cilia- and flagella-associated protein 161

Overview
Namecilia- and flagella-associated protein 161
Smed IDSMED30033791
Length (bp)1058
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of cilia- and flagella-associated protein 161 (SMED30033791) t-SNE clustered cells

Violin plots show distribution of expression levels for cilia- and flagella-associated protein 161 (SMED30033791) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of cilia- and flagella-associated protein 161 (SMED30033791) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for cilia- and flagella-associated protein 161 (SMED30033791) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033791

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30033791h1SMcG0018228 SmedASXL_019421SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30033791h1SMcG0018228 Contig39684newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033791h1SMcG0018228 Contig39684uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033791h1SMcG0018228 Contig15502uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30033791h1SMcG0018228 Contig15502newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30033791h1SMcG0018228 dd_Smed_v4_8229_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30033791h1SMcG0018228 dd_Smed_v4_8229_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30033791h1SMcG0018228 dd_Smed_v4_8229_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30033791h1SMcG0018228 dd_Smed_v4_8229_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30033791h1SMcG0018228 dd_Smed_v4_8229_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30033791h1SMcG0018228 dd_Smed_v4_8229_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30033791h1SMcG0018228 dd_Smed_v6_8229_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30033791h1SMcG0018228 dd_Smed_v4_8229_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Human
Match: CFAP161 (cilia and flagella associated protein 161 [Source:HGNC Symbol;Acc:HGNC:26782])

HSP 1 Score: 126.331 bits (316), Expect = 3.735e-33
Identity = 85/275 (30.91%), Postives = 136/275 (49.45%), Query Frame = 2 
Query:  128 TYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQK--KDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQI---CSCNEEKYYLCCDTIQLSETKHKSRHFQVVMS-LFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGASDQTD 934
             Y   V +GNW EDV L++EL KDFL++++KG LL Q+ +++       + LS    G++ +GD++ L+N   DP      +A       +++ + P+  Q   KD+      ++A Q   P  RN F I+SV     GQ + YGQ F +      + +  YL  D   L ++  +S   +V ++    H N  W+A F  PQ+RLE E   +P    +++ H  TN  LA  +     T FG E E+   TYL+ H+ E   N+W+    +  D
Sbjct:    5 VYGPGVRIGNWNEDVYLEEELMKDFLEKRDKGKLLIQRSRRLKQNLLRPMQLSVTEDGYIHYGDKVMLVNP-DDPDT----EADVFLRGDLSLCMTPDEIQSHLKDELEVPCGLSAVQAKTPIGRNTFIILSVHRDATGQVLRYGQDFCLGITGGFDNKMLYLSSDHRTLLKSSKRSWLQEVYLTDEVSHVNC-WQAAFPDPQLRLEYEGFPVPANAKILINHCHTNRGLAAHRHLFLSTYFGKEAEVVAHTYLDSHRVEKPRNHWMLVTGNPRD 273
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Fly
Match: CG34457 (gene:FBgn0085486 transcript:FBtr0345621)

HSP 1 Score: 83.5741 bits (205), Expect = 8.042e-18
Identity = 72/299 (24.08%), Postives = 134/299 (44.82%), Query Frame = 2 
Query:  107 EMNSNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKA-VPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPN-GQPVVYGQPFQI-CSCNEEKYYLC------CDT---IQLSETKHKSRHFQVVMSLFDHFN------------THWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGASDQT 931
            +M+S    +  SV +GNW E+  L+++   +F  ++++G LL ++ + +      ++ L+      + FG  +QL+     PI I ++          +++ +   V +K    +    ++ + + +P  RN F+IVS DG    G+ + YGQ FQ+ C  +E    +       C+    +  +   HK+    + + L                 T+W     +P+ R E+E  +IP    +++ H  TN  LA E      TLFG E+ +S Q Y N ++ E+  N W+     QT
Sbjct:    7 DMDSISARFQPSVRIGNWVEENCLEEDKIVNFKKQRDRGELLVEKARTLYDNFHKEIVLA-APKQTIIFGAIVQLM-----PIHINISDMDTTDLNAALSVVINEKVVRKSQSINEDCELSVAPSKRPCVRNSFKIVSGDGRDRTGENIKYGQRFQLQCMASEHDPIVLYSGPKRCNLQQGVHATYLSHKNGELNLNLGLVHRSKLSCPDNDIPIAYTNWFCRHVNPKQRFESEGEDIPSNSPLVIVHATTNRNLAAENVLIQ-TLFGPEFLVSVQNYRNIYRHEIWKNVWMISNGHQT 298
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Fly
Match: CG34457 (gene:FBgn0085486 transcript:FBtr0112763)

