Potassium voltage-gated channel subfamily KQT member 1

Query:  296 VRLDLQRSILNHMNNTQSR---QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            V LD + SI +      +R   Q  +YNFLE PTGWKCF+YHFAVFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   STWKIY
Sbjct:   85 VSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---STWKIY 395          

Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  481 RTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLS 618          

Query:  464 TIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            TI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   STWKIY
Sbjct:   17 TIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---STWKIY 268          

Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  354 RTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLS 491          

Query:  311 QRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPD-SNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMA-RRASNSIRRQRP-STLFFPFXXXXXXXXXAGQDTSSN-NDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYV-------RASFSA---VRPRRRKRTISHQEDTEESDSECTALRKPLELTEDH-----KLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGK-PFLRSCQDKRDRT--------RLTVLSRLNRLESQSIKMDSKLDRILLLLSR 2056
            QRS   H    +  Q  +YN LE P GW  F+YH  +FLLV  CL+LSVLSTI  ++E+A   L  +E V+++ FG EY +R+WSAGC  +Y G++GR RFARKP  +ID +V +AS  V+  G++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIF+S+ VYLAE  +N D              F SYAD+LWWG IT+TTIGYGD  P TW+G+++A+ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQ  WR Y+     + L +TW  Y  +           ++    R       E+R A     A  R        RP ST F P           G+ +     D+   G+S +     +Q  APP    +P  P+   +   ATS            R  F A   ++PR        +E  EE   +C       ELT D      K  IR IR ++F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +G+ P  R  ++K D+          ++++ R+ ++E Q   ++ KLD +L   SR
Sbjct:   71 QRSSAAH-KRYRRLQNWVYNVLERPRGW-AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSD--------------FSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCP-----------GESSRMGIKDRIRMGSSQRRTGPSKQHLAPPT---MPTSPSSEQVG-EATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQC-------ELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSR 642          

Query:  269 RQSRMITNAVRLDLQRSILNHMNNTQSR--------QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDT-EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLT----------VLSRLNRLESQSIKMDSKLDRIL 2041
            R+SR      R+ L    L++ ++   R        Q  +YN LE P GW  F+YH  VFL V  CLILSV STI  + ++A + L  +E V+++ FG E+ IR+WSAGC  +Y G++GR+RFARKP  +ID +VL+AS  V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIFSS+ VYL E  +N++              F +YADALWWG IT+TTIGYGD  P TW+G+++++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQC+WR YA    S   +TWK + +    C   +      +S ++ S  F E       RMA     SI+ ++ S                G   S + D      +++G  +K Q+S   N      R  FR            +R   S  +P     T    +D  +E   +C    +  +LT   K  IR IR M+F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +GK  + S  DK+ R ++T          +L R+ ++E Q   ++SKLD +L
Sbjct:   76 RESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGW-AFIYHAFVFLPVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKE--------------FSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSQKLS--FKER-----VRMASPRGQSIKSRQASV---------------GDRRSPSTD-----ITAEGSPTKVQKSWSFND-----RTRFRP----------SLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVE--DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITS--DKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLL 624          

Query:  269 RQSRMITNAVRLDLQRSILNHMNNTQSR--------QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDT-EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLT----------VLSRLNRLESQSIKMDSKLDRIL 2041
            R+SR      R+ L    L++ ++   R        Q  +YN LE P GW  F+YH  VFLLV  CLILSV STI  + ++A + L  +E V+++ FG E+ IR+WSAGC  +Y G++GR+RFARKP  +ID +VL+AS  V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIFSS+ VYL E  +N++              F +YADALWWG IT+TTIGYGD  P TW+G+++++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQC+WR YA    S   +TWK + +    C   +      +S ++ S  F E       RMA     SI+ ++ S                G   S + D      +++G  +K Q+S   N      R  FR            +R   S  +P     T    +D  +E   +C    +  +LT   K  IR IR M+F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +GK  + S  DK+ R ++T          +L R+ ++E Q   ++SKLD +L
Sbjct:   76 RESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGW-AFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKE--------------FSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSQKLS--FKER-----VRMASPRGQSIKSRQASV---------------GDRRSPSTD-----ITAEGSPTKVQKSWSFND-----RTRFRP----------SLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVE--DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITS--DKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLL 624          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   20 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 308          

Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  419 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 519          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   20 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 308          

Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  419 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 519          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   61 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 349          

Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  460 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 560          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   61 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 349          

Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  460 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 560          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            + +IYN LE PTGWKCFLYHF+VFL+VLICLILSVLST++ +   A   L+ +EIVLV+FF  E+ +RLWSAGCRSKY+G  GR++F RKPI++IDLVV++ S  V+ FG++GQVFA SA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE    +D+  +   +      F SYADALWWGVIT+TTIGYGD VP+TW+G+I+ASCFS+FAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A   +  + +TW  +
Sbjct:   57 RAMIYNCLERPTGWKCFLYHFSVFLIVLICLILSVLSTVEEHSHFAAELLYILEIVLVVFFSVEFIVRLWSAGCRSKYIGVYGRLKFVRKPITLIDLVVVICSLFVICFGTEGQVFAASAMRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----KDHIGVDGRQA-----FTSYADALWWGVITMTTIGYGDVVPQTWLGRIVASCFSIFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAA--EKKVSATWNAH 345          

Query: 1730 ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLD 2032
            ELT+ H+ AIR IRR+++F+A RRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP     +  R    +T+ SRL+RLE Q   +D K++
Sbjct:  456 ELTDAHRNAIRAIRRVKYFVARRRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGQYDGKGSRKGHPVTIGSRLSRLELQMSSLDRKVE 556          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   58 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  420 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 595          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   24 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 309          

Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  386 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 561          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   58 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  420 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 595          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   55 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 340          

Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  417 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 592          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            Q+ +YNFLE P G     YH  VFL+V  CL LSV STI  Y E AV  LF MEI++VI+F  E+G RLWS+GCRS+Y G  GR++F ++P  +ID+V +LAS VVLG G+ GQVFATSA+RG+RF QILRM+ +DR+GGTW+LLGSVVY HRQELITT+YIGFLGLIF+S+ VY+ E   N+               F ++A ALWWGVIT+ T+GYGD VP TW GK+IASC ++  ISFFALPAGILGSGFALKVQQ+QRQKH  R+   AATLIQ +WRCYA    S   +TW I+
Sbjct:   58 QSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDK--------------FSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIH 343          

Query: 1688 EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRD--RTRLTVLSRLNRLESQSIKMDSKLDRIL----------LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT--LLHPTC 2221
            EE +  CT      +LT  HK AIR IR++++F+A R+F++A KPYDV+DV+EQY+ GH++++ R+K L  R+DQ +GK         +D   +++++ SR+ ++E Q   ++ KLD ++          L L   A   I++   SH      P H  +N +    V+++++  S +  Q  T  LL+P+ 
Sbjct:  435 EEDEPRCT------QLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGK----QGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSH-----KPLHHAHNLAMID-VWKRTAALSVHPEQVTTTPLLNPSA 610          

Query:  284 ITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYA-VSPDSNLHSTWKIYT 1255
            + +A R  L RS L         Q  +YNFLE PTGWKCF+YHF VFL+VL CLILSVLSTID Y+ +A  TLFWME+VLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL FGS GQVFATSA+RGVRFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D+ N         S F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRC+A ++PDS   +T+K++ 
Sbjct:   61 VYSATRPTLSRSFL---------QGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGN---------SGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDS---ATYKLFV 364          

Query: 1682 DTEESDSECTALRKPL----ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL----LLLSRIASCSI---NNQRSSHFRSDACPTHSVYNSS 2140
            D  E++ E   +  P+    +L + H+ AIRVI+RM +F+A ++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+D S+GK   F  S +  +D+   T+ SRLNR++ +   MD  L+ I     L+L+R     +     QRS+  R  A  + SV +SS
Sbjct:  465 DDMETEPEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNSIAESLNLMLARERRGDLARGKEQRSTMRRQSATFSLSVLDSS 630          

