chromobox protein homolog 1

Overview


Name	chromobox protein homolog 1
Smed ID	SMED30033701
Length (bp)	1120

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of chromobox protein homolog 1 (SMED30033701) t-SNE clustered cells

Violin plots show distribution of expression levels for chromobox protein homolog 1 (SMED30033701) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of chromobox protein homolog 1 (SMED30033701) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for chromobox protein homolog 1 (SMED30033701) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30033701

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 18

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
parenchyma	SMED30033701	h1SMcG0004366	JN216839	smed_ncbi_20240424	PMID:23629965 Zeng et al., 2013
X1 cell	SMED30033701	h1SMcG0004366	SmedASXL_009807	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
Smed sexual biotype	SMED30033701	h1SMcG0004366	Contig137	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30033701	h1SMcG0004366	Contig137	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
pharynx	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30033701	h1SMcG0004366	dd_Smed_v4_4855_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
secretory system	SMED30033701	h1SMcG0004366	dd_Smed_v6_4855_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
neoblast	SMED30033701	h1SMcG0004366	SMED_09295_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30033701	h1SMcG0004366	SMED_09295_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Human
Match: CBX1 (chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551])

HSP 1 Score: 72.4034 bits (176), Expect = 7.364e-20
Identity = 30/59 (50.85%), Postives = 41/59 (69.49%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  112 GFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 170

HSP 2 Score: 44.669 bits (104), Expect = 7.364e-20
Identity = 21/45 (46.67%), Postives = 27/45 (60.00%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQ 242
            GK  YLLKWK +    N+WEPEE+L+C  LI  F ++ K    T 
Sbjct:   34 GKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETD 78

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Human
Match: CBX1 (chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551])

HSP 1 Score: 72.4034 bits (176), Expect = 7.589e-20
Identity = 30/59 (50.85%), Postives = 41/59 (69.49%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  112 GFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 170

HSP 2 Score: 44.669 bits (104), Expect = 7.589e-20
Identity = 21/45 (46.67%), Postives = 27/45 (60.00%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQ 242
            GK  YLLKWK +    N+WEPEE+L+C  LI  F ++ K    T 
Sbjct:   34 GKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETD 78

[Close]

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  112 GFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 170

HSP 2 Score: 44.669 bits (104), Expect = 7.589e-20
Identity = 21/45 (46.67%), Postives = 27/45 (60.00%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQ 242
            GK  YLLKWK +    N+WEPEE+L+C  LI  F ++ K    T 
Sbjct:   34 GKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETD 78

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Human
Match: CBX3 (chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553])

HSP 1 Score: 67.781 bits (164), Expect = 1.564e-19
Identity = 29/63 (46.03%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL P+ I G T  +  + F++KW   DE D+V A +AN+KCPQ+VI FYE   ++
Sbjct:  112 DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW 174

HSP 2 Score: 48.521 bits (114), Expect = 1.564e-19
Identity = 22/45 (48.89%), Postives = 30/45 (66.67%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            VEK++     NGK  Y LKWK +  + N+WEPEE+L+C  LI+ F
Sbjct:   32 VEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF 76

[Close]

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL P+ I G T  +  + F++KW   DE D+V A +AN+KCPQ+VI FYE   ++
Sbjct:  112 DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW 174

HSP 2 Score: 48.521 bits (114), Expect = 1.564e-19
Identity = 22/45 (48.89%), Postives = 30/45 (66.67%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            VEK++     NGK  Y LKWK +  + N+WEPEE+L+C  LI+ F
Sbjct:   32 VEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF 76

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Fly
Match: HP1b (gene:FBgn0030082 transcript:FBtr0071284)

HSP 1 Score: 67.0106 bits (162), Expect = 1.104e-20
Identity = 27/59 (45.76%), Postives = 39/59 (66.10%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF+RGL+   I G T  +  + F++KW G D  D+VPA  AN +CPQ+VI+FYE   ++
Sbjct:   94 GFERGLEASKILGATDSSGHLMFLMKWKGSDHADLVPAKLANTRCPQVVIQFYEERLTW 152

HSP 2 Score: 51.9878 bits (123), Expect = 1.104e-20
Identity = 32/89 (35.96%), Postives = 46/89 (51.69%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK-----LKEFTQNFQLPMTIKVPVRIGFLLNATFYYYRLL 326
            VE++      NG+  Y LKWK Y  S N+WEP E+L+C  LI NF ++LK      K+       P +I+   R  FL + T    +L+
Sbjct:    6 VERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANFEESLKNNKKETKKRLSTSSTPESIRS-KRKSFLEDDTEEQKKLI 93

