slc25a-18

Overview
Nameslc25a-18 (AKN21586.1)
Smed IDSMED30033874
Length (bp)1178
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of slc25a-18 (SMED30033874) t-SNE clustered cells

Violin plots show distribution of expression levels for slc25a-18 (SMED30033874) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc25a-18 (SMED30033874) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc25a-18 (SMED30033874) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30033874

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
neoblastSMED30033874h1SMcG0001320 dd_Smed_v4_3596_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of slc25a-18 vs. Ensembl Human
Match: SLC25A11 (solute carrier family 25 member 11 [Source:HGNC Symbol;Acc:HGNC:10981])

HSP 1 Score: 406.757 bits (1044), Expect = 1.467e-141
Identity = 191/291 (65.64%), Postives = 228/291 (78.35%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNV 1007
            P  VKF FGG AGM AT+FVQPLDLVKNRMQ+SG+    + YK+SF A+  I K EGL  IY+GLSAGLLRQATYTTTRLG+YT LFE+ +  D  PP F+ KA IGM+AG  G+FVGTP EVALIRMT+DGRLP D+RR Y+NVF+AL RI REEGVL LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F+D I  HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++   ++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN AYK +
Sbjct:   20 PKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310          
BLAST of slc25a-18 vs. Ensembl Human
Match: SLC25A11 (solute carrier family 25 member 11 [Source:HGNC Symbol;Acc:HGNC:10981])

HSP 1 Score: 388.652 bits (997), Expect = 1.083e-134
Identity = 182/278 (65.47%), Postives = 218/278 (78.42%), Query Frame = 3
Query:  168 SAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            S  M AT+FVQPLDLVKNRMQ+SG+    + YK+SF A+  I K EGL  IY+GLSAGLLRQATYTTTRLG+YT LFE+ +  D  PP F+ KA IGM+AG  G+FVGTP EVALIRMT+DGRLP D+RR Y+NVF+AL RI REEGVL LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F+D I  HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++   ++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN AY
Sbjct:   19 SPKMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAY 296          
BLAST of slc25a-18 vs. Ensembl Human
Match: SLC25A11 (solute carrier family 25 member 11 [Source:HGNC Symbol;Acc:HGNC:10981])

HSP 1 Score: 332.413 bits (851), Expect = 4.664e-113
Identity = 154/234 (65.81%), Postives = 185/234 (79.06%), Query Frame = 3
Query:  309 LFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNV 1007
            LF   +GLSAGLLRQATYTTTRLG+YT LFE+ +  D  PP F+ KA IGM+AG  G+FVGTP EVALIRMT+DGRLP D+RR Y+NVF+AL RI REEGVL LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F+D I  HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++   ++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN AYK +
Sbjct:   26 LFGGLAGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 259          

HSP 2 Score: 56.6102 bits (135), Expect = 1.979e-8
Identity = 43/174 (24.71%), Postives = 78/174 (44.83%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQ--DGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTA-----LFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGR 647
            +K   G +AG        P ++   RM   G+     ++ YK+ F+A+ +IT+ EG+  ++ G    + R       +L  Y+      L   + S +    F       M +GL+ +    P ++A  R+  + R+ +D +  Y+N    L ++VR EG  +LW+G  P   R
Sbjct:   70 LKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCAS----MISGLVTTAASMPVDIAKTRI-QNMRM-IDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYAR 237          
BLAST of slc25a-18 vs. Ensembl Human
Match: SLC25A10 (solute carrier family 25 member 10 [Source:HGNC Symbol;Acc:HGNC:10980])

HSP 1 Score: 192.971 bits (489), Expect = 2.979e-58
Identity = 106/285 (37.19%), Postives = 159/285 (55.79%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIK-QITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPP-SFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            ++ FGG A   A     PLDL+K  +Q      +++  K     +  ++ + +G+ A+YSGLSA L RQ TY+ TR  +Y  + ++ +   + P  F  K  +G  +GL G FVGTP ++  +RM +D +LP  +RRNY +    L R+ REEG+  L+ G      R A+V + QL+ Y QAKQ++L T   +D IF HF AS I+G   T    P+D++KTR+     +N   EY G  +  +   K  G L+ +KG  P  +RL PHTV+TFV LEQ+   +
Sbjct:    9 RWYFGGLASCGAACCTHPLDLLKVHLQ------TQQEVKLRMTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRL-----MNSKGEYQGVFHCAVETAK-LGPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRKNF 281          

HSP 2 Score: 51.2174 bits (121), Expect = 1.230e-6
Identity = 44/174 (25.29%), Postives = 73/174 (41.95%), Query Frame = 3
Query:  135 IPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQ--DGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYT-----ALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLP 635
            +P + K   G  +G+       P DLV  RMQ   +   G ++ Y  + D + ++ + EGL  ++SG +    R A  T  +L  Y       L   + S +    FV        AG   +F+  P +V   R+       M+ +  Y+ VFH      +  G LA ++G +P
Sbjct:   97 LPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVAS----FIAGGCATFLCQPLDVLKTRL-------MNSKGEYQGVFHCAVETAK-LGPLAFYKGLVP 258          
BLAST of slc25a-18 vs. Ensembl Human
Match: SLC25A14 (solute carrier family 25 member 14 [Source:HGNC Symbol;Acc:HGNC:10984])

HSP 1 Score: 188.734 bits (478), Expect = 1.256e-56
Identity = 101/288 (35.07%), Postives = 161/288 (55.90%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKK----AYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNM-TVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMN 989
            N+  F +GG A ++A     P+DL K R+Q+ GQ    +     Y+  F A+ +I K EG+ A+YSG++  LLRQA+Y T ++G+Y +L   F  + +  + +     G+ +G+I S +  PT+V  IRM + G L         ++  +   I ++EG   LWRG +PT  RAA+V   +L  Y   K+ ++ + +  D I  HF +S   G    +AS PVD+V+TR+ N   +V  V  Y G ++  +++ KHEG  +L+KGF P +LRLGP  +I F+  EQ+ 
Sbjct:    5 NWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQG------SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 286          
BLAST of slc25a-18 vs. Ensembl Celegans
Match: misc-1 (Mitochondrial 2-oxoglutarate/malate carrier protein [Source:UniProtKB/Swiss-Prot;Acc:P90992])

HSP 1 Score: 406.757 bits (1044), Expect = 3.587e-142
Identity = 194/288 (67.36%), Postives = 232/288 (80.56%), Query Frame = 3
Query:  135 IPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            +PN VKFAFGG+AGM ATL VQPLDLVKNRMQ+SG  G KK Y+SS  A+  I KNEG+FA+Y+GLSAGLLRQATYTTTRLG Y  L E+F+ KDKP SF  KA +GM+AG IGSFVGTP E+ALIRMT DGRLP+++RRNY  V +AL RI +EEGVL LWRGC PT+ RA VVN AQLA+YSQAKQ +L +    DGIF HF ASMISG  TT+ASMPVDI KTRIQ+M V++G  EY  A + + ++ K+EG+ +LWKGFTPY++RLGPHTV+TF++LEQMN AY
Sbjct:    7 VPNVVKFAFGGTAGMGATLVVQPLDLVKNRMQLSGTTG-KKEYRSSMHALTSIMKNEGVFAVYNGLSAGLLRQATYTTTRLGTYAFLLERFTEKDKPLSFGMKAVLGMTAGGIGSFVGTPAEIALIRMTGDGRLPVEQRRNYTGVVNALTRITKEEGVLTLWRGCTPTVLRAMVVNAAQLATYSQAKQALLASGKVQDGIFCHFLASMISGLATTIASMPVDIAKTRIQSMKVIDGKPEYKNAFDVWGKVIKNEGIFALWKGFTPYYMRLGPHTVLTFIILEQMNAAY 293          
BLAST of slc25a-18 vs. Ensembl Celegans
Match: misc-1 (Mitochondrial 2-oxoglutarate/malate carrier protein [Source:UniProtKB/Swiss-Prot;Acc:P90992])

HSP 1 Score: 406.757 bits (1044), Expect = 3.587e-142
Identity = 194/288 (67.36%), Postives = 232/288 (80.56%), Query Frame = 3
Query:  135 IPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            +PN VKFAFGG+AGM ATL VQPLDLVKNRMQ+SG  G KK Y+SS  A+  I KNEG+FA+Y+GLSAGLLRQATYTTTRLG Y  L E+F+ KDKP SF  KA +GM+AG IGSFVGTP E+ALIRMT DGRLP+++RRNY  V +AL RI +EEGVL LWRGC PT+ RA VVN AQLA+YSQAKQ +L +    DGIF HF ASMISG  TT+ASMPVDI KTRIQ+M V++G  EY  A + + ++ K+EG+ +LWKGFTPY++RLGPHTV+TF++LEQMN AY
Sbjct:    7 VPNVVKFAFGGTAGMGATLVVQPLDLVKNRMQLSGTTG-KKEYRSSMHALTSIMKNEGVFAVYNGLSAGLLRQATYTTTRLGTYAFLLERFTEKDKPLSFGMKAVLGMTAGGIGSFVGTPAEIALIRMTGDGRLPVEQRRNYTGVVNALTRITKEEGVLTLWRGCTPTVLRAMVVNAAQLATYSQAKQALLASGKVQDGIFCHFLASMISGLATTIASMPVDIAKTRIQSMKVIDGKPEYKNAFDVWGKVIKNEGIFALWKGFTPYYMRLGPHTVLTFIILEQMNAAY 293          
BLAST of slc25a-18 vs. Ensembl Celegans
Match: slc-25A10 (Oxoglutarate/malate carrier protein; SLC (SoLute Carrier) homolog [Source:UniProtKB/TrEMBL;Acc:G5EE96])

HSP 1 Score: 189.889 bits (481), Expect = 1.794e-57
Identity = 103/283 (36.40%), Postives = 166/283 (58.66%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            ++ FGG AG +A     PLDL+K ++Q + Q G     + S     +I KN+G+ A Y+G+SA +LRQ TY+TTR G+Y  + +K   +D+P  F  KA +   AG  G  VGTP ++  +RM +D +LP+++RRNY++    L RI REEG + ++ G      RA ++ + QL+ Y Q KQ ++ + +  D +  HF +S+ +  + TV + P+D++KTR+ N        E+ G ++ F+  T   G +  +KGF P + RL PHTV+TF+  EQ+   +
Sbjct:   11 RWYFGGVAGAMAACCTHPLDLLKVQLQ-TQQQGKLTIGQLSL----KIYKNDGILAFYNGVSASVLRQLTYSTTRFGIYETV-KKQLPQDQPLPFYQKALLAGFAGACGGMVGTPGDLVNVRMQNDSKLPLEQRRNYKHALDGLVRITREEGFMKMFNGATMATSRAILMTIGQLSFYDQIKQTLISSGVAEDNLQTHFASSISAASVATVMTQPLDVMKTRMMNA----APGEFKGILDCFM-FTAKLGPMGFFKGFIPAWARLAPHTVLTFIFFEQLRLKF 282          
BLAST of slc25a-18 vs. Ensembl Celegans
Match: slc-25A10 (Oxoglutarate/malate carrier protein; SLC (SoLute Carrier) homolog [Source:UniProtKB/TrEMBL;Acc:G5EE96])

HSP 1 Score: 189.889 bits (481), Expect = 1.794e-57
Identity = 103/283 (36.40%), Postives = 166/283 (58.66%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            ++ FGG AG +A     PLDL+K ++Q + Q G     + S     +I KN+G+ A Y+G+SA +LRQ TY+TTR G+Y  + +K   +D+P  F  KA +   AG  G  VGTP ++  +RM +D +LP+++RRNY++    L RI REEG + ++ G      RA ++ + QL+ Y Q KQ ++ + +  D +  HF +S+ +  + TV + P+D++KTR+ N        E+ G ++ F+  T   G +  +KGF P + RL PHTV+TF+  EQ+   +
Sbjct:   11 RWYFGGVAGAMAACCTHPLDLLKVQLQ-TQQQGKLTIGQLSL----KIYKNDGILAFYNGVSASVLRQLTYSTTRFGIYETV-KKQLPQDQPLPFYQKALLAGFAGACGGMVGTPGDLVNVRMQNDSKLPLEQRRNYKHALDGLVRITREEGFMKMFNGATMATSRAILMTIGQLSFYDQIKQTLISSGVAEDNLQTHFASSISAASVATVMTQPLDVMKTRMMNA----APGEFKGILDCFM-FTAKLGPMGFFKGFIPAWARLAPHTVLTFIFFEQLRLKF 282          
BLAST of slc25a-18 vs. Ensembl Celegans
Match: ucp-4 (UnCoupling Protein (Mitochondrial substrate carrier) [Source:UniProtKB/TrEMBL;Acc:O01883])

HSP 1 Score: 129.413 bits (324), Expect = 3.631e-34
Identity = 82/294 (27.89%), Postives = 147/294 (50.00%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAY-KSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGI--GMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRR-NYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQN----------MTVVN-GVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            K+    +A ++A     PLD+ K R+Q++    +K    + ++D I++    EG  A+++G++  + R   YT  R+G Y  +     +K+   SF     +  G  +GLI  F  +PT++  ++M  +G   + K+   Y         + R +G   LW G +P   RAA++N+A +A+Y   K  +++     D    H  AS  +G    + S+P D+VKTR+ +          M   N  V  Y G ++ +I+I K+EG  SL+KGF P ++R+ P ++  +V  E++
Sbjct:   26 KYFLSCTAALVAETVTYPLDITKTRLQIARNKFTKGGMVQVTYDIIRR----EGAMALWTGVAPAITRHYIYTGIRMGAYEQIRLLTFNKEVEKSFPLWKSMLCGAFSGLIAQFAASPTDLVKVQMQMEGLRRLQKQPLRYTGATDCFRSLYRTQGFFGLWIGWMPNCQRAALLNMADIATYDSVKHGLIDNFELKDNWLTHAVASACAGLAAAIVSLPSDVVKTRMMDQIRHELDAKMMHKKNTHVDLYKGVVDCYIKIIKNEGFFSLYKGFLPSYIRMAPWSLTFWVSYEEI 315          

HSP 2 Score: 69.707 bits (169), Expect = 4.461e-13
Identity = 55/205 (26.83%), Postives = 91/205 (44.39%), Query Frame = 3
Query:  132 SIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA---YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTA----LFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMD----KRRN-----YRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQ 698
            S P +     G  +G+IA     P DLVK +MQM G    +K    Y  + D  + + + +G F ++ G      R A      +  Y +    L + F  KD   +++T A     AGL  + V  P++V   RM    R  +D     ++N     Y+ V     +I++ EG  +L++G LP+  R A  +L    SY + ++
Sbjct:  116 SFPLWKSMLCGAFSGLIAQFAASPTDLVKVQMQMEGLRRLQKQPLRYTGATDCFRSLYRTQGFFGLWIGWMPNCQRAALLNMADIATYDSVKHGLIDNFELKD---NWLTHAVASACAGLAAAIVSLPSDVVKTRMMDQIRHELDAKMMHKKNTHVDLYKGVVDCYIKIIKNEGFFSLYKGFLPSYIRMAPWSLTFWVSYEEIRK 317          
BLAST of slc25a-18 vs. Ensembl Fly
Match: CG1907 (gene:FBgn0039674 transcript:FBtr0085447)

