synaptotagmin-14 isoform X1

Overview
Namesynaptotagmin-14 isoform X1
Smed IDSMED30033835
Length (bp)1982
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of synaptotagmin-14 isoform X1 (SMED30033835) t-SNE clustered cells

Violin plots show distribution of expression levels for synaptotagmin-14 isoform X1 (SMED30033835) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of synaptotagmin-14 isoform X1 (SMED30033835) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for synaptotagmin-14 isoform X1 (SMED30033835) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033835

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30033835h1SMcG0019451 dd_Smed_v4_8785_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30033835h1SMcG0019451 dd_Smed_v4_8785_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30033835h1SMcG0019451 dd_Smed_v4_8785_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30033835h1SMcG0019451 dd_Smed_v4_8785_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30033835h1SMcG0019451 OX_Smed_1.0.16802ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Human
Match: SYT14 (synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:23143])

HSP 1 Score: 155.221 bits (391), Expect = 5.934e-40
Identity = 104/348 (29.89%), Postives = 173/348 (49.71%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  ++ +  +   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  190 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCDSQMSVSEMSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 514
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Human
Match: SYT14 (synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:23143])

HSP 1 Score: 155.221 bits (391), Expect = 5.934e-40
Identity = 104/348 (29.89%), Postives = 173/348 (49.71%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  ++ +  +   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  190 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCDSQMSVSEMSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 514
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Human
Match: SYT14 (synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:23143])

HSP 1 Score: 154.836 bits (390), Expect = 1.335e-39
Identity = 104/348 (29.89%), Postives = 173/348 (49.71%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  ++ +  +   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  228 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCDSQMSVSEMSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 552
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Human
Match: SYT14 (synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:23143])

HSP 1 Score: 144.821 bits (364), Expect = 4.783e-36
Identity = 118/426 (27.70%), Postives = 196/426 (46.01%), Query Frame = 1 
Query:  493 QDDLQPEHQS-ENSYHGETQGDESHSWNPKSEQFNNDENEDA-----QTLDDNTYS---PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLP-------------------DTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            QDD    H S   S  G+++ + SH  N     +N   +E +     ++  +  Y    P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  ++ +  +   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P                   DT++KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  169 QDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCDSQMSVSEMSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 571
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Human
Match: SYT14 (synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:23143])

HSP 1 Score: 145.206 bits (365), Expect = 5.651e-36
Identity = 118/426 (27.70%), Postives = 196/426 (46.01%), Query Frame = 1 
Query:  493 QDDLQPEHQS-ENSYHGETQGDESHSWNPKSEQFNNDENEDA-----QTLDDNTYS---PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLP-------------------DTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            QDD    H S   S  G+++ + SH  N     +N   +E +     ++  +  Y    P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  ++ +  +   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P                   DT++KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  214 QDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCDSQMSVSEMSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 616
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Fly
Match: Syt14 (gene:FBgn0261086 transcript:FBtr0336485)

HSP 1 Score: 131.724 bits (330), Expect = 5.496e-32
Identity = 88/265 (33.21%), Postives = 141/265 (53.21%), Query Frame = 1 
Query:  877 IHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEK--NSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEET--AKTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            + +L++  KK + KTK+R G +P + E+  + ++N E+     LR RLYG  R    ++IGE ++    VD++  ++ ++ L      + P   ++ + +T      + SL  +E   ++  ++ G + EL +GL++N  TGRL+V I +G+    L  NK PDT++K+++  S G+E   AKT + +   NP F E F+FQV  FQL+D  L I  Y     KK  M G FSLG      E   HW D+     GE + RWH  
Sbjct:  330 VRMLMLPSKKQKLKTKIRSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLE--LETNLWL-----PLEPRNTSSGLGST----SDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVL 583
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Fly
Match: Syt14 (gene:FBgn0261086 transcript:FBtr0078957)

HSP 1 Score: 131.724 bits (330), Expect = 5.496e-32
Identity = 88/265 (33.21%), Postives = 141/265 (53.21%), Query Frame = 1 
Query:  877 IHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEK--NSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEET--AKTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            + +L++  KK + KTK+R G +P + E+  + ++N E+     LR RLYG  R    ++IGE ++    VD++  ++ ++ L      + P   ++ + +T      + SL  +E   ++  ++ G + EL +GL++N  TGRL+V I +G+    L  NK PDT++K+++  S G+E   AKT + +   NP F E F+FQV  FQL+D  L I  Y     KK  M G FSLG      E   HW D+     GE + RWH  
Sbjct:  330 VRMLMLPSKKQKLKTKIRSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLE--LETNLWL-----PLEPRNTSSGLGST----SDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVL 583
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Fly
Match: Syt14 (gene:FBgn0261086 transcript:FBtr0339551)

HSP 1 Score: 132.109 bits (331), Expect = 7.492e-32
Identity = 88/265 (33.21%), Postives = 141/265 (53.21%), Query Frame = 1 
Query:  877 IHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEK--NSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEET--AKTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            + +L++  KK + KTK+R G +P + E+  + ++N E+     LR RLYG  R    ++IGE ++    VD++  ++ ++ L      + P   ++ + +T      + SL  +E   ++  ++ G + EL +GL++N  TGRL+V I +G+    L  NK PDT++K+++  S G+E   AKT + +   NP F E F+FQV  FQL+D  L I  Y     KK  M G FSLG      E   HW D+     GE + RWH  
Sbjct:  330 VRMLMLPSKKQKLKTKIRSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLE--LETNLWL-----PLEPRNTSSGLGST----SDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVL 583
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Fly
Match: Syt4 (gene:FBgn0028400 transcript:FBtr0081578)

HSP 1 Score: 58.9214 bits (141), Expect = 8.228e-9
Identity = 60/257 (23.35%), Postives = 108/257 (42.02%), Query Frame = 1 
Query:  718 KCGDVRIKIGLDSEKLTLIMTVLLAHDYA--RPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKM-RQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQV 1473
            K G +  K+   +E+  L+++++          SS T  I     G   A     + + ++  K+H+ KT++ R   +P ++E      +N  + +   L F +    R +   VIGE   PL  ++I               G    E  ++ K               +  SL + +    EL + L +    GRLTV + +  NLP++    L D ++K+ L +  G+  A  KT V K + +P F+E F+F +
Sbjct:  179 KLGTIYFKLRYLAERNALMVSIIRCRGLPCKGGSSGTGDIPTGMNGRTQAATDPYVKLQLLPDKQHKVKTRVVRNTRNPVYDEDFTFYGLNMNDLQNMSLHFVILSFDRYSRDDVIGEVVCPLTSIEI---------------GDISKEALSISK-------------EIQPRSLKIRAQGRGELLISLCWQPAAGRLTVVLLKARNLPRMDVTGLADPYVKIYL-LYNGQRIAKKKTHVKKRTLSPVFNESFAFDI 406
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Zebrafish
Match: syt14a (synaptotagmin XIVa [Source:ZFIN;Acc:ZDB-GENE-090313-200])

HSP 1 Score: 145.206 bits (365), Expect = 1.427e-36
Identity = 106/345 (30.72%), Postives = 167/345 (48.41%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDY----ARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +L+   S +++ +          G D E L    T+ +  DY     R S S  ++ + P+      +++ +H++++  KK R KT +++GP P F ET   + I  E    + +RFRLY   R    + +GE    L K+++  KM   I+L   DP       ++    +   C    S   +         GS PE+ +GL +N  TGRL+V + +G++   L  NK P+T++KL L  S G+E +  KT V +   NPT+ E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW ++  SK G+++ RWH+ 
Sbjct:  216 PSDSTAVLSPEDLSARGSAAQLPK----------GYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIIL---DPYCNIPGSDSQASMSDVSCSETASSYPSAAQ------GSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESK-GQQVCRWHSL 540
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Zebrafish
Match: syt14a (synaptotagmin XIVa [Source:ZFIN;Acc:ZDB-GENE-090313-200])

HSP 1 Score: 135.961 bits (341), Expect = 1.368e-33
Identity = 107/364 (29.40%), Postives = 167/364 (45.88%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDY----ARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLP-------------------DTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +L+   S +++ +          G D E L    T+ +  DY     R S S  ++ + P+      +++ +H++++  KK R KT +++GP P F ET   + I  E    + +RFRLY   R    + +GE    L K+++  KM   I+L   DP       ++    +   C    S   +         GS PE+ +GL +N  TGRL+V + +G++   L  NK P                   DT++KL L  S G+E +  KT V +   NPT+ E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW ++  SK G+++ RWH+ 
Sbjct:  154 PSDSTAVLSPEDLSARGSAAQLPK----------GYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIIL---DPYCNIPGSDSQASMSDVSCSETASSYPSAAQ------GSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESK-GQQVCRWHSL 497
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Zebrafish
Match: syt14b (synaptotagmin XIVb [Source:ZFIN;Acc:ZDB-GENE-041014-36])

