BTEB transcription factor

Overview
NameBTEB transcription factor
Smed IDSMED30033868
Length (bp)843
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of BTEB transcription factor (SMED30033868) t-SNE clustered cells

Violin plots show distribution of expression levels for BTEB transcription factor (SMED30033868) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of BTEB transcription factor (SMED30033868) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for BTEB transcription factor (SMED30033868) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033868

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30033868h1SMcG0001434 dd_Smed_v4_12264_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30033868h1SMcG0001434 dd_Smed_v4_12264_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30033868h1SMcG0001434 dd_Smed_v4_12264_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of BTEB transcription factor vs. Ensembl Human
Match: KLF4 (Kruppel like factor 4 [Source:HGNC Symbol;Acc:HGNC:6348])

HSP 1 Score: 138.272 bits (347), Expect = 2.957e-40
Identity = 65/110 (59.09%), Postives = 77/110 (70.00%), Query Frame = 2 
Query:  365 LIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            + +E   K  R S   KR +        +CDY GC K Y K SHLKAH R HTGEKPY C+W  CGWKFARSDELTRHYRKHTG RP++CQ CD++F+RSDHL LH ++H
Sbjct:   41 MPEEPKPKRGRRSWPRKRTAT------HTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRH 144

HSP 2 Score: 53.9138 bits (128), Expect = 1.513e-8
Identity = 25/56 (44.64%), Postives = 34/56 (60.71%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C++  CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:   62 HTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHT 117
[Close]
BLAST of BTEB transcription factor vs. Ensembl Human
Match: KLF12 (Kruppel like factor 12 [Source:HGNC Symbol;Acc:HGNC:6346])

HSP 1 Score: 142.124 bits (357), Expect = 4.576e-39
Identity = 60/81 (74.07%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+EGC KVY K SHLKAH R HTGEKPY C W  C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H
Sbjct:  319 CDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRH 399
[Close]
BLAST of BTEB transcription factor vs. Ensembl Human
Match: KLF2 (Kruppel like factor 2 [Source:HGNC Symbol;Acc:HGNC:6347])

HSP 1 Score: 140.584 bits (353), Expect = 7.319e-39
Identity = 64/112 (57.14%), Postives = 79/112 (70.54%), Query Frame = 2 
Query:  359 LQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            L+L++ + ++  R S   KR +        +C Y GC K Y K SHLKAH R HTGEKPY CNW  CGWKFARSDELTRHYRKHTG RP++C  CD++F+RSDHL LH ++H
Sbjct:  250 LELLEAKPKRGRR-SWPRKRTAT------HTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRH 354

HSP 2 Score: 55.4546 bits (132), Expect = 2.874e-8
Identity = 25/56 (44.64%), Postives = 34/56 (60.71%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C++  CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:  272 HTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHT 327
[Close]
BLAST of BTEB transcription factor vs. Ensembl Human
Match: KLF4 (Kruppel like factor 4 [Source:HGNC Symbol;Acc:HGNC:6348])

HSP 1 Score: 142.895 bits (359), Expect = 1.063e-38
Identity = 59/82 (71.95%), Postives = 68/82 (82.93%), Query Frame = 2 
Query:  449 SCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            +CDY GC K Y K SHLKAH R HTGEKPY C+W  CGWKFARSDELTRHYRKHTG RP++CQ CD++F+RSDHL LH ++H
Sbjct:  397 TCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRH 478

HSP 2 Score: 56.6102 bits (135), Expect = 1.614e-8
Identity = 25/56 (44.64%), Postives = 34/56 (60.71%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C++  CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:  396 HTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHT 451
[Close]
BLAST of BTEB transcription factor vs. Ensembl Human
Match: KLF8 (Kruppel like factor 8 [Source:HGNC Symbol;Acc:HGNC:6351])

HSP 1 Score: 138.658 bits (348), Expect = 4.089e-38
Identity = 60/98 (61.22%), Postives = 73/98 (74.49%), Query Frame = 2 
Query:  401 SCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            S D+KR        +  CD+ GC KVY K SHLKAH R+HTGEKPY C W  C WKFARSDELTRH+RKHTG +P++C  C++SF+RSDHL LH+R+H
Sbjct:  265 SLDLKR------RRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRH 356
[Close]
BLAST of BTEB transcription factor vs. Ensembl Celegans
Match: klf-3 (Kruppel-Like Factor (Zinc finger protein) [Source:UniProtKB/TrEMBL;Acc:P91329])

HSP 1 Score: 131.724 bits (330), Expect = 2.790e-36
Identity = 55/83 (66.27%), Postives = 67/83 (80.72%), Query Frame = 2 
Query:  449 SCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHS 697
            +C Y GCFK Y+K SHLKAH R H+GEKP+ C W +C WKFARSDELTRH RKHTG +P++C  CD++FARSDHL LH ++HS
Sbjct:  225 ACTYPGCFKKYSKSSHLKAHERTHSGEKPFVCKWQNCSWKFARSDELTRHMRKHTGDKPFRCSLCDRNFARSDHLSLHMKRHS 307

HSP 2 Score: 58.5362 bits (140), Expect = 1.091e-9
Identity = 30/74 (40.54%), Postives = 42/74 (56.76%), Query Frame = 2 
Query:  482 NKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            NKR+     F VH      +C +P C  K+++S  L  H R H+G++P+ C+W  C   FARSD L  H RKH+
Sbjct:  212 NKRNPTDKKFVVH------ACTYPGCFKKYSKSSHLKAHERTHSGEKPFVCKWQNCSWKFARSDELTRHMRKHT 279
[Close]
BLAST of BTEB transcription factor vs. Ensembl Celegans
Match: klf-3 (Kruppel-Like Factor (Zinc finger protein) [Source:UniProtKB/TrEMBL;Acc:P91329])

HSP 1 Score: 131.724 bits (330), Expect = 2.801e-36
Identity = 55/85 (64.71%), Postives = 68/85 (80.00%), Query Frame = 2 
Query:  443 MFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHS 697
            + +C Y GCFK Y+K SHLKAH R H+GEKP+ C W +C WKFARSDELTRH RKHTG +P++C  CD++FARSDHL LH ++HS
Sbjct:  229 VHACTYPGCFKKYSKSSHLKAHERTHSGEKPFVCKWQNCSWKFARSDELTRHMRKHTGDKPFRCSLCDRNFARSDHLSLHMKRHS 313

HSP 2 Score: 58.5362 bits (140), Expect = 1.051e-9
Identity = 30/74 (40.54%), Postives = 42/74 (56.76%), Query Frame = 2 
Query:  482 NKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            NKR+     F VH      +C +P C  K+++S  L  H R H+G++P+ C+W  C   FARSD L  H RKH+
Sbjct:  218 NKRNPTDKKFVVH------ACTYPGCFKKYSKSSHLKAHERTHSGEKPFVCKWQNCSWKFARSDELTRHMRKHT 285
[Close]
BLAST of BTEB transcription factor vs. Ensembl Celegans
Match: klf-1 (Kruppel-Like Factor (Zinc finger protein) [Source:UniProtKB/TrEMBL;Acc:Q9TZ64])

HSP 1 Score: 134.035 bits (336), Expect = 9.341e-36
Identity = 55/81 (67.90%), Postives = 64/81 (79.01%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C +  C KVY K SHLKAHFR HTGEKPY C+W  C W+FARSDELTRHYRKHTG RP+KC  C ++F+RSDHL LH ++H
Sbjct:  416 CTHPNCGKVYTKSSHLKAHFRTHTGEKPYECSWDGCDWRFARSDELTRHYRKHTGDRPFKCSQCSRAFSRSDHLSLHMKRH 496

HSP 2 Score: 63.1586 bits (152), Expect = 4.296e-11
Identity = 27/54 (50.00%), Postives = 35/54 (64.81%), Query Frame = 2 
Query:  542 CNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            C  P+CG  + +S  L  H+R HTG++PY+C W  CD  FARSD L  H RKH+
Sbjct:  416 CTHPNCGKVYTKSSHLKAHFRTHTGEKPYECSWDGCDWRFARSDELTRHYRKHT 469
[Close]
BLAST of BTEB transcription factor vs. Ensembl Celegans
Match: klf-1 (Kruppel-Like Factor (Zinc finger protein) [Source:UniProtKB/TrEMBL;Acc:Q9TZ64])

HSP 1 Score: 134.035 bits (336), Expect = 9.341e-36
Identity = 55/81 (67.90%), Postives = 64/81 (79.01%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C +  C KVY K SHLKAHFR HTGEKPY C+W  C W+FARSDELTRHYRKHTG RP+KC  C ++F+RSDHL LH ++H
Sbjct:  416 CTHPNCGKVYTKSSHLKAHFRTHTGEKPYECSWDGCDWRFARSDELTRHYRKHTGDRPFKCSQCSRAFSRSDHLSLHMKRH 496

HSP 2 Score: 63.1586 bits (152), Expect = 4.296e-11
Identity = 27/54 (50.00%), Postives = 35/54 (64.81%), Query Frame = 2 
Query:  542 CNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            C  P+CG  + +S  L  H+R HTG++PY+C W  CD  FARSD L  H RKH+
Sbjct:  416 CTHPNCGKVYTKSSHLKAHFRTHTGEKPYECSWDGCDWRFARSDELTRHYRKHT 469
[Close]
BLAST of BTEB transcription factor vs. Ensembl Celegans
Match: klf-2 (Kruppel-Like Factor (Zinc finger protein) [Source:UniProtKB/TrEMBL;Acc:O62259])

