Potassium voltage-gated channel subfamily KQT member 1

Overview
NamePotassium voltage-gated channel subfamily KQT member 1
Smed IDSMED30033794
Length (bp)3099
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Potassium voltage-gated channel subfamily KQT member 1 (SMED30033794) t-SNE clustered cells

Violin plots show distribution of expression levels for Potassium voltage-gated channel subfamily KQT member 1 (SMED30033794) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Potassium voltage-gated channel subfamily KQT member 1 (SMED30033794) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Potassium voltage-gated channel subfamily KQT member 1 (SMED30033794) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30033794

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
headSMED30033794SMESG000022978.1 SmedASXL_015182SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
neuronSMED30033794SMESG000022978.1 dd_Smed_v4_15923_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
headSMED30033794SMESG000022978.1 dd_Smed_v6_15923_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Human
Match: KCNQ1 (potassium voltage-gated channel subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:6294])

HSP 1 Score: 467.618 bits (1202), Expect = 1.554e-151
Identity = 241/323 (74.61%), Postives = 269/323 (83.28%), Query Frame = 2
Query:  296 VRLDLQRSILNHMNNTQSR---QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            V LD + SI +      +R   Q  +YNFLE PTGWKCF+YHFAVFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   STWKIY
Sbjct:   85 VSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---STWKIY 395          

HSP 2 Score: 142.895 bits (359), Expect = 1.949e-34
Identity = 73/138 (52.90%), Postives = 100/138 (72.46%), Query Frame = 2
Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  481 RTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLS 618          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Human
Match: KCNQ1 (potassium voltage-gated channel subfamily Q member 1 [Source:HGNC Symbol;Acc:HGNC:6294])

HSP 1 Score: 428.328 bits (1100), Expect = 2.905e-138
Identity = 206/264 (78.03%), Postives = 227/264 (85.98%), Query Frame = 2
Query:  464 TIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            TI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   STWKIY
Sbjct:   17 TIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---STWKIY 268          

HSP 2 Score: 142.51 bits (358), Expect = 7.108e-35
Identity = 73/138 (52.90%), Postives = 100/138 (72.46%), Query Frame = 2
Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  354 RTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLS 491          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Human
Match: KCNQ4 (potassium voltage-gated channel subfamily Q member 4 [Source:HGNC Symbol;Acc:HGNC:6298])

HSP 1 Score: 400.208 bits (1027), Expect = 1.211e-125
Identity = 254/610 (41.64%), Postives = 348/610 (57.05%), Query Frame = 2
Query:  311 QRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPD-SNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMA-RRASNSIRRQRP-STLFFPFXXXXXXXXXAGQDTSSN-NDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYV-------RASFSA---VRPRRRKRTISHQEDTEESDSECTALRKPLELTEDH-----KLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGK-PFLRSCQDKRDRT--------RLTVLSRLNRLESQSIKMDSKLDRILLLLSR 2056
            QRS   H    +  Q  +YN LE P GW  F+YH  +FLLV  CL+LSVLSTI  ++E+A   L  +E V+++ FG EY +R+WSAGC  +Y G++GR RFARKP  +ID +V +AS  V+  G++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIF+S+ VYLAE  +N D              F SYAD+LWWG IT+TTIGYGD  P TW+G+++A+ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQ  WR Y+     + L +TW  Y  +           ++    R       E+R A     A  R        RP ST F P           G+ +     D+   G+S +     +Q  APP    +P  P+   +   ATS            R  F A   ++PR        +E  EE   +C       ELT D      K  IR IR ++F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +G+ P  R  ++K D+          ++++ R+ ++E Q   ++ KLD +L   SR
Sbjct:   71 QRSSAAH-KRYRRLQNWVYNVLERPRGW-AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSD--------------FSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCP-----------GESSRMGIKDRIRMGSSQRRTGPSKQHLAPPT---MPTSPSSEQVG-EATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQC-------ELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSR 642          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Human
Match: KCNQ5 (potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299])

HSP 1 Score: 405.601 bits (1041), Expect = 5.566e-125
Identity = 252/610 (41.31%), Postives = 353/610 (57.87%), Query Frame = 2
Query:  269 RQSRMITNAVRLDLQRSILNHMNNTQSR--------QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDT-EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLT----------VLSRLNRLESQSIKMDSKLDRIL 2041
            R+SR      R+ L    L++ ++   R        Q  +YN LE P GW  F+YH  VFL V  CLILSV STI  + ++A + L  +E V+++ FG E+ IR+WSAGC  +Y G++GR+RFARKP  +ID +VL+AS  V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIFSS+ VYL E  +N++              F +YADALWWG IT+TTIGYGD  P TW+G+++++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQC+WR YA    S   +TWK + +    C   +      +S ++ S  F E       RMA     SI+ ++ S                G   S + D      +++G  +K Q+S   N      R  FR            +R   S  +P     T    +D  +E   +C    +  +LT   K  IR IR M+F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +GK  + S  DK+ R ++T          +L R+ ++E Q   ++SKLD +L
Sbjct:   76 RESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGW-AFIYHAFVFLPVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKE--------------FSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSQKLS--FKER-----VRMASPRGQSIKSRQASV---------------GDRRSPSTD-----ITAEGSPTKVQKSWSFND-----RTRFRP----------SLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVE--DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITS--DKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLL 624          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Human
Match: KCNQ5 (potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299])

HSP 1 Score: 405.216 bits (1040), Expect = 7.444e-125
Identity = 253/610 (41.48%), Postives = 354/610 (58.03%), Query Frame = 2
Query:  269 RQSRMITNAVRLDLQRSILNHMNNTQSR--------QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDT-EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLT----------VLSRLNRLESQSIKMDSKLDRIL 2041
            R+SR      R+ L    L++ ++   R        Q  +YN LE P GW  F+YH  VFLLV  CLILSV STI  + ++A + L  +E V+++ FG E+ IR+WSAGC  +Y G++GR+RFARKP  +ID +VL+AS  V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIFSS+ VYL E  +N++              F +YADALWWG IT+TTIGYGD  P TW+G+++++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQC+WR YA    S   +TWK + +    C   +      +S ++ S  F E       RMA     SI+ ++ S                G   S + D      +++G  +K Q+S   N      R  FR            +R   S  +P     T    +D  +E   +C    +  +LT   K  IR IR M+F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +GK  + S  DK+ R ++T          +L R+ ++E Q   ++SKLD +L
Sbjct:   76 RESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGW-AFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKE--------------FSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSQKLS--FKER-----VRMASPRGQSIKSRQASV---------------GDRRSPSTD-----ITAEGSPTKVQKSWSFND-----RTRFRP----------SLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVE--DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITS--DKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLL 624          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Celegans
Match: kqt-3 (Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:B7FAS2])

HSP 1 Score: 430.254 bits (1105), Expect = 4.801e-139
Identity = 213/300 (71.00%), Postives = 253/300 (84.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   20 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 308          

HSP 2 Score: 132.109 bits (331), Expect = 9.514e-32
Identity = 64/101 (63.37%), Postives = 80/101 (79.21%), Query Frame = 2
Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  419 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 519          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Celegans
Match: kqt-3 (Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:B7FAS2])

HSP 1 Score: 430.254 bits (1105), Expect = 4.801e-139
Identity = 213/300 (71.00%), Postives = 253/300 (84.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   20 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 308          

HSP 2 Score: 132.109 bits (331), Expect = 9.514e-32
Identity = 64/101 (63.37%), Postives = 80/101 (79.21%), Query Frame = 2
Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  419 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 519          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Celegans
Match: kqt-3 (Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:B7FAS2])

HSP 1 Score: 430.639 bits (1106), Expect = 1.454e-138
Identity = 213/300 (71.00%), Postives = 253/300 (84.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   61 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 349          

HSP 2 Score: 132.494 bits (332), Expect = 1.258e-31
Identity = 64/101 (63.37%), Postives = 80/101 (79.21%), Query Frame = 2
Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  460 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 560          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Celegans
Match: kqt-3 (Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:B7FAS2])

HSP 1 Score: 430.639 bits (1106), Expect = 1.454e-138
Identity = 213/300 (71.00%), Postives = 253/300 (84.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   61 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 349          

HSP 2 Score: 132.494 bits (332), Expect = 1.258e-31
Identity = 64/101 (63.37%), Postives = 80/101 (79.21%), Query Frame = 2
Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  460 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 560          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Celegans
Match: kqt-3 (Potassium channel, KvQLT family [Source:UniProtKB/TrEMBL;Acc:B7FAS2])

HSP 1 Score: 430.254 bits (1105), Expect = 1.556e-138
Identity = 213/300 (71.00%), Postives = 253/300 (84.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   57 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 345          

HSP 2 Score: 131.724 bits (330), Expect = 1.745e-31
Identity = 64/101 (63.37%), Postives = 80/101 (79.21%), Query Frame = 2
Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  456 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 556          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0299832)

HSP 1 Score: 361.303 bits (926), Expect = 1.924e-111
Identity = 180/300 (60.00%), Postives = 220/300 (73.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   58 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

HSP 2 Score: 93.2041 bits (230), Expect = 5.052e-19
Identity = 62/192 (32.29%), Postives = 107/192 (55.73%), Query Frame = 2
Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  420 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 595          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0299833)

HSP 1 Score: 362.844 bits (930), Expect = 4.619e-111
Identity = 180/300 (60.00%), Postives = 220/300 (73.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   24 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 309          

HSP 2 Score: 93.2041 bits (230), Expect = 6.508e-19
Identity = 62/192 (32.29%), Postives = 107/192 (55.73%), Query Frame = 2
Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  386 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 561          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0310097)

HSP 1 Score: 362.073 bits (928), Expect = 1.074e-110
Identity = 180/300 (60.00%), Postives = 220/300 (73.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   58 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

HSP 2 Score: 92.8189 bits (229), Expect = 7.157e-19
Identity = 62/192 (32.29%), Postives = 107/192 (55.73%), Query Frame = 2
Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  420 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 595          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0310093)

HSP 1 Score: 362.459 bits (929), Expect = 1.394e-110
Identity = 180/300 (60.00%), Postives = 220/300 (73.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   55 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 340          

HSP 2 Score: 92.8189 bits (229), Expect = 8.606e-19
Identity = 62/192 (32.29%), Postives = 107/192 (55.73%), Query Frame = 2
Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  417 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 592          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Fly
Match: KCNQ (gene:FBgn0033494 transcript:FBtr0310094)

HSP 1 Score: 363.229 bits (931), Expect = 1.400e-110
Identity = 180/300 (60.00%), Postives = 220/300 (73.33%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   58 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

HSP 2 Score: 92.8189 bits (229), Expect = 8.134e-19
Identity = 62/192 (32.29%), Postives = 107/192 (55.73%), Query Frame = 2
Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  435 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 610          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Zebrafish
Match: kcnq1.1 (potassium voltage-gated channel, KQT-like subfamily, member 1.1 [Source:ZFIN;Acc:ZDB-GENE-061214-5])

HSP 1 Score: 471.855 bits (1213), Expect = 7.895e-154
Identity = 237/325 (72.92%), Postives = 270/325 (83.08%), Query Frame = 2
Query:  284 ITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYA-VSPDSNLHSTWKIYT 1255
            + +A R  L RS L         Q  +YNFLE PTGWKCF+YHF VFL+VL CLILSVLSTID Y+ +A  TLFWME+VLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL FGS GQVFATSA+RGVRFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D+ N         S F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRC+A ++PDS   +T+K++ 
Sbjct:   61 VYSATRPTLSRSFL---------QGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGN---------SGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDS---ATYKLFV 364          

HSP 2 Score: 129.028 bits (323), Expect = 2.812e-30
Identity = 77/166 (46.39%), Postives = 106/166 (63.86%), Query Frame = 2
Query: 1682 DTEESDSECTALRKPL----ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL----LLLSRIASCSI---NNQRSSHFRSDACPTHSVYNSS 2140
            D  E++ E   +  P+    +L + H+ AIRVI+RM +F+A ++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+D S+GK   F  S +  +D+   T+ SRLNR++ +   MD  L+ I     L+L+R     +     QRS+  R  A  + SV +SS
Sbjct:  465 DDMETEPEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNSIAESLNLMLARERRGDLARGKEQRSTMRRQSATFSLSVLDSS 630          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Zebrafish
Match: kcnq1.1 (potassium voltage-gated channel, KQT-like subfamily, member 1.1 [Source:ZFIN;Acc:ZDB-GENE-061214-5])

