Pyridine nucleotide-disulfide oxidoreductase
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033880 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Fly
Match: CG4199 (gene:FBgn0025628 transcript:FBtr0300254) HSP 1 Score: 51.2174 bits (121), Expect = 1.095e-6 Identity = 26/87 (29.89%), Postives = 48/87 (55.17%), Query Frame = 2 Query: 467 NTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLVKDNGEIFI 724 +T+VLL++ + ++A KC H GAPL G + G ++CPWH FNL+ +++P ++ +P Y+ V + G++ + Sbjct: 79 DTRVLLVKQNDRLLAVGAKCTHYGAPLQTGAL-----GLGRVRCPWHGACFNLENGDIEDFPGLDSLP-----CYRVEVGNEGQVML 155
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Fly
Match: CG4199 (gene:FBgn0025628 transcript:FBtr0070336) HSP 1 Score: 51.2174 bits (121), Expect = 1.095e-6 Identity = 26/87 (29.89%), Postives = 48/87 (55.17%), Query Frame = 2 Query: 467 NTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLVKDNGEIFI 724 +T+VLL++ + ++A KC H GAPL G + G ++CPWH FNL+ +++P ++ +P Y+ V + G++ + Sbjct: 79 DTRVLLVKQNDRLLAVGAKCTHYGAPLQTGAL-----GLGRVRCPWHGACFNLENGDIEDFPGLDSLP-----CYRVEVGNEGQVML 155
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Fly
Match: CG4199 (gene:FBgn0025628 transcript:FBtr0070334) HSP 1 Score: 51.2174 bits (121), Expect = 1.095e-6 Identity = 26/87 (29.89%), Postives = 48/87 (55.17%), Query Frame = 2 Query: 467 NTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLVKDNGEIFI 724 +T+VLL++ + ++A KC H GAPL G + G ++CPWH FNL+ +++P ++ +P Y+ V + G++ + Sbjct: 79 DTRVLLVKQNDRLLAVGAKCTHYGAPLQTGAL-----GLGRVRCPWHGACFNLENGDIEDFPGLDSLP-----CYRVEVGNEGQVML 155
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Fly
Match: CG4199 (gene:FBgn0025628 transcript:FBtr0300255) HSP 1 Score: 51.2174 bits (121), Expect = 1.095e-6 Identity = 26/87 (29.89%), Postives = 48/87 (55.17%), Query Frame = 2 Query: 467 NTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLVKDNGEIFI 724 +T+VLL++ + ++A KC H GAPL G + G ++CPWH FNL+ +++P ++ +P Y+ V + G++ + Sbjct: 79 DTRVLLVKQNDRLLAVGAKCTHYGAPLQTGAL-----GLGRVRCPWHGACFNLENGDIEDFPGLDSLP-----CYRVEVGNEGQVML 155
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Fly
Match: CG4199 (gene:FBgn0025628 transcript:FBtr0070335) HSP 1 Score: 51.2174 bits (121), Expect = 1.095e-6 Identity = 26/87 (29.89%), Postives = 48/87 (55.17%), Query Frame = 2 Query: 467 NTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLVKDNGEIFI 724 +T+VLL++ + ++A KC H GAPL G + G ++CPWH FNL+ +++P ++ +P Y+ V + G++ + Sbjct: 79 DTRVLLVKQNDRLLAVGAKCTHYGAPLQTGAL-----GLGRVRCPWHGACFNLENGDIEDFPGLDSLP-----CYRVEVGNEGQVML 155
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Zebrafish
Match: si:ch73-314g15.3 (si:ch73-314g15.3 [Source:ZFIN;Acc:ZDB-GENE-030616-19]) HSP 1 Score: 60.4622 bits (145), Expect = 1.201e-9 Identity = 28/72 (38.89%), Postives = 42/72 (58.33%), Query Frame = 2 Query: 509 ACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFI 724 A ++ CPH+G PL +GDIE+L NG L CPWH+F F+L+ +Q ++Y V D G+++I Sbjct: 57 AMDSSCPHEGGPLEQGDIEDLGNGKLALICPWHYFDFSLETGSSSS-------GLQNQVYDVRVLD-GKVYI 120
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Zebrafish