Query:  284 ITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYA-VSPDSNLHSTWKIYT 1255
            + +A R  L RS L         Q  +YNFLE PTGWKCF+YHF VFL+VL CLILSVLSTID Y+ +A  TLFWME+VLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL FGS GQVFATSA+RGVRFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D+ N         S F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRC+A ++PDS   +T+K++ 
Sbjct:   61 VYSATRPTLSRSFL---------QGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGN---------SGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDS---ATYKLFV 364          

Query: 1682 DTEESDSECTALRKPL----ELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL----LLLSRIASCSI---NNQRSSHFRSDACPTHSVYNSS 2140
            D  E++ E   +  P+    +L + H+ AIRVI+RM +F+A ++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+D S+GK   F  S +  +D+   T+ SRLNR++ +   MD  L+ I     L+L+R     +     QRS+  R  A  + SV +SS
Sbjct:  477 DDMETEPEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNSIAESLNLMLARERRGDLARGKEQRSTMRRQSATFSLSVLDSS 642          

Query:  284 ITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYA-VSPDSNLHSTWKIY 1252
            + +A R  L RS L         Q  +YNFLE PTGWKCF+YHF VFL+VL CLILSVLSTID Y+ +A  TLFWME+VLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL FGS GQVFATSA+RGVRFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D+ N         S F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRC+A ++PDS   +T+K++
Sbjct:   61 VYSATRPTLSRSFL---------QGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGN---------SGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDS---ATYKLF 363          

Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            S Q  +YNFLE P G +CFLYHF VFL+VL+CLI SVLSTI+ Y + A  +LFWMEIVLV+FFG EY +RLWSAGCRSKY+G +GR+RF RKPIS+IDL+V++AS VVL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+ +   F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWK+Y 
Sbjct:  115 SMQGDVYNFLERPAGLRCFLYHFLVFLMVLVCLIFSVLSTIEQYADFATGSLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIKGRLRFIRKPISIIDLIVVVASVVVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGKTG-FSSYADALWWGVVTVTTIGYGDKVPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYACEKSDSCTATWKMYV 408          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPD-SNLHSTWKIY 1252
            Q  +YN LE P GW  F+YH  VFLLV  CL+LSV STI  Y + + + L+ +EIV ++ FG EY +R+WSAGC  +Y G+RGR++FARKP  +ID++VL+AS  VL  G++G VFATSAIR +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LI +S+ VYLAE + NE               F++YADALWWG+IT+TTIGYGD  P TW G+++A+ F++  +SFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQ  WR YA + + ++L+STW  Y
Sbjct:   78 QNFLYNVLERPRGW-AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEDALYILEIVTIVVFGVEYIVRIWSAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASISVLAAGTQGNVFATSAIRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAEKEDNE--------------MFETYADALWWGLITLTTIGYGDKYPITWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQAAWRFYATNLNRTDLYSTWDYY 363          

Query: 1679 EDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTR-------LTVLSRLNRLESQSIKMDSKLD 2032
            ED  + +  C     P +LT   K+ IR +  M+F +++R+F+++ +PYDV DVIEQYS GHL+M+ RIK LQ R+DQ +G+    + +D+   T         +++ RL ++E Q + M+ KLD
Sbjct:  487 EDIVDDNKSCHCEFVPQDLTPGLKVTIRAVCIMRFMVSKRKFKESLRPYDVMDVIEQYSAGHLDMLARIKNLQSRVDQIVGRGAPITDKDRPKGTTDGELPEDPSMMGRLGKVEKQVMSMERKLD 611          

Query:  329 HMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            H     S Q  IYNFLE P+GW+CF+YHF+VFLLVLICLI SVLSTI+HY E A  TLFWMEIVLV+FFG EY IRLWSAGCRSKY+GF+GRIRFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+     F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWKIY
Sbjct:   78 HYLTRTSMQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGRTG-FSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIY 376          

Query: 1718 RKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR 1903
            RK + LTE H++A++V RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR
Sbjct:  396 RKQVRLTEAHRMAVKVTRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR 457          

Query:  329 HMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            H     S Q  IYNFLE P+GW+CF+YHF+VFLLVLICLI SVLSTI+HY E A  TLFWMEIVLV+FFG EY IRLWSAGCRSKY+GF+GRIRFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+     F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWKIY
Sbjct:   78 HYLTRTSMQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGRTG-FSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIY 376          

Query: 1661 RTISHQEDTE--ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            RT S+ +D +    +S   A+    +LTE H++A++V RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D S+GKP L   +   D+   TV SRL RLE +  +MD KLD IL + 
Sbjct:  479 RTNSYTDDIDGISEESALPAVTDLSQLTEAHRMAVKVTRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHSLGKPGLFLPEKGVDKGYYTVGSRLMRLEEKVNRMDHKLDEILCVF 610          

Query:  329 HMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            H     S Q  IYNFLE P+GW+CF+YHF+VFLLVLICLI SVLSTI+HY E A  TLFWMEIVLV+FFG EY IRLWSAGCRSKY+GF+GRIRFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + ++            + F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWKIY
Sbjct:   49 HYLTRTSMQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDEEGR---------TGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIY 347          

Query:  329 HMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            H     S Q  IYNFLE P+GW+CF+YHF+VFLLVLICLI SVLSTI+HY E A  TLFWMEIVLV+FFG EY IRLWSAGCRSKY+GF+GRIRFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+     F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA     +  +TWKIY
Sbjct:   78 HYLTRTSMQGDIYNFLERPSGWRCFIYHFSVFLLVLICLIFSVLSTIEHYSEFATGTLFWMEIVLVVFFGAEYLIRLWSAGCRSKYVGFKGRIRFARKPISIIDLIVVIASIIVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGRTG-FSSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYAAEKSYSSTATWKIY 376          

Query: 1733 LTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            LTE H++A++V RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D S+GKP L   +   D+   TV SRL RLE +  +MD KLD IL + 
Sbjct:  545 LTEAHRMAVKVTRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHSLGKPGLFLPEKGVDKGYYTVGSRLMRLEEKVNRMDHKLDEILCVF 650          

Query:  194 DKLENDEDRDEDYLLTKRKSELEKRRQSRMITN----AVRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISY-FKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            D   N + R +     ++    E +R++ + T+     + LD + SI +      +R  I   +YNFLE PTGWKCF+YHF VFL+VLICLI SVLSTI  Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE          K   DS   Y F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY
Sbjct:   49 DGSSNGQQRQD-----RQADTFELKRETLVTTDPPRPTINLDPRVSIYSGRRPLLTRTNIQGRVYNFLERPTGWKCFVYHFTVFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVLVVFFGAEYVVRLWSAGCRSKYVGIWGRLRFARKPISVIDLIVVVASIIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----------KDAIDSSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIY 392          

Query: 1733 LTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRM 1906
            L E H+ AI+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR 
Sbjct:  430 LKEHHRAAIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRF 487          

Query:  296 VRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            V LD + SI +      +R  I   +YNFLE PTGWKCF+YHF VFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY 
Sbjct:   84 VSLDPRVSIYSARRPLLARTHIQGRVYNFLERPTGWKCFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRIE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYV 395          

Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L + H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  480 RTNSFAEDLDLEGETLLTPITHVSQLRDHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIPISEKSKDRGSNTIGARLNRVEDKVTQLDQRLVIITDMLHQLLS 617          

