Protein unc-80
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033709 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 15Note: Hover over icons to view figure legend
Homology
BLAST of Protein unc-80 vs. Ensembl Human
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:26582]) HSP 1 Score: 742.651 bits (1916), Expect = 0.000e+0 Identity = 447/1313 (34.04%), Postives = 719/1313 (54.76%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF--QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESP--------YRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
E +D +L Y+ V +L+ +++ K A +L E+++ DI P AWELLL D + +AA + +L A+K+P ++ E H + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + +C + + + ++++ K+F + +R Q+ E + K + EE++++ R+ +T I ++A +E + + E ++E N A RRLS + + + RN S+R GS+ +S + V ED+++ + T QP Q VFP+ +CAA +PI+HL++DG+V DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P+ +H+ L ++L + PSFPR A+++EFSL+ GK+L+G+D L K W +L+ +F MPS FPW +I LFLN+FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VYS N L++AI F C QFYILHR PF+LQ+F S++ ++F N + ++D+L+++ + D L+IL+L+ KPLK+LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T + E A LA S++ L+ + + LTR P D+ N++ + + V Q++ LLEEG+ + DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + + + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1616 EGKKDSGMLKYIRLQVMSLSPAPLSLLIKAAPILTEEMYGDIQPAAWELLLSMDEHMAGAAAAMFLLCAVKVPEAVSDMLMSEFHHPETVQRLNAVLKFHTLWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPVLGMPSVPMFDPPW-VPQCSGSVQDPINEDQS-KSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPITQEACYEPTCTPNSEPEEE----------VEEVTNLASRRLSVS-PSCTSSTSHRNYSFRRGSV-WSVRSAVSAEDEEHTTEHTPNHHVPQP---PQAVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELMYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPESQSTHYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMHPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPTAHKQSHVSMLQEDLLRLPSFPRSAIDAEFSLFSDPQAGKELFGLDTLQKSLWIQLLEEMFLGMPSEFPWGDEIMLFLNVFNGALILHPEDSALLRQYAATVINTAVHFNHLFSLSGYQWILPTMLQVYSDYESNPQLRQAIEFACHQFYILHRKPFVLQLFASVAPLLEFPDAANNGPSKGVSAQCLFDLLQSLEGETTDILDILELVKAEKPLKSLDFCYGNEDLTFSISEAIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQVETVPAAREEIAATAALATSLQALLYSVEVLTRPMTAPQMSRCDQGHKGTTTANHTMS-SGVNTRYQEQGAKLHFIRENLHLLEEGQ----GIPREELDERIAREEFR-----RPRESLLNICTEFYKHCGPRLKILQNLAGEPRVIALELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWTAEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVLLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRREGLAESTSQAA 2860 HSP 2 Score: 193.741 bits (491), Expect = 5.479e-48 Identity = 158/519 (30.44%), Postives = 237/519 (45.66%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQD-HKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVS-----TFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W +A+G RL E + + + I DE R L+ DEEE+FLDDSTVNP CP+ALK QLLL ITT+LRET LP+ RT L + + +D D H+ ++I + GV + DS D SLHSS+++L ++G + +K P R+ + G LL + + + SFQ K +L S+R R+GS++ K S Q S + TV + SP S G+S +N+ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y + R+ +SVA
Sbjct: 1168 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNITKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDAIGVRLNELCHGESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSTVNPSKCGCPFALKMAACQLLLEITTFLRETFSCLPRPRTEPLVD-LESCRLRLDPELDRHRYERKISF-------AGVLDENEDSKD-------------------------------SLHSSSHTLK--SDAGVEEKKVP--------------------------------------SRKIRIGGSRLL-QIKGTRSFQ-------VKKGGSLSSIR-----RVGSLKSSKLSRQDSESEAEELQLSQSRDTVTDLEGSPWSASEPSIEPEGMSNAGAEENYHRNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLYGDSVDSLRESSNISSVA 1586 HSP 3 Score: 144.821 bits (364), Expect = 3.295e-33 Identity = 82/235 (34.89%), Postives = 131/235 (55.74%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDR---------------------ENKCSDGIS----------------YLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C +N+R EN+ S G + + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ ++QP ++ FTA VK
Sbjct: 4 RKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDC-NNERFGGTDRGSSWGGSSSAFIHQVENQGSPGQPCQSSSNDEEENNRRKIFQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEHRQPGVSGFTALVK 234 HSP 4 Score: 99.7525 bits (247), Expect = 1.170e-19 Identity = 67/205 (32.68%), Postives = 105/205 (51.22%), Query Frame = 1
Query: 2980 EELNSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQT-----HECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGR 3579
E+ S +SN+ +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ ++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+
Sbjct: 776 EKDESTPVSNHRLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRHQVFRENAQNCLTKLYKLDKMQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNKAGFG--NNFTTVDNKSTA----QNVEGIIVSAMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLAPGK 965 HSP 5 Score: 70.4774 bits (171), Expect = 1.033e-10 Identity = 45/160 (28.12%), Postives = 75/160 (46.88%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW FLDFIV R PIF+ L PF++ K+ PA E E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2860 AYLALKVILVCFERQLGSQWYWLSLQVKEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKL-----------------LAQPA-----ENHEELSARQHIADQLERRFIPRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2997 HSP 6 Score: 63.929 bits (154), Expect = 9.779e-9 Identity = 35/119 (29.41%), Postives = 71/119 (59.66%), Query Frame = 1
Query: 2302 FFDDSPKQEKLSNEQQL-QRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFE--KRIKKKKPDQENSSM 2649
FF++ KL N+ + + EP+ L RS +D+ INY +E+ E + G+ +++ NG ++ +V+LKA++ ++N S RIC+ ++ + CL +G+ ++ +KK ++EN ++
Sbjct: 591 FFNE--HMRKLCNQVPIPEMPHEPLACANLPRSLTDSCINYSYLEDTEHIDGTNNFVHKNGMLDLSVVLKAVYLVLNHDISSRICDVALNIVECLLQLGVVPCVEKNRKKSENKENETL 707
BLAST of Protein unc-80 vs. Ensembl Human
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:26582]) HSP 1 Score: 741.495 bits (1913), Expect = 0.000e+0 Identity = 447/1313 (34.04%), Postives = 719/1313 (54.76%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF--QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESP--------YRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
E +D +L Y+ V +L+ +++ K A +L E+++ DI P AWELLL D + +AA + +L A+K+P ++ E H + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + +C + + + ++++ K+F + +R Q+ E + K + EE++++ R+ +T I ++A +E + + E ++E N A RRLS + + + RN S+R GS+ +S + V ED+++ + T QP Q VFP+ +CAA +PI+HL++DG+V DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P+ +H+ L ++L + PSFPR A+++EFSL+ GK+L+G+D L K W +L+ +F MPS FPW +I LFLN+FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VYS N L++AI F C QFYILHR PF+LQ+F S++ ++F N + ++D+L+++ + D L+IL+L+ KPLK+LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T + E A LA S++ L+ + + LTR P D+ N++ + + V Q++ LLEEG+ + DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + + + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1550 EGKKDSGMLKYIRLQVMSLSPAPLSLLIKAAPILTEEMYGDIQPAAWELLLSMDEHMAGAAAAMFLLCAVKVPEAVSDMLMSEFHHPETVQRLNAVLKFHTLWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPVLGMPSVPMFDPPW-VPQCSGSVQDPINEDQS-KSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPITQEACYEPTCTPNSEPEEE----------VEEVTNLASRRLSVS-PSCTSSTSHRNYSFRRGSV-WSVRSAVSAEDEEHTTEHTPNHHVPQP---PQAVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELMYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPESQSTHYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMHPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPTAHKQSHVSMLQEDLLRLPSFPRSAIDAEFSLFSDPQAGKELFGLDTLQKSLWIQLLEEMFLGMPSEFPWGDEIMLFLNVFNGALILHPEDSALLRQYAATVINTAVHFNHLFSLSGYQWILPTMLQVYSDYESNPQLRQAIEFACHQFYILHRKPFVLQLFASVAPLLEFPDAANNGPSKGVSAQCLFDLLQSLEGETTDILDILELVKAEKPLKSLDFCYGNEDLTFSISEAIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQVETVPAAREEIAATAALATSLQALLYSVEVLTRPMTAPQMSRCDQGHKGTTTANHTMS-SGVNTRYQEQGAKLHFIRENLHLLEEGQ----GIPREELDERIAREEFR-----RPRESLLNICTEFYKHCGPRLKILQNLAGEPRVIALELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWTAEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVLLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRREGLAESTSQAA 2794 HSP 2 Score: 144.436 bits (363), Expect = 3.876e-33 Identity = 82/235 (34.89%), Postives = 131/235 (55.74%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDR---------------------ENKCSDGIS----------------YLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C +N+R EN+ S G + + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ ++QP ++ FTA VK
Sbjct: 4 RKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDC-NNERFGGTDRGSSWGGSSSAFIHQVENQGSPGQPCQSSSNDEEENNRRKIFQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEHRQPGVSGFTALVK 234 HSP 3 Score: 142.895 bits (359), Expect = 1.202e-32 Identity = 88/207 (42.51%), Postives = 124/207 (59.90%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRT 4845
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W +A+G RL E + + + I DE R L+ DEEE+FLDDSTVNP CP+ALK QLLL ITT+LRET LP+ RT
Sbjct: 1170 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNITKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDAIGVRLNELCHGESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSTVNPSKCGCPFALKMAACQLLLEITTFLRETFSCLPRPRT 1368 HSP 4 Score: 99.7525 bits (247), Expect = 1.333e-19 Identity = 67/205 (32.68%), Postives = 105/205 (51.22%), Query Frame = 1
Query: 2980 EELNSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQT-----HECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGR 3579
E+ S +SN+ +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ ++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+
Sbjct: 776 EKDESTPVSNHRLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRHQVFRENAQNCLTKLYKLDKMQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNKAGFG--NNFTTVDNKSTA----QNVEGIIVSAMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLAPGK 965 HSP 5 Score: 73.559 bits (179), Expect = 1.047e-11 Identity = 35/114 (30.70%), Postives = 56/114 (49.12%), Query Frame = 1
Query: 5422 KESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
K+S S T ++ ++ SP S G+S +N+ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y + R+ +SVA
Sbjct: 1407 KDSLHSSSHTLKSDAGVEEKKEGSPWSASEPSIEPEGMSNAGAEENYHRNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLYGDSVDSLRESSNISSVA 1520 HSP 6 Score: 70.4774 bits (171), Expect = 1.057e-10 Identity = 45/160 (28.12%), Postives = 75/160 (46.88%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW FLDFIV R PIF+ L PF++ K+ PA E E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2794 AYLALKVILVCFERQLGSQWYWLSLQVKEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKL-----------------LAQPA-----ENHEELSARQHIADQLERRFIPRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2931 HSP 7 Score: 63.929 bits (154), Expect = 9.762e-9 Identity = 35/119 (29.41%), Postives = 71/119 (59.66%), Query Frame = 1
Query: 2302 FFDDSPKQEKLSNEQQL-QRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFE--KRIKKKKPDQENSSM 2649
FF++ KL N+ + + EP+ L RS +D+ INY +E+ E + G+ +++ NG ++ +V+LKA++ ++N S RIC+ ++ + CL +G+ ++ +KK ++EN ++
Sbjct: 591 FFNE--HMRKLCNQVPIPEMPHEPLACANLPRSLTDSCINYSYLEDTEHIDGTNNFVHKNGMLDLSVVLKAVYLVLNHDISSRICDVALNIVECLLQLGVVPCVEKNRKKSENKENETL 707
BLAST of Protein unc-80 vs. Ensembl Human
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:26582]) HSP 1 Score: 741.495 bits (1913), Expect = 0.000e+0 Identity = 447/1313 (34.04%), Postives = 719/1313 (54.76%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF--QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESP--------YRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
E +D +L Y+ V +L+ +++ K A +L E+++ DI P AWELLL D + +AA + +L A+K+P ++ E H + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + +C + + + ++++ K+F + +R Q+ E + K + EE++++ R+ +T I ++A +E + + E ++E N A RRLS + + + RN S+R GS+ +S + V ED+++ + T QP Q VFP+ +CAA +PI+HL++DG+V DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P+ +H+ L ++L + PSFPR A+++EFSL+ GK+L+G+D L K W +L+ +F MPS FPW +I LFLN+FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VYS N L++AI F C QFYILHR PF+LQ+F S++ ++F N + ++D+L+++ + D L+IL+L+ KPLK+LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T + E A LA S++ L+ + + LTR P D+ N++ + + V Q++ LLEEG+ + DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + + + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1545 EGKKDSGMLKYIRLQVMSLSPAPLSLLIKAAPILTEEMYGDIQPAAWELLLSMDEHMAGAAAAMFLLCAVKVPEAVSDMLMSEFHHPETVQRLNAVLKFHTLWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPVLGMPSVPMFDPPW-VPQCSGSVQDPINEDQS-KSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPITQEACYEPTCTPNSEPEEE----------VEEVTNLASRRLSVS-PSCTSSTSHRNYSFRRGSV-WSVRSAVSAEDEEHTTEHTPNHHVPQP---PQAVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELMYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPESQSTHYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMHPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPTAHKQSHVSMLQEDLLRLPSFPRSAIDAEFSLFSDPQAGKELFGLDTLQKSLWIQLLEEMFLGMPSEFPWGDEIMLFLNVFNGALILHPEDSALLRQYAATVINTAVHFNHLFSLSGYQWILPTMLQVYSDYESNPQLRQAIEFACHQFYILHRKPFVLQLFASVAPLLEFPDAANNGPSKGVSAQCLFDLLQSLEGETTDILDILELVKAEKPLKSLDFCYGNEDLTFSISEAIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQVETVPAAREEIAATAALATSLQALLYSVEVLTRPMTAPQMSRCDQGHKGTTTANHTMS-SGVNTRYQEQGAKLHFIRENLHLLEEGQ----GIPREELDERIAREEFR-----RPRESLLNICTEFYKHCGPRLKILQNLAGEPRVIALELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWTAEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVLLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRREGLAESTSQAA 2789 HSP 2 Score: 144.436 bits (363), Expect = 4.208e-33 Identity = 82/235 (34.89%), Postives = 131/235 (55.74%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDR---------------------ENKCSDGIS----------------YLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C +N+R EN+ S G + + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ ++QP ++ FTA VK
Sbjct: 4 RKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDC-NNERFGGTDRGSSWGGSSSAFIHQVENQGSPGQPCQSSSNDEEENNRRKIFQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEHRQPGVSGFTALVK 234 HSP 3 Score: 142.895 bits (359), Expect = 1.180e-32 Identity = 88/207 (42.51%), Postives = 124/207 (59.90%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRT 4845
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W +A+G RL E + + + I DE R L+ DEEE+FLDDSTVNP CP+ALK QLLL ITT+LRET LP+ RT
Sbjct: 1165 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNITKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDAIGVRLNELCHGESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSTVNPSKCGCPFALKMAACQLLLEITTFLRETFSCLPRPRT 1363 HSP 4 Score: 105.916 bits (263), Expect = 1.792e-21 Identity = 67/200 (33.50%), Postives = 105/200 (52.50%), Query Frame = 1
Query: 2980 EELNSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGR 3579
E+ S +SN+ +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ ++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+
Sbjct: 776 EKDESTPVSNHRLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRHQAQNCLTKLYKLDKMQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNKAGFG--NNFTTVDNKSTA----QNVEGIIVSAMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLAPGK 960 HSP 5 Score: 73.559 bits (179), Expect = 1.100e-11 Identity = 35/114 (30.70%), Postives = 56/114 (49.12%), Query Frame = 1
Query: 5422 KESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
K+S S T ++ ++ SP S G+S +N+ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y + R+ +SVA
Sbjct: 1402 KDSLHSSSHTLKSDAGVEEKKEGSPWSASEPSIEPEGMSNAGAEENYHRNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLYGDSVDSLRESSNISSVA 1515 HSP 6 Score: 70.4774 bits (171), Expect = 1.030e-10 Identity = 45/160 (28.12%), Postives = 75/160 (46.88%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW FLDFIV R PIF+ L PF++ K+ PA E E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2789 AYLALKVILVCFERQLGSQWYWLSLQVKEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKL-----------------LAQPA-----ENHEELSARQHIADQLERRFIPRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2926 HSP 7 Score: 63.929 bits (154), Expect = 9.434e-9 Identity = 35/119 (29.41%), Postives = 71/119 (59.66%), Query Frame = 1
Query: 2302 FFDDSPKQEKLSNEQQL-QRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFE--KRIKKKKPDQENSSM 2649
FF++ KL N+ + + EP+ L RS +D+ INY +E+ E + G+ +++ NG ++ +V+LKA++ ++N S RIC+ ++ + CL +G+ ++ +KK ++EN ++
Sbjct: 591 FFNE--HMRKLCNQVPIPEMPHEPLACANLPRSLTDSCINYSYLEDTEHIDGTNNFVHKNGMLDLSVVLKAVYLVLNHDISSRICDVALNIVECLLQLGVVPCVEKNRKKSENKENETL 707
BLAST of Protein unc-80 vs. Ensembl Human
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:26582]) HSP 1 Score: 741.495 bits (1913), Expect = 0.000e+0 Identity = 447/1313 (34.04%), Postives = 719/1313 (54.76%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF--QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESP--------YRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
E +D +L Y+ V +L+ +++ K A +L E+++ DI P AWELLL D + +AA + +L A+K+P ++ E H + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + +C + + + ++++ K+F + +R Q+ E + K + EE++++ R+ +T I ++A +E + + E ++E N A RRLS + + + RN S+R GS+ +S + V ED+++ + T QP Q VFP+ +CAA +PI+HL++DG+V DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P+ +H+ L ++L + PSFPR A+++EFSL+ GK+L+G+D L K W +L+ +F MPS FPW +I LFLN+FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VYS N L++AI F C QFYILHR PF+LQ+F S++ ++F N + ++D+L+++ + D L+IL+L+ KPLK+LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T + E A LA S++ L+ + + LTR P D+ N++ + + V Q++ LLEEG+ + DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + + + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1548 EGKKDSGMLKYIRLQVMSLSPAPLSLLIKAAPILTEEMYGDIQPAAWELLLSMDEHMAGAAAAMFLLCAVKVPEAVSDMLMSEFHHPETVQRLNAVLKFHTLWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPVLGMPSVPMFDPPW-VPQCSGSVQDPINEDQS-KSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPITQEACYEPTCTPNSEPEEE----------VEEVTNLASRRLSVS-PSCTSSTSHRNYSFRRGSV-WSVRSAVSAEDEEHTTEHTPNHHVPQP---PQAVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELMYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPESQSTHYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMHPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPTAHKQSHVSMLQEDLLRLPSFPRSAIDAEFSLFSDPQAGKELFGLDTLQKSLWIQLLEEMFLGMPSEFPWGDEIMLFLNVFNGALILHPEDSALLRQYAATVINTAVHFNHLFSLSGYQWILPTMLQVYSDYESNPQLRQAIEFACHQFYILHRKPFVLQLFASVAPLLEFPDAANNGPSKGVSAQCLFDLLQSLEGETTDILDILELVKAEKPLKSLDFCYGNEDLTFSISEAIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQVETVPAAREEIAATAALATSLQALLYSVEVLTRPMTAPQMSRCDQGHKGTTTANHTMS-SGVNTRYQEQGAKLHFIRENLHLLEEGQ----GIPREELDERIAREEFR-----RPRESLLNICTEFYKHCGPRLKILQNLAGEPRVIALELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWTAEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVLLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRREGLAESTSQAA 2792 HSP 2 Score: 144.436 bits (363), Expect = 3.876e-33 Identity = 82/235 (34.89%), Postives = 131/235 (55.74%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDR---------------------ENKCSDGIS----------------YLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C +N+R EN+ S G + + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ ++QP ++ FTA VK
Sbjct: 4 RKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDC-NNERFGGTDRGSSWGGSSSAFIHQVENQGSPGQPCQSSSNDEEENNRRKIFQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEHRQPGVSGFTALVK 234 HSP 3 Score: 142.895 bits (359), Expect = 1.134e-32 Identity = 88/207 (42.51%), Postives = 124/207 (59.90%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRT 4845
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W +A+G RL E + + + I DE R L+ DEEE+FLDDSTVNP CP+ALK QLLL ITT+LRET LP+ RT
Sbjct: 1168 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNITKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDAIGVRLNELCHGESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSTVNPSKCGCPFALKMAACQLLLEITTFLRETFSCLPRPRT 1366 HSP 4 Score: 99.7525 bits (247), Expect = 1.311e-19 Identity = 67/205 (32.68%), Postives = 105/205 (51.22%), Query Frame = 1
Query: 2980 EELNSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQT-----HECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGR 3579
E+ S +SN+ +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ ++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+
Sbjct: 776 EKDESTPVSNHRLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRHQVFRENAQNCLTKLYKLDKMQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNKAGFG--NNFTTVDNKSTA----QNVEGIIVSAMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLAPGK 965 HSP 5 Score: 73.559 bits (179), Expect = 1.047e-11 Identity = 35/114 (30.70%), Postives = 56/114 (49.12%), Query Frame = 1
Query: 5422 KESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
K+S S T ++ ++ SP S G+S +N+ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y + R+ +SVA
Sbjct: 1405 KDSLHSSSHTLKSDAGVEEKKEGSPWSASEPSIEPEGMSNAGAEENYHRNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLYGDSVDSLRESSNISSVA 1518 HSP 6 Score: 70.4774 bits (171), Expect = 1.040e-10 Identity = 45/160 (28.12%), Postives = 75/160 (46.88%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW FLDFIV R PIF+ L PF++ K+ PA E E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2792 AYLALKVILVCFERQLGSQWYWLSLQVKEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKL-----------------LAQPA-----ENHEELSARQHIADQLERRFIPRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2929 HSP 7 Score: 63.929 bits (154), Expect = 9.761e-9 Identity = 35/119 (29.41%), Postives = 71/119 (59.66%), Query Frame = 1
Query: 2302 FFDDSPKQEKLSNEQQL-QRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFE--KRIKKKKPDQENSSM 2649
FF++ KL N+ + + EP+ L RS +D+ INY +E+ E + G+ +++ NG ++ +V+LKA++ ++N S RIC+ ++ + CL +G+ ++ +KK ++EN ++
Sbjct: 591 FFNE--HMRKLCNQVPIPEMPHEPLACANLPRSLTDSCINYSYLEDTEHIDGTNNFVHKNGMLDLSVVLKAVYLVLNHDISSRICDVALNIVECLLQLGVVPCVEKNRKKSENKENETL 707
BLAST of Protein unc-80 vs. Ensembl Human
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:26582]) HSP 1 Score: 155.992 bits (393), Expect = 1.623e-38 Identity = 137/554 (24.73%), Postives = 242/554 (43.68%), Query Frame = 1
Query: 9079 PHEAILQVSCDFYTSCHNRL----NEMGEKHK-ALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
P E++L + +FY C RL N GE ALELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + + + +++ L LP +I T S F+ ++ A+ G K + + +S + ++LALKV ++C+ R Q +S + ++ +K GG+ LW FLDFIV R PIF+ L PF++ K+ + + N+ + S +++ A Q++ ++F+ P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 18 PRESLLNICTEFYKHCGPRLKILQNLAGEPRVIALELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWTAEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVL------------LPPRII----------------STSRSKNFMLESSPAHCST-----------PGDAGKDLRREGLAESTS---------------------QAAYLALKVILVCFERQLGSQWYWLSLQVKEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKLLAQPAE----NHEELSARQHIADQLE--------------RRFI----PRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 457
BLAST of Protein unc-80 vs. Ensembl Celegans
Match: unc-80 (pep chromosome:WBcel235:V:20879854:20898906:1 gene:WBGene00006812.1 transcript:F25C8.3c.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-80) HSP 1 Score: 519.235 bits (1336), Expect = 2.641e-147 Identity = 292/832 (35.10%), Postives = 483/832 (58.05%), Query Frame = 1
Query: 7093 LQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHII-----YDILRAIS--TDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVL-EAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVG--DEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMG------EKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLD 9540
+ AQ +FPS+L + II LLDD V+++GV+V +A+ V+W C+VED +LFLR+ LE+LT ++ L+ LRKL+ R LP+Q+AH+L N L G++M YVR + ++I ALS+ W + P + +YFKDLKQ L+KEQ D LM+TAN+P AK+ V D + +D +F +IL ++L+ NI E D + + L D ++ +I + YVRD+YFF R+ P+L L K++PE ++ AF+ KF+E GKV+ +++ILK++P + ++FLHDE T PSFPRK+LE+ F +Y G G+QL M+ +HK W +++S +FE+M ++F + +D+HLF+N+ NG++I+H ED +LR C A I S HF +F+ G+ IMPT+LR YS+ N V + F+C+QFY LHR PF+LQM G+I+N ID +SN ++I P + +++++ + TD ED L+IL L+ KPLKALD CY ++ +++ L +A+ C+ V ++P+S R+ M++I+QA+LP +++ L + + + N+ + K E +AV +K LI +C+ L R + F V E+ V + ED++ PY L E +++T V+ E + P + +LQ+ + RL E+ E K ++LD K ++L E+A +++K+ P D++ LQ++ I P DW ES +S AL ++ RL+++++KI K R+ W ++++ I + + +A + +R + + ++++ D
Sbjct: 1906 MPVAQPLFPSALLSVVPQIIELLDDPQVDNNGVSVGDVAKKVIWTCIVEDPSLFLRHFLEKLTNRDRQEALMSQLRKLVLRFHPLPSQAAHSLLNYLFGFVMHYVRAQCEGSEKAIGMALSICWLLSPNIHGLYFKDLKQTLKKEQCDQALMITANVPSAKKIIVHGLDSTSGGIPSQFPVHEDTQFHQILNDSLEFFNIDEDDLNCFYLTDTKTGVIHLPAAYVRDYYFFHRSFYPQLTLVKLSPEVAEKKMKETAFHQKFIECGKVLLTHNILKYSPQHVIAQRVFFLHDEFTHLPSFPRKSLETCFGMY-FGPGGEQLKAMESMHKFVWAKMMSDMFEKMENAFMF-ADLHLFINVINGIMIMHCEDVLILRRCAATYISISIHFNTLFASQGFFLIMPTLLRCYSQRQTNKVFCGVVEFICRQFYTLHRKPFLLQMCGAIANIID---NSSNDFEINPMRVKAKYWFNLIKKMEEITD-EDPLDILGLVPYEKPLKALDLCYRDDPNTFCALTDAMASCICVCAFSPESKRSHHMLLIMQAMLPHMMKRLEEETLQ---SGNSPAAVKHEISQWITMAVEMKALINSCEQLVRGPTRAFDLVNSVSERGKSFVADSPQFFDPPTTNEDENSRPYHLKE----KRSTAVAWEAAEVEEQQKE---TYRRPRDTLLQLIAAYIEMASVRLKELTKLGANLEHAKIPDVLDHKCYVKLGEVALALLKVAPYDLSTTTCHGLQKYFQIILPVTDWSIESNRS--ALNIILRRLDKTLSKIAKRQSFRKRAIWIALSSWINGICDTLNAFPYIAHLHPLRTITQLCLRMMVGD 2719 HSP 2 Score: 177.948 bits (450), Expect = 1.037e-43 Identity = 145/533 (27.20%), Postives = 243/533 (45.59%), Query Frame = 1
Query: 4243 FIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPK-GDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAF----SLHSSNNSLDQ---TDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFS---TSPVEV-----------STGYCSSIGISKCSELDNFSSHM----PWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
+ID + G F+F+L++ PG P+ L+A+++ L+SPVLARA LLLE AN V+RCN+G+WP W+R ++ A+ G + +++ +QRQAG+ F+ W +G + S + E+ + + LQ+ D E+F DD VN + G+ CP AL+ + + LL IT +LRET + +P+S+ +P S D H+R I T + Q G V I +IN+ IH RRISF+ S S +++D+ D+ GS + R ++ A + + Q S H + S + + R+ G+ L KR GS T T S R ++ + ++S + + ++K SPVE + + + K S +D+ HM PW++V+ +F+N + CNHV C C++R RQC R++ ++ T+Y + + + D++N +A
Sbjct: 1080 YIDAKGIFDGARRFAFLLETARPGTFPDAPLIAAIMHLKSPVLARASLLLECANLVSRCNRGQWPEWIRSSHHRTFSLGGALANRG----TPSATRRMHSLQRQAGRYFYQWGVQIG-------------EHISKLLELSENKSKKTLQMEDTIEDFFDDGIVNNQNGEKCPIALQFIAVLLLQEITAFLRETFKTIPRSKN---SKPQTGNS-GWDKLLSHRR-WSILSNTFNAQQTGS----------------VNSITEINSSIHLNDKERRISFSATEEDSPRGSKDAIDEINAVDKKGSIHMQVVRPPSLSARLFSRQ-STHEESGGSAQGSTKSTTYVPET--GRRIATGRQRLLKR---GSPMATGTQPSLESSHKRKSFRNRKQSKQAHLEEEEKSDGAGATHILSARESLKPTDDGLQSPVESVHPVIIPHSNHGSAHSQQPVVLK-SSMDDEEQHMLSNLPWIKVLIKFSNSFDLECNHVGVCSAKCFQRVHRQCFRMIESLSTLYGMERNVSTRADKRNLLA 1567 HSP 3 Score: 164.851 bits (416), Expect = 1.054e-39 Identity = 83/216 (38.43%), Postives = 136/216 (62.96%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFFLNK--NTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN----DRENKCSDGISYLHDLSAIQLFVYLFAPLVDQI-DESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVA--SNSRATDGIGVKSAQIYIGK 732
+PL IQ+FL QTN F +K + +C++ ERV+VQNI+HGLSP++ +A+ VSRW+ ++ A PHV+ C L+ E K+P ++ KI+Y LHW+++D+++EC +N D + C L ++S+IQLF+YL APL D I +E + ++LE+GL +W + ++QPD+ CF+APVK + + + +R + + + IY+GK
Sbjct: 26 VPLPIQTFLWRQTNPFLGDKIGKLHEASCVTFERVVVQNILHGLSPSLSNALASVSRWKLVRAALPHVIQCCGSLLLANVG-EKKLP--TSLQKILYILHWMLIDSSSECIENASTKDDRSVCQSRTQGLFNISSIQLFIYLIAPLADVISEEEVVDNIRLESGLKVWQAIWQFRQPDVWCFSAPVKQRRDELPQITFARRQNPAQLDTQGIYLGK 238 HSP 4 Score: 155.992 bits (393), Expect = 5.402e-37 Identity = 85/236 (36.02%), Postives = 133/236 (56.36%), Query Frame = 1
Query: 6193 EDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAA--KTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQ 6894
++ P+L YL + V L H+ + V K LLL+ + ++ V W++L+ DP +VASAA++ I+A++K + +I L +D R S + RF +LW RF W ++ED A K+PPP I+F LPSP +G V DP W EE+ LK+ E A +T +T + TRRKQ+QEM+++AV E+R+ RQ F L + +I+ A++E A +++ D Q
Sbjct: 1665 KNKPMLTYLRSLVLQLVHSPISSVLKCCLLLSVEQHKQMIEVCWKMLIHEDPHVVASAASMFIVASVKKSEESLLIIKTALDSQDPQVRTSGIQRFYTLWRNRFHAWLKMEDGAQASFKVPPPGIDFTLPSPAIGQSQLPVVDPPWMPHLKTKIEELSLKEEEHATSQTIMTMTRTRRKQKQEMVKRAVREAEERQSEQRQLFRLRSSAIVSLAAYEPALFHHQQEQTEESDNSHQ 1900 HSP 5 Score: 57.3806 bits (137), Expect = 3.542e-7 Identity = 25/79 (31.65%), Postives = 43/79 (54.43%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQE 1503
D +AS+LD+AV+R L W E GVYW L Y+H RL+EI + + + +R N+ + + ++++ W +
Sbjct: 513 DPTIASYLDVAVIRALLITHWQEKGVYWALSYIHNRLIEIKAYMIIRKSTRQR-SNSLPSGERKLSVAPEQLTNPVWDD 590 HSP 6 Score: 54.6842 bits (130), Expect = 1.941e-6 Identity = 44/168 (26.19%), Postives = 73/168 (43.45%), Query Frame = 1
Query: 3052 LGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASL---KPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGM 3546
LGC H C K P G + R + L L ++ KF++ L + +++ LH+ T FC + + A + +Y+N FN+ G EG I + L+ ++ +L EN L D+R L+ + +E HG+ FRRV L+ +
Sbjct: 760 LGC--PHGCNEGVKS----PHG---DFLRAKAKAILAGLERVQPDKFKNILNDYVDNYGTQQVIDLLHSITSFCRSELTALDGRRASESRVPSYRNTFNEKDKG-----IEGRIINATYKTLITKISVISAELSLPENMSLQQDVRLLVNFVQEHHGNPFRRVGLSAL 913
BLAST of Protein unc-80 vs. Ensembl Celegans
Match: unc-80 (pep chromosome:WBcel235:V:20879875:20898906:1 gene:WBGene00006812.1 transcript:F25C8.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-80) HSP 1 Score: 519.235 bits (1336), Expect = 2.641e-147 Identity = 292/832 (35.10%), Postives = 483/832 (58.05%), Query Frame = 1