HSP 1 Score: 471.855 bits (1213), Expect = 8.886e-154
Identity = 237/325 (72.92%), Postives = 270/325 (83.08%), Query Frame = 2
Query:  284 ITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYA-VSPDSNLHSTWKIYT 1255
            + +A R  L RS L         Q  +YNFLE PTGWKCF+YHF VFL+VL CLILSVLSTID Y+ +A  TLFWME+VLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL FGS GQVFATSA+RGVRFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D+ N         S F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRC+A ++PDS   +T+K++ 
Sbjct:   61 VYSATRPTLSRSFL---------QGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGN---------SGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDS---ATYKLFV 364          

HSP 2 Score: 129.028 bits (323), Expect = 2.846e-30
Identity = 77/166 (46.39%), Postives = 106/166 (63.86%), Query Frame = 2
Query: 1682 DTEESDSECTALRKPL----ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL----LLLSRIASCSI---NNQRSSHFRSDACPTHSVYNSS 2140
            D  E++ E   +  P+    +L + H+ AIRVI+RM +F+A ++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+D S+GK   F  S +  +D+   T+ SRLNR++ +   MD  L+ I     L+L+R     +     QRS+  R  A  + SV +SS
Sbjct:  477 DDMETEPEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNSIAESLNLMLARERRGDLARGKEQRSTMRRQSATFSLSVLDSS 642          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Zebrafish
Match: kcnq1.1 (potassium voltage-gated channel, KQT-like subfamily, member 1.1 [Source:ZFIN;Acc:ZDB-GENE-061214-5])

HSP 1 Score: 461.07 bits (1185), Expect = 5.140e-152
Identity = 237/324 (73.15%), Postives = 270/324 (83.33%), Query Frame = 2
Query:  284 ITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYA-VSPDSNLHSTWKIY 1252
            + +A R  L RS L         Q  +YNFLE PTGWKCF+YHF VFL+VL CLILSVLSTID Y+ +A  TLFWME+VLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL FGS GQVFATSA+RGVRFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D+ N         S F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRC+A ++PDS   +T+K++
Sbjct:   61 VYSATRPTLSRSFL---------QGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGN---------SGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDS---ATYKLF 363          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Zebrafish
Match: kcnq1.2 (potassium voltage-gated channel, KQT-like subfamily, member 1.2 [Source:ZFIN;Acc:ZDB-GENE-130530-935])

HSP 1 Score: 432.18 bits (1110), Expect = 3.784e-140
Identity = 227/303 (74.92%), Postives = 255/303 (84.16%), Query Frame = 2
Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            S Q  +YNFLE P G +CFLYHF VFL+VL+CLI SVLSTI+ Y + A  +LFWMEIVLV+FFG EY +RLWSAGCRSKY+G +GR+RF RKPIS+IDL+V++AS VVL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+ +   F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWK+Y 
Sbjct:  115 SMQGDVYNFLERPAGLRCFLYHFLVFLMVLVCLIFSVLSTIEQYADFATGSLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIKGRLRFIRKPISIIDLIVVVASVVVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGKTG-FSSYADALWWGVVTVTTIGYGDKVPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYACEKSDSCTATWKMYV 408          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Zebrafish
Match: kcnq2b (potassium voltage-gated channel, KQT-like subfamily, member 2b [Source:ZFIN;Acc:ZDB-GENE-120130-1])

HSP 1 Score: 339.347 bits (869), Expect = 1.563e-101
Identity = 170/301 (56.48%), Postives = 221/301 (73.42%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPD-SNLHSTWKIY 1252
            Q  +YN LE P GW  F+YH  VFLLV  CL+LSV STI  Y + + + L+ +EIV ++ FG EY +R+WSAGC  +Y G+RGR++FARKP  +ID++VL+AS  VL  G++G VFATSAIR +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LI +S+ VYLAE + NE               F++YADALWWG+IT+TTIGYGD  P TW G+++A+ F++  +SFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQ  WR YA + + ++L+STW  Y
Sbjct:   78 QNFLYNVLERPRGW-AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEDALYILEIVTIVVFGVEYIVRIWSAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASISVLAAGTQGNVFATSAIRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAEKEDNE--------------MFETYADALWWGLITLTTIGYGDKYPITWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQAAWRFYATNLNRTDLYSTWDYY 363          

HSP 2 Score: 92.4337 bits (228), Expect = 1.340e-18
Identity = 47/125 (37.60%), Postives = 76/125 (60.80%), Query Frame = 2
Query: 1679 EDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTR-------LTVLSRLNRLESQSIKMDSKLD 2032
            ED  + +  C     P +LT   K+ IR +  M+F +++R+F+++ +PYDV DVIEQYS GHL+M+ RIK LQ R+DQ +G+    + +D+   T         +++ RL ++E Q + M+ KLD
Sbjct:  487 EDIVDDNKSCHCEFVPQDLTPGLKVTIRAVCIMRFMVSKRKFKESLRPYDVMDVIEQYSAGHLDMLARIKNLQSRVDQIVGRGAPITDKDRPKGTTDGELPEDPSMMGRLGKVEKQVMSMERKLD 611          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Xenopus
Match: ENSXETT00000046823.1 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:100492908])

HSP 1 Score: 470.7 bits (1210), Expect = 8.323e-156
Identity = 238/308 (77.27%), Postives = 261/308 (84.74%), Query Frame = 2
Query:  329 HMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            H     S Q  IYNFLE P+GW+CF+YHF+VFLLVLICLI SVLSTI+HY E A  TLFWMEIVLV+FFG EY IRLWSAGCRSKY+GF+GRIRFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+     F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWKIY
Sbjct:   78 HYLTRTSMQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGRTG-FSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIY 376          

HSP 2 Score: 110.153 bits (274), Expect = 1.329e-24
Identity = 49/62 (79.03%), Postives = 57/62 (91.94%), Query Frame = 2
Query: 1718 RKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR 1903
            RK + LTE H++A++V RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR
Sbjct:  396 RKQVRLTEAHRMAVKVTRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR 457          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Xenopus
Match: ENSXETT00000046791.1 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:100492908])

HSP 1 Score: 476.478 bits (1225), Expect = 2.021e-155
Identity = 238/308 (77.27%), Postives = 261/308 (84.74%), Query Frame = 2
Query:  329 HMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            H     S Q  IYNFLE P+GW+CF+YHF+VFLLVLICLI SVLSTI+HY E A  TLFWMEIVLV+FFG EY IRLWSAGCRSKY+GF+GRIRFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+     F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWKIY
Sbjct:   78 HYLTRTSMQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGRTG-FSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIY 376          

HSP 2 Score: 147.132 bits (370), Expect = 6.280e-36
Identity = 75/132 (56.82%), Postives = 95/132 (71.97%), Query Frame = 2
Query: 1661 RTISHQEDTE--ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            RT S+ +D +    +S   A+    +LTE H++A++V RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D S+GKP L   +   D+   TV SRL RLE +  +MD KLD IL + 
Sbjct:  479 RTNSYTDDIDGISEESALPAVTDLSQLTEAHRMAVKVTRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHSLGKPGLFLPEKGVDKGYYTVGSRLMRLEEKVNRMDHKLDEILCVF 610          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Xenopus
Match: ENSXETT00000046831.1 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:100492908])

HSP 1 Score: 464.537 bits (1194), Expect = 8.280e-155
Identity = 236/308 (76.62%), Postives = 261/308 (84.74%), Query Frame = 2
Query:  329 HMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            H     S Q  IYNFLE P+GW+CF+YHF+VFLLVLICLI SVLSTI+HY E A  TLFWMEIVLV+FFG EY IRLWSAGCRSKY+GF+GRIRFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + ++            + F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWKIY
Sbjct:   49 HYLTRTSMQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDEEGR---------TGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIY 347          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Xenopus
Match: ENSXETT00000046772.1 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:100492908])

HSP 1 Score: 475.707 bits (1223), Expect = 1.126e-154
Identity = 238/308 (77.27%), Postives = 261/308 (84.74%), Query Frame = 2
Query:  329 HMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            H     S Q  IYNFLE P+GW+CF+YHF+VFLLVLICLI SVLSTI+HY E A  TLFWMEIVLV+FFG EY IRLWSAGCRSKY+GF+GRIRFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+     F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWKIY
Sbjct:   78 HYLTRTSMQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGRTG-FSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIY 376          

HSP 2 Score: 144.05 bits (362), Expect = 8.946e-35
Identity = 69/106 (65.09%), Postives = 83/106 (78.30%), Query Frame = 2
Query: 1733 LTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            LTE H++A++V RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D S+GKP L   +   D+   TV SRL RLE +  +MD KLD IL + 
Sbjct:  545 LTEAHRMAVKVTRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHSLGKPGLFLPEKGVDKGYYTVGSRLMRLEEKVNRMDHKLDEILCVF 650          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Xenopus
Match: kri1 (KRI1 homolog [Source:Xenbase;Acc:XB-GENE-6036517])

HSP 1 Score: 460.299 bits (1183), Expect = 1.602e-151
Identity = 246/362 (67.96%), Postives = 280/362 (77.35%), Query Frame = 2
Query:  194 DKLENDEDRDEDYLLTKRKSELEKRRQSRMITN----AVRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISY-FKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            D   N + R +     ++    E +R++ + T+     + LD + SI +      +R  I   +YNFLE PTGWKCF+YHF VFL+VLICLI SVLSTI  Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE          K   DS   Y F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY
Sbjct:   49 DGSSNGQQRQD-----RQADTFELKRETLVTTDPPRPTINLDPRVSIYSGRRPLLTRTNIQGRVYNFLERPTGWKCFVYHFTVFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVLVVFFGAEYVVRLWSAGCRSKYVGIWGRLRFARKPISVIDLIVVVASIIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----------KDAIDSSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIY 392          

HSP 2 Score: 103.219 bits (256), Expect = 2.542e-22
Identity = 46/58 (79.31%), Postives = 54/58 (93.10%), Query Frame = 2
Query: 1733 LTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRM 1906
            L E H+ AI+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR 
Sbjct:  430 LKEHHRAAIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRF 487          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Mouse
Match: Kcnq1 (potassium voltage-gated channel, subfamily Q, member 1 [Source:MGI Symbol;Acc:MGI:108083])

HSP 1 Score: 468.003 bits (1203), Expect = 5.120e-152
Identity = 239/324 (73.77%), Postives = 268/324 (82.72%), Query Frame = 2
Query:  296 VRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            V LD + SI +      +R  I   +YNFLE PTGWKCF+YHF VFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY 
Sbjct:   84 VSLDPRVSIYSARRPLLARTHIQGRVYNFLERPTGWKCFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRIE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYV 395          

HSP 2 Score: 141.354 bits (355), Expect = 4.525e-34
Identity = 72/138 (52.17%), Postives = 100/138 (72.46%), Query Frame = 2
Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L + H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  480 RTNSFAEDLDLEGETLLTPITHVSQLRDHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIPISEKSKDRGSNTIGARLNRVEDKVTQLDQRLVIITDMLHQLLS 617          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Mouse
Match: Kcnq1 (potassium voltage-gated channel, subfamily Q, member 1 [Source:MGI Symbol;Acc:MGI:108083])

HSP 1 Score: 457.988 bits (1177), Expect = 1.918e-151
Identity = 239/324 (73.77%), Postives = 268/324 (82.72%), Query Frame = 2
Query:  296 VRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            V LD + SI +      +R  I   +YNFLE PTGWKCF+YHF VFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY 
Sbjct:   20 VSLDPRVSIYSARRPLLARTHIQGRVYNFLERPTGWKCFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRIE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYV 331          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Mouse
Match: Kcnq5 (potassium voltage-gated channel, subfamily Q, member 5 [Source:MGI Symbol;Acc:MGI:1924937])

HSP 1 Score: 402.905 bits (1034), Expect = 3.721e-124
Identity = 246/574 (42.86%), Postives = 342/574 (59.58%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDT-EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLT----------VLSRLNRLESQSIKMDSKLDRIL 2041
            Q  +YN LE P GW  F+YH  VFLLV  CLILSV STI  + ++A + L  +E V+++ FG E+ IR+WSAGC  +Y G++GR+RFARKP  +ID +VL+AS  V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIFSS+ VYL E  +N++              F +YADALWWG IT+TTIGYGD  P TW+G+++++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQC+WR YA    S   +TWK + +    C   +      +S ++ S  F E       RMA     SI+ ++ S                G   S + D      +++G  +K Q+S   N      R  FR            +R   S  +P     T    +D  +E   +C    +  +LT   K  IR IR M+F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +GK  + S  DK+ R ++T          +L+R+ ++E Q   ++SKLD +L
Sbjct:  113 QNYLYNVLERPRGW-AFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKE--------------FSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSQKLS--FKER-----VRMASPRGQSIKSRQASV---------------GDRRSPSTD-----ITAEGSPTKVQKSWSFND-----RTRFRP----------SLRLKSSQPKPVIDADTALGIDDVYDEKGCQCDVSVE--DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTS--DKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLL 625          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Mouse
Match: Kcnq5 (potassium voltage-gated channel, subfamily Q, member 5 [Source:MGI Symbol;Acc:MGI:1924937])

