISHPTKEWPLHQRWTEALMEEFFRQGDREAKLGLPFSPLCDRNSTMVAQSQIGFMDFIVEPTFSVLTDMAEKVVVPLAEE 439
[Close]
BLAST of Phosphodiesterase vs. Ensembl Yeast
Match: PDE2 (High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon [Source:SGD;Acc:S000005887])

HSP 1 Score: 71.2478 bits (173), Expect = 4.185e-13
Identity = 68/242 (28.10%), Postives = 111/242 (45.87%), Query Frame = 2 
Query: 2147 LDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEF 2872
            L TW      +ST      L    F L +K     K  I  +  L  +  +E+ YH+   +HN  HA DV Q+T  L   L  +N    ++ + +  A I HDV HPG  NQ L N   ++A  + + S+LEN H  +   +LS  +   + +++KK+       + + +LATDM+ H        +  E +       L  +N   +I ++  ++  AD+SN T+ L++   W   I  EF
Sbjct:  208 LSTWDFCALSLST----QELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDN---PVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLS-EHWPQLLSISKKKFD----FISEAILATDMALH--------SQYEDR-------LMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEF 422
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO46133 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM4])

HSP 1 Score: 459.914 bits (1182), Expect = 1.578e-149
Identity = 249/533 (46.72%), Postives = 350/533 (65.67%), Query Frame = 2 
Query: 1505 IVTPFAQILASLRNVRANFILITNVQSSREARFGSISAS--SHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVA--GSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKERE-KNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            +VTPFAQIL+SLRNVR  F+ +TN +  ++ +      S  SH+  S       D+            L+W L +LE++QTH SVS+MAS+KFK++LN+EL  +++ ++SGNQ+S ++  TF D   +    Q+    D    R                S    +G   L      ++H    SF        +V  FG+      E+  I+E  ++ W  D F +   ++ +P+  +S+ + +   L + F I+ + F++++T +EN Y KDVP+HN  HAADVTQ+ +VLL A + +NVF+DLEI++ I A  +HDVDHPGV N +L+ TN ++ALMYND SVLENHHL+VAF +L   +CDI  NL+K++RQ+ R+M+I+MVLATD +KHMSLLA LKTMVETKKVA  GSG+L L+NY DR+Q+L+++VHCADLSNPTKPL +YR W +++M+EFFRQGDKER+   +EISPM DR  A++EKSQV FIDF+  PLWETW +LV P+AQD+LDT+E NR+WY SQI K
Sbjct:   37 LVTPFAQILSSLRNVRNTFVTLTNAKKDKQFKHSCFCTSKCSHSFYSWVANSTLDE------------LDWVLYQLETLQTHTSVSEMASNKFKRLLNRELKDFSEANQSGNQVSAWVYNTFTDKQLEVETAQSKTKRDCIRAR----------------SRSMVNGVRKLT-----RLH----SFSG------SVPRFGVEVQNESELATILE-NVNKWDFDAFALGEATNGHPMLAVSYTILQARDLLKIFKIKPTTFINYMTLVENHYLKDVPFHNCIHAADVTQTAHVLLSAQAFDNVFTDLEILSAIIASAVHDVDHPGVNNHFLVATNSEMALMYNDESVLENHHLAVAFQLLQHEDCDIFENLSKQERQTARRMIIEMVLATDNAKHMSLLASLKTMVETKKVAGTGSGVLCLENYTDRMQVLKSLVHCADLSNPTKPLPIYRKWVDRLMEEFFRQGDKERDIDGMEISPMMDRHNASIEKSQVVFIDFVAQPLWETWGELVQPDAQDLLDTIEDNRQWYNSQIPK 525
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO37301 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGA1])

HSP 1 Score: 222.631 bits (566), Expect = 2.188e-64
Identity = 117/288 (40.62%), Postives = 171/288 (59.38%), Query Frame = 2 
Query: 2156 WGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDV-PYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLV 3016
            W  D+F +S   + +PL  I + +  +  +   F I +     F+ ++E  Y +   PYHN  HAADVT + +  L  + +    SDLE+  ++ + IIHD++H G TN + IN+   LAL+YND SVLENHH+S AF +L     +I++ L  +Q    R ++ID VLATDMS H   L  +K  +    VAGS I N        +++Q ++H AD+SNPTK   ++R WT KIM+EFF QGD E E  L++SP+CDR T  + +SQ+ FIDFIV P  E  S+++
Sbjct:   81 WTFDVFALSESCEGHPLRYIGYEVLHRRDMLRNFKIHAMTLDRFLQDVETGYKRHSNPYHNDCHAADVTHTVHYFLECMGVSKYLSDLEVFGLLLSAIIHDLEHTGTTNAFHINSRSDLALLYNDRSVLENHHVSCAFRILQDDEKNILSGLNLEQYADVRSLMIDTVLATDMSSHFEQLRLMKVAL----VAGSPIENR-------EVVQLLLHVADISNPTKDWTIHRQWTTKIMEEFFTQGDMEIELGLDVSPLCDRSTTLIPESQIGFIDFIVSPALEVCSEVL 357
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32142 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVX8])

HSP 1 Score: 201.06 bits (510), Expect = 3.712e-53
Identity = 103/299 (34.45%), Postives = 174/299 (58.19%), Query Frame = 2 