HSP 1 Score: 346.28 bits (887), Expect = 3.985e-118
Identity = 167/290 (57.59%), Postives = 206/290 (71.03%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSK-DKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETEL-FNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKN 1004
            N +KF FGG +GM AT+ VQPLDLVK RMQ+SG    KK Y+SS   I+ I   EG  A+Y G+ A LLRQATYTT RLG+YT L + F  K  + P       +G  AG  G+F+GTP EVAL+RMTSDGRLP+ +RRNY NV +ALARI REEG+ ALWRG LPT+GRA VVN+ QLASYSQ K       L   +GI +HF ASM+SG +TT+ SMP+DI KTRIQNM +V+G  EY G  +  +R+ + EGV +LWKGFTPY+ RLGPHTV+TF++LEQ+N  Y  
Sbjct:   17 NAIKFLFGGLSGMGATMVVQPLDLVKTRMQISGAGSGKKEYRSSLHCIQTIVSKEGPLALYQGIGAALLRQATYTTGRLGMYTYLNDLFREKFQRSPGITDSMAMGTIAGACGAFIGTPAEVALVRMTSDGRLPVAERRNYTNVANALARITREEGLTALWRGSLPTVGRAMVVNMTQLASYSQFKTYFRHGPLQMEEGIKLHFCASMLSGLLTTITSMPLDIAKTRIQNMKMVDGKPEYRGTADVLLRVARQEGVFALWKGFTPYYCRLGPHTVLTFIILEQLNQGYNK 306          
BLAST of slc25a-18 vs. Ensembl Fly
Match: CG18418 (gene:FBgn0035568 transcript:FBtr0073366)

HSP 1 Score: 325.094 bits (832), Expect = 6.923e-110
Identity = 151/290 (52.07%), Postives = 210/290 (72.41%), Query Frame = 3
Query:  132 SIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSK-DKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            ++P ++KF  GG++GM+AT  VQPLDL+K RMQ+SG  G+++ YK+SF+ + ++ KNEG+ ++Y+GLSAGLLRQATYT+ ++GVY    + +       PS V    +G+ AG  G+  G P EVALIRM SD RL  + RRNY+NV  A  RIV++EGV+ALWRGCLPT+GRA VVN+ QLASYS  K  +      ++GI +H  A+++SG +T+V SMP+D+ KTRIQ M V++G  EYSG I+   ++ K+EG  ++WKGFTPY +R+GPHT+ +FV LEQMN AY
Sbjct:   11 TVPTHMKFVMGGTSGMLATCIVQPLDLLKTRMQISGTLGTRE-YKNSFEVLSKVLKNEGILSLYNGLSAGLLRQATYTSAKMGVYQMELDWYRKNFGNYPSMVASMTMGIVAGAFGAMCGNPAEVALIRMMSDNRLMPEDRRNYKNVGDAFVRIVKDEGVVALWRGCLPTVGRAMVVNMVQLASYSLMKNQL--HGYLSEGIPLHLTAALVSGLLTSVTSMPLDMAKTRIQQMKVIDGKPEYSGTIDVLKKVLKNEGAFAVWKGFTPYLMRMGPHTIFSFVFLEQMNKAY 297          
BLAST of slc25a-18 vs. Ensembl Fly
Match: CG7514 (gene:FBgn0035567 transcript:FBtr0073367)

HSP 1 Score: 320.857 bits (821), Expect = 2.961e-108
Identity = 152/293 (51.88%), Postives = 204/293 (69.62%), Query Frame = 3
Query:  132 SIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSK-DKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNV 1007
            SIP Y+ +  GG AGM+ T  VQPLDLVK RMQ+S   G    YKSSFD + ++ KNEG+ A+Y+GLSAGL+RQATYTT R+G Y    + +  + + PP+ +   G+G+ AG  G+  G P EVALIRM SD RLP  +RRNY  V +A  RIV++EGV+ LW+GC+PT+GRA +VN+ QLASYSQ K    E   +  G+ +H  A+M+SG +TT+ASMP+D+ KTRIQ        AEY G ++  ++++K+EG+ SLWKGFTPY  RLGPHTV  F+ LEQ+  AYK++
Sbjct:    9 SIPGYMMYINGGLAGMLGTCIVQPLDLVKTRMQISATTGE---YKSSFDCLLKVFKNEGILALYNGLSAGLMRQATYTTARMGFYQMEIDAYRKQFNAPPTVLASMGMGILAGAFGAMFGNPAEVALIRMMSDNRLPPAERRNYTGVLNAFVRIVKDEGVITLWKGCMPTVGRAMIVNMVQLASYSQLKAAFSE---YFSGLSLHIAAAMMSGLLTTIASMPLDMAKTRIQQ----QKTAEYKGTMDVLMKVSKNEGIASLWKGFTPYLCRLGPHTVFAFIFLEQLTKAYKHI 291          
BLAST of slc25a-18 vs. Ensembl Fly
Match: Dic1 (gene:FBgn0027610 transcript:FBtr0082747)

HSP 1 Score: 194.897 bits (494), Expect = 2.012e-59
Identity = 107/283 (37.81%), Postives = 158/283 (55.83%), Query Frame = 3
Query:  159 FGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHE---GVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            FGG A + A +   PLDL+K  +Q      +++ + S    I ++ + +G+   Y+GLSA +LRQ TY+T R GVY A  +K+ + D   SF  K  +  ++GL+G  VGTP ++  +RM +D +LP  +RRNY N F  L R+ R+EG   L+ G      R  ++ + Q+A Y Q K  +L T  F D +  HF AS+++G I T  + P+D++KTR  N           G  N    I KH    G L  +KG+ P F+RLGPHT+ITFV LEQ+   +
Sbjct:   12 FGGLASVGAAMVTHPLDLIKVTLQ------TQQGHLSVAQLIPKLAREQGVLVFYNGLSASVLRQLTYSTARFGVYEA-GKKYVNTD---SFGGKVALAGASGLVGGIVGTPADMVNVRMQNDVKLPPQQRRNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIGQIAFYDQTKIYLLATPYFQDNLVTHFTASLVAGTIATTLTQPLDVLKTRSMNAK--------PGEFNGLWDIVKHTAKLGPLGFFKGYVPAFVRLGPHTIITFVFLEQLRLKF 276          
BLAST of slc25a-18 vs. Ensembl Fly
Match: Dic1 (gene:FBgn0027610 transcript:FBtr0346113)

HSP 1 Score: 194.897 bits (494), Expect = 2.012e-59
Identity = 107/283 (37.81%), Postives = 158/283 (55.83%), Query Frame = 3
Query:  159 FGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHE---GVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            FGG A + A +   PLDL+K  +Q      +++ + S    I ++ + +G+   Y+GLSA +LRQ TY+T R GVY A  +K+ + D   SF  K  +  ++GL+G  VGTP ++  +RM +D +LP  +RRNY N F  L R+ R+EG   L+ G      R  ++ + Q+A Y Q K  +L T  F D +  HF AS+++G I T  + P+D++KTR  N           G  N    I KH    G L  +KG+ P F+RLGPHT+ITFV LEQ+   +
Sbjct:   12 FGGLASVGAAMVTHPLDLIKVTLQ------TQQGHLSVAQLIPKLAREQGVLVFYNGLSASVLRQLTYSTARFGVYEA-GKKYVNTD---SFGGKVALAGASGLVGGIVGTPADMVNVRMQNDVKLPPQQRRNYNNAFDGLVRVYRQEGFKRLFSGATAATARGILMTIGQIAFYDQTKIYLLATPYFQDNLVTHFTASLVAGTIATTLTQPLDVLKTRSMNAK--------PGEFNGLWDIVKHTAKLGPLGFFKGYVPAFVRLGPHTIITFVFLEQLRLKF 276          
BLAST of slc25a-18 vs. Ensembl Zebrafish
Match: slc25a11 (solute carrier family 25 member 11 [Source:ZFIN;Acc:ZDB-GENE-040625-79])

HSP 1 Score: 403.29 bits (1035), Expect = 1.937e-140
Identity = 190/289 (65.74%), Postives = 226/289 (78.20%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYK 1001
            P  +KF FGG AGM AT+FVQPLDLVKNRMQ+SGQ    + YK+SF A+  I +NEG+  IY+GLSAGLLRQATYTTTRLG+YT LFE+ S  D  PP+F  KA IGM+AG  G+FVGTP EVALIRMT+DGRLP D+RR Y NVF+AL RI REEGV  LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F D I  HF ASMISG +TT ASMPVDIVKTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN  YK
Sbjct:   14 PKSIKFLFGGLAGMGATVFVQPLDLVKNRMQLSGQGSKAREYKTSFHAVGSILRNEGVRGIYTGLSAGLLRQATYTTTRLGIYTILFERMSKADGTPPNFFMKALIGMTAGATGAFVGTPAEVALIRMTADGRLPPDQRRGYTNVFNALVRITREEGVTTLWRGCIPTMARAVVVNAAQLASYSQSKQALLDSGYFRDDILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGLDVLVKVIRNEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKFYK 302          
BLAST of slc25a-18 vs. Ensembl Zebrafish
Match: slc25a14 (solute carrier family 25 member 14 [Source:ZFIN;Acc:ZDB-GENE-040426-749])

HSP 1 Score: 188.348 bits (477), Expect = 9.016e-57
Identity = 101/284 (35.56%), Postives = 158/284 (55.63%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKR-RNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            N+  F +GG A ++A     P+DL K R+Q+ GQ    +  Y+  F A+ +I + EG+ A+YSG+S  LLRQA+Y T ++G Y  L + F S  +  + V     G+ +G++ S +  PT+V  IRM + G L       N+ N++         EG   LWRG +PT  RAA+V   +L  Y   K+ ++ + L  D +  HF +S   G    +AS PVD+V+TR+ N  V+ G   Y G ++  ++  ++EG  +L+KGF P +LRLGP  +I F+  EQ+
Sbjct:    5 NWKPFVYGGMASIVAEFGTFPIDLTKTRLQVQGQTHCMEVRYRGMFHALLRIGREEGVRALYSGISPALLRQASYGTIKIGTYNTLKKLFVSHPEEETMVINVFCGVVSGVLSSSLANPTDVLKIRMQAQGSLLQGSMMSNFMNIYQT-------EGTRGLWRGVIPTAQRAAIVVGVELPVYDITKKHLIRSGLMGDTVLTHFISSFTCGLAGALASNPVDVVRTRMMNQRVLAGNPLYKGTLDGLMQTWRNEGFFALYKGFWPNWLRLGPWNIIFFMTFEQL 281          
BLAST of slc25a-18 vs. Ensembl Zebrafish
Match: slc25a14 (solute carrier family 25 member 14 [Source:ZFIN;Acc:ZDB-GENE-040426-749])

HSP 1 Score: 188.348 bits (477), Expect = 9.016e-57
Identity = 101/284 (35.56%), Postives = 158/284 (55.63%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKR-RNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            N+  F +GG A ++A     P+DL K R+Q+ GQ    +  Y+  F A+ +I + EG+ A+YSG+S  LLRQA+Y T ++G Y  L + F S  +  + V     G+ +G++ S +  PT+V  IRM + G L       N+ N++         EG   LWRG +PT  RAA+V   +L  Y   K+ ++ + L  D +  HF +S   G    +AS PVD+V+TR+ N  V+ G   Y G ++  ++  ++EG  +L+KGF P +LRLGP  +I F+  EQ+
Sbjct:    5 NWKPFVYGGMASIVAEFGTFPIDLTKTRLQVQGQTHCMEVRYRGMFHALLRIGREEGVRALYSGISPALLRQASYGTIKIGTYNTLKKLFVSHPEEETMVINVFCGVVSGVLSSSLANPTDVLKIRMQAQGSLLQGSMMSNFMNIYQT-------EGTRGLWRGVIPTAQRAAIVVGVELPVYDITKKHLIRSGLMGDTVLTHFISSFTCGLAGALASNPVDVVRTRMMNQRVLAGNPLYKGTLDGLMQTWRNEGFFALYKGFWPNWLRLGPWNIIFFMTFEQL 281          
BLAST of slc25a-18 vs. Ensembl Zebrafish
Match: ucp3 (uncoupling protein 3 [Source:ZFIN;Acc:ZDB-GENE-040426-1317])

HSP 1 Score: 186.808 bits (473), Expect = 7.055e-56
Identity = 100/294 (34.01%), Postives = 156/294 (53.06%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-----YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAH 1013
            VKF   G+A   A L   PLD  K R+Q+ G+ G+        Y+  F  I  + + EG  ++Y+GL AGL RQ ++ + R+G+Y ++ + ++   +  S VT+   G + G +      PT+V  +R  +  R   D  + Y     A   I R+EGV  LW+GC+P + R A+VN A+L +Y   K +IL+ +L  D +  HF A+  +GF TT+ + PVD+VKTR  N    +   +Y  A+N  + +   EG  + +KGF P FLRLG   ++ FV  EQ+      + H
Sbjct:   15 VKFFGAGTAACFADLVTFPLDTAKVRLQIQGESGTAPGSAVLKYRGVFGTITTMVRTEGARSLYNGLVAGLQRQMSFASVRIGLYDSMKQFYTRGSENASIVTRLLAGCTTGAMAVAFAQPTDVVKVRFQAQVR-HTDGGKRYNGTMDAYRTIARDEGVRGLWKGCMPNITRNAIVNCAELVTYDIIKDLILKYDLMTDNLPCHFTAAFGAGFCTTIVASPVDVVKTRFMN----SSAGQYGSALNCALMMLTKEGPAAFYKGFMPSFLRLGSWNIVMFVSYEQIKRCMTRMQH 303          
BLAST of slc25a-18 vs. Ensembl Zebrafish
Match: slc25a14 (solute carrier family 25 member 14 [Source:ZFIN;Acc:ZDB-GENE-040426-749])

HSP 1 Score: 182.185 bits (461), Expect = 3.815e-54
Identity = 98/276 (35.51%), Postives = 153/276 (55.43%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKR-RNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVI 962
            N+  F +GG A ++A     P+DL K R+Q+ GQ    +  Y+  F A+ +I + EG+ A+YSG+S  LLRQA+Y T ++G Y  L + F S  +  + V     G+ +G++ S +  PT+V  IRM + G L       N+ N++         EG   LWRG +PT  RAA+V   +L  Y   K+ ++ + L  D +  HF +S   G    +AS PVD+V+TR+ N  V+ G   Y G ++  ++  ++EG  +L+KGF P +LRLGP  +I
Sbjct:    5 NWKPFVYGGMASIVAEFGTFPIDLTKTRLQVQGQTHCMEVRYRGMFHALLRIGREEGVRALYSGISPALLRQASYGTIKIGTYNTLKKLFVSHPEEETMVINVFCGVVSGVLSSSLANPTDVLKIRMQAQGSLLQGSMMSNFMNIYQT-------EGTRGLWRGVIPTAQRAAIVVGVELPVYDITKKHLIRSGLMGDTVLTHFISSFTCGLAGALASNPVDVVRTRMMNQRVLAGNPLYKGTLDGLMQTWRNEGFFALYKGFWPNWLRLGPWNII 273          
BLAST of slc25a-18 vs. Ensembl Xenopus
Match: slc25a11 (solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 [Source:NCBI gene;Acc:595075])