HSP 1 Score: 134.806 bits (338), Expect = 4.203e-33
Identity = 96/313 (30.67%), Postives = 162/313 (51.76%), Query Frame = 1 
Query:  757 EKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAV-----LAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIA-PNEMNTLIKATYCKCDSITSLVSTEKNSLFLES---GSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGY-QXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            E L    T+ +A +Y  P    L++      ++P +     +++ +H++++  KK R KT +++GP P F ET + + + ++    + +RFRLY   R    +V+GE    L K+++  K+    L +T +PG + P             C S+ S VS    +L   S    S+PEL +GL +N  TGRL+  + +G++      +KLP+T++KL +  SKG+E +  KT V +   NPT+ E F FQV  FQL +  L +  Y +    K++   G  +LG     EE+E HW  +  S+ G+++  WHT 
Sbjct:  232 EALGKYGTLDVAFEY-DPGEQRLAVTVTAATDIPTLKSTGNISWQVHLVLLPTKKQRAKTGVQKGPCPVFTETFRFSCVEEDALGDYAVRFRLYSVRRMKKEKVLGEKVFYLTKLNLQGKL---ALPVTLEPGTSVPG------------CGSVVS-VSRSAGALSCRSTGESSIPELLLGLLYNSTTGRLSAEVIKGSHFKNSASDKLPNTYVKLTMLDSKGKEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSEVTLQVSVYSRRSSMKRRERVGWVALGLNSTTEEQEEHWTQMKESE-GQQVCHWHTL 526
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Zebrafish
Match: syt14a (synaptotagmin XIVa [Source:ZFIN;Acc:ZDB-GENE-090313-200])

HSP 1 Score: 135.191 bits (339), Expect = 5.034e-33
Identity = 107/364 (29.40%), Postives = 167/364 (45.88%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDY----ARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLP-------------------DTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +L+   S +++ +          G D E L    T+ +  DY     R S S  ++ + P+      +++ +H++++  KK R KT +++GP P F ET   + I  E    + +RFRLY   R    + +GE    L K+++  KM   I+L   DP       ++    +   C    S   +         GS PE+ +GL +N  TGRL+V + +G++   L  NK P                   DT++KL L  S G+E +  KT V +   NPT+ E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW ++  SK G+++ RWH+ 
Sbjct:  214 PSDSTAVLSPEDLSARGSAAQLPK----------GYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIIL---DPYCNIPGSDSQASMSDVSCSETASSYPSAAQ------GSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESK-GQQVCRWHSL 557
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Zebrafish
Match: syt14a (synaptotagmin XIVa [Source:ZFIN;Acc:ZDB-GENE-090313-200])

HSP 1 Score: 135.191 bits (339), Expect = 6.136e-33
Identity = 107/364 (29.40%), Postives = 167/364 (45.88%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDY----ARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLP-------------------DTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +L+   S +++ +          G D E L    T+ +  DY     R S S  ++ + P+      +++ +H++++  KK R KT +++GP P F ET   + I  E    + +RFRLY   R    + +GE    L K+++  KM   I+L   DP       ++    +   C    S   +         GS PE+ +GL +N  TGRL+V + +G++   L  NK P                   DT++KL L  S G+E +  KT V +   NPT+ E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW ++  SK G+++ RWH+ 
Sbjct:  231 PSDSTAVLSPEDLSARGSAAQLPK----------GYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIIL---DPYCNIPGSDSQASMSDVSCSETASSYPSAAQ------GSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESK-GQQVCRWHSL 574
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Xenopus
Match: SYT14 (synaptotagmin 14 [Source:NCBI gene;Acc:100491102])

HSP 1 Score: 142.895 bits (359), Expect = 8.758e-36
Identity = 103/362 (28.45%), Postives = 182/362 (50.28%), Query Frame = 1 
Query:  610 DAQTLDDNTYS---PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            +A++  +  Y    P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D             + TGN  +   + +H++++ VKK R KT +++GP P F ET K   I  E    + +RFRLY   R    +++GE    L K+++  K+   ++L   +P  + +  ++ +  +   C   TS   +      L  GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +  +NP + E F FQV  FQL +  L +  Y     K+K + G  SLG     +E+ +HW ++  SK G+++ RWHT 
Sbjct:  164 EAESFQNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKSFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDLPT---------HNRTGNNNS---WQVHLVLLPVKKQRAKTAVQRGPCPAFTETFKFNHIESEMIANYAVRFRLYLVRRMKKERMVGEKIFYLTKLNLQGKLSLPVVL---EPAYSLSGCDSQMSMSEMSCTESTSSCQS------LVHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLSANRPPNTYVKLTLMNSMGQEMSKCKTSIRRGQSNPLYKETFIFQVALFQLSEVTLILSVYNKRSMKRKELIGWISLGLNSSGDEQLNHWTEMKESK-GQQVCRWHTL 503
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Xenopus
Match: SYT14 (synaptotagmin 14 [Source:NCBI gene;Acc:100491102])

HSP 1 Score: 142.895 bits (359), Expect = 1.110e-35
Identity = 103/362 (28.45%), Postives = 182/362 (50.28%), Query Frame = 1 
Query:  610 DAQTLDDNTYS---PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            +A++  +  Y    P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D             + TGN  +   + +H++++ VKK R KT +++GP P F ET K   I  E    + +RFRLY   R    +++GE    L K+++  K+   ++L   +P  + +  ++ +  +   C   TS   +      L  GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +  +NP + E F FQV  FQL +  L +  Y     K+K + G  SLG     +E+ +HW ++  SK G+++ RWHT 
Sbjct:  188 EAESFQNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKSFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDLPT---------HNRTGNNNS---WQVHLVLLPVKKQRAKTAVQRGPCPAFTETFKFNHIESEMIANYAVRFRLYLVRRMKKERMVGEKIFYLTKLNLQGKLSLPVVL---EPAYSLSGCDSQMSMSEMSCTESTSSCQS------LVHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLSANRPPNTYVKLTLMNSMGQEMSKCKTSIRRGQSNPLYKETFIFQVALFQLSEVTLILSVYNKRSMKRKELIGWISLGLNSSGDEQLNHWTEMKESK-GQQVCRWHTL 527
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Xenopus
Match: SYT14 (synaptotagmin 14 [Source:NCBI gene;Acc:100491102])

HSP 1 Score: 142.51 bits (358), Expect = 1.759e-35
Identity = 103/362 (28.45%), Postives = 182/362 (50.28%), Query Frame = 1 
Query:  610 DAQTLDDNTYS---PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            +A++  +  Y    P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D             + TGN  +   + +H++++ VKK R KT +++GP P F ET K   I  E    + +RFRLY   R    +++GE    L K+++  K+   ++L   +P  + +  ++ +  +   C   TS   +      L  GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +  +NP + E F FQV  FQL +  L +  Y     K+K + G  SLG     +E+ +HW ++  SK G+++ RWHT 
Sbjct:  204 EAESFQNKGYEEDVPSDSTAVLSPEDMSARGSSSQLPKSFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDLPT---------HNRTGNNNS---WQVHLVLLPVKKQRAKTAVQRGPCPAFTETFKFNHIESEMIANYAVRFRLYLVRRMKKERMVGEKIFYLTKLNLQGKLSLPVVL---EPAYSLSGCDSQMSMSEMSCTESTSSCQS------LVHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLSANRPPNTYVKLTLMNSMGQEMSKCKTSIRRGQSNPLYKETFIFQVALFQLSEVTLILSVYNKRSMKRKELIGWISLGLNSSGDEQLNHWTEMKESK-GQQVCRWHTL 543
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Xenopus
Match: SYT14 (synaptotagmin 14 [Source:NCBI gene;Acc:100491102])

HSP 1 Score: 144.05 bits (362), Expect = 3.044e-35
Identity = 102/348 (29.31%), Postives = 178/348 (51.15%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D   P+        + TGN  +   + +H++++ VKK R KT +++GP P F ET K   I  E    + +RFRLY   R    +++GE    L K+++  K+   ++L   +P  + +  ++ +  +   C   TS   +      L  GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +  +NP + E F FQV  FQL +  L +  Y     K+K + G  SLG     +E+ +HW ++  SK G+++ RWHT 
Sbjct:  465 PSDSTAVLSPEDMSARGSSSQLPKSFDPEPVAKYGTLDVTFDYDSQEQKLLVTVTAVTDL--PT-------HNRTGNNNS---WQVHLVLLPVKKQRAKTAVQRGPCPAFTETFKFNHIESEMIANYAVRFRLYLVRRMKKERMVGEKIFYLTKLNLQGKLSLPVVL---EPAYSLSGCDSQMSMSEMSCTESTSSCQS------LVHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLSANRPPNTYVKLTLMNSMGQEMSKCKTSIRRGQSNPLYKETFIFQVALFQLSEVTLILSVYNKRSMKRKELIGWISLGLNSSGDEQLNHWTEMKESK-GQQVCRWHTL 790
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Xenopus
Match: tjp1 (tight junction protein 1 [Source:Xenbase;Acc:XB-GENE-490684])

HSP 1 Score: 60.4622 bits (145), Expect = 1.467e-10
Identity = 46/116 (39.66%), Postives = 62/116 (53.45%), Query Frame = 1 
Query: 1318 RGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            +G++   L  N+ PDT+ KL L  S G E +  KT V +   NP + E F FQV  FQL D  L I  Y     K+K M G  SLG     EE ++HW ++  SK G+++  WHT 
Sbjct:    3 KGSHFRNLAINRPPDTYGKLSLLDSVGHEISRCKTSVRRGQPNPVYKETFIFQVALFQLTDFTLMISIYNRRSMKRKEMIGWISLGKNSSGEEEQNHWLEMKESK-GQQVCHWHTL 117
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Mouse
Match: Syt14 (synaptotagmin XIV [Source:MGI Symbol;Acc:MGI:2444490])