HSP 1 Score: 83.5741 bits (205), Expect = 8.042e-18
Identity = 72/299 (24.08%), Postives = 134/299 (44.82%), Query Frame = 2 
Query:  107 EMNSNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKA-VPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPN-GQPVVYGQPFQI-CSCNEEKYYLC------CDT---IQLSETKHKSRHFQVVMSLFDHFN------------THWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGASDQT 931
            +M+S    +  SV +GNW E+  L+++   +F  ++++G LL ++ + +      ++ L+      + FG  +QL+     PI I ++          +++ +   V +K    +    ++ + + +P  RN F+IVS DG    G+ + YGQ FQ+ C  +E    +       C+    +  +   HK+    + + L                 T+W     +P+ R E+E  +IP    +++ H  TN  LA E      TLFG E+ +S Q Y N ++ E+  N W+     QT
Sbjct:    7 DMDSISARFQPSVRIGNWVEENCLEEDKIVNFKKQRDRGELLVEKARTLYDNFHKEIVLA-APKQTIIFGAIVQLM-----PIHINISDMDTTDLNAALSVVINEKVVRKSQSINEDCELSVAPSKRPCVRNSFKIVSGDGRDRTGENIKYGQRFQLQCMASEHDPIVLYSGPKRCNLQQGVHATYLSHKNGELNLNLGLVHRSKLSCPDNDIPIAYTNWFCRHVNPKQRFESEGEDIPSNSPLVIVHATTNRNLAAENVLIQ-TLFGPEFLVSVQNYRNIYRHEIWKNVWMISNGHQT 298
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Fly
Match: CG15498 (gene:FBgn0038892 transcript:FBtr0084122)

HSP 1 Score: 76.6406 bits (187), Expect = 1.322e-15
Identity = 77/289 (26.64%), Postives = 127/289 (43.94%), Query Frame = 2 
Query:  131 YNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQL-NKAVPRKPTVVNISVPPNVFQKKDDTSN-IINVTASQNLKPNSRNIFQIVSVDGTPN-----GQPVVYGQPFQICSCN--EEKYYLCCDTIQLSETKHKSRHF--------QVVMSLFDHFN-----------THWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIF 913
            Y   V VGNW E    ++    +   R+E G LL  + + +         L P     L FG  +Q+      P+ I +  + V  +  V+++ +      +   T N + ++T + + +P  RN F+IVS    PN     GQ + YG+ F++ +    +E  Y+     +L+ +    + F         + + L  H N           TH+      P +R E+E   IPV   +++ H  TN  LA+E   A+ TLFG E+++S QTY N +K E   N W F
Sbjct:    2 YGPGVKVGNWLETALSEEMRMSEMKKRRESGNLLLDRTRAVYDRFYQGTVLGP-PQDVLAFGVVVQI-----RPVKIGVCRQQVSDQNLVLSVVITQEGLHRNCKTINEMCDLTVAPSPRPALRNSFRIVS----PNEDDRTGQYLAYGEKFRLQALEPADEPMYVFSGPKRLNLSLPVEKAFFTTKNGEVTLPLGLVSHKNCGPSARVPTSHTHFFCAHKDPDLRFESEGKTIPVHNPLVIVHAVTNRNLAVENVLAN-TLFGPEFQVSVQTYKNVYKRETWKNLWKF 279
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Zebrafish
Match: cfap161 (cilia and flagella associated protein 161 [Source:NCBI gene;Acc:550471])

HSP 1 Score: 141.739 bits (356), Expect = 3.988e-39
Identity = 91/276 (32.97%), Postives = 138/276 (50.00%), Query Frame = 2 
Query:  125 RTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTS------NIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCN--EEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFN--THWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGAS 922
            RTYN  V VGNW EDV L++E  K+F+ +K++G L  Q+   +       V LS    G L FGD + L+N G           + R P V++I    +       T+        + V  + ++ P  RN F I+SVDG+ +G+ V Y Q F + +      + +L  D     +   KSR  +  +SL + F+    WK  ++ PQ RLENE   + V   V++ H KTN  LA   +    + FG EYE++  T+L+ HKAE D N+W+F  +
Sbjct:    5 RTYNPRVRVGNWKEDVTLEEETLKEFILQKDRGELTVQKEGALKQSILKPVSLSVSQDGFLHFGDTVMLVNCGD-------GGHMQRSPCVLSIIADSSNVTSHSQTNTGPHLLGPLQVGGAHSMDPCVRNTFIIISVDGSSDGEVVRYDQSFALKTTGGFAGELFLASDHKSFQKCAKKSRLQE--LSLVEEFDFLCWWKVLYFDPQDRLENEGYPVQVNNKVLISHCKTNQCLAALSNHILWSQFGKEYELTAHTFLDSHKAEQDNNHWLFSTA 271
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Xenopus
Match: med31 (mediator complex subunit 31 [Source:Xenbase;Acc:XB-GENE-951034])

HSP 1 Score: 146.362 bits (368), Expect = 7.987e-41
Identity = 91/264 (34.47%), Postives = 137/264 (51.89%), Query Frame = 2 
Query:  125 RTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCNEEKYYLCCDTIQLSETKHKSRHFQVVMSLFDH--FNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWI 910
            RT+  SV +GNW EDVAL++++ KD+L++K+KG LL Q+   +         LS    G L FGD + LLN  +   ++  N +       ++++   N    K        V+ S NL+P  RN F I SVDG+  G+PV YGQ F + +      +L   + Q +  K   + +   +SL D   +   W   +  PQ+RLENE   +P    +++ H KTN  LA+ +     T FG E EI+  T+LN HKAE + N+WI
Sbjct:    4 RTFCPSVRLGNWNEDVALEEDILKDYLEKKDKGELLIQKTSNLKKNILKKTELSISQDGCLHFGDVVMLLNPENSEQSLS-NTSPTNGNYALSVNPNENAVYSKTHLEAPCGVSGSTNLEPTVRNAFIITSVDGSDVGEPVHYGQNFALRTTEGFMNHLHLTSDQKTFLKSSKKSYLQEVSLTDQLSYQNCWNFIYLDPQLRLENEGFPVPANTKLLIVHSKTNQCLAVLRKQVLWTFFGKECEITAHTFLNGHKAEENENHWI 266
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Xenopus
Match: med31 (mediator complex subunit 31 [Source:Xenbase;Acc:XB-GENE-951034])

