Ess-2 splicing factor homolog

Overview
NameEss-2 splicing factor homolog
Smed IDSMED30033747
Length (bp)1340
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ess-2 splicing factor homolog (SMED30033747) t-SNE clustered cells

Violin plots show distribution of expression levels for Ess-2 splicing factor homolog (SMED30033747) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ess-2 splicing factor homolog (SMED30033747) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ess-2 splicing factor homolog (SMED30033747) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30033747

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
neoblastSMED30033747SMESG000033822.1 dd_Smed_v4_5877_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Human
Match: ESS2 (ess-2 splicing factor homolog [Source:HGNC Symbol;Acc:HGNC:16817])

HSP 1 Score: 152.91 bits (385), Expect = 9.378e-41
Identity = 135/450 (30.00%), Postives = 217/450 (48.22%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKDERDLH---------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQSKT----KVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXX--XXXXXXWGEIDGTP--VEIPDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNR--PTSSRSIMSPAAIKLLSRMTPS-TPKSF-ISTRPNSVYSLNVKSTPSTRRYGSSTPG-----------NPASITDNLLDI 1306
            V+DE+++I+ LQ +I RDFFPD E L+ Q +Y +A +  D   M++I +K             +     S     PY  P+  +  ++H                                 LD +LS++TSEDN S+ ++ +   ER   + +W ++A +E++  + ++LE     P+      +  +++ +  +YK  N + + P  V    EE+LF    KP +++++NTRF + P +   +R +  Q+         GK+G DGKEL    +PRV GF  +           +P  TWGE++ TP  VE  ++P V R     F+I EP  RE+L  +MA++ A KN+ KKQ+AL RV  NL    P      MSPA  +L+SR     T ++   S  P+   S ++K+  S  +  +STP            +PASITDNLL +
Sbjct:   37 VLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFG-----------SALGKMSREPPPPYVTPATFETPEVHAGTGVVGNKPRPRGRGLEDGEAGEEEEKEPLPSLDVFLSRYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEKRQKDNLEL----PSAEHQAIESSQASVETWKYKAKNSLMYYPEGV--PDEEQLF---KKPRQVVHKNTRFLRDPFSQALSRCQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPMMTWGEVENTPLRVEGSETPYVDRTPGPAFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSTHLKTPASGLQTPTSTPAPGSATRTPLTQDPASITDNLLQL 466
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Human
Match: ESS2 (ess-2 splicing factor homolog [Source:HGNC Symbol;Acc:HGNC:16817])

HSP 1 Score: 72.7886 bits (177), Expect = 1.295e-13
Identity = 63/252 (25.00%), Postives = 116/252 (46.03%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKDERDLH---------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQS 796
            V+DE+++I+ LQ +I RDFFPD E L+ Q +Y +A +  D   M++I +K             +     S     PY  P+  +  ++H                                 LD +LS++TSEDN S+ ++ +   ER   + +W ++A +E++       +   ELP+      +  +++ +  +YK  N + + P  V    EE+LF    KP +++++NTRF + P +   +R +  Q+
Sbjct:   37 VLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFG-----------SALGKMSREPPPPYVTPATFETPEVHAGTGVVGNKPRPRGRGLEDGEAGEEEEKEPLPSLDVFLSRYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEK----RQKDNLELPSAEHQAIESSQASVETWKYKAKNSLMYYPEGV--PDEEQLF---KKPRQVVHKNTRFLRDPFSQALSRCQLQQA 268
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Celegans
Match: ess-2 (Splicing factor ESS-2 [Source:UniProtKB/Swiss-Prot;Acc:P34420])

HSP 1 Score: 94.7449 bits (234), Expect = 9.990e-21
Identity = 120/466 (25.75%), Postives = 182/466 (39.06%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAP--------YKNPSAKDERDLH------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQ-----YKIFNPVFFNPGSVELSAEERLFLA-GSKPEIMYENTRFK-----TPLNIVRNRPKTNQSKTKVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEIPDSPIVSR---------FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPT-SSRSI------MSPAAIKLLS-----RMTPSTPKSFI----------------STRPNSVYSLNVKSTPSTRRYGSSTPGNPA 1279
            VV E+K+I  L  II +D+FP  + ++ Q +Y +A+  +D   +KE+Q+K      V  +       +   +T AP           PS+      H                              L  YL+K+TSEDN S+ +L K   ER+  +  W +KA +E++   +       E       K+     +N+ L      YK +N V FNP    L+  E    A   + EI    TRF       P +    R   + +     GK+   G E+    TP    F +L   +           TWGEIDGTP  + D+P V+          F+I E   REK+A  M   +A K +DK++ A+         P   S+ +      +SPAA KL +     +M P+    F                 ST P S +S    +  S+   G+ TPG P 
Sbjct:   41 VVPEEKYIAGLDKIIEKDYFPHLKKMQAQKEYLEAVANKDINKIKELQMKFCSTGSVRTDRSFRTPITTRSTTEAPDVSSFDADTPGPSSASTSSAHDWMQSPMPFANEEGDNEALNRKRKKKKEETLTSYLNKYTSEDNASFEELAKVMREREDARRPWVYKAEEEHNKNLVTRQAIAAEADVQLALKHAVDADDNRPLNVDNWAYKAWNTVLFNPDGAALTPAEIADAARKQQTEINKRGTRFPDSGKLKPSDEAMTRAAVSHALANA-GKVDFLGNEV----TP-ANSFKLLETPNPNPDDMDSPLMTWGEIDGTPFRL-DAPDVTEHSLPGAAPVFKIPEVPYREKIAQSMNDSIAAKYRDKRKVAMRAAEGAHRTPGFGSKRVSDKLAQLSPAAQKLATKKLGLKMLPAHKSPFASPKIMSNWSRPSSSKRSTTPGSAWSRGSTTPGSSWSQGAQTPGTPG 499
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Celegans
Match: ess-2 (Splicing factor ESS-2 [Source:UniProtKB/Swiss-Prot;Acc:P34420])

HSP 1 Score: 93.2041 bits (230), Expect = 3.503e-20
Identity = 119/468 (25.43%), Postives = 181/468 (38.68%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAP--------YKNPSAKDERDLH------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKIL-----QYKIFNPVFFNPGSVELSAEERLFLA-GSKPEIMYENTRFK-----TPLNIVRNRPKTNQSKTKVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEIPDSPIVSR---------FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRS---------NLNRPTSSRSIMSPAAIKLLS-----RMTPSTPKSFI----------------STRPNSVYSLNVKSTPSTRRYGSSTPGNPA 1279
            VV E+K+I  L  II +D+FP  + ++ Q +Y +A+  +D   +KE+Q+K      V  +       +   +T AP           PS+      H                              L  YL+K+TSEDN S+ +L K   ER+  +  W +KA +E++   +       E       K+     +N+ L      YK +N V FNP    L+  E    A   + EI    TRF       P +    R   + +     GK+   G E+    TP    F +L   +           TWGEIDGTP  + D+P V+          F+I E   REK+A  M   +A K +DK++ A+                 R +   + +SPAA KL +     +M P+    F                 ST P S +S    +  S+   G+ TPG P 
Sbjct:   41 VVPEEKYIAGLDKIIEKDYFPHLKKMQAQKEYLEAVANKDINKIKELQMKFCSTGSVRTDRSFRTPITTRSTTEAPDVSSFDADTPGPSSASTSSAHDWMQSPMPFANEEGDNEALNRKRKKKKEETLTSYLNKYTSEDNASFEELAKVMREREDARRPWVYKAEEEHNKNLVTRQAIAAEADVQLALKHAVDADDNRPLNVDNWAYKAWNTVLFNPDGAALTPAEIADAARKQQTEINKRGTRFPDSGKLKPSDEAMTRAAVSHALANA-GKVDFLGNEV----TP-ANSFKLLETPNPNPDDMDSPLMTWGEIDGTPFRL-DAPDVTEHSLPGAAPVFKIPEVPYREKIAQSMNDSIAAKYRDKRKVAMRAAEGAHFSRTPGFGSKRVSDKLAQLSPAAQKLATKKLGLKMLPAHKSPFASPKIMSNWSRPSSSKRSTTPGSAWSRGSTTPGSSWSQGAQTPGTPG 501
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Fly
Match: Es2 (gene:FBgn0023506 transcript:FBtr0071198)