HSP 1 Score: 159.844 bits (403), Expect = 2.144e-41
Identity = 119/407 (29.24%), Postives = 192/407 (47.17%), Query Frame = 1 
Query:  493 QDDLQPEHQS-ENSYHGETQGDESHSWNPKSEQFNNDENEDAQTLDDNTYS--------PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            QDD    H S   S  G+ + + SH  N     FN   +E +   +  +Y         P+D    +S  +++   S S++ +        K G + +    DSE+  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P   P+  ++ +  +   C   TS   +      L+ GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT   +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW  +  SK G+++ RWH  
Sbjct:  169 QDDSGSPHLSCTPSEIGDAKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSERQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNPSGCDSQVSLSEASCGDSTSSCQS------LQHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNRRSMKRKEMIGWISLGLNSSGEEELRHWTAMKESK-GQQVCRWHAL 552
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Mouse
Match: Syt14 (synaptotagmin XIV [Source:MGI Symbol;Acc:MGI:2444490])

HSP 1 Score: 160.229 bits (404), Expect = 1.201e-40
Identity = 120/407 (29.48%), Postives = 194/407 (47.67%), Query Frame = 1 
Query:  493 QDDLQPEHQS-ENSYHGETQGDESHSWNPKSEQFNNDENE-----DAQTLDDNTYS---PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            QDD    H S   S  G+ + + SH  N     FN   +E     +A++  +  Y    P+D    +S  +++   S S++ +        K G + +    DSE+  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P   P+  ++ +  +   C   TS   +      L+ GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT   +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW  +  SK G+++ RWH  
Sbjct:  452 QDDSGSPHLSCTPSEIGDAKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSERQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNPSGCDSQVSLSEASCGDSTSSCQS------LQHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNRRSMKRKEMIGWISLGLNSSGEEELRHWTAMKESK-GQQVCRWHAL 835
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Mouse
Match: Syt14 (synaptotagmin XIV [Source:MGI Symbol;Acc:MGI:2444490])

HSP 1 Score: 149.443 bits (376), Expect = 8.644e-38
Identity = 120/426 (28.17%), Postives = 192/426 (45.07%), Query Frame = 1 
Query:  493 QDDLQPEHQS-ENSYHGETQGDESHSWNPKSEQFNNDENEDAQTLDDNTYS--------PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLP-------------------DTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            QDD    H S   S  G+ + + SH  N     FN   +E +   +  +Y         P+D    +S  +++   S S++ +        K G + +    DSE+  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P   P+  ++ +  +   C   TS   +      L+ GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P                   DT++KL L  S G+E +  KT   +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW  +  SK G+++ RWH  
Sbjct:  169 QDDSGSPHLSCTPSEIGDAKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSERQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNPSGCDSQVSLSEASCGDSTSSCQS------LQHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNRRSMKRKEMIGWISLGLNSSGEEELRHWTAMKESK-GQQVCRWHAL 571
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Mouse
Match: Syt16 (synaptotagmin XVI [Source:MGI Symbol;Acc:MGI:2673872])

HSP 1 Score: 126.716 bits (317), Expect = 5.841e-30
Identity = 79/269 (29.37%), Postives = 133/269 (49.44%), Query Frame = 1 
Query:  718 KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGY 1518
            KCGD+ +     +    L +T++ A                P  +   V ++ +H++++  KK R KT +++GP+P F E +  TK+   +     +RFRLY + +    +++GE    L  +  + +M+  ++L  +   ++  E + L  +     DS +S  S       L  G +PEL VGL++N  TGRL+V + +G++   L  N+ PDT+ KL L    G+E +  KT + +   NP + E F FQV  FQL D  L I  Y
Sbjct:  344 KCGDLDVIFEYRAVTQKLTVTIVRAQGL-------------PDKDRSGVNSWQVHIVLLPSKKQRGKTNIQRGPNPVFKEKVTFTKLEPRDVASCAVRFRLYAARKMTRERMMGEKLFCLSHLHPEGEMKVTLVLEPRS-NLSSGE-SPLSPSVVSHSDSASSTQS-------LSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAANRAPDTYGKLFLLNCVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISIY 590
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Mouse
Match: Syt16 (synaptotagmin XVI [Source:MGI Symbol;Acc:MGI:2673872])

HSP 1 Score: 124.405 bits (311), Expect = 1.603e-29
Identity = 79/269 (29.37%), Postives = 133/269 (49.44%), Query Frame = 1 
Query:  718 KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGY 1518
            KCGD+ +     +    L +T++ A                P  +   V ++ +H++++  KK R KT +++GP+P F E +  TK+   +     +RFRLY + +    +++GE    L  +  + +M+  ++L  +   ++  E + L  +     DS +S  S       L  G +PEL VGL++N  TGRL+V + +G++   L  N+ PDT+ KL L    G+E +  KT + +   NP + E F FQV  FQL D  L I  Y
Sbjct:  254 KCGDLDVIFEYRAVTQKLTVTIVRAQGL-------------PDKDRSGVNSWQVHIVLLPSKKQRGKTNIQRGPNPVFKEKVTFTKLEPRDVASCAVRFRLYAARKMTRERMMGEKLFCLSHLHPEGEMKVTLVLEPRS-NLSSGE-SPLSPSVVSHSDSASSTQS-------LSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAANRAPDTYGKLFLLNCVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISIY 500
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BLAST of synaptotagmin-14 isoform X1 vs. UniProt/SwissProt
Match: sp|Q7TN84|SYT14_MOUSE (Synaptotagmin-14 OS=Mus musculus OX=10090 GN=Syt14 PE=2 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 1.500e-40
Identity = 119/407 (29.24%), Postives = 192/407 (47.17%), Query Frame = 1 
Query:  493 QDDLQPEHQS-ENSYHGETQGDESHSWNPKSEQFNNDENEDAQTLDDNTYS--------PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            QDD    H S   S  G+ + + SH  N     FN   +E +   +  +Y         P+D    +S  +++   S S++ +        K G + +    DSE+  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P   P+  ++ +  +   C   TS   +      L+ GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT   +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW  +  SK G+++ RWH  
Sbjct:  169 QDDSGSPHLSCTPSEIGDAKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSERQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNPSGCDSQVSLSEASCGDSTSSCQS------LQHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNRRSMKRKEMIGWISLGLNSSGEEELRHWTAMKESK-GQQVCRWHAL 552
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. UniProt/SwissProt
Match: sp|Q8NB59|SYT14_HUMAN (Synaptotagmin-14 OS=Homo sapiens OX=9606 GN=SYT14 PE=1 SV=2)

HSP 1 Score: 154.836 bits (390), Expect = 6.412e-39
Identity = 104/348 (29.89%), Postives = 173/348 (49.71%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  ++ +  +   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  228 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCDSQMSVSEMSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 552
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. UniProt/SwissProt
Match: sp|Q17RD7|SYT16_HUMAN (Synaptotagmin-16 OS=Homo sapiens OX=9606 GN=SYT16 PE=1 SV=2)

HSP 1 Score: 145.206 bits (365), Expect = 2.923e-35
Identity = 109/361 (30.19%), Postives = 175/361 (48.48%), Query Frame = 1 
Query:  589 FNNDENEDAQTLDDNT-YSPTDDFDNISEHELNLAVSGSKIERI-KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            FN+   ED+   D ++ +SP +      +   NL V     E I KCGD+ +     +    L +T++ A                P  +   V ++ +HV+++  KKHR +T +++GP+P F E +   K+   +     +RFRLY + +    +++GE    L  +  + +M+  ++L  +   I+         A     DS +S  S       L  G  PEL VGL++N  TGRL+V + +G++   L  N+ PDT+ KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L I  Y     K+K M G  +LG     EE + HW+++  +K G++I RWHT 
Sbjct:  311 FNSRGFEDSYATDSSSMWSPEE------QDRTNLQVPSGVSEPISKCGDLDVIFEYRAASQKLTVTIVRAQGL-------------PDKDRSGVNSWQVHVVLLPGKKHRGRTNIQRGPNPVFREKVTFAKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFYLSHLHPEGEMKVTLVLEPRS-NISSGGSPLSPSAV-SHSDSTSSTQS-------LSHGGAPELLVGLSYNATTGRLSVEMIKGSHFRNLAVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEEQDHWEEMKETK-GQQICRWHTL 642
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. UniProt/SwissProt
Match: sp|Q7TN83|SYT16_MOUSE (Synaptotagmin-16 OS=Mus musculus OX=10090 GN=Syt16 PE=1 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 4.086e-29
Identity = 79/269 (29.37%), Postives = 133/269 (49.44%), Query Frame = 1 
Query:  718 KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGY 1518
            KCGD+ +     +    L +T++ A                P  +   V ++ +H++++  KK R KT +++GP+P F E +  TK+   +     +RFRLY + +    +++GE    L  +  + +M+  ++L  +   ++  E + L  +     DS +S  S       L  G +PEL VGL++N  TGRL+V + +G++   L  N+ PDT+ KL L    G+E +  KT + +   NP + E F FQV  FQL D  L I  Y
Sbjct:  344 KCGDLDVIFEYRAVTQKLTVTIVRAQGL-------------PDKDRSGVNSWQVHIVLLPSKKQRGKTNIQRGPNPVFKEKVTFTKLEPRDVASCAVRFRLYAARKMTRERMMGEKLFCLSHLHPEGEMKVTLVLEPRS-NLSSGE-SPLSPSVVSHSDSASSTQS-------LSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAANRAPDTYGKLFLLNCVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISIY 590
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BLAST of synaptotagmin-14 isoform X1 vs. UniProt/SwissProt
Match: sp|Q58G82|SY14L_HUMAN (Putative synaptotagmin-14-like protein OS=Homo sapiens OX=9606 GN=SYT14P1 PE=5 SV=2)

