sec1 family domain-containing protein 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033902 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 1
Homology
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Human
Match: SCFD1 (sec1 family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20726]) HSP 1 Score: 514.227 bits (1323), Expect = 9.349e-175 Identity = 294/655 (44.89%), Postives = 434/655 (66.26%), Query Frame = 2
Query: 41 NLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQT-------------KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
++R R+ ALK MLNFN P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PIPDVPA+YFV+PT ENI+++C+D+ N +YESYY+NFIS I+R KLE +A + + +V Q++K+FDQY NFI LEDD+FVL + +SY ++N +D E++ ++++IVD LF VT+G +P+IRC G AAEMVA +LDKKL++NLRD+RNSLF+G + SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ + K SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEK+ ++ L +KSLLD++S PD GT DK+RL L+ + + +P+ + +L+Q + + +++ + ++ ++ + +S S TK GL ++ ++ + MEGVKN V K+ LP T+IL NLME S+ ETD+++YFDPK+ R D ++PR K+ FQ+AIVFV+GGGNY+EYQNL++Y K + K I YGC+EL N QF+ QLS LG+
Sbjct: 14 SIRERQTVALKRMLNFNVPHIKNSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDTLGA---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDL-TPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTL-DKSLLDIISDPDAGTPEDKMRLFLIYYISTQQAPSEA-------DLEQYKKALTDAGCNLNPLQYIKQWKAFTKMASAPASYG-STTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRGNDS-SVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYIKGKQG-------KHILYGCSELFNATQFIKQLSQLGQ 641
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Human
Match: SCFD1 (sec1 family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20726]) HSP 1 Score: 463.766 bits (1192), Expect = 6.087e-156 Identity = 267/601 (44.43%), Postives = 401/601 (66.72%), Query Frame = 2
Query: 203 LGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI---------PS----QTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
+G+T+ L ++S+R+PIPDVPA+YFV+PT ENI+++C+D+ N +YESYY+NFIS I+R KLE +A + + +V Q++K+FDQY NFI LEDD+FVL + +SY ++N +D E++ ++++IVD LF VT+G +P+IRC G AAEMVA +LDKKL++NLRD+RNSLF+G + SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ P+ + K SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEK+ ++ L +KSLLD++S PD GT DK+RL L+ + + +P+ + +L+Q + + +++ + ++ ++ + +S S TK GL ++ ++ + MEGVKN V K+ LP T+IL NLME S+ ETD+++YFDPK+ R D ++PR K+ FQ+AIVFV+GGGNY+EYQNL++Y K + K I YGC+EL N QF+ QLS LG+
Sbjct: 1 MGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDTLGA---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDL-TPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTL-DKSLLDIISDPDAGTPEDKMRLFLIYYISTQQAPSEA-------DLEQYKKALTDAGCNLNPLQYIKQWKAFTKMASAPASYG-STTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRGNDS-SVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYIKGKQG-------KHILYGCSELFNATQFIKQLSQLGQ 574
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Human
Match: SCFD1 (sec1 family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20726]) HSP 1 Score: 426.787 bits (1096), Expect = 6.283e-142 Identity = 252/576 (43.75%), Postives = 378/576 (65.62%), Query Frame = 2
Query: 278 LPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI---------PS----QTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
+PT ENI+++C+D+ N +YESYY+NFIS I+R KLE +A + + +V Q++K+FDQY NFI LEDD+FVL + +SY ++N +D E++ ++++IVD LF VT+G +P+IRC G AAEMVA +LDKKL++NLRD+RNSLF+G + SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ P+ + K SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEK+ ++ L +KSLLD++S PD GT DK+RL L+ + + +P+ + +L+Q + + +++ + ++ ++ + +S S TK GL ++ ++ + MEGVKN V K+ LP T+IL NLME S+ ETD+++YFDPK+ R D ++PR K+ FQ+AIVFV+GGGNY+EYQNL++Y K + K I YGC+EL N QF+ QLS LG+
Sbjct: 1 MPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDTLGA---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDL-TPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTL-DKSLLDIISDPDAGTPEDKMRLFLIYYISTQQAPSEA-------DLEQYKKALTDAGCNLNPLQYIKQWKAFTKMASAPASYG-STTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRGNDS-SVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYIKGKQG-------KHILYGCSELFNATQFIKQLSQLGQ 549
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Human
Match: SCFD1 (sec1 family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20726]) HSP 1 Score: 217.238 bits (552), Expect = 4.424e-66 Identity = 102/197 (51.78%), Postives = 145/197 (73.60%), Query Frame = 2
Query: 77 MLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVA 667
MLNFN P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PIPDVPA+YFV+PT ENI+++C+D+ N +YESYY+NFIS I+R KLE +A + + +V Q++K+FDQY NFI LEDD+FVL + +SY ++N +D E++ ++++IVD LF VT+G +P+IRC G AAEMVA
Sbjct: 1 MLNFNVPHIKNSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVA 197
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Human
Match: SCFD1 (sec1 family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20726]) HSP 1 Score: 145.976 bits (367), Expect = 4.742e-40 Identity = 69/132 (52.27%), Postives = 99/132 (75.00%), Query Frame = 2
Query: 41 NLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISK 436
++R R+ ALK MLNFN P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PIPDVPA+YFV+PT ENI+++C+D+ N +YESYY+NFIS I+R KLE +A + + +V Q++K
Sbjct: 14 SIRERQTVALKRMLNFNVPHIKNSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAK 145
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Celegans
Match: sly-1 (SLY1 homolog [Source:UniProtKB/TrEMBL;Acc:Q20364]) HSP 1 Score: 438.343 bits (1126), Expect = 1.975e-145 Identity = 278/675 (41.19%), Postives = 403/675 (59.70%), Query Frame = 2
Query: 41 NLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHD-DKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI-PSQTKKTNSYELWC-ENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD---------ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRS-HRLHSQNLSSKQV-SHQ---TKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNL---------------------MEQVSDVETDNFKYFDPKLYRSADGDN-LPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
++R R+I AL+ M+N N P+ + +WKVL+ D+ G DIIS L K LR+LGVT+ L I + REP+ DVPA+YFV P ENI+ + +D+ +Y+S+Y NFISP+ R +LE LA + +V+Q+ K+ DQY NFI LEDDLFVL + + SY ++N G SD ++A+++SI DGLF+VC T+G +P+IRCP GNAAEMVAK+LD+KL+DNLRDSRN+LF+ G+ L RPLLVI DRS DLAT ++H WTYQAL+HD+L + N V I S T K Y++ +D+ W + + P +A+ +Q+ L+ +SKE ++ ++K ++GL G+S+ + D+T KL TV SL LE K+L+++HTNIAT L D IKERKLD+ FELE+KL PL ++ + LS+ + + + L +L + + N DQ+ + + + S + V+ ++S +L S+ +S HQ TK+ +F K +SHS + MEGVKN V K+H LP TK++ +L Q D++ D + +FDPKL + L + S QD I+FV+GGGNYVEYQNL++Y K +++YGCTEL+N QF QL+ LGR
Sbjct: 7 SVRTRQIVALRTMINLNEPVVNSGVREPVWKVLVLDRTGQDIISPLLPVKQLRELGVTLHLLIGARREPLTDVPAVYFVSPNDENIDLMSEDLKKAMYDSFYCNFISPLARPRLESLASAAVHGGAVSQVQKVVDQYLNFISLEDDLFVLRRYSENSTFSYHAMNSPGTSDVAVNAMLDSIADGLFAVCATMGIVPIIRCPKGNAAEMVAKKLDQKLRDNLRDSRNNLFTMDGVR---------MGLLQTSRPLLVIGDRSADLATMLHHTWTYQALMHDVLELDQNRVTISTSSTGKKKDYDMATGGSDKLWNNHKGSAFPTVAEAVQENLDDYRSKEDDIKKIKQALGLSGESEAADEALTNVLADTTAKLGSTVMSLPDLLESKRLIDLHTNIATTLLDVIKERKLDVLFELEQKLLQHSPL-DQPVTQFLSNIN---HQEDVLRVLIIAFLCQETVNQ------NGYDQMMNLLRERGIEESALKHVQKLKSISQLGSRAANSAHTEEHQGAGTKTISMFGKLLSHSSKFVMEGVKNLVPKEHNLPLTKMIDSLNTPPSSTGISSAVGINQMIGGSSQGPDID-DIYCFFDPKLMHQPTKETILLARQQSAQDVILFVVGGGNYVEYQNLVDYGKRKN-------LMRVTYGCTELVNPAQFCDQLTRLGR 654
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Celegans
Match: sly-1 (SLY1 homolog [Source:UniProtKB/TrEMBL;Acc:Q20364]) HSP 1 Score: 431.409 bits (1108), Expect = 2.031e-142 Identity = 279/686 (40.67%), Postives = 404/686 (58.89%), Query Frame = 2
Query: 41 NLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHD-DKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI-PSQTKKTNSYELWC-ENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD---------ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRS-HRLHSQNLSSKQV-SHQ---TKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNL---------------------MEQVSDVETDNFKYFDPKLYRSADGDN-LPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGRN*CELRCLLKD 1981
++R R+I AL+ M+N N P+ + +WKVL+ D+ G DIIS L K LR+LGVT+ L I + REP+ DVPA+YFV P ENI+ + +D+ +Y+S+Y NFISP+ R +LE LA + +V+Q+ K+ DQY NFI LEDDLFVL + + SY ++N G SD ++A+++SI DGLF+VC T+G +P+IRCP GNAAEMVAK+LD+KL+DNLRDSRN+LF+ G+ L RPLLVI DRS DLAT ++H WTYQAL+HD+L + N V I S T K Y++ +D+ W + + P +A+ +Q+ L+ +SKE ++ ++K ++GL G+S+ + D+T KL TV SL LE K+L+++HTNIAT L D IKERKLD+ FELE+KL PL ++ + LS+ + + + L +L + + N DQ+ + + + S + V+ ++S +L S+ +S HQ TK+ +F K +SHS + MEGVKN V K+H LP TK++ +L Q D++ D + +FDPKL + L + S QD I+FV+GGGNYVEYQNL++Y K +++YGCTEL+N QF Q+S C L L D
Sbjct: 7 SVRTRQIVALRTMINLNEPVVNSGVREPVWKVLVLDRTGQDIISPLLPVKQLRELGVTLHLLIGARREPLTDVPAVYFVSPNDENIDLMSEDLKKAMYDSFYCNFISPLARPRLESLASAAVHGGAVSQVQKVVDQYLNFISLEDDLFVLRRYSENSTFSYHAMNSPGTSDVAVNAMLDSIADGLFAVCATMGIVPIIRCPKGNAAEMVAKKLDQKLRDNLRDSRNNLFTMDGVR---------MGLLQTSRPLLVIGDRSADLATMLHHTWTYQALMHDVLELDQNRVTISTSSTGKKKDYDMATGGSDKLWNNHKGSAFPTVAEAVQENLDDYRSKEDDIKKIKQALGLSGESEAADEALTNVLADTTAKLGSTVMSLPDLLESKRLIDLHTNIATTLLDVIKERKLDVLFELEQKLLQHSPL-DQPVTQFLSNIN---HQEDVLRVLIIAFLCQETVNQ------NGYDQMMNLLRERGIEESALKHVQKLKSISQLGSRAANSAHTEEHQGAGTKTISMFGKLLSHSSKFVMEGVKNLVPKEHNLPLTKMIDSLNTPPSSTGISSAVGINQMIGGSSQGPDID-DIYCFFDPKLMHQPTKETILLARQQSAQDVILFVVGGGNYVEYQNLVDYGKRKN-------LMRVTYGCTELVNPAQFCDQVSC-----CSLSLPLTD 660
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Celegans
Match: T07A9.10 (pep chromosome:WBcel235:IV:390512:393158:1 gene:WBGene00020298.1 transcript:T07A9.10.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T07A9.10) HSP 1 Score: 89.3521 bits (220), Expect = 2.367e-18 Identity = 83/333 (24.92%), Postives = 146/333 (43.84%), Query Frame = 2
Query: 98 ITKVVNYD-----KLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGI-------YESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPP--GNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWC-ENDEFWRDERHKPLPEIADVIQQGLEVIKSKEK 1051
I + NYD + + VL+ DK + ++++ + + + GVT+ ++ REP+P + AIY + P +E+I+ L D Y S +I F+ P E E+L+ +S +V I + + N +E +F ++ G M+ ++ DG+ S+C T+ P +R ++E+ + K + F GM T ++ LV+LDRS DL +P+ H T QA+V D+ K + T+ +S E+ E D+ W D RHK LPE+ + + ++ K+ K
Sbjct: 14 ILRPQNYDSKLGHRKFSVLVLDKSAMVVVNSCLSLNEVFEEGVTLVEDLTRNREPMPSMDAIYIISPVAESIDILINDFSRKTKFNPGNSYRSAHIFFLDPCCDELFEKLS----KSPAVKWIKTLKELNLNLKPVESQIFTVNSQFRGDMTKTA-------------------DGIVSLCATLNIHPTLRFQSDFAQSSEICQRVEQKLKE----------FGNEGMGTDAE---------------LVVLDRSFDLVSPLLHEVTLQAMVVDVTAFK---DGVYRYTEAGDSKEIVLDEKDQNWLDLRHKLLPEVMKSVNKMVKDFKNTNK 295
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Celegans
Match: unc-18 (Putative acetylcholine regulator unc-18 [Source:UniProtKB/Swiss-Prot;Acc:P34815]) HSP 1 Score: 89.3521 bits (220), Expect = 2.759e-18 Identity = 73/304 (24.01%), Postives = 138/304 (45.39%), Query Frame = 2
Query: 128 WKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKD-IDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYE--LWCENDEFWRDERHKPLPEIADVIQQGLE 1030
W VLI D + ++S+ ++ + G+TI ++N REP+P + AIY + PT+E+I+KL +D +Y+ ++ F + +QL + +S + I + + F E +F L T + Y++ G + + + I + + +VC T+G P +R + + + + + L D S G + + R L+I+DR D TP+ H T QA+ +D+L I+ + + N + L END+ W + RHK + ++ + + L+