Query: 7093 LQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHII-----YDILRAIS--TDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVL-EAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVG--DEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMG------EKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLD 9540
+ AQ +FPS+L + II LLDD V+++GV+V +A+ V+W C+VED +LFLR+ LE+LT ++ L+ LRKL+ R LP+Q+AH+L N L G++M YVR + ++I ALS+ W + P + +YFKDLKQ L+KEQ D LM+TAN+P AK+ V D + +D +F +IL ++L+ NI E D + + L D ++ +I + YVRD+YFF R+ P+L L K++PE ++ AF+ KF+E GKV+ +++ILK++P + ++FLHDE T PSFPRK+LE+ F +Y G G+QL M+ +HK W +++S +FE+M ++F + +D+HLF+N+ NG++I+H ED +LR C A I S HF +F+ G+ IMPT+LR YS+ N V + F+C+QFY LHR PF+LQM G+I+N ID +SN ++I P + +++++ + TD ED L+IL L+ KPLKALD CY ++ +++ L +A+ C+ V ++P+S R+ M++I+QA+LP +++ L + + + N+ + K E +AV +K LI +C+ L R + F V E+ V + ED++ PY L E +++T V+ E + P + +LQ+ + RL E+ E K ++LD K ++L E+A +++K+ P D++ LQ++ I P DW ES +S AL ++ RL+++++KI K R+ W ++++ I + + +A + +R + + ++++ D
Sbjct: 1906 MPVAQPLFPSALLSVVPQIIELLDDPQVDNNGVSVGDVAKKVIWTCIVEDPSLFLRHFLEKLTNRDRQEALMSQLRKLVLRFHPLPSQAAHSLLNYLFGFVMHYVRAQCEGSEKAIGMALSICWLLSPNIHGLYFKDLKQTLKKEQCDQALMITANVPSAKKIIVHGLDSTSGGIPSQFPVHEDTQFHQILNDSLEFFNIDEDDLNCFYLTDTKTGVIHLPAAYVRDYYFFHRSFYPQLTLVKLSPEVAEKKMKETAFHQKFIECGKVLLTHNILKYSPQHVIAQRVFFLHDEFTHLPSFPRKSLETCFGMY-FGPGGEQLKAMESMHKFVWAKMMSDMFEKMENAFMF-ADLHLFINVINGIMIMHCEDVLILRRCAATYISISIHFNTLFASQGFFLIMPTLLRCYSQRQTNKVFCGVVEFICRQFYTLHRKPFLLQMCGAIANIID---NSSNDFEINPMRVKAKYWFNLIKKMEEITD-EDPLDILGLVPYEKPLKALDLCYRDDPNTFCALTDAMASCICVCAFSPESKRSHHMLLIMQAMLPHMMKRLEEETLQ---SGNSPAAVKHEISQWITMAVEMKALINSCEQLVRGPTRAFDLVNSVSERGKSFVADSPQFFDPPTTNEDENSRPYHLKE----KRSTAVAWEAAEVEEQQKE---TYRRPRDTLLQLIAAYIEMASVRLKELTKLGANLEHAKIPDVLDHKCYVKLGEVALALLKVAPYDLSTTTCHGLQKYFQIILPVTDWSIESNRS--ALNIILRRLDKTLSKIAKRQSFRKRAIWIALSSWINGICDTLNAFPYIAHLHPLRTITQLCLRMMVGD 2719 HSP 2 Score: 177.948 bits (450), Expect = 1.037e-43 Identity = 145/533 (27.20%), Postives = 243/533 (45.59%), Query Frame = 1
Query: 4243 FIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPK-GDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAF----SLHSSNNSLDQ---TDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFS---TSPVEV-----------STGYCSSIGISKCSELDNFSSHM----PWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
+ID + G F+F+L++ PG P+ L+A+++ L+SPVLARA LLLE AN V+RCN+G+WP W+R ++ A+ G + +++ +QRQAG+ F+ W +G + S + E+ + + LQ+ D E+F DD VN + G+ CP AL+ + + LL IT +LRET + +P+S+ +P S D H+R I T + Q G V I +IN+ IH RRISF+ S S +++D+ D+ GS + R ++ A + + Q S H + S + + R+ G+ L KR GS T T S R ++ + ++S + + ++K SPVE + + + K S +D+ HM PW++V+ +F+N + CNHV C C++R RQC R++ ++ T+Y + + + D++N +A
Sbjct: 1080 YIDAKGIFDGARRFAFLLETARPGTFPDAPLIAAIMHLKSPVLARASLLLECANLVSRCNRGQWPEWIRSSHHRTFSLGGALANRG----TPSATRRMHSLQRQAGRYFYQWGVQIG-------------EHISKLLELSENKSKKTLQMEDTIEDFFDDGIVNNQNGEKCPIALQFIAVLLLQEITAFLRETFKTIPRSKN---SKPQTGNS-GWDKLLSHRR-WSILSNTFNAQQTGS----------------VNSITEINSSIHLNDKERRISFSATEEDSPRGSKDAIDEINAVDKKGSIHMQVVRPPSLSARLFSRQ-STHEESGGSAQGSTKSTTYVPET--GRRIATGRQRLLKR---GSPMATGTQPSLESSHKRKSFRNRKQSKQAHLEEEEKSDGAGATHILSARESLKPTDDGLQSPVESVHPVIIPHSNHGSAHSQQPVVLK-SSMDDEEQHMLSNLPWIKVLIKFSNSFDLECNHVGVCSAKCFQRVHRQCFRMIESLSTLYGMERNVSTRADKRNLLA 1567 HSP 3 Score: 164.851 bits (416), Expect = 1.054e-39 Identity = 83/216 (38.43%), Postives = 136/216 (62.96%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFFLNK--NTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN----DRENKCSDGISYLHDLSAIQLFVYLFAPLVDQI-DESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVA--SNSRATDGIGVKSAQIYIGK 732
+PL IQ+FL QTN F +K + +C++ ERV+VQNI+HGLSP++ +A+ VSRW+ ++ A PHV+ C L+ E K+P ++ KI+Y LHW+++D+++EC +N D + C L ++S+IQLF+YL APL D I +E + ++LE+GL +W + ++QPD+ CF+APVK + + + +R + + + IY+GK
Sbjct: 26 VPLPIQTFLWRQTNPFLGDKIGKLHEASCVTFERVVVQNILHGLSPSLSNALASVSRWKLVRAALPHVIQCCGSLLLANVG-EKKLP--TSLQKILYILHWMLIDSSSECIENASTKDDRSVCQSRTQGLFNISSIQLFIYLIAPLADVISEEEVVDNIRLESGLKVWQAIWQFRQPDVWCFSAPVKQRRDELPQITFARRQNPAQLDTQGIYLGK 238 HSP 4 Score: 155.992 bits (393), Expect = 5.402e-37 Identity = 85/236 (36.02%), Postives = 133/236 (56.36%), Query Frame = 1
Query: 6193 EDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAA--KTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQ 6894
++ P+L YL + V L H+ + V K LLL+ + ++ V W++L+ DP +VASAA++ I+A++K + +I L +D R S + RF +LW RF W ++ED A K+PPP I+F LPSP +G V DP W EE+ LK+ E A +T +T + TRRKQ+QEM+++AV E+R+ RQ F L + +I+ A++E A +++ D Q
Sbjct: 1665 KNKPMLTYLRSLVLQLVHSPISSVLKCCLLLSVEQHKQMIEVCWKMLIHEDPHVVASAASMFIVASVKKSEESLLIIKTALDSQDPQVRTSGIQRFYTLWRNRFHAWLKMEDGAQASFKVPPPGIDFTLPSPAIGQSQLPVVDPPWMPHLKTKIEELSLKEEEHATSQTIMTMTRTRRKQKQEMVKRAVREAEERQSEQRQLFRLRSSAIVSLAAYEPALFHHQQEQTEESDNSHQ 1900 HSP 5 Score: 57.3806 bits (137), Expect = 3.542e-7 Identity = 25/79 (31.65%), Postives = 43/79 (54.43%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQE 1503
D +AS+LD+AV+R L W E GVYW L Y+H RL+EI + + + +R N+ + + ++++ W +
Sbjct: 513 DPTIASYLDVAVIRALLITHWQEKGVYWALSYIHNRLIEIKAYMIIRKSTRQR-SNSLPSGERKLSVAPEQLTNPVWDD 590 HSP 6 Score: 54.6842 bits (130), Expect = 1.941e-6 Identity = 44/168 (26.19%), Postives = 73/168 (43.45%), Query Frame = 1
Query: 3052 LGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASL---KPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGM 3546
LGC H C K P G + R + L L ++ KF++ L + +++ LH+ T FC + + A + +Y+N FN+ G EG I + L+ ++ +L EN L D+R L+ + +E HG+ FRRV L+ +
Sbjct: 760 LGC--PHGCNEGVKS----PHG---DFLRAKAKAILAGLERVQPDKFKNILNDYVDNYGTQQVIDLLHSITSFCRSELTALDGRRASESRVPSYRNTFNEKDKG-----IEGRIINATYKTLITKISVISAELSLPENMSLQQDVRLLVNFVQEHHGNPFRRVGLSAL 913
BLAST of Protein unc-80 vs. Ensembl Celegans
Match: unc-80 (pep chromosome:WBcel235:V:20879854:20898906:1 gene:WBGene00006812.1 transcript:F25C8.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-80) HSP 1 Score: 519.235 bits (1336), Expect = 2.902e-147 Identity = 292/832 (35.10%), Postives = 483/832 (58.05%), Query Frame = 1
Query: 7093 LQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHII-----YDILRAIS--TDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVL-EAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVG--DEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMG------EKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLD 9540
+ AQ +FPS+L + II LLDD V+++GV+V +A+ V+W C+VED +LFLR+ LE+LT ++ L+ LRKL+ R LP+Q+AH+L N L G++M YVR + ++I ALS+ W + P + +YFKDLKQ L+KEQ D LM+TAN+P AK+ V D + +D +F +IL ++L+ NI E D + + L D ++ +I + YVRD+YFF R+ P+L L K++PE ++ AF+ KF+E GKV+ +++ILK++P + ++FLHDE T PSFPRK+LE+ F +Y G G+QL M+ +HK W +++S +FE+M ++F + +D+HLF+N+ NG++I+H ED +LR C A I S HF +F+ G+ IMPT+LR YS+ N V + F+C+QFY LHR PF+LQM G+I+N ID +SN ++I P + +++++ + TD ED L+IL L+ KPLKALD CY ++ +++ L +A+ C+ V ++P+S R+ M++I+QA+LP +++ L + + + N+ + K E +AV +K LI +C+ L R + F V E+ V + ED++ PY L E +++T V+ E + P + +LQ+ + RL E+ E K ++LD K ++L E+A +++K+ P D++ LQ++ I P DW ES +S AL ++ RL+++++KI K R+ W ++++ I + + +A + +R + + ++++ D
Sbjct: 1915 MPVAQPLFPSALLSVVPQIIELLDDPQVDNNGVSVGDVAKKVIWTCIVEDPSLFLRHFLEKLTNRDRQEALMSQLRKLVLRFHPLPSQAAHSLLNYLFGFVMHYVRAQCEGSEKAIGMALSICWLLSPNIHGLYFKDLKQTLKKEQCDQALMITANVPSAKKIIVHGLDSTSGGIPSQFPVHEDTQFHQILNDSLEFFNIDEDDLNCFYLTDTKTGVIHLPAAYVRDYYFFHRSFYPQLTLVKLSPEVAEKKMKETAFHQKFIECGKVLLTHNILKYSPQHVIAQRVFFLHDEFTHLPSFPRKSLETCFGMY-FGPGGEQLKAMESMHKFVWAKMMSDMFEKMENAFMF-ADLHLFINVINGIMIMHCEDVLILRRCAATYISISIHFNTLFASQGFFLIMPTLLRCYSQRQTNKVFCGVVEFICRQFYTLHRKPFLLQMCGAIANIID---NSSNDFEINPMRVKAKYWFNLIKKMEEITD-EDPLDILGLVPYEKPLKALDLCYRDDPNTFCALTDAMASCICVCAFSPESKRSHHMLLIMQAMLPHMMKRLEEETLQ---SGNSPAAVKHEISQWITMAVEMKALINSCEQLVRGPTRAFDLVNSVSERGKSFVADSPQFFDPPTTNEDENSRPYHLKE----KRSTAVAWEAAEVEEQQKE---TYRRPRDTLLQLIAAYIEMASVRLKELTKLGANLEHAKIPDVLDHKCYVKLGEVALALLKVAPYDLSTTTCHGLQKYFQIILPVTDWSIESNRS--ALNIILRRLDKTLSKIAKRQSFRKRAIWIALSSWINGICDTLNAFPYIAHLHPLRTITQLCLRMMVGD 2728 HSP 2 Score: 178.333 bits (451), Expect = 7.939e-44 Identity = 145/533 (27.20%), Postives = 243/533 (45.59%), Query Frame = 1
Query: 4243 FIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPK-GDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAF----SLHSSNNSLDQ---TDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFS---TSPVEV-----------STGYCSSIGISKCSELDNFSSHM----PWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
+ID + G F+F+L++ PG P+ L+A+++ L+SPVLARA LLLE AN V+RCN+G+WP W+R ++ A+ G + +++ +QRQAG+ F+ W +G + S + E+ + + LQ+ D E+F DD VN + G+ CP AL+ + + LL IT +LRET + +P+S+ +P S D H+R I T + Q G V I +IN+ IH RRISF+ S S +++D+ D+ GS + R ++ A + + Q S H + S + + R+ G+ L KR GS T T S R ++ + ++S + + ++K SPVE + + + K S +D+ HM PW++V+ +F+N + CNHV C C++R RQC R++ ++ T+Y + + + D++N +A
Sbjct: 1098 YIDAKGIFDGARRFAFLLETARPGTFPDAPLIAAIMHLKSPVLARASLLLECANLVSRCNRGQWPEWIRSSHHRTFSLGGALANRG----TPSATRRMHSLQRQAGRYFYQWGVQIG-------------EHISKLLELSENKSKKTLQMEDTIEDFFDDGIVNNQNGEKCPIALQFIAVLLLQEITAFLRETFKTIPRSKN---SKPQTGNS-GWDKLLSHRR-WSILSNTFNAQQTGS----------------VNSITEINSSIHLNDKERRISFSATEEDSPRGSKDAIDEINAVDKKGSIHMQVVRPPSLSARLFSRQ-STHEESGGSAQGSTKSTTYVPET--GRRIATGRQRLLKR---GSPMATGTQPSLESSHKRKSFRNRKQSKQAHLEEEEKSDGAGATHILSARESLKPTDDGLQSPVESVHPVIIPHSNHGSAHSQQPVVLK-SSMDDEEQHMLSNLPWIKVLIKFSNSFDLECNHVGVCSAKCFQRVHRQCFRMIESLSTLYGMERNVSTRADKRNLLA 1585 HSP 3 Score: 164.851 bits (416), Expect = 1.128e-39 Identity = 83/216 (38.43%), Postives = 136/216 (62.96%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFFLNK--NTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN----DRENKCSDGISYLHDLSAIQLFVYLFAPLVDQI-DESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVA--SNSRATDGIGVKSAQIYIGK 732
+PL IQ+FL QTN F +K + +C++ ERV+VQNI+HGLSP++ +A+ VSRW+ ++ A PHV+ C L+ E K+P ++ KI+Y LHW+++D+++EC +N D + C L ++S+IQLF+YL APL D I +E + ++LE+GL +W + ++QPD+ CF+APVK + + + +R + + + IY+GK
Sbjct: 44 VPLPIQTFLWRQTNPFLGDKIGKLHEASCVTFERVVVQNILHGLSPSLSNALASVSRWKLVRAALPHVIQCCGSLLLANVG-EKKLP--TSLQKILYILHWMLIDSSSECIENASTKDDRSVCQSRTQGLFNISSIQLFIYLIAPLADVISEEEVVDNIRLESGLKVWQAIWQFRQPDVWCFSAPVKQRRDELPQITFARRQNPAQLDTQGIYLGK 256 HSP 4 Score: 155.992 bits (393), Expect = 4.889e-37 Identity = 85/236 (36.02%), Postives = 133/236 (56.36%), Query Frame = 1
Query: 6193 EDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAA--KTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQ 6894
++ P+L YL + V L H+ + V K LLL+ + ++ V W++L+ DP +VASAA++ I+A++K + +I L +D R S + RF +LW RF W ++ED A K+PPP I+F LPSP +G V DP W EE+ LK+ E A +T +T + TRRKQ+QEM+++AV E+R+ RQ F L + +I+ A++E A +++ D Q
Sbjct: 1674 KNKPMLTYLRSLVLQLVHSPISSVLKCCLLLSVEQHKQMIEVCWKMLIHEDPHVVASAASMFIVASVKKSEESLLIIKTALDSQDPQVRTSGIQRFYTLWRNRFHAWLKMEDGAQASFKVPPPGIDFTLPSPAIGQSQLPVVDPPWMPHLKTKIEELSLKEEEHATSQTIMTMTRTRRKQKQEMVKRAVREAEERQSEQRQLFRLRSSAIVSLAAYEPALFHHQQEQTEESDNSHQ 1909 HSP 5 Score: 57.3806 bits (137), Expect = 3.633e-7 Identity = 25/79 (31.65%), Postives = 43/79 (54.43%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQE 1503
D +AS+LD+AV+R L W E GVYW L Y+H RL+EI + + + +R N+ + + ++++ W +
Sbjct: 531 DPTIASYLDVAVIRALLITHWQEKGVYWALSYIHNRLIEIKAYMIIRKSTRQR-SNSLPSGERKLSVAPEQLTNPVWDD 608 HSP 6 Score: 54.6842 bits (130), Expect = 1.925e-6 Identity = 44/168 (26.19%), Postives = 73/168 (43.45%), Query Frame = 1
Query: 3052 LGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASL---KPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGM 3546
LGC H C K P G + R + L L ++ KF++ L + +++ LH+ T FC + + A + +Y+N FN+ G EG I + L+ ++ +L EN L D+R L+ + +E HG+ FRRV L+ +
Sbjct: 778 LGC--PHGCNEGVKS----PHG---DFLRAKAKAILAGLERVQPDKFKNILNDYVDNYGTQQVIDLLHSITSFCRSELTALDGRRASESRVPSYRNTFNEKDKG-----IEGRIINATYKTLITKISVISAELSLPENMSLQQDVRLLVNFVQEHHGNPFRRVGLSAL 931
BLAST of Protein unc-80 vs. Ensembl Celegans
Match: unc-80 (pep chromosome:WBcel235:V:20879854:20898906:1 gene:WBGene00006812.1 transcript:F25C8.3e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-80) HSP 1 Score: 518.85 bits (1335), Expect = 3.627e-147 Identity = 292/829 (35.22%), Postives = 482/829 (58.14%), Query Frame = 1
Query: 7102 AQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHII-----YDILRAIS--TDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVL-EAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVG--DEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMG------EKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLD 9540
AQ +FPS+L + II LLDD V+++GV+V +A+ V+W C+VED +LFLR+ LE+LT ++ L+ LRKL+ R LP+Q+AH+L N L G++M YVR + ++I ALS+ W + P + +YFKDLKQ L+KEQ D LM+TAN+P AK+ V D + +D +F +IL ++L+ NI E D + + L D ++ +I + YVRD+YFF R+ P+L L K++PE ++ AF+ KF+E GKV+ +++ILK++P + ++FLHDE T PSFPRK+LE+ F +Y G G+QL M+ +HK W +++S +FE+M ++F + +D+HLF+N+ NG++I+H ED +LR C A I S HF +F+ G+ IMPT+LR YS+ N V + F+C+QFY LHR PF+LQM G+I+N ID +SN ++I P + +++++ + TD ED L+IL L+ KPLKALD CY ++ +++ L +A+ C+ V ++P+S R+ M++I+QA+LP +++ L + + + N+ + K E +AV +K LI +C+ L R + F V E+ V + ED++ PY L E +++T V+ E + P + +LQ+ + RL E+ E K ++LD K ++L E+A +++K+ P D++ LQ++ I P DW ES +S AL ++ RL+++++KI K R+ W ++++ I + + +A + +R + + ++++ D
Sbjct: 1874 AQPLFPSALLSVVPQIIELLDDPQVDNNGVSVGDVAKKVIWTCIVEDPSLFLRHFLEKLTNRDRQEALMSQLRKLVLRFHPLPSQAAHSLLNYLFGFVMHYVRAQCEGSEKAIGMALSICWLLSPNIHGLYFKDLKQTLKKEQCDQALMITANVPSAKKIIVHGLDSTSGGIPSQFPVHEDTQFHQILNDSLEFFNIDEDDLNCFYLTDTKTGVIHLPAAYVRDYYFFHRSFYPQLTLVKLSPEVAEKKMKETAFHQKFIECGKVLLTHNILKYSPQHVIAQRVFFLHDEFTHLPSFPRKSLETCFGMY-FGPGGEQLKAMESMHKFVWAKMMSDMFEKMENAFMF-ADLHLFINVINGIMIMHCEDVLILRRCAATYISISIHFNTLFASQGFFLIMPTLLRCYSQRQTNKVFCGVVEFICRQFYTLHRKPFLLQMCGAIANIID---NSSNDFEINPMRVKAKYWFNLIKKMEEITD-EDPLDILGLVPYEKPLKALDLCYRDDPNTFCALTDAMASCICVCAFSPESKRSHHMLLIMQAMLPHMMKRLEEETLQ---SGNSPAAVKHEISQWITMAVEMKALINSCEQLVRGPTRAFDLVNSVSERGKSFVADSPQFFDPPTTNEDENSRPYHLKE----KRSTAVAWEAAEVEEQQKE---TYRRPRDTLLQLIAAYIEMASVRLKELTKLGANLEHAKIPDVLDHKCYVKLGEVALALLKVAPYDLSTTTCHGLQKYFQIILPVTDWSIESNRS--ALNIILRRLDKTLSKIAKRQSFRKRAIWIALSSWINGICDTLNAFPYIAHLHPLRTITQLCLRMMVGD 2684 HSP 2 Score: 176.407 bits (446), Expect = 3.234e-43 Identity = 144/513 (28.07%), Postives = 234/513 (45.61%), Query Frame = 1
Query: 4243 FIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPK-GDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISF-AFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVST----FTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
+ID + G F+F+L++ PG P+ L+A+++ L+SPVLARA LLLE AN V+RCN+G+WP W+R ++ A+ G + +++ +QRQAG+ F+ W +G + S + E+ + + LQ+ D E+F DD VN + G+ CP AL+ + + LL IT +LRET + +P+S+ +P S D H+R I T + Q G V I +IN+ IH RRISF A S S D DE + +K R + + + P + T L S +RKS R R++S + + K + G+ S S++ + QS V + P S S PV + + S E + S++PW++V+ +F+N + CNHV C C++R RQC R++ ++ T+Y + + + D++N +A
Sbjct: 1098 YIDAKGIFDGARRFAFLLETARPGTFPDAPLIAAIMHLKSPVLARASLLLECANLVSRCNRGQWPEWIRSSHHRTFSLGGALANRG----TPSATRRMHSLQRQAGRYFYQWGVQIG-------------EHISKLLELSENKSKKTLQMEDTIEDFFDDGIVNNQNGEKCPIALQFIAVLLLQEITAFLRETFKTIPRSKN---SKPQTGNS-GWDKLLSHRR-WSILSNTFNAQQTGS----------------VNSITEINSSIHLNDKERRISFSATEEDSPRGSKDAIDEINAVDKKGRRIATGRQRL----LKRGSPMATGTQPSLE-------SSHKRKS------FRNRKQS----KQAHLEEEEKSDGAGATHILSARE--SLKPTDDGLQSPVESVHPVIIPHSNHGSAHSQQPVVLKS--------SMDDEEQHMLSNLPWIKVLIKFSNSFDLECNHVGVCSAKCFQRVHRQCFRMIESLSTLYGMERNVSTRADKRNLLA 1541 HSP 3 Score: 164.851 bits (416), Expect = 1.016e-39 Identity = 83/216 (38.43%), Postives = 136/216 (62.96%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFFLNK--NTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN----DRENKCSDGISYLHDLSAIQLFVYLFAPLVDQI-DESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVA--SNSRATDGIGVKSAQIYIGK 732
+PL IQ+FL QTN F +K + +C++ ERV+VQNI+HGLSP++ +A+ VSRW+ ++ A PHV+ C L+ E K+P ++ KI+Y LHW+++D+++EC +N D + C L ++S+IQLF+YL APL D I +E + ++LE+GL +W + ++QPD+ CF+APVK + + + +R + + + IY+GK
Sbjct: 44 VPLPIQTFLWRQTNPFLGDKIGKLHEASCVTFERVVVQNILHGLSPSLSNALASVSRWKLVRAALPHVIQCCGSLLLANVG-EKKLP--TSLQKILYILHWMLIDSSSECIENASTKDDRSVCQSRTQGLFNISSIQLFIYLIAPLADVISEEEVVDNIRLESGLKVWQAIWQFRQPDVWCFSAPVKQRRDELPQITFARRQNPAQLDTQGIYLGK 256 HSP 4 Score: 155.606 bits (392), Expect = 5.522e-37 Identity = 85/236 (36.02%), Postives = 133/236 (56.36%), Query Frame = 1
Query: 6193 EDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAA--KTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQ 6894
++ P+L YL + V L H+ + V K LLL+ + ++ V W++L+ DP +VASAA++ I+A++K + +I L +D R S + RF +LW RF W ++ED A K+PPP I+F LPSP +G V DP W EE+ LK+ E A +T +T + TRRKQ+QEM+++AV E+R+ RQ F L + +I+ A++E A +++ D Q
Sbjct: 1630 KNKPMLTYLRSLVLQLVHSPISSVLKCCLLLSVEQHKQMIEVCWKMLIHEDPHVVASAASMFIVASVKKSEESLLIIKTALDSQDPQVRTSGIQRFYTLWRNRFHAWLKMEDGAQASFKVPPPGIDFTLPSPAIGQSQLPVVDPPWMPHLKTKIEELSLKEEEHATSQTIMTMTRTRRKQKQEMVKRAVREAEERQSEQRQLFRLRSSAIVSLAAYEPALFHHQQEQTEESDNSHQ 1865 HSP 5 Score: 56.9954 bits (136), Expect = 3.690e-7 Identity = 25/79 (31.65%), Postives = 43/79 (54.43%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQE 1503
D +AS+LD+AV+R L W E GVYW L Y+H RL+EI + + + +R N+ + + ++++ W +
Sbjct: 531 DPTIASYLDVAVIRALLITHWQEKGVYWALSYIHNRLIEIKAYMIIRKSTRQR-SNSLPSGERKLSVAPEQLTNPVWDD 608 HSP 6 Score: 54.6842 bits (130), Expect = 2.126e-6 Identity = 44/168 (26.19%), Postives = 73/168 (43.45%), Query Frame = 1
Query: 3052 LGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASL---KPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGM 3546
LGC H C K P G + R + L L ++ KF++ L + +++ LH+ T FC + + A + +Y+N FN+ G EG I + L+ ++ +L EN L D+R L+ + +E HG+ FRRV L+ +
Sbjct: 778 LGC--PHGCNEGVKS----PHG---DFLRAKAKAILAGLERVQPDKFKNILNDYVDNYGTQQVIDLLHSITSFCRSELTALDGRRASESRVPSYRNTFNEKDKG-----IEGRIINATYKTLITKISVISAELSLPENMSLQQDVRLLVNFVQEHHGNPFRRVGLSAL 931
BLAST of Protein unc-80 vs. Ensembl Celegans
Match: unc-80 (pep chromosome:WBcel235:V:20879854:20898906:1 gene:WBGene00006812.1 transcript:F25C8.3a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-80) HSP 1 Score: 510.76 bits (1314), Expect = 1.078e-144 Identity = 292/844 (34.60%), Postives = 483/844 (57.23%), Query Frame = 1
Query: 7093 LQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEK------------DELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHII-----YDILRAIS--TDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVL-EAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVG--DEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMG------EKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLD 9540
+ AQ +FPS+L + II LLDD V+++GV+V +A+ V+W C+VED +LFLR+ LE+LT + + L+ LRKL+ R LP+Q+AH+L N L G++M YVR + ++I ALS+ W + P + +YFKDLKQ L+KEQ D LM+TAN+P AK+ V D + +D +F +IL ++L+ NI E D + + L D ++ +I + YVRD+YFF R+ P+L L K++PE ++ AF+ KF+E GKV+ +++ILK++P + ++FLHDE T PSFPRK+LE+ F +Y G G+QL M+ +HK W +++S +FE+M ++F + +D+HLF+N+ NG++I+H ED +LR C A I S HF +F+ G+ IMPT+LR YS+ N V + F+C+QFY LHR PF+LQM G+I+N ID +SN ++I P + +++++ + TD ED L+IL L+ KPLKALD CY ++ +++ L +A+ C+ V ++P+S R+ M++I+QA+LP +++ L + + + N+ + K E +AV +K LI +C+ L R + F V E+ V + ED++ PY L E +++T V+ E + P + +LQ+ + RL E+ E K ++LD K ++L E+A +++K+ P D++ LQ++ I P DW ES +S AL ++ RL+++++KI K R+ W ++++ I + + +A + +R + + ++++ D
Sbjct: 1924 MPVAQPLFPSALLSVVPQIIELLDDPQVDNNGVSVGDVAKKVIWTCIVEDPSLFLRHFLEKLTNRDRQVLISEYAPTPAYEALMSQLRKLVLRFHPLPSQAAHSLLNYLFGFVMHYVRAQCEGSEKAIGMALSICWLLSPNIHGLYFKDLKQTLKKEQCDQALMITANVPSAKKIIVHGLDSTSGGIPSQFPVHEDTQFHQILNDSLEFFNIDEDDLNCFYLTDTKTGVIHLPAAYVRDYYFFHRSFYPQLTLVKLSPEVAEKKMKETAFHQKFIECGKVLLTHNILKYSPQHVIAQRVFFLHDEFTHLPSFPRKSLETCFGMY-FGPGGEQLKAMESMHKFVWAKMMSDMFEKMENAFMF-ADLHLFINVINGIMIMHCEDVLILRRCAATYISISIHFNTLFASQGFFLIMPTLLRCYSQRQTNKVFCGVVEFICRQFYTLHRKPFLLQMCGAIANIID---NSSNDFEINPMRVKAKYWFNLIKKMEEITD-EDPLDILGLVPYEKPLKALDLCYRDDPNTFCALTDAMASCICVCAFSPESKRSHHMLLIMQAMLPHMMKRLEEETLQ---SGNSPAAVKHEISQWITMAVEMKALINSCEQLVRGPTRAFDLVNSVSERGKSFVADSPQFFDPPTTNEDENSRPYHLKE----KRSTAVAWEAAEVEEQQKE---TYRRPRDTLLQLIAAYIEMASVRLKELTKLGANLEHAKIPDVLDHKCYVKLGEVALALLKVAPYDLSTTTCHGLQKYFQIILPVTDWSIESNRS--ALNIILRRLDKTLSKIAKRQSFRKRAIWIALSSWINGICDTLNAFPYIAHLHPLRTITQLCLRMMVGD 2749 HSP 2 Score: 178.333 bits (451), Expect = 8.581e-44 Identity = 145/533 (27.20%), Postives = 244/533 (45.78%), Query Frame = 1
Query: 4243 FIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPK-GDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAF----SLHSSNNSLDQ---TDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVK---EFSTSPVEV-----------STGYCSSIGISKCSELDNFSSHM----PWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
+ID + G F+F+L++ PG P+ L+A+++ L+SPVLARA LLLE AN V+RCN+G+WP W+R ++ A+ G + +++ +QRQAG+ F+ W +G + S + E+ + + LQ+ D E+F DD VN + G+ CP AL+ + + LL IT +LRET + +P+S+ +P S D H+R I T + Q G V I +IN+ IH RRISF+ S S +++D+ D+ GS + R ++ A + + Q S H + S + + R+ G+ L KR GS T T S R ++ + ++S + + ++K + SPVE + + + K S +D+ HM PW++V+ +F+N + CNHV C C++R RQC R++ ++ T+Y + + + D++N +A
Sbjct: 1098 YIDAKGIFDGARRFAFLLETARPGTFPDAPLIAAIMHLKSPVLARASLLLECANLVSRCNRGQWPEWIRSSHHRTFSLGGALANRG----TPSATRRMHSLQRQAGRYFYQWGVQIG-------------EHISKLLELSENKSKKTLQMEDTIEDFFDDGIVNNQNGEKCPIALQFIAVLLLQEITAFLRETFKTIPRSKN---SKPQTGNS-GWDKLLSHRR-WSILSNTFNAQQTGS----------------VNSITEINSSIHLNDKERRISFSATEEDSPRGSKDAIDEINAVDKKGSIHMQVVRPPSLSARLFSRQ-STHEESGGSAQGSTKSTTYVPET--GRRIATGRQRLLKR---GSPMATGTQPSLESSHKRKSFRNRKQSKQAHLEEEEKSDGAGATHILSARESLKPTDDGLQSPVESVHPVIIPHSNHGSAHSQQPVVLK-SSMDDEEQHMLSNLPWIKVLIKFSNSFDLECNHVGVCSAKCFQRVHRQCFRMIESLSTLYGMERNVSTRADKRNLLA 1585 HSP 3 Score: 164.851 bits (416), Expect = 1.121e-39 Identity = 83/216 (38.43%), Postives = 136/216 (62.96%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFFLNK--NTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN----DRENKCSDGISYLHDLSAIQLFVYLFAPLVDQI-DESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVA--SNSRATDGIGVKSAQIYIGK 732
+PL IQ+FL QTN F +K + +C++ ERV+VQNI+HGLSP++ +A+ VSRW+ ++ A PHV+ C L+ E K+P ++ KI+Y LHW+++D+++EC +N D + C L ++S+IQLF+YL APL D I +E + ++LE+GL +W + ++QPD+ CF+APVK + + + +R + + + IY+GK
Sbjct: 44 VPLPIQTFLWRQTNPFLGDKIGKLHEASCVTFERVVVQNILHGLSPSLSNALASVSRWKLVRAALPHVIQCCGSLLLANVG-EKKLP--TSLQKILYILHWMLIDSSSECIENASTKDDRSVCQSRTQGLFNISSIQLFIYLIAPLADVISEEEVVDNIRLESGLKVWQAIWQFRQPDVWCFSAPVKQRRDELPQITFARRQNPAQLDTQGIYLGK 256 HSP 4 Score: 155.992 bits (393), Expect = 4.356e-37 Identity = 85/236 (36.02%), Postives = 133/236 (56.36%), Query Frame = 1
Query: 6193 EDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAA--KTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQ 6894
++ P+L YL + V L H+ + V K LLL+ + ++ V W++L+ DP +VASAA++ I+A++K + +I L +D R S + RF +LW RF W ++ED A K+PPP I+F LPSP +G V DP W EE+ LK+ E A +T +T + TRRKQ+QEM+++AV E+R+ RQ F L + +I+ A++E A +++ D Q
Sbjct: 1683 KNKPMLTYLRSLVLQLVHSPISSVLKCCLLLSVEQHKQMIEVCWKMLIHEDPHVVASAASMFIVASVKKSEESLLIIKTALDSQDPQVRTSGIQRFYTLWRNRFHAWLKMEDGAQASFKVPPPGIDFTLPSPAIGQSQLPVVDPPWMPHLKTKIEELSLKEEEHATSQTIMTMTRTRRKQKQEMVKRAVREAEERQSEQRQLFRLRSSAIVSLAAYEPALFHHQQEQTEESDNSHQ 1918 HSP 5 Score: 57.3806 bits (137), Expect = 3.634e-7 Identity = 25/79 (31.65%), Postives = 43/79 (54.43%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQE 1503
D +AS+LD+AV+R L W E GVYW L Y+H RL+EI + + + +R N+ + + ++++ W +
Sbjct: 531 DPTIASYLDVAVIRALLITHWQEKGVYWALSYIHNRLIEIKAYMIIRKSTRQR-SNSLPSGERKLSVAPEQLTNPVWDD 608 HSP 6 Score: 54.6842 bits (130), Expect = 1.878e-6 Identity = 44/168 (26.19%), Postives = 73/168 (43.45%), Query Frame = 1
Query: 3052 LGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASL---KPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGM 3546
LGC H C K P G + R + L L ++ KF++ L + +++ LH+ T FC + + A + +Y+N FN+ G EG I + L+ ++ +L EN L D+R L+ + +E HG+ FRRV L+ +
Sbjct: 778 LGC--PHGCNEGVKS----PHG---DFLRAKAKAILAGLERVQPDKFKNILNDYVDNYGTQQVIDLLHSITSFCRSELTALDGRRASESRVPSYRNTFNEKDKG-----IEGRIINATYKTLITKISVISAELSLPENMSLQQDVRLLVNFVQEHHGNPFRRVGLSAL 931
BLAST of Protein unc-80 vs. Ensembl Fly
Match: unc80 (gene:FBgn0039536 transcript:FBtr0330108) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 487/1503 (32.40%), Postives = 766/1503 (50.96%), Query Frame = 1
Query: 5980 RSRRK--ESMFGNHSPHRRKDSVPLFDKFLKSRTXXXXXXXXXSSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSA-STQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVF---DEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQ--GENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQN-SVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKH----KALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXX-XXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVS 10446
RS RK E SP +RKDS+ D+ SD+ L + EK A + K K+ E+ PIL ++ ++ NL H + KGA++L E++ + MP AWELLLE + + S+A V ++ ++K A ++ R L+H+D + R+ A+ R+ LW CRF W R+E++A K+PP IEF LPSP +G V DP W + +V L Q+ ++ VTA+ +R+ QQ E + A+ + +++ R F +T + S++ E G+E +L I E+D +G+ ++S L +A +FPS LC++ + I+ LDD + SDG AV IA V+W CLVE++ LFLRY+ ERLTR +D++ +LR LI+ +P LP Q+A AL+N+++GYIMFYVR+ + E + ALS+LW +V V I FKDLKQILRKEQ D ++++TAN+P AK+ V D+D + +Q++T F ++LKEAL I E++ Y L D +S+ I N + Y+RD YFFKR+ P++RL M PE+ LQ+ KF+EIGKV +++ILK+ + + FLH+EL K PSFPRKALE + L+ G GK L G+D+LHK W RL++ +FE M +F +++DI LFLN+ +G ILHAED+ ++R +A I A+ +FK IFS NGY IMPT+L+VYS + N ++ I + KQFY+L+R PFILQMFGS+S +D G +K++ ++++L ++ D LNI +L+ KPLKA+DFCY +E+D +VL+ +TLCV V+ Y+ +S R QM+IIL+AILP L+ QI P +S R I I QLAV+++ ++ C+ L + + P+ + K S + N S+ S L+ ++E+ + + + R KN + S E R P + +L V DF T RL E+ +K K E+LD K +RL+++A S++K+ P D + + LQR+M + P +W ++++++ AL ++ R+++ KI K RRN DW++ L+K + + R+ V + ++ L+ ++ LI+ ++ P V++ G A P F + V++ AL + S + L C + F T E + I+ L +C G G D ++ ++ F+ +L N + P A G G R TG+ G + G S +P + + LY+ +FLAL++ IC+ + I V+ DLG + + LW F++F+VT RTP+++ L+PF+ K+S
Sbjct: 1643 RSTRKVSEQSSTQTSPSKRKDSLSRKDRI---------------SDDPDL--EMAEKLAKAFRQEKE--KKMQEEPPILKFIRIHIRNLFHFPLATLLKGAVVLTEEMVIEAMPAAWELLLETNHDTATSSAAVFLMGSVKAQNFAFDIMQRALKHKDPDIRIGAIQRYLVLWKCRFHVWPRMEENAHDVTFKVPPGGIEFTLPSPKIGIESLPVVDPPWMPVQQTKDMDVTLNQDRH-RSLVTATKSRKMQQTEAIRNALRQQRDKQRAERHSFLITM----------IPISQQASHEPGME------------------KLEDHEI----------------------------EEDLDGTRMSSH------LHHAHSLFPSVLCSSVMQIVGCLDDAAIGSDGNAVYEIAYQVIWVCLVEESALFLRYVFERLTR-DRQDQMFKLLRHLIRFVPRLPQQAAFALYNSIIGYIMFYVRSSNELKQELVGSALSVLWMVVHSVHGIMFKDLKQILRKEQCDASILLTANVPAAKKIVVHGPADDDYNIPSQFPVQEDT---LFCQLLKEALDYYPIDEKNTSHYCLVDYKSSKILNPNWYIRDLYFFKRSQYPEVRLMLMRPEESFLALQKQELTKKFVEIGKVHLTWAILKNV--DMVVQRVVFLHEELMKLPSFPRKALEVDLDLHHGGEYGKVLLGLDVLHKFMWVRLIARMFEAMAGNFAYSADIQLFLNVLSGASILHAEDSCIMRYVMATFINAAFNFKNIFSTNGYFMIMPTLLQVYSLHQTNKLITTTIEYAVKQFYLLNRKPFILQMFGSVSAILDTDEDGTYGEAHKVQSSCLFNLLLSLEDPSPDPLNIAELVKEPKPLKAIDFCYHDEDDDVTVLDCITLCVMVVSYSAESTRGYQMLIILEAILPCYLQ---QIQSPSYIPLQGKSERDI----ILQLAVAIRTMVHNCEGLAKSYNGPYRNSPEHKGSSQ--RNCSRGPPCSPGLDFEEETHPKYMTDAR-TKNMMDSAEDSEMIRTEYRR------PRDVLLSVVADFLTKSTVRLAELAKKMPSDTKPTEVLDAKCHIRLADIAHSLLKVSPYDPESMACRGLQRYMQAVLPRAEWSNDTLRN--ALVTILRRIDKVFLKISKKPSIRRNTDWEAAAGLLKGIHETIIRHSYVLHWQQMKTLISTVQNLIV--------------------NEPGIPEGVSSAG-------AALMSQNPPAFFCSAVVRLVALQVVSPVDCFSLVQICGGSSE-FATQEKAEGFLMHLIMPLCLKVCSGRGVSDVGELKMSDVSFLLTAVL----------------------NAMSPPA---GRTGQAVSQINRV--------TGDLRAGSLTFTG-SRDAKRPARI------------------------SGSLYQAAFLALRIVCICFESRLSNEWPRIVRVMRDLGRRNEAAPDLWSFMEFVVTHRTPLYIVLLPFILHKIS 2953 HSP 2 Score: 216.083 bits (549), Expect = 3.582e-55 Identity = 162/506 (32.02%), Postives = 251/506 (49.60%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDL-ESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSA-IPMSGDHQFMNNTN-KKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPK-SRTISLKEPI-YETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESI-VGEIGQINTEIHPAPGNRRISFAF------SLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K+RK + ++ GM SF+L++ PG P+PQLVA++LDL ++P++ARA LLE A+FV CNKG+WP+WM+ GSY S A I ++ Q ++ T+ ++ +QR AG+MFH WAE +GARLE L E+ N S + D K REL DEEE+FLD+++VNP G+ CP++LK + LL IT +LR+T+ LPK S+ I +P +E Y + + + + + TS S++SI G G +E R+ISF S +SSN +L + G +AR+ P TSA+ F+ T ++T GS +RR L+ RR + + T S ++ S+ R ++S+ + + ES + P + +E D+ + +MPW++ + + N+ C H +CHP CY+R R C RL+ A + VY
Sbjct: 1179 KERKLVPTEPVRVGMLRLSFLLETCAPGSFPDPQLVAAVLDLPQAPLVARATFLLECAHFVHLCNKGQWPAWMKQNV-GSYRASGANINLNQMKQQVSQTSARRTHILQRAAGKMFHQWAEMVGARLEEILFTERLQYEAVNAS-LTDPEKQRELLQQDEEEDFLDETSVNPHGNDCPHSLKLIACVLLFEITAFLRDTYLMLPKTSKLIHRDKPAPWEKVYREANRRWSMALSSMGHSQTS---------------AQSLQSIAAGNDGAGQSE-------RKISFVLHEPDNESENSSNTTLTK---EGEEARR-PTTSAVRPFL------LRRGTATTTG----------GSFKRRS-------LKLRRNTKDSKDIET-----------DFNMQSRRKVSSLSDRSDTSEQGMISGGEESPGILSDDQQPESP----------TDSNENDDTAKNMPWLKAIIDLMSSYNYYCTHKGYCHPFCYKRHMRSCTRLVKATRKVY 1612 HSP 3 Score: 143.28 bits (360), Expect = 3.865e-33 Identity = 78/213 (36.62%), Postives = 114/213 (53.52%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFF------LNKNT------------RDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMH-CASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDND----------RENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCR 663
+P+ +Q+FL Q F L+++T AC S E+VLVQNI GLSP + + ++ RW+ ++ A PHVMH CA+LL ++ P ETK++Y++ WI++ AA EC D++ E K YL + I LFVYLFAP++ + ES FQ +LENG+ +W + + + P CFTAPVK K R
Sbjct: 53 LPVSVQTFLWRQIAPFIRPKLGKLHESTCLFCQHAPGHHESKEACKSFEKVLVQNIQFGLSPPLTKGLGVIPRWRLLQGALPHVMHACAALLYNRVKDMQAIGP---VETKLLYTMQWILLYAAEECADDEGGEDLGLGDAAEPKSKSIDQYLFSVPTITLFVYLFAPIIHHLKESDFQNFRLENGIKLWQGMWDNRAPGAPCFTAPVKPKAR 262 HSP 4 Score: 97.8265 bits (242), Expect = 2.140e-19 Identity = 79/277 (28.52%), Postives = 130/277 (46.93%), Query Frame = 1
Query: 2998 GMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVW-RKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDL---HNRTSSLSAALVATELLQQMAANNQNYKPGKKNI--FKRYSSAV 3810
G ++I+M I + +++LGC H C + + G + R Q + L ++ + ++ + F+ M + L +++++ HA+ FC DP+SL S+ Y F+ ++G +E + +PLV R V + KDL EN LY DIRQL+ Y K HG FR V L+G+L V R K+G + + I + S D+ RS L TSS A+L+ TE A ++YK + + F+R ++ V