Query: 2156 WGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPN-CDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILN------LDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLE-ISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVY-PE 3025
            W  DI  +   S++ PL  +   +  ++++ EK +I      +++  IE  YH+   YHNSTHAADV  +T V L    ++ V   L+ +A + A I+HDVDHPG TN +L N   +LA++YND +VLE+HH ++AF + +  +  +I +NL  ++ ++ R+ +IDMV+AT+M++H   L+     +  ++ + +   N      L+   +R  I + ++ CAD++NP +P  L + W  +I +E+F Q D+E+ + L  + P+ DR T  V +SQV FID+ V  L++ W    Y PE
Sbjct:  523 WDFDILKLEKASNHRPLYFLGLKILNRFRVCEKLNISEDYVKNWLQLIEANYHRKNAYHNSTHAADVLHATAVFLAKERVKAVLEPLDEVASLIAAIVHDVDHPGYTNSFLCNAGSELAILYNDIAVLESHHAALAFKLTARDDKSNIFSNLDVEEFRTVRQAIIDMVMATEMTRHFEHLSKFVNSINKRRSSSTPDSNTSTSTALNTPENRTLIKRMLIKCADIANPARPRYLCKEWAYRIAEEYFSQTDEEKRRGLPVVMPVFDRATCNVPRSQVWFIDYFVSDLYDAWDAFAYVPE 821
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO43748 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXZ4])

HSP 1 Score: 174.866 bits (442), Expect = 8.501e-48
Identity = 113/349 (32.38%), Postives = 178/349 (51.00%), Query Frame = 2 
Query: 2111 RNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLL-------------------------------GAL-----------------SLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVL-SLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSD 3010
            R+ E+T +++   D W   IF        N L  +S+ +F+    FE F I    FL++   +E+ YH  +PYHNS HA+DV Q    L                                G L                 +L +V   LE++++  A  +HD DHPG TN +L+ T    AL+YND SVLENHH + AFT+L S P  + +  L+  + + FR + I+ +LATD+ +H  +L+D        K A  G+ N D+  DR+  LQ  +  +D+S P+K  +++  WTE+I++EF+ QGD ER + + +SP  DR+   V + Q SFI+ +V PL+ ++++
Sbjct:   12 RSEELTRLMDKVTD-WNFPIF--DACEHGNILVQVSYRIFQNAGFFEIFKIPERKFLNYFFALESGYHS-IPYHNSIHASDVLQGVYFLTTAKIPGFCPPGTPQKLGDNESDSDSDSGITSGVLGEGEEDKKDDDGGGDYGALVDVIPLLELLSLYTAAAMHDYDHPGRTNAFLVATLSHQALLYNDRSVLENHHAAAAFTLLMSDPKYNFLCELSPAEFKRFRFLAIEAILATDLKRHFDILSDFNA-----KTAEGGV-NWDSEADRLLTLQFCIKMSDISGPSKRRDIHTLWTERIVEEFYEQGDDERARGMAVSPYMDRQQPHVAQLQDSFINHLVAPLYNSYAN 350
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVS5])

HSP 1 Score: 158.688 bits (400), Expect = 4.358e-41
Identity = 79/256 (30.86%), Postives = 146/256 (57.03%), Query Frame = 2 
Query: 2306 KYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQD-ILDTLEKNREWY 3070
            +++   P+HN  HA  VTQ    L+    + N  +  +++ ++ + + HD+DHPG  N Y IN   +LAL YND S LENHH +VAF ++     +I+ N++ +  +  R+ +I  +L+TDM++H  +L   K ++++           D+   +  ++Q M+  +D+SN  +P+++   W + ++QEFF Q D E+ + L ++P  DR+  T   +Q+ FI F++ PL+E   +L +P  +D I+  + K  ++Y
Sbjct:  217 RHYNPTPFHNFRHAFCVTQMMYGLIWLTEIFNKITKQDLLIMLTSALCHDLDHPGYNNAYQINARTELALRYNDISPLENHHCAVAFDIMKQDKSNILQNVSAETFKKIREGMIKCILSTDMARHSDILNKFKELLKSG-------FKFDDEAHKSMLMQIMIKVSDVSNEARPMDVAEPWLDCLLQEFFIQSDVEKLEGLPVAPFMDRDKVTKPSAQIGFIKFVLVPLFEALGEL-FPILEDHIVSPVRKALDYY 464
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 532.717 bits (1371), Expect = 3.386e-174
Identity = 289/546 (52.93%), Postives = 383/546 (70.15%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            + SR  S+    H DD+IVTPFAQ+LASLR VR NF  +TNVQ  R +   S   +   +         +++ + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S++I +TFLD                        + E++  +   + E+     P S IS   +  H  +++         N+  FG+ +    E+ + +E  ++ WG+++F ++  S N PLTV+   +F++  L + F I    F++++  +E+ YH DV YHN+ HAADVTQST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LI+TN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFF QGD+ERE+ +EISPMCD+  A+VEKSQV FID+I HPLWETW+DLV+P+AQDILDTLE NREWY S I +