HSP 1 Score: 129.413 bits (324), Expect = 1.841e-35
Identity = 54/81 (66.67%), Postives = 64/81 (79.01%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C Y+GC KVY K SHL AH RVH+GEKPY C WP C W+FARSDELTRHYRKHTG +P+ C+ C + F+RSDHL LH ++H
Sbjct:  200 CFYQGCGKVYTKSSHLTAHERVHSGEKPYPCEWPGCSWRFARSDELTRHYRKHTGAKPFACKECSRKFSRSDHLQLHMKRH 280

HSP 2 Score: 54.299 bits (129), Expect = 2.396e-8
Identity = 25/58 (43.10%), Postives = 35/58 (60.34%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHSES 703
            + C +  CG  + +S  LT H R H+G++PY C+W  C   FARSD L  H RKH+ +
Sbjct:  198 HKCFYQGCGKVYTKSSHLTAHERVHSGEKPYPCEWPGCSWRFARSDELTRHYRKHTGA 255

HSP 3 Score: 48.1358 bits (113), Expect = 2.390e-6
Identity = 22/58 (37.93%), Postives = 34/58 (58.62%), Query Frame = 2 
Query:  437 ESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKH 610
            E  + C++ GC   + +   L  H+R HTG KP++C   +C  KF+RSD L  H ++H
Sbjct:  225 EKPYPCEWPGCSWRFARSDELTRHYRKHTGAKPFACK--ECSRKFSRSDHLQLHMKRH 280
[Close]
BLAST of BTEB transcription factor vs. Ensembl Fly
Match: dar1 (gene:FBgn0263239 transcript:FBtr0113134)

HSP 1 Score: 145.206 bits (365), Expect = 6.453e-39
Identity = 66/116 (56.90%), Postives = 83/116 (71.55%), Query Frame = 2 
Query:  356 ILQLIQERNQKFNR---PSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            I  L+  R  ++NR   P  + +RI +        CD+ GC KVY K SHLKAH R+HTGEKPY+C WP+C W+FARSDELTRHYRKHTG +P+KC  C++SFARSDHL LH ++H
Sbjct:  639 IASLMSVRTVRYNRRNNPELEKRRIHH--------CDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRH 746
[Close]
BLAST of BTEB transcription factor vs. Ensembl Fly
Match: CG42741 (gene:FBgn0261705 transcript:FBtr0303203)

HSP 1 Score: 133.65 bits (335), Expect = 2.084e-36
Identity = 58/81 (71.60%), Postives = 65/81 (80.25%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD EGC KVY K SHLKAH R HTGEKPY C W  C W+FARSDELTRHYRKHTG +P++CQ C +SF+RSDHL LH R+H
Sbjct:  282 CDTEGCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFSRSDHLSLHMRRH 362
[Close]
BLAST of BTEB transcription factor vs. Ensembl Fly
Match: luna (gene:FBgn0040765 transcript:FBtr0345675)

HSP 1 Score: 131.339 bits (329), Expect = 2.273e-34
Identity = 55/81 (67.90%), Postives = 65/81 (80.25%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C + GC KVY K SHLKAH R HTGEKPY C+W  C W+FARSDELTRHYRKHTG +P+KC+ CD+ F+RSDHL LH ++H
Sbjct:  489 CQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDHLALHMKRH 569
[Close]
BLAST of BTEB transcription factor vs. Ensembl Fly
Match: luna (gene:FBgn0040765 transcript:FBtr0088210)

HSP 1 Score: 131.339 bits (329), Expect = 2.273e-34
Identity = 55/81 (67.90%), Postives = 65/81 (80.25%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C + GC KVY K SHLKAH R HTGEKPY C+W  C W+FARSDELTRHYRKHTG +P+KC+ CD+ F+RSDHL LH ++H
Sbjct:  489 CQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDHLALHMKRH 569
[Close]
BLAST of BTEB transcription factor vs. Ensembl Fly
Match: luna (gene:FBgn0040765 transcript:FBtr0333066)

HSP 1 Score: 131.339 bits (329), Expect = 2.273e-34
Identity = 55/81 (67.90%), Postives = 65/81 (80.25%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C + GC KVY K SHLKAH R HTGEKPY C+W  C W+FARSDELTRHYRKHTG +P+KC+ CD+ F+RSDHL LH ++H
Sbjct:  489 CQFLGCKKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCRNCDRCFSRSDHLALHMKRH 569
[Close]
BLAST of BTEB transcription factor vs. Ensembl Zebrafish
Match: klf8 (Kruppel-like factor 8 [Source:ZFIN;Acc:ZDB-GENE-070424-152])

HSP 1 Score: 140.969 bits (354), Expect = 2.317e-39
Identity = 57/81 (70.37%), Postives = 68/81 (83.95%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CDY+GC KVY K SHLKAH R+HTGEKPY C W  C W+FARSDELTRH+RKHTG +P++C  CD+SF+RSDHL LH+R+H
Sbjct:  252 CDYDGCNKVYTKSSHLKAHRRIHTGEKPYQCTWEGCTWRFARSDELTRHFRKHTGIKPFRCTDCDRSFSRSDHLALHRRRH 332
[Close]
BLAST of BTEB transcription factor vs. Ensembl Zebrafish
Match: klf8 (Kruppel-like factor 8 [Source:ZFIN;Acc:ZDB-GENE-070424-152])

HSP 1 Score: 140.969 bits (354), Expect = 3.191e-39
Identity = 57/81 (70.37%), Postives = 68/81 (83.95%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CDY+GC KVY K SHLKAH R+HTGEKPY C W  C W+FARSDELTRH+RKHTG +P++C  CD+SF+RSDHL LH+R+H
Sbjct:  260 CDYDGCNKVYTKSSHLKAHRRIHTGEKPYQCTWEGCTWRFARSDELTRHFRKHTGIKPFRCTDCDRSFSRSDHLALHRRRH 340
[Close]
BLAST of BTEB transcription factor vs. Ensembl Zebrafish
Match: klf12a (Kruppel-like factor 12a [Source:ZFIN;Acc:ZDB-GENE-030131-9188])

HSP 1 Score: 140.969 bits (354), Expect = 4.934e-39
Identity = 59/88 (67.05%), Postives = 72/88 (81.82%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSESSTVL 715
            C++EGC KVY K SHLKAH R HTGEKPY C W +C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H+  + ++
Sbjct:  286 CEFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWDNCTWKFARSDELTRHYRKHTGVKPFKCSDCDRSFSRSDHLALHRRRHAPQTCLV 373
[Close]
BLAST of BTEB transcription factor vs. Ensembl Zebrafish
Match: klf12a (Kruppel-like factor 12a [Source:ZFIN;Acc:ZDB-GENE-030131-9188])

HSP 1 Score: 140.969 bits (354), Expect = 4.934e-39
Identity = 59/88 (67.05%), Postives = 72/88 (81.82%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSESSTVL 715
            C++EGC KVY K SHLKAH R HTGEKPY C W +C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H+  + ++
Sbjct:  286 CEFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWDNCTWKFARSDELTRHYRKHTGVKPFKCSDCDRSFSRSDHLALHRRRHAPQTCLV 373
[Close]
BLAST of BTEB transcription factor vs. Ensembl Zebrafish
Match: klf12a (Kruppel-like factor 12a [Source:ZFIN;Acc:ZDB-GENE-030131-9188])

HSP 1 Score: 140.969 bits (354), Expect = 4.934e-39
Identity = 59/88 (67.05%), Postives = 72/88 (81.82%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSESSTVL 715
            C++EGC KVY K SHLKAH R HTGEKPY C W +C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H+  + ++
Sbjct:  286 CEFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWDNCTWKFARSDELTRHYRKHTGVKPFKCSDCDRSFSRSDHLALHRRRHAPQTCLV 373
[Close]
BLAST of BTEB transcription factor vs. Ensembl Xenopus
Match: nudc (nudC nuclear distribution protein [Source:Xenbase;Acc:XB-GENE-985468])

HSP 1 Score: 142.51 bits (358), Expect = 2.388e-39
Identity = 60/81 (74.07%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+EGC KVY K SHLKAH R HTGEKPY C W  C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H
Sbjct:  304 CDFEGCNKVYTKSSHLKAHRRTHTGEKPYMCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRH 384
[Close]
BLAST of BTEB transcription factor vs. Ensembl Xenopus
Match: klf4 (Kruppel-like factor 4 (gut) [Source:NCBI gene;Acc:550034])

HSP 1 Score: 142.895 bits (359), Expect = 8.191e-39
Identity = 58/82 (70.73%), Postives = 68/82 (82.93%), Query Frame = 2 
Query:  449 SCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            +C+Y GC K Y K SHLKAH R HTGEKPY C+W  CGWKFARSDELTRHYRKHTG RP++CQ CD++F+RSDHL LH ++H
Sbjct:  395 TCEYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWEGCGWKFARSDELTRHYRKHTGHRPFQCQRCDRAFSRSDHLALHMKRH 476

HSP 2 Score: 56.9954 bits (136), Expect = 1.051e-8
Identity = 25/56 (44.64%), Postives = 33/56 (58.93%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C +  CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:  394 HTCEYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWEGCGWKFARSDELTRHYRKHT 449
[Close]
BLAST of BTEB transcription factor vs. Ensembl Xenopus
Match: klf4 (Kruppel-like factor 4 (gut) [Source:NCBI gene;Acc:550034])

HSP 1 Score: 142.51 bits (358), Expect = 1.031e-38
Identity = 58/82 (70.73%), Postives = 68/82 (82.93%), Query Frame = 2 
Query:  449 SCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            +C+Y GC K Y K SHLKAH R HTGEKPY C+W  CGWKFARSDELTRHYRKHTG RP++CQ CD++F+RSDHL LH ++H
Sbjct:  375 TCEYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWEGCGWKFARSDELTRHYRKHTGHRPFQCQRCDRAFSRSDHLALHMKRH 456

