Paired amphipathic helix protein Sin3a
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033761 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Human
Match: SIN3A (SIN3 transcription regulator family member A [Source:HGNC Symbol;Acc:HGNC:19353]) HSP 1 Score: 176.407 bits (446), Expect = 1.861e-44 Identity = 185/735 (25.17%), Postives = 319/735 (43.40%), Query Frame = 1
Query: 4 DSEAYDLSKFNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
DS D SK + F+K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + + N L Y +A ++ CF +FI+ +G +L I+++D
Sbjct: 449 DSSMADASKHGGGTESL------FFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLETYPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EICVQVTDLYLAENNNGATGGQLNTQNSRSLLEST--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTIELLD 1083
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Human
Match: SIN3A (SIN3 transcription regulator family member A [Source:HGNC Symbol;Acc:HGNC:19353]) HSP 1 Score: 176.407 bits (446), Expect = 1.861e-44 Identity = 185/735 (25.17%), Postives = 319/735 (43.40%), Query Frame = 1
Query: 4 DSEAYDLSKFNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
DS D SK + F+K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + + N L Y +A ++ CF +FI+ +G +L I+++D
Sbjct: 449 DSSMADASKHGGGTESL------FFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLETYPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EICVQVTDLYLAENNNGATGGQLNTQNSRSLLEST--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTIELLD 1083
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Human
Match: SIN3A (SIN3 transcription regulator family member A [Source:HGNC Symbol;Acc:HGNC:19353]) HSP 1 Score: 176.407 bits (446), Expect = 1.861e-44 Identity = 185/735 (25.17%), Postives = 319/735 (43.40%), Query Frame = 1
Query: 4 DSEAYDLSKFNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
DS D SK + F+K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + + N L Y +A ++ CF +FI+ +G +L I+++D
Sbjct: 449 DSSMADASKHGGGTESL------FFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLETYPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EICVQVTDLYLAENNNGATGGQLNTQNSRSLLEST--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTIELLD 1083
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Human
Match: SIN3B (SIN3 transcription regulator family member B [Source:HGNC Symbol;Acc:HGNC:19354]) HSP 1 Score: 167.548 bits (423), Expect = 1.083e-41 Identity = 105/326 (32.21%), Postives = 174/326 (53.37%), Query Frame = 1
Query: 37 SNLSKIG-LEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEK------KDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
+ + K G L+ F+K+++ L + + CI LFN + EL + L ++P L+ F + + +++ ++ SC I G SYR LP Y KCSGR IC + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ M+ E++ KF+LDD++GG+S ++ R+AIYRIYGD +IE LK P A+P+V+ R++ K +EW + F +W ++ K Y +SLD+Q ++ + D+ L+ + ++I+S+
Sbjct: 297 AAVGKYGTLQEFSFFDKVRRVLKSQE------VYENFLRCIALFNQELVSGSELLQLVSPFLG-KFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRI-------------GSSYRALPKTYQQPKCSGRT--AICKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESV 599
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Human
Match: SIN3B (SIN3 transcription regulator family member B [Source:HGNC Symbol;Acc:HGNC:19354]) HSP 1 Score: 150.984 bits (380), Expect = 1.898e-36 Identity = 105/356 (29.49%), Postives = 175/356 (49.16%), Query Frame = 1
Query: 37 SNLSKIG-LEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEK------KDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNL---------------------KICHDC---------LNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
+ + K G L+ F+K+++ L + + CI LFN + EL + L ++P L+ F + + +++ ++ SC I G SYR LP Y KCSGR + K + C LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ M+ E++ KF+LDD++GG+S ++ R+AIYRIYGD +IE LK P A+P+V+ R++ K +EW + F +W ++ K Y +SLD+Q ++ + D+ L+ + ++I+S+
Sbjct: 297 AAVGKYGTLQEFSFFDKVRRVLKSQE------VYENFLRCIALFNQELVSGSELLQLVSPFLG-KFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRI-------------GSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESV 631
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Celegans
Match: sin-3 (Paired amphipathic helix protein sin-3 [Source:UniProtKB/Swiss-Prot;Acc:A5JYW9]) HSP 1 Score: 73.559 bits (179), Expect = 6.386e-13 Identity = 65/268 (24.25%), Postives = 120/268 (44.78%), Query Frame = 1
Query: 136 THLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLR-------------FSFNDGGPSYRLLPSDYNHKKCSGRKNLKI-CHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKH 897
+HL I + + I +L + + ++ L +Q++ ++ N EN+ R I+ ++ LR + GPSYR + D CSGR L LN+ + PS SEDT + + KK+ EE K EDERYE+D+ + N+ ++ L + + E+MS E+K F+LD + SS + + +++ ++ + I+ + P + + ++ ++EK W++ W D +K
Sbjct: 708 SHLMVLINAYANLDITREQLISELPKIMGTSGSDLEMIILQLLGAEKEPKNRPENDMDAVMRKDLPAIQPKRGLRDQKMLQQVKNVEAATVCTLGPSYRFM-KDTKATDCSGRVELDDDLKGVLNDTWTSIPSWSSEDTGSQAIKKSNLEEFHFKTEDERYELDIIVDSNRTVIEQLSKTLRDYEAMSDEDKKSFKLDKWLNASSRSTTIRVLAKVFTNSAQDFIDAAQKNPLVGLRRILESLKEKDLLWSRFQQDTNRTWRDALDKQ 974
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Celegans
Match: sin-3 (Paired amphipathic helix protein sin-3 [Source:UniProtKB/Swiss-Prot;Acc:A5JYW9]) HSP 1 Score: 73.559 bits (179), Expect = 6.497e-13 Identity = 65/268 (24.25%), Postives = 120/268 (44.78%), Query Frame = 1
Query: 136 THLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLR-------------FSFNDGGPSYRLLPSDYNHKKCSGRKNLKI-CHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKH 897
+HL I + + I +L + + ++ L +Q++ ++ N EN+ R I+ ++ LR + GPSYR + D CSGR L LN+ + PS SEDT + + KK+ EE K EDERYE+D+ + N+ ++ L + + E+MS E+K F+LD + SS + + +++ ++ + I+ + P + + ++ ++EK W++ W D +K
Sbjct: 708 SHLMVLINAYANLDITREQLISELPKIMGTSGSDLEMIILQLLGAEKEPKNRPENDMDAVMRKDLPAIQPKRGLRDQKMLQQVKNVEAATVCTLGPSYRFM-KDTKATDCSGRVELDDDLKGVLNDTWTSIPSWSSEDTGSQAIKKSNLEEFHFKTEDERYELDIIVDSNRTVIEQLSKTLRDYEAMSDEDKKSFKLDKWLNASSRSTTIRVLAKVFTNSAQDFIDAAQKNPLVGLRRILESLKEKDLLWSRFQQDTNRTWRDALDKQ 974
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Fly
Match: Sin3A (gene:FBgn0022764 transcript:FBtr0339651) HSP 1 Score: 155.221 bits (391), Expect = 5.689e-38 Identity = 107/339 (31.56%), Postives = 175/339 (51.62%), Query Frame = 1
Query: 31 FNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHL---YYDFI--------------QIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSF-NDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
F+ SK + F+K+++ L YD + C+ LFN + EL + L ++P L + DF+ + Q+ S N D + E +D+ S G SY LP KKCSGR L C + LN++++ FP+ SED++ V+S+K EE I + EDER+E+D+ E+N ++ L + KKM MS EE KF LDD++GG+S + ++AI+RIYGD + +I G+K P +A+P+V+ R++ K +EW + F W ++ K+Y +SLD+Q ++ D L+ + F++I++L
Sbjct: 910 FSEASSKCTISDAAFFDKVRKALRSPEV--YD----NFLRCLTLFNQEIVSKTELLGLVSPFL-MKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTAL--CREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETL 1239
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Fly
Match: Sin3A (gene:FBgn0022764 transcript:FBtr0087889) HSP 1 Score: 155.221 bits (391), Expect = 6.319e-38 Identity = 107/339 (31.56%), Postives = 175/339 (51.62%), Query Frame = 1
Query: 31 FNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHL---YYDFI--------------QIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSF-NDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
F+ SK + F+K+++ L YD + C+ LFN + EL + L ++P L + DF+ + Q+ S N D + E +D+ S G SY LP KKCSGR L C + LN++++ FP+ SED++ V+S+K EE I + EDER+E+D+ E+N ++ L + KKM MS EE KF LDD++GG+S + ++AI+RIYGD + +I G+K P +A+P+V+ R++ K +EW + F W ++ K+Y +SLD+Q ++ D L+ + F++I++L
Sbjct: 910 FSEASSKCTISDAAFFDKVRKALRSPEV--YD----NFLRCLTLFNQEIVSKTELLGLVSPFL-MKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTAL--CREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETL 1239
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Fly
