Neur_chan_LBD domain-containing protein

Overview
NameNeur_chan_LBD domain-containing protein
Smed IDSMED30033894
Length (bp)1935
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Neur_chan_LBD domain-containing protein (SMED30033894) t-SNE clustered cells

Violin plots show distribution of expression levels for Neur_chan_LBD domain-containing protein (SMED30033894) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Neur_chan_LBD domain-containing protein (SMED30033894) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Neur_chan_LBD domain-containing protein (SMED30033894) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033894

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 15

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30033894SMESG000041829.1 SmedASXL_013220SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30033894SMESG000064433.1 SMESG000041829.1 SmedASXL_013222SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30033894SMESG000064433.1 SMESG000041829.1 SmedASXL_013221SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30033894SMESG000041829.1 dd_Smed_v4_19336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30033894SMESG000041829.1 dd_Smed_v4_19336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30033894SMESG000041829.1 dd_Smed_v4_19336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
cilated neuronSMED30033894SMESG000041829.1 dd_Smed_v4_19336_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30033894SMESG000034462.1 SMESG000034379.1 dd_Smed_v4_47882_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30033894SMESG000034462.1 SMESG000034379.1 dd_Smed_v4_47882_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30033894SMESG000034462.1 SMESG000034379.1 dd_Smed_v6_47882_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30033894SMESG000041829.1 dd_Smed_v6_19336_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
neuronSMED30033894SMESG000041829.1 DN298606ncbi_smed_estsPMID:30399335
Ross et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30033894SMESG000041829.1 OX_Smed_1.0.01208ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30033894SMESG000041829.1 DN306571ncbi_smed_estsPMID:25356635
Cowles et al., 2014		whole organism asexual adult fluorescence in situ hybridization evidence
neuronSMED30033894SMESG000041829.1 DN306571ncbi_smed_estsPMID:25356635
Cowles et al., 2014		whole organism asexual adult fluorescence in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 56.6102 bits (135), Expect = 9.043e-8
Identity = 66/285 (23.16%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  + S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEH-RLVSRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 56.225 bits (134), Expect = 1.053e-7
Identity = 67/285 (23.51%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  V S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   34 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEHRLV-SRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 301
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 56.225 bits (134), Expect = 1.561e-7
Identity = 67/285 (23.51%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  V S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:  123 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEHRLV-SRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 390
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 55.8398 bits (133), Expect = 1.662e-7
Identity = 67/285 (23.51%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  V S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEHRLV-SRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB2 (gamma-aminobutyric acid type A receptor beta2 subunit [Source:HGNC Symbol;Acc:HGNC:4082])

HSP 1 Score: 53.5286 bits (127), Expect = 5.770e-7
Identity = 64/285 (22.46%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D + +  +  +E  ++++ ++  +  K V +    G   R +++F  +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:    3 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDD-NAVTGVTKIELPQFSIVDYKLITKKVVFS---TGSYPRLSLSF--KLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGR 270
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: CG8916 (gene:FBgn0030707 transcript:FBtr0301233)

HSP 1 Score: 52.373 bits (124), Expect = 1.097e-6
Identity = 60/269 (22.30%), Postives = 110/269 (40.89%), Query Frame = 1 
Query:  397 YSAEIFLQSKWREPLLDNRSDIKDISLS-----SFWNPKISIENIFMETKSSISHEVSYSGK----AREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNS 1176
            YS + + +  WR+  L  +  IK +SLS       W P    +  F   K S  H ++   K     +   I    R++      +ELQ+FP D Q   + + +   IN+  + E  +    ++ + GM   +++L   +     TV  + +        +       R   YFLI  + +  +  ++         +  T  R+ LC+T++LT  T  +    +LPK+ Y T LD  +L  +  + C+        + + TK+ S  S
Sbjct:   52 YSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRP----DTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDFS-----VLHVAFNLKRHTGYFLI-QVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLL--MSFLYCIATLLEFAGVHYFTKLGSGES 308
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: CG8916 (gene:FBgn0030707 transcript:FBtr0301232)

HSP 1 Score: 51.9878 bits (123), Expect = 1.404e-6
Identity = 60/269 (22.30%), Postives = 110/269 (40.89%), Query Frame = 1 
Query:  397 YSAEIFLQSKWREPLLDNRSDIKDISLS-----SFWNPKISIENIFMETKSSISHEVSYSGK----AREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNS 1176
            YS + + +  WR+  L  +  IK +SLS       W P    +  F   K S  H ++   K     +   I    R++      +ELQ+FP D Q   + + +   IN+  + E  +    ++ + GM   +++L   +     TV  + +        +       R   YFLI  + +  +  ++         +  T  R+ LC+T++LT  T  +    +LPK+ Y T LD  +L  +  + C+        + + TK+ S  S
Sbjct:  154 YSMDCYFRQYWRDKRLSFKGPIKSLSLSIKMLDKIWRP----DTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDFS-----VLHVAFNLKRHTGYFLI-QVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLL--MSFLYCIATLLEFAGVHYFTKLGSGES 410
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrg1 (gamma-aminobutyric acid type A receptor gamma1 subunit [Source:ZFIN;Acc:ZDB-GENE-141215-66])

HSP 1 Score: 55.8398 bits (133), Expect = 1.164e-7
Identity = 60/247 (24.29%), Postives = 105/247 (42.51%), Query Frame = 1 
Query:  367 IFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISI-ENIFMETKSSISHEVSYSGKAREAY----ITEKRRVSGGFREVLELQHFPFDCQDLSITVST-EYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHI----MIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLD 1077
            I  VD +N  Y+ +IF    W +  L   S +K + L+S    KI I +  F  ++ S +H ++   +    +    +    R++      L+L +FP D     +  S+  YP NE++         +  +++  + + W LY+   V  +   +  N    E   MT     SRR  YF I       MI  + ++  + +    P      R  L +TT+LT  T      ++LPK+ Y+T +D
Sbjct:   95 IGPVDPINMEYTIDIFFAQTWYDSRLKFNSSMKLLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYLKLHNFPMDEHSCPLEFSSYGYPKNEIQYRW------QRRSVEVADQRYWRLYQFAFVGLRNSSDVANTQSGEYVVMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPA-----RTSLGITTVLTMTTLSTISRKSLPKVSYVTAMD 330
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrg1 (gamma-aminobutyric acid type A receptor gamma1 subunit [Source:ZFIN;Acc:ZDB-GENE-141215-66])

HSP 1 Score: 55.0694 bits (131), Expect = 1.800e-7
Identity = 60/247 (24.29%), Postives = 105/247 (42.51%), Query Frame = 1 
Query:  367 IFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFME-TKSSISHEVSYSGKAREAY----ITEKRRVSGGFREVLELQHFPFDCQDLSITVST-EYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHI----MIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLD 1077
            I  VD +N  Y+ +IF    W +  L   S +K + L+S    KI I + F   ++ S +H ++   +    +    +    R++      L+L +FP D     +  S+  YP NE++         +  +++  + + W LY+   V  +   +  N    E   MT     SRR  YF I       MI  + ++  + +    P      R  L +TT+LT  T      ++LPK+ Y+T +D
Sbjct:   95 IGPVDPINMEYTIDIFFAQTWYDSRLKFNSSMKLLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYLKLHNFPMDEHSCPLEFSSYGYPKNEIQYRW------QRRSVEVADQRYWRLYQFAFVGLRNSSDVANTQSGEYVVMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPA-----RTSLGITTVLTMTTLSTISRKSLPKVSYVTAMD 330
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrb1 (gamma-aminobutyric acid type A receptor beta1 subunit [Source:ZFIN;Acc:ZDB-GENE-090313-230])