HSP 1 Score: 143.28 bits (360), Expect = 1.004e-39
Identity = 90/268 (33.58%), Postives = 136/268 (50.75%), Query Frame = 2 
Query:  125 RTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCN------EEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWI 910
            RT+  SV +GNW EDVAL++++ KD+L++K+KG LL Q+   +         LS    G L FGD + LLN  +   ++  N +       ++++   N    K        V+ S NL+P  RN F I SVDG+  G+PV YGQ F + +           +Y   D     ++  KS   +V ++    +   W   +  PQ+RLENE   +P    +++ H KTN  LA+ +     T FG E EI+  T+LN HKAE + N+WI
Sbjct:    4 RTFCPSVRLGNWNEDVALEEDILKDYLEKKDKGELLIQKTSNLKKNILKKTELSISQDGCLHFGDVVMLLNPENSEQSLS-NTSPTNGNYALSVNPNENAVYSKTHLEAPCGVSGSTNLEPTVRNAFIITSVDGSDVGEPVHYGQNFALRTTEGFMNHVSNTFYNISDQKTFLKSSKKSYLQEVSLTDQLSYQNCWNFIYLDPQLRLENEGFPVPANTKLLIVHSKTNQCLAVLRKQVLWTFFGKECEITAHTFLNGHKAEENENHWI 270
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Mouse
Match: Cfap161 (cilia and flagella associated protein 161 [Source:MGI Symbol;Acc:MGI:1922806])

HSP 1 Score: 125.561 bits (314), Expect = 6.134e-33
Identity = 89/269 (33.09%), Postives = 135/269 (50.19%), Query Frame = 2 
Query:  128 TYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPN---GQPVVYGQPF--QICSCNEEKY-YLCCDTIQLSETKHKSRHFQVVMS-LFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIF 913
             Y   V +GNW EDV L++E  + FL+++EKG LL Q+ +++       + LS    G++ +GD++ ++N   D +  +      R    + +S      Q  DD      V+A Q + P  RN F I+S DG  +   GQ VVYGQ F   I +  E K  YL  D   L ++  KS   +V ++    H N  W+A F  PQ+RLE E   +   + +++ H  TN ALA+ ++    T FG E E+   TYL+ HK E   N W+ 
Sbjct:    5 VYGPGVRMGNWNEDVYLEEERMRHFLEKREKGELLIQRNRRVKKNILRPMQLSVSEDGYVHYGDKVIIVNP--DQVLGEEAGKFMRGDLSLCMSPDEVKAQLSDDLEIPCGVSAVQTIAPMGRNTFTILS-DGANSCEMGQVVVYGQNFCLGIAAGLEGKMLYLTSDHRTLLKSSLKSGLQEVTLTDEVTHLNC-WQAAFLDPQLRLEYEGFPVRANEKIVIYHRHTNRALAVHRNLFLRTYFGKEMEVVAHTYLDSHKVEKPKNQWML 269
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Mouse
Match: Cfap161 (cilia and flagella associated protein 161 [Source:MGI Symbol;Acc:MGI:1922806])

HSP 1 Score: 100.138 bits (248), Expect = 5.356e-24
Identity = 76/237 (32.07%), Postives = 119/237 (50.21%), Query Frame = 2 
Query:  128 TYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPN---GQPVVYGQPF--QICSCNEEKY-YLCCDTIQLSETKHKSRHFQVVMS-LFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDF 817
             Y   V +GNW EDV L++E  + FL+++EKG LL Q+ +++       + LS    G++ +GD++ ++N   D +  +      R    + +S      Q  DD      V+A Q + P  RN F I+S DG  +   GQ VVYGQ F   I +  E K  YL  D   L ++  KS   +V ++    H N  W+A F  PQ+RLE E   +   + +++ H  TN ALA+ ++ 
Sbjct:    5 VYGPGVRMGNWNEDVYLEEERMRHFLEKREKGELLIQRNRRVKKNILRPMQLSVSEDGYVHYGDKVIIVN--PDQVLGEEAGKFMRGDLSLCMSPDEVKAQLSDDLEIPCGVSAVQTIAPMGRNTFTILS-DGANSCEMGQVVVYGQNFCLGIAAGLEGKMLYLTSDHRTLLKSSLKSGLQEVTLTDEVTHLNC-WQAAFLDPQLRLEYEGFPVRANEKIVIYHRHTNRALAVHRNL 237
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Mouse
Match: Cfap161 (cilia and flagella associated protein 161 [Source:MGI Symbol;Acc:MGI:1922806])