Match: Sin3A (gene:FBgn0022764 transcript:FBtr0087887) HSP 1 Score: 155.221 bits (391), Expect = 7.177e-38 Identity = 107/339 (31.56%), Postives = 175/339 (51.62%), Query Frame = 1
Query: 31 FNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHL---YYDFI--------------QIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSF-NDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
F+ SK + F+K+++ L YD + C+ LFN + EL + L ++P L + DF+ + Q+ S N D + E +D+ S G SY LP KKCSGR L C + LN++++ FP+ SED++ V+S+K EE I + EDER+E+D+ E+N ++ L + KKM MS EE KF LDD++GG+S + ++AI+RIYGD + +I G+K P +A+P+V+ R++ K +EW + F W ++ K+Y +SLD+Q ++ D L+ + F++I++L
Sbjct: 910 FSEASSKCTISDAAFFDKVRKALRSPEV--YD----NFLRCLTLFNQEIVSKTELLGLVSPFL-MKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTAL--CREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETL 1239
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Fly
Match: Sin3A (gene:FBgn0022764 transcript:FBtr0303565) HSP 1 Score: 155.221 bits (391), Expect = 7.177e-38 Identity = 107/339 (31.56%), Postives = 175/339 (51.62%), Query Frame = 1
Query: 31 FNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHL---YYDFI--------------QIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSF-NDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
F+ SK + F+K+++ L YD + C+ LFN + EL + L ++P L + DF+ + Q+ S N D + E +D+ S G SY LP KKCSGR L C + LN++++ FP+ SED++ V+S+K EE I + EDER+E+D+ E+N ++ L + KKM MS EE KF LDD++GG+S + ++AI+RIYGD + +I G+K P +A+P+V+ R++ K +EW + F W ++ K+Y +SLD+Q ++ D L+ + F++I++L
Sbjct: 910 FSEASSKCTISDAAFFDKVRKALRSPEV--YD----NFLRCLTLFNQEIVSKTELLGLVSPFL-MKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTAL--CREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETL 1239
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Fly
Match: Sin3A (gene:FBgn0022764 transcript:FBtr0087890) HSP 1 Score: 155.221 bits (391), Expect = 7.177e-38 Identity = 107/339 (31.56%), Postives = 175/339 (51.62%), Query Frame = 1
Query: 31 FNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHL---YYDFI--------------QIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSF-NDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
F+ SK + F+K+++ L YD + C+ LFN + EL + L ++P L + DF+ + Q+ S N D + E +D+ S G SY LP KKCSGR L C + LN++++ FP+ SED++ V+S+K EE I + EDER+E+D+ E+N ++ L + KKM MS EE KF LDD++GG+S + ++AI+RIYGD + +I G+K P +A+P+V+ R++ K +EW + F W ++ K+Y +SLD+Q ++ D L+ + F++I++L
Sbjct: 910 FSEASSKCTISDAAFFDKVRKALRSPEV--YD----NFLRCLTLFNQEIVSKTELLGLVSPFL-MKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTAL--CREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETL 1239
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Zebrafish
Match: sin3b (SIN3 transcription regulator family member B [Source:ZFIN;Acc:ZDB-GENE-030131-8264]) HSP 1 Score: 183.726 bits (465), Expect = 5.505e-47 Identity = 185/750 (24.67%), Postives = 323/750 (43.07%), Query Frame = 1
Query: 73 LFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNS---------ENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGY-----FFGTPG--IEISEFPSGSVKEQ---------KKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFN-EDLQSRHVK-----YNLMIGNSYMYTLLRLVHVLIDRLSALKI----------HSIKMSQE-----------DSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGR--LLIQMIDPDNIK 2151
F+K+++ L + + CI LFN + EL + L ++P LY F + K++++ E ++ SC + G SYR LP Y KCSGR IC + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ +S E++ +F+LDD +GG+S ++ R+A+YRIYGD +IEGLK P A+P+V+ R++ K +EW + F +W ++ K Y +SLD+QG ++ + D L+ + N+I SIY+ Q++ G G + + PH+ + ED I+ D SLI H+ + K+D+ D+I +++ + FF G E EF + + + + + R+ +C + + +S V + + + D ++ H K YNL N+ Y LRL L RL LKI H + ++E +D + S E++ Y ++ S + S ++ +R ++ A++ FTI +LIQ I + Q ++ + E + +LY K +G G+++++ + Y +A + CF +FI+ +G+ L I+++D + +
Sbjct: 353 FFDKVRRLLKSQE------VYENFLRCIALFNQEVVSGAELLQLVTPFLG-KFPELYTQFKSFLG--DKELSHVISGLSDRYMEGGGREVDYASCKRL-------------GSSYRALPKTYQQPKCSGR--TAICKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRLSLEDQERFRLDDCLGGTSEVIQRRAVYRIYGDKAPEIIEGLKRSPATAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQGVNFKQNDMKALRSKSLL----------------------------NEIESIYDER-QEQSTEEGSVGQQGRDGTSTASTSEPHMIF---------------NYEDKQILEDAASLIIYHVKRQPTIHKDDK----DHIKRIIQHFAPDLFFARRGELSETEEFTDEEGEGEDGAAAGGGVSSTGQQQLNGESRRRRCTSPQSMD-------TSTVAHSINPEGEAVDLRDPEAEHQKEMDGVYNLFFVNNNWYFFLRLHQTLCSRL--LKIYRQAERQLLEHRAEQNRERLLMGEGRREKANDLAMELRLKQPSEVELEEYYPAFLDMVRSLLDGNLESTQYEDTLREMFTIHAYIGFTIDKLIQNIVRQLQHLVSD--EVCLQVTELYLAERKRGAAG--GNLSSQCVRAAWEASYQWKAERVMAEEN--CFKVMFIQNKGQVTLTIELLDTEEAQ 1014
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Zebrafish
Match: sin3aa (SIN3 transcription regulator family member Aa [Source:ZFIN;Acc:ZDB-GENE-070620-3]) HSP 1 Score: 177.948 bits (450), Expect = 3.835e-45 Identity = 190/716 (26.54%), Postives = 326/716 (45.53%), Query Frame = 1
Query: 73 LFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKED----RQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQED--------------SDFDXXXXXXXXXXXXI-----DRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
F K+++ L + + YD + C+ +FN+ I EL + L ++P L+ F + K++++ E K+ + I + D S G SYR LP Y KC+GR IC + LN+ ++ FPS SED++ VSSKK +EE + + EDER+E+D+ E N ++ L KK+ MS EE+ KF+LD+ +GG S I+ RKAI RIYGD ++I+GLK P ++P+V+ R++ K +EW + F +W ++ K+Y +SLD+QG ++ + D+ L+ T ++I+S I + + NS + T PHLTL + ED I+ D +LI +H+ S+++KED +Q++ +I +L F G+ +S+ +E + D A + H +K FS+ + + L+S YNL N+ Y LRL +L RL L + + +ED D + + + E + D Y+ L ++ + + N +AS ++ +R ++ A++ FT+ +LIQ IA+ Q I+ E + +LY + S S T GS+ + Y +A ++ CF +F++ G +L ++++D
Sbjct: 469 FFEKVRKVLRSAEA--YD----NFLRCLVIFNEEIISRAELVQLVVPFLG-KFPELFTWFKNFLG--YKEMSHLETYPKER---ATEGIAMEIDYA-SCKRLGSSYRALPKSYQLPKCTGR--TAICKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHMYRCEDERFELDVVLETNLATIRVLETTQKKLSRMSAEEQAKFRLDNTLGGFSEIIHRKAIQRIYGDKAPDIIDGLKKNPAASVPIVLKRLKLKEEEWREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKVLRSKTLLNEIES-------------------------IFDERQEQVSEDNS--------------STTASSPHLTL---------------TYEDHQILEDAAALIIHHVKRQSSINKEDKYKIKQIVYHFIPDML---FAQRGV-LSDVEEEDEEEDMELDEGA----------SKKHNGLAGGASASPTKSKLLFSA---STAQRLRSCEDAYNLFYVNNNWYIFLRLHQILCSRLLRLYAQAERQIEEDMREREWEREVLGLKRDKNENTAVQLRLKEPMDVEVEDYYSAFLEMVRNLLDGNMEAS-QYEDSLREMFTIHAYIAFTMDKLIQNIARQLQHIVSE--EICVQVTELYLVESGH--SSTGGSLLTQSSRAQAEASYQRKAEQLMSDEN--CFKLMFLKSRGNVQLTVELLD 1090
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Zebrafish
Match: sin3ab (SIN3 transcription regulator family member Ab [Source:ZFIN;Acc:ZDB-GENE-030131-2066]) HSP 1 Score: 176.407 bits (446), Expect = 1.371e-44 Identity = 190/734 (25.89%), Postives = 323/734 (44.01%), Query Frame = 1
Query: 37 SNLSKIGLEVVKLF-NKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEV--GPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKED----RQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIH---------------------SIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNL---LIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
+ SK+G+ LF K+++ L S + YD + C+ +FN I EL + L ++P L+ F + + S +++ I+ EI+ R G SYR LP + +C+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L V K++ MS EE+ KF+LD+ IGGSS ++ RKAI RIYGD ++I+GLK P +++P+V+ R++ K +EW + F +W ++ K+Y +SLD+QG ++ + D+ + T ++I++L Y E + V GPH+TL+ DS I+ D +LI +H+ S + K+D +Q++ +I +L G E + ++ + + T T K K +HT +Q L S YNL N+ Y LRL ++L RL L+I+ +K + DS E E D Y+ L + L+D N S ++++R ++ A++ FT+ +LIQ I + Q I+ + + + DLY S+ T GS++ + Y ++ ++ CF +F + +G +L ++++D
Sbjct: 449 AEASKLGIGAESLFFEKVRKALRSSEA--YD----NFLRCLVIFNQEVISRAELVQLVLPFLG-KFPELFTWFKNFLGYRECAHIESFPKERATEGIAM-EIDYASCKRL-----GSSYRALPKSFQQPRCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAVQKRISRMSAEEQAKFRLDNTIGGSSEVIHRKAIQRIYGDKAPDIIDGLKTNPAVSVPIVLKRLKIKEEEWREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKVFRSKTLLNEIETL------------------------------------------YDERQEQASEDNAAVPSGPHMTLMY-EDS------------QILEDAAALIIHHVKRQSGIHKDDKYKIKQIIYHFIPDMLFARRGELSDVEEEDEEETEPDEDGTKKHNGT-TSSKSKLLFSHTAASQQ---------------------KLSSCDDAYNLFFVNNNWYIFLRLHYILCSRL--LRIYGQAEKQIEEDTREREWERNVLGLKREKNDSPAIQLRLKEPMDIEVEDYYSAFLEMVRNLLDGNMETSQ----YEDQLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDDI--CVQVTDLYL--SECANKATGGSLSTQSSRSNAETSYQRKSEQLMSDEN--CFKLLFQKSKGTVQLAVELLD 1077