HSP 1 Score: 80.1073 bits (196), Expect = 5.946e-16
Identity = 52/180 (28.89%), Postives = 89/180 (49.44%), Query Frame = 1 
Query: 1141 IAPNEMNTLIKATYCKCDS---ITSLVSTEKNSLF--LESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETAKTPVI--KASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            +  N +   I    C CDS   ++ +  +E  S    LE GS+PE+ + L +N   GRL+  + +G++L     N+ P+T++KL L  S  +E +K  +   +   NP + E F F+V  FQL    L +  Y     ++K +   +   +  GEE   +HW ++  SK G +++RW   
Sbjct:    8 LVQNTVQGTIHKIKCVCDSQMSVSEMSCSESTSACQSLEDGSVPEILISLLYNATNGRLSAEVIKGSHLKNWAANRPPNTYVKLTLRKSTDQEMSKCKISIRRGRPNPVYKETFVFKVTLFQLSHVTLMLSVYNKSSMRRKMIGWIYLGLNSSGEE--LNHWTEMKESK-GRQVRRWQAL 184
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. TrEMBL
Match: A0A484GQ10 (C2 domain-containing protein (Fragment) OS=Sousa chinensis OX=103600 GN=DBR06_SOUSAS5310012 PE=4 SV=1)

HSP 1 Score: 159.073 bits (401), Expect = 6.234e-38
Identity = 106/348 (30.46%), Postives = 174/348 (50.00%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  N+ + A+   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  208 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGIHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCNSQMSASEVSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 532
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. TrEMBL
Match: A0A2U4A017 (synaptotagmin-14 isoform X1 OS=Tursiops truncatus OX=9739 GN=SYT14 PE=4 SV=1)

HSP 1 Score: 158.688 bits (400), Expect = 1.099e-37
Identity = 106/348 (30.46%), Postives = 174/348 (50.00%), Query Frame = 1 
Query:  643 PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  N+ + A+   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  228 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGIHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCNSQMSASEVSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 552
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. TrEMBL
Match: A0A1L1SVE7 (Synaptotagmin-14 OS=Mus musculus OX=10090 GN=Syt14 PE=4 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 2.491e-37
Identity = 120/407 (29.48%), Postives = 194/407 (47.67%), Query Frame = 1 
Query:  493 QDDLQPEHQS-ENSYHGETQGDESHSWNPKSEQFNNDENE-----DAQTLDDNTYS---PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            QDD    H S   S  G+ + + SH  N     FN   +E     +A++  +  Y    P+D    +S  +++   S S++ +        K G + +    DSE+  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P   P+  ++ +  +   C   TS   +      L+ GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT   +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW  +  SK G+++ RWH  
Sbjct:  452 QDDSGSPHLSCTPSEIGDAKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSERQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNPSGCDSQVSLSEASCGDSTSSCQS------LQHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNRRSMKRKEMIGWISLGLNSSGEEELRHWTAMKESK-GQQVCRWHAL 835
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. TrEMBL
Match: F7GST4 (Synaptotagmin 14 OS=Callithrix jacchus OX=9483 GN=SYT14 PE=4 SV=3)

HSP 1 Score: 155.992 bits (393), Expect = 3.948e-37
Identity = 117/407 (28.75%), Postives = 195/407 (47.91%), Query Frame = 1 
Query:  493 QDDLQPEHQS-ENSYHGETQGDESHSWNPKSEQFNNDENEDAQTLDDNTYS--------PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            QDD    H S   S  G+++ + SH  N     +N   +E +   +  +Y         P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  ++ +  +   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT + +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  114 QDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESYHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCDSQMSVSEMSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 497
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. TrEMBL
Match: A0A2K5D3Y8 (Synaptotagmin 14 OS=Aotus nancymaae OX=37293 GN=SYT14 PE=4 SV=1)

HSP 1 Score: 156.377 bits (394), Expect = 7.532e-37
Identity = 118/407 (28.99%), Postives = 195/407 (47.91%), Query Frame = 1 
Query:  493 QDDLQPEHQS-ENSYHGETQGDESHSWNPKSEQFNNDENEDAQTLDDNTYS--------PTDDFDNISEHELNLAVSGSKIER-------IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            QDD    H S   S  G+++ + SH  N     +N   +E +   +  +Y         P+D    +S  +++   S S++ +        K G + +    DS++  L++TV    D              PT N     ++ +H++++ +KK R KT +++GP P F ET K   +  E    + +RFRLYG  R    +++GE    L K+++  KM   ++L   +P    +  ++ +  +   C   TS   +      LE GS+PE+ +GL +N  TGRL+  + +G++   L  N+ P+T++KL L  S G+E +  KT V +   NP + E F FQV  FQL D  L +  Y     K+K M G  SLG     EE  +HW ++  SK G+++ RWH  
Sbjct:  176 QDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESYHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI-------------PTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL---EPSYNHSGCDSQMSVSEMSCSESTSSCQS------LEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSVRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK-GQQVCRWHAL 559
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Cavefish
Match: syt14a (synaptotagmin-14 [Source:NCBI gene;Acc:103044022])

HSP 1 Score: 148.288 bits (373), Expect = 2.461e-37
Identity = 123/416 (29.57%), Postives = 190/416 (45.67%), Query Frame = 1 
Query:  475 QETSVDQDDLQPEHQSENSYHGETQGDESHSWNPKSEQFN------NDENEDAQTLDDNTYS---PTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDY----ARPSSSTLSIREHP----TGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDP--GIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            Q      +D  P      S  G+ + D SH  N     +            D ++  +  Y    P+D    +S    NL+  GS     K        G + E L    T+ +  DY     R + +  ++ + P    TGNV    ++ +H++++  KK R KT + +GP P F ET + + I  E    + +RFRLY   R    +++GE    L K+++  KM   ++L   DP   I  +E    I    C  D+ ++  S  +       GS PE+ +GL +N  TGRL+V + +G++   L  NK P+T++KL L  S G+E +  KT + +   NPT+ E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW  +  SK G+++ RWH+ 
Sbjct:  215 QPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSNSPLHSYTAKCPSEGSAGHDTESFLNKGYEEDVPSDSTAVLSPE--NLSARGSAAHLPK--------GYEPEPLAQFGTLDVVFDYDSCDQRLAVTVTAVTDIPPLKRTGNV----SWQVHLVLLPTKKQRAKTSIARGPCPIFTETFRFSHIESEMISNYAIRFRLYSVRRMKKEKILGEKVFYLTKLNLQGKMSVPVIL---DPCCSITGSESQASISDASCT-DTASTFQSAAQ-------GSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNTYVKLTLLNSMGQEMSKCKTSICRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTQMKESK-GQQVCRWHSL 604
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Cavefish
Match: syt14a (synaptotagmin-14 [Source:NCBI gene;Acc:103044022])

HSP 1 Score: 138.272 bits (347), Expect = 3.458e-34
Identity = 126/433 (29.10%), Postives = 189/433 (43.65%), Query Frame = 1 
Query:  475 QETSVDQDDLQPEHQSENSYHGETQGDESHSWNPKSEQFN------NDENEDAQTLDDNTYS---PTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDY----ARPSSSTLSIREHP----TGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVS------TEKNSLFLES--GSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPD-----------TFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            Q      +D  P      S  G+ + D SH  N     +            D ++  +  Y    P+D    +S    NL+  GS     K        G + E L    T+ +  DY     R + +  ++ + P    TGNV    ++ +H++++  KK R KT + +GP P F ET + + I  E    + +RFRLY   R    +++GE    L K+++  KM   ++L   DP                 C SITS  S      T+  S F  +  GS PE+ +GL +N  TGRL+V + +G++   L  NK P            T++KL L  S G+E +  KT + +   NPT+ E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW  +  SK G+++ RWH+ 
Sbjct:  156 QPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSNSPLHSYTAKCPSEGSAGHDTESFLNKGYEEDVPSDSTAVLSPE--NLSARGSAAHLPK--------GYEPEPLAQFGTLDVVFDYDSCDQRLAVTVTAVTDIPPLKRTGNV----SWQVHLVLLPTKKQRAKTSIARGPCPIFTETFRFSHIESEMISNYAIRFRLYSVRRMKKEKILGEKVFYLTKLNLQGKMSVPVIL---DP-----------------CCSITSQASISDASCTDTASTFQSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPSKYFHNFTTDSYTYVKLTLLNSMGQEMSKCKTSICRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTQMKESK-GQQVCRWHSL 553
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Cavefish
Match: syt14b (synaptotagmin-14-like [Source:NCBI gene;Acc:103040669])