HSP 1 Score: 402.519 bits (1033), Expect = 6.452e-124
Identity = 249/586 (42.49%), Postives = 347/586 (59.22%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSH---FF------SEMRNASFK---RMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDT-EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLT----------VLSRLNRLESQSIKMDSKLDRIL 2041
            Q  +YN LE P GW  F+YH  VFLLV  CLILSV STI  + ++A + L  +E V+++ FG E+ IR+WSAGC  +Y G++GR+RFARKP  +ID +VL+AS  V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIFSS+ VYL E  +N++              F +YADALWWG IT+TTIGYGD  P TW+G+++++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQC+WR YA    S   +TWK + +    C   +      +S +  S+   FF       + +  SFK   RMA     SI+ ++ S                G   S + D      +++G  +K Q+S   N      R  FR            +R   S  +P     T    +D  +E   +C    +  +LT   K  IR IR M+F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +GK  + S  DK+ R ++T          +L+R+ ++E Q   ++SKLD +L
Sbjct:  113 QNYLYNVLERPRGW-AFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKE--------------FSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSKFCSNKQKFFRVYTSRKQSQKLSFKERVRMASPRGQSIKSRQASV---------------GDRRSPSTD-----ITAEGSPTKVQKSWSFND-----RTRFRP----------SLRLKSSQPKPVIDADTALGIDDVYDEKGCQCDVSVE--DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTS--DKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLL 644          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Mouse
Match: Kcnq2 (potassium voltage-gated channel, subfamily Q, member 2 [Source:MGI Symbol;Acc:MGI:1309503])

HSP 1 Score: 397.512 bits (1020), Expect = 4.883e-123
Identity = 241/578 (41.70%), Postives = 341/578 (59.00%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVS-PDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSS-QGETSKEQESA------PPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTR----------LTVLSRLNRLESQSIKMDSKLD 2032
            Q  +YN LE P GW  F+YH  VFLLV  CL+LSV STI  Y + +   L+ +EIV ++ FG EY +R+W+AGC  +Y G+RGR++FARKP  +ID++VL+AS  VL  GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +EL+T  YIGFL LI +S+ VYLAE   N+              +F +YADALWWG+IT+TTIGYGD  P+TW G+++A+ F++  +SFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQ  WR YA +   ++LHSTW+ Y +  +           G      S     +      R  +  S    R+ P     P  + S       +  SS      +G  S Q +T +   SA       P+ +P       RS +  A       R   +A R    + ++  ++  E++ S C       +LT   K++IR +  M+F +++R+F+++ +PYDV DVIEQYS GHL+M+ RIK LQ R+DQ +G+    +  DK DRT+           +++ RL ++E Q + M+ KLD
Sbjct:   78 QNFLYNVLERPRGW-AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND--------------HFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGA-----SRLIPPLNQLELLRNLKSKSGLTFRKEPQ----PEPSPSQKVSLKDRVFSSPRGMAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRTRQA------FRIKGAASRQNSEEASLPGEDIVEDNKS-CNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRG--PTITDK-DRTKGPAETELPEDPSMMGRLGKVEKQVLSMEKKLD 621          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. UniProt/SwissProt
Match: sp|O70344|KCNQ1_CAVPO (Potassium voltage-gated channel subfamily KQT member 1 OS=Cavia porcellus OX=10141 GN=KCNQ1 PE=2 SV=3)

HSP 1 Score: 469.929 bits (1208), Expect = 7.470e-152
Identity = 241/324 (74.38%), Postives = 268/324 (82.72%), Query Frame = 2
Query:  296 VRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            V LD + SI +      +R  I   +YNFLE PTGWKCF+YHFAVFL+VL CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   STWKIY 
Sbjct:   86 VSLDPRVSIYSARRPLLARTHIQGRVYNFLERPTGWKCFVYHFAVFLIVLACLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---STWKIYV 397          

HSP 2 Score: 143.665 bits (361), Expect = 5.284e-34
Identity = 75/145 (51.72%), Postives = 102/145 (70.34%), Query Frame = 2
Query: 1640 VRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            V P    RT S  ED + E ++  T +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  475 VSPTHFMRTNSFAEDLDLEGETLLTPITHVSQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIPISEKSKDRGSNTIGARLNRVEDKVTQLDQRLVVITDMLHQLLS 619          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. UniProt/SwissProt
Match: sp|P70057|KCNQ1_XENLA (Potassium voltage-gated channel subfamily KQT member 1 OS=Xenopus laevis OX=8355 GN=kcnq1 PE=1 SV=2)

HSP 1 Score: 468.003 bits (1203), Expect = 2.431e-151
Identity = 248/354 (70.06%), Postives = 279/354 (78.81%), Query Frame = 2
Query:  218 RDEDYLLTKRKSELEKRRQSRMITNAVR----LDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISY-FKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            R ED    ++ +  E +R++ + T+  R    LD + SI +      SR  I   +YNFLE PTGWKCF+YHF VFL+VLICLI SVLSTI  Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE          K   DS   Y F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY
Sbjct:   49 RQED----RQANSFELKRETLVATDPPRPTINLDPRVSIYSGRRPLLSRTNIQGRVYNFLERPTGWKCFVYHFTVFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVLVVFFGAEYVVRLWSAGCRSKYVGVWGRLRFARKPISVIDLIVVVASVIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----------KDAIDSSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIY 385          

HSP 2 Score: 148.288 bits (373), Expect = 1.281e-35
Identity = 84/167 (50.30%), Postives = 110/167 (65.87%), Query Frame = 2
Query: 1619 VRASFSAVRPRRRK--RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIASCSINNQRSSHFRS 2104
            VR  F  + P      RT S  +D + E D+  T +    EL E H+ AI+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQS+GKP  FL      +D+   T+ SRLNR+E +  +MD KL+ I  +L  + +   N Q S   R+
Sbjct:  454 VRKPFGFLDPSTGPFIRTSSFTDDLDMEGDTLLTPITHISELKEHHRAAIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKPSLFLSVSDKVKDKGINTIGSRLNRVEDKVTQMDHKLNLITDMLHHLLT---NQQGSQSIRT 617          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. UniProt/SwissProt
Match: sp|P97414|KCNQ1_MOUSE (Potassium voltage-gated channel subfamily KQT member 1 OS=Mus musculus OX=10090 GN=Kcnq1 PE=1 SV=3)

HSP 1 Score: 468.003 bits (1203), Expect = 3.581e-151
Identity = 239/324 (73.77%), Postives = 268/324 (82.72%), Query Frame = 2
Query:  296 VRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            V LD + SI +      +R  I   +YNFLE PTGWKCF+YHF VFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY 
Sbjct:   84 VSLDPRVSIYSARRPLLARTHIQGRVYNFLERPTGWKCFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRIE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYV 395          

HSP 2 Score: 141.354 bits (355), Expect = 3.165e-33
Identity = 72/138 (52.17%), Postives = 100/138 (72.46%), Query Frame = 2
Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L + H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  480 RTNSFAEDLDLEGETLLTPITHVSQLRDHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIPISEKSKDRGSNTIGARLNRVEDKVTQLDQRLVIITDMLHQLLS 617          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. UniProt/SwissProt
Match: sp|O97531|KCNQ1_FELCA (Potassium voltage-gated channel subfamily KQT member 1 (Fragment) OS=Felis catus OX=9685 GN=KCNQ1 PE=2 SV=2)

HSP 1 Score: 464.537 bits (1194), Expect = 4.789e-151
Identity = 233/299 (77.93%), Postives = 258/299 (86.29%), Query Frame = 2
Query:  362 IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            +YNFLE PTGWKCF+YHFAVFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V+LAS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +P+S   STW IY 
Sbjct:   21 VYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYVALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGVWGRLRFARKPISIIDLIVVLASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGQVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPES---STWNIYV 307          

HSP 2 Score: 141.739 bits (356), Expect = 1.157e-33
Identity = 72/138 (52.17%), Postives = 99/138 (71.74%), Query Frame = 2
Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++    +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  392 RTNSVAEDLDLEGETPLVPITHVSQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVAQLDQRLVLITDMLQQLLS 529          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. UniProt/SwissProt
Match: sp|P51787|KCNQ1_HUMAN (Potassium voltage-gated channel subfamily KQT member 1 OS=Homo sapiens OX=9606 GN=KCNQ1 PE=1 SV=3)

HSP 1 Score: 467.618 bits (1202), Expect = 7.465e-151
Identity = 241/323 (74.61%), Postives = 269/323 (83.28%), Query Frame = 2
Query:  296 VRLDLQRSILNHMNNTQSR---QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            V LD + SI +      +R   Q  +YNFLE PTGWKCF+YHFAVFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   STWKIY
Sbjct:   85 VSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---STWKIY 395          

HSP 2 Score: 142.895 bits (359), Expect = 9.359e-34
Identity = 73/138 (52.90%), Postives = 100/138 (72.46%), Query Frame = 2
Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  481 RTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLS 618          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. TrEMBL
Match: X1YV70 (Uncharacterized protein OS=Capitella teleta OX=283909 PE=3 SV=1)

HSP 1 Score: 616.69 bits (1589), Expect = 0.000e+0
Identity = 344/570 (60.35%), Postives = 404/570 (70.88%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTIS-HQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRI 2059
            Q  +YNFLE PTGWKCF+YHF VF++VLICLI SVLSTID Y   A  TLFWMEIVLV+FFG EY IRLWSAGCRSKYMG RGR RFARKPIS+IDL+V++AS VVL  GS GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAE  +       KS+E +  + F SYADALWWGVITVTTIGYGD VP+TW+GKI+ASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYA  P S   +TW+I+T                ++ R +        +++F + ARRAS  I+++R S   F           +G      +D+ G    S+G            F P   R +  S +  A    G  R    A R  +    ++  + D+  SDS    L   L LTE HK AIRVIRR+++F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP       +RD+ ++T+++RL R+E+Q  K+D KLD +L LL+ I
Sbjct:   77 QGKVYNFLERPTGWKCFMYHFTVFMMVLICLIFSVLSTIDQYESFANETLFWMEIVLVVFFGLEYLIRLWSAGCRSKYMGARGRFRFARKPISIIDLIVVVASIVVLSVGSNGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAEKDA-------KSEEGT--TDFTSYADALWWGVITVTTIGYGDTVPQTWMGKIVASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAAEPRSLFLATWRIHT---------------QDAPRHHG-------SSAFIKAARRAS-LIKKRRFSKNRFDL---------SGSANHVASDRKG----SEGSIV---------FAPDESRTSSISGNHNALRRPGGRRDGTGAGRTEQTSAIVNISRIDSSTSDS----LSPRLTLTEAHKTAIRVIRRIRYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGAWMVSSERDKQKVTIVARLARVENQVNKIDQKLDSVLHLLNSI 588          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. TrEMBL
Match: A0A2S1WM53 (Putative potassium voltage-gated channel subfamily KQT 2 OS=Hirudo verbana OX=311461 PE=2 SV=1)

HSP 1 Score: 609.757 bits (1571), Expect = 0.000e+0
Identity = 331/575 (57.57%), Postives = 398/575 (69.22%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMR-NASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFR---SLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            Q  +YNFLE PTGWKCF YHF VF +VLICLI SVLSTID Y + A  +LFWMEIVLV+FFG EY +RLWSAGCRSKYM F GR+RFARKPIS+IDL+V+  S +VL FGS GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAE  +N          D + S F SYADALWWGV+TVTTIGYGD VP+TW+G+I+ASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAAT+IQCLWRC+A        +TW                           HF  E R + S   MARRAS +  ++R S         ++     G  T  NN       ++ G + +  + +       P +P      SL     S   +++             T+  +  T+  D++     +PL+LT  HK AIRVIRR+++F+A+R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP +   ++K DR +LT+++RL+R+E+Q  KMD+KL+ IL LL+ + S
Sbjct:   51 QGRVYNFLERPTGWKCFAYHFTVFAMVLICLIFSVLSTIDQYEDFANESLFWMEIVLVVFFGFEYVVRLWSAGCRSKYMSFHGRLRFARKPISIIDLIVVTGSLIVLSFGSNGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAEKDAN----------DGKSSDFTSYADALWWGVVTVTTIGYGDTVPQTWIGRIVASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATIIQCLWRCHAAETHFRSQATWS-------------------------GHFLRENRPHLSLANMARRASATFVKRRRSAQKNSLEMPATGADHQGLQT--NNFLTVDAAATNGCSFRASDESILCSSGNPAKPTAEDTVSLRPVPNSAGMFLKVP-----------TLVPESSTDVDDADSAT--RPLQLTVAHKSAIRVIRRIKYFVAKRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGIMVSEEK-DRQKLTIIARLSRVENQIEKMDTKLEDILGLLNTVVS 574          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. TrEMBL
Match: A0A433SVX0 (Uncharacterized protein (Fragment) OS=Elysia chlorotica OX=188477 GN=EGW08_018780 PE=3 SV=1)

HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0
Identity = 337/573 (58.81%), Postives = 388/573 (67.71%), Query Frame = 2
Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNAS-FKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAV---RPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLS 2053
            S Q  +YNFLE PTGWKCF+YHF VF++VLICLI SVLSTI  Y + A  TLFWMEIVLV+FFG EY IRLWSAGCRSKYMG RGR RFARKPIS+ID  V++AS VVL  GS GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAE  S ED              F SYADALWWGVITVTTIGYGD VPKTW+G+I+ASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP AATLIQCLWRC+A  P+ +  +TWKI+ Q                  + Y    +   ++S   RMAR+AS   +R+                            +N  GTSS G   + QES                             AS SAV    PR      + +   E+ D     + KP +LT+ HK  IRVIR+++FF+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ+IGKP      + RD+ +LT+ SR+ R+E+Q  KMD K+D+ ++LL+
Sbjct:    3 SLQVKVYNFLERPTGWKCFIYHFTVFMMVLICLIFSVLSTIQQYTDFANETLFWMEIVLVVFFGLEYVIRLWSAGCRSKYMGLRGRFRFARKPISIIDFTVVVASIVVLSAGSNGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAEKDSGED--------------FTSYADALWWGVITVTTIGYGDTVPKTWMGRIVASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPTAATLIQCLWRCHAAEPNVSSTATWKIHIQE-----------------KNYKMLVNNSTSSSALTRMARKASLLKKRK--------------------------GMRNSLGTSSGG--LERQESM----------------------------ASLSAVDMGTPRHS----AGKNSMEDDDDFDDLIFKPEQLTDGHKAMIRVIRKIKFFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTIGKPVYHG--NMRDKEKLTLCSRIGRIEAQVTKMDHKMDQTIVLLN 482          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. TrEMBL
Match: A0A210QEF2 (Potassium voltage-gated channel subfamily KQT member 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT07127 PE=3 SV=1)

HSP 1 Score: 595.119 bits (1533), Expect = 0.000e+0
Identity = 318/567 (56.08%), Postives = 389/567 (68.61%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLS 2053
            Q  +YNFLE PTGWKCF+YHF VF++VLICLI SVLSTID Y   A+ TL++MEIVLV FFG EY +RLWSAGCRSKYMG +GRIRFARKPIS+IDL+V++AS  V   GS+GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSV+Y+HRQELITTLYIGFLGLIFSSYFVYLAE     D+             F SYADALWWGVITV TIGYGD VP+TW+GKI+ASCF+VFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQC+WRCYA  P SN  +TWKI+                           S        RMARRAS ++R++R S +     + S       +  +S   ++  GT      S  ++S+ PN +             +    +G                   + +  ++ + +   + K ++LT+ HK AIRV+R++++F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP        +DR R+T+ +R+ R+E+Q  K D KLD+++ LL+
Sbjct:   87 QAQLYNFLERPTGWKCFIYHFTVFMMVLICLIFSVLSTIDQYAGFAMETLYYMEIVLVCFFGVEYVVRLWSAGCRSKYMGMKGRIRFARKPISIIDLIVVVASIGVFSVGSEGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVIYLHRQELITTLYIGFLGLIFSSYFVYLAERDEGRDD-------------FSSYADALWWGVITVMTIGYGDKVPQTWMGKIVASCFAVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCVWRCYAADPTSNSEATWKIHIHD------------------------SSNEETMLARMARRASLTLRKRRSSRM----DSISIGNHVRRESLTSFYQEDKIGTPR----SNRRDSSRPNMM-------------SNHPNVG------------------GNDQYEDQMEYDLDDVEKVVQLTDAHKTAIRVLRKIKYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGTLYSNCYKDRERMTIGARIVRMETQMQKTDQKLDQVIFLLN 577          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. TrEMBL
Match: A0A2T7P771 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_11871 PE=3 SV=1)

HSP 1 Score: 590.112 bits (1520), Expect = 0.000e+0
Identity = 317/557 (56.91%), Postives = 376/557 (67.50%), Query Frame = 2
Query:  335 NNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQ 2005
            N+ QSR   +YNFLE PTGWKCF+YHF VF++VLICLI SVLSTID Y + A+ TLFWMEI LV FFG EY IRLWSAGCRSKYMG RGR RF+RKPIS+IDL+V++AS VV   GS+GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSV+Y+HRQELITTLYIGFLGLIFSSYFVYLAE    E ++            FKSYADALWWGVITV TIGYGD VP+TW+GKI+ASCF+VFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A +P S   +TWKI+                                  F +MARRAS ++R++R S L                D+SS    +     S    +   E   P    +  R + R   C A                        +  + +  +    ++ K ++LTE HK AIRVIR++++F++ RRFQ  RKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP        RDR ++T+ +R+ R+E+Q
Sbjct:   95 NSIQSR---VYNFLERPTGWKCFIYHFTVFMMVLICLIFSVLSTIDQYTKFAMETLFWMEIFLVCFFGAEYVIRLWSAGCRSKYMGIRGRFRFSRKPISIIDLIVVVASIVVFTVGSEGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVIYLHRQELITTLYIGFLGLIFSSYFVYLAERGEEERDD------------FKSYADALWWGVITVMTIGYGDKVPQTWMGKIVASCFAVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAAAPGSKSEATWKIHVHDPGS------------------------EETMFAKMARRASLTLRKRRMSRL----------------DSSSTVANHSVYRESVSSITYADEKPGPLTPRILRRDSHRPSICGAN----------------------ENNYNDDTDNDLDDSMEKVVQLTEAHKTAIRVIRKIKYFVSRRRFQATRKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPSNLYSSQARDREKMTIGARMVRVENQ 574          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Cavefish
Match: kcnq1.1 (potassium voltage-gated channel subfamily Q member 1 [Source:NCBI gene;Acc:103046994])

HSP 1 Score: 565.459 bits (1456), Expect = 0.000e+0
Identity = 321/617 (52.03%), Postives = 413/617 (66.94%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFP-FXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPP-NFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGK-PFLRSCQDK-RDRTRLTVLSRLNRLESQSIKMDSKLDRIL-----LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSS 2170
            Q  +YNFLE P+GWKCF+YHF VFL+VL CLILSVLSTI+ Y+ +A +TLFW+EIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIF+SYFVYLAE  + + +          ++ F SYADALWWGV+TVTTIGYGD VP+TW+GK I SCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+A+ +PDS   ST+K++ +      +P                 S  +     +M R+   S +   PS+   P  + +   G    QDT  + D +G     + +  +   S     F P P++          + GI  +++      P +R  + +   + E E DS    +    +L E H+ AIRVI+RM++F+A++RFQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQS+GK    ++  D+ +D+   T+ SRLNR+E +   MD  L+ I      LL+       +     S   S++ P++   +++T P   ++SS
Sbjct:   86 QGRVYNFLERPSGWKCFVYHFTVFLIVLSCLILSVLSTIEEYQTLAQDTLFWVEIVLVVFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISIIDLIVVVASVIVLSVGSNGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLALIFASYFVYLAEKDAVDGDG---------VTEFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIGSCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTSWRCFAIENPDS---STYKMFVRRKPMTAHPSA---------------SSPKAKKTVKMRRKVKTSEKDNGPSSPTIPTITYDFDEGRDPSQDTVYSTDMSGAAALRRLDRQQSWTSITSFQFSPPPVK---------KSPGILEIQSH----PPLQRNSSFADDLELEAERDSILLPVTHVSQLRESHRAAIRVIQRMRYFVAKKRFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKITLFQTGSDRAKDKGLNTIGSRLNRMEEKITHMDKTLNCIAESLNSLLMRDSGRIGLAEAGPSLSASNSLPSYDQLSTTTFPSALEESS 662          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Cavefish
Match: kcnq1.1 (potassium voltage-gated channel subfamily Q member 1 [Source:NCBI gene;Acc:103046994])

HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0
Identity = 321/617 (52.03%), Postives = 413/617 (66.94%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFP-FXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPP-NFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGK-PFLRSCQDK-RDRTRLTVLSRLNRLESQSIKMDSKLDRIL-----LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSS 2170
            Q  +YNFLE P+GWKCF+YHF VFL+VL CLILSVLSTI+ Y+ +A +TLFW+EIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIF+SYFVYLAE  + + +          ++ F SYADALWWGV+TVTTIGYGD VP+TW+GK I SCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+A+ +PDS   ST+K++ +      +P                 S  +     +M R+   S +   PS+   P  + +   G    QDT  + D +G     + +  +   S     F P P++          + GI  +++      P +R  + +   + E E DS    +    +L E H+ AIRVI+RM++F+A++RFQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQS+GK    ++  D+ +D+   T+ SRLNR+E +   MD  L+ I      LL+       +     S   S++ P++   +++T P   ++SS
Sbjct:   61 QGRVYNFLERPSGWKCFVYHFTVFLIVLSCLILSVLSTIEEYQTLAQDTLFWVEIVLVVFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISIIDLIVVVASVIVLSVGSNGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLALIFASYFVYLAEKDAVDGDG---------VTEFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIGSCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTSWRCFAIENPDS---STYKMFVRRKPMTAHPSA---------------SSPKAKKTVKMRRKVKTSEKDNGPSSPTIPTITYDFDEGRDPSQDTVYSTDMSGAAALRRLDRQQSWTSITSFQFSPPPVK---------KSPGILEIQSH----PPLQRNSSFADDLELEAERDSILLPVTHVSQLRESHRAAIRVIQRMRYFVAKKRFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKITLFQTGSDRAKDKGLNTIGSRLNRMEEKITHMDKTLNCIAESLNSLLMRDSGRIGLAEAGPSLSASNSLPSYDQLSTTTFPSALEESS 637          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Cavefish
Match: kcnq1.1 (potassium voltage-gated channel subfamily Q member 1 [Source:NCBI gene;Acc:103046994])

HSP 1 Score: 563.918 bits (1452), Expect = 0.000e+0
Identity = 322/616 (52.27%), Postives = 413/616 (67.05%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFP-FXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGK-PFLRSCQDK-RDRTRLTVLSRLNRLESQSIKMDSKLDRIL-----LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSS 2170
            Q  +YNFLE P+GWKCF+YHF VFL+VL CLILSVLSTI+ Y+ +A +TLFW+EIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIF+SYFVYLAE  + + +          ++ F SYADALWWGV+TVTTIGYGD VP+TW+GK I SCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+A+ +PDS   ST+K++ +      +P                 S  +     +M R+   S +   PS+   P  + +   G    QDT  + D + +  S    TS +       F P P++          + GI  +++      P +R  + +   + E E DS    +    +L E H+ AIRVI+RM++F+A++RFQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQS+GK    ++  D+ +D+   T+ SRLNR+E +   MD  L+ I      LL+       +     S   S++ P++   +++T P   ++SS
Sbjct:   86 QGRVYNFLERPSGWKCFVYHFTVFLIVLSCLILSVLSTIEEYQTLAQDTLFWVEIVLVVFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISIIDLIVVVASVIVLSVGSNGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLALIFASYFVYLAEKDAVDGDG---------VTEFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIGSCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTSWRCFAIENPDS---STYKMFVRRKPMTAHPSA---------------SSPKAKKTVKMRRKVKTSEKDNGPSSPTIPTITYDFDEGRDPSQDTVYSTDMSDRQQSWTSITSFQ-------FSPPPVK---------KSPGILEIQSH----PPLQRNSSFADDLELEAERDSILLPVTHVSQLRESHRAAIRVIQRMRYFVAKKRFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKITLFQTGSDRAKDKGLNTIGSRLNRMEEKITHMDKTLNCIAESLNSLLMRDSGRIGLAEAGPSLSASNSLPSYDQLSTTTFPSALEESS 654          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Cavefish
Match: kcnq1.2 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:103028784])