Sbjct: 28 WNVLIVDTLAMRMLSSCCKMHNIMEEGITIVEDLNKRREPLPTLEAIYLIAPTAESIDKLIQDYCARNLYKCAHVFFTEACS----DQLFSTLSKSAAARFIKTLKEINIAFTPYESQVFNLDSPDTFFLYYNAQKQGG-----LTSNLERIAEQIATVCATLGEYPSLR--------------YRADFERNVELGHLVEQKLDAYKADDPSMGEGADKA--RSQLIIIDRGYDAITPLLHELTLQAMCYDLLGIENDVYKYETGGSDENLEKEVLLDENDDLWVEMRHKHIAVVSQEVTKNLK 306
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Celegans
Match: vps-45 (Related to yeast Vacuolar Protein Sorting factor [Source:UniProtKB/TrEMBL;Acc:H2KYN0]) HSP 1 Score: 62.003 bits (149), Expect = 8.363e-10 Identity = 59/267 (22.10%), Postives = 115/267 (43.07%), Query Frame = 2
Query: 128 WKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSE--REPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGN-AAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQ 919
K+L+ D +S F Q + V I I ++ E I ++ + FV PT +NI +L K++ + YY+ F + IN+ +++LA + ++++V ++ ++F + + + DLF L+ S++ A + I G+ ++ + + P +R + + + VA N LF T L+I++RS D TP+ + WTY+A++H++L + N Q
Sbjct: 22 MKLLLMDGETTPTVSCAFAQSEVMQKEVYIFDRIENKTSSENIKNLKCVVFVRPTPKNIERLVKELQEPRFSQYYLYFTNTINKYDVKRLAEAD-KNETVREVQEVF---LDGVPIRKDLFTLNLTHIFDSSFTLKEEAAE----------RIKCGIIALLLQLKKAPAVRYQKSSPSCKKVA-----DDVAQFIRRENGLFENSRADT-----------------TLLIIERSQDAVTPLLNQWTYEAMIHEMLTLTNNRCTCTDQ 252
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Fly
Match: Slh (gene:FBgn0264978 transcript:FBtr0335169) HSP 1 Score: 484.952 bits (1247), Expect = 1.055e-163 Identity = 271/652 (41.56%), Postives = 428/652 (65.64%), Query Frame = 2
Query: 38 LNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSH---LSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQT------KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDIT-----DSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRS--HRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLG 1945
L LR R+I+A+K MLN NS K + + +WK+LI D+ G DIIS + + K LR+LGVT+ + ++S+R+ IPDVPAIYF LPT EN++++ +D +G+Y+ Y++NF++PI R K+E LA + + V I +++DQY NFI LEDD F+L ++ +SY ++N A D+E++A+++SIVD LF++ VT+G +P+IRCP +AAEMVA++L+KKL++NL D+R +LF H TQ+ SF+RP+L++LDR++DLATP++H W+YQALVHD+L++ N V + +T KK + +L ND FW + P P +A+ IQ+ LE ++ E+E+ +LK+SMG+ G+SDI D+T +L++ V+SL +EKK+L+++HT IAT + + IK R+LD +FE+EEK+ ++Q L L + G A DKLRL ++ + + P + E ++L + ++ D++ +A V+ + +R S + +++ TK+ +FTK +S ++ MEGVKN V K+H LP TKI +ME S+ ETD++ Y DPKL + G+ LP+ ++ FQDA+VF++GGGNY+EYQNL+++ K ++ S+ ++I YG + L N QFL +LS LG
Sbjct: 2 LTLRERQINAIKQMLNLNSQQPKALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRNSAAEMVARKLEKKLRENLWDARANLF----------HMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLVYVEDETASAGARKKPKACDL-DRNDRFWMTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAILNFIKARRLDSFFEIEEKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQQLP--------ESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGGGTKTVSMFTKLVSQGSSFVMEGVKNLVVKRHNLPVTKITEQVMECRSNAETDDYLYLDPKLLKG--GEVLPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQT---SNVQRRIIYGASTLTNARQFLKELSALG 629
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Fly
Match: Slh (gene:FBgn0264978 transcript:FBtr0077782) HSP 1 Score: 484.952 bits (1247), Expect = 1.055e-163 Identity = 271/652 (41.56%), Postives = 428/652 (65.64%), Query Frame = 2
Query: 38 LNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSH---LSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQT------KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDIT-----DSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRS--HRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLG 1945
L LR R+I+A+K MLN NS K + + +WK+LI D+ G DIIS + + K LR+LGVT+ + ++S+R+ IPDVPAIYF LPT EN++++ +D +G+Y+ Y++NF++PI R K+E LA + + V I +++DQY NFI LEDD F+L ++ +SY ++N A D+E++A+++SIVD LF++ VT+G +P+IRCP +AAEMVA++L+KKL++NL D+R +LF H TQ+ SF+RP+L++LDR++DLATP++H W+YQALVHD+L++ N V + +T KK + +L ND FW + P P +A+ IQ+ LE ++ E+E+ +LK+SMG+ G+SDI D+T +L++ V+SL +EKK+L+++HT IAT + + IK R+LD +FE+EEK+ ++Q L L + G A DKLRL ++ + + P + E ++L + ++ D++ +A V+ + +R S + +++ TK+ +FTK +S ++ MEGVKN V K+H LP TKI +ME S+ ETD++ Y DPKL + G+ LP+ ++ FQDA+VF++GGGNY+EYQNL+++ K ++ S+ ++I YG + L N QFL +LS LG
Sbjct: 2 LTLRERQINAIKQMLNLNSQQPKALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRNSAAEMVARKLEKKLRENLWDARANLF----------HMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLVYVEDETASAGARKKPKACDL-DRNDRFWMTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAILNFIKARRLDSFFEIEEKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQQLP--------ESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGGGTKTVSMFTKLVSQGSSFVMEGVKNLVVKRHNLPVTKITEQVMECRSNAETDDYLYLDPKLLKG--GEVLPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQT---SNVQRRIIYGASTLTNARQFLKELSALG 629
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Fly
Match: Vps45 (gene:FBgn0261049 transcript:FBtr0082070) HSP 1 Score: 103.219 bits (256), Expect = 1.106e-22 Identity = 94/341 (27.57%), Postives = 164/341 (48.09%), Query Frame = 2
Query: 131 KVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSER--EPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGN-AAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTV---NIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTV 1135
K+++ DK IIS F+Q + V + ++S R E + + I F+ PT +NI L ++ N Y +YYI F + I R ++ LA +S+SV ++ ++ Y +++C+ +LF S N + DA +N + G+ +V +++ PVIR G+ AA+++AK + +++ S+L D S PLL++LDR D TP+ H WTYQA+VH++L+IK N + N P+ K L + D+F+ + + EI I+Q +E + K + +++S + + K+S TV
Sbjct: 23 KIILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLKYLKCIVFIRPTKQNIQLLANELRNPKYSAYYIYFSNIIPRTDIKYLAECD-ESESVREVKEL---YADYLCVNPNLF----------SLGIPNCMANLNWLPDA-LNRSMQGITAVLLSLKLNPVIRYRAGSQAAQLLAKLIYEQITKE--------------SSLFDFRSNMDGAAP---PLLLVLDRRDDPVTPLLHQWTYQAMVHELLHIKNNRLDLSNCPNVPKDFKELVLSGDQDDFYGNNMYANYGEIGSTIKQLMEEFQRKANDHKKVESIADMKNFIESYPQFKKMSGTV 331
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Fly
Match: Rop (gene:FBgn0004574 transcript:FBtr0310632) HSP 1 Score: 92.4337 bits (228), Expect = 3.453e-19 Identity = 78/320 (24.38%), Postives = 138/320 (43.12%), Query Frame = 2
Query: 128 WKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDN---GIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSM 1078
W+VL+ DK G+ ++S + G+T+ +IN +REP+P + AIY + P+ E++ L +D +N +Y ++ F E L +S + +I + + F+ E +F L T YS + +S I I + + ++C T+G P +R + D D S+ L D + G + R L+ILDR D +P+ H T QA+ +D+L I + + + L END+ W + RH+ + ++ + Q L+ ++ + KSSM
Sbjct: 39 WRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINKKREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLC----KSCAAGKIKTLKEINIAFLPYECQVFSLDSPDTFQCLYSPAFASIRSKH-----IERIAEQIATLCATLGEYPNVR--------------YRSDWDRNIDLAASVQQKLDAYKADDATMGEGPEKA--RSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVNDVYRYTPGPNQPDKEVLLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRMGSADKSSM 333
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Fly
Match: Rop (gene:FBgn0004574 transcript:FBtr0073263) HSP 1 Score: 92.4337 bits (228), Expect = 3.453e-19 Identity = 78/320 (24.38%), Postives = 138/320 (43.12%), Query Frame = 2
Query: 128 WKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDN---GIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSM 1078
W+VL+ DK G+ ++S + G+T+ +IN +REP+P + AIY + P+ E++ L +D +N +Y ++ F E L +S + +I + + F+ E +F L T YS + +S I I + + ++C T+G P +R + D D S+ L D + G + R L+ILDR D +P+ H T QA+ +D+L I + + + L END+ W + RH+ + ++ + Q L+ ++ + KSSM
Sbjct: 39 WRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINKKREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLC----KSCAAGKIKTLKEINIAFLPYECQVFSLDSPDTFQCLYSPAFASIRSKH-----IERIAEQIATLCATLGEYPNVR--------------YRSDWDRNIDLAASVQQKLDAYKADDATMGEGPEKA--RSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVNDVYRYTPGPNQPDKEVLLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRMGSADKSSM 333
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Zebrafish
Match: scfd1 (sec1 family domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-030116-3]) HSP 1 Score: 539.265 bits (1388), Expect = 0.000e+0 Identity = 304/658 (46.20%), Postives = 444/658 (67.48%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI-----------PSQTKKTN--SYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
MA ++R ++ ALK MLNFN+P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PIPDVPAIYF++PT ENI+++C+D+ N +YESYY+NFIS I+R KLE +A + +++VNQ++K+FDQY NFI LEDD+F+L + +SY ++N D +++ I+++IVD LF VT+G +P+IRCP GNAAEMVA +LDKKL++NLRD+RNSLF+G M T SF+RPL V+ DR+LDLATP++H WTYQAL+HD+L+ N V++ ++ KK N SY+L D+FW+ + P PE+A+ +Q+ L+ +++E E+ +LKS MGL G+ D ++D+T KL+ VSSL LEKK+L+++HTN+AT + D IK RKLD+YFE EEKL ++ L +KSLLD++S PD GTA DK+RL L+ + S P + +L+Q + + D+S + ++ ++ + + S K GLF++ ++ + MEGVKN V K+H LP T+IL NLME S+ ETD+++YFDPK+ R ++ ++PR K+ FQ+AIVFV+GGGNY+EYQNL++YTK + K+I YGC+EL N QF+ QLS LG+
Sbjct: 1 MAASIREKQTAALKRMLNFNAPPLKNTTAEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAIYFIMPTEENIDRICQDLRNQLYESYYLNFISAISRSKLEDIASAALAANAVNQVTKVFDQYLNFITLEDDMFILCNQNKEHISYHAINKPDIMDTDMEGIMDTIVDSLFCFFVTLGAVPIIRCPRGNAAEMVAVKLDKKLRENLRDARNSLFTGDTMGT---------GQFSFQRPLFVLADRNLDLATPLHHTWTYQALIHDVLDFHLNRVSVDESHGSEASPAGARPKKKNKKSYDLTAA-DKFWQKHKGSPFPEVAEAVQEELDTYRAQEDEVKRLKSIMGLEGEDDGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLDHIKSRKLDVYFEYEEKLMSKSTL-DKSLLDIISDPDAGTAEDKMRLFLIYYITSQQPPLEA-------DLEQYKKAMVDAGCDLSPLNYIKQWKAFTKMAAT-PANYGSSGVKPMGLFSRVMNTGSQFVMEGVKNLVLKQHNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRGSES-SIPRNKNPFQEAIVFVVGGGNYIEYQNLVDYTKTRQG-------KRILYGCSELFNAAQFIKQLSQLGQ 631
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Zebrafish
Match: vps45 (vacuolar protein sorting 45 homolog [Source:ZFIN;Acc:ZDB-GENE-060503-526]) HSP 1 Score: 103.99 bits (258), Expect = 9.176e-23 Identity = 140/577 (24.26%), Postives = 253/577 (43.85%), Query Frame = 2
Query: 131 KVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSE-REPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFER----PLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVN---IPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLE-VIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLH---EKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYF--MEGVKNFVAKKHKLPFTKILHNLMEQV--SDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVE 1813
KVL+ DK I+S ++TQ + V + I+S+ R+ + + AI F+ PT EN+ L +++ Y Y+I F + I++ +++ LA ++D ++++ + Y +FI + LF L+ L G + +++ + GL SV +++ P+IR +S S ++ + F + PLL+ILDRS D TP+ + WTYQA+VH++L + N ++ +P +K L ENDEF+ + + EI I+ +E K K K+ +L+S + + K+S TVS H + L+ + ER+L E+E++L A Q H ++ L +L SP + D +RL++L L ++ + + ++ + S H ++ AV R+ +L + T +S ++ +F ++GV+N V +H+ +LH+ ++Q+ ++ F Y P L+ QD IVF+IGG Y E
Sbjct: 23 KVLLMDKETTSIVSVVYTQSEILQKEVYLFERIDSQNRDNMKHLKAICFLRPTKENVEHLIQELRRPKYSVYFIYFSNVISKSEVKALA----EADEQEVVAEVQEFYGDFIAVNPHLFSLN-----------LQGVSRGRSWEPSVLPRVTQGLTSVLLSLKKCPMIRY-----------------------QLSSDMSKRLAESVKQIITKEYELFDFRKTEVPPLLLILDRSDDAITPLLNQWTYQAMVHELLGLNNNRIDLSRVPGISKDLREVVLSAENDEFYANNLYLNFGEIGTNIKNLMEDFQKKKPKDQQKLESISDMKAFVENYPQFKKMSGTVSK-------------HVTVVGELSRLVSERQLMEVSEVEQEL-ACQNDHSNAQQMLRRLLQSPRLSEIDAVRLVMLYALRYEKHSSSILPSLMEELNRKGVSERHR-----KMVHAVVEYGGKRIRGSDLITP------------TDAVSITKQFFKGLKGVEN-VYTQHQ----PLLHDTLDQLIKGRLKDSQFPYLGPS-----------SLRDRPQDIIVFIIGGATYEE 514
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Zebrafish