HSP 1 Score: 54.299 bits (129), Expect = 3.246e-7
Identity = 65/285 (22.81%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++        S +  +D +E  ++++ ++  +  K V      G   R +++F  +  R   YF++   M S++  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   75 IDISSIDMVSEVNMDYTITMYFQQSWRDKRLSYTGIPLNLTLDNR--VAD----QLWVP----DTYFINDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--QGGSSVTGVDNIELPQFSIIDYKTLSKKVVFA---TGSYPRLSLSFKLK--RNIGYFILQTYMPSTLITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGR 341
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrb4 (gamma-aminobutyric acid type A receptor beta4 subunit [Source:ZFIN;Acc:ZDB-GENE-070424-211])

HSP 1 Score: 53.5286 bits (127), Expect = 6.046e-7
Identity = 61/279 (21.86%), Postives = 123/279 (44.09%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWREPLLDNRSDIKDISLSS-----FWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D+++E    Y+  ++ Q  WR+  L       +++L +      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  +++       D    N + G++  E   +  VE+   +       G   R +++F  R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   68 INIASIDSISEVNMDYTITMYFQQSWRDKRLAYAEMALNLTLDNRVADQLWLP----DTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIVFFWQGGD----NAVTGVDKLELPQFSIVELRLVSREVRFTTGSYPRLSLSF--RIKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGVTTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYVFFGR 335
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrb2a (gamma-aminobutyric acid type A receptor beta2 subunit a [Source:ZFIN;Acc:ZDB-GENE-030131-8196])

HSP 1 Score: 51.9878 bits (123), Expect = 1.013e-6
Identity = 62/272 (22.79%), Postives = 119/272 (43.75%), Query Frame = 1 
Query:  397 YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVE--SKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D      + G+E  E   +  V+ +  SK V+      PR    ++ + +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   14 YTLTMYFQQAWRDKRLSYSEIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD----GAVSGVERIELPQFSIVDYKLISKNVVFSTGSYPR----LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 266
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000020814.1 (gamma-aminobutyric acid type A receptor theta subunit [Source:NCBI gene;Acc:100496398])

HSP 1 Score: 60.077 bits (144), Expect = 6.415e-9
Identity = 65/280 (23.21%), Postives = 126/280 (45.00%), Query Frame = 1 
Query:  367 IFKVDTVNEFYSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I ++  VN  Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y I+++K      + + +  +  +E  ++ + E   + SK V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   60 IDQISEVNMDYTITMYFQQSWRDKRLAYTALPLNLTLDNR--VAD----QLWLP----DTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDQQNCTLEIESYGYTIDDIKFFWQGGEEAAVTGVSALELPQFTIIE-TRLVSKNVVFTTGSYPR----LSLSFRIKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGVTTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYVFFGR 323
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000020832.1 (gamma-aminobutyric acid type A receptor theta subunit [Source:NCBI gene;Acc:100496398])

HSP 1 Score: 60.077 bits (144), Expect = 6.573e-9
Identity = 65/280 (23.21%), Postives = 126/280 (45.00%), Query Frame = 1 
Query:  367 IFKVDTVNEFYSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I ++  VN  Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y I+++K      + + +  +  +E  ++ + E   + SK V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   77 IDQISEVNMDYTITMYFQQSWRDKRLAYTALPLNLTLDNR--VAD----QLWLP----DTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDQQNCTLEIESYGYTIDDIKFFWQGGEEAAVTGVSALELPQFTIIE-TRLVSKNVVFTTGSYPR----LSLSFRIKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGVTTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYVFFGR 340
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000004017.1 (gamma-aminobutyric acid (GABA) A receptor, beta 1 [Source:NCBI gene;Acc:100489344])

HSP 1 Score: 58.5362 bits (140), Expect = 2.106e-8
Identity = 69/289 (23.88%), Postives = 130/289 (44.98%), Query Frame = 1 
Query:  340 VYLRCVFIKIFKVDTVNEFYSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            V +R     I  V  VN  Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  +++K      D   +  ++ +E  ++++ ++  V S+ VI      PR    ++ + R  R   YF++   M S++  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  K
Sbjct:   63 VGMRIDVASIDMVSEVNMDYTLTMYFQQSWRDKRLSYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKRSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIKFYWNGGD-KAITGVEKIELPQFSIIDYKMV-SRNVIFSTGAYPR----LSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAA-RVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGK 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: dusp5 (dual specificity phosphatase 5 [Source:Xenbase;Acc:XB-GENE-957572])

HSP 1 Score: 55.8398 bits (133), Expect = 1.708e-7
Identity = 65/285 (22.81%), Postives = 131/285 (45.96%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D + +  ++ +E  ++++ +H ++ SK V+      PR    ++ + +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYTGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWLGGD-NAVTGVERIELPQFSIMDH-KLVSKNVVFATGSYPR----LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Match: gabrb2 (gamma-aminobutyric acid (GABA) A receptor, beta 2 [Source:NCBI gene;Acc:100125027])

HSP 1 Score: 52.373 bits (124), Expect = 1.717e-6
Identity = 67/287 (23.34%), Postives = 127/287 (44.25%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVE--SKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  +++       +    N + G+E  E   +  ++    S+ V+   + G   R +++F  R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   49 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSVIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIGFYWRGGN----NAVTGVERLELPQFSIIDYNLLSRNVV--FSTGSYPRLSLSFKLR--RNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGR 316
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621])

HSP 1 Score: 56.6102 bits (135), Expect = 7.261e-8
Identity = 66/285 (23.16%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  + S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEH-RLVSRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621])

HSP 1 Score: 56.225 bits (134), Expect = 9.777e-8
Identity = 67/285 (23.51%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  V S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   89 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEHRLV-SRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 356
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621])

HSP 1 Score: 55.8398 bits (133), Expect = 1.065e-7
Identity = 67/285 (23.51%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  V S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEHRLV-SRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Glra4 (glycine receptor, alpha 4 subunit [Source:MGI Symbol;Acc:MGI:95750])

HSP 1 Score: 54.299 bits (129), Expect = 3.172e-7
Identity = 62/266 (23.31%), Postives = 110/266 (41.35%), Query Frame = 1 
Query:  397 YSAEIFLQSKWREPLL------DNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTC-----RASRRFKYFLIN----HIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHAS 1134
            Y   +FL+ +W +P L      D+  D+    L S W P +     F   K +  HEV+   K     +   +    R++      ++L++FP D Q  ++ + S  Y +N++ M E   D   +   +G+   ++ L +           D     +   T  FTC        R+  Y+LI      ++I  + ++  + +   AP      R+GL +TT+LT  T       +LPK+ Y+  +D      I M +CL    A+
Sbjct:   91 YRVNVFLRQQWNDPRLAYREYPDDSLDLDPSMLDSIWKPDL----FFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDL-MFEWLEDAPAVQVAEGLTLPQFILRDE---------KDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA-----RVGLGITTVLTMTTQSSGSRASLPKVSYVKAID------IWMAVCLLFVFAA 331
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747])