HSP 1 Score: 51.6026 bits (122), Expect = 1.361e-7
Identity = 39/127 (30.71%), Postives = 63/127 (49.61%), Query Frame = 2 
Query:  194 KDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPN---GQPVVYGQPF 565
            + FL+++EKG LL Q+ +++       + LS    G++ +GD++ ++N   D +  +      R    + +S      Q  DD      V+A Q + P  RN F I+S DG  +   GQ VVYGQ F
Sbjct:    2 RHFLEKREKGELLIQRNRRVKKNILRPMQLSVSEDGYVHYGDKVIIVNP--DQVLGEEAGKFMRGDLSLCMSPDEVKAQLSDDLEIPCGVSAVQTIAPMGRNTFTILS-DGANSCEMGQVVVYGQNF 125
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. UniProt/SwissProt
Match: sp|Q568D2|CF161_DANRE (Cilia- and flagella-associated protein 161 OS=Danio rerio OX=7955 GN=cfap161 PE=2 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 1.146e-38
Identity = 91/276 (32.97%), Postives = 139/276 (50.36%), Query Frame = 2 
Query:  125 RTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTS------NIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCN--EEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFN--THWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGAS 922
            RTYN  V VGNW EDV L++E +K+F+ +K++G L  Q+   +       V LS    G L FGD + L+N G           + R P V++I    +       T+        + V  + ++ P  RN F I+SVDG+ +G+ V Y Q F + +      + +L  D     +   KSR  +  +SL + F+    WK  ++ PQ RLENE   + V   V++ H KTN  LA   +    + FG EYE++  T+L+ HKAE D N+W+F  +
Sbjct:    5 RTYNPRVRVGNWKEDVTLEEETSKEFILQKDRGELTVQKEGALKQSILKPVSLSVSQDGFLHFGDTVMLVNCGD-------GGHMQRSPCVLSIIADSSNVTSHSQTNTGPHLLGPLQVGGAHSMDPCVRNTFIIISVDGSSDGEVVRYDQSFALKTTGGFAGELFLASDHKSFQKCAKKSRLQE--LSLVEEFDFLCWWKVLYFDPQDRLENEGYPVQVNNKVLISHCKTNQCLAALSNHILWSQFGKEYELTAHTFLDSHKAEQDNNHWLFSTA 271
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. UniProt/SwissProt
Match: sp|Q6P656|CF161_HUMAN (Cilia- and flagella-associated protein 161 OS=Homo sapiens OX=9606 GN=CFAP161 PE=1 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 1.794e-32
Identity = 85/275 (30.91%), Postives = 136/275 (49.45%), Query Frame = 2 
Query:  128 TYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQK--KDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQI---CSCNEEKYYLCCDTIQLSETKHKSRHFQVVMS-LFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGASDQTD 934
             Y   V +GNW EDV L++EL KDFL++++KG LL Q+ +++       + LS    G++ +GD++ L+N   DP      +A       +++ + P+  Q   KD+      ++A Q   P  RN F I+SV     GQ + YGQ F +      + +  YL  D   L ++  +S   +V ++    H N  W+A F  PQ+RLE E   +P    +++ H  TN  LA  +     T FG E E+   TYL+ H+ E   N+W+    +  D
Sbjct:    5 VYGPGVRIGNWNEDVYLEEELMKDFLEKRDKGKLLIQRSRRLKQNLLRPMQLSVTEDGYIHYGDKVMLVNP-DDPDT----EADVFLRGDLSLCMTPDEIQSHLKDELEVPCGLSAVQAKTPIGRNTFIILSVHRDATGQVLRYGQDFCLGITGGFDNKMLYLSSDHRTLLKSSKRSWLQEVYLTDEVSHVNC-WQAAFPDPQLRLEYEGFPVPANAKILINHCHTNRGLAAHRHLFLSTYFGKEAEVVAHTYLDSHRVEKPRNHWMLVTGNPRD 273
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. UniProt/SwissProt
Match: sp|Q6P8Y0|CF161_MOUSE (Cilia- and flagella-associated protein 161 OS=Mus musculus OX=10090 GN=Cfap161 PE=1 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 4.290e-32
Identity = 89/269 (33.09%), Postives = 135/269 (50.19%), Query Frame = 2 
Query:  128 TYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPN---GQPVVYGQPF--QICSCNEEKY-YLCCDTIQLSETKHKSRHFQVVMS-LFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIF 913
             Y   V +GNW EDV L++E  + FL+++EKG LL Q+ +++       + LS    G++ +GD++ ++N   D +  +      R    + +S      Q  DD      V+A Q + P  RN F I+S DG  +   GQ VVYGQ F   I +  E K  YL  D   L ++  KS   +V ++    H N  W+A F  PQ+RLE E   +   + +++ H  TN ALA+ ++    T FG E E+   TYL+ HK E   N W+ 
Sbjct:    5 VYGPGVRMGNWNEDVYLEEERMRHFLEKREKGELLIQRNRRVKKNILRPMQLSVSEDGYVHYGDKVIIVNP--DQVLGEEAGKFMRGDLSLCMSPDEVKAQLSDDLEIPCGVSAVQTIAPMGRNTFTILS-DGANSCEMGQVVVYGQNFCLGIAAGLEGKMLYLTSDHRTLLKSSLKSGLQEVTLTDEVTHLNC-WQAAFLDPQLRLEYEGFPVRANEKIVIYHRHTNRALAVHRNLFLRTYFGKEMEVVAHTYLDSHKVEKPKNQWML 269
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. TrEMBL
Match: A0A1I8GTE2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012001g1 PE=4 SV=1)