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Zebrafish
Match: sin3ab (SIN3 transcription regulator family member Ab [Source:ZFIN;Acc:ZDB-GENE-030131-2066]) HSP 1 Score: 176.407 bits (446), Expect = 1.371e-44 Identity = 190/734 (25.89%), Postives = 323/734 (44.01%), Query Frame = 1
Query: 37 SNLSKIGLEVVKLF-NKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEV--GPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKED----RQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIH---------------------SIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNL---LIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
+ SK+G+ LF K+++ L S + YD + C+ +FN I EL + L ++P L+ F + + S +++ I+ EI+ R G SYR LP + +C+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L V K++ MS EE+ KF+LD+ IGGSS ++ RKAI RIYGD ++I+GLK P +++P+V+ R++ K +EW + F +W ++ K+Y +SLD+QG ++ + D+ + T ++I++L Y E + V GPH+TL+ DS I+ D +LI +H+ S + K+D +Q++ +I +L G E + ++ + + T T K K +HT +Q L S YNL N+ Y LRL ++L RL L+I+ +K + DS E E D Y+ L + L+D N S ++++R ++ A++ FT+ +LIQ I + Q I+ + + + DLY S+ T GS++ + Y ++ ++ CF +F + +G +L ++++D
Sbjct: 449 AEASKLGIGAESLFFEKVRKALRSSEA--YD----NFLRCLVIFNQEVISRAELVQLVLPFLG-KFPELFTWFKNFLGYRECAHIESFPKERATEGIAM-EIDYASCKRL-----GSSYRALPKSFQQPRCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAVQKRISRMSAEEQAKFRLDNTIGGSSEVIHRKAIQRIYGDKAPDIIDGLKTNPAVSVPIVLKRLKIKEEEWREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKVFRSKTLLNEIETL------------------------------------------YDERQEQASEDNAAVPSGPHMTLMY-EDS------------QILEDAAALIIHHVKRQSGIHKDDKYKIKQIIYHFIPDMLFARRGELSDVEEEDEEETEPDEDGTKKHNGT-TSSKSKLLFSHTAASQQ---------------------KLSSCDDAYNLFFVNNNWYIFLRLHYILCSRL--LRIYGQAEKQIEEDTREREWERNVLGLKREKNDSPAIQLRLKEPMDIEVEDYYSAFLEMVRNLLDGNMETSQ----YEDQLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDDI--CVQVTDLYL--SECANKATGGSLSTQSSRSNAETSYQRKSEQLMSDEN--CFKLLFQKSKGTVQLAVELLD 1077
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Xenopus
Match: sin3b (SIN3 transcription regulator family member B [Source:NCBI gene;Acc:779742]) HSP 1 Score: 192.971 bits (489), Expect = 7.417e-50 Identity = 190/741 (25.64%), Postives = 325/741 (43.86%), Query Frame = 1
Query: 37 SNLSKIG-LEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDF--------IQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLG-YFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQ----------EDSDFDXXXXXXXXXXXXI-----------DRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGR--LLIQMIDPDNIK 2151
+++ K G L+ FNK+++ L + + CI LFN + EL + L ++P L+ F + + + D +N E ++ SC I G SYR LP + H KCSGR L C + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ MS E++ KF+LDD +GG+S ++ R+AIYRIYGD +++E LK P A+P+V+ R++ K +EW + F +W ++ + Y +SLD+Q ++ + D+ L+ + N+I S+Y+ Q R T GPHL + ED I+ D +LIT ++ + KED+ + + Q L FF + S + + ++ +L +R T E E V T +E Y+L N+ Y LRL H L RL LKI+ Q E FD N + E+ + Y L+++ + N D + ++ +R ++ A++ FTI +L+Q I + ++ + E +++LY K +G GS+A++ + K Y +A + C+ CF +F++++G+ + I+++D ++++
Sbjct: 293 ASVGKYGTLQEFSFFNKVRRVLKSQE------VYENFLRCIALFNQELVSGSELLQLVTPFLG-KFPELFAQFKSFLGVKELSFASPVTNDRSN-EGIGREIDYASCKRI-------------GSSYRALPKSFPHPKCSGRTAL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMSPEDQEKFRLDDRLGGTSEVIQRRAIYRIYGDKAPDIVESLKKNPVTAVPVVLKRLKAKEEEWREAQRGFNKIWREQYERAYLKSLDHQAVNFKQNDTKALRSKSLL----------------------------NEIESVYDERQEQQPDGR------------TTTSSGPHLIY---------------TYEDWQILEDAAALITFYVNRQPTIQKEDKDTIWQVLHQFLPELFFSSSSSSPSCQSLFAASADEGPTETVTESSVTELPERRRKTVTTEVAQEPPPPVETPHEPPPKTIDE-------VYSLFYTNNNWYFFLRLHHTLCSRL--LKIYRQAQQQLMEYRTEKEREKRLFDGRRDRSNGPAMELRLKQPSEVELEEYYPAFLDMVRNLFIGNLDPT-HYEDTLREMFTIHAYIVFTIDKLVQNITRQLHHLVSD--EICLKVVELYLSEKKRGAAG--GSLASQCVRAAKEASYQWKA-EHCMTDEN-CFKMMFLQRQGQVTMTIELLDTEDVQ 938
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Xenopus
Match: sin3b (SIN3 transcription regulator family member B [Source:NCBI gene;Acc:779742]) HSP 1 Score: 192.971 bits (489), Expect = 9.414e-50 Identity = 190/741 (25.64%), Postives = 325/741 (43.86%), Query Frame = 1
Query: 37 SNLSKIG-LEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDF--------IQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLG-YFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQ----------EDSDFDXXXXXXXXXXXXI-----------DRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGR--LLIQMIDPDNIK 2151
+++ K G L+ FNK+++ L + + CI LFN + EL + L ++P L+ F + + + D +N E ++ SC I G SYR LP + H KCSGR L C + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ MS E++ KF+LDD +GG+S ++ R+AIYRIYGD +++E LK P A+P+V+ R++ K +EW + F +W ++ + Y +SLD+Q ++ + D+ L+ + N+I S+Y+ Q R T GPHL + ED I+ D +LIT ++ + KED+ + + Q L FF + S + + ++ +L +R T E E V T +E Y+L N+ Y LRL H L RL LKI+ Q E FD N + E+ + Y L+++ + N D + ++ +R ++ A++ FTI +L+Q I + ++ + E +++LY K +G GS+A++ + K Y +A + C+ CF +F++++G+ + I+++D ++++
Sbjct: 297 ASVGKYGTLQEFSFFNKVRRVLKSQE------VYENFLRCIALFNQELVSGSELLQLVTPFLG-KFPELFAQFKSFLGVKELSFASPVTNDRSN-EGIGREIDYASCKRI-------------GSSYRALPKSFPHPKCSGRTAL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMSPEDQEKFRLDDRLGGTSEVIQRRAIYRIYGDKAPDIVESLKKNPVTAVPVVLKRLKAKEEEWREAQRGFNKIWREQYERAYLKSLDHQAVNFKQNDTKALRSKSLL----------------------------NEIESVYDERQEQQPDGR------------TTTSSGPHLIY---------------TYEDWQILEDAAALITFYVNRQPTIQKEDKDTIWQVLHQFLPELFFSSSSSSPSCQSLFAASADEGPTETVTESSVTELPERRRKTVTTEVAQEPPPPVETPHEPPPKTIDE-------VYSLFYTNNNWYFFLRLHHTLCSRL--LKIYRQAQQQLMEYRTEKEREKRLFDGRRDRSNGPAMELRLKQPSEVELEEYYPAFLDMVRNLFIGNLDPT-HYEDTLREMFTIHAYIVFTIDKLVQNITRQLHHLVSD--EICLKVVELYLSEKKRGAAG--GSLASQCVRAAKEASYQWKA-EHCMTDEN-CFKMMFLQRQGQVTMTIELLDTEDVQ 942
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Xenopus
Match: sin3b (SIN3 transcription regulator family member B [Source:NCBI gene;Acc:779742]) HSP 1 Score: 192.586 bits (488), Expect = 9.859e-50 Identity = 192/751 (25.57%), Postives = 326/751 (43.41%), Query Frame = 1
Query: 37 SNLSKIG-LEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDF--------IQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTP-----------GIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQ----------EDSDFDXXXXXXXXXXXXI-----------DRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGR--LLIQMIDPDNIK 2151
+++ K G L+ FNK+++ L + + CI LFN + EL + L ++P L+ F + + + D +N E ++ SC I G SYR LP + H KCSGR L C + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ MS E++ KF+LDD +GG+S ++ R+AIYRIYGD +++E LK P A+P+V+ R++ K +EW + F +W ++ + Y +SLD+Q ++ + D+ L+ + N+I S+Y+ Q R T GPHL + ED I+ D +LIT ++ + KED+ + + Q L F + E P+ +V E ++ L +R T E E V T +E Y+L N+ Y LRL H L RL LKI+ Q E FD N + E+ + Y L+++ + N D + ++ +R ++ A++ FTI +L+Q I + ++ + E +++LY K +G GS+A++ + K Y +A + C+ CF +F++++G+ + I+++D ++++
Sbjct: 298 ASVGKYGTLQEFSFFNKVRRVLKSQE------VYENFLRCIALFNQELVSGSELLQLVTPFLG-KFPELFAQFKSFLGVKELSFASPVTNDRSN-EGIGREIDYASCKRI-------------GSSYRALPKSFPHPKCSGRTAL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMSPEDQEKFRLDDRLGGTSEVIQRRAIYRIYGDKAPDIVESLKKNPVTAVPVVLKRLKAKEEEWREAQRGFNKIWREQYERAYLKSLDHQAVNFKQNDTKALRSKSLL----------------------------NEIESVYDERQEQQPDGR------------TTTSSGPHLIY---------------TYEDWQILEDAAALITFYVNRQPTIQKEDKDTIWQVLHQFLPELFFSSSSSSPSCQSLFAASADEGPTETVTESSVTE----------LPERRRKTVTTEVAQEPPPPVETPHEPPPKTIDE-------VYSLFYTNNNWYFFLRLHHTLCSRL--LKIYRQAQQQLMEYRTEKEREKRLFDGRRDRSNGPAMELRLKQPSEVELEEYYPAFLDMVRNLFIGNLDPT-HYEDTLREMFTIHAYIVFTIDKLVQNITRQLHHLVSD--EICLKVVELYLSEKKRGAAG--GSLASQCVRAAKEASYQWKA-EHCMTDEN-CFKMMFLQRQGQVTMTIELLDTEDVQ 943
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Xenopus