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Fly
Match: HP1b (gene:FBgn0030082 transcript:FBtr0309871)

HSP 1 Score: 67.0106 bits (162), Expect = 1.104e-20
Identity = 27/59 (45.76%), Postives = 39/59 (66.10%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF+RGL+   I G T  +  + F++KW G D  D+VPA  AN +CPQ+VI+FYE   ++
Sbjct:   94 GFERGLEASKILGATDSSGHLMFLMKWKGSDHADLVPAKLANTRCPQVVIQFYEERLTW 152

HSP 2 Score: 51.9878 bits (123), Expect = 1.104e-20
Identity = 32/89 (35.96%), Postives = 46/89 (51.69%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK-----LKEFTQNFQLPMTIKVPVRIGFLLNATFYYYRLL 326
            VE++      NG+  Y LKWK Y  S N+WEP E+L+C  LI NF ++LK      K+       P +I+   R  FL + T    +L+
Sbjct:    6 VERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANFEESLKNNKKETKKRLSTSSTPESIRS-KRKSFLEDDTEEQKKLI 93

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Fly
Match: HP1b (gene:FBgn0030082 transcript:FBtr0301805)

HSP 1 Score: 67.0106 bits (162), Expect = 1.104e-20
Identity = 27/59 (45.76%), Postives = 39/59 (66.10%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF+RGL+   I G T  +  + F++KW G D  D+VPA  AN +CPQ+VI+FYE   ++
Sbjct:   94 GFERGLEASKILGATDSSGHLMFLMKWKGSDHADLVPAKLANTRCPQVVIQFYEERLTW 152

HSP 2 Score: 51.9878 bits (123), Expect = 1.104e-20
Identity = 32/89 (35.96%), Postives = 46/89 (51.69%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK-----LKEFTQNFQLPMTIKVPVRIGFLLNATFYYYRLL 326
            VE++      NG+  Y LKWK Y  S N+WEP E+L+C  LI NF ++LK      K+       P +I+   R  FL + T    +L+
Sbjct:    6 VERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANFEESLKNNKKETKKRLSTSSTPESIRS-KRKSFLEDDTEEQKKLI 93

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Fly
Match: HP6 (gene:FBgn0031613 transcript:FBtr0077444)

HSP 1 Score: 65.4698 bits (158), Expect = 4.751e-13
Identity = 28/61 (45.90%), Postives = 38/61 (62.30%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 523
            GFD GL+P  I G    +  + F+++W GCDE  +VPA   NV+CPQ+VI FYE    F +
Sbjct:   19 GFDLGLEPLRILGACNWSGKLTFLMQWKGCDEAGLVPAEVLNVRCPQMVISFYEERIVFTD 79

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Fly
Match: HP1e (gene:FBgn0037675 transcript:FBtr0082016)

HSP 1 Score: 45.8246 bits (107), Expect = 2.336e-10
Identity = 23/60 (38.33%), Postives = 36/60 (60.00%), Query Frame = 2

Query:  344 FDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 523
            F+ G   Q I    K N  I F+I++   D+  VVP+  A V+ PQ+V++FYEN+ +F +
Sbjct:  108 FNHGFTAQEILKGAKNNGEISFLIRFWHLDQPQVVPSGIAYVEIPQMVLKFYENHCNFHD 167

HSP 2 Score: 38.5058 bits (88), Expect = 2.336e-10
Identity = 18/52 (34.62%), Postives = 28/52 (53.85%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLK 230
            VE+I+   +  G+  YL+KW +Y    N+WE    L+C +LI +      LK
Sbjct:   29 VERILDRRHYMGQLQYLVKWLDYSDEDNTWESAADLDCHSLIDSIESQKSLK 80

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Zebrafish
Match: cbx1b (chromobox homolog 1b (HP1 beta homolog Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040625-68])

HSP 1 Score: 72.0182 bits (175), Expect = 3.942e-20
Identity = 30/59 (50.85%), Postives = 40/59 (67.80%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  130 GFARGLDPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 188

HSP 2 Score: 45.4394 bits (106), Expect = 3.942e-20
Identity = 20/42 (47.62%), Postives = 27/42 (64.29%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKE 233
            GK  YLLKWK +    N+WEP+E+L+C  LI  F ++ K  E
Sbjct:   61 GKVEYLLKWKGFSDEDNTWEPDENLDCPDLIAEFLQSQKTAE 102