Sbjct: 792 GEHAHEISMSITRRALQVLGC--PHGCNDGVR-------GPPADFLRNQCQKILSRMLRQAGQRTKRFMQEMVKTSPLPELIDYFHAFLAFCVDPSSL--LSPLSQGGYSTNFSGGMSGG----AEAQVVGAVFKPLVSRFVEASKDLKGPENIALYGDIRQLVTYVKGAHGGPFRLVALSGILAVTPRPHKKGPSAQTTRVIRHIPQANANQSLQNDD----NRSQRRLLLKKRSTSSACASLLETE------ACEEHYKTSQSPLSNFRRRTTGV 1043 HSP 5 Score: 57.3806 bits (137), Expect = 3.624e-7 Identity = 48/169 (28.40%), Postives = 74/169 (43.79%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLXXXXXXXXXXXXXXXXTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSS 1773
D A+ LD+AVLRCLF W E G++W L+YL+ RL +I E ++ Q + KRS S + EI S +Q P G DS + + + DP ++A + + K++KM D + F + F K+E + D +S
Sbjct: 425 DVSAATFLDVAVLRCLFISHWQEEGIFWSLQYLYNRLSDIGEEAAITLNQPR-------KRSNSLPIPQIEI--SLYQGP--GSNSRDSPGSSVVKDY----IEIPDPSPTVTACVAEEPQSAPSTTERRGSEKKKRVKMADLRA-FVETKMFSKSEKNLEKVGLDTNS 577
BLAST of Protein unc-80 vs. Ensembl Fly
Match: unc80 (gene:FBgn0039536 transcript:FBtr0330111) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 487/1503 (32.40%), Postives = 766/1503 (50.96%), Query Frame = 1
Query: 5980 RSRRK--ESMFGNHSPHRRKDSVPLFDKFLKSRTXXXXXXXXXSSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSA-STQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVF---DEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQ--GENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQN-SVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKH----KALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXX-XXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVS 10446
RS RK E SP +RKDS+ D+ SD+ L + EK A + K K+ E+ PIL ++ ++ NL H + KGA++L E++ + MP AWELLLE + + S+A V ++ ++K A ++ R L+H+D + R+ A+ R+ LW CRF W R+E++A K+PP IEF LPSP +G V DP W + +V L Q+ ++ VTA+ +R+ QQ E + A+ + +++ R F +T + S++ E G+E +L I E+D +G+ ++S L +A +FPS LC++ + I+ LDD + SDG AV IA V+W CLVE++ LFLRY+ ERLTR +D++ +LR LI+ +P LP Q+A AL+N+++GYIMFYVR+ + E + ALS+LW +V V I FKDLKQILRKEQ D ++++TAN+P AK+ V D+D + +Q++T F ++LKEAL I E++ Y L D +S+ I N + Y+RD YFFKR+ P++RL M PE+ LQ+ KF+EIGKV +++ILK+ + + FLH+EL K PSFPRKALE + L+ G GK L G+D+LHK W RL++ +FE M +F +++DI LFLN+ +G ILHAED+ ++R +A I A+ +FK IFS NGY IMPT+L+VYS + N ++ I + KQFY+L+R PFILQMFGS+S +D G +K++ ++++L ++ D LNI +L+ KPLKA+DFCY +E+D +VL+ +TLCV V+ Y+ +S R QM+IIL+AILP L+ QI P +S R I I QLAV+++ ++ C+ L + + P+ + K S + N S+ S L+ ++E+ + + + R KN + S E R P + +L V DF T RL E+ +K K E+LD K +RL+++A S++K+ P D + + LQR+M + P +W ++++++ AL ++ R+++ KI K RRN DW++ L+K + + R+ V + ++ L+ ++ LI+ ++ P V++ G A P F + V++ AL + S + L C + F T E + I+ L +C G G D ++ ++ F+ +L N + P A G G R TG+ G + G S +P + + LY+ +FLAL++ IC+ + I V+ DLG + + LW F++F+VT RTP+++ L+PF+ K+S
Sbjct: 1669 RSTRKVSEQSSTQTSPSKRKDSLSRKDRI---------------SDDPDL--EMAEKLAKAFRQEKE--KKMQEEPPILKFIRIHIRNLFHFPLATLLKGAVVLTEEMVIEAMPAAWELLLETNHDTATSSAAVFLMGSVKAQNFAFDIMQRALKHKDPDIRIGAIQRYLVLWKCRFHVWPRMEENAHDVTFKVPPGGIEFTLPSPKIGIESLPVVDPPWMPVQQTKDMDVTLNQDRH-RSLVTATKSRKMQQTEAIRNALRQQRDKQRAERHSFLITM----------IPISQQASHEPGME------------------KLEDHEI----------------------------EEDLDGTRMSSH------LHHAHSLFPSVLCSSVMQIVGCLDDAAIGSDGNAVYEIAYQVIWVCLVEESALFLRYVFERLTR-DRQDQMFKLLRHLIRFVPRLPQQAAFALYNSIIGYIMFYVRSSNELKQELVGSALSVLWMVVHSVHGIMFKDLKQILRKEQCDASILLTANVPAAKKIVVHGPADDDYNIPSQFPVQEDT---LFCQLLKEALDYYPIDEKNTSHYCLVDYKSSKILNPNWYIRDLYFFKRSQYPEVRLMLMRPEESFLALQKQELTKKFVEIGKVHLTWAILKNV--DMVVQRVVFLHEELMKLPSFPRKALEVDLDLHHGGEYGKVLLGLDVLHKFMWVRLIARMFEAMAGNFAYSADIQLFLNVLSGASILHAEDSCIMRYVMATFINAAFNFKNIFSTNGYFMIMPTLLQVYSLHQTNKLITTTIEYAVKQFYLLNRKPFILQMFGSVSAILDTDEDGTYGEAHKVQSSCLFNLLLSLEDPSPDPLNIAELVKEPKPLKAIDFCYHDEDDDVTVLDCITLCVMVVSYSAESTRGYQMLIILEAILPCYLQ---QIQSPSYIPLQGKSERDI----ILQLAVAIRTMVHNCEGLAKSYNGPYRNSPEHKGSSQ--RNCSRGPPCSPGLDFEEETHPKYMTDAR-TKNMMDSAEDSEMIRTEYRR------PRDVLLSVVADFLTKSTVRLAELAKKMPSDTKPTEVLDAKCHIRLADIAHSLLKVSPYDPESMACRGLQRYMQAVLPRAEWSNDTLRN--ALVTILRRIDKVFLKISKKPSIRRNTDWEAAAGLLKGIHETIIRHSYVLHWQQMKTLISTVQNLIV--------------------NEPGIPEGVSSAG-------AALMSQNPPAFFCSAVVRLVALQVVSPVDCFSLVQICGGSSE-FATQEKAEGFLMHLIMPLCLKVCSGRGVSDVGELKMSDVSFLLTAVL----------------------NAMSPPA---GRTGQAVSQINRV--------TGDLRAGSLTFTG-SRDAKRPARI------------------------SGSLYQAAFLALRIVCICFESRLSNEWPRIVRVMRDLGRRNEAAPDLWSFMEFVVTHRTPLYIVLLPFILHKIS 2979 HSP 2 Score: 216.083 bits (549), Expect = 3.718e-55 Identity = 162/506 (32.02%), Postives = 251/506 (49.60%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDL-ESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSA-IPMSGDHQFMNNTN-KKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPK-SRTISLKEPI-YETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESI-VGEIGQINTEIHPAPGNRRISFAF------SLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K+RK + ++ GM SF+L++ PG P+PQLVA++LDL ++P++ARA LLE A+FV CNKG+WP+WM+ GSY S A I ++ Q ++ T+ ++ +QR AG+MFH WAE +GARLE L E+ N S + D K REL DEEE+FLD+++VNP G+ CP++LK + LL IT +LR+T+ LPK S+ I +P +E Y + + + + + TS S++SI G G +E R+ISF S +SSN +L + G +AR+ P TSA+ F+ T ++T GS +RR L+ RR + + T S ++ S+ R ++S+ + + ES + P + +E D+ + +MPW++ + + N+ C H +CHP CY+R R C RL+ A + VY
Sbjct: 1205 KERKLVPTEPVRVGMLRLSFLLETCAPGSFPDPQLVAAVLDLPQAPLVARATFLLECAHFVHLCNKGQWPAWMKQNV-GSYRASGANINLNQMKQQVSQTSARRTHILQRAAGKMFHQWAEMVGARLEEILFTERLQYEAVNAS-LTDPEKQRELLQQDEEEDFLDETSVNPHGNDCPHSLKLIACVLLFEITAFLRDTYLMLPKTSKLIHRDKPAPWEKVYREANRRWSMALSSMGHSQTS---------------AQSLQSIAAGNDGAGQSE-------RKISFVLHEPDNESENSSNTTLTK---EGEEARR-PTTSAVRPFL------LRRGTATTTG----------GSFKRRS-------LKLRRNTKDSKDIET-----------DFNMQSRRKVSSLSDRSDTSEQGMISGGEESPGILSDDQQPESP----------TDSNENDDTAKNMPWLKAIIDLMSSYNYYCTHKGYCHPFCYKRHMRSCTRLVKATRKVY 1638 HSP 3 Score: 143.665 bits (361), Expect = 3.532e-33 Identity = 78/213 (36.62%), Postives = 114/213 (53.52%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFF------LNKNT------------RDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMH-CASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDND----------RENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCR 663
+P+ +Q+FL Q F L+++T AC S E+VLVQNI GLSP + + ++ RW+ ++ A PHVMH CA+LL ++ P ETK++Y++ WI++ AA EC D++ E K YL + I LFVYLFAP++ + ES FQ +LENG+ +W + + + P CFTAPVK K R
Sbjct: 53 LPVSVQTFLWRQIAPFIRPKLGKLHESTCLFCQHAPGHHESKEACKSFEKVLVQNIQFGLSPPLTKGLGVIPRWRLLQGALPHVMHACAALLYNRVKDMQAIGP---VETKLLYTMQWILLYAAEECADDEGGEDLGLGDAAEPKSKSIDQYLFSVPTITLFVYLFAPIIHHLKESDFQNFRLENGIKLWQGMWDNRAPGAPCFTAPVKPKAR 262 HSP 4 Score: 95.9005 bits (237), Expect = 9.933e-19 Identity = 76/287 (26.48%), Postives = 133/287 (46.34%), Query Frame = 1
Query: 2998 GMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASL-KPAGINSRNNYKNC------------FNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVW-RKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNI--FKRYSSAV 3810
G ++I+M I + +++LGC H C + + G + R Q + L ++ + ++ + F+ M + L +++++ HA+ FC DP+SL P ++ +KN ++ + +G + +E + +PLV R V + KDL EN LY DIRQL+ Y K HG FR V L+G+L V R K+G + + I + S D+ RS L + S S+A + L + A ++YK + + F+R ++ V
Sbjct: 798 GEHAHEISMSITRRALQVLGC--PHGCNDGVR-------GPPADFLRNQCQKILSRMLRQAGQRTKRFMQEMVKTSPLPELIDYFHAFLAFCVDPSSLLSPLTHKRQSGFKNANTDIGGVPGQGGYSTNFSGGMSGGAEAQVVGAVFKPLVSRFVEASKDLKGPENIALYGDIRQLVTYVKGAHGGPFRLVALSGILAVTPRPHKKGPSAQTTRVIRHIPQANANQSLQNDD----NRSQRRLLLKKRSTSSACAVS--LLETEACEEHYKTSQSPLSNFRRRTTGV 1069 HSP 5 Score: 57.7658 bits (138), Expect = 3.335e-7 Identity = 48/169 (28.40%), Postives = 74/169 (43.79%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLXXXXXXXXXXXXXXXXTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSS 1773
D A+ LD+AVLRCLF W E G++W L+YL+ RL +I E ++ Q + KRS S + EI S +Q P G DS + + + DP ++A + + K++KM D + F + F K+E + D +S
Sbjct: 425 DVSAATFLDVAVLRCLFISHWQEEGIFWSLQYLYNRLSDIGEEAAITLNQPR-------KRSNSLPIPQIEI--SLYQGP--GSNSRDSPGSSVVKDY----IEIPDPSPTVTACVAEEPQSAPSTTERRGSEKKKRVKMADLRA-FVETKMFSKSEKNLEKVGLDTNS 577
BLAST of Protein unc-80 vs. Ensembl Fly
Match: unc80 (gene:FBgn0039536 transcript:FBtr0330109) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 487/1503 (32.40%), Postives = 766/1503 (50.96%), Query Frame = 1
Query: 5980 RSRRK--ESMFGNHSPHRRKDSVPLFDKFLKSRTXXXXXXXXXSSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSA-STQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVF---DEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQ--GENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQN-SVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKH----KALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXX-XXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVS 10446
RS RK E SP +RKDS+ D+ SD+ L + EK A + K K+ E+ PIL ++ ++ NL H + KGA++L E++ + MP AWELLLE + + S+A V ++ ++K A ++ R L+H+D + R+ A+ R+ LW CRF W R+E++A K+PP IEF LPSP +G V DP W + +V L Q+ ++ VTA+ +R+ QQ E + A+ + +++ R F +T + S++ E G+E +L I E+D +G+ ++S L +A +FPS LC++ + I+ LDD + SDG AV IA V+W CLVE++ LFLRY+ ERLTR +D++ +LR LI+ +P LP Q+A AL+N+++GYIMFYVR+ + E + ALS+LW +V V I FKDLKQILRKEQ D ++++TAN+P AK+ V D+D + +Q++T F ++LKEAL I E++ Y L D +S+ I N + Y+RD YFFKR+ P++RL M PE+ LQ+ KF+EIGKV +++ILK+ + + FLH+EL K PSFPRKALE + L+ G GK L G+D+LHK W RL++ +FE M +F +++DI LFLN+ +G ILHAED+ ++R +A I A+ +FK IFS NGY IMPT+L+VYS + N ++ I + KQFY+L+R PFILQMFGS+S +D G +K++ ++++L ++ D LNI +L+ KPLKA+DFCY +E+D +VL+ +TLCV V+ Y+ +S R QM+IIL+AILP L+ QI P +S R I I QLAV+++ ++ C+ L + + P+ + K S + N S+ S L+ ++E+ + + + R KN + S E R P + +L V DF T RL E+ +K K E+LD K +RL+++A S++K+ P D + + LQR+M + P +W ++++++ AL ++ R+++ KI K RRN DW++ L+K + + R+ V + ++ L+ ++ LI+ ++ P V++ G A P F + V++ AL + S + L C + F T E + I+ L +C G G D ++ ++ F+ +L N + P A G G R TG+ G + G S +P + + LY+ +FLAL++ IC+ + I V+ DLG + + LW F++F+VT RTP+++ L+PF+ K+S
Sbjct: 1643 RSTRKVSEQSSTQTSPSKRKDSLSRKDRI---------------SDDPDL--EMAEKLAKAFRQEKE--KKMQEEPPILKFIRIHIRNLFHFPLATLLKGAVVLTEEMVIEAMPAAWELLLETNHDTATSSAAVFLMGSVKAQNFAFDIMQRALKHKDPDIRIGAIQRYLVLWKCRFHVWPRMEENAHDVTFKVPPGGIEFTLPSPKIGIESLPVVDPPWMPVQQTKDMDVTLNQDRH-RSLVTATKSRKMQQTEAIRNALRQQRDKQRAERHSFLITM----------IPISQQASHEPGME------------------KLEDHEI----------------------------EEDLDGTRMSSH------LHHAHSLFPSVLCSSVMQIVGCLDDAAIGSDGNAVYEIAYQVIWVCLVEESALFLRYVFERLTR-DRQDQMFKLLRHLIRFVPRLPQQAAFALYNSIIGYIMFYVRSSNELKQELVGSALSVLWMVVHSVHGIMFKDLKQILRKEQCDASILLTANVPAAKKIVVHGPADDDYNIPSQFPVQEDT---LFCQLLKEALDYYPIDEKNTSHYCLVDYKSSKILNPNWYIRDLYFFKRSQYPEVRLMLMRPEESFLALQKQELTKKFVEIGKVHLTWAILKNV--DMVVQRVVFLHEELMKLPSFPRKALEVDLDLHHGGEYGKVLLGLDVLHKFMWVRLIARMFEAMAGNFAYSADIQLFLNVLSGASILHAEDSCIMRYVMATFINAAFNFKNIFSTNGYFMIMPTLLQVYSLHQTNKLITTTIEYAVKQFYLLNRKPFILQMFGSVSAILDTDEDGTYGEAHKVQSSCLFNLLLSLEDPSPDPLNIAELVKEPKPLKAIDFCYHDEDDDVTVLDCITLCVMVVSYSAESTRGYQMLIILEAILPCYLQ---QIQSPSYIPLQGKSERDI----ILQLAVAIRTMVHNCEGLAKSYNGPYRNSPEHKGSSQ--RNCSRGPPCSPGLDFEEETHPKYMTDAR-TKNMMDSAEDSEMIRTEYRR------PRDVLLSVVADFLTKSTVRLAELAKKMPSDTKPTEVLDAKCHIRLADIAHSLLKVSPYDPESMACRGLQRYMQAVLPRAEWSNDTLRN--ALVTILRRIDKVFLKISKKPSIRRNTDWEAAAGLLKGIHETIIRHSYVLHWQQMKTLISTVQNLIV--------------------NEPGIPEGVSSAG-------AALMSQNPPAFFCSAVVRLVALQVVSPVDCFSLVQICGGSSE-FATQEKAEGFLMHLIMPLCLKVCSGRGVSDVGELKMSDVSFLLTAVL----------------------NAMSPPA---GRTGQAVSQINRV--------TGDLRAGSLTFTG-SRDAKRPARI------------------------SGSLYQAAFLALRIVCICFESRLSNEWPRIVRVMRDLGRRNEAAPDLWSFMEFVVTHRTPLYIVLLPFILHKIS 2953 HSP 2 Score: 216.468 bits (550), Expect = 3.426e-55 Identity = 162/506 (32.02%), Postives = 251/506 (49.60%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDL-ESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSA-IPMSGDHQFMNNTN-KKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPK-SRTISLKEPI-YETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESI-VGEIGQINTEIHPAPGNRRISFAF------SLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K+RK + ++ GM SF+L++ PG P+PQLVA++LDL ++P++ARA LLE A+FV CNKG+WP+WM+ GSY S A I ++ Q ++ T+ ++ +QR AG+MFH WAE +GARLE L E+ N S + D K REL DEEE+FLD+++VNP G+ CP++LK + LL IT +LR+T+ LPK S+ I +P +E Y + + + + + TS S++SI G G +E R+ISF S +SSN +L + G +AR+ P TSA+ F+ T ++T GS +RR L+ RR + + T S ++ S+ R ++S+ + + ES + P + +E D+ + +MPW++ + + N+ C H +CHP CY+R R C RL+ A + VY
Sbjct: 1179 KERKLVPTEPVRVGMLRLSFLLETCAPGSFPDPQLVAAVLDLPQAPLVARATFLLECAHFVHLCNKGQWPAWMKQNV-GSYRASGANINLNQMKQQVSQTSARRTHILQRAAGKMFHQWAEMVGARLEEILFTERLQYEAVNAS-LTDPEKQRELLQQDEEEDFLDETSVNPHGNDCPHSLKLIACVLLFEITAFLRDTYLMLPKTSKLIHRDKPAPWEKVYREANRRWSMALSSMGHSQTS---------------AQSLQSIAAGNDGAGQSE-------RKISFVLHEPDNESENSSNTTLTK---EGEEARR-PTTSAVRPFL------LRRGTATTTG----------GSFKRRS-------LKLRRNTKDSKDIET-----------DFNMQSRRKVSSLSDRSDTSEQGMISGGEESPGILSDDQQPESP----------TDSNENDDTAKNMPWLKAIIDLMSSYNYYCTHKGYCHPFCYKRHMRSCTRLVKATRKVY 1612 HSP 3 Score: 143.665 bits (361), Expect = 3.549e-33 Identity = 78/213 (36.62%), Postives = 114/213 (53.52%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFF------LNKNT------------RDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMH-CASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDND----------RENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCR 663
+P+ +Q+FL Q F L+++T AC S E+VLVQNI GLSP + + ++ RW+ ++ A PHVMH CA+LL ++ P ETK++Y++ WI++ AA EC D++ E K YL + I LFVYLFAP++ + ES FQ +LENG+ +W + + + P CFTAPVK K R
Sbjct: 53 LPVSVQTFLWRQIAPFIRPKLGKLHESTCLFCQHAPGHHESKEACKSFEKVLVQNIQFGLSPPLTKGLGVIPRWRLLQGALPHVMHACAALLYNRVKDMQAIGP---VETKLLYTMQWILLYAAEECADDEGGEDLGLGDAAEPKSKSIDQYLFSVPTITLFVYLFAPIIHHLKESDFQNFRLENGIKLWQGMWDNRAPGAPCFTAPVKPKAR 262 HSP 4 Score: 95.9005 bits (237), Expect = 9.830e-19 Identity = 76/287 (26.48%), Postives = 133/287 (46.34%), Query Frame = 1
Query: 2998 GMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASL-KPAGINSRNNYKNC------------FNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVW-RKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNI--FKRYSSAV 3810
G ++I+M I + +++LGC H C + + G + R Q + L ++ + ++ + F+ M + L +++++ HA+ FC DP+SL P ++ +KN ++ + +G + +E + +PLV R V + KDL EN LY DIRQL+ Y K HG FR V L+G+L V R K+G + + I + S D+ RS L + S S+A + L + A ++YK + + F+R ++ V
Sbjct: 772 GEHAHEISMSITRRALQVLGC--PHGCNDGVR-------GPPADFLRNQCQKILSRMLRQAGQRTKRFMQEMVKTSPLPELIDYFHAFLAFCVDPSSLLSPLTHKRQSGFKNANTDIGGVPGQGGYSTNFSGGMSGGAEAQVVGAVFKPLVSRFVEASKDLKGPENIALYGDIRQLVTYVKGAHGGPFRLVALSGILAVTPRPHKKGPSAQTTRVIRHIPQANANQSLQNDD----NRSQRRLLLKKRSTSSACAVS--LLETEACEEHYKTSQSPLSNFRRRTTGV 1043 HSP 5 Score: 56.9954 bits (136), Expect = 5.553e-7 Identity = 32/80 (40.00%), Postives = 44/80 (55.00%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEP 1506
D A+ LD+AVLRCLF W E G++W L+YL+ RL +I E ++ Q + KRS S + EI S +Q P
Sbjct: 425 DVSAATFLDVAVLRCLFISHWQEEGIFWSLQYLYNRLSDIGEEAAITLNQPR-------KRSNSLPIPQIEI--SLYQGP 495
BLAST of Protein unc-80 vs. Ensembl Fly
Match: unc80 (gene:FBgn0039536 transcript:FBtr0330110) HSP 1 Score: 726.857 bits (1875), Expect = 0.000e+0 Identity = 487/1503 (32.40%), Postives = 766/1503 (50.96%), Query Frame = 1
Query: 5980 RSRRK--ESMFGNHSPHRRKDSVPLFDKFLKSRTXXXXXXXXXSSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSA-STQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVF---DEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQ--GENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQN-SVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKH----KALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXX-XXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVS 10446
RS RK E SP +RKDS+ D+ SD+ L + EK A + K K+ E+ PIL ++ ++ NL H + KGA++L E++ + MP AWELLLE + + S+A V ++ ++K A ++ R L+H+D + R+ A+ R+ LW CRF W R+E++A K+PP IEF LPSP +G V DP W + +V L Q+ ++ VTA+ +R+ QQ E + A+ + +++ R F +T + S++ E G+E +L I E+D +G+ ++S L +A +FPS LC++ + I+ LDD + SDG AV IA V+W CLVE++ LFLRY+ ERLTR +D++ +LR LI+ +P LP Q+A AL+N+++GYIMFYVR+ + E + ALS+LW +V V I FKDLKQILRKEQ D ++++TAN+P AK+ V D+D + +Q++T F ++LKEAL I E++ Y L D +S+ I N + Y+RD YFFKR+ P++RL M PE+ LQ+ KF+EIGKV +++ILK+ + + FLH+EL K PSFPRKALE + L+ G GK L G+D+LHK W RL++ +FE M +F +++DI LFLN+ +G ILHAED+ ++R +A I A+ +FK IFS NGY IMPT+L+VYS + N ++ I + KQFY+L+R PFILQMFGS+S +D G +K++ ++++L ++ D LNI +L+ KPLKA+DFCY +E+D +VL+ +TLCV V+ Y+ +S R QM+IIL+AILP L+ QI P +S R I I QLAV+++ ++ C+ L + + P+ + K S + N S+ S L+ ++E+ + + + R KN + S E R P + +L V DF T RL E+ +K K E+LD K +RL+++A S++K+ P D + + LQR+M + P +W ++++++ AL ++ R+++ KI K RRN DW++ L+K + + R+ V + ++ L+ ++ LI+ ++ P V++ G A P F + V++ AL + S + L C + F T E + I+ L +C G G D ++ ++ F+ +L N + P A G G R TG+ G + G S +P + + LY+ +FLAL++ IC+ + I V+ DLG + + LW F++F+VT RTP+++ L+PF+ K+S
Sbjct: 1646 RSTRKVSEQSSTQTSPSKRKDSLSRKDRI---------------SDDPDL--EMAEKLAKAFRQEKE--KKMQEEPPILKFIRIHIRNLFHFPLATLLKGAVVLTEEMVIEAMPAAWELLLETNHDTATSSAAVFLMGSVKAQNFAFDIMQRALKHKDPDIRIGAIQRYLVLWKCRFHVWPRMEENAHDVTFKVPPGGIEFTLPSPKIGIESLPVVDPPWMPVQQTKDMDVTLNQDRH-RSLVTATKSRKMQQTEAIRNALRQQRDKQRAERHSFLITM----------IPISQQASHEPGME------------------KLEDHEI----------------------------EEDLDGTRMSSH------LHHAHSLFPSVLCSSVMQIVGCLDDAAIGSDGNAVYEIAYQVIWVCLVEESALFLRYVFERLTR-DRQDQMFKLLRHLIRFVPRLPQQAAFALYNSIIGYIMFYVRSSNELKQELVGSALSVLWMVVHSVHGIMFKDLKQILRKEQCDASILLTANVPAAKKIVVHGPADDDYNIPSQFPVQEDT---LFCQLLKEALDYYPIDEKNTSHYCLVDYKSSKILNPNWYIRDLYFFKRSQYPEVRLMLMRPEESFLALQKQELTKKFVEIGKVHLTWAILKNV--DMVVQRVVFLHEELMKLPSFPRKALEVDLDLHHGGEYGKVLLGLDVLHKFMWVRLIARMFEAMAGNFAYSADIQLFLNVLSGASILHAEDSCIMRYVMATFINAAFNFKNIFSTNGYFMIMPTLLQVYSLHQTNKLITTTIEYAVKQFYLLNRKPFILQMFGSVSAILDTDEDGTYGEAHKVQSSCLFNLLLSLEDPSPDPLNIAELVKEPKPLKAIDFCYHDEDDDVTVLDCITLCVMVVSYSAESTRGYQMLIILEAILPCYLQ---QIQSPSYIPLQGKSERDI----ILQLAVAIRTMVHNCEGLAKSYNGPYRNSPEHKGSSQ--RNCSRGPPCSPGLDFEEETHPKYMTDAR-TKNMMDSAEDSEMIRTEYRR------PRDVLLSVVADFLTKSTVRLAELAKKMPSDTKPTEVLDAKCHIRLADIAHSLLKVSPYDPESMACRGLQRYMQAVLPRAEWSNDTLRN--ALVTILRRIDKVFLKISKKPSIRRNTDWEAAAGLLKGIHETIIRHSYVLHWQQMKTLISTVQNLIV--------------------NEPGIPEGVSSAG-------AALMSQNPPAFFCSAVVRLVALQVVSPVDCFSLVQICGGSSE-FATQEKAEGFLMHLIMPLCLKVCSGRGVSDVGELKMSDVSFLLTAVL----------------------NAMSPPA---GRTGQAVSQINRV--------TGDLRAGSLTFTG-SRDAKRPARI------------------------SGSLYQAAFLALRIVCICFESRLSNEWPRIVRVMRDLGRRNEAAPDLWSFMEFVVTHRTPLYIVLLPFILHKIS 2956 HSP 2 Score: 216.083 bits (549), Expect = 4.421e-55 Identity = 164/506 (32.41%), Postives = 252/506 (49.80%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDL-ESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSA-IPMSGDHQFMNNTN-KKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPK-SRTISLKEPI-YETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESI-VGEIGQINTEIHPAPGNRRISFAF------SLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K+RK + ++ GM SF+L++ PG P+PQLVA++LDL ++P++ARA LLE A+FV CNKG+WP+WM+ GSY S A I ++ Q ++ T+ ++ +QR AG+MFH WAE +GARLE L E+ N S + D K REL DEEE+FLD+++VNP G+ CP++LK + LL IT +LR+T+ LPK S+ I +P +E Y + + + + + TS S++SI G G +E R+ISF S +SSN +L + G +AR+ P TSA+ F+ T ++T GS +RR L+ RR + + T S ++ S+ R ++S+ + + ES + P E T +E D+ + +MPW++ + + N+ C H +CHP CY+R R C RL+ A + VY
Sbjct: 1182 KERKLVPTEPVRVGMLRLSFLLETCAPGSFPDPQLVAAVLDLPQAPLVARATFLLECAHFVHLCNKGQWPAWMKQNV-GSYRASGANINLNQMKQQVSQTSARRTHILQRAAGKMFHQWAEMVGARLEEILFTERLQYEAVNAS-LTDPEKQRELLQQDEEEDFLDETSVNPHGNDCPHSLKLIACVLLFEITAFLRDTYLMLPKTSKLIHRDKPAPWEKVYREANRRWSMALSSMGHSQTS---------------AQSLQSIAAGNDGAGQSE-------RKISFVLHEPDNESENSSNTTLTK---EGEEARR-PTTSAVRPFL------LRRGTATTTG----------GSFKRRS-------LKLRRNTKDSKDIET-----------DFNMQSRRKVSSLSDRSDTSEQGMISGGEESPGILSDDQQP-ESPT---------DSNENDDTAKNMPWLKAIIDLMSSYNYYCTHKGYCHPFCYKRHMRSCTRLVKATRKVY 1615 HSP 3 Score: 143.665 bits (361), Expect = 3.739e-33 Identity = 78/213 (36.62%), Postives = 114/213 (53.52%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFF------LNKNT------------RDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMH-CASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDND----------RENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCR 663
+P+ +Q+FL Q F L+++T AC S E+VLVQNI GLSP + + ++ RW+ ++ A PHVMH CA+LL ++ P ETK++Y++ WI++ AA EC D++ E K YL + I LFVYLFAP++ + ES FQ +LENG+ +W + + + P CFTAPVK K R
Sbjct: 53 LPVSVQTFLWRQIAPFIRPKLGKLHESTCLFCQHAPGHHESKEACKSFEKVLVQNIQFGLSPPLTKGLGVIPRWRLLQGALPHVMHACAALLYNRVKDMQAIGP---VETKLLYTMQWILLYAAEECADDEGGEDLGLGDAAEPKSKSIDQYLFSVPTITLFVYLFAPIIHHLKESDFQNFRLENGIKLWQGMWDNRAPGAPCFTAPVKPKAR 262 HSP 4 Score: 97.8265 bits (242), Expect = 2.347e-19 Identity = 80/278 (28.78%), Postives = 131/278 (47.12%), Query Frame = 1
Query: 2998 GMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASL-KPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVW-RKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDL---HNRTSSLSAALVATELLQQMAANNQNYKPGKKNI--FKRYSSAV 3810
G ++I+M I + +++LGC H C + + G + R Q + L ++ + ++ + F+ M + L +++++ HA+ FC DP+SL P S+ Y F+ ++G +E + +PLV R V + KDL EN LY DIRQL+ Y K HG FR V L+G+L V R K+G + + I + S D+ RS L TSS A+L+ TE A ++YK + + F+R ++ V
Sbjct: 795 GEHAHEISMSITRRALQVLGC--PHGCNDGVR-------GPPADFLRNQCQKILSRMLRQAGQRTKRFMQEMVKTSPLPELIDYFHAFLAFCVDPSSLLSPL---SQGGYSTNFSGGMSGG----AEAQVVGAVFKPLVSRFVEASKDLKGPENIALYGDIRQLVTYVKGAHGGPFRLVALSGILAVTPRPHKKGPSAQTTRVIRHIPQANANQSLQNDD----NRSQRRLLLKKRSTSSACASLLETE------ACEEHYKTSQSPLSNFRRRTTGV 1046 HSP 5 Score: 57.7658 bits (138), Expect = 3.446e-7 Identity = 48/169 (28.40%), Postives = 74/169 (43.79%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLXXXXXXXXXXXXXXXXTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSS 1773
D A+ LD+AVLRCLF W E G++W L+YL+ RL +I E ++ Q + KRS S + EI S +Q P G DS + + + DP ++A + + K++KM D + F + F K+E + D +S
Sbjct: 425 DVSAATFLDVAVLRCLFISHWQEEGIFWSLQYLYNRLSDIGEEAAITLNQPR-------KRSNSLPIPQIEI--SLYQGP--GSNSRDSPGSSVVKDY----IEIPDPSPTVTACVAEEPQSAPSTTERRGSEKKKRVKMADLRA-FVETKMFSKSEKNLEKVGLDTNS 577
BLAST of Protein unc-80 vs. Ensembl Fly
Match: unc80 (gene:FBgn0039536 transcript:FBtr0330112) HSP 1 Score: 726.857 bits (1875), Expect = 0.000e+0 Identity = 487/1503 (32.40%), Postives = 766/1503 (50.96%), Query Frame = 1
Query: 5980 RSRRK--ESMFGNHSPHRRKDSVPLFDKFLKSRTXXXXXXXXXSSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSA-STQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVF---DEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQ--GENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQN-SVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKH----KALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXX-XXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVS 10446
RS RK E SP +RKDS+ D+ SD+ L + EK A + K K+ E+ PIL ++ ++ NL H + KGA++L E++ + MP AWELLLE + + S+A V ++ ++K A ++ R L+H+D + R+ A+ R+ LW CRF W R+E++A K+PP IEF LPSP +G V DP W + +V L Q+ ++ VTA+ +R+ QQ E + A+ + +++ R F +T + S++ E G+E +L I E+D +G+ ++S L +A +FPS LC++ + I+ LDD + SDG AV IA V+W CLVE++ LFLRY+ ERLTR +D++ +LR LI+ +P LP Q+A AL+N+++GYIMFYVR+ + E + ALS+LW +V V I FKDLKQILRKEQ D ++++TAN+P AK+ V D+D + +Q++T F ++LKEAL I E++ Y L D +S+ I N + Y+RD YFFKR+ P++RL M PE+ LQ+ KF+EIGKV +++ILK+ + + FLH+EL K PSFPRKALE + L+ G GK L G+D+LHK W RL++ +FE M +F +++DI LFLN+ +G ILHAED+ ++R +A I A+ +FK IFS NGY IMPT+L+VYS + N ++ I + KQFY+L+R PFILQMFGS+S +D G +K++ ++++L ++ D LNI +L+ KPLKA+DFCY +E+D +VL+ +TLCV V+ Y+ +S R QM+IIL+AILP L+ QI P +S R I I QLAV+++ ++ C+ L + + P+ + K S + N S+ S L+ ++E+ + + + R KN + S E R P + +L V DF T RL E+ +K K E+LD K +RL+++A S++K+ P D + + LQR+M + P +W ++++++ AL ++ R+++ KI K RRN DW++ L+K + + R+ V + ++ L+ ++ LI+ ++ P V++ G A P F + V++ AL + S + L C + F T E + I+ L +C G G D ++ ++ F+ +L N + P A G G R TG+ G + G S +P + + LY+ +FLAL++ IC+ + I V+ DLG + + LW F++F+VT RTP+++ L+PF+ K+S
Sbjct: 1643 RSTRKVSEQSSTQTSPSKRKDSLSRKDRI---------------SDDPDL--EMAEKLAKAFRQEKE--KKMQEEPPILKFIRIHIRNLFHFPLATLLKGAVVLTEEMVIEAMPAAWELLLETNHDTATSSAAVFLMGSVKAQNFAFDIMQRALKHKDPDIRIGAIQRYLVLWKCRFHVWPRMEENAHDVTFKVPPGGIEFTLPSPKIGIESLPVVDPPWMPVQQTKDMDVTLNQDRH-RSLVTATKSRKMQQTEAIRNALRQQRDKQRAERHSFLITM----------IPISQQASHEPGME------------------KLEDHEI----------------------------EEDLDGTRMSSH------LHHAHSLFPSVLCSSVMQIVGCLDDAAIGSDGNAVYEIAYQVIWVCLVEESALFLRYVFERLTR-DRQDQMFKLLRHLIRFVPRLPQQAAFALYNSIIGYIMFYVRSSNELKQELVGSALSVLWMVVHSVHGIMFKDLKQILRKEQCDASILLTANVPAAKKIVVHGPADDDYNIPSQFPVQEDT---LFCQLLKEALDYYPIDEKNTSHYCLVDYKSSKILNPNWYIRDLYFFKRSQYPEVRLMLMRPEESFLALQKQELTKKFVEIGKVHLTWAILKNV--DMVVQRVVFLHEELMKLPSFPRKALEVDLDLHHGGEYGKVLLGLDVLHKFMWVRLIARMFEAMAGNFAYSADIQLFLNVLSGASILHAEDSCIMRYVMATFINAAFNFKNIFSTNGYFMIMPTLLQVYSLHQTNKLITTTIEYAVKQFYLLNRKPFILQMFGSVSAILDTDEDGTYGEAHKVQSSCLFNLLLSLEDPSPDPLNIAELVKEPKPLKAIDFCYHDEDDDVTVLDCITLCVMVVSYSAESTRGYQMLIILEAILPCYLQ---QIQSPSYIPLQGKSERDI----ILQLAVAIRTMVHNCEGLAKSYNGPYRNSPEHKGSSQ--RNCSRGPPCSPGLDFEEETHPKYMTDAR-TKNMMDSAEDSEMIRTEYRR------PRDVLLSVVADFLTKSTVRLAELAKKMPSDTKPTEVLDAKCHIRLADIAHSLLKVSPYDPESMACRGLQRYMQAVLPRAEWSNDTLRN--ALVTILRRIDKVFLKISKKPSIRRNTDWEAAAGLLKGIHETIIRHSYVLHWQQMKTLISTVQNLIV--------------------NEPGIPEGVSSAG-------AALMSQNPPAFFCSAVVRLVALQVVSPVDCFSLVQICGGSSE-FATQEKAEGFLMHLIMPLCLKVCSGRGVSDVGELKMSDVSFLLTAVL----------------------NAMSPPA---GRTGQAVSQINRV--------TGDLRAGSLTFTG-SRDAKRPARI------------------------SGSLYQAAFLALRIVCICFESRLSNEWPRIVRVMRDLGRRNEAAPDLWSFMEFVVTHRTPLYIVLLPFILHKIS 2953 HSP 2 Score: 216.083 bits (549), Expect = 4.069e-55 Identity = 162/506 (32.02%), Postives = 251/506 (49.60%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDL-ESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSA-IPMSGDHQFMNNTN-KKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPK-SRTISLKEPI-YETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESI-VGEIGQINTEIHPAPGNRRISFAF------SLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K+RK + ++ GM SF+L++ PG P+PQLVA++LDL ++P++ARA LLE A+FV CNKG+WP+WM+ GSY S A I ++ Q ++ T+ ++ +QR AG+MFH WAE +GARLE L E+ N S + D K REL DEEE+FLD+++VNP G+ CP++LK + LL IT +LR+T+ LPK S+ I +P +E Y + + + + + TS S++SI G G +E R+ISF S +SSN +L + G +AR+ P TSA+ F+ T ++T GS +RR L+ RR + + T S ++ S+ R ++S+ + + ES + P + +E D+ + +MPW++ + + N+ C H +CHP CY+R R C RL+ A + VY
Sbjct: 1179 KERKLVPTEPVRVGMLRLSFLLETCAPGSFPDPQLVAAVLDLPQAPLVARATFLLECAHFVHLCNKGQWPAWMKQNV-GSYRASGANINLNQMKQQVSQTSARRTHILQRAAGKMFHQWAEMVGARLEEILFTERLQYEAVNAS-LTDPEKQRELLQQDEEEDFLDETSVNPHGNDCPHSLKLIACVLLFEITAFLRDTYLMLPKTSKLIHRDKPAPWEKVYREANRRWSMALSSMGHSQTS---------------AQSLQSIAAGNDGAGQSE-------RKISFVLHEPDNESENSSNTTLTK---EGEEARR-PTTSAVRPFL------LRRGTATTTG----------GSFKRRS-------LKLRRNTKDSKDIET-----------DFNMQSRRKVSSLSDRSDTSEQGMISGGEESPGILSDDQQPESP----------TDSNENDDTAKNMPWLKAIIDLMSSYNYYCTHKGYCHPFCYKRHMRSCTRLVKATRKVY 1612 HSP 3 Score: 143.665 bits (361), Expect = 3.710e-33 Identity = 78/213 (36.62%), Postives = 114/213 (53.52%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFF------LNKNT------------RDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMH-CASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDND----------RENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCR 663
+P+ +Q+FL Q F L+++T AC S E+VLVQNI GLSP + + ++ RW+ ++ A PHVMH CA+LL ++ P ETK++Y++ WI++ AA EC D++ E K YL + I LFVYLFAP++ + ES FQ +LENG+ +W + + + P CFTAPVK K R
Sbjct: 53 LPVSVQTFLWRQIAPFIRPKLGKLHESTCLFCQHAPGHHESKEACKSFEKVLVQNIQFGLSPPLTKGLGVIPRWRLLQGALPHVMHACAALLYNRVKDMQAIGP---VETKLLYTMQWILLYAAEECADDEGGEDLGLGDAAEPKSKSIDQYLFSVPTITLFVYLFAPIIHHLKESDFQNFRLENGIKLWQGMWDNRAPGAPCFTAPVKPKAR 262 HSP 4 Score: 97.8265 bits (242), Expect = 2.348e-19 Identity = 80/278 (28.78%), Postives = 131/278 (47.12%), Query Frame = 1
Query: 2998 GMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASL-KPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVW-RKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDL---HNRTSSLSAALVATELLQQMAANNQNYKPGKKNI--FKRYSSAV 3810
G ++I+M I + +++LGC H C + + G + R Q + L ++ + ++ + F+ M + L +++++ HA+ FC DP+SL P S+ Y F+ ++G +E + +PLV R V + KDL EN LY DIRQL+ Y K HG FR V L+G+L V R K+G + + I + S D+ RS L TSS A+L+ TE A ++YK + + F+R ++ V
Sbjct: 792 GEHAHEISMSITRRALQVLGC--PHGCNDGVR-------GPPADFLRNQCQKILSRMLRQAGQRTKRFMQEMVKTSPLPELIDYFHAFLAFCVDPSSLLSPL---SQGGYSTNFSGGMSGG----AEAQVVGAVFKPLVSRFVEASKDLKGPENIALYGDIRQLVTYVKGAHGGPFRLVALSGILAVTPRPHKKGPSAQTTRVIRHIPQANANQSLQNDD----NRSQRRLLLKKRSTSSACASLLETE------ACEEHYKTSQSPLSNFRRRTTGV 1043 HSP 5 Score: 57.3806 bits (137), Expect = 3.625e-7 Identity = 48/169 (28.40%), Postives = 74/169 (43.79%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLXXXXXXXXXXXXXXXXTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSS 1773
D A+ LD+AVLRCLF W E G++W L+YL+ RL +I E ++ Q + KRS S + EI S +Q P G DS + + + DP ++A + + K++KM D + F + F K+E + D +S
Sbjct: 425 DVSAATFLDVAVLRCLFISHWQEEGIFWSLQYLYNRLSDIGEEAAITLNQPR-------KRSNSLPIPQIEI--SLYQGP--GSNSRDSPGSSVVKDY----IEIPDPSPTVTACVAEEPQSAPSTTERRGSEKKKRVKMADLRA-FVETKMFSKSEKNLEKVGLDTNS 577
BLAST of Protein unc-80 vs. Ensembl Zebrafish
Match: unc80 (unc-80 homolog (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-140106-167]) HSP 1 Score: 741.88 bits (1914), Expect = 0.000e+0 Identity = 446/1313 (33.97%), Postives = 724/1313 (55.14%), Query Frame = 1
Query: 6175 SVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYK--IKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTE-----SCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