HSP 1 Score: 135.191 bits (339), Expect = 1.036e-32
Identity = 102/351 (29.06%), Postives = 168/351 (47.86%), Query Frame = 1 
Query:  652 DFDNISEHELNLAVSGSKIERI----------KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESG--SMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXX-XXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            D D  SE    L    S + R+          K G + +    DS    L +TV  A D   P+  T       TGN+    ++ +H++++  KK R KT +++GP P F ET + + + Q+  +++ +RFRLY        +V+GE    L K+++  K     L +T +PG A              C S+ S+  +     +  +G  S PEL +GL +N +TGRL   + +G++      ++ P+T++KL++  SKG+E +  KT V +   NPT+ E F FQV  FQL +  L +  Y      ++       SLG     EE+E HW  +  ++ G ++ +WHT 
Sbjct:  391 DEDAPSESTAVLGPEDSSVARVPDFYEPEVLGKYGTLDVAFEYDSSTQHLAVTVTAATDI--PALKT-------TGNI----SWQVHLVLLPTKKQRAKTGVQKGPCPVFTETFRFSPVEQDALREYAVRFRLYSVRHRKKEKVLGEKVFYLTKLNLQGKT---ALPVTLEPGSA-----------VPGCGSLVSVSRSVGALSYHSTGESSTPELLLGLLYNSSTGRLAAEVIKGSHFKNSATDQPPNTYVKLVMLDSKGKEMSKCKTSVCRGQPNPTYKETFMFQVALFQLSEVTLQVMVYSRRSSMRRRERVGWVSLGLNSTTEEQEEHWAQMKEAE-GRQVCQWHTL 713
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Cavefish
Match: syt16 (synaptotagmin XVI [Source:ZFIN;Acc:ZDB-GENE-090313-210])

HSP 1 Score: 124.02 bits (310), Expect = 1.689e-29
Identity = 99/327 (30.28%), Postives = 155/327 (47.40%), Query Frame = 1 
Query:  715 IKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDK-KMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPD---------TFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            +KCGD+ I +    E   L++TV+ A      + S +              ++ +HV ++  K+ RYKT +++G  P F ET + +++ Q E     LRFRLY   +    +++GE    L K++ +  +M+  ++L          E  + +KA   +        S   +      G +PEL +GLA+N  TGRL+V I +G++   L  N+ P          T+ KL L  S G+E +  KT V +   NP F E F FQV  FQL D  L +  Y     K+K M G  +LG     EE   HW+D+  S   +++ RWHT 
Sbjct:  233 LKCGDLIIVLDYRPETFKLLVTVVTAQGIPDKARSGMD-------------SWQVHVALLPGKRQRYKTAVQRGSAPRFGETFRFSRLEQAELGSSALRFRLYALGKMNRERMMGETIYRLSKLNTESGQMEATLVL----------EPRSNLKAIDSQVSLSAQSDSASSSQSLSH-GGVPELLLGLAYNATTGRLSVEIIKGSHFRNLALNRPPGNNNYNNNNNTYGKLTLLNSMGQEISRCKTSVRRGQPNPVFKETFVFQVALFQLSDVTLMVAVYNRRNMKRKEMIGWLALGQNSSGEEEALHWQDMKESGN-QQVCRWHTL 534
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Cavefish
Match: syt14b (synaptotagmin-14-like [Source:NCBI gene;Acc:103040669])

HSP 1 Score: 125.176 bits (313), Expect = 2.130e-29
Identity = 103/370 (27.84%), Postives = 168/370 (45.41%), Query Frame = 1 
Query:  652 DFDNISEHELNLAVSGSKIERI----------KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESG--SMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLP-------------------DTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXX-XXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            D D  SE    L    S + R+          K G + +    DS    L +TV  A D   P+  T       TGN+    ++ +H++++  KK R KT +++GP P F ET + + + Q+  +++ +RFRLY        +V+GE    L K+++  K     L +T +PG A              C S+ S+  +     +  +G  S PEL +GL +N +TGRL   + +G++      ++ P                   DT++KL++  SKG+E +  KT V +   NPT+ E F FQV  FQL +  L +  Y      ++       SLG     EE+E HW  +  ++ G ++ +WHT 
Sbjct:  391 DEDAPSESTAVLGPEDSSVARVPDFYEPEVLGKYGTLDVAFEYDSSTQHLAVTVTAATDI--PALKT-------TGNI----SWQVHLVLLPTKKQRAKTGVQKGPCPVFTETFRFSPVEQDALREYAVRFRLYSVRHRKKEKVLGEKVFYLTKLNLQGKT---ALPVTLEPGSA-----------VPGCGSLVSVSRSVGALSYHSTGESSTPELLLGLLYNSSTGRLAAEVIKGSHFKNSATDQPPSGLFCCIKRFIGGQLYIMRDTYVKLVMLDSKGKEMSKCKTSVCRGQPNPTYKETFMFQVALFQLSEVTLQVMVYSRRSSMRRRERVGWVSLGLNSTTEEQEEHWAQMKEAE-GRQVCQWHTL 732
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005109.1 (pep scaffold:Pmarinus_7.0:GL487076:302:1441:-1 gene:ENSPMAG00000004645.1 transcript:ENSPMAT00000005109.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.003 bits (149), Expect = 1.472e-11
Identity = 38/137 (27.74%), Postives = 65/137 (47.45%), Query Frame = 1 
Query:  688 AVSGSKIERI-KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDID 1095
            AV+  + E I KCG++ +K+   +    L +TVL AHD              P         + +H++++  K+ R+KT ++ G  P F E+ + + +   E   + LRFRLY        +++GE  L L K+  D
Sbjct:   24 AVAAKQNEPISKCGNLDVKVAYSTGAQKLEVTVLSAHDI-------------PAKQRSGANTWQVHLVLLPTKRQRFKTSVQNGETPVFQESFRFSALEPGELSTYALRFRLYAVRSMNRERMMGEKLLYLSKLSPD 147
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Nematostella
Match: EDO41224 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4W3])

HSP 1 Score: 119.783 bits (299), Expect = 6.062e-30
Identity = 89/311 (28.62%), Postives = 158/311 (50.80%), Query Frame = 1 
Query:  748 LDSEKLTLIMTVLLAHDYARPSSSTLSI-----REHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEET--AKTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            +  E L+    + ++  YA P++  LS+      + PT       +  + ++++  KK R+KTK +   +P F+ET   T+I Q E +  CLR RLYG  R    +++GE  + L + ++D   +   L  T  PG A    +++   +            +  +   ++SG+ PEL V L +   TGRLTV + + +NL  +   + PDT++K+ +  S G++   +KT + ++  +P F+E F FQ+  F+L    L      + K ++K + G FS+G     E+ E HWK+++  K G+ +KRWH  
Sbjct:    1 MRDEVLSTAGRIQISASYA-PTAEKLSVTVVRAEDIPTKQRGGASSVQVRIVILPTKKQRFKTKAKPATNPNFHETFTFTRITQNELRNLCLRVRLYGHERIGKDKLLGESKIELTEFELDG--EGTPLWRTLTPGNAIGSSDSMYDLSDTGSVHSFGSYGSSSSLAMVQSGA-PELLVSLCYQSLTGRLTVEVLKASNLRNVAMQRAPDTYVKVSMFNSIGQQLSKSKTSIRRSMYDPEFNETFVFQIIEFELPSVSLMFSVVNIKKMRRKEIMGWFSMGRDNTGEDEESHWKEMIEGK-GKAVKRWHVL 306
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Nematostella
Match: EDO47875 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL62])

HSP 1 Score: 66.6254 bits (161), Expect = 3.689e-12
Identity = 70/274 (25.55%), Postives = 125/274 (45.62%), Query Frame = 1 
Query:  877 IHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTF--IKLILS----ISKGEETAKTPVIKASNNPTFDEIFSFQVCGFQLDD-SILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTFDMHT*P 1677
            + V+++  K+  ++ K ++     FN+ + I    +++ K   LRFRLY         ++GEG L L  V++D +M   + +  Q PG            +Y    +  +++   +  L +     PE+ + L +   TG+L + + +  NL  L D+K  + +  +KLI S    ISKG  T +  +I    +P ++E+F F V   +L+  ++L           +K   G  +LG     EE   HW ++  SK  + I RWH  +  T P
Sbjct:   28 VSVMLLPGKRQSFRAKPKE-----FNDPVAIYLYPKDKVKDMSLRFRLYEHGSMGARHLLGEGVLRLRNVNLDNEM-VPVAVDLQPPG------------SYVPEGASGAIMY--EGELAISEEDRPEILISLEYRRLTGKLLLEVIKTRNLGMLTDSKAKEMYVSVKLIGSNGELISKGRTTPRRHMI----DPEYNEMFLFHVPEQELNSVTVLIALTSVSKTLGRKLKVGQLALGQNYSSEEEYRHWFEMTRSKE-KSIVRWHRINEMTVP 276
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Medaka
Match: syt14a (synaptotagmin 14 [Source:NCBI gene;Acc:101155984])

HSP 1 Score: 142.895 bits (359), Expect = 8.446e-36
Identity = 101/318 (31.76%), Postives = 157/318 (49.37%), Query Frame = 1 
Query:  718 KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLF--LESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            K G + I    DSE+  L +T++             ++ + PT    A +++ +H++++  KK R KT +++GP P F ET + + +  E    + +RFRLY   R    +V GE    L K+++  KM   ++L   DP        + +        S++ +  +E  S F  +   S PE+ VGL +N  TGRL+V I +G +   L  NK P+T++KL L  S G E +  KT + +   NPT+ E F FQV  FQL D  L +  Y     K+K M G  SLG     EE   HW  +  SK G+++  WH+ 
Sbjct:  246 KFGTLDIVFDYDSEEQQLAVTIM-------------AVTDLPTVKRTANISWQVHLVLLPTKKQRAKTGVQRGPCPIFTETFRFSHVESEMISNYAIRFRLYSMRRMKKEKVFGEKVFYLTKLNLQGKMSVPVIL---DPCCPIPGGESQV--------SLSDMTCSESASSFQSVSQASTPEILVGLVYNATTGRLSVEIIKGIHFKNLAANKPPNTYVKLTLLNSMGHEMSKCKTSICRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTQMKESK-GQQVCHWHSL 538
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Medaka
Match: ENSORLT00000022607.2 (synaptotagmin 16 [Source:NCBI gene;Acc:101173827])

