Serine threonine-kinase 25
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033787 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of Serine threonine-kinase 25 vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 158.303 bits (399), Expect = 1.735e-42 Identity = 98/254 (38.58%), Postives = 138/254 (54.33%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ + +YYG + L I MEYL + + GP + + K+IL+GL++LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PPN P VL I + L +K K FI+ +N DP+ RPTA ELL
Sbjct: 21 EELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGD--FTKSFKEFIDACLNKDPSFRPTAKELL 269
BLAST of Serine threonine-kinase 25 vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 158.303 bits (399), Expect = 2.599e-42 Identity = 98/254 (38.58%), Postives = 138/254 (54.33%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ + +YYG + L I MEYL + + GP + + K+IL+GL++LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PPN P VL I + L +K K FI+ +N DP+ RPTA ELL
Sbjct: 21 EELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGD--FTKSFKEFIDACLNKDPSFRPTAKELL 269
BLAST of Serine threonine-kinase 25 vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404]) HSP 1 Score: 158.303 bits (399), Expect = 2.983e-42 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQH--SKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404]) HSP 1 Score: 158.303 bits (399), Expect = 2.983e-42 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQH--SKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404]) HSP 1 Score: 158.303 bits (399), Expect = 2.983e-42 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQH--SKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 156.762 bits (395), Expect = 9.382e-41 Identity = 99/253 (39.13%), Postives = 143/253 (56.52%), Query Frame = 1
Query: 853 FEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKY--IEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLN-QENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
F K +IG GSFGEV+K + V AIK + LE + + I+ +I + + + +++ + +Y+G + L I MEYL + K+G L+ + ++IL+GLE+LH+ER IHRDIK AN+LL+ Q VK+ D+GV++ L L T GTP FMAPEV+ G Y+ ADIWS+G T I + G PP+ P VL I + L S+ SK K F+E +N DP RP+A+ LL
Sbjct: 34 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKGANVLLDRQTAAVKICDYGVAKPLDTVL-KANTFVGTPFFMAPEVV----KGEYSIEADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLL 279
BLAST of Serine threonine-kinase 25 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 156.377 bits (394), Expect = 1.138e-40 Identity = 99/253 (39.13%), Postives = 143/253 (56.52%), Query Frame = 1
Query: 853 FEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKY--IEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLN-QENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
F K +IG GSFGEV+K + V AIK + LE + + I+ +I + + + +++ + +Y+G + L I MEYL + K+G L+ + ++IL+GLE+LH+ER IHRDIK AN+LL+ Q VK+ D+GV++ L L T GTP FMAPEV+ G Y+ ADIWS+G T I + G PP+ P VL I + L S+ SK K F+E +N DP RP+A+ LL
Sbjct: 19 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKGANVLLDRQTAAVKICDYGVAKPLDTVL-KANTFVGTPFFMAPEVV----KGEYSIEADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLL 264
BLAST of Serine threonine-kinase 25 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 156.377 bits (394), Expect = 1.267e-40 Identity = 99/253 (39.13%), Postives = 143/253 (56.52%), Query Frame = 1
Query: 853 FEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKY--IEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLN-QENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
F K +IG GSFGEV+K + V AIK + LE + + I+ +I + + + +++ + +Y+G + L I MEYL + K+G L+ + ++IL+GLE+LH+ER IHRDIK AN+LL+ Q VK+ D+GV++ L L T GTP FMAPEV+ G Y+ ADIWS+G T I + G PP+ P VL I + L S+ SK K F+E +N DP RP+A+ LL
Sbjct: 14 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKGANVLLDRQTAAVKICDYGVAKPLDTVL-KANTFVGTPFFMAPEVV----KGEYSIEADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLL 259
BLAST of Serine threonine-kinase 25 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 155.992 bits (393), Expect = 1.870e-40 Identity = 94/252 (37.30%), Postives = 143/252 (56.75%), Query Frame = 1
Query: 853 FEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKY--IEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
F K +IG GSFGEV+K + V AIK + LE + + I+ +I + + + +++ + +Y+G + L I MEYL + K+G L+ + ++IL+GLE+LH+ER IHRDIK AN+L+++ VK+ DFGV+ L+ + T G+P +MAPE+I + Y+ ADIWS+G T I + G PP+ P VL I + L S+ SK K F+E +N DP RP+A+ LL
Sbjct: 34 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRITFVGSPFWMAPELIKQSS---YDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLL 280
BLAST of Serine threonine-kinase 25 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 155.606 bits (392), Expect = 2.010e-40 Identity = 94/252 (37.30%), Postives = 143/252 (56.75%), Query Frame = 1
Query: 853 FEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKY--IEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
F K +IG GSFGEV+K + V AIK + LE + + I+ +I + + + +++ + +Y+G + L I MEYL + K+G L+ + ++IL+GLE+LH+ER IHRDIK AN+L+++ VK+ DFGV+ L+ + T G+P +MAPE+I + Y+ ADIWS+G T I + G PP+ P VL I + L S+ SK K F+E +N DP RP+A+ LL
Sbjct: 14 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEI-QVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRITFVGSPFWMAPELIKQSS---YDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQ-WSKPFKEFVEMCLNKDPENRPSASTLL 260
BLAST of Serine threonine-kinase 25 vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399) HSP 1 Score: 169.088 bits (427), Expect = 5.988e-45 Identity = 102/253 (40.32%), Postives = 139/253 (54.94%), Query Frame = 1
Query: 853 FEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHK---FMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
F K +IG GSFGEVFK + V AIK + LE + + DI + + + ++ + +YYG T L I MEYL + K G E + +++L+GL++LH+ER +HRDIK AN+LL+++ VKL DFGV+ L+ S T GTP +MAPEVI Y+ ADIWS+G T I + G PPN + P VL I + QL S +K K F+E +N DP RPTA ELL
Sbjct: 13 FTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEI--DDIQQEIMVLSQCDSPYVTKYYGSFLKGTKLWIIMEYLGGGSALDLMKAGSFEEMHIGIILREVLKGLDYLHSERKLHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVI---KQSQYDAKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPQLTGS--YTKSFKDFVEACLNKDPENRPTAKELL 258
BLAST of Serine threonine-kinase 25 vs. Ensembl Fly
Match: hppy (gene:FBgn0263395 transcript:FBtr0340456) HSP 1 Score: 135.961 bits (341), Expect = 3.052e-33 Identity = 88/256 (34.38%), Postives = 127/256 (49.61%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIEND--KKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
+ +E KIGSG++G+V+K K + AIK + LE D I M + II YYG + L I ME+ S+++ GPL + ++ L+GLE+LH+ +HRDIK ANILL + VKL DFGVS ++ ++ + GTP++MAPEV + G YN DIW+ G T I + PP P L + K L + + S FI+ + +P +RPTA LL
Sbjct: 23 QDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLL 278
BLAST of Serine threonine-kinase 25 vs. Ensembl Fly
Match: hppy (gene:FBgn0263395 transcript:FBtr0086503) HSP 1 Score: 135.961 bits (341), Expect = 3.204e-33 Identity = 88/256 (34.38%), Postives = 127/256 (49.61%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIEND--KKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
+ +E KIGSG++G+V+K K + AIK + LE D I M + II YYG + L I ME+ S+++ GPL + ++ L+GLE+LH+ +HRDIK ANILL + VKL DFGVS ++ ++ + GTP++MAPEV + G YN DIW+ G T I + PP P L + K L + + S FI+ + +P +RPTA LL
Sbjct: 23 QDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLL 278
BLAST of Serine threonine-kinase 25 vs. Ensembl Fly
Match: hppy (gene:FBgn0263395 transcript:FBtr0340454) HSP 1 Score: 135.961 bits (341), Expect = 3.478e-33 Identity = 88/256 (34.38%), Postives = 127/256 (49.61%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIEND--KKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