Sbjct:   80 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFT---EEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDK-----------------------QHEVEMPTPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNS-------NIPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 591
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 531.561 bits (1368), Expect = 9.279e-174
Identity = 289/546 (52.93%), Postives = 383/546 (70.15%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            + SR  S+    H DD+IVTPFAQ+LASLR VR NF  +TNVQ  R +   S   +   +         +++ + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S++I +TFLD                        + E++  +   + E+     P S IS   +  H  +++         N+  FG+ +    E+ + +E  ++ WG+++F ++  S N PLTV+   +F++  L + F I    F++++  +E+ YH DV YHN+ HAADVTQST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LI+TN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFF QGD+ERE+ +EISPMCD+  A+VEKSQV FID+I HPLWETW+DLV+P+AQDILDTLE NREWY S I +
Sbjct:   83 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFT---EEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLD-----------------------KQHEVEMPTPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNS-------NIPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 594
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 532.717 bits (1371), Expect = 4.614e-173
Identity = 289/546 (52.93%), Postives = 383/546 (70.15%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            + SR  S+    H DD+IVTPFAQ+LASLR VR NF  +TNVQ  R +   S   +   +         +++ + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S++I +TFLD                        + E++  +   + E+     P S IS   +  H  +++         N+  FG+ +    E+ + +E  ++ WG+++F ++  S N PLTV+   +F++  L + F I    F++++  +E+ YH DV YHN+ HAADVTQST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LI+TN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFF QGD+ERE+ +EISPMCD+  A+VEKSQV FID+I HPLWETW+DLV+P+AQDILDTLE NREWY S I +
Sbjct:  145 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFT---EEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLD-----------------------KQHEVEMPTPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNS-------NIPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 656
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 531.946 bits (1369), Expect = 7.976e-173
Identity = 289/546 (52.93%), Postives = 383/546 (70.15%), Query Frame = 2 
Query: 1454 AASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            + SR  S+    H DD+IVTPFAQ+LASLR VR NF  +TNVQ  R +   S   +   +         +++ + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S++I +TFLD                        + E++  +   + E+     P S IS   +  H  +++         N+  FG+ +    E+ + +E  ++ WG+++F ++  S N PLTV+   +F++  L + F I    F++++  +E+ YH DV YHN+ HAADVTQST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LI+TN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFF QGD+ERE+ +EISPMCD+  A+VEKSQV FID+I HPLWETW+DLV+P+AQDILDTLE NREWY S I +
Sbjct:  141 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFT---EEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLD-----------------------KQHEVEMPTPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNS-------NIPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 652
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 532.332 bits (1370), Expect = 8.594e-173
Identity = 289/544 (53.12%), Postives = 382/544 (70.22%), Query Frame = 2 
Query: 1460 SRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAP-SLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISK 3088