S E +D +L Y+ N V L+ +++ K A +L ED++ DI+P AWELL+ D + A+AA + +L A+K+P +++ E H++ QR++++L+F ++W R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + + + + +K+F + +R Q+ E + K + EE++R+ R+ +T I ++A +E S + E ++ N RRLS + + N RN S+R GS+ +S + V EDD+N + LT ++ LQ Q VFP +CAA +PI+HL++DG+V DGVAV +A+ V+W CL+ED L LR+ LE+LT +DEL+Y+LRKL+ + +LP Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F+ K EIG+V+F S+ + P+ +H+ L ++L + PSFPR A+++EF+L++ LGK+L+G+D LHK+ W +L+ +F MPS +PW +I LFLN+FNG L+LH ED+A+LR A I + HF +FS++GY I+PT+L+ Y+ N +L++ I F C+QFYILHR PFILQ+F S++ ++F S + ++D+L ++ + D+L+ L+L+ KPL++LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ + SN + S + E AI LA S++ L+ + + LTR P D+ N++ + ++ LLEEG+ ++ DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R++ E+ P DW E+++ AL ++ RL+R NKI K RR ++W++ ++LI+ + L + R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ A+ +Q+L+ + L F T + + N++IP +L G+G KDS + ++ + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1556 SSAEGKKDTGMLKYIRNQVMTLSPAPLSLLIKAAPILTEDMYGDILPAAWELLMSVDEHMAAAAAALFLLCAVKVPDGVTEMMMAEFHHQEACQRINSILKFYTVWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPILGMPCVPIFDPPWVPVNAGTVPDAITE--DQSKSFSARAVSRSHQRAEHILKNMQQEEEKRRLGREASIITAIPIAQEACYEPTCSPPPEQEE-----------EEDVVNLTSRRLSVSPSCASSNSH-RNYSFRRGSV-WSVRSVVSAEDDENTTELTP---THHMLQPPQAVFPPCICAAVLPIVHLMEDGEVREDGVAVCAVAQQVLWNCLIEDPALVLRHFLEKLTVSNRQDELMYMLRKLLLNIGDLPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPEARSANYFLMDKRWNLIHYAKTYVRDIYPFRRSVSPQLNLVHMLPEKGQELIQKQVFSRKLEEIGRVLFIISLTQRMPAMHKQSHVSMLQEDLLRLPSFPRSAIDAEFTLFNE-PLGKELFGLDTLHKVLWIKLLEEMFLGMPSEYPWGDEIMLFLNVFNGALLLHPEDSALLRQYSATAINTAVHFNHLFSLSGYQWILPTMLQTYADYESNPLLRRGIEFCCRQFYILHRKPFILQLFASVAPLLEFTTRTSTGLSKGVSSQCLFDLLVSLEGETADSLDALELVKAEKPLRSLDFCYGNEDLAFSISEAIKLCVTVVAYAPESYRSLQMLMVLEALVPCYLQKM---------KSNIQTLESASAARDEIAAIAALATSLQALLYSVETLTRPMTAPQMSRSDQGHKGATTANHAMSGGPNTRDN-----LHLLEEGQ----GILREELDERIAREEFR-----RPRESVLNICTEFYKHCGPRLKILQNVAGEPRVTALELLDIKSHMRLAEIAHSLLKLAPYDTLTMESRGLRRYITEMLPITDWSTEAIR--PALILILKRLDRMFNKIHKMPTLRRQVEWEAASSLIEGICLTLHRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVAMQIQALKDDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPHLEQPEVFLLLQTVINILLPPRIISTSRTKNFVLDASPAHCSTPGDTGKDLRREGLAESTSQAA 2789 HSP 2 Score: 151.369 bits (381), Expect = 1.851e-35 Identity = 80/231 (34.63%), Postives = 130/231 (56.28%), Query Frame = 1
Query: 79 KAFDESNKSN--YIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN----------------------------------DRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
K+ D+S++ N IP IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC S+L+ R K + K+ + ETK++++LHW++++AA EC E + + Y +++ ++LFV+LFAPL+++I ES T +L GL IW P+ ++QPD+ F+A +K
Sbjct: 5 KSLDDSDQENCRGIPFPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALTEAIQSISRWELVQAALPHVLHCTSILLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAAQECHQEPGLVHGWSGGSSGSGSAYLQPMGNQGLTDHNGSTPEETEYARAKLYHKNMATVELFVFLFAPLINRIKESDL-TFRLAGGLVIWQPMWEHRQPDVPAFSALIK 232 HSP 3 Score: 136.732 bits (343), Expect = 5.819e-31 Identity = 85/215 (39.53%), Postives = 127/215 (59.07%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNI-SEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYE 4872
K++ ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L +E A FV RCN+G WP WM+ G ++N + +S + NK+ +Q A + F+ W +A+G RL + + +NI I DE R + DE+E++LDD+TVNP CP+ALK QLLL ITT+LRET LP+ RT EP+ +
Sbjct: 1109 KNKNIVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARASLFVECARFVHRCNRGNWPEWMK----GHHVNITKRGLSRGRSPVAG-NKRNTKLQWNAAKHFYQWGDAIGTRLSEICHSDSESP--ANILGFIYDEESKRRAKKEDEDEDYLDDNTVNPTKCGCPFALKMAACQLLLEITTFLRETFPCLPRPRT----EPLVD 1312 HSP 4 Score: 92.4337 bits (228), Expect = 1.200e-17 Identity = 62/191 (32.46%), Postives = 98/191 (51.31%), Query Frame = 1
Query: 2989 NSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTH----ECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGML 3549
N +S + +A+ ++IK++K LGC Y C + G + + R Q + CL LYK+ +F+ + SL++IV+FLHA GFC +P + AG NN+ ++S+ + E V + + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L
Sbjct: 754 NKTSLSTHWLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRTQVNISAQNCLTTLYKLDKVQFRQTMKEYVNKDSLNNIVDFLHALLGFCMEPITDNKAGFG--NNFTTGGDKSLA----QSMEAVVVGCMFKSLITRCASTTHELHSSENLGLYCDIRQLVQFIKESHGNVFRRVALSALL 929 HSP 5 Score: 70.8626 bits (172), Expect = 4.132e-11 Identity = 24/53 (45.28%), Postives = 36/53 (67.92%), Query Frame = 1
Query: 5554 DNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
DN+ +M W+ ++ N+ +F+C HVD+CHP CY+R R C RL+ AVK +Y
Sbjct: 1460 DNYHRNMSWLHIMILLCNQQSFICTHVDYCHPRCYQRHSRSCARLVRAVKLLY 1512 HSP 6 Score: 66.6254 bits (161), Expect = 8.163e-10 Identity = 42/160 (26.25%), Postives = 75/160 (46.88%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ W F+DFIV R PIF+ L PF++ K+ + PA E+Q E + I ++ +P C++++ E + +L+ +K+ S Y + V + AY
Sbjct: 2789 AYLALKVVLVCFERQLGNQWYKLSLQVKEMALRKVGGLAFWDFIDFIVRTRIPIFILLRPFIQCKLLTQ-----------------PA-----ESQEEITARHHIAEQLERRFIPRSLCKSSLFAEFSNELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2926 HSP 7 Score: 56.225 bits (134), Expect = 1.065e-6 Identity = 27/85 (31.76%), Postives = 51/85 (60.00%), Query Frame = 1
Query: 2365 EPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKK 2619
EP+ L RS +D+ INY +E+ + + G+ ++I NG ++ +L+AL+S++ S RIC+ ++ + CL +G+ +KK
Sbjct: 605 EPLACSNLPRSLTDSCINYTSLEDRDTIEGTNNFILKNGMLDLMAVLRALYSILTHDISSRICDVSLNIIDCLLQLGVVPSVMKK 689
BLAST of Protein unc-80 vs. Ensembl Zebrafish
Match: unc80 (unc-80 homolog (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-140106-167]) HSP 1 Score: 741.11 bits (1912), Expect = 0.000e+0 Identity = 446/1313 (33.97%), Postives = 725/1313 (55.22%), Query Frame = 1
Query: 6175 SVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYK--IKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTE-----SCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
S E +D +L Y+ N V L+ +++ K A +L ED++ DI+P AWELL+ D + A+AA + +L A+K+P +++ E H++ QR++++L+F ++W R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + + + + +K+F + +R Q+ E + K + EE++R+ R+ +T I ++A +E S + E +++ N RRLS + + N RN S+R GS+ +S + V EDD+N + LT ++ LQ Q VFP +CAA +PI+HL++DG+V DGVAV +A+ V+W CL+ED L LR+ LE+LT +DEL+Y+LRKL+ + +LP Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F+ K EIG+V+F S+ + P+ +H+ L ++L + PSFPR A+++EF+L++ LGK+L+G+D LHK+ W +L+ +F MPS +PW +I LFLN+FNG L+LH ED+A+LR A I + HF +FS++GY I+PT+L+ Y+ N +L++ I F C+QFYILHR PFILQ+F S++ ++F S + ++D+L ++ + D+L+ L+L+ KPL++LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ + SN + S + E AI LA S++ L+ + + LTR P D+ N++ + ++ LLEEG+ ++ DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R++ E+ P DW E+++ AL ++ RL+R NKI K RR ++W++ ++LI+ + L + R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ A+ +Q+L+ + L F T + + N++IP +L G+G KDS + ++ + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1487 SSAEGKKDTGMLKYIRNQVMTLSPAPLSLLIKAAPILTEDMYGDILPAAWELLMSVDEHMAAAAAALFLLCAVKVPDGVTEMMMAEFHHQEACQRINSILKFYTVWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPILGMPCVPIFDPPWVPVNAGTVPDAITE--DQSKSFSARAVSRSHQRAEHILKNMQQEEEKRRLGREASIITAIPIAQEACYEPTCSPPPEQEEE----------VEDVVNLTSRRLSVSPSCASSNSH-RNYSFRRGSV-WSVRSVVSAEDDENTTELTP---THHMLQPPQAVFPPCICAAVLPIVHLMEDGEVREDGVAVCAVAQQVLWNCLIEDPALVLRHFLEKLTVSNRQDELMYMLRKLLLNIGDLPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPEARSANYFLMDKRWNLIHYAKTYVRDIYPFRRSVSPQLNLVHMLPEKGQELIQKQVFSRKLEEIGRVLFIISLTQRMPAMHKQSHVSMLQEDLLRLPSFPRSAIDAEFTLFNE-PLGKELFGLDTLHKVLWIKLLEEMFLGMPSEYPWGDEIMLFLNVFNGALLLHPEDSALLRQYSATAINTAVHFNHLFSLSGYQWILPTMLQTYADYESNPLLRRGIEFCCRQFYILHRKPFILQLFASVAPLLEFTTRTSTGLSKGVSSQCLFDLLVSLEGETADSLDALELVKAEKPLRSLDFCYGNEDLAFSISEAIKLCVTVVAYAPESYRSLQMLMVLEALVPCYLQKM---------KSNIQTLESASAARDEIAAIAALATSLQALLYSVETLTRPMTAPQMSRSDQGHKGATTANHAMSGGPNTRDN-----LHLLEEGQ----GILREELDERIAREEFR-----RPRESVLNICTEFYKHCGPRLKILQNVAGEPRVTALELLDIKSHMRLAEIAHSLLKLAPYDTLTMESRGLRRYITEMLPITDWSTEAIR--PALILILKRLDRMFNKIHKMPTLRRQVEWEAASSLIEGICLTLHRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVAMQIQALKDDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPHLEQPEVFLLLQTVINILLPPRIISTSRTKNFVLDASPAHCSTPGDTGKDLRREGLAESTSQAA 2721 HSP 2 Score: 150.984 bits (380), Expect = 2.489e-35 Identity = 80/231 (34.63%), Postives = 130/231 (56.28%), Query Frame = 1
Query: 79 KAFDESNKSN--YIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN----------------------------------DRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
K+ D+S++ N IP IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC S+L+ R K + K+ + ETK++++LHW++++AA EC E + + Y +++ ++LFV+LFAPL+++I ES T +L GL IW P+ ++QPD+ F+A +K
Sbjct: 5 KSLDDSDQENCRGIPFPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALTEAIQSISRWELVQAALPHVLHCTSILLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAAQECHQEPGLVHGWSGGSSGSGSAYLQPMGNQGLTDHNGSTPEETEYARAKLYHKNMATVELFVFLFAPLINRIKESDL-TFRLAGGLVIWQPMWEHRQPDVPAFSALIK 232 HSP 3 Score: 136.732 bits (343), Expect = 5.987e-31 Identity = 83/206 (40.29%), Postives = 123/206 (59.71%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNI-SEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRT 4845
K++ ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L +E A FV RCN+G WP WM+ G ++N + +S + NK+ +Q A + F+ W +A+G RL + + +NI I DE R + DE+E++LDD+TVNP CP+ALK QLLL ITT+LRET LP+ RT
Sbjct: 1109 KNKNIVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARASLFVECARFVHRCNRGNWPEWMK----GHHVNITKRGLSRGRSPVAG-NKRNTKLQWNAAKHFYQWGDAIGTRLSEICHSDSESP--ANILGFIYDEESKRRAKKEDEDEDYLDDNTVNPTKCGCPFALKMAACQLLLEITTFLRETFPCLPRPRT 1307 HSP 4 Score: 92.4337 bits (228), Expect = 1.226e-17 Identity = 62/191 (32.46%), Postives = 98/191 (51.31%), Query Frame = 1
Query: 2989 NSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTH----ECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGML 3549
N +S + +A+ ++IK++K LGC Y C + G + + R Q + CL LYK+ +F+ + SL++IV+FLHA GFC +P + AG NN+ ++S+ + E V + + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L
Sbjct: 754 NKTSLSTHWLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRTQVNISAQNCLTTLYKLDKVQFRQTMKEYVNKDSLNNIVDFLHALLGFCMEPITDNKAGFG--NNFTTGGDKSLA----QSMEAVVVGCMFKSLITRCASTTHELHSSENLGLYCDIRQLVQFIKESHGNVFRRVALSALL 929 HSP 5 Score: 71.2478 bits (173), Expect = 3.698e-11 Identity = 39/114 (34.21%), Postives = 57/114 (50.00%), Query Frame = 1
Query: 5374 SLRAASHT-RIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
SL ++SHT + + K+SSQ S P + ST VE DN+ +M W+ ++ N+ +F+C HVD+CHP CY+R R C RL+ AVK +Y
Sbjct: 1347 SLNSSSHTLKSDTGCEEKKSSQDPWSASEPSIEPEGQGSTGGVE-----------------DNYHRNMSWLHIMILLCNQQSFICTHVDYCHPRCYQRHSRSCARLVRAVKLLY 1443 HSP 6 Score: 66.6254 bits (161), Expect = 7.945e-10 Identity = 42/160 (26.25%), Postives = 75/160 (46.88%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ W F+DFIV R PIF+ L PF++ K+ + PA E+Q E + I ++ +P C++++ E + +L+ +K+ S Y + V + AY
Sbjct: 2721 AYLALKVVLVCFERQLGNQWYKLSLQVKEMALRKVGGLAFWDFIDFIVRTRIPIFILLRPFIQCKLLTQ-----------------PA-----ESQEEITARHHIAEQLERRFIPRSLCKSSLFAEFSNELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2858 HSP 7 Score: 56.6102 bits (135), Expect = 9.856e-7 Identity = 27/85 (31.76%), Postives = 51/85 (60.00%), Query Frame = 1
Query: 2365 EPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKK 2619
EP+ L RS +D+ INY +E+ + + G+ ++I NG ++ +L+AL+S++ S RIC+ ++ + CL +G+ +KK
Sbjct: 605 EPLACSNLPRSLTDSCINYTSLEDRDTIEGTNNFILKNGMLDLMAVLRALYSILTHDISSRICDVSLNIIDCLLQLGVVPSVMKK 689
BLAST of Protein unc-80 vs. Ensembl Zebrafish
Match: unc80 (unc-80 homolog (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-140106-167]) HSP 1 Score: 484.182 bits (1245), Expect = 1.051e-142 Identity = 354/1235 (28.66%), Postives = 577/1235 (46.72%), Query Frame = 1
Query: 7195 VATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNII---------RNSSH-------------------------YVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTE-----SCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILK---------DNLSRRNLDWDSMTN--LIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
V +A+ V+W CL+ED L LR+ LE+LT +DEL+Y+LRKL+ + +LP Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I R+S H YVRD Y F+R+ P+L L M PE G L+Q+ F+ K EIG+V+F S+ + P+ +H+ L ++L + PSFPR A+++EF+L++ LGK+L+G+D LHK+ W +L+ +F MPS +PW +I LFLN+FNG L+LH ED+A+LR A I + HF +FS++GY I+PT+L+ + L K + C ++D+L ++ + D+L+ L+L+ KPL++LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ + SN + S + E AI LA S++ L+ + + LTR P D+ N++ + ++ LLEEG+ ++ DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R++ E+ P DW E+++ AL ++ RL+R NKI K L R W + + LI + R + D ++M + P ++ + L + S Y P FS V++ A+ +Q+L+ + L F T + + N++IP +L G+G KDS + ++ + +++ L LP +I T + F+ + A+ G T K + + +S + ++LALKV ++C+ R Q +S + ++ +K GG+ W F+DFIV R PIF+ L PF++ K+ + PA E+Q E + I ++ +P C++++ E + +L+ +K+ S Y + V + AY
Sbjct: 206 VCAVAQQVLWNCLIEDPALVLRHFLEKLTVSNRQDELMYMLRKLLLNIGDLPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPEARSANYFLMDKRWNLIHYAKVGCGGRHSKHANCVFSLVNTGLFVCWLFGATLHQTYVRDIYPFRRSVSPQLNLVHMLPEKGQELIQKQVFSRKLEEIGRVLFIISLTQRMPAMHKQSHVSMLQEDLLRLPSFPRSAIDAEFTLFNE-PLGKELFGLDTLHKVLWIKLLEEMFLGMPSEYPWGDEIMLFLNVFNGALLLHPEDSALLRQYSATAINTAVHFNHLFSLSGYQWILPTMLQTRTST----GLSKGVSSQC---------------------------------------LFDLLVSLEGETADSLDALELVKAEKPLRSLDFCYGNEDLAFSISEAIKLCVTVVAYAPESYRSLQMLMVLEALVPCYLQKM---------KSNIQTLESASAARDEIAAIAALATSLQALLYSVETLTRPMTAPQMSRSDQGHKGATTANHAMSGGPNTRDN-----LHLLEEGQ----GILREELDERIAREEFR-----RPRESVLNICTEFYKHCGPRLKILQNVAGEPRVTALELLDIKSHMRLAEIAHSLLKLAPYDTLTMESRGLRRYITEMLPITDWSTEAIRP--ALILILKRLDRMFNKIHKMPTLRCVHPQALCSRATRWLTGKHQCLICKLRDPTDRGNGSGMLPDKGEVMGVV--------GPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVAMQIQALKDDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPHLEQPEVFLLLQTVINIL------------LPPRII----------------STSRTKNFVLDASPAHCST-----------PGDTGKDLRREGLAESTS---------------------QAAYLALKVVLVCFERQLGNQWYKLSLQVKEMALRKVGGLAFWDFIDFIVRTRIPIFILLRPFIQCKLLTQ-----------------PA-----ESQEEITARHHIAEQLERRFIPRSLCKSSLFAEFSNELKILKEAVHSGSAYQGKTSISTVGTSTSAY 1246 HSP 2 Score: 473.781 bits (1218), Expect = 3.818e-139 Identity = 361/1292 (27.94%), Postives = 594/1292 (45.98%), Query Frame = 1
Query: 6373 VVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIH--LLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNII---------RNSSH-------------------------YVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTE-----SCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILK---------DNLSRRNLDWDSMTN--LIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
+ +L A+K+P +++ E H++ QR++++L+F ++W R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + + + +K+F + +R Q+ E + K + EE++R+ R+ +T I ++A +E S P P QEE H P + G C ++ N CV ++CA + ++ L++D A + H + + V + L Y+L +L + + +LP Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I R+S H YVRD Y F+R+ P+L L M PE G L+Q+ F+ K EIG+V+F S+ + P+ +H+ L ++L + PSFPR A+++EF+L++ LGK+L+G+D LHK+ W +L+ +F MPS +PW +I LFLN+FNG L+LH ED+A+LR A I + HF +FS++GY I+PT+L+ + L K + C ++D+L ++ + D+L+ L+L+ KPL++LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ + SN + S + E AI LA S++ L+ + + LTR P D+ N++ + ++ LLEEG+ ++ DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R++ E+ P DW E+++ AL ++ RL+R NKI K L R W + + LI + R + D ++M + P ++ + L + S Y P FS V++ A+ +Q+L+ + L F T + + N++IP +L G+G KDS + ++ + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 3 LFLLCAVKVPDGVTEMMMAEFHHQEACQRINSILKFYTVWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPILGMPCVPIFDPPWVPVNAGTVPDA--ITEDQSKSFSARAVSRSHQRAEHILKNMQQEEEKRRLGREASIITAIPIAQEACYEPTCS---------------PPPEQEEEA-------------------------HPVPPVTHTETTPSAGALCGQCGQWSVLKNALF----CV--PTVCAVAQQVLWNCLIEDP---------ALVLRHFLEKLTVSNRQDELMYMLRKL----------------LLNIGDLPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPEARSANYFLMDKRWNLIHYAKVGCGGRHSKHANCVFSLVNTGLFVCWLFGATLHQTYVRDIYPFRRSVSPQLNLVHMLPEKGQELIQKQVFSRKLEEIGRVLFIISLTQRMPAMHKQSHVSMLQEDLLRLPSFPRSAIDAEFTLFNE-PLGKELFGLDTLHKVLWIKLLEEMFLGMPSEYPWGDEIMLFLNVFNGALLLHPEDSALLRQYSATAINTAVHFNHLFSLSGYQWILPTMLQTRTST----GLSKGVSSQC---------------------------------------LFDLLVSLEGETADSLDALELVKAEKPLRSLDFCYGNEDLAFSISEAIKLCVTVVAYAPESYRSLQMLMVLEALVPCYLQKM---------KSNIQTLESASAARDEIAAIAALATSLQALLYSVETLTRPMTAPQMSRSDQGHKGATTANHAMSGGPNTRDN-----LHLLEEGQ----GILREELDERIAREEFR-----RPRESVLNICTEFYKHCGPRLKILQNVAGEPRVTALELLDIKSHMRLAEIAHSLLKLAPYDTLTMESRGLRRYITEMLPITDWSTEAIR--PALILILKRLDRMFNKIHKMPTLRCVHPQALCSRATRWLTGKHQCLICKLRDPTDRGNGSGMLPDKGEVMGVV--------GPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVAMQIQALKDDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPHLEQPEVFLLLQTVINILLPPRIISTSRTKNFVLDASPAHCSTPGDTGKDLRREGLAESTSQAA 1109
BLAST of Protein unc-80 vs. Ensembl Xenopus
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:NCBI gene;Acc:779473]) HSP 1 Score: 739.954 bits (1909), Expect = 0.000e+0 Identity = 445/1313 (33.89%), Postives = 721/1313 (54.91%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNE-AAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF---QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIA------PHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
E +D +L Y+ + V +L+ +++ K A +L E++++DI P AWELLL D + +AA + +L A+K+P ++ E QH + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W QS+ VQ NE +K+F + +R Q+ E + K + EE++++ R+ +T + ++A +E S S+ +E N RRLS + + + RN S+R GS+ +S + V ED+++ + T +QP Q VFP+ +CAA +PI+HL++DGDV DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NI + Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P +H+ L ++L + PSFPR A+++EFSL++ GK+L+G+D L K W +L+ +F MPS FPW ++ LFL++FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VY+ N L++AI F C+QFY+LHR PF+LQ+F S++ +D S+ + ++D+L+++ + D L+IL+L+ +PLK+LDFCY NE+ ++S+ E + LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T S + E A LA S++ L+ + + LTR P GD+ N++ + + + ++ LLEEG+ G + IA P E++L + +FY C RL N GE + +LELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + ++ + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1632 EGKKDSGMLKYIRHQVMSLSPAPLSLLIKAAPILTEEMYSDIQPAAWELLLSVDEHMAGAAAAMFLLCAVKVPDAVSDMLTSEFQHPETVQRINAILKFHTLWRFRYQVWPRMEEGAQQIYKIPPPSINFTLPSPILGMPSVPMFDPPWVP---QSSGSVQDPINEDQSKSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPVTQEACYEPTCSP-----------NSEQEEEEEPTNLNSRRLSVS-PSCTSSTSHRNYSFRRGSV-WSIRSAVSAEDEEHATEHTGNHHVSQP---PQPVFPACICAAVLPIVHLMEDGDVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELIYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIADSQSANYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMPPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPPAHKQSHVSMLQEDLLRLPSFPRSAVDAEFSLFNDPQAGKELFGLDTLQKSLWIKLLEEMFLGMPSEFPWGDEMMLFLSVFNGALILHPEDSALLRQYAATAINTAVHFNHLFSLSGYQWILPTMLQVYADYESNPQLRQAIEFTCRQFYVLHRKPFVLQLFASVAPLLDLPDGVSSGSSSKGVSAQCLFDLLQSLEGETADILDILELVKAERPLKSLDFCYGNEDMAFSISECIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQLETVSAAREEIAATAALATSLQALLYSVEALTRPMTAPQMSRGDQGHKGATTANHTMSAGANLRDN-----LHLLEEGQ---------------GLPREELDERIAREEFRRPRESLLNICTEFYKHCGPRLKILQNLAGEPRVTSLELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLKRYIMEMLPITDWTSEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVFLLLQTVINILLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRREGLAESTSQAA 2864 HSP 2 Score: 173.711 bits (439), Expect = 4.832e-42 Identity = 147/512 (28.71%), Postives = 225/512 (43.95%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQ---------ILDEEENFLDDS---TVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETS---YNIDSTQD-HKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W + +GARL E + + + I DE R L+ +E F + +VNP CP+ALK QLLL ITT+LRET LP+ R EP+ + +D D H+ ++I + G+ + DS D SLHSS+++L ++G + +K P RKI R + G R ++ GS +++ RA GSL++A TR S +E SQ TV + SP S G + SE +++ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y
Sbjct: 1173 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNIAKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDVIGARLNEICHSESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSKETPFTTRNPACSVNPTKCGCPFALKMSACQLLLEITTFLRETFPCLPRPRA----EPLVDLETCRLRLDPEMDRHRYERKISF-------AGILDENEDSKD-------------------------------SLHSSSHTLK--SDTGGEEKKVPS------------------------------RKIRIGGSRLLQIKGTRSFRVKK-GGSL---SSIRRA------GSLKSAKLTRQDSGSENEEIQLSQ------SRDTVTDIEGSPWSTSEPSIEPEGGNISSE-ESYHHNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLY 1585 HSP 3 Score: 152.14 bits (383), Expect = 1.858e-35 Identity = 84/214 (39.25%), Postives = 129/214 (60.28%), Query Frame = 1
Query: 91 ESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDR-------ENKCSDGIS---------------YLHD-LSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
E + IPL IQ FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C +DR EN+ S G S +L + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ Y+QP++ FTA VK
Sbjct: 11 EQERPRGIPLAIQIFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDC-SHDRFSAFIHQENQGSPGHSRQSNTNEEDENNRRKFLQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEYRQPEVPAFTALVK 220 HSP 4 Score: 102.449 bits (254), Expect = 1.684e-20 Identity = 64/200 (32.00%), Postives = 104/200 (52.00%), Query Frame = 1
Query: 3001 MSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQ 3600
++ + +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ +++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+ + Q
Sbjct: 762 VTTHKLALTMLIKLVKSLGCAY--GCGEGHR-------GLSGDRLRNQAQSCLTKLYKLDKVQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNRAGFG--NNFTTMDNKSTA----QSVEGIIVSSMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLTPGKKSEDGEQ 946 HSP 5 Score: 72.4034 bits (176), Expect = 2.506e-11 Identity = 44/160 (27.50%), Postives = 76/160 (47.50%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW F+DFIV R PIF+ L PF++ K+ + ETQ E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2864 AYLALKVILVCFERQLGSQWYRLSLQVKEMAIRKVGGLALWDFIDFIVRTRIPIFILLRPFIQCKLLVQPP----------------------ETQDELSARQHIADQLERRFIPRPLCKSSLINEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 3001 HSP 6 Score: 58.9214 bits (141), Expect = 2.590e-7 Identity = 34/116 (29.31%), Postives = 64/116 (55.17%), Query Frame = 1
Query: 2362 QEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGI---FEKRIKKKKPDQENSSMLSKRRNQLRNKKTKSNG 2700
EP+ L RS +D+ INY +E+ + + G+ +++ NG ++ V+LK+++ ++N S RIC+ ++ + CL +G+ EK+ +KK ++EN S K +S G
Sbjct: 593 HEPLACANLPRSLTDSCINYSSLEDTDHIDGTNNFVHKNGMLDLTVVLKSVYLVLNHDISSRICDVALNIVDCLLQLGVVPCVEKK-RKKSDNKENESASVSGSGSACGDKRQSEG 707
BLAST of Protein unc-80 vs. Ensembl Xenopus
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:NCBI gene;Acc:779473]) HSP 1 Score: 739.569 bits (1908), Expect = 0.000e+0 Identity = 445/1313 (33.89%), Postives = 721/1313 (54.91%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNE-AAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF---QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIA------PHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
E +D +L Y+ + V +L+ +++ K A +L E++++DI P AWELLL D + +AA + +L A+K+P ++ E QH + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W QS+ VQ NE +K+F + +R Q+ E + K + EE++++ R+ +T + ++A +E S S+ +E N RRLS + + + RN S+R GS+ +S + V ED+++ + T +QP Q VFP+ +CAA +PI+HL++DGDV DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NI + Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P +H+ L ++L + PSFPR A+++EFSL++ GK+L+G+D L K W +L+ +F MPS FPW ++ LFL++FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VY+ N L++AI F C+QFY+LHR PF+LQ+F S++ +D S+ + ++D+L+++ + D L+IL+L+ +PLK+LDFCY NE+ ++S+ E + LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T S + E A LA S++ L+ + + LTR P GD+ N++ + + + ++ LLEEG+ G + IA P E++L + +FY C RL N GE + +LELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + ++ + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1632 EGKKDSGMLKYIRHQVMSLSPAPLSLLIKAAPILTEEMYSDIQPAAWELLLSVDEHMAGAAAAMFLLCAVKVPDAVSDMLTSEFQHPETVQRINAILKFHTLWRFRYQVWPRMEEGAQQIYKIPPPSINFTLPSPILGMPSVPMFDPPWVP---QSSGSVQDPINEDQSKSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPVTQEACYEPTCSP-----------NSEQEEEEEPTNLNSRRLSVS-PSCTSSTSHRNYSFRRGSV-WSIRSAVSAEDEEHATEHTGNHHVSQP---PQPVFPACICAAVLPIVHLMEDGDVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELIYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIADSQSANYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMPPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPPAHKQSHVSMLQEDLLRLPSFPRSAVDAEFSLFNDPQAGKELFGLDTLQKSLWIKLLEEMFLGMPSEFPWGDEMMLFLSVFNGALILHPEDSALLRQYAATAINTAVHFNHLFSLSGYQWILPTMLQVYADYESNPQLRQAIEFTCRQFYVLHRKPFVLQLFASVAPLLDLPDGVSSGSSSKGVSAQCLFDLLQSLEGETADILDILELVKAERPLKSLDFCYGNEDMAFSISECIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQLETVSAAREEIAATAALATSLQALLYSVEALTRPMTAPQMSRGDQGHKGATTANHTMSAGANLRDN-----LHLLEEGQ---------------GLPREELDERIAREEFRRPRESLLNICTEFYKHCGPRLKILQNLAGEPRVTSLELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLKRYIMEMLPITDWTSEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVFLLLQTVINILLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRREGLAESTSQAA 2864 HSP 2 Score: 173.711 bits (439), Expect = 5.445e-42 Identity = 147/512 (28.71%), Postives = 225/512 (43.95%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQ---------ILDEEENFLDDS---TVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETS---YNIDSTQD-HKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W + +GARL E + + + I DE R L+ +E F + +VNP CP+ALK QLLL ITT+LRET LP+ R EP+ + +D D H+ ++I + G+ + DS D SLHSS+++L ++G + +K P RKI R + G R ++ GS +++ RA GSL++A TR S +E SQ TV + SP S G + SE +++ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y
Sbjct: 1173 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNIAKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDVIGARLNEICHSESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSKETPFTTRNPACSVNPTKCGCPFALKMSACQLLLEITTFLRETFPCLPRPRA----EPLVDLETCRLRLDPEMDRHRYERKISF-------AGILDENEDSKD-------------------------------SLHSSSHTLK--SDTGGEEKKVPS------------------------------RKIRIGGSRLLQIKGTRSFRVKK-GGSL---SSIRRA------GSLKSAKLTRQDSGSENEEIQLSQ------SRDTVTDIEGSPWSTSEPSIEPEGGNISSE-ESYHHNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLY 1585 HSP 3 Score: 152.14 bits (383), Expect = 1.641e-35 Identity = 82/213 (38.50%), Postives = 128/213 (60.09%), Query Frame = 1
Query: 91 ESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN------DRENKCSDGIS---------------YLHD-LSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
E + IPL IQ FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C + +EN+ S G S +L + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ Y+QP++ FTA VK
Sbjct: 11 EQERPRGIPLAIQIFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDCSHDRFSAFIHQENQGSPGHSRQSNTNEEDENNRRKFLQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEYRQPEVPAFTALVK 220 HSP 4 Score: 102.449 bits (254), Expect = 1.603e-20 Identity = 64/200 (32.00%), Postives = 104/200 (52.00%), Query Frame = 1
Query: 3001 MSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQ 3600
++ + +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ +++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+ + Q
Sbjct: 762 VTTHKLALTMLIKLVKSLGCAY--GCGEGHR-------GLSGDRLRNQAQSCLTKLYKLDKVQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNRAGFG--NNFTTMDNKSTA----QSVEGIIVSSMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLTPGKKSEDGEQ 946 HSP 5 Score: 72.4034 bits (176), Expect = 2.529e-11 Identity = 44/160 (27.50%), Postives = 76/160 (47.50%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW F+DFIV R PIF+ L PF++ K+ + ETQ E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2864 AYLALKVILVCFERQLGSQWYRLSLQVKEMAIRKVGGLALWDFIDFIVRTRIPIFILLRPFIQCKLLVQPP----------------------ETQDELSARQHIADQLERRFIPRPLCKSSLINEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 3001 HSP 6 Score: 58.9214 bits (141), Expect = 2.771e-7 Identity = 34/116 (29.31%), Postives = 64/116 (55.17%), Query Frame = 1
Query: 2362 QEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGI---FEKRIKKKKPDQENSSMLSKRRNQLRNKKTKSNG 2700
EP+ L RS +D+ INY +E+ + + G+ +++ NG ++ V+LK+++ ++N S RIC+ ++ + CL +G+ EK+ +KK ++EN S K +S G
Sbjct: 593 HEPLACANLPRSLTDSCINYSSLEDTDHIDGTNNFVHKNGMLDLTVVLKSVYLVLNHDISSRICDVALNIVDCLLQLGVVPCVEKK-RKKSDNKENESASVSGSGSACGDKRQSEG 707
BLAST of Protein unc-80 vs. Ensembl Xenopus
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:NCBI gene;Acc:779473]) HSP 1 Score: 738.799 bits (1906), Expect = 0.000e+0 Identity = 445/1313 (33.89%), Postives = 721/1313 (54.91%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNE-AAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF---QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIA------PHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
E +D +L Y+ + V +L+ +++ K A +L E++++DI P AWELLL D + +AA + +L A+K+P ++ E QH + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W QS+ VQ NE +K+F + +R Q+ E + K + EE++++ R+ +T + ++A +E S S+ +E N RRLS + + + RN S+R GS+ +S + V ED+++ + T +QP Q VFP+ +CAA +PI+HL++DGDV DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NI + Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P +H+ L ++L + PSFPR A+++EFSL++ GK+L+G+D L K W +L+ +F MPS FPW ++ LFL++FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VY+ N L++AI F C+QFY+LHR PF+LQ+F S++ +D S+ + ++D+L+++ + D L+IL+L+ +PLK+LDFCY NE+ ++S+ E + LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T S + E A LA S++ L+ + + LTR P GD+ N++ + + + ++ LLEEG+ G + IA P E++L + +FY C RL N GE + +LELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + ++ + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1599 EGKKDSGMLKYIRHQVMSLSPAPLSLLIKAAPILTEEMYSDIQPAAWELLLSVDEHMAGAAAAMFLLCAVKVPDAVSDMLTSEFQHPETVQRINAILKFHTLWRFRYQVWPRMEEGAQQIYKIPPPSINFTLPSPILGMPSVPMFDPPWVP---QSSGSVQDPINEDQSKSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPVTQEACYEPTCSP-----------NSEQEEEEEPTNLNSRRLSVS-PSCTSSTSHRNYSFRRGSV-WSIRSAVSAEDEEHATEHTGNHHVSQP---PQPVFPACICAAVLPIVHLMEDGDVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELIYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIADSQSANYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMPPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPPAHKQSHVSMLQEDLLRLPSFPRSAVDAEFSLFNDPQAGKELFGLDTLQKSLWIKLLEEMFLGMPSEFPWGDEMMLFLSVFNGALILHPEDSALLRQYAATAINTAVHFNHLFSLSGYQWILPTMLQVYADYESNPQLRQAIEFTCRQFYVLHRKPFVLQLFASVAPLLDLPDGVSSGSSSKGVSAQCLFDLLQSLEGETADILDILELVKAERPLKSLDFCYGNEDMAFSISECIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQLETVSAAREEIAATAALATSLQALLYSVEALTRPMTAPQMSRGDQGHKGATTANHTMSAGANLRDN-----LHLLEEGQ---------------GLPREELDERIAREEFRRPRESLLNICTEFYKHCGPRLKILQNLAGEPRVTSLELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLKRYIMEMLPITDWTSEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVFLLLQTVINILLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRREGLAESTSQAA 2831 HSP 2 Score: 173.711 bits (439), Expect = 4.948e-42 Identity = 147/512 (28.71%), Postives = 225/512 (43.95%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQ---------ILDEEENFLDDS---TVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETS---YNIDSTQD-HKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W + +GARL E + + + I DE R L+ +E F + +VNP CP+ALK QLLL ITT+LRET LP+ R EP+ + +D D H+ ++I + G+ + DS D SLHSS+++L ++G + +K P RKI R + G R ++ GS +++ RA GSL++A TR S +E SQ TV + SP S G + SE +++ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y