HSP 2 Score: 56.6102 bits (135), Expect = 1.375e-8
Identity = 25/56 (44.64%), Postives = 33/56 (58.93%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C +  CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:  374 HTCEYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWEGCGWKFARSDELTRHYRKHT 429
[Close]
BLAST of BTEB transcription factor vs. Ensembl Xenopus
Match: KLF5 (Kruppel-like factor 5 (intestinal) [Source:NCBI gene;Acc:100489339])

HSP 1 Score: 141.354 bits (355), Expect = 1.542e-38
Identity = 64/119 (53.78%), Postives = 79/119 (66.39%), Query Frame = 2 
Query:  341 SQIDLILQLIQE-RNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            +Q+ +    IQ  R  + N P  + +RI          CDY GC KVY K SHLKAH R HTGEKPY C W  C W+FARSDELTRHYRKHTG +P++C  C++SF+RSDHL LH ++H
Sbjct:  322 AQVQITAPAIQSVRYNRRNNPDLEKRRI--------HYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCAVCNRSFSRSDHLALHMKRH 432

HSP 2 Score: 62.003 bits (149), Expect = 2.491e-10
Identity = 27/56 (48.21%), Postives = 35/56 (62.50%), Query Frame = 2 
Query:  542 CNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHSES 703
            C++P C   + +S  L  H R HTG++PYKC W  CD  FARSD L  H RKH+ +
Sbjct:  352 CDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGA 407
[Close]
BLAST of BTEB transcription factor vs. Ensembl Xenopus
Match: ica1 (islet cell autoantigen 1 [Source:Xenbase;Acc:XB-GENE-974152])

HSP 1 Score: 139.428 bits (350), Expect = 1.877e-38
Identity = 58/81 (71.60%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+EGC KVY K SHLKAH R+HTGEKPY C W  C WKFARSDELTRH+RKHTG +P+ C  CD+SF+RSDHL LH+R+H
Sbjct:  273 CDFEGCNKVYTKSSHLKAHRRIHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFLCSDCDRSFSRSDHLALHRRRH 353
[Close]
BLAST of BTEB transcription factor vs. Ensembl Mouse
Match: Klf12 (Kruppel-like factor 12 [Source:MGI Symbol;Acc:MGI:1333796])

HSP 1 Score: 142.51 bits (358), Expect = 2.743e-39
Identity = 60/81 (74.07%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+EGC KVY K SHLKAH R HTGEKPY C W  C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H
Sbjct:  319 CDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRH 399
[Close]
BLAST of BTEB transcription factor vs. Ensembl Mouse
Match: Klf12 (Kruppel-like factor 12 [Source:MGI Symbol;Acc:MGI:1333796])

HSP 1 Score: 142.51 bits (358), Expect = 2.743e-39
Identity = 60/81 (74.07%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+EGC KVY K SHLKAH R HTGEKPY C W  C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H
Sbjct:  319 CDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRH 399
[Close]
BLAST of BTEB transcription factor vs. Ensembl Mouse
Match: Klf4 (Kruppel-like factor 4 (gut) [Source:MGI Symbol;Acc:MGI:1342287])

HSP 1 Score: 143.665 bits (361), Expect = 3.607e-39
Identity = 66/110 (60.00%), Postives = 77/110 (70.00%), Query Frame = 2 
Query:  365 LIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            L +E   K  R S   KR +        +CDY GC K Y K SHLKAH R HTGEKPY C+W  CGWKFARSDELTRHYRKHTG RP++CQ CD++F+RSDHL LH ++H
Sbjct:  379 LPEEPKPKRGRRSWPRKRTAT------HTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRH 482

HSP 2 Score: 56.6102 bits (135), Expect = 9.977e-9
Identity = 25/56 (44.64%), Postives = 34/56 (60.71%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C++  CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:  400 HTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHT 455
[Close]
BLAST of BTEB transcription factor vs. Ensembl Mouse
Match: Klf8 (Kruppel-like factor 8 [Source:MGI Symbol;Acc:MGI:2442430])

HSP 1 Score: 137.887 bits (346), Expect = 6.522e-38
Identity = 56/81 (69.14%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+ GC KVY K SHLKAH R+HTGEKPY C W  C WKFARSDELTRH+RKHTG +P++C  C++SF+RSDHL LH+R+H
Sbjct:  272 CDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRH 352
[Close]
BLAST of BTEB transcription factor vs. Ensembl Mouse
Match: Klf8 (Kruppel-like factor 8 [Source:MGI Symbol;Acc:MGI:2442430])

HSP 1 Score: 137.887 bits (346), Expect = 6.522e-38
Identity = 56/81 (69.14%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+ GC KVY K SHLKAH R+HTGEKPY C W  C WKFARSDELTRH+RKHTG +P++C  C++SF+RSDHL LH+R+H
Sbjct:  272 CDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRH 352
[Close]
BLAST of BTEB transcription factor vs. UniProt/SwissProt
Match: sp|O35738|KLF12_MOUSE (Krueppel-like factor 12 OS=Mus musculus OX=10090 GN=Klf12 PE=1 SV=2)

HSP 1 Score: 142.51 bits (358), Expect = 1.918e-38
Identity = 60/81 (74.07%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+EGC KVY K SHLKAH R HTGEKPY C W  C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H
Sbjct:  319 CDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRH 399
[Close]
BLAST of BTEB transcription factor vs. UniProt/SwissProt
Match: sp|Q9Y4X4|KLF12_HUMAN (Krueppel-like factor 12 OS=Homo sapiens OX=9606 GN=KLF12 PE=1 SV=2)

HSP 1 Score: 142.124 bits (357), Expect = 2.197e-38
Identity = 60/81 (74.07%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+EGC KVY K SHLKAH R HTGEKPY C W  C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H
Sbjct:  319 CDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRH 399
[Close]
BLAST of BTEB transcription factor vs. UniProt/SwissProt
Match: sp|Q60793|KLF4_MOUSE (Krueppel-like factor 4 OS=Mus musculus OX=10090 GN=Klf4 PE=1 SV=3)

HSP 1 Score: 143.665 bits (361), Expect = 2.523e-38
Identity = 66/110 (60.00%), Postives = 77/110 (70.00%), Query Frame = 2 
Query:  365 LIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            L +E   K  R S   KR +        +CDY GC K Y K SHLKAH R HTGEKPY C+W  CGWKFARSDELTRHYRKHTG RP++CQ CD++F+RSDHL LH ++H
Sbjct:  379 LPEEPKPKRGRRSWPRKRTAT------HTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRH 482

HSP 2 Score: 56.6102 bits (135), Expect = 6.979e-8
Identity = 25/56 (44.64%), Postives = 34/56 (60.71%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C++  CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:  400 HTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHT 455
[Close]
BLAST of BTEB transcription factor vs. UniProt/SwissProt
Match: sp|Q9Y5W3|KLF2_HUMAN (Krueppel-like factor 2 OS=Homo sapiens OX=9606 GN=KLF2 PE=1 SV=2)

HSP 1 Score: 140.584 bits (353), Expect = 3.515e-38
Identity = 64/112 (57.14%), Postives = 79/112 (70.54%), Query Frame = 2 
Query:  359 LQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            L+L++ + ++  R S   KR +        +C Y GC K Y K SHLKAH R HTGEKPY CNW  CGWKFARSDELTRHYRKHTG RP++C  CD++F+RSDHL LH ++H
Sbjct:  250 LELLEAKPKRGRR-SWPRKRTAT------HTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRH 354

HSP 2 Score: 55.4546 bits (132), Expect = 1.380e-7
Identity = 25/56 (44.64%), Postives = 34/56 (60.71%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C++  CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:  272 HTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHT 327
[Close]
BLAST of BTEB transcription factor vs. UniProt/SwissProt
Match: sp|Q9VZN4|DAR1_DROME (Dendritic arbor reduction protein 1 OS=Drosophila melanogaster OX=7227 GN=dar1 PE=2 SV=2)