            SR  S+    H DD+IVTPFAQ+LASLR VR NF  +TNVQ  R +   S   +   +         +++ + L  ETLEEL+WCL++LE++QT  SVS+MAS+KFK++LN+EL+  ++ S+SGNQ+S++I +TFLD                        + E++  +   + E+     P S IS   +  H  +++         N+  FG+ +    E+ + +E  ++ WG+++F ++  S N PLTV+   +F++  L + F I    F++++  +E+ YH DV YHN+ HAADVTQST+VLL   +LE VF+DLEI+A IFA  IHDVDHPGV+NQ+LI+TN +LALMYND+SVLENHHL+V F +L   NCDI  NLTKKQRQS RKMVID+VLATDMSKHM+LLADLKTMVETKKV  SG+L LDNY+DRIQ+LQNMVHCADLSNPTKPL LYR WT++IM+EFF QGD+ERE+ +EISPMCD+  A+VEKSQV FID+I HPLWETW+DLV+P+AQDILDTLE NREWY S I +
Sbjct:  155 SRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFT---EEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLD-----------------------KQHEVEMPTPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNS-------NIPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 664
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000032148.1 (SMESG000032148.1)

HSP 1 Score: 1315.44 bits (3403), Expect = 0.000e+0
Identity = 695/695 (100.00%), Postives = 695/695 (100.00%), Query Frame = 2 
Query: 1034 MFNCCGSKQEHSNERNPDLIEHNKLGLNQELXXXXXXXXXERMPTKSPGFHVLSPGSLKFFKKRGXXXXXXXXXXXXXXQTHFDHLIPVQPELVSNTFSKSDESENLDSLGNLPFGDWNKIGLKTSSNVVVDHSVPTTTVAASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            MFNCCGSKQEHSNERNPDLIEHNKLGLNQELKPSSSKKSKERMPTKSPGFHVLSPGSLKFFKKRGKIKSNENCSKSSNSQTHFDHLIPVQPELVSNTFSKSDESENLDSLGNLPFGDWNKIGLKTSSNVVVDHSVPTTTVAASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSLTMETLEELEWCLERLESMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE
Sbjct:    1 MFNCCGSKQEHSNERNPDLIEHNKLGLNQELKPSSSKKSKERMPTKSPGFHVLSPGSLKFFKKRGKIKSNENCSKSSNSQTHFDHLIPVQPELVSNTFSKSDESENLDSLGNLPFGDWNKIGLKTSSNVVVDHSVPTTTVAASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSLTMETLEELEWCLERLESMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 695
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000032148.1 (SMESG000032148.1)

HSP 1 Score: 1052.35 bits (2720), Expect = 0.000e+0
Identity = 545/550 (99.09%), Postives = 546/550 (99.27%), Query Frame = 2 
Query: 1469 GSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 3118
            G  + F HSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSLTMETLEELEWCLERLESMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE
Sbjct:   64 GEPHAFAHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDDSQRSLTMETLEELEWCLERLESMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE 613
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000077093.1 (SMESG000077093.1)

HSP 1 Score: 588.571 bits (1516), Expect = 0.000e+0
Identity = 308/552 (55.80%), Postives = 403/552 (73.01%), Query Frame = 2 
Query: 1451 VAASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREAR--FGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIEN-------VSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQ 3079
            VA SRRGSLYIFR++DD+I+TPFAQILASLR VRANF+LITN+ S+ E +    SI++               +S   +  ETL ELEWCL RLE++QTHRSVSDMAS+KFK+I+N+ELSQ+AD SKSG+QISDYIC TFLD+  D+S+ + S +E     R+G  + E         S +    +   + N    +    ++   +    EN       V   G++     E+++I+++ L  WGM++F  + ++ + PL V+S+ +F+   L  KF I S   + F+ + E  Y   VPYHN+ HAADVTQS NVLL   +LENVFSDLEI++VIFA IIHD+DHPGVTNQYL+NTN++LA +YND SVLENHHL++AF++L+   CD +  L+K+ RQS R+MVIDMVLATDMSKHM+LLADLKTMVETKKVAGSGIL LD Y DRIQILQN+VHCADLSNPTKPL++Y+ W +++M+EF+ QGDKERE  LEISPMCDR+TA++EKSQVSFIDFIVHPLWETWS+LVYP+ Q +L+ LE+NR++YF++
Sbjct:  139 VATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKFE-----SVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNK 685
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000077093.1 (SMESG000077093.1)

HSP 1 Score: 588.186 bits (1515), Expect = 0.000e+0
Identity = 308/552 (55.80%), Postives = 403/552 (73.01%), Query Frame = 2 
Query: 1451 VAASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREAR--FGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIEN-------VSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQ 3079