HSP 1 Score: 128.257 bits (321), Expect = 7.299e-31
Identity = 104/362 (28.73%), Postives = 172/362 (47.51%), Query Frame = 1 
Query:  592 NNDENEDAQTLDDNTYSPTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYG----SFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            + D+NE A +   +T+SP  +    S     L  S S+    KCGD+ + +        L+++VL             S R  P  +   + ++ +H+L++  KK R+KT +++GP P FNET++ + +   +     +RFRLY      FR  M   +GE  L L  +D         +++  +P      + + +  +      I S   +      L  G +PEL +GL++N  TGR++V + RG+    L  ++ PDT+ +L L  S G+E A  KT V +   NP + E F FQV  FQL D  L +        K+K M G  +LG     +E + HW+ +  S+ G+++ RWH  
Sbjct:  222 DQDKNEAADS--SSTWSPEQERTLHSSASSQLLCSSSRPPICKCGDLVLSLEYRPSLRKLLVSVL-------------SARGVPDKDRSGLDSWQVHMLLLPTKKQRHKTSVQKGPCPHFNETLRFSHVEPTDLHTSAVRFRLYALGGRMFRERM---VGEKVLCLGGLDPQGGTTETTVVL--EPRSNLKHVGSQLSLSAASQSDIASFTQS------LTHGGVPELLLGLSYNATTGRMSVELIRGSLFRNLAVSRPPDTYGRLTLLNSVGQEIARCKTSVRRGQPNPVYKETFVFQVALFQLSDVTLLVSINTRRSMKRKEMVGWIALGQNSSGKEEQLHWQVMKESR-GQQVCRWHVL 556
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Medaka
Match: syt14b (synaptotagmin-14 [Source:NCBI gene;Acc:101173829])

HSP 1 Score: 117.087 bits (292), Expect = 7.694e-27
Identity = 97/338 (28.70%), Postives = 161/338 (47.63%), Query Frame = 1 
Query:  718 KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLES--GSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNK-------------------LPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGY-QXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            K G + +    DS +  L +TV  A D         ++++  TGN+    ++ +H++++  KK R KT +++GP P F ET K +++ QE      +RFRLY   R    +V+GE    L K+++  K+    L +T +PG           +    C S+ S VS    +L   S   S+PE+ +GL +N  TGRL+  + +G +      +K                   + DT++KL +  SKG+E +  KT   +   NPT+ E F FQV  FQL +  L +  + +    + +   G  SLG     EE+  HW ++  ++ G++I  WHT 
Sbjct:  423 KYGTLDVAFEYDSSEQWLAVTVTAATDIP-------ALKQ--TGNI----SWQVHLVLLPTKKQRAKTGVQKGPCPVFTETFKFSRVEQEALGDCAVRFRLYSIRRMKKEKVLGEKVFYLTKLNLQGKI---ALPVTLEPG-----------SELPGCGSLVS-VSRSAGALSYRSTEDSLPEILLGLIYNSATGRLSAEVIQGNHFKTAASDKPISDLFCCVKHFVGGQLYIMRDTYVKLTMLDSKGKEMSKCKTATCRGHPNPTYKETFVFQVALFQLSEVSLVVSVFCRRSSMRPRERLGWVSLGLNSTSEEQLVHWTEMREAE-GQQICHWHTL 731
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Medaka
Match: syt14b (synaptotagmin-14 [Source:NCBI gene;Acc:101173829])

HSP 1 Score: 114.775 bits (286), Expect = 1.565e-26
Identity = 95/336 (28.27%), Postives = 160/336 (47.62%), Query Frame = 1 
Query:  718 KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNK-------------------LPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGY-QXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            K G + +    DS +  L +TV  A D         ++++  TGN+    ++ +H++++  KK R KT +++GP P F ET K +++ QE      +RFRLY   R    +V+GE    L K+++  K+    L +T +PG       +L+  +  +     S  STE         S+PE+ +GL +N  TGRL+  + +G +      +K                   + DT++KL +  SKG+E +  KT   +   NPT+ E F FQV  FQL +  L +  + +    + +   G  SLG     EE+  HW ++  ++ G++I  WHT 
Sbjct:  211 KYGTLDVAFEYDSSEQWLAVTVTAATDIP-------ALKQ--TGNI----SWQVHLVLLPTKKQRAKTGVQKGPCPVFTETFKFSRVEQEALGDCAVRFRLYSIRRMKKEKVLGEKVFYLTKLNLQGKIA---LPVTLEPGSELPGCGSLVSVS--RSAGALSYRSTED--------SLPEILLGLIYNSATGRLSAEVIQGNHFKTAASDKPISDLFCCVKHFVGGQLYIMRDTYVKLTMLDSKGKEMSKCKTATCRGHPNPTYKETFVFQVALFQLSEVSLVVSVFCRRSSMRPRERLGWVSLGLNSTSEEQLVHWTEMREAE-GQQICHWHTL 519
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Medaka
Match: ENSORLT00000031837.1 (double C2-like domain-containing protein alpha [Source:NCBI gene;Acc:101175439])

HSP 1 Score: 71.2478 bits (173), Expect = 9.657e-13
Identity = 71/267 (26.59%), Postives = 119/267 (44.57%), Query Frame = 1 
Query:  877 IHVLVVQVKKHRYKTKM-RQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAF----NCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA-KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTF 1659
            +H+L    K ++ KTK+ R   +P +NET+    I +E+  +  LR  +    +    + IGE  + L +V  D+    +I L    P  +P  MNT ++   C          TE+     E G    L + L F        G L V ++R  +L  +  N   D ++K  L     +++  KT VIK + NP F+E F +++   +L    L +  +     +     G  SLG    + +   HW D L +K G++++RWHT 
Sbjct:  119 LHLLPGACKANKLKTKIVRNTLNPVWNETLTYCGITEEDMYRKTLRVSVCDEDKLTHNEFIGESRVALRRVKPDQTKHFNICLEHPPPLPSPTAMNTALRGISCYLKEW----ETEQQRSLEERG---RLLLCLQFLPPNKSARGGLCVGVKRCAHLAAMDVNGFSDPYVKTYLKPDVQKKSKHKTAVIKKTLNPEFNEEFFYEISFSELATKTLEVTVWDYDLGRSNDFIGGVSLGCH-SQGDALQHWIDCLKNK-GKKVERWHTL 376
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Planmine SMEST
Match: SMESG000070077.1 (SMESG000070077.1)

HSP 1 Score: 941.414 bits (2432), Expect = 0.000e+0
Identity = 475/478 (99.37%), Postives = 475/478 (99.37%), Query Frame = 1 
Query:  238 MALLGKSLQSTHSHSGFKSVFNIRTVFFCCSKSETEPRNDEEIAENNKQIKKEDLEEVTEKTIEPKLDTSNDPVEVKTAQETSVDQDDLQPEHQSENSYHGETQGDESHSWNPKSEQFNNDENEDAQTLDDNTYSPTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETAKTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTFDMHT 1671
            MALLGKSLQSTHSHSGFKSVFNIRTVFFCCSKSETEPRNDEEIA NN QIKKEDLEEVTEKTIEPKLDTSNDPVEVKTAQETSVDQDDLQPEHQSENSY GETQGDESHSWNPKSEQFNNDENEDAQTLDDNTYSPTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETAKTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQMLKFKKKFMFGSFSLGSKVGEEEREHHWKDLLLSKTGEEIKRWHTFDMHT
Sbjct:    1 MALLGKSLQSTHSHSGFKSVFNIRTVFFCCSKSETEPRNDEEIAVNNNQIKKEDLEEVTEKTIEPKLDTSNDPVEVKTAQETSVDQDDLQPEHQSENSYRGETQGDESHSWNPKSEQFNNDENEDAQTLDDNTYSPTDDFDNISEHELNLAVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETAKTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQMLKFKKKFMFGSFSLGSKVGEEEREHHWKDLLLSKTGEEIKRWHTFDMHT 478
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Planmine SMEST
Match: SMESG000051011.1 (SMESG000051011.1)

HSP 1 Score: 131.339 bits (329), Expect = 2.481e-32
Identity = 107/330 (32.42%), Postives = 164/330 (49.70%), Query Frame = 1 
Query:  694 SGSKIERI-KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITS--LVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTFDMH 1668
            SGS I +  K   VR+ + LDS    L + +L   D     +   + + +      +V +Y IH  V+ VKK R+K+K+RQG DP FNE   + KIN+E      LRFRLYGS + +   +IG+    L  +D+    + +  L   +PG         I  T  +  S+ S  +   ++N         PEL +GL+ N N+GRLTV I RG++L K K+    D ++KL L  S G+E +  KT + K + +P F E F FQV  FQ+ +  L I         +K + G  +LG K   EE  +HW +++    G + +  H+  +H
Sbjct:  152 SGSIIRKGNKMAIVRVHLFLDSLSSKLKIQILQVFDLFGTENRIDTKKTNVLSRTSSVYSYQIHCSVLPVKKFRFKSKIRQGADPMFNEVFYVPKINEEAANSITLRFRLYGS-QTSTLNMIGQCLCDLSSIDLSVDTEYN--LTISEPGEDDVISTDQISVTGSEIRSVISENIEGHDRN---------PELMIGLSHNSNSGRLTVEIIRGSSLSKEKN---KDFYVKLSLFSSNGQELSHTKTSIRKNTISPVFKESFMFQVALFQMKEVTLMISVVAKKSIHRKEVVGWVALGYKSSGEEELNHWSEIM---EGAKSEVMHSHRLH 463
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Planmine SMEST
Match: SMESG000051011.1 (SMESG000051011.1)