Match: sin3b (SIN3 transcription regulator family member B [Source:NCBI gene;Acc:779742]) HSP 1 Score: 192.2 bits (487), Expect = 1.179e-49 Identity = 190/741 (25.64%), Postives = 325/741 (43.86%), Query Frame = 1
Query: 37 SNLSKIG-LEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDF--------IQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLG-YFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQ----------EDSDFDXXXXXXXXXXXXI-----------DRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGR--LLIQMIDPDNIK 2151
+++ K G L+ FNK+++ L + + CI LFN + EL + L ++P L+ F + + + D +N E ++ SC I G SYR LP + H KCSGR L C + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ MS E++ KF+LDD +GG+S ++ R+AIYRIYGD +++E LK P A+P+V+ R++ K +EW + F +W ++ + Y +SLD+Q ++ + D+ L+ + N+I S+Y+ Q R T GPHL + ED I+ D +LIT ++ + KED+ + + Q L FF + S + + ++ +L +R T E E V T +E Y+L N+ Y LRL H L RL LKI+ Q E FD N + E+ + Y L+++ + N D + ++ +R ++ A++ FTI +L+Q I + ++ + E +++LY K +G GS+A++ + K Y +A + C+ CF +F++++G+ + I+++D ++++
Sbjct: 224 ASVGKYGTLQEFSFFNKVRRVLKSQE------VYENFLRCIALFNQELVSGSELLQLVTPFLG-KFPELFAQFKSFLGVKELSFASPVTNDRSN-EGIGREIDYASCKRI-------------GSSYRALPKSFPHPKCSGRTAL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMSPEDQEKFRLDDRLGGTSEVIQRRAIYRIYGDKAPDIVESLKKNPVTAVPVVLKRLKAKEEEWREAQRGFNKIWREQYERAYLKSLDHQAVNFKQNDTKALRSKSLL----------------------------NEIESVYDERQEQQPDGR------------TTTSSGPHLIY---------------TYEDWQILEDAAALITFYVNRQPTIQKEDKDTIWQVLHQFLPELFFSSSSSSPSCQSLFAASADEGPTETVTESSVTELPERRRKTVTTEVAQEPPPPVETPHEPPPKTIDE-------VYSLFYTNNNWYFFLRLHHTLCSRL--LKIYRQAQQQLMEYRTEKEREKRLFDGRRDRSNGPAMELRLKQPSEVELEEYYPAFLDMVRNLFIGNLDPT-HYEDTLREMFTIHAYIVFTIDKLVQNITRQLHHLVSD--EICLKVVELYLSEKKRGAAG--GSLASQCVRAAKEASYQWKA-EHCMTDEN-CFKMMFLQRQGQVTMTIELLDTEDVQ 869
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Xenopus
Match: sin3b (SIN3 transcription regulator family member B [Source:NCBI gene;Acc:779742]) HSP 1 Score: 176.407 bits (446), Expect = 1.390e-44 Identity = 190/769 (24.71%), Postives = 324/769 (42.13%), Query Frame = 1
Query: 37 SNLSKIG-LEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDF--------IQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHD----------------------------CLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLG-YFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQ----------EDSDFDXXXXXXXXXXXXI-----------DRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGR--LLIQMIDPDNIK 2151
+++ K G L+ FNK+++ L + + CI LFN + EL + L ++P L+ F + + + D +N E ++ SC I G SYR LP + H KCSGR L D LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ MS E++ KF+LDD +GG+S ++ R+AIYRIYGD +++E LK P A+P+V+ R++ K +EW + F +W ++ + Y +SLD+Q ++ + D+ L+ + N+I S+Y+ Q R T GPHL + ED I+ D +LIT ++ + KED+ + + Q L FF + S + + ++ +L +R T E E V T +E Y+L N+ Y LRL H L RL LKI+ Q E FD N + E+ + Y L+++ + N D + ++ +R ++ A++ FTI +L+Q I + ++ + E +++LY K +G GS+A++ + K Y +A + C+ CF +F++++G+ + I+++D ++++
Sbjct: 263 ASVGKYGTLQEFSFFNKVRRVLKSQE------VYENFLRCIALFNQELVSGSELLQLVTPFLG-KFPELFAQFKSFLGVKELSFASPVTNDRSN-EGIGREIDYASCKRI-------------GSSYRALPKSFPHPKCSGRTALCKEEDLHHLLPGYRPRSYQTFYHEIHGKFYTKSVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMSPEDQEKFRLDDRLGGTSEVIQRRAIYRIYGDKAPDIVESLKKNPVTAVPVVLKRLKAKEEEWREAQRGFNKIWREQYERAYLKSLDHQAVNFKQNDTKALRSKSLL----------------------------NEIESVYDERQEQQPDGR------------TTTSSGPHLIY---------------TYEDWQILEDAAALITFYVNRQPTIQKEDKDTIWQVLHQFLPELFFSSSSSSPSCQSLFAASADEGPTETVTESSVTELPERRRKTVTTEVAQEPPPPVETPHEPPPKTIDE-------VYSLFYTNNNWYFFLRLHHTLCSRL--LKIYRQAQQQLMEYRTEKEREKRLFDGRRDRSNGPAMELRLKQPSEVELEEYYPAFLDMVRNLFIGNLDPT-HYEDTLREMFTIHAYIVFTIDKLVQNITRQLHHLVSD--EICLKVVELYLSEKKRGAAG--GSLASQCVRAAKEASYQWKA-EHCMTDEN-CFKMMFLQRQGQVTMTIELLDTEDVQ 938
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Mouse
Match: Sin3a (transcriptional regulator, SIN3A (yeast) [Source:MGI Symbol;Acc:MGI:107157]) HSP 1 Score: 176.407 bits (446), Expect = 1.290e-44 Identity = 186/726 (25.62%), Postives = 323/726 (44.49%), Query Frame = 1
Query: 37 SNLSKIGLEVVKLF-NKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTR-GSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
++ SK G+ LF +K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + S +R L L A Y +A ++ CF +FI+ +G +L ++++D
Sbjct: 454 ADASKHGVGTESLFFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLESFPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAPKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EVCVQVTDLYLAENNNGATGGQLNSQTSRSL-LESA--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTVELLD 1084
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Mouse
Match: Sin3a (transcriptional regulator, SIN3A (yeast) [Source:MGI Symbol;Acc:MGI:107157]) HSP 1 Score: 176.407 bits (446), Expect = 1.290e-44 Identity = 186/726 (25.62%), Postives = 323/726 (44.49%), Query Frame = 1
Query: 37 SNLSKIGLEVVKLF-NKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTR-GSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
++ SK G+ LF +K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + S +R L L A Y +A ++ CF +FI+ +G +L ++++D
Sbjct: 454 ADASKHGVGTESLFFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLESFPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAPKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EVCVQVTDLYLAENNNGATGGQLNSQTSRSL-LESA--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTVELLD 1084
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Mouse
Match: Sin3a (transcriptional regulator, SIN3A (yeast) [Source:MGI Symbol;Acc:MGI:107157]) HSP 1 Score: 176.407 bits (446), Expect = 1.290e-44 Identity = 186/726 (25.62%), Postives = 323/726 (44.49%), Query Frame = 1
Query: 37 SNLSKIGLEVVKLF-NKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTR-GSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
++ SK G+ LF +K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + S +R L L A Y +A ++ CF +FI+ +G +L ++++D
Sbjct: 454 ADASKHGVGTESLFFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLESFPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAPKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EVCVQVTDLYLAENNNGATGGQLNSQTSRSL-LESA--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTVELLD 1084
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Mouse
Match: Sin3a (transcriptional regulator, SIN3A (yeast) [Source:MGI Symbol;Acc:MGI:107157]) HSP 1 Score: 176.407 bits (446), Expect = 1.501e-44 Identity = 186/726 (25.62%), Postives = 323/726 (44.49%), Query Frame = 1
Query: 37 SNLSKIGLEVVKLF-NKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTR-GSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
++ SK G+ LF +K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + S +R L L A Y +A ++ CF +FI+ +G +L ++++D
Sbjct: 454 ADASKHGVGTESLFFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLESFPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAPKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EVCVQVTDLYLAENNNGATGGQLNSQTSRSL-LESA--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTVELLD 1084
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Mouse
Match: Sin3a (transcriptional regulator, SIN3A (yeast) [Source:MGI Symbol;Acc:MGI:107157]) HSP 1 Score: 176.407 bits (446), Expect = 1.501e-44 Identity = 186/726 (25.62%), Postives = 323/726 (44.49%), Query Frame = 1
Query: 37 SNLSKIGLEVVKLF-NKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTR-GSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
++ SK G+ LF +K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + S +R L L A Y +A ++ CF +FI+ +G +L ++++D
Sbjct: 454 ADASKHGVGTESLFFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLESFPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAPKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EVCVQVTDLYLAENNNGATGGQLNSQTSRSL-LESA--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTVELLD 1084