Sbjct: 1140 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNIAKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDVIGARLNEICHSESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSKETPFTTRNPACSVNPTKCGCPFALKMSACQLLLEITTFLRETFPCLPRPRA----EPLVDLETCRLRLDPEMDRHRYERKISF-------AGILDENEDSKD-------------------------------SLHSSSHTLK--SDTGGEEKKVPS------------------------------RKIRIGGSRLLQIKGTRSFRVKK-GGSL---SSIRRA------GSLKSAKLTRQDSGSENEEIQLSQ------SRDTVTDIEGSPWSTSEPSIEPEGGNISSE-ESYHHNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLY 1552 HSP 3 Score: 152.14 bits (383), Expect = 1.856e-35 Identity = 82/213 (38.50%), Postives = 128/213 (60.09%), Query Frame = 1
Query: 91 ESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN------DRENKCSDGIS---------------YLHD-LSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
E + IPL IQ FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C + +EN+ S G S +L + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ Y+QP++ FTA VK
Sbjct: 11 EQERPRGIPLAIQIFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDCSHDRFSAFIHQENQGSPGHSRQSNTNEEDENNRRKFLQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEYRQPEVPAFTALVK 220 HSP 4 Score: 102.449 bits (254), Expect = 1.740e-20 Identity = 64/200 (32.00%), Postives = 104/200 (52.00%), Query Frame = 1
Query: 3001 MSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQ 3600
++ + +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ +++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+ + Q
Sbjct: 762 VTTHKLALTMLIKLVKSLGCAY--GCGEGHR-------GLSGDRLRNQAQSCLTKLYKLDKVQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNRAGFG--NNFTTMDNKSTA----QSVEGIIVSSMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLTPGKKSEDGEQ 946 HSP 5 Score: 72.0182 bits (175), Expect = 2.569e-11 Identity = 44/160 (27.50%), Postives = 76/160 (47.50%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW F+DFIV R PIF+ L PF++ K+ + ETQ E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2831 AYLALKVILVCFERQLGSQWYRLSLQVKEMAIRKVGGLALWDFIDFIVRTRIPIFILLRPFIQCKLLVQPP----------------------ETQDELSARQHIADQLERRFIPRPLCKSSLINEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2968 HSP 6 Score: 58.9214 bits (141), Expect = 2.723e-7 Identity = 34/116 (29.31%), Postives = 64/116 (55.17%), Query Frame = 1
Query: 2362 QEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGI---FEKRIKKKKPDQENSSMLSKRRNQLRNKKTKSNG 2700
EP+ L RS +D+ INY +E+ + + G+ +++ NG ++ V+LK+++ ++N S RIC+ ++ + CL +G+ EK+ +KK ++EN S K +S G
Sbjct: 593 HEPLACANLPRSLTDSCINYSSLEDTDHIDGTNNFVHKNGMLDLTVVLKSVYLVLNHDISSRICDVALNIVDCLLQLGVVPCVEKK-RKKSDNKENESASVSGSGSACGDKRQSEG 707
BLAST of Protein unc-80 vs. Ensembl Xenopus
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:NCBI gene;Acc:779473]) HSP 1 Score: 725.702 bits (1872), Expect = 0.000e+0 Identity = 411/1135 (36.21%), Postives = 654/1135 (57.62%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNE-AAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF---QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQD-ESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIA------PHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLI 9531
E +D +L Y+ + V +L+ +++ K A +L E++++DI P AWELLL D + +AA + +L A+K+P ++ E QH + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W QS+ VQ NE +K+F + +R Q+ E + K + EE++++ R+ +T + ++A +E S S+ +E N RRLS + + + RN S+R GS+ +S + V ED+++ + T +QP Q VFP+ +CAA +PI+HL++DGDV DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NI + Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P +H+ L ++L + PSFPR A+++EFSL++ GK+L+G+D L K W +L+ +F MPS FPW ++ LFL++FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VY+ N L++AI F C+QFY+LHR PF+LQ+F S++ +D S+ + ++D+L+++ + D L+IL+L+ +PLK+LDFCY NE+ ++S+ E + LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T S + E A LA S++ L+ + + LTR P GD+ N++ + S+ L LLEEG+ G + IA P E++L + +FY C RL N GE + +LELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L+
Sbjct: 1590 EGKKDSGMLKYIRHQVMSLSPAPLSLLIKAAPILTEEMYSDIQPAAWELLLSVDEHMAGAAAAMFLLCAVKVPDAVSDMLTSEFQHPETVQRINAILKFHTLWRFRYQVWPRMEEGAQQIYKIPPPSINFTLPSPILGMPSVPMFDPPWVP---QSSGSVQDPINEDQSKSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPVTQEACYEPTCSP-----------NSEQEEEEEPTNLNSRRLSVS-PSCTSSTSHRNYSFRRGSV-WSIRSAVSAEDEEHATEHTGNHHVSQP---PQPVFPACICAAVLPIVHLMEDGDVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELIYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIADSQSANYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMPPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPPAHKQSHVSMLQEDLLRLPSFPRSAVDAEFSLFNDPQAGKELFGLDTLQKSLWIKLLEEMFLGMPSEFPWGDEMMLFLSVFNGALILHPEDSALLRQYAATAINTAVHFNHLFSLSGYQWILPTMLQVYADYESNPQLRQAIEFTCRQFYVLHRKPFVLQLFASVAPLLDLPDGVSSGSSSKGVSAQCLFDLLQSLEGETADILDILELVKAERPLKSLDFCYGNEDMAFSISECIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQLETVSAAREEIAATAALATSLQALLYSVEALTRPMTAPQMSRGDQGHKGATTANHTMSAGSLFLYGSHFRDNLHLLEEGQ---------------GLPREELDERIAREEFRRPRESLLNICTEFYKHCGPRLKILQNLAGEPRVTSLELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLKRYIMEMLPITDWTSEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLV 2679 HSP 2 Score: 183.341 bits (464), Expect = 6.758e-45 Identity = 161/540 (29.81%), Postives = 242/540 (44.81%), Query Frame = 1
Query: 4111 SGANASASKGRARNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETS---YNIDSTQD-HKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
+G A GR N F+ G ++ K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W + +GARL E + + + I DE R L+ DEEE+FLDDS+VNP CP+ALK QLLL ITT+LRET LP+ R EP+ + +D D H+ ++I + G+ + DS D SLHSS+++L ++G + +K P RKI R + G R ++ GS +++ RA GSL++A TR S +E SQ TV + SP S G + SE +++ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y
Sbjct: 1106 AGPGAGLDSGRDEEENF---FKRLGCQSFDDHITTNHETGKSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNIAKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDVIGARLNEICHSESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSSVNPTKCGCPFALKMSACQLLLEITTFLRETFPCLPRPRA----EPLVDLETCRLRLDPEMDRHRYERKISF-------AGILDENEDSKD-------------------------------SLHSSSHTLK--SDTGGEEKKVPS------------------------------RKIRIGGSRLLQIKGTRSFRVKK-GGSL---SSIRRA------GSLKSAKLTRQDSGSENEEIQLSQ------SRDTVTDIEGSPWSTSEPSIEPEGGNISSE-ESYHHNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLY 1543 HSP 3 Score: 125.176 bits (313), Expect = 2.477e-27 Identity = 76/225 (33.78%), Postives = 120/225 (53.33%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNS-------FFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN------DRENKCSDGIS---------------YLHD-LSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ FL QT +LN + + + N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C + +EN+ S G S +L + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ Y+QP++ FTA VK
Sbjct: 4 RKSSEGQEQERPRGIPLAIQIFLWRQTRYVRYFALLIYLNICNYVWLQSNYPYICITNKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDCSHDRFSAFIHQENQGSPGHSRQSNTNEEDENNRRKFLQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEYRQPEVPAFTALVK 225 HSP 4 Score: 97.4413 bits (241), Expect = 5.287e-19 Identity = 64/202 (31.68%), Postives = 105/202 (51.98%), Query Frame = 1
Query: 3001 MSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTH--ECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQ 3600
++ + +A+ ++IK++K LGC Y C + G + + R Q + CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ +++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+ + Q
Sbjct: 764 VTTHKLALTMLIKLVKSLGCAY--GCGEGHR-------GLSGDRLRNQVNAQSCLTKLYKLDKVQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNRAGFG--NNFTTMDNKSTA----QSVEGIIVSSMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLTPGKKSEDGEQ 950 HSP 5 Score: 72.0182 bits (175), Expect = 2.638e-11 Identity = 44/160 (27.50%), Postives = 76/160 (47.50%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW F+DFIV R PIF+ L PF++ K+ + ETQ E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2808 AYLALKVILVCFERQLGSQWYRLSLQVKEMAIRKVGGLALWDFIDFIVRTRIPIFILLRPFIQCKLLVQPP----------------------ETQDELSARQHIADQLERRFIPRPLCKSSLINEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2945 HSP 6 Score: 58.9214 bits (141), Expect = 2.680e-7 Identity = 34/116 (29.31%), Postives = 64/116 (55.17%), Query Frame = 1
Query: 2362 QEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGI---FEKRIKKKKPDQENSSMLSKRRNQLRNKKTKSNG 2700
EP+ L RS +D+ INY +E+ + + G+ +++ NG ++ V+LK+++ ++N S RIC+ ++ + CL +G+ EK+ +KK ++EN S K +S G
Sbjct: 595 HEPLACANLPRSLTDSCINYSSLEDTDHIDGTNNFVHKNGMLDLTVVLKSVYLVLNHDISSRICDVALNIVDCLLQLGVVPCVEKK-RKKSDNKENESASVSGSGSACGDKRQSEG 709
BLAST of Protein unc-80 vs. Ensembl Xenopus
Match: UNC80 (unc-80 homolog, NALCN channel complex subunit [Source:NCBI gene;Acc:779473]) HSP 1 Score: 723.776 bits (1867), Expect = 0.000e+0 Identity = 411/1135 (36.21%), Postives = 654/1135 (57.62%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNE-AAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF---QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQD-ESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIA------PHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLI 9531
E +D +L Y+ + V +L+ +++ K A +L E++++DI P AWELLL D + +AA + +L A+K+P ++ E QH + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W QS+ VQ NE +K+F + +R Q+ E + K + EE++++ R+ +T + ++A +E S Q ++E N RRLS + + + RN S+R GS+ +S + V ED+++ + T +QP Q VFP+ +CAA +PI+HL++DGDV DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NI + Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P +H+ L ++L + PSFPR A+++EFSL++ GK+L+G+D L K W +L+ +F MPS FPW ++ LFL++FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VY+ N L++AI F C+QFY+LHR PF+LQ+F S++ +D S+ + ++D+L+++ + D L+IL+L+ +PLK+LDFCY NE+ ++S+ E + LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T S + E A LA S++ L+ + + LTR P GD+ N++ + S+ L LLEEG+ G + IA P E++L + +FY C RL N GE + +LELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L+
Sbjct: 1522 EGKKDSGMLKYIRHQVMSLSPAPLSLLIKAAPILTEEMYSDIQPAAWELLLSVDEHMAGAAAAMFLLCAVKVPDAVSDMLTSEFQHPETVQRINAILKFHTLWRFRYQVWPRMEEGAQQIYKIPPPSINFTLPSPILGMPSVPMFDPPWVP---QSSGSVQDPINEDQSKSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPVTQEACYEPTCSP----------NSEQEEEVEEPTNLNSRRLSVS-PSCTSSTSHRNYSFRRGSV-WSIRSAVSAEDEEHATEHTGNHHVSQP---PQPVFPACICAAVLPIVHLMEDGDVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELIYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIADSQSANYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMPPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPPAHKQSHVSMLQEDLLRLPSFPRSAVDAEFSLFNDPQAGKELFGLDTLQKSLWIKLLEEMFLGMPSEFPWGDEMMLFLSVFNGALILHPEDSALLRQYAATAINTAVHFNHLFSLSGYQWILPTMLQVYADYESNPQLRQAIEFTCRQFYVLHRKPFVLQLFASVAPLLDLPDGVSSGSSSKGVSAQCLFDLLQSLEGETADILDILELVKAERPLKSLDFCYGNEDMAFSISECIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQLETVSAAREEIAATAALATSLQALLYSVEALTRPMTAPQMSRGDQGHKGATTANHTMSAGSLFLYGSHFRDNLHLLEEGQ---------------GLPREELDERIAREEFRRPRESLLNICTEFYKHCGPRLKILQNLAGEPRVTSLELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLKRYIMEMLPITDWTSEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLV 2612 HSP 2 Score: 139.813 bits (351), Expect = 9.601e-32 Identity = 93/247 (37.65%), Postives = 134/247 (54.25%), Query Frame = 1
Query: 4111 SGANASASKGRARNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRT 4845
+G A GR N F+ G ++ K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W + +GARL E + + + I DE R L+ DEEE+FLDDS+VNP CP+ALK QLLL ITT+LRET LP+ R
Sbjct: 1106 AGPGAGLDSGRDEEENF---FKRLGCQSFDDHITTNHETGKSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNIAKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDVIGARLNEICHSESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSSVNPTKCGCPFALKMSACQLLLEITTFLRETFPCLPRPRA 1341 HSP 3 Score: 125.176 bits (313), Expect = 2.593e-27 Identity = 76/225 (33.78%), Postives = 120/225 (53.33%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNS-------FFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN------DRENKCSDGIS---------------YLHD-LSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ FL QT +LN + + + N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C + +EN+ S G S +L + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ Y+QP++ FTA VK
Sbjct: 4 RKSSEGQEQERPRGIPLAIQIFLWRQTRYVRYFALLIYLNICNYVWLQSNYPYICITNKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDCSHDRFSAFIHQENQGSPGHSRQSNTNEEDENNRRKFLQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEYRQPEVPAFTALVK 225 HSP 4 Score: 97.4413 bits (241), Expect = 5.542e-19 Identity = 64/202 (31.68%), Postives = 105/202 (51.98%), Query Frame = 1
Query: 3001 MSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTH--ECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQ 3600
++ + +A+ ++IK++K LGC Y C + G + + R Q + CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ +++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+ + Q
Sbjct: 764 VTTHKLALTMLIKLVKSLGCAY--GCGEGHR-------GLSGDRLRNQVNAQSCLTKLYKLDKVQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNRAGFG--NNFTTMDNKSTA----QSVEGIIVSSMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLTPGKKSEDGEQ 950 HSP 5 Score: 72.0182 bits (175), Expect = 2.722e-11 Identity = 44/160 (27.50%), Postives = 76/160 (47.50%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW F+DFIV R PIF+ L PF++ K+ + ETQ E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2741 AYLALKVILVCFERQLGSQWYRLSLQVKEMAIRKVGGLALWDFIDFIVRTRIPIFILLRPFIQCKLLVQPP----------------------ETQDELSARQHIADQLERRFIPRPLCKSSLINEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2878 HSP 6 Score: 63.929 bits (154), Expect = 8.689e-9 Identity = 31/97 (31.96%), Postives = 50/97 (51.55%), Query Frame = 1
Query: 5422 KESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K+S S T ++ ++ SP S G + SE +++ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y
Sbjct: 1380 KDSLHSSSHTLKSDTGGEEKKEGSPWSTSEPSIEPEGGNISSE-ESYHHNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLY 1475 HSP 7 Score: 58.9214 bits (141), Expect = 2.420e-7 Identity = 34/116 (29.31%), Postives = 64/116 (55.17%), Query Frame = 1
Query: 2362 QEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGI---FEKRIKKKKPDQENSSMLSKRRNQLRNKKTKSNG 2700
EP+ L RS +D+ INY +E+ + + G+ +++ NG ++ V+LK+++ ++N S RIC+ ++ + CL +G+ EK+ +KK ++EN S K +S G
Sbjct: 595 HEPLACANLPRSLTDSCINYSSLEDTDHIDGTNNFVHKNGMLDLTVVLKSVYLVLNHDISSRICDVALNIVDCLLQLGVVPCVEKK-RKKSDNKENESASVSGSGSACGDKRQSEG 709
BLAST of Protein unc-80 vs. Ensembl Mouse
Match: Unc80 (unc-80, NALCN activator [Source:MGI Symbol;Acc:MGI:2652882]) HSP 1 Score: 740.725 bits (1911), Expect = 0.000e+0 Identity = 450/1324 (33.99%), Postives = 725/1324 (54.76%), Query Frame = 1
Query: 6151 PATNKHKSSVK-EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF-QGENSNFYK-IKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQ--NSVVLEDQDESPY-----RLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
P+ K S V E +D +L Y+ V +L+ +++ K A +L E+++ DI P AWELLL D + +AA + +L A+K+P ++ E H + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + +C + + + ++++ K+F + +R Q+ E + K + EE++++ R+ +T I ++A +E + S+P +E N RRLS + + + RN S+R GS+ +S + V ED+++ + T QP Q VFP+ +CAA +PI+HL++DG+V DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P+ +H+ L ++L + PSFPR A+++EFSL+ GK+L+G+D L K W +L+ +F MPS FPW +I LFLN+FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VYS N L++AI F C QFYILHR PF+LQ+F S++ ++F N+ K + ++D+L+++ + D L+IL+L+ KPLK+LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ + + T + E A LA S++ L+ + + LTR P D+ N++ + N+ E + + LLEEG+ + DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ ++LI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + + + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1607 PSLKKRVSDVNLEGKKDSGMLKYIRFQVMSLSPAPLSLLIKAAPILTEEMYGDIQPAAWELLLSMDEHMAGAAAAMFLLCAVKVPDAVSDMLMSEFHHAETVQRLNAVLKFHTLWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPVLGMPSVPMFDPPW-VPQCSGSVQDPINEDQS-KSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPITQEACYEPTCTP-----------NSEPEEEEEVANLTSRRLSVS-PSCTSSTSHRNYSFRRGSV-WSVRSAVSAEDEEHATEHTPNHHVPQP---PQAVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELMYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPESQSTHYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMHPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPTAHKQSHVSMLQEDLLRLPSFPRSAIDAEFSLFSDPQAGKELFGLDTLQKSLWIQLLEEMFLGMPSEFPWGDEIMLFLNVFNGALILHPEDSALLRQYAATVINTAVHFNHLFSLSGYQWILPTMLQVYSDYESNPQLRRAIEFACHQFYILHRKPFVLQLFASVAPLLEFPDAANTGSSKGVSAQCLFDLLQSLEGETTDILDILELVKAEKPLKSLDFCYGNEDLTFSISEAIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKMKR----QTSQVETVPAAREEIAATAALATSLQALLYSVEVLTRPMTAPQMSRSDQGHKGTTTANHTMSSGVNTRYPEQGAKLHFIRENLHLLEEGQ----GLPREELDERISREEFR-----RPRESLLNICTEFYKHCGPRLKILQNLAGEPRVTALELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWSAEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASSLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVLLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRKEGLAESTSQAA 2862 HSP 2 Score: 192.2 bits (487), Expect = 1.038e-47 Identity = 156/519 (30.06%), Postives = 238/519 (45.86%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQ--FMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQD-HKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVS-----TFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S N N+K +Q A ++F+ W +A+G RL E + + + I DE R L+ DEEE+FLDDSTVNP CP+ALK QLLL ITT+LRET LP+ RT L + + +D D H+ ++I + GV + DS D SLHSS++++ ++G++ +K P R+ + G LL+ + + SFQ K +L S+R R+GS++ K S Q S + TV + SP S G+S +N+ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y + R+ + ++VA
Sbjct: 1171 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNITKKGLSRGRSPTVGNKRNQK---LQWSAAKLFYQWGDAIGIRLNELCHGESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSTVNPSKCGCPFALKMAACQLLLEITTFLRETFSCLPRPRTEPLVD-LESCRLRLDPELDRHRYERKISF-------AGVLDENEDSKD-------------------------------SLHSSSHTIK--SDAGAEEKKVP--------------------------------------SRKIRIGGSRLLQI-KGTRSFQ-------VKKGGSLSSIR-----RVGSLKSSKLSRQDSESEAEELQLSQSRDTVTDLEGSPWSASEPSIEPEGLSNAGTEENYHRNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLYGDSVDSLRESNHISNVA 1589 HSP 3 Score: 147.132 bits (370), Expect = 4.337e-34 Identity = 85/234 (36.32%), Postives = 133/234 (56.84%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN-----DR---------------ENKCSDG---ISYLHD-------------LSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C ++ DR EN+ S G S HD ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ ++QP+++ FTA VK
Sbjct: 4 RKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDCNNDQFGGTDRGSSWGGSSSAFIHQIENQGSPGQPCRSSSHDEEENNRRKTFQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEHRQPEVSGFTALVK 234 HSP 4 Score: 98.9821 bits (245), Expect = 1.624e-19 Identity = 65/198 (32.83%), Postives = 101/198 (51.01%), Query Frame = 1
Query: 3001 MSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQT-----HECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGR 3579
+SN+ +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ + + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+
Sbjct: 786 VSNHRLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRHQVFRENAQNCLTKLYKLDKIQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNKAGFG--NNFTTVDNKSTA----QNVEGIIVGAMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLAPGK 968 HSP 5 Score: 70.8626 bits (172), Expect = 4.400e-11 Identity = 45/160 (28.12%), Postives = 76/160 (47.50%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW FLDFIV R PIF+ L PF++ K+ PA E E + +Q I+ + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2862 AYLALKVILVCFERQLGSQWYWLSLQVKEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKL-----------------LAQPA-----ENHEELSARQHISDQLERRFIPRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2999 HSP 6 Score: 63.929 bits (154), Expect = 6.279e-9 Identity = 31/98 (31.63%), Postives = 61/98 (62.24%), Query Frame = 1
Query: 2362 QEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFE--KRIKKKKPDQENSSM 2649
EP+ L RS +D+ INY +E+ E + G+ +++ NG ++ +V+LKA++ ++N S RIC+ ++ + CL +G+ ++ +KK ++EN S+
Sbjct: 611 HEPLACANLPRSLTDSCINYSYLEDTEHIDGTNNFVHKNGMLDLSVVLKAVYLVLNHDISSRICDVALNIVECLLQLGVVPCVEKNRKKSENKENESV 708
BLAST of Protein unc-80 vs. Ensembl Mouse
Match: Unc80 (unc-80, NALCN activator [Source:MGI Symbol;Acc:MGI:2652882]) HSP 1 Score: 739.954 bits (1909), Expect = 0.000e+0 Identity = 450/1324 (33.99%), Postives = 725/1324 (54.76%), Query Frame = 1
Query: 6151 PATNKHKSSVK-EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF-QGENSNFYK-IKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQ--NSVVLEDQDESPY-----RLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
P+ K S V E +D +L Y+ V +L+ +++ K A +L E+++ DI P AWELLL D + +AA + +L A+K+P ++ E H + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + +C + + + ++++ K+F + +R Q+ E + K + EE++++ R+ +T I ++A +E + S+P +E N RRLS + + + RN S+R GS+ +S + V ED+++ + T QP Q VFP+ +CAA +PI+HL++DG+V DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P+ +H+ L ++L + PSFPR A+++EFSL+ GK+L+G+D L K W +L+ +F MPS FPW +I LFLN+FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VYS N L++AI F C QFYILHR PF+LQ+F S++ ++F N+ K + ++D+L+++ + D L+IL+L+ KPLK+LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ + + T + E A LA S++ L+ + + LTR P D+ N++ + N+ E + + LLEEG+ + DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ ++LI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + + + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1539 PSLKKRVSDVNLEGKKDSGMLKYIRFQVMSLSPAPLSLLIKAAPILTEEMYGDIQPAAWELLLSMDEHMAGAAAAMFLLCAVKVPDAVSDMLMSEFHHAETVQRLNAVLKFHTLWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPVLGMPSVPMFDPPW-VPQCSGSVQDPINEDQS-KSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPITQEACYEPTCTP-----------NSEPEEEEEVANLTSRRLSVS-PSCTSSTSHRNYSFRRGSV-WSVRSAVSAEDEEHATEHTPNHHVPQP---PQAVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELMYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPESQSTHYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMHPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPTAHKQSHVSMLQEDLLRLPSFPRSAIDAEFSLFSDPQAGKELFGLDTLQKSLWIQLLEEMFLGMPSEFPWGDEIMLFLNVFNGALILHPEDSALLRQYAATVINTAVHFNHLFSLSGYQWILPTMLQVYSDYESNPQLRRAIEFACHQFYILHRKPFVLQLFASVAPLLEFPDAANTGSSKGVSAQCLFDLLQSLEGETTDILDILELVKAEKPLKSLDFCYGNEDLTFSISEAIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKMKR----QTSQVETVPAAREEIAATAALATSLQALLYSVEVLTRPMTAPQMSRSDQGHKGTTTANHTMSSGVNTRYPEQGAKLHFIRENLHLLEEGQ----GLPREELDERISREEFR-----RPRESLLNICTEFYKHCGPRLKILQNLAGEPRVTALELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWSAEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASSLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVLLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRKEGLAESTSQAA 2794 HSP 2 Score: 146.747 bits (369), Expect = 5.102e-34 Identity = 85/234 (36.32%), Postives = 133/234 (56.84%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN-----DR---------------ENKCSDG---ISYLHD-------------LSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C ++ DR EN+ S G S HD ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ ++QP+++ FTA VK
Sbjct: 4 RKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDCNNDQFGGTDRGSSWGGSSSAFIHQIENQGSPGQPCRSSSHDEEENNRRKTFQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEHRQPEVSGFTALVK 234 HSP 3 Score: 142.124 bits (357), Expect = 1.354e-32 Identity = 88/207 (42.51%), Postives = 123/207 (59.42%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQ--FMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRT 4845
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S N N+K +Q A ++F+ W +A+G RL E + + + I DE R L+ DEEE+FLDDSTVNP CP+ALK QLLL ITT+LRET LP+ RT
Sbjct: 1171 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNITKKGLSRGRSPTVGNKRNQK---LQWSAAKLFYQWGDAIGIRLNELCHGESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSTVNPSKCGCPFALKMAACQLLLEITTFLRETFSCLPRPRT 1369 HSP 4 Score: 98.9821 bits (245), Expect = 1.646e-19 Identity = 65/198 (32.83%), Postives = 101/198 (51.01%), Query Frame = 1
Query: 3001 MSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQT-----HECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGR 3579
+SN+ +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ + + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+
Sbjct: 786 VSNHRLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRHQVFRENAQNCLTKLYKLDKIQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNKAGFG--NNFTTVDNKSTA----QNVEGIIVGAMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLAPGK 968 HSP 5 Score: 72.7886 bits (177), Expect = 1.208e-11 Identity = 34/114 (29.82%), Postives = 57/114 (50.00%), Query Frame = 1
Query: 5422 KESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
K+S S T ++ ++ SP S G+S +N+ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y + R+ + ++VA
Sbjct: 1408 KDSLHSSSHTIKSDAGAEEKKEGSPWSASEPSIEPEGLSNAGTEENYHRNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLYGDSVDSLRESNHISNVA 1521 HSP 6 Score: 70.8626 bits (172), Expect = 4.391e-11 Identity = 45/160 (28.12%), Postives = 76/160 (47.50%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW FLDFIV R PIF+ L PF++ K+ PA E E + +Q I+ + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2794 AYLALKVILVCFERQLGSQWYWLSLQVKEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKL-----------------LAQPA-----ENHEELSARQHISDQLERRFIPRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2931 HSP 7 Score: 63.929 bits (154), Expect = 6.010e-9 Identity = 31/98 (31.63%), Postives = 61/98 (62.24%), Query Frame = 1
Query: 2362 QEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFE--KRIKKKKPDQENSSM 2649
EP+ L RS +D+ INY +E+ E + G+ +++ NG ++ +V+LKA++ ++N S RIC+ ++ + CL +G+ ++ +KK ++EN S+
Sbjct: 611 HEPLACANLPRSLTDSCINYSYLEDTEHIDGTNNFVHKNGMLDLSVVLKAVYLVLNHDISSRICDVALNIVECLLQLGVVPCVEKNRKKSENKENESV 708
BLAST of Protein unc-80 vs. Ensembl Mouse
Match: Unc80 (unc-80, NALCN activator [Source:MGI Symbol;Acc:MGI:2652882]) HSP 1 Score: 146.362 bits (368), Expect = 1.166e-37 Identity = 85/234 (36.32%), Postives = 133/234 (56.84%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN-----DR---------------ENKCSDG---ISYLHD-------------LSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C ++ DR EN+ S G S HD ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ ++QP+++ FTA VK
Sbjct: 4 RKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDCNNDQFGGTDRGSSWGGSSSAFIHQIENQGSPGQPCRSSSHDEEENNRRKTFQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEHRQPEVSGFTALVK 234
BLAST of Protein unc-80 vs. UniProt/SwissProt
Match: sp|Q8N2C7|UNC80_HUMAN (Protein unc-80 homolog OS=Homo sapiens OX=9606 GN=UNC80 PE=1 SV=2) HSP 1 Score: 741.495 bits (1913), Expect = 0.000e+0 Identity = 447/1313 (34.04%), Postives = 719/1313 (54.76%), Query Frame = 1
Query: 6184 EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF--QGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESP--------YRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