+ +E KIGSG++G+V+K K + AIK + LE D I M + II YYG + L I ME+ S+++ GPL + ++ L+GLE+LH+ +HRDIK ANILL + VKL DFGVS ++ ++ + GTP++MAPEV + G YN DIW+ G T I + PP P L + K L + + S FI+ + +P +RPTA LL
Sbjct: 23 QDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLL 278
BLAST of Serine threonine-kinase 25 vs. Ensembl Fly
Match: hppy (gene:FBgn0263395 transcript:FBtr0086504) HSP 1 Score: 135.576 bits (340), Expect = 5.140e-33 Identity = 88/256 (34.38%), Postives = 127/256 (49.61%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIEND--KKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
+ +E KIGSG++G+V+K K + AIK + LE D I M + II YYG + L I ME+ S+++ GPL + ++ L+GLE+LH+ +HRDIK ANILL + VKL DFGVS ++ ++ + GTP++MAPEV + G YN DIW+ G T I + PP P L + K L + + S FI+ + +P +RPTA LL
Sbjct: 23 QDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLL 278
BLAST of Serine threonine-kinase 25 vs. Ensembl Zebrafish
Match: stk25b (serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-GENE-040426-2537]) HSP 1 Score: 164.466 bits (415), Expect = 1.216e-44 Identity = 104/254 (40.94%), Postives = 138/254 (54.33%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ + +YYG T L I MEYL + K GPLE + ++IL+GLE+LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L S SK K F+E +N DP RPTA ELL
Sbjct: 17 EEYFTKQERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKGTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNTPPTLEGS--YSKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Zebrafish
Match: stk24a (serine/threonine kinase 24a (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-070424-52]) HSP 1 Score: 157.918 bits (398), Expect = 2.399e-42 Identity = 100/255 (39.22%), Postives = 142/255 (55.69%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKY--IEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
EK F K +IG GSFGEVFK + V AIK + LE + + I+ +I + + ++ I +Y+G T L I MEYL + G L+ + ++IL+GL++LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PP+ P VL I + L + +K +K F++ +N DPN RPTA ELL
Sbjct: 14 EKLFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEVEDIQQEI-TVLSQCDSLFITKYFGSYLKDTKLWIIMEYLGGGSALDLLGPGALDETHIATILREILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSEYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKENPPTLEGN--YNKALKEFVDACLNKDPNFRPTAKELL 262
BLAST of Serine threonine-kinase 25 vs. Ensembl Zebrafish
Match: stk26 (serine/threonine protein kinase 26 [Source:ZFIN;Acc:ZDB-GENE-080516-5]) HSP 1 Score: 157.147 bits (396), Expect = 4.049e-42 Identity = 98/254 (38.58%), Postives = 135/254 (53.15%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK V AIK + LE + + + + + ++ + +YYG + L I MEYL + + GP + + K+IL+GL++LH+E+ IHRDIK AN+LL++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PPN P VL I + L SK K F++ +N DP RPTA ELL
Sbjct: 21 EELFTKLDRIGKGSFGEVFKGIDRQTQNVVAIKTIDLEEAEDEIEDIQQEITVLSQCDSPHVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEYQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVI---QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFHIPKNTPPTLNGD--FSKIFKEFVDSCLNKDPAFRPTAKELL 269
BLAST of Serine threonine-kinase 25 vs. Ensembl Zebrafish
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 155.992 bits (393), Expect = 1.207e-41 Identity = 100/254 (39.37%), Postives = 138/254 (54.33%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ + +YYG T + L I MEYL + + G LE + ++IL+GL++LH+ER IHRDIK AN+LL++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN + P VL I + L S SK K F+E +N +P RPTA ELL
Sbjct: 17 EEYFTKLERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLTGSKLWIIMEYLGGGSALDLLRPGTLEEVYIATILREILKGLDYLHSERKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNAELHPMRVLFLIPKNNPPTLEGS--YSKAFKDFVEACLNKEPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Zebrafish
Match: stk24b (serine/threonine kinase 24b (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-040426-2841]) HSP 1 Score: 152.14 bits (383), Expect = 3.316e-40 Identity = 97/254 (38.19%), Postives = 139/254 (54.72%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ + +YYG T L I MEYL + + G L+ + ++IL+GLE+LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PP+ P VL I + L + K +K F+E +N +P+ RPTA ELL
Sbjct: 9 EELFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGSLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLEGN--YCKPLKEFVEACLNKEPSFRPTAKELL 257
BLAST of Serine threonine-kinase 25 vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 157.918 bits (398), Expect = 1.308e-42 Identity = 101/254 (39.76%), Postives = 136/254 (53.54%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +YYG + L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PP P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 4 ERLFTKLERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLLKPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQGQ--YSKPFKDFVEACLNKDPRSRPTARELL 252
BLAST of Serine threonine-kinase 25 vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 158.303 bits (399), Expect = 1.564e-42 Identity = 101/254 (39.76%), Postives = 136/254 (53.54%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +YYG + L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PP P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 4 ERLFTKLERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLLKPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQGQ--YSKPFKDFVEACLNKDPRSRPTARELL 252
BLAST of Serine threonine-kinase 25 vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 158.303 bits (399), Expect = 1.870e-42 Identity = 101/254 (39.76%), Postives = 136/254 (53.54%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +YYG + L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PP P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 16 ERLFTKLERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLLKPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQGQ--YSKPFKDFVEACLNKDPRSRPTARELL 264
BLAST of Serine threonine-kinase 25 vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 157.918 bits (398), Expect = 2.323e-42 Identity = 101/254 (39.76%), Postives = 136/254 (53.54%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +YYG + L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PP P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 4 ERLFTKLERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLLKPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQGQ--YSKPFKDFVEACLNKDPRSRPTARELL 252
BLAST of Serine threonine-kinase 25 vs. Ensembl Xenopus
Match: cpvl (carboxypeptidase, vitellogenic-like [Source:Xenbase;Acc:XB-GENE-1014879]) HSP 1 Score: 157.147 bits (396), Expect = 4.881e-42 Identity = 99/254 (38.98%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ + +YYG T L I MEYL + + GP + + K+IL+GL++LH+E IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PPN P VL I + L SK K F++ +N DP+ RPTA ELL
Sbjct: 9 EELFTKLERIGKGSFGEVFKGIDNRTQHVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKGTKLWIIMEYLGGGSALDLLRVGPFDEFQIATMLKEILKGLDYLHSENKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPSLTGD--FSKPFKEFVDACLNKDPSFRPTARELL 257
BLAST of Serine threonine-kinase 25 vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665]) HSP 1 Score: 157.532 bits (397), Expect = 2.034e-42 Identity = 98/254 (38.58%), Postives = 138/254 (54.33%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ + +YYG + L I MEYL + + GP + + K+IL+GL++LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PPN P VL I + L +K K FI+ +N DP+ RPTA ELL
Sbjct: 21 EELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLIGD--FTKSFKEFIDACLNKDPSFRPTAKELL 269