BLAST of Paired amphipathic helix protein Sin3a vs. UniProt/SwissProt
Match: sp|Q96ST3|SIN3A_HUMAN (Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2) HSP 1 Score: 176.407 bits (446), Expect = 8.935e-44 Identity = 185/735 (25.17%), Postives = 319/735 (43.40%), Query Frame = 1
Query: 4 DSEAYDLSKFNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
DS D SK + F+K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + + N L Y +A ++ CF +FI+ +G +L I+++D
Sbjct: 449 DSSMADASKHGGGTESL------FFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLETYPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EICVQVTDLYLAENNNGATGGQLNTQNSRSLLEST--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTIELLD 1083
BLAST of Paired amphipathic helix protein Sin3a vs. UniProt/SwissProt
Match: sp|Q60520|SIN3A_MOUSE (Paired amphipathic helix protein Sin3a OS=Mus musculus OX=10090 GN=Sin3a PE=1 SV=3) HSP 1 Score: 176.407 bits (446), Expect = 9.022e-44 Identity = 186/726 (25.62%), Postives = 323/726 (44.49%), Query Frame = 1
Query: 37 SNLSKIGLEVVKLF-NKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL-------------------SALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTR-GSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
++ SK G+ LF +K+++ L + + Y+ + C+ +FN I EL + L ++P L+ F + ++ V+ K+ EI+ R G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L + KK+ +S EE+ KF+LD+ +GG+S ++ RKA+ RIY D ++I+GL+ P +A+P+V+ R++ K +EW + F VW ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ T G VGPHL+L + ED I+ D +LI +H+ + + KED+ I Q++ +F P + ++ + D + + + + T ++ PK T + L+ YNL N+ Y +RL +L RL ++ IK + DS E + D Y L+++ + N D+S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY + +G + S +R L L A Y +A ++ CF +FI+ +G +L ++++D
Sbjct: 454 ADASKHGVGTESLFFDKVRKALRSAEA--YE----NFLRCLVIFNQEVISRAELVQLVSPFLG-KFPELFNWFKNFLG-YKESVHLESFPKERATEGIAMEIDYASCKRL-----GSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDER------------QEQATEENAGVPVGPHLSL---------------AYEDKQILEDAAALIIHHVKRQTGIQKEDKY----KIKQIMHHFI--PDLLFAQ----------RGDLSDVEEEEEEEMDVDEATGAPKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EVCVQVTDLYLAENNNGATGGQLNSQTSRSL-LESA--YQRKAEQLMSDEN--CFKLMFIQSQGQVQLTVELLD 1084
BLAST of Paired amphipathic helix protein Sin3a vs. UniProt/SwissProt
Match: sp|Q62141|SIN3B_MOUSE (Paired amphipathic helix protein Sin3b OS=Mus musculus OX=10090 GN=Sin3b PE=1 SV=2) HSP 1 Score: 162.54 bits (410), Expect = 1.796e-39 Identity = 103/326 (31.60%), Postives = 172/326 (52.76%), Query Frame = 1
Query: 37 SNLSKIG-LEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEK------KDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
+ + K G L+ F+K+++ L + + CI LFN + EL + L ++P L+ F + + +++ ++ SC I G SYR LP Y KCSGR IC + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ M+ E++ K +LDD +GG+S ++ R+AI+RIYGD +IE LK P A+P+V+ R++ K +EW + F +W ++ K Y +SLD+Q ++ + D+ L+ + ++I+S+
Sbjct: 288 AAVGKYGTLQEFSFFDKVRRVLKSQE------VYENFLRCIALFNQELVSGSELLQLVSPFLG-KFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRI-------------GSSYRALPKTYQQPKCSGRT--AICKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKLRLDDCLGGTSEVIQRRAIHRIYGDKAPEVIESLKRNPATAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESV 590
BLAST of Paired amphipathic helix protein Sin3a vs. UniProt/SwissProt
Match: sp|O75182|SIN3B_HUMAN (Paired amphipathic helix protein Sin3b OS=Homo sapiens OX=9606 GN=SIN3B PE=1 SV=2) HSP 1 Score: 150.984 bits (380), Expect = 9.113e-36 Identity = 105/356 (29.49%), Postives = 175/356 (49.16%), Query Frame = 1
Query: 37 SNLSKIG-LEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEK------KDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNL---------------------KICHDC---------LNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
+ + K G L+ F+K+++ L + + CI LFN + EL + L ++P L+ F + + +++ ++ SC I G SYR LP Y KCSGR + K + C LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ M+ E++ KF+LDD++GG+S ++ R+AIYRIYGD +IE LK P A+P+V+ R++ K +EW + F +W ++ K Y +SLD+Q ++ + D+ L+ + ++I+S+
Sbjct: 297 AAVGKYGTLQEFSFFDKVRRVLKSQE------VYENFLRCIALFNQELVSGSELLQLVSPFLG-KFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRI-------------GSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESV 631
BLAST of Paired amphipathic helix protein Sin3a vs. UniProt/SwissProt
Match: sp|Q09750|PST1_SCHPO (Paired amphipathic helix protein pst1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=pst1 PE=1 SV=1) HSP 1 Score: 117.857 bits (294), Expect = 2.181e-25 Identity = 69/183 (37.70%), Postives = 108/183 (59.02%), Query Frame = 1
Query: 379 GPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYG-DATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG 924
GPSYRLLP CSGR +L C LN+ ++ FP++ SED+ ++ +KN EE + KLE+ERYE D N ++ L KM MS+ EK + L N+GG S + K I ++YG + +IE L+ P + IP+V+ R+++K +EW + + + +W D K++++SLD+QG
Sbjct: 597 GPSYRLLPKIELLLPCSGRDDL--CWTILNDAWVSFPTLASEDSGFIAHRKNQFEENLHKLEEERYEYDRHIGANMRFIELLQIHADKMLKMSEVEKANWTLPSNLGGKSVSIYHKVIKKVYGKEHAQQIIENLQKNPSVTIPIVLERLKKKDREWRSLQNHWNELWHDIEEKNFYRSLDHQG 777
BLAST of Paired amphipathic helix protein Sin3a vs. TrEMBL
Match: A0A5K3EU93 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 214.157 bits (544), Expect = 1.695e-53 Identity = 128/338 (37.87%), Postives = 194/338 (57.40%), Query Frame = 1
Query: 346 RKDLRFS-FNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFF 1353
R DL F+ G SYR LPSD+ KCSGR I LN+ YI F S+ SED+ VSSKKN +EE + EDERYE DM E+N+ AL++L V +++E M ++E ++LDD +GG+SAILMRKAI+R+YGD ++I GLK P +P+VI RM +K EW + KF+ W D+ +K+Y +SLD+QG ++ +RD+ F++ T + I+++++G +S++ + D + + ++S S + P + LS G + G HLTL P + ++ D SLI +H+ SN SKED++ + + VL F
Sbjct: 12 RLDLDFNKLRTCGASYRALPSDFPQPKCSGRLKSSIARSVLNDTYISFSSLTSEDSQFVSSKKNQYEENMYHTEDERYEADMVMELNRAALQNLIVVRRRLERMGRDELQNYKLDDYLGGTSAILMRKAIHRVYGDKAGDVIYGLKTCPSSVVPIVIQRMHQKDTEWREAVRKFQQFWSDQDSKNYLRSLDHQGTNFKQRDNAFIRPKTVVNHIENIARGENSLSSEPASGDVVGSMIAKCLTSC--QSTTSSVCPATLGSALSHVFEGVGDDGGMHLTLEYPPPE---------TCASLLQDVASLIIHHVKRQSNTSKEDKRTMKFLVRAVLQDFL 338
BLAST of Paired amphipathic helix protein Sin3a vs. TrEMBL
Match: A0A0R3UHN6 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS6868 PE=4 SV=1) HSP 1 Score: 212.616 bits (540), Expect = 1.044e-52 Identity = 125/326 (38.34%), Postives = 190/326 (58.28%), Query Frame = 1
Query: 346 RKDLRFS-FNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLL 1317
R DL F+ G SYR LPSD+ KCSGR I LN+ YI F S+ SED+ VSSKKN +EE + EDERYE DM E+N+ AL++L V +++E M ++E ++LDD +GG+SAILMRKAI+R+YGD ++I GLK P +P+VI RM +K EW + KF+ W D+ +K+Y +SLD+QG ++ +RD+ F++ T + I+++++G +S++ + D + + ++S S + P + LS G + G HLTL P + ++ D SLI +H+ SN SKED++ +
Sbjct: 539 RLDLDFNKLRTCGASYRALPSDFPQPKCSGRLKSSIARSVLNDTYISFSSLTSEDSQFVSSKKNQYEENMYHTEDERYEADMVMELNRAALQNLIVVRRRLERMGRDELQNYKLDDYLGGTSAILMRKAIHRVYGDKAGDVIYGLKTCPSSVVPIVIQRMHQKDTEWREAVRKFQQFWSDQDSKNYLRSLDHQGTNFKQRDNAFIRPKTVVNHIENIARGENSLSSEPASGDVVGSMIAKCLTSC--QSTTSSVCPATLGSALSHVFEGVGDDGGMHLTLEYPPPE---------TCASLLQDVASLIIHHVKRQSNTSKEDKRTM 853
BLAST of Paired amphipathic helix protein Sin3a vs. TrEMBL
Match: A0A3R7FUM4 (Paired amphipathic helix protein Sin3a OS=Clonorchis sinensis OX=79923 GN=Sin3a PE=4 SV=1) HSP 1 Score: 212.231 bits (539), Expect = 1.708e-52 Identity = 153/490 (31.22%), Postives = 248/490 (50.61%), Query Frame = 1
Query: 19 DLSKFNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNS--------ENEKKDFHRISCNEIEIRKDLRFSFNDGGP------------------------------SYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSIN--QDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYG----NLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFF 1353
D+S + N G++V L +KI+ L N S+ Y + + LFN N++ + EL S++ L ++P ++ ++ + S E ++F +S N + D++ N G P SYR LPS++ KCSGR I + LN+ YI F S+ SED+ VSSKKN +EE + ++EDERYEVDM E+N+ A+++L V ++M+ M ++E +F LDDN+ G+SAILMRKAI+R+YGD ++I GLK RP A+PLVI RM++K EW ++ W ++ ++Y +SLD+QG + +RD+ ++ T SQI++++ S D + S L++ + ++ T G +G N++E NG PHL L+ P + + ++ D SLI +H+ SN SKED++ + + V+ F