HSP 1 Score: 53.1434 bits (126), Expect = 5.726e-7
Identity = 62/260 (23.85%), Postives = 110/260 (42.31%), Query Frame = 1 
Query:  397 YSAEIFLQSKWREPLL------DNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGK----AREAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTC-----RASRRFKYFLIN----HIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCL 1116
            Y   IFL+ +W +P L      D+  D+    L S W P +     F   K +  HE++   K    +R   +    R++      ++L++FP D Q   + + S  Y +N++ + E   +   +   DG+   ++ L E  ++   T         +   T  FTC        R+  Y+LI      ++I  + ++  + +   AP      R+GL +TT+LT  T       +LPK+ Y+  +D      I M +CL
Sbjct:    3 YRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDL----FFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDL-IFEW-QEQGAVQVADGLTLPQFILKEEKDLRYCT---------KHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPA-----RVGLGITTVLTMTTQSSGSRASLPKVSYVKAID------IWMAVCL 236
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P19019|GBRB3_CHICK (Gamma-aminobutyric acid receptor subunit beta-3 OS=Gallus gallus OX=9031 GN=GABRB3 PE=2 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 1.421e-7
Identity = 71/287 (24.74%), Postives = 126/287 (43.90%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVE--SKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D    N + G+E  E   +  VE    SK V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  K
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYAGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD----NAVTGVERIELPQFSIVEYRLVSKNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGK 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P28472|GBRB3_HUMAN (Gamma-aminobutyric acid receptor subunit beta-3 OS=Homo sapiens OX=9606 GN=GABRB3 PE=1 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 4.343e-7
Identity = 66/285 (23.16%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  + S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEH-RLVSRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P63079|GBRB3_RAT (Gamma-aminobutyric acid receptor subunit beta-3 OS=Rattus norvegicus OX=10116 GN=Gabrb3 PE=1 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 5.079e-7
Identity = 66/285 (23.16%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  + S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEH-RLVSRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P63080|GBRB3_MOUSE (Gamma-aminobutyric acid receptor subunit beta-3 OS=Mus musculus OX=10090 GN=Gabrb3 PE=1 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 5.079e-7
Identity = 66/285 (23.16%), Postives = 129/285 (45.26%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D   +  ++ +E  ++++ EH  + S+ V+      PR    ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD-KAVTGVERIELPQFSIVEH-RLVSRNVVFATGAYPR----LSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P24045|GBRB4_CHICK (Gamma-aminobutyric acid receptor subunit beta-4 OS=Gallus gallus OX=9031 GN=GABRB4 PE=2 SV=1)

HSP 1 Score: 54.6842 bits (130), Expect = 2.055e-6
Identity = 64/280 (22.86%), Postives = 123/280 (43.93%), Query Frame = 1 
Query:  367 IFKVDTVNEFYSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I ++  VN  Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y ++++      +D    + + GME  E  L +   +E + V  +          ++ + R  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   71 IDQISEVNMDYTITMYFQQSWRDKRLAYNDLPLNLTLDNR--VAD----QLWLP----DTYFLNDKKSFLHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDQQNCTLEIESYGYTVDDIVFFWQGND----SAVTGMEVLE--LPQFTIIEQRLVSREVVFTTGSYLRLSLSFRIKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGVTTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYIFFGR 333
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A4E0RSR9 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_005714 PE=4 SV=1)

HSP 1 Score: 242.662 bits (618), Expect = 4.686e-70
Identity = 147/367 (40.05%), Postives = 213/367 (58.04%), Query Frame = 1 
Query:  355 VFIKIFKVDTVNEFYSAEIFLQSKWREPLLD-------------NRSDIKD---------------ISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQ--TMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHA-STSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEK 1362
            +F+KI +VDTVNE Y A+IFLQ++WREPLLD              +S +++               +    FWNP++ ++N   E    +SHEV +     EAY+ EKRR+ G F E LEL+HFPFD QDLS+TV+ +  ++EV ++  P ++S+++     +SQEW ++ HV+VE   +    + G  +R+   + FT R++RR  YF++N ++IS +  LL+F  FS+    N   RL   +  LLT+VTFK A SQNLPKI YLTYLDK +L N  M++ L +WH  + SL        DN           EKY++ +L+  Y L  +  GLT+Y DAG RRR M  KDVEF ++  +IE EK
Sbjct:    3 IFVKIGQVDTVNERYQADIFLQARWREPLLDATWKSERAQKNWRGKSGVENPIQDLVPKRHLHTLGLQDDEFWNPRLLLDNAQGEPIEIVSHEVEFVEPTFEAYLVEKRRIKGVFHETLELKHFPFDVQDLSVTVTCDRSVDEVLLVPSPTEVSQVDRRGAADSQEWKIFHHVDVERMEIQTAYSPGTSKRRHPGLVFTSRSARRSGYFMVNMVLISCVLCLLSFCIFSVPVDGN---RLQQALLLLLTTVTFKFAASQNLPKISYLTYLDKVVLANFFMLVILTVWHTIARSLSASYPKLLDN-----------EKYVVYTLLSSYCLGAVIFGLTVYLDAGSRRRLMQRKDVEFGQLKTRIEREK 355
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A3R7CFX9 (Neuronal acetylcholine receptor subunit alpha-7 OS=Clonorchis sinensis OX=79923 GN=CHRNA7 PE=4 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 6.206e-70
Identity = 144/371 (38.81%), Postives = 214/371 (57.68%), Query Frame = 1 
Query:  340 VYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDN-------RSDIKDISL---------------------SSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIG--PRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEK 1362
            V L  +F+KI +VDTVNE Y A+IFLQ++WREPLLD        R++ +   +                       FWNP++ ++N   E    +SHEV +     EAY+ EKRR+ G F E LEL+HFPFDCQDLS+TV+ +  + EV+++  P ++S+++     +SQEW ++ HV++ S  +    + G   R    + FT R++RR  YF++N  +IS +  LL+F+ FS+    N   RL L +  LLT+VTFK A SQNLPKI YLTYLDK +L N  M++ L +WH      F               ++  E+Y++ +L+  Y L  +  GLT+Y DAG RRR M +KD++F++  ++IE EK
Sbjct:   39 VELMLIFVKIGQVDTVNERYQADIFLQARWREPLLDATWNTSRPRNNFRTFKMVENPVMELAPKRHLHTLKLQDDEFWNPRLLLDNAQGEPIEIVSHEVEFVEPDFEAYLVEKRRIKGVFHETLELKHFPFDCQDLSVTVTCDRTVEEVELVPSPTEVSQVDRRCAADSQEWKIFHHVDIASMEIQTAYSPGTCKRRHPGLVFTSRSARRAGYFMVNMALISCVLSLLSFSVFSVPVDGN---RLQLSLLLLLTTVTFKFAASQNLPKISYLTYLDKMVLANFFMLVILTVWHTIARSVF----------AKYPGLKDKEQYVVYTLLSAYCLGAVVFGLTVYLDAGSRRRLMKSKDMDFTQHKQRIELEK 396
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A075A8W6 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_08254 PE=3 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 7.710e-68
Identity = 147/379 (38.79%), Postives = 218/379 (57.52%), Query Frame = 1 
Query:  316 VNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDN-------RSDIKDISL---------------------SSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIG--PRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEK 1362
            V  P AR V L  +F+KI +VDTVNE Y A+IFLQ++WREPLLD        R++ +  ++                       FWNP++ ++N   E    +SHEV +     EAY+ EKRR+ G F E LEL+HFPFDCQDLS+TV+ +  + EV+++  P ++S+++     +SQEW ++ HV++ S  +    + G   R    + FT R++RR  YF++N  +IS +  LL+F+ FS+    N   RL L +  LLT+VTFK A SQNLPKI YLTYLDK +L N  M++ L +WH      F               ++  E+Y++ +L+  Y L  +  GLT+Y DAG RRR M +KD++F++  ++IE  K
Sbjct:  232 VRHPPAR-VELMLIFVKIGQVDTVNERYQADIFLQARWREPLLDATWNTSRPRNNFRTFNMVENPVMELAPKRHLHTLKLQDDEFWNPRLLLDNAQGEPIEIVSHEVEFVEPDFEAYLVEKRRIKGIFHETLELKHFPFDCQDLSVTVTCDRTVEEVELVPSPTEVSQVDRRCAADSQEWKIFHHVDIASMEIQTAYSPGTCKRRHPGLVFTSRSARRAGYFMVNMALISCVLSLLSFSVFSVPVDGN---RLQLSLLLLLTTVTFKFAASQNLPKISYLTYLDKMVLANFFMLVILTVWHTIARSVF----------AKYPGLKDKEQYVVYTLLSAYCLGAVVFGLTVYLDAGSRRRLMKSKDMDFTQHKQRIELAK 596
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: R7VF52 (Neur_chan_LBD domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_228357 PE=3 SV=1)