BLAST of Serine threonine-kinase 25 vs. Ensembl Mouse
Match: Stk25 (serine/threonine kinase 25 (yeast) [Source:MGI Symbol;Acc:MGI:1891699]) HSP 1 Score: 157.918 bits (398), Expect = 2.768e-42 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGHH--SKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665]) HSP 1 Score: 157.532 bits (397), Expect = 3.103e-42 Identity = 98/254 (38.58%), Postives = 138/254 (54.33%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ + +YYG + L I MEYL + + GP + + K+IL+GL++LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PPN P VL I + L +K K FI+ +N DP+ RPTA ELL
Sbjct: 21 EELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLIGD--FTKSFKEFIDACLNKDPSFRPTAKELL 269
BLAST of Serine threonine-kinase 25 vs. Ensembl Mouse
Match: Stk24 (serine/threonine kinase 24 [Source:MGI Symbol;Acc:MGI:2385007]) HSP 1 Score: 156.377 bits (394), Expect = 1.279e-41 Identity = 100/258 (38.76%), Postives = 143/258 (55.43%), Query Frame = 1
Query: 832 KSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
K+ E+ F K KIG GSFGEVFK + V AIK + LE + + + + + ++ + +YYG T L I MEYL + + GPL+ + ++IL+GL++LH+E+ IHRDIK AN+LL++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PP+ + P VL I + L + SK +K F+E +N +P+ RPTA ELL
Sbjct: 17 KADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLEGN--YSKPLKEFVEACLNKEPSFRPTAKELL 269
BLAST of Serine threonine-kinase 25 vs. Ensembl Mouse
Match: Stk25 (serine/threonine kinase 25 (yeast) [Source:MGI Symbol;Acc:MGI:1891699]) HSP 1 Score: 137.887 bits (346), Expect = 7.700e-37 Identity = 85/211 (40.28%), Postives = 117/211 (55.45%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVL 1473
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL
Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVL 224
BLAST of Serine threonine-kinase 25 vs. UniProt/SwissProt
Match: sp|Q54PX0|Y4251_DICDI (Probable serine/threonine-protein kinase DDB_G0284251 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0284251 PE=3 SV=1) HSP 1 Score: 164.081 bits (414), Expect = 5.479e-43 Identity = 96/268 (35.82%), Postives = 159/268 (59.33%), Query Frame = 1
Query: 829 KKSI-REKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDS---KYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLF 1617
KKSI + + G KIG G+FG+VFK AIK + ID + ++G++ + + KL + I++ GV++ + L +EY+ S+ + I K GPL + + Y Q+L+GL +LH+ ++IHRDIK +NIL+ +E +KL DFGV+ + E +V GTP++MAPE I + +G ++++DIWS+G+T+I ++TG+PP + +P + I +D+ P+ +SKE + ++ DP +RPTA ELL +F
Sbjct: 27 KKSIVKIGEYTLGEKIGRGAFGQVFKGLNGKTGEFVAIKQIDSNKIDESSLQSVKGEV-EILHKLRHNNIVKVLGVVEVQAQLNFILEYVENGSLRDVIEKFGPLSEELCIIYLYQMLQGLAYLHSNKVIHRDIKASNILITKEGVIKLADFGVASQIDSESQLRFSVVGTPYWMAPESI--EISG-CSSASDIWSLGSTMIELLTGNPPYYTLQPMAAMFRIVSDQHPPFPTD--ISKEFLDYFQQSFKKDPTQRPTAQELLQHPIF 288
BLAST of Serine threonine-kinase 25 vs. UniProt/SwissProt
Match: sp|Q9P289|STK26_HUMAN (Serine/threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2) HSP 1 Score: 158.303 bits (399), Expect = 1.248e-41 Identity = 98/254 (38.58%), Postives = 138/254 (54.33%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ + +YYG + L I MEYL + + GP + + K+IL+GL++LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PPN P VL I + L +K K FI+ +N DP+ RPTA ELL
Sbjct: 21 EELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGD--FTKSFKEFIDACLNKDPSFRPTAKELL 269
BLAST of Serine threonine-kinase 25 vs. UniProt/SwissProt
Match: sp|O00506|STK25_HUMAN (Serine/threonine-protein kinase 25 OS=Homo sapiens OX=9606 GN=STK25 PE=1 SV=1) HSP 1 Score: 158.303 bits (399), Expect = 1.432e-41 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQH--SKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. UniProt/SwissProt
Match: sp|Q9Z2W1|STK25_MOUSE (Serine/threonine-protein kinase 25 OS=Mus musculus OX=10090 GN=Stk25 PE=1 SV=2) HSP 1 Score: 157.918 bits (398), Expect = 1.936e-41 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGHH--SKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. UniProt/SwissProt
Match: sp|Q3SWY6|STK25_BOVIN (Serine/threonine-protein kinase 25 OS=Bos taurus OX=9913 GN=STK25 PE=2 SV=1) HSP 1 Score: 157.918 bits (398), Expect = 2.056e-41 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 17 EELFTKLDRIGKGSFGEVYKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGHH--SKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. TrEMBL
Match: A0A0H3YJG2 (Slc42a-1 OS=Schmidtea mediterranea OX=79327 GN=slc42a-1 PE=2 SV=1) HSP 1 Score: 221.861 bits (564), Expect = 6.648e-59 Identity = 157/509 (30.84%), Postives = 250/509 (49.12%), Query Frame = 1
Query: 106 KLFHRFFKREYLERE---DLNKKRPIHHACECGQVEIVRLLIDHK-CDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQSGELPSRPIIHIDNGPRLLRACENGDLRSFLEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQLDEQIF-KMGLECRWGCDHKLCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSG---ELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTL 1608
+L + FF + LE E + K + A + G +E V+ + +I+ SR PI +AC GH + I + C+ ++ D + ++YA ++ +++L +SG + P D PIH AC+ I+ QLL+E C++ DK SPL IA+ + ++ +I+ E Q+ +I +M L+C C+HK C S + K + I SGS+G VF SG FA+K + + I ++YIE +I+ F L +ERI++++G K + IFMEYL ++K K P D++ ++KQILE L FLH IIHRDIKP N+LL+ + +KL+DFG+S LLS ++ CGT + APE++ A+ Y S DIWS+GAT+I + TG PP H ++ I ++++ E M K + I+ M+ D +R +A +LL +
Sbjct: 485 QLVYEFFIFDRLEYERYSEFEKFGQLIKAIKDGSIEDVKKYYSRRILEIKLGSYSR-SPILYACKYGHRKIVKYFIKQKCNVDSFDCEFRRALHYAVISNNNDIVKLL--------IESGAAINVP----------------------------------DSLLMMPIHLACKVNNIEAAQLLMENNCDMVTLDKLKRSPLQIAETGDFENMIKLIK----ECQIIREIAAEMQLKCGKLCNHKFCYTSFQRKKIKNRKCIASGSYGTVFLYNESGTDRKFAVKKIPKQNIRARYIEANINDFKNLLCHERIVKHFGAFHKKENHYIFMEYLDTLQKKKYQKKSP---GDLLLFAKQILEALSFLHERSIIHRDIKPENVLLDIDGNLKLSDFGLSLLLSSVAEDIQKEGRCCGTYCYAAPEILNAEL---YTCSVDIWSLGATMIQLCTGQPPYHNLGDGAIITVISTTREIEYKLPEYMPKYISNLIDHMLEKDQYKRLSAKKLLGM 940
BLAST of Serine threonine-kinase 25 vs. TrEMBL
Match: A7S4G7 (Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g104385 PE=4 SV=1) HSP 1 Score: 174.481 bits (441), Expect = 1.421e-46 Identity = 109/268 (40.67%), Postives = 150/268 (55.97%), Query Frame = 1
Query: 850 NFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDS------KYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPT--TVCGTPHFMAPEVILADTNG-PYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIEND-KKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLFS 1620
N+ KG +G+G+FG+V+ C A+K + ++S K +EG+I +FM NERI+QYYG+ H+ IFMEYLP SI E I ++G L +YS+QILEG+ +LH RI+HRDIK ANIL + VKL DFG S+ L S +V GTP++MAPEVI NG Y AD+WSVG TV+ M+T PP P L +I + +LPS +S + F+ + + RP+A ELL S +
Sbjct: 3 NWRKGKLLGAGAFGQVYMCHDLDTGRELAVKQIETGQLNSSTKNEVKALEGEI-EFMKAFRNERIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKRLQTIRSKTGFRSVHGTPYWMAPEVI----NGEGYGRKADVWSVGCTVVEMLTTKPPWADFEPMAALFKIATQPTEPELPSD--LSVDAVEFVRSTLRMNSKSRPSADELLRFSFVT 263
BLAST of Serine threonine-kinase 25 vs. TrEMBL
Match: A0A0G4EFQ9 (Protein kinase domain-containing protein OS=Vitrella brassicaformis (strain CCMP3155) OX=1169540 GN=Vbra_11795 PE=4 SV=1) HSP 1 Score: 174.096 bits (440), Expect = 7.608e-44 Identity = 107/274 (39.05%), Postives = 154/274 (56.20%), Query Frame = 1
Query: 823 LCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKF------MPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLS--GELSNPTTVC----GTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPP-NHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
L +++I EK+ + G K+G+GS+G V+ + + A+K + L S+ + + +F + L + I+ Y GV+QT L I MEY+P S++ I K GPL+ V ++ QIL+GL +LH I+HRDIK NILL + VKL DFG +R+L GE S +C GTP +MAPEV+ + PY+T ADIWSVG TVI MITG PP + P L I ++ P + K + FI + + P+ERPTA+ LL