Match: stxbp3 (syntaxin binding protein 3 [Source:ZFIN;Acc:ZDB-GENE-040426-2833]) HSP 1 Score: 90.8929 bits (224), Expect = 1.536e-18 Identity = 78/335 (23.28%), Postives = 142/335 (42.39%), Query Frame = 2
Query: 122 KLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDID-NGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIR----CPPGNA---AEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDI 1102
K W +LI D ++S+ L G+++ N+ REP+PD+ AIYF+ PT E I+ D Y++ Y+ F E +++ + + I K + +F+ E +F + + YS + Q+ + ++ I D + ++C T+ P +R PG AE+V N L + ++ T + L+I+DR++D +PI H TYQA+ +D++ I N + + L E+DE W RH+ + E+ + I + ++ I + E Q + +G S +
Sbjct: 26 KKWNILILDDFTTRLLSSCCKMSDLMSEGISVLENLFKNREPVPDMKAIYFMAPTVECIDAFINDFKPKPKYKAAYVFFTDYCPDELFDKM-----KKNCAKHIKKCKEINISFLPQEAQVFTCENPEAFKKIYSGFS------QDREKTLDKIADQIVTLCATLDEYPGVRYKRESTPGYGKMLAELV---------------DNKLARHYELDEITTKKEKTPAQ-------LLIVDRAMDPVSPILHELTYQAMAYDLIPIN-NNIYEYKMKDGSKKEALLNEDDELWVKLRHRHIAEVTEQIPKLVKDISASRDEKQQGDGKITIGALSQL 326
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Zebrafish
Match: stxbp1b (syntaxin binding protein 1b [Source:ZFIN;Acc:ZDB-GENE-060531-166]) HSP 1 Score: 83.9593 bits (206), Expect = 2.045e-16 Identity = 77/323 (23.84%), Postives = 143/323 (44.27%), Query Frame = 2
Query: 128 WKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLC---KDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI--PSQTKKTNSYE-LWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSM 1078
WKVL+ DK + ++S+ + G+TI +I +REP+P + AI+ + P+ E++ L +D N IY ++ F I + L L + S S+ +++I + F+ E +F + YS K + ++ + + + ++C T+ P +R V ++ + D + +L G + R L+ILDR D +P+ H T+QA+ +D+L I+ N V + S T E L E+D+ W RHK + E++ + + L+ + +K K++M
Sbjct: 28 WKVLVVDKLSMRMVSSCCKMTDIMSEGITIVEDITKKREPLPTMEAIFLITPSDESVEGLINDFRDPRNPIYRGAHVFFTDAIP-DSLFNLLSKSRASKSIKTLTEI---HIAFLPYESQVFSVDKSDAFQDFYSPFKADVK-----NQVLERLAEQIATLCATLKEYPAVRYRGEYKDNAVLAQMLQDKLDGYKADDPTLGEGPDKA----------------RSQLLILDRGFDPVSPLLHELTFQAMAYDLLPIE-NDVYMYETSGMGDTRMKEVLLDEDDDLWMTLRHKHIAEVSTAVTKSLKDFSASKKMNTGEKTTM 324
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Zebrafish
Match: stxbp1b (syntaxin binding protein 1b [Source:ZFIN;Acc:ZDB-GENE-060531-166]) HSP 1 Score: 83.9593 bits (206), Expect = 2.045e-16 Identity = 77/323 (23.84%), Postives = 143/323 (44.27%), Query Frame = 2
Query: 128 WKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLC---KDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI--PSQTKKTNSYE-LWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSM 1078
WKVL+ DK + ++S+ + G+TI +I +REP+P + AI+ + P+ E++ L +D N IY ++ F I + L L + S S+ +++I + F+ E +F + YS K + ++ + + + ++C T+ P +R V ++ + D + +L G + R L+ILDR D +P+ H T+QA+ +D+L I+ N V + S T E L E+D+ W RHK + E++ + + L+ + +K K++M
Sbjct: 28 WKVLVVDKLSMRMVSSCCKMTDIMSEGITIVEDITKKREPLPTMEAIFLITPSDESVEGLINDFRDPRNPIYRGAHVFFTDAIP-DSLFNLLSKSRASKSIKTLTEI---HIAFLPYESQVFSVDKSDAFQDFYSPFKADVK-----NQVLERLAEQIATLCATLKEYPAVRYRGEYKDNAVLAQMLQDKLDGYKADDPTLGEGPDKA----------------RSQLLILDRGFDPVSPLLHELTFQAMAYDLLPIE-NDVYMYETSGMGDTRMKEVLLDEDDDLWMTLRHKHIAEVSTAVTKSLKDFSASKKMNTGEKTTM 324
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Xenopus
Match: il17b (interleukin 17B [Source:Xenbase;Acc:XB-GENE-491911]) HSP 1 Score: 525.398 bits (1352), Expect = 2.552e-179 Identity = 299/658 (45.44%), Postives = 442/658 (67.17%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI---------PS--QTKKTN--SYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
MA ++R ++ ALK MLNFN P+ K + +WKVLI D+ G DIIS L + K LRD+GVT+ L ++S+R+ IPDVPA+YFV+PT EN++++C+D+ +YESYY+NFIS I+R KLE +A + +++V+ +SK+FDQY NFI LEDD+F+L + +SY +LN + +D E++ ++++IVD LF VT+G +P+IRC GNAAEMVA +LDKKL++NLRD+RNSLF+G + SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ PS + KK N SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LK+ MGL G+ + I+D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEKL ++ L +KSLLD++S PD GT DK+RL L+ + S+ +P ++ +L+Q + + ++ + ++ ++ + +S + KS GL ++ ++ + MEGVKN V K+ LP T+IL +LME S+ ETD+++YFDPK+ R D ++PR K+ FQ+AIVFV+GGGNY+EYQNL++Y K + K I YGCTEL N QF+ QLS LG+
Sbjct: 1 MAASIREKQTVALKRMLNFNVPLVKSSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGVTLHLLLHSDRDAIPDVPAVYFVMPTEENVDRICQDLRTQLYESYYLNFISAISRSKLEDIASAALTANTVSHVSKVFDQYLNFITLEDDMFLLCNQNKDLVSYRALNRSDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCARGNAAEMVAVKLDKKLRENLRDARNSLFTGDNLGA---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEEAPAVESSPSGARPKKKNKKSYDLTVA-DKFWQKHKGSPFPEVAESVQQELESYRTQEDEVKRLKTIMGLEGEDEGAISMISDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKTRKLDVYFEYEEKLMSKSNL-DKSLLDIISDPDAGTPEDKMRLFLIYYITSAQAP-------SEVDLEQYRKALEDAGCSLAPLNYIKQWKAFAKMASAPASYGIG-AAKSKGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDSLMEVKSNPETDDYRYFDPKMLRGNDS-SVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYIKTKQG-------KHILYGCTELFNATQFVKQLSQLGQ 631
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Xenopus
Match: il17b (interleukin 17B [Source:Xenbase;Acc:XB-GENE-491911]) HSP 1 Score: 474.552 bits (1220), Expect = 1.202e-159 Identity = 287/649 (44.22%), Postives = 419/649 (64.56%), Query Frame = 2
Query: 59 IDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI---------PS--QTKKTN--SYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGD-----SDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKL----PFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQ-DAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQL 1933
I ALK MLNFN P+ K + +WKVLI D+ G DIIS L + K LRD+GVT+ L ++S+R+ IPDVPA+YFV+PT EN++++C+D+ +YESYY+NFIS I+R KLE +A + +++V+ +SK+FDQY NFI LEDD+F+L + +SY +LN + +D E++ ++++IVD LF VT+G +P+IRC GNAAEMVA +LDKKL++NLRD+RNSLF+G + SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ PS + KK N SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LK+ MGL G+ S I+D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEKL ++ L +KSLLD++S PD GT DK+RL L+ + S+ +P ++ +L+Q + + ++ + ++ ++ + +S + KS GL ++ ++ + MEGVKN V K+ L P I + Q ETD+++YFDPK+ R D R SF AIVFV+GGGNY+EYQNL++Y K + K I YGCTEL N QF+ Q+
Sbjct: 2 IVALKRMLNFNVPLVKSSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGVTLHLLLHSDRDAIPDVPAVYFVMPTEENVDRICQDLRTQLYESYYLNFISAISRSKLEDIASAALTANTVSHVSKVFDQYLNFITLEDDMFLLCNQNKDLVSYRALNRSDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCARGNAAEMVAVKLDKKLRENLRDARNSLFTGDNLGA---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEEAPAVESSPSGARPKKKNKKSYDLTVA-DKFWQKHKGSPFPEVAESVQQELESYRTQEDEVKRLKTIMGLEGEDEGAISMISDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKTRKLDVYFEYEEKLMSKSNL-DKSLLDIISDPDAGTPEDKMRLFLIYYITSAQAP-------SEVDLEQYRKALEDAGCSLAPLNYIKQWKAFAKMASAPASYGIG-AAKSKGLLSRVMNTGSQFVMEGVKNLVLKQLVLFSIFPVCVICSLTVPQ----ETDDYRYFDPKMLRGND-----RFLISFSLQAIVFVVGGGNYIEYQNLVDYIKTKQG-------KHILYGCTELFNATQFVKQV 615
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Xenopus
Match: il17b (interleukin 17B [Source:Xenbase;Acc:XB-GENE-491911]) HSP 1 Score: 474.552 bits (1220), Expect = 2.083e-159 Identity = 286/647 (44.20%), Postives = 418/647 (64.61%), Query Frame = 2
Query: 65 ALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI---------PS--QTKKTN--SYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGD-----SDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKL----PFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQ-DAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQL 1933
ALK MLNFN P+ K + +WKVLI D+ G DIIS L + K LRD+GVT+ L ++S+R+ IPDVPA+YFV+PT EN++++C+D+ +YESYY+NFIS I+R KLE +A + +++V+ +SK+FDQY NFI LEDD+F+L + +SY +LN + +D E++ ++++IVD LF VT+G +P+IRC GNAAEMVA +LDKKL++NLRD+RNSLF+G + SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ PS + KK N SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LK+ MGL G+ S I+D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEKL ++ L +KSLLD++S PD GT DK+RL L+ + S+ +P ++ +L+Q + + ++ + ++ ++ + +S + KS GL ++ ++ + MEGVKN V K+ L P I + Q ETD+++YFDPK+ R D R SF AIVFV+GGGNY+EYQNL++Y K + K I YGCTEL N QF+ Q+
Sbjct: 18 ALKRMLNFNVPLVKSSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGVTLHLLLHSDRDAIPDVPAVYFVMPTEENVDRICQDLRTQLYESYYLNFISAISRSKLEDIASAALTANTVSHVSKVFDQYLNFITLEDDMFLLCNQNKDLVSYRALNRSDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCARGNAAEMVAVKLDKKLRENLRDARNSLFTGDNLGA---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEEAPAVESSPSGARPKKKNKKSYDLTVA-DKFWQKHKGSPFPEVAESVQQELESYRTQEDEVKRLKTIMGLEGEDEGAISMISDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKTRKLDVYFEYEEKLMSKSNL-DKSLLDIISDPDAGTPEDKMRLFLIYYITSAQAP-------SEVDLEQYRKALEDAGCSLAPLNYIKQWKAFAKMASAPASYGIG-AAKSKGLLSRVMNTGSQFVMEGVKNLVLKQLVLFSIFPVCVICSLTVPQ----ETDDYRYFDPKMLRGND-----RFLISFSLQAIVFVVGGGNYIEYQNLVDYIKTKQG-------KHILYGCTELFNATQFVKQV 629
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Xenopus
Match: il17b (interleukin 17B [Source:Xenbase;Acc:XB-GENE-491911]) HSP 1 Score: 467.618 bits (1202), Expect = 6.999e-157 Identity = 282/640 (44.06%), Postives = 413/640 (64.53%), Query Frame = 2
Query: 77 MLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI---------PS--QTKKTN--SYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGD-----SDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKL----PFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQ-DAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFL 1924
MLNFN P+ K + +WKVLI D+ G DIIS L + K LRD+GVT+ L ++S+R+ IPDVPA+YFV+PT EN++++C+D+ +YESYY+NFIS I+R KLE +A + +++V+ +SK+FDQY NFI LEDD+F+L + +SY +LN + +D E++ ++++IVD LF VT+G +P+IRC GNAAEMVA +LDKKL++NLRD+RNSLF+G + SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ PS + KK N SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LK+ MGL G+ S I+D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEKL ++ L +KSLLD++S PD GT DK+RL L+ + S+ +P ++ +L+Q + + ++ + ++ ++ + +S + KS GL ++ ++ + MEGVKN V K+ L P I + Q ETD+++YFDPK+ R D R SF AIVFV+GGGNY+EYQNL++Y K + K I YGCTEL N QF+
Sbjct: 1 MLNFNVPLVKSSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGVTLHLLLHSDRDAIPDVPAVYFVMPTEENVDRICQDLRTQLYESYYLNFISAISRSKLEDIASAALTANTVSHVSKVFDQYLNFITLEDDMFLLCNQNKDLVSYRALNRSDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCARGNAAEMVAVKLDKKLRENLRDARNSLFTGDNLGA---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEEAPAVESSPSGARPKKKNKKSYDLTVA-DKFWQKHKGSPFPEVAESVQQELESYRTQEDEVKRLKTIMGLEGEDEGAISMISDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKTRKLDVYFEYEEKLMSKSNL-DKSLLDIISDPDAGTPEDKMRLFLIYYITSAQAP-------SEVDLEQYRKALEDAGCSLAPLNYIKQWKAFAKMASAPASYGIG-AAKSKGLLSRVMNTGSQFVMEGVKNLVLKQLVLFSIFPVCVICSLTVPQ----ETDDYRYFDPKMLRGND-----RFLISFSLQAIVFVVGGGNYIEYQNLVDYIKTKQG-------KHILYGCTELFNATQFV 605
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Xenopus
Match: il17b (interleukin 17B [Source:Xenbase;Acc:XB-GENE-491911]) HSP 1 Score: 418.313 bits (1074), Expect = 2.349e-138 Identity = 257/595 (43.19%), Postives = 382/595 (64.20%), Query Frame = 2
Query: 221 LNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI---------PS--QTKKTN--SYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGD-----SDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKL----PFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQ-DAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQL 1933