HSP 1 Score: 549.28 bits (1414), Expect = 0.000e+0
Identity = 319/587 (54.34%), Postives = 384/587 (65.42%), Query Frame = 2
Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRN-ASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGET-----SKEQESAPPNFI--PLPLRPAFR-----------SLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            S Q  +YNFLE P G KCFLYHF VFL+VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G +GR+RF RKPIS+IDL+V++AS VVL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D            + F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA        +TWK+Y                  +G       SE  +  +F+++++R    ++  R                    D  S  +   +  S    T      KE +   P F+  P  +   FR           +LSC A+     V+          R  ++    D         A+    +L+  H+ AI+VIRRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D ++GKP L   +   D+   TV +RL RLE + ++MD K++ IL +L
Sbjct:  141 SMQGDVYNFLERPAGLKCFLYHFLVFLMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIKGRLRFIRKPISIIDLIVVVASVVVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDEGK---------TGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYACEKPDGCPATWKMYV----------------LTGDYIPVINSENSSPGNFRKLSKRYKRRLKSTR--------------------DNGSLGNAGEKALSIPQITYDHIDDKEDKREVPFFLEEPPGITKIFRQTARHHSWSSFNLSCPASP----VKKKLDGHPDISRTNSLVDDIDFASEFIPLPAVTDASQLSHAHRSAIKVIRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHTLGKPGLFLPEKGVDKEFHTVGARLIRLEDKVLQMDQKVENILKIL 678          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Cavefish
Match: kcnq1.2 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:103028784])

HSP 1 Score: 442.195 bits (1136), Expect = 1.275e-141
Identity = 228/303 (75.25%), Postives = 253/303 (83.50%), Query Frame = 2
Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            S Q  +YNFLE P G KCFLYHF VFL+VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G +GR+RF RKPIS+IDL+V++AS VVL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D            + F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA        +TWK+Y 
Sbjct:  141 SMQGDVYNFLERPAGLKCFLYHFLVFLMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIKGRLRFIRKPISIIDLIVVVASVVVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDEGK---------TGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYACEKPDGCPATWKMYV 434          

HSP 2 Score: 136.732 bits (343), Expect = 1.231e-32
Identity = 66/106 (62.26%), Postives = 84/106 (79.25%), Query Frame = 2
Query: 1733 LTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            L+  H+ AI+VIRRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D ++GKP L   +   D+   TV +RL RLE + ++MD K++ IL +L
Sbjct:  579 LSHAHRSAIKVIRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHTLGKPGLFLPEKGVDKEFHTVGARLIRLEDKVLQMDQKVENILKIL 684          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Sea Lamprey
Match: kcnq1.1 (potassium voltage-gated channel, KQT-like subfamily, member 1.1 [Source:ZFIN;Acc:ZDB-GENE-061214-5])

HSP 1 Score: 502.671 bits (1293), Expect = 2.271e-169
Identity = 282/501 (56.29%), Postives = 328/501 (65.47%), Query Frame = 2
Query:  512 EIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKN--GQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRF-QQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQ 2005
            EI LV+FFG EY +RLWSAGCRSKY+G  GR+RFA KPIS+IDLVV++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE            DE  E + F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQ LWRC+    D +  +TW I    H +  + +        GR +       R A  K   +R    I++ +   L  P       G   G  TS  N  N    GT+S    +  Q  AP            RSL  T+T              PR               D     L     LTE HK+AIRVIRRMQ+F+A  +F QQA+KPYDVRDVIEQYSQGH+NMMVRIKELQRR+D S+GKP +   +  +DR++ T+ +RL+R+E +
Sbjct:    1 EIALVVFFGVEYLVRLWSAGCRSKYVGVMGRVRFAHKPISIIDLVVVVASIIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEK-----------DEAREKNEFASYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQSLWRCHLAESDHHSTATWMI--DAHFNGISAKTAEHVTWEGRVH-------RLAKEKEDKKRKKQLIKQAKGDGLVSP-------GARQGSSTSEGNHANTPDNGTNS---ATGWQPDAP------------RSLYHTST--------------PRSPPLLCDQPTPPTPPDLH---LHSACGLTESHKIAIRVIRRMQYFVARSKFQQQAKKPYDVRDVIEQYSQGHVNMMVRIKELQRRLDHSLGKPNMFLSEKGKDRSKYTIGARLDRVEEK 442          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001128.1 (pep scaffold:Pmarinus_7.0:GL481044:147302:155278:-1 gene:ENSPMAG00000001003.1 transcript:ENSPMAT00000001128.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 288.886 bits (738), Expect = 1.773e-90
Identity = 138/248 (55.65%), Postives = 182/248 (73.39%), Query Frame = 2
Query:  512 EIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPD-SNLHSTWKIY 1252
            E ++++ FG EY  R+W+AGC  +Y G+RGR++F+RKP  +ID++VL+AS  VL  G++G VFATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL L+FSS+ VYLAE   N+               F +YADALWWG IT+TTIGYGD  P TWVG+++A+ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQ  WR ++      +L +TW+ Y
Sbjct:   19 EYIMIVVFGIEYIARIWAAGCCCRYRGWRGRLKFSRKPFCVIDIIVLIASLAVLAAGTQGNVFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLVFSSFLVYLAEKDENQKE-------------FGTYADALWWGTITLTTIGYGDKCPVTWVGRLMAASFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRSPAAGLIQAAWRLHSTDASRPHLIATWRFY 253          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009923.1 (pep scaffold:Pmarinus_7.0:GL476399:1077789:1091635:1 gene:ENSPMAG00000008976.1 transcript:ENSPMAT00000009923.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 239.965 bits (611), Expect = 1.672e-73
Identity = 112/209 (53.59%), Postives = 154/209 (73.68%), Query Frame = 2
Query:  467 IDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPA 1093
            I ++R + ++     E ++++ FG EY +R+W+AGC  +Y G++GR+RFARKP  +ID +VL+AS  V+  G++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL L+FSS+ VYLAE   N+D              F +YADALWWG IT+TTIGYGD  PKTW+G+++A+ F++  ISFFALPA
Sbjct:    2 IKNHRSLGISCAVPQEGIMMVLFGLEYFLRIWAAGCCCRYRGWQGRLRFARKPFCIIDSIVLVASLAVIAAGTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLALVFSSFLVYLAEKDDNKDQ-------------FATYADALWWGTITLTTIGYGDKTPKTWLGRMLAAGFALLGISFFALPA 197          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009926.1 (pep scaffold:Pmarinus_7.0:GL476399:1078231:1091635:1 gene:ENSPMAG00000008976.1 transcript:ENSPMAT00000009926.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 228.794 bits (582), Expect = 2.111e-69
Identity = 110/203 (54.19%), Postives = 147/203 (72.41%), Query Frame = 2
Query:  512 EIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGV---------ITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPA 1093
            E ++++ FG EY +R+W+AGC  +Y G++GR+RFARKP  +ID +VL+AS  V+  G++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL L+FSS+ VYLAE   N+D              F +YADALWWG          IT+TTIGYGD  PKTW+G+++A+ F++  ISFFALPA
Sbjct:    6 EGIMMVLFGLEYFLRIWAAGCCCRYRGWQGRLRFARKPFCIIDSIVLVASLAVIAAGTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLALVFSSFLVYLAEKDDNKDQ-------------FATYADALWWGTGWGLLVLADITLTTIGYGDKTPKTWLGRMLAAGFALLGISFFALPA 195          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Sea Lamprey
Match: kcnq4 (potassium voltage-gated channel, KQT-like subfamily, member 4 [Source:ZFIN;Acc:ZDB-GENE-120215-132])

HSP 1 Score: 125.946 bits (315), Expect = 3.772e-34
Identity = 62/113 (54.87%), Postives = 85/113 (75.22%), Query Frame = 2
Query:  464 TIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVY 802
            TI  Y++ A   +    ++++  FG EY  R+W+AGC  +Y G+RGR RFARKP  +ID++VL+AS  V+  G++G VFATSA+R +RFLQILRM+ +DR+GGTWRLLGSVVY
Sbjct:   15 TIQTYQDAASKAVL---LLMIGVFGLEYFARIWAAGCCCRYRGWRGRCRFARKPFCVIDIIVLIASLAVIIAGTQGNVFATSALRSLRFLQILRMVRMDRRGGTWRLLGSVVY 124          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Nematostella
Match: EDO42799 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A4])

HSP 1 Score: 262.307 bits (669), Expect = 3.684e-80
Identity = 141/279 (50.54%), Postives = 192/279 (68.82%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQ 1189
            Q   YNFLE P G    +YH A+ +LV++ LIL+ LST++ Y  +    +F +EIVLV  F  EYG+RLWSAGCRS Y+G RGR+ FA+K  +++D++V+ +S   L   + G   ++  +R VRFL +LR+L  DRQG TW+LL SV+YIHR+EL+TTLY+GF+ LIF+S+ +Y+ E   N                F S+ ++ WWG++T+TTIGYGD  P TW G++ AS F+V  ISFFALPAGILGSGFALKV Q+QRQKHF+R+   AA L+Q
Sbjct:    5 QLYCYNFLERPRGLA-IVYHVALCILVIVSLILTALSTVNIYEALLDTPIFIVEIVLVTVFIVEYGLRLWSAGCRSTYVGLRGRLNFAKKTYAILDVLVIFSSIAGLALSTNG---SSITVRLVRFLPLLRVLRFDRQGSTWKLLASVIYIHRKELLTTLYLGFISLIFASFVLYMVEKDENVK--------------FDSWPNSFWWGIVTLTTIGYGDKTPITWYGRLCASIFAVCGISFFALPAGILGSGFALKVTQQQRQKHFHRRRRPAAILLQ 265          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Nematostella
Match: SHAKR7 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIU2])

HSP 1 Score: 92.8189 bits (229), Expect = 9.175e-20
Identity = 62/217 (28.57%), Postives = 99/217 (45.62%), Query Frame = 2
Query:  464 TIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGF 1114
            +I +   +A N    +E+   I+F  E   RL SA           +I+F ++P++++D++ +L   +VL    K +  + S +R  R L++LR+  + R     R+L     +   EL   +    + ++ SS   Y AE                    F+S   A WW + TVTT+GYGD  P T  GKI+ S  SVF +   ALP  +  S F
Sbjct:  179 SIGNSNVLATNVYVIIEMACYIWFTIELIFRLASAP---------EKIKFCKQPLNVVDILTVLPYYIVLAV-EKSRTGSLSVMRAARMLRVLRIFKLSRYSSGMRVLLYTFLMSLNELWMFMLFAGMSVLLSSAAAYYAETAHGRQT-------------FESIPGAFWWSISTVTTVGYGDQYPLTASGKIVGSILSVFGVLVVALPVFLFVSNF 372          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Nematostella
Match: SHAKR12 (Potassium channel; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI05])

HSP 1 Score: 89.7373 bits (221), Expect = 1.036e-18
Identity = 53/206 (25.73%), Postives = 97/206 (47.09%), Query Frame = 2
Query:  503 FWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGF-GSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVF-AISFFALPAGILGSGF 1114
            F ++  ++ +F  EY  RL SA           +++F    +++IDL+ ++   + LG    +      + +R  R L+++R+L + R     R+LG  +   + +L   +++  + +I  S  +Y  EN+ N                F S   A WW +IT+TT+GYGD  P+T  G+++ +C +VF  I    LP  +    F
Sbjct:  207 FVIDTCIITWFTSEYIARLISAP---------HKLKFVFSTLALIDLIAIIPYFISLGLDADQTHAITFTVLRIFRLLRVIRLLKLTRYVAALRILGYTIQSCQDQLTALMFLLLISIILFSSLMYYLENEENPTE-------------FYSIPAAFWWCIITMTTVGYGDTCPRTPFGRLVGACCAVFGVIVMVCLPTPVFILHF 390          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Nematostella
Match: SHAK3 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK45])

HSP 1 Score: 87.0409 bits (214), Expect = 4.500e-18
Identity = 59/226 (26.11%), Postives = 110/226 (48.67%), Query Frame = 2
Query:  464 TIDHYREVAVNTLFW-MEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQ 1138
            T DH   V  ++ +  +EI+ + +F  EY +RL S+           ++ F R  +++IDL+ +L   + L      ++ + + +R +R +++ R+  + R     ++LG  +    +EL   ++   + ++  S  VY AE             E+   S F S  DA WW V+T+TT+GYGD  P T  GK++ S  ++  +   ALP  ++ S F    +++Q
Sbjct:  177 TADHPEPVEKSSAWLALEILCIAWFTLEYVVRLLSSP---------QKLLFVRSFLNVIDLMAILPYYITLPMKDL-RITSLAVLRVIRLVRVFRIFKLSRHSRGLQVLGHTLRASSRELAMLIFFLLISVVLFSSAVYYAE-------------EEEAASKFSSIPDAFWWAVVTMTTVGYGDMYPVTPWGKLVGSICAISGVLTIALPVPVIVSNFNYFYKREQ 379          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Nematostella
Match: SHAKR9 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI03])