HSP 1 Score: 108.997 bits (271), Expect = 1.950e-25
Identity = 129/415 (31.08%), Postives = 183/415 (44.10%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLK--LNRI----------NEVFENXXXXXXXXXXXXXXAPYKNPSAKDE--------------RD----LHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAI-TDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKPEIMYENTRFKTPLNIVRNRPKTNQSKTKVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEI--PDSPI----VSRFRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSI-----MSPAAI-----KLLSRMTP---STPKSFISTRPNSVYSLNVKST 1234
            ++ E+K+I+++  II RDFFPD E L  Q  Y DA   +DF  M EI+ +  L RI          N     +      S++  ++ P  N  A D               RD    L LD +L K+TSEDN S+ ++    IE    KL   +     ++ L  E L+    LP+I T  +        +   Y   N + + P  VE + EER+ LA  K  I +  TR   P         T +   +VP + G  G    +  TP+V GF +L               TWGEIDGTP  +   D+P+       FRI E S RE +A  +A +V+ + +++KQ ALD  R N+  P    ++     MSPAA      KL  R TP    TP S +S R   V    V+ST
Sbjct:   50 ILTEEKYIEEMSKIIQRDFFPDLERLRAQNDYLDAESRRDFVQMAEIRERYSLGRISGTGRSTSRRNNAMSPATFETPVSQAKCSNTPLPNSRATDTPFSTDGSEKSDAEGRDTTAKLSLDAFLQKYTSEDNQSFQEI----IETAEAKLRQKYAVLYNHEKLSAEQLQRALMLPSIETQFEEPDPLRKIETWNYTNMNSIMYVPDGVEYTEEERVQLAERKQSIQHNATRL--PDEAKHREMDTKKLNDEVP-QNGAGG----ATATPKVRGFDLLRSPSPRPGEAFSPIMTWGEIDGTPFRLDGGDTPLRPTQGPSFRINENSRRENIAIALAERVSERMRNQKQMALDTARRNIGSPLIRTNMERLASMSPAAQLLATGKLGIRGTPRLRHTP-SPMSGRKRKVTPGVVRST 452
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Zebrafish
Match: ess2 (ess-2 splicing factor homolog [Source:ZFIN;Acc:ZDB-GENE-030131-2843])

HSP 1 Score: 137.887 bits (346), Expect = 1.786e-35
Identity = 133/444 (29.95%), Postives = 208/444 (46.85%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRIN--------------EVFENXXXXXXXXXXXXXXAPYKNPSAKD-----ERDL-HLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRFKT-PLNIVRNRPKTNQSKTK----VPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTP--VEIPDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTS---SRSIMSPAAIKLLSRMTPSTPKSFISTRPNSVYSLNVKSTPSTRRYGSSTPG-------------------NPASITDNLLDI 1306
            ++DE+++I+ L+ II RDFFPD   L+ Q  Y +A +  D   M+EI +K                     FE      +S  S  + +       KD     E+DL  LD +LSK TSEDN S+  + +   ++   + +W ++A  EY +   ++L      P+      +  K+  +  QYK  N + + P   E   ++ LF    KP E++Y+NTRF+  P     N+ +  Q+         GK+G DGKEL  + +P+V G+   G       +      TWGEI+ TP  +E  D+P+V R     F+I EP  RE+L  +MA++ A KN+ KKQ+AL +V  NL   T    S + +SPA  +L++R +        S   +     +   +P+ R  G+ TP                    +PASITDNLL +
Sbjct:   34 ILDEEQYIESLEKIIQRDFFPDVSKLQAQKDYLEAEENGDLERMREIAIKYGSAMAKYTPRTYVPHVTPSTFETPDGRSASPSSSQSKSRAAREDGKDGEKASEKDLPSLDRFLSKNTSEDNASFEQIMELAEDKDKLRHAWLYEAENEYKERHEQNLAL----PSSEKQALECTKAGLETWQYKAKNSLMYYP---EGEKDDTLF---KKPREVLYKNTRFEDDPFCKALNKSQIQQAAALNAQFKQGKVGPDGKELLPHESPKVNGYGYEGAPSPAPGVAESPLMTWGEIESTPFRLEGSDTPLVERSHGPSFKIPEPGRRERLGLKMANEAAAKNRAKKQEALRKVTENLASLTPKGLSPAALSPALQRLVNRSS--------SKYTDKALRASYTPSPAHRSLGAKTPSGGLTTLTPTPTKTRTPASQDPASITDNLLQL 459
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Zebrafish
Match: ess2 (ess-2 splicing factor homolog [Source:ZFIN;Acc:ZDB-GENE-030131-2843])

HSP 1 Score: 137.887 bits (346), Expect = 1.786e-35
Identity = 133/444 (29.95%), Postives = 208/444 (46.85%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRIN--------------EVFENXXXXXXXXXXXXXXAPYKNPSAKD-----ERDL-HLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRFKT-PLNIVRNRPKTNQSKTK----VPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTP--VEIPDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTS---SRSIMSPAAIKLLSRMTPSTPKSFISTRPNSVYSLNVKSTPSTRRYGSSTPG-------------------NPASITDNLLDI 1306
            ++DE+++I+ L+ II RDFFPD   L+ Q  Y +A +  D   M+EI +K                     FE      +S  S  + +       KD     E+DL  LD +LSK TSEDN S+  + +   ++   + +W ++A  EY +   ++L      P+      +  K+  +  QYK  N + + P   E   ++ LF    KP E++Y+NTRF+  P     N+ +  Q+         GK+G DGKEL  + +P+V G+   G       +      TWGEI+ TP  +E  D+P+V R     F+I EP  RE+L  +MA++ A KN+ KKQ+AL +V  NL   T    S + +SPA  +L++R +        S   +     +   +P+ R  G+ TP                    +PASITDNLL +
Sbjct:   34 ILDEEQYIESLEKIIQRDFFPDVSKLQAQKDYLEAEENGDLERMREIAIKYGSAMAKYTPRTYVPHVTPSTFETPDGRSASPSSSQSKSRAAREDGKDGEKASEKDLPSLDRFLSKNTSEDNASFEQIMELAEDKDKLRHAWLYEAENEYKERHEQNLAL----PSSEKQALECTKAGLETWQYKAKNSLMYYP---EGEKDDTLF---KKPREVLYKNTRFEDDPFCKALNKSQIQQAAALNAQFKQGKVGPDGKELLPHESPKVNGYGYEGAPSPAPGVAESPLMTWGEIESTPFRLEGSDTPLVERSHGPSFKIPEPGRRERLGLKMANEAAAKNRAKKQEALRKVTENLASLTPKGLSPAALSPALQRLVNRSS--------SKYTDKALRASYTPSPAHRSLGAKTPSGGLTTLTPTPTKTRTPASQDPASITDNLLQL 459
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Xenopus
Match: ess2 (ess-2 splicing factor homolog [Source:NCBI gene;Acc:100144733])