HSP 1 Score: 220.705 bits (561), Expect = 2.495e-66
Identity = 112/280 (40.00%), Postives = 167/280 (59.64%), Query Frame = 2 
Query:  116 SNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKIL---------GGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDT-SNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCNE--EKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGA 919
            ++ RTYN SV VGNWFED  L+++  K+FL++KE+G LL+Q++  +             DS   LS    G L FGDR+QL N G+D   ++L +  PR P+V+++S+   V         +    +A+Q+ +   RN+F IVSVDGTP G+PV + QPFQ+ + +   +  +L  D ++  +T  K     V  +    F THW+AE+++PQ+R+E E   IPVG+ +IL+H KTN  LA+E  F    L G E+++S QTY  DHKAE D N+W+F A
Sbjct:    2 AHARTYNPSVRVGNWFEDCQLEEDTIKNFLEKKERGELLSQKVGNLYKSVASNSSSTSADSGAALSTSQDGLLHFGDRVQLRNPGADAALVRLGRCQPRCPSVLSVSIGEEVLSSPAGALPDPSPASAAQSCQAMGRNVFTIVSVDGTPEGKPVTFNQPFQLATHSSLGKPMFLSSDRVKFGDTPRKHGKQAVQFTAESSFLTHWRAEYFNPQLRMEYEGAPIPVGEPLILKHAKTNQGLAVEDKFVIRGLMGTEFDVSSQTYFTDHKAETDANHWVFAA 281
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. TrEMBL
Match: A0A1I8FZ29 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 221.09 bits (562), Expect = 3.198e-66
Identity = 112/280 (40.00%), Postives = 167/280 (59.64%), Query Frame = 2 
Query:  116 SNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKIL---------GGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDT-SNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCNE--EKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGA 919
            ++ RTYN SV VGNWFED  L+++  K+FL++KE+G LL+Q++  +             DS   LS    G L FGDR+QL N G+D   ++L +  PR P+V+++S+   V         +    +A+Q+ +   RN+F IVSVDGTP G+PV + QPFQ+ + +   +  +L  D ++  +T  K     V  +    F THW+AE+++PQ+R+E E   IPVG+ +IL+H KTN  LA+E  F    L G E+++S QTY  DHKAE D N+W+F A
Sbjct:    2 AHARTYNPSVRVGNWFEDCQLEEDTIKNFLEKKERGELLSQKVGNLYKSVASNSSSTSADSGAALSTSQDGLLHFGDRVQLRNPGADAALVRLGRCQPRCPSVLSVSIGEEVLSSPAGALPDPSPASAAQSCQAMGRNVFTIVSVDGTPEGKPVTFNQPFQLATHSSLGKPMFLSSDRVKFGDTPRKHGKQAVQFTAESSFLTHWRAEYFNPQLRMEYEGAPIPVGEPLILKHAKTNQGLAVEDKFVIRGLMGTEFDVSSQTYFTDHKAETDANHWVFAA 281
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. TrEMBL
Match: F6SY22 (Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2)

HSP 1 Score: 178.718 bits (452), Expect = 7.038e-50
Identity = 102/277 (36.82%), Postives = 154/277 (55.60%), Query Frame = 2 
Query:  125 RTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKP-TVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICS----CNEEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFN--THWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGASDQTD 934
            RTYN SV VGNW ED+ L+++L KDFL +KEKG LL Q+   ++        L+  + G + FGD + L+N G + + + L +  P +P T ++I++  +            NV+AS+ L P++RN F I SVDG+ NG P+ +GQPF I +       E   L  D  + + +  KSR  Q ++ L D  N  + W+   YHPQ RLE E   +P    +++ H KT  AL+   +    T FG E+E+S  T L+ HKAE D N+W+F + + +D
Sbjct:    4 RTYNPSVRVGNWNEDICLEEDLLKDFLGKKEKGELLIQKSHNLMHNILKKSELTVTTDGFVHFGDVVMLVNPGQETVPLSLQQIEPPRPATSLSINIDEHKMHTACQVEGPCNVSASKMLNPSARNSFVITSVDGSENGSPLKFGQPFAISTTGGYAGNEMLKLFSDHARFNLSAKKSR--QQIVQLVDEVNYLSTWQVLAYHPQHRLEFEGRPVPGNCKIVVSHNKTGQALSTPDECGLKTPFGREFEVSAHTVLDTHKAEKDNNHWVFVSGNPSD 278
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. TrEMBL
Match: A0A0P7WX71 (Uncharacterized protein OS=Scleropages formosus OX=113540 GN=Z043_115209 PE=4 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 2.240e-49
Identity = 97/265 (36.60%), Postives = 147/265 (55.47%), Query Frame = 2 
Query:  125 RTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCNE--EKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIF 913
            RTY+ +V VGNW EDV +++E+ KDFLD++ +G L  Q+   +       V LS  + G L+FGD + L+N G+D    Q      R P  V +SV P   Q +        +T +Q+L+P  R  F + SVDGTP G+P+ Y Q F + +      + YL  D        ++SR  QV ++  + F T W+  +  PQ RLENE   +P    V++ H KTN  LA+  + +  T++G EYE++  T+L+ HKAE ++N+WIF
Sbjct:   31 RTYSPAVRVGNWCEDVFMEEEMLKDFLDKRNRGELTMQKTDFVKENVLRKVDLSVTTDGWLRFGDVVMLVNPGTDRGDWQST----RDPVAVCMSVDPGTVQSRLSVQAPCPLTGTQDLEPCVRTAFVVTSVDGTPVGEPLRYSQSFALRTTQGFGGQLYLVSDHRTFLRCANRSRLQQVSLTDEESFLTWWQVVYLDPQERLENERLPVPANTKVLVVHCKTNQCLAVLGNHSMWTIYGKEYEVTAHTFLDSHKAEREMNHWIF 291
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. TrEMBL
Match: F6SY27 (Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2)