HSP 1 Score: 86.6557 bits (213), Expect = 5.626e-18
Identity = 55/217 (25.35%), Postives = 99/217 (45.62%), Query Frame = 2
Query:  467 IDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFG-SKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGF 1114
            +DHY     +  F +E   V +F  E+ +R+W++ C            F +    ++D+  ++   + L    S   V + + IR +R  +++R+  + R     +LL   +Y   ++L + L+   + +I  S  +Y  ++K N                  S   A WW VIT+T++GYGD VP T  GK++ S  ++  +  F LP  +L S F
Sbjct:  193 VDHY---FTDYWFVIEAYCVAWFTVEFVVRMWASPCTW---------LFVKSWFGVLDVAAIVPFYITLALKESTYGVRSFAVIRALRLFRVIRIFKLSRYSDALKLLVKTLYSSSEQLRSLLFCFLVAIILFSSIIYYVDDKDN----------------IPSIPHAFWWSVITMTSVGYGDVVPSTIAGKLVGSLCAMSGLILFCLPTPVLVSNF 381          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Medaka
Match: ENSORLT00000035260.1 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:101166715])

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 308/568 (54.23%), Postives = 379/568 (66.73%), Query Frame = 2
Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            S Q  +YNFLE P G KCFLYHF VF++VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY G +GR+RF RKPIS+IDL+V++AS +VLG GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+ +   F SYADALWWGV+TVTTIGYGD +P+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ LWRCYA    +   +TWK+Y                 ++G       +  +  + +R   R   S+       +  P            +   S   K   GT  +G     ++S PP+        +  +LSC  +   G    S S      R  +++ + D    D     +    +L+   + A++V+RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D ++GKP +       D+   T+ +++ RLE +  +MD K+D +L +L
Sbjct:  141 SMQGDVYNFLERPAGMKCFLYHFLVFIMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVLFFGTEYVVRLWSAGCRSKYAGIKGRLRFIRKPISIIDLIVVIASIIVLGVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGKTG-FSSYADALWWGVVTVTTIGYGDKIPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTLWRCYAAEKPNGCAATWKMYV-----LTPEGIAAAAADNGSPSIKKLNMAKKGTKRRPKSRGFASMGVASERAVSIPQITYDHIDDSEEKKDMSFFLKEQTGT-VEGIARMFRKSGPPHH-----SWSSFTLSCPTSPEKGSHEKSTSI--DISRANSLTDELDDMSEDIPLPVVTNKNQLSHAQRSAVKVLRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDGTLGKPGMFLPGKGEDKEYHTIGAQMIRLEEKIHQMDLKMDSVLRIL 686          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Medaka
Match: ENSORLT00000044551.1 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:101166715])

HSP 1 Score: 463.766 bits (1192), Expect = 3.148e-150
Identity = 227/303 (74.92%), Postives = 254/303 (83.83%), Query Frame = 2
Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            S Q  +YNFLE P G KCFLYHF VF++VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY G +GR+RF RKPIS+IDL+V++AS +VLG GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+ +   F SYADALWWGV+TVTTIGYGD +P+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ LWRCYA    +   +TWK+Y 
Sbjct:  141 SMQGDVYNFLERPAGMKCFLYHFLVFIMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVLFFGTEYVVRLWSAGCRSKYAGIKGRLRFIRKPISIIDLIVVIASIIVLGVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGKTG-FSSYADALWWGVVTVTTIGYGDKIPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTLWRCYAAEKPNGCAATWKMYV 434          

HSP 2 Score: 129.413 bits (324), Expect = 2.523e-30
Identity = 62/132 (46.97%), Postives = 90/132 (68.18%), Query Frame = 2
Query: 1655 RKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            R  +++ + D    D     +    +L+   + A++V+RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D ++GKP +       D+   T+ +++ RLE +  +MD K+D +L +L
Sbjct:  528 RANSLTDELDDMSEDIPLPVVTNKNQLSHAQRSAVKVLRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDGTLGKPGMFLPGKGEDKEYHTIGAQMIRLEEKIHQMDLKMDSVLRIL 659          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Medaka
Match: ENSORLT00000003018.2 (potassium voltage-gated channel subfamily KQT member 1-like [Source:NCBI gene;Acc:101166715])

HSP 1 Score: 456.447 bits (1173), Expect = 1.407e-147
Identity = 227/302 (75.17%), Postives = 254/302 (84.11%), Query Frame = 2
Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            S Q  +YNFLE P G KCFLYHF VF++VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY G +GR+RF RKPIS+IDL+V++AS +VLG GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+ +   F SYADALWWGV+TVTTIGYGD +P+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ LWRCYA    +   +TWK+Y
Sbjct:  141 SMQGDVYNFLERPAGMKCFLYHFLVFIMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVLFFGTEYVVRLWSAGCRSKYAGIKGRLRFIRKPISIIDLIVVIASIIVLGVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGKTG-FSSYADALWWGVVTVTTIGYGDKIPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTLWRCYAAEKPNGCAATWKMY 433          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Medaka
Match: kcnq1.1 (potassium voltage-gated channel subfamily KQT member 1 [Source:NCBI gene;Acc:101161541])

HSP 1 Score: 448.358 bits (1152), Expect = 1.774e-144
Identity = 221/287 (77.00%), Postives = 248/287 (86.41%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV 1213
            Q  +YNFLE PTGW+CF+YHF VFL+VL CLILSVLSTID ++ +A  TLFW+EIVLV+FFG EY IRLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GSKGQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIFSSYFVYLAE  +          + S  + F +YADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+AV
Sbjct:  100 QGRVYNFLERPTGWRCFVYHFTVFLIVLACLILSVLSTIDQFQALAHTTLFWVEIVLVVFFGVEYFIRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASIIVLSVGSKGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLSLIFSSYFVYLAEKDAV---------DSSGATEFGNYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTAWRCFAV 377          

HSP 2 Score: 136.346 bits (342), Expect = 1.418e-32
Identity = 81/184 (44.02%), Postives = 110/184 (59.78%), Query Frame = 2
Query: 1523 KEQESAPPNFIPLPLRPAF---RSLSCTATSGIGYVR-----ASFSAVRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            K+   A P    +   P F   R LS    S +G V+         ++ P RR  + +   + E E D+E +       LTE H+ AIRV++RM++F+A+R+FQQARKPYDVRDVIEQYSQGH+N+MVRIKELQRR+DQS+GK   F       RD+   ++ SRLNR+E +   MD  L  I+
Sbjct:  420 KDNGPASPTMPGVTHDPVFDSGRELSSDVYSSVGTVKRNAGILDVHSMTPIRRNCSFADDLELESERDTELSPASSISHLTESHRKAIRVVQRMRYFVAKRKFQQARKPYDVRDVIEQYSQGHVNLMVRIKELQRRLDQSLGKMTLFQTGTDRARDKGNNSIGSRLNRMEDKISHMDQTLTLIM 603          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Medaka
Match: kcnq1.1 (potassium voltage-gated channel subfamily KQT member 1 [Source:NCBI gene;Acc:101161541])

HSP 1 Score: 447.588 bits (1150), Expect = 5.784e-144
Identity = 221/287 (77.00%), Postives = 248/287 (86.41%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV 1213
            Q  +YNFLE PTGW+CF+YHF VFL+VL CLILSVLSTID ++ +A  TLFW+EIVLV+FFG EY IRLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GSKGQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIFSSYFVYLAE  +          + S  + F +YADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+AV
Sbjct:  100 QGRVYNFLERPTGWRCFVYHFTVFLIVLACLILSVLSTIDQFQALAHTTLFWVEIVLVVFFGVEYFIRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASIIVLSVGSKGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLSLIFSSYFVYLAEKDAV---------DSSGATEFGNYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTAWRCFAV 377          

HSP 2 Score: 133.265 bits (334), Expect = 1.434e-31
Identity = 70/133 (52.63%), Postives = 92/133 (69.17%), Query Frame = 2
Query: 1658 KRTISHQEDTE---ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            +R  S  +D E   E D+E +       LTE H+ AIRV++RM++F+A+R+FQQARKPYDVRDVIEQYSQGH+N+MVRIKELQRR+DQS+GK   F       RD+   ++ SRLNR+E +   MD  L  I+
Sbjct:  490 RRNCSFADDLELESERDTELSPASSISHLTESHRKAIRVVQRMRYFVAKRKFQQARKPYDVRDVIEQYSQGHVNLMVRIKELQRRLDQSLGKMTLFQTGTDRARDKGNNSIGSRLNRMEDKISHMDQTLTLIM 622          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Planmine SMEST
Match: SMESG000022978.1 (SMESG000022978.1)

HSP 1 Score: 1746.1 bits (4521), Expect = 0.000e+0
Identity = 916/918 (99.78%), Postives = 916/918 (99.78%), Query Frame = 2
Query:   95 MALRYNSDNHIINIHDEKIEVRIIDNETSQIVYDKLENDEDRDEDYLLTKRKSELEKRRQSRMITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQTLLHPTCSGKLLRSSSFSTSQIPQISEKEKTSNVNSFLKQKVFRSQSTKVSKKTHLSPDSKFDRKDSMKHPHFTKNLSVEETEQTVSPGEKPQICECSSYAQFTTNINQCSASFIPAXXXXXXXXXXMYTPSPEFLSSPEFCDMREPQRVMSAINIXXXXXXXXXXXXXXXQTTMTTELIQTDNQEKIILNVPNINMEADISDILRRRNTPSFVFP 2848
            MA RYNSDNHIINIHDEKIEVRIIDNETSQIVYDKLENDEDRDEDYLLTKRKSELEKRRQSRMITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFLLVLICLILSVLSTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTQLHSHCHNPQHHHQNGNSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFSNNSSNGGGAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT LHPTCSGKLLRSSSFSTSQIPQISEKEKTSNVNSFLKQKVFRSQSTKVSKKTHLSPDSKFDRKDSMKHPHFTKNLSVEETEQTVSPGEKPQICECSSYAQFTTNINQCSASFIPALSSPPSLNSSMYTPSPEFLSSPEFCDMREPQRVMSAINISAPVTPPPPVSTYAYQTTMTTELIQTDNQEKIILNVPNINMEADISDILRRRNTPSFVFP
Sbjct:    1 MASRYNSDNHIINIHDEKIEVRIIDNETSQIVYDKLENDEDRDEDYLLTKRKSELEKRRQSRMITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFLLVLICLILSVLSTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTQLHSHCHNPQHHHQNGNSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFSNNSSNGGGAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT-LHPTCSGKLLRSSSFSTSQIPQISEKEKTSNVNSFLKQKVFRSQSTKVSKKTHLSPDSKFDRKDSMKHPHFTKNLSVEETEQTVSPGEKPQICECSSYAQFTTNINQCSASFIPALSSPPSLNSSMYTPSPEFLSSPEFCDMREPQRVMSAINISAPVTPPPPVSTYAYQTTMTTELIQTDNQEKIILNVPNINMEADISDILRRRNTPSFVFP 917          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Planmine SMEST
Match: SMESG000040474.1 (SMESG000040474.1)

HSP 1 Score: 466.077 bits (1198), Expect = 1.510e-153
Identity = 231/301 (76.74%), Postives = 259/301 (86.05%), Query Frame = 2
Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            +T IYNFLE PTGWKCFLYHF VF++VL+CLI SV+STID Y E++   L+ ME +LV FFG EY IRLWS+GCRSKY+GF GR+RF RKPIS+IDL+V++AS +VL FGSKG+VFATSAIRG+RF+QILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGL+FSSYFVYL+EN SNE +N            F SYADALWWGV+TVTTIGYGD VPKTW+GKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQCLWR +A S   N  +TW+IYT
Sbjct:   51 KTKIYNFLERPTGWKCFLYHFTVFIMVLVCLIFSVISTIDVYYEMSSYLLYIMETILVFFFGAEYIIRLWSSGCRSKYLGFSGRLRFMRKPISLIDLIVVVASFIVLLFGSKGKVFATSAIRGIRFMQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLVFSSYFVYLSEN-SNEPSNE-----------FMSYADALWWGVVTVTTIGYGDKVPKTWIGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAANLIQCLWRLHASSVKFNSVATWRIYT 339          