Query:  296 VRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            V LD + SI +      +R  I   +YNFLE PTGWKCF+YHF VFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY 
Sbjct:   20 VSLDPRVSIYSARRPLLARTHIQGRVYNFLERPTGWKCFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRIE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYV 331          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDT-EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLT----------VLSRLNRLESQSIKMDSKLDRIL 2041
            Q  +YN LE P GW  F+YH  VFLLV  CLILSV STI  + ++A + L  +E V+++ FG E+ IR+WSAGC  +Y G++GR+RFARKP  +ID +VL+AS  V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIFSS+ VYL E  +N++              F +YADALWWG IT+TTIGYGD  P TW+G+++++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQC+WR YA    S   +TWK + +    C   +      +S ++ S  F E       RMA     SI+ ++ S                G   S + D      +++G  +K Q+S   N      R  FR            +R   S  +P     T    +D  +E   +C    +  +LT   K  IR IR M+F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +GK  + S  DK+ R ++T          +L+R+ ++E Q   ++SKLD +L
Sbjct:  113 QNYLYNVLERPRGW-AFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKE--------------FSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSQKLS--FKER-----VRMASPRGQSIKSRQASV---------------GDRRSPSTD-----ITAEGSPTKVQKSWSFND-----RTRFRP----------SLRLKSSQPKPVIDADTALGIDDVYDEKGCQCDVSVE--DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTS--DKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLL 625          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSH---FF------SEMRNASFK---RMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDT-EESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLT----------VLSRLNRLESQSIKMDSKLDRIL 2041
            Q  +YN LE P GW  F+YH  VFLLV  CLILSV STI  + ++A + L  +E V+++ FG E+ IR+WSAGC  +Y G++GR+RFARKP  +ID +VL+AS  V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL LIFSS+ VYL E  +N++              F +YADALWWG IT+TTIGYGD  P TW+G+++++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQC+WR YA    S   +TWK + +    C   +      +S +  S+   FF       + +  SFK   RMA     SI+ ++ S                G   S + D      +++G  +K Q+S   N      R  FR            +R   S  +P     T    +D  +E   +C    +  +LT   K  IR IR M+F +A+R+F++  +PYDV+DVIEQYS GHL+M+ RIK LQ R+DQ +GK  + S  DK+ R ++T          +L+R+ ++E Q   ++SKLD +L
Sbjct:  113 QNYLYNVLERPRGW-AFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKE--------------FSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSKFCSNKQKFFRVYTSRKQSQKLSFKERVRMASPRGQSIKSRQASV---------------GDRRSPSTD-----ITAEGSPTKVQKSWSFND-----RTRFRP----------SLRLKSSQPKPVIDADTALGIDDVYDEKGCQCDVSVE--DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQMTS--DKKSREKITAEHETTDDPSMLARVVKVEKQVQSIESKLDCLL 644          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVS-PDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSS-QGETSKEQESA------PPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTR----------LTVLSRLNRLESQSIKMDSKLD 2032
            Q  +YN LE P GW  F+YH  VFLLV  CL+LSV STI  Y + +   L+ +EIV ++ FG EY +R+W+AGC  +Y G+RGR++FARKP  +ID++VL+AS  VL  GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +EL+T  YIGFL LI +S+ VYLAE   N+              +F +YADALWWG+IT+TTIGYGD  P+TW G+++A+ F++  +SFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQ  WR YA +   ++LHSTW+ Y +  +           G      S     +      R  +  S    R+ P     P  + S       +  SS      +G  S Q +T +   SA       P+ +P       RS +  A       R   +A R    + ++  ++  E++ S C       +LT   K++IR +  M+F +++R+F+++ +PYDV DVIEQYS GHL+M+ RIK LQ R+DQ +G+    +  DK DRT+           +++ RL ++E Q + M+ KLD
Sbjct:   78 QNFLYNVLERPRGW-AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND--------------HFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGA-----SRLIPPLNQLELLRNLKSKSGLTFRKEPQ----PEPSPSQKVSLKDRVFSSPRGMAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRTRQA------FRIKGAASRQNSEEASLPGEDIVEDNKS-CNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRG--PTITDK-DRTKGPAETELPEDPSMMGRLGKVEKQVLSMEKKLD 621          

Query:  296 VRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            V LD + SI +      +R  I   +YNFLE PTGWKCF+YHFAVFL+VL CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   STWKIY 
Sbjct:   86 VSLDPRVSIYSARRPLLARTHIQGRVYNFLERPTGWKCFVYHFAVFLIVLACLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---STWKIYV 397          

Query: 1640 VRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            V P    RT S  ED + E ++  T +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  475 VSPTHFMRTNSFAEDLDLEGETLLTPITHVSQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIPISEKSKDRGSNTIGARLNRVEDKVTQLDQRLVVITDMLHQLLS 619          

Query:  218 RDEDYLLTKRKSELEKRRQSRMITNAVR----LDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISY-FKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            R ED    ++ +  E +R++ + T+  R    LD + SI +      SR  I   +YNFLE PTGWKCF+YHF VFL+VLICLI SVLSTI  Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE          K   DS   Y F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY
Sbjct:   49 RQED----RQANSFELKRETLVATDPPRPTINLDPRVSIYSGRRPLLSRTNIQGRVYNFLERPTGWKCFVYHFTVFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVLVVFFGAEYVVRLWSAGCRSKYVGVWGRLRFARKPISVIDLIVVVASVIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE----------KDAIDSSGEYQFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIY 385          

Query: 1619 VRASFSAVRPRRRK--RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIASCSINNQRSSHFRS 2104
            VR  F  + P      RT S  +D + E D+  T +    EL E H+ AI+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQS+GKP  FL      +D+   T+ SRLNR+E +  +MD KL+ I  +L  + +   N Q S   R+
Sbjct:  454 VRKPFGFLDPSTGPFIRTSSFTDDLDMEGDTLLTPITHISELKEHHRAAIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKPSLFLSVSDKVKDKGINTIGSRLNRVEDKVTQMDHKLNLITDMLHHLLT---NQQGSQSIRT 617          

Query:  296 VRLDLQRSILNHMNNTQSRQTI---IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            V LD + SI +      +R  I   +YNFLE PTGWKCF+YHF VFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   +TWKIY 
Sbjct:   84 VSLDPRVSIYSARRPLLARTHIQGRVYNFLERPTGWKCFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRIE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---ATWKIYV 395          

Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L + H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  480 RTNSFAEDLDLEGETLLTPITHVSQLRDHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIPISEKSKDRGSNTIGARLNRVEDKVTQLDQRLVIITDMLHQLLS 617          

Query:  362 IYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYT 1255
            +YNFLE PTGWKCF+YHFAVFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V+LAS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +P+S   STW IY 
Sbjct:   21 VYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYVALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGVWGRLRFARKPISIIDLIVVLASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGQVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPES---STWNIYV 307          

Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++    +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  392 RTNSVAEDLDLEGETPLVPITHVSQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVAQLDQRLVLITDMLQQLLS 529          

Query:  296 VRLDLQRSILNHMNNTQSR---QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIY 1252
            V LD + SI +      +R   Q  +YNFLE PTGWKCF+YHFAVFL+VL+CLI SVLSTI+ Y  +A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS VVL  GSKGQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +  ++  ++         F SYADALWWGV+TVTTIGYGD VP+TWVGK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ  WRCYA  +PDS   STWKIY
Sbjct:   85 VSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE---------FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS---STWKIY 395          