Sbjct: 239 LTEETITEKDLQMGQKLGAGSYGTVYLAMHTHTGQLLALKQVELA-THSQAQQSQLMEFQHEMGLLKSLQHPNIVSYIGVVQTPVSLNILMEYVPGGSLQSLIGKFGPLKESVVALFTHQILQGLAYLHEHNIVHRDIKGGNILLRADGVVKLADFGCARVLDREGESSTEKDMCMTTKGTPLWMAPEVLAKE---PYSTPADIWSVGCTVIEMITGQPPWSEYGSPWAALYAIVKARR-SPPIRSDIPKGAQAFIAECLRFTPSERPTASALL 507
BLAST of Serine threonine-kinase 25 vs. TrEMBL
Match: T1G1N2 (Protein kinase domain-containing protein OS=Helobdella robusta OX=6412 GN=20214980 PE=4 SV=1) HSP 1 Score: 166.777 bits (421), Expect = 1.039e-43 Identity = 100/267 (37.45%), Postives = 148/267 (55.43%), Query Frame = 1
Query: 850 NFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH------KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSG----------ELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSEL---MSKEMKTFIEKMMNPDPNERPTA 1590
N++KG +G+G FG+V+ C A+K + + + S+ I ++ K + L+N RI+QYYG + L IFME++P S++++I GPL RY+KQ+LEGLEFLH+ I+HRDIK ANIL + E +KLTDFG ++ LS L+ T+ GTP++M+PE+I Y DIWS+G TV+ M+TGHPP H+ + +I PS +L S ++K F+ DP RP+A
Sbjct: 4 NWKKGKILGAGGFGQVYLCYDVDTGVELAVKQVNV-YCQSEDISKEVRALQSEIKLLQDLSNPRIVQYYGSQKEPHMLSIFMEFVPGGSVKDQIQDYGPLTESVTKRYTKQVLEGLEFLHSLMIVHRDIKGANILRDHEGNIKLTDFGAAKRLSSIVNKTADVSKNLTGAKTMTGTPYYMSPEIIEGKR---YGRKVDIWSLGCTVVEMLTGHPPWHEYEGVAAIFKIATQPH---PSYKLPPDTSLQVKDFLSCCFERDPERRPSA 263
BLAST of Serine threonine-kinase 25 vs. TrEMBL
Match: F4Q7I1 (Protein kinase domain-containing protein OS=Cavenderia fasciculata (strain SH3) OX=1054147 GN=DFA_09394 PE=4 SV=1) HSP 1 Score: 173.711 bits (439), Expect = 1.486e-43 Identity = 98/266 (36.84%), Postives = 156/266 (58.65%), Query Frame = 1
Query: 829 KKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEG--DIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLF 1617
K+++R + G KIG G++G+V+K S AIK + ID+ ++ + + KLN+ I++ G +++++ L +EY+ S+ + + K GPL + Y Q+L+GL +LH RIIHRDIK +NIL+ +E +KL DFGV+ LS E+ +V GTP++MAPE I T ++S+DIWS+ T+I +ITGHPP + +P + +I D P++ +SK+ + F+ DPN+RPTA ELL +F
Sbjct: 71 KETVRIGEYAIGDKIGKGAYGQVYKGLNSKTGDFVAIKQIDRIKIDANTLQSVKSEVEILQKLNHNNIVKVLGCVESQSQLNFILEYVENGSLRDVVEKFGPLSEELATVYLYQLLQGLAYLHTNRIIHRDIKCSNILITKEGVIKLADFGVASQLSDEVQLRYSVVGTPYWMAPEAI---TISGQSSSSDIWSLACTMIELITGHPPYYNLQPMSAMFKIVQDPHPPYPAN--ISKQFEDFLNVSFEKDPNKRPTAAELLRHPIF 331
BLAST of Serine threonine-kinase 25 vs. Ensembl Cavefish
Match: stk25b (serine/threonine-protein kinase 25-like [Source:NCBI gene;Acc:103039280]) HSP 1 Score: 162.54 bits (410), Expect = 3.810e-44 Identity = 103/254 (40.55%), Postives = 138/254 (54.33%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ + +YYG T L I MEYL + + GPLE + ++IL+GLE+LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L S SK K F+E +N DP RPTA ELL
Sbjct: 21 EEYFTKQERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLLRPGPLEETYIATILREILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNPPPTLEGS--YSKPFKEFVEACLNKDPRFRPTAKELL 269
BLAST of Serine threonine-kinase 25 vs. Ensembl Cavefish
Match: stk25b (serine/threonine-protein kinase 25-like [Source:NCBI gene;Acc:103039280]) HSP 1 Score: 162.54 bits (410), Expect = 4.691e-44 Identity = 103/254 (40.55%), Postives = 138/254 (54.33%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ + +YYG T L I MEYL + + GPLE + ++IL+GLE+LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L S SK K F+E +N DP RPTA ELL
Sbjct: 17 EEYFTKQERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLLRPGPLEETYIATILREILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNPPPTLEGS--YSKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Cavefish
Match: stk25a (serine/threonine-protein kinase 25 [Source:NCBI gene;Acc:103021644]) HSP 1 Score: 160.229 bits (404), Expect = 3.559e-43 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ + +Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L S SK K F+E +N DP RPTA ELL
Sbjct: 17 EQYFTKLERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYFGSYLKSTKLWIIMEYLGGGSALDMLKPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGS--YSKAFKDFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Cavefish
Match: stk26 (serine/threonine kinase 26 [Source:NCBI gene;Acc:103024322]) HSP 1 Score: 157.532 bits (397), Expect = 2.589e-42 Identity = 98/254 (38.58%), Postives = 135/254 (53.15%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK V AIK + LE + + + + + ++ + +YYG + L I MEYL + + GP + + K+IL+GL++LH+E+ IHRDIK AN+LL++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PPN P VL I + L SK K F++ +N DP RPTA ELL
Sbjct: 21 EELFTKLERIGKGSFGEVFKGIDRRTQNVVAIKTIDLEEAEDEIEDIQQEITVLSQCDSPHVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDECQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVI---QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFHIPKNTPPTLNGD--FSKSFKEFVDSCLNKDPTFRPTAKELL 269
BLAST of Serine threonine-kinase 25 vs. Ensembl Cavefish
Match: ENSAMXT00000008518.2 (pep primary_assembly:Astyanax_mexicanus-2.0:19:14507502:14520436:1 gene:ENSAMXG00000008289.2 transcript:ENSAMXT00000008518.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 157.147 bits (396), Expect = 2.760e-42 Identity = 100/258 (38.76%), Postives = 143/258 (55.43%), Query Frame = 1
Query: 832 KSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
K+ E+ F K KIG GSFGEVFK + V AIK + LE + + + + + ++ + +YYG T L I MEYL + + GPL+ + ++IL+GLE+LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PP+ + P VL I + L + K +K F+E +N +P+ RPTA ELL
Sbjct: 14 KADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLEGN--YCKPLKEFVEACLNKEPSFRPTAKELL 266
BLAST of Serine threonine-kinase 25 vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 155.221 bits (391), Expect = 6.326e-42 Identity = 101/256 (39.45%), Postives = 138/256 (53.91%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIK--PANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ + Y+G T L I MEYL + K GPLE + ++IL+GL++LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN + P VL I + L + SK K F++ +N DP RPTA ELL
Sbjct: 23 EELFTKQERIGKGSFGEVFKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTHYFGSYLKGTKLWIIMEYLGGGSALDLIKPGPLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTLEGN--YSKAFKEFVDSCLNKDPQFRPTAKELL 273
BLAST of Serine threonine-kinase 25 vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 143.28 bits (360), Expect = 9.492e-37 Identity = 98/268 (36.57%), Postives = 147/268 (54.85%), Query Frame = 1
Query: 850 NFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILE------FIDSKYIEGDIHKFMPKLNNERIIQYYGVI---QTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPT---TVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIE---NDKKLQLPSSELMSKEM-KTFIEKMMNPDPNERPTATELL 1602
N+++G +G G+FG V+ C + A+K + + + +E +I + + L +ERI+QY+G + Q KT L IFMEY+P SI++++ G L +Y++QILEG+ FLH I+HRDIK ANIL + VKL DFG S+ L S T +V GTP++M+PEVI + Y ADIWSVG TV+ M+T PP + + +I D +L L +SE + + F+E + RP+A +LL
Sbjct: 358 NWQRGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPGSVETSKEVNALECEI-QLLKNLQHERIVQYFGCLRDPQQKT-LSIFMEYMPGGSIKDQLRAYGALTENVTRKYTRQILEGVSFLHGNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICSQGTAMRSVTGTPYWMSPEVINGEG---YGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTDPRLPLHASEHARDLLRRIFVEAKL------RPSAEDLL 614
BLAST of Serine threonine-kinase 25 vs. Ensembl Sea Lamprey
Match: MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6865]) HSP 1 Score: 141.739 bits (356), Expect = 9.117e-36 Identity = 85/266 (31.95%), Postives = 140/266 (52.63%), Query Frame = 1
Query: 823 LCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIEND--KKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLS 1611
+ +++++E +FE ++GSG++G+V K + + AIK + LE D + M + + I+ YYG L I ME+ S+++ + GPL + + +++ L+GL +LH+E +HRDIK ANILL + VKL DFGVS ++ ++ + GTP++MAPEV + G YN D+W+VG T I + PP P L + + +L + S FI+ + +P +RPTA ++LT S