HSP 1 Score: 407.142 bits (1045), Expect = 1.313e-140
Identity = 190/290 (65.52%), Postives = 228/290 (78.62%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKN 1004
            P  VKF FGG AGM AT+FVQPLDLVKNRMQ+SG+    K YK+SF A+  I +NEGL  IY+GLSAGLLRQATYTTTRLG+YT LFEKF+  D  PP+F+ KA IGM+AG  G+FVGTP EVALIRMT+DGR+P+D+RR Y NVF+AL R+ REEG+  LWRGC+PTM RA VVN AQLASYSQ+KQ +L+T  F D I  HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN  YK 
Sbjct:   95 PKAVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTKEYKTSFHAVGSILRNEGLRGIYTGLSAGLLRQATYTTTRLGIYTILFEKFTKADGTPPNFLMKAAIGMTAGATGAFVGTPAEVALIRMTADGRMPVDQRRGYTNVFNALVRMSREEGITTLWRGCVPTMARAVVVNAAQLASYSQSKQFLLDTGYFGDDILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLVKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKYYKK 384          
BLAST of slc25a-18 vs. Ensembl Xenopus
Match: slc25a11 (solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 [Source:NCBI gene;Acc:595075])

HSP 1 Score: 390.963 bits (1003), Expect = 1.906e-135
Identity = 181/277 (65.34%), Postives = 219/277 (79.06%), Query Frame = 3
Query:  177 MIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKN 1004
            M AT+FVQPLDLVKNRMQ+SG+    K YK+SF A+  I +NEGL  IY+GLSAGLLRQATYTTTRLG+YT LFEKF+  D  PP+F+ KA IGM+AG  G+FVGTP EVALIRMT+DGR+P+D+RR Y NVF+AL R+ REEG+  LWRGC+PTM RA VVN AQLASYSQ+KQ +L+T  F D I  HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN  YK 
Sbjct:   34 MGATVFVQPLDLVKNRMQLSGEGAKTKEYKTSFHAVGSILRNEGLRGIYTGLSAGLLRQATYTTTRLGIYTILFEKFTKADGTPPNFLMKAAIGMTAGATGAFVGTPAEVALIRMTADGRMPVDQRRGYTNVFNALVRMSREEGITTLWRGCVPTMARAVVVNAAQLASYSQSKQFLLDTGYFGDDILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLVKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKYYKK 310          
BLAST of slc25a-18 vs. Ensembl Xenopus
Match: slc25a11 (solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 [Source:NCBI gene;Acc:595075])

HSP 1 Score: 352.058 bits (902), Expect = 1.800e-120
Identity = 173/290 (59.66%), Postives = 207/290 (71.38%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKN 1004
            P  VKF FGG AGM AT+FVQPLDLVKNRMQ+SG+    K YK+SF A+  I +NEGL  IY+GLSAGLLRQATYTTTRLG+YT LFEKF+  D  PP+F+ KA IGM+AG  G+FVGTP EVALIRMT+DGR+P+D+RR Y NVF+AL R+ REEG+  LWR  L   GRA      Q                F D I  HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN  YK 
Sbjct:   11 PKAVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTKEYKTSFHAVGSILRNEGLRGIYTGLSAGLLRQATYTTTRLGIYTILFEKFTKADGTPPNFLMKAAIGMTAGATGAFVGTPAEVALIRMTADGRMPVDQRRGYTNVFNALVRMSREEGITTLWRVTLA--GRAGTACDTQW--------------YFGDDILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLVKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKYYKK 284          
BLAST of slc25a-18 vs. Ensembl Xenopus
Match: slc25a11 (solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 [Source:NCBI gene;Acc:595075])

HSP 1 Score: 330.487 bits (846), Expect = 1.630e-112
Identity = 152/233 (65.24%), Postives = 184/233 (78.97%), Query Frame = 3
Query:  309 LFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKN 1004
            LF   +GLSAGLLRQATYTTTRLG+YT LFEKF+  D  PP+F+ KA IGM+AG  G+FVGTP EVALIRMT+DGR+P+D+RR Y NVF+AL R+ REEG+  LWRGC+PTM RA VVN AQLASYSQ+KQ +L+T  F D I  HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN  YK 
Sbjct:   13 LFGGLAGLSAGLLRQATYTTTRLGIYTILFEKFTKADGTPPNFLMKAAIGMTAGATGAFVGTPAEVALIRMTADGRMPVDQRRGYTNVFNALVRMSREEGITTLWRGCVPTMARAVVVNAAQLASYSQSKQFLLDTGYFGDDILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLVKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKYYKK 245          
BLAST of slc25a-18 vs. Ensembl Xenopus
Match: ucp2 (uncoupling protein 2 (mitochondrial, proton carrier) [Source:NCBI gene;Acc:394786])

HSP 1 Score: 183.341 bits (464), Expect = 2.504e-54
Identity = 100/287 (34.84%), Postives = 154/287 (53.66%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDG----SKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTA 995
            VKF   G+A  IA LF  PLD  K R+Q+ G++         YK  F  I  + K EG  ++Y+GL AGL RQ ++ + R+G+Y ++ + ++   +     ++   G + G +   V  PT+V  +R  +      ++R  Y+   HA   I REEG+  LW+G  P + R A+VN  +L +Y   K  +L+  +  D +  HF ++  +GF TTV + PVD+VKTR  N    +   +Y+ AIN  I + + EG  + +KGF P FLRLG   V+ FV  EQ+  A
Sbjct:   15 VKFVGAGTAACIADLFTFPLDTAKVRLQIQGENKVVNVKAAQYKGVFGTISTMVKTEGPKSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHVGIGSRLAAGCTTGAMAVAVAQPTDVVKVRFQAQANSSANRR--YKGTMHAYRTIAREEGMRGLWKGTAPNITRNAIVNCTELVTYDIIKDSLLKANIMTDNLPCHFTSAFGAGFCTTVIASPVDVVKTRYMN----SAKGQYASAINCAITMFRKEGPKAFYKGFMPSFLRLGSWNVVMFVTYEQLKRA 295          

HSP 2 Score: 68.9366 bits (167), Expect = 1.902e-12
Identity = 45/193 (23.32%), Postives = 81/193 (41.97%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYT----ALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETE 716
            + A G + G +A    QP D+VK R Q      + + YK +  A + I + EG+  ++ G +  + R A    T L  Y     +L +     D  P   T A     AG   + + +P +V   R  +  +        Y +  +    + R+EG  A ++G +P+  R    N+    +Y Q K+ ++  +
Sbjct:  117 RLAAGCTTGAMAVAVAQPTDVVKVRFQAQANSSANRRYKGTMHAYRTIAREEGMRGLWKGTAPNITRNAIVNCTELVTYDIIKDSLLKANIMTDNLPCHFTSA---FGAGFCTTVIASPVDVVKTRYMNSAK------GQYASAINCAITMFRKEGPKAFYKGFMPSFLRLGSWNVVMFVTYEQLKRAMMSAQ 300          
BLAST of slc25a-18 vs. Ensembl Mouse
Match: Slc25a11 (solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 [Source:MGI Symbol;Acc:MGI:1915113])

HSP 1 Score: 407.527 bits (1046), Expect = 4.488e-142
Identity = 191/291 (65.64%), Postives = 229/291 (78.69%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNV 1007
            P  VKF FGG AGM AT+FVQPLDLVKNRMQ+SG+    + YK+SF A+  I K EGL  IY+GLSAGLLRQATYTTTRLG+YT LFE+ +  D  PP F+ KA IGM+AG  G+FVGTP EVALIRMT+DGRLP D+RR Y+NVF+AL RI REEGV  LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F+D I  HF ASMISG +TT ASMPVDIVKTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN AYK +
Sbjct:   20 PKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKTEGLKGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGLDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310          
BLAST of slc25a-18 vs. Ensembl Mouse
Match: Slc25a11 (solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11 [Source:MGI Symbol;Acc:MGI:1915113])

HSP 1 Score: 270.011 bits (689), Expect = 9.266e-90
Identity = 129/193 (66.84%), Postives = 152/193 (78.76%), Query Frame = 3
Query:  177 MIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGA 752
            M AT+FVQPLDLVKNRMQ+SG+    + YK+SF A+  I K EGL  IY+GLSAGLLRQATYTTTRLG+YT LFE+ +  D  PP F+ KA IGM+AG  G+FVGTP EVALIRMT+DGRLP D+RR Y+NVF+AL RI REEGV  LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F+D I  HF A
Sbjct:    1 MGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKTEGLKGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCA 193          

HSP 2 Score: 51.9878 bits (123), Expect = 2.299e-7
Identity = 33/134 (24.63%), Postives = 55/134 (41.04%), Query Frame = 3
Query:  546 KRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRI--QNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLR 941
            K R Y+  FHAL  I++ EG+  ++ G    + R A     +L  Y+   + +   +    G  +     M +G        P ++   R+        +    Y    NA +RI + EGV +LW+G  P   R
Sbjct:   25 KTREYKTSFHALTSILKTEGLKGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWRGCIPTMAR 158          
BLAST of slc25a-18 vs. Ensembl Mouse
Match: Slc25a14 (solute carrier family 25 (mitochondrial carrier, brain), member 14 [Source:MGI Symbol;Acc:MGI:1330823])

HSP 1 Score: 187.578 bits (475), Expect = 2.304e-56
Identity = 101/288 (35.07%), Postives = 161/288 (55.90%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKK----AYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNM-TVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMN 989
            N+  F +GG A ++A     P+DL K R+Q+ GQ    +     Y+  F A+ +I K EG+ A+YSG++  LLRQA+Y T ++G+Y +L   F  + +  + +     G+ +G+I S +  PT+V  IRM + G L         ++  +   I ++EG   LWRG +PT  RAA+V   +L  Y   K+ ++ + +  D I  HF +S   G    +AS PVD+V+TR+ N   +V  V  Y G ++  +++ KHEG  +L+KGF P +LRLGP  +I F+  EQ+ 
Sbjct:    5 NWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQG------SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLIVSGMLGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 286          
BLAST of slc25a-18 vs. Ensembl Mouse
Match: Slc25a14 (solute carrier family 25 (mitochondrial carrier, brain), member 14 [Source:MGI Symbol;Acc:MGI:1330823])

HSP 1 Score: 187.578 bits (475), Expect = 5.744e-56
Identity = 101/288 (35.07%), Postives = 161/288 (55.90%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKK----AYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNM-TVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMN 989
            N+  F +GG A ++A     P+DL K R+Q+ GQ    +     Y+  F A+ +I K EG+ A+YSG++  LLRQA+Y T ++G+Y +L   F  + +  + +     G+ +G+I S +  PT+V  IRM + G L         ++  +   I ++EG   LWRG +PT  RAA+V   +L  Y   K+ ++ + +  D I  HF +S   G    +AS PVD+V+TR+ N   +V  V  Y G ++  +++ KHEG  +L+KGF P +LRLGP  +I F+  EQ+ 
Sbjct:   37 NWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQG------SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLIVSGMLGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 318          
BLAST of slc25a-18 vs. Ensembl Mouse
Match: Slc25a14 (solute carrier family 25 (mitochondrial carrier, brain), member 14 [Source:MGI Symbol;Acc:MGI:1330823])

HSP 1 Score: 187.578 bits (475), Expect = 6.366e-56
Identity = 101/288 (35.07%), Postives = 161/288 (55.90%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKK----AYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNM-TVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMN 989
            N+  F +GG A ++A     P+DL K R+Q+ GQ    +     Y+  F A+ +I K EG+ A+YSG++  LLRQA+Y T ++G+Y +L   F  + +  + +     G+ +G+I S +  PT+V  IRM + G L         ++  +   I ++EG   LWRG +PT  RAA+V   +L  Y   K+ ++ + +  D I  HF +S   G    +AS PVD+V+TR+ N   +V  V  Y G ++  +++ KHEG  +L+KGF P +LRLGP  +I F+  EQ+ 
Sbjct:   40 NWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQG------SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLIVSGMLGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321          
BLAST of slc25a-18 vs. UniProt/SwissProt
Match: sp|Q9CR62|M2OM_MOUSE (Mitochondrial 2-oxoglutarate/malate carrier protein OS=Mus musculus OX=10090 GN=Slc25a11 PE=1 SV=3)

HSP 1 Score: 407.527 bits (1046), Expect = 3.139e-141
Identity = 191/291 (65.64%), Postives = 229/291 (78.69%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNV 1007
            P  VKF FGG AGM AT+FVQPLDLVKNRMQ+SG+    + YK+SF A+  I K EGL  IY+GLSAGLLRQATYTTTRLG+YT LFE+ +  D  PP F+ KA IGM+AG  G+FVGTP EVALIRMT+DGRLP D+RR Y+NVF+AL RI REEGV  LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F+D I  HF ASMISG +TT ASMPVDIVKTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN AYK +
Sbjct:   20 PKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKTEGLKGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGLDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310          
BLAST of slc25a-18 vs. UniProt/SwissProt
Match: sp|P90992|M2OM_CAEEL (Mitochondrial 2-oxoglutarate/malate carrier protein OS=Caenorhabditis elegans OX=6239 GN=misc-1 PE=1 SV=2)

HSP 1 Score: 406.757 bits (1044), Expect = 4.563e-141
Identity = 194/288 (67.36%), Postives = 232/288 (80.56%), Query Frame = 3
Query:  135 IPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            +PN VKFAFGG+AGM ATL VQPLDLVKNRMQ+SG  G KK Y+SS  A+  I KNEG+FA+Y+GLSAGLLRQATYTTTRLG Y  L E+F+ KDKP SF  KA +GM+AG IGSFVGTP E+ALIRMT DGRLP+++RRNY  V +AL RI +EEGVL LWRGC PT+ RA VVN AQLA+YSQAKQ +L +    DGIF HF ASMISG  TT+ASMPVDI KTRIQ+M V++G  EY  A + + ++ K+EG+ +LWKGFTPY++RLGPHTV+TF++LEQMN AY
Sbjct:    7 VPNVVKFAFGGTAGMGATLVVQPLDLVKNRMQLSGTTG-KKEYRSSMHALTSIMKNEGVFAVYNGLSAGLLRQATYTTTRLGTYAFLLERFTEKDKPLSFGMKAVLGMTAGGIGSFVGTPAEIALIRMTGDGRLPVEQRRNYTGVVNALTRITKEEGVLTLWRGCTPTVLRAMVVNAAQLATYSQAKQALLASGKVQDGIFCHFLASMISGLATTIASMPVDIAKTRIQSMKVIDGKPEYKNAFDVWGKVIKNEGIFALWKGFTPYYMRLGPHTVLTFIILEQMNAAY 293          
BLAST of slc25a-18 vs. UniProt/SwissProt
Match: sp|Q02978|M2OM_HUMAN (Mitochondrial 2-oxoglutarate/malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3)