HSP 1 Score: 233.032 bits (593), Expect = 1.527e-66
Identity = 131/345 (37.97%), Postives = 203/345 (58.84%), Query Frame = 1 
Query:  337 LVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRS--DIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTI------YFDAGKRRREMIAKDVEFSEMIKK 1347
             V LR VF+KI ++DT+ E YSA+ F+Q+KWREP LD ++  ++K I L  FWNP + IEN+  ETK +     S + +A EA++ E+RRV G F E LEL  FP D QDL++T+++E P  E+ ++   +++S +N    ++ QEW L+EH+EV  K +  + +   R    ++ TCRA+RR  YF  N  ++      L+F +F+++P+     RL L  T LLTS+TFK  ++Q+LPKI YLTY+DK +L ++V++  +C+WHA  ++F                  GI   +     VF   +++ +G  +      YFDA KRRR M  KD E+ + + K
Sbjct:   33 FVELRVVFLKIGEIDTLKEQYSADTFIQAKWREPALDGKTTEELKRIDLDRFWNPLLFIENVLSETKEATWLTASTNSRA-EAFVLERRRVRGVFMENLELNDFPLDVQDLTVTITSERPDTEIDIIPDENEMSGINVQTFVDQQEWRLHEHIEVSKKVMTQEYSSSNRCHPALSVTCRAARRPGYFYWNVFLVMFFISALSFATFAVSPELPQ-NRLQLSFTLLLTSITFKFVINQSLPKISYLTYMDKYVLLSLVILCMVCVWHAVVTVF---------------VHHGINFLMTLERDVFIAFSVIYIGFHVVFIFWLYFDACKRRRLMKHKDKEYLDFLAK 360
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A5K4FCR6 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 240.35 bits (612), Expect = 2.121e-66
Identity = 152/386 (39.38%), Postives = 220/386 (56.99%), Query Frame = 1 
Query:  301 NNSKSVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLD----------------------------NRSDIKDISLSS--FWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVIN--DCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEK 1362
            N  K +N   AR V L  +F+K+ +VDTVNE Y A+IFLQ++WREPLLD                            ++  +  + L    FWNP++ I+N   E    ISHEV +     EAY+ EKRR+ G F E LEL+HFPFDCQDLS+T++ +   +EV+++  P ++S+++     +SQEW ++ HV+++S  +      +   R    + FT R++RR  YFL+N I+IS +  LL+F++FS+    N   RL L +  LLT+VTFK A SQNLPKI YLTYLDK +L N  M++ L +WHA       +K                E Y++ SL+  Y +  +  GLT+Y DAG RRR M  KD+EF++  ++IE EK
Sbjct:  264 NIGKPMNMSKAR-VELVLIFVKVGQVDTVNERYQADIFLQARWREPLLDAMWNKSSLKSKSSWQTNPSIENPFTDLTSKRQLNTLKLQDDEFWNPRLLIDNAEGEPIEIISHEVEFIEPDFEAYLVEKRRIKGIFHETLELRHFPFDCQDLSVTITCDRTTDEVELVASPTEVSQVDVRCAADSQEWKIFHHVDIKSIEIQTGYSPSTSKRHHPGLVFTSRSARRSGYFLVNMILISCVLCLLSFSAFSVPANEN---RLQLSLLLLLTTVTFKFAASQNLPKISYLTYLDKVVLVNFFMLVILTVWHAIARAVSASK----------PKFLEYEHYVMYSLLSCYCIGSVLFGLTVYLDAGSRRRLMKRKDIEFNQYKQQIEAEK 635
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: gabrb1 (gamma-aminobutyric acid type A receptor beta1 subunit [Source:ZFIN;Acc:ZDB-GENE-090313-230])

HSP 1 Score: 54.6842 bits (130), Expect = 2.157e-7
Identity = 65/285 (22.81%), Postives = 130/285 (45.61%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      + S +  +D +E  ++++ ++  +  K V      G   R +++F  +  R   YF++   M S++  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   53 IDISSIDMVSEVNMDYTITMYFQQSWRDKRLSYTGIPLNLTLDNR--VAD----QLWVP----DTYFINDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--QEGSSVTGVDNIELPQFSIIDYKTLSKKVVFA---TGSYPRLSLSFKLK--RNIGYFILQTYMPSNLITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGR 319
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: gabrb2a (gamma-aminobutyric acid type A receptor beta2 subunit [Source:NCBI gene;Acc:103045154])

HSP 1 Score: 53.5286 bits (127), Expect = 5.369e-7
Identity = 67/287 (23.34%), Postives = 126/287 (43.90%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVE--SKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D      + G+E  E   +  V+ +  SK V+      PR    ++ + +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   65 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD----GAVSGVERIELPQFSIVDYKLISKNVVFSTGSYPR----LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: gabrb2a (gamma-aminobutyric acid type A receptor beta2 subunit [Source:NCBI gene;Acc:103045154])

HSP 1 Score: 53.1434 bits (126), Expect = 6.146e-7
Identity = 67/287 (23.34%), Postives = 126/287 (43.90%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVE--SKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D      + G+E  E   +  V+ +  SK V+      PR    ++ + +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   65 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD----GAVSGVERIELPQFSIVDYKLISKNVVFSTGSYPR----LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 332
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: GABRB2 (gamma-aminobutyric acid receptor subunit beta-2 [Source:NCBI gene;Acc:103038806])

HSP 1 Score: 52.373 bits (124), Expect = 1.099e-6
Identity = 66/287 (23.00%), Postives = 127/287 (44.25%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVE--SKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      +    + + G+E  E   +  V+ +  SK V+      PR    ++ + +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   68 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGN----HAVTGVERIELPQFSIVDYKLISKNVVFSTGAYPR----LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYALVNYIFFGR 335
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: gabrb3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:NCBI gene;Acc:103041149])

HSP 1 Score: 52.373 bits (124), Expect = 1.193e-6
Identity = 64/279 (22.94%), Postives = 122/279 (43.73%), Query Frame = 1 
Query:  376 VDTVNEFYSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVE--SKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            V  VN  Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      D    N + G+   E   +  V+ +  S+ V+      PR    ++ + +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   96 VSEVNMDYTLTMYFQQYWRDKRLAYAGIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWKGGD----NAVTGVSRIELPQFSIVDYKLVSRNVVFSTGAYPR----LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 355
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1])