Sbjct: 629 DVSVTDVNQLAGGVDV-SLLHKIRSVLCTDNGSDRAYQT--FLQALNLFNRNELSADELLQSVRPLFP-RHPDVWRRLCDTVSSASPTGHGSAVASERDREKHDREFRLLSSN-VPSAYDIQPDANPGPPLTGGGSAIPLLDVGHKRLDLDFMKLRTCGTSYRALPSNFPQSKCSGRLKCPIAREVLNDSYISFSSLTSEDSQFVSSKKNQYEEHMYRVEDERYEVDMVTELNRAAMQNLVVVKRRMDRMGQDELNRFTLDDNLSGTSAILMRKAIHRVYGDKAGDVIYGLKNRPSTAVPLVIQRMRQKDSEWRDAIRTYQRSWAEQDARNYLRSLDHQGATFKQRDAPLIRSKTMVSQIEAIAGDDKSCRTPPDLIGSMISASLTQRCL------TVRTDLKTPGTFGSALINVNEGYKENG---APHLALVYPPPATRNL---------LLEDAASLIIHHVKRQSNTSKEDKRTMKYLMRTVVQDLF 1095
BLAST of Paired amphipathic helix protein Sin3a vs. TrEMBL
Match: A0A068Y6F7 (Paired amphipathic helix protein sin3b OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000795100 PE=4 SV=1) HSP 1 Score: 210.305 bits (534), Expect = 5.522e-52 Identity = 182/603 (30.18%), Postives = 290/603 (48.09%), Query Frame = 1
Query: 346 RKDLRFS-FNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFP----------------------SGSVKEQKKSDRAAMTATDRKLKCKRTH------TNNEEQVYEKSSKVPK---RFSSKKFTFNE----------------------DLQSRHVK---YNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSD---------FDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLY 1953
R DL F+ G SYR LP ++ KCSGR I LN+ YI F S+ SED+ VSSKKN +EE + EDERYE DM E+N+ A+++L V ++++ MS++E F+LDD +GG+SAILM+KAI+R+YGD ++I GLK P +P+VI RM +K EW + KF+ W D+ K+Y +SLD+QG ++ +RD+ F + + I+ +++G +S + D + D + + ++ + SP + LS G G HLTL P + ++ D +SLI +H+ SN SKED++ + + VL FF +S+ S +V + S + M R+++ + H N ++V S+ P R SK+ T N D+ SR Y ++ GN+ Y LRL H+L+ RLS L+ S M QE + D + SE + Y+ L L+ D + D S ++++R+++ A+ WFT+ RLI + + ++ +G + S+ L L+
Sbjct: 569 RLDLDFNKLRTCGASYRALPPNFPQPKCSGRAKSAIARAVLNDTYISFSSLTSEDSQFVSSKKNQYEENMYHTEDERYEADMVMEVNRSAMQNLVVVRRRLDRMSRDEIQSFRLDDYLGGTSAILMKKAIHRVYGDKAGDVIYGLKTCPHTVVPIVIQRMVQKESEWKEALRKFQQYWADQDAKNYLRSLDHQGANFKQRDTAFTRPKAVVNLIEGIARGENSASSDPISGDVVGAMLAKCMACCPPGT--NSVSPATLGSALSHVIEGVGDNGGMHLTLEYPPPETCAL---------LLQDVSSLIIHHVKRQSNTSKEDKRTMKFLVRTVLQDFFMQERFPMSDDEGDDEDCENNEDYGVSENEASGDSETVMDTGDSTASGMPKRPRRMRHQTRHPRLHEPANGLKEVSPIPSEQPDLKMRRRSKRKTSNTGGNDSGDRENPLEFPKTPVTANDIPSRVPTEEYYCVLNGNNQWYAFLRLHHLLLTRLSQLRARSQLMQQEYAGEGGKSNNQVADVLRLRKKGQSEPKEYYSLALQLVKDLLDGCEDVH-SYEDRLRDMFGIYAYPWFTMDRLITNLVR-QLHVLASGDDLSQQLTSLF 1158
BLAST of Paired amphipathic helix protein Sin3a vs. TrEMBL
Match: A0A183SQ34 (HDAC_interact domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS6332 PE=4 SV=1) HSP 1 Score: 209.92 bits (533), Expect = 7.664e-52 Identity = 135/341 (39.59%), Postives = 198/341 (58.06%), Query Frame = 1
Query: 346 RKDLRFS-FNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIR-ILSRNKI--SSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFF 1353
R DL F+ G SYR LP+D+ KCSGR I LN+ YI F S+ SED+ VSSKKN +EE + EDERYE DM E+N+ AL++L V ++++ MS++E+ F LDD +GG+SAILM+KAI+R+YGD ++I GLK P +P+VI RM++K EW + F +W D+ K+Y +SLD+QG + +RD+ FL+ T +QI+++++G S + + D I +LS+ I SS Y+ S+H P + LS G + G H+TL P S ++ D SLI +H+ SN SKED++ + + VL F
Sbjct: 376 RLDLDFNKLRTCGASYRALPADFPQPKCSGRAKSAIARTVLNDSYISFSSLTSEDSQFVSSKKNQYEENMYHTEDERYEADMIMEVNRAALQNLIVVKRRIDRMSRDEQQNFHLDDLLGGTSAILMKKAIHRVYGDKAGDVIYGLKTCPATVVPIVIQRMRQKDNEWREAVRSFHRIWSDQDAKNYLRSLDHQGASFKQRDNPFLRTKTVINQIEAIARGEQSQSSESDSPDPIGCLLSKCLISCSSAYD-SLH----PGSLGSALSHVVEGIGDDGGMHMTLEYPPPS---------VCASLLEDVASLIIHHVKRQSNTSKEDKRAMKFLVRTVLQDLF 702
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Cavefish
Match: sin3b (SIN3 transcription regulator family member B [Source:ZFIN;Acc:ZDB-GENE-030131-8264]) HSP 1 Score: 184.882 bits (468), Expect = 1.931e-47 Identity = 189/730 (25.89%), Postives = 325/730 (44.52%), Query Frame = 1
Query: 73 LFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNS---------ENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYF----FGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKL--KCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRL--------SALKIHSIKMSQE-----------DSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGR--LLIQMIDPDNIK 2151
F+K+++ L KS + + CI LFN + EL + L ++P LY F + +K++ +S E ++ SC + G SYR LP Y KCSGR L C + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ +S E++ +F+LDD +GG+S ++ R+A+YRIYGD +IEGLK P A+PLV+ R++ K +EW + F +W ++ K Y +SLD+QG ++ + D L+ + N+I SIY+ Q++ G G G PHL T D + I+ D SLI H+ + K+D+ D+I +++ +F F + E+SE + +E + + T ++L + +R N+ + + P+ S++ ++L YNL N+ Y LRL L RL L H + S E +D + S E++ Y ++ S + S ++ +R ++ A++ FT+ +LIQ I + Q ++ + E + +LY K +G G+++++ + Y +A + CF +FI+ +G+ L I+++D + +
Sbjct: 362 FFDKVRR-LFKSQE-----VYENFLRCIALFNQEVVSGAELLQLVTPFLG-KFPELYTQFKSFLG--EKELTHSVSGLSDRYMEGGGREVDYASCKRL-------------GSSYRALPKTYQQPKCSGRTAL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRLSAEDQDRFRLDDCLGGTSEVIQRRAVYRIYGDKAPEIIEGLKKNPATAVPLVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQGVNFKQNDMKALRSKSLL----------------------------NEIESIYDER-QEQSTEEGGVGQQGRE--GAGVVTEPHLVF---TYED----------KQILEDAASLIIYHVKRQPTIHKDDK----DHIKRIIQHFVPDLFFSRRGELSETEDWTDEEVEGEEGGGSTGGQQQLNGEARRKRCNSVDGTRDPP---PQEERSEEQEQQKELDG---VYNLFFVNNNWYFFLRLHQTLCSRLLRVYRQAERQLLEHRAEQSAERLLVAEGRRDKATDLAMELRLKQPSEVELEEYYPAFLDMVRSLLDGNLESTQYEDTLREMFTIHAYIGFTVDKLIQNIVRQLQHLVSD--EVCLQVAELYTAERKRGAAG--GNLSSQCVRAAWETSYQWKAERVMAEEN--CFKVMFIQNKGQVTLTIELLDTEEAQ 1006
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Cavefish
Match: sin3aa (SIN3 transcription regulator family member Aa [Source:ZFIN;Acc:ZDB-GENE-070620-3]) HSP 1 Score: 178.718 bits (452), Expect = 2.071e-45 Identity = 183/664 (27.56%), Postives = 306/664 (46.08%), Query Frame = 1
Query: 37 SNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRIS---CNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQED---SDFDXX----------------XXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLY 1953
+ SK+G E + F K+++ L + + YD + C+ +FN I EL + L ++P L+ F + K++++ E+ K+ R + EI+ R F SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L V KK+ MS EE+ KF+LD+ +GG+S I+ RKAI RIYGD ++I+GLK P +++P+V+ R++ K +EW + F +W ++ K+Y +SLD+QG ++ + D+ L+ T N+I SIY+ + G TP + GPHLT + ED I+ D +LI +H+ +++ KED+ I Q++ +F P + S+ G++ + ++ + + H E S K S + + L++ YNL N+ Y LRL H L RL L + + +ED D++ E + D Y+ L ++ + + N +AS ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY
Sbjct: 482 AEASKVGTESL-FFEKVRKALRSAEA--YD----NFLRCLVVFNQEVISRAELVQLVLPFLG-KFPELFTWFKNFLG--YKEISHLESYPKE--RATEGIAMEIDYSSCKRLGF-----SYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLETVQKKLSRMSAEEQAKFRLDNTLGGTSEIIHRKAIQRIYGDKAMDIIDGLKKNPAVSVPIVLKRLKLKEEEWREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKVLRSKTLL----------------------------NEIESIYDERQEQASEENG-------TPPS-----GPHLTF---------------TYEDRHILEDAAALIIHHVKRQTSIQKEDKY----KIKQIIYHFI--PDMLFSQ--RGALSDAEEEEDEEDMEL--DEGGSKKHNGLAEAGSAGSPPKSKLLFSN--SAAQKLRTCDEAYNLFFVNNNWYIFLRLHHTLCSRLLRLYAQAERQIEEDIRERDWEREVLGLKRDKNDNPAIQLRLKEPMDIDVEDYYSAFLEMVRNLLDGNMEAS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EICVQVTDLY 1055
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Cavefish
Match: sin3ab (SIN3 transcription regulator family member Ab [Source:ZFIN;Acc:ZDB-GENE-030131-2066]) HSP 1 Score: 125.561 bits (314), Expect = 8.034e-29 Identity = 94/269 (34.94%), Postives = 147/269 (54.65%), Query Frame = 1
Query: 13 AYDLSKFNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISR 819
A + SKF IG E + F K+++ L + + YD + C+ +FN I EL + L ++P L+ F + + S +++ I+ EI+ R F SYR LP + KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L V K++ MS EE+ KF+LD+ +GGSS ++ RKAI RIYG+ ++I+GLK P +++P+V+ R
Sbjct: 439 AAEGSKFG-----IGTESL-FFEKVRKVLRSAEA--YD----NFLRCLVIFNQEVISKAELVQLVLPFLG-KFPELFTWFKNFLGYKECAHIESFPKERATEGIAM-EIDYSSCKRLGF-----SYRALPKSFQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLETVQKRLSRMSAEEQAKFRLDNTMGGSSEVIHRKAIQRIYGEKAADIIDGLKRNPAVSVPIVLKR 685
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Sea Lamprey