HSP 1 Score: 145.206 bits (365), Expect = 6.469e-38
Identity = 66/116 (56.90%), Postives = 83/116 (71.55%), Query Frame = 2 
Query:  356 ILQLIQERNQKFNR---PSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            I  L+  R  ++NR   P  + +RI +        CD+ GC KVY K SHLKAH R+HTGEKPY+C WP+C W+FARSDELTRHYRKHTG +P+KC  C++SFARSDHL LH ++H
Sbjct:  639 IASLMSVRTVRYNRRNNPELEKRRIHH--------CDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRH 746
[Close]
BLAST of BTEB transcription factor vs. TrEMBL
Match: A0A448XRW0 (Uncharacterized protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS36745 PE=4 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 6.747e-40
Identity = 64/87 (73.56%), Postives = 72/87 (82.76%), Query Frame = 2 
Query:  443 MFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSES 703
            +F C YEGC K Y+K SHLKAH R HTGEKPY+C WP C WKFARSDELTRH RKHTG+RP+KC+ C++SFARSDHL LH RKHS S
Sbjct:   65 VFRCVYEGCSKSYSKSSHLKAHVRTHTGEKPYACRWPGCNWKFARSDELTRHSRKHTGERPFKCRVCERSFARSDHLALHIRKHSSS 151
[Close]
BLAST of BTEB transcription factor vs. TrEMBL
Match: A0A085MCM7 (Uncharacterized protein OS=Trichuris suis OX=68888 GN=M513_04155 PE=4 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 7.050e-39
Identity = 81/209 (38.76%), Postives = 115/209 (55.02%), Query Frame = 2 
Query:  110 MTHFKPE--------EISEFSLMLPITPLYDDTSGCDDFSDYEHLLDYDFIIENTCQIRNDQNDFKFSRKEKDQR-IFNVIPK-LEMS-QIDLILQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSES 703
            M +F P+         + ++S M      Y     C           YD ++ +    RN     +    E D + IF   P+  ++S    L++ ++QE +++F R     +R    I   +  C + GC K Y K SHLKAH R+HTGEKPY C+WP+CGWKFARSDELTRH RKHTG RP++C  CD++FARSDHL LH ++H+ +
Sbjct:  240 MANFPPQPNLPYGQAAVQDYSTMALQMAPYKQYPACYSTMTPPESPSYDHLMTSG---RNMDMSIRSQVAEPDGKNIFYATPRDTQVSDPTALMMMMMQESSREFERNRPKPRRQKRTI---VHGCTHPGCLKTYTKSSHLKAHMRIHTGEKPYWCSWPECGWKFARSDELTRHIRKHTGDRPFRCTLCDRAFARSDHLTLHMKRHNAA 442
[Close]
BLAST of BTEB transcription factor vs. TrEMBL
Match: A0A077Z1P2 (Zinc finger protein OS=Trichuris trichiura OX=36087 GN=TTRE_0000268201 PE=4 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 9.989e-39
Identity = 74/168 (44.05%), Postives = 104/168 (61.90%), Query Frame = 2 
Query:  206 DYEHLLDYDFIIENTCQIRNDQNDFKFSRKEKDQRIFNVIPK-LEMS-QIDLILQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSES 703
             Y+HL+     ++    IRN   +         + IF   P+  ++S    L++ ++QE +++F R     +R    I   +  C + GC K Y K SHLKAH R+HTGEKPY C+WP+CGWKFARSDELTRH RKHTG RP++C  CD++FARSDHL LH ++H+ +
Sbjct:  267 SYDHLMTSGRTVD--MSIRNQVVE------PTGKNIFYATPRETQVSDPAALMMMMMQEGSREFERNRPKPRRQKRTI---VHGCTHPGCLKTYTKSSHLKAHMRIHTGEKPYWCSWPECGWKFARSDELTRHIRKHTGDRPFRCTLCDRAFARSDHLTLHMKRHNAA 423
[Close]
BLAST of BTEB transcription factor vs. TrEMBL
Match: A0A183AAU5 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS4080 PE=4 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 1.242e-38
Identity = 71/170 (41.76%), Postives = 97/170 (57.06%), Query Frame = 2 
Query:  185 SGCDDFSDYEHLLDYDFIIENTCQIRNDQNDFKFSRKEKDQRIFNVIPKLEMSQIDLILQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            S  D+F+  +   +Y     NT  +     D+      K+ ++   +P++  +       +   R     RP+ +   +       +  C+Y GC K Y+K SHLKAH R HTGEKPY+C WPDCGW+FARSDELTRH RKHTG RP+ C+ C ++FARSDHL LH RKH
Sbjct:  130 SNSDEFTSSQACPNYSHTPPNTPTVPGSAFDYG---TPKNSQLPMRVPRMSYTSTAKNAPVTNRRR----RPAVNQSTV-------VHRCEYSGCQKSYSKSSHLKAHIRTHTGEKPYACLWPDCGWRFARSDELTRHSRKHTGVRPFHCRLCRRTFARSDHLALHTRKH 285
[Close]
BLAST of BTEB transcription factor vs. TrEMBL
Match: T1JPZ2 (Uncharacterized protein OS=Tetranychus urticae OX=32264 GN=107362272 PE=4 SV=1)

HSP 1 Score: 142.124 bits (357), Expect = 1.774e-38
Identity = 63/92 (68.48%), Postives = 73/92 (79.35%), Query Frame = 2 
Query:  419 ISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            I N+    +  CD+EGC KVY K SHLKAH R HTGEKPY+CNW  C WKFARSDELTRHYRKHTGQ+P+KCQ C +SF+RSDHL LH ++H
Sbjct:   64 IENLRRRKVHKCDFEGCEKVYTKSSHLKAHKRTHTGEKPYTCNWEGCTWKFARSDELTRHYRKHTGQKPFKCQLCQRSFSRSDHLSLHMKRH 155
[Close]
BLAST of BTEB transcription factor vs. Ensembl Cavefish
Match: ENSAMXT00000049113.1 (pep primary_assembly:Astyanax_mexicanus-2.0:16:5432533:5434525:1 gene:ENSAMXG00000030891.1 transcript:ENSAMXT00000049113.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 137.887 bits (346), Expect = 2.620e-40
Identity = 66/127 (51.97%), Postives = 83/127 (65.35%), Query Frame = 2 
Query:  314 FNVIPKLEMSQIDLILQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
             NV+       +DL+    Q R ++  R +   KR +        SC++ GC K Y K SHLKAH R HTGEKPY CNW  CGWKFARSDELTRHYRKHTG RP++C  C+++F+RSDHL LH ++H
Sbjct:   34 LNVLTPPSSPLLDLLRADEQSRPRRGRR-TWARKRAAT------HSCEFAGCGKTYTKSSHLKAHMRTHTGEKPYHCNWEGCGWKFARSDELTRHYRKHTGHRPFQCHLCERAFSRSDHLALHMKRH 153

HSP 2 Score: 55.4546 bits (132), Expect = 3.468e-9
Identity = 26/56 (46.43%), Postives = 33/56 (58.93%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            +SC +  CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:   71 HSCEFAGCGKTYTKSSHLKAHMRTHTGEKPYHCNWEGCGWKFARSDELTRHYRKHT 126
[Close]
BLAST of BTEB transcription factor vs. Ensembl Cavefish
Match: ENSAMXT00000048628.1 (Kruppel like factor 4 [Source:NCBI gene;Acc:103040964])

HSP 1 Score: 142.895 bits (359), Expect = 9.002e-40
Identity = 67/110 (60.91%), Postives = 78/110 (70.91%), Query Frame = 2 
Query:  365 LIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            L +E   K  R S   KRI+        +CDY GC K Y K SHLKAH R HTGEKPY C+W  CGWKFARSDELTRHYRKHTG RP++CQ CD++F+RSDHL LH ++H
Sbjct:  280 LPEEPKPKRGRRSWPRKRIAT------HTCDYVGCGKTYTKSSHLKAHHRTHTGEKPYHCDWEGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRH 383

HSP 2 Score: 56.6102 bits (135), Expect = 8.185e-9
Identity = 25/56 (44.64%), Postives = 35/56 (62.50%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C++  CG  + +S  L  H+R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:  301 HTCDYVGCGKTYTKSSHLKAHHRTHTGEKPYHCDWEGCGWKFARSDELTRHYRKHT 356
[Close]
BLAST of BTEB transcription factor vs. Ensembl Cavefish
Match: klf12b (Kruppel like factor 12 [Source:NCBI gene;Acc:103022763])

HSP 1 Score: 142.124 bits (357), Expect = 1.016e-39
Identity = 60/81 (74.07%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+EGC KVY K SHLKAH R HTGEKPY C W  C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H
Sbjct:  268 CDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWDGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRH 348
[Close]
BLAST of BTEB transcription factor vs. Ensembl Cavefish
Match: klf8 (Krueppel-like factor 8 [Source:NCBI gene;Acc:103040211])

HSP 1 Score: 140.969 bits (354), Expect = 2.975e-39
Identity = 57/81 (70.37%), Postives = 68/81 (83.95%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CDY+GC KVY K SHLKAH R+HTGEKPY C W  C W+FARSDELTRH+RKHTG +P++C  CD+SF+RSDHL LH+R+H
Sbjct:  265 CDYDGCNKVYTKSSHLKAHRRIHTGEKPYQCTWEGCTWRFARSDELTRHFRKHTGIKPFRCTDCDRSFSRSDHLALHRRRH 345
[Close]
BLAST of BTEB transcription factor vs. Ensembl Cavefish
Match: klf1 (Krueppel-like factor 1 [Source:NCBI gene;Acc:103029325])

HSP 1 Score: 139.043 bits (349), Expect = 1.834e-38
Identity = 58/86 (67.44%), Postives = 68/86 (79.07%), Query Frame = 2 
Query:  440 SMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHS 697
            +M  C Y GC K Y K SHLKAH R HTGEKPYSC+W  CGWKFARSDELTRHYRKHTG +PY+C  C ++F+RSDHL LH ++H+
Sbjct:  266 AMHCCSYPGCTKTYTKSSHLKAHLRTHTGEKPYSCSWDGCGWKFARSDELTRHYRKHTGLKPYECMLCQRAFSRSDHLALHMKRHA 351
[Close]
BLAST of BTEB transcription factor vs. Ensembl Sea Lamprey
Match: klf12b (Kruppel-like factor 12b [Source:ZFIN;Acc:ZDB-GENE-071004-22])

HSP 1 Score: 127.102 bits (318), Expect = 2.309e-37
Identity = 55/81 (67.90%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C+++GC KVY K SHLKAH R HTGEKPY C W  C WKFARSDELTRH+RKHTG +P+KC  C++SF+RSDHL LH+++H
Sbjct:   24 CEFDGCDKVYTKSSHLKAHMRTHTGEKPYRCTWDGCTWKFARSDELTRHFRKHTGVKPFKCVDCERSFSRSDHLALHRKRH 104
[Close]
BLAST of BTEB transcription factor vs. Ensembl Sea Lamprey
Match: KLF7 (Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC:6350])

HSP 1 Score: 133.265 bits (334), Expect = 2.614e-37
Identity = 60/116 (51.72%), Postives = 77/116 (66.38%), Query Frame = 2 
Query:  347 IDLILQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            +  + + +     K  R   + +  S  I + +  C + GC KVY K SHLKAH R HTGEKPY C+W  C W+FARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH ++H
Sbjct:  211 VATVAEAVAITVAKPCRVGGEAEGGSLEIKKRIHRCPFSGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCAHCDRSFSRSDHLALHMKRH 326
[Close]
BLAST of BTEB transcription factor vs. Ensembl Sea Lamprey
Match: KLF7 (Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC:6350])