HSP 1 Score: 48.521 bits (114), Expect = 2.850e-6
Identity = 60/266 (22.56%), Postives = 112/266 (42.11%), Query Frame = 1 
Query:  397 YSAEIFLQSKWREPLL------DNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTC-----RASRRFKYFLIN----HIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHAS 1134
            Y   IFL+ +W +P L      D+  D+    L S W P +     F   K +  HEV+   K     ++  +    R++      ++L++FP D Q  ++ + S  Y +N++ + E   +   +   +G+   ++ L +  ++   T         +   T  FTC        R+  Y+LI      ++I  + ++  + +   AP      R+ L +TT+LT  T       +LPK+ Y+  +D      I M +CL    A+
Sbjct:   27 YRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDL----FFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDL-IFEWKQE-GAVQVAEGLTLPQFVLKDEKDLVYCT---------KHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA-----RVALGITTVLTMTTQSSGSRASLPKVSYVKAID------IWMAVCLLFVFAA 266
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO32790 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU26])

HSP 1 Score: 102.834 bits (255), Expect = 1.404e-23
Identity = 75/266 (28.20%), Postives = 136/266 (51.13%), Query Frame = 1 
Query:  340 VYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGM---ESQEWNLYEHVEVESKTVINDCNIGPRERQTMTF--TCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCI 1122
            V +RC    +  +D + + ++ E+++ + WREP L  + + +++   + W+PKIS  N  +  +      + Y   +      E  ++ G F+E   L+ FP D Q+LSI +S+++    V   +   D++K + +        ++W LY HV  ++ T   +  +GP +R    +  T    RR  ++  N  ++ S+   L+F SF+I PQ  T  RL + +  LL SV +K   S +LP+  YLT+LDK  LGN++ I  + +
Sbjct:   18 VLIRCGISFLGDIDVIRQQFTCELWMTASWREPKLAGKKN-EEVKWDNEWSPKISFSNSLLLDRVYKGRRLYYEENSTVPLAQEVYKIRGTFKEQFSLEQFPVDLQELSIIISSDWSDRTVTFEK---DMAKPDYLRQQTFSSPRDWVLYPHVHTDTATQEGE-GLGPNDRSYPVYIITAHVRRRAVHYFWNTAVVMSVLTALSFASFAIPPQ-QTADRLTVTLLLLLISVAYKFVTSLHLPRTSYLTFLDKYQLGNLLFISFIAV 277
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO35410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK4])

HSP 1 Score: 59.6918 bits (143), Expect = 1.021e-9
Identity = 70/278 (25.18%), Postives = 133/278 (47.84%), Query Frame = 1 
Query:  313 SVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLL--DNRSDIKDISLSSFWNPKISIENI-FMETKSSISHEVSYSGKAREAYITEKRRVSGGFREV---------LELQHFPFDCQDLSITVSTEYPINEVKMLECPHD-LSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMI 1107
            S  +PV  +VY+      I+ +  +N  ++ +I+L+  WR+  L  + ++    ++LSS  N +I + +  F+ TK +  H+V+      + Y+ + +     F  +         L+L+ FP D Q  S+++ + Y      +L   ++ L   + I   +  E   +E + V     +N  NIG        F  R  RR  YFLI+  + S++  ++++ SF I P+T    R+ L +TT+LT  T   +   NLPK+ Y+  +D  +L  ++ +
Sbjct:   41 SKGEPV--VVYVDMYVSNIWAMQEMNMDFTIDIYLRQYWRDERLQFETQTPGAMLTLSSDINKQIWVPSTYFLATKKAYFHDVT-----TDNYLLQVKPDGSLFYSIRLTITTSCRLDLRDFPHDTQSCSLSLES-YGYQSTDVLYVWNERLDNTSAIYIHDDLELPQFEVLGVSRSAKMNKYNIGNHSSLVANF--RMKRRIGYFLIDTYIPSTIIVIISWISFWIDPETAP-ARVALGITTVLTMTTLISSARANLPKVSYVKAIDWYLLLCLIFV 307
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO26859 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAV8])

HSP 1 Score: 52.7582 bits (125), Expect = 5.568e-8
Identity = 42/122 (34.43%), Postives = 67/122 (54.92%), Query Frame = 1 
Query:  763 QEWNLYEHVEVESKTVINDCNIGPRERQTMTF--TCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCI 1122
            ++W LY HV  ++ T   +  +GP +R    +  T    RR  ++  N  ++ S+   L+F SF+I PQ  T  RL + +  LL SV +K   S +LP+  YLT+LDK  LGN++ I  + +
Sbjct:   16 RDWVLYPHVHTDTATQEGE-GLGPNDRSYPVYIITAHVRRRAVHYFWNTAVVMSVLTALSFASFAIPPQ-QTADRLTVTLLLLLISVAYKFVTSLHLPRTSYLTFLDKYQLGNLLFISFIAV 135
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO43147 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZH2])

HSP 1 Score: 51.2174 bits (121), Expect = 4.837e-7
Identity = 61/260 (23.46%), Postives = 112/260 (43.08%), Query Frame = 1 
Query:  364 KIFKVDTVNEF---YSAEIFLQSKWREP-LLDNRSD---IKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAY----ITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMI 1107
            K+  +  +NE    +S +IF +  W EP    N S+   + + +   FW P    +  F+  K S  H+V+        Y    +    R++   +  + LQ FP D Q   + + S  Y   ++K    P     +  I    +Q    +  VE  ++ +      G   +   TF+ +  RR +YF I  +  + +  +L++  F I P      R+ L +TT+L+++     V+  +PK+ Y+  +D  +LGN   I
Sbjct:   35 KVVSLGGINEASMEFSMDIFFRQWWHEPRFTHNYSEPFTMAEDAGKLFWIP----DTYFINAKKSNFHKVTKENARIIIYPSGNVYYSVRLTLTLQCNMNLQLFPMDVQACPLFIESYAYTSEDIKYKWTPRGTKGIEIISNETAQ----FVLVEARTEQIATAKISGHFSQLVATFSLK--RRLEYFAITVVTPAMILVVLSWCCFWIVPDA-IPARISLSVTTILSTLLLSGTVNAQMPKVSYMKAIDVFVLGNFAFI 283
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: gabrb2a (gamma-aminobutyric acid type A receptor beta2 subunit [Source:NCBI gene;Acc:101165154])

HSP 1 Score: 55.0694 bits (131), Expect = 1.378e-7
Identity = 71/324 (21.91%), Postives = 145/324 (44.75%), Query Frame = 1 
Query:  271 ILICDTNKMENNSKSVNKPVARL-----VYLRCVF----------IKIFKVDTVNEF---YSAEIFLQSKWREPLLDNRSDIKDISLSS-----FWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I +CD  K  +N   V + V RL     + LR  F          I I  +D V+E    Y+  ++ Q  WR+  L       +++L +      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++      +   ++ +D +E  ++++ ++ ++ SK V+      PR    ++ + +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   18 ISLCDDIKDPSNMPLVKETVDRLMKGYDIRLRPDFGGAPVAVGMNIDISSIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIAYNLTLDNRVADQLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGE-GAVSGVDRIELPQFSIVDY-KLISKNVVFSTGSYPR----LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGQ 330
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: gabrb1 (gamma-aminobutyric acid type A receptor beta1 subunit [Source:NCBI gene;Acc:101154825])