Sbjct: 5 ISRRTLQE-DFELAERLGSGTYGDVHKARNVQTGELVAIKIIKLEPGDDFSVIQQEIVMMKECKHTNIVAYYGSYLRHDKLWICMEHCGGGSLQDIYHVTGPLTERQIAYVTRETLQGLAYLHSEGKMHRDIKGANILLTDDGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNHQCDVWAVGITAIELAELQPPMFDLHPMRALFLMSKSGFQPPKLRDKQKWSPVFHNFIKMALTKNPKKRPTAEKMLTHS 269
BLAST of Serine threonine-kinase 25 vs. Ensembl Sea Lamprey
Match: slka (STE20-like kinase a [Source:ZFIN;Acc:ZDB-GENE-050411-66]) HSP 1 Score: 134.035 bits (336), Expect = 3.848e-33 Identity = 99/296 (33.45%), Postives = 152/296 (51.35%), Query Frame = 1
Query: 775 QIFKMGLECRWGCDHKLCKKSIREKNF-EKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKL------NNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKIN---KNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADT--NGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEI-END-KKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLFS 1620
+IFK+G E R + ++ + ++G G+FG+V+K + + A K I++K E ++ +M ++ ++ I+ + L IF+E+ P + I + G E Q V KQ+LE L +LH RIIHRD+K NILL E VKL DFGVS + L + GTP++MAPEV++ +T + PY+ ADIWS+G T+I + PPNH+ P V+ +I +ND L PS S E F++K ++ +P R A +LL S S
Sbjct: 6 KIFKLGSERRKPKQYDHVRRDVDPAELWSVIGELGDGAFGKVYKAQNKESGVLAAAK-----VIETKS-EEELEDYMVEIEILALCDHPNIVGLLNAFYYENKLWIFIEFCPGGAVDAIMLELERGLAEPQIRV-VCKQMLEALNYLHTHRIIHRDLKAGNILLTFEGDVKLADFGVSAKNTRTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIELAQMEPPNHELNPMRVMLKIAKNDPPSLSFPSK--WSAEFTDFLKKCLDKNPETRWNALQLLQHSFIS 292
BLAST of Serine threonine-kinase 25 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002962.1 (pep scaffold:Pmarinus_7.0:GL476671:16080:33623:-1 gene:ENSPMAG00000002691.1 transcript:ENSPMAT00000002962.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 126.716 bits (317), Expect = 7.092e-31 Identity = 89/258 (34.50%), Postives = 124/258 (48.06%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDI---HKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKIN-KNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPT-TVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
EK F +IG GSFG V+ + V AIK + S DI KF+ KL + II+Y G + + MEY S + + PL+ ++ + L+GL FLHN +IHRD+K NILL + VKL DFG S L+ P + GTP++MAPEVILA G Y+ D+WS+G T I + PP L I + L S E S + F++ + + +RPT+ LL
Sbjct: 27 EKLFCDLKEIGHGSFGAVYFARNIHTSEVVAIKKMSYSGKQSNEKWQDIIKEVKFLTKLKHPNIIEYKGCYLREHTAWMIMEYCLGSASDLLEVHKKPLQEIEIAAIAHGALQGLAFLHNHTMIHRDVKAGNILLTEPGQVKLADFG-----SASLTAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSPE-WSDYFRNFVDSCLQKNGQDRPTSAGLL 278
BLAST of Serine threonine-kinase 25 vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 142.51 bits (358), Expect = 3.121e-36 Identity = 94/247 (38.06%), Postives = 141/247 (57.09%), Query Frame = 1
Query: 871 IGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDS-KYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGP-LETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
IG GS+G V+K V AIK ++ E + I +I + LN+ I++Y+G I+ L I +EY S+ I+++ L + Y Q L GL++LH E +IHRDIK ANILL+ +N VKL DFGVS +++ S+ T+ GT ++MAPE++ N +T +DIWS+GATV+ M+T +PP H ++ +END PSS S+ +K F+ K + +RPTA +LL
Sbjct: 31 IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEI-SLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVN---SSALTLAGTLNWMAPEIL---GNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYP-PSS--FSEPLKDFLSKCFVKNMYKRPTADQLL 267
BLAST of Serine threonine-kinase 25 vs. Ensembl Yeast
Match: STE11 (Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]) HSP 1 Score: 135.191 bits (339), Expect = 6.235e-34 Identity = 97/300 (32.33%), Postives = 146/300 (48.67%), Query Frame = 1
Query: 847 KNFEKGSKIGSGSFGEVF------------------KCKGSGIPT-----------------------VFAIKY-LILEFIDSKYIEGDIHK--FMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLS---GELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
KN+ KG+ IGSGSFG V+ K G+PT V A+ + + I K ++ H+ + +L++E I+ YYG Q +L IF+EY+P S+ +N GP E + +++QIL G+ +LH + IIHRDIK ANIL++ + CVK+TDFG+S+ LS + + ++ G+ +M+PEV+ ADIWS G VI M TG P + +I + ++PS + E K F+ K D RP+A ELL
Sbjct: 413 KNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVV---KQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPS--WATSEGKNFLRKAFELDYQYRPSALELL 707
BLAST of Serine threonine-kinase 25 vs. Ensembl Yeast
Match: SPS1 (Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]) HSP 1 Score: 131.724 bits (330), Expect = 1.797e-33 Identity = 93/256 (36.33%), Postives = 132/256 (51.56%), Query Frame = 1
Query: 871 IGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDS--KYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLP----QSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDK--KLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSL 1614
IG G+FG+V+K + AIK + LE D + + +I F+ +L + I Y + + I MEY + ++ NG L + V ++ GL++LH +R IHRDIK ANILLN+E VKL DFGVS + L T V GTP++MAPEV+ + +G YN ADIWS+G T ++ G PP K P V+ + K KLQ P S K F+ + P +RP+A LL+
Sbjct: 24 IGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIF-FLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNG-LPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFV-GTPYWMAPEVVCCEVDG-YNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGP----FSDAAKDFVAGCLVKTPADRPSAYNLLSFEF 271
BLAST of Serine threonine-kinase 25 vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]) HSP 1 Score: 127.487 bits (319), Expect = 1.651e-31 Identity = 77/266 (28.95%), Postives = 137/266 (51.50%), Query Frame = 1
Query: 841 REKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYI------EGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLF 1617
R K++ +G +G G F F+ K +FA K + I S+ E IHK M N I+Q+ + +++ I +E P S+ E + + L +V ++ QI ++++H+ R+IHRD+K NI + +K+ DFG++ +L+ E T+CGTP+++APEV++ +G ++ DIWS+G + ++ G PP + + I+ + P + +S E K I +++ DP ERP+ TE++ F
Sbjct: 78 RGKDYHRGHFLGEGGFARCFQIKDDS-GEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPN---IVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSG-HSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKC-RDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWF 337
BLAST of Serine threonine-kinase 25 vs. Ensembl Yeast
Match: SSK22 (MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000669]) HSP 1 Score: 125.176 bits (313), Expect = 1.779e-30 Identity = 86/272 (31.62%), Postives = 134/272 (49.26%), Query Frame = 1
Query: 853 FEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYL-ILEFIDSKYIEGDIHKFMP---KLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVR-YSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSG----------------ELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPE-DVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
++K S IG G+FG+V+ + A+K + I + K I I + M LN+ I+QYYGV + + IFMEY + +G +E + V + Y+ ++LEGL +LH ++HRDIKP NILL+ +K DFG +R + G E + + GTP +MAPE I + D+W++G V+ M TG P E ++ + + QLP+ + M+ + F+E+ + DP R TA ELL
Sbjct: 1034 WQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELL 1305
BLAST of Serine threonine-kinase 25 vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7]) HSP 1 Score: 174.481 bits (441), Expect = 1.665e-50 Identity = 109/268 (40.67%), Postives = 150/268 (55.97%), Query Frame = 1
Query: 850 NFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDS------KYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPT--TVCGTPHFMAPEVILADTNG-PYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIEND-KKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLFS 1620
N+ KG +G+G+FG+V+ C A+K + ++S K +EG+I +FM NERI+QYYG+ H+ IFMEYLP SI E I ++G L +YS+QILEG+ +LH RI+HRDIK ANIL + VKL DFG S+ L S +V GTP++MAPEVI NG Y AD+WSVG TV+ M+T PP P L +I + +LPS +S + F+ + + RP+A ELL S +