HSP 1 Score: 127.872 bits (320), Expect = 1.135e-31
Identity = 127/441 (28.80%), Postives = 204/441 (46.26%), Query Frame = 2 
Query:  140 KGVVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRI--------------NEVFENXXXXXXXXXXXXXXAPYKNP-SAKDERDL----HLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXX-XXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQSKT----KVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEI--PDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNR--PTSSRSIMSPAAIKLLSRM-------------TPSTPKSFISTRPNSVYSLNVKSTPSTRRYGSSTP--GNPASITDNLLDI 1306
            K V+ E+ +I +LQ II RDFFPD E L  Q +Y +A +  D   M++I +K                     FE       +    +     +    A  E+++     LD +L++ TSEDN S+  + +   E++ +K +W ++A +EY +   ++L     E+ AI  GK     +     +YK  N + + P  V    ++ +F    KP E+++ NTR  K P +   ++ +  Q+         GK+G DGKEL    +P+V GF  +        +      TWGE++ TP  I   ++P + +     F+I EP  RE+L  +MA++ A KN+ KK++AL +V  NL    P      MSPA  +L++R              TPS P    +    +   L+  +   T R  S TP   +P SITDNLL +
Sbjct:   41 KKVLCEETYIQNLQKIIQRDFFPDVEKLRAQKEYLEAEECGDLEKMRQISIKFGSTLGKSAQDTPLPYVTPATFETPAGVPGTPSMATVQRTGEEADGAITEKNVDKLPGLDNFLARHTSEDNASFEQIMEVAKEKEKSKHAWLYEAEEEYKERLQKNLALPSAEMQAIECGK-----AGLDTWEYKAQNSLMYYPAGV--PDKDNIF---KKPREVVHRNTRLQKDPFSQALSKTQLQQAAALNAQYKQGKVGPDGKELIPQESPKVNGFGFVATPSPAPGVNESPLMTWGEVESTPFRIDGSETPYMEKTPGPSFKILEPGRRERLGLKMATEAAAKNRAKKEEALRKVTENLASLTPKGLNPSMSPALQRLVNRTSNKYTDKALRASYTPS-PSHTATPAYKTPRGLHTPTVTPTARTASQTPVAPDPTSITDNLLHL 470
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Xenopus
Match: ess2 (ess-2 splicing factor homolog [Source:NCBI gene;Acc:100144733])

HSP 1 Score: 122.094 bits (305), Expect = 1.010e-29
Identity = 124/433 (28.64%), Postives = 199/433 (45.96%), Query Frame = 2 
Query:  164 FIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRI--------------NEVFENXXXXXXXXXXXXXXAPYKNP-SAKDERDL----HLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXX-XXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQSKT----KVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEI--PDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNR--PTSSRSIMSPAAIKLLSRM-------------TPSTPKSFISTRPNSVYSLNVKSTPSTRRYGSSTP--GNPASITDNLLDI 1306
            F+ +LQ II RDFFPD E L  Q +Y +A +  D   M++I +K                     FE       +    +     +    A  E+++     LD +L++ TSEDN S+  + +   E++ +K +W ++A +EY +   ++L     E+ AI  GK     +     +YK  N + + P  V    ++ +F    KP E+++ NTR  K P +   ++ +  Q+         GK+G DGKEL    +P+V GF  +        +      TWGE++ TP  I   ++P + +     F+I EP  RE+L  +MA++ A KN+ KK++AL +V  NL    P      MSPA  +L++R              TPS P    +    +   L+  +   T R  S TP   +P SITDNLL +
Sbjct:   37 FMQNLQKIIQRDFFPDVEKLRAQKEYLEAEECGDLEKMRQISIKFGSTLGKSAQDTPLPYVTPATFETPAGVPGTPSMATVQRTGEEADGAITEKNVDKLPGLDNFLARHTSEDNASFEQIMEVAKEKEKSKHAWLYEAEEEYKERLQKNLALPSAEMQAIECGK-----AGLDTWEYKAQNSLMYYPAGV--PDKDNIF---KKPREVVHRNTRLQKDPFSQALSKTQLQQAAALNAQYKQGKVGPDGKELIPQESPKVNGFGFVATPSPAPGVNESPLMTWGEVESTPFRIDGSETPYMEKTPGPSFKILEPGRRERLGLKMATEAAAKNRAKKEEALRKVTENLASLTPKGLNPSMSPALQRLVNRTSNKYTDKALRASYTPS-PSHTATPAYKTPRGLHTPTVTPTARTASQTPVAPDPTSITDNLLHL 458
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Mouse
Match: Ess2 (ess-2 splicing factor [Source:MGI Symbol;Acc:MGI:107854])

HSP 1 Score: 150.599 bits (379), Expect = 4.517e-40
Identity = 134/450 (29.78%), Postives = 213/450 (47.33%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKDERDLH---------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQSKT----KVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTP--VEIPDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNR--PTSSRSIMSPAAIKLLSRMTPS-TPKSF-ISTRPNSVYSLNVKSTPSTRRYGSSTPG-----------NPASITDNLLDI 1306
            V+DE+++I+ LQ +I RDFFPD E L+ Q +Y +A +  D   M++I +K             +     S     PY  P+  +  ++H                                 LD +LS++TSEDN S+ ++ +   E+   + +W ++A +E++    +  +   ELP+      +  ++  +  +YK  N + + P  V    EE+LF    KP +I+++NTRF + P +   +R +  Q+         GK+G DGKEL    +PRV GF  +        +      TWGE++ TP  VE  +SP V R     F+I EP  RE+L  +MA++ A KN+ KKQ+AL RV  NL    P      MSPA  +L+SR     T ++   S  P+   S ++K+     +  +STP            +PASITDNLL +
Sbjct:   40 VLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFG-----------SALGKISREPPPPYVTPATFETPEVHPGSAVLGNKPRPQGRDLDDGEAGEEEEKEPLPSLDVFLSQYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFE----KRQKDNLELPSAEHQAIESSQAGVETWKYKAKNSLMYYPEGV--PDEEQLF---KKPRQIVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSSHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQL 469
[Close]
BLAST of Ess-2 splicing factor homolog vs. Ensembl Mouse
Match: Ess2 (ess-2 splicing factor [Source:MGI Symbol;Acc:MGI:107854])