HSP 1 Score: 54.299 bits (129), Expect = 2.433e-7
Identity = 63/286 (22.03%), Postives = 131/286 (45.80%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKML-ECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++   +   +   +  ++ +E  ++++ ++  + +K V      G   R +++F  +  R   YF++   M S++  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   64 IDIASIDMVSEVNMDYTITMYFQQSWRDKRLSYTGIPLNLTLDNR--VAD----QLWVP----DTYFINDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWQGGSNAGSVTGVENIELPQFSIIDYQTLSTKAVFA---TGSYPRLSLSFKLK--RNIGYFILQTYMPSTLITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGR 333
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: GABRB2 (gamma-aminobutyric acid receptor subunit beta-2 [Source:NCBI gene;Acc:101167169])

HSP 1 Score: 54.299 bits (129), Expect = 2.840e-7
Identity = 64/285 (22.46%), Postives = 130/285 (45.61%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++       +  +  ++ +E  ++++ +H ++ SK V+      PR    ++ + +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   62 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFY-WRGGVGAVTGVERIELPQFSIVDH-KLISKNVVFSTGAYPR----LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYIFFGR 329
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: GABRB2 (gamma-aminobutyric acid receptor subunit beta-2 [Source:NCBI gene;Acc:101167169])

HSP 1 Score: 54.299 bits (129), Expect = 3.017e-7
Identity = 64/285 (22.46%), Postives = 130/285 (45.61%), Query Frame = 1 
Query:  361 IKIFKVDTVNEF---YSAEIFLQSKWRE--------PL---LDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKA----REAYITEKRRVSGGFREVLELQHFPFDCQDLSITV-STEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTK 1158
            I I  +D V+E    Y+  ++ Q  WR+        PL   LDNR  + D      W P    +  F+  K S  H V+   +      +  +    R++     +++L+ +P D Q+ ++ + S  Y  ++++       +  +  ++ +E  ++++ +H ++ SK V+      PR    ++ + +  R   YF++   M S +  +L++ SF I    +   R+ L +TT+LT  T    + + LPKIPY+  +D  ++G  V +    + +A  +  F  +
Sbjct:   67 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNR--VAD----QLWVP----DTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFY-WRGGVGAVTGVERIELPQFSIVDH-KLISKNVVFSTGAYPR----LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA-RVALGITTVLTMTTINTHLRETLPKIPYVKAIDVYLMGCFVFVFLALLEYAFVNYIFFGR 334
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: gabrg1 (gamma-aminobutyric acid type A receptor gamma1 subunit [Source:NCBI gene;Acc:101155813])

HSP 1 Score: 53.1434 bits (126), Expect = 6.766e-7
Identity = 59/247 (23.89%), Postives = 103/247 (41.70%), Query Frame = 1 
Query:  367 IFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISI-ENIFMETKSSISHEVSYSGKAREAY----ITEKRRVSGGFREVLELQHFPFDCQDLSITVST-EYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHI----MIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLD 1077
            I  VD +N  Y+ +IF    W +  L   S +K + L+S    KI I +  F  ++ S +H ++   +    +    +    R++      L+L +FP D     +  S+  YP NE+          +   ++  + + W LY+   V  +   +  +    E   MT     SRR  YF I       MI  + ++  + +    P      R  L +TT+LT  T      ++LPK+ Y+T +D
Sbjct:   88 IGPVDPINMEYTIDIFFAQTWYDSRLKFNSSMKLLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYLKLHNFPMDEHSCPLEFSSYGYPRNEIMYRW------QRRAVEVADQRYWRLYQFAFVGMRNTSDVAHTQSGEYVIMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPA-----RTSLGITTVLTMTTLSTISRKSLPKVSYITAMD 323
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000041829.1 (SMESG000041829.1)

HSP 1 Score: 719.153 bits (1855), Expect = 0.000e+0
Identity = 362/362 (100.00%), Postives = 362/362 (100.00%), Query Frame = 1 
Query:  295 MENNSKSVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEKLFCDVC 1380
            MENNSKSVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMISSMFFLLTFTSFSIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEKLFCDVC
Sbjct:    1 MENNSKSVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMISSMFFLLTFTSFSIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEKLFCDVC 362
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000041818.1 (SMESG000041818.1)

HSP 1 Score: 543.888 bits (1400), Expect = 0.000e+0
Identity = 274/362 (75.69%), Postives = 311/362 (85.91%), Query Frame = 1 
Query:  295 MENNSKSVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEKLFCDVC 1380
            ME  SKS +K   +LVYLRCVFIKI+KVDT+NEFYS +IFLQ+KWREPLLD+R+D+KDI+LS+FWNPK+ IEN+F E+KSS+ HEVS+S K  EAYITEKRR+   FRE LELQHFPFDCQDLSI V+TEY INEVK++E PHDLSKLNTIDGMESQEWNLYEHVEVESKT+IN+CNIGPRERQ MTFTCRASR+FKYFLINHIMISSMFFLLTFTSFSI P  NT++RLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDK ILGNI+MIM LCIWHA TSLFF  K  + + T T + I   E+ +IP L+ FY +AIL  GL IYFDAGKRRREM+ KD EF+E + KIE EKLFC+VC
Sbjct:    1 MEVESKSNHKQSKKLVYLRCVFIKIYKVDTINEFYSGDIFLQAKWREPLLDDRTDMKDINLSTFWNPKLVIENMFQESKSSVVHEVSFSEKRHEAYITEKRRIKACFRETLELQHFPFDCQDLSIPVATEYSINEVKLVELPHDLSKLNTIDGMESQEWNLYEHVEVESKTIINECNIGPRERQIMTFTCRASRKFKYFLINHIMISSMFFLLTFTSFSITPARNTFFRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNILMIMSLCIWHACTSLFF--KFTTTDDTTTASVISTAEQKIIPCLLGFYSIAILVSGLAIYFDAGKRRREMLLKDAEFAEALAKIEAEKLFCEVC 360
[Close]
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000041796.1 (SMESG000041796.1)

HSP 1 Score: 493.812 bits (1270), Expect = 7.539e-171
Identity = 253/362 (69.89%), Postives = 292/362 (80.66%), Query Frame = 1 
Query:  295 MENNSKSVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYS-GKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEKLFCDV 1377
            MENNSKS      R VYLRCVFIKI+KVDTVNEFYS EIFL +KWREPLLDN+SD+KDISLS+FWNPK+SIENIF  TKS+ S EVS+  G  + A++ EK R+   FRE LELQHFPFDCQDLSI+V TEY I E++M E P+D+SKLNT+DG+ESQEWNLYEHVEVE+K VINDCN GP+ERQ MTFTCRA+RRFKYFLINH MISSMFFLLTF+SFSI   TNTY RL LCMTTLLTSVTFKVAVSQNLPKIPYLTYLDK ILGNI+MIM LCIWHA TS +F+    S N+T+  +++  IE  LIP+L+ FY +AIL     IY+DAG RRREM  KD EF  +  K E E+LFC++
Sbjct:   54 MENNSKSNQIKTKRKVYLRCVFIKIYKVDTVNEFYSGEIFLHAKWREPLLDNKSDLKDISLSTFWNPKLSIENIFQITKSTTSLEVSFDEGNNKRAFVVEKTRIKAAFRETLELQHFPFDCQDLSISVGTEYSIEELEMAENPNDISKLNTLDGIESQEWNLYEHVEVENKIVINDCNFGPKERQIMTFTCRATRRFKYFLINHFMISSMFFLLTFSSFSII-STNTYGRLALCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNILMIMLLCIWHAVTSFWFIDP--STNTTVAMSSLTNIENILIPTLLGFYLIAILTFAFIIYYDAGSRRREMTEKDNEFKSLSIKKENERLFCEL 412
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BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000064433.1 (SMESG000064433.1)