Query: 1661 RTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            RT S  ED + E ++  T +    +L E H+  I+VIRRMQ+F+A+++FQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQSIGKP  F+   +  +DR   T+ +RLNR+E +  ++D +L  I  +L ++ S
Sbjct:  481 RTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLS 618          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTIS-HQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRI 2059
            Q  +YNFLE PTGWKCF+YHF VF++VLICLI SVLSTID Y   A  TLFWMEIVLV+FFG EY IRLWSAGCRSKYMG RGR RFARKPIS+IDL+V++AS VVL  GS GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAE  +       KS+E +  + F SYADALWWGVITVTTIGYGD VP+TW+GKI+ASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYA  P S   +TW+I+T                ++ R +        +++F + ARRAS  I+++R S   F           +G      +D+ G    S+G            F P   R +  S +  A    G  R    A R  +    ++  + D+  SDS    L   L LTE HK AIRVIRR+++F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP       +RD+ ++T+++RL R+E+Q  K+D KLD +L LL+ I
Sbjct:   77 QGKVYNFLERPTGWKCFMYHFTVFMMVLICLIFSVLSTIDQYESFANETLFWMEIVLVVFFGLEYLIRLWSAGCRSKYMGARGRFRFARKPISIIDLIVVVASIVVLSVGSNGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAEKDA-------KSEEGT--TDFTSYADALWWGVITVTTIGYGDTVPQTWMGKIVASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAAEPRSLFLATWRIHT---------------QDAPRHHG-------SSAFIKAARRAS-LIKKRRFSKNRFDL---------SGSANHVASDRKG----SEGSIV---------FAPDESRTSSISGNHNALRRPGGRRDGTGAGRTEQTSAIVNISRIDSSTSDS----LSPRLTLTEAHKTAIRVIRRIRYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGAWMVSSERDKQKVTIVARLARVENQVNKIDQKLDSVLHLLNSI 588          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMR-NASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFR---SLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIAS 2065
            Q  +YNFLE PTGWKCF YHF VF +VLICLI SVLSTID Y + A  +LFWMEIVLV+FFG EY +RLWSAGCRSKYM F GR+RFARKPIS+IDL+V+  S +VL FGS GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAE  +N          D + S F SYADALWWGV+TVTTIGYGD VP+TW+G+I+ASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAAT+IQCLWRC+A        +TW                           HF  E R + S   MARRAS +  ++R S         ++     G  T  NN       ++ G + +  + +       P +P      SL     S   +++             T+  +  T+  D++     +PL+LT  HK AIRVIRR+++F+A+R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP +   ++K DR +LT+++RL+R+E+Q  KMD+KL+ IL LL+ + S
Sbjct:   51 QGRVYNFLERPTGWKCFAYHFTVFAMVLICLIFSVLSTIDQYEDFANESLFWMEIVLVVFFGFEYVVRLWSAGCRSKYMSFHGRLRFARKPISIIDLIVVTGSLIVLSFGSNGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAEKDAN----------DGKSSDFTSYADALWWGVVTVTTIGYGDTVPQTWIGRIVASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATIIQCLWRCHAAETHFRSQATWS-------------------------GHFLRENRPHLSLANMARRASATFVKRRRSAQKNSLEMPATGADHQGLQT--NNFLTVDAAATNGCSFRASDESILCSSGNPAKPTAEDTVSLRPVPNSAGMFLKVP-----------TLVPESSTDVDDADSAT--RPLQLTVAHKSAIRVIRRIKYFVAKRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGIMVSEEK-DRQKLTIIARLSRVENQIEKMDTKLEDILGLLNTVVS 574          

Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNAS-FKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAV---RPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLS 2053
            S Q  +YNFLE PTGWKCF+YHF VF++VLICLI SVLSTI  Y + A  TLFWMEIVLV+FFG EY IRLWSAGCRSKYMG RGR RFARKPIS+ID  V++AS VVL  GS GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAE  S ED              F SYADALWWGVITVTTIGYGD VPKTW+G+I+ASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP AATLIQCLWRC+A  P+ +  +TWKI+ Q                  + Y    +   ++S   RMAR+AS   +R+                            +N  GTSS G   + QES                             AS SAV    PR      + +   E+ D     + KP +LT+ HK  IRVIR+++FF+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ+IGKP      + RD+ +LT+ SR+ R+E+Q  KMD K+D+ ++LL+
Sbjct:    3 SLQVKVYNFLERPTGWKCFIYHFTVFMMVLICLIFSVLSTIQQYTDFANETLFWMEIVLVVFFGLEYVIRLWSAGCRSKYMGLRGRFRFARKPISIIDFTVVVASIVVLSAGSNGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAEKDSGED--------------FTSYADALWWGVITVTTIGYGDTVPKTWMGRIVASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPTAATLIQCLWRCHAAEPNVSSTATWKIHIQE-----------------KNYKMLVNNSTSSSALTRMARKASLLKKRK--------------------------GMRNSLGTSSGG--LERQESM----------------------------ASLSAVDMGTPRHS----AGKNSMEDDDDFDDLIFKPEQLTDGHKAMIRVIRKIKFFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTIGKPVYHG--NMRDKEKLTLCSRIGRIEAQVTKMDHKMDQTIVLLN 482          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLS 2053
            Q  +YNFLE PTGWKCF+YHF VF++VLICLI SVLSTID Y   A+ TL++MEIVLV FFG EY +RLWSAGCRSKYMG +GRIRFARKPIS+IDL+V++AS  V   GS+GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSV+Y+HRQELITTLYIGFLGLIFSSYFVYLAE     D+             F SYADALWWGVITV TIGYGD VP+TW+GKI+ASCF+VFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQC+WRCYA  P SN  +TWKI+                           S        RMARRAS ++R++R S +     + S       +  +S   ++  GT      S  ++S+ PN +             +    +G                   + +  ++ + +   + K ++LT+ HK AIRV+R++++F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP        +DR R+T+ +R+ R+E+Q  K D KLD+++ LL+
Sbjct:   87 QAQLYNFLERPTGWKCFIYHFTVFMMVLICLIFSVLSTIDQYAGFAMETLYYMEIVLVCFFGVEYVVRLWSAGCRSKYMGMKGRIRFARKPISIIDLIVVVASIGVFSVGSEGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVIYLHRQELITTLYIGFLGLIFSSYFVYLAERDEGRDD-------------FSSYADALWWGVITVMTIGYGDKVPQTWMGKIVASCFAVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCVWRCYAADPTSNSEATWKIHIHD------------------------SSNEETMLARMARRASLTLRKRRSSRM----DSISIGNHVRRESLTSFYQEDKIGTPR----SNRRDSSRPNMM-------------SNHPNVG------------------GNDQYEDQMEYDLDDVEKVVQLTDAHKTAIRVLRKIKYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPGTLYSNCYKDRERMTIGARIVRMETQMQKTDQKLDQVIFLLN 577          