E +D +L Y+ V +L+ +++ K A +L E+++ DI P AWELLL D + +AA + +L A+K+P ++ E H + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + +C + + + ++++ K+F + +R Q+ E + K + EE++++ R+ +T I ++A +E + + E ++E N A RRLS + + + RN S+R GS+ +S + V ED+++ + T QP Q VFP+ +CAA +PI+HL++DG+V DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P+ +H+ L ++L + PSFPR A+++EFSL+ GK+L+G+D L K W +L+ +F MPS FPW +I LFLN+FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VYS N L++AI F C QFYILHR PF+LQ+F S++ ++F N + ++D+L+++ + D L+IL+L+ KPLK+LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ L + T + E A LA S++ L+ + + LTR P D+ N++ + + V Q++ LLEEG+ + DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ +NLI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + + + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1550 EGKKDSGMLKYIRLQVMSLSPAPLSLLIKAAPILTEEMYGDIQPAAWELLLSMDEHMAGAAAAMFLLCAVKVPEAVSDMLMSEFHHPETVQRLNAVLKFHTLWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPVLGMPSVPMFDPPW-VPQCSGSVQDPINEDQS-KSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPITQEACYEPTCTPNSEPEEE----------VEEVTNLASRRLSVS-PSCTSSTSHRNYSFRRGSV-WSVRSAVSAEDEEHTTEHTPNHHVPQP---PQAVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELMYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPESQSTHYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMHPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPTAHKQSHVSMLQEDLLRLPSFPRSAIDAEFSLFSDPQAGKELFGLDTLQKSLWIQLLEEMFLGMPSEFPWGDEIMLFLNVFNGALILHPEDSALLRQYAATVINTAVHFNHLFSLSGYQWILPTMLQVYSDYESNPQLRQAIEFACHQFYILHRKPFVLQLFASVAPLLEFPDAANNGPSKGVSAQCLFDLLQSLEGETTDILDILELVKAEKPLKSLDFCYGNEDLTFSISEAIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKR----QTSQVETVPAAREEIAATAALATSLQALLYSVEVLTRPMTAPQMSRCDQGHKGTTTANHTMS-SGVNTRYQEQGAKLHFIRENLHLLEEGQ----GIPREELDERIAREEFR-----RPRESLLNICTEFYKHCGPRLKILQNLAGEPRVIALELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWTAEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASNLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVLLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRREGLAESTSQAA 2794 HSP 2 Score: 144.436 bits (363), Expect = 1.862e-32 Identity = 82/235 (34.89%), Postives = 131/235 (55.74%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDR---------------------ENKCSDGIS----------------YLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C +N+R EN+ S G + + ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ ++QP ++ FTA VK
Sbjct: 4 RKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDC-NNERFGGTDRGSSWGGSSSAFIHQVENQGSPGQPCQSSSNDEEENNRRKIFQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEHRQPGVSGFTALVK 234 HSP 3 Score: 142.895 bits (359), Expect = 5.774e-32 Identity = 88/207 (42.51%), Postives = 124/207 (59.90%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFM--NNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRT 4845
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + N N+K +Q A ++F+ W +A+G RL E + + + I DE R L+ DEEE+FLDDSTVNP CP+ALK QLLL ITT+LRET LP+ RT
Sbjct: 1170 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNITKKGLSRGRSPIVGNKRNQK---LQWNAAKLFYQWGDAIGVRLNELCHGESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSTVNPSKCGCPFALKMAACQLLLEITTFLRETFSCLPRPRT 1368 HSP 4 Score: 99.7525 bits (247), Expect = 6.403e-19 Identity = 67/205 (32.68%), Postives = 105/205 (51.22%), Query Frame = 1
Query: 2980 EELNSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQT-----HECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGR 3579
E+ S +SN+ +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ ++ + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+
Sbjct: 776 EKDESTPVSNHRLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRHQVFRENAQNCLTKLYKLDKMQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNKAGFG--NNFTTVDNKSTA----QNVEGIIVSAMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLAPGK 965 HSP 5 Score: 73.559 bits (179), Expect = 5.026e-11 Identity = 35/114 (30.70%), Postives = 56/114 (49.12%), Query Frame = 1
Query: 5422 KESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
K+S S T ++ ++ SP S G+S +N+ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y + R+ +SVA
Sbjct: 1407 KDSLHSSSHTLKSDAGVEEKKEGSPWSASEPSIEPEGMSNAGAEENYHRNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLYGDSVDSLRESSNISSVA 1520 HSP 6 Score: 70.4774 bits (171), Expect = 5.078e-10 Identity = 45/160 (28.12%), Postives = 75/160 (46.88%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW FLDFIV R PIF+ L PF++ K+ PA E E + +Q I + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2794 AYLALKVILVCFERQLGSQWYWLSLQVKEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKL-----------------LAQPA-----ENHEELSARQHIADQLERRFIPRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2931 HSP 7 Score: 63.929 bits (154), Expect = 4.688e-8 Identity = 35/119 (29.41%), Postives = 71/119 (59.66%), Query Frame = 1
Query: 2302 FFDDSPKQEKLSNEQQL-QRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFE--KRIKKKKPDQENSSM 2649
FF++ KL N+ + + EP+ L RS +D+ INY +E+ E + G+ +++ NG ++ +V+LKA++ ++N S RIC+ ++ + CL +G+ ++ +KK ++EN ++
Sbjct: 591 FFNE--HMRKLCNQVPIPEMPHEPLACANLPRSLTDSCINYSYLEDTEHIDGTNNFVHKNGMLDLSVVLKAVYLVLNHDISSRICDVALNIVECLLQLGVVPCVEKNRKKSENKENETL 707
BLAST of Protein unc-80 vs. UniProt/SwissProt
Match: sp|Q8BLN6|UNC80_MOUSE (Protein unc-80 homolog OS=Mus musculus OX=10090 GN=Unc80 PE=1 SV=2) HSP 1 Score: 739.954 bits (1909), Expect = 0.000e+0 Identity = 449/1324 (33.91%), Postives = 725/1324 (54.76%), Query Frame = 1
Query: 6151 PATNKHKSSVK-EKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF-QGENSNFYK-IKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQ--NSVVLEDQDESPY-----RLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQAS 10047
P+ K S V E +D +L Y+ V +L+ +++ K A +L E+++ DI P AWELLL D + +AA + +L A+K+P ++ E H + QR++A+L+F +LW R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + +C + + + ++++ K+F + +R Q+ E + K + EE++++ R+ +T I ++A +E + + E +E+ N RRLS + + + RN S+R GS+ +S + V ED+++ + T QP Q VFP+ +CAA +PI+HL++DG+V DGVAV+ +A+ V+W CL+ED + LR+ LE+LT +DEL+Y+LRKL+ + + P Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F K E+G+V+F S+ + P+ +H+ L ++L + PSFPR A+++EFSL+ GK+L+G+D L K W +L+ +F MPS FPW +I LFLN+FNG LILH ED+A+LR A I + HF +FS++GY I+PT+L+VYS N L++AI F C QFYILHR PF+LQ+F S++ ++F N+ K + ++D+L+++ + D L+IL+L+ KPLK+LDFCY NE+ ++S+ EA+ LCVTV+ YAP+S R+ QM+++L+A++P L+ + + T + E A LA S++ L+ + + LTR P D+ N++ + N+ E + + LLEEG+ + DE P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R+++E+ P DW E+++ AL ++ RL+R NKI K RR ++W+ ++LI+ V L ++R ++F+ +R L+ L++ P ++ + L + S Y P FS V++ AL +Q+L+ + L F T + + N++IP +L G+G KDS + + + +++ L P II + N+ P H P G +G + +QA+
Sbjct: 1541 PSLKKRVSDVNLEGKKDSGMLKYIRFQVMSLSPAPLSLLIKAAPILTEEMYGDIQPAAWELLLSMDEHMAGAAAAMFLLCAVKVPDAVSDMLMSEFHHAETVQRLNAVLKFHTLWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPVLGMPSVPMFDPPW-VPQCSGSVQDPINEDQS-KSFSARAVSRSHQRAEHILKNLQQEEEKKRLGREASLITAIPITQEACYEPTCTPNSEPEEEVEEVA----------NLTSRRLSVS-PSCTSSTSHRNYSFRRGSV-WSVRSAVSAEDEEHATEHTPNHHVPQP---PQAVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPSTVLRHFLEKLTISNRQDELMYMLRKLLLNIGDFPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPESQSTHYFLMDKRWNLIHYNKTYVRDIYPFRRSVSPQLNLVHMHPEKGQELIQKQVFTRKLEEVGRVLFLISLTQKIPTAHKQSHVSMLQEDLLRLPSFPRSAIDAEFSLFSDPQAGKELFGLDTLQKSLWIQLLEEMFLGMPSEFPWGDEIMLFLNVFNGALILHPEDSALLRQYAATVINTAVHFNHLFSLSGYQWILPTMLQVYSDYESNPQLRRAIEFACHQFYILHRKPFVLQLFASVAPLLEFPDAANTGSSKGVSAQCLFDLLQSLEGETTDILDILELVKAEKPLKSLDFCYGNEDLTFSISEAIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKMKR----QTSQVETVPAAREEIAATAALATSLQALLYSVEVLTRPMTAPQMSRSDQGHKGTTTANHTMSSGVNTRYPEQGAKLHFIRENLHLLEEGQ----GLPREELDERISREEFR-----RPRESLLNICTEFYKHCGPRLKILQNLAGEPRVTALELLDVKSHMRLAEIAHSLLKLAPYDTQTMESRGLRRYIMEMLPITDWSAEAVR--PALILILKRLDRMFNKIHKMPTLRRQVEWEPASSLIEGVCLTLQRQPIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVALQIQALKEDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPWLEQPEVQLLLQTVINVLLPPRIISTSRSKNFMLESSPAHCSTPGDAGKDLRKEGLAESTSQAA 2797 HSP 2 Score: 147.132 bits (370), Expect = 3.095e-33 Identity = 85/234 (36.32%), Postives = 133/234 (56.84%), Query Frame = 1
Query: 70 KPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN-----DR---------------ENKCSDG---ISYLHD-------------LSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
+ S E + IPL IQ+FL QT++F K + + +C+S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC + L+ R K + K+ + ETK++++LHW++++A +C ++ DR EN+ S G S HD ++ ++LFV+LFAPLV +I ES T +L +GL IW P+ ++QP+++ FTA VK
Sbjct: 4 RKSSEGQEQDGGRGIPLPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSPALSEAIQSISRWELVQAALPHVLHCTATLLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAPQDCNNDQFGGTDRGSSWGGSSSAFIHQIENQGSPGQPCRSSSHDEEENNRRKTFQNSMATVELFVFLFAPLVHRIKESDL-TFRLASGLVIWQPMWEHRQPEVSGFTALVK 234 HSP 3 Score: 142.124 bits (357), Expect = 9.472e-32 Identity = 88/207 (42.51%), Postives = 123/207 (59.42%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQ--FMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRT 4845
K + ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S N N+K +Q A ++F+ W +A+G RL E + + + I DE R L+ DEEE+FLDDSTVNP CP+ALK QLLL ITT+LRET LP+ RT
Sbjct: 1173 KSKNVVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARAALFLECARFVHRCNRGNWPEWMK----GHHVNITKKGLSRGRSPTVGNKRNQK---LQWSAAKLFYQWGDAIGIRLNELCHGESESPA-NLLGLIYDEETKRRLRKEDEEEDFLDDSTVNPSKCGCPFALKMAACQLLLEITTFLRETFSCLPRPRT 1371 HSP 4 Score: 98.9821 bits (245), Expect = 1.151e-18 Identity = 65/198 (32.83%), Postives = 101/198 (51.01%), Query Frame = 1
Query: 3001 MSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQT-----HECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGR 3579
+SN+ +A+ ++IK++K LGC Y C + G + + R Q CL KLYK+ +F+ + SL+++V+FLHA GFC +P + AG NN+ N+S + EG+ + + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L K G+
Sbjct: 786 VSNHRLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRHQVFRENAQNCLTKLYKLDKIQFRQTMRDYVNKDSLNNVVDFLHALLGFCMEPVTDNKAGFG--NNFTTVDNKSTA----QNVEGIIVGAMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKEAHGNVFRRVALSALLDSAEKLAPGK 968 HSP 5 Score: 72.7886 bits (177), Expect = 8.522e-11 Identity = 34/114 (29.82%), Postives = 57/114 (50.00%), Query Frame = 1
Query: 5422 KESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
K+S S T ++ ++ SP S G+S +N+ +M W+ V+ N+ +F+C HVD+CHP CY R C RL+ A+K +Y + R+ + ++VA
Sbjct: 1410 KDSLHSSSHTIKSDAGAEEKKEGSPWSASEPSIEPEGLSNAGTEENYHRNMSWLHVMILLCNQQSFICTHVDYCHPHCYLHHSRSCARLVRAIKLLYGDSVDSLRESNHISNVA 1523 HSP 6 Score: 70.8626 bits (172), Expect = 3.177e-10 Identity = 45/160 (28.12%), Postives = 76/160 (47.50%), Query Frame = 1
Query: 10246 SFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
++LALKV ++C+ R Q +S + ++ +K GG+ LW FLDFIV R PIF+ L PF++ K+ PA E E + +Q I+ + +P P C+++++ E +L+ +K+ S Y + V + AY
Sbjct: 2797 AYLALKVILVCFERQLGSQWYWLSLQVKEMALRKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKL-----------------LAQPA-----ENHEELSARQHISDQLERRFIPRPLCKSSLIAEFNSELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2934 HSP 7 Score: 63.929 bits (154), Expect = 4.204e-8 Identity = 31/98 (31.63%), Postives = 61/98 (62.24%), Query Frame = 1
Query: 2362 QEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFE--KRIKKKKPDQENSSM 2649
EP+ L RS +D+ INY +E+ E + G+ +++ NG ++ +V+LKA++ ++N S RIC+ ++ + CL +G+ ++ +KK ++EN S+
Sbjct: 611 HEPLACANLPRSLTDSCINYSYLEDTEHIDGTNNFVHKNGMLDLSVVLKAVYLVLNHDISSRICDVALNIVECLLQLGVVPCVEKNRKKSENKENESV 708
BLAST of Protein unc-80 vs. UniProt/SwissProt
Match: sp|Q9VB11|UNC80_DROME (Protein unc-80 homolog OS=Drosophila melanogaster OX=7227 GN=unc80 PE=1 SV=5) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 487/1503 (32.40%), Postives = 766/1503 (50.96%), Query Frame = 1
Query: 5980 RSRRK--ESMFGNHSPHRRKDSVPLFDKFLKSRTXXXXXXXXXSSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSA-STQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVF---DEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQ--GENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQN-SVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKH----KALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXX-XXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVS 10446
RS RK E SP +RKDS+ D+ SD+ L + EK A + K K+ E+ PIL ++ ++ NL H + KGA++L E++ + MP AWELLLE + + S+A V ++ ++K A ++ R L+H+D + R+ A+ R+ LW CRF W R+E++A K+PP IEF LPSP +G V DP W + +V L Q+ ++ VTA+ +R+ QQ E + A+ + +++ R F +T + S++ E G+E +L I E+D +G+ ++S L +A +FPS LC++ + I+ LDD + SDG AV IA V+W CLVE++ LFLRY+ ERLTR +D++ +LR LI+ +P LP Q+A AL+N+++GYIMFYVR+ + E + ALS+LW +V V I FKDLKQILRKEQ D ++++TAN+P AK+ V D+D + +Q++T F ++LKEAL I E++ Y L D +S+ I N + Y+RD YFFKR+ P++RL M PE+ LQ+ KF+EIGKV +++ILK+ + + FLH+EL K PSFPRKALE + L+ G GK L G+D+LHK W RL++ +FE M +F +++DI LFLN+ +G ILHAED+ ++R +A I A+ +FK IFS NGY IMPT+L+VYS + N ++ I + KQFY+L+R PFILQMFGS+S +D G +K++ ++++L ++ D LNI +L+ KPLKA+DFCY +E+D +VL+ +TLCV V+ Y+ +S R QM+IIL+AILP L+ QI P +S R I I QLAV+++ ++ C+ L + + P+ + K S + N S+ S L+ ++E+ + + + R KN + S E R P + +L V DF T RL E+ +K K E+LD K +RL+++A S++K+ P D + + LQR+M + P +W ++++++ AL ++ R+++ KI K RRN DW++ L+K + + R+ V + ++ L+ ++ LI+ ++ P V++ G A P F + V++ AL + S + L C + F T E + I+ L +C G G D ++ ++ F+ +L N + P A G G R TG+ G + G S +P + + LY+ +FLAL++ IC+ + I V+ DLG + + LW F++F+VT RTP+++ L+PF+ K+S
Sbjct: 1643 RSTRKVSEQSSTQTSPSKRKDSLSRKDRI---------------SDDPDL--EMAEKLAKAFRQEKE--KKMQEEPPILKFIRIHIRNLFHFPLATLLKGAVVLTEEMVIEAMPAAWELLLETNHDTATSSAAVFLMGSVKAQNFAFDIMQRALKHKDPDIRIGAIQRYLVLWKCRFHVWPRMEENAHDVTFKVPPGGIEFTLPSPKIGIESLPVVDPPWMPVQQTKDMDVTLNQDRH-RSLVTATKSRKMQQTEAIRNALRQQRDKQRAERHSFLITM----------IPISQQASHEPGME------------------KLEDHEI----------------------------EEDLDGTRMSSH------LHHAHSLFPSVLCSSVMQIVGCLDDAAIGSDGNAVYEIAYQVIWVCLVEESALFLRYVFERLTR-DRQDQMFKLLRHLIRFVPRLPQQAAFALYNSIIGYIMFYVRSSNELKQELVGSALSVLWMVVHSVHGIMFKDLKQILRKEQCDASILLTANVPAAKKIVVHGPADDDYNIPSQFPVQEDT---LFCQLLKEALDYYPIDEKNTSHYCLVDYKSSKILNPNWYIRDLYFFKRSQYPEVRLMLMRPEESFLALQKQELTKKFVEIGKVHLTWAILKNV--DMVVQRVVFLHEELMKLPSFPRKALEVDLDLHHGGEYGKVLLGLDVLHKFMWVRLIARMFEAMAGNFAYSADIQLFLNVLSGASILHAEDSCIMRYVMATFINAAFNFKNIFSTNGYFMIMPTLLQVYSLHQTNKLITTTIEYAVKQFYLLNRKPFILQMFGSVSAILDTDEDGTYGEAHKVQSSCLFNLLLSLEDPSPDPLNIAELVKEPKPLKAIDFCYHDEDDDVTVLDCITLCVMVVSYSAESTRGYQMLIILEAILPCYLQ---QIQSPSYIPLQGKSERDI----ILQLAVAIRTMVHNCEGLAKSYNGPYRNSPEHKGSSQ--RNCSRGPPCSPGLDFEEETHPKYMTDAR-TKNMMDSAEDSEMIRTEYRR------PRDVLLSVVADFLTKSTVRLAELAKKMPSDTKPTEVLDAKCHIRLADIAHSLLKVSPYDPESMACRGLQRYMQAVLPRAEWSNDTLRN--ALVTILRRIDKVFLKISKKPSIRRNTDWEAAAGLLKGIHETIIRHSYVLHWQQMKTLISTVQNLIV--------------------NEPGIPEGVSSAG-------AALMSQNPPAFFCSAVVRLVALQVVSPVDCFSLVQICGGSSE-FATQEKAEGFLMHLIMPLCLKVCSGRGVSDVGELKMSDVSFLLTAVL----------------------NAMSPPA---GRTGQAVSQINRV--------TGDLRAGSLTFTG-SRDAKRPARI------------------------SGSLYQAAFLALRIVCICFESRLSNEWPRIVRVMRDLGRRNEAAPDLWSFMEFVVTHRTPLYIVLLPFILHKIS 2953 HSP 2 Score: 216.083 bits (549), Expect = 3.590e-54 Identity = 162/506 (32.02%), Postives = 251/506 (49.60%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDL-ESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSA-IPMSGDHQFMNNTN-KKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPK-SRTISLKEPI-YETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESI-VGEIGQINTEIHPAPGNRRISFAF------SLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
K+RK + ++ GM SF+L++ PG P+PQLVA++LDL ++P++ARA LLE A+FV CNKG+WP+WM+ GSY S A I ++ Q ++ T+ ++ +QR AG+MFH WAE +GARLE L E+ N S + D K REL DEEE+FLD+++VNP G+ CP++LK + LL IT +LR+T+ LPK S+ I +P +E Y + + + + + TS S++SI G G +E R+ISF S +SSN +L + G +AR+ P TSA+ F+ T ++T GS +RR L+ RR + + T S ++ S+ R ++S+ + + ES + P + +E D+ + +MPW++ + + N+ C H +CHP CY+R R C RL+ A + VY
Sbjct: 1179 KERKLVPTEPVRVGMLRLSFLLETCAPGSFPDPQLVAAVLDLPQAPLVARATFLLECAHFVHLCNKGQWPAWMKQNV-GSYRASGANINLNQMKQQVSQTSARRTHILQRAAGKMFHQWAEMVGARLEEILFTERLQYEAVNAS-LTDPEKQRELLQQDEEEDFLDETSVNPHGNDCPHSLKLIACVLLFEITAFLRDTYLMLPKTSKLIHRDKPAPWEKVYREANRRWSMALSSMGHSQTS---------------AQSLQSIAAGNDGAGQSE-------RKISFVLHEPDNESENSSNTTLTK---EGEEARR-PTTSAVRPFL------LRRGTATTTG----------GSFKRRS-------LKLRRNTKDSKDIET-----------DFNMQSRRKVSSLSDRSDTSEQGMISGGEESPGILSDDQQPESP----------TDSNENDDTAKNMPWLKAIIDLMSSYNYYCTHKGYCHPFCYKRHMRSCTRLVKATRKVY 1612 HSP 3 Score: 143.28 bits (360), Expect = 3.874e-32 Identity = 78/213 (36.62%), Postives = 114/213 (53.52%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFF------LNKNT------------RDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMH-CASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDND----------RENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCR 663
+P+ +Q+FL Q F L+++T AC S E+VLVQNI GLSP + + ++ RW+ ++ A PHVMH CA+LL ++ P ETK++Y++ WI++ AA EC D++ E K YL + I LFVYLFAP++ + ES FQ +LENG+ +W + + + P CFTAPVK K R
Sbjct: 53 LPVSVQTFLWRQIAPFIRPKLGKLHESTCLFCQHAPGHHESKEACKSFEKVLVQNIQFGLSPPLTKGLGVIPRWRLLQGALPHVMHACAALLYNRVKDMQAIGP---VETKLLYTMQWILLYAAEECADDEGGEDLGLGDAAEPKSKSIDQYLFSVPTITLFVYLFAPIIHHLKESDFQNFRLENGIKLWQGMWDNRAPGAPCFTAPVKPKAR 262 HSP 4 Score: 97.8265 bits (242), Expect = 2.145e-18 Identity = 79/277 (28.52%), Postives = 130/277 (46.93%), Query Frame = 1
Query: 2998 GMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVW-RKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDL---HNRTSSLSAALVATELLQQMAANNQNYKPGKKNI--FKRYSSAV 3810
G ++I+M I + +++LGC H C + + G + R Q + L ++ + ++ + F+ M + L +++++ HA+ FC DP+SL S+ Y F+ ++G +E + +PLV R V + KDL EN LY DIRQL+ Y K HG FR V L+G+L V R K+G + + I + S D+ RS L TSS A+L+ TE A ++YK + + F+R ++ V
Sbjct: 792 GEHAHEISMSITRRALQVLGC--PHGCNDGVR-------GPPADFLRNQCQKILSRMLRQAGQRTKRFMQEMVKTSPLPELIDYFHAFLAFCVDPSSL--LSPLSQGGYSTNFSGGMSGG----AEAQVVGAVFKPLVSRFVEASKDLKGPENIALYGDIRQLVTYVKGAHGGPFRLVALSGILAVTPRPHKKGPSAQTTRVIRHIPQANANQSLQNDD----NRSQRRLLLKKRSTSSACASLLETE------ACEEHYKTSQSPLSNFRRRTTGV 1043 HSP 5 Score: 57.3806 bits (137), Expect = 3.632e-6 Identity = 48/169 (28.40%), Postives = 74/169 (43.79%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLXXXXXXXXXXXXXXXXTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSS 1773
D A+ LD+AVLRCLF W E G++W L+YL+ RL +I E ++ Q + KRS S + EI S +Q P G DS + + + DP ++A + + K++KM D + F + F K+E + D +S
Sbjct: 425 DVSAATFLDVAVLRCLFISHWQEEGIFWSLQYLYNRLSDIGEEAAITLNQPR-------KRSNSLPIPQIEI--SLYQGP--GSNSRDSPGSSVVKDY----IEIPDPSPTVTACVAEEPQSAPSTTERRGSEKKKRVKMADLRA-FVETKMFSKSEKNLEKVGLDTNS 577
BLAST of Protein unc-80 vs. UniProt/SwissProt
Match: sp|Q9XV66|UNC80_CAEEL (Protein unc-80 OS=Caenorhabditis elegans OX=6239 GN=unc-80 PE=2 SV=4) HSP 1 Score: 510.375 bits (1313), Expect = 1.815e-143 Identity = 292/844 (34.60%), Postives = 483/844 (57.23%), Query Frame = 1
Query: 7093 LQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEK------------DELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHII-----YDILRAIS--TDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVL-EAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVG--DEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMG------EKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLD 9540
+ AQ +FPS+L + II LLDD V+++GV+V +A+ V+W C+VED +LFLR+ LE+LT + + L+ LRKL+ R LP+Q+AH+L N L G++M YVR + ++I ALS+ W + P + +YFKDLKQ L+KEQ D LM+TAN+P AK+ V D + +D +F +IL ++L+ NI E D + + L D ++ +I + YVRD+YFF R+ P+L L K++PE ++ AF+ KF+E GKV+ +++ILK++P + ++FLHDE T PSFPRK+LE+ F +Y G G+QL M+ +HK W +++S +FE+M ++F + +D+HLF+N+ NG++I+H ED +LR C A I S HF +F+ G+ IMPT+LR YS+ N V + F+C+QFY LHR PF+LQM G+I+N ID +SN ++I P + +++++ + TD ED L+IL L+ KPLKALD CY ++ +++ L +A+ C+ V ++P+S R+ M++I+QA+LP +++ L + + + N+ + K E +AV +K LI +C+ L R + F V E+ V + ED++ PY L E +++T V+ E + P + +LQ+ + RL E+ E K ++LD K ++L E+A +++K+ P D++ LQ++ I P DW ES +S AL ++ RL+++++KI K R+ W ++++ I + + +A + +R + + ++++ D
Sbjct: 1962 MPVAQPLFPSALLSVVPQIIELLDDPQVDNNGVSVGDVAKKVIWTCIVEDPSLFLRHFLEKLTNRDRQVLISEYAPTPAYEALMSQLRKLVLRFHPLPSQAAHSLLNYLFGFVMHYVRAQCEGSEKAIGMALSICWLLSPNIHGLYFKDLKQTLKKEQCDQALMITANVPSAKKIIVHGLDSTSGGIPSQFPVHEDTQFHQILNDSLEFFNIDEDDLNCFYLTDTKTGVIHLPAAYVRDYYFFHRSFYPQLTLVKLSPEVAEKKMKETAFHQKFIECGKVLLTHNILKYSPQHVIAQRVFFLHDEFTHLPSFPRKSLETCFGMY-FGPGGEQLKAMESMHKFVWAKMMSDMFEKMENAFMF-ADLHLFINVINGIMIMHCEDVLILRRCAATYISISIHFNTLFASQGFFLIMPTLLRCYSQRQTNKVFCGVVEFICRQFYTLHRKPFLLQMCGAIANIID---NSSNDFEINPMRVKAKYWFNLIKKMEEITD-EDPLDILGLVPYEKPLKALDLCYRDDPNTFCALTDAMASCICVCAFSPESKRSHHMLLIMQAMLPHMMKRLEEETLQ---SGNSPAAVKHEISQWITMAVEMKALINSCEQLVRGPTRAFDLVNSVSERGKSFVADSPQFFDPPTTNEDENSRPYHLKE----KRSTAVAWEAAEVEEQQKE---TYRRPRDTLLQLIAAYIEMASVRLKELTKLGANLEHAKIPDVLDHKCYVKLGEVALALLKVAPYDLSTTTCHGLQKYFQIILPVTDWSIESNRS--ALNIILRRLDKTLSKIAKRQSFRKRAIWIALSSWINGICDTLNAFPYIAHLHPLRTITQLCLRMMVGD 2787 HSP 2 Score: 164.851 bits (416), Expect = 1.384e-38 Identity = 83/216 (38.43%), Postives = 136/216 (62.96%), Query Frame = 1
Query: 112 IPLQIQSFLLTQTNSFFLNK--NTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN----DRENKCSDGISYLHDLSAIQLFVYLFAPLVDQI-DESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVA--SNSRATDGIGVKSAQIYIGK 732
+PL IQ+FL QTN F +K + +C++ ERV+VQNI+HGLSP++ +A+ VSRW+ ++ A PHV+ C L+ E K+P ++ KI+Y LHW+++D+++EC +N D + C L ++S+IQLF+YL APL D I +E + ++LE+GL +W + ++QPD+ CF+APVK + + + +R + + + IY+GK
Sbjct: 44 VPLPIQTFLWRQTNPFLGDKIGKLHEASCVTFERVVVQNILHGLSPSLSNALASVSRWKLVRAALPHVIQCCGSLLLANVG-EKKLP--TSLQKILYILHWMLIDSSSECIENASTKDDRSVCQSRTQGLFNISSIQLFIYLIAPLADVISEEEVVDNIRLESGLKVWQAIWQFRQPDVWCFSAPVKQRRDELPQITFARRQNPAQLDTQGIYLGK 256 HSP 3 Score: 155.992 bits (393), Expect = 6.147e-36 Identity = 85/236 (36.02%), Postives = 133/236 (56.36%), Query Frame = 1
Query: 6193 EDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAA--KTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQ 6894
++ P+L YL + V L H+ + V K LLL+ + ++ V W++L+ DP +VASAA++ I+A++K + +I L +D R S + RF +LW RF W ++ED A K+PPP I+F LPSP +G V DP W EE+ LK+ E A +T +T + TRRKQ+QEM+++AV E+R+ RQ F L + +I+ A++E A +++ D Q
Sbjct: 1721 KNKPMLTYLRSLVLQLVHSPISSVLKCCLLLSVEQHKQMIEVCWKMLIHEDPHVVASAASMFIVASVKKSEESLLIIKTALDSQDPQVRTSGIQRFYTLWRNRFHAWLKMEDGAQASFKVPPPGIDFTLPSPAIGQSQLPVVDPPWMPHLKTKIEELSLKEEEHATSQTIMTMTRTRRKQKQEMVKRAVREAEERQSEQRQLFRLRSSAIVSLAAYEPALFHHQQEQTEESDNSHQ 1956 HSP 4 Score: 140.198 bits (352), Expect = 4.007e-31 Identity = 97/303 (32.01%), Postives = 148/303 (48.84%), Query Frame = 1
Query: 4243 FIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPK-GDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISF-AFSLHSSNNSLDQTDESGSKARKA 5145
+ID + G F+F+L++ PG P+ L+A+++ L+SPVLARA LLLE AN V+RCN+G+WP W+R ++ A+ G + +++ +QRQAG+ F+ W +G + S + E+ + + LQ+ D E+F DD VN + G+ CP AL+ + + LL IT +LRET + +P+S+ +P S D H+R I T + Q G V I +IN+ IH RRISF A S S D DE + +K
Sbjct: 1098 YIDAKGIFDGARRFAFLLETARPGTFPDAPLIAAIMHLKSPVLARASLLLECANLVSRCNRGQWPEWIRSSHHRTFSLGGALANRG----TPSATRRMHSLQRQAGRYFYQWGVQIG-------------EHISKLLELSENKSKKTLQMEDTIEDFFDDGIVNNQNGEKCPIALQFIAVLLLQEITAFLRETFKTIPRSKN---SKPQTGNS-GWDKLLSHRR-WSILSNTFNAQQTGS----------------VNSITEINSSIHLNDKERRISFSATEEDSPRGSKDAIDEINAVDKKG 1362 HSP 5 Score: 62.7734 bits (151), Expect = 9.967e-8 Identity = 25/77 (32.47%), Postives = 46/77 (59.74%), Query Frame = 1
Query: 5545 SELDNFSSHM----PWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVA 5763
S +D+ HM PW++V+ +F+N + CNHV C C++R RQC R++ ++ T+Y + + + D++N +A
Sbjct: 1547 SSMDDEEQHMLSNLPWIKVLIKFSNSFDLECNHVGVCSAKCFQRVHRQCFRMIESLSTLYGMERNVSTRADKRNLLA 1623 HSP 6 Score: 57.3806 bits (137), Expect = 4.400e-6 Identity = 25/79 (31.65%), Postives = 43/79 (54.43%), Query Frame = 1
Query: 1267 DFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQE 1503
D +AS+LD+AV+R L W E GVYW L Y+H RL+EI + + + +R N+ + + ++++ W +
Sbjct: 531 DPTIASYLDVAVIRALLITHWQEKGVYWALSYIHNRLIEIKAYMIIRKSTRQR-SNSLPSGERKLSVAPEQLTNPVWDD 608
BLAST of Protein unc-80 vs. TrEMBL
Match: A0A4V3SF12 (UNC80 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005205 PE=4 SV=1) HSP 1 Score: 1256.12 bits (3249), Expect = 0.000e+0 Identity = 688/1442 (47.71%), Postives = 941/1442 (65.26%), Query Frame = 1
Query: 6202 PILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGG-----------SQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHE--------DDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYI----DFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTD--------KPFGKVG--DEKCSFRVGGNYS-QTQNSVVLEDQDESPYRLLEEGRFRKNTV--VSNNCDEPSGGNSRHIVSAIA------PHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSS------------PY------------AMNESLSSIQFSGRHDQTSPNHVTATGG--------DNTYSQATH-TYNG---IPP------------------KFSAMVIKFFALMLQSLESTYKLKDFCERFDQRF---------GTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTG----TQASTRFLTSTAAAN------TGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIR 10182
PI Y+ + V N+ N FN++NK ALLL + ++P+AWELLLE + ELV+S A ++ ++ +L Q+L+ E+QH +QR+SA+LRFR+LW R W RL++ AS QL+LPP +IEFVLPSPTLG+ G D PDP W IRK SAEEVQLKQNEA KTFVTAST+RRKQQQE+L +A+ AE RR+ AR++FHLTTC +LE+A+ E AF+KEH+DE +++G PIQEEF AAV+RLS A +NR + VQ+R+ SWR GSIP+ R++ + H+ DD S + P+ QPLQ AQ +FPS+LCAA++P+IHLLDD VN DG+AV+TIAEH ++QCLVEDT LFLR+I ERLTR K EL++ LRK+IQRLPELP QSAH +FNNLVGYIMF+VRTP+ +APE+IA ALS+L +VP VQNIYFKDLKQ LR+EQ+D TL++TANLPCAKQFNVFD D+ VAQLVRL DE KDY+F +ILK+AL+ S IP + Y LCDDRS II N+SHY+RDFY FKRNH PKLR+K+M DG HLLQ+NA NLKF EIGKV+F+ ++L+ TPS Q +NH++FLH+ELTK PSFPRKALESEF LY LG+ L G+D +HKISWC L+S LFERMP+++PW++D+ LFLN++NG LIL AED+++LR CLA IQ S FKM FS +GY GI+PT+LRVY++ HN VL +A+ F C+QFY++HR PFILQ+FGS++NY+ + G + +FY+I+P +Y +LR I+ L DNL IL+L + KPLKALDFCYE++ +WSVLEAV LCV VIVYAPDS RA+QM+IILQAILP ILRD IC + N E +K E AIQ+L ++++QLI T +++ R+T+ P G V E+ +G ++S +T + + + S LE + T+ V + ++ + ++ I S I P E ILQ++CDF + RLNE+GE+ + ELLD +S +RLSE+ QSIIK IP++ LL S +QR+ LE+ P VDW HESM+SCKALE L+ RLNR++ K+L+ + WD + LI++++LI+K+N+S+A +K++R L++ L++ ++ D + PY +SL F G ++S ++ TG + T +H T +G +PP KF+A VI+ AL+LQ+L + LKD CER + G T+ + + II L C AGRKDS +S EN+++ D+ +++L + S R N+ P+A + GY + S R +T ++ G + G ++LV L ++ Y+ + +SN R
Sbjct: 2134 PIQRYILSQVKNMYSNSFNLLNKSALLLTHEQLEKVVPLAWELLLETEEELVSSTACFILFCGVRSASLVQELLLAEMQHNSAHQRLSAILRFRALWTHRHHVWSRLDEGASAQLRLPPLFIEFVLPSPTLGYIGQDAPDPMWQIRKGTSAEEVQLKQNEATKTFVTASTSRRKQQQELLARALTAETLRRRDARRQFHLTTCPVLERAAIEPAFTKEHRDETLVDEGNVAGGTPGTGTSGGQNPIQEEFAAAVKRLSVAPLNRTMLVQSRSSSWRQGSIPWFRSSGLTHDAFPLGILRQDDRTSGMIPPLFPPQPLQQAQYIFPSALCAATVPLIHLLDDSSVNDDGIAVSTIAEHCIFQCLVEDTNLFLRFIFERLTRTAHKGELIFALRKMIQRLPELPKQSAHVIFNNLVGYIMFHVRTPNFNAPEAIASALSVLHLVVPHVQNIYFKDLKQTLRREQIDSTLLLTANLPCAKQFNVFDNDIGVAQLVRLHDENKDYQFEDILKDALESSGIPLNQINSYFLCDDRSGIICNNSHYIRDFYPFKRNHNPKLRIKQMEKNDGLHLLQQNALNLKFQEIGKVLFTTAVLQCTPSTQISNHVFFLHEELTKLPSFPRKALESEFGLYGLQELGEPLLGLDTVHKISWCELLSSLFERMPNTYPWSADLQLFLNVYNGTLILLAEDSSVLRQCLAFYIQCSHQFKMAFSTSGYAGILPTLLRVYNQQTHNAVLTQAVEFTCRQFYVMHRIPFILQLFGSLANYVAVGDERTGMDGDFYRIQPATLYRLLRLINRPLPDNLRILELCNVQKPLKALDFCYEDDEGNWSVLEAVNLCVAVIVYAPDSYRARQMLIILQAILPFILRDFFAICT--EENCGVEP-KKAEINAIQKLCIAIRQLIATTEFMARRTEDVRNLNMHAPGGPVERRPEQLMSNLGHSWSRKTVRTGRIMEIKSSIESSLEVTKPISPTIRLVGSGTEDLTDVDT--IQSPIVSRSFYEPKEVILQLACDFLSFTTARLNELGERQRVPELLDSRSHVRLSEIVQSIIKQIPSNPELLSSPGIQRYFLEVLPSVDWSHESMRSCKALEALLGRLNRTLPKLLEHASHKPRFCWDDIVRLIRSMYLIIKKNRSIAHLKEIRVLIDTLKRSVIFDPAGCLPALVKTRIDPYLPLSGWSSNTNVPGRQSLGDSLFGGISPESSSVGLSYTGRASRRGRLLNTTSEYGSHLTPSGASSVPPRKHPEAGAQRSLDNAFSFKFAAEVIRLIALVLQTLGPNFSLKDMCERCGPDYNARCPAILEGGFHTLAVYLGQLIIPLLFR-CSAGRKDSPTLSKENVFYAMDVCITALFAPVTSQNNNCR-------NERAPSAASGGYSSPSFIDTKEKSGRHVTEITSSGGRNPSPVGMELPGGSTLVKLINFSSLGYEQEDGTNSNLTR 3562 HSP 2 Score: 239.58 bits (610), Expect = 1.040e-58 Identity = 193/629 (30.68%), Postives = 296/629 (47.06%), Query Frame = 1
Query: 4111 SGANASASKGRARNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFP-------------------GSYMNSSAIPMSGDHQFMNNTNK--KIIFIQRQAGQMFHSWAEALGARLEYFLKI-----EQAADRFSNISEIQDEAKIRE------LQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTIS-----LKEPIYE--TSYNIDSTQDH------KRVQEIP-YRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTE---------IHPAP--------GNRRISFAF---------SLHSSNNSLDQTDES-------------GSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRA-ASHTRIGSIRYRKESSQSQVSTFTPESATV-----KEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDL 5724
SG++++A RA + + + ++ + A P V + ++++ LK G+ FSF+++ EPG I EP+LVA++LDL++PV+ARACLLLE A FV RCN+GEW WM+F P G+ + S A SG MN + I ++R AG++FH+W EALG RL F++ + A N S + +E L+ EENFLDD++VNP GDSCPYAL S +QLLL IT YLRE H LP+ T +++P+ + + + + + H ++ I + +SP++ G + + I G G +N + + P P G+RRISFA SL S+ SLD++ ES GS + K P A + N++ T RK S S E ++ L E Q ++ + + S A AS T++ S K QS+ S + ++ ++S + +T G+ E D++S++MPW+ V QF N TNF C+H +C P+C+ERQQ QCR L++ VK VY ++
Sbjct: 1310 SGSSSAAMMDRASDTSHSRGDGESAA-AQPLV---------EHRWVNAPALKEGLLEFSFLMECCEPGTILEPELVAALLDLDAPVVARACLLLECAAFVHRCNRGEWAGWMKFNLPSSFHHSAASSHPTSIRPSPGTGVGSGASAGSG----MNGDSSVSDIAALKRNAGRLFHAWGEALGRRLGNFIQQLNTNGQPAKSTSGNASGTATPDRRKETVPGQQFSALETEENFLDDASVNPTGDSCPYALLSAGVQLLLEITAYLREMHPRLPQPVTDEQASQPMRQPVGDQPSDSGLVAKRQHSYDPNAEKAGSISKHLNSSPSRAGTSFRAARRR-LSILMPIFGSGGSMNADEPEVDAEQPVLPEPNLKSRRNLGSRRISFAMFTETKDRKSSLAGSSTSLDRSPESDKQQNKSLLRHHRGSGSFKRPNPYAQDPLGVNFRRGSR-----------TSHRKFSDSGESSARLSPDVL-----EHSPSQLSDETSDQEPSTQMTSTSARASATQLTSKSRTKLDEQSKFHGVVRRSVSAALALRRQRASSILTSTTLATEQDGV----EHDSYSTYMPWIDSVIQFLNHTNFSCDHQSYCLPNCFERQQHQCRALMNGVKQVYGAEI 1903 HSP 3 Score: 207.608 bits (527), Expect = 4.404e-49 Identity = 97/206 (47.09%), Postives = 135/206 (65.53%), Query Frame = 1
Query: 109 YIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQE-------------------SKVPFSSTETKIMYSLHWIIMDAAAECED------NDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
++PL +QSFLLTQT SF + R+ C + E+V+VQNI+HG S +C AIQ ++RWQF+K AFPHV+HCA+ ++REK + S++ FS ETK++Y+LHWI++DAAAECED ++R N+ + +LHDLS+IQLF+YLFAP+++Q+ S F+TLKLE GL IW PL + QP PVK
Sbjct: 8 HVPLPVQSFLLTQTFSFLQTPSAREGVCTTFEKVIVQNILHGRSILLCEAIQSITRWQFVKAAFPHVVHCAAAMLREKLRHQLPTSKHMRSTVILSEAGGRSQLQFSQYETKLLYTLHWILLDAAAECEDAELEGTSNRANRTTK-YGFLHDLSSIQLFIYLFAPIIEQLQASDFETLKLEAGLAIWVPLMAFHQPARGTLPTPVK 212 HSP 4 Score: 127.872 bits (320), Expect = 5.899e-25 Identity = 74/195 (37.95%), Postives = 103/195 (52.82%), Query Frame = 1
Query: 3007 NNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNN-----------TRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLK---PAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGML 3549
N+ +A EI++++++ LGC Y H R TN + TR H+CL+ LY+ + F L RM +SDI+E LHA TG+C DPA ++ + Y N F Q G G+R +E + I+ L P + RLV R +L+ QEN L+ DIRQL Y +EVHGSTFRR ML M+