HSP 1 Score: 487.263 bits (1253), Expect = 4.439e-169
Identity = 249/347 (71.76%), Postives = 287/347 (82.71%), Query Frame = 1 
Query:  340 VYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEKLFCDVC 1380
            VYLRCVF+KI+KVDTVNEFYS EIFLQSKWREPLLD++ ++KD++L SFWNPK+ IENIF E KSS+S EV+++ K  EA+I EKRRV   FRE LELQHFPFDCQDLS++V+TEY I+EV ++E P+D+SKLNT+DG+ESQEWNLYEHVEVE+KT+INDCNIGP+ERQ MTFTCRASRRFKYFLINH +ISSMFFLLTFTSFSI P + TY RL LCMTTLLTSVTFKVAVSQNLPKIPYLTYLDK ILGNI+ IM LC WHASTS FF     S  S   T  ++ +E Y+I   +  YGL IL  GL IYFDAG RRREM  KD EF  +++KIE EKLFCDVC
Sbjct:   16 VYLRCVFVKIYKVDTVNEFYSGEIFLQSKWREPLLDHKPNLKDVNLFSFWNPKLIIENIFTENKSSVSLEVTFTEKY-EAFIIEKRRVKASFRETLELQHFPFDCQDLSVSVATEYSIDEVDLVETPNDVSKLNTLDGIESQEWNLYEHVEVEAKTMINDCNIGPKERQIMTFTCRASRRFKYFLINHFLISSMFFLLTFTSFSIPP-SPTYGRLALCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNILFIMLLCFWHASTSFFFNDTTIS--SATATANVKQVETYIISCFLGVYGLVILIFGLVIYFDAGSRRREMSDKDREFKRLLEKIENEKLFCDVC 358
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BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000041914.1 (SMESG000041914.1)

HSP 1 Score: 456.062 bits (1172), Expect = 7.029e-157
Identity = 229/362 (63.26%), Postives = 287/362 (79.28%), Query Frame = 1 
Query:  295 MENNSKSVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLLDNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEKRRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNTIDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFLINHIMIXXXXXXXXXXXXXIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQNLPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTAIEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIKKIETEKLFCDVC 1380
            MEN +  +  P  R +YL+CVF+KI K+DTVNE YS EIFL++KWREPLLD  + I +  LSS+WNPKI+I NIF+ETKS +S EV ++ K+ EAYI+EKR+V   F+E LELQHFPFDCQDLS+TV+T++ I+EVKM ECPH+ S +NTIDGM+SQEW+L+ HV+VESK ++ND NIG +ERQ + FTCRA+R+FKYFLIN+ MISSMF+LLTFTSF I   TNT+ RL LCMT LLTSVTFKVAVSQNLPKIPYLTYLDK ILGNI+MIM  CIWHA TSL+    +F  ++   TTA++ IE  +IP++++FY +A+L  GL IYFDAGKRRREM  KD+EF+  + KI   K  CD+C
Sbjct:    1 MENKAFVIEIPAPRQIYLKCVFLKILKIDTVNEVYSGEIFLEAKWREPLLDQSNYIDNQDLSSYWNPKIAISNIFVETKSLVSREVVFANKSGEAYISEKRKVRATFQETLELQHFPFDCQDLSVTVATDHSIDEVKMFECPHNKSTVNTIDGMDSQEWSLFNHVQVESKIILNDYNIGSKERQIIVFTCRAARQFKYFLINNFMISSMFYLLTFTSFGIQV-TNTFGRLSLCMTVLLTSVTFKVAVSQNLPKIPYLTYLDKTILGNIIMIMITCIWHALTSLW----LFHLSNNEATTALKNIESGIIPAILIFYLIALLIFGLIIYFDAGKRRREMKGKDIEFNRALDKILIAKSSCDIC 357
The following BLAST results are available for this feature:
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GABRB39.043e-823.16gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB31.053e-723.51gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB31.561e-723.51gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB31.662e-723.51gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB25.770e-722.46gamma-aminobutyric acid type A receptor beta2 subu... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG89161.097e-622.30gene:FBgn0030707 transcript:FBtr0301233[more]
CG89161.404e-622.30gene:FBgn0030707 transcript:FBtr0301232[more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gabrg11.164e-724.29gamma-aminobutyric acid type A receptor gamma1 sub... [more]
gabrg11.800e-724.29gamma-aminobutyric acid type A receptor gamma1 sub... [more]
gabrb13.246e-722.81gamma-aminobutyric acid type A receptor beta1 subu... [more]
gabrb46.046e-721.86gamma-aminobutyric acid type A receptor beta4 subu... [more]
gabrb2a1.013e-622.79gamma-aminobutyric acid type A receptor beta2 subu... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000020814.16.415e-923.21gamma-aminobutyric acid type A receptor theta subu... [more]
ENSXETT00000020832.16.573e-923.21gamma-aminobutyric acid type A receptor theta subu... [more]
ENSXETT00000004017.12.106e-823.88gamma-aminobutyric acid (GABA) A receptor, beta 1 ... [more]
dusp51.708e-722.81dual specificity phosphatase 5 [Source:Xenbase;Acc... [more]
gabrb21.717e-623.34gamma-aminobutyric acid (GABA) A receptor, beta 2 ... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gabrb37.261e-823.16gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Gabrb39.777e-823.51gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Gabrb31.065e-723.51gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Glra43.172e-723.31glycine receptor, alpha 4 subunit [Source:MGI Symb... [more]
Glra15.726e-723.85glycine receptor, alpha 1 subunit [Source:MGI Symb... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P19019|GBRB3_CHICK1.421e-724.74Gamma-aminobutyric acid receptor subunit beta-3 OS... [more]
sp|P28472|GBRB3_HUMAN4.343e-723.16Gamma-aminobutyric acid receptor subunit beta-3 OS... [more]
sp|P63079|GBRB3_RAT5.079e-723.16Gamma-aminobutyric acid receptor subunit beta-3 OS... [more]
sp|P63080|GBRB3_MOUSE5.079e-723.16Gamma-aminobutyric acid receptor subunit beta-3 OS... [more]
sp|P24045|GBRB4_CHICK2.055e-622.86Gamma-aminobutyric acid receptor subunit beta-4 OS... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0RSR94.686e-7040.05Uncharacterized protein OS=Fasciola hepatica OX=61... [more]
A0A3R7CFX96.206e-7038.81Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
A0A075A8W67.710e-6838.79Uncharacterized protein OS=Opisthorchis viverrini ... [more]
R7VF521.527e-6637.97Neur_chan_LBD domain-containing protein OS=Capitel... [more]
A0A5K4FCR62.121e-6639.38Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gabrb12.157e-722.81gamma-aminobutyric acid type A receptor beta1 subu... [more]
gabrb2a5.369e-723.34gamma-aminobutyric acid type A receptor beta2 subu... [more]
gabrb2a6.146e-723.34gamma-aminobutyric acid type A receptor beta2 subu... [more]
GABRB21.099e-623.00gamma-aminobutyric acid receptor subunit beta-2 [S... [more]
gabrb31.193e-622.94gamma-aminobutyric acid type A receptor beta3 subu... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
glra22.850e-622.56glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO327901.404e-2328.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO354101.021e-925.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO268595.568e-834.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO431474.837e-723.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gabrb2a1.378e-721.91gamma-aminobutyric acid type A receptor beta2 subu... [more]
gabrb12.433e-722.03gamma-aminobutyric acid type A receptor beta1 subu... [more]
GABRB22.840e-722.46gamma-aminobutyric acid receptor subunit beta-2 [S... [more]
GABRB23.017e-722.46gamma-aminobutyric acid receptor subunit beta-2 [S... [more]
gabrg16.766e-723.89gamma-aminobutyric acid type A receptor gamma1 sub... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000041829.10.000e+0100.00SMESG000041829.1[more]
SMESG000041818.10.000e+075.69SMESG000041818.1[more]
SMESG000041796.17.539e-17169.89SMESG000041796.1[more]
SMESG000064433.14.439e-16971.76SMESG000064433.1[more]
SMESG000041914.17.029e-15763.26SMESG000041914.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033894 ID=SMED30033894|Name=Neur_chan_LBD domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1935bp
AAAATATGTGATTCTAAAAATTAATTTATTTCTTATTTAAATCATTTTTT
CTGACAAAAAACTAAAGGAAATAATAATTATAATGTCAAAATAATGGCAT
ATTTGTTTTTTTCTATCCCACGGAGAAGGGTGAATATTAATAAAAAAATA
AAAACTACATTGTGTCAGTTATTGGCGTTGGAAATAATACAATAGACATG
ACAACCAATAATATACCAATGAATTTTATTGGATAAAATGTTTTCTGTAG
AAATAATAAATAAATTTTAAATACTAATCTGTGATACCAATAAAATGGAA
AACAATTCAAAGTCAGTCAACAAACCCGTTGCAAGACTTGTATATCTTCG
ATGCGTCTTTATCAAAATATTCAAAGTTGATACAGTCAATGAATTTTATT
CTGCGGAAATATTTCTTCAATCTAAATGGCGAGAACCGCTATTGGATAAC
AGATCAGACATTAAAGACATCAGTTTGTCTAGCTTTTGGAATCCAAAAAT
TTCAATAGAAAACATTTTTATGGAAACGAAATCTTCAATTTCTCACGAAG
TCTCCTATTCTGGCAAGGCGCGTGAAGCTTACATTACAGAAAAAAGGCGT
GTGTCTGGCGGCTTTCGTGAAGTTTTAGAATTGCAACACTTTCCGTTTGA
TTGCCAAGATTTATCAATAACAGTCTCCACAGAATATCCCATAAATGAAG
TAAAAATGCTTGAATGTCCGCACGATCTTAGCAAATTGAACACAATTGAT
GGAATGGAATCACAAGAATGGAATTTATATGAGCATGTTGAGGTTGAAAG
TAAAACTGTCATAAATGACTGCAATATTGGTCCAAGAGAGCGCCAAACAA
TGACTTTCACATGTCGCGCAAGCCGAAGATTTAAATATTTTTTGATTAAT
CATATTATGATAAGTTCAATGTTTTTCCTTTTGACATTCACCAGTTTTTC
TATTGCACCTCAAACAAACACATATTACCGATTAGGTTTGTGTATGACCA
CTCTTTTGACAAGTGTCACTTTCAAAGTTGCTGTCAGTCAAAATCTACCA
AAAATTCCTTATTTGACATATTTGGACAAGGCAATTCTGGGTAACATTGT
CATGATAATGTGTCTTTGTATTTGGCATGCTTCGACATCGTTGTTTTTTC
TTACAAAAATATTTTCTGACAATAGTACTATAACAACAACAGCAATTGAA
GGAATAGAGAAATACTTAATTCCAAGCTTAGTAGTATTTTACGGATTGGC
AATACTTGCGGTAGGTCTCACAATATACTTTGATGCTGGCAAAAGAAGAA
GAGAAATGATCGCAAAAGACGTAGAATTTAGTGAAATGATAAAGAAAATA
GAAACAGAAAAATTATTTTGTGATGTTTGCTAAAACCACTTCAGTTGCCT
TTATTATTCACACCATATTATAACAGATACGCTGAATTTTATTTTCATCA
TAGAATTTCATAACATTTTTACTGTTTTTTTACCGATTTGACCTTTTGAC
AAAACTACCAGTATATTTATCAAAATGGCTGTGATGTGAATAAATTTATT
TATACTTTCAGCCTTTAATTTCCTTCTATATTTACCTATAACAAAATGTG
TGACAACAATTTAAAAGTTATTCATGATCAAAAATCACGGCAATAAATCA
AAATGCACCATTTACAAATTGAATATGCTATAAGCAGACAATTTGTACAT
ATACTCATGTGATCTCATTTTGGTGTCATTGAAAATATGTAGATGCTTCA
TTAACTCAAGGTTTAGTACACATTTGTCTGTTTATAAACGTCGGTTCTTC
ATGATATGTTAAATAGACACTTATAGTGGTTCCTTTGTGTGACATTGTCA
GCAATTGTTATCTATGTATGCCTCGGTTGTTGTTCACATTTTTATCTGTT
TGAAGTGGATCGAATTTGGAAATGATGTGTAGCTG
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protein sequence of SMED30033894-orf-1