HSP 2 Score: 129.413 bits (324), Expect = 5.187e-31
Identity = 67/138 (48.55%), Postives = 94/138 (68.12%), Query Frame = 2
Query: 1628 SFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            S+   RP  RK    H   T+E +      R+P+ L    K+AIRV+RRM++++A R+FQQ RKPYDV+DVIEQYSQGHLNMMVR+KELQRR+DQ++GKP   + ++  DR R+T+  RL  +E +   ++SK+   L
Sbjct:  356 SYPHTRPNTRKNL--HDLFTKEKNE---IRREPINLNSSQKVAIRVLRRMRYYVARRKFQQTRKPYDVKDVIEQYSQGHLNMMVRLKELQRRLDQTLGKP---AHRNNIDRHRMTIAQRLLVIEYKITDLESKVAETL 485          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Planmine SMEST
Match: SMESG000028167.1 (SMESG000028167.1)

HSP 1 Score: 457.988 bits (1177), Expect = 2.009e-151
Identity = 245/384 (63.80%), Postives = 287/384 (74.74%), Query Frame = 2
Query:  107 YNSDNHIINIHDEKIEVRIIDNETSQIVYDKLENDEDRDEDYLLTKRKSELEKRRQSRMITNAVRLDLQR-SILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            + S   +IN H++ + + + DNE          N  D   +  + KR S L  +            D Q+ SI        S QT +YNFLE PTGWKCFLYHF VFL+VLICLILSVLST+++Y E+A+  LF ME++L+IFF  E+ IRLWSAGCRSK++G  GR++F +KPIS+IDLVV++AS  VL  G+KGQVFATSAIRG+RFLQILRMLHVDRQG TWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFV+LAEN + +             + F SYAD+LWWGV+TVTTIGYGD VPKTW+GKI+ASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQCLWR YA S   N  +TWKIYT
Sbjct:   50 FQSMPGLINSHNDSLTIDL-DNE----------NGSDLKVNEKVRKRLSSLFGK------------DWQKISIFTSYRAKLSFQTKVYNFLERPTGWKCFLYHFTVFLMVLICLILSVLSTVEYYSEMAIELLFIMEMILLIFFTTEFSIRLWSAGCRSKFLGLSGRLKFIKKPISIIDLVVIIASMTVLIAGTKGQVFATSAIRGIRFLQILRMLHVDRQGSTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVFLAENATEQS------------AEFISYADSLWWGVVTVTTIGYGDKVPKTWIGKIVASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQCLWRLYASSNKKNSEATWKIYT 398          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Planmine SMEST
Match: SMESG000040474.1 (SMESG000040474.1)

HSP 1 Score: 416.772 bits (1070), Expect = 6.041e-135
Identity = 196/249 (78.71%), Postives = 217/249 (87.15%), Query Frame = 2
Query:  509 MEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            +E +LV FFG EY IRLWS+GCRSKY+GF GR+RF RKPIS+IDL+V++AS +VL FGSKG+VFATSAIRG+RF+QILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGL+FSSYFVYL+EN SNE +N            F SYADALWWGV+TVTTIGYGD VPKTW+GKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQCLWR +A S   N  +TW+IYT
Sbjct:   71 LETILVFFFGAEYIIRLWSSGCRSKYLGFSGRLRFMRKPISLIDLIVVVASFIVLLFGSKGKVFATSAIRGIRFMQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLVFSSYFVYLSEN-SNEPSNE-----------FMSYADALWWGVVTVTTIGYGDKVPKTWIGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAANLIQCLWRLHASSVKFNSVATWRIYT 307          

HSP 2 Score: 129.798 bits (325), Expect = 2.908e-31
Identity = 67/138 (48.55%), Postives = 94/138 (68.12%), Query Frame = 2
Query: 1628 SFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            S+   RP  RK    H   T+E +      R+P+ L    K+AIRV+RRM++++A R+FQQ RKPYDV+DVIEQYSQGHLNMMVR+KELQRR+DQ++GKP   + ++  DR R+T+  RL  +E +   ++SK+   L
Sbjct:  324 SYPHTRPNTRKNL--HDLFTKEKNE---IRREPINLNSSQKVAIRVLRRMRYYVARRKFQQTRKPYDVKDVIEQYSQGHLNMMVRLKELQRRLDQTLGKP---AHRNNIDRHRMTIAQRLLVIEYKITDLESKVAETL 453          
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Planmine SMEST
Match: SMESG000046611.1 (SMESG000046611.1)

HSP 1 Score: 403.675 bits (1036), Expect = 4.391e-125
Identity = 257/607 (42.34%), Postives = 363/607 (59.80%), Query Frame = 2
Query:  248 KSELEKRRQSRMITNAVRLDLQRSILN---HMNNTQSR--QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKE--QESAPPNFI--PLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            KS   K R SR      R  L    LN   + N+ + R  Q  IYNFLE P  +   +YH  +F  V +CL+LSVLSTI  Y  +A   L + E+V++ +F  EY +R+WSAGCRS+Y  +RGRI+FA++P  ++D+VV+LAS VVL  GS  Q  A SA RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFLGLIFSS+ +YL E   N+  N              +YADALWWGVIT+ T+GYGD VP+TW+GKIIA+  +V  ISFFALPAGILGSGFALKVQQ QRQKH  R+   AATLIQCLWRCYA  P+S   +TWKI+              ++  +  R + F    R +S KR  RR   SI    PS         SS       +TS  N        ++   S +   E    N I     ++  FR+L+ +  S +    +S  A R R     ++ ++++  +D     ++   +LTE  K  IR +R+++FF+A ++F++A +PYDV+DV+EQYS GH++M+ RIK LQ R+D  +G+   +  Q+    T++++ +R+ ++E Q   +++KLD ++
Sbjct:   48 KSSYFKERHSRH-----RTSLHGKALNFRANRNDARYRRLQAKIYNFLERPKTYSSIIYHILIFASVFMCLMLSVLSTIAKYDHIAGEALLYTELVMLFWFFTEYCLRMWSAGCRSRYQSWRGRIQFAKRPFCLVDVVVILASVVVLVIGSDRQKIAASAFRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTVYIGFLGLIFSSFLIYLVEKDKNQKIN--------------TYADALWWGVITLCTVGYGDIVPETWIGKIIAAFCAVAGISFFALPAGILGSGFALKVQQHQRQKHLIRRRVPAATLIQCLWRCYAADPNSTSGATWKIH----------MKPLRSPPNSDRLTRF---GRFSSIKR--RREKGSILHSHPSN--------SSLYRRNAIETSVPNQVTPSCEENEFPASNDVYNEEFLENSINSSRSMKKRFRALAQSMKSHMNINPSSIEASR-RSSNFVMAIEKESAVNDE----IQFITQLTEADKNVIRAVRKIKFFVARKKFREALRPYDVKDVMEQYSAGHVDMLARIKNLQSRLDLIVGQHGSKDNQNY--ETKISLTTRIIKIEKQVESIETKLDLLI 605          
The following BLAST results are available for this feature:
BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNQ11.554e-15174.61potassium voltage-gated channel subfamily Q member... [more]
KCNQ12.905e-13878.03potassium voltage-gated channel subfamily Q member... [more]
KCNQ41.211e-12541.64potassium voltage-gated channel subfamily Q member... [more]
KCNQ55.566e-12541.31potassium voltage-gated channel subfamily Q member... [more]
KCNQ57.444e-12541.48potassium voltage-gated channel subfamily Q member... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kqt-34.801e-13971.00Potassium channel, KvQLT family [Source:UniProtKB... [more]
kqt-34.801e-13971.00Potassium channel, KvQLT family [Source:UniProtKB... [more]
kqt-31.454e-13871.00Potassium channel, KvQLT family [Source:UniProtKB... [more]
kqt-31.454e-13871.00Potassium channel, KvQLT family [Source:UniProtKB... [more]
kqt-31.556e-13871.00Potassium channel, KvQLT family [Source:UniProtKB... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KCNQ1.924e-11160.00gene:FBgn0033494 transcript:FBtr0299832[more]
KCNQ4.619e-11160.00gene:FBgn0033494 transcript:FBtr0299833[more]
KCNQ1.074e-11060.00gene:FBgn0033494 transcript:FBtr0310097[more]
KCNQ1.394e-11060.00gene:FBgn0033494 transcript:FBtr0310093[more]
KCNQ1.400e-11060.00gene:FBgn0033494 transcript:FBtr0310094[more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnq1.17.895e-15472.92potassium voltage-gated channel, KQT-like subfamil... [more]
kcnq1.18.886e-15472.92potassium voltage-gated channel, KQT-like subfamil... [more]
kcnq1.15.140e-15273.15potassium voltage-gated channel, KQT-like subfamil... [more]
kcnq1.23.784e-14074.92potassium voltage-gated channel, KQT-like subfamil... [more]
kcnq2b1.563e-10156.48potassium voltage-gated channel, KQT-like subfamil... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000046823.18.323e-15677.27potassium voltage-gated channel subfamily KQT memb... [more]
ENSXETT00000046791.12.021e-15577.27potassium voltage-gated channel subfamily KQT memb... [more]
ENSXETT00000046831.18.280e-15576.62potassium voltage-gated channel subfamily KQT memb... [more]
ENSXETT00000046772.11.126e-15477.27potassium voltage-gated channel subfamily KQT memb... [more]
kri11.602e-15167.96KRI1 homolog [Source:Xenbase;Acc:XB-GENE-6036517][more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kcnq15.120e-15273.77potassium voltage-gated channel, subfamily Q, memb... [more]
Kcnq11.918e-15173.77potassium voltage-gated channel, subfamily Q, memb... [more]
Kcnq53.721e-12442.86potassium voltage-gated channel, subfamily Q, memb... [more]
Kcnq56.452e-12442.49potassium voltage-gated channel, subfamily Q, memb... [more]
Kcnq24.883e-12341.70potassium voltage-gated channel, subfamily Q, memb... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O70344|KCNQ1_CAVPO7.470e-15274.38Potassium voltage-gated channel subfamily KQT memb... [more]
sp|P70057|KCNQ1_XENLA2.431e-15170.06Potassium voltage-gated channel subfamily KQT memb... [more]
sp|P97414|KCNQ1_MOUSE3.581e-15173.77Potassium voltage-gated channel subfamily KQT memb... [more]
sp|O97531|KCNQ1_FELCA4.789e-15177.93Potassium voltage-gated channel subfamily KQT memb... [more]
sp|P51787|KCNQ1_HUMAN7.465e-15174.61Potassium voltage-gated channel subfamily KQT memb... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
X1YV700.000e+060.35Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A2S1WM530.000e+057.57Putative potassium voltage-gated channel subfamily... [more]
A0A433SVX00.000e+058.81Uncharacterized protein (Fragment) OS=Elysia chlor... [more]
A0A210QEF20.000e+056.08Potassium voltage-gated channel subfamily KQT memb... [more]
A0A2T7P7710.000e+056.91Uncharacterized protein OS=Pomacea canaliculata OX... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnq1.10.000e+052.03potassium voltage-gated channel subfamily Q member... [more]
kcnq1.10.000e+052.03potassium voltage-gated channel subfamily Q member... [more]
kcnq1.10.000e+052.27potassium voltage-gated channel subfamily Q member... [more]
kcnq1.20.000e+054.34potassium voltage-gated channel subfamily KQT memb... [more]
kcnq1.21.275e-14175.25potassium voltage-gated channel subfamily KQT memb... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kcnq1.12.271e-16956.29potassium voltage-gated channel, KQT-like subfamil... [more]
ENSPMAT00000001128.11.773e-9055.65pep scaffold:Pmarinus_7.0:GL481044:147302:155278:-... [more]
ENSPMAT00000009923.11.672e-7353.59pep scaffold:Pmarinus_7.0:GL476399:1077789:1091635... [more]
ENSPMAT00000009926.12.111e-6954.19pep scaffold:Pmarinus_7.0:GL476399:1078231:1091635... [more]
kcnq43.772e-3454.87potassium voltage-gated channel, KQT-like subfamil... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO427993.684e-8050.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
SHAKR79.175e-2028.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
SHAKR121.036e-1825.73Potassium channel; Predicted protein [Source:UniP... [more]
SHAK34.500e-1826.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
SHAKR95.626e-1825.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000035260.10.000e+054.23potassium voltage-gated channel subfamily KQT memb... [more]
ENSORLT00000044551.13.148e-15074.92potassium voltage-gated channel subfamily KQT memb... [more]
ENSORLT00000003018.21.407e-14775.17potassium voltage-gated channel subfamily KQT memb... [more]
kcnq1.11.774e-14477.00potassium voltage-gated channel subfamily KQT memb... [more]
kcnq1.15.784e-14477.00potassium voltage-gated channel subfamily KQT memb... [more]
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BLAST of Potassium voltage-gated channel subfamily KQT member 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000022978.10.000e+099.78SMESG000022978.1[more]
SMESG000040474.11.510e-15376.74SMESG000040474.1[more]
SMESG000028167.12.009e-15163.80SMESG000028167.1[more]
SMESG000040474.16.041e-13578.71SMESG000040474.1[more]
SMESG000046611.14.391e-12542.34SMESG000046611.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033794 ID=SMED30033794|Name=Potassium voltage-gated channel subfamily KQT member 1|organism=Schmidtea mediterranea sexual|type=transcript|length=3099bp
ATGATTTTCTGTGATTTTTGAAAAGATGATTTTGATTGAAATTGCAATCT
TTTTTTGGTTCTTTTTTAAATCATAATCACCAAATTCATTTCTAATGGCT
TTGAGATACAATTCTGACAATCACATTATCAATATACACGATGAGAAAAT
CGAAGTGAGAATCATCGACAACGAAACCAGTCAAATAGTTTATGACAAAT
TGGAAAACGATGAAGACCGAGACGAGGATTATTTGCTTACGAAACGAAAA
TCGGAACTGGAAAAGCGACGTCAGTCAAGAATGATTACGAACGCTGTGAG
ATTGGATCTCCAGCGATCGATTTTGAATCACATGAACAACACTCAGAGTC
GACAAACGATAATTTATAATTTTCTAGAATTTCCCACCGGTTGGAAATGC
TTCCTATACCATTTTGCTGTATTCCTATTGGTTTTGATCTGCTTAATTCT
AAGCGTTTTATCAACAATTGACCATTATAGAGAGGTTGCGGTGAACACAT
TGTTTTGGATGGAAATAGTTTTAGTAATATTCTTTGGTTGTGAATATGGA
ATTCGGCTGTGGTCTGCAGGTTGTCGAAGCAAATATATGGGTTTCAGAGG
CAGGATAAGGTTTGCCCGAAAACCAATTTCAATGATAGATTTAGTAGTCT
TACTAGCATCATGTGTCGTCTTAGGATTTGGTTCAAAAGGACAAGTATTT
GCTACCTCTGCAATACGTGGAGTTAGATTTCTTCAAATTCTTCGAATGTT
GCACGTTGACAGACAAGGTGGGACATGGAGACTTCTTGGATCGGTGGTTT
ACATTCATCGGCAGGAGCTCATAACAACTCTTTACATTGGATTTTTGGGA
CTTATATTTTCATCTTATTTTGTTTATCTTGCCGAGAATAAGTCCAATGA
AGATAACAACAACTTAAAATCAGATGAGGATTCAGAAATTTCATATTTCA
AAAGCTATGCAGACGCTCTTTGGTGGGGTGTAATTACAGTTACGACTATT
GGATACGGTGATGCAGTTCCAAAAACATGGGTAGGCAAGATAATTGCTTC
CTGTTTTTCAGTTTTTGCTATCTCGTTTTTTGCTTTACCTGCCGGAATTC
TCGGTTCCGGGTTCGCTTTGAAGGTTCAACAAAAGCAAAGGCAAAAGCAT
TTTAATCGACAAATTCCTGCTGCCGCCACTTTGATTCAATGCTTATGGCG
TTGTTATGCTGTTTCTCCAGACAGCAACTTGCATTCAACTTGGAAAATTT
ACACTCAACTCCATTCCCATTGCCACAATCCGCAACATCATCATCAAAAT
GGTAACAGTGGTCGAAGATATTCTCACTTCTTTTCCGAAATGCGTAATGC
CAGTTTTAAACGAATGGCCAGGCGCGCAAGCAATTCAATTAGGCGACAAA
GACCGTCGACATTGTTCTTTCCATTTTCAAACAACTCAAGTAATGGTGGT
GGAGCGGGTCAAGATACCTCCAGTAATAATGATAAAAATGGACAAGGAAC
CTCGTCACAAGGTGAAACAAGCAAAGAACAAGAATCAGCGCCACCCAATT
TTATTCCATTACCACTGAGACCCGCTTTTCGATCACTGAGTTGTACAGCA
ACAAGTGGAATTGGTTATGTTAGAGCTTCGTTTTCGGCCGTCAGGCCTAG
ACGAAGAAAAAGAACTATTTCTCATCAGGAAGATACCGAAGAATCAGACA
GTGAATGTACAGCTCTCAGGAAGCCATTGGAACTGACAGAAGACCATAAA
TTGGCCATTAGAGTCATTAGACGGATGCAATTCTTTCTAGCAGAAAGGCG
ATTTCAACAAGCTCGTAAGCCTTATGATGTTAGAGATGTCATTGAACAGT
ACTCTCAAGGTCATTTGAATATGATGGTCAGGATCAAGGAACTACAGAGA
AGAATGGACCAATCCATCGGGAAACCATTTTTGAGATCATGTCAAGATAA
AAGAGATCGAACAAGACTAACAGTTCTTTCCAGGCTCAATAGATTAGAAA
GTCAGTCCATAAAAATGGATTCTAAGTTAGACAGAATTCTACTGTTGTTA
TCACGAATAGCTTCCTGTTCTATAAATAACCAAAGATCGTCTCACTTTCG
ATCGGATGCCTGTCCAACTCATTCGGTTTACAATTCTTCAACTGGCCCAG
TTGTCTATCAAAAATCCAGCCAACCGTCAGAAAATCAAACACAATGTCAA
ACACTTCTTCACCCGACTTGCTCAGGGAAACTTCTACGTTCCAGCAGTTT
TTCAACATCTCAAATACCTCAAATTTCAGAAAAAGAAAAAACCAGTAACG
TAAACAGTTTTTTAAAACAAAAAGTATTTCGATCTCAATCAACAAAAGTT
TCAAAGAAAACTCATCTTTCTCCAGATTCAAAATTCGACAGAAAAGATTC
CATGAAACATCCACATTTTACGAAAAATCTTAGTGTTGAAGAAACTGAGC
AGACTGTTTCTCCTGGTGAGAAACCACAGATTTGTGAATGCTCAAGTTAT
GCTCAGTTTACGACCAATATCAATCAGTGTAGCGCATCATTCATACCAGC
ATTGAGTTCACCTCCTTCGCTCAATTCCTCCATGTACACTCCTAGTCCGG
AATTTTTGTCGAGTCCTGAATTCTGTGACATGAGAGAACCACAAAGAGTA
ATGAGTGCAATAAATATTTCTGCTCCAGTAACTCCGCCACCTCCAGTTTC
AACATATGCTTATCAGACAACCATGACGACTGAATTAATCCAAACAGACA
ATCAAGAAAAAATAATTCTCAATGTTCCAAACATCAACATGGAGGCTGAT
ATATCTGATATTTTAAGACGTCGGAACACTCCTTCTTTTGTTTTTCCGTG
ATGAGCCTCCAAGTGTTTGGTAGATTGAATTTTTGTAAAAGTTTTTTTTA
TATGCATATCTGAAGAACAATTGAAGGAAAGTTCTTTGATATATACCACG
CTCATCAGAACTTTATCAAACTTCAAATTGGATTTTTTTAATTTTGAAAA
CGACAATTAAAACAAATGTTGTGCTGCTATTGATTGAATATTGAATTTTC
TGTTTCTTATTGACTTTATTAATTATTTTTAGAAAATATAAACAACTAT
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protein sequence of SMED30033794-orf-1