HSP 1 Score: 127.102 bits (318), Expect = 3.260e-35
Identity = 56/82 (68.29%), Postives = 65/82 (79.27%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHT-GEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C + GC KVY K SHLKAH R HT GEKPY C+W  C W+FARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH ++H
Sbjct:  216 CPFSGCRKVYTKSSHLKAHQRTHTAGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCAHCDRSFSRSDHLALHMKRH 297

HSP 2 Score: 46.9802 bits (110), Expect = 1.718e-6
Identity = 22/63 (34.92%), Postives = 33/63 (52.38%), Query Frame = 2 
Query:  422 SNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKH 610
            ++   E  + C +EGC   + +   L  H+R HTG KP+ C    C   F+RSD L  H ++H
Sbjct:  237 THTAGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCA--HCDRSFSRSDHLALHMKRH 297
[Close]
BLAST of BTEB transcription factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003017.1 (pep scaffold:Pmarinus_7.0:GL484945:4078:4800:1 gene:ENSPMAG00000002754.1 transcript:ENSPMAT00000003017.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 119.398 bits (298), Expect = 1.019e-34
Identity = 54/82 (65.85%), Postives = 61/82 (74.39%), Query Frame = 2 
Query:  449 SCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            +C + GC K+Y K SHLKAH R HTGEKPY C W  C W+FARSDELTRH RKHTG RP+ C  CD+ FARSDHL LH + H
Sbjct:    3 ACTHPGCGKIYTKSSHLKAHVRTHTGEKPYVCPWSPCPWRFARSDELTRHVRKHTGARPFSCPDCDRRFARSDHLTLHAKTH 84

HSP 2 Score: 54.299 bits (129), Expect = 3.512e-10
Identity = 26/56 (46.43%), Postives = 33/56 (58.93%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C  P CG  + +S  L  H R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:    2 HACTHPGCGKIYTKSSHLKAHVRTHTGEKPYVCPWSPCPWRFARSDELTRHVRKHT 57
[Close]
BLAST of BTEB transcription factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000432.1 (pep scaffold:Pmarinus_7.0:GL477956:42837:43256:-1 gene:ENSPMAG00000000389.1 transcript:ENSPMAT00000000432.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 112.079 bits (279), Expect = 2.325e-31
Identity = 56/122 (45.90%), Postives = 69/122 (56.56%), Query Frame = 2 
Query:  356 ILQLIQERNQKFNR---PSCDIKRISNVIDES---MFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSES 703
            +L L Q   ++ +R   P+C     +  I  S     +C   GC K Y K SHL+AH R H GE+PY+C WP C  +F RSDEL RH R HTG+R + C  C K FARSDHL  H R H E 
Sbjct:    2 LLPLAQPSTRRCHRCRCPNCQTASNTATISSSSRRQHTCHVSGCGKAYGKTSHLRAHLRWHAGERPYACAWPLCARRFTRSDELRRHARTHTGERRFACVACGKRFARSDHLGKHARTHREG 123
[Close]
BLAST of BTEB transcription factor vs. Ensembl Yeast
Match: AZF1 (Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639])

HSP 1 Score: 74.7146 bits (182), Expect = 1.414e-15
Identity = 32/81 (39.51%), Postives = 48/81 (59.26%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C Y  C +++++ +HL+ H R H G KP+ C++  CG +F +   L  H R HTG++PY C  CDK F+R  +L  H   H
Sbjct:  595 CPY--CHRLFSQATHLEVHVRSHIGYKPFVCDY--CGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTH 671

HSP 2 Score: 65.0846 bits (157), Expect = 2.462e-12
Identity = 35/96 (36.46%), Postives = 53/96 (55.21%), Query Frame = 2 
Query:  446 FSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRK-HSESSTVLKIK 724
            F CDY  C K + +  +L+ H R+HTGEKPYSC+   C  KF+R   L  H   H   +P+ C+   C+K+F +  ++  H+ + H E+   L  K
Sbjct:  621 FVCDY--CGKRFTQGGNLRTHERLHTGEKPYSCDI--CDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFHKETLNALTAK 712
[Close]
BLAST of BTEB transcription factor vs. Ensembl Yeast
Match: MIG2 (Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced gene repression; under low glucose conditions relocalizes to mitochondrion, where it interacts with Ups1p, antagonizes mitochondrial fission factor Dnm1p, indicative of a role in mitochondrial fusion or regulating morphology; regulates filamentous growth in response to glucose depletion; activated in stochastic pulses of nuclear localization in response to low glucose [Source:SGD;Acc:S000003177])

HSP 1 Score: 72.0182 bits (175), Expect = 6.986e-15
Identity = 31/58 (53.45%), Postives = 38/58 (65.52%), Query Frame = 2 
Query:  446 FSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQ 619
            F CD   C + +++  H K H R HTGEKP+ C +P CG  F+RSDEL RH R HTGQ
Sbjct:   17 FRCDT--CHRGFHRLEHKKRHLRTHTGEKPHHCAFPGCGKSFSRSDELKRHMRTHTGQ 72

HSP 2 Score: 50.447 bits (119), Expect = 1.208e-7
Identity = 27/71 (38.03%), Postives = 39/71 (54.93%), Query Frame = 2 
Query:  500 KAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHSESS 706
            + +F V    +P+ C+   C   F R +   RH R HTG++P+ C +  C KSF+RSD L  H R H+  S
Sbjct:    5 QTNFPVDNENRPFRCDT--CHRGFHRLEHKKRHLRTHTGEKPHHCAFPGCGKSFSRSDELKRHMRTHTGQS 73
[Close]
BLAST of BTEB transcription factor vs. Ensembl Yeast
Match: ACE2 (Transcription factor required for septum destruction after cytokinesis; phosphorylation by Cbk1p blocks nuclear exit during M/G1 transition, causing localization to daughter cell nuclei, and also increases Ace2p activity; phosphorylation by Cdc28p and Pho85p prevents nuclear import during cell cycle phases other than cytokinesis; part of RAM network that regulates cellular polarity and morphogenesis; ACE2 has a paralog, SWI5, that arose from the whole genome duplication [Source:SGD;Acc:S000004121])

HSP 1 Score: 69.3218 bits (168), Expect = 8.416e-14
Identity = 32/98 (32.65%), Postives = 55/98 (56.12%), Query Frame = 2 
Query:  398 PSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRK 691
            P   I +    + + +F C Y  C KV+ +R ++++H + H  ++PYSC++P C   F R+ +L RH   H  ++ Y C  C K F R D L++H+ +
Sbjct:  587 PPGTIDQYVKELPDKLFECLYPNCNKVFKRRYNIRSHIQTHLQDRPYSCDFPGCTKAFVRNHDLIRHKISHNAKK-YICP-CGKRFNREDALMVHRSR 682
[Close]
BLAST of BTEB transcription factor vs. Ensembl Yeast
Match: FZF1 (Transcription factor involved in sulfite metabolism; sole identified regulatory target is SSU1; overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003223])

HSP 1 Score: 67.781 bits (164), Expect = 1.326e-13
Identity = 34/89 (38.20%), Postives = 45/89 (50.56%), Query Frame = 2 
Query:  446 FSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSESSTV 712
            + C ++GC KVYN+ S L+ H   HT +KPY C+ P CG KF R   L  H   H+  +P  C  C K F  +  L  H   H   S +
Sbjct:   12 YKCSFDGCEKVYNRPSLLQQHQNSHTNQKPYHCDEPGCGKKFIRPCHLRVHKWTHSQIKPKACTLCQKRFVTNQQLRRHLNSHERKSKL 100
[Close]
BLAST of BTEB transcription factor vs. Ensembl Yeast
Match: SWI5 (Transcription factor that recruits Mediator and Swi/Snf complexes; activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; required for expression of the HO gene controlling mating type switching; localization to nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase; SWI5 has a paralog, ACE2, that arose from the whole genome duplication [Source:SGD;Acc:S000002553])

HSP 1 Score: 68.5514 bits (166), Expect = 1.684e-13
Identity = 31/98 (31.63%), Postives = 54/98 (55.10%), Query Frame = 2 
Query:  398 PSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRK 691
            P   I +    + +  F C + GC K + +R ++++H + H  ++PYSC+ P C   F R+ +L RH + H  ++ Y C  C K F R D L++H+ +
Sbjct:  534 PRGSIDKYVKEMPDKTFECLFPGCTKTFKRRYNIRSHIQTHLEDRPYSCDHPGCDKAFVRNHDLIRHKKSHQ-EKAYACP-CGKKFNREDALVVHRSR 629

HSP 2 Score: 45.8246 bits (107), Expect = 4.532e-6
Identity = 22/60 (36.67%), Postives = 31/60 (51.67%), Query Frame = 2 
Query:  527 EKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQ--WCDKSFARSDHLLLHKRKHSE 700
            +K + C +P C   F R   +  H + H   RPY C    CDK+F R+  L+ HK+ H E
Sbjct:  547 DKTFECLFPGCTKTFKRRYNIRSHIQTHLEDRPYSCDHPGCDKAFVRNHDLIRHKKSHQE 606
[Close]
BLAST of BTEB transcription factor vs. Ensembl Nematostella
Match: EDO40451 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S780])

HSP 1 Score: 132.109 bits (331), Expect = 2.989e-39
Identity = 58/89 (65.17%), Postives = 69/89 (77.53%), Query Frame = 2 
Query:  428 VIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            +    +  CD+ GC KVY K SHLKAH R HTGEKPY CNW  C W+FARSDELTRH+RKHTG +P+KCQ CD++FARSDHL LH ++H
Sbjct:    8 LARRRIHHCDHPGCKKVYTKSSHLKAHIRTHTGEKPYKCNWEGCEWRFARSDELTRHFRKHTGAKPFKCQHCDRAFARSDHLALHMKRH 96