[Close]

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  130 GFARGLDPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 188

HSP 2 Score: 45.4394 bits (106), Expect = 3.942e-20
Identity = 20/42 (47.62%), Postives = 27/42 (64.29%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKE 233
            GK  YLLKWK +    N+WEP+E+L+C  LI  F ++ K  E
Sbjct:   61 GKVEYLLKWKGFSDEDNTWEPDENLDCPDLIAEFLQSQKTAE 102

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Zebrafish
Match: cbx3a (chromobox homolog 3a (HP1 gamma homolog, Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-1158])

HSP 1 Score: 69.707 bits (169), Expect = 6.331e-20
Identity = 28/63 (44.44%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF R L+P+ I G T  +  + F++KW   DE D+VPA +AN +CPQ+VI FYE   ++
Sbjct:  103 DKPRGFARNLEPERIIGATDSSGELMFLMKWKDSDEADLVPAREANTRCPQIVIAFYEERLTW 165

HSP 2 Score: 47.3654 bits (111), Expect = 6.331e-20
Identity = 22/50 (44.00%), Postives = 32/50 (64.00%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK 224
            VEK++     NGK  + LKWK +  + N+WEPEE+L+C  LI  F ++ K
Sbjct:   21 VEKVMDQRVVNGKVEFFLKWKGFTDADNTWEPEENLDCPELIAAFLESQK 70

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Zebrafish
Match: cbx3a (chromobox homolog 3a (HP1 gamma homolog, Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-1158])

HSP 1 Score: 69.707 bits (169), Expect = 6.431e-20
Identity = 28/63 (44.44%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF R L+P+ I G T  +  + F++KW   DE D+VPA +AN +CPQ+VI FYE   ++
Sbjct:  106 DKPRGFARNLEPERIIGATDSSGELMFLMKWKDSDEADLVPAREANTRCPQIVIAFYEERLTW 168

HSP 2 Score: 47.3654 bits (111), Expect = 6.431e-20
Identity = 22/50 (44.00%), Postives = 32/50 (64.00%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK 224
            VEK++     NGK  + LKWK +  + N+WEPEE+L+C  LI  F ++ K
Sbjct:   24 VEKVMDQRVVNGKVEFFLKWKGFTDADNTWEPEENLDCPELIAAFLESQK 73

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Zebrafish
Match: cbx1a (chromobox homolog 1a (HP1 beta homolog Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-4945])

HSP 1 Score: 74.7146 bits (182), Expect = 1.173e-19
Identity = 31/64 (48.44%), Postives = 42/64 (65.62%), Query Frame = 2

Query:  326 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            +D   GF RGL P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  134 QDKPRGFARGLDPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 197

HSP 2 Score: 41.5874 bits (96), Expect = 1.173e-19
Identity = 16/34 (47.06%), Postives = 23/34 (67.65%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            G+  YLLKWK +    N+WEPE++L+C  LI  +
Sbjct:   63 GRVEYLLKWKGFSEEDNTWEPEDNLDCPDLIAEY 96

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Xenopus
Match: stab2 (stabilin 2 [Source:Xenbase;Acc:XB-GENE-491156])

HSP 1 Score: 72.4034 bits (176), Expect = 3.864e-21
Identity = 31/63 (49.21%), Postives = 41/63 (65.08%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  117 DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVPAKEANVKCPQVVIAFYEERLTW 179

HSP 2 Score: 49.2914 bits (116), Expect = 3.864e-21
Identity = 23/45 (51.11%), Postives = 30/45 (66.67%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            VEK++     NGK  Y LKWK +  S N+WEPEE+L+C  LI+ F
Sbjct:   36 VEKVLDRRVVNGKVEYYLKWKGFTDSDNTWEPEENLDCPELIEAF 80

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Xenopus
Match: zbtb11 (zinc finger and BTB domain containing 11 [Source:Xenbase;Acc:XB-GENE-988913])

HSP 1 Score: 72.7886 bits (177), Expect = 5.184e-20
Identity = 30/59 (50.85%), Postives = 41/59 (69.49%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  111 GFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 169