HSP 1 Score: 129.798 bits (325), Expect = 3.431e-32
Identity = 107/330 (32.42%), Postives = 164/330 (49.70%), Query Frame = 1 
Query:  694 SGSKIERI-KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITS--LVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTFDMH 1668
            SGS I +  K   VR+ + LDS    L + +L   D     +   + + +      +V +Y IH  V+ VKK R+K+K+RQG DP FNE   + KIN+E      LRFRLYGS + +   +IG+    L  +D+    + +  L   +PG         I  T  +  S+ S  +   ++N         PEL +GL+ N N+GRLTV I RG++L K K+    D ++KL L  S G+E +  KT + K + +P F E F FQV  FQ+ +  L I         +K + G  +LG K   EE  +HW +++    G + +  H+  +H
Sbjct:  106 SGSIIRKGNKMAIVRVHLFLDSLSSKLKIQILQVFDLFGTENRIDTKKTNVLSRTSSVYSYQIHCSVLPVKKFRFKSKIRQGADPMFNEVFYVPKINEEAANSITLRFRLYGS-QTSTLNMIGQCLCDLSSIDLSVDTEYN--LTISEPGEDDVISTDQISVTGSEIRSVISENIEGHDRN---------PELMIGLSHNSNSGRLTVEIIRGSSLSKEKN---KDFYVKLSLFSSNGQELSHTKTSIRKNTISPVFKESFMFQVALFQMKEVTLMISVVAKKSIHRKEVVGWVALGYKSSGEEELNHWSEIM---EGAKSEVMHSHRLH 417
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Planmine SMEST
Match: SMESG000051011.1 (SMESG000051011.1)

HSP 1 Score: 127.872 bits (320), Expect = 2.622e-31
Identity = 107/330 (32.42%), Postives = 164/330 (49.70%), Query Frame = 1 
Query:  694 SGSKIERI-KCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIREHPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITS--LVSTEKNSLFLESGSMPELFVGLAFNCNTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETA--KTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTFDMH 1668
            SGS I +  K   VR+ + LDS    L + +L   D     +   + + +      +V +Y IH  V+ VKK R+K+K+RQG DP FNE   + KIN+E      LRFRLYGS + +   +IG+    L  +D+    + +  L   +PG         I  T  +  S+ S  +   ++N         PEL +GL+ N N+GRLTV I RG++L K K+    D ++KL L  S G+E +  KT + K + +P F E F FQV  FQ+ +  L I         +K + G  +LG K   EE  +HW +++    G + +  H+  +H
Sbjct:  137 SGSIIRKGNKMAIVRVHLFLDSLSSKLKIQILQVFDLFGTENRIDTKKTNVLSRTSSVYSYQIHCSVLPVKKFRFKSKIRQGADPMFNEVFYVPKINEEAANSITLRFRLYGS-QTSTLNMIGQCLCDLSSIDLSVDTEYN--LTISEPGEDDVISTDQISVTGSEIRSVISENIEGHDRN---------PELMIGLSHNSNSGRLTVEIIRGSSLSKEKNK---DFYVKLSLFSSNGQELSHTKTSIRKNTISPVFKESFMFQVALFQMKEVTLMISVVAKKSIHRKEVVGWVALGYKSSGEEELNHWSEIM---EGAKSEVMHSHRLH 448
[Close]
BLAST of synaptotagmin-14 isoform X1 vs. Planmine SMEST
Match: SMESG000024484.1 (SMESG000024484.1)