HSP 2 Score: 52.373 bits (124), Expect = 4.317e-9
Identity = 26/58 (44.83%), Postives = 35/58 (60.34%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHSES 703
            + C+ P C   + +S  L  H R HTG++PYKC W  C+  FARSD L  H RKH+ +
Sbjct:   14 HHCDHPGCKKVYTKSSHLKAHIRTHTGEKPYKCNWEGCEWRFARSDELTRHFRKHTGA 71

HSP 3 Score: 49.6766 bits (117), Expect = 4.912e-8
Identity = 26/67 (38.81%), Postives = 34/67 (50.75%), Query Frame = 2 
Query:  419 ISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQ 619
            I     E  + C++EGC   + +   L  HFR HTG KP+ C    C   FARSD L  H ++H  Q
Sbjct:   35 IRTHTGEKPYKCNWEGCEWRFARSDELTRHFRKHTGAKPFKCQ--HCDRAFARSDHLALHMKRHQPQ 99
[Close]
BLAST of BTEB transcription factor vs. Ensembl Nematostella
Match: EDO40483 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S781])

HSP 1 Score: 130.183 bits (326), Expect = 1.221e-38
Identity = 58/84 (69.05%), Postives = 67/84 (79.76%), Query Frame = 2 
Query:  443 MFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            +  CDYEGC KVY K SHLKAH R HTGEKPY C+W  C W+FARSDELTRHYRKHTG +P+KC  CD+ F+RSDHL LH ++H
Sbjct:    6 IHKCDYEGCTKVYTKSSHLKAHRRTHTGEKPYKCSWEGCSWRFARSDELTRHYRKHTGAKPFKCVHCDRCFSRSDHLSLHMKRH 89
[Close]
BLAST of BTEB transcription factor vs. Ensembl Nematostella
Match: EDO28599 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJE5])

HSP 1 Score: 127.872 bits (320), Expect = 1.132e-37
Identity = 58/81 (71.60%), Postives = 66/81 (81.48%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C +EGC K Y K SHLKAH R HTGEKPY CNW DC W+FARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH ++H
Sbjct:    5 CTFEGCNKSYTKSSHLKAHQRTHTGEKPYQCNWKDCLWRFARSDELTRHYRKHTGIKPFKCPTCDRSFSRSDHLSLHMKRH 85

HSP 2 Score: 48.9062 bits (115), Expect = 6.380e-8
Identity = 24/58 (41.38%), Postives = 33/58 (56.90%), Query Frame = 2 
Query:  530 KPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            + + C +  C   + +S  L  H R HTG++PY+C W  C   FARSD L  H RKH+
Sbjct:    1 RTHKCTFEGCNKSYTKSSHLKAHQRTHTGEKPYQCNWKDCLWRFARSDELTRHYRKHT 58
[Close]
BLAST of BTEB transcription factor vs. Ensembl Nematostella
Match: EDO48250 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJE5])

HSP 1 Score: 127.872 bits (320), Expect = 1.132e-37
Identity = 58/81 (71.60%), Postives = 66/81 (81.48%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            C +EGC K Y K SHLKAH R HTGEKPY CNW DC W+FARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH ++H
Sbjct:    5 CTFEGCNKSYTKSSHLKAHQRTHTGEKPYQCNWKDCLWRFARSDELTRHYRKHTGIKPFKCPTCDRSFSRSDHLSLHMKRH 85

HSP 2 Score: 48.9062 bits (115), Expect = 6.380e-8
Identity = 24/58 (41.38%), Postives = 33/58 (56.90%), Query Frame = 2 
Query:  530 KPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            + + C +  C   + +S  L  H R HTG++PY+C W  C   FARSD L  H RKH+
Sbjct:    1 RTHKCTFEGCNKSYTKSSHLKAHQRTHTGEKPYQCNWKDCLWRFARSDELTRHYRKHT 58
[Close]
BLAST of BTEB transcription factor vs. Ensembl Nematostella
Match: EDO30326 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T150])

HSP 1 Score: 128.642 bits (322), Expect = 2.730e-36
Identity = 55/82 (67.07%), Postives = 65/82 (79.27%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHS 697
            C + GC KVY K SHLKAH R HTGEKPY C+W  C W+FARSDELTRHYRKHTG +P+KC  CD+ F+RSDHL LH ++H+
Sbjct:  147 CQFSGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCNWRFARSDELTRHYRKHTGAKPFKCVHCDRCFSRSDHLALHMKRHA 228
[Close]
BLAST of BTEB transcription factor vs. Ensembl Medaka
Match: ENSORLT00000028981.1 (pep primary_assembly:ASM223467v1:1:30800576:30805289:1 gene:ENSORLG00000030426.1 transcript:ENSORLT00000028981.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 134.42 bits (337), Expect = 1.508e-39
Identity = 58/95 (61.05%), Postives = 72/95 (75.79%), Query Frame = 2 
Query:  413 KRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHS 697
            +R +     ++ SCDY GC K Y K SHLKAH R HTGEKPY C+W  C WKFARSDELTRH+RKHTGQ+PY+C  C ++F+RSDHL LH ++H+
Sbjct:   18 RRSTGKKRPAIHSCDYPGCTKTYTKSSHLKAHLRTHTGEKPYHCSWEGCSWKFARSDELTRHFRKHTGQKPYECLLCQRAFSRSDHLALHMKRHT 112
[Close]
BLAST of BTEB transcription factor vs. Ensembl Medaka
Match: klf4 (Kruppel like factor 4 [Source:NCBI gene;Acc:101163591])

HSP 1 Score: 142.895 bits (359), Expect = 2.451e-39
Identity = 66/110 (60.00%), Postives = 78/110 (70.91%), Query Frame = 2 
Query:  365 LIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            L +E   K  R S   KR++        +CDY GC K Y K SHLKAH R HTGEKPY C+W  CGWKFARSDELTRHYRKHTG RP++CQ CD++F+RSDHL LH ++H
Sbjct:  321 LPEEPKPKRGRRSWPRKRVAT------HTCDYVGCGKTYTKSSHLKAHHRTHTGEKPYHCDWEGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRH 424

HSP 2 Score: 56.9954 bits (136), Expect = 6.963e-9
Identity = 25/56 (44.64%), Postives = 35/56 (62.50%), Query Frame = 2 
Query:  536 YSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW--CDKSFARSDHLLLHKRKHS 697
            ++C++  CG  + +S  L  H+R HTG++PY C W  C   FARSD L  H RKH+
Sbjct:  342 HTCDYVGCGKTYTKSSHLKAHHRTHTGEKPYHCDWEGCGWKFARSDELTRHYRKHT 397
[Close]
BLAST of BTEB transcription factor vs. Ensembl Medaka
Match: klf8 (Krueppel-like factor 8 [Source:NCBI gene;Acc:101157477])

HSP 1 Score: 142.124 bits (357), Expect = 4.256e-39
Identity = 58/81 (71.60%), Postives = 68/81 (83.95%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CDYEGC KVY K SHLKAH R+HTGEKPY C W  C W+FARSDELTRH+RKHTG +P++C  CD+SF+RSDHL LH+R+H
Sbjct:  339 CDYEGCKKVYTKSSHLKAHRRIHTGEKPYHCTWEGCTWRFARSDELTRHFRKHTGIKPFRCTECDRSFSRSDHLSLHRRRH 419
[Close]
BLAST of BTEB transcription factor vs. Ensembl Medaka
Match: klf12b (Kruppel like factor 12 [Source:NCBI gene;Acc:101160517])

HSP 1 Score: 140.969 bits (354), Expect = 6.448e-39
Identity = 60/81 (74.07%), Postives = 67/81 (82.72%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CD+EGC KVY K SHLKAH R HTGEKPY C W  C WKFARSDELTRHYRKHTG +P+KC  CD+SF+RSDHL LH+R+H
Sbjct:  303 CDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWDGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRH 383
[Close]
BLAST of BTEB transcription factor vs. Ensembl Medaka
Match: klf8 (Krueppel-like factor 8 [Source:NCBI gene;Acc:101157477])

HSP 1 Score: 141.739 bits (356), Expect = 1.100e-38
Identity = 58/81 (71.60%), Postives = 68/81 (83.95%), Query Frame = 2 
Query:  452 CDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKH 694
            CDYEGC KVY K SHLKAH R+HTGEKPY C W  C W+FARSDELTRH+RKHTG +P++C  CD+SF+RSDHL LH+R+H
Sbjct:  381 CDYEGCKKVYTKSSHLKAHRRIHTGEKPYHCTWEGCTWRFARSDELTRHFRKHTGIKPFRCTECDRSFSRSDHLSLHRRRH 461
[Close]
BLAST of BTEB transcription factor vs. Planmine SMEST
Match: SMESG000032379.1 (SMESG000032379.1)

HSP 1 Score: 433.721 bits (1114), Expect = 3.904e-156
Identity = 208/208 (100.00%), Postives = 208/208 (100.00%), Query Frame = 2 
Query:  110 MTHFKPEEISEFSLMLPITPLYDDTSGCDDFSDYEHLLDYDFIIENTCQIRNDQNDFKFSRKEKDQRIFNVIPKLEMSQIDLILQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSESSTVLKIKKRN 733
            MTHFKPEEISEFSLMLPITPLYDDTSGCDDFSDYEHLLDYDFIIENTCQIRNDQNDFKFSRKEKDQRIFNVIPKLEMSQIDLILQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSESSTVLKIKKRN
Sbjct:    1 MTHFKPEEISEFSLMLPITPLYDDTSGCDDFSDYEHLLDYDFIIENTCQIRNDQNDFKFSRKEKDQRIFNVIPKLEMSQIDLILQLIQERNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSESSTVLKIKKRN 208
[Close]
BLAST of BTEB transcription factor vs. Planmine SMEST
Match: SMESG000025482.1 (SMESG000025482.1)