L ++S+R+ IPDVPA+YFV+PT EN++++C+D+ +YESYY+NFIS I+R KLE +A + +++V+ +SK+FDQY NFI LEDD+F+L + +SY +LN + +D E++ ++++IVD LF VT+G +P+IRC GNAAEMVA +LDKKL++NLRD+RNSLF+G + SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ PS + KK N SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LK+ MGL G+ S I+D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEKL ++ L +KSLLD++S PD GT DK+RL L+ + S+ +P ++ +L+Q + + ++ + ++ ++ + +S + KS GL ++ ++ + MEGVKN V K+ L P I + Q ETD+++YFDPK+ R D R SF AIVFV+GGGNY+EYQNL++Y K + K I YGCTEL N QF+ Q+
Sbjct: 5 LLLHSDRDAIPDVPAVYFVMPTEENVDRICQDLRTQLYESYYLNFISAISRSKLEDIASAALTANTVSHVSKVFDQYLNFITLEDDMFLLCNQNKDLVSYRALNRSDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCARGNAAEMVAVKLDKKLRENLRDARNSLFTGDNLGA---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEEAPAVESSPSGARPKKKNKKSYDLTVA-DKFWQKHKGSPFPEVAESVQQELESYRTQEDEVKRLKTIMGLEGEDEGAISMISDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKTRKLDVYFEYEEKLMSKSNL-DKSLLDIISDPDAGTPEDKMRLFLIYYITSAQAP-------SEVDLEQYRKALEDAGCSLAPLNYIKQWKAFAKMASAPASYGIG-AAKSKGLLSRVMNTGSQFVMEGVKNLVLKQLVLFSIFPVCVICSLTVPQ----ETDDYRYFDPKMLRGND-----RFLISFSLQAIVFVVGGGNYIEYQNLVDYIKTKQG-------KHILYGCTELFNATQFVKQV 564
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Mouse
Match: Scfd1 (Sec1 family domain containing 1 [Source:MGI Symbol;Acc:MGI:1924233]) HSP 1 Score: 520.005 bits (1338), Expect = 2.918e-177 Identity = 299/658 (45.44%), Postives = 438/658 (66.57%), Query Frame = 2
Query: 41 NLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQT-------------KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSH---QTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
++R R+ ALK MLNFN P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PIPDVPA+YFV+PT ENI++LC+D+ N +YESYY+NFIS I+R KLE +A + + +V Q++K+FDQY NFI LEDD+FVL + +SY ++N +D E++ ++++IVD LF VT+G +P+IRC G AAEMVA +LDKKL++NLRD+RNSLF+G + T SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ T K SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEK+ ++ L +KSLLD++S PD GT DK+RL L+ + + +P ++ +L+Q + + ++S + ++ ++ ++S S+ TK GL ++ ++ + MEGVKN V K+ LP T+IL NLME S+ ETD+++YFDPK+ RS D ++PR KS FQ+AIVFV+GGGNY+EYQNL++Y K + + K I YGC+E+ N QF+ QLS LG+
Sbjct: 11 SIRERQTVALKRMLNFNVPHVKNSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDPLGT---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPAGARPKRKNKKSYDL-TPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTL-DKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAP-------SEVDLEQYKKALTDAGCNLSPLQYIKQWKAF----AKMASTPASYGNTTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRSNDS-SVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIK-------AKQGKHILYGCSEIFNATQFIKQLSQLGQ 638
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Mouse
Match: Scfd1 (Sec1 family domain containing 1 [Source:MGI Symbol;Acc:MGI:1924233]) HSP 1 Score: 339.732 bits (870), Expect = 1.584e-110 Identity = 183/385 (47.53%), Postives = 263/385 (68.31%), Query Frame = 2
Query: 41 NLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQT-------------KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSS 1141
++R R+ ALK MLNFN P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PIPDVPA+YFV+PT ENI++LC+D+ N +YESYY+NFIS I+R KLE +A + + +V Q++K+FDQY NFI LEDD+FVL + +SY ++N +D E++ ++++IVD LF VT+G +P+IRC G AAEMVA +LDKKL++NLRD+RNSLF+G + T SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ T K SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LKS MGL G+ + ++D+T KL+ VS+
Sbjct: 11 SIRERQTVALKRMLNFNVPHVKNSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDPLGT---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPAGARPKRKNKKSYDL-TPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSA 385
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Mouse
Match: Vps45 (vacuolar protein sorting 45 [Source:MGI Symbol;Acc:MGI:891965]) HSP 1 Score: 105.916 bits (263), Expect = 1.911e-23 Identity = 150/615 (24.39%), Postives = 264/615 (42.93%), Query Frame = 2
Query: 131 KVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSE-REPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFER----PLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVN---IPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLE-VIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLD---MLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQV--SDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTK---KISYGCTELLNGEQFL 1924
KVL+ DK I+S ++TQ + V + I+S+ RE + + AI F+ PT EN+ L +++ Y Y+I F + I++ ++ LA ++D ++++ + Y ++I + LF L+ + G + A ++ GL ++ +++ P+IR + A LG + S F R PLL+ILDR D TP+ + WTYQA+VH++L I N ++ +P +K L ENDEF+ + + EI I+ +E K + KE +L+S + + K+S TVS H + L+ + ER L E+E++L A Q H +L + +L +P T D +RL++L L+ +NS+ + +D + ++ +++AV R+ +L S + + + +F+ ++GV+N V +H+ PF LH ++ + ++ + + Y P R QD IVF+IGG Y E + Y +RT +I G T + N + FL
Sbjct: 23 KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVEYLIQELRRPKYSIYFIYFSNVISKSDVKSLA----EADEQEVVAEVQEFYGDYIAVNPHLFSLN-----------ILGCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAA----------------------KRLG-ECVKQVISKEYELFEFRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKRPKEQQKLESIADMKAFVENYPQFKKMSGTVSK-------------HVTVVGELSRLVSERNLLEVSEVEQEL-ACQNDHSSALQNVKRLLQNPKVTEFDAVRLVMLYALHYERHSSNSLPGLI---VDLRSKGV--AEKYRKLVSAVVEYGGKRVRGSDLFSPK-----DAVAITKQFLKG-----LKGVEN-VYTQHQ-PF---LHETLDHLIKGRLKENLYPYLGPSTLRDRP-----------QDIIVFIIGGATYEE----------ALTVYNLNRTTPGVRIVLGGTTIHNTKSFL 544
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Mouse
Match: Scfd1 (Sec1 family domain containing 1 [Source:MGI Symbol;Acc:MGI:1924233]) HSP 1 Score: 86.6557 bits (213), Expect = 1.901e-19 Identity = 59/168 (35.12%), Postives = 98/168 (58.33%), Query Frame = 2
Query: 1244 ELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSH---QTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSAD 1735
E EEK+ ++ L +KSLLD++S PD GT DK+RL L+ + + +P+ + +L+Q + + ++S + ++ ++ ++S S+ TK GL ++ ++ + MEGVKN V K+ LP T+IL NLME S+ ETD+++YFDPK+ RS D
Sbjct: 2 EYEEKIMSKTTL-DKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAPS-------EVDLEQYKKALTDAGCNLSPLQYIKQWKAF----AKMASTPASYGNTTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRSND 157
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Mouse
Match: Stxbp2 (syntaxin binding protein 2 [Source:MGI Symbol;Acc:MGI:107370]) HSP 1 Score: 93.5893 bits (231), Expect = 2.112e-19 Identity = 85/325 (26.15%), Postives = 148/325 (45.54%), Query Frame = 2
Query: 92 SPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNG---IYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCP--PGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYE---LWCENDEFWRDERHKPLPEIADVIQQGLEVIKS 1042
S + + V D WKVLI D + I+S+ + G+TI +IN REPIP + AIY + PT +++ L D Y++ +I F +L S + +V + +I + F+ E +F L + Y AG+ +++DA+ I ++C T+ P IR P + A++ +++ + L S G + R L+I+DR+ D +P+ H T+QA+ +D+L+I+ +T + T + S E L E+D+ W + RH IADV ++ E++K+
Sbjct: 16 SGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINKRREPIPSLEAIYLLSPTEKSVQALIADFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSRL-AKAVKTLKEI---HLAFLPYEAQVFSLDAPHSTYNLYCPFR-AGERGRQLDALAQQIA----TLCATLQEYPSIRYRKGPEDTAQLA----------------HAVLAKLNAFKADTPSLGEGPEKT--RSQLLIMDRAADPVSPLLHELTFQAMAYDLLDIEQDTYRYET-TGLSESREKAVLLDEDDDLWVELRHM---HIADVSKKVTELLKT 309
BLAST of sec1 family domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q8BRF7|SCFD1_MOUSE (Sec1 family domain-containing protein 1 OS=Mus musculus OX=10090 GN=Scfd1 PE=1 SV=1) HSP 1 Score: 520.005 bits (1338), Expect = 2.041e-176 Identity = 299/658 (45.44%), Postives = 438/658 (66.57%), Query Frame = 2
Query: 41 NLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQT-------------KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSH---QTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
++R R+ ALK MLNFN P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PIPDVPA+YFV+PT ENI++LC+D+ N +YESYY+NFIS I+R KLE +A + + +V Q++K+FDQY NFI LEDD+FVL + +SY ++N +D E++ ++++IVD LF VT+G +P+IRC G AAEMVA +LDKKL++NLRD+RNSLF+G + T SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ T K SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEK+ ++ L +KSLLD++S PD GT DK+RL L+ + + +P ++ +L+Q + + ++S + ++ ++ ++S S+ TK GL ++ ++ + MEGVKN V K+ LP T+IL NLME S+ ETD+++YFDPK+ RS D ++PR KS FQ+AIVFV+GGGNY+EYQNL++Y K + + K I YGC+E+ N QF+ QLS LG+
Sbjct: 11 SIRERQTVALKRMLNFNVPHVKNSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDPLGT---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPAGARPKRKNKKSYDL-TPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTL-DKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAP-------SEVDLEQYKKALTDAGCNLSPLQYIKQWKAF----AKMASTPASYGNTTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRSNDS-SVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIK-------AKQGKHILYGCSEIFNATQFIKQLSQLGQ 638
BLAST of sec1 family domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q62991|SCFD1_RAT (Sec1 family domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Scfd1 PE=1 SV=1) HSP 1 Score: 518.079 bits (1333), Expect = 1.345e-175 Identity = 299/661 (45.23%), Postives = 439/661 (66.41%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQT-------------KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSH---QTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
MA ++R R+ ALK MLNFN P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PI DVPA+YFV+PT ENI++LC+D+ N +YESYY+NFIS I+R KLE +A + +++V Q++K+FDQY NFI LE+D+FVL + +SY ++N +D E++ ++++IVD LF VT+G +P+IRC G AAEMVA +LDKKL++NLRD+RNSLF+G + T SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ T K SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEK+ ++ L +KSLLD++S PD GT DK+RL L+ + + +P ++ +L+Q + + ++S + ++ ++ ++S S+ TK GL ++ ++ + MEGVKN V K+ LP T+IL NLME S+ ETD+++YFDPK+ RS D ++PR KS FQ+AIVFV+GGGNY+EYQNL++Y K + K I YGC+E+ N QF+ QLS LG+
Sbjct: 6 MAASIRERQTVALKRMLNFNVPHVKNSPGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIRDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAANAVTQVAKVFDQYLNFITLEEDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDPLGT---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPTGARPKRKNKKSYDL-TPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTL-DKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAP-------SEVDLEQYKKALTDAGCNLSPLQYIKQWKAF----AKMASTPASYGNTTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRSNDS-SVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIKGKQG-------KHILYGCSEIFNATQFIKQLSQLGQ 636
BLAST of sec1 family domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q8WVM8|SCFD1_HUMAN (Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4) HSP 1 Score: 514.227 bits (1323), Expect = 4.490e-174 Identity = 294/655 (44.89%), Postives = 434/655 (66.26%), Query Frame = 2
Query: 41 NLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQT-------------KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
++R R+ ALK MLNFN P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PIPDVPA+YFV+PT ENI+++C+D+ N +YESYY+NFIS I+R KLE +A + + +V Q++K+FDQY NFI LEDD+FVL + +SY ++N +D E++ ++++IVD LF VT+G +P+IRC G AAEMVA +LDKKL++NLRD+RNSLF+G + SF+RPLLV++DR++DLATP++H WTYQALVHD+L+ N VN+ + K SY+L D+FW+ + P PE+A+ +QQ LE +++E E+ +LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + + IK RKLD+YFE EEK+ ++ L +KSLLD++S PD GT DK+RL L+ + + +P+ + +L+Q + + +++ + ++ ++ + +S S TK GL ++ ++ + MEGVKN V K+ LP T+IL NLME S+ ETD+++YFDPK+ R D ++PR K+ FQ+AIVFV+GGGNY+EYQNL++Y K + K I YGC+EL N QF+ QLS LG+