HSP 1 Score: 150.214 bits (378), Expect = 6.337e-40
Identity = 134/451 (29.71%), Postives = 213/451 (47.23%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKDERDLH----------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQSKT----KVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTP--VEIPDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNR--PTSSRSIMSPAAIKLLSRMTPS-TPKSF-ISTRPNSVYSLNVKSTPSTRRYGSSTPG-----------NPASITDNLLDI 1306
            V+DE+++I+ LQ +I RDFFPD E L+ Q +Y +A +  D   M++I +K             +     S     PY  P+  +  ++H                                  LD +LS++TSEDN S+ ++ +   E+   + +W ++A +E++    +  +   ELP+      +  ++  +  +YK  N + + P  V    EE+LF    KP +I+++NTRF + P +   +R +  Q+         GK+G DGKEL    +PRV GF  +        +      TWGE++ TP  VE  +SP V R     F+I EP  RE+L  +MA++ A KN+ KKQ+AL RV  NL    P      MSPA  +L+SR     T ++   S  P+   S ++K+     +  +STP            +PASITDNLL +
Sbjct:   40 VLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFG-----------SALGKISREPPPPYVTPATFETPEVHPGSAVLGNKPRPQGRDLDDAGEAGEEEEKEPLPSLDVFLSQYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFE----KRQKDNLELPSAEHQAIESSQAGVETWKYKAKNSLMYYPEGV--PDEEQLF---KKPRQIVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSSHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQL 470
[Close]
BLAST of Ess-2 splicing factor homolog vs. UniProt/SwissProt
Match: sp|Q96DF8|ESS2_HUMAN (Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 4.504e-40
Identity = 135/450 (30.00%), Postives = 217/450 (48.22%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKDERDLH---------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQSKT----KVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXX--XXXXXXWGEIDGTP--VEIPDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNR--PTSSRSIMSPAAIKLLSRMTPS-TPKSF-ISTRPNSVYSLNVKSTPSTRRYGSSTPG-----------NPASITDNLLDI 1306
            V+DE+++I+ LQ +I RDFFPD E L+ Q +Y +A +  D   M++I +K             +     S     PY  P+  +  ++H                                 LD +LS++TSEDN S+ ++ +   ER   + +W ++A +E++  + ++LE     P+      +  +++ +  +YK  N + + P  V    EE+LF    KP +++++NTRF + P +   +R +  Q+         GK+G DGKEL    +PRV GF  +           +P  TWGE++ TP  VE  ++P V R     F+I EP  RE+L  +MA++ A KN+ KKQ+AL RV  NL    P      MSPA  +L+SR     T ++   S  P+   S ++K+  S  +  +STP            +PASITDNLL +
Sbjct:   37 VLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFG-----------SALGKMSREPPPPYVTPATFETPEVHAGTGVVGNKPRPRGRGLEDGEAGEEEEKEPLPSLDVFLSRYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEKRQKDNLEL----PSAEHQAIESSQASVETWKYKAKNSLMYYPEGV--PDEEQLF---KKPRQVVHKNTRFLRDPFSQALSRCQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPMMTWGEVENTPLRVEGSETPYVDRTPGPAFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSTHLKTPASGLQTPTSTPAPGSATRTPLTQDPASITDNLLQL 466
[Close]
BLAST of Ess-2 splicing factor homolog vs. UniProt/SwissProt
Match: sp|O70279|ESS2_MOUSE (Splicing factor ESS-2 homolog OS=Mus musculus OX=10090 GN=Ess2 PE=1 SV=2)

HSP 1 Score: 150.599 bits (379), Expect = 3.160e-39
Identity = 134/450 (29.78%), Postives = 213/450 (47.33%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKDERDLH---------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQSKT----KVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTP--VEIPDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNR--PTSSRSIMSPAAIKLLSRMTPS-TPKSF-ISTRPNSVYSLNVKSTPSTRRYGSSTPG-----------NPASITDNLLDI 1306
            V+DE+++I+ LQ +I RDFFPD E L+ Q +Y +A +  D   M++I +K             +     S     PY  P+  +  ++H                                 LD +LS++TSEDN S+ ++ +   E+   + +W ++A +E++    +  +   ELP+      +  ++  +  +YK  N + + P  V    EE+LF    KP +I+++NTRF + P +   +R +  Q+         GK+G DGKEL    +PRV GF  +        +      TWGE++ TP  VE  +SP V R     F+I EP  RE+L  +MA++ A KN+ KKQ+AL RV  NL    P      MSPA  +L+SR     T ++   S  P+   S ++K+     +  +STP            +PASITDNLL +
Sbjct:   40 VLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFG-----------SALGKISREPPPPYVTPATFETPEVHPGSAVLGNKPRPQGRDLDDGEAGEEEEKEPLPSLDVFLSQYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFE----KRQKDNLELPSAEHQAIESSQAGVETWKYKAKNSLMYYPEGV--PDEEQLF---KKPRQIVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSSHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQL 469
[Close]
BLAST of Ess-2 splicing factor homolog vs. UniProt/SwissProt
Match: sp|O44424|ESS2_DROME (Splicing factor ESS-2 homolog OS=Drosophila melanogaster OX=7227 GN=Es2 PE=1 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 1.955e-24
Identity = 129/415 (31.08%), Postives = 183/415 (44.10%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLK--LNRI----------NEVFENXXXXXXXXXXXXXXAPYKNPSAKDE--------------RD----LHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAI-TDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKPEIMYENTRFKTPLNIVRNRPKTNQSKTKVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEI--PDSPI----VSRFRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSI-----MSPAAI-----KLLSRMTP---STPKSFISTRPNSVYSLNVKST 1234
            ++ E+K+I+++  II RDFFPD E L  Q  Y DA   +DF  M EI+ +  L RI          N     +      S++  ++ P  N  A D               RD    L LD +L K+TSEDN S+ ++    IE    KL   +     ++ L  E L+    LP+I T  +        +   Y   N + + P  VE + EER+ LA  K  I +  TR   P         T +   +VP + G  G    +  TP+V GF +L               TWGEIDGTP  +   D+P+       FRI E S RE +A  +A +V+ + +++KQ ALD  R N+  P    ++     MSPAA      KL  R TP    TP S +S R   V    V+ST
Sbjct:   50 ILTEEKYIEEMSKIIQRDFFPDLERLRAQNDYLDAESRRDFVQMAEIRERYSLGRISGTGRSTSRRNNAMSPATFETPVSQAKCSNTPLPNSRATDTPFSTDGSEKSDAEGRDTTAKLSLDAFLQKYTSEDNQSFQEI----IETAEAKLRQKYAVLYNHEKLSAEQLQRALMLPSIETQFEEPDPLRKIETWNYTNMNSIMYVPDGVEYTEEERVQLAERKQSIQHNATRL--PDEAKHREMDTKKLNDEVP-QNGAGG----ATATPKVRGFDLLRSPSPRPGEAFSPIMTWGEIDGTPFRLDGGDTPLRPTQGPSFRINENSRRENIAIALAERVSERMRNQKQMALDTARRNIGSPLIRTNMERLASMSPAAQLLATGKLGIRGTPRLRHTP-SPMSGRKRKVTPGVVRST 452
[Close]
BLAST of Ess-2 splicing factor homolog vs. UniProt/SwissProt
Match: sp|P34420|ESS2_CAEEL (Splicing factor ESS-2 OS=Caenorhabditis elegans OX=6239 GN=ess-2 PE=3 SV=2)