HSP 1 Score: 112.079 bits (279), Expect = 8.113e-30
Identity = 48/92 (52.17%), Postives = 61/92 (66.30%), Query Frame = 2 
Query:  431 IDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSESS 706
            + +  F C+Y+ C K Y K SHLKAH RVHTG+KPY CNW +C  +F RSDEL+RH R HTG++ + C  C + F RSDHL  H + H   S
Sbjct:  103 VRQKSFKCNYKSCLKAYYKSSHLKAHIRVHTGDKPYICNWENCQRRFTRSDELSRHKRTHTGEKLFSCSICQRKFNRSDHLSKHIKTHKNHS 194
[Close]
BLAST of BTEB transcription factor vs. Planmine SMEST
Match: SMESG000025482.1 (SMESG000025482.1)

HSP 1 Score: 111.694 bits (278), Expect = 9.864e-30
Identity = 48/92 (52.17%), Postives = 61/92 (66.30%), Query Frame = 2 
Query:  431 IDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSESS 706
            + +  F C+Y+ C K Y K SHLKAH RVHTG+KPY CNW +C  +F RSDEL+RH R HTG++ + C  C + F RSDHL  H + H   S
Sbjct:   89 VRQKSFKCNYKSCLKAYYKSSHLKAHIRVHTGDKPYICNWENCQRRFTRSDELSRHKRTHTGEKLFSCSICQRKFNRSDHLSKHIKTHKNHS 180
[Close]
BLAST of BTEB transcription factor vs. Planmine SMEST
Match: SMESG000050160.1 (SMESG000050160.1)

HSP 1 Score: 89.7373 bits (221), Expect = 3.518e-21
Identity = 44/103 (42.72%), Postives = 66/103 (64.08%), Query Frame = 2 
Query:  398 PSC-DIKRISNVIDES-MFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHKRKHSE 700
            P+C +++ +S  + ++   +C   GC K+Y+K SHLKAH R HTGE+P+ CNW  CG +F RSDEL +H + HT ++   C  C K F RS+ L  H + H++
Sbjct:  117 PNCQEMENLSGYLSKNNSHNCHIAGCGKLYSKPSHLKAHLRWHTGERPFVCNWLFCGKRFNRSDELQKHLKVHTDEKKLNCPKCGKHFVRSEQLSKHIQTHNK 219
[Close]
BLAST of BTEB transcription factor vs. Planmine SMEST
Match: SMESG000031008.1 (SMESG000031008.1)

HSP 1 Score: 89.3521 bits (220), Expect = 9.385e-21
Identity = 45/96 (46.88%), Postives = 58/96 (60.42%), Query Frame = 2 
Query:  413 KRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTGEKPYSCNW--PD---CGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLLLHK 685
            ++ S V     + C Y  C K Y K SHLKAH R+H+GEKP+ C +  PD   C   F RSD+LTRH R+H   +P++CQ C K F RSDH   H+
Sbjct:  166 RKSSIVSSPRSYKCSYLDCNKAYMKSSHLKAHMRIHSGEKPHICKYIFPDGTNCTESFVRSDQLTRHRRRHENDKPFQCQQCLKKFYRSDHCKTHQ 261

HSP 2 Score: 51.6026 bits (122), Expect = 1.833e-7
Identity = 26/79 (32.91%), Postives = 43/79 (54.43%), Query Frame = 2 
Query:  479 YNKRSHLKAHFRVHTGEKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQW-------CDKSFARSDHLLLHKRKH 694
            YN++S + +  R       Y C++ DC   + +S  L  H R H+G++P+ C++       C +SF RSD L  H+R+H
Sbjct:  164 YNRKSSIVSSPRS------YKCSYLDCNKAYMKSSHLKAHMRIHSGEKPHICKYIFPDGTNCTESFVRSDQLTRHRRRH 236
The following BLAST results are available for this feature:
BLAST of BTEB transcription factor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KLF42.957e-4059.09Kruppel like factor 4 [Source:HGNC Symbol;Acc:HGNC... [more]
KLF124.576e-3974.07Kruppel like factor 12 [Source:HGNC Symbol;Acc:HGN... [more]
KLF27.319e-3957.14Kruppel like factor 2 [Source:HGNC Symbol;Acc:HGNC... [more]
KLF41.063e-3871.95Kruppel like factor 4 [Source:HGNC Symbol;Acc:HGNC... [more]
KLF84.089e-3861.22Kruppel like factor 8 [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of BTEB transcription factor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
klf-32.790e-3666.27Kruppel-Like Factor (Zinc finger protein) [Source... [more]
klf-32.801e-3664.71Kruppel-Like Factor (Zinc finger protein) [Source... [more]
klf-19.341e-3667.90Kruppel-Like Factor (Zinc finger protein) [Source... [more]
klf-19.341e-3667.90Kruppel-Like Factor (Zinc finger protein) [Source... [more]
klf-21.841e-3566.67Kruppel-Like Factor (Zinc finger protein) [Source... [more]
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BLAST of BTEB transcription factor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dar16.453e-3956.90gene:FBgn0263239 transcript:FBtr0113134[more]
CG427412.084e-3671.60gene:FBgn0261705 transcript:FBtr0303203[more]
luna2.273e-3467.90gene:FBgn0040765 transcript:FBtr0345675[more]
luna2.273e-3467.90gene:FBgn0040765 transcript:FBtr0088210[more]
luna2.273e-3467.90gene:FBgn0040765 transcript:FBtr0333066[more]
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BLAST of BTEB transcription factor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
klf82.317e-3970.37Kruppel-like factor 8 [Source:ZFIN;Acc:ZDB-GENE-07... [more]
klf83.191e-3970.37Kruppel-like factor 8 [Source:ZFIN;Acc:ZDB-GENE-07... [more]
klf12a4.934e-3967.05Kruppel-like factor 12a [Source:ZFIN;Acc:ZDB-GENE-... [more]
klf12a4.934e-3967.05Kruppel-like factor 12a [Source:ZFIN;Acc:ZDB-GENE-... [more]
klf12a4.934e-3967.05Kruppel-like factor 12a [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of BTEB transcription factor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nudc2.388e-3974.07nudC nuclear distribution protein [Source:Xenbase;... [more]
klf48.191e-3970.73Kruppel-like factor 4 (gut) [Source:NCBI gene;Acc:... [more]
klf41.031e-3870.73Kruppel-like factor 4 (gut) [Source:NCBI gene;Acc:... [more]
KLF51.542e-3853.78Kruppel-like factor 5 (intestinal) [Source:NCBI ge... [more]
ica11.877e-3871.60islet cell autoantigen 1 [Source:Xenbase;Acc:XB-GE... [more]
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BLAST of BTEB transcription factor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Klf122.743e-3974.07Kruppel-like factor 12 [Source:MGI Symbol;Acc:MGI:... [more]
Klf122.743e-3974.07Kruppel-like factor 12 [Source:MGI Symbol;Acc:MGI:... [more]
Klf43.607e-3960.00Kruppel-like factor 4 (gut) [Source:MGI Symbol;Acc... [more]
Klf86.522e-3869.14Kruppel-like factor 8 [Source:MGI Symbol;Acc:MGI:2... [more]
Klf86.522e-3869.14Kruppel-like factor 8 [Source:MGI Symbol;Acc:MGI:2... [more]
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BLAST of BTEB transcription factor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O35738|KLF12_MOUSE1.918e-3874.07Krueppel-like factor 12 OS=Mus musculus OX=10090 G... [more]
sp|Q9Y4X4|KLF12_HUMAN2.197e-3874.07Krueppel-like factor 12 OS=Homo sapiens OX=9606 GN... [more]
sp|Q60793|KLF4_MOUSE2.523e-3860.00Krueppel-like factor 4 OS=Mus musculus OX=10090 GN... [more]
sp|Q9Y5W3|KLF2_HUMAN3.515e-3857.14Krueppel-like factor 2 OS=Homo sapiens OX=9606 GN=... [more]
sp|Q9VZN4|DAR1_DROME6.469e-3856.90Dendritic arbor reduction protein 1 OS=Drosophila ... [more]
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BLAST of BTEB transcription factor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A448XRW06.747e-4073.56Uncharacterized protein OS=Protopolystoma xenopodi... [more]
A0A085MCM77.050e-3938.76Uncharacterized protein OS=Trichuris suis OX=68888... [more]
A0A077Z1P29.989e-3944.05Zinc finger protein OS=Trichuris trichiura OX=3608... [more]
A0A183AAU51.242e-3841.76Uncharacterized protein OS=Echinostoma caproni OX=... [more]
T1JPZ21.774e-3868.48Uncharacterized protein OS=Tetranychus urticae OX=... [more]
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BLAST of BTEB transcription factor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000049113.12.620e-4051.97pep primary_assembly:Astyanax_mexicanus-2.0:16:543... [more]
ENSAMXT00000048628.19.002e-4060.91Kruppel like factor 4 [Source:NCBI gene;Acc:103040... [more]
klf12b1.016e-3974.07Kruppel like factor 12 [Source:NCBI gene;Acc:10302... [more]
klf82.975e-3970.37Krueppel-like factor 8 [Source:NCBI gene;Acc:10304... [more]
klf11.834e-3867.44Krueppel-like factor 1 [Source:NCBI gene;Acc:10302... [more]
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BLAST of BTEB transcription factor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
klf12b2.309e-3767.90Kruppel-like factor 12b [Source:ZFIN;Acc:ZDB-GENE-... [more]
KLF72.614e-3751.72Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC... [more]
KLF73.260e-3568.29Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC... [more]
ENSPMAT00000003017.11.019e-3465.85pep scaffold:Pmarinus_7.0:GL484945:4078:4800:1 gen... [more]
ENSPMAT00000000432.12.325e-3145.90pep scaffold:Pmarinus_7.0:GL477956:42837:43256:-1 ... [more]
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BLAST of BTEB transcription factor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
AZF11.414e-1539.51Zinc-finger transcription factor; involved in diau... [more]
MIG26.986e-1553.45Zinc finger transcriptional repressor; cooperates ... [more]
ACE28.416e-1432.65Transcription factor required for septum destructi... [more]
FZF11.326e-1338.20Transcription factor involved in sulfite metabolis... [more]
SWI51.684e-1331.63Transcription factor that recruits Mediator and Sw... [more]
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BLAST of BTEB transcription factor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO404512.989e-3965.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO404831.221e-3869.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO285991.132e-3771.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO482501.132e-3771.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO303262.730e-3667.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of BTEB transcription factor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000028981.11.508e-3961.05pep primary_assembly:ASM223467v1:1:30800576:308052... [more]
klf42.451e-3960.00Kruppel like factor 4 [Source:NCBI gene;Acc:101163... [more]
klf84.256e-3971.60Krueppel-like factor 8 [Source:NCBI gene;Acc:10115... [more]
klf12b6.448e-3974.07Kruppel like factor 12 [Source:NCBI gene;Acc:10116... [more]
klf81.100e-3871.60Krueppel-like factor 8 [Source:NCBI gene;Acc:10115... [more]
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BLAST of BTEB transcription factor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000032379.13.904e-156100.00SMESG000032379.1[more]
SMESG000025482.18.113e-3052.17SMESG000025482.1[more]
SMESG000025482.19.864e-3052.17SMESG000025482.1[more]
SMESG000050160.13.518e-2142.72SMESG000050160.1[more]
SMESG000031008.19.385e-2146.88SMESG000031008.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033868 ID=SMED30033868|Name=BTEB transcription factor|organism=Schmidtea mediterranea sexual|type=transcript|length=843bp
TATAAATCTTATATGGATTCTATAAATAGACCTGAATATTTAACCAATTA
AATGAAGTGCCAATAGCAGTAAGCCAATGGTATTGCTTTATATTTTTCAA
TCTACATTAATGACACATTTTAAACCTGAAGAAATTTCTGAATTTTCGTT
AATGCTTCCTATAACTCCTTTATATGACGATACAAGTGGATGTGATGATT
TTTCAGATTACGAGCATTTATTGGATTATGATTTTATTATTGAAAATACT
TGTCAAATTAGAAATGATCAAAACGATTTCAAATTTTCCAGAAAAGAAAA
AGATCAAAGAATTTTTAATGTCATTCCAAAGTTGGAAATGTCACAAATCG
ATCTAATTTTACAACTGATCCAGGAAAGAAATCAAAAATTTAATAGACCA
TCCTGCGATATCAAACGAATATCCAATGTTATTGACGAGTCAATGTTTTC
TTGCGATTATGAAGGTTGTTTTAAAGTTTACAACAAACGATCCCATTTAA
AAGCTCATTTTCGCGTACATACTGGCGAAAAGCCTTACAGTTGCAATTGG
CCAGATTGCGGTTGGAAATTTGCCAGATCAGATGAACTGACGAGACATTA
TAGAAAACACACTGGCCAACGTCCTTATAAATGCCAGTGGTGTGACAAGA
GTTTCGCTCGAAGTGATCATTTGCTACTTCATAAAAGAAAACATTCCGAA
TCGTCTACAGTGTTGAAAATTAAAAAGCGCAATTAATATATAATGACTAC
ATATAAGTCTTTCAAATAGAAATCTCAGGTTTCTGAATGGATTGAGATTA
TTCTTCACATGAAATCACATATCAGAAACCTTTATCATATCAC
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protein sequence of SMED30033868-orf-1