            VA SRRGSLYIFR++DD+I+TPFAQILASLR VRANF+LITN+ S+ E +    SI++               +S   +  ETL ELEWCL RLE++QTHRSVSDMAS+KFK+I+N+ELSQ+AD SKSG+QISDYIC TFLD+  D+S+ + S +E     R+G  + E         S +    +   + N    +    ++   +    EN       V   G++     E+++I+++ L  WGM++F  + ++ + PL V+S+ +F+   L  KF I S   + F+ + E  Y   VPYHN+ HAADVTQS NVLL   +LENVFSDLEI++VIFA IIHD+DHPGVTNQYL+NTN++LA +YND SVLENHHL++AF++L+   CD +  L+K+ RQS R+MVIDMVLATDMSKHM+LLADLKTMVETKKVAGSGIL LD Y DRIQILQN+VHCADLSNPTKPL++Y+ W +++M+EF+ QGDKERE  LEISPMCDR+TA++EKSQVSFIDFIVHPLWETWS+LVYP+ Q +L+ LE+NR++YF++
Sbjct:  141 VATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKFE-----SVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNK 687
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BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000077093.1 (SMESG000077093.1)

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 298/546 (54.58%), Postives = 393/546 (71.98%), Query Frame = 2 
Query: 1469 GSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREAR--FGSISASSHTLRSEDLKIEGDDSQRSXXXXXXXXXXXXXXXXXSMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIEN-------VSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKXXXXXXXXXXXXTEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQ 3079
            G L    ++DD+I+TPFAQILASLR VRANF+LITN+ S+ E +    SI++               +S   +  ETL ELEWCL RLE++QTHRSVSDMAS+KFK+I+N+ELSQ+AD SKSG+QISDYIC TFLD+  D+S+ + S +E     R+G  + E         S +    +   + N    +    ++   +    EN       V   G++     E+++I+++ L  WGM++F  + ++ + PL V+S+ +F+   L  KF I S   + F+ + E  Y   VPYHN+ HAADVTQS NVLL   +LENVFSDLEI++VIFA IIHD+DHPGVTNQYL+NTN++LA +YND SVLENHHL++AF++L+   CD +  L+K+ RQS R+MVIDMVLATDMSKHM+LLADLKTMVETKKVAGSGIL LD Y DRIQILQN+VHCADLSNPTKPL++Y+ W +++M+EF+ QGDKERE  LEISPMCDR+TA++EKSQVSFIDFIVHPLWETWS+LVYP+ Q +L+ LE+NR++YF++
Sbjct:  119 GYLSEIGNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKFE-----SVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNK 659
The following BLAST results are available for this feature:
BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PDE4C5.132e-17752.84phosphodiesterase 4C [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE4D2.097e-17652.77phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE4D2.881e-17652.77phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE4D4.817e-17652.77phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE4C5.183e-17652.84phosphodiesterase 4C [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde-45.169e-17252.18Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-45.994e-17052.39Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-46.070e-17051.25Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-49.886e-17051.25Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-41.278e-16952.39Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
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BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnc1.856e-17855.04gene:FBgn0000479 transcript:FBtr0070518[more]
dnc1.856e-17855.04gene:FBgn0000479 transcript:FBtr0333312[more]
dnc3.416e-17855.04gene:FBgn0000479 transcript:FBtr0070521[more]
dnc7.122e-17855.04gene:FBgn0000479 transcript:FBtr0070517[more]
dnc8.092e-17855.04gene:FBgn0000479 transcript:FBtr0333314[more]
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BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde4d7.849e-18053.62phosphodiesterase 4D, cAMP-specific [Source:ZFIN;A... [more]
pde4d1.903e-17953.62phosphodiesterase 4D, cAMP-specific [Source:ZFIN;A... [more]
BX510928.23.379e-17953.75phosphodiesterase 4D, cAMP-specific [Source:NCBI g... [more]
pde4ca2.660e-17253.78phosphodiesterase 4C, cAMP-specific a [Source:ZFIN... [more]
pde4ca2.893e-17253.78phosphodiesterase 4C, cAMP-specific a [Source:ZFIN... [more]