Query:  335 NNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQ 2005
            N+ QSR   +YNFLE PTGWKCF+YHF VF++VLICLI SVLSTID Y + A+ TLFWMEI LV FFG EY IRLWSAGCRSKYMG RGR RF+RKPIS+IDL+V++AS VV   GS+GQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSV+Y+HRQELITTLYIGFLGLIFSSYFVYLAE    E ++            FKSYADALWWGVITV TIGYGD VP+TW+GKI+ASCF+VFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRC+A +P S   +TWKI+                                  F +MARRAS ++R++R S L                D+SS    +     S    +   E   P    +  R + R   C A                        +  + +  +    ++ K ++LTE HK AIRVIR++++F++ RRFQ  RKPYDVRDVIEQYSQGHLNMMVRIKELQRR+DQ++GKP        RDR ++T+ +R+ R+E+Q
Sbjct:   95 NSIQSR---VYNFLERPTGWKCFIYHFTVFMMVLICLIFSVLSTIDQYTKFAMETLFWMEIFLVCFFGAEYVIRLWSAGCRSKYMGIRGRFRFSRKPISIIDLIVVVASIVVFTVGSEGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVIYLHRQELITTLYIGFLGLIFSSYFVYLAERGEEERDD------------FKSYADALWWGVITVMTIGYGDKVPQTWMGKIVASCFAVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCHAAAPGSKSEATWKIHVHDPGS------------------------EETMFAKMARRASLTLRKRRMSRL----------------DSSSTVANHSVYRESVSSITYADEKPGPLTPRILRRDSHRPSICGAN----------------------ENNYNDDTDNDLDDSMEKVVQLTEAHKTAIRVIRKIKYFVSRRRFQATRKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDQTLGKPSNLYSSQARDREKMTIGARMVRVENQ 574          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFP-FXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPP-NFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGK-PFLRSCQDK-RDRTRLTVLSRLNRLESQSIKMDSKLDRIL-----LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSS 2170
            Q  +YNFLE P+GWKCF+YHF VFL+VL CLILSVLSTI+ Y+ +A +TLFW+EIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIF+SYFVYLAE  + + +          ++ F SYADALWWGV+TVTTIGYGD VP+TW+GK I SCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+A+ +PDS   ST+K++ +      +P                 S  +     +M R+   S +   PS+   P  + +   G    QDT  + D +G     + +  +   S     F P P++          + GI  +++      P +R  + +   + E E DS    +    +L E H+ AIRVI+RM++F+A++RFQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQS+GK    ++  D+ +D+   T+ SRLNR+E +   MD  L+ I      LL+       +     S   S++ P++   +++T P   ++SS
Sbjct:   86 QGRVYNFLERPSGWKCFVYHFTVFLIVLSCLILSVLSTIEEYQTLAQDTLFWVEIVLVVFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISIIDLIVVVASVIVLSVGSNGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLALIFASYFVYLAEKDAVDGDG---------VTEFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIGSCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTSWRCFAIENPDS---STYKMFVRRKPMTAHPSA---------------SSPKAKKTVKMRRKVKTSEKDNGPSSPTIPTITYDFDEGRDPSQDTVYSTDMSGAAALRRLDRQQSWTSITSFQFSPPPVK---------KSPGILEIQSH----PPLQRNSSFADDLELEAERDSILLPVTHVSQLRESHRAAIRVIQRMRYFVAKKRFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKITLFQTGSDRAKDKGLNTIGSRLNRMEEKITHMDKTLNCIAESLNSLLMRDSGRIGLAEAGPSLSASNSLPSYDQLSTTTFPSALEESS 662          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFP-FXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPP-NFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGK-PFLRSCQDK-RDRTRLTVLSRLNRLESQSIKMDSKLDRIL-----LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSS 2170
            Q  +YNFLE P+GWKCF+YHF VFL+VL CLILSVLSTI+ Y+ +A +TLFW+EIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIF+SYFVYLAE  + + +          ++ F SYADALWWGV+TVTTIGYGD VP+TW+GK I SCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+A+ +PDS   ST+K++ +      +P                 S  +     +M R+   S +   PS+   P  + +   G    QDT  + D +G     + +  +   S     F P P++          + GI  +++      P +R  + +   + E E DS    +    +L E H+ AIRVI+RM++F+A++RFQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQS+GK    ++  D+ +D+   T+ SRLNR+E +   MD  L+ I      LL+       +     S   S++ P++   +++T P   ++SS
Sbjct:   61 QGRVYNFLERPSGWKCFVYHFTVFLIVLSCLILSVLSTIEEYQTLAQDTLFWVEIVLVVFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISIIDLIVVVASVIVLSVGSNGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLALIFASYFVYLAEKDAVDGDG---------VTEFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIGSCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTSWRCFAIENPDS---STYKMFVRRKPMTAHPSA---------------SSPKAKKTVKMRRKVKTSEKDNGPSSPTIPTITYDFDEGRDPSQDTVYSTDMSGAAALRRLDRQQSWTSITSFQFSPPPVK---------KSPGILEIQSH----PPLQRNSSFADDLELEAERDSILLPVTHVSQLRESHRAAIRVIQRMRYFVAKKRFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKITLFQTGSDRAKDKGLNTIGSRLNRMEEKITHMDKTLNCIAESLNSLLMRDSGRIGLAEAGPSLSASNSLPSYDQLSTTTFPSALEESS 637          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV-SPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFP-FXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGK-PFLRSCQDK-RDRTRLTVLSRLNRLESQSIKMDSKLDRIL-----LLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSS 2170
            Q  +YNFLE P+GWKCF+YHF VFL+VL CLILSVLSTI+ Y+ +A +TLFW+EIVLV+FFG EY +RLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GS GQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIF+SYFVYLAE  + + +          ++ F SYADALWWGV+TVTTIGYGD VP+TW+GK I SCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+A+ +PDS   ST+K++ +      +P                 S  +     +M R+   S +   PS+   P  + +   G    QDT  + D + +  S    TS +       F P P++          + GI  +++      P +R  + +   + E E DS    +    +L E H+ AIRVI+RM++F+A++RFQQARKPYDVRDVIEQYSQGHLN+MVRIKELQRR+DQS+GK    ++  D+ +D+   T+ SRLNR+E +   MD  L+ I      LL+       +     S   S++ P++   +++T P   ++SS
Sbjct:   86 QGRVYNFLERPSGWKCFVYHFTVFLIVLSCLILSVLSTIEEYQTLAQDTLFWVEIVLVVFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISIIDLIVVVASVIVLSVGSNGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLALIFASYFVYLAEKDAVDGDG---------VTEFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIGSCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTSWRCFAIENPDS---STYKMFVRRKPMTAHPSA---------------SSPKAKKTVKMRRKVKTSEKDNGPSSPTIPTITYDFDEGRDPSQDTVYSTDMSDRQQSWTSITSFQ-------FSPPPVK---------KSPGILEIQSH----PPLQRNSSFADDLELEAERDSILLPVTHVSQLRESHRAAIRVIQRMRYFVAKKRFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSLGKITLFQTGSDRAKDKGLNTIGSRLNRMEEKITHMDKTLNCIAESLNSLLMRDSGRIGLAEAGPSLSASNSLPSYDQLSTTTFPSALEESS 654          

Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRN-ASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGET-----SKEQESAPPNFI--PLPLRPAFR-----------SLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            S Q  +YNFLE P G KCFLYHF VFL+VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G +GR+RF RKPIS+IDL+V++AS VVL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D            + F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA        +TWK+Y                  +G       SE  +  +F+++++R    ++  R                    D  S  +   +  S    T      KE +   P F+  P  +   FR           +LSC A+     V+          R  ++    D         A+    +L+  H+ AI+VIRRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D ++GKP L   +   D+   TV +RL RLE + ++MD K++ IL +L
Sbjct:  141 SMQGDVYNFLERPAGLKCFLYHFLVFLMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIKGRLRFIRKPISIIDLIVVVASVVVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDEGK---------TGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYACEKPDGCPATWKMYV----------------LTGDYIPVINSENSSPGNFRKLSKRYKRRLKSTR--------------------DNGSLGNAGEKALSIPQITYDHIDDKEDKREVPFFLEEPPGITKIFRQTARHHSWSSFNLSCPASP----VKKKLDGHPDISRTNSLVDDIDFASEFIPLPAVTDASQLSHAHRSAIKVIRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHTLGKPGLFLPEKGVDKEFHTVGARLIRLEDKVLQMDQKVENILKIL 678          

Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            S Q  +YNFLE P G KCFLYHF VFL+VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY+G +GR+RF RKPIS+IDL+V++AS VVL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  + +D            + F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQ LWRCYA        +TWK+Y 
Sbjct:  141 SMQGDVYNFLERPAGLKCFLYHFLVFLMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGIKGRLRFIRKPISIIDLIVVVASVVVLSVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDEGK---------TGFSSYADALWWGVVTVTTIGYGDKVPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTLWRCYACEKPDGCPATWKMYV 434          

Query: 1733 LTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            L+  H+ AI+VIRRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D ++GKP L   +   D+   TV +RL RLE + ++MD K++ IL +L
Sbjct:  579 LSHAHRSAIKVIRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDHTLGKPGLFLPEKGVDKEFHTVGARLIRLEDKVLQMDQKVENILKIL 684          

Query:  512 EIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKN--GQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRF-QQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQ 2005
            EI LV+FFG EY +RLWSAGCRSKY+G  GR+RFA KPIS+IDLVV++AS +VL  GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE            DE  E + F SYADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQ LWRC+    D +  +TW I    H +  + +        GR +       R A  K   +R    I++ +   L  P       G   G  TS  N  N    GT+S    +  Q  AP            RSL  T+T              PR               D     L     LTE HK+AIRVIRRMQ+F+A  +F QQA+KPYDVRDVIEQYSQGH+NMMVRIKELQRR+D S+GKP +   +  +DR++ T+ +RL+R+E +
Sbjct:    1 EIALVVFFGVEYLVRLWSAGCRSKYVGVMGRVRFAHKPISIIDLVVVVASIIVLCVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEK-----------DEAREKNEFASYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQSLWRCHLAESDHHSTATWMI--DAHFNGISAKTAEHVTWEGRVH-------RLAKEKEDKKRKKQLIKQAKGDGLVSP-------GARQGSSTSEGNHANTPDNGTNS---ATGWQPDAP------------RSLYHTST--------------PRSPPLLCDQPTPPTPPDLH---LHSACGLTESHKIAIRVIRRMQYFVARSKFQQQAKKPYDVRDVIEQYSQGHVNMMVRIKELQRRLDHSLGKPNMFLSEKGKDRSKYTIGARLDRVEEK 442          