>SMED30033868-orf-1 ID=SMED30033868-orf-1|Name=SMED30033868-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=220bp
MVLLYIFQSTLMTHFKPEEISEFSLMLPITPLYDDTSGCDDFSDYEHLLD
YDFIIENTCQIRNDQNDFKFSRKEKDQRIFNVIPKLEMSQIDLILQLIQE
RNQKFNRPSCDIKRISNVIDESMFSCDYEGCFKVYNKRSHLKAHFRVHTG
EKPYSCNWPDCGWKFARSDELTRHYRKHTGQRPYKCQWCDKSFARSDHLL
LHKRKHSESSTVLKIKKRN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR036236Znf_C2H2_sf
IPR015880Znf_C2H2-like
IPR013087Znf_C2H2_type
IPR007087Znf_C2H2
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0046872metal ion binding
GO:0000975regulatory region DNA binding
GO:0000987core promoter proximal region sequence-specific DNA binding
GO:0001010transcription factor activity, sequence-specific DNA binding transcription factor recruiting
GO:0001047core promoter binding
GO:0001077transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085RNA polymerase II transcription factor binding
GO:0001190transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001221transcription cofactor binding
GO:0003677DNA binding
GO:0003690double-stranded DNA binding
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0008013beta-catenin binding
GO:0008134transcription factor binding
GO:0035014phosphatidylinositol 3-kinase regulator activity
GO:0042826histone deacetylase binding
GO:0043565sequence-specific DNA binding
GO:0044212transcription regulatory region DNA binding
Vocabulary: biological process
TermDefinition
GO:0010629negative regulation of gene expression
GO:0000122negative regulation of transcription from RNA polymerase II promoter
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0006357regulation of transcription from RNA polymerase II promoter
GO:0006366transcription from RNA polymerase II promoter
GO:0008285negative regulation of cell proliferation
GO:0009913epidermal cell differentiation
GO:0010033response to organic substance
GO:0010628positive regulation of gene expression
GO:0014067negative regulation of phosphatidylinositol 3-kinase signaling
GO:0014740negative regulation of muscle hyperplasia
GO:0019827stem cell population maintenance
GO:0030154cell differentiation
GO:0030336negative regulation of cell migration
GO:0031077post-embryonic camera-type eye development
GO:0032088negative regulation of NF-kappaB transcription factor activity
GO:0032270positive regulation of cellular protein metabolic process
GO:0032526response to retinoic acid
GO:0034115negative regulation of heterotypic cell-cell adhesion
GO:0035166post-embryonic hemopoiesis
GO:0042127regulation of cell proliferation
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043551regulation of phosphatidylinositol 3-kinase activity
GO:0045415negative regulation of interleukin-8 biosynthetic process
GO:0045429positive regulation of nitric oxide biosynthetic process
GO:0045444fat cell differentiation
GO:0045595regulation of cell differentiation
GO:0045892negative regulation of transcription, DNA-templated
GO:0045893positive regulation of transcription, DNA-templated
GO:0045944positive regulation of transcription from RNA polymerase II promoter
GO:0046985positive regulation of hemoglobin biosynthetic process
GO:0048662negative regulation of smooth muscle cell proliferation
GO:0048679regulation of axon regeneration
GO:0048730epidermis morphogenesis
GO:0051247positive regulation of protein metabolic process
GO:0051898negative regulation of protein kinase B signaling
GO:0051973positive regulation of telomerase activity
GO:0060070canonical Wnt signaling pathway
GO:0060761negative regulation of response to cytokine stimulus
GO:0070301cellular response to hydrogen peroxide
GO:0070373negative regulation of ERK1 and ERK2 cascade
GO:0071300cellular response to retinoic acid
GO:0071363cellular response to growth factor stimulus
GO:0071407cellular response to organic cyclic compound
GO:0071409cellular response to cycloheximide
GO:0071499cellular response to laminar fluid shear stress
GO:0090051negative regulation of cell migration involved in sprouting angiogenesis
GO:1901653cellular response to peptide
GO:1904798positive regulation of core promoter binding
GO:1904998negative regulation of leukocyte adhesion to arterial endothelial cell
GO:2000342negative regulation of chemokine (C-X-C motif) ligand 2 production
Vocabulary: cellular component
TermDefinition
GO:0000785chromatin
GO:0000790nuclear chromatin
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005667transcription factor complex
GO:0005719nuclear euchromatin
GO:0005737cytoplasm
GO:0044798nuclear transcription factor complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013087Zinc finger C2H2-typeSMARTSM00355c2h2final6coord: 154..178
e-value: 8.7E-5
score: 31.9
coord: 124..148
e-value: 0.034
score: 23.3
coord: 184..206
e-value: 3.7E-4
score: 29.8
IPR013087Zinc finger C2H2-typePFAMPF00096zf-C2H2coord: 124..148
e-value: 0.013
score: 15.9
coord: 154..178
e-value: 7.4E-6
score: 26.1
coord: 184..206
e-value: 2.1E-5
score: 24.7
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 156..178
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 126..148
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 186..206
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 124..153
score: 14.815
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 184..211
score: 12.424
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 154..183
score: 15.396
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 178..208
e-value: 3.2E-12
score: 48.2
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 111..151
e-value: 1.3E-10
score: 42.9
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 152..177
e-value: 6.6E-15
score: 56.6
NoneNo IPR availablePANTHERPTHR23235TRANSCRIPTION FACTOR SP3coord: 110..206
NoneNo IPR availablePANTHERPTHR23235:SF90KRUEPPEL-LIKE FACTOR LUNAcoord: 110..206
IPR036236Zinc finger C2H2 superfamilySUPERFAMILYSSF57667beta-beta-alpha zinc fingerscoord: 171..207
IPR036236Zinc finger C2H2 superfamilySUPERFAMILYSSF57667beta-beta-alpha zinc fingerscoord: 139..182