Match: sin3ab (SIN3 transcription regulator family member Ab [Source:ZFIN;Acc:ZDB-GENE-030131-2066]) HSP 1 Score: 200.29 bits (508), Expect = 6.694e-53 Identity = 199/739 (26.93%), Postives = 338/739 (45.74%), Query Frame = 1
Query: 4 DSEAYDLSKFNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLG-YFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKK------FTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIH----------------SIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGR--LLIQMIDPD 2142
D+ + D SK S L F+K+++ L KS+ + + C+ LFN + EL + L ++P L+ F + K+ ++ E KD S I + D S GPSYR LP Y KCSGR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D E N ++ L V+KK+ MS+E+K +F LD +GG+S ++ RKA+ RIYGD + +I+GLK P +A+P+V+ R++ K +EW + F +W ++ K+Y +SLD+QG ++ + D+ L+ + N+I +IY+ ++ + GN+S GPHL + + I+ D SLI +H+ + + ED+ + I ++ FFG+ G E+S+ + ++ + A + + K + KS + K T L+ YNLM N+ Y LRL +L RL L+I+ + K +++S + S E D Y L+++ + + N ++S ++ +R ++ A++ FT+ +LIQ I + Q I+ + E +++LY S P+ T GS+A + Y + ++ CF +FI+ EGR L+++++D D
Sbjct: 444 DTSSADSSKHGS------LGEFAFFDKVRKAL-KSHE-----VYENFLRCLVLFNQEVVSRSELVQLVFPFLG-KFPELFSWFKTFVG--YKEFSHPEALPKDR---SAEGIAMEIDYA-SCKRLGPSYRALPKSYQQPKCSGRTPL--CREVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDYVLETNLATIRVLESVHKKLSRMSEEDKARFHLDSCLGGTSEVVHRKAVQRIYGDKANEIIDGLKKNPAVAVPVVLKRLKAKDEEWREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKALRSKSLL----------------------------NEIETIYD-----EHQEQAAEGNVSPA-------SGPHL-------------DYEYEDKQILEDAASLIIHHVKRQTGIQTEDKHKIKQLIYHLVPDLFFGSRG-ELSDMEESAAGDEDAAPTVASSTDSAEGKANGPADGSSPGKGNKSEGSGGGSVTGKSKLLFATTHAHKLKGLEHVYNLMFVNNNWYIFLRLHQLLCSRL--LRIYMQAERQMEEERMGSEPAAKKDKKESPAYQLRLKQPSELEVDDYYPAFLDMVKNLLDGNMESS-HYEDTLREMFTIHAYIGFTMDKLIQNIVRQLQHIVTD--EVCVRVMELYLGES---PAATGGSLATQSSRSSHEAAYQKKVEQHMSDEN--CFKVMFIQSEGRVKLMVELLDTD 1096
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Yeast
Match: SIN3 (Component of both the Rpd3S and Rpd3L histone deacetylase complexes; involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity [Source:SGD;Acc:S000005364]) HSP 1 Score: 111.694 bits (278), Expect = 2.538e-25 Identity = 78/278 (28.06%), Postives = 144/278 (51.80%), Query Frame = 1
Query: 235 HLYYDFIQIMNKIQKDVNNSEN--EKKDFH-------------------RISCNEIEIRKDLRFSFN---DGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATD-NMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
HLY +F++I+N +D+ + ++ EK DF+ + C E + + R + GPSY+ LP CSGR ++ C + LN+E++ P SED+ ++ +KN +EE + K+E+ER+E D + E N ++ L + K+E+M++ EK F+L +G +S + +K I ++Y +I+ L P + P+V+ R+++K +EW + ++ VW + K +++SLD+ G + + D L S+I S+
Sbjct: 680 HLYTEFLKILNLYSQDILDLDDLVEKVDFYLGSNKELFTWFKNFVGYQEKTKCIENIVHEKHRLDLDLCEAFGPSYKRLPKSDTFMPCSGRDDM--CWEVLNDEWVGHPVWASEDSGFIAHRKNQYEETLFKIEEERHEYDFYIESNLRTIQCLETIVNKIENMTENEKANFKLPPGLGHTSMTIYKKVIRKVYDKERGFEIIDALHEHPAVTAPVVLKRLKQKDEEWRRAQREWNKVWRELEQKVFFKSLDHLGLTFKQADKKLLTTKQLISEISSI 955
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Nematostella
Match: EDO41458 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4D8]) HSP 1 Score: 151.369 bits (381), Expect = 2.953e-37 Identity = 136/479 (28.39%), Postives = 216/479 (45.09%), Query Frame = 1
Query: 73 LFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTP---------------GIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKR 1464
F+K+++ L + YD + C+ LFN I EL + L ++P L F + + KD + E+ R S + D S G SYR LP Y KCSGR ++ C + LN+ ++ FPS SEDT ++K +EE I + EDER+E+D+ E N ++ L V KK++ MS EE+ KF+LD +GG+S I+ +KAI RIYGD ++I+G+K P +A+PLV+ R Q K +EW + +F +W D+ K+Y +SLD+QG K++ + RS N+I SI++ + + G N GPH+ S I++D LI +H+ +++ KED+ + + + F P GI E P+G + + A++ D+ +C R
Sbjct: 365 FFDKVRKAL--KSPEVYD----NFLRCLVLFNQEVISRSELVQLASNFLG-KFPDLLTWFKEFLG--YKDSSPMESMSGFKERTSGELAHLEIDYA-SCKRYGTSYRALPKSYTQPKCSGRSDM--CKEVLNDTWVSFPSW-SEDTPFPGTRKTQYEEYIFRCEDERFELDVVLESNLSTIRVLEAVQKKLQRMSSEEQQKFRLDSCLGGTSEIVHKKAIQRIYGDKAPDIIDGIKKTPAVAVPLVLKR-QAKEEEWRESQRQFNKIWRDQNEKYYLKSLDHQGITFKQNDLKAMRSKSL---------------------------MNEIESIFDE--RQEQAAEG-----------NADAGGPHIVFTYQDKS-------------ILDDAAGLIVHHMKRQTSIHKEDKAKIKLLLHCFVPDLFFAPRGELSDDEDSVKEMNGISKPEMPNGVAEAE------AVSVLDQAKRCHR 770
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Medaka
Match: sin3aa (SIN3 transcription regulator family member A [Source:NCBI gene;Acc:101171907]) HSP 1 Score: 175.252 bits (443), Expect = 2.636e-44 Identity = 192/735 (26.12%), Postives = 327/735 (44.49%), Query Frame = 1
Query: 4 DSEAYDLSKFNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSAL-------------------KIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
D A D SK + F K+++ L + + YD + C+ +FN I EL + L ++P L+ F + +++++ E K+ + I + D S G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L V K+ MS EE+ KF+LD+ +GGSS ++ RKAI RIYGD ++I+GLK P +++P+V+ R++ K +EW + F +W ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ +E T T GPHLTL + ED I+ D +LI +H+ +++ KED+ I Q++ +F P + S+ G + + ++ + + K+ +N SK FS+ T + L+ YNL N+ Y +RL L RL L ++ +K + D+ E E D Y+ L ++ + + N +AS ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY S +G G+++ Y +A ++ CF +F + G +L ++++D
Sbjct: 453 DPSAADPSKHGGGTESL------FFEKVRKALRSAEA--YD----NFLRCLVIFNQEVISRAELVQLVLPFLG-KFPELFNWFKNFLG--YREMSHIETYPKER---ATEGIAMEIDYA-SCKRLGSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLETVQWKLSRMSAEEQAKFRLDNTLGGSSEVIHRKAIQRIYGDKAADIIDGLKKNPAVSVPIVLKRLKTKEEEWREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDERQE----------QATEENATAPT--GPHLTL---------------TYEDSQILEDAAALIIHHVKRQTSIQKEDKY----KIKQIIYHFL--PDMLFSQ--RGELSDLEEEEEEEEEMDLEEGAGKK---HNGVAAGGSPSKSKLLFSN---TAAQKLRGCDDAYNLFFVNNNWYIFMRLHQTLCSRLLRLYGQAERQIEEEVRERDWEREVLGLKKEKNDNPAIQLRLKEPMDIEVEDYYSAFLEMVKNLLDGNMEAS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EICVQVTDLYLAESANGAAG--GALSTLSARSTAEGVYQRKAEQLMSDEN--CFKVMFSKSRGTVQLTVELLD 1089
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Medaka
Match: sin3aa (SIN3 transcription regulator family member A [Source:NCBI gene;Acc:101171907]) HSP 1 Score: 172.17 bits (435), Expect = 1.814e-43 Identity = 182/689 (26.42%), Postives = 310/689 (44.99%), Query Frame = 1
Query: 142 LFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIED--IINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSAL-------------------KIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEG--RLLIQMID 2136
C+ +FN I EL + L ++P L+ F + +++++ E K+ + I + D S G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L V K+ MS EE+ KF+LD+ +GGSS ++ RKAI RIYGD ++I+GLK P +++P+V+ R++ K +EW + F +W ++ K+Y +SLD+QG ++ + D+ L+ + N+I SIY+ +E T T GPHLTL + ED I+ D +LI +H+ +++ KED+ I Q++ +F P + S+ G + + ++ + + K+ +N SK FS+ T + L+ YNL N+ Y +RL L RL L ++ +K + D+ E E D Y+ L ++ + + N +AS ++ +R ++ A++ FT+ +LIQ I + Q I+ + E + DLY S +G G+++ Y +A ++ CF +F + G +L ++++D
Sbjct: 312 FLRCLVIFNQEVISRAELVQLVLPFLG-KFPELFNWFKNFLG--YREMSHIETYPKER---ATEGIAMEIDYA-SCKRLGSSYRALPKSYQQPKCTGRTPL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRVLETVQWKLSRMSAEEQAKFRLDNTLGGSSEVIHRKAIQRIYGDKAADIIDGLKKNPAVSVPIVLKRLKTKEEEWREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL----------------------------NEIESIYDERQE----------QATEENATAPT--GPHLTL---------------TYEDSQILEDAAALIIHHVKRQTSIQKEDKY----KIKQIIYHFL--PDMLFSQ--RGELSDLEEEEEEEEEMDLEEGAGKK---HNGVAAGGSPSKSKLLFSN---TAAQKLRGCDDAYNLFFVNNNWYIFMRLHQTLCSRLLRLYGQAERQIEEEVRERDWEREVLGLKKEKNDNPAIQLRLKEPMDIEVEDYYSAFLEMVKNLLDGNMEAS-QYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSD--EICVQVTDLYLAESANGAAG--GALSTLSARSTAEGVYQRKAEQLMSDEN--CFKVMFSKSRGTVQLTVELLD 914
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Medaka
Match: sin3b (SIN3 transcription regulator family member B [Source:NCBI gene;Acc:101165470]) HSP 1 Score: 169.474 bits (428), Expect = 1.532e-42 Identity = 104/307 (33.88%), Postives = 168/307 (54.72%), Query Frame = 1
Query: 73 LFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