Match: si:ch73-314g15.3 (si:ch73-314g15.3 [Source:ZFIN;Acc:ZDB-GENE-030616-19]) HSP 1 Score: 59.3066 bits (142), Expect = 2.907e-9 Identity = 27/70 (38.57%), Postives = 41/70 (58.57%), Query Frame = 2 Query: 515 ENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFI 724 ++ CPH+G PL +GDIE+L NG L CPWH+F F+L+ +Q ++Y V D G+++I Sbjct: 2 DSSCPHEGGPLEQGDIEDLGNGKLALICPWHYFDFSLETGSSSS-------GLQNQVYDVRVLD-GKVYI 63
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Zebrafish
Match: RFESD (Rieske domain-containing protein-like [Source:NCBI gene;Acc:559859]) HSP 1 Score: 55.0694 bits (131), Expect = 9.317e-9 Identity = 32/103 (31.07%), Postives = 50/103 (48.54%), Query Frame = 2 Query: 455 ETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVE-----LMPEMQLKLYK----TLVKDNGEIFITFND 736 +++ VL++ A + +C H G PL EGDIE+ +G + CPWH +K L + V+ L P K K T+ + NG++F+T ND Sbjct: 34 KSIGGRDVLVIYHQGHFYAIDARCYHSGGPLQEGDIEDF-DGRTCIVCPWHKYKITLAEGEGLYQAVDPTVKPLKPTWCSKGIKQRIHTVTESNGDLFLTLND 135
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Zebrafish
Match: aifm4 (apoptosis inducing factor mitochondria associated 4 [Source:ZFIN;Acc:ZDB-GENE-070112-2282]) HSP 1 Score: 51.6026 bits (122), Expect = 2.594e-7 Identity = 32/99 (32.32%), Postives = 54/99 (54.55%), Query Frame = 2 Query: 452 EETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLVKDNGEIFITFNDFNL 745 E V+ K+LL+R E A C H GAPL +G + GDR+ +CP+H FN +E+P ++ +P+ ++K+ D G++++T + NL Sbjct: 26 EVLVDENKILLVRNNGEFTAVGGLCSHYGAPLIKGTL----IGDRV-RCPFHGACFNTKTGDIEEFPGLDCLPKFKVKV------DGGKVYVTSDQKNL 113
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Zebrafish
Match: aifm5 (apoptosis inducing factor mitochondria associated 5 [Source:ZFIN;Acc:ZDB-GENE-091118-96]) HSP 1 Score: 53.1434 bits (126), Expect = 3.398e-7 Identity = 29/80 (36.25%), Postives = 46/80 (57.50%), Query Frame = 2 Query: 449 LEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKL 685 +E V + VLL+R A N+C H GAPL+EG + +G R+ +CPWH FN+ +EYP ++ +P ++K+ Sbjct: 3 MEVEVGDHNVLLVRCDGVYSAISNQCTHYGAPLSEGVL----SGCRV-RCPWHGSCFNVKTGDLEEYPGIDCLPCHKVKV 77
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Xenopus
Match: plag1 (PLAG1 zinc finger [Source:Xenbase;Acc:XB-GENE-868443]) HSP 1 Score: 60.8474 bits (146), Expect = 1.314e-9 Identity = 29/73 (39.73%), Postives = 41/73 (56.16%), Query Frame = 2 Query: 410 GTKNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLD 628 G K + CT E + VL+ ++ A ++ CPH+G PL +GDIE L +G L CPWH+F+F LD Sbjct: 25 GEKRSFKATCTKLFSEDGEHL-VLIHTTDDKFYAMDSSCPHEGGPLEQGDIEELCDGRLALTCPWHYFEFCLD 96
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Xenopus
Match: plag1 (PLAG1 zinc finger [Source:Xenbase;Acc:XB-GENE-868443]) HSP 1 Score: 60.8474 bits (146), Expect = 1.583e-9 Identity = 29/73 (39.73%), Postives = 41/73 (56.16%), Query Frame = 2 Query: 410 GTKNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLD 628 G K + CT E + VL+ ++ A ++ CPH+G PL +GDIE L +G L CPWH+F+F LD Sbjct: 25 GEKRSFKATCTKLFSEDGEHL-VLIHTTDDKFYAMDSSCPHEGGPLEQGDIEELCDGRLALTCPWHYFEFCLD 96
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Xenopus