Sbjct: 1039 NHAMATEIVLRIVRTLGCSYGHHGSPTVGAREA---TTNVDQAKGHVLGETEETRRLAHDCLIHLYESNRPLFVRVLSRMISTMCISDIMEMLHALTGYCLDPAVRHVDHSKSLSKISTYANSFGQLTLGMGSRGAESIVISCILGPFLRRLVRCRSELVSQENLSLFGDIRQLFTYLREVHGSTFRRNMLVAMM 1230 HSP 5 Score: 108.612 bits (270), Expect = 4.183e-19 Identity = 56/162 (34.57%), Postives = 94/162 (58.02%), Query Frame = 1
Query: 10219 YGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVT 10704
+ ++ +RL FL LK+ ++ Y RH ++ R +++ ++ L Q GI LWKF DF+VT R PIF+ L+PF+RFK+++ + C T GEQA+QQ+++QK +GLHLP P+ A +L+EL ++ I+ + +F+Q + V+
Sbjct: 3644 FKGEFAHRLGFLGLKLLLVAYSRHASVRLRLLTAALTKLALNGQNGIQLWKFFDFLVTHRPPIFVHLLPFIRFKMAN----------------------LCCATPGEQAYQQIVSQKLMGLHLPVPQTTAVVLRELLSEMNTIQHDVQ-HFTQAHGKEGGVS 3782 HSP 6 Score: 72.0182 bits (175), Expect = 4.409e-8 Identity = 31/82 (37.80%), Postives = 53/82 (64.63%), Query Frame = 1
Query: 2383 VLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKP 2628
++ S +D+ I Y E+++EV G+VHYI NGQ++Y+V+L+AL+ + H S R+C ++ + LF+M I + K+K P
Sbjct: 751 LISHSFTDSDIIYHTTEKVDEVPGAVHYISVNGQLDYSVVLRALYWVSTEHKSTRVCVQLLRCLCTLFEMDIVDHASKQKPP 832 HSP 7 Score: 70.8626 bits (172), Expect = 1.155e-7 Identity = 33/57 (57.89%), Postives = 39/57 (68.42%), Query Frame = 1
Query: 1255 SQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEI-SLELRMSEEQEK 1422
S G LLA+H D+AV+RCLFC +W E GVYW L YL KRLL+I S RM +E K
Sbjct: 395 SYGSTCLLATHCDVAVIRCLFCAEWCEAGVYWSLTYLFKRLLQIRSARQRMEQETRK 451
BLAST of Protein unc-80 vs. TrEMBL
Match: A0A4S2LSC8 (UNC80 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005205 PE=4 SV=1) HSP 1 Score: 1255.74 bits (3248), Expect = 0.000e+0 Identity = 688/1442 (47.71%), Postives = 941/1442 (65.26%), Query Frame = 1
Query: 6202 PILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGG-----------SQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHE--------DDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYI----DFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTD--------KPFGKVG--DEKCSFRVGGNYS-QTQNSVVLEDQDESPYRLLEEGRFRKNTV--VSNNCDEPSGGNSRHIVSAIA------PHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSS------------PY------------AMNESLSSIQFSGRHDQTSPNHVTATGG--------DNTYSQATH-TYNG---IPP------------------KFSAMVIKFFALMLQSLESTYKLKDFCERFDQRF---------GTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTG----TQASTRFLTSTAAAN------TGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIR 10182
PI Y+ + V N+ N FN++NK ALLL + ++P+AWELLLE + ELV+S A ++ ++ +L Q+L+ E+QH +QR+SA+LRFR+LW R W RL++ AS QL+LPP +IEFVLPSPTLG+ G D PDP W IRK SAEEVQLKQNEA KTFVTAST+RRKQQQE+L +A+ AE RR+ AR++FHLTTC +LE+A+ E AF+KEH+DE +++G PIQEEF AAV+RLS A +NR + VQ+R+ SWR GSIP+ R++ + H+ DD S + P+ QPLQ AQ +FPS+LCAA++P+IHLLDD VN DG+AV+TIAEH ++QCLVEDT LFLR+I ERLTR K EL++ LRK+IQRLPELP QSAH +FNNLVGYIMF+VRTP+ +APE+IA ALS+L +VP VQNIYFKDLKQ LR+EQ+D TL++TANLPCAKQFNVFD D+ VAQLVRL DE KDY+F +ILK+AL+ S IP + Y LCDDRS II N+SHY+RDFY FKRNH PKLR+K+M DG HLLQ+NA NLKF EIGKV+F+ ++L+ TPS Q +NH++FLH+ELTK PSFPRKALESEF LY LG+ L G+D +HKISWC L+S LFERMP+++PW++D+ LFLN++NG LIL AED+++LR CLA IQ S FKM FS +GY GI+PT+LRVY++ HN VL +A+ F C+QFY++HR PFILQ+FGS++NY+ + G + +FY+I+P +Y +LR I+ L DNL IL+L + KPLKALDFCYE++ +WSVLEAV LCV VIVYAPDS RA+QM+IILQAILP ILRD IC + N E +K E AIQ+L ++++QLI T +++ R+T+ P G V E+ +G ++S +T + + + S LE + T+ V + ++ + ++ I S I P E ILQ++CDF + RLNE+GE+ + ELLD +S +RLSE+ QSIIK IP++ LL S +QR+ LE+ P VDW HESM+SCKALE L+ RLNR++ K+L+ + WD + LI++++LI+K+N+S+A +K++R L++ L++ ++ D + PY +SL F G ++S ++ TG + T +H T +G +PP KF+A VI+ AL+LQ+L + LKD CER + G T+ + + II L C AGRKDS +S EN+++ D+ +++L + S R N+ P+A + GY + S R +T ++ G + G ++LV L ++ Y+ + +SN R
Sbjct: 2134 PIQRYILSQVKNMYSNSFNLLNKSALLLTHEQLEKVVPLAWELLLETEEELVSSTACFILFCGVRSASLVQELLLAEMQHNSAHQRLSAILRFRALWTHRHHVWSRLDEGASAQLRLPPLFIEFVLPSPTLGYIGQDAPDPMWQIRKGTSAEEVQLKQNEATKTFVTASTSRRKQQQELLARALTAETLRRRDARRQFHLTTCPVLERAAIEPAFTKEHRDETLVDEGNVAGGTPGTGTSGGQNPIQEEFAAAVKRLSVAPLNRTMLVQSRSSSWRQGSIPWFRSSGLTHDAFPLGILRQDDRTSGMIPPLFPPQPLQQAQYIFPSALCAATVPLIHLLDDSSVNDDGIAVSTIAEHCIFQCLVEDTNLFLRFIFERLTRTAHKGELIFALRKMIQRLPELPKQSAHVIFNNLVGYIMFHVRTPNFNAPEAIASALSVLHLVVPHVQNIYFKDLKQTLRREQIDSTLLLTANLPCAKQFNVFDNDIGVAQLVRLHDENKDYQFEDILKDALESSGIPLNQINSYFLCDDRSGIICNNSHYIRDFYPFKRNHNPKLRIKQMEKNDGLHLLQQNALNLKFQEIGKVLFTTAVLQCTPSTQISNHVFFLHEELTKLPSFPRKALESEFGLYGLQELGEPLLGLDTVHKISWCELLSSLFERMPNTYPWSADLQLFLNVYNGTLILLAEDSSVLRQCLAFYIQCSHQFKMAFSTSGYAGILPTLLRVYNQQTHNAVLTQAVEFTCRQFYVMHRIPFILQLFGSLANYVAVGDERTGMDGDFYRIQPATLYRLLRLINRPLPDNLRILELCNVQKPLKALDFCYEDDEGNWSVLEAVNLCVAVIVYAPDSYRARQMLIILQAILPFILRDFFAICT--EENCGVEP-KKAEINAIQKLCIAIRQLIATTEFMARRTEDVRNLNMHAPGGPVERRPEQLMSNLGHSWSRKTVRTGRIMEIKSSIESSLEVTKPISPTIRLVGSGTEDLTDVDT--IQSPIVSRSFYEPKEVILQLACDFLSFTTARLNELGERQRVPELLDSRSHVRLSEIVQSIIKQIPSNPELLSSPGIQRYFLEVLPSVDWSHESMRSCKALEALLGRLNRTLPKLLEHASHKPRFCWDDIVRLIRSMYLIIKKNRSIAHLKEIRVLIDTLKRSVIFDPAGCLPALVKTRIDPYLPLSGWSSNTNVPGRQSLGDSLFGGISPESSSVGLSYTGRASRRGRLLNTTSEYGSHLTPSGASSVPPRKHPEAGAQRSLDNAFSFKFAAEVIRLIALVLQTLGPNFSLKDMCERCGPDYNARCPAILEGGFHTLAVYLGQLIIPLLFR-CSAGRKDSPTLSKENVFYAMDVCITALFAPVTSQNNNCR-------NERAPSAASGGYSSPSFIDTKEKSGRHVTEITSSGGRNPSPVGMELPGGSTLVKLINFSSLGYEQEDGTNSNLTR 3562 HSP 2 Score: 239.195 bits (609), Expect = 1.169e-58 Identity = 193/629 (30.68%), Postives = 296/629 (47.06%), Query Frame = 1
Query: 4111 SGANASASKGRARNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFP-------------------GSYMNSSAIPMSGDHQFMNNTNK--KIIFIQRQAGQMFHSWAEALGARLEYFLKI-----EQAADRFSNISEIQDEAKIRE------LQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTIS-----LKEPIYE--TSYNIDSTQDH------KRVQEIP-YRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTE---------IHPAP--------GNRRISFAF---------SLHSSNNSLDQTDES-------------GSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRA-ASHTRIGSIRYRKESSQSQVSTFTPESATV-----KEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDL 5724
SG++++A RA + + + ++ + A P V + ++++ LK G+ FSF+++ EPG I EP+LVA++LDL++PV+ARACLLLE A FV RCN+GEW WM+F P G+ + S A SG MN + I ++R AG++FH+W EALG RL F++ + A N S + +E L+ EENFLDD++VNP GDSCPYAL S +QLLL IT YLRE H LP+ T +++P+ + + + + + H ++ I + +SP++ G + + I G G +N + + P P G+RRISFA SL S+ SLD++ ES GS + K P A + N++ T RK S S E ++ L E Q ++ + + S A AS T++ S K QS+ S + ++ ++S + +T G+ E D++S++MPW+ V QF N TNF C+H +C P+C+ERQQ QCR L++ VK VY ++
Sbjct: 1310 SGSSSAAMMDRASDTSHSRGDGESAA-AQPLV---------EHRWVNAPALKEGLLEFSFLMECCEPGTILEPELVAALLDLDAPVVARACLLLECAAFVHRCNRGEWAGWMKFNLPSSFHHSAASSHPTSIRPSPGTGVGSGASAGSG----MNGDSSVSDIAALKRNAGRLFHAWGEALGRRLGNFIQQLNTNGQPAKSTSGNASGTATPDRRKETVPGQQFSALETEENFLDDASVNPTGDSCPYALLSAGVQLLLEITAYLREMHPRLPQPVTDEQASQPMRQPVGDQPSDSGLVAKRQHSYDPNAEKAGSISKHLNSSPSRAGTSFRAARRR-LSILMPIFGSGGSMNADEPEVDAEQPVLPEPNLKSRRNLGSRRISFAMFTETKDRKSSLAGSSTSLDRSPESDKQQNKSLLRHHRGSGSFKRPNPYAQDPLGVNFRRGSR-----------TSHRKFSDSGESSARLSPDVL-----EHSPSQLSDETSDQEPSTQMTSTSARASATQLTSKSRTKLDEQSKFHGVVRRSVSAALALRRQRASSILTSTTLATEQDGV----EHDSYSTYMPWIDSVIQFLNHTNFSCDHQSYCLPNCFERQQHQCRALMNGVKQVYGAEI 1903 HSP 3 Score: 207.608 bits (527), Expect = 4.555e-49 Identity = 97/206 (47.09%), Postives = 135/206 (65.53%), Query Frame = 1
Query: 109 YIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQE-------------------SKVPFSSTETKIMYSLHWIIMDAAAECED------NDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
++PL +QSFLLTQT SF + R+ C + E+V+VQNI+HG S +C AIQ ++RWQF+K AFPHV+HCA+ ++REK + S++ FS ETK++Y+LHWI++DAAAECED ++R N+ + +LHDLS+IQLF+YLFAP+++Q+ S F+TLKLE GL IW PL + QP PVK
Sbjct: 8 HVPLPVQSFLLTQTFSFLQTPSAREGVCTTFEKVIVQNILHGRSILLCEAIQSITRWQFVKAAFPHVVHCAAAMLREKLRHQLPTSKHMRSTVILSEAGGRSQLQFSQYETKLLYTLHWILLDAAAECEDAELEGTSNRANRTTK-YGFLHDLSSIQLFIYLFAPIIEQLQASDFETLKLEAGLAIWVPLMAFHQPARGTLPTPVK 212 HSP 4 Score: 127.872 bits (320), Expect = 6.362e-25 Identity = 74/195 (37.95%), Postives = 103/195 (52.82%), Query Frame = 1
Query: 3007 NNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNN-----------TRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLK---PAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGML 3549
N+ +A EI++++++ LGC Y H R TN + TR H+CL+ LY+ + F L RM +SDI+E LHA TG+C DPA ++ + Y N F Q G G+R +E + I+ L P + RLV R +L+ QEN L+ DIRQL Y +EVHGSTFRR ML M+
Sbjct: 1039 NHAMATEIVLRIVRTLGCSYGHHGSPTVGAREA---TTNVDQAKGHVLGETEETRRLAHDCLIHLYESNRPLFVRVLSRMISTMCISDIMEMLHALTGYCLDPAVRHVDHSKSLSKISTYANSFGQLTLGMGSRGAESIVISCILGPFLRRLVRCRSELVSQENLSLFGDIRQLFTYLREVHGSTFRRNMLVAMM 1230 HSP 5 Score: 108.612 bits (270), Expect = 4.326e-19 Identity = 56/162 (34.57%), Postives = 94/162 (58.02%), Query Frame = 1
Query: 10219 YGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVT 10704
+ ++ +RL FL LK+ ++ Y RH ++ R +++ ++ L Q GI LWKF DF+VT R PIF+ L+PF+RFK+++ + C T GEQA+QQ+++QK +GLHLP P+ A +L+EL ++ I+ + +F+Q + V+
Sbjct: 3644 FKGEFAHRLGFLGLKLLLVAYSRHASVRLRLLTAALTKLALNGQNGIQLWKFFDFLVTHRPPIFVHLLPFIRFKMAN----------------------LCCATPGEQAYQQIVSQKLMGLHLPVPQTTAVVLRELLSEMNTIQHDVQ-HFTQAHGKEGGVS 3782 HSP 6 Score: 72.0182 bits (175), Expect = 4.484e-8 Identity = 31/82 (37.80%), Postives = 53/82 (64.63%), Query Frame = 1
Query: 2383 VLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKP 2628
++ S +D+ I Y E+++EV G+VHYI NGQ++Y+V+L+AL+ + H S R+C ++ + LF+M I + K+K P
Sbjct: 751 LISHSFTDSDIIYHTTEKVDEVPGAVHYISVNGQLDYSVVLRALYWVSTEHKSTRVCVQLLRCLCTLFEMDIVDHASKQKPP 832 HSP 7 Score: 70.8626 bits (172), Expect = 1.165e-7 Identity = 33/57 (57.89%), Postives = 39/57 (68.42%), Query Frame = 1
Query: 1255 SQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEI-SLELRMSEEQEK 1422
S G LLA+H D+AV+RCLFC +W E GVYW L YL KRLL+I S RM +E K
Sbjct: 395 SYGSTCLLATHCDVAVIRCLFCAEWCEAGVYWSLTYLFKRLLQIRSARQRMEQETRK 451
BLAST of Protein unc-80 vs. TrEMBL
Match: A0A0X3P483 (Protein unc-80 homolog (Fragment) OS=Schistocephalus solidus OX=70667 GN=UNC80 PE=4 SV=1) HSP 1 Score: 1248.42 bits (3229), Expect = 0.000e+0 Identity = 624/1177 (53.02%), Postives = 830/1177 (70.52%), Query Frame = 1
Query: 6187 KSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDG--GSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDD-NGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDF-QGENS--NFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTD--------------KPFG---------KVGD------EKCSFRVGGNYSQTQNSVVLEDQDE--------------------SPYRLL-----EEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILL 9537
++ D P L+YL+ V +L + FN++NK ALLL + DI+P+AWELLLE DPEL +SAA ++ AA+K P Q+L++ EL H DVN R++A+LRFR LW R W RLE+ A+ KLPPP IE+VLPSPTLG+P +VPDP+W RK SAEEVQLKQNEA KTFVTAST+RRKQQQE+L +AV+A + + AR+ FH+TTC +LE AS E AFSK+H++E EDG G +QEEFN A R++S A +NR+LN+Q+R+ SWR+GSIP R N +DD+ G LT ++ Q AQC FPS LCAA++P+ LLDD V+ +G A++T+A+ V+WQCL EDT+LFLR + E+LTR KDEL+ +LRKLIQRLPELP Q+AH LFNNLVG IMFYVRTP+ AP+SIA L +L IVPFV+NIYFKDLKQ LR+EQ+D TL+VTANLPCAKQFNVFD+ + VAQLV+LQD+ KDYRF++IL EAL+ +++P+ +HHL+ LCDDRSNIIRNSSHYVRDFY FKRNHIPKLRL ++ E G LLQRNAF+LK E+GKV+ +IL+ TP + +NH+ FLH+EL K PSFPRKALE+EF+L D+G +GK L +D +HK++WC+L++ +F++MPS+FPW+S++ LFLN++NG L+LHAED ++LR C+A +Q + F M+FSVNGYL I+PTI+RVY NLHN VL +AI F K FYI+HRTPFILQMFG I+NYID Q E S NFY++ P +Y +LR I D +D+L ILQL + NKPLKALDFCY +++ WS+ EAV LCVTV VYAP+S R++QMM+ILQAI+P ILRDL IC +T RK E Q+IQQL+V++KQLICT +++TR+ D P G ++ D E S G N + Q + D D+ S LL +EG F S+N PSG S++ P EAILQ++ +F T + RL E+GE+ + +LLD K+ MRLSELAQSIIK P + NLL+S+ALQRF ++ P V+W HES++SCKALE L+ RL+R++ K+L R+ + WD +TN+I+++++ RN+SVA +K+++ EYL++ +++
Sbjct: 1078 QNADSPELVYLDTQVQSLRSSFFNLLNKSALLLTNEQLEDIIPLAWELLLEADPELTSSAATFILFAAVKCPNFVQKLVYTELHHVDVNNRLNAVLRFRILWVNRHHVWARLEEGAALCFKLPPPSIEYVLPSPTLGNPTVEVPDPAWKTRKGTSAEEVQLKQNEATKTFVTASTSRRKQQQELLARAVSAAKAQEDEARRVFHMTTCPVLELASAEAAFSKDHREEASAEDGTVGVTNSVVQEEFNLAARKVSFAPMNRSLNMQSRSFSWRNGSIPIFRDNVTLMDDDEVAGGGLT--LLCTHQFQVAQCFFPSCLCAAALPLTDLLDDCAVSREGTAISTVAQQVIWQCLTEDTSLFLRNVFEKLTRAPHKDELICILRKLIQRLPELPMQTAHILFNNLVGCIMFYVRTPNFDAPDSIASVLCILHMIVPFVKNIYFKDLKQTLRREQIDGTLLVTANLPCAKQFNVFDDRICVAQLVKLQDDNKDYRFSDILSEALETNSVPQSEHHLHVLCDDRSNIIRNSSHYVRDFYPFKRNHIPKLRLMRVDKETGQQLLQRNAFSLKVQEVGKVLLFKTILQTTPMSTMSNHLMFLHEELVKLPSFPRKALETEFALCDTGEMGKPLLAIDTIHKLTWCQLLNSMFQKMPSTFPWSSELQLFLNVYNGTLVLHAEDASILRHCMAFYLQCAFQFNMVFSVNGYLSILPTIIRVYHHNLHNGVLTQAIEFTIKHFYIMHRTPFILQMFGCIANYIDLSQDEFSQQNFYRVLPETLYRLLRTIGRDCQDSLGILQLCNFNKPLKALDFCYADDSQGWSIFEAVNLCVTVQVYAPESYRSRQMMVILQAIVPFILRDLSTIC---SEECSTGDVRKFELQSIQQLSVTIKQLICTTEWMTRRVDDVRSVVSSQSSHGSAPGGPCVSGNSVKRLADQAPKIPEWASALSGMNMAAPQPDLHTYDGDKGVSIRRRRRRHHRGSMSLKRSASSLLNKRTNQEG-FAATATTSSN-PTPSGWRK----SSVEPREAILQIASEFLTVANIRLTELGERQRFSDLLDGKAYMRLSELAQSIIKQFPYNPNLLKSQALQRFFTDVLPIVEWGHESLRSCKALETLVGRLSRTLPKMLDTPSIRKQVKWDCVTNMIRSLYMTTHRNRSVAQLKEIKIFAEYLKRSVVI 2243 HSP 2 Score: 162.155 bits (409), Expect = 2.413e-35 Identity = 99/230 (43.04%), Postives = 133/230 (57.83%), Query Frame = 1
Query: 4192 ASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFP-----GSYMNSS------AIPMSGDHQFMN--------NTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQ 4824
S V + + +R+ +D LK + FSF+L+ EPG +PE +LVAS LDL +PVLARACLLL+ A FV +CN+GEWP+W++ FP +++N AI +SG N K IQ AG++FH+WAEALG R+ FL D SNI+ D R+ EENFLDD+ VN GD+CPYAL + +QLL+ ITT+LRE+HQ
Sbjct: 318 VSANVDVKAGKMTVERRLVDISALKEDLRDFSFLLECSEPGSLPESELVASFLDLNAPVLARACLLLQCAYFVNKCNRGEWPAWIKMNFPMPVQQATHINLQPPAQPIAISISGPAASSNFDVENRGVGIQKNSAQIQWAAGRLFHAWAEALGIRIMEFL------DNPSNITS-SDAFLHRD---FGHEENFLDDALVNASGDNCPYALLVLAVQLLMEITTFLRESHQ 537 HSP 3 Score: 132.88 bits (333), Expect = 1.500e-26 Identity = 62/138 (44.93%), Postives = 87/138 (63.04%), Query Frame = 1
Query: 3136 RLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGML 3549
R H C L+LY + F F R+ +++++EFLHA TGFC DP +++ NY+N F QS +GEGTR +EGV I+N + PL+ RLV RK+L QEN L++++R LL Y K VHG+TFRR +L +L
Sbjct: 100 RRHAHHCFLRLYHLDNNLFYCFFSRLVAACPITELMEFLHALTGFCLDPTTIERP---DPPNYQNNFGQSYSGEGTRGAEGVIISNMMGPLLRRLVRCRKELATQENIGLFTEVRHLLGYLKTVHGNTFRRALLCALL 234
BLAST of Protein unc-80 vs. TrEMBL
Match: A0A3Q0KT99 (UNC80 domain-containing protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 1229.93 bits (3181), Expect = 0.000e+0 Identity = 644/1373 (46.90%), Postives = 895/1373 (65.19%), Query Frame = 1
Query: 6181 KEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLED------------GGSQPG---PIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYI----DFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTD-----KPFGKVGDEKCSFRVGG-NYSQTQNSVVLEDQDESPYRLLEEGRFRKNTV-VSNN--CDE--------------------------------PSGGNS-RHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNL-SRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYN-----------GIPP-----------------------------------------KFSAMVIKFFALMLQSLESTYKLKDFCER----FDQRF-----GTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSL 9930
K S + PI YL+ ++ NL + FN++NK ALLL + A ++P+AWELLLE D E+ +SAA ++ ++ P + Q++I E++HE QR +A+LRFR+LWC RF W RLE++A +QL++PP +IEFVLPSPTLG+PG + PDP W IRK SAEEVQLKQNEA KTFVTAST+RRKQQQE+L +A+ E RR+ ARQ FHLTTC +LE+A+ E AFSKEH+DE ++D GG Q G Q+E+ AAVRRLS A INR + QARNLSWR SIP+ R + + H+D+D + +QPLQ AQ VFPS+LC+AS+ +I+LLDD +N G AV TIAE+V++ CL+EDT LFLR+I ERLTR+ KDEL+++LRK+IQRLPELP Q+AHALFNNLVGYIMF++RTPS +AP+SIA ALS+L ++P+VQNIYFKDLKQ +R+EQ+D TL++TANLPCAKQFNVFD + VAQLVRLQDE KDY+F +ILK+ L S+I E + Y LCD+RSNIIRNSSHY+RDFY FKRNH PKLRL++ + G +LLQ+NA +LKF EIGKV F+ S+L+ TP+ Q NH++FLH+ELTK PSFPRKALES+F+LYD + G+ L+ +D +HK+SWC L+S LF MP ++PW+SD+ +FLN++NG LILHAED+++LR CLA IQ FK +F+ GY GI+PT++RVY++N HN VL +AI F +QFY++HRTPFILQ+ G I+NY+ + G FY+I+P +Y +LR IS L+DNL IL+L + KPL+ALDFCY++E +WS+LE + LCV VIVYAPDS R++QM+IILQA++PLIL+DL IC N +K E AIQ+++++++QLI T ++++R+ + G +C G + +V + +S ++ L++ ++ + V ++ N C+E P+ S H +A P EA+LQ++C+F ++C RL EM EK + +LLD KS MRL+++ Q ++K + N + L S ALQR+ LE+ P +DW HES++SCKA+E L+ RLNR++ K+L+ + S+ W+ LI++V+ I+KRN+SVA MK++R L E L+K I+ D S LSS F PNH T+ G ++ + G+P +F+ VI+ +L LQ L LKD CER ++ RF G +T++I I+ L C AGRKDS +S +N+++ D+ +++L
Sbjct: 2278 KHHSGELPIQCYLDTHIKNLCSSGFNLLNKAALLLTNNQLAKMLPLAWELLLETDTEMSSSAACFILFCGVRCPQIVQEMILDEMRHEKPTQRFNAILRFRTLWCHRFHVWSRLEENAPSQLRVPPSFIEFVLPSPTLGYPGFEAPDPVWQIRKGTSAEEVQLKQNEATKTFVTASTSRRKQQQELLARAIATETMRRREARQSFHLTTCPVLERATIEPAFSKEHRDEGNIDDSIANSSGFNSGVGGGQIGVSNSTQDEYTAAVRRLSLAPINRTVLNQARNLSWRQSSIPWLRNSVIAHDDEDRWLSGFHSLFPSQPLQQAQLVFPSALCSASVLLINLLDDTAINEHGTAVNTIAEYVIFNCLLEDTPLFLRFIFERLTRIKNKDELIFILRKMIQRLPELPMQTAHALFNNLVGYIMFHIRTPSFNAPQSIASALSVLHLVIPYVQNIYFKDLKQTMRREQIDSTLLLTANLPCAKQFNVFDNSIGVAQLVRLQDENKDYQFEDILKDVLSASDILEDERCSYYLCDERSNIIRNSSHYIRDFYSFKRNHTPKLRLRQYDKKHGMYLLQQNALSLKFQEIGKVSFTLSVLRCTPTAQIPNHVFFLHEELTKLPSFPRKALESDFNLYDWPTYGRPLFALDTIHKLSWCHLISSLFMMMPKTYPWSSDLQIFLNVYNGTLILHAEDSSVLRQCLAFFIQCCYQFKTVFATTGYSGIVPTLVRVYNQNTHNPVLTQAIEFTFRQFYVMHRTPFILQLLGCIANYVTTNNEIIGVGDEFYRIQPGAVYRLLRVISRPLDDNLRILELCNIQKPLEALDFCYDDEEANWSILEVINLCVAVIVYAPDSYRSRQMLIILQALMPLILKDLSYICAE---EGNGTDPKKAELSAIQKISIAMRQLISTAEFMSRRIEDIRQLNYLAPGGPTECRKETPGLLLTGVATRLVNYEAAKSNFKSLDKTKYNETAVKITRNELCNEINTLPVNKGFPLSVSSNVSRERDIQSNQMLRNPAAATSGHHRPTAYEPREAVLQLACEFLSTCSGRLLEMEEKQRISDLLDAKSHMRLADITQFMLKQVSNSPDFLVSSALQRYFLEVLPVIDWSHESLRSCKAVECLLGRLNRTLPKMLEFAIRSKATHHWNEFVKLIRSVYYILKRNRSVAHMKEIRVLAEILKKAIVFDVS-----RCLSS--FPKSRLDIQPNHATSRYGRPSFGEVLFGITSQESSSISASVGVPKQSNKMKHIPLNGDAGSYCSPRHSNQEAWPETDLDDSDKYPCQFTTEVIRLLSLFLQILGPHCSLKDLCERISPEYNIRFPTLREGGFQTLVIYLNNLILPMLFRGC-AGRKDSPTLSRDNVFYALDVCITAL 3639 HSP 2 Score: 197.208 bits (500), Expect = 6.917e-46 Identity = 92/211 (43.60%), Postives = 133/211 (63.03%), Query Frame = 1
Query: 103 SNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQES---------------------KVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGI-------SYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
S++IPL IQSFL +QT SF + RD C + E+VLVQNI+HG S +C AI +SRW+F+K A PHV+HC ++++REK +S ++ FS TETK++Y+LHWI++DAA+ECED + E Y+HDL+++QLF+YL+AP+++Q+ + F TLKLE GL +W PL Y QP+ ++PVK
Sbjct: 6 SSHIPLPIQSFLFSQTCSFLQKPSARDGVCTTFEKVLVQNILHGRSIVLCEAIHSISRWKFVKAALPHVLHCGAIMLREKLRDKSAADLPHQKHTLNSCGLSHDRTRLNFSQTETKLLYTLHWILLDAASECEDAELEASNHPASIPKHSTDRYVHDLASLQLFIYLYAPIIEQLKPTDFDTLKLEAGLRLWIPLMEYCQPNRGTLSSPVK 216 HSP 3 Score: 189.119 bits (479), Expect = 1.703e-43 Identity = 107/265 (40.38%), Postives = 152/265 (57.36%), Query Frame = 1
Query: 4117 ANASASKGRARNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKK------------IIFIQRQAGQMFHSWAEALGARLEYF------------LKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKS 4839
+N S+S A N E+ PT +T + ++I+ LK G+ F+F+LD EPG+IPEPQL+A++ DL++PVLARACLLLE A V RCN+GEW WM+F P S+ +S+ S NN ++ I I+R AG +F++W EALG RL+YF ++ + D+ + +D + ++ E+NFLDD++VNP G+SCPYAL +V +QLL ITTYLRETHQ LP+S
Sbjct: 1399 SNGSSSTIAASFEN---EYPSRSKSECPTTDQSTGQMIIEHRWINLSALKEGLFDFAFLLDCCEPGLIPEPQLIAALFDLDAPVLARACLLLECAFLVHRCNRGEWAGWMKFNLPSSFRSSAGFISSNTTNSNNNPSQANENTNNNNHPVDISEIKRVAGYLFYAWGEALGHRLQYFTSLMSSSNSSIITNLDPSGDKVYGSDKSKD---VNYRSNVEMEQNFLDDASVNPTGESCPYALLTVGVQLLFEITTYLRETHQRLPQS 1657 HSP 4 Score: 129.028 bits (323), Expect = 3.150e-25 Identity = 90/267 (33.71%), Postives = 152/267 (56.93%), Query Frame = 1
Query: 2839 SRDFS---APSQS---DEDGSDESRSKSAPPVRPS-RFEKQLLSN---KPKLERPTAEELNSGGMSNNDI------AMEXXXXXXXXLGCGYDHS---------CQNQSKERRTWPPGTNPNNT-RLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPAS--LKPAGINSRN--NYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGML 3549
++DFS +P S ++D R KS+ ++P R ++ +S +PK R +++ S +SN+ I A E++I++I+ +GC + HS +Q +E+ +PNN R TH+CL+ L++++ F+ + R+ +++D+VE LH++TGFC DP + + + N ++ NY N F ++ TG+ TR +EG+ ++ P V RLV R++L QEN L+SDIRQL Y +E+HGSTFR+ ML +L
Sbjct: 1057 AKDFSPLGSPQSSIDLEKDPCSTPRIKSSGNIQPRLRNNEKFMSKSAYRPK-SRVQQKQVVSCDISNHLIRTHFTLAAEMLIRIIRSVGCRHGHSNSPNFMNHHYHHQQEEQEN---SVDPNNHFRSLTHDCLIYLHQLNPNLFKRLIIRIVSSSTVADLVEILHSFTGFCLDPVTRCYEHSDQNRKSYLNYGNSFGENDTGQDTRGAEGLIVSYLFGPFVRRLVRCRRELSSQENVSLFSDIRQLFTYIREIHGSTFRKNMLVALL 1319 HSP 5 Score: 121.324 bits (303), Expect = 6.544e-23 Identity = 54/157 (34.39%), Postives = 92/157 (58.60%), Query Frame = 1
Query: 10219 YGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQ 10689
+ ++ +RL FL LK+ + Y RH ++ + + + ++ L Q GI LWKF DF+VT R P+F+ L+PF+RFK+ + ++C +QGEQA+QQ++NQK +GLHLP P+ A+IL+ L+ +L+ I + + ++ N+
Sbjct: 3838 FKAEFAHRLGFLGLKLILAAYTRHAAVRMKLLVAALTQLALNGQSGIQLWKFFDFLVTYRPPLFVHLLPFIRFKM----------------------ALLQCASQGEQAYQQIVNQKLIGLHLPIPQTVASILRSLSNELQIINSDIKAFSKRSYNE 3972 HSP 6 Score: 70.4774 bits (171), Expect = 1.305e-7 Identity = 28/63 (44.44%), Postives = 44/63 (69.84%), Query Frame = 1
Query: 5524 SIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVY 5712
+ G ++ + +++SHMPW+ V +FAN T+F C+H + C +C+E QQ QCR LL+A+K VY
Sbjct: 1945 AFGDNETYHVHDYTSHMPWVDAVIEFANYTSFNCDHQNSCASNCFEYQQHQCRNLLNAMKQVY 2007 HSP 7 Score: 69.3218 bits (168), Expect = 3.091e-7 Identity = 31/84 (36.90%), Postives = 56/84 (66.67%), Query Frame = 1
Query: 2359 NQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKR 2610
N E + + L RS +D+ I Y E+++EV G+ +YI NG ++Y+VIL++L+ H+S R+C +++ ++ LFD+GIF+ +
Sbjct: 836 NDEQLFAKTLPRSLTDSDIIYHSSEKVDEVPGAAYYITPNGHLDYSVILRSLYWCSTVHTSSRVCFNLVSCLSVLFDLGIFDMK 919 HSP 8 Score: 69.3218 bits (168), Expect = 3.447e-7 Identity = 28/48 (58.33%), Postives = 35/48 (72.92%), Query Frame = 1
Query: 1252 PSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLE 1395
PS G + A+H DLAV+RCL+CP+WSE G+YW L YL RLL+I E
Sbjct: 422 PSVGTYCMFATHCDLAVIRCLYCPEWSESGIYWSLCYLFNRLLQIRSE 469
BLAST of Protein unc-80 vs. TrEMBL
Match: A0A4Z2CN76 (Protein unc-80 OS=Schistosoma japonicum OX=6182 GN=EWB00_009090 PE=4 SV=1) HSP 1 Score: 1212.59 bits (3136), Expect = 0.000e+0 Identity = 652/1374 (47.45%), Postives = 896/1374 (65.21%), Query Frame = 1
Query: 6181 KEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDG------------GSQPG---PIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGE----NSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKP-----FGKVGDEKCSFR------------------VGGNYSQTQNSVVLE-DQDESPYRLLEE--------------------------GRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNL-DWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSP--YAMNESLSSIQF---SGRHDQTS----------------------------PNHVTATGGDNTYSQATHTYNGIPP------------KFSAMVIKFFALMLQSLESTYKLKDFCER----FDQRF-----GTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSL 9930
K S + PI YL+ +V NL + FN++NK ALLL + A I+ +AWELLLE + E+ +SAA ++ ++ P + Q++I E++HE QR +A+LRFR+LWC RF W RLE +AS+QL++PP +IEFVLPSPTLG+PG + PDP W IRK SAEEVQLKQNEA KTFVTAST+RRKQQQE+L +A+ E RR+ ARQ FHLTTC +LE+A+ E AFSKEHKDE +++ G Q G Q+E+ AAVRRLS A INR + QARNLSWR SIP+ R + + H+DDD + +QPLQ AQ VFPS+LC+AS+P+IHLLDD +N G AV TIAE+V++ CL+EDTTLFLR+I ERLTR+ KDEL++VLRK+IQRLPELP Q+AHALFNNLVGYIMF++RTPS +AP+SIA ALS+L ++P+VQNIYFKDLKQ +R+EQ+D TL++TANLPCAKQFNVFD + VAQLVRLQDE KDY+F +ILK+ L S+I E + + Y LCD+RSNIIRNSSHY+RDFY FKRNH PKLRL++ + G +LLQ+NA NLKF EIGKV F+ S+L+ TP+ Q NH++F+H+ELTK PSFPRKALES+ LYD + G+ L+ +D +HK+SWC L+S LF MP ++PW+SD+ +FLN++NG LILHAED+++LR CLA IQ FK +FS GY GI+PT++RVY+++ HN VL +AI F +QFY++HRTPFILQ+ GSI+NY+ E FY+I+P +Y +LR IS +DNL +L+L + KPL+ALDFCY++E +WS+LE + LCV VIVYAPDS R++QM++ILQA++PLIL+DL IC + S T+ +K E AIQ+++++++QLI T +++TR+ + G +CS N+ ++ + E D++ S + L E + +N VV ++ H +A P EA+LQ++C+F +SC RL EM EK + +LLD KS MRL+++AQS++K + N + L S ALQR+ LE+ P +DW HES+KSCKALE L+ RLNR++ K L+ + + + WD + LI++V+ I+KRN+SVA MK++R L+E L+K I+ D S + +S IQ + H + S H+ G +Y H+ P +F+ VI+F +L Q L LKD CER ++ RF G +T++I I+ L C AGRKDS +S +N+++ D+ +++L
Sbjct: 2119 KPHSAELPIQCYLDTHVKNLCSSSFNLLNKAALLLTNNQIAKILLLAWELLLETETEMSSSAACFILFCGVRCPQIVQEMILDEMKHEKPTQRFNAILRFRTLWCHRFHVWSRLEINASSQLRVPPSFIEFVLPSPTLGYPGFEAPDPVWQIRKGTSAEEVQLKQNEATKTFVTASTSRRKQQQELLARAIATETMRRREARQLFHLTTCPVLERAAIEPAFSKEHKDESNIDENIANASGGSSGAGGGQIGVSSSTQDEYTAAVRRLSLAPINRTVLNQARNLSWRQSSIPWLRNSVLAHDDDDRWLSGFHSLFPSQPLQQAQLVFPSALCSASVPLIHLLDDTALNEHGTAVNTIAEYVIFNCLLEDTTLFLRFIFERLTRIKNKDELMFVLRKMIQRLPELPMQTAHALFNNLVGYIMFHIRTPSFNAPQSIASALSVLHLVIPYVQNIYFKDLKQTMRREQIDSTLLLTANLPCAKQFNVFDNSIGVAQLVRLQDENKDYQFDDILKDVLSTSDISEDERNSYYLCDERSNIIRNSSHYIRDFYSFKRNHTPKLRLRQFDKKHGMYLLQQNALNLKFQEIGKVFFTLSVLRCTPTAQIPNHVFFVHEELTKLPSFPRKALESDLGLYDWPTYGRPLFALDTIHKLSWCHLISNLFMMMPKTYPWSSDLQIFLNVYNGTLILHAEDSSVLRQCLAFFIQCCYQFKTVFSTTGYTGIVPTMIRVYNQHTHNAVLTQAIEFTFRQFYVMHRTPFILQLLGSIANYVTINSEIIGVGDEFYRIQPGTLYRLLRVISRPSDDNLRVLELCNIQKPLEALDFCYDDEEANWSILEVINLCVAVIVYAPDSYRSRQMLVILQALVPLILKDLSYIC--AEEGSGTDP-KKAELTAIQKISIAMRQLISTAEFMTRRIEDTRQLNYLAPGGPAECSKEPPVYLLTDVASRLVNYEAARSNFKSSEKTKNSETDKENSKHELCNEINSLSINKGFPLYISSNVSRERDIQPNQISRNPVV--------AASNHHRSTAYEPREAVLQLACEFLSSCSGRLFEMEEKQRISDLLDAKSHMRLADIAQSMLKQVSNSPDSLASSALQRYFLEVLPVIDWSHESLKSCKALECLLSRLNRTLPKTLEFAVKSKAIRHWDEIVKLIRSVYYILKRNRSVAHMKEIRILVETLKKAIVFDISGCLASFPKSRLDIQLNHATSHHSRPSFGEVLFGITSQESSSISASIGVVKQSNKVKHIPLNGDAGSYCSPKHSSQEHWPETMPNDSDRYARQFATEVIRFLSLFSQVLGPHCSLKDLCERISPDYNIRFPTLLEGGFQTLVIYLNNLILPLLFRGC-AGRKDSPTLSRDNVFYALDVCITAL 3480 HSP 2 Score: 152.91 bits (385), Expect = 1.731e-32 Identity = 119/374 (31.82%), Postives = 186/374 (49.73%), Query Frame = 1
Query: 355 SKVPFSSTETKIMYSLHWIIMDAAAECEDNDRE-------NKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLL-DSNCKNHWIKSALCGGDNSVTVSCGHQTKLS-PAPLARLSDICPLSTV----SGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKN---KIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRL 1428
+++ FS TETK++Y+LHWI++DAA+ECED + E + + G Y+HDL+++QLF+YL+APL++Q+ S F TLKLE GL++W PL + QP+ ++PVK + R+ + V I K S + K M K S+ +G I++ IDS++ ++ LL DS H ++ + + +QT L+ L L+ + P + D +E N+ S S L+ P+ + S LN ID YK K+ + T P+ G +LA+H D+AV+RCL+CP+W E GVYW L YL RL++I E S+ ++L
Sbjct: 32 TQLNFSQTETKLLYTLHWILLDAASECEDAEIEASNHPASKQKNSGDRYVHDLASLQLFIYLYAPLIEQLIPSDFDTLKLEAGLHLWIPLMEHCQPNRGTLSSPVKFVTNDLCIFHRS---VIVNMDDRGISKVSPILKDKMMGKSVSAETSGEM--PFIIHAGSKIDSKLPSAVKAFELLVDSASIPHVEANSDGSLISEQNIPDSNQTHLTYEDNLTGLTSLQPPKAIPECMDDDEEFIEKSVSETNATASTASSVLLYIQ------APKQEQEYVASGFDRIQKFLNSFID-PYKQLSEKLKHSTIDNEFIQPAIGSHCMLATHCDIAVIRCLYCPEWYESGVYWSLCYLFNRLIQIRSEWLKSKPNSRKL 393 HSP 3 Score: 123.25 bits (308), Expect = 1.343e-23 Identity = 54/146 (36.99%), Postives = 89/146 (60.96%), Query Frame = 1
Query: 10219 YGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDE 10656
+ ++ +RL FL LK+ ++ Y RH ++ + + +V++ L Q GI LWKF DF+VT R P+F+ L+PF+RFK+ + ++C +QGEQA+QQ++NQK +GLHLP P+ A+IL+ L+ +L+ I +
Sbjct: 3676 FKAEFAHRLGFLGLKLILVAYTRHATVRMKLLVAVLTQLALNGQNGIQLWKFFDFLVTYRPPLFVHLLPFIRFKM----------------------ALLQCASQGEQAYQQIVNQKLIGLHLPIPQTIASILRSLSNELQMINSD 3799 HSP 4 Score: 119.398 bits (298), Expect = 2.027e-22 Identity = 57/142 (40.14%), Postives = 88/142 (61.97%), Query Frame = 1
Query: 3136 RLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPAS--LKPAGINSRN--NYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGML 3549
R H+CL+ L++++ F+ + R+ +++D+V LH++TGFC+DP + K + N ++ NY N F Q+ + R +EG+ I+ P V RLV R++L QEN L+SDIRQL Y +EVHGSTFR+ ML +L
Sbjct: 1110 RSLAHDCLIYLHELNPNLFKRVMTRVVSSSTVADLVAILHSFTGFCSDPVTRYYKRSDQNMKSCLNYANSFGQTDASQDIRGAEGLIISYLFGPFVRRLVKCRRELSSQENVSLFSDIRQLFTYIREVHGSTFRKNMLVALL 1251 HSP 5 Score: 78.9518 bits (193), Expect = 4.257e-10 Identity = 83/293 (28.33%), Postives = 123/293 (41.98%), Query Frame = 1
Query: 4585 ALGARLEYFLKIEQAADRF------SNISEIQDEAKIRELQI---LDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPK----------------SRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTS------------PTQGGVELHSPDSDDQDSIE----SIVGEIGQIN----TEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQ 5328
ALG RL+YF + ++ S ++ K ++L + E+NFLDD++VNP G+SCPYAL ++ +QLL ITTYLRETHQ LP+ SR +K P+ + T K TS P G +SP+ + +E S V + +N T A +RRISFA N+S + + +GS A + ++EA +++S K+LLRK R+SGSF+
Sbjct: 1404 ALGHRLQYFTSLMSTSNSSIVTNSNSKGDKVYGSDKNKDLSFRSNTEMEQNFLDDASVNPTGESCPYALLTIGVQLLFEITTYLRETHQRLPQDSTNYDGKCSQSSQYSSRNSVVKRPLTREASGDKKTDMFKHTYSTGNSGTSFKGAKRRLSILMPIFGSTGNNSPEDSTINELEKQSSSTVKPVITMNADKSTGSRRATSSRRISFAV----MNDSKNMVNSTGSSAIYLDQ--SLEANESQHRLS-----------------------------VSKSLLRKHRDSGSFR 1661 HSP 6 Score: 75.8702 bits (185), Expect = 3.456e-9 Identity = 31/76 (40.79%), Postives = 51/76 (67.11%), Query Frame = 1
Query: 5506 STGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKR 5733
+T + + G ++ +D+++SHMPW+ V +FAN T+F C+H + C +C+E QQ QCR LL+A+K VY +L +
Sbjct: 1780 TTHHTLAFGDNETYFVDDYTSHMPWIDAVIEFANYTSFNCDHQNSCASNCFELQQHQCRNLLNAIKQVYDSELENK 1855 HSP 7 Score: 70.4774 bits (171), Expect = 1.225e-7 Identity = 33/85 (38.82%), Postives = 57/85 (67.06%), Query Frame = 1
Query: 2368 PIRKQ----VLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKR 2610
PI +Q VL RS +D+ I Y E+++EV G+ +YI NG ++Y+V+L++L+ H+S R+C ++ ++ LFD+GIF+K+
Sbjct: 745 PINEQLFTRVLPRSLTDSDIIYHSSEKIDEVPGAAYYITPNGHLDYSVLLRSLYWCSTVHTSSRVCFQLVRCLSVLFDLGIFDKK 829
BLAST of Protein unc-80 vs. Ensembl Cavefish
Match: unc80 (unc-80 homolog (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-140106-167]) HSP 1 Score: 727.628 bits (1877), Expect = 0.000e+0 Identity = 490/1555 (31.51%), Postives = 790/1555 (50.80%), Query Frame = 1
Query: 6175 SVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDE---DVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYK--IKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKI-----EAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRV-GGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIA------PHEAILQVSCDFYTSCHNRL----NEMGE-KHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILK---------DNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNP--IIHS----NYQASRLP-HTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKD---EWSGYFSQNQNQAVAVTIDAY 10716