Query:  512 EIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPD-SNLHSTWKIY 1252
            E ++++ FG EY  R+W+AGC  +Y G+RGR++F+RKP  +ID++VL+AS  VL  G++G VFATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL L+FSS+ VYLAE   N+               F +YADALWWG IT+TTIGYGD  P TWVG+++A+ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA LIQ  WR ++      +L +TW+ Y
Sbjct:   19 EYIMIVVFGIEYIARIWAAGCCCRYRGWRGRLKFSRKPFCVIDIIVLIASLAVLAAGTQGNVFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLVFSSFLVYLAEKDENQKE-------------FGTYADALWWGTITLTTIGYGDKCPVTWVGRLMAASFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRSPAAGLIQAAWRLHSTDASRPHLIATWRFY 253          

Query:  467 IDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPA 1093
            I ++R + ++     E ++++ FG EY +R+W+AGC  +Y G++GR+RFARKP  +ID +VL+AS  V+  G++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL L+FSS+ VYLAE   N+D              F +YADALWWG IT+TTIGYGD  PKTW+G+++A+ F++  ISFFALPA
Sbjct:    2 IKNHRSLGISCAVPQEGIMMVLFGLEYFLRIWAAGCCCRYRGWQGRLRFARKPFCIIDSIVLVASLAVIAAGTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLALVFSSFLVYLAEKDDNKDQ-------------FATYADALWWGTITLTTIGYGDKTPKTWLGRMLAAGFALLGISFFALPA 197          

Query:  512 EIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGV---------ITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPA 1093
            E ++++ FG EY +R+W+AGC  +Y G++GR+RFARKP  +ID +VL+AS  V+  G++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVVY H +ELIT  YIGFL L+FSS+ VYLAE   N+D              F +YADALWWG          IT+TTIGYGD  PKTW+G+++A+ F++  ISFFALPA
Sbjct:    6 EGIMMVLFGLEYFLRIWAAGCCCRYRGWQGRLRFARKPFCIIDSIVLVASLAVIAAGTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLALVFSSFLVYLAEKDDNKDQ-------------FATYADALWWGTGWGLLVLADITLTTIGYGDKTPKTWLGRMLAAGFALLGISFFALPA 195          

Query:  464 TIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVY 802
            TI  Y++ A   +    ++++  FG EY  R+W+AGC  +Y G+RGR RFARKP  +ID++VL+AS  V+  G++G VFATSA+R +RFLQILRM+ +DR+GGTWRLLGSVVY
Sbjct:   15 TIQTYQDAASKAVL---LLMIGVFGLEYFARIWAAGCCCRYRGWRGRCRFARKPFCVIDIIVLIASLAVIIAGTQGNVFATSALRSLRFLQILRMVRMDRRGGTWRLLGSVVY 124          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQ 1189
            Q   YNFLE P G    +YH A+ +LV++ LIL+ LST++ Y  +    +F +EIVLV  F  EYG+RLWSAGCRS Y+G RGR+ FA+K  +++D++V+ +S   L   + G   ++  +R VRFL +LR+L  DRQG TW+LL SV+YIHR+EL+TTLY+GF+ LIF+S+ +Y+ E   N                F S+ ++ WWG++T+TTIGYGD  P TW G++ AS F+V  ISFFALPAGILGSGFALKV Q+QRQKHF+R+   AA L+Q
Sbjct:    5 QLYCYNFLERPRGLA-IVYHVALCILVIVSLILTALSTVNIYEALLDTPIFIVEIVLVTVFIVEYGLRLWSAGCRSTYVGLRGRLNFAKKTYAILDVLVIFSSIAGLALSTNG---SSITVRLVRFLPLLRVLRFDRQGSTWKLLASVIYIHRKELLTTLYLGFISLIFASFVLYMVEKDENVK--------------FDSWPNSFWWGIVTLTTIGYGDKTPITWYGRLCASIFAVCGISFFALPAGILGSGFALKVTQQQRQKHFHRRRRPAAILLQ 265          

Query:  464 TIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGF 1114
            +I +   +A N    +E+   I+F  E   RL SA           +I+F ++P++++D++ +L   +VL    K +  + S +R  R L++LR+  + R     R+L     +   EL   +    + ++ SS   Y AE                    F+S   A WW + TVTT+GYGD  P T  GKI+ S  SVF +   ALP  +  S F
Sbjct:  179 SIGNSNVLATNVYVIIEMACYIWFTIELIFRLASAP---------EKIKFCKQPLNVVDILTVLPYYIVLAV-EKSRTGSLSVMRAARMLRVLRIFKLSRYSSGMRVLLYTFLMSLNELWMFMLFAGMSVLLSSAAAYYAETAHGRQT-------------FESIPGAFWWSISTVTTVGYGDQYPLTASGKIVGSILSVFGVLVVALPVFLFVSNF 372          

Query:  503 FWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGF-GSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVF-AISFFALPAGILGSGF 1114
            F ++  ++ +F  EY  RL SA           +++F    +++IDL+ ++   + LG    +      + +R  R L+++R+L + R     R+LG  +   + +L   +++  + +I  S  +Y  EN+ N                F S   A WW +IT+TT+GYGD  P+T  G+++ +C +VF  I    LP  +    F
Sbjct:  207 FVIDTCIITWFTSEYIARLISAP---------HKLKFVFSTLALIDLIAIIPYFISLGLDADQTHAITFTVLRIFRLLRVIRLLKLTRYVAALRILGYTIQSCQDQLTALMFLLLISIILFSSLMYYLENEENPTE-------------FYSIPAAFWWCIITMTTVGYGDTCPRTPFGRLVGACCAVFGVIVMVCLPTPVFILHF 390          

Query:  464 TIDHYREVAVNTLFW-MEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQ 1138
            T DH   V  ++ +  +EI+ + +F  EY +RL S+           ++ F R  +++IDL+ +L   + L      ++ + + +R +R +++ R+  + R     ++LG  +    +EL   ++   + ++  S  VY AE             E+   S F S  DA WW V+T+TT+GYGD  P T  GK++ S  ++  +   ALP  ++ S F    +++Q
Sbjct:  177 TADHPEPVEKSSAWLALEILCIAWFTLEYVVRLLSSP---------QKLLFVRSFLNVIDLMAILPYYITLPMKDL-RITSLAVLRVIRLVRVFRIFKLSRHSRGLQVLGHTLRASSRELAMLIFFLLISVVLFSSAVYYAE-------------EEEAASKFSSIPDAFWWAVVTMTTVGYGDMYPVTPWGKLVGSICAISGVLTIALPVPVIVSNFNYFYKREQ 379          

Query:  467 IDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFG-SKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGF 1114
            +DHY     +  F +E   V +F  E+ +R+W++ C            F +    ++D+  ++   + L    S   V + + IR +R  +++R+  + R     +LL   +Y   ++L + L+   + +I  S  +Y  ++K N                  S   A WW VIT+T++GYGD VP T  GK++ S  ++  +  F LP  +L S F
Sbjct:  193 VDHY---FTDYWFVIEAYCVAWFTVEFVVRMWASPCTW---------LFVKSWFGVLDVAAIVPFYITLALKESTYGVRSFAVIRALRLFRVIRIFKLSRYSDALKLLVKTLYSSSEQLRSLLFCFLVAIILFSSIIYYVDDKDN----------------IPSIPHAFWWSVITMTSVGYGDVVPSTIAGKLVGSLCAMSGLILFCLPTPVLVSNF 381          

Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            S Q  +YNFLE P G KCFLYHF VF++VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY G +GR+RF RKPIS+IDL+V++AS +VLG GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+ +   F SYADALWWGV+TVTTIGYGD +P+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ LWRCYA    +   +TWK+Y                 ++G       +  +  + +R   R   S+       +  P            +   S   K   GT  +G     ++S PP+        +  +LSC  +   G    S S      R  +++ + D    D     +    +L+   + A++V+RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D ++GKP +       D+   T+ +++ RLE +  +MD K+D +L +L
Sbjct:  141 SMQGDVYNFLERPAGMKCFLYHFLVFIMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVLFFGTEYVVRLWSAGCRSKYAGIKGRLRFIRKPISIIDLIVVIASIIVLGVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGKTG-FSSYADALWWGVVTVTTIGYGDKIPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTLWRCYAAEKPNGCAATWKMYV-----LTPEGIAAAAADNGSPSIKKLNMAKKGTKRRPKSRGFASMGVASERAVSIPQITYDHIDDSEEKKDMSFFLKEQTGT-VEGIARMFRKSGPPHH-----SWSSFTLSCPTSPEKGSHEKSTSI--DISRANSLTDELDDMSEDIPLPVVTNKNQLSHAQRSAVKVLRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDGTLGKPGMFLPGKGEDKEYHTIGAQMIRLEEKIHQMDLKMDSVLRIL 686          

Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            S Q  +YNFLE P G KCFLYHF VF++VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY G +GR+RF RKPIS+IDL+V++AS +VLG GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+ +   F SYADALWWGV+TVTTIGYGD +P+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ LWRCYA    +   +TWK+Y 
Sbjct:  141 SMQGDVYNFLERPAGMKCFLYHFLVFIMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVLFFGTEYVVRLWSAGCRSKYAGIKGRLRFIRKPISIIDLIVVIASIIVLGVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGKTG-FSSYADALWWGVVTVTTIGYGDKIPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTLWRCYAAEKPNGCAATWKMYV 434          

Query: 1655 RKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLL 2050
            R  +++ + D    D     +    +L+   + A++V+RRMQ+F+A R+FQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRR+D ++GKP +       D+   T+ +++ RLE +  +MD K+D +L +L
Sbjct:  528 RANSLTDELDDMSEDIPLPVVTNKNQLSHAQRSAVKVLRRMQYFVARRKFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRLDGTLGKPGMFLPGKGEDKEYHTIGAQMIRLEEKIHQMDLKMDSVLRIL 659          

Query:  347 SRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIY 1252
            S Q  +YNFLE P G KCFLYHF VF++VL+CLI SVLSTI+ Y + A  TLFWMEIVLV+FFG EY +RLWSAGCRSKY G +GR+RF RKPIS+IDL+V++AS +VLG GS GQVFATSAIRG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFLGLIFSSYFVYLAE  +         DE+ +   F SYADALWWGV+TVTTIGYGD +P+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ LWRCYA    +   +TWK+Y
Sbjct:  141 SMQGDVYNFLERPAGMKCFLYHFLVFIMVLVCLIFSVLSTIEQYADFATGTLFWMEIVLVLFFGTEYVVRLWSAGCRSKYAGIKGRLRFIRKPISIIDLIVVIASIIVLGVGSNGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA--------VDEEGKTG-FSSYADALWWGVVTVTTIGYGDKIPQTWIGKAIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTLWRCYAAEKPNGCAATWKMY 433          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV 1213
            Q  +YNFLE PTGW+CF+YHF VFL+VL CLILSVLSTID ++ +A  TLFW+EIVLV+FFG EY IRLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GSKGQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIFSSYFVYLAE  +          + S  + F +YADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+AV
Sbjct:  100 QGRVYNFLERPTGWRCFVYHFTVFLIVLACLILSVLSTIDQFQALAHTTLFWVEIVLVVFFGVEYFIRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASIIVLSVGSKGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLSLIFSSYFVYLAEKDAV---------DSSGATEFGNYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTAWRCFAV 377          

Query: 1523 KEQESAPPNFIPLPLRPAF---RSLSCTATSGIGYVR-----ASFSAVRPRRRKRTISHQEDTE-ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            K+   A P    +   P F   R LS    S +G V+         ++ P RR  + +   + E E D+E +       LTE H+ AIRV++RM++F+A+R+FQQARKPYDVRDVIEQYSQGH+N+MVRIKELQRR+DQS+GK   F       RD+   ++ SRLNR+E +   MD  L  I+
Sbjct:  420 KDNGPASPTMPGVTHDPVFDSGRELSSDVYSSVGTVKRNAGILDVHSMTPIRRNCSFADDLELESERDTELSPASSISHLTESHRKAIRVVQRMRYFVAKRKFQQARKPYDVRDVIEQYSQGHVNLMVRIKELQRRLDQSLGKMTLFQTGTDRARDKGNNSIGSRLNRMEDKISHMDQTLTLIM 603          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAV 1213
            Q  +YNFLE PTGW+CF+YHF VFL+VL CLILSVLSTID ++ +A  TLFW+EIVLV+FFG EY IRLWSAGCRSKY+G  GR+RFARKPIS+IDL+V++AS +VL  GSKGQVFATSA+RG+RFLQILRMLHVDRQGGTWRLLGSVV+IHRQELITTLYIGFL LIFSSYFVYLAE  +          + S  + F +YADALWWGV+TVTTIGYGD VP+TW+GK IASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQ  WRC+AV
Sbjct:  100 QGRVYNFLERPTGWRCFVYHFTVFLIVLACLILSVLSTIDQFQALAHTTLFWVEIVLVVFFGVEYFIRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASIIVLSVGSKGQVFATSAVRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLSLIFSSYFVYLAEKDAV---------DSSGATEFGNYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAACLIQTAWRCFAV 377          

Query: 1658 KRTISHQEDTE---ESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKP--FLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            +R  S  +D E   E D+E +       LTE H+ AIRV++RM++F+A+R+FQQARKPYDVRDVIEQYSQGH+N+MVRIKELQRR+DQS+GK   F       RD+   ++ SRLNR+E +   MD  L  I+
Sbjct:  490 RRNCSFADDLELESERDTELSPASSISHLTESHRKAIRVVQRMRYFVAKRKFQQARKPYDVRDVIEQYSQGHVNLMVRIKELQRRLDQSLGKMTLFQTGTDRARDKGNNSIGSRLNRMEDKISHMDQTLTLIM 622          

Query:   95 MALRYNSDNHIINIHDEKIEVRIIDNETSQIVYDKLENDEDRDEDYLLTKRKSELEKRRQSRMITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQTLLHPTCSGKLLRSSSFSTSQIPQISEKEKTSNVNSFLKQKVFRSQSTKVSKKTHLSPDSKFDRKDSMKHPHFTKNLSVEETEQTVSPGEKPQICECSSYAQFTTNINQCSASFIPAXXXXXXXXXXMYTPSPEFLSSPEFCDMREPQRVMSAINIXXXXXXXXXXXXXXXQTTMTTELIQTDNQEKIILNVPNINMEADISDILRRRNTPSFVFP 2848
            MA RYNSDNHIINIHDEKIEVRIIDNETSQIVYDKLENDEDRDEDYLLTKRKSELEKRRQSRMITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFLLVLICLILSVLSTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTQLHSHCHNPQHHHQNGNSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFSNNSSNGGGAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT LHPTCSGKLLRSSSFSTSQIPQISEKEKTSNVNSFLKQKVFRSQSTKVSKKTHLSPDSKFDRKDSMKHPHFTKNLSVEETEQTVSPGEKPQICECSSYAQFTTNINQCSASFIPALSSPPSLNSSMYTPSPEFLSSPEFCDMREPQRVMSAINISAPVTPPPPVSTYAYQTTMTTELIQTDNQEKIILNVPNINMEADISDILRRRNTPSFVFP
Sbjct:    1 MASRYNSDNHIINIHDEKIEVRIIDNETSQIVYDKLENDEDRDEDYLLTKRKSELEKRRQSRMITNAVRLDLQRSILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFLLVLICLILSVLSTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTQLHSHCHNPQHHHQNGNSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFSNNSSNGGGAGQDTSSNNDKNGQGTSSQGETSKEQESAPPNFIPLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRILLLLSRIASCSINNQRSSHFRSDACPTHSVYNSSTGPVVYQKSSQPSENQTQCQT-LHPTCSGKLLRSSSFSTSQIPQISEKEKTSNVNSFLKQKVFRSQSTKVSKKTHLSPDSKFDRKDSMKHPHFTKNLSVEETEQTVSPGEKPQICECSSYAQFTTNINQCSASFIPALSSPPSLNSSMYTPSPEFLSSPEFCDMREPQRVMSAINISAPVTPPPPVSTYAYQTTMTTELIQTDNQEKIILNVPNINMEADISDILRRRNTPSFVFP 917          