>SMED30033894-orf-1 ID=SMED30033894-orf-1|Name=SMED30033894-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=363bp
MENNSKSVNKPVARLVYLRCVFIKIFKVDTVNEFYSAEIFLQSKWREPLL
DNRSDIKDISLSSFWNPKISIENIFMETKSSISHEVSYSGKAREAYITEK
RRVSGGFREVLELQHFPFDCQDLSITVSTEYPINEVKMLECPHDLSKLNT
IDGMESQEWNLYEHVEVESKTVINDCNIGPRERQTMTFTCRASRRFKYFL
INHIMISSMFFLLTFTSFSIAPQTNTYYRLGLCMTTLLTSVTFKVAVSQN
LPKIPYLTYLDKAILGNIVMIMCLCIWHASTSLFFLTKIFSDNSTITTTA
IEGIEKYLIPSLVVFYGLAILAVGLTIYFDAGKRRREMIAKDVEFSEMIK
KIETEKLFCDVC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004888transmembrane signaling receptor activity
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000025nervous system
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR036734Neur_chan_lig-bd_sf
IPR006201Neur_channel
IPR036719Neuro-gated_channel_TM_sf
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
GO:0034220ion transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 16..194
e-value: 1.4E-7
score: 31.2
NoneNo IPR availableGENE3DG3DSA:1.20.58.390coord: 197..326
e-value: 2.7E-13
score: 52.0
NoneNo IPR availablePANTHERPTHR18945:SF768coord: 16..292
NoneNo IPR availableCDDcd18988LGIC_ECD_bactcoord: 22..195
e-value: 2.35663E-15
score: 71.555
NoneNo IPR availableCDDcd19050LGIC_TM_bactcoord: 204..271
e-value: 3.06583E-10
score: 55.2922
NoneNo IPR availableTMHMMTMhelixcoord: 226..248
NoneNo IPR availableTMHMMTMhelixcoord: 307..329
NoneNo IPR availableTMHMMTMhelixcoord: 199..221
NoneNo IPR availableTMHMMTMhelixcoord: 265..287
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilyGENE3DG3DSA:2.70.170.10coord: 7..192
e-value: 3.1E-15
score: 58.2
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilySUPERFAMILYSSF63712Nicotinic receptor ligand binding domain-likecoord: 13..189
IPR006201Neurotransmitter-gated ion-channelPANTHERPTHR18945NEUROTRANSMITTER GATED ION CHANNELcoord: 16..292
IPR036719Neurotransmitter-gated ion-channel transmembrane domain superfamilySUPERFAMILYSSF90112Neurotransmitter-gated ion-channel transmembrane porecoord: 198..275