F+K+++ L KS + + CI LFN + EL + L ++P LY F + + S + E++ R G SYR LP Y KCSGR L C + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ +S E++ +F+LDD +GG+S ++ R+++YRIYGD +IEGLK P A+P+V+ R++ K +EW + F +W ++ K Y +SLD+QG ++ + D L+ + ++I+S+
Sbjct: 363 FFDKVRR-LFKSQE-----VYENFLRCIALFNQEVVSGAELLQLVTPFLG-KFPELYSQFKSFLGDKELCHGVSGLSDRYMEGGGGREVDYASCKRL-----GSSYRALPKTYQQPKCSGRTAL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLARLSPEDQDRFRLDDCLGGTSEVIQRRSVYRIYGDKAPEIIEGLKRSPATAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQGVNFKQNDMKALRSKSLLNEIESI 654
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Medaka
Match: sin3b (SIN3 transcription regulator family member B [Source:NCBI gene;Acc:101165470]) HSP 1 Score: 168.318 bits (425), Expect = 2.778e-42 Identity = 104/307 (33.88%), Postives = 168/307 (54.72%), Query Frame = 1
Query: 73 LFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
F+K+++ L KS + + CI LFN + EL + L ++P LY F + + S + E++ R G SYR LP Y KCSGR L C + LN+ ++ FPS SED++ VSSKK +EEQ+ + EDER+E+D+ E N ++ L V KK+ +S E++ +F+LDD +GG+S ++ R+++YRIYGD +IEGLK P A+P+V+ R++ K +EW + F +W ++ K Y +SLD+QG ++ + D L+ + ++I+S+
Sbjct: 276 FFDKVRR-LFKSQE-----VYENFLRCIALFNQEVVSGAELLQLVTPFLG-KFPELYSQFKSFLGDKELCHGVSGLSDRYMEGGGGREVDYASCKRL-----GSSYRALPKTYQQPKCSGRTAL--CKEVLNDTWVSFPSW-SEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLARLSPEDQDRFRLDDCLGGTSEVIQRRSVYRIYGDKAPEIIEGLKRSPATAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQGVNFKQNDMKALRSKSLLNEIESI 567
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Medaka
Match: ENSORLT00000001808.2 (paired amphipathic helix protein Sin3a [Source:NCBI gene;Acc:101163723]) HSP 1 Score: 164.466 bits (415), Expect = 6.066e-41 Identity = 104/307 (33.88%), Postives = 172/307 (56.03%), Query Frame = 1
Query: 73 LFNKIKQHLHKSNSSNYDYISTHLFNCIKLFNDNKIDSFELKNSIKSLLDCQYPHLYYDFIQIMNKIQKDVNNSENEKKDFHRISCNEIEIRKDLRFSFNDGGPSYRLLPSDYNHKKCSGRKNLKICHDCLNNEYICFPSMISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQG-DWTKRDSIFLKRSTFFSQIDSL 990
F K+K+ L ++ Y+ + C+ +FN I EL + L ++P L+ F + + + + + S I + D S G SYR LP Y KC+GR L C + LN+ ++ FPS SED++ VSSKK +EE I + EDER+E+D+ E N ++ L V +K+ MS EE+++F+LD+ +GGSS ++ RKAI RIYGD ++I+GLK P +++P+V+ R++ K +EW + F +W ++ K+Y +SLD+QG ++ + D+ L+ T ++I+ L
Sbjct: 454 FFEKVKKALR--SAEGYE----NFLRCLYIFNQEVISRTELVQLVIPFLG-KFPELFTWFKNFLGYRESSYGETSHAESLPKERSTEGIAMEIDYA-SCKRLGSSYRALPKSYQQPKCTGRTPL--CREVLNDTWVSFPSW-SEDSTFVSSKKTQYEEHIYRCEDERFELDIVLETNLATIRVLETVQRKISRMSAEEQLRFRLDNTLGGSSEVIHRKAIQRIYGDKAHDIIDGLKRNPAVSVPIVLKRLKMKDEEWREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKMLRSKTLLNEIEML 749
BLAST of Paired amphipathic helix protein Sin3a vs. Planmine SMEST
Match: SMESG000036802.1 (SMESG000036802.1) HSP 1 Score: 1429.85 bits (3700), Expect = 0.000e+0 Identity = 729/731 (99.73%), Postives = 731/731 (100.00%), Query Frame = 1
Query: 493 MISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQIXXXXXXXXXXPMFLRKNLRKCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISR 2685
MISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNKKMESMSKEEKMKFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLR+CVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVIS+
Sbjct: 1 MISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNKKMESMSKEEKMKFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLRRCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISQ 731
BLAST of Paired amphipathic helix protein Sin3a vs. Planmine SMEST
Match: SMESG000036802.1 (SMESG000036802.1) HSP 1 Score: 1426.38 bits (3691), Expect = 0.000e+0 Identity = 732/733 (99.86%), Postives = 733/733 (100.00%), Query Frame = 1
Query: 493 MISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNXXXXXXXXXXXXXFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQIXXXXXXXXXXPMFLRKNLRKCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISRIQ 2691
MISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNKKMESMSKEEKMKFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLR+CVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISRIQ
Sbjct: 1 MISEDTSAVSSKKNIHEEQITKLEDERYEVDMFQEINKYALKHLCEVNKKMESMSKEEKMKFQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLRRCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISRIQ 733
BLAST of Paired amphipathic helix protein Sin3a vs. Planmine SMEST
Match: SMESG000036802.1 (SMESG000036802.1) HSP 1 Score: 1335.47 bits (3455), Expect = 0.000e+0 Identity = 668/670 (99.70%), Postives = 670/670 (100.00%), Query Frame = 1
Query: 676 FQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQIXXXXXXXXXXPMFLRKNLRKCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISR 2685
FQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLR+CVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVIS+
Sbjct: 12 FQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLRRCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISQ 681
BLAST of Paired amphipathic helix protein Sin3a vs. Planmine SMEST
Match: SMESG000036802.1 (SMESG000036802.1) HSP 1 Score: 1332.01 bits (3446), Expect = 0.000e+0 Identity = 671/672 (99.85%), Postives = 672/672 (100.00%), Query Frame = 1
Query: 676 FQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQIXXXXXXXXXXPMFLRKNLRKCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISRIQ 2691
FQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLR+CVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISRIQ
Sbjct: 12 FQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLRRCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISRIQ 683
BLAST of Paired amphipathic helix protein Sin3a vs. Planmine SMEST
Match: SMESG000036802.1 (SMESG000036802.1) HSP 1 Score: 1332.01 bits (3446), Expect = 0.000e+0 Identity = 671/672 (99.85%), Postives = 672/672 (100.00%), Query Frame = 1
Query: 676 FQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDXXXXXXXXXXXXIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQIXXXXXXXXXXPMFLRKNLRKCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISRIQ 2691
FQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLR+CVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISRIQ
Sbjct: 9 FQLDDNIGGSSAILMRKAIYRIYGDATDNMIEGLKVRPKMAIPLVISRMQEKTKEWNQIHSKFKMVWEDRANKHYWQSLDYQGDWTKRDSIFLKRSTFFSQIDSLSKGFSSINQDFLKSDFIRILSRNKISSIYEHSIHTQNSPRGIYGNLSETPLTNGTEVGPHLTLLLPTDSDLFIANVGISIEDIINDTNSLITNHITMLSNLSKEDRQLLIDYISQVLGYFFGTPGIEISEFPSGSVKEQKKSDRAAMTATDRKLKCKRTHTNNEEQVYEKSSKVPKRFSSKKFTFNEDLQSRHVKYNLMIGNSYMYTLLRLVHVLIDRLSALKIHSIKMSQEDSDFDNSCYNENSSSEEIDRYNKVLNLLIDSNELNSDASLSIDNKIRNLYHTKAFLWFTIPRLIQQIAKTSQQIICNGLESSKDLLDLYCIHSKFQPSGTRGSMANRELYLPKAIKYTNEAVDFCINQGMICFLFVFIRQEGRLLIQMIDPDNIKRATVFSNGGSECESTISDNLKPITDDTTDCLSCYGKPPTEIAPSAQISNSNKNRNNNPMFLRKNLRRCVRQLNERLIDYWRNKSLDQSFPSMEEIILMKSSDDEAAGNNEGLIDYLRDPIKEYYRNAFDGAGEVFEFLFDRSEKSNKNGYLIKKSIFCRNLNSERISRRISLEEVISRIQ 680 The following BLAST results are available for this feature:
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 4
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Paired amphipathic helix protein Sin3a vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Paired amphipathic helix protein Sin3a vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Paired amphipathic helix protein Sin3a vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Paired amphipathic helix protein Sin3a vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033761 ID=SMED30033761|Name=Paired amphipathic helix protein Sin3a|organism=Schmidtea mediterranea sexual|type=transcript|length=2798bpback to top protein sequence of SMED30033761-orf-1 >SMED30033761-orf-1 ID=SMED30033761-orf-1|Name=SMED30033761-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=898bp MDSEAYDLSKFNSNLSKIGLEVVKLFNKIKQHLHKSNSSNYDYISTHLFNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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