HSP 1 Score: 406.757 bits (1044), Expect = 7.044e-141
Identity = 191/291 (65.64%), Postives = 228/291 (78.35%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNV 1007
            P  VKF FGG AGM AT+FVQPLDLVKNRMQ+SG+    + YK+SF A+  I K EGL  IY+GLSAGLLRQATYTTTRLG+YT LFE+ +  D  PP F+ KA IGM+AG  G+FVGTP EVALIRMT+DGRLP D+RR Y+NVF+AL RI REEGVL LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F+D I  HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++   ++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN AYK +
Sbjct:   20 PKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310          
BLAST of slc25a-18 vs. UniProt/SwissProt
Match: sp|P22292|M2OM_BOVIN (Mitochondrial 2-oxoglutarate/malate carrier protein OS=Bos taurus OX=9913 GN=SLC25A11 PE=1 SV=3)

HSP 1 Score: 405.216 bits (1040), Expect = 2.882e-140
Identity = 190/291 (65.29%), Postives = 231/291 (79.38%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNV 1007
            P  VKF FGG AGM AT+FVQPLDLVKNRMQ+SG+    + YK+SF A+  I + EGL  IY+GLSAGLLRQATYTTTRLG+YT LFE+ +  D  PP F+ KA IGM+AG  G+FVGTP EVALIRMT+DGRLP+D+RR Y+NVF+AL RIV+EEGV  LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F+D I  HF ASMISG +TT ASMPVDIVKTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN AYK +
Sbjct:   20 PKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALISILRAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPVDQRRGYKNVFNALFRIVQEEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGLDVLVKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310          
BLAST of slc25a-18 vs. UniProt/SwissProt
Match: sp|P97700|M2OM_RAT (Mitochondrial 2-oxoglutarate/malate carrier protein OS=Rattus norvegicus OX=10116 GN=Slc25a11 PE=1 SV=3)

HSP 1 Score: 396.741 bits (1018), Expect = 6.568e-137
Identity = 187/291 (64.26%), Postives = 225/291 (77.32%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNV 1007
            P  VKF FGG AGM AT+FVQPLDLV NRMQ+SG+    + YK+SF A+  I K EGL  IY+GLSAGLLRQATYTTTRLG+YT LFE+ +  D  PP F+ KA IGM+AG  G+FVG P EVALIRMT+DGRLP D+RR Y+NVF+AL RI REEGV  LWRGC+PTM RA VVN AQLASYSQ+KQ +L++  F+D I  HF A MISG +TT ASMPVDIVKTRIQNM +++   EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN AYK +
Sbjct:   20 PKSVKFLFGGLAGMGATVFVQPLDLVXNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGPPAEVALIRMTADGRLPADQRRGYKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCAIMISGLVTTAASMPVDIVKTRIQNMRMIDEKPEYKNGLDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310          
BLAST of slc25a-18 vs. TrEMBL
Match: A0A0H3YJ72 (Slc25a-18 OS=Schmidtea mediterranea OX=79327 GN=slc25a-18 PE=2 SV=1)

HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0
Identity = 310/310 (100.00%), Postives = 310/310 (100.00%), Query Frame = 3
Query:  123 QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAHRKVVQQQKEKEPR 1052
            QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAHRKVVQQQKEKEPR
Sbjct:    4 QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAHRKVVQQQKEKEPR 313          
BLAST of slc25a-18 vs. TrEMBL
Match: A0A2C9JGJ0 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106056063 PE=3 SV=1)

HSP 1 Score: 432.95 bits (1112), Expect = 9.337e-149
Identity = 203/285 (71.23%), Postives = 239/285 (83.86%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYK 1001
            +KF FGGSAGM AT+FVQPLDLVKNRMQ+SG  G+KK YK+SF A+  I KNEGL  IY+GLSAGLLRQATYTTTRLG+YT+LF+  S   KPP+F++KA IG++AG IG+FVGTP EVALIRMT+DGRLP+++RR Y+NVF+ALARIVREEGVL LWRGC+PT+GRA VVN AQLASYSQAKQM++ T  F DG+F+HF ASMISG ITT ASMPVDI KTRIQNM  VNG  EYSGA++   +  + EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN AY+
Sbjct:   17 IKFLFGGSAGMAATVFVQPLDLVKNRMQLSGVGGAKKQYKTSFHALSSILKNEGLSGIYTGLSAGLLRQATYTTTRLGIYTSLFDMMSRDGKPPNFISKALIGVTAGGIGAFVGTPAEVALIRMTADGRLPLEERRGYKNVFNALARIVREEGVLTLWRGCIPTVGRAMVVNAAQLASYSQAKQMLITTGYFQDGLFLHFVASMISGLITTAASMPVDIAKTRIQNMKTVNGKPEYSGAVDVLSKTIRQEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYR 301          
BLAST of slc25a-18 vs. TrEMBL
Match: H2ZMN3 (Uncharacterized protein OS=Ciona savignyi OX=51511 PE=3 SV=1)

HSP 1 Score: 431.409 bits (1108), Expect = 2.363e-148
Identity = 202/290 (69.66%), Postives = 237/290 (81.72%), Query Frame = 3
Query:  135 IPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYK 1001
            +PN VKF FGG+AGM ATLFVQPLDLVKNR+Q+SG  G +K YK+SFDAI QI +NEG+  IY+GLSAGLLRQATYTTTRLGVYT L +KFS  D  PP+F  KA +GM+AG  G+F+GTP EV+LIRMT+DGRLP D+RR Y +VF+AL+R+VREEG+  LWRGC+PTMGRA VVN AQLASYSQAKQM+L T+ F D IF HF ASMISG ITT ASMPVDI KTRIQNM  +NGV EY GAI+   ++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN  YK
Sbjct:    8 LPNGVKFLFGGTAGMGATLFVQPLDLVKNRLQLSGAGGQEKLYKNSFDAISQILRNEGIVGIYNGLSAGLLRQATYTTTRLGVYTILLDKFSDPDGTPPNFFQKAALGMTAGACGAFIGTPAEVSLIRMTADGRLPADQRRGYTSVFNALSRMVREEGLFTLWRGCIPTMGRAVVVNAAQLASYSQAKQMLLSTDYFQDNIFCHFVASMISGLITTCASMPVDIAKTRIQNMKTINGVPEYKGAIDVLGKVVRNEGFFSLWKGFTPYYFRLGPHTVLTFIFLEQMNIMYK 297          
BLAST of slc25a-18 vs. TrEMBL
Match: A0A482WDH9 (Mitochondrial 2-oxoglutarate/malate carrier protein OS=Asbolus verrucosus OX=1661398 GN=BDFB_007311 PE=3 SV=1)

HSP 1 Score: 429.098 bits (1102), Expect = 2.104e-147
Identity = 198/291 (68.04%), Postives = 241/291 (82.82%), Query Frame = 3
Query:  132 SIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKN 1004
            ++P Y+KF FGGSAGM ATLFVQPLDLVKNRMQ+SG    KK Y +SF A++ I   EGLFA+YSGLSAGLLRQATYTTTRLGVY+ LFE FS +DKPP F+TKA +GM+AG+ G+FVGTP EV+LIRMT+DGRLP ++RRNY+NVF AL R+ REEG+L LWRG +PTMGRA VVN AQLA+YSQAKQ ++ T  F+DGI +HF +SMISG +TT ASMPVDI KTRIQNM  +NG  EYSGA++  +++ K+EG+ +LWKGFTPY+ RLGPHTV+TF+ LEQMN+AY  
Sbjct:    7 TMPKYIKFLFGGSAGMGATLFVQPLDLVKNRMQLSG---VKKEYPTSFHAVRGIIAKEGLFALYSGLSAGLLRQATYTTTRLGVYSWLFETFSDEDKPPGFLTKAALGMTAGVCGAFVGTPAEVSLIRMTADGRLPANERRNYKNVFDALIRMSREEGILTLWRGAIPTMGRAMVVNAAQLATYSQAKQTLMNTGYFHDGILLHFCSSMISGLVTTAASMPVDIAKTRIQNMKTINGKPEYSGALDVLVKVIKNEGLFALWKGFTPYYFRLGPHTVLTFIFLEQMNSAYNQ 294          
BLAST of slc25a-18 vs. TrEMBL
Match: A0A1W3JQ64 (mitochondrial 2-oxoglutarate/malate carrier protein OS=Ciona intestinalis OX=7719 GN=LOC100175272 PE=3 SV=1)

HSP 1 Score: 428.713 bits (1101), Expect = 2.985e-147
Identity = 201/290 (69.31%), Postives = 240/290 (82.76%), Query Frame = 3
Query:  135 IPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYK 1001
            IP  VKF FGGSAGM ATLFVQPLDLVKNR+Q+SG  G +K YK+SFDAI +I +NEG+  IY+GLSAGLLRQATYTTTRLGVYT L +KFS KD  PP+F  KA +GM+AG  G+FVGTP EV+LIRMT+DGRLP +++R Y +VF+AL+R+V+EEG+L LWRGC+PTMGRA VVN AQLASYSQAKQM+L T+ F+D IF HF ASMISG ITT ASMPVDI KTRIQNM  +NGV EY GAI+   ++ ++EG   LWKGFTPY+ RLGPHTV+TF+ LEQMN++YK
Sbjct:    8 IPPAVKFLFGGSAGMGATLFVQPLDLVKNRLQLSGVGGQEKLYKNSFDAISKILRNEGIIGIYTGLSAGLLRQATYTTTRLGVYTILLDKFSDKDGNPPNFFKKAALGMTAGACGAFVGTPAEVSLIRMTADGRLPPEQQRGYTSVFNALSRMVQEEGILTLWRGCIPTMGRAVVVNAAQLASYSQAKQMLLSTDYFHDNIFCHFVASMISGLITTAASMPVDIAKTRIQNMKTINGVPEYKGAIDVLGKVVRNEGFFCLWKGFTPYYFRLGPHTVLTFIFLEQMNSSYK 297          
BLAST of slc25a-18 vs. Ensembl Cavefish
Match: slc25a11 (solute carrier family 25 member 11 [Source:NCBI gene;Acc:111191416])

HSP 1 Score: 402.905 bits (1034), Expect = 5.955e-140
Identity = 189/289 (65.40%), Postives = 228/289 (78.89%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYK 1001
            P  +KF FGG AGM AT+FVQPLDLVKNRMQ+SGQ    + YK+S  A+  I +NEG+  IY+GLSAGLLRQATYTTTRLG+YT LFEK +  D  PP+F  KA IGM+AG IG+FVGTP EVALIRMT+DGRLP D+RR Y NVF+AL RI REEG+  LWRGC+PTM RA VVN AQLASYSQ+KQ +++T  F+D IF+HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN  YK
Sbjct:   44 PKSIKFLFGGLAGMGATVFVQPLDLVKNRMQLSGQGSKAREYKTSLHAVASILRNEGVGGIYTGLSAGLLRQATYTTTRLGIYTVLFEKMTKADGTPPNFFMKAVIGMTAGAIGAFVGTPAEVALIRMTADGRLPPDQRRGYTNVFNALIRITREEGIPTLWRGCVPTMARAVVVNAAQLASYSQSKQALMDTGYFSDNIFLHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLLKVVRNEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNRFYK 332          
BLAST of slc25a-18 vs. Ensembl Cavefish
Match: slc25a11 (solute carrier family 25 member 11 [Source:NCBI gene;Acc:111191416])

HSP 1 Score: 329.717 bits (844), Expect = 5.895e-112
Identity = 154/232 (66.38%), Postives = 185/232 (79.74%), Query Frame = 3
Query:  309 LFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYK 1001
            LF   +GLSAGLLRQATYTTTRLG+YT LFEK +  D  PP+F  KA IGM+AG IG+FVGTP EVALIRMT+DGRLP D+RR Y NVF+AL RI REEG+  LWRGC+PTM RA VVN AQLASYSQ+KQ +++T  F+D IF+HF ASMISG +TT ASMPVDI KTRIQNM +++G  EY   ++  +++ ++EG  SLWKGFTPY+ RLGPHTV+TF+ LEQMN  YK
Sbjct:   50 LFGGLAGLSAGLLRQATYTTTRLGIYTVLFEKMTKADGTPPNFFMKAVIGMTAGAIGAFVGTPAEVALIRMTADGRLPPDQRRGYTNVFNALIRITREEGIPTLWRGCVPTMARAVVVNAAQLASYSQSKQALMDTGYFSDNIFLHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLLKVVRNEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNRFYK 281          
BLAST of slc25a-18 vs. Ensembl Cavefish
Match: ucp3 (mitochondrial uncoupling protein 2-like [Source:NCBI gene;Acc:103026990])

HSP 1 Score: 188.734 bits (478), Expect = 1.121e-56
Identity = 102/288 (35.42%), Postives = 157/288 (54.51%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-----YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTA 995
            VKF   G+A  IA L   PLD  K R+Q+ G+    +      Y+  F  I  + + EG  ++Y+GL AGL RQ ++ + R+G+Y ++ + ++   +  S V++   G + G +      PT+V  +R  +  R+  D  + Y +   A   I R EG+  LW+GCLP + R A+VN A+L +Y   K++IL+  L  D +  HF A+  +GF TT+ + PVD+VKTR  N    +   +YS AIN  I +   EG  + +KGF P FLRLG   ++ FV  EQ+  A
Sbjct:   15 VKFFGAGTAACIADLVTFPLDTAKVRLQIQGESKPAEGVAGTKYRGVFGTINTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSMKQFYTRGSEEASIVSRLMAGCTTGAMAVAFAQPTDVVKVRFQAQVRV-ADGAKRYNSTMDAYRTIARNEGIKGLWKGCLPNITRNAIVNCAELVTYDIIKELILKYNLMTDNLPCHFTAAFGAGFCTTIVASPVDVVKTRFMN----SSPGQYSSAINCAITMLTKEGPTAFYKGFMPSFLRLGSWNIVMFVSYEQIKRA 297          

HSP 2 Score: 68.5514 bits (166), Expect = 1.697e-12
Identity = 53/193 (27.46%), Postives = 87/193 (45.08%), Query Frame = 3
Query:  162 GGSAGMIATLFVQPLDLVKNRMQMSGQ--DGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFE---KFS-SKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRM--TSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETE 716
            G + G +A  F QP D+VK R Q   +  DG+K+ Y S+ DA + I +NEG+  ++ G    + R A      L  Y  + E   K++   D  P   T A     AG   + V +P +V   R   +S G+        Y +  +    ++ +EG  A ++G +P+  R    N+    SY Q K+ +   +
Sbjct:  122 GCTTGAMAVAFAQPTDVVKVRFQAQVRVADGAKR-YNSTMDAYRTIARNEGIKGLWKGCLPNITRNAIVNCAELVTYDIIKELILKYNLMTDNLPCHFTAA---FGAGFCTTIVASPVDVVKTRFMNSSPGQ--------YSSAINCAITMLTKEGPTAFYKGFMPSFLRLGSWNIVMFVSYEQIKRAMTRAQ 302          
BLAST of slc25a-18 vs. Ensembl Cavefish
Match: ucp3 (mitochondrial uncoupling protein 2-like [Source:NCBI gene;Acc:103026990])