HSP 1 Score: 176.792 bits (447), Expect = 2.566e-49
Identity = 101/275 (36.73%), Postives = 152/275 (55.27%), Query Frame = 2 
Query:  125 RTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKP-TVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCN--EEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFN--THWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGASDQTD 934
            RTYN SV VGNW ED+ L+++L KDFL +KEKG LL Q+   ++        L+  + G + FGD + L+N G + + + L +  P +P T ++I++  +            NV+AS+ L P++RN F I SVDG+ NG P+ +GQPF I +         L  D  + + +  KSR  Q ++ L D  N  + W+   YHPQ RLE E   +P   +++L H KT   L +       T FG E+E+S  T L+ HKAE D N+W+F + + +D
Sbjct:    4 RTYNPSVRVGNWNEDICLEEDLLKDFLGKKEKGELLIQKSHNLMHNILKKSELTVTTDGFVHFGDVVMLVNPGQETVPLSLQQIEPPRPATSLSINIDEHKMHTACQVEGPCNVSASKMLNPSARNSFVITSVDGSENGSPLKFGQPFAISTTGGYAGNLKLFSDHARFNLSAKKSR--QQIVQLVDEVNYLSTWQVLAYHPQHRLEFEGRPVPANTMLLLHHNKTGEKLIVLDKHTLRTPFGREFEVSAHTVLDTHKAEKDNNHWVFVSGNPSD 276
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Cavefish
Match: cfap161 (cilia and flagella associated protein 161 [Source:NCBI gene;Acc:103028325])

HSP 1 Score: 137.887 bits (346), Expect = 9.637e-38
Identity = 90/280 (32.14%), Postives = 135/280 (48.21%), Query Frame = 2 
Query:  116 SNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGS------DPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTS--NIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQI--CSCNEEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGASD 925
            S+ RTY +SV VGNW EDV L+ +  KDFL R+++G L  Q+   +       V LS    G L+FGD + L+N+G       DP ++ +         V ++S   +  Q   +T       V  +  L P  RN   I SVDGT  G+ + Y Q F +   +    + Y+  D     +    SR  +V +     F   W+  ++ PQ RLE+E   +     V++ H KTN  LA   +    T FG EYE+   T+L+ HKAE + N+W+F  +D
Sbjct:    2 SSARTYRASVRVGNWMEDVTLEKDSLKDFLYRRDRGELTVQKTDLLKQTLLKPVSLSVSRDGFLRFGDTVMLVNSGGTDHDPCDPCSLSI---------VADLSNMKSHPQTSSNTGLYGPFQVGGASGLTPCVRNALIITSVDGTAEGEVLRYEQSFALRTTAAFSGELYMASDHRTFQKCAKSSRLQEVSLVEQADFLCWWRVVYFDPQERLEHEGYPVQGNTKVLITHCKTNQCLAALANHEVWTPFGKEYELVAHTFLDSHKAEQNSNHWLFVTAD 272
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Nematostella
Match: EDO42146 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2G6])

HSP 1 Score: 140.198 bits (352), Expect = 2.840e-39
Identity = 83/281 (29.54%), Postives = 134/281 (47.69%), Query Frame = 2 
Query:  125 RTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCNE--EKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIF------GASDQTDIEK 943
            RTYN SVL+GNW ED+ L+++  KDFLD+KEKG LL Q+   +LG                                   + K  P    ++  ++  +  +         +++AS++L+P  RN F IVS +    GQ + YGQPF + +         +  D +  ++   KSR  + +++    F  HW    + PQ RLEN+   +P  + ++  H KTN  LA   +F+  T FG E E++  T L+ H+AE   N+W+        A++Q +IE+
Sbjct:    4 RTYNPSVLIGNWNEDICLEEDKLKDFLDKKEKGELLIQKASNLLGN----------------------------------ILKKNPASEVLLTANMSESKMRDAQSLGGPCDISASKSLQPCVRNTFMIVSPELYQEGQVLRYGQPFMLSTLPGVGGSLRMHSDRVTFNKAAKKSRKQECLLTDNSSFTAHWNCLCFDPQQRLENDGMPVPANQRILFNHCKTNQNLACMSEFSFRTPFGREMEVAAHTSLDSHRAETPANHWVILTRTVEDAAEQHEIER 250
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Nematostella
Match: EDO26000 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TD55])

HSP 1 Score: 65.0846 bits (157), Expect = 1.684e-12
Identity = 61/213 (28.64%), Postives = 95/213 (44.60%), Query Frame = 2 
Query:  194 KDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYG-QPFQICSCNEEKYYLCCDTI--QLSETKHKSRHFQVVMSLF-DHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFA 820
            KDFLD+KEKG LL Q+   +LG       LS    G+L FGD + + N  S+ + +  N +  +     ++  P              +++AS++L+P  RN F IV        Q ++ G + F+         +L  D I   L  +  K R   VV +LF            + PQ RLEN+   +P  + ++  H KTN  LA   +F+
Sbjct:    5 KDFLDKKEKGELLIQKASNLLGNILKKTELSVSHDGYLHFGDIVCVYNPASE-VLLTANMSESKMRDAQSLGGP-------------CDISASKSLQPCVRNTFMIVRF----VRQSLLQGFKDFE--GRGGSLTHLADDFILGSLHTSSFKKRQNLVVANLFLCSLIVFRNCLCFDPQQRLENDGMPVPANQRILFNHCKTNQNLACMSEFS 197
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Medaka
Match: cfap161 (cilia and flagella associated protein 161 [Source:NCBI gene;Acc:101173542])