Match: nelfb (negative elongation factor complex member B [Source:Xenbase;Acc:XB-GENE-5814644]) HSP 1 Score: 52.373 bits (124), Expect = 9.038e-7 Identity = 29/77 (37.66%), Postives = 45/77 (58.44%), Query Frame = 2 Query: 473 KVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLV 700 K LL++ E A +KCPH GAPL +G LS G ++CPWH FN+ +++P ++ +P+ Q+K+ K V Sbjct: 92 KALLVKQNGEYYAMGHKCPHYGAPLVKG---VLSKGR--VRCPWHGACFNIATGDIEDFPGLDALPKFQVKIEKERV 163
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Xenopus
Match: nelfb (negative elongation factor complex member B [Source:Xenbase;Acc:XB-GENE-5814644]) HSP 1 Score: 52.373 bits (124), Expect = 9.054e-7 Identity = 29/77 (37.66%), Postives = 45/77 (58.44%), Query Frame = 2 Query: 473 KVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLV 700 K LL++ E A +KCPH GAPL +G LS G ++CPWH FN+ +++P ++ +P+ Q+K+ K V Sbjct: 89 KALLVKQNGEYYAMGHKCPHYGAPLVKG---VLSKGR--VRCPWHGACFNIATGDIEDFPGLDALPKFQVKIEKERV 160
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Xenopus
Match: nelfb (negative elongation factor complex member B [Source:Xenbase;Acc:XB-GENE-5814644]) HSP 1 Score: 52.373 bits (124), Expect = 9.864e-7 Identity = 29/77 (37.66%), Postives = 45/77 (58.44%), Query Frame = 2 Query: 473 KVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLV 700 K LL++ E A +KCPH GAPL +G LS G ++CPWH FN+ +++P ++ +P+ Q+K+ K V Sbjct: 92 KALLVKQNGEYYAMGHKCPHYGAPLVKG---VLSKGR--VRCPWHGACFNIATGDIEDFPGLDALPKFQVKIEKERV 163
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. TrEMBL
Match: V4AL65 (Rieske domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_152940 PE=4 SV=1) HSP 1 Score: 78.9518 bits (193), Expect = 7.169e-14 Identity = 45/117 (38.46%), Postives = 62/117 (52.99%), Query Frame = 2 Query: 380 SRAKTDSSVYGTKNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITF 730 + K ++V TK + N G N KV L R G V A ++KCPH G PL+ GDIE L NG+ ++CPWH +KF+L+ G E+P Y+ V + GEI+I F Sbjct: 25 QKCKHTTAVINTKGLLNNNEKNGHLVECNEEKVALFRHGNNVYAVKDKCPHAGGPLHLGDIEELPNGNLCVKCPWHSWKFDLE-TGHAEFPKG--QSKTAVTYRVKVTETGEIYIGF 138
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. TrEMBL
Match: A0A210PYV8 (Rieske domain-containing protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT18584 PE=4 SV=1) HSP 1 Score: 78.1814 bits (191), Expect = 1.336e-13 Identity = 48/143 (33.57%), Postives = 67/143 (46.85%), Query Frame = 2 Query: 335 FFSSRKTAIKNKLDLS----RAKTDSSVYGTKNTK-DKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMP---EMQLKLYKTLVKDNGEIFITFNDF 739 FF ++ K D + R KT S KN +N G N K+ L R GE V A + KCPH G PL+ GDIE + G ++CPWH ++F+LD MP ++ + +Y V +G I I F+ F Sbjct: 7 FFPVKELTYKELFDWADPVQRYKTSSVSVPRKNGLLRQNSRTGSLVDCNKMKIALFRHGERVFAVDEKCPHAGGPLHLGDIEEIPGGGLCVRCPWHSWRFDLDTGK------STMPRGRDLLMAIYPVRVDQDGIISIGFDKF 143
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. TrEMBL