HSP 1 Score: 93.2041 bits (230), Expect = 4.456e-19
Identity = 119/468 (25.43%), Postives = 181/468 (38.68%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAP--------YKNPSAKDERDLH------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKIL-----QYKIFNPVFFNPGSVELSAEERLFLA-GSKPEIMYENTRFK-----TPLNIVRNRPKTNQSKTKVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEIPDSPIVSR---------FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRS---------NLNRPTSSRSIMSPAAIKLLS-----RMTPSTPKSFI----------------STRPNSVYSLNVKSTPSTRRYGSSTPGNPA 1279
            VV E+K+I  L  II +D+FP  + ++ Q +Y +A+  +D   +KE+Q+K      V  +       +   +T AP           PS+      H                              L  YL+K+TSEDN S+ +L K   ER+  +  W +KA +E++   +       E       K+     +N+ L      YK +N V FNP    L+  E    A   + EI    TRF       P +    R   + +     GK+   G E+    TP    F +L   +           TWGEIDGTP  + D+P V+          F+I E   REK+A  M   +A K +DK++ A+                 R +   + +SPAA KL +     +M P+    F                 ST P S +S    +  S+   G+ TPG P 
Sbjct:   41 VVPEEKYIAGLDKIIEKDYFPHLKKMQAQKEYLEAVANKDINKIKELQMKFCSTGSVRTDRSFRTPITTRSTTEAPDVSSFDADTPGPSSASTSSAHDWMQSPMPFANEEGDNEALNRKRKKKKEETLTSYLNKYTSEDNASFEELAKVMREREDARRPWVYKAEEEHNKNLVTRQAIAAEADVQLALKHAVDADDNRPLNVDNWAYKAWNTVLFNPDGAALTPAEIADAARKQQTEINKRGTRFPDSGKLKPSDEAMTRAAVSHALANA-GKVDFLGNEV----TP-ANSFKLLETPNPNPDDMDSPLMTWGEIDGTPFRL-DAPDVTEHSLPGAAPVFKIPEVPYREKIAQSMNDSIAAKYRDKRKVAMRAAEGAHFSRTPGFGSKRVSDKLAQLSPAAQKLATKKLGLKMLPAHKSPFASPKIMSNWSRPSSSKRSTTPGSAWSRGSTTPGSSWSQGAQTPGTPG 501
[Close]
BLAST of Ess-2 splicing factor homolog vs. TrEMBL
Match: A0A2K5H7W1 (Uncharacterized protein OS=Colobus angolensis palliatus OX=336983 PE=4 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 2.449e-39
Identity = 138/460 (30.00%), Postives = 220/460 (47.83%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKDERDLH---------------------------------LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQ----SKTKVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXX--XXXXXXWGEIDGTP--VEIPDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNR--PTSSRSIMSPAAIKLLSRMTPS-TPKSF-ISTRPNSVYSLNVKSTPSTRRYGSSTPG-----------NPASITDNLLDI*YYCYSINIF 1336
            V+DE+++I+ LQ +I RDFFPD E L+ Q +Y +A +  D   M++I +K             +     S     PY  P+  +  ++H                                 LD +LS +TSEDN S+ ++ +   ER   + +W ++A +E++  + ++LE     P+      +  ++  +  +YK  N + + P  V    EE+LF    KP +++++NTRF + P +   +R +  Q    S     GK+G DGK+L    +PRV GF  +           +P  TWGE++ TP  VE  ++P V R     F+I EP  RE+L  +MAS+ A KN+ KKQ+AL RV  NL    P   +  MSPA  +L+SR     T ++   S  P+   S ++K+  S  +  +STP            +PASITDNLL +   C + + F
Sbjct:   37 VLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLEQMRQIAIKFG-----------SALGKMSREPPPPYVTPATFETPEVHTGTGVVGSKPRPHGRGPEDGEAGEEEEKEPLPSLDVFLSHYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEKRQKDNLEL----PSAEHQAIESSQAGVETWKYKAKNSLMYYPEGV--PDEEQLF---KKPRQVVHKNTRFLRDPFSQALSRCQLQQAAALSAQHKQGKVGPDGKKLIPQESPRVGGFGFVATPSPAPGVNESPVMTWGEVENTPLRVEGSETPYVDRTPGPAFKILEPGRRERLGLKMASEAAAKNRAKKQEALRRVTENLASLTPKGLKPAMSPALQRLVSRTASKYTDRALRASYTPSPARSTHLKTPASGLQTPTSTPAPGSATRTPLTQDPASITDNLLQLPARCKASDFF 476
[Close]
BLAST of Ess-2 splicing factor homolog vs. TrEMBL
Match: A0A195CS64 (Protein DGCR14 like protein OS=Cyphomyrmex costatus OX=456900 GN=ALC62_05663 PE=4 SV=1)

HSP 1 Score: 157.147 bits (396), Expect = 4.210e-39
Identity = 135/437 (30.89%), Postives = 216/437 (49.43%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKD----------------ERDLHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKPEIMYENTRFKT-PLNIVRNRPKTNQ---SKTKV-PGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEI--PDSPIVS-----RFRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSI-----MSPAAIKLLSRM-----TPSTPKSFISTRPNSVYSLNVKSTP----------STRRYGSSTPGNPASITDNLLDI 1306
            ++DED +I+ +  II +DFFP  E L+ Q +Y DA++  D   M+E+  K +    V E   S  +       +   ++P   +                E  + LD+YLS  TSEDN S+ ++  +   ++  K +W ++ A+E     +        +PAI      KQ  +     YK  N + + P  VEL+A+E++ LA  K  IM+ENTR +T P N  +N+   ++   S++K   GKIG DGKE+  N TPRV GF+ +               TWG+I+GTP  +   D+P++       FRI EP +RE+LA ++A K   + +D+K +AL+  R +L  P+   +I     MSPAA +L ++      TPS P+    +R +SV  +   +TP          S +   +ST      +TDNLL++
Sbjct:   42 ILDEDTYIEKMSDIIQKDFFPHLEKLQAQNQYLDALEQNDMNRMRELYAKYSSGQPVTERPISPATFETPLRRAESDESPPTTEALSQKTSVESINRDDNENKIGLDDYLSTHTSEDNASFEEMMVEAENKRKLKYAWLYE-AEEKSKAWLAIDGPVTNVPAIESNLRPKQVDS---WAYKNKNYIMYIPDGVELTAKEKIELAKKKQTIMHENTRLRTNPFNEQQNKETIDELAKSQSKANDGKIGVDGKEVVRNATPRVNGFSFVATPSPRPGECESPLMTWGQIEGTPFRLDGGDTPLLRTNQGPSFRIAEPPKREQLALQLAEKAGERYRDRKNKALEAARRSLATPSPRSTIDRLSTMSPAARRLATQRLRVLNTPS-PRRTPLSRTSSVGGIKTPNTPRANVSVKEITSQKSETNSTRIQGPVLTDNLLNL 473
[Close]
BLAST of Ess-2 splicing factor homolog vs. TrEMBL
Match: A0A151JYC3 (Protein DGCR14 like protein OS=Trachymyrmex septentrionalis OX=34720 GN=ALC56_04134 PE=4 SV=1)