HSP 1 Score: 84.7297 bits (208), Expect = 5.102e-17
Identity = 86/302 (28.48%), Postives = 142/302 (47.02%), Query Frame = 1 
Query:  817 STLSIREHPTGNVPAVL--AYSIHVLVVQV------KKHRYKTKMRQGPDPFFNETIKITKINQEETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDPGIAPNEMNTLIKATYCKCDSITSLVS--TEKNSLFLES--GSMPELFVGLAFNCNTGRLTVFIRRGT---NLPKLKDNKLPDTFIKLILSISKGEET--AKTPVIKASNNPTFDEIFSFQVCGFQLDDSILTIQGYQXXXXXXXXXXXXXXXXXXVGEEEREHHWKDLLLSKTGEEIKRWHTFDMHT 1671
            S L+I  H   ++P+ L    S ++L V +      K  R+ +K          ET++  +++ ++     +R RLYG  R     ++ E  + L  VD+ K+ Q  + +  +       E+  L K      D   +     ++K ++ +E   G   E+ +GLA+N  TGRLTV I +G    N     D+KLP++F+K+ LS    +E   +KT + +   NP F E F FQV  FQL++  +    Y      +K + G FS+G      E   HWK++  S  GEE+ +WH    +T
Sbjct:  154 SLLAITFHGVDHLPSKLVGGTSAYLLAVAIFDESDKKLFRWNSKQFASNSFRIPETMEFPEMSAKDISTTAVRIRLYGCERKRRDILLSETIIGLGNVDLKKQEQYRLKMEKRA------ELKHLDKKNIEMGDDENNFAKEMSKKATIQVEETIGVEAEMLLGLAYNPITGRLTVEIVKGNAFKNPLSRNDDKLPNSFVKVTLSAENNQEITRSKTELRRNQANPLFKEKFMFQVPQFQLNEITIIFGVYHRKSAHRKEIIGWFSIGLNNSSPEELSHWKNMQQS-NGEEVFQWHELLQNT 448
The following BLAST results are available for this feature:
BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SYT145.934e-4029.89synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:2314... [more]
SYT145.934e-4029.89synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:2314... [more]
SYT141.335e-3929.89synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:2314... [more]
SYT144.783e-3627.70synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:2314... [more]
SYT145.651e-3627.70synaptotagmin 14 [Source:HGNC Symbol;Acc:HGNC:2314... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Syt145.496e-3233.21gene:FBgn0261086 transcript:FBtr0336485[more]
Syt145.496e-3233.21gene:FBgn0261086 transcript:FBtr0078957[more]
Syt147.492e-3233.21gene:FBgn0261086 transcript:FBtr0339551[more]
Syt48.228e-923.35gene:FBgn0028400 transcript:FBtr0081578[more]
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syt14a1.427e-3630.72synaptotagmin XIVa [Source:ZFIN;Acc:ZDB-GENE-09031... [more]
syt14a1.368e-3329.40synaptotagmin XIVa [Source:ZFIN;Acc:ZDB-GENE-09031... [more]
syt14b4.203e-3330.67synaptotagmin XIVb [Source:ZFIN;Acc:ZDB-GENE-04101... [more]
syt14a5.034e-3329.40synaptotagmin XIVa [Source:ZFIN;Acc:ZDB-GENE-09031... [more]
syt14a6.136e-3329.40synaptotagmin XIVa [Source:ZFIN;Acc:ZDB-GENE-09031... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SYT148.758e-3628.45synaptotagmin 14 [Source:NCBI gene;Acc:100491102][more]
SYT141.110e-3528.45synaptotagmin 14 [Source:NCBI gene;Acc:100491102][more]
SYT141.759e-3528.45synaptotagmin 14 [Source:NCBI gene;Acc:100491102][more]
SYT143.044e-3529.31synaptotagmin 14 [Source:NCBI gene;Acc:100491102][more]
tjp11.467e-1039.66tight junction protein 1 [Source:Xenbase;Acc:XB-GE... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Syt142.144e-4129.24synaptotagmin XIV [Source:MGI Symbol;Acc:MGI:24444... [more]
Syt141.201e-4029.48synaptotagmin XIV [Source:MGI Symbol;Acc:MGI:24444... [more]
Syt148.644e-3828.17synaptotagmin XIV [Source:MGI Symbol;Acc:MGI:24444... [more]
Syt165.841e-3029.37synaptotagmin XVI [Source:MGI Symbol;Acc:MGI:26738... [more]
Syt161.603e-2929.37synaptotagmin XVI [Source:MGI Symbol;Acc:MGI:26738... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7TN84|SYT14_MOUSE1.500e-4029.24Synaptotagmin-14 OS=Mus musculus OX=10090 GN=Syt14... [more]
sp|Q8NB59|SYT14_HUMAN6.412e-3929.89Synaptotagmin-14 OS=Homo sapiens OX=9606 GN=SYT14 ... [more]
sp|Q17RD7|SYT16_HUMAN2.923e-3530.19Synaptotagmin-16 OS=Homo sapiens OX=9606 GN=SYT16 ... [more]
sp|Q7TN83|SYT16_MOUSE4.086e-2929.37Synaptotagmin-16 OS=Mus musculus OX=10090 GN=Syt16... [more]
sp|Q58G82|SY14L_HUMAN5.946e-1628.89Putative synaptotagmin-14-like protein OS=Homo sap... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A484GQ106.234e-3830.46C2 domain-containing protein (Fragment) OS=Sousa c... [more]
A0A2U4A0171.099e-3730.46synaptotagmin-14 isoform X1 OS=Tursiops truncatus ... [more]
A0A1L1SVE72.491e-3729.48Synaptotagmin-14 OS=Mus musculus OX=10090 GN=Syt14... [more]
F7GST43.948e-3728.75Synaptotagmin 14 OS=Callithrix jacchus OX=9483 GN=... [more]
A0A2K5D3Y87.532e-3728.99Synaptotagmin 14 OS=Aotus nancymaae OX=37293 GN=SY... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syt14a2.461e-3729.57synaptotagmin-14 [Source:NCBI gene;Acc:103044022][more]
syt14a3.458e-3429.10synaptotagmin-14 [Source:NCBI gene;Acc:103044022][more]
syt14b1.036e-3229.06synaptotagmin-14-like [Source:NCBI gene;Acc:103040... [more]
syt161.689e-2930.28synaptotagmin XVI [Source:ZFIN;Acc:ZDB-GENE-090313... [more]
syt14b2.130e-2927.84synaptotagmin-14-like [Source:NCBI gene;Acc:103040... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000005109.11.472e-1127.74pep scaffold:Pmarinus_7.0:GL487076:302:1441:-1 gen... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO412246.062e-3028.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO478753.689e-1225.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syt14a8.446e-3631.76synaptotagmin 14 [Source:NCBI gene;Acc:101155984][more]
ENSORLT00000022607.27.299e-3128.73synaptotagmin 16 [Source:NCBI gene;Acc:101173827][more]
syt14b7.694e-2728.70synaptotagmin-14 [Source:NCBI gene;Acc:101173829][more]
syt14b1.565e-2628.27synaptotagmin-14 [Source:NCBI gene;Acc:101173829][more]
ENSORLT00000031837.19.657e-1326.59double C2-like domain-containing protein alpha [So... [more]
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BLAST of synaptotagmin-14 isoform X1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000070077.10.000e+099.37SMESG000070077.1[more]
SMESG000051011.12.481e-3232.42SMESG000051011.1[more]
SMESG000051011.13.431e-3232.42SMESG000051011.1[more]
SMESG000051011.12.622e-3132.42SMESG000051011.1[more]
SMESG000024484.15.102e-1728.48SMESG000024484.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033835 ID=SMED30033835|Name=synaptotagmin-14 isoform X1|organism=Schmidtea mediterranea sexual|type=transcript|length=1982bp
CCTCAAAAACTCGAAAAATATTAATAAAAAGCAATTTTCATTTCGGACCG
GAAAAATCAAAATTGAAAGTTGTAATTGTTTTTTCATGTTTTGTGTATTT
TTTAATTGAAATAAACGCTCGATCAATAATTGCCAATAAAATGTGCCCAT
GTGCCAATTGGTTGTGTGCCGGTGGGGAAACGCTCTCCTATTGGTTCGAT
TTGACATTGCAATTATCGACCAGTTCACAATTCCAGAATGGCTTTGCTCG
GGAAATCTTTGCAGTCAACACATTCTCACAGTGGATTTAAATCTGTTTTC
AATATTAGAACGGTTTTCTTTTGTTGCTCAAAATCGGAAACTGAGCCGAG
AAACGATGAGGAAATTGCCGAGAATAATAAACAAATCAAGAAGGAAGATT
TGGAAGAGGTTACAGAGAAAACGATTGAACCTAAACTTGACACATCGAAT
GATCCAGTCGAAGTAAAAACAGCACAAGAAACCTCTGTCGACCAGGACGA
TTTACAACCAGAACATCAAAGTGAGAATAGTTACCATGGCGAAACACAAG
GTGACGAGTCGCACTCATGGAATCCAAAATCTGAGCAATTTAATAATGAT
GAAAATGAAGATGCTCAAACATTGGATGACAATACTTATTCTCCTACGGA
TGACTTTGATAACATATCCGAGCACGAATTAAATTTAGCGGTATCTGGAT
CAAAAATTGAAAGAATAAAATGTGGAGATGTGCGAATAAAAATCGGATTA
GATTCCGAGAAACTCACTTTAATAATGACAGTTCTTCTTGCACATGATTA
TGCCAGACCCTCTTCAAGCACGTTATCGATCCGTGAACATCCAACAGGTA
ATGTTCCAGCTGTGTTAGCCTATTCAATCCACGTTTTGGTGGTACAAGTC
AAAAAGCATCGGTATAAGACAAAAATGAGACAAGGCCCTGATCCGTTTTT
TAATGAAACGATAAAGATAACTAAAATTAATCAAGAAGAAACAAAAAAGT
GGTGTTTAAGGTTTAGATTATATGGCAGTTTCCGTAATGCAATGACACAA
GTTATTGGTGAAGGTTTCTTGCCTTTGGAAAAGGTCGACATAGATAAAAA
AATGCAATGCGATATATTGTTGATGACACAGGATCCAGGAATAGCACCAA
ACGAAATGAATACGCTAATCAAGGCAACTTATTGCAAATGTGATTCAATA
ACTTCTTTAGTCAGTACAGAGAAAAACTCACTTTTCCTTGAAAGTGGATC
CATGCCAGAATTGTTTGTTGGACTTGCTTTCAATTGCAACACGGGAAGGC
TAACCGTATTTATTAGACGGGGAACAAATCTACCGAAGCTGAAGGATAAC
AAACTTCCTGATACTTTCATCAAACTAATTCTGTCTATAAGTAAAGGAGA
AGAAACGGCAAAAACGCCAGTTATAAAGGCGAGCAACAACCCGACTTTTG
ATGAAATTTTTAGTTTCCAAGTTTGCGGATTCCAGCTTGACGATTCCATT
CTTACAATTCAAGGCTATCAAATGCTTAAATTTAAGAAGAAATTCATGTT
CGGTTCTTTCAGTCTTGGGAGTAAAGTCGGAGAGGAAGAACGAGAACACC
ATTGGAAAGACCTTTTATTATCAAAAACCGGAGAAGAAATCAAACGCTGG
CACACCTTTGATATGCATACGTAACCATATCCGTTCTGCATAATTATTCC
TCTTCGAACTGAAATTGACCTAGAGTTGACGAGTTCTTTCTTAGATTTAT
TATTTACTGTGGAAAGGACTTTTAAAACCCTTCGAAACGATCTATAAAAT
TCAAGAACAAATATTCATCAGTTTAGGGCCCTTGAGATTAAAGCTACGTT
GTTGTAAATTAAAAGTGACATGTTCCGACTCACAACAATGAAGAAACTGC
ATAATTCCATCCAGCGATTAAAGAATCAAGTTGAATACGAGAAGTCCGGG
CTAAAAGCTCAAAGAATTCATACAAAGTCCTG
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protein sequence of SMED30033835-orf-1

>SMED30033835-orf-1 ID=SMED30033835-orf-1|Name=SMED30033835-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=479bp
MALLGKSLQSTHSHSGFKSVFNIRTVFFCCSKSETEPRNDEEIAENNKQI
KKEDLEEVTEKTIEPKLDTSNDPVEVKTAQETSVDQDDLQPEHQSENSYH
GETQGDESHSWNPKSEQFNNDENEDAQTLDDNTYSPTDDFDNISEHELNL
AVSGSKIERIKCGDVRIKIGLDSEKLTLIMTVLLAHDYARPSSSTLSIRE
HPTGNVPAVLAYSIHVLVVQVKKHRYKTKMRQGPDPFFNETIKITKINQE
ETKKWCLRFRLYGSFRNAMTQVIGEGFLPLEKVDIDKKMQCDILLMTQDP
GIAPNEMNTLIKATYCKCDSITSLVSTEKNSLFLESGSMPELFVGLAFNC
NTGRLTVFIRRGTNLPKLKDNKLPDTFIKLILSISKGEETAKTPVIKASN
NPTFDEIFSFQVCGFQLDDSILTIQGYQMLKFKKKFMFGSFSLGSKVGEE
EREHHWKDLLLSKTGEEIKRWHTFDMHT*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR035892C2_domain_sf
IPR000008C2_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0005509calcium ion binding
GO:0005543phospholipid binding
GO:0019905syntaxin binding
GO:0030276clathrin binding
GO:0042803protein homodimerization activity
GO:0046982protein heterodimerization activity
Vocabulary: cellular component
TermDefinition
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006906vesicle fusion
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000008C2 domainSMARTSM00239C2_3ccoord: 354..456
e-value: 2.8E-6
score: 36.9
coord: 177..292
e-value: 13.0
score: 6.9
IPR000008C2 domainPFAMPF00168C2coord: 216..287
e-value: 0.0018
score: 18.5
coord: 353..455
e-value: 2.9E-8
score: 33.9
IPR000008C2 domainPROSITEPS50004C2coord: 354..442
score: 10.012
IPR035892C2 domain superfamilyGENE3DG3DSA:2.60.40.150coord: 321..477
e-value: 8.9E-23
score: 82.5
IPR035892C2 domain superfamilyGENE3DG3DSA:2.60.40.150coord: 152..298
e-value: 1.7E-7
score: 33.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 56..127
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 86..109
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 56..71
NoneNo IPR availablePANTHERPTHR46129FAMILY NOT NAMEDcoord: 48..473
NoneNo IPR availableSUPERFAMILYSSF49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 163..296
NoneNo IPR availableSUPERFAMILYSSF49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 336..472