S E +D +L Y+ V +L +++ K A +L +D++ DI P AWELLL D + A+AA + +L A+K+P +++ E QH + +QR++++L+F ++W R+Q W R+E+ A K+PPP I F LPSP LG P + DP W + + + +K+F + +R Q+ E + K + EE++R+ R+ +T I ++A +E S + E ++ N A RRLS + + N RN S+R GS+ +S + V EDD+N T ++ LQ Q VFP+ +CAA +PI+HL++DGDV DGVAV+ +A+ V+W CL+ED L LR+ LE+LT +DEL+Y+LRKL+ + +LP Q++H LFN LVG IM++VRTP ++I+ L+ LW++V +V+ ++FKDLKQ ++KEQ + L+VTA++P K V + D+ V +D +F +LKE L+ NIPE Y L D R N+I + YVRD Y F+R+ P+L L M PE G L+Q+ F+ K E+G+V+F S+ + P+ +H+ L ++L + PSFPR A+++EF+L++ LGK+L+GMD LHK+ W +L+ +F MPS +PW +I LFLN+FNG L+LH ED+A+LR A I + HF +FS++GY I+PT+L+ Y+ N +L++ I F C+QFYILHR PFILQ+F S++ ++F S + ++D+L ++ + D L+ L+L+ KPL++LDFCY NE+ +S+ E++ LCVTV+ YAP+S R+ QM+++L+A++P L+ L SN+++ + E AI LA S++ L+ ++D+ G G + + GG +++ +V D L+EEG+ G + IA P E++L + +FY C RL N GE + ALELLD KS MRL+E+A S++K+ P D + S+ L+R++ E+ P DW E+++ AL ++ RL+R NKI K L R++ W + + FL V N V+ + + L +R ++ P ++ + L + S Y P FS V++ A+ +Q+L+ + L F T + + N++IP +L G+G KDS Q+ ++ + +++ L P II + N+ P H P + G +G + +QA+ Y+ LV + GN + YRLS ++A+ +K GG+ W F+DFIV R PIF+ L PF++ K+ + PA E+Q E + I + +P C++++ E +L+ +K+ S Y + V + AY
Sbjct: 1445 SSAEGKKDSGMLKYIRTQVMSLAPAPLSLLIKAAPILTDDMYGDIQPAAWELLLSVDEHIAAAAAAMFLLCAVKVPDAVTEMMMAEFQHSEASQRINSVLKFYTIWRFRYQVWPRMEEGAQQIFKIPPPSINFTLPSPILGMPCVPMFDPPWVPINAGTVPDA--ISEDQSKSFSARAVSRSHQRAEHILKNMQQEEEKRRLGREASIITAIPIAQEACYEPTCSPPPEQEE-----------EEDVVNLASRRLSVSPSCASSNSH-RNYSFRRGSV-WSVRSVVSAEDDENT---TEHTPTHHMLQPPQSVFPACICAAVLPIVHLMEDGDVREDGVAVSAVAQQVLWNCLIEDPALVLRHFLEKLTVSNRQDELMYMLRKLLLNIGDLPAQTSHILFNYLVGLIMYFVRTPCEWGMDAISATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQLPVH-----EDTQFEALLKECLEFFNIPEARSAHYFLMDKRWNLIHYAKTYVRDIYPFRRSVSPQLNLVHMAPEKGQELIQKQVFSRKLEEVGRVLFLISLTQRMPAMHKQSHVSLLQEDLLRLPSFPRTAIDAEFTLFNE-PLGKELFGMDTLHKVLWIKLLEEMFLGMPSEYPWGDEIMLFLNVFNGALLLHPEDSALLRQYTATAINTAVHFNHLFSLSGYQWILPTMLQTYADYESNPLLRRGIEFCCRQFYILHRKPFILQLFASVAPLLEFTTCTSTGLSKGVSAQCLFDLLVSLEGETADGLDALELVKAEKPLRSLDFCYGNEDLVFSISESIKLCVTVVAYAPESYRSLQMLMVLEALVPCYLQKL---------KSNSQALESVSVARDEIAAIAALATSLQALLPMTAPQMSRSDQ--GHKGGTTANHTMSGGPNTRSDQYLVFWLSDN--LHLMEEGQ---------------GMPREELDERIAREEFRRPRESLLNICTEFYKHCGPRLKILQNVAGEPRVTALELLDIKSHMRLAEIAHSLLKLAPYDTLTMESRGLRRYITEMLPITDWSSEAVR--PALILILKRLDRMFNKIHKMPTLRCARPQALYSRSVLW-LLAGFLPLPFLSV--NTLVSVLPPLLHL--RMRGCVMGVVGPSSVADGLPLLHLS-------------------------PYLSPPLPFSTAVVRLVAMQIQALKDDFPLSHVISPF-----TNQERREGMLLNLLIPFVLTVGSGSKDSPQIEQAEVFLLLQTVINILLPPRIISTSRSKNFVLDASPAHCSTPGETGKDLRREGLAESTSQAA--------------YLALKVVLVCFER-----------------------------QLGNQW-YRLSLQVKEMAL-----------------------RKVGGLAFWDFIDFIVRTRIPIFVLLRPFIQCKLLTQ-----------------PA-----ESQEEITARHHIADQLERRFIPRSLCKSSLFAEFNNELKILKEAVHSGSAYQGKTSISTVGTSTSAY 2821 HSP 2 Score: 135.576 bits (340), Expect = 1.008e-30 Identity = 87/215 (40.47%), Postives = 128/215 (59.53%), Query Frame = 1
Query: 4231 KDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNI-SEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYE 4872
K++ ++ +++GM F F+L+ EPG IP+ ++A+ LDLE+PV+ARA L LE A FV RCN+G WP WM+ G ++N + +S + NK+ +Q A + F+ W +A+G RL + + +NI I D+ R + DEEE+FLDD+TVNP +CP+ALK QLLL ITT+LRET LP+ RT EP+ +
Sbjct: 1076 KNKNIVNLGAIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARASLFLECARFVHRCNRGNWPEWMK----GHHVNITKRGLSRGRSPVAG-NKRNNKLQWNAAKHFYQWGDAIGTRLSELCHSDSESP--ANILGFIYDDESKRRARKEDEEEDFLDDNTVNPSKCACPFALKMAACQLLLEITTFLRETFPCLPRPRT----EPLVD 1279 HSP 3 Score: 131.724 bits (330), Expect = 1.500e-29 Identity = 66/186 (35.48%), Postives = 107/186 (57.53%), Query Frame = 1
Query: 196 SLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDN--------------------------------DRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
S ERVLV+N +HGLSP + AIQ +SRW+ ++ A PHV+HC S+L+ R K + K+ + ETK++++LHW++++AA EC + EN+ + Y +++ ++LFV+LFAPL+++I ES T +L +GL IW P+ ++QPD+ F+A +K
Sbjct: 27 SFERVLVENKLHGLSPALTEAIQSISRWELVQAALPHVLHCTSILLSNRNKLGHQDKLGVA--ETKLLHTLHWMLLEAAQECHQDLGHGWSGGGSSGSSAFLQPLGNQGNVERNGSTPEENEYARAKLYHKNMATVELFVFLFAPLINRIKESDL-TFRLASGLVIWQPMWEHRQPDVPAFSALIK 209 HSP 4 Score: 92.8189 bits (229), Expect = 9.316e-18 Identity = 61/187 (32.62%), Postives = 97/187 (51.87%), Query Frame = 1
Query: 3001 MSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQT----HECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGML 3549
+S + +A+ ++IK++K LGC Y C + G + + R+Q CL LYK+ +F+ + SL++IV+FLHA GFC +P + AG NN+ ++S+ + E V + + L+ R S+ +L EN LY DIRQL+ + KE HG+ FRRV L+ +L
Sbjct: 706 LSTHRLALTMLIKIVKSLGCAY--GCGEGHR-------GLSGDRLRMQVTMSAQNCLTSLYKLDKVQFRQTMKEYVNKDSLNNIVDFLHALLGFCMEPITDNKAGFG--NNFATGGDKSLA----QNMEAVVVGCMFKSLITRCASTTHELHSPENLGLYCDIRQLVQFIKESHGNVFRRVALSALL 877 HSP 5 Score: 73.9442 bits (180), Expect = 4.156e-12 Identity = 45/131 (34.35%), Postives = 67/131 (51.15%), Query Frame = 1
Query: 5374 SLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVAT 5766
SL ++SHT + S E SQ +P SA+ E S P G S+ G+ DN+ +M W+ ++ N+ +F+C HVDFCHP CY+R R C RL+ A+K +Y + R+ S+ T
Sbjct: 1301 SLNSSSHT-LKSDTACDEKKSSQEPLGSPWSAS--EPSIEP----EGGGSTGGVE-----DNYHRNMSWLHIMILLCNQQSFICTHVDFCHPRCYQRHSRSCARLVRAIKLLYGETVDSLRENSSGISINT 1419 HSP 6 Score: 59.6918 bits (143), Expect = 8.987e-8 Identity = 38/124 (30.65%), Postives = 67/124 (54.03%), Query Frame = 1
Query: 2296 TSFFDDSPKQEKLSNEQQL-QRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKK--KKPDQENSSMLSK 2658
T FF + K KL N + + EP+ L RS +D+ INY +EE + + G+ ++I NG ++ +L+AL++++ S RIC+ ++ + CL +G+ KK K D+ + L+K
Sbjct: 525 TDFFTEHIK--KLCNPNPIPEMPCEPLACSNLPRSLTDSCINYSCLEERDTIEGTNNFILKNGMLDLTAVLRALYAVLTHDISSRICDVALNIIECLLQLGVVPDLAKKVSKPEDKPKEAELAK 646
BLAST of Protein unc-80 vs. Ensembl Nematostella
Match: EDO35053 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SML6]) HSP 1 Score: 335.88 bits (860), Expect = 1.546e-98 Identity = 189/507 (37.28%), Postives = 298/507 (58.78%), Query Frame = 1
Query: 7384 VGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDV-FVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNH-IPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPW-TSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIK---------PHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDS---WSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTR 8859
VG M+Y RT A +S+A LSL W++VP V+ ++ KD+KQ L+KE D +++ AN+P AK+ V + +++ + + +E F++++ N+ ERD L D +S + YVRD + ++ P+L L+ + PE L Q AF K + G++ +ILK P N H FLH E ++ SFPRKAL+S+F+LY G GK+L+GMD++HKI W +LV+ LF+ PS FPW +D++LF+N+ NG ++LH ED AM+R+ +A I + HF IF+ +G+ + P++L+VY+ + N ++ +AI F QFY LH+ P +LQ+F S++ + + + +++ P +Y +L ++ ++ D L+IL+L+ +KPLKA+D CY NE D+ V A+ LCVTV+ +AP+S RA QMM++L AILP L L + N + E+ +K EA AI L S+ LI + D LTR
Sbjct: 4 VGVAMYYARTNKPGAQDSVALVLSLTWELVPSVKGLFLKDIKQCLKKEHCDAAMLIFANVPGAKKLAVTCCNTESMSEKIPVNEEMT---FSKVISYLRTRFNLNERD---LWLIDTKSKQLLEERDYVRDVFAHRKGFPSPQLSLEHVDPESAFLLRQAQAFTSKLADTGRIAMCLAILKAVP---NQKHSSFLHGEFSRQTSFPRKALDSDFALYSGGVKGKELFGMDVIHKIYWVKLVAALFQYTPSDFPWGPADLNLFINVINGAILLHCEDAAMIRLGIASLINIAIHFSHIFAGDGFHFVFPSLLQVYAHHQGNDMVTRAIEFALSQFYALHQKPCLLQLFASVAPILLLETRLEDATELEPDDPTALVPPKCLYTLLASLDKNVPDELDILELVHADKPLKAMDSCYGNEIDAPGESKVDIALRLCVTVVDFAPESKRATQMMVVLSAILPYYLESLSE----ESENGDMEATKK-EAAAISALCTSINVLIKSSDVLTR 496 HSP 2 Score: 53.1434 bits (126), Expect = 2.235e-6 Identity = 32/107 (29.91%), Postives = 63/107 (58.88%), Query Frame = 1
Query: 9079 PHEAILQVSCDFYTSCHNRLNEMGE---KHKAL-ELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKIL 9387
P A+L + D+ + C R+ E+ + +AL +LLD SI+ L+E+ S++K+ D + S +QR+ML+ P +DW ++++ A+ ++ RL++ NK++
Sbjct: 599 PRNALLVLVADYVSICTRRVEEIRKVLPTRQALPDLLDDISIILLAEIMYSLMKLAVYDPITMNSPGVQRYMLQALPLIDWSPDAVEP--AVNLVLKRLSKIFNKLI 703
BLAST of Protein unc-80 vs. Ensembl Nematostella
Match: EDO35055 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SML9]) HSP 1 Score: 119.783 bits (299), Expect = 2.488e-30 Identity = 70/198 (35.35%), Postives = 112/198 (56.57%), Query Frame = 1
Query: 55 MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFF---LNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFT 639
MTN + + F+ +S IPL IQ++ QT+ L K ++ACI+LERV+ +N I L P++ SA++ V RW F+ ++ P+V+ C + L+ + S++E +++Y+L WI+ +A A C D EN+ LH ++ I+LFV L P V +I E+ T +LE G +W PL ++K P L FT
Sbjct: 1 MTNKSFAIREFNVERRS--IPLAIQTYFWRQTSQLLKTKLVKRQYESACIALERVICENRIQDLQPSLASAVKSVPRWYFVHSSVPYVIQCCAALLSNRHQLGYFDRLSNSERELLYTLQWILYEAPAICNIEDPENQ-------LHPMTTIELFVNLLIPHVFKIHENDL-TFRLEYGQQLWKPLWSHKLPPLPAFT 188
BLAST of Protein unc-80 vs. Ensembl Nematostella
Match: EDO35052 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SML4]) HSP 1 Score: 57.7658 bits (138), Expect = 9.159e-8 Identity = 33/141 (23.40%), Postives = 64/141 (45.39%), Query Frame = 1
Query: 10228 DYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIK 10650
D LY+ ++L +K+ ++C+ + I S I + + G+ W F+DF ++ R+P++L L+P ++ K AS IK T E+ + + + H + RC+ I+++ +L IK
Sbjct: 135 DSLYQAAYLGMKLLIVCFEDQLATEWHLIFSAIDKVVDNEMCGLAFWDFIDFAISHRSPLYLMLLPLIQIK----------------------ASVIKHHTHAERTHKLQVIENLARPHH-AARCKNAIIQKFMDELTAIK 252
BLAST of Protein unc-80 vs. Ensembl Medaka
Match: ENSORLT00000003055.2 (pep primary_assembly:ASM223467v1:2:15021945:15026221:1 gene:ENSORLG00000002461.2 transcript:ENSORLT00000003055.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 142.124 bits (357), Expect = 9.322e-37 Identity = 78/233 (33.48%), Postives = 125/233 (53.65%), Query Frame = 1
Query: 79 KAFDESNK--SNYIPLQIQSFLLTQTNSFFLNKNTR--DNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLM--REKFSQESKVPFSSTETKIMYSLHWIIMDAAAECED------------------------------------NDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVK 651
K+ DE+ IP IQ+FL +QT++F K + + +C+S ERVLV+N +HGLS + AIQ +SRW+ ++ A PHV+HC S+L+ R K + K+ ETK++++LHW+++DAA EC E++ + + ++ ++LFV+L APL+ +I ES T +L +GL IW P+ ++QPD+ FTA +K
Sbjct: 5 KSLDENEPECGKGIPFAIQTFLWSQTSAFLRPKLGKQYEASCVSFERVLVENKLHGLSRELSEAIQSISRWELVQAALPHVLHCTSILLSNRNKLGHQDKL--GVAETKLLHTLHWMLLDAAQECNHEPSLGHGWSGGGSGSSAFLQPVGDQGSSPGAPGSSPGSEEDENARAKLFHKSMATVELFVFLLAPLIHRIKESDL-TFRLASGLVIWQPMWEHRQPDIPAFTALIK 234
BLAST of Protein unc-80 vs. Planmine SMEST
Match: SMESG000014375.1 (SMESG000014375.1) HSP 1 Score: 7491.35 bits (19436), Expect = 0.000e+0 Identity = 3836/3857 (99.46%), Postives = 3837/3857 (99.48%), Query Frame = 1
Query: 55 MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLLDSNCKNHWIKSALCGGDNSVTVSCGHQTKLSPAPLARLSDICPLSTVSGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKNKIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLXXXXXXXXXXXXXXXXTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSSKLRNQMLITGLYGARLPSSPRQQRNIKIQDESVIPEELGDSGSDKDERRSSLPSDKLGIKLCPVYTEVEALLPPKKSRKTVTHKRQNGTKFKPITSKIKLTKYSDFSGCHENPIVQPEIQVSAEMDTKAPMFNXXXXXXXXXXXXXXFTLEKDSLSDEPGLCSSEVPLSSTKKTTSFFDDSPKQEKLSNEQQLQRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKPDQENSSMLSKRRNQLRNKKTKSNGQSPVAPPRFDAXXXXXXXXXXXXXXXXXXXXXXXXXMMINHGNYQNSRDFSAPSQSDEDGSDESRSKSAPPVRPSRFEKQLLSNKPKLERPTAEELNSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNIFKRYSSAVHNSTPDSNSLPIHVPIYRRGKKRESLCSQTYQIANDVREPDDNTGEXXXXXXXXXXXXXXXXXXXLVCDPDLDAAPPSPTKYVVXXXXXXXXXXXXXXXTSGANASASKGRARNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVATGHRXXXXXXXXXXXXXXXGPYXXXXXXXXXXXXXHSVGERGSCDTDIDASMQLLLHRGVSESDEKKLSLFPRSRRKESMFGNHSPHRRKDSVPLFDKFLKSRTXXXXXXXXXSSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVTIDAYVNKSSIRNIIPSLTNDSLTNSSICNQSVQGSVGFGNSKDNSRTTYLVXXXXXXXXXXXXXXKEGGNIICRYQQVQNPHRSDAILTVSSVDSLPSQATLEEDVPVKKYSGRLTRGETRNKKSVKLHWKQRPGSMVAGKSSSLAPDRPHHKQSTISGMSTPXXXXXXXXXXXXXXXXXXPYLRESLTRSRPEELIEMKGVQSFPVDXXXXXXXXXXLLKRSHNIYRSRSEETEETNISPRDSLIPSLDSRHKVVIIESAYSADKANSEEALLTACGAGVTLAESESSNASVTEYSSLIRLKPPNE 11625
MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLLDSNCKNHWIKSALCGGDNSVTVSCGHQTKLSPAPLARLSDICPLSTVSGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKNKIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLSASF SSMWDRSMSISTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSSKLRNQMLITGLYGARLPSSPRQQRNIKIQDESVIPEELGDSGSDKDERRSSLPSDKLGIKLCPVYTEVEALLPPKKSRKTVTHKRQNGTKFKPITSKIKLTKYSDFSGCHENPIVQPEIQVSAEMDTKAPMFNLPDDPATALDPLPDFTLEKDSLSDEPGLCSSEVPLSSTKKTTSFFDDSPKQEKLSNEQQLQRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKPDQENSS+LSKRRNQLRNKKTKSNGQSPVAPPRFDAQRSSLSSSLQIRSSSSVGRRDRRVSMMINHGNYQNSRDFSAPSQSDEDGSDESRSKSAPPVRPSRFEKQLLSNKPKLERPTAEELNSGGMSNNDIAMEIIIKVIKILGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNIFKRYSSAVHNSTPDSNSLPIHVPIYRRGKKRESLCSQTYQIANDVREPDDNTGETVIDSVTVSVTDSRSRARSLVCDPDLDAAPPSPTKYVVNDPDSFSPPSPNRNSTSGANASASKGR RNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESG KARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVATG RESVDNCESSENSEEEGPYSASLGGSLAAALSHSVGERGSCDTDIDASMQLLLHRGVSESDEKKLSLFPRSRRKESMFGNHSPHRRKDSVPLFDKFLKSRTAAAAAAAAASSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETILINYIENIIIPLLLCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPN QASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRSSSVSHSEKSLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVTIDAYVNKSSIRNIIPSLTNDSLTNSSICNQSVQGSVGFGNSKDNSRTTYLVRNAISRNSSRRINAKEGGNIICRYQQVQNPHRSDAILTVSSVDSLPSQATLEEDVPVKKYSGRLTRGETRNKKSVKLHWKQRPGSMVAGKSSSLAPDRPHHKQSTISGMSTPVGSAVAAAQAAQLYGSAAPYLRESLTRSRPEELIEMKGVQSFPVDETESSFSESSLLKRSHNIYRSRSEETEETNISPRDSLIPSLDSRHKVVIIESAYSADKANSEEALLTACGAGVTLAESESSNASVTEYSSLIRLKPPNE
Sbjct: 1 MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLLDSNCKNHWIKSALCGGDNSVTVSCGHQTKLSPAPLARLSDICPLSTVSGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKNKIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLSASFPSSMWDRSMSISTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSSKLRNQMLITGLYGARLPSSPRQQRNIKIQDESVIPEELGDSGSDKDERRSSLPSDKLGIKLCPVYTEVEALLPPKKSRKTVTHKRQNGTKFKPITSKIKLTKYSDFSGCHENPIVQPEIQVSAEMDTKAPMFNLPDDPATALDPLPDFTLEKDSLSDEPGLCSSEVPLSSTKKTTSFFDDSPKQEKLSNEQQLQRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKPDQENSSILSKRRNQLRNKKTKSNGQSPVAPPRFDAQRSSLSSSLQIRSSSSVGRRDRRVSMMINHGNYQNSRDFSAPSQSDEDGSDESRSKSAPPVRPSRFEKQLLSNKPKLERPTAEELNSGGMSNNDIAMEIIIKVIKILGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNIFKRYSSAVHNSTPDSNSLPIHVPIYRRGKKRESLCSQTYQIANDVREPDDNTGETVIDSVTVSVTDSRSRARSLVCDPDLDAAPPSPTKYVVNDPDSFSPPSPNRNSTSGANASASKGRTRNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGLKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVATGRRESVDNCESSENSEEEGPYSASLGGSLAAALSHSVGERGSCDTDIDASMQLLLHRGVSESDEKKLSLFPRSRRKESMFGNHSPHRRKDSVPLFDKFLKSRTAAAAAAAAASSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETILINYIENIIIPLLLCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPN----------------QASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRSSSVSHSEKSLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVTIDAYVNKSSIRNIIPSLTNDSLTNSSICNQSVQGSVGFGNSKDNSRTTYLVRNAISRNSSRRINAKEGGNIICRYQQVQNPHRSDAILTVSSVDSLPSQATLEEDVPVKKYSGRLTRGETRNKKSVKLHWKQRPGSMVAGKSSSLAPDRPHHKQSTISGMSTPVGSAVAAAQAAQLYGSAAPYLRESLTRSRPEELIEMKGVQSFPVDETESSFSESSLLKRSHNIYRSRSEETEETNISPRDSLIPSLDSRHKVVIIESAYSADKANSEEALLTACGAGVTLAESESSNASVTEYSSLIRLKPPNE 3841
BLAST of Protein unc-80 vs. Planmine SMEST
Match: SMESG000014375.1 (SMESG000014375.1) HSP 1 Score: 7325.33 bits (19005), Expect = 0.000e+0 Identity = 3772/3857 (97.80%), Postives = 3773/3857 (97.82%), Query Frame = 1
Query: 55 MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLLDSNCKNHWIKSALCGGDNSVTVSCGHQTKLSPAPLARLSDICPLSTVSGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKNKIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLXXXXXXXXXXXXXXXXTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSSKLRNQMLITGLYGARLPSSPRQQRNIKIQDESVIPEELGDSGSDKDERRSSLPSDKLGIKLCPVYTEVEALLPPKKSRKTVTHKRQNGTKFKPITSKIKLTKYSDFSGCHENPIVQPEIQVSAEMDTKAPMFNXXXXXXXXXXXXXXFTLEKDSLSDEPGLCSSEVPLSSTKKTTSFFDDSPKQEKLSNEQQLQRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKPDQENSSMLSKRRNQLRNKKTKSNGQSPVAPPRFDAXXXXXXXXXXXXXXXXXXXXXXXXXMMINHGNYQNSRDFSAPSQSDEDGSDESRSKSAPPVRPSRFEKQLLSNKPKLERPTAEELNSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNIFKRYSSAVHNSTPDSNSLPIHVPIYRRGKKRESLCSQTYQIANDVREPDDNTGEXXXXXXXXXXXXXXXXXXXLVCDPDLDAAPPSPTKYVVXXXXXXXXXXXXXXXTSGANASASKGRARNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVATGHRXXXXXXXXXXXXXXXGPYXXXXXXXXXXXXXHSVGERGSCDTDIDASMQLLLHRGVSESDEKKLSLFPRSRRKESMFGNHSPHRRKDSVPLFDKFLKSRTXXXXXXXXXSSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVTIDAYVNKSSIRNIIPSLTNDSLTNSSICNQSVQGSVGFGNSKDNSRTTYLVXXXXXXXXXXXXXXKEGGNIICRYQQVQNPHRSDAILTVSSVDSLPSQATLEEDVPVKKYSGRLTRGETRNKKSVKLHWKQRPGSMVAGKSSSLAPDRPHHKQSTISGMSTPXXXXXXXXXXXXXXXXXXPYLRESLTRSRPEELIEMKGVQSFPVDXXXXXXXXXXLLKRSHNIYRSRSEETEETNISPRDSLIPSLDSRHKVVIIESAYSADKANSEEALLTACGAGVTLAESESSNASVTEYSSLIRLKPPNE 11625
MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLLDSNCKNHWIKSALCGGDNSVTVSCGHQTKLSPAPLARLSDICPLSTVSGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKNKIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLSASF SSMWDRSMSISTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSSKLRNQMLITGLYGARLPSSPRQQRNIKIQDESVIPEELGDSGSDKDERRSSLPSDKLGIKLCPVYTEVEALLPPKKSRKTVTHKRQNGTKFKPITSKIKLTKYSDFSGCHENPIVQPEIQVSAEMDTKAPMFNLPDDPATALDPLPDFTLEKDSLSDEPGLCSSEVPLSSTKKTTSFFDDSPKQEKLSNEQQLQRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKPDQENSS+LSKRRNQLRNKKTKSNGQSPVAPPRFDAQRSSLSSSLQIRSSSSVGRRDRRVSMMINHGNYQNSRDFSAPSQSDEDGSDESRSKSAPPVRPSRFEKQLLSNKPKLERPTAEELNSGGMSNNDIAMEIIIKVIKILGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNIFKRYSSAVHNSTPDSNSLPIHVPIYRRGKKRESLCSQTYQIANDVREPDDNTGETVIDSVTVSVTDSRSRARSLVCDPDLDAAPPSPTKYVVNDPDSFSPPSPNRNSTSGANASASKGR RNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESG KARK RKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVATG RESVDNCESSENSEEEGPYSASLGGSLAAALSHSVGERGSCDTDIDASMQLLLHRGVSESDEKKLSLFPRSRRKESMFGNHSPHRRKDSVPLFDKFLKSRTAAAAAAAAASSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETILINYIENIIIPLLLCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPN QASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRSSSVSHSEKSLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFK ASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVTIDAYVNKSSIRNIIPSLTNDSLTNSSICNQSVQGSVGFGNSKDNSRTTYLVRNAISRNSSRRINAKEGGNIICRYQQVQNPHRSDAILTVSSVDSLPSQATLEEDVPVKKYSGRLTRGETRNKKSVKLHWKQRPGSMVAGKSSSLAPDRPHHKQSTISGMSTPVGSAVAAAQAAQLYGSAAPYLRESLTRSRPEELIEMKGVQSFPVDETESSFSESSLLKRSHNIYRSRSEETEETNISPRDSLIPSLDSRHKVVIIESAYSADKANSEEALLTACGAGVTLAESESSNASVTEYSSLIRLKPPNE
Sbjct: 1 MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLLDSNCKNHWIKSALCGGDNSVTVSCGHQTKLSPAPLARLSDICPLSTVSGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKNKIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLSASFPSSMWDRSMSISTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSSKLRNQMLITGLYGARLPSSPRQQRNIKIQDESVIPEELGDSGSDKDERRSSLPSDKLGIKLCPVYTEVEALLPPKKSRKTVTHKRQNGTKFKPITSKIKLTKYSDFSGCHENPIVQPEIQVSAEMDTKAPMFNLPDDPATALDPLPDFTLEKDSLSDEPGLCSSEVPLSSTKKTTSFFDDSPKQEKLSNEQQLQRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKPDQENSSILSKRRNQLRNKKTKSNGQSPVAPPRFDAQRSSLSSSLQIRSSSSVGRRDRRVSMMINHGNYQNSRDFSAPSQSDEDGSDESRSKSAPPVRPSRFEKQLLSNKPKLERPTAEELNSGGMSNNDIAMEIIIKVIKILGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNIFKRYSSAVHNSTPDSNSLPIHVPIYRRGKKRESLCSQTYQIANDVREPDDNTGETVIDSVTVSVTDSRSRARSLVCDPDLDAAPPSPTKYVVNDPDSFSPPSPNRNSTSGANASASKGRTRNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGLKARKG-----------------------------------------RKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVATGRRESVDNCESSENSEEEGPYSASLGGSLAAALSHSVGERGSCDTDIDASMQLLLHRGVSESDEKKLSLFPRSRRKESMFGNHSPHRRKDSVPLFDKFLKSRTAAAAAAAAASSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETILINYIENIIIPLLLCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPN----------------QASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRSSSVSHSEKSLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFK----------------------ASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVTIDAYVNKSSIRNIIPSLTNDSLTNSSICNQSVQGSVGFGNSKDNSRTTYLVRNAISRNSSRRINAKEGGNIICRYQQVQNPHRSDAILTVSSVDSLPSQATLEEDVPVKKYSGRLTRGETRNKKSVKLHWKQRPGSMVAGKSSSLAPDRPHHKQSTISGMSTPVGSAVAAAQAAQLYGSAAPYLRESLTRSRPEELIEMKGVQSFPVDETESSFSESSLLKRSHNIYRSRSEETEETNISPRDSLIPSLDSRHKVVIIESAYSADKANSEEALLTACGAGVTLAESESSNASVTEYSSLIRLKPPNE 3778
BLAST of Protein unc-80 vs. Planmine SMEST
Match: SMESG000014375.1 (SMESG000014375.1) HSP 1 Score: 7166.24 bits (18592), Expect = 0.000e+0 Identity = 3718/3857 (96.40%), Postives = 3733/3857 (96.79%), Query Frame = 1
Query: 55 MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLLDSNCKNHWIKSALCGGDNSVTVSCGHQTKLSPAPLARLSDICPLSTVSGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKNKIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLXXXXXXXXXXXXXXXXTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSSKLRNQMLITGLYGARLPSSPRQQRNIKIQDESVIPEELGDSGSDKDERRSSLPSDKLGIKLCPVYTEVEALLPPKKSRKTVTHKRQNGTKFKPITSKIKLTKYSDFSGCHENPIVQPEIQVSAEMDTKAPMFNXXXXXXXXXXXXXXFTLEKDSLSDEPGLCSSEVPLSSTKKTTSFFDDSPKQEKLSNEQQLQRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKPDQENSSMLSKRRNQLRNKKTKSNGQSPVAPPRFDAXXXXXXXXXXXXXXXXXXXXXXXXXMMINHGNYQNSRDFSAPSQSDEDGSDESRSKSAPPVRPSRFEKQLLSNKPKLERPTAEELNSGGMSNNDIAMEXXXXXXXXLGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNIFKRYSSAVHNSTPDSNSLPIHVPIYRRGKKRESLCSQTYQIANDVREPDDNTGEXXXXXXXXXXXXXXXXXXXLVCDPDLDAAPPSPTKYVVXXXXXXXXXXXXXXXTSGANASASKGRARNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGSKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVATGHRXXXXXXXXXXXXXXXGPYXXXXXXXXXXXXXHSVGERGSCDTDIDASMQLLLHRGVSESDEKKLSLFPRSRRKESMFGNHSPHRRKDSVPLFDKFLKSRTXXXXXXXXXSSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTFVTASTTRRKQQQEMLEKAVNAEEQRRKFARQEFHLTTCSILEKASFEVAFSKEHKDELGLEDGGSQPGPIQEEFNAAVRRLSTALINRNLNVQARNLSWRHGSIPFSRANFVYHEDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETXXXXXXXXXXXXXXXCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPNQVGPAALNKGYLGTGTQASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRXXXXXXXXXXLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFKVSDRGSFFTRLNNFQNSKKKNPASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVTIDAYVNKSSIRNIIPSLTNDSLTNSSICNQSVQGSVGFGNSKDNSRTTYLVXXXXXXXXXXXXXXKEGGNIICRYQQVQNPHRSDAILTVSSVDSLPSQATLEEDVPVKKYSGRLTRGETRNKKSVKLHWKQRPGSMVAGKSSSLAPDRPHHKQSTISGMSTPXXXXXXXXXXXXXXXXXXPYLRESLTRSRPEELIEMKGVQSFPVDXXXXXXXXXXLLKRSHNIYRSRSEETEETNISPRDSLIPSLDSRHKVVIIESAYSADKANSEEALLTACGAGVTLAESESSNASVTEYSSLIRLKPPNE 11625
MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLLDSNCKNHWIKSALCGGDNSVTVSCGHQTKLSPAPLARLSDICPLSTVSGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKNKIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLSASF SSMWDRSMSISTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSSKLRNQMLITGLYGARLPSSPRQQRNIKIQDESVIPEELGDSGSDKDERRSSLPSDKLGIKLCPVYTEVEALLPPKKSRKTVTHKRQNGTKFKPITSKIKLTKYSDFSGCHENPIVQPEIQVSAEMDTKAPMFNLPDDPATALDPLPDFTLEKDSLSDEPGLCSSEVPLSSTKKTTSFFDDSPKQEKLSNEQQLQRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKPDQENSS+LSKRRNQLRNKKTKSNGQSPVAPPRFDAQRSSLSSSLQIRSSSSVGRRDRRVSMMINHGNYQNSRDFSAPSQSDEDGSDESRSKSAPPVRPSRFEKQLLSNKPKLERPTAEELNSGGMSNNDIAMEIIIKVIKILGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNIFKRYSSAVHNSTPDSNSLPIHVPIYRRGKKRESLCSQTYQIANDVREPDDNTGETVIDSVTVSVTDSRSRARSLVCDPDLDAAPPSPTKYVVNDPDSFSPPSPNRNSTSGANASASKGR RNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESG KARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVATG RESVDNCESSENSEEEGPYSASLGGSLAAALSHSVGERGSCDTDIDASMQLLLHRGVSESDEKKLSLFPRSRRKESMFGNHSPHRRKDSVPLFDKFLKSRTAAAAAAAAASSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTF V A RRK +QE +LEKA ++E + + ++EF+ L+T I + + S H + +DDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETILINYIENIIIPLLLCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPN QASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRSSSVSHSEKSLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFK ASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVTIDAYVNKSSIRNIIPSLTNDSLTNSSICNQSVQGSVGFGNSKDNSRTTYLVRNAISRNSSRRINAKEGGNIICRYQQVQNPHRSDAILTVSSVDSLPSQATLEEDVPVKKYSGRLTRGETRNKKSVKLHWKQRPGSMVAGKSSSLAPDRPHHKQSTISGMSTPVGSAVAAAQAAQLYGSAAPYLRESLTRSRPEELIEMKGVQSFPVDETESSFSESSLLKRSHNIYRSRSEETEETNISPRDSLIPSLDSRHKVVIIESAYSADKANSEEALLTACGAGVTLAESESSNASVTEYSSLIRLKPPNE
Sbjct: 1 MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLERVLVQNIIHGLSPTICSAIQIVSRWQFIKTAFPHVMHCASLLMREKFSQESKVPFSSTETKIMYSLHWIIMDAAAECEDNDRENKCSDGISYLHDLSAIQLFVYLFAPLVDQIDESLFQTLKLENGLNIWSPLRNYKQPDLNCFTAPVKSKCRRVASNSRATDGIGVKSAQIYIGKGSSVEKLTMDPKDRSSFINGAFCPANILYPEESIDSEMTTSFGGTSLLDSNCKNHWIKSALCGGDNSVTVSCGHQTKLSPAPLARLSDICPLSTVSGDTVNLEVYCENCNSVVSNRSGELIGCSCYPVNTGPQVSKRNSWSLLHPRLGKLNFPIDWDYKNKIINETAACTQQTPSQGDDFLLASHLDLAVLRCLFCPKWSEPGVYWGLKYLHKRLLEISLELRMSEEQEKRLQNNFQKRSKSATCVKAEISDSFWQEPLGGKFDEDSNSNECYSELNSRNLVSQDPVNDLSASFPSSMWDRSMSISTMSIRPSKKIKMTDFKDRFTKISKFKKTEAEKDDDNFDLSSKLRNQMLITGLYGARLPSSPRQQRNIKIQDESVIPEELGDSGSDKDERRSSLPSDKLGIKLCPVYTEVEALLPPKKSRKTVTHKRQNGTKFKPITSKIKLTKYSDFSGCHENPIVQPEIQVSAEMDTKAPMFNLPDDPATALDPLPDFTLEKDSLSDEPGLCSSEVPLSSTKKTTSFFDDSPKQEKLSNEQQLQRNQEPIRKQVLRRSQSDTQINYQLIEELEEVSGSVHYIQGNGQMNYNVILKALHSLVNSHSSIRICEHIMHNMACLFDMGIFEKRIKKKKPDQENSSILSKRRNQLRNKKTKSNGQSPVAPPRFDAQRSSLSSSLQIRSSSSVGRRDRRVSMMINHGNYQNSRDFSAPSQSDEDGSDESRSKSAPPVRPSRFEKQLLSNKPKLERPTAEELNSGGMSNNDIAMEIIIKVIKILGCGYDHSCQNQSKERRTWPPGTNPNNTRLQTHECLLKLYKMHTRKFQSFLCRMAQDQSLSDIVEFLHAYTGFCNDPASLKPAGINSRNNYKNCFNQSVTGEGTRESEGVFIANFLEPLVERLVSSRKDLICQENFVLYSDIRQLLIYFKEVHGSTFRRVMLTGMLKVWRKQKRGRTGRNKVQILDPHLMRSGHSFPYDNEYLAGRSSSDLHNRTSSLSAALVATELLQQMAANNQNYKPGKKNIFKRYSSAVHNSTPDSNSLPIHVPIYRRGKKRESLCSQTYQIANDVREPDDNTGETVIDSVTVSVTDSRSRARSLVCDPDLDAAPPSPTKYVVNDPDSFSPPSPNRNSTSGANASASKGRTRNNNKGKEFQDAGSEASPTVSINTFPKSKDRKFIDPFTLKRGMAIFSFILDSFEPGMIPEPQLVASMLDLESPVLARACLLLELANFVARCNKGEWPSWMRFKFPGSYMNSSAIPMSGDHQFMNNTNKKIIFIQRQAGQMFHSWAEALGARLEYFLKIEQAADRFSNISEIQDEAKIRELQILDEEENFLDDSTVNPKGDSCPYALKSVVIQLLLAITTYLRETHQFLPKSRTISLKEPIYETSYNIDSTQDHKRVQEIPYRTTSPTQGGVELHSPDSDDQDSIESIVGEIGQINTEIHPAPGNRRISFAFSLHSSNNSLDQTDESGLKARKAPRTSAIEAFVPNYQVSCHPPTISSTASFLTPIRKISGSLERRKSVAGKNLLRKRRESGSFQRTNTVTRATKPETLGSLRAASHTRIGSIRYRKESSQSQVSTFTPESATVKEFSTSPVEVSTGYCSSIGISKCSELDNFSSHMPWMRVVTQFANKTNFVCNHVDFCHPDCYERQQRQCRRLLSAVKTVYSCDLSKRRKRDRKNSVATGRRESVDNCESSENSEEEGPYSASLGGSLAAALSHSVGERGSCDTDIDASMQLLLHRGVSESDEKKLSLFPRSRRKESMFGNHSPHRRKDSVPLFDKFLKSRTAAAAAAAAASSDELGLSFNIGEKGEPATNKHKSSVKEKSEDHPILLYLENYVFNLTHNCFNVVNKGALLLNEDIFADIMPVAWELLLENDPELVASAANVVILAAIKIPTLAQQLIFRELQHEDVNQRMSALLRFRSLWCCRFQFWQRLEDSASTQLKLPPPYIEFVLPSPTLGHPGSDVPDPSWSIRKCQSAEEVQLKQNEAAKTF------------------VTASTTRRK-QQQE-------MLEKA----VNAEEQRRKFA-----------RQEFH-----LTTCSILEKASFEVA-FSKEH------KDELGLEDDDDNGSCLTSPIVSNQPLQYAQCVFPSSLCAASIPIIHLLDDGDVNSDGVAVATIAEHVVWQCLVEDTTLFLRYILERLTRVTEKDELLYVLRKLIQRLPELPTQSAHALFNNLVGYIMFYVRTPSISAPESIAGALSLLWQIVPFVQNIYFKDLKQILRKEQVDPTLMVTANLPCAKQFNVFDEDVFVAQLVRLQDETKDYRFAEILKEALKDSNIPERDHHLYSLCDDRSNIIRNSSHYVRDFYFFKRNHIPKLRLKKMTPEDGNHLLQRNAFNLKFLEIGKVMFSYSILKHTPSNQNTNHIYFLHDELTKHPSFPRKALESEFSLYDSGSLGKQLYGMDMLHKISWCRLVSLLFERMPSSFPWTSDIHLFLNIFNGVLILHAEDTAMLRMCLAGCIQASQHFKMIFSVNGYLGIMPTILRVYSKNLHNLVLKKAIHFMCKQFYILHRTPFILQMFGSISNYIDFQGENSNFYKIKPHIIYDILRAISTDLEDNLNILQLLSCNKPLKALDFCYENENDSWSVLEAVTLCVTVIVYAPDSGRAKQMMIILQAILPLILRDLHQICIPPDFNSNTESCRKIEAQAIQQLAVSVKQLICTCDYLTRQTDKPFGKVGDEKCSFRVGGNYSQTQNSVVLEDQDESPYRLLEEGRFRKNTVVSNNCDEPSGGNSRHIVSAIAPHEAILQVSCDFYTSCHNRLNEMGEKHKALELLDQKSIMRLSELAQSIIKMIPNDINLLRSKALQRFMLEIPPFVDWDHESMKSCKALENLIYRLNRSMNKILKDNLSRRNLDWDSMTNLIKAVFLIVKRNKSVAFMKDVRQLMEYLRKLILLDSSPYAMNESLSSIQFSGRHDQTSPNHVTATGGDNTYSQATHTYNGIPPKFSAMVIKFFALMLQSLESTYKLKDFCERFDQRFGTTETILINYIENIIIPLLLCCGAGRKDSIQMSDENIYFIFDIILSSLNPIIHSNYQASRLPHTLIPN----------------QASTRFLTSTAAANTGEYMGGLASLVGLSGHTNKPYQHLNVGDSNQIRSSSVSHSEKSLKYGNDYLYRLSFLALKVAMICYPRHTLIQSRSISSVISDLGFKKQGGIHLWKFLDFIVTKRTPIFLSLIPFLRFK----------------------ASQIKCETQGEQAFQQVINQKFVGLHLPSPRCEATILKELAFDLRQIKDEWSGYFSQNQNQAVAVTIDAYVNKSSIRNIIPSLTNDSLTNSSICNQSVQGSVGFGNSKDNSRTTYLVRNAISRNSSRRINAKEGGNIICRYQQVQNPHRSDAILTVSSVDSLPSQATLEEDVPVKKYSGRLTRGETRNKKSVKLHWKQRPGSMVAGKSSSLAPDRPHHKQSTISGMSTPVGSAVAAAQAAQLYGSAAPYLRESLTRSRPEELIEMKGVQSFPVDETESSFSESSLLKRSHNIYRSRSEETEETNISPRDSLIPSLDSRHKVVIIESAYSADKANSEEALLTACGAGVTLAESESSNASVTEYSSLIRLKPPNE 3766 The following BLAST results are available for this feature:
BLAST of Protein unc-80 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein unc-80 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein unc-80 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein unc-80 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of Protein unc-80 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein unc-80 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of Protein unc-80 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of Protein unc-80 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein unc-80 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of Protein unc-80 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Protein unc-80 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protein unc-80 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Protein unc-80 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of Protein unc-80 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033709 ID=SMED30033709|Name=Protein unc-80|organism=Schmidtea mediterranea sexual|type=transcript|length=11702bpback to top protein sequence of SMED30033709-orf-1 >SMED30033709-orf-1 ID=SMED30033709-orf-1|Name=SMED30033709-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=3858bp MTNYAKPSKAFDESNKSNYIPLQIQSFLLTQTNSFFLNKNTRDNACISLEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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