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BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PDE4D5.063e-17854.78phosphodiesterase 4D [Source:NCBI gene;Acc:1004964... [more]
PDE4D7.078e-17852.68phosphodiesterase 4D [Source:NCBI gene;Acc:1004964... [more]
PDE4D8.504e-17852.68phosphodiesterase 4D [Source:NCBI gene;Acc:1004964... [more]
PDE4D1.041e-17752.68phosphodiesterase 4D [Source:NCBI gene;Acc:1004964... [more]
PDE4D1.080e-17752.61phosphodiesterase 4D [Source:NCBI gene;Acc:1004964... [more]
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BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pde4d5.127e-17753.13phosphodiesterase 4D, cAMP specific [Source:MGI Sy... [more]
Pde4d2.029e-17653.13phosphodiesterase 4D, cAMP specific [Source:MGI Sy... [more]
Pde4d2.483e-17653.13phosphodiesterase 4D, cAMP specific [Source:MGI Sy... [more]
Pde4d3.306e-17653.13phosphodiesterase 4D, cAMP specific [Source:MGI Sy... [more]
Pde4d4.110e-17653.13phosphodiesterase 4D, cAMP specific [Source:MGI Sy... [more]
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BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8IRU4|PDE4E_DROME3.424e-17755.04cAMP-specific 3',5'-cyclic phosphodiesterase, isof... [more]
sp|Q01063|PDE4D_MOUSE2.875e-17553.13cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS... [more]
sp|Q08493|PDE4C_HUMAN5.526e-17552.84cAMP-specific 3',5'-cyclic phosphodiesterase 4C OS... [more]
sp|Q9W4S9|PDE4C_DROME6.385e-17454.58cAMP-specific 3',5'-cyclic phosphodiesterase, isof... [more]
sp|Q08499|PDE4D_HUMAN6.749e-17452.96cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS... [more]
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BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3KF730.000e+057.14Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC... [more]
A0A4S2M0L30.000e+053.85Phosphodiesterase (Fragment) OS=Opisthorchis felin... [more]
A0A2C9KA620.000e+056.10Phosphodiesterase OS=Biomphalaria glabrata OX=6526... [more]
A0A1S3KF580.000e+057.64Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC... [more]
A0A1S3KFW40.000e+057.64Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC... [more]
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BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde4cb1.007e-17453.51phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
pde4cb1.140e-17453.51phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
pde4cb1.575e-17453.51phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
pde4cb2.474e-17454.24phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
pde4cb2.652e-17452.98phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000007435.14.023e-10373.89pep scaffold:Pmarinus_7.0:GL486982:1709:8825:-1 ge... [more]
pde4ba4.901e-8444.50phosphodiesterase 4B, cAMP-specific a [Source:ZFIN... [more]
ENSPMAT00000007498.18.579e-7576.22pep scaffold:Pmarinus_7.0:GL486417:1684:4657:1 gen... [more]
PDE1C2.099e-6040.41phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:... [more]
pde1a2.411e-6036.99phosphodiesterase 1A, calmodulin-dependent [Source... [more]
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BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PDE24.185e-1328.10High-affinity cyclic AMP phosphodiesterase; compon... [more]
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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO461331.578e-14946.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO373012.188e-6440.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO321423.712e-5334.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO437488.501e-4832.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO321794.358e-4130.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde4d3.386e-17452.93phosphodiesterase 4D [Source:NCBI gene;Acc:1011677... [more]