HSP 1 Score: 188.734 bits (478), Expect = 1.121e-56
Identity = 102/288 (35.42%), Postives = 157/288 (54.51%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-----YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTA 995
            VKF   G+A  IA L   PLD  K R+Q+ G+    +      Y+  F  I  + + EG  ++Y+GL AGL RQ ++ + R+G+Y ++ + ++   +  S V++   G + G +      PT+V  +R  +  R+  D  + Y +   A   I R EG+  LW+GCLP + R A+VN A+L +Y   K++IL+  L  D +  HF A+  +GF TT+ + PVD+VKTR  N    +   +YS AIN  I +   EG  + +KGF P FLRLG   ++ FV  EQ+  A
Sbjct:   15 VKFFGAGTAACIADLVTFPLDTAKVRLQIQGESKPAEGVAGTKYRGVFGTINTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSMKQFYTRGSEEASIVSRLMAGCTTGAMAVAFAQPTDVVKVRFQAQVRV-ADGAKRYNSTMDAYRTIARNEGIKGLWKGCLPNITRNAIVNCAELVTYDIIKELILKYNLMTDNLPCHFTAAFGAGFCTTIVASPVDVVKTRFMN----SSPGQYSSAINCAITMLTKEGPTAFYKGFMPSFLRLGSWNIVMFVSYEQIKRA 297          

HSP 2 Score: 68.5514 bits (166), Expect = 1.697e-12
Identity = 53/193 (27.46%), Postives = 87/193 (45.08%), Query Frame = 3
Query:  162 GGSAGMIATLFVQPLDLVKNRMQMSGQ--DGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFE---KFS-SKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRM--TSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETE 716
            G + G +A  F QP D+VK R Q   +  DG+K+ Y S+ DA + I +NEG+  ++ G    + R A      L  Y  + E   K++   D  P   T A     AG   + V +P +V   R   +S G+        Y +  +    ++ +EG  A ++G +P+  R    N+    SY Q K+ +   +
Sbjct:  122 GCTTGAMAVAFAQPTDVVKVRFQAQVRVADGAKR-YNSTMDAYRTIARNEGIKGLWKGCLPNITRNAIVNCAELVTYDIIKELILKYNLMTDNLPCHFTAA---FGAGFCTTIVASPVDVVKTRFMNSSPGQ--------YSSAINCAITMLTKEGPTAFYKGFMPSFLRLGSWNIVMFVSYEQIKRAMTRAQ 302          
BLAST of slc25a-18 vs. Ensembl Cavefish
Match: ucp3 (mitochondrial uncoupling protein 2-like [Source:NCBI gene;Acc:103026990])

HSP 1 Score: 188.734 bits (478), Expect = 1.121e-56
Identity = 102/288 (35.42%), Postives = 157/288 (54.51%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-----YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTA 995
            VKF   G+A  IA L   PLD  K R+Q+ G+    +      Y+  F  I  + + EG  ++Y+GL AGL RQ ++ + R+G+Y ++ + ++   +  S V++   G + G +      PT+V  +R  +  R+  D  + Y +   A   I R EG+  LW+GCLP + R A+VN A+L +Y   K++IL+  L  D +  HF A+  +GF TT+ + PVD+VKTR  N    +   +YS AIN  I +   EG  + +KGF P FLRLG   ++ FV  EQ+  A
Sbjct:   15 VKFFGAGTAACIADLVTFPLDTAKVRLQIQGESKPAEGVAGTKYRGVFGTINTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSMKQFYTRGSEEASIVSRLMAGCTTGAMAVAFAQPTDVVKVRFQAQVRV-ADGAKRYNSTMDAYRTIARNEGIKGLWKGCLPNITRNAIVNCAELVTYDIIKELILKYNLMTDNLPCHFTAAFGAGFCTTIVASPVDVVKTRFMN----SSPGQYSSAINCAITMLTKEGPTAFYKGFMPSFLRLGSWNIVMFVSYEQIKRA 297          

HSP 2 Score: 68.5514 bits (166), Expect = 1.697e-12
Identity = 53/193 (27.46%), Postives = 87/193 (45.08%), Query Frame = 3
Query:  162 GGSAGMIATLFVQPLDLVKNRMQMSGQ--DGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFE---KFS-SKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRM--TSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETE 716
            G + G +A  F QP D+VK R Q   +  DG+K+ Y S+ DA + I +NEG+  ++ G    + R A      L  Y  + E   K++   D  P   T A     AG   + V +P +V   R   +S G+        Y +  +    ++ +EG  A ++G +P+  R    N+    SY Q K+ +   +
Sbjct:  122 GCTTGAMAVAFAQPTDVVKVRFQAQVRVADGAKR-YNSTMDAYRTIARNEGIKGLWKGCLPNITRNAIVNCAELVTYDIIKELILKYNLMTDNLPCHFTAA---FGAGFCTTIVASPVDVVKTRFMNSSPGQ--------YSSAINCAITMLTKEGPTAFYKGFMPSFLRLGSWNIVMFVSYEQIKRAMTRAQ 302          
BLAST of slc25a-18 vs. Ensembl Sea Lamprey
Match: ucp2 (uncoupling protein 2 [Source:NCBI gene;Acc:555812])

HSP 1 Score: 169.088 bits (427), Expect = 7.856e-50
Identity = 100/290 (34.48%), Postives = 157/290 (54.14%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQ----DGSKKA----YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAIN-AFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMN 989
            VKF   G+A  IA L   PLD  K R+Q+ G+    +G+ ++    Y+  F  I  + + EG  ++YSGL AGL RQ ++ + R+G+Y ++   +++  +      +   G + G +      PT+V  +R  +   + +   + Y    +A   I REEGV  LW+G  P + R A+VN A+L +Y   K  IL+ +L  D +  HF ++  +GF TTV + PVD+VKTR  N    +   +Y  A N A++ +TK EG ++ +KGF P FLRLG   V+ FV  EQ+ 
Sbjct:   15 VKFIGAGTAACIADLITFPLDTAKVRLQVQGECQRGEGAARSAGVQYRGVFGTIAAMVRTEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKNFYTNGAEHAGIGCRLLAGCTTGAMAVTFAQPTDVVKVRFQAQVNM-LGTSKRYSGTMNAYKTIAREEGVRGLWKGTGPNITRNAIVNCAELVTYDIIKDTILKYKLLTDNLPCHFVSAFGAGFCTTVVASPVDVVKTRYMN----SAPGQYRSAFNCAYLMLTK-EGAMAFYKGFVPSFLRLGSWNVVMFVTYEQLK 298          

HSP 2 Score: 70.4774 bits (171), Expect = 7.449e-14
Identity = 51/188 (27.13%), Postives = 83/188 (44.15%), Query Frame = 3
Query:  162 GGSAGMIATLFVQPLDLVKNRMQMS-GQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVY-----TALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMIL 707
            G + G +A  F QP D+VK R Q      G+ K Y  + +A K I + EG+  ++ G    + R A      L  Y     T L  K  + + P  FV+  G    AG   + V +P +V   R  +           YR+ F+    ++ +EG +A ++G +P+  R    N+    +Y Q K+ I+
Sbjct:  125 GCTTGAMAVTFAQPTDVVKVRFQAQVNMLGTSKRYSGTMNAYKTIAREEGVRGLWKGTGPNITRNAIVNCAELVTYDIIKDTILKYKLLTDNLPCHFVSAFG----AGFCTTVVASPVDVVKTRYMNSAP------GQYRSAFNCAYLMLTKEGAMAFYKGFVPSFLRLGSWNVVMFVTYEQLKRGIM 302          
BLAST of slc25a-18 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008980.1 (pep scaffold:Pmarinus_7.0:GL478832:29230:40541:-1 gene:ENSPMAG00000008118.1 transcript:ENSPMAT00000008980.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.219 bits (256), Expect = 4.542e-25
Identity = 80/269 (29.74%), Postives = 121/269 (44.98%), Query Frame = 3
Query:  195 VQPLDLVKNRMQMSGQDGS---KKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPH---TVITFVVLEQ 983
            V P+DLVK RMQ     GS   +  YK+SFD  K++ + EG+F +Y GL   LL  A     +L +   + +KF+ +DK    + +   G  AG        P E+  IR+   G +    R +  NV       +R+ G L L++G      R    +      Y+  K    + E  + G      A  I+G        P D++KTR+Q +    G   YSG I+ F +I   EG  +LWKG      R  P    T++T+ +L+Q
Sbjct:    7 VYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVVRYEGVFGLYRGLIPQLLGVAPEKAIKLTMNDLIRDKFTKRDKSIPLIGEIIAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNV-------LRDLGFLGLYKGAKACFLRDIPFSAIYFPVYAHTKSSFAD-EKGHVGPLHLLTAGAIAGMPAASLVTPADVIKTRLQ-VAARAGQTTYSGVIDCFRKILSEEGPRALWKGAGARVCRSSPQFGVTLLTYELLQQ 266          

HSP 2 Score: 56.9954 bits (136), Expect = 2.578e-9
Identity = 54/212 (25.47%), Postives = 87/212 (41.04%), Query Frame = 3
Query:  123 QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD---KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFG 749
            ++ SIP   +   GG AG    +F  PL++VK R+Q++G+  +     S+ + ++ +    G   +Y G  A  LR   ++     VY      F+ +     P   +T   I   AG+  + + TP +V   R+    R     +  Y  V     +I+ EEG  ALW+G    + R          S  Q    +L  EL      V FG
Sbjct:   83 RDKSIPLIGEIIAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-TTGPRVSALNVLRDL----GFLGLYKGAKACFLRDIPFSAIYFPVYAHTKSSFADEKGHVGPLHLLTAGAI---AGMPAASLVTPADVIKTRLQVAARA---GQTTYSGVIDCFRKILSEEGPRALWKGAGARVCR----------SSPQFGVTLLTYELLQQWFHVDFG 273          
BLAST of slc25a-18 vs. Ensembl Sea Lamprey
Match: slc25a38b (solute carrier family 25 member 38b [Source:NCBI gene;Acc:571961])

HSP 1 Score: 98.2117 bits (243), Expect = 1.006e-23
Identity = 74/276 (26.81%), Postives = 125/276 (45.29%), Query Frame = 3
Query:  162 GGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSF-DAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            G  +G  +TL +QPLDLVK R+Q+    G+ ++ +      +  + + E +  ++ GL   L+R             +L E F  +D+ PS +    +G+SA  I +    P  V   R  S        R  YR+V  AL+ I + EG+ AL+ G   T+ R A  +   +  Y+QAK M+L            F   +++G + ++ + P D +KT +Q          +S     F+ I + +G+  L+ G  P  LR    T + + V E+M
Sbjct:   12 GALSGSCSTLLLQPLDLVKTRVQLLRAAGTPRSPRVRMVSVLTHVVRTESVRGLWKGLGPSLVRCVPGVGIYFCTLHSLRESFF-RDRAPSALDSLLLGLSARTISAVCMLPVTVVKTRYESG-------RFKYRSVLGALSSIRKTEGIRALFSGLTATLARDAPFSGIYVMIYTQAKHMLLHGVEREGQAPTRFACGVLAGVVASLVTQPADTIKTYMQMEP-----HRFSHTGQTFVAICRSQGLTGLFHGAVPRCLRRTLVTAMAWTVYERM 274          
BLAST of slc25a-18 vs. Ensembl Sea Lamprey
Match: slc25a23a (solute carrier family 25 member 23a [Source:ZFIN;Acc:ZDB-GENE-121214-154])

HSP 1 Score: 85.5001 bits (210), Expect = 1.794e-18
Identity = 73/281 (25.98%), Postives = 125/281 (44.48%), Query Frame = 3
Query:  162 GGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLA--QLASYSQAKQMIL---ETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMN 989
            GG+AG ++     PLD +K  MQ+ G   SK    S     KQ+ K  G+ +++ G    +++ A  T  +   Y  + +   S +       +   G  AG     +  P EV   R+T      + K   Y  +     +I  +EGV+A ++G +P +    ++  A   LA Y   K   L     +  + GI V      +S     VAS P+ +++TR+Q    + G  + S  +  F  I K++G L L++G  P F+++ P   I++VV E + 
Sbjct:  217 GGAAGAVSRTGTAPLDRMKVFMQVHG---SKSNNISILTGFKQMIKEGGIASLWRGNGVNVIKIAPETAIKFMAYEQIKKFIGSNNVSLGIHERFMAGSLAGATAQTIIYPMEVMKTRLT------LRKTGQYSGMMDCAKKIFMKEGVIAFYKGYVPNI--IGIIPYAGIDLAIYETLKNTWLTKYAKDTADPGILVLLACGTVSSSCGQVASYPLALIRTRMQAQASMEGGPQLS-MVGLFRNIVKNDGPLGLYRGIAPNFMKVIPAVSISYVVYENLK 485          

HSP 2 Score: 57.3806 bits (137), Expect = 2.839e-9
Identity = 37/167 (22.16%), Postives = 77/167 (46.11%), Query Frame = 3
Query:  528 GRLPMDK----------RRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            G  P+D+          + N  ++     ++++E G+ +LWRG    + + A     +  +Y Q K+ I    + + GI   F A  ++G        P++++KTR+     +    +YSG ++   +I   EGV++ +KG+ P  + + P+  I   + E +   +
Sbjct:  227 GTAPLDRMKVFMQVHGSKSNNISILTGFKQMIKEGGIASLWRGNGVNVIKIAPETAIKFMAYEQIKKFIGSNNV-SLGIHERFMAGSLAGATAQTIIYPMEVMKTRL----TLRKTGQYSGMMDCAKKIFMKEGVIAFYKGYVPNIIGIIPYAGIDLAIYETLKNTW 388          

HSP 3 Score: 51.2174 bits (121), Expect = 2.341e-7
Identity = 41/178 (23.03%), Postives = 71/178 (39.89%), Query Frame = 3
Query:  123 QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQM--SGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTAL----FEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPT 638
             N+S+  + +F  G  AG  A   + P++++K R+ +  +GQ      Y    D  K+I   EG+ A Y G    ++    Y    L +Y  L      K++     P  +     G  +   G     P  +   RM +   +    + +   +F     IV+ +G L L+RG  P 
Sbjct:  298 NNVSLGIHERFMAGSLAGATAQTIIYPMEVMKTRLTLRKTGQ------YSGMMDCAKKIFMKEGVIAFYKGYVPNIIGIIPYAGIDLAIYETLKNTWLTKYAKDTADPGILVLLACGTVSSSCGQVASYPLALIRTRMQAQASMEGGPQLSMVGLFR---NIVKNDGPLGLYRGIAPN 466          
BLAST of slc25a-18 vs. Ensembl Sea Lamprey
Match: slc25a55b (solute carrier family 25 member 55b [Source:ZFIN;Acc:ZDB-GENE-040801-184])

HSP 1 Score: 79.7221 bits (195), Expect = 6.726e-17
Identity = 80/321 (24.92%), Postives = 133/321 (41.43%), Query Frame = 3
Query:  123 QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCL-PTMGRAAVVNLAQ------------------------------------------LASYSQAKQMILETELFNDGIFVH-FGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGP 950
            + IS+P   K   GG AG+I    V P+DL K R+Q   Q   ++ Y+S FD + +  ++EG+F +Y G +  L         +L     +F +F S+D K  S   +   G  AG+    V TP E+  I++   GRL   ++         L+  +   G+ +   G + P + RA V + A                                            A+ ++  ++  ET L  +  F H F +  ++G +  V+  P D+VKTR+Q++        YSG ++   RI  +EG  +  KG     L + P
Sbjct:    4 KQISLP--AKLINGGVAGLIGVTCVFPIDLAKTRLQ--NQRQGQRVYRSMFDCLVKTVRSEGVFGMYRGAAVNLALVTPEKAIKLAA-NDVFRQFLSRDGKGLSVWREMMAGCGAGVCQVVVTTPMEMLKIQLQDAGRLVAQQK---------LSANISSAGLGSAKMGAVTPVLSRAYVAHSAPPPRSAVTIARHLLHTQGLGGLYRGLGATLLRDVPFSIIYFPLFANLNELGRLACETGLEGNAPFYHSFLSGCLAGSVAAVSVSPCDVVKTRLQSLHKGASEETYSGIVDCARRIWVNEGPAAFLKGAGCRALVIAP 310          
BLAST of slc25a-18 vs. Ensembl Yeast
Match: DIC1 (Mitochondrial dicarboxylate carrier; integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix [Source:SGD;Acc:S000004340])