>SMED30033794-orf-1 ID=SMED30033794-orf-1|Name=SMED30033794-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=919bp
MALRYNSDNHIINIHDEKIEVRIIDNETSQIVYDKLENDEDRDEDYLLTK
RKSELEKRRQSRMITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGW
KCFLYHFAVFLLVLICLILSVLSTIDHYREVAVNTLFWMEIVLVIFFGCE
YGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQ
VFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGF
LGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVT
TIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQ
KHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTQLHSHCHNPQHHH
QNGNSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFSNNSSN
GGGAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSC
TATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTED
HKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKEL
QRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILL
LLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQ
CQTLLHPTCSGKLLRSSSFSTSQIPQISEKEKTSNVNSFLKQKVFRSQST
KVSKKTHLSPDSKFDRKDSMKHPHFTKNLSVEETEQTVSPGEKPQICECS
SYAQFTTNINQCSASFIPALSSPPSLNSSMYTPSPEFLSSPEFCDMREPQ
RVMSAINISAPVTPPPPVSTYAYQTTMTTELIQTDNQEKIILNVPNINME
ADISDILRRRNTPSFVFP*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0005244voltage-gated ion channel activity
GO:0005251delayed rectifier potassium channel activity
GO:0005516calmodulin binding
GO:0005546phosphatidylinositol-4,5-bisphosphate binding
GO:0008157protein phosphatase 1 binding
GO:0015271outward rectifier potassium channel activity
GO:0034236protein kinase A catalytic subunit binding
GO:0034237protein kinase A regulatory subunit binding
GO:0044325ion channel binding
GO:0086008voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
GO:0086089voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
GO:0097110scaffold protein binding
GO:1902282voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO:0005249voltage-gated potassium channel activity
GO:0005216ion channel activity
GO:0005267potassium channel activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005764lysosome
GO:0005768endosome
GO:0005769early endosome
GO:0005770late endosome
GO:0005783endoplasmic reticulum
GO:0005886plasma membrane
GO:0016323basolateral plasma membrane
GO:0030659cytoplasmic vesicle membrane
GO:0031410cytoplasmic vesicle
GO:0034702ion channel complex
GO:0045121membrane raft
GO:0016020membrane
GO:0008076voltage-gated potassium channel complex
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006349regulation of gene expression by genetic imprinting
GO:0010460positive regulation of heart rate
GO:0016458gene silencing
GO:0034765regulation of ion transmembrane transport
GO:0035690cellular response to drug
GO:0048839inner ear development
GO:0050892intestinal absorption
GO:0060048cardiac muscle contraction
GO:0060306regulation of membrane repolarization
GO:0060307regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060372regulation of atrial cardiac muscle cell membrane repolarization
GO:0060452positive regulation of cardiac muscle contraction
GO:0060453regulation of gastric acid secretion
GO:0070293renal absorption
GO:0071320cellular response to cAMP
GO:0072358cardiovascular system development
GO:0086005ventricular cardiac muscle cell action potential
GO:0086009membrane repolarization
GO:0086011membrane repolarization during action potential
GO:0086013membrane repolarization during cardiac muscle cell action potential
GO:0086014atrial cardiac muscle cell action potential
GO:0086091regulation of heart rate by cardiac conduction
GO:0097623potassium ion export across plasma membrane
GO:0098914membrane repolarization during atrial cardiac muscle cell action potential
GO:0098915membrane repolarization during ventricular cardiac muscle cell action potential
GO:1901381positive regulation of potassium ion transmembrane transport
GO:0006813potassium ion transport
GO:0006811ion transport
GO:0055085transmembrane transport
GO:0006810transport
GO:0071805potassium ion transmembrane transport
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR003937K_chnl_volt-dep_KCNQ
IPR028325VG_K_chnl
IPR005827K_chnl_volt-dep_KCQN1
IPR013821K_chnl_volt-dep_KCNQ_C
IPR005821Ion_trans_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003937Potassium channel, voltage dependent, KCNQPRINTSPR01459KCNQCHANNELcoord: 146..165
score: 57.26
coord: 228..247
score: 71.94
coord: 166..185
score: 62.1
IPR005827Potassium channel, voltage dependent, KCNQ1PRINTSPR01460KCNQ1CHANNELcoord: 635..655
score: 25.17
coord: 549..566
score: 58.73
coord: 615..634
score: 35.0
NoneNo IPR availablePRINTSPR00169KCHANNELcoord: 285..307
score: 53.34
coord: 138..161
score: 25.99
coord: 314..340
score: 30.7
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 103..343
e-value: 2.4E-53
score: 182.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 431..482
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 424..483
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 755..771
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 746..771
NoneNo IPR availablePANTHERPTHR11537:SF259KCNQ POTASSIUM CHANNEL, ISOFORM Fcoord: 82..707
NoneNo IPR availableSUPERFAMILYSSF81324Voltage-gated potassium channelscoord: 97..341
NoneNo IPR availableTMHMMTMhelixcoord: 178..197
NoneNo IPR availableTMHMMTMhelixcoord: 135..157
NoneNo IPR availableTMHMMTMhelixcoord: 103..125
NoneNo IPR availableTMHMMTMhelixcoord: 243..262
NoneNo IPR availableTMHMMTMhelixcoord: 320..342
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 105..343
e-value: 9.7E-25
score: 87.2
IPR013821Potassium channel, voltage dependent, KCNQ, C-terminalPFAMPF03520KCNQ_channelcoord: 526..650
e-value: 2.2E-25
score: 89.6
IPR028325Voltage-gated potassium channelPANTHERPTHR11537VOLTAGE-GATED POTASSIUM CHANNELcoord: 82..707