Sbjct: 14 SIRERQTVALKRMLNFNVPHIKNSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDTLGA---------GQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDL-TPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTL-DKSLLDIISDPDAGTPEDKMRLFLIYYISTQQAPSEA-------DLEQYKKALTDAGCNLNPLQYIKQWKAFTKMASAPASYG-STTTKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPETDDYRYFDPKMLRGNDS-SVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYIKGKQG-------KHILYGCSELFNATQFIKQLSQLGQ 641
BLAST of sec1 family domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q24179|SLY1_DROME (Protein sly1 homolog OS=Drosophila melanogaster OX=7227 GN=Slh PE=2 SV=4) HSP 1 Score: 484.952 bits (1247), Expect = 1.057e-162 Identity = 271/652 (41.56%), Postives = 428/652 (65.64%), Query Frame = 2
Query: 38 LNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSH---LSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQT------KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDIT-----DSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRS--HRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLG 1945
L LR R+I+A+K MLN NS K + + +WK+LI D+ G DIIS + + K LR+LGVT+ + ++S+R+ IPDVPAIYF LPT EN++++ +D +G+Y+ Y++NF++PI R K+E LA + + V I +++DQY NFI LEDD F+L ++ +SY ++N A D+E++A+++SIVD LF++ VT+G +P+IRCP +AAEMVA++L+KKL++NL D+R +LF H TQ+ SF+RP+L++LDR++DLATP++H W+YQALVHD+L++ N V + +T KK + +L ND FW + P P +A+ IQ+ LE ++ E+E+ +LK+SMG+ G+SDI D+T +L++ V+SL +EKK+L+++HT IAT + + IK R+LD +FE+EEK+ ++Q L L + G A DKLRL ++ + + P + E ++L + ++ D++ +A V+ + +R S + +++ TK+ +FTK +S ++ MEGVKN V K+H LP TKI +ME S+ ETD++ Y DPKL + G+ LP+ ++ FQDA+VF++GGGNY+EYQNL+++ K ++ S+ ++I YG + L N QFL +LS LG
Sbjct: 2 LTLRERQINAIKQMLNLNSQQPKALAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRNSAAEMVARKLEKKLRENLWDARANLF----------HMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLVYVEDETASAGARKKPKACDL-DRNDRFWMTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAILNFIKARRLDSFFEIEEKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQQLP--------ESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGGGTKTVSMFTKLVSQGSSFVMEGVKNLVVKRHNLPVTKITEQVMECRSNAETDDYLYLDPKLLKG--GEVLPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQT---SNVQRRIIYGASTLTNARQFLKELSALG 629
BLAST of sec1 family domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|O18637|SLY1_DROVI (Protein sly1 homolog OS=Drosophila virilis OX=7244 GN=Slh PE=3 SV=1) HSP 1 Score: 478.789 bits (1231), Expect = 4.508e-160 Identity = 276/671 (41.13%), Postives = 431/671 (64.23%), Query Frame = 2
Query: 38 LNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSH---LSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQ--TKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDIT-----DSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRS--HRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKH----------------------KLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLG 1945
L LR R+I+A+K MLN NS K + D +WK+LI D+ G DIIS + + K LR+LGVT+ + ++S+R+ IPDVPA+YF LPT EN++++ +D NG+Y+ Y++NF++PI R K+E LA + + V I +++DQY NFI LEDD F+L ++ +SY ++N A D+E++A+++SIVD LF++ VT+G +P+IRCP +AAEMVA++L+KKL++NL D+R +LF H TQ+ SF+RP+L++LDR++DLATP++H W+YQALVHD+L++ N V + + KK + +L ND FW + P P +A+ IQ+ LE ++ E+E+ +LK+SMG+ G+SDI D+T L+ V+SL +EKK+L+++HT IAT + + IK R+LD YFE+EEK+ ++Q L +K LL++L + G DKLRL ++ + + P + EL++L + S+ D++ +A V+ +S +R S + +++ T++ +FTK +S ++ MEGVKN V K+H LP TKI +ME S+ ETD++ Y PKL + GD LP+ ++ FQDA+VF++GGGNY+EYQNL+++ K ++ S+ ++I YG + L N QFL +LS LG
Sbjct: 2 LTLRERQINAIKQMLNLNSQQPKAMAADAVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAVYFCLPTDENLDRIQQDFSNGLYDIYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRNSAAEMVARKLEKKLRENLWDARANLF----------HMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLVYVEDEGARKKPKACDL-DRNDRFWVTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTAMLTSAVNSLPQLMEKKRLIDMHTKIATAILNCIKARRLDSYFEIEEKIMSKQTL-DKPLLELLRDAEFGQPEDKLRLYIIYYICAQQLP--------EPELERLREALQSAGCDLTALAYVQRWKSIMNRSPSISQATQYEGGGTRTVSMFTKLVSQGSSFVMEGVKNLVVKRHVNINLRLGSDRVKAKLIPNFLENLPVTKITEQVMECRSNAETDDYLYLAPKLLKG--GDVLPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQT---SNVHRRIIYGGSTLTNARQFLKELSALG 647
BLAST of sec1 family domain-containing protein 1 vs. TrEMBL
Match: A0A1S3IDJ0 (sec1 family domain-containing protein 1 OS=Lingula unguis OX=7574 GN=LOC106163317 PE=3 SV=1) HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0 Identity = 318/657 (48.40%), Postives = 450/657 (68.49%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI--------PSQT----KKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
MA ++R ++ AL+ MLNFN PI+K + + WKVLI D+ G DIIS L T K LRDLGVT+ L ++S+REPIPDVPAIYFV+PT EN+ ++C+D+ + +YESYY NFIS I+R++LE +A S Q+ +V Q+SK+FDQY NFI LEDD+F+L + +SY ++N D E++A +++IVD LFSV VT+GT+P+IRCP GNAAEMV+++LDKKL++N+RD+RNSLF+ M + SF+RPLLV+LDR++DLATP +H WTYQAL HD+L++K N V I P+ + KK SY+L D+FW +++ P P +A+ +Q+ LE +S+E E+ +LK MGL G+ D ++D+T KL+ VSSL LEKK+L+++H NIAT L DQIK RKLD YFE+EEK+ ++ L EKSL+D+++ P+ GT DKLRL ++AL+ +TD E+DQ + ++ +I + +R R++ + S+ T + G+F+K +S + + MEGVKN V KKHKLP T+I LME S ETD+++YFDPK+ R+ D ++PR KS FQ+A VF++GGGNY+EYQNL++Y +K QS KKI+YGCTELLN QFL QL+ LG+
Sbjct: 1 MAASMREKQTAALQRMLNFNMPISKASSSEPQWKVLIYDRFGQDIISPLLTVKELRDLGVTLHLLLHSDREPIPDVPAIYFVMPTEENVQRICRDLQSQMYESYYFNFISAISRQRLEDIATSAIQTHAVTQVSKVFDQYLNFISLEDDMFILRYQNSEPISYYAINRGDVKDSEMEATMDTIVDSLFSVFVTLGTVPIIRCPRGNAAEMVSEKLDKKLRENVRDARNSLFTADSMQS---------GQFSFQRPLLVLLDRNMDLATPFHHTWTYQALAHDVLDLKLNRVEIEEAVEQKSPAHSARPKKKKKSYDL-NTTDQFWHEQKGSPFPTVAEAVQEALESYRSQEDEVKRLKHVMGLEGEDDAAISMLSDTTAKLTSAVSSLPELLEKKRLIDMHMNIATALLDQIKARKLDTYFEIEEKMMSKASL-EKSLMDIITDPEAGTPEDKLRLFIIALVCGPT--------MTDAEVDQYAVALQGANCEIDSLKYIRRWRAYAKMTAA-PSQYGGGGTTTVGMFSKLMSQASNFAMEGVKNLVVKKHKLPVTRIADALMEMKSYQETDDYRYFDPKMLRATDS-SVPRNKSPFQEAYVFIVGGGNYIEYQNLVDY---YKGKTQSSPGKKITYGCTELLNSSQFLRQLAALGK 633
BLAST of sec1 family domain-containing protein 1 vs. TrEMBL
Match: A0A210QZK8 (Sec1 family domain-containing protein 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT18937 PE=3 SV=1) HSP 1 Score: 551.592 bits (1420), Expect = 0.000e+0 Identity = 309/655 (47.18%), Postives = 446/655 (68.09%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIP----------SQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGD-----SDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
MA +LR ++I ALK M+NFN P TK + + WKVL+ D+ G DIIS L + K LRD+GVT+ LN++S+R+PIPDVPAIYFVLPT +NI +LC+D N +YESY++NFIS + R+KLE +A + Q + V+Q+SKI+DQY NFI LEDD+FVL + + S+SY ++N D +++ I++++VD LF V VT+G +PVIRCP GNAAEMVA++LDKKL++NLRD+RNS F+ + T SF+RPLLV+LDR+LDLAT ++H WTYQAL HD+ N++ N V + + KK SY+L D FW+ ++ P P +A+ +Q+ L+ +++E E+ +LK+ MGL G+ S ++D+T KL+ TVS+L LEKK+L+++HTNIAT + QIK RKLD YFE EEKL ++ L +KSL+DM+S PD GT DK+RL ++AL+ G P +++ E+DQ C + ++ DIS + +R +++ + S+ V TK+ G+F+K ++ +FMEGVKN V KKH LP T+I+ LME S + ++F+YFDPKL R AD ++PR KS FQ+A VFV+GGGNY+EYQNL++Y K S +++ YGC+++ + QFL QL LG+
Sbjct: 1 MASSLREKQIQALKRMINFNQPPTKATSSEPQWKVLVYDRFGQDIISPLMSVKELRDMGVTLHLNLHSDRDPIPDVPAIYFVLPTDDNIQRLCRDFGNQLYESYFLNFISAVPRQKLEDIASAAIQQNCVHQVSKIYDQYLNFISLEDDMFVLRNQERESISYYAINRGDVKDTDMEFIMDTVVDSLFCVFVTLGVVPVIRCPKGNAAEMVAEKLDKKLRENLRDARNSFFTSDSIQT---------GQFSFQRPLLVLLDRNLDLATMLHHTWTYQALTHDVFNLQLNRVEVEETVEAKSPGGAMLKKKKSYDL-NPTDRFWQAQKGSPFPMVAEAVQEELDSYRAQEDEVKKLKAVMGLEGEDESAISQLSDTTAKLTSTVSNLPELLEKKRLIDMHTNIATAVLGQIKARKLDAYFETEEKLMSKAVL-DKSLMDMISDPDSGTPEDKVRLFVIALI--CGPP------MSEAEIDQYCVALQGANCDISPITYIRRWKAYTKMTAA-PSQYVGGGTKTVGMFSKLMTTGSQFFMEGVKNLVIKKHNLPATRIIDALMEMKSLQDVEDFRYFDPKLLR-ADASSVPRNKSPFQEAYVFVVGGGNYIEYQNLMDYVKTKSG---SAGQRRVVYGCSDISSASQFLKQLGHLGQ 631
BLAST of sec1 family domain-containing protein 1 vs. TrEMBL
Match: R7U537 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_149404 PE=3 SV=1) HSP 1 Score: 550.051 bits (1416), Expect = 0.000e+0 Identity = 308/648 (47.53%), Postives = 437/648 (67.44%), Query Frame = 2
Query: 77 MLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLH------DDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI------------PSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQ-NLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLG 1945
MLNFN P+TK + WKVL+ D G DIIS L + + LR+LGVT+ L ++S+REPI DVPA+YFV PT +N+ ++CKD + +YESYY+NFIS I+R+KLE LA + Q++SV Q++KIFDQY NFI LEDD+F L D S+SY S+N D EI+ ++++IV+ LF V VT+G +P+IRCP NAAEMVA++LDKKL+DN+RD+RNSLF+G + + SF+RPLLVILDR++DLATP +H WTYQAL HD+L +K N V I P + KK SY+L D FW + + P P +A+ +Q+ L+ K++E E+ +LK++MGL G+ D ++D+T +L+ VSSL LE K+L+++HTN+AT L +QIK R LD+YFE EE+L +R L +KS+LD++ P+ GT DK+RL ++ L+ G P ++D E+DQ CS + + ++S A++++R + +S+ +SS TK+ G+F+K +S + + MEGVKN V KKH LP TK+L +LM+ S ETD+F+YFDPKL R+ D +++PR +S FQ+A+VFV+GGGNY+EYQNL+EY K + K++ YGCTELLN QFL QL LG
Sbjct: 1 MLNFNIPLTKTSLSEPQWKVLVYDHWGQDIISPLLSVRELRELGVTLHLLLDSDREPIQDVPAVYFVRPTDDNVKRICKDFHSQLYESYYMNFISAISRQKLEDLALAAIQTNSVTQVTKIFDQYLNFISLEDDMFCLRHHSDVADSSKESISYYSINRGDVKDTEIERMMDNIVESLFCVFVTLGQVPIIRCPRNNAAEMVAEKLDKKLRDNIRDTRNSLFAGENVQS---------GQFSFQRPLLVILDRNIDLATPFHHTWTYQALSHDVLQLKLNRVEIEEKVQVNAPGRAPVEKKKVRSYDL-NPTDGFWEEHKGSPFPTVAEAVQEKLDAYKAQEDEVKRLKTAMGLEGEDDETISMVSDNTARLTSAVSSLPELLEMKRLIDMHTNVATALLEQIKARMLDLYFETEERLMSRTTL-DKSILDIIRDPEAGTVEDKVRLFIINLI--CGPP------VSDAEIDQYCSVLQDAGCNLS---AIQYIRRWKTYSKLPMSSAYSGGGTKTVGMFSKLVSTASQFAMEGVKNLVVKKHNLPVTKVLDSLMDMKSSSETDDFRYFDPKLLRATDSNSIPRNRSPFQEAMVFVVGGGNYIEYQNLVEYCKGKAGGANA---KRVIYGCTELLNASQFLKQLEKLG 623
BLAST of sec1 family domain-containing protein 1 vs. TrEMBL
Match: A0A2C9K4M4 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106051062 PE=3 SV=1) HSP 1 Score: 546.199 bits (1406), Expect = 0.000e+0 Identity = 313/661 (47.35%), Postives = 450/661 (68.08%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNT------------VNIPSQTKKTNS--YELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHS--QNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
MA++L+ ++I+ALK MLNFN PITK N + WKVLI D+ G DIIS L T K LRD+GVT+ L+++S+R+PIPDVPAIYFV+PT +NI +LC+D N +YESYY+NFIS I+R+KLE +A + Q+++V Q+ K+FDQY NFI LE++LF L S+SY ++N D E+D I+ SIVD LFSV VT+G +P+IRCP GNAAEMVA++LDKKL++NLRD+RNSLF+ S G SF+RPLLVILDR+LD+AT ++H WTYQAL HD+L++K N + P++ +T Y+L D+ W ++ P PE+A+ +Q+ L + +E E+ +LK+++GL G+ D ++D+T +L+ V+SL LEKK+L+++H NIAT L +QIK RKLD YFE EEK+ +R L+ KSL+D++S P+ G DK+RL ++AL+ G P +++ E+DQ C + ++ DIS AV++VR + +S Q +S+ S+ +F+ +S + MEGVKN V K H LP T+I+ LM+ S ++++F+YFDPKL R AD ++PR K+ FQ+A VF++GGGNY+E+QNL++Y K+ KST KKI YGC++L+N QFL QLS LG+
Sbjct: 1 MAISLQEKQINALKRMLNFNQPITKATNAEPQWKVLIYDRFGQDIISPLLTIKELRDMGVTLHLSLHSDRDPIPDVPAIYFVMPTEDNIQRLCRDFQNQLYESYYLNFISAISRQKLEDIAQAALQANAVQQVCKVFDQYLNFISLENELFTLRHQDRDSISYYAINKGDVKDTEMDVIMESIVDSLFSVFVTMGVVPIIRCPKGNAAEMVAEKLDKKLRENLRDTRNSLFT----------SDGVPGQFSFQRPLLVILDRNLDMATMLHHTWTYQALAHDVLDLKLNRIEIEEIIEDGSHASSPARKPRTKKKVYDL-SARDKMWMAQKGHPFPEVAEAVQEELNNYRQEEGEVKKLKAALGLEGEDDTAISMLSDNTARLTSAVTSLPELLEKKRLIDMHMNIATALLEQIKARKLDTYFETEEKMMSRASLN-KSLMDIISDPEAGKPEDKVRLFIIALI--CGPP------MSEAEIDQYCVALQGANCDIS---AVQYVRRWKSYSKLQAPASQYTGGGISSTSMFSGLLSKGSQFVMEGVKNLVVKGHNLPATRIVDALMDLKSLPDSEDFRYFDPKLLR-ADATSVPRNKTPFQEAYVFIVGGGNYIEFQNLMDYVKS-KST--PSMPKKIVYGCSDLVNASQFLKQLSHLGQ 634
BLAST of sec1 family domain-containing protein 1 vs. TrEMBL