HSP 1 Score: 158.303 bits (399), Expect = 9.879e-39
Identity = 135/431 (31.32%), Postives = 219/431 (50.81%), Query Frame = 2 
Query:  113 LKDMT-----LGRVK-------GVVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKD-----------------ERDLHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKA---AKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKPEIMYENTRFKT-PLNIVRNRPKTNQ---SKTKV-PGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEI--PDSPIVS-----RFRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSI-----MSPAAIKLLSRM-----TPSTPKSFISTRPNSVYSLNVKSTP 1237
            +KD+T     +G VK        ++DED +I+ +  II +DFFP  E L+ Q +Y +A++  D   M+E+  K +    + E   S  +       +   ++P   +                 E  + LD+YLS  TSEDN S+ ++  +   ++  K +W ++A   +K +  +   S  +  ++PAI  G N + K  +    YK  N + + P  VEL+A E++ LA  K  IM+ENTR +T P N  +N+   ++   S+++   GKIG DGKE+  N TPRV GF+ +               TWG+I+GTP  +   D+P++       FRI EP +RE+LA ++A K   +++D+K +AL+  R +L  P+   +I     MSPAA +L ++      TPS P+   S+R  SV SL   +TP
Sbjct:  146 IKDLTVFKKPIGSVKRSKNVQPKILDEDTYIEKMSDIIQKDFFPHLEKLQAQNQYLEALEQNDMNRMRELYAKYSSGRPITERPISPATFETPLRRTESAESPPTTEASSQKTDVVESVNRDGTESKIGLDDYLSNHTSEDNASFEEMMIEAENKRKLKYAWLYEAEDKSKAWLAIDGSSTTTTPDVPAI-QGSNPRPKQVDS-WTYKNKNYIMYIPDGVELTAGEKIELAKKKQTIMHENTRLRTNPFNEQQNKETIDELAKSQSRANDGKIGVDGKEVVRNATPRVNGFSFVATPSPRPGECESPLMTWGQIEGTPFRLDGGDTPLLRTSQGPSFRIAEPPKREQLALQLAEKAGERHRDRKNKALEAARRSLATPSPRSTIDRLSTMSPAARRLATQKLRISNTPS-PRRTPSSRTPSVGSLRTPNTP 573
[Close]
BLAST of Ess-2 splicing factor homolog vs. TrEMBL
Match: A0A195E3Q4 (Protein DGCR14 like protein OS=Trachymyrmex cornetzi OX=471704 GN=ALC57_07980 PE=4 SV=1)

HSP 1 Score: 157.147 bits (396), Expect = 1.156e-38
Identity = 134/431 (31.09%), Postives = 219/431 (50.81%), Query Frame = 2 
Query:  113 LKDMT-----LGRVK-------GVVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKD-----------------ERDLHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKA---AKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKPEIMYENTRFKT-PLNIVRNRPKTNQ---SKTKV-PGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEI--PDSPIVS-----RFRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSI-----MSPAAIKLLSRM-----TPSTPKSFISTRPNSVYSLNVKSTP 1237
            +KD+T     +G VK        ++DED +I+ +  II +DFFP  E L+ Q +Y +A++  D   M+E+  K +    V E   S  +       +   ++P   +                 E  + LD+YLS  TSEDN S+ ++  +   ++  K +W ++A   +K +  +   S  +  ++PAI  G N + K  +    YK  N + + P  VEL+AEE++ LA  K  IM+ENTR +T P N  +N+   ++   S+++   GKIG DGKE+  N TPRV GF+ +               TWG+I+GTP  +   D+P++       FRI EP +RE+LA ++A K   +++D+K +AL+  R +L  P+   +I     MSPAA +L ++      TPS  ++ +S  P SV  +   +TP
Sbjct:   79 IKDLTVFKKPIGSVKRSKSVQPKILDEDTYIEKMSDIIQKDFFPHLEKLQAQNQYLEALEQNDMNRMRELYAKYSSGRPVTERPISPATFETPLRRTESAESPPTTEASSQKTDIVESVNRNGTESKIGLDDYLSNHTSEDNASFEEMMIEAENKRKLKYAWLYEAEDKSKAWLAIDGSSTTTTPDVPAI-QGSNPRPKQVDS-WTYKNKNYIMYIPDGVELTAEEKIELAKKKQTIMHENTRLRTNPFNEQQNKETIDELAKSQSRANDGKIGVDGKEVVRNATPRVNGFSFVATPSPRPGECESPLMTWGQIEGTPFRLDGGDTPLLRTSQGPSFRIAEPPKREQLALQLAEKAGERHRDRKNKALEAARRSLATPSPRSTIDRLSTMSPAARRLATQKLRISNTPSPRRTPLSRTP-SVGGIRTPNTP 506
[Close]
BLAST of Ess-2 splicing factor homolog vs. TrEMBL
Match: G3HER2 (DGCR14 OS=Cricetulus griseus OX=10029 GN=CgPICR_002275 PE=4 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 1.868e-38
Identity = 139/439 (31.66%), Postives = 219/439 (49.89%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLK----LNRINE----------VFENXXXXXXXXXXXXXXAPYK----NPSAKDERDLH----LDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRF-KTPLNIVRNRPKTNQSKT----KVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTP--VEIPDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNR--PTSSRSIMSPAAIKLLSRMTPS-TPKSF-ISTRPNSVYSLNVKSTPSTRRYGSSTPG-----------NPASITDNLLDI 1306
            V+DE+++I+ LQ +I RDFFPD E L+ Q +Y +A +  D   M++I +K    L +I+            FE    +  S    S   P      +  A+DE +      LD +LS++TSEDN S+ ++ +   E+   + +W ++A +E++    +  +   ELP+      +  ++  +  +YK  N + + P  V    EE+LF    KP +++++NTRF + P +   +R +  Q+         GK+G DGKEL    +PRV GF  +        M      TWGE++ TP  VE  +SP V R     F+I EP  RE+L  +MA++ A KN+ KKQ+AL RV  NL    P      MSPA  +L+SR     T ++   S  P+   S ++K+     +  +STP            +PASITDNLL +
Sbjct:   37 VLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKISREPPPPYVTPATFETPEVHTGSGVVGSKLRPQGRDLDDGEARDEEEKEPLPSLDVFLSRYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFE----KRQKDNLELPSAEHQAIESSQAGVETWKYKAKNSLMYYPEGV--PDEEQLF---KKPRQVVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGMNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSTHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQL 466
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Cavefish
Match: ess2 (ess-2 splicing factor homolog [Source:NCBI gene;Acc:103030684])

HSP 1 Score: 130.183 bits (326), Expect = 8.286e-33
Identity = 126/449 (28.06%), Postives = 207/449 (46.10%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPS-----------------------------AKDERDL-HLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRFKT-PLNIVRNRPKTNQSKT-----KVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEI--PDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTS---SRSIMSPAAIKLLSR-------------MTPSTPKSFISTRPNSVYSLNVKSTPSTRRYGSSTPGNPASITDNLLDI 1306
            ++ E+++I +L+ II RDFFPD   L+ Q  Y +A +  D   M+EI +K       +           +  T  PY  PS                              K+E++L  LD +L+K TSEDN S+  +     +++  K +W ++A +E+     +  E    LP+      +  K+  +  +YK  N + + P  V+   ++ +F    KP E++Y+NTRF   P     N+ +  Q+       K+ GK+G DGKEL  + +P+V G+   G       ++     TWGEI+ TP  +   ++PI+ R     F+I EP  RE+L  +MA++VA KN+  KQ+AL +V  NL   T    S + +SPA  +L++R              TPS     +  +           TP+  +  +    +PASITD+LL +
Sbjct:   25 ILQEEQYIQNLEKIIQRDFFPDVSKLQAQKDYLEAEELGDLERMREIAIKYGTAMAKY-----------TPRTYVPYVTPSTFETPDARAASPSTSHTKPRTSENGGKDGGKEEKELPSLDRFLAKNTSEDNASFEQIMDLAKDKEKLKNAWLYEAEEEF----KKRHEENLALPSSEQQALECTKAGVETWEYKARNALMYYPEGVK---DDAVF---KKPREVLYKNTRFDVDPFCKALNKSQIQQAAALNAQFKL-GKVGPDGKELLPHESPKVNGYGFEGTPSPAPGVSESPLMTWGEIESTPFRLDGSETPIIERSHGPSFKIPEPGRRERLGLKMANEVAAKNRANKQEALRKVTENLASLTPKGLSPAALSPALQRLVNRSSSKYTDKALRASYTPSPSHRGLGAKTPHGGPATPSGTPTPSKTKTPITHDPASITDDLLQL 451
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Nematostella
Match: EDO41932 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S351])