HSP 1 Score: 143.665 bits (361), Expect = 3.410e-40
Identity = 92/272 (33.82%), Postives = 139/272 (51.10%), Query Frame = 2 
Query:  125 RTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGS---DPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCN--EEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGASD 925
            RTY S V VGNW ED  L+ +  K++L++KEKG L  Q++  +       V+LS  + G L FGD + L+N G+   D  A+ ++  V    TV + S+P +             VTA + ++P +R  F + SVDG P G  + + Q F + + +   +  YL  D     +   KS   +V +     F + WK     P  RLE+E   +P    V++ H KTN ALA+  D A  T FG EYE++  T+L+ HK E + N+W+   SD
Sbjct:    5 RTYRSKVKVGNWTEDELLQKDAMKEYLEKKEKGELYVQKIDLLRQNMLKPVNLSVTNDGDLHFGDVVMLVNVGAGNRDRSAVSIDADVNSLMTVPSPSIPVSC-----------GVTAGRTIQPCTRTAFIVTSVDGNPEGSVLHFEQHFALRTLSGFAKGLYLTSDMRSFQKCAKKSHLQEVYLDESKCFLSCWKIVHLDPLERLEHEGLPVPANVKVLILHCKTNQALAVLGDQALWTTFGEEYEVTTHTFLDCHKLEQENNHWVLCTSD 265
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Planmine SMEST
Match: SMESG000028972.1 (SMESG000028972.1)

HSP 1 Score: 592.038 bits (1525), Expect = 0.000e+0
Identity = 283/285 (99.30%), Postives = 283/285 (99.30%), Query Frame = 2 
Query:  110 MNSNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQPFQICSCNEEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIFGASDQTDIEKCSKEHAD 964
            MNSNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQI SVDGTPNGQPVVYGQPFQICSCNEEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEIS QTYLNDHKAEMDVNYWIFGASDQTDIEKCSKEHAD
Sbjct:    1 MNSNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIFSVDGTPNGQPVVYGQPFQICSCNEEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISTQTYLNDHKAEMDVNYWIFGASDQTDIEKCSKEHAD 285
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Planmine SMEST
Match: SMESG000049898.1 (SMESG000049898.1)

HSP 1 Score: 95.9005 bits (237), Expect = 7.776e-24
Identity = 47/136 (34.56%), Postives = 81/136 (59.56%), Query Frame = 2 
Query:  107 EMNSNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILGGTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNISVPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIV 514
            E+   K  YNS VL+ +WF++  L++E+ KDFL +++ G L+ Q++  +L         S  + G ++FGD+IQ++N GSDP  ++L +   R P+V++I     +   +++  +    TAS  L P SRN+F+IV
Sbjct:    4 EIPQIKNQYNSKVLIDSWFDNRILEEEIIKDFLAKRDSGQLMIQKMGSLLKKMSQAASPSTIADGFVRFGDQIQIINIGSDPNMVRLQRITSRPPSVLSIDAADEMLYFRNELPDPSTCTASFKLDPLSRNVFEIV 139
[Close]
BLAST of cilia- and flagella-associated protein 161 vs. Planmine SMEST
Match: SMESG000049902.1 (SMESG000049902.1)