Query:  353 QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            +T IYNFLE PTGWKCFLYHF VF++VL+CLI SV+STID Y E++   L+ ME +LV FFG EY IRLWS+GCRSKY+GF GR+RF RKPIS+IDL+V++AS +VL FGSKG+VFATSAIRG+RF+QILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGL+FSSYFVYL+EN SNE +N            F SYADALWWGV+TVTTIGYGD VPKTW+GKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQCLWR +A S   N  +TW+IYT
Sbjct:   51 KTKIYNFLERPTGWKCFLYHFTVFIMVLVCLIFSVISTIDVYYEMSSYLLYIMETILVFFFGAEYIIRLWSSGCRSKYLGFSGRLRFMRKPISLIDLIVVVASFIVLLFGSKGKVFATSAIRGIRFMQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLVFSSYFVYLSEN-SNEPSNE-----------FMSYADALWWGVVTVTTIGYGDKVPKTWIGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAANLIQCLWRLHASSVKFNSVATWRIYT 339          

Query: 1628 SFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            S+   RP  RK    H   T+E +      R+P+ L    K+AIRV+RRM++++A R+FQQ RKPYDV+DVIEQYSQGHLNMMVR+KELQRR+DQ++GKP   + ++  DR R+T+  RL  +E +   ++SK+   L
Sbjct:  356 SYPHTRPNTRKNL--HDLFTKEKNE---IRREPINLNSSQKVAIRVLRRMRYYVARRKFQQTRKPYDVKDVIEQYSQGHLNMMVRLKELQRRLDQTLGKP---AHRNNIDRHRMTIAQRLLVIEYKITDLESKVAETL 485          

Query:  107 YNSDNHIINIHDEKIEVRIIDNETSQIVYDKLENDEDRDEDYLLTKRKSELEKRRQSRMITNAVRLDLQR-SILNHMNNTQSRQTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            + S   +IN H++ + + + DNE          N  D   +  + KR S L  +            D Q+ SI        S QT +YNFLE PTGWKCFLYHF VFL+VLICLILSVLST+++Y E+A+  LF ME++L+IFF  E+ IRLWSAGCRSK++G  GR++F +KPIS+IDLVV++AS  VL  G+KGQVFATSAIRG+RFLQILRMLHVDRQG TWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFV+LAEN + +             + F SYAD+LWWGV+TVTTIGYGD VPKTW+GKI+ASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA+LIQCLWR YA S   N  +TWKIYT
Sbjct:   50 FQSMPGLINSHNDSLTIDL-DNE----------NGSDLKVNEKVRKRLSSLFGK------------DWQKISIFTSYRAKLSFQTKVYNFLERPTGWKCFLYHFTVFLMVLICLILSVLSTVEYYSEMAIELLFIMEMILLIFFTTEFSIRLWSAGCRSKFLGLSGRLKFIKKPISIIDLVVIIASMTVLIAGTKGQVFATSAIRGIRFLQILRMLHVDRQGSTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVFLAENATEQS------------AEFISYADSLWWGVVTVTTIGYGDKVPKTWIGKIVASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQCLWRLYASSNKKNSEATWKIYT 398          

Query:  509 MEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYT 1255
            +E +LV FFG EY IRLWS+GCRSKY+GF GR+RF RKPIS+IDL+V++AS +VL FGSKG+VFATSAIRG+RF+QILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGL+FSSYFVYL+EN SNE +N            F SYADALWWGV+TVTTIGYGD VPKTW+GKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAA LIQCLWR +A S   N  +TW+IYT
Sbjct:   71 LETILVFFFGAEYIIRLWSSGCRSKYLGFSGRLRFMRKPISLIDLIVVVASFIVLLFGSKGKVFATSAIRGIRFMQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLVFSSYFVYLSEN-SNEPSNE-----------FMSYADALWWGVVTVTTIGYGDKVPKTWIGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAANLIQCLWRLHASSVKFNSVATWRIYT 307          

Query: 1628 SFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            S+   RP  RK    H   T+E +      R+P+ L    K+AIRV+RRM++++A R+FQQ RKPYDV+DVIEQYSQGHLNMMVR+KELQRR+DQ++GKP   + ++  DR R+T+  RL  +E +   ++SK+   L
Sbjct:  324 SYPHTRPNTRKNL--HDLFTKEKNE---IRREPINLNSSQKVAIRVLRRMRYYVARRKFQQTRKPYDVKDVIEQYSQGHLNMMVRLKELQRRLDQTLGKP---AHRNNIDRHRMTIAQRLLVIEYKITDLESKVAETL 453          

Query:  248 KSELEKRRQSRMITNAVRLDLQRSILN---HMNNTQSR--QTIIYNFLEFPTGWKCFLYHFAVFXXXXXXXXXXXXXTIDHYREVAVNTLFWMEIVLVIFFGCEYGIRLWSAGCRSKYMGFRGRIRFARKPISMIDLVVLLASCVVLGFGSKGQVFATSAIRGVRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLGLIFSSYFVYLAENKSNEDNNNLKSDEDSEISYFKSYADALWWGVITVTTIGYGDAVPKTWVGKIIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAATLIQCLWRCYAVSPDSNLHSTWKIYTXXXXXXXXXXXXXXXXXSGRRYSHFFSEMRNASFKRMARRASNSIRRQRPSTLFFPFXXXXXXXXXAGQDTSSNNDKNGQGTSSQGETSKE--QESAPPNFI--PLPLRPAFRSLSCTATSGIGYVRASFSAVRPRRRKRTISHQEDTEESDSECTALRKPLELTEDHKLAIRVIRRMQFFLAERRFQQARKPYDVRDVIEQYSQGHLNMMVRIKELQRRMDQSIGKPFLRSCQDKRDRTRLTVLSRLNRLESQSIKMDSKLDRIL 2041
            KS   K R SR      R  L    LN   + N+ + R  Q  IYNFLE P  +   +YH  +F  V +CL+LSVLSTI  Y  +A   L + E+V++ +F  EY +R+WSAGCRS+Y  +RGRI+FA++P  ++D+VV+LAS VVL  GS  Q  A SA RG+RF QILRM+ +DR+GG+W+LL SVV+ HRQEL TT+YIGFLGLIFSS+ +YL E   N+  N              +YADALWWGVIT+ T+GYGD VP+TW+GKIIA+  +V  ISFFALPAGILGSGFALKVQQ QRQKH  R+   AATLIQCLWRCYA  P+S   +TWKI+              ++  +  R + F    R +S KR  RR   SI    PS         SS       +TS  N        ++   S +   E    N I     ++  FR+L+ +  S +    +S  A R R     ++ ++++  +D     ++   +LTE  K  IR +R+++FF+A ++F++A +PYDV+DV+EQYS GH++M+ RIK LQ R+D  +G+   +  Q+    T++++ +R+ ++E Q   +++KLD ++
Sbjct:   48 KSSYFKERHSRH-----RTSLHGKALNFRANRNDARYRRLQAKIYNFLERPKTYSSIIYHILIFASVFMCLMLSVLSTIAKYDHIAGEALLYTELVMLFWFFTEYCLRMWSAGCRSRYQSWRGRIQFAKRPFCLVDVVVILASVVVLVIGSDRQKIAASAFRGLRFFQILRMIRMDRRGGSWKLLASVVWAHRQELFTTVYIGFLGLIFSSFLIYLVEKDKNQKIN--------------TYADALWWGVITLCTVGYGDIVPETWIGKIIAAFCAVAGISFFALPAGILGSGFALKVQQHQRQKHLIRRRVPAATLIQCLWRCYAADPNSTSGATWKIH----------MKPLRSPPNSDRLTRF---GRFSSIKR--RREKGSILHSHPSN--------SSLYRRNAIETSVPNQVTPSCEENEFPASNDVYNEEFLENSINSSRSMKKRFRALAQSMKSHMNINPSSIEASR-RSSNFVMAIEKESAVNDE----IQFITQLTEADKNVIRAVRKIKFFVARKKFREALRPYDVKDVMEQYSAGHVDMLARIKNLQSRLDLIVGQHGSKDNQNY--ETKISLTTRIIKIEKQVESIETKLDLLI 605