HSP 1 Score: 162.155 bits (409), Expect = 1.781e-47
Identity = 97/290 (33.45%), Postives = 150/290 (51.72%), Query Frame = 3
Query:  123 QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVL-ALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFN-DGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            +NI  P    + +GG+AG+ AT+   PLDL K R+Q      +     + F  ++ I  NEG+  +YSGLSA +LRQ TYTT R G Y  L E    +++  +        M +G IG   G   +V  IRM +D  L   KRRNY+N    + +I R EG L  L+ G  P M R  ++  +Q+ +Y   K  ++    F+    + H  AS+++G + T    P D++KTRI     +NG  ++  A+       + EG   +++G+ P F RLGP T++ F  +EQ+
Sbjct:   11 KNIKYP----WWYGGAAGIFATMVTHPLDLAKVRLQ-----AAPMPKPTLFRMLESILANEGVVGLYSGLSAAVLRQCTYTTVRFGAYDLLKENVIPREQLTNMAYLLPCSMFSGAIGGLAGNFADVVNIRMQNDSALEAAKRRNYKNAIDGVYKIYRYEGGLKTLFTGWKPNMVRGILMTASQVVTYDVFKNYLVTKLDFDASKNYTHLTASLLAGLVATTVCSPADVMKTRI-----MNGSGDHQPALKILADAVRKEGPSFMFRGWLPSFTRLGPFTMLIFFAIEQL 286          
BLAST of slc25a-18 vs. Ensembl Yeast
Match: OAC1 (Mitochondrial inner membrane transporter; transports oxaloacetate, sulfate, thiosulfate, and isopropylmalate; member of the mitochondrial carrier family [Source:SGD;Acc:S000001603])

HSP 1 Score: 145.206 bits (365), Expect = 9.366e-41
Identity = 90/293 (30.72%), Postives = 146/293 (49.83%), Query Frame = 3
Query:  135 IPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQ--DGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSS---KDKPPSFVTKAGI----GMSAGLIGSFVGTPTEVALIRMTSDGR-LPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQ 983
            I  +  F  GG A  IA     P++L+K RMQ+ G+    + K YK+    +  I KNEG+  +  GL+A  + Q     +RLG Y  +    +     D+ P  V   G+    G ++G+IG+ +G+P  +   R+ S    + + ++ +Y  V++ L  I + EGV  L+RG    + R    +  QL  Y+ AK ++++ +L  DG  +H  AS ISG    V   P D++ TRI N         Y G I+  ++  + EGV +L+KGF     R+ PHT++    +EQ
Sbjct:   20 ISKFGSFVAGGLAACIAVTVTNPIELIKIRMQLQGEMSASAAKVYKNPIQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRLGFYEPIRSSLNQLFFPDQEPHKVQSVGVNVFSGAASGIIGAVIGSPLFLVKTRLQSYSEFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNILVKNDLMKDGPALHLTASTISGLGVAVVMNPWDVILTRIYNQK----GDLYKGPIDCLVKTVRIEGVTALYKGFAAQVFRIAPHTIMCLTFMEQ 308          
BLAST of slc25a-18 vs. Ensembl Yeast
Match: ODC2 (Mitochondrial inner membrane transporter; 2-oxodicarboxylate transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism; ODC2 has a paralog, ODC1, that arose from the whole genome duplication [Source:SGD;Acc:S000005748])

HSP 1 Score: 109.768 bits (273), Expect = 6.782e-28
Identity = 80/304 (26.32%), Postives = 140/304 (46.05%), Query Frame = 3
Query:  135 IPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-------YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGV---YTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVN-GVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAH 1013
            +P   +F  G  AG+     + PLD+VK R Q+     +  A       Y    D +K+I K EG   +Y G+S+ +L +A    T+      Y  +F+   + ++    ++ A  G SAG+  + V  P E+  IRM        D + +Y      L + ++ EG++ L++G   TM R A+ N        Q +  +   +           A  I G + T+ + P D+VK+RIQ++  V+  V +Y+  + + + I + EG  +L+KGF P   RL P   +  VV   M   ++++ +
Sbjct:   10 LPFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIVKKEGFSRLYRGISSPMLMEAPKRATKFACNDQYQKIFKNLFNTNETTQKISIAA-GASAGMTEAAVIVPFELIKIRM-------QDVKSSYLGPMDCLKKTIKNEGIMGLYKGIESTMWRNALWNGGYFGVIYQVRNSMPVAKTKGQKTRNDLIAGAIGGTVGTMLNTPFDVVKSRIQSVDAVSSAVKKYNWCLPSLLVIYREEGFRALYKGFVPKVCRLAPGGSLMLVVFTGMMNFFRDLKY 305          
BLAST of slc25a-18 vs. Ensembl Yeast
Match: SFC1 (Mitochondrial succinate-fumarate transporter; transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization [Source:SGD;Acc:S000003856])

HSP 1 Score: 102.449 bits (254), Expect = 4.493e-25
Identity = 88/297 (29.63%), Postives = 135/297 (45.45%), Query Frame = 3
Query:  162 GGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSS--FDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVY----TALFEKFSS-KDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKR--RNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGAS---MISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGA---INAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNV 1007
            GG+AG+   L   PLD +K RMQ+  +    +  K        + I + EG  A+Y GL A ++        R   Y    T L  K S       +FV   G G++  ++   V  P EV  IR+ +    P +      Y N  HA   IV+EEGV AL+RG   T  R A    A    YS+ K+ +      +  +   +  S   +ISG I   ++ P+D +KTR+Q    ++ + + SG    I    ++ K EG  +L+KG TP  +R+ P   +TF V E +    +N+
Sbjct:   17 GGTAGLFEALCCHPLDTIKVRMQIYRRVAGIEHVKPPGFIKTGRTIYQKEGFLALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLVNKESGIVSTGNTFVAGVGAGITEAVL---VVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYTIVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFLQNYHQMD--VLPSWETSCIGLISGAIGPFSNAPLDTIKTRLQKDKSIS-LEKQSGMKKIITIGAQLLKEEGFRALYKGITPRVMRVAPGQAVTFTVYEYVREHLENL 307          
BLAST of slc25a-18 vs. Ensembl Yeast
Match: CTP1 (Mitochondrial inner membrane citrate transporter; member of the mitochondrial carrier family [Source:SGD;Acc:S000000495])

HSP 1 Score: 97.4413 bits (241), Expect = 1.973e-23
Identity = 80/287 (27.87%), Postives = 128/287 (44.60%), Query Frame = 3
Query:  153 FAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGI-GMSAGLIGSFVG-TPTEVALIRMTSDGRLPMDK-RRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILE------TELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            F  G  AG        P +  K R+Q+   D + KA ++    I +  K +G+ +IY G  A ++        R   +  + +     +      T+  I G+ AGL+ S    TP E     +  D +    K   N R V    + +VR++G   L+RG LP   R A     +L  Y++ K +I +       +  + G+    GA   SG +T  ++MP+D VKTR+Q++       +YS  +N F  I K EG+ + WKG TP   RL     I F + E++
Sbjct:   16 FLAGSLAGAAEACITYPFEFAKTRLQL--IDKASKASRNPLVLIYKTAKTQGIGSIYVGCPAFIIGNTAKAGIRFLGFDTIKDMLRDSETGELSGTRGVIAGLGAGLLESVAAVTPFEAIKTALIDDKQSATPKYHNNGRGVVRNYSSLVRDKGFSGLYRGVLPVSMRQAANQAVRLGCYNKIKTLIQDYTDSPKDKPLSSGLTFLVGA--FSGIVTVYSTMPLDTVKTRMQSLDST----KYSSTMNCFATIFKEEGLKTFWKGATPRLGRLVLSGGIVFTIYEKV 294          
BLAST of slc25a-18 vs. Ensembl Nematostella
Match: EDO47873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL59])

HSP 1 Score: 388.652 bits (997), Expect = 2.464e-135
Identity = 183/288 (63.54%), Postives = 222/288 (77.08%), Query Frame = 3
Query:  135 IPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKD-KPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTA 995
            IPNY +F  GG +GM AT FVQPLDLVKNRMQMSG  G+ K Y+SS   +  I ++EG   +Y+GLSAGLLRQATYTTTRLGVYT L + F + D   P F  K  +GM+AG IGSFVGTP E++LIRMTSDGRLP ++RR Y NVF+AL R+ +EEGVL LWRG +PT  RA VVN AQLA+YSQAKQ++L T+ F D I  HFGASMISG  TTVASMPVDI KTRIQNM +++G  EY G ++  +RI ++EGV +LWKGFTPY+ R+GPHTV+TF+ LEQ+N A
Sbjct:    8 IPNYARFVMGGLSGMGATFFVQPLDLVKNRMQMSGIGGATKEYRSSVHVVMSILRSEGFLGVYNGLSAGLLRQATYTTTRLGVYTNLLQHFKNPDGSAPGFFKKCALGMTAGAIGSFVGTPAEISLIRMTSDGRLPPEQRRGYTNVFNALYRMSKEEGVLTLWRGYIPTAVRAMVVNAAQLATYSQAKQLLLSTKYFEDNIVCHFGASMISGLATTVASMPVDIAKTRIQNMRIIDGKPEYKGTMDVLVRIVRNEGVFALWKGFTPYYFRIGPHTVLTFIFLEQLNRA 295          
BLAST of slc25a-18 vs. Ensembl Nematostella
Match: EDO34326 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPL4])

HSP 1 Score: 187.578 bits (475), Expect = 1.233e-56
Identity = 99/293 (33.79%), Postives = 164/293 (55.97%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSF----------DAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGI-GMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRI--QNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMN 989
            +F  GG + M AT    P+++VK RMQ+  + GSK   K  F            + ++ + EG+  +Y G+   LLRQA Y++TRLG Y  +     + D   + + K  + G+S+G+IGS + TPT++  IR  +   + + +   Y+N+FHA  +I ++EG L LW G  PT+ RAA ++  Q+ +Y   K ++L  EL  +G+ +H  +++++GF+ T  + PVDIV+TR   Q          Y G ++   +  +HEG+L+L+KGF P + R G  T+I F V E++ 
Sbjct:   11 RFVLGGLSCMTATTVTNPIEVVKIRMQLDNELGSKHNSKDIFRERYYKGLIRTGLSRVYREEGVRGLYRGIFPALLRQAIYSSTRLGAYEPIKNLLGATDSTSAALWKKIVAGVSSGVIGSAIATPTDLVKIRFQA---VKIGETIPYKNMFHAFYKIAKKEGFLGLWTGMKPTVKRAACISGTQIPTYDHTKHLLLNAELMREGVALHLASALVAGFVATCVASPVDIVRTRFMTQPKDTKGRPLVYQGTLDCIYKTVRHEGILALYKGFFPNWTRTGLDTIIIFFVYERLR 300          

HSP 2 Score: 65.0846 bits (157), Expect = 6.892e-12
Identity = 44/191 (23.04%), Postives = 85/191 (44.50%), Query Frame = 3
Query:  144 YVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMS------AGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQ 698
            + K   G S+G+I +    P DLVK R Q + + G    YK+ F A  +I K EG   +++G+   + R A  + T++  Y        + +     + + G+ +       AG + + V +P ++   R  +  +    +   Y+     + + VR EG+LAL++G  P   R  +  +     Y + ++
Sbjct:  117 WKKIVAGVSSGVIGSAIATPTDLVKIRFQ-AVKIGETIPYKNMFHAFYKIAKKEGFLGLWTGMKPTVKRAACISGTQIPTYDHTKHLLLNAE-----LMREGVALHLASALVAGFVATCVASPVDIVRTRFMTQPKDTKGRPLVYQGTLDCIYKTVRHEGILALYKGFFPNWTRTGLDTIIIFFVYERLRR 301          
BLAST of slc25a-18 vs. Ensembl Nematostella
Match: EDO36980 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SH35])

HSP 1 Score: 184.496 bits (467), Expect = 1.454e-55
Identity = 99/280 (35.36%), Postives = 158/280 (56.43%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMN 989
            ++  GG A  +A     PLDL+K  +Q   Q  S  +  +       + + +G+ A+Y+GL+A +LRQ TY+TTR G+Y           +P  F  K  +  ++G +G  +G P ++  +RM +D +LP+D+RRNY++VF  L +  + EGV   ++G   T  RA ++ +AQ+A Y QAKQ++L T  F D +  HF AS I+G I T  + P D++KTRI  M    G  +Y    +  +  T   G +  +KGF P ++RLGP T++T++ LEQ+ 
Sbjct:   22 RWYLGGCASAMAACCTHPLDLLKVHLQTQQQVTSGLSTMAV-----HVVRTQGVTALYNGLTASVLRQLTYSTTRYGLYEIWSGMLRKGTEPLPFYQKISLAAASGFLGGILGNPADMVNVRMQNDVKLPLDQRRNYKHVFDGLYQTAKYEGVPTWFKGVTMTSTRALLITVAQVACYDQAKQILLSTGFFKDNMVTHFTASFIAGTIATGITQPFDVMKTRI--MEARPG--QYKSVFHC-VMYTAKLGPMGFYKGFIPAWVRLGPQTILTWIFLEQLR 291          
BLAST of slc25a-18 vs. Ensembl Nematostella
Match: EDO25509 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DWA0])

HSP 1 Score: 173.326 bits (438), Expect = 4.308e-52
Identity = 84/233 (36.05%), Postives = 143/233 (61.37%), Query Frame = 3
Query:  303 EGLFAIYS-GLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            EG+  ++  GL+A +LR+ +Y++ R+G+Y  +        K  +   K   G  +G +GS +  P +V  IR+  + R+P    R Y+N FHA  +I ++EG+  L++G   T  RAA++  AQL+SY  +K M+L+T+ FND    HF +++ISGF+TT A+ PVD++KTR+ N       A Y  +++  ++  ++EG+L+L++GF P +LRLGPH + +  + EQ+  A+
Sbjct:    3 EGVLTLWKRGLAASMLREGSYSSIRMGLYDPVRTILVGDAKEVTLTNKILAGFVSGGLGSCLINPADVVKIRIQGEIRVPGQPTR-YKNTFHAFYQIWKDEGIRGLYKGVGATTLRAAILTSAQLSSYDHSKHMLLKTKYFNDDFKTHFTSALISGFVTTTATSPVDVIKTRLMNDKSTAKDALYKNSLDCLVKTIRNEGILALYRGFLPNYLRLGPHFIFSLPLYEQLRIAF 234          