HSP 1 Score: 81.6481 bits (200), Expect = 1.037e-18
Identity = 47/131 (35.88%), Postives = 69/131 (52.67%), Query Frame = 2 
Query:  596 YLCCDTIQLSETKHKSRHFQVV----MSLFDHFNTHWKAEFYHPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISGQTYLNDHKAEMDVNYWIF-------GASDQTDIEKCSKE 955
            Y+  D      T  +S+H +V     +S   HFN     +   P+ RL++E   I   + ++++H K+N ALA+E  F   T FG E+E+S  T+LNDH+ EMD N+WIF       G  D  D  KC +E
Sbjct:    2 YISSDNCAFVTTAKQSKHQEVCCIGGLSYLSHFNV----QHADPRKRLQHEGCPIKASEKIVIKHGKSNQALAVESKFYEKTFFGYEHEVSAFTFLNDHRVEMDYNHWIFKGKLLTGGNVDLFDTTKCHEE 128
The following BLAST results are available for this feature:
BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CFAP1613.735e-3330.91cilia and flagella associated protein 161 [Source:... [more]
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CG344578.042e-1824.08gene:FBgn0085486 transcript:FBtr0345621[more]
CG344578.042e-1824.08gene:FBgn0085486 transcript:FBtr0112763[more]
CG154981.322e-1526.64gene:FBgn0038892 transcript:FBtr0084122[more]
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cfap1613.988e-3932.97cilia and flagella associated protein 161 [Source:... [more]
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
med317.987e-4134.47mediator complex subunit 31 [Source:Xenbase;Acc:XB... [more]
med311.004e-3933.58mediator complex subunit 31 [Source:Xenbase;Acc:XB... [more]
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Cfap1616.134e-3333.09cilia and flagella associated protein 161 [Source:... [more]
Cfap1615.356e-2432.07cilia and flagella associated protein 161 [Source:... [more]
Cfap1611.361e-730.71cilia and flagella associated protein 161 [Source:... [more]
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BLAST of cilia- and flagella-associated protein 161 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|Q568D2|CF161_DANRE1.146e-3832.97Cilia- and flagella-associated protein 161 OS=Dani... [more]
sp|Q6P656|CF161_HUMAN1.794e-3230.91Cilia- and flagella-associated protein 161 OS=Homo... [more]
sp|Q6P8Y0|CF161_MOUSE4.290e-3233.09Cilia- and flagella-associated protein 161 OS=Mus ... [more]
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BLAST of cilia- and flagella-associated protein 161 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8GTE22.495e-6640.00Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8FZ293.198e-6640.00Uncharacterized protein OS=Macrostomum lignano OX=... [more]
F6SY227.038e-5036.82Uncharacterized protein OS=Ciona intestinalis OX=7... [more]
A0A0P7WX712.240e-4936.60Uncharacterized protein OS=Scleropages formosus OX... [more]
F6SY272.566e-4936.73Uncharacterized protein OS=Ciona intestinalis OX=7... [more]
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cfap1619.637e-3832.14cilia and flagella associated protein 161 [Source:... [more]
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO421462.840e-3929.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO260001.684e-1228.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of cilia- and flagella-associated protein 161 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cfap1613.410e-4033.82cilia and flagella associated protein 161 [Source:... [more]
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BLAST of cilia- and flagella-associated protein 161 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000028972.10.000e+099.30SMESG000028972.1[more]
SMESG000049898.17.776e-2434.56SMESG000049898.1[more]
SMESG000049902.11.037e-1835.88SMESG000049902.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033791 ID=SMED30033791|Name=cilia- and flagella-associated protein 161|organism=Schmidtea mediterranea sexual|type=transcript|length=1058bp
AATCAAGCCAAACACTTTAATTTATAATTAAATTTTTCTTATGATATTGT
TTTAATATTCTAAATTGAAATTGCTATGTCGACTGAATTTGTTCATTTTT
GAAAGTGAAATGAATAGCAACAAACGTACTTATAACTCATCAGTTCTGGT
CGGAAATTGGTTTGAAGATGTTGCATTAAAAGATGAATTGACTAAAGACT
TTTTGGATCGCAAAGAAAAGGGATTGTTATTGACACAGCAGTTAAAGAAA
ATTTTGGGAGGCACCGATTCTGATGTTCATTTGTCACCTTGTTCAAGTGG
TCACCTTAAATTCGGTGATAGAATCCAATTATTGAATGCAGGCTCTGATC
CCATCGCTATTCAGCTCAATAAAGCTGTGCCTCGTAAGCCAACAGTAGTG
AACATTAGTGTCCCACCAAATGTGTTTCAAAAGAAAGATGATACCAGCAA
CATTATTAATGTAACTGCCTCTCAAAATCTGAAACCAAATTCAAGGAATA
TTTTTCAAATTGTCAGTGTCGATGGAACTCCAAATGGTCAACCTGTCGTT
TATGGACAACCATTCCAAATCTGTAGCTGCAATGAAGAAAAATATTATTT
ATGTTGCGACACGATTCAACTATCTGAAACTAAACACAAAAGCCGACATT
TTCAAGTTGTAATGAGCCTGTTTGATCACTTTAATACGCATTGGAAAGCG
GAATTTTATCATCCGCAAATGAGATTAGAAAATGAATTCACTGAAATTCC
GGTTGGAAAAGTTGTAATTCTAAGACATTTGAAAACCAATCATGCGCTGG
CCTTAGAGAAAGATTTCGCCTCATTAACCCTTTTCGGAAATGAATATGAA
ATCAGTGGTCAGACTTATCTAAATGATCACAAAGCCGAAATGGATGTCAA
TTATTGGATATTTGGAGCTTCAGATCAAACAGACATAGAAAAATGTTCCA
AGGAACATGCTGATTAATTTAAAAAATTGTGTTTACTTGATCTAATTTAT
AGACTGTGGTCATTTATGTAATTAAATAATATAATTACAAACGTCATTAT
CCTGTTTC
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protein sequence of SMED30033791-orf-1

>SMED30033791-orf-1 ID=SMED30033791-orf-1|Name=SMED30033791-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=286bp
MNSNKRTYNSSVLVGNWFEDVALKDELTKDFLDRKEKGLLLTQQLKKILG
GTDSDVHLSPCSSGHLKFGDRIQLLNAGSDPIAIQLNKAVPRKPTVVNIS
VPPNVFQKKDDTSNIINVTASQNLKPNSRNIFQIVSVDGTPNGQPVVYGQ
PFQICSCNEEKYYLCCDTIQLSETKHKSRHFQVVMSLFDHFNTHWKAEFY
HPQMRLENEFTEIPVGKVVILRHLKTNHALALEKDFASLTLFGNEYEISG
QTYLNDHKAEMDVNYWIFGASDQTDIEKCSKEHAD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: molecular function
TermDefinition
GO:0003674molecular_function
Vocabulary: cellular component
TermDefinition
GO:0031514motile cilium
Vocabulary: biological process
TermDefinition
GO:0060271cilium morphogenesis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:2.80.10.50coord: 110..283
e-value: 7.0E-9
score: 37.4
NoneNo IPR availablePANTHERPTHR24274FAMILY NOT NAMEDcoord: 4..278