pde4d9.279e-17452.93phosphodiesterase 4D [Source:NCBI gene;Acc:1011677... [more]
pde4d4.614e-17352.93phosphodiesterase 4D [Source:NCBI gene;Acc:1011677... [more]
pde4d7.976e-17352.93phosphodiesterase 4D [Source:NCBI gene;Acc:1011677... [more]
pde4d8.594e-17353.13phosphodiesterase 4D [Source:NCBI gene;Acc:1011677... [more]
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BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000032148.10.000e+0100.00SMESG000032148.1[more]
SMESG000032148.10.000e+099.09SMESG000032148.1[more]
SMESG000077093.10.000e+055.80SMESG000077093.1[more]
SMESG000077093.10.000e+055.80SMESG000077093.1[more]
SMESG000077093.10.000e+054.58SMESG000077093.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033910 ID=SMED30033910|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=3678bp
ATAAAGCCCCTATTCAATTTTTGTCTTAACAATAAAAATCAGCGAAAGAC
AAAAATCACTTAAGTGTAATCTATTAATGGTAGAGAAATTCTTCTAATCT
GTGCCACTGCCATTGCTACTGCTTCTGCTGCTGCGGAGGCTGCTGCTGCA
ACTGCATATGACGTTCGTATTAATATTAAAAACTGCAAATAAACCGTTTA
CTGTTGCTGAAAGTAGTGTCAGTATTAGTAATCAATAACTACCAAAAGAA
AAAAACGGAGAAAAATAAAAAATTGAAAATTTTTGAATGTTGGACTCAGG
CAATAGCAATAGATGGAGAAATAATAGCCCATCGTAATAGAAAGTAGTAG
AAAGGAGAAAGAATGAAAACCAGTAAAAACCTATTCAAAATAATGAAGCA
TTTATCGCTGTCAATATTAGCAATTAATCGGACTGTCATTGTCAGGCTTG
ATGATTTGACAGCTTGTGATTTCAAAATAAAAAAACTAGAAGTTAAGCAT
ATTGTAGAAAATAACTGAAAGCGTGTTACTTCAATAATTATTATAATACC
TTCATTAGACGGCTCTTAGCAACGGTTATGTCCGATTCTACATCCAATCA
ACATCAACCGTAAACTGACAATTGTGGAGTTTTTTTTTATATTTATGCTT
TCATAATTTAACTTTAAAAAAGAAAATCAGAGCTGAAATTCGTCTTTTTT
CTCCAAACAATTCCACAATTCATTTGCATCATCATAAATTGAAAGCCTGT
GATTGGATAGAGTTTCCACCAATAGGAATTTTCTCATTATATTAACAATA
CTATAAGCATTAAGAAATTATTGATTTATTTTGTTTTTTTTCAAAAAAAA
ATTTTGGTATTCAACTGAGTTCGTTGTTTTGTTTTTGTGGTGGTTTTTAT
TCAATTTTTGAATTTTTTTTTATTCAATGGAATTTTGATTTGAGAATCTG
GAAATATTAAATTGTTTGATTTGGAAAATTATCGATGACATCTGTGGATT
GTATTTTGTGAAATTTGTTTTCCTTACAATCAAATGTTCAATTGCTGTGG
ATCGAAACAGGAACATAGCAATGAAAGGAATCCGGATTTGATAGAACACA
ATAAGTTAGGCTTGAATCAAGAACTGAAACCAAGTAGTTCGAAGAAATCG
AAAGAAAGAATGCCAACGAAATCGCCGGGATTTCATGTGTTGTCGCCGGG
TAGTTTGAAATTCTTTAAAAAACGCGGTAAAATAAAATCCAATGAAAACT
GTTCAAAATCCTCGAATTCACAGACACATTTCGATCATTTGATCCCGGTT
CAGCCGGAACTGGTTAGTAATACGTTCTCGAAATCCGATGAGTCGGAAAA
TCTTGACAGTTTGGGTAATTTACCGTTTGGTGATTGGAATAAAATCGGTT
TGAAAACAAGCTCAAATGTTGTCGTTGATCATAGTGTTCCCACTACTACT
GTTGCAGCTTCACGACGTGGATCATTGTATATTTTCAGACATTCTGACGA
CCTAATCGTCACACCATTCGCCCAAATATTGGCCAGCCTCCGAAACGTAC
GTGCCAACTTCATTCTTATTACAAACGTTCAGAGTTCCAGGGAAGCAAGG
TTCGGTTCAATAAGTGCATCCAGCCACACTTTGCGAAGCGAAGATTTGAA
AATAGAAGGAGATGACAGTCAGCGGAGTCTGACAATGGAGACCTTGGAAG
AATTAGAGTGGTGCTTAGAGCGCTTGGAGAGCATGCAAACTCATCGTTCT
GTTAGTGATATGGCATCAAGCAAATTCAAAAAGATTCTTAATAAAGAATT
GAGTCAATACGCAGATCAATCCAAATCAGGTAATCAAATCTCAGATTACA
TTTGTACCACATTCCTTGACGCTGACGGAGATAACTCTTTGGATCAAACC
TCAGAATATGAAGATACAGATCCTCCTCGGAGAGGCTCGTCAAGGGAAGA
ATTAGACGAACATTCCGAAACAGACGAATCCGAAAGGTATGCAGATGGTG
CTCCTTCGTTAATCTCCAATGAACATCAGAAAATTCACAAACAAACAATT
TCTTTCAAACCTATTTTCGTCGATATTGAAAACGTTTCAACTTTTGGTAT
CAATAGCACTCGAAATGTCGAAATGACAGAAATAATCGAAACCACTTTGG
ACACTTGGGGCATGGATATATTTTTAGTCAGCACCCTTTCAGACAACAAT
CCTCTAACTGTGATATCATTTGCTTTATTTAGAAAATATAAACTGTTTGA
AAAGTTCTCAATTCAATCATCAATATTTTTGAGTTTCATCACAGAAATCG
AAAACAAATATCACAAAGATGTACCATATCACAACAGTACTCATGCTGCT
GATGTTACCCAGTCCACAAATGTACTTTTGGGGGCATTATCATTGGAGAA
TGTATTTTCTGATCTGGAAATCATGGCCGTGATATTTGCCTGCATCATTC
ATGATGTTGATCATCCGGGTGTTACAAACCAATATCTAATTAATACAAAT
GACCAGTTAGCCCTAATGTACAATGATGCTTCTGTGTTAGAAAATCACCA
TCTGTCCGTTGCATTTACAGTCCTCTCTTTGCCAAACTGTGATATTATTA
CTAATCTTACAAAGAAGCAGCGTCAATCATTCAGAAAAATGGTCATAGAT
ATGGTACTAGCTACAGACATGTCTAAACATATGTCACTTCTCGCAGATCT
GAAAACGATGGTTGAAACAAAAAAAGTGGCAGGATCAGGAATATTGAATC
TAGATAATTACAATGATAGAATTCAGATTTTACAAAATATGGTTCATTGT
GCCGATCTTAGCAACCCGACAAAACCTTTAAATTTGTATAGATCATGGAC