Match: A0A2G8KEW3 (Putative Rieske domain-containing protein-like OS=Stichopus japonicus OX=307972 GN=BSL78_16582 PE=4 SV=1) HSP 1 Score: 78.5666 bits (192), Expect = 1.446e-13 Identity = 40/112 (35.71%), Postives = 58/112 (51.79%), Query Frame = 2 Query: 416 KNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLK---LYKTLVKDNGEIFITFNDFN 742 + T + G VN +V L R GEEV A + KCPH+G PL+ GDIE L + ++CPWHH+ +L + P + + +Y T V D+G IF+ F F+ Sbjct: 56 RETTGRKLKTGRAVKVNGEEVALFRLGEEVFAVKEKCPHQGGPLHLGDIEVLPDRSLCVRCPWHHWCVDLASGRVRR------PSGRTQTTNVYMTKVTDDGNIFVGFKHFS 161
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. TrEMBL
Match: K1PS30 (Rieske domain-containing protein OS=Crassostrea gigas OX=29159 GN=CGI_10006737 PE=4 SV=1) HSP 1 Score: 77.0258 bits (188), Expect = 4.192e-13 Identity = 35/108 (32.41%), Postives = 59/108 (54.63%), Query Frame = 2 Query: 419 NTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITFNDFN 742 + +N G + N ++ + R+ + V A + KCPH G PL+ GDIE L ++CPWH +KF+LD K+ P + +Y +VK++G++ I F+ F+ Sbjct: 42 GLRRQNSKTGTLVSCNEQQIAVFRYHDRVYAIKEKCPHLGGPLHLGDIEELPGNTLCVRCPWHSWKFDLDTGLLKQ---PKRPGVSSVVYPVIVKEDGKLMIGFDQFD 146
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. TrEMBL
Match: A0A1S3H7W7 (Rieske domain-containing protein OS=Lingula unguis OX=7574 GN=LOC106152883 PE=4 SV=1) HSP 1 Score: 75.8702 bits (185), Expect = 9.359e-13 Identity = 46/145 (31.72%), Postives = 72/145 (49.66%), Query Frame = 2 Query: 314 STSIDNSFFSSRKTAIKNKLDLSRAKTDSSVYGT--KNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITFNDFN 742 S++ D FF + D S A+ + T + + ++ G+ VN TK+ L R+G+++ A KCPH G PL+ GDIE L + ++CPWH +KF+L K G ++P + +Y V G I I F F+ Sbjct: 2 SSNGDKIFFPVKGVNFYELFDWSNAEERCKLTATDARKLRRQSSQSGVRVEVNETKIALFRYGDQLHAVNEKCPHAGGPLHIGDIEELPDFSVCVRCPWHGWKFDL-KTGRCKHPS--GEQRCTIVYAVRVDTQGNIEIGFESFS 143
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Cavefish
Match: si:ch73-314g15.3 (uncharacterized protein HI_0077-like [Source:NCBI gene;Acc:103033616]) HSP 1 Score: 60.8474 bits (146), Expect = 9.584e-10 Identity = 27/72 (37.50%), Postives = 43/72 (59.72%), Query Frame = 2 Query: 509 ACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFI 724 A ++ CPH+G PL++GDIE+L +G L CPWH+F F+L+ +Q ++Y V D G+++I Sbjct: 85 AMDSSCPHEGGPLDQGDIEDLGDGKLALVCPWHYFDFSLETGASSS-------GLQNQVYDVRVVD-GKVYI 148
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Cavefish
Match: ENSAMXT00000043267.1 (Rieske domain-containing protein-like [Source:NCBI gene;Acc:107197454]) HSP 1 Score: 51.6026 bits (122), Expect = 1.391e-7 Identity = 34/102 (33.33%), Postives = 46/102 (45.10%), Query Frame = 2 Query: 458 TVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVE-----LMPEMQLKLYKTLVKD----NGEIFITFND 736 +VN VL+L + A + C H G PL GDIE +G + CPWH +K L + V+ L P K K V +GE+F+T ND Sbjct: 30 SVNGRDVLVLHHQGSLHALDLHCYHSGGPLQCGDIEEF-DGRLCIVCPWHKYKITLAEGEGLYQAVDPSIRPLRPVWSSKGVKQRVHRVTEVDGEVFVTLND 130
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Cavefish
Match: aifm5 (apoptosis inducing factor mitochondria associated 5 [Source:ZFIN;Acc:ZDB-GENE-091118-96]) HSP 1 Score: 52.7582 bits (125), Expect = 3.872e-7 Identity = 31/95 (32.63%), Postives = 51/95 (53.68%), Query Frame = 2 Query: 449 LEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITFN 733 +E V + +LL++ E A N+C H GAPLN + +G+R+ +CPWH FN+ +EYP L+ +K V+D ++++T N Sbjct: 25 MEVDVGDHNILLVKCEGEYSAIGNQCTHYGAPLN-----TVLSGNRV-RCPWHGACFNVKTGDMEEYP----AMDSLRCHKVKVQDK-KVYVTVN 108