Match: A0A2T7PKL7 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_05233 PE=3 SV=1) HSP 1 Score: 544.273 bits (1401), Expect = 0.000e+0 Identity = 303/659 (45.98%), Postives = 451/659 (68.44%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI----------PSQTKKT--NSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGD-----SDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQV--SHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
MA +LR +++ ALK MLNFN P TK + WK+L+ D+ G DIIS L T K LRDLGVT+ LN++++R+PIPDVP IYFV+PT +NI ++C+D NG+YESYY+NFIS ++R+KLE +A + QS +V+Q+SK+ DQY NFI LEDDLF L ++SY ++N D E++AI++ IVD LFSV VT+GT+P+IRCP GNAAEMV+++LDKKL+DNLRD+RNSLF+ S SF+RPLLV+LDR+ DLAT ++H WTYQAL HD+L+++ N V I PS+ +T +Y++ + D+FW ++ P P +A+ +Q+ L+ +++E E+ +LK++MGL G+ S ++DST KL+ VSSL LE+K+L+++HTNIAT L +QIK+RKLD YFE EE++ ++ L + SL+D++S P+ G DK+RL ++AL+ G P +++ E+DQ C + +S+ D++ V++VR + +S+ ++ + ++G+FT +S ++ MEGVKN V K+H LP T+I+ LME S + ++++YFDPK+ R AD N+PR KS FQ+A VF++GGGNY+EYQNL++Y ++ + Q KKI YGC++L+ FL QL+ LG+
Sbjct: 1 MASSLREKQVTALKRMLNFNVPFTKATVAEPQWKILVYDRCGQDIISPLLTVKELRDLGVTLHLNLHTDRDPIPDVPVIYFVMPTDDNIQRICRDFQNGLYESYYLNFISAVSRQKLEDIASAAVQSGTVHQVSKVVDQYLNFISLEDDLFTLRHQDREAISYYAINRGDVKDSEMEAIMDVIVDSLFSVFVTMGTVPIIRCPRGNAAEMVSEKLDKKLRDNLRDARNSLFA----------SDAVPGQFSFQRPLLVVLDRNQDLATMLHHTWTYQALAHDVLDLRLNRVEIEEVIDEGIHSPSRKPRTKKKAYDMNTK-DKFWMAQKGSPFPTVAEAVQEELDAYRTEEDEVKKLKAAMGLEGEDVSAISMLSDSTAKLTSAVSSLPELLERKRLIDMHTNIATALLEQIKQRKLDTYFETEERMMSKSTLSQ-SLMDIISDPEAGKPEDKVRLFIIALI--CGPP------MSEAEIDQYCVALQASNCDLT---PVQYVRRWKSYSKITATPSLYTGGSISTTGMFTNLLSKGSSFVMEGVKNLVVKRHNLPATRIVDALMELKSLQDVEDYRYFDPKMLR-ADSANVPRNKSPFQEAYVFMVGGGNYIEYQNLVDYARSKAAVAQ----KKIIYGCSDLVYATMFLKQLAQLGK 631
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Cavefish
Match: scfd1 (sec1 family domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-030116-3]) HSP 1 Score: 459.144 bits (1180), Expect = 1.445e-154 Identity = 267/604 (44.21%), Postives = 402/604 (66.56%), Query Frame = 2
Query: 203 LGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIP-----------SQTKKTN--SYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSS---GLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
+G+T+ L ++S+R+PIPDVPAIYFV+PT ENI+++C+D+ N +YESYY+NFIS I+R KLE +A S +++VNQ++K+FDQY NFI LEDD+FVL + +SY ++N D +++AI+++IVD LF VT+G +P+IRCP GNAAEMVA +LDKKL++NLRD+RNSLF+G M SF+RPL V+ DR+LDLATP++H WTYQAL+HD+L++ N V++ ++ KK N SY+L D+FW+ + P PE+A+ +Q+ L+ +++E+E+ +LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + D IK RKLD+YFE EEKL ++ L +KSLLD+++ PD GT DK+RL L+ + S P ++ +L+Q + + D+S + ++ N + + +T + LF++ ++ + MEGVKN V K+H LP T+IL NLM+ S+ ETD+++YFDPK+ R ++ + P L++ AIVFV+GGGNY+EYQNL++Y K + + K++ YGC+EL + QF QLS LG+
Sbjct: 1 MGITLHLLLHSDRDPIPDVPAIYFVMPTEENIDRICQDLRNQLYESYYLNFISAISRSKLEDIASSALAANAVNQVTKVFDQYLNFITLEDDMFVLCNQNKEQISYHAINKPDIMDTDMEAIMDTIVDSLFCFFVTLGAVPIIRCPRGNAAEMVAVKLDKKLRENLRDARNSLFTGDTMGA---------GQFSFQRPLFVLADRNLDLATPLHHTWTYQALIHDVLDLHLNRVSLEESPGSEVSPAGARPKKKNKKSYDLTAA-DKFWQKHKGSPFPEVAESVQEELDKYRAQEEEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLDHIKSRKLDVYFEYEEKLMSKSTL-DKSLLDIITDPDAGTPEDKMRLFLIYYITSQQPP-------SEGDLEQYKKALIDAGCDLSPLNYIKQ--------WNKVLRMQTFKTTCALFLSLFSRVMNTGSQFVMEGVKNLVLKQHNLPVTRILDNLMDMKSNPETDDYRYFDPKMLRGSERYD-PTLRTR---AIVFVVGGGNYIEYQNLVDYAK-------AKQGKRVLYGCSELFSAAQFTKQLSQLGQ 567
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Cavefish
Match: vps45 (pleckstrin homology domain-containing family O member 1-A-like [Source:NCBI gene;Acc:103034895]) HSP 1 Score: 104.375 bits (259), Expect = 5.848e-23 Identity = 139/577 (24.09%), Postives = 252/577 (43.67%), Query Frame = 2
Query: 131 KVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSE-REPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCP-PGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFER----PLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVN---IPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLE-VIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKL--QARQPLHEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYF--MEGVKNFVAKKHKLPFTKILHNLMEQV--SDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVE 1813
KVL+ DK I+S ++TQ + V + I+S+ RE + + AI F+ PT EN+ L +++ Y Y+I F + I++ +++ LA ++D ++++ + Y +FI + LF L+ L G + I+ + GL SV + + P+IR + A+ +A ++ + F + PLL+ILDRS D TP+ + WTYQA+VH++L + N ++ +P +K L ENDEF+ + + EI I+ +E K K K +L+S + D K+S TVS H + L+ + ER+L E+E++L Q ++++ +L +P D +RL++L L ++ + + D EL++ S+ ++ A+ R+ +L + T ++ ++ +F ++GV+N V +H+ +LH+ ++Q+ ++ F Y P L+ QD IVF+IGG Y E
Sbjct: 23 KVLLMDKETTSIVSMVYTQSEILQKEVYLFERIDSQNRENMKHLKAICFLRPTKENVENLIQELHRPKYSVYFIYFSNVISKSEVKALA----EADEQEVVAEVQEFYGDFIAVNPHLFSLN-----------LQGVVRGRSWEPTILPRVTQGLTSVLLALKKCPMIRYQLSSDMAKRLA------------------------ESVKQIITKEYELFDFRKTEVPPLLLILDRSDDAITPLLNQWTYQAMVHELLGLNNNRIDLSRVPGISKDLREVVLSAENDEFYANNLYLNFGEIGTNIKNLMEDFQKKKPKGQQKLESISDMKAFVDNYPQFKKMSGTVSK-------------HVTVVGELSRLVSERQLMEVSEVEQELACQNDHSSAQQNVRRLLQNPRVAELDAVRLVMLYALRYERHSSSMLPSLMD-ELNRRG----VSEKHCKMVQAMIDYGGKRVRGTDLITA------------TDAVAITKQFFKGLKGVEN-VYTQHQ----PLLHDTLDQLIKGRLKDSQFPYLGPS-----------SLRDRPQDIIVFIIGGATYEE 514
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Cavefish
Match: vps45 (pleckstrin homology domain-containing family O member 1-A-like [Source:NCBI gene;Acc:103034895]) HSP 1 Score: 95.9005 bits (237), Expect = 2.444e-20 Identity = 77/289 (26.64%), Postives = 134/289 (46.37%), Query Frame = 2
Query: 131 KVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSE-REPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCP-PGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFER----PLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVN---IPSQTKKTNSYELWCENDEFW 970
KVL+ DK I+S ++TQ + V + I+S+ RE + + AI F+ PT EN+ L +++ Y Y+I F + I++ +++ LA ++D ++++ + Y +FI + LF L+ L G + I+ + GL SV + + P+IR + A+ +A ++ + F + PLL+ILDRS D TP+ + WTYQA+VH++L + N ++ +P +K L ENDEF+
Sbjct: 23 KVLLMDKETTSIVSMVYTQSEILQKEVYLFERIDSQNRENMKHLKAICFLRPTKENVENLIQELHRPKYSVYFIYFSNVISKSEVKALA----EADEQEVVAEVQEFYGDFIAVNPHLFSLN-----------LQGVVRGRSWEPTILPRVTQGLTSVLLALKKCPMIRYQLSSDMAKRLA------------------------ESVKQIITKEYELFDFRKTEVPPLLLILDRSDDAITPLLNQWTYQAMVHELLGLNNNRIDLSRVPGISKDLREVVLSAENDEFY 272
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Cavefish
Match: stxbp2 (syntaxin binding protein 2 [Source:NCBI gene;Acc:103039197]) HSP 1 Score: 88.9669 bits (219), Expect = 5.211e-18 Identity = 81/326 (24.85%), Postives = 140/326 (42.94%), Query Frame = 2
Query: 98 ITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNG--IYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQY-TNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSH---LSFERPLLVILDRSLDLATPINHPWTYQALVHDILNI-----KFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKS 1042
+ K + D WKVLI D + I+S+ + GVTI +IN REPI + AIYF+ P S++++ L D + Y++ +I F E ++ V ++ K + F+ E ++ L D + YS G ++ E + ++ + + ++C T+ P IR G N + + + L+ H + S R L+I+DR D +P+ H T+QA+V+D+L I ++ T + K L E+D+ W RH IADV ++ E+++S
Sbjct: 18 VLKSIKKDGEWKVLIVDHISMRILSSCCKMSDIMAEGVTIVEDINKRREPISSLEAIYFISPVSKSVDGLISDFKDSAFTYKAAHIFFT-----ENCPDGLFAKIGKSRVARVIKTLKEINVAFLPYESQVYSLDDPSLLHVVYSP---TGSNEDERTKKMEAVAEQIATLCDTLKEYPAIRYRQG-------------------PKENVALAEMVLDRLNAHKADNPSMGEGTDKARSQLLIVDRGYDPISPLLHELTFQAMVYDLLEIDQDIYRYETTGVGENKMKEV---LLDEDDDLWVQLRHM---HIADVTKKVTEMLRS 310
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Cavefish
Match: stxbp1a (syntaxin binding protein 1 [Source:NCBI gene;Acc:103024456]) HSP 1 Score: 78.9518 bits (193), Expect = 6.825e-15 Identity = 76/332 (22.89%), Postives = 144/332 (43.37%), Query Frame = 2
Query: 128 WKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLC---KDIDNGIYESYYINFI----SPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSF---ERPLLVILDRSLDLATPINHPWTYQALVHDILNI-----KFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSM 1078
WK LI D+ + ++S+ + G+TI +IN REP+P + AIY + PT +++ L KD + Y + ++ F P+ E ++ A + ++N+I+ F Y E +F L D+ S+ S + Q + ++ + + L ++C T+ P +R N+ + L L + + + R L+ILDR+ D +P+ H T+QA+ +D+L I K+ T + +K L E+D+ W RHK + E++ + + L+ + ++ K++M
Sbjct: 28 WKALIVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPLPTLEAIYLITPTEKSVQTLVGDFKDPHSSKYRAAHVFFTDSCPDPLFNEVVKSRASKCIK--TLNEINIAFLPY------ESQVFSL-DNPDAFQSFYSPHKT----QMKNPVMERLAEQLATLCATLKEYPAVR-------------------YRGEYKDNATLAQLVQDKLDAYKADDPTMGEGPDKARSQLIILDRAFDPVSPVLHELTFQAMGYDLLPIENDVYKYETSGMGDSREKEV---LLHEDDDLWVSLRHKHIAEVSQEVTKSLKEFSASKRMNTGEKTTM 324
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: vps45 (vacuolar protein sorting 45 homolog [Source:ZFIN;Acc:ZDB-GENE-060503-526]) HSP 1 Score: 91.6633 bits (226), Expect = 1.163e-19 Identity = 94/406 (23.15%), Postives = 175/406 (43.10%), Query Frame = 2
Query: 131 KVLICDKHGLDIISTLFTQKSLRDLGVTISLNINS-EREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFER----PLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVN---IPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHE---KSLLDMLSSP 1315
KVL+ DK I+S +++Q + V + ++S REP+ + A+ F+ P E+I L +++ Y Y+I F + +++ ++ LA ++D + ++ + Y ++I + +F L+ L G + ++ GL +V +++ PVIR +++E+ + + S + F + PLL++LDR+ D TP+ + WTYQA+VH++L I N ++ +P + L E+D+F+ + EI I+ +E + K K +++S + + K+S TVS H + L+ + R L ELE++L A Q H +SL ML P
Sbjct: 23 KVLLMDKDTTSIVSMVYSQSEILQKEVYLFERVDSVNREPMKHLKAVCFIRPVKESIELLVQELRRPKYGLYFIYFSNVVSKSDVKTLA----EADEHEVVRELKEFYADYIAISPHIFSLN-----------LTGCSQGRSWDPVLLTRATLGLTAVLLSLKKCPVIRYQ--HSSELARRLA---------------------ECVKQMISKDAALFDFRKTDVPPLLLVLDRNDDAITPLLNQWTYQAMVHELLGINNNRIDLSSVPGVGRDLKEVVLSSEHDDFYASNMYLNFGEIGTNIKNLMEEFQKKSKSSQKVESIADMKAFVENYPQFKKMSGTVSK-------------HVTVVGELSRLVASRSLLSVSELEQEL-ACQSDHSSALQSLRRMLQQP 376
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: stxbp1a (syntaxin binding protein 1a [Source:ZFIN;Acc:ZDB-GENE-050626-106]) HSP 1 Score: 77.0258 bits (188), Expect = 5.246e-15 Identity = 78/320 (24.38%), Postives = 137/320 (42.81%), Query Frame = 2
Query: 128 WKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNG---IYESYYINFISPINREKLEQLAYSTF--QSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYE--LWCENDEFWRDERHKPLPEIADVIQQGLEVIK--SKEKEMA 1060
WKVL+ D+ + ++S+ + G+TI +IN REPIP + A+Y + P+ +++ L D + Y+ ++ F ++L S + ++ +I+ F Y E +F L D S+ S A + ++ + I ++C T+ P +R G+ A + K + + N T+ D +S L+I+DR D +P+ H T+QA+ +D+L I+ + + N + L E+D+ W RHK IADV Q + +K S K MA
Sbjct: 29 WKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPIPSLEALYLITPSEKSVRALINDFKDASIFKYKGAHVFFTDSCPEALFKELGKSRVAKNTKALQEINIAFLPY------ESQVFSL-DAPEAFQSFYSPQKASVRNHMMERLAEQIA----TLCATLQEYPAVRY-RGDYANNTYLAQLVQDKLDAYKADN--------PTMGDGPDKGRSQ-------LLIIDRGFDPTSPVLHELTFQAMAYDLLPIENDVYKYDTSGMGENHMKEVLLDEDDDLWMQLRHK---HIADVSQDVTKSLKEFSSSKRMA 318
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Yeast
Match: SLY1 (Hydrophilic protein involved in ER/Golgi vesicle trafficking; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex [Source:SGD;Acc:S000002597]) HSP 1 Score: 271.166 bits (692), Expect = 4.644e-82 Identity = 197/645 (30.54%), Postives = 324/645 (50.23%), Query Frame = 2
Query: 125 LWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKK------------TNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTN----KLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTAN---DKXXXXXXXXXYS-SGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSH-RLHSQNLSSKQVSHQTKSS------------GLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVE-----TDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLG 1945