HSP 2 Score: 75.8702 bits (185), Expect = 6.596e-16
Identity = 56/188 (29.79%), Postives = 88/188 (46.81%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQ-DGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTA-----LFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAK 695
            K   G  +G + +  + P D+VK R+Q   +  G    YK++F A  QI K+EG+  +Y G+ A  LR A  T+ +L  Y       L  K+ + D    F T     + +G + +   +P +V   R+ +D     D    Y+N    L + +R EG+LAL+RG LP   R     +  L  Y Q +
Sbjct:   50 KILAGFVSGGLGSCLINPADVVKIRIQGEIRVPGQPTRYKNTFHAFYQIWKDEGIRGLYKGVGATTLRAAILTSAQLSSYDHSKHMLLKTKYFNDD----FKTHFTSALISGFVTTTATSPVDVIKTRLMNDKSTAKDAL--YKNSLDCLVKTIRNEGILALYRGFLPNYLRLGPHFIFSLPLYEQLR 231          
BLAST of slc25a-18 vs. Ensembl Nematostella
Match: EDO39987 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8H5])

HSP 1 Score: 167.162 bits (422), Expect = 5.880e-49
Identity = 105/290 (36.21%), Postives = 155/290 (53.45%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQ--DGSKKA--YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQN-----MTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQ 983
            +Y  F +GG A M A L   P+D  K R+Q+ GQ  D  +KA  Y+  F A  +ITK EG+ A+++G+S  LLRQATY + +LG+Y +L        K  +       G+ AG +GS V  PT+V  IRM ++ R      +   ++  A   + R+EG+  L+RG  PT  RAAV+   +L  Y  AK+ IL+ +L  D    HF AS I+G    +AS P+D+ KTR+ N     +    G   Y  A +  +   + EG  +L++GF P F RL P  ++ F+  EQ
Sbjct:    2 DYKPFLYGGLASMTAELCTFPIDTTKTRLQLQGQVTDTKQKAIRYRGMFHAFFRITKEEGIRALFNGVSPALLRQATYGSLKLGIYHSLKRILVKDPKDETLFVNGFCGVVAGALGSAVCNPTDVLKIRMQAEYRAGAGSSKT--SMLVAFGDMYRQEGIRGLYRGVGPTSQRAAVIAGVELPVYDSAKRFILDKKLMGDHPGTHFVASAIAGLAGAIASNPIDVAKTRMMNQRNLKVKTEGGPVLYRSASHCLVVTFRTEGFFALYRGFIPNFARLCPWNIVFFMAYEQ 289          

HSP 2 Score: 58.151 bits (139), Expect = 1.574e-9
Identity = 51/182 (28.02%), Postives = 76/182 (41.76%), Query Frame = 3
Query:  171 AGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTA----LFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRN---YRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAK 695
            AG + +    P D++K RMQ   + G+  +  S   A   + + EG+  +Y G+     R A      L VY +    + +K    D P +    + I   AG I S    P +VA  RM +   L +        YR+  H L    R EG  AL+RG +P   R    N+    +Y Q K
Sbjct:  113 AGALGSAVCNPTDVLKIRMQAEYRAGAGSSKTSMLVAFGDMYRQEGIRGLYRGVGPTSQRAAVIAGVELPVYDSAKRFILDKKLMGDHPGTHFVASAIAGLAGAIAS---NPIDVAKTRMMNQRNLKVKTEGGPVLYRSASHCLVVTFRTEGFFALYRGFIPNFARLCPWNIVFFMAYEQYK 291          
BLAST of slc25a-18 vs. Ensembl Medaka
Match: ucp3 (mitochondrial uncoupling protein 2 [Source:NCBI gene;Acc:101160932])

HSP 1 Score: 195.667 bits (496), Expect = 2.404e-59
Identity = 104/287 (36.24%), Postives = 164/287 (57.14%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-------YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            VKF   G+A  IA L   PLD  K R+Q+ G+  ++KA       Y+  F  I  + + EG  ++Y+GL AGL RQ ++ + R+G+Y ++ + ++   +    VT+   G + G +      PT+V  +R  +  R  +D  R Y +  +A   I R+EG+  LWRGC+P + R A+VN A+L +Y   K++I++ +L +D +  HF A+  +GF TTV + PVD+VKTR  N    +G   YS A+N  + + K+EG  + +KGF P FLRLG   ++ FV  EQ+
Sbjct:   15 VKFFGAGTAACIADLITFPLDTAKVRLQIQGE--AQKAEGFTAVKYRGVFGTITTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSMKQFYTRGTESAGIVTRLMAGCTTGAMAVAFAQPTDVVKVRFQAQVR-QLDGERRYNSTINAYKTIARDEGIRGLWRGCMPNITRNAIVNCAELVTYDMIKELIIKYDLMSDNLPCHFTAAFGAGFCTTVVASPVDVVKTRFMN----SGSGLYSSAVNCALTMLKNEGPAAFYKGFVPSFLRLGSWNIVMFVTYEQI 294          
BLAST of slc25a-18 vs. Ensembl Medaka
Match: slc25a14 (solute carrier family 25 member 14 [Source:NCBI gene;Acc:101158716])

HSP 1 Score: 189.889 bits (481), Expect = 2.499e-57
Identity = 102/284 (35.92%), Postives = 160/284 (56.34%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKA-YKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKR-RNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            N+  F +GG A ++A     P+DL K R+Q+ GQ    +  Y+  F A+ +I K EG+ A+YSG+S  LLRQA+Y T ++G Y +L   F S+ +  + V     G+ +G++ S +  PT+V  IRM + G L       N+ N++         EG   LWRG +PT  RAA+V   +L  Y   K+ +L + +  D +  HF +S   G    +AS PVD+V+TR+ N  V++G   Y G ++  ++  ++EG  +L+KGF P +LRLGP  +I F+  EQ+
Sbjct:    5 NWKPFVYGGMASIVAEFGTFPIDLTKTRLQVQGQSQYMEVRYRGMFHALFRIGKEEGIRALYSGISPALLRQASYGTIKIGTYNSLKRLFVSRPEDETMVLNVFCGVVSGVLSSSLANPTDVLKIRMQAQGSLLQGSMMSNFINIYQT-------EGTRGLWRGVIPTAQRAAIVVGVELPVYDITKKHLLGSGVMGDTVLTHFISSFACGLAGALASNPVDVVRTRMMNQRVLSGSPTYKGTLHGVMQTWRNEGFFALYKGFWPNWLRLGPWNIIFFITFEQL 281          
BLAST of slc25a-18 vs. Ensembl Medaka
Match: slc25a10 (solute carrier family 25 member 10 [Source:NCBI gene;Acc:101168182])

HSP 1 Score: 179.874 bits (455), Expect = 1.495e-53
Identity = 107/284 (37.68%), Postives = 161/284 (56.69%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPP-SFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            ++ FGG A   A     PLDL+K  +Q + Q+  K+    +     Q+ KN+G+ A+YSGLSA L RQ +Y+ TR  +Y ++ +   +K   P  F  K  +G   G  G F+GTP ++  +RM +D +LP   RRNY++    L R+ REEG+  L+ G      R A+V + QLA Y QAKQ++L T +  D I  HF +S I+G   T    P+D++KTR+     +N   EY+G ++ F + T   G L+ +KG  P  +RL PHTV+TF+ LEQ+   +
Sbjct:    8 RWYFGGLASCGAACCTHPLDLLKVHLQ-TQQEVKKRMMGMAI----QVVKNDGVLALYSGLSASLCRQMSYSLTRFAIYESVRDLMGTKSHGPMPFYQKVLLGAFGGFTGGFIGTPADMVNVRMQNDMKLPPQHRRNYKHALDGLFRVFREEGIRRLFSGASMASSRGAMVTVGQLACYDQAKQLVLGTGVMGDNILTHFLSSFIAGGCATFLCQPLDVLKTRL-----MNSKGEYTGVLHCF-KETARLGPLAFYKGLVPAGIRLIPHTVLTFIFLEQLKKYF 280          
BLAST of slc25a-18 vs. Ensembl Medaka
Match: SLC25A30 (kidney mitochondrial carrier protein 1 [Source:NCBI gene;Acc:101158137])

HSP 1 Score: 172.94 bits (437), Expect = 6.433e-51
Identity = 96/287 (33.45%), Postives = 155/287 (54.01%), Query Frame = 3
Query:  141 NYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKK----AYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRR-NYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            N+  F FGG A + A     P+DL K R+Q+ GQ G ++     Y+    AI +I K EG  A+YSG++  +LRQA+Y T ++G Y +       + +  + +T    G+ +G+I S +  PT+V  IRM + G +       N+ N++        +EG   LW+G   T  RAA+V   +L  Y   K+ ++ +    D ++ HF +S + G    +AS PVD+V+TR+ N     G A Y G ++  ++  + EG ++L+KGF P +LRLGP  +I F+  EQ+
Sbjct:    5 NWKPFVFGGLASVTAECGTFPIDLTKTRLQVQGQVGDRRYREIRYRGMLHAIMRIGKEEGPRALYSGIAPAMLRQASYGTIKIGTYQSFKRLLVDRPEDETLLTNVACGILSGVISSSIANPTDVLKIRMQAQGNVIQGSMMGNFINIYQ-------QEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGYMGDTVYTHFLSSFVCGLAGALASNPVDVVRTRMMNQ---RGGALYQGTLDCLLQTWRSEGFMALYKGFFPNWLRLGPWNIIFFLTYEQL 281          
BLAST of slc25a-18 vs. Ensembl Medaka
Match: ENSORLT00000028230.1 (mitochondrial uncoupling protein 2 [Source:NCBI gene;Acc:101162464])

HSP 1 Score: 171.014 bits (432), Expect = 7.041e-50
Identity = 102/302 (33.77%), Postives = 155/302 (51.32%), Query Frame = 3
Query:  138 PNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQ-----DGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKR-RNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAHRKVV 1025
            P  V+    GSAG +A L   PLD  K R+Q+ G+     +G    Y+  F  I  I + EG  ++Y+GL AGL RQ T+ + R+G+Y ++ + ++         T+   G + G +      PT+V  +R  +  RL      + Y +   A   IVR+EG+  LW+G LP + R A VN ++L +Y   K+++L+  L  D +  HF A+  +G  TTV + PVD+VKTR  N   V G  +Y GA+N    +   EG  + +KGF P FLRL    ++ FV  EQ    +  +   KV 
Sbjct:    7 PAAVRVFAAGSAGCVADLVTFPLDTAKVRLQIQGEGRTSLEGQTVKYRGVFGTIVTIVRTEGPRSLYNGLVAGLQRQMTFASVRIGLYDSMKQLYAGSADNAGLGTRLLAGCTTGAMAVAFAQPTDVVKVRFQAQVRLLESATGKRYSSTTQAYRTIVRDEGLRGLWKGALPNIIRNATVNCSELVTYDVIKELLLKNHLMTDNMPCHFIAAFSAGLCTTVVASPVDVVKTRYMNS--VPG--QYGGALNCAATMLIKEGPTAFYKGFMPSFLRLLSWNIVMFVSYEQFKRGFLRLHRNKVC 304          
BLAST of slc25a-18 vs. Planmine SMEST
Match: SMESG000019229.1 (SMESG000019229.1)

HSP 1 Score: 639.417 bits (1648), Expect = 0.000e+0
Identity = 308/310 (99.35%), Postives = 310/310 (100.00%), Query Frame = 3
Query:  123 QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAHRKVVQQQKEKEPR 1052
            QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQIT+NEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMD+RRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAHRKVVQQQKEKEPR
Sbjct:    4 QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITRNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDQRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAHRKVVQQQKEKEPR 313          
BLAST of slc25a-18 vs. Planmine SMEST
Match: SMESG000073400.1 (SMESG000073400.1)

HSP 1 Score: 402.519 bits (1033), Expect = 1.853e-140
Identity = 184/298 (61.74%), Postives = 236/298 (79.19%), Query Frame = 3
Query:  123 QNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAHR 1016
            Q+I IP+Y+KFA GGS+G++ TL +QPLD+VK RMQ+SGQDG +K+YKSSFDAI +IT NEG+ AIYSGLSA L RQATYTT RLG+YT L+E++SSK+  P+   K  I + AGL+GSFVGTP E+ALIRMT+DG  P++++RNYRNVFHAL  I+ ++G L LW+  LPTM R  VVN  QLASYSQ KQ+++ET+  +DGI +HF ASMISG  T V SMPVDI+KTRIQNM ++NG+ EYS   N F RI K+EGV SLWKGF PYFL++G +TVI F++ EQM+ AY+ + ++
Sbjct:    4 QSIPIPDYIKFAIGGSSGILTTLIIQPLDVVKTRMQISGQDGYQKSYKSSFDAIYRITTNEGILAIYSGLSAALFRQATYTTARLGIYTTLYERYSSKNHHPNLAIKLFIAIIAGLVGSFVGTPAEIALIRMTADGIFPIEQKRNYRNVFHALGCIIEDDGFLGLWKTVLPTMCRGVVVNFIQLASYSQIKQILIETKSLSDGILLHFLASMISGLNTAVLSMPVDIIKTRIQNMRIINGIPEYSSCWNVFYRIFKNEGVHSLWKGFLPYFLKIGSNTVIMFIIFEQMSEAYRVLVYQ 301          
BLAST of slc25a-18 vs. Planmine SMEST
Match: SMESG000046675.1 (SMESG000046675.1)

HSP 1 Score: 191.815 bits (486), Expect = 3.694e-58
Identity = 117/295 (39.66%), Postives = 163/295 (55.25%), Query Frame = 3
Query:  123 QNISIPNYVKF-AFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQ--MNTAY 998
            +N+S  + V +  FGG A  +A     PLDL+K  +Q       KK +      +K + KN+G+ A+Y+GLSA LLRQ TY+ TR G+Y   ++K    + P  F  KA + M AG IG  VG P ++  +RM +D ++  + RRNY N F  + R+V+EEGVL L+ G   T  RA  +   QLA Y   KQ +++T  F+D I  HF AS  +  I T+ + P D++KTR+ N         YSG       I K  G L  +KG  P F+RLGP TV+TF+ LEQ  MN  Y
Sbjct:    4 KNLSKKDKVGYWYFGGVASAMAAACTHPLDLLKVHLQTQ----QKKEFGMGGMFLK-VVKNDGILALYNGLSASLLRQLTYSMTRFGIYET-YKKKKGANLP--FYEKAAVSMVAGFIGGIVGNPADMVNVRMQNDMKIAKELRRNYNNAFDGMFRVVKEEGVLVLFSGVSMTATRACFMTFGQLAFYDLFKQTLMQTGFFSDNILTHFTASTGAAGIATLMTQPFDVMKTRLMNAK----PGAYSGLAACGADIMK-TGPLGFFKGLVPAFIRLGPQTVLTFIFLEQLRMNLGY 285          
BLAST of slc25a-18 vs. Planmine SMEST
Match: SMESG000062675.1 (SMESG000062675.1)