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Sea Lamprey
Match: si:ch73-314g15.3 (si:ch73-314g15.3 [Source:ZFIN;Acc:ZDB-GENE-030616-19]) HSP 1 Score: 57.3806 bits (137), Expect = 1.891e-9 Identity = 22/42 (52.38%), Postives = 28/42 (66.67%), Query Frame = 2 Query: 509 ACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKN 634 A ++ CPH+G PL GDIE+L +G L CPWHHF F L+ Sbjct: 22 AMDSACPHEGGPLELGDIEDLGSGKLALICPWHHFDFCLNTG 63
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Sea Lamprey
Match: si:ch211-212d10.2 (si:ch211-212d10.2 [Source:ZFIN;Acc:ZDB-GENE-050208-516]) HSP 1 Score: 52.373 bits (124), Expect = 7.510e-9 Identity = 28/69 (40.58%), Postives = 44/69 (63.77%), Query Frame = 2 Query: 524 CPH--KGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFI 724 CPH KG PLNEGDIE++ GD + CPWH+++F++ K G + +Q ++Y+ V+D G +F+ Sbjct: 53 CPHQDKGGPLNEGDIEDIG-GDLKITCPWHYYQFDV-KTGKSD------TGLQQRVYEVKVED-GLVFV 112
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Medaka
Match: aifm5 (apoptosis-inducing factor 3 [Source:NCBI gene;Acc:101161742]) HSP 1 Score: 51.9878 bits (123), Expect = 6.003e-7 Identity = 30/99 (30.30%), Postives = 55/99 (55.56%), Query Frame = 2 Query: 452 EETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLVKDNGEIFITFNDFNL 745 E + + VLL R + A N+C H GAPL++G + +G+R+ +CPWH FN+ +E+P ++ +P ++K+ N ++++T N +L Sbjct: 33 EVEIGHHSVLLTRHEGKYSALGNQCTHYGAPLSQGVV----SGNRV-RCPWHGSCFNICTGDLEEFPGIDSLPCHKVKI------QNSKVYVTVNRKDL 120
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Medaka
Match: aifm3 (apoptosis inducing factor mitochondria associated 3 [Source:NCBI gene;Acc:101158534]) HSP 1 Score: 50.0618 bits (118), Expect = 2.754e-6 Identity = 27/81 (33.33%), Postives = 46/81 (56.79%), Query Frame = 2 Query: 452 EETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYK 691 E + + + LL++ E A +KCPH GAPL +G LS G ++CPWH FN+ +++P ++ +P Q+++ K Sbjct: 85 EVDLGSGRALLIKEHGEFFAMGHKCPHYGAPLVKG---VLSKGH--VRCPWHGACFNVATGDIEDFPGLDSLPVFQVRVEK 160
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Medaka
Match: aifm3 (apoptosis inducing factor mitochondria associated 3 [Source:NCBI gene;Acc:101158534]) HSP 1 Score: 50.0618 bits (118), Expect = 2.767e-6 Identity = 27/81 (33.33%), Postives = 46/81 (56.79%), Query Frame = 2 Query: 452 EETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYK 691 E + + + LL++ E A +KCPH GAPL +G LS G ++CPWH FN+ +++P ++ +P Q+++ K Sbjct: 85 EVDLGSGRALLIKEHGEFFAMGHKCPHYGAPLVKG---VLSKGH--VRCPWHGACFNVATGDIEDFPGLDSLPVFQVRVEK 160
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Medaka
Match: aifm4 (apoptosis-inducing factor 3 [Source:NCBI gene;Acc:101169960]) HSP 1 Score: 49.2914 bits (116), Expect = 5.295e-6 Identity = 28/101 (27.72%), Postives = 56/101 (55.45%), Query Frame = 2 Query: 452 EETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYP-VELMPEMQLKLYKTLVKDNGEIFITFNDFNLNF 751 E TV + KVL++R + A +C H APL +G + G+R+ +CP+H FN+ ++YP ++ +P ++K+ ++G+++++ N +L Sbjct: 33 EVTVQDQKVLVVRTQGQYFAVGGRCSHYNAPLIKGAL----VGERV-RCPFHGACFNVRTGDIEDYPGLDSLPTYKVKV------EDGKVYVSINQKSLKL 122