HSP 1 Score: 116.701 bits (291), Expect = 1.489e-28
Identity = 133/444 (29.95%), Postives = 204/444 (45.95%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYK------------------NPSAKDERDLHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQ------KSNNKILQYKIFNPVFFNPGSVELSAEERLF-LAGSKPEIMYENTRF-KTPL-NIVRNRPKTNQSKTKVP---GKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXX--XXWGEIDGTPVEI--PDSPIVSR----FRIQEPSEREKLANEMASKVARKNKDKKQQALDR----VRSNLNRPTSSRSI--MSPAAIKLLS-----RM----------TPSTPKSFISTRPNSVYSLNVKSTPSTRRYGSSTPGNPASITDNLL 1300
            V+DED ++  +  II RDFFP+   L  Q +Y DA++  D   ++EI  +    N+    +      + S     P +                  +   KD  +L LD++L+K TSEDN S+  + +   E+   K  W +K  +E+ +++  SL       A+  GK  +Q       +  +   YK  N + + P   E S  E++   A    E+M+ENTRF + P  +   +    + S  K+    GKIG DG+ +  + TP+V GF  +        +      TWG IDGTP  +   D+P  S     FR+ EP  REKL + +A +V+R+++DKK+ A  R    + S+  +P+S + +  MSPAA  L S     RM          TPS P       P S    +   TP T   G STP   +S+TDNLL
Sbjct:   28 VLDEDTYVQSVDKIIQRDFFPELSKLRAQHEYLDAVEHNDTERLREISSRYQS-NQTPHLATPATFDTPSTIQGTPLRQGEVSSMNREQPNQSQEGDKRTKDPSNLPLDKFLAKHTSEDNASFEQIMETAREKHREKYEWLYKKEEEHSEIQQASL-------ALPSGKEGEQLMIEQRPAMVETWTYKNKNALMYVPEGTEHSVIEQIEKKAKGTQEVMHENTRFSRNPFPDASCSGMLADASAAKLAQQQGKIGVDGQVIAPSETPKVNGFGFIATPSPAPGVDASPLMTWGSIDGTPFRLDGSDTPKPSTPGPGFRMPEPKPREKLGHALAERVSRQHRDKKRDARARAAAMIGSSQGQPSSVKRLNSMSPAAQLLASKRLGIRMGTDKALQASYTPS-PSHRGEATPKSTPGHSTPRTPKTP--GMSTPTRTSSLTDNLL 460
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Medaka
Match: ess2 (ess-2 splicing factor homolog [Source:NCBI gene;Acc:101167808])

HSP 1 Score: 124.02 bits (310), Expect = 1.344e-30
Identity = 124/440 (28.18%), Postives = 206/440 (46.82%), Query Frame = 2 
Query:  146 VVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKL--NRINEVFENXXXXXXXXXXXXXXAPYKNPSA----------------KDERDLHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP-EIMYENTRFKT-PLNIVRNRPKTNQSKTKVP----GKIGHDGKELDSNGTPRVAGFTI--LGRMDXXXXXXXXXXWGEIDGTPVEI--PDSPIVSR-----FRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSIMSPAAIKLLSRMTPSTPKSFISTRPNSVYSLNVKSTPSTRRYGSSTPGNP--------------------ASITDNLLDI 1306
            V+DE+++I+ L+ II RDFFPD   L+ Q  Y +A +  D   M+EI ++   N      ++S    + +   +     K+PS+                +D++  +LD +L+K TSEDN S+  + +   +++  K +W ++A  E+     +  E+   LP       +  K+  +  +YK  N + + P  V+   ++ +F    KP E++++NTRF   P +   N+ +  Q+         GK+G DGKEL    +P V G++      +    + +P  TWGEI+ TP  +   D+P + R     F+I EP  RE+L  +MA++ A KN+ KKQ+AL +V  NL   T     +SPA    L R+   T   +      + Y+     +PS R  G  TP  P                     S+TDNLL +
Sbjct:   40 VLDEEEYIESLEKIIQRDFFPDVTKLQAQRDYLEAEENGDLEKMREISIRFGSNLTKSTPQSSAPYVTPASFETPVGCPKSPSSNHCSKVSEGEHKEDDGEDKKLPNLDRFLAKTTSEDNASFEQIMELAEDKEKLKHAWLYEAEAEF----KQRHENNLALPPAEKAALECVKAGLETWEYKAKNALMYYPEGVK--DDDSVF---KKPREVVHKNTRFSGDPFSNALNKSQIQQAAALNAQFKQGKVGPDGKELIPQESPTVNGYSYERTPLVAPGVSESPLMTWGEIESTPFRLDGSDTPYIERNHGPSFKIPEPGRRERLGLKMANEAAAKNRAKKQEALRKVTENLASLTPKG--LSPALSPALQRLVNRTSSKYTDKALRASYT----PSPSHRGAGCKTPFGPDTPSGTPTPNKVKTPGSQDLTSLTDNLLQL 464
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BLAST of Ess-2 splicing factor homolog vs. Planmine SMEST
Match: SMESG000033822.1 (SMESG000033822.1)

HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0
Identity = 394/395 (99.75%), Postives = 394/395 (99.75%), Query Frame = 2 
Query:  122 MTLGRVKGVVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENXXXXXXXXXXXXXXAPYKNPSAKDERDLHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDXXXXXXXXXXXXPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKPEIMYENTRFKTPLNIVRNRPKTNQSKTKVPGKIGHDGKELDSNGTPRVAGFTILGRMDXXXXXXXXXXWGEIDGTPVEIPDSPIVSRFRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSIMSPAAIKLLSRMTPSTPKSFISTRPNSVYSLNVKSTPSTRRYGSSTPGNPASITDNLLDI 1306
            MTLGRVKGVVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENSRSNESSSKSFSTSAPYKNPSAKDERDLHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDLKMESLESKEELPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKPEIMYENTRFKTPLNIVRNRPKTNQSKTKVPGKIGHDGKELDSNGTPRVAGFTILGRMDTPTTMTPKTTWGEIDGTPVEIPDSPIVSRFRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSIMSPAAIKLLSRMTPSTPKSFISTRPNSVYS NVKSTPSTRRYGSSTPGNPASITDNLLDI
Sbjct:    1 MTLGRVKGVVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFCLMKEIQLKLNRINEVFENSRSNESSSKSFSTSAPYKNPSAKDERDLHLDEYLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDLKMESLESKEELPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKPEIMYENTRFKTPLNIVRNRPKTNQSKTKVPGKIGHDGKELDSNGTPRVAGFTILGRMDTPTTMTPKTTWGEIDGTPVEIPDSPIVSRFRIQEPSEREKLANEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSIMSPAAIKLLSRMTPSTPKSFISTRPNSVYSFNVKSTPSTRRYGSSTPGNPASITDNLLDI 395
The following BLAST results are available for this feature:
BLAST of Ess-2 splicing factor homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ESS29.378e-4130.00ess-2 splicing factor homolog [Source:HGNC Symbol;... [more]
ESS21.295e-1325.00ess-2 splicing factor homolog [Source:HGNC Symbol;... [more]
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ess-29.990e-2125.75Splicing factor ESS-2 [Source:UniProtKB/Swiss-Pro... [more]
ess-23.503e-2025.43Splicing factor ESS-2 [Source:UniProtKB/Swiss-Pro... [more]
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Es21.950e-2531.08gene:FBgn0023506 transcript:FBtr0071198[more]
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ess21.786e-3529.95ess-2 splicing factor homolog [Source:ZFIN;Acc:ZDB... [more]
ess21.786e-3529.95ess-2 splicing factor homolog [Source:ZFIN;Acc:ZDB... [more]
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ess21.135e-3128.80ess-2 splicing factor homolog [Source:NCBI gene;Ac... [more]
ess21.010e-2928.64ess-2 splicing factor homolog [Source:NCBI gene;Ac... [more]
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Ess24.517e-4029.78ess-2 splicing factor [Source:MGI Symbol;Acc:MGI:1... [more]
Ess26.337e-4029.71ess-2 splicing factor [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of Ess-2 splicing factor homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q96DF8|ESS2_HUMAN4.504e-4030.00Splicing factor ESS-2 homolog OS=Homo sapiens OX=9... [more]
sp|O70279|ESS2_MOUSE3.160e-3929.78Splicing factor ESS-2 homolog OS=Mus musculus OX=1... [more]
sp|O44424|ESS2_DROME1.955e-2431.08Splicing factor ESS-2 homolog OS=Drosophila melano... [more]
sp|P34420|ESS2_CAEEL4.456e-1925.43Splicing factor ESS-2 OS=Caenorhabditis elegans OX... [more]
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BLAST of Ess-2 splicing factor homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2K5H7W12.449e-3930.00Uncharacterized protein OS=Colobus angolensis pall... [more]
A0A195CS644.210e-3930.89Protein DGCR14 like protein OS=Cyphomyrmex costatu... [more]
A0A151JYC39.879e-3931.32Protein DGCR14 like protein OS=Trachymyrmex septen... [more]
A0A195E3Q41.156e-3831.09Protein DGCR14 like protein OS=Trachymyrmex cornet... [more]
G3HER21.868e-3831.66DGCR14 OS=Cricetulus griseus OX=10029 GN=CgPICR_00... [more]
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ess28.286e-3328.06ess-2 splicing factor homolog [Source:NCBI gene;Ac... [more]
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO419321.489e-2829.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ess-2 splicing factor homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ess21.344e-3028.18ess-2 splicing factor homolog [Source:NCBI gene;Ac... [more]
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BLAST of Ess-2 splicing factor homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000033822.10.000e+099.75SMESG000033822.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30033747 ID=SMED30033747|Name=Ess-2 splicing factor homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=1340bp
TATCAATTTTAAATTTTCCAATTTTATTACAAATATTTGTATATTGATTC
TAAATTTAAAGTTTTTATAAATTTGTTTAGTTATTCAGTTATTCAGTTAT
TCATAATTATTTTTGAAAGATATGACTTTAGGAAGAGTTAAAGGCGTTGT
TGATGAAGATAAATTTATTGATGATTTACAATTTATAATTAATAGGGATT
TTTTCCCTGATTCAGAATTATTGGAATTGCAATTAAAGTATTATGATGCA
ATGGATGCTCAGGATTTCTGTCTGATGAAAGAAATACAGTTGAAGTTAAA
TAGAATAAATGAAGTTTTTGAAAATAGTAGAAGTAATGAGAGTTCATCAA
AGTCTTTTTCAACTTCAGCTCCATATAAAAATCCAAGTGCAAAAGATGAA
AGAGATCTTCATTTAGACGAATATTTATCAAAATTTACCAGCGAAGATAA
TTTTTCATATTCAGATTTACAAAAGAAAACTATTGAAAGACAACTGAATA
AATTATCCTGGTGGTTTAAAGCAGCTAAGGAATATGACGATTTAAAAATG
GAATCTCTTGAATCCAAAGAAGAACTACCAGCTATAACCGATGGCAAGAA
CAAAAAACAGAAATCAAATAACAAAATTCTTCAATACAAAATATTTAACC
CAGTTTTTTTCAATCCCGGTAGTGTTGAGCTTTCAGCAGAAGAGCGTTTA
TTTTTGGCTGGAAGTAAACCAGAAATAATGTATGAGAATACACGTTTCAA
AACTCCATTGAATATTGTTAGAAACCGTCCTAAAACTAATCAAAGTAAAA
CTAAAGTTCCTGGTAAAATCGGTCACGATGGCAAAGAACTTGATTCAAAT
GGAACACCGAGAGTCGCCGGGTTTACTATTCTTGGTAGAATGGACACCCC
GACTACAATGACACCTAAAACCACATGGGGAGAGATAGATGGAACCCCAG
TTGAAATTCCAGATAGTCCTATCGTTTCGAGATTTAGAATTCAGGAACCT
TCTGAAAGAGAAAAACTAGCCAATGAAATGGCTTCTAAAGTTGCAAGAAA
GAATAAGGATAAGAAACAACAAGCACTGGACAGAGTCAGATCCAATCTCA
ACCGACCGACATCCTCGAGGTCCATTATGTCGCCAGCGGCTATTAAGTTG
CTCTCCAGAATGACCCCATCAACTCCCAAGAGTTTCATTAGCACTCGACC
CAACTCAGTATATTCATTGAATGTGAAAAGCACGCCATCGACCCGAAGAT
ATGGCTCGTCTACGCCTGGCAATCCGGCATCTATTACTGATAATTTGTTG
GACATCTGATATTATTGTTATTCAATAAATATATTCCGAC
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protein sequence of SMED30033747-orf-1

>SMED30033747-orf-1 ID=SMED30033747-orf-1|Name=SMED30033747-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=396bp
MTLGRVKGVVDEDKFIDDLQFIINRDFFPDSELLELQLKYYDAMDAQDFC
LMKEIQLKLNRINEVFENSRSNESSSKSFSTSAPYKNPSAKDERDLHLDE
YLSKFTSEDNFSYSDLQKKTIERQLNKLSWWFKAAKEYDDLKMESLESKE
ELPAITDGKNKKQKSNNKILQYKIFNPVFFNPGSVELSAEERLFLAGSKP
EIMYENTRFKTPLNIVRNRPKTNQSKTKVPGKIGHDGKELDSNGTPRVAG
FTILGRMDTPTTMTPKTTWGEIDGTPVEIPDSPIVSRFRIQEPSEREKLA
NEMASKVARKNKDKKQQALDRVRSNLNRPTSSRSIMSPAAIKLLSRMTPS
TPKSFISTRPNSVYSLNVKSTPSTRRYGSSTPGNPASITDNLLDI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR019148Nuclear_protein_DGCR14_ESS-2
Vocabulary: biological process
TermDefinition
GO:0000398mRNA splicing, via spliceosome
GO:0006397mRNA processing
GO:0007399nervous system development
GO:0008380RNA splicing
Vocabulary: molecular function
TermDefinition
GO:0003674molecular_function
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005681spliceosomal complex
GO:0071013catalytic step 2 spliceosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019148Nuclear protein DGCR14/ESS-2PFAMPF09751Es2coord: 70..343
e-value: 5.1E-32
score: 112.2
coord: 9..83
e-value: 5.8E-11
score: 42.8
IPR019148Nuclear protein DGCR14/ESS-2PANTHERPTHR12940ES-2 PROTEIN - RELATEDcoord: 8..383
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 306..321
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 371..395
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 306..334
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 73..87
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 73..92