AGAAAAAATCATGCAAGAATTTTTCCGACAGGGTGACAAAGAAAGGGAAA
AGAATTTAGAAATTAGTCCAATGTGTGATCGAGAAACTGCGACTGTCGAA
AAATCGCAAGTGAGTTTCATAGATTTTATAGTTCATCCTCTTTGGGAAAC
TTGGTCGGATCTGGTTTATCCAGAGGCGCAAGATATTCTTGATACTTTGG
AGAAAAACAGAGAATGGTATTTCAGTCAAATATCAAAAATCGAAGATAAG
GACCCCTCAGAGACAGAATAGAAATTATAATTATTATTACTAGTATCATT
TATAAAATTATTATACATTTATTTGACAAAAAACCGAAACTAGATTTATT
GTTTCTCAGATTTTACTAGATGTTAAAATTATGAGACAAGCATAAAAAAT
ATTTTTCTATGAATACGGAACATTTTCCAGAGGAACCTTAATAAAATCTT
GGAGATATTATTTGTGATATATGAAAATTAGACCTACACAAAACGAAATC
TCTACTTTGTTCCCCCTCCCCTCCTACTCTTCCCTCCAAAATTAAAACAC
TATTTGCTAGCTCATCGTGATTTTTATTTGTTTAAAAATACAACCGACAA
TCATGTAAAAGATTGTGAAATTATCTTATATTTGTATGTAATTTGTGTTT
TGAAAATCGTGCATTGAATTTGTCGAAACTTTGTCACGGAAATATTTGAT
TTGATTTCTTTTGGTCGAGAAACATTACCTTTCACCAAATTTAGAACGAT
TTTTTGTTTTTCTATTTTAACATCTGTTGATCTACTAGTTTTGTTGATAT
TGAATTTATGAAATTGGTTTTCTATAAA
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protein sequence of SMED30033910-orf-1

>SMED30033910-orf-1 ID=SMED30033910-orf-1|Name=SMED30033910-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=696bp
MFNCCGSKQEHSNERNPDLIEHNKLGLNQELKPSSSKKSKERMPTKSPGF
HVLSPGSLKFFKKRGKIKSNENCSKSSNSQTHFDHLIPVQPELVSNTFSK
SDESENLDSLGNLPFGDWNKIGLKTSSNVVVDHSVPTTTVAASRRGSLYI
FRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTL
RSEDLKIEGDDSQRSLTMETLEELEWCLERLESMQTHRSVSDMASSKFKK
ILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRR
GSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIEN
VSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFR
KYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLG
ALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDAS
VLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHM
SLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLN
LYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIV
HPLWETWSDLVYPEAQDILDTLEKNREWYFSQISKIEDKDPSETE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR040844PDE4_UCR
IPR036971PDEase_catalytic_dom_sf
IPR023088PDEase
IPR003607HD/PDEase_dom
IPR002073PDEase_catalytic_dom
IPR023174PDEase_CS
Vocabulary: molecular function
TermDefinition
GO:0008081phosphoric diester hydrolase activity
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity
GO:0016787hydrolase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR0230883'5'-cyclic nucleotide phosphodiesterasePRINTSPR00387PDIESTERASE1coord: 428..441
score: 57.43
coord: 604..620
score: 54.12
coord: 473..488
score: 57.5
coord: 500..516
score: 51.41
coord: 587..600
score: 56.14
coord: 459..472
score: 46.0
IPR003607HD/PDEase domainSMARTSM00471hd_13coord: 430..605
e-value: 4.8E-5
score: 32.8
IPR003607HD/PDEase domainCDDcd00077HDccoord: 432..614
e-value: 5.82558E-13
score: 64.6681
IPR040844Phosphodiesterase 4 upstream conserved regions (UCR)PFAMPF18100PDE4_UCRcoord: 159..279
e-value: 8.5E-48
score: 161.9
IPR0369713'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyGENE3DG3DSA:1.10.1300.10coord: 363..695
e-value: 2.3E-138
score: 462.9
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainPFAMPF00233PDEase_Icoord: 432..673
e-value: 6.1E-90
score: 301.1
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainPROSITEPS51845PDEASE_I_2coord: 356..686
score: 136.571
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 292..319
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..47
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 284..327
NoneNo IPR availablePANTHERPTHR11347:SF74CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4Acoord: 141..686
NoneNo IPR availablePANTHERPTHR11347CYCLIC NUCLEOTIDE PHOSPHODIESTERASEcoord: 141..686
NoneNo IPR availableSUPERFAMILYSSF109604HD-domain/PDEase-likecoord: 368..687
IPR0231743'5'-cyclic nucleotide phosphodiesterase, conserved sitePROSITEPS00126PDEASE_I_1coord: 473..484