+WKVLI D IS++ L G+T+ I +R P+PDVPAIYFV PT ENI+ + D+ + Y +YINF S + R LE LA + ++I +++DQY +FI E +LF L S +Y +LN +++EI + +I DGLF+ +TI +IP+IR G AE++A + + ++T S +S Q + S ER +L+ILDR++D A+ +H W YQ +V DI + NTV IP ++K+ T Y++ ND FW + H P PE A+ ++ L K +E A++ G+ SD+ ++N ++ + V L KK ++ H NI L Q++ + LD +FE+E+ + + LD+L DG N DKLR ++ L S +G P + V+++ + + +D DI+ + V +R +L + +L +K + + S+ GL + + G+K + +K +P T ++ +M+ ++ + TD++ Y DPK+ R + R S+ ++VFV+GGGNY+EYQNL E+ + Q KK+ YG T + +FL ++S LG
Sbjct: 52 IWKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENIDIIVNDLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQVYDQYLDFIVTEPELFSLE----ISNAYLTLNDPKTTEEEITGLCANIADGLFNTVLTINSIPIIRAAKGGPAEIIA------------EKLGTKLRDFVINTNSSSTSTLQGNDSLERGVLIILDRNIDFASMFSHSWIYQCMVFDIFKLSRNTVTIPLESKENGTDNTTAKPLATKKYDIE-PNDFFWMENSHLPFPEAAENVEAALNTYK---EEAAEITRKTGVTNISDLDPNSNNDTVQIQEVVKKLPELTAKKNTIDTHMNIFAALLSQLESKSLDTFFEVEQDPGSTK--TRSRFLDILK--DGKTNNLEDKLRSFIVLYLTSTTGLPKDFVQNVEN--------YFKENDYDINALKYVYKLREFMQLSNMSLQNKSLEDGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIKKLLPEKKTIPITNVVDAIMDPLNSSQKNLETTDSYLYIDPKITRGSHTRKPKR--QSYNKSLVFVVGGGNYLEYQNLQEWAHS-----QLHNPKKVMYGSTAITTPAEFLNEISRLG 657
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Yeast
Match: VPS45 (Protein of the Sec1p/Munc-18 family; essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment [Source:SGD;Acc:S000003063]) HSP 1 Score: 94.3597 bits (233), Expect = 1.191e-20 Identity = 143/579 (24.70%), Postives = 245/579 (42.31%), Query Frame = 2
Query: 110 VNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNI-NSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVN---IPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDP--DISVMAAVRHVRSHRLHSQNLSSKQVSHQTKS--SGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYR---SADGDNLPRLKSSFQDAIVFVIGGGNYVE 1813
VN + KVL+ DK+ IS TQ L + + I N +RE + + +V PT E + L +++ N Y Y I F + +++ +LE+LA +SD + ++K+ + + +F L DLF +S N S+ + NS+V SV +++ P IR A + +RL K++ + + + F M + P+L+ILDR+ D TP+ PWTYQ+++++ + IK N V+ +P K L + D F+RD + E+ D ++Q + K K + +Q+ S + + KLS V+ H I L Q+K + + E+E+ L A +E+ D++ A DK L LA +YS + +S K + QL + P D++ + L S+ Q +H + L +F +S+ V +H + +L +L + + D FK D + +R + ++P QD I+FVIGG Y E
Sbjct: 26 VNEHQRIKVLLLDKNTTPTISLCATQSELLKHEIYLVERIENEQREVSRHLRCLVYVKPTEETLQHLLRELRNPRYGEYQIFFSNIVSKSQLERLA----ESDDLEAVTKVEEIFQDFFILNQDLFSFDLQPREFLS----NKLVWSEGGLTKCTNSLV----SVLLSLKIKPDIRY---EGASKICERLAKEVSYEIGKNERTFFDFPVMDST---------------PVLLILDRNTDPITPLLQPWTYQSMINEYIGIKRNIVDLSKVPRIDKDLEKVTLSSKQDAFFRDTMYLNFGELGDKVKQYVTTYKDKTQTNSQINSIEDIKNFIEKYPEFRKLSGNVAK-------------HMAIVGELDRQLKIKNIWEISEIEQNLSAHDA-NEEDFSDLIKLLQNEAVDKYYKLKLACIYSLNNQTSSDK------IRQLVEILSQQLPPEDVNFFHKFKS-----LFSRQDKMTQSNHDKDDILTELARRF--NSRMNSKSNTAENVYMQHIPEISSLLTDLSKNA--LFRDRFKEIDTQGHRVIGNQQSKDIP------QDVILFVIGGVTYEE 539
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO32378 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SV88]) HSP 1 Score: 504.597 bits (1298), Expect = 1.211e-171 Identity = 293/669 (43.80%), Postives = 430/669 (64.28%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI------------------PSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD------ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSG---SPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSH-RLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGRN 1951
MA ++R ++I+ALK MLN N P+ K V + +WKVL+ D+ G DIIS L T K LRDLGVT+ L +++ER+PIP+VPA+YFV+PT EN+ ++C+D N +YESYY+NFI+ I+R +LE+LA Q++ VNQISK++DQY NFI LED++F + ++SY +LN D +I+ + +++VD LF + ++GT+P+IRCP GNAAE+VA+ LDKKL++NLRDSRNSLF+ +D SG +SF+RP+LVILDR++DL TP++H WTYQAL HD+L + N V + P Q K +Y+L D+FW + P P +A+ I++ L K+ E+E+ +LK+ MG+ ++ DST KL+ VSSL LEKK+L+++HTNIAT L D IK RKLDI+FE EEK+ ++ L +KS+L+++ PD GT DK L L + Y SG SPA E DQ S + + + ++ ++ ++ ++ + L S Q S +F++ ++ + MEGVKN V LP T+IL +ME S+ E ++F+YFDPK+ R D ++PR K+ FQ+AIVF++GGGN++EYQNL++Y K +S TKK+ YG +E+LN QF+ QLS LG +
Sbjct: 1 MAASVRAKQIEALKRMLNLNKPVGKSVAAEPVWKVLVYDRFGQDIISPLLTVKELRDLGVTLHLLLHTERDPIPEVPAVYFVMPTEENVKRICQDCRNQLYESYYLNFITAISRHRLEELATVALQTNCVNQISKVYDQYLNFISLEDEMFTTRFQERDAISYYALNRPDAKDTDIEMLRDALVDSLFCLLASLGTVPIIRCPKGNAAEIVAEALDKKLRENLRDSRNSLFT-------TDIPSG---QISFQRPVLVILDRNMDLCTPLHHTWTYQALAHDVLELHLNRVVVRETAPQVNDDHPDAHHRHPKQV-KIKTYDLH-NTDKFWNSHKGSPFPNVAESIEKELNEYKASEEEVKRLKNVMGIDESNEEVMGEIFADSTAKLTSAVSSLPELLEKKRLIDMHTNIATALLDHIKARKLDIFFETEEKIMSKSTL-DKSILEIIQDPDAGTPEDK--LRLFIIYYVSGPTMSPA---------EFDQYASALQACGVQSAALSYIKKWKAFTKITTAPLQSGG-GGQNTYSAMFSRIMNTGSQFVMEGVKNLVVGNKNLPVTRILDAVMENKSNPEVEDFRYFDPKMLRVTDSSSIPRNKTPFQEAIVFMVGGGNFIEYQNLMDYAK------RSSGTKKVFYGASEVLNASQFIKQLSRLGED 638
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO39542 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9U5]) HSP 1 Score: 101.293 bits (251), Expect = 2.001e-22 Identity = 146/631 (23.14%), Postives = 257/631 (40.73%), Query Frame = 2
Query: 131 KVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSE-REPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERP----LLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI---PSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQN--------LSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSF-------------QDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLS 1936
KVL+ DK I+S +++Q + V + +++ RE + + AI F+ PT ENI+ LC ++ + Y YYI F + + + + LA ++D + ++ + Y ++ + +F L+ S +S+ G G+ D ID++ S +G+ ++ +++ P+IR ++S + + +G F RP LL+ILDR D TP+ + WTYQA+VH++L I+ N V++ P + + E+DEF++ + EI I+ ++ + K +L+S + + K+S TVS H + + L+ + +R L E+E++L A Q H +L ++ ANDK+ ELD L + ++ A+R+ R H+ N L+ + V Q K I + G F K L T+ + ++ V ++ T + P L + DG RLK + QD IVF++GG Y E Q + K K+ G T + N FL ++S
Sbjct: 23 KVLLMDKETTGIVSMVYSQTEVLQKEVYLFERVDTPGRETMKHLKAICFLRPTPENIDHLCSELKSPKYGVYYIYFSNFVPKASIRALA----EADDQEVVREVQEYYADYFAISPHVFSLN-------SPASMKG-GQWD--IDSLDRS-CEGVLALLLSLKKCPMIR-----------------------YQQSSEVAHRLAERIRQKINGEAKLFDFRRPDVPPLLLILDRRDDPVTPLLNQWTYQAMVHELLTIRNNRVDLSKCPDVARDLQEVVMSAEHDEFYQKNMYLNFGEIGQNIKTLMDDFQQHVKSNQKLESISDMKNFVENYPQFKKMSGTVSK-------------HVTMVSELSRLVSDRCLLDVSEIEQEL-ACQNDHSAALQNIRRL---MANDKVS-----------------------ELDLL---------RVVMIYALRYER----HTNNDVSTLVNMLARRGVGEQYKR---LVPAIVQYAGRSVRGSDLFGQNKTPLSLTRKILKGLKGVENIYTQH----APLLSETIDGLIKGRLKDAQFPYMGHAQLRDRPQDIIVFIVGGATYEEAQAVYNINKTQPGI-------KVILGGTTIHNCRSFLEEVS 548
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO43369 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYS2]) HSP 1 Score: 87.0409 bits (214), Expect = 6.314e-18 Identity = 79/325 (24.31%), Postives = 143/325 (44.00%), Query Frame = 2
Query: 83 NFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGI--YESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEK 1051
N P+ KV WKVL+ D + ++S+ L ++G+TI N++ +REP+ + AIY + P + + ++ +D D+ Y+S +I F + +L + V + + + F+ E+ +F L + T +S + + I + L ++C ++G P IR P N +MV N + + L + D S G + + L++LDR D +P+ H TYQA+ +D++NIK + K + ENDE W RH + +++ I + ++ KEK
Sbjct: 9 NVFKPLHKVGE----WKVLVVDHLSMRMVSSCLKMHDLLEVGITIVENVHIQREPLNRLEAIYLITPDEKVLEEVIEDFDSFFLTYKSAHIFFTEVCPDHLMTKL--HQIRKCKVIIVKTLKEIDIAFLPCEEQVFSLDNPSTFDRFFSPAPTS--------LLPQKIAEQLATLCASLGEFPSIRYKPDN-PKMVG-------------FANQVKARLDVYKRDDPSIGEGRYPA----QLILLDRGFDPISPLLHELTYQAMAYDLINIKNDVF------KYNFNLFFLLENDEMWVKLRHLHIADVSRKIPEEIKEFSEKEK 295
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO43368 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYS1]) HSP 1 Score: 65.4698 bits (158), Expect = 3.424e-11 Identity = 70/323 (21.67%), Postives = 128/323 (39.63%), Query Frame = 2
Query: 137 LICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNG--IYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELW-------CENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSM 1078
L+ D +IS+ L D GVT+ N+ REP+P + AIY + P ++I+ L D Y+ ++ F L QL ++ +I+ F Y E +F L D G + G ++E + + + L ++C T+G P IR + + + G + +D + + R L+ILDR+ D +P+ H T QA+ +D+L+I + + T ++ +ND W RH + +++ I ++ K++ KS++
Sbjct: 1 LVLDHLSTRMISSCVKMHDLIDNGVTVVENLEKRREPLPQLEAIYILTPEEDSISLLVADFKEYPLKYKGAHLFFTEVCPDSLLVQLQGIKRFIKTLKEINIAFLPY------ESQVFSL-DSTQG---FGKFYAPGVENKERIQYLERMAEQLATLCATLGEYPSIR---------------FRHESPKLTEFAHIVQGRLDAYKADDPTMGEGSAHKHRSQLIILDRAFDPVSPLLHELTLQAMAYDLLDITNDVYKYGCSARVTVPILIFIFSGVSDADNDPMWVKLRHLHIADVSRKISDEIKEFAGKKRMSTTEKSTL 298
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO28225 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T727]) HSP 1 Score: 55.0694 bits (131), Expect = 6.047e-10 Identity = 37/68 (54.41%), Postives = 54/68 (79.41%), Query Frame = 2
Query: 524 SLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFS 727
+LN D +I+ + +++VD LF + ++GT+P+IRCP GNAAE+VA+ LDKKL++NLRDSRNSLF+
Sbjct: 1 ALNRPDAKDTDIEMLRDALVDSLFCLLASLGTVPIIRCPKGNAAEIVAEALDKKLRENLRDSRNSLFT 68
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Medaka
Match: scfd1 (sec1 family domain containing 1 [Source:NCBI gene;Acc:101160449]) HSP 1 Score: 525.398 bits (1352), Expect = 1.541e-179 Identity = 297/658 (45.14%), Postives = 441/658 (67.02%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI-------PS------QTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGR 1948
MA ++R ++ AL+ MLNFN+P K + +WKVLI D+ G DIIS L + K LRD+G+T+ L ++S+R+PIPDVPAIYF++PT ENI+++C+D+ N +YESYY+NFIS I+R KLE +A + ++ V+Q++K+FDQY NFI LED++F+L +SY ++N A D +++AI++SIVD LF VT+G +P+IRCP GNAAEMVA +LDKKL++NLRD+RNSLF+G MS SF+RPL V+ DR++D+ATP++H WTYQAL+HD+L+ N V + PS + K SY+L D+FW+ + P PE+A+ +Q+ L+ +++E E+ LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + D IK RKLD+YFE EEKL ++ L +KSLLD+++ PD GT DK+RL L+ + + +P ++ +L+Q + + D+S + ++ ++ + + + K GLF++ ++ + MEGVKN V K+H LP T+IL NLME S ETD+++YFDPK+ R ++ ++PR K+ FQ+AIVFV+GGGNY+EYQNL++YTK S +K+ YGC+EL N QF+ QLS LG+
Sbjct: 1 MAASVREKQTVALRRMLNFNTPPLKNNAAEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAIYFLMPTEENIDRICQDLRNQLYESYYLNFISAISRSKLEDIASAALAANVVSQVTKVFDQYLNFITLEDEMFILCHQNKELISYHAINRADIQDTDMEAIMDSIVDSLFCFFVTLGAVPIIRCPRGNAAEMVAVKLDKKLRENLRDARNSLFTGDSMSA---------GQFSFQRPLFVLADRNMDMATPLHHSWTYQALIHDVLDFHLNRVVMEEGSSMEPSPGGARPKKKSKKSYDLTAA-DKFWQKHKGSPFPEVAESVQEELDSYRAQEDEVKHLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLDHIKSRKLDVYFEYEEKLLSKSNL-DKSLLDIITDPDAGTPEDKMRLFLIYYITAQQAP-------SELDLEQYRKALLDAGCDLSPLNYIKQWKAFTKMAN--PANYGNSGVKPMGLFSRVMNTGSQFVMEGVKNLVLKQHNLPVTRILDNLMEMKSHPETDDYRYFDPKMLRGSES-SVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYTK-------SKPGRKVVYGCSELFNAAQFMKQLSQLGQ 630
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Medaka
Match: scfd1 (sec1 family domain containing 1 [Source:NCBI gene;Acc:101160449]) HSP 1 Score: 318.546 bits (815), Expect = 4.714e-101 Identity = 210/508 (41.34%), Postives = 316/508 (62.20%), Query Frame = 2
Query: 479 LFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNI-------PS------QTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSD-----ITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPD-GTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRS--HRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKH--KLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQL 1933