Sbjct: 3 NWRKGKLLGAGAFGQVYMCHDLDTGRELAVKQIETGQLNSSTKNEVKALEGEI-EFMKAFRNERIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKRLQTIRSKTGFRSVHGTPYWMAPEVI----NGEGYGRKADVWSVGCTVVEMLTTKPPWADFEPMAALFKIATQPTEPELPSD--LSVDAVEFVRSTLRMNSKSRPSADELLRFSFVT 263
BLAST of Serine threonine-kinase 25 vs. Ensembl Nematostella
Match: EDO31934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI4]) HSP 1 Score: 157.918 bits (398), Expect = 5.498e-43 Identity = 98/254 (38.58%), Postives = 140/254 (55.12%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
EK F K +IG GSFGEVFK + V AIK + LE + + + + + ++ + +Y+G T L I MEYL + K G +E + +++L+GL++LH E+ +HRDIK AN+L+++ VKL DFGV+ L+ L+ T GTP +MAPEVI Y++ ADIWS+G T I + G PPN P VL I + +L + SK K F+ +N DPN+RPTA ELL
Sbjct: 8 EKLFSKLERIGKGSFGEVFKGIDNRTNEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSLYVTKYHGSYLKGTKLWIIMEYLGGGSALDLMKAGNIEEFYIATILREVLKGLDYLHTEKKLHRDIKAANVLMSETGDVKLADFGVAGQLTDTLNKRNTFVGTPFWMAPEVI---KQSAYDSKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPELTGN--FSKAFKEFVSLCLNKDPNDRPTAKELL 256
BLAST of Serine threonine-kinase 25 vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9]) HSP 1 Score: 139.813 bits (351), Expect = 3.982e-37 Identity = 99/271 (36.53%), Postives = 137/271 (50.55%), Query Frame = 1
Query: 820 KLCKKSIR---EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINK--NGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLF 1617
KL ++S+ E+ F+ K+G GS+G VFK V AIK + ++ D + I +I M + ++ +++YYG T L I MEY + K N L +++ K L+GLE+LH R IHRDIK NILLN E KL DFGV+ L+ ++ TV GTP +MAPEVI Y+ ADIWS+G T + M G PP P + I S++ K F+ K + +P ER TATELL S
Sbjct: 10 KLSEESLTRPPEEVFDVLEKLGEGSYGSVFKAMHKESGQVVAIKQVPVD-TDLQEIIKEI-SMMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI---QEVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPGQWSEDFKDFVSKCLVKNPEERATATELLQHSFI 275
BLAST of Serine threonine-kinase 25 vs. Ensembl Nematostella
Match: EDO49047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHW1]) HSP 1 Score: 134.035 bits (336), Expect = 3.294e-35 Identity = 87/260 (33.46%), Postives = 135/260 (51.92%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDS-KYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSS----ELMSKEMKTFIEKMMNPDPNERPTATELLT 1605
+K F+ K+G G++G+VFK + + A+K + +E D + I+ +I M + + II Y G + L I MEY SI++ GP + + + L+GL +LH + ++HRDIK ANILL VKL DFG+S ++ + + GTP++MAPE+ + G Y+ DIW+VG T I M PP P L I KK +P + + S EM FI+ + +P +RP+A ++LT
Sbjct: 15 DKVFDLIEKVGGGTYGDVFKARVIATGDLAAVKVVKVEPGDDFELIQQEI-AMMQQCRHNNIINYIGAYMRRDKLWIGMEYCGGGSIQDVYCVTGPCSETQISFVTVETLKGLAYLHEKSLMHRDIKGANILLTTNGEVKLADFGISARITETMKKRKSFIGTPYWMAPEMAAVERTGGYDLKCDIWAVGITAIEMAELQPPMFDLHPMRALYII--GKKSFIPPTLKEKDKWSNEMHHFIKVALIKNPKKRPSADKMLT 271
BLAST of Serine threonine-kinase 25 vs. Ensembl Nematostella
Match: EDO35743 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKK8]) HSP 1 Score: 123.635 bits (309), Expect = 1.448e-32 Identity = 71/205 (34.63%), Postives = 114/205 (55.61%), Query Frame = 1
Query: 1015 NERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVC--GTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIE-NDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLF 1617
+E +++ YG +QT+ + IFMEY+ S+E ++ NG + V + ILE L +LH++ ++H D+K N+L++ + VKL DFG S L ++ + GT FM+PEV ++ P+ S DIWS T+ M+TG PP + +L ++ K +P S S+E+K F+ M + P +RPTA ELL +F
Sbjct: 1 HENVVKLYGAVQTEQKIIIFMEYMDGGSVEMFLSNNGSADEDSVKCVMQVILEALCWLHSKGVVHLDLKGGNVLMDSKGIVKLADFGASVHLDDTTTHTRNIIPRGTEAFMSPEVCRSE---PFGRSTDIWSAACTLYQMLTGEPPWMQYSGGSILYQVAIATKPPGIPDSLECSQEIKDFMASMFSFVPEDRPTAAELLKNPIF 202
BLAST of Serine threonine-kinase 25 vs. Ensembl Medaka
Match: stk25b (serine/threonine kinase 25 [Source:NCBI gene;Acc:101157729]) HSP 1 Score: 161.77 bits (408), Expect = 1.313e-43 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ + +YYG T L I MEYL + + GPLE + ++IL+GLE+LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 17 EEYFTKQERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKGTKLWIIMEYLGGGSALDLLRPGPLEETYIATILREILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNTPPTLEGP--YSKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Medaka
Match: stk25b (serine/threonine kinase 25 [Source:NCBI gene;Acc:101157729]) HSP 1 Score: 161.384 bits (407), Expect = 1.429e-43 Identity = 102/254 (40.16%), Postives = 137/254 (53.94%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEV+K + V AIK + LE + + + + + ++ + +YYG T L I MEYL + + GPLE + ++IL+GLE+LH+ER IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI Y+ ADIWS+G T I + G PPN P VL I + L SK K F+E +N DP RPTA ELL
Sbjct: 17 EEYFTKQERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKGTKLWIIMEYLGGGSALDLLRPGPLEETYIATILREILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNTPPTLEGP--YSKPFKEFVEACLNKDPRFRPTAKELL 265
BLAST of Serine threonine-kinase 25 vs. Ensembl Medaka
Match: ENSORLT00000022068.2 (serine/threonine-protein kinase 24 [Source:NCBI gene;Acc:105356828]) HSP 1 Score: 159.073 bits (401), Expect = 5.660e-43 Identity = 101/254 (39.76%), Postives = 142/254 (55.91%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + + GPL+ + ++IL+GLE+LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI + Y++ ADIWS+G T I + G PP+ P VL I + L + SK +K FIE +N DP+ RPTA ELL
Sbjct: 19 EEMFTKLDRIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCHSPFITKYFGSYLKSTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSS---YDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLEGN--YSKALKEFIEACLNKDPSFRPTAKELL 267
BLAST of Serine threonine-kinase 25 vs. Ensembl Medaka
Match: ENSORLT00000022064.2 (serine/threonine-protein kinase 24 [Source:NCBI gene;Acc:105356828]) HSP 1 Score: 159.458 bits (402), Expect = 7.447e-43 Identity = 101/254 (39.76%), Postives = 142/254 (55.91%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + + GPL+ + ++IL+GLE+LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI + Y++ ADIWS+G T I + G PP+ P VL I + L + SK +K FIE +N DP+ RPTA ELL
Sbjct: 19 EEMFTKLDRIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCHSPFITKYFGSYLKSTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSS---YDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLEGN--YSKALKEFIEACLNKDPSFRPTAKELL 267
BLAST of Serine threonine-kinase 25 vs. Ensembl Medaka
Match: ENSORLT00000022066.2 (serine/threonine-protein kinase 24 [Source:NCBI gene;Acc:105356828]) HSP 1 Score: 159.458 bits (402), Expect = 7.447e-43 Identity = 101/254 (39.76%), Postives = 142/254 (55.91%), Query Frame = 1
Query: 844 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIH-KFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELL 1602
E+ F K +IG GSFGEVFK + V AIK + LE + + + + + ++ I +Y+G T L I MEYL + + GPL+ + ++IL+GLE+LH+E+ IHRDIK AN+LL+++ VKL DFGV+ L+ T GTP +MAPEVI + Y++ ADIWS+G T I + G PP+ P VL I + L + SK +K FIE +N DP+ RPTA ELL
Sbjct: 19 EEMFTKLDRIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCHSPFITKYFGSYLKSTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSS---YDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLEGN--YSKALKEFIEACLNKDPSFRPTAKELL 267
BLAST of Serine threonine-kinase 25 vs. Planmine SMEST
Match: SMESG000016973.1 (SMESG000016973.1) HSP 1 Score: 1079.7 bits (2791), Expect = 0.000e+0 Identity = 518/524 (98.85%), Postives = 520/524 (99.24%), Query Frame = 1
Query: 49 MSNSEHYQCFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQSGELPSRPIIHIDNGPRLLRACENGDLRSFLEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQLDEQIFKMGLECRWGCDHKLCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLSGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLFS 1620
MSNSEHYQCFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQS ELPSRPIIHIDNGPRLLRACENGDLRSFLEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQLDEQIFKMGLECRWGCDHKLCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGL+FLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLL GELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVL EI NDKKLQLPSSE+MSKEMKTFIEKMMNPDPNERPTATELLTLSLFS
Sbjct: 1 MSNSEHYQCFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQSAELPSRPIIHIDNGPRLLRACENGDLRSFLEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQLDEQIFKMGLECRWGCDHKLCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQSIEEKINKNGPLETQDVVRYSKQILEGLQFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLCGELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLIEIANDKKLQLPSSEMMSKEMKTFIEKMMNPDPNERPTATELLTLSLFS 524
BLAST of Serine threonine-kinase 25 vs. Planmine SMEST
Match: SMESG000017261.1 (SMESG000017261.1) HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0 Identity = 293/568 (51.58%), Postives = 383/568 (67.43%), Query Frame = 1
Query: 61 EHYQCFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPA-----------------------------------QSGELP--------SRPIIHIDNGPRLLRACENGDLRSFLEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQLDEQIFKMGLECRWGCDHKLCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLP-QSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLL---SGELSNPTTVCGTPHFMAPEVILADTNG-PYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLFS 1620
E ++ FI AI+ GS LF R+FK EYLER+D + PIHHAC G EIV+LLI+H CDIEA DK RPIH+AC++GH+E LLI CD EA D W +PI+YA R++ +++L H A +SG+ P + IIHI NGP LLRAC+NGDL+ +LN IEYCD+++RRPIHWACE I++V+ LI+ KC+I ARDK +LSPLDIA + +N++LV +++A E L++QI MGL+C+ C+H+LC S+R+K F+KGS+IGSG+FG V+KCKGSGI TVFA+K++ L+ I K IE +I+KF+PKLN++RII+Y+G IQT+ HLCIFMEYL S+E++I + L T++++RYSKQILEGLEFLH IIHRDIKP NIL++ N +K+TDFGVSR L G ++ T GTP+F APEV L G PY SADIWS+GATVINMITG PP P V+ +I + KKL LP S+ MSKEMK FIEKM++PDP++R TA +LL L LFS
Sbjct: 3 EEFKLFINAIKSGSAVLFRRYFKEEYLERKDADLWSPIHHACFAGHAEIVKLLIEHNCDIEALDKWNLRPIHYACYQGHSEAVKLLIEHKCDIEAFDWWNQRPIHYACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHACDQGHSEAVKLLIENKCDIEALDESGDSPMEIAVKSHNERIIHILNGPCLLRACKNGDLKKVSTYLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKSNLSPLDIAIKNQNKELVELLKAEE----LEQQILMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSGGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCGCHPYAVVKKIADTKKLDLPDSQSMSKEMKEFIEKMLDPDPDQRSTAAQLLKLKLFS 566
BLAST of Serine threonine-kinase 25 vs. Planmine SMEST
Match: SMESG000017261.1 (SMESG000017261.1) HSP 1 Score: 530.406 bits (1365), Expect = 0.000e+0 Identity = 272/509 (53.44%), Postives = 362/509 (71.12%), Query Frame = 1
Query: 139 LEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQML--NTHSYSTPAQSGELP--------SRPIIHIDNGPRLLRACENGDLRSFLEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQLDEQIFKMGLECRWGCDHKLCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLP-QSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLL---SGELSNPTTVCGTPHFMAPEVILADTNG-PYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLFS 1620
+E D+ RPIH+AC G E V+LLI+HKCDIEA D RPIH+AC++G +E LLI CD EA+D+W +PI++A ++ +++L N +SG+ P + IIHI NGP LLRAC+NGDL+ +LN IEYCD+++RRPIHWACE I++V+ LI+ KC+I ARDK +LSPLDIA + +N++LV +++A E L++QI MGL+C+ C+H+LC S+R+K F+KGS+IGSG+FG V+KCKGSGI TVFA+K++ L+ I K IE +I+KF+PKLN++RII+Y+G IQT+ HLCIFMEYL S+E++I + L T++++RYSKQILEGLEFLH IIHRDIKP NIL++ N +K+TDFGVSR L G ++ T GTP+F APEV L G PY SADIWS+GATVINMITG PP P V+ +I + KKL LP S+ MSKEMK FIEKM++PDP++R TA +LL L LFS
Sbjct: 128 IEALDVWNLRPIHYACYQGHSEAVKLLIEHKCDIEAFDWWNQRPIHYACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHACDQGHSEAVKLLIENKCDIEALDESGDSPMEIAVKSHNERIIHILNGPCLLRACKNGDLKKVSTYLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKSNLSPLDIAIKNQNKELVELLKAEE----LEQQILMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSGGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCGCHPYAVVKKIADTKKLDLPDSQSMSKEMKEFIEKMLDPDPDQRSTAAQLLKLKLFS 632 HSP 2 Score: 158.688 bits (400), Expect = 1.966e-41 Identity = 98/263 (37.26%), Postives = 138/263 (52.47%), Query Frame = 1
Query: 61 EHYQCFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIE------------ACDKSRW---------------------RPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQSGELPSRPIIHIDNGPRLLRACENGDLRSF-LEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQA 747
E ++ FI AI+ GS LF R+FK EYLER+D + PIHHAC G EIV+LLI+H CDIE ACD+ R RPIH AC++GH+E LLI +CD EA+D W +PI+YA ++ +++L H A RPI + AC G + L + IE DE +RPIH AC++ + V+LLIE KC+I A D+ SP++IA + N+++++I+
Sbjct: 3 EEFKLFINAIKSGSAVLFRRYFKEEYLERKDADLWSPIHHACFAGHAEIVKLLIEHNCDIEALDKRNQRPIHLACDQGRSEAVKLLIEHKCDIEALDKRNRRPIHLACYQGHSEAVKLLIEHNCDIEALDVWNLRPIHYACYQGHSEAVKLLIEHKCDIEAFDW-WNQRPIHY---------ACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHACDQGHSEAVKLLIENKCDIEALDESGDSPMEIAVKSHNERIIHILNG 255 HSP 3 Score: 60.077 bits (144), Expect = 3.432e-9 Identity = 31/82 (37.80%), Postives = 45/82 (54.88%), Query Frame = 1
Query: 73 CFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLL 318
C +RA + G +K + +E D +++RPIH ACE G +++V+ LI KCDI A DKS P+ A + E LL
Sbjct: 257 CLLRACKNGDLKKVSTYLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKSNLSPLDIAIKNQNKELVELL 338
BLAST of Serine threonine-kinase 25 vs. Planmine SMEST
Match: SMESG000017261.1 (SMESG000017261.1) HSP 1 Score: 528.48 bits (1360), Expect = 0.000e+0 Identity = 272/509 (53.44%), Postives = 362/509 (71.12%), Query Frame = 1
Query: 139 LEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQML--NTHSYSTPAQSGELP--------SRPIIHIDNGPRLLRACENGDLRSFLEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQLDEQIFKMGLECRWGCDHKLCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLP-QSIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLL---SGELSNPTTVCGTPHFMAPEVILADTNG-PYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLFS 1620
+E D+ RPIH+AC G E V+LLI+HKCDIEA D RPIH+AC++G +E LLI CD EA+D+W +PI++A ++ +++L N +SG+ P + IIHI NGP LLRAC+NGDL+ +LN IEYCD+++RRPIHWACE I++V+ LI+ KC+I ARDK +LSPLDIA + +N++LV +++A E L++QI MGL+C+ C+H+LC S+R+K F+KGS+IGSG+FG V+KCKGSGI TVFA+K++ L+ I K IE +I+KF+PKLN++RII+Y+G IQT+ HLCIFMEYL S+E++I + L T++++RYSKQILEGLEFLH IIHRDIKP NIL++ N +K+TDFGVSR L G ++ T GTP+F APEV L G PY SADIWS+GATVINMITG PP P V+ +I + KKL LP S+ MSKEMK FIEKM++PDP++R TA +LL L LFS
Sbjct: 227 IEALDVWNLRPIHYACYQGHSEAVKLLIEHKCDIEAFDWWNQRPIHYACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHACDQGHSEAVKLLIENKCDIEALDESGDSPMEIAVKSHNERIIHILNGPCLLRACKNGDLKKVSTYLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKSNLSPLDIAIKNQNKELVELLKAEE----LEQQILMMGLKCKSFCNHRLCNTSLRKKTFDKGSEIGSGAFGHVYKCKGSGIDTVFAVKWIELKKIGVKCIEENINKFLPKLNHQRIIKYFGAIQTEDHLCIFMEYLSGGSLEDEIKRKRSLATENIIRYSKQILEGLEFLHGNNIIHRDIKPDNILMSNGNNIKITDFGVSRSLLRTCGNVTKAETTIGTPNFTAPEVFLTSDEGPPYTVSADIWSLGATVINMITGRPPYCGCHPYAVVKKIADTKKLDLPDSQSMSKEMKEFIEKMLDPDPDQRSTAAQLLKLKLFS 731 HSP 2 Score: 142.895 bits (359), Expect = 9.417e-36 Identity = 95/252 (37.70%), Postives = 130/252 (51.59%), Query Frame = 1
Query: 61 EHYQCFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQSGELPSRPI-------------IHID-----------NGPRLLRACENGDLRSF-LEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNII 741
E ++ FI AI+ GS LF R+FK EYLER+D + PIHHAC G EIV+LLI+H CDIEA DK RPIH AC +G +E LLI CD EA+DK +PI+ A ++ +++L + A RPI + ID N + AC +G + L N IE D RRPIH AC + + V+LLIE C+I A D ++L P+ A + + + V ++
Sbjct: 3 EEFKLFINAIKSGSAVLFRRYFKEEYLERKDADLWSPIHHACFAGHAEIVKLLIEHNCDIEALDKRNQRPIHLACDQGRSEAVKLLIEHKCDIEALDKRNQRPIHLACDQGHSEAVKLLIENKCDIEALDWG-NQRPIHLACYYGHSKAVKLLIDHKCDIEALDWWNQRPIHLACYHGHSEAVKLLIENKCDIEALDWRNRRPIHLACYQGHSEAVKLLIEHNCDIEALDVWNLRPIHYACYQGHSEAVKLL 253 HSP 3 Score: 130.568 bits (327), Expect = 1.135e-31 Identity = 79/204 (38.73%), Postives = 115/204 (56.37%), Query Frame = 1