HSP 1 Score: 162.925 bits (411), Expect = 3.469e-47
Identity = 91/286 (31.82%), Postives = 151/286 (52.80%), Query Frame = 3
Query:  150 KFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIK---QITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAY 998
            ++ FGG +  +A     PLDL+K  +Q           K  F  ++    + K++G  A+YSG+SA  +RQ  Y+  R G+Y  +++    K K      +  +   AGL+G  +G P +V  +RM +D +LP+D+RRNY +VF    ++++ EG   L  G   T  RA ++ + Q   Y + K M+L+T  F D    HF A++ +   T   + P+D++KTR+ N+       +Y G ++ F  I K  G L+ +KG  P F+R+ PH VI  ++ EQ+ T +
Sbjct:   10 RWYFGGLSSALAISATHPLDLIKVHLQTQQ--------KKEFGFLRMGMNVIKHDGFLALYSGISASFIRQIFYSFPRFGIY-EIYKNNLDKSKKIKLYEQIAVSGFAGLVGGVIGNPFDVLNVRMQNDVKLPLDQRRNYNHVFDGFFKVIKSEGFPGLMNGVSMTASRAVLMTIGQTTVYDRCKFMLLKTVFFVDDPITHFTAAIGAALSTIFLANPLDVMKTRLMNVP----PGKYDGIVSCFKDIVK-TGPLAFYKGLLPAFIRICPHFVILHLIREQLTTNF 281          
BLAST of slc25a-18 vs. Planmine SMEST
Match: SMESG000020904.1 (SMESG000020904.1)

HSP 1 Score: 151.754 bits (382), Expect = 6.909e-43
Identity = 98/284 (34.51%), Postives = 149/284 (52.46%), Query Frame = 3
Query:  147 VKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAYKSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSSKDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYRNVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILETELFNDGIFVH----FGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGAINAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQM 986
            VK+ +GG +  +A     PLDL K  +Q S     K   K        + KN+G+  +Y+GLSA +LRQ TY+  R G++   ++   SK +  S V         G IG   G P +   +RM +D +LP   RRNY++ FH L ++ + EG   L+ G   T  RA ++ + Q A Y Q K ++L T LF+D    H    FGA+ I+ F+T     P D++KTR+ N      V +Y+G  +    I  + G L  +KG  P F+R+GPHT++ F++ EQ+
Sbjct:   13 VKWYYGGVSSTLAIGATHPLDLAKVHLQTS-----KTQSKGLISVFVNVIKNDGVLGLYNGLSASILRQITYSFPRFGLHD-WYKNTVSKKRKVSVVENVMAAGFGGAIGGITGNPADTINVRMQNDMKLPEASRRNYKSAFHGLFQVFKNEGFKGLFSGVTMTTNRAILMTIGQGAGYDQMKLILLSTNLFDDNPATHILSAFGAAGIATFLT----QPFDVMKTRLMNAQ----VGQYTGLGHCAKDILLN-GPLGFFKGIVPAFVRIGPHTILLFIIKEQL 281          
The following BLAST results are available for this feature:
BLAST of slc25a-18 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SLC25A111.467e-14165.64solute carrier family 25 member 11 [Source:HGNC Sy... [more]
SLC25A111.083e-13465.47solute carrier family 25 member 11 [Source:HGNC Sy... [more]
SLC25A114.664e-11365.81solute carrier family 25 member 11 [Source:HGNC Sy... [more]
SLC25A102.979e-5837.19solute carrier family 25 member 10 [Source:HGNC Sy... [more]
SLC25A141.256e-5635.07solute carrier family 25 member 14 [Source:HGNC Sy... [more]
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BLAST of slc25a-18 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
misc-13.587e-14267.36Mitochondrial 2-oxoglutarate/malate carrier protei... [more]
misc-13.587e-14267.36Mitochondrial 2-oxoglutarate/malate carrier protei... [more]
slc-25A101.794e-5736.40Oxoglutarate/malate carrier protein; SLC (SoLute C... [more]
slc-25A101.794e-5736.40Oxoglutarate/malate carrier protein; SLC (SoLute C... [more]
ucp-43.631e-3427.89UnCoupling Protein (Mitochondrial substrate carrie... [more]
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BLAST of slc25a-18 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG19073.985e-11857.59gene:FBgn0039674 transcript:FBtr0085447[more]
CG184186.923e-11052.07gene:FBgn0035568 transcript:FBtr0073366[more]
CG75142.961e-10851.88gene:FBgn0035567 transcript:FBtr0073367[more]
Dic12.012e-5937.81gene:FBgn0027610 transcript:FBtr0082747[more]
Dic12.012e-5937.81gene:FBgn0027610 transcript:FBtr0346113[more]
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BLAST of slc25a-18 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc25a111.937e-14065.74solute carrier family 25 member 11 [Source:ZFIN;Ac... [more]
slc25a149.016e-5735.56solute carrier family 25 member 14 [Source:ZFIN;Ac... [more]
slc25a149.016e-5735.56solute carrier family 25 member 14 [Source:ZFIN;Ac... [more]
ucp37.055e-5634.01uncoupling protein 3 [Source:ZFIN;Acc:ZDB-GENE-040... [more]
slc25a143.815e-5435.51solute carrier family 25 member 14 [Source:ZFIN;Ac... [more]
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BLAST of slc25a-18 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc25a111.313e-14065.52solute carrier family 25 (mitochondrial carrier; o... [more]
slc25a111.906e-13565.34solute carrier family 25 (mitochondrial carrier; o... [more]
slc25a111.800e-12059.66solute carrier family 25 (mitochondrial carrier; o... [more]
slc25a111.630e-11265.24solute carrier family 25 (mitochondrial carrier; o... [more]
ucp22.504e-5434.84uncoupling protein 2 (mitochondrial, proton carrie... [more]
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BLAST of slc25a-18 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Slc25a114.488e-14265.64solute carrier family 25 (mitochondrial carrier ox... [more]
Slc25a119.266e-9066.84solute carrier family 25 (mitochondrial carrier ox... [more]
Slc25a142.304e-5635.07solute carrier family 25 (mitochondrial carrier, b... [more]
Slc25a145.744e-5635.07solute carrier family 25 (mitochondrial carrier, b... [more]
Slc25a146.366e-5635.07solute carrier family 25 (mitochondrial carrier, b... [more]
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BLAST of slc25a-18 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9CR62|M2OM_MOUSE3.139e-14165.64Mitochondrial 2-oxoglutarate/malate carrier protei... [more]
sp|P90992|M2OM_CAEEL4.563e-14167.36Mitochondrial 2-oxoglutarate/malate carrier protei... [more]
sp|Q02978|M2OM_HUMAN7.044e-14165.64Mitochondrial 2-oxoglutarate/malate carrier protei... [more]
sp|P22292|M2OM_BOVIN2.882e-14065.29Mitochondrial 2-oxoglutarate/malate carrier protei... [more]
sp|P97700|M2OM_RAT6.568e-13764.26Mitochondrial 2-oxoglutarate/malate carrier protei... [more]
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BLAST of slc25a-18 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YJ720.000e+0100.00Slc25a-18 OS=Schmidtea mediterranea OX=79327 GN=sl... [more]
A0A2C9JGJ09.337e-14971.23Uncharacterized protein OS=Biomphalaria glabrata O... [more]
H2ZMN32.363e-14869.66Uncharacterized protein OS=Ciona savignyi OX=51511... [more]
A0A482WDH92.104e-14768.04Mitochondrial 2-oxoglutarate/malate carrier protei... [more]
A0A1W3JQ642.985e-14769.31mitochondrial 2-oxoglutarate/malate carrier protei... [more]
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BLAST of slc25a-18 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc25a115.955e-14065.40solute carrier family 25 member 11 [Source:NCBI ge... [more]
slc25a115.895e-11266.38solute carrier family 25 member 11 [Source:NCBI ge... [more]
ucp31.121e-5635.42mitochondrial uncoupling protein 2-like [Source:NC... [more]
ucp31.121e-5635.42mitochondrial uncoupling protein 2-like [Source:NC... [more]
ucp31.121e-5635.42mitochondrial uncoupling protein 2-like [Source:NC... [more]
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BLAST of slc25a-18 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ucp27.856e-5034.48uncoupling protein 2 [Source:NCBI gene;Acc:555812][more]
ENSPMAT00000008980.14.542e-2529.74pep scaffold:Pmarinus_7.0:GL478832:29230:40541:-1 ... [more]
slc25a38b1.006e-2326.81solute carrier family 25 member 38b [Source:NCBI g... [more]
slc25a23a1.794e-1825.98solute carrier family 25 member 23a [Source:ZFIN;A... [more]
slc25a55b6.726e-1724.92solute carrier family 25 member 55b [Source:ZFIN;A... [more]
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BLAST of slc25a-18 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
DIC11.781e-4733.45Mitochondrial dicarboxylate carrier; integral memb... [more]
OAC19.366e-4130.72Mitochondrial inner membrane transporter; transpor... [more]
ODC26.782e-2826.32Mitochondrial inner membrane transporter; 2-oxodic... [more]
SFC14.493e-2529.63Mitochondrial succinate-fumarate transporter; tran... [more]
CTP11.973e-2327.87Mitochondrial inner membrane citrate transporter; ... [more]
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BLAST of slc25a-18 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO478732.464e-13563.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO343261.233e-5633.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO369801.454e-5535.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO255094.308e-5236.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8... [more]
EDO399875.880e-4936.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of slc25a-18 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ucp32.404e-5936.24mitochondrial uncoupling protein 2 [Source:NCBI ge... [more]
slc25a142.499e-5735.92solute carrier family 25 member 14 [Source:NCBI ge... [more]
slc25a101.495e-5337.68solute carrier family 25 member 10 [Source:NCBI ge... [more]
SLC25A306.433e-5133.45kidney mitochondrial carrier protein 1 [Source:NCB... [more]
ENSORLT00000028230.17.041e-5033.77mitochondrial uncoupling protein 2 [Source:NCBI ge... [more]
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BLAST of slc25a-18 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000019229.10.000e+099.35SMESG000019229.1[more]
SMESG000073400.11.853e-14061.74SMESG000073400.1[more]
SMESG000046675.13.694e-5839.66SMESG000046675.1[more]
SMESG000062675.13.469e-4731.82SMESG000062675.1[more]
SMESG000020904.16.909e-4334.51SMESG000020904.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30033874
GenBankAKN21586.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033874 ID=SMED30033874|Name=slc25a-18|organism=Schmidtea mediterranea sexual|type=transcript|length=1178bp
TAATTAATGTTTTAATAATTGGAATTAATTAATCTTTTAAATATATTAAA
ATTGGAAATTTAGCTTGAATATTTAATTTTTGATTTTCATCGTAATTATA
ATTGTCACATTTAATGTCATCGCAAAATATTTCCATCCCTAACTATGTTA
AATTTGCTTTTGGTGGTTCAGCAGGAATGATCGCCACCCTTTTCGTTCAA
CCTCTAGATTTAGTTAAAAATCGAATGCAAATGAGTGGTCAGGATGGCTC
AAAGAAAGCTTATAAAAGCAGTTTTGATGCTATTAAACAAATAACAAAAA
ATGAAGGATTATTTGCAATTTATTCTGGTCTTTCTGCTGGTTTATTGAGA
CAGGCCACATACACAACTACAAGATTGGGTGTTTATACAGCTCTTTTTGA
AAAATTTTCATCTAAAGATAAGCCACCTAGTTTCGTTACAAAGGCTGGTA
TAGGAATGAGCGCTGGTTTGATTGGTTCATTTGTCGGAACACCTACGGAA
GTTGCTTTGATTAGAATGACGTCCGATGGAAGACTTCCTATGGACAAAAG
AAGAAACTATCGCAACGTTTTTCATGCTTTAGCTCGAATAGTTCGCGAAG
AAGGTGTATTGGCACTTTGGCGCGGATGCTTACCAACAATGGGTCGAGCA
GCAGTTGTCAATCTTGCCCAGCTAGCATCTTATTCACAAGCTAAGCAAAT
GATACTTGAAACCGAATTATTCAACGATGGAATCTTTGTCCATTTTGGAG
CCAGTATGATCAGCGGTTTCATAACTACTGTTGCATCTATGCCAGTTGAT
ATTGTTAAAACTAGAATTCAAAACATGACAGTTGTTAACGGGGTTGCTGA
GTATTCTGGGGCAATTAATGCATTTATTAGAATTACGAAACATGAGGGTG
TATTAAGTTTGTGGAAAGGCTTTACACCGTATTTCTTGCGTCTTGGTCCT
CATACTGTAATCACGTTTGTCGTGCTTGAACAAATGAATACGGCGTACAA
AAATGTCGCCCATCGAAAGGTAGTTCAGCAACAGAAAGAAAAGGAGCCTC
GTTAAATAGAATCTTTATATCTTTAGAGCTCTTTGAGTTCAATATTTGAA
TAATCAATGAAATCAATGTGAACAATAATTATGATAGAAAATTTTACCAA
TAAATATTTTTTGTATTTTTAAAAAAAA
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protein sequence of SMED30033874-orf-1

>SMED30033874-orf-1 ID=SMED30033874-orf-1|Name=SMED30033874-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=314bp
MSSQNISIPNYVKFAFGGSAGMIATLFVQPLDLVKNRMQMSGQDGSKKAY
KSSFDAIKQITKNEGLFAIYSGLSAGLLRQATYTTTRLGVYTALFEKFSS
KDKPPSFVTKAGIGMSAGLIGSFVGTPTEVALIRMTSDGRLPMDKRRNYR
NVFHALARIVREEGVLALWRGCLPTMGRAAVVNLAQLASYSQAKQMILET
ELFNDGIFVHFGASMISGFITTVASMPVDIVKTRIQNMTVVNGVAEYSGA
INAFIRITKHEGVLSLWKGFTPYFLRLGPHTVITFVVLEQMNTAYKNVAH
RKVVQQQKEKEPR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR023395Mt_carrier_dom_sf
IPR018108Mitochondrial_sb/sol_carrier
Vocabulary: biological process
TermDefinition
GO:0006810transport
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR023395Mitochondrial carrier domain superfamilyGENE3DG3DSA:1.50.40.10coord: 10..311
e-value: 1.7E-86
score: 291.6
IPR023395Mitochondrial carrier domain superfamilySUPERFAMILYSSF103506Mitochondrial carriercoord: 9..291
IPR018108Mitochondrial substrate/solute carrierPFAMPF00153Mito_carrcoord: 105..199
e-value: 3.3E-17
score: 62.2
coord: 9..99
e-value: 1.8E-21
score: 75.9
coord: 206..296
e-value: 1.2E-19
score: 70.0
IPR018108Mitochondrial substrate/solute carrierPROSITEPS50920SOLCARcoord: 205..294
score: 26.825
IPR018108Mitochondrial substrate/solute carrierPROSITEPS50920SOLCARcoord: 8..97
score: 25.645
IPR018108Mitochondrial substrate/solute carrierPROSITEPS50920SOLCARcoord: 105..196
score: 25.817
NoneNo IPR availablePANTHERPTHR45618FAMILY NOT NAMEDcoord: 8..292
NoneNo IPR availablePANTHERPTHR45618:SF9MITOCHONDRIAL 2-OXOGLUTARATE/MALATE CARRIER PROTEINcoord: 8..292
NoneNo IPR availableTMHMMTMhelixcoord: 206..228
NoneNo IPR availableTMHMMTMhelixcoord: 7..29
NoneNo IPR availableTMHMMTMhelixcoord: 111..133