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Medaka
Match: ENSORLT00000007386.2 (Rieske domain-containing protein [Source:NCBI gene;Acc:101157781]) HSP 1 Score: 47.3654 bits (111), Expect = 7.445e-6 Identity = 29/97 (29.90%), Postives = 47/97 (48.45%), Query Frame = 2 Query: 476 VLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNL-DKNGFKEY---PVELMPEMQL-------KLYKTLVKDNGEIFITFN 733 VL+L ++ A + +C H G L GDIE NG + CPWH +K L + G + P + P +++K + + NG++F+T N Sbjct: 81 VLILYHDRQLYAMDKRCYHSGGELQHGDIEEF-NGRLCIVCPWHSYKITLAEGEGLYQAVDDPTKKPPRTHWRSKGVKQRIHK-VTEINGDVFVTLN 175
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Planmine SMEST
Match: SMESG000046042.1 (SMESG000046042.1) HSP 1 Score: 470.7 bits (1210), Expect = 1.677e-168 Identity = 231/232 (99.57%), Postives = 231/232 (99.57%), Query Frame = 2 Query: 56 MSRNMIYVPKTLLKPYGLNEVCIPFKMDKNRVRNHIIINDENSNQIPTKKYKKTDNSKSESPEFIFKVPNLKFNDLKDINKMIQSKSTSIDNSFFSSRKTAIKNKLDLSRAKTDSSVYGTKNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITFNDFNLNF 751 MSRNMIYVPKTLLKPYGLNEVCIPFKMDKNRVRNHIIINDENSNQIPTKKYKKTDN KSESPEFIFKVPNLKFNDLKDINKMIQSKSTSIDNSFFSSRKTAIKNKLDLSRAKTDSSVYGTKNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITFNDFNLNF Sbjct: 1 MSRNMIYVPKTLLKPYGLNEVCIPFKMDKNRVRNHIIINDENSNQIPTKKYKKTDNRKSESPEFIFKVPNLKFNDLKDINKMIQSKSTSIDNSFFSSRKTAIKNKLDLSRAKTDSSVYGTKNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITFNDFNLNF 232
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Planmine SMEST
Match: SMESG000046042.1 (SMESG000046042.1) HSP 1 Score: 461.84 bits (1187), Expect = 4.065e-165 Identity = 227/228 (99.56%), Postives = 227/228 (99.56%), Query Frame = 2 Query: 68 MIYVPKTLLKPYGLNEVCIPFKMDKNRVRNHIIINDENSNQIPTKKYKKTDNSKSESPEFIFKVPNLKFNDLKDINKMIQSKSTSIDNSFFSSRKTAIKNKLDLSRAKTDSSVYGTKNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITFNDFNLNF 751 MIYVPKTLLKPYGLNEVCIPFKMDKNRVRNHIIINDENSNQIPTKKYKKTDN KSESPEFIFKVPNLKFNDLKDINKMIQSKSTSIDNSFFSSRKTAIKNKLDLSRAKTDSSVYGTKNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITFNDFNLNF Sbjct: 1 MIYVPKTLLKPYGLNEVCIPFKMDKNRVRNHIIINDENSNQIPTKKYKKTDNRKSESPEFIFKVPNLKFNDLKDINKMIQSKSTSIDNSFFSSRKTAIKNKLDLSRAKTDSSVYGTKNTKDKNCTVGLEETVNNTKVLLLRFGEEVIACENKCPHKGAPLNEGDIENLSNGDRILQCPWHHFKFNLDKNGFKEYPVELMPEMQLKLYKTLVKDNGEIFITFNDFNLNF 228 The following BLAST results are available for this feature:
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Pyridine nucleotide-disulfide oxidoreductase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033880 ID=SMED30033880|Name=Pyridine nucleotide-disulfide oxidoreductase|organism=Schmidtea mediterranea sexual|type=transcript|length=1172bpback to top protein sequence of SMED30033880-orf-1 >SMED30033880-orf-1 ID=SMED30033880-orf-1|Name=SMED30033880-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=233bp MSRNMIYVPKTLLKPYGLNEVCIPFKMDKNRVRNHIIINDENSNQIPTKKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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