+F+L +SY ++N A D +++AI++SIVD LF VT+G +P+IRCP GNAAEMVA +LDKKL++NLRD+RNSLF+G MS SF+RPL V+ DR++D+ATP++H WTYQAL+HD+L+ N V + PS + K SY+L D+FW+ + P PE+A+ +Q+ L+ +++E E+ LKS MGL G+ + ++D+T KL+ VSSL LEKK+L+++HTN+AT + D IK RKLD+YFE EEKL ++ L +KSLLD+++ PD GT DK+RL L+ + + +P ++ +L+Q + + D+S + ++ ++ + N + V K GLF++ ++ + MEGVKN V K P T L+ VS ETD+++YFDPK+ R ++ ++PR K+ FQ+AIVFV+GGGNY+EYQNL++YTK S +K+ YGC+EL N QF+ Q+
Sbjct: 1 MFILCHQNKELISYHAINRADIQDTDMEAIMDSIVDSLFCFFVTLGAVPIIRCPRGNAAEMVAVKLDKKLRENLRDARNSLFTGDSMSA---------GQFSFQRPLFVLADRNMDMATPLHHSWTYQALIHDVLDFHLNRVVMEEGSSMEPSPGGARPKKKSKKSYDL-TAADKFWQKHKGSPFPEVAESVQEELDSYRAQEDEVKHLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLDHIKSRKLDVYFEYEEKLLSKSNL-DKSLLDIITDPDAGTPEDKMRLFLIYYITAQQAP-------SELDLEQYRKALLDAGCDLSPLNYIKQWKAFTKMANPANYGNSGV----KPMGLFSRVMNTGSQFVMEGVKNLVLKHWCPGKPLTCDPRFLLHFVSLQETDDYRYFDPKMLRGSES-SVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYTK-------SKPGRKVVYGCSELFNAAQFMKQV 478
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Medaka
Match: vps45 (vacuolar protein sorting 45 homolog [Source:NCBI gene;Acc:101171176]) HSP 1 Score: 104.76 bits (260), Expect = 3.696e-23 Identity = 98/386 (25.39%), Postives = 171/386 (44.30%), Query Frame = 2
Query: 131 KVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSE-REPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFER----PLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVN---IPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKE-KEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKL 1261
KVL+ DK I+S ++TQ + V + I+S+ R+ + + AI F+ PT EN+ L +++ Y Y+I F + I++ +++ LA ++D ++++ + Y +FI + LF L+ L G + ++++ GL SV + + P+IR +S S ++ + F + PLL+ILDRS D TP+ + WTYQA+VH++L + N ++ +P +K L ENDEF+ + + EI I+ +E + K K +L+S + D K+S TVS H + L+ + ERKL E+E++L
Sbjct: 23 KVLLMDKETTSIVSVVYTQSEILQKEVYLFERIDSQSRDSMKHLKAICFLRPTKENVQHLIQELRRPKYSIYFIYFSNVISKSEIKVLA----EADEQEVVAEVQEFYGDFIAVNPHLFSLN-----------LQGVARGRSWEPSMLSRCTQGLTSVLLALKKCPMIR-----------------------YQLSSDMSKRLAESVKQIITKEYELFDFRKTEVPPLLLILDRSDDAITPLLNQWTYQAMVHELLGLNNNRIDLSRVPGISKDLKEVVLSAENDEFYANNLYLNFGEIGTNIKNLMEDFQKKRPKGQEKLESISDMKAFVDNYPQFKKMSGTVSK-------------HVTVVGELSRLVSERKLMEVSEVEQEL 357
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Medaka
Match: stxbp2 (syntaxin-binding protein 2 [Source:NCBI gene;Acc:101164402]) HSP 1 Score: 87.8113 bits (216), Expect = 1.165e-17 Identity = 78/323 (24.15%), Postives = 140/323 (43.34%), Query Frame = 2
Query: 98 ITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGI--YESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQY-TNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIK-----FNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKS 1042
+ K V D WKVLI D + I+S+ + GVTI +IN REPI + AIY + P +++ L D + + Y++ +I F + ++ S V ++ K + F+ E +F L S+ S G+ + + D +I ++ + + ++C T+ P +R G + + S+ G + R L+I+DR D +P+ H T+QA+ +D+L+IK + T + + ++ L E+DE W RH+ IADV ++ E+++S
Sbjct: 41 VIKSVKKDGEWKVLIVDHMSMRILSSCCKMSDILAEGVTIVEDINKCREPISSLEAIYLISPMEKSVKALINDFKDTVFTYKAAHIFFTDACSDSLFAEIGRS-----RVAKVIKTLKEINVAFLPYESQVFSL----DSPSSFKSFYGSRPCESK-DRMIENMAEQIATLCDTLKEFPAVRYRKGPEENAKLAEEVSRRLTAHKADNPSMGEGADKA----------------RSQLLIVDRGFDPISPVLHELTFQAMAYDLLDIKQDIYTYQTTGVGNSKQRE---VLLDEDDELWVQLRHQ---HIADVTKKVTELLRS 331
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Medaka
Match: stxbp1b (syntaxin-binding protein 1 [Source:NCBI gene;Acc:101159753]) HSP 1 Score: 81.6481 bits (200), Expect = 3.634e-16 Identity = 75/322 (23.29%), Postives = 140/322 (43.48%), Query Frame = 2
Query: 128 WKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDI---DNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIP-SQTKKTNSYELWC-ENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSM 1078
WKVL+ DK + ++S+ + G+TI +I REP+P + AIY + P+ E++ L +D N Y + ++ F I + L L + S ++ +++I + F+ E +F L + YS KS+ ++ + + ++C T+ P +R G+ + L L D + G R L+I+DR D +P+ H T QA+ +D+L I+ + + S +T E+ E+D+ W RHK + E++ + + L+ + +K K++M
Sbjct: 14 WKVLVVDKLSMKMVSSCCKMTDIMSEGITIVEDITKRREPLPSMEAIYLITPSDESVEGLIEDFRDPQNPRYRAAHVFFTDTIP-DSLFGLLTKSRASKAMKALTEI---HIAFLPYESQVFSLDKAEAFQDFYSPFKADVKSN-----MLERCAEQIATMCATLKEYPGVRY-RGDYKDCAV-------------LAQMLQEKLDGYKADDPTMGEGPDKC--RTQLLIVDRGFDPVSPLLHELTLQAMAYDLLGIENDVYSFETSGMGETRMKEVVLDEDDDLWLSLRHKHIAEVSTAVTRSLKEFSASKKMNTGEKTTM 310
BLAST of sec1 family domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000044570.1 (SMESG000044570.1) HSP 1 Score: 1234.94 bits (3194), Expect = 0.000e+0 Identity = 640/640 (100.00%), Postives = 640/640 (100.00%), Query Frame = 2
Query: 32 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGRN 1951
MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAKRLDKKLKDNLRDSRNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSLKGFLEKKKLLEIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKLRLLLLALLYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGRN
Sbjct: 1 MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAKRLDKKLKDNLRDSRNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSLKGFLEKKKLLEIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHEKSLLDMLSSPDGTANDKLRLLLLALLYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQLSMLGRN 640
BLAST of sec1 family domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000046314.1 (SMESG000046314.1) HSP 1 Score: 88.1965 bits (217), Expect = 5.876e-18 Identity = 146/615 (23.74%), Postives = 275/615 (44.72%), Query Frame = 2
Query: 107 VVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFI-CLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPLHE-----KSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQL 1933
+ N D KVL+ D+ L +++++F+ + V + I S RE + + I ++ PT N+N L K++ N Y+SY I+F ++++ L+ LA ++D + I + + +F C D F+ H + N + EI ++ +I DG+ S+ + + P IR N++E VA+RL +KL+ ++ N S S+L L+I+DR LD TP+ + WTYQA+++++L + N VNI + + L ++DEF+ + EI I+ +E +++K A++ S + + S K+S VS H I + ++ I + KL E E+ + Q + + + D+L + + +D +RL+LL L P ++ + L Q S+ +I ++ + S + S NL ++++ S LF ++GV+N + L + N+ QV++ + + + P + + ++ + D I+FV+GG + E +L + N Q K + G T++LN FLL++
Sbjct: 2 IKNDDNGMKVLMLDEETLKVVNSVFSMSEIMKFDVYLCERITSPRENLLYLNCICYLRPTVRNVNLLEKELRNPHYKSYDIHFSHSLSKQYLKLLA----EADHFELVKNIQESFADFYPC---DPFLFHLNLK--------NVIINREWEISSLSRTI-DGITSLLLALKIFPQIRYQ--NSSE-VARRLAEKLRIHISREANLFESKQNRSSL-----------------LLIIDRRLDPVTPLLNQWTYQAMINELLEVDNNCVNI--HEGEISEINLSPDHDEFYHQNLYNNFGEICSNIKCFMEELQNKSSNQAKIDSIEDMKMFIENYPSFRKMSAKVSQ-------------HVLIISEISKIINKNKLLRVSECEQNIVNHQMIDNHNSCVQMIKDLLGNSEIKKHDAIRLVLLYALKYDRHPRKETSNLMNLLLKQ----SGVSEMEIQIIRILMEYGS--IKSPNLFKEKINSLGIPSNLFKS---------IKGVENIYTQHQPL-----ISNIANQVNEQKLNEVLF--PYISGCSPSNH------KYTDLIIFVVGGVTFEE--SLAIHNIN-----QQISGKNVILGGTQILNYHSFLLEV 530
BLAST of sec1 family domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000046309.1 (SMESG000046309.1) HSP 1 Score: 88.1965 bits (217), Expect = 7.140e-18 Identity = 142/613 (23.16%), Postives = 270/613 (44.05%), Query Frame = 2
Query: 98 ITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGIYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITDSTNKLSDTVSSXXXXXXXXXXXXIHTNIATHLADQIKERKLDIYFELEEKLQARQPL-HEKSLLDMLSSPDGTANDKXXXXXXXXXYSSGSPANSVKDITDQELDQLCSFIHSSDPDISVMAAVRHVRSHRLHSQNLSSKQVSHQTKSSGLFTKFISHSQAYFMEGVKNFVAKKHKLPFTKILHNLMEQVSDVETDNFKYFDPKLYRSADGDNLPRLKSSFQDAIVFVIGGGNYVEYQNLIEYTKNHKSTYQSDRTKKISYGCTELLNGEQFLLQL 1933
I + N D KVL+ D+ L +++++F+ + V + I S RE + + I ++ PT N+N L K++ N Y+SY I+F ++++ L+ LA ++D + I + + +F + LF L+ N + EI ++ +I DG+ S+ + + P IR N++E VA+RL +KL+ ++ N S S+L L+I+DR LD TP+ + WTYQA+++++L + N VNI + + L ++DEF+ + EI I+ +E +++K A++ S + + S K+S VS H I + ++ I + KL E E+ + Q + + S + M+ G + K + +L + + T ++ L S+ +I ++ + S + S NL ++++ S LF ++GV+N + L + N+ QV++ + + + P + + ++ + D I+FV+GG + E +L + N Q K + G T++LN FLL++
Sbjct: 12 INMIKNDDNGMKVLMLDEETLKVVNSVFSMSEIMKFDVYLCERITSPRENLLYLNCICYLRPTVRNVNLLEKELRNPHYKSYDIHFSHSLSKQYLKLLA----EADHFELVKNIQESFADFYPCDPFLFHLNLK----------NVIINREWEISSLSRTI-DGITSLLLALKIFPQIRYQ--NSSE-VARRLAEKLRIHISREANLFESKQNRSSL-----------------LLIIDRRLDPVTPLLNQWTYQAMINELLEVDNNCVNI--HEGEISEINLSPDHDEFYHQNLYNNFGEICSNIKCFMEELQNKSSNQAKIDSIEDMKMFIENYPSFRKMSAKVSQ-------------HVLIISEISKIINKNKLLRVSECEQNIVNHQMIDNHNSCVQMIKDLLGNSEIKKHDAIRLVLLYALKYDRHPRKETSNLMNLLLKQSGVSEMEIQIIRILMEYGS--IKSPNLFKEKINSLGIPSNLFKS---------IKGVENIYTQHQPL-----ISNIANQVNEQKLNEVLF--PYISGCSPSNH------KYTDLIIFVVGGVTFEE--SLAIHNIN-----QQISGKNVILGGTQILNYHSFLLEV 543
BLAST of sec1 family domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000060160.1 (SMESG000060160.1) HSP 1 Score: 85.1149 bits (209), Expect = 5.796e-17 Identity = 77/316 (24.37%), Postives = 146/316 (46.20%), Query Frame = 2
Query: 119 DKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNG-IYESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSH-LSFERPLLVILDRSLDLATPINHPWTYQALVHDILNIKFNTVNIPS-QTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEM 1057
+ +W++L+ D++ II+ + L D GVT+ ++ REP+P + AIY + P + I + +D ++ +Y ++ F+ N E L + +S + N I + + F+ E LF + + G +++S N D + + + S+C + P I A+ A + +F +D +G H + +R +L+ILDR++D TPI H Q L +DIL+IK +T + T+K + +L END+ W RH + +++ ++ L+ + S +K +
Sbjct: 22 ENIWRILVLDEYSTQIIAKILKMHDLFDKGVTLVDDLAKRREPVP-LEAIYLISPEKKKIELMLRDFESTPVYSKAHVFFVDECNMENLRLIG----ESVAANYILTLKEMNIKFLISESQLFHFNFEH-GQNTFNSFNDLD------DDLSWEMARAIASLCDILNENPNIYYQTTEEAQRFA-----------IKVQQEMFK-------NDEENGFMGHTMHKDRSVLLILDRTVDPLTPILHDLHLQCLAYDILDIKNDTYIYKNFDTQKLVNVDL-SENDDLWIQLRHNHIADVSRILPVKLKQLASAQKSI 306
BLAST of sec1 family domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000013817.1 (SMESG000013817.1) HSP 1 Score: 80.1073 bits (196), Expect = 2.071e-15 Identity = 83/345 (24.06%), Postives = 146/345 (42.32%), Query Frame = 2
Query: 98 ITKVVNYDKLWKVLICDKHGLDIISTLFTQKSLRDLGVTISLNINSEREPIPDVPAIYFVLPTSENINKLCKDIDNGI--YESYYINFISPINREKLEQLAYSTFQSDSVNQISKIFDQYTNFICLEDDLFVLHDDKTGSMSYSSLNGAGKSDQEIDAIINSIVDGLFSVCVTIGTIPVIRCPPGNAAEMVAXXXXXXXXXXXXXXXNSLFSGLGMSTLSDHSSGTQSHLSF---ERPLLVILDRSLDLATPINHPWTYQALVHDILNIK---FNTVNIPSQTKKTNSYELWCENDEFWRDERHKPLPEIADVIQQGLEVIKSKEKEMAQLKSSMGLGGDSDITD 1108
+ + + + WKVLI DK +IS+ + + G+T+ +IN +RE +P + AIY + PT ++I L D Y++ ++ F E +L +S I + + F+ E +F L +T ++ G++ + I + + ++C T+ P IR + +N+ F+ L L + + S +R LVILDR D +P+ H T+QA+ +D++ I+ + +NI ++ L ENDE W + RH IA V Q + S+ K+ A K G G + + D
Sbjct: 14 VIRTIKKEGEWKVLIVDKLSTRMISSCCKMHDIMNEGITLVEDINKKREILP-LEAIYLITPTEKSIKSLMADFTGSKNQYKAAHVFFTEACPDESFNELC----KSPCAKYIKTLREINIAFLPYESRVFSLDSPETTQFYFNPNAKTGRTLH-----LERIAEQIATLCATLKEYPPIR-------------------YRAQWDKNAEFAQLVQQKLDAYKADDPSMGEGPFKDRSQLVILDRGFDPISPLLHELTFQAMSYDLIAIENDVYRYLNISGPEEREKEVVL-DENDELWVELRHL---HIAVVSNQ----VTSRLKKFADEKRMRGTGDKTTMRD 321 The following BLAST results are available for this feature:
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of sec1 family domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033902 ID=SMED30033902|Name=sec1 family domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2016bpback to top protein sequence of SMED30033902-orf-1 >SMED30033902-orf-1 ID=SMED30033902-orf-1|Name=SMED30033902-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=641bp MALNLRRRKIDALKHMLNFNSPITKVVNYDKLWKVLICDKHGLDIISTLFback to top Annotated Terms
The following terms have been associated with this transcript:
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