Query: 139 LEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQSGELPSRPIIHIDNGPRLLRACENGDLRSF-LEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQA 747
+E D +RPIH AC G E V+LLI++KCDIEA D RPIH AC++GH+E LLI +CD EA+D W +PI+YA ++ +++L H A RPI + AC G + L + IE DE +RPIH AC++ + V+LLIE KC+I A D+ SP++IA + N+++++I+
Sbjct: 161 IEALDWWNQRPIHLACYHGHSEAVKLLIENKCDIEALDWRNRRPIHLACYQGHSEAVKLLIEHNCDIEALDVWNLRPIHYACYQGHSEAVKLLIEHKCDIEAFDW-WNQRPIHY---------ACYQGRSEAVKLLIEHKCDIEAIDEWNQRPIHHACDQGHSEAVKLLIENKCDIEALDESGDSPMEIAVKSHNERIIHILNG 354 HSP 4 Score: 58.9214 bits (141), Expect = 6.699e-9 Identity = 31/82 (37.80%), Postives = 45/82 (54.88%), Query Frame = 1
Query: 73 CFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLL 318
C +RA + G +K + +E D +++RPIH ACE G +++V+ LI KCDI A DKS P+ A + E LL
Sbjct: 356 CLLRACKNGDLKKVSTYLNGAAIEYCDKDQRRPIHWACESGNIKVVKSLIKTKCDISARDKSNLSPLDIAIKNQNKELVELL 437
BLAST of Serine threonine-kinase 25 vs. Planmine SMEST
Match: SMESG000032703.1 (SMESG000032703.1) HSP 1 Score: 531.176 bits (1367), Expect = 8.290e-180 Identity = 277/501 (55.29%), Postives = 357/501 (71.26%), Query Frame = 1
Query: 166 RPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPA--QSGELP--------SRPIIHIDNGPRLLRACENGDLRSFLEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQLDEQIFKMGLECRWG-CDHKLCKKSIREKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLEFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLL---SGELSNPTTVCGTPHFMAPEVILADTNG-PYNTSADIWSVGATVINMITGHPPNHKKRPEDVLNEIENDKKLQLPSSELMSKEMKTFIEKMMNPDPNERPTATELLTLSLFS 1620
RPIH C G +E+ +LLIDH CDIEA D+ +RPIHHAC GH ET LLI HCD +A D+ W+PI++A +A +T+++L H + A + G+ P + IIH+ NG RLL AC+ GD + LN +TIEYCD+ KRRPIHWACE I+IV+ LI+ KC+I A+DK +L PLDIA +K+N++LV I++ E +L++QI MGLEC+ C+H+LCK S++ K F KGS+IGSG FG ++KCKGSGI TVFAIK++ L I KYIE +I+ F+PKL ++RII+Y+G IQTK HLCIFMEYL + S+E++I K + T++++RYSKQILEGLEFLH RIIHRDIKPANIL+ EN +KL DFG+SR L GE++ T GTP+F APEVIL NG PY SADIWS+GATVINMITG PP + P V+N I KKL+LP SELMS MK FIE+M+NPDP++R TA +LL L FS
Sbjct: 414 RPIHLTCRSGHIEVSKLLIDHHCDIEAPDELGFRPIHHACRSGHIETVKLLIDHHCDIDASDRNDWQPIHHACVAGNIETLKLLIDHYCNIEALDKFGDSPIEIAVRSCNEGIIHLLNGARLLLACKTGDTKKVSRLLNSITIEYCDKGKRRPIHWACESGNIKIVKSLIKTKCDITAKDKDNLRPLDIAIKKENKELVEILK----EEELEQQISMMGLECKPPFCNHRLCKTSLKNKTFAKGSEIGSGGFGHIYKCKGSGIDTVFAIKWIELIKISEKYIEENINTFLPKLMHKRIIRYFGAIQTKDHLCIFMEYLFKGSLEDEIEKKRFIATKNIIRYSKQILEGLEFLHGNRIIHRDIKPANILMGPENNIKLADFGISRSLMRTCGEITKAVTTIGTPNFTAPEVILTSDNGPPYTESADIWSMGATVINMITGRPPYYYCHPFAVINRISTSKKLELPESELMSDAMKGFIEEMLNPDPDQRSTAAQLLKLKFFS 910 HSP 2 Score: 126.331 bits (316), Expect = 3.383e-30 Identity = 77/227 (33.92%), Postives = 118/227 (51.98%), Query Frame = 1
Query: 139 LEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQML-------------NTHSYSTPAQSGELPSRPII---HID-NGPRLL------RACENGDLRSF-LEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQA 747
+ D+N RPIH A G +E ++LLIDH CDIE D+ + RPIH AC GH ET LLI HCD +A+D+ ++PI++A T+ +++L N +SG + ++ H D P L AC +G + + L + I+ D N +PIH AC I+ ++LLI+ CNI A DK+ SP++IA R N+ +++++
Sbjct: 306 INASDMNDNRPIHFALRAGHIETMKLLIDHHCDIEVFDRHKQRPIHLACIAGHIETMKLLIYHHCDIDALDQNDYRPIHFALREGHTEAVKLLIDYHCDVDAPDKWNIRPIHLTCRSGHIEVSKLLIDHHCDIEAPDELGFRPIHHACRSGHIETVKLLIDHHCDIDASDRNDWQPIHHACVAGNIETLKLLIDHYCNIEALDKFGDSPIEIAVRSCNEGIIHLLNG 532 HSP 3 Score: 120.939 bits (302), Expect = 1.954e-28 Identity = 94/278 (33.81%), Postives = 132/278 (47.48%), Query Frame = 1
Query: 64 HYQCFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQSGELPSRPII------HI-------------------DNGP--RLLRACENGDLRSFLEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQLDEQ--IFKMGLECRWG 810
H+ C I +I L ++ E L+ D R IHHAC G +E ++LLIDH CDIEA D R IH AC GH E LLI HCD EA+D+ W+PI+YA A K +++L + A S RPI HI DN P LRA ++ ++ D IE D +K+RPIH AC I+ ++LLI C+I A D+ D P+ A R+ + + V ++ ++ ++ I + L CR G
Sbjct: 153 HFACIAGHIETVNI-LIKEYYNIEILDGFDW---RLIHHACSAGHIETMKLLIDHHCDIEAFDWRNKRSIHLACSAGHIEAVKLLIYHHCDIEALDQNDWRPIHYACCAGHMKIVKLLIDYHCDIDA-SDTNDWRPIHLACGAGHIEIVKLLIDYHCDINASDMNDNRPIHFALRAGHIETMKLLIDHHCD--IEVFDRHKQRPIHLACIAGHIETMKLLIYHHCDIDALDQNDYRPIHFALREGHTEAVKLLIDYHCDVDAPDKWNIRPIHLTCRSG 423 HSP 4 Score: 120.939 bits (302), Expect = 2.275e-28 Identity = 74/221 (33.48%), Postives = 114/221 (51.58%), Query Frame = 1
Query: 151 DLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYST-------------PAQSGELPSRPII---HID-------NGPRLLRACENGDLRSF-LEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNII 741
D + ++PIHH C VE V+LLIDH CDIE+ D S RPIHHAC G E LLI HC+ +A+ K+ +PI++A +A +T+ +L Y+ +G + + ++ H D N + AC G + + L + IE D+N RPIH+AC ++IV+LLI+ C+I A D D P+ +A + ++V ++
Sbjct: 79 DRSNRQPIHHTCNARHVETVKLLIDHHCDIESLDNSGGRPIHHACIGGCMEVVKLLIDHHCNIDALGKYDQRPIHFACIAGHIETVNILIKEYYNIEILDGFDWRLIHHACSAGHIETMKLLIDHHCDIEAFDWRNKRSIHLACSAGHIEAVKLLIYHHCDIEALDQNDWRPIHYACCAGHMKIVKLLIDYHCDIDASDTNDWRPIHLACGAGHIEIVKLL 299 HSP 5 Score: 120.168 bits (300), Expect = 3.317e-28 Identity = 83/254 (32.68%), Postives = 129/254 (50.79%), Query Frame = 1
Query: 58 SEHYQCFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEGHTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQSGELPSRPIIHIDNGPRLLRACENGDLRSF-LEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNIIQARETEMQL-DEQIFK-MGLECRWG 810
S H C I + ++H +E D N RPIH+AC G ++IV+LLID+ CDI+A D + WRPIH AC GH E LLI HCD A D +PI++A A +T+++L H RPI H+ AC G + + L + I+ D+N RPIH+A + + V+LLI+ C++ A DK+++ P+ + R + ++ ++ +++ DE F+ + CR G
Sbjct: 217 SIHLACSAGHIEAVKLLIYHHC----DIEALDQNDWRPIHYACCAGHMKIVKLLIDYHCDIDASDTNDWRPIHLACGAGHIEIVKLLIDYHCDINASDMNDNRPIHFALRAGHIETMKLLIDHHCDIEVFDRH-KQRPI-HL--------ACIAGHIETMKLLIYHHCDIDALDQNDYRPIHFALREGHTEAVKLLIDYHCDVDAPDKWNIRPIHLTCRSGHIEVSKLLIDHHCDIEAPDELGFRPIHHACRSG 456 HSP 6 Score: 106.301 bits (264), Expect = 9.331e-24 Identity = 81/266 (30.45%), Postives = 114/266 (42.86%), Query Frame = 1
Query: 166 RPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPIHHACWEG-------------------------------------------------HTETASLLICRHCDSEAMDKWGWKPINYASMARRTKTIQMLNTHSYSTPAQSGELPSRPII------HIDNGPRLLR------------------ACENGDLRSF-LEFLNDVTIEYCDENKRRPIHWACEKEKIQIVQLLIERKCNIFARDKYDLSPLDIAKRKKNQKLVNII 741
RPIHHAC Q+EIV+LLID+ C+IEA D+S WRPIHHAC G H ET LLI HCD E++D G +PI++A + + +++L H + A G+ RPI HI+ L++ AC G + + L + IE D +R IH AC I+ V+LLI C+I A D+ D P+ A + K+V ++
Sbjct: 2 RPIHHACSENQIEIVKLLIDYHCNIEASDESNWRPIHHACSAGNTEAVKLLINCHPSIWVLDGSEWPIIQRVCEKPLDRSNRQPIHHTCNARHVETVKLLIDHHCDIESLDNSGGRPIHHACIGGCMEVVKLLIDHHCNIDAL-GKYDQRPIHFACIAGHIETVNILIKEYYNIEILDGFDWRLIHHACSAGHIETMKLLIDHHCDIEAFDWRNKRSIHLACSAGHIEAVKLLIYHHCDIEALDQNDWRPIHYACCAGHMKIVKLL 266 HSP 7 Score: 52.7582 bits (125), Expect = 7.420e-7 Identity = 28/66 (42.42%), Postives = 36/66 (54.55%), Query Frame = 1
Query: 76 FIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQVEIVRLLIDHKCDIEACDKSRWRPI 273
+ A + G K R +E D K+RPIH ACE G ++IV+ LI KCDI A DK RP+
Sbjct: 535 LLLACKTGDTKKVSRLLNSITIEYCDKGKRRPIHWACESGNIKIVKSLIKTKCDITAKDKDNLRPL 600 The following BLAST results are available for this feature:
BLAST of Serine threonine-kinase 25 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine threonine-kinase 25 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033787 ID=SMED30033787|Name=Serine threonine-kinase 25|organism=Schmidtea mediterranea sexual|type=transcript|length=1687bpback to top protein sequence of SMED30033787-orf-1 >SMED30033787-orf-1 ID=SMED30033787-orf-1|Name=SMED30033787-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=525bp MSNSEHYQCFIRAIRGGSIKLFHRFFKREYLEREDLNKKRPIHHACECGQback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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