HSP 2 Score: 45.0542 bits (105), Expect = 5.184e-20
Identity = 20/39 (51.28%), Postives = 26/39 (66.67%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK 224
            GK  YLLKWK +    N+WEPEE+L+C  LI  F ++ K
Sbjct:   34 GKVEYLLKWKGFSDDDNTWEPEENLDCPDLIAEFLQSQK 72

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Xenopus
Match: tnfaip6 (TNF alpha induced protein 6 [Source:Xenbase;Acc:XB-GENE-988687])

HSP 1 Score: 69.707 bits (169), Expect = 1.597e-18
Identity = 31/63 (49.21%), Postives = 42/63 (66.67%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D A GF+RGL+P+ I G T     + F++KW   DE D+V A +ANVKCPQ+VI FYE   ++
Sbjct:  121 DIARGFERGLEPEKIIGATDSCGELMFLMKWKDSDEADLVLAKEANVKCPQIVIAFYEERLTW 183

HSP 2 Score: 43.1282 bits (100), Expect = 1.597e-18
Identity = 20/50 (40.00%), Postives = 29/50 (58.00%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK 224
            VEK++      G+  +LLKWK +    N+WEP+ +L+C  LI  F K  K
Sbjct:   39 VEKVLDRRVVKGQVEFLLKWKGFSEEHNTWEPDRNLDCPELISEFMKKYK 88

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Xenopus
Match: ENSXETT00000037867.1 (chromodomain Y like [Source:NCBI gene;Acc:100491952])

HSP 1 Score: 50.0618 bits (118), Expect = 4.473e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 3

Query:   63 EVIEVEKII-AVSNRNGKRCYLLKWKNYDSSLNSWEPEEHL-NCGALIKNFHK 215
            E+ EVE+I+    N+ GK  YL+ WK YDS  ++WEPE+HL NC   I  F++
Sbjct:    5 ELYEVEQIVDKRKNKKGKIEYLVHWKGYDSGDDTWEPEQHLVNCEEYIHEFNR 57

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Xenopus
Match: ENSXETT00000025504.1 (chromodomain Y like [Source:NCBI gene;Acc:100491952])

HSP 1 Score: 50.0618 bits (118), Expect = 4.504e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 3

Query:   63 EVIEVEKII-AVSNRNGKRCYLLKWKNYDSSLNSWEPEEHL-NCGALIKNFHK 215
            E+ EVE+I+    N+ GK  YL+ WK YDS  ++WEPE+HL NC   I  F++
Sbjct:    5 ELYEVEQIVDKRKNKKGKIEYLVHWKGYDSGDDTWEPEQHLVNCEEYIHEFNR 57

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Mouse
Match: Cbx1 (chromobox 1 [Source:MGI Symbol;Acc:MGI:105369])

HSP 1 Score: 72.4034 bits (176), Expect = 5.501e-20
Identity = 30/59 (50.85%), Postives = 41/59 (69.49%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  112 GFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 170

HSP 2 Score: 44.669 bits (104), Expect = 5.501e-20
Identity = 21/45 (46.67%), Postives = 27/45 (60.00%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQ 242
            GK  YLLKWK +    N+WEPEE+L+C  LI  F ++ K    T 
Sbjct:   34 GKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETD 78

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Mouse
Match: Cbx3 (chromobox 3 [Source:MGI Symbol;Acc:MGI:108515])

HSP 1 Score: 67.781 bits (164), Expect = 1.133e-19
Identity = 29/63 (46.03%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL P+ I G T  +  + F++KW   DE D+V A +AN+KCPQ+VI FYE   ++
Sbjct:  112 DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW 174

HSP 2 Score: 48.521 bits (114), Expect = 1.133e-19
Identity = 22/45 (48.89%), Postives = 30/45 (66.67%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            VEK++     NGK  Y LKWK +  + N+WEPEE+L+C  LI+ F
Sbjct:   32 VEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF 76

[Close]

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL P+ I G T  +  + F++KW   DE D+V A +AN+KCPQ+VI FYE   ++
Sbjct:  112 DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW 174

HSP 2 Score: 48.521 bits (114), Expect = 1.133e-19
Identity = 22/45 (48.89%), Postives = 30/45 (66.67%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            VEK++     NGK  Y LKWK +  + N+WEPEE+L+C  LI+ F
Sbjct:   32 VEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF 76

[Close]

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL P+ I G T  +  + F++KW   DE D+V A +AN+KCPQ+VI FYE   ++
Sbjct:  112 DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW 174

HSP 2 Score: 48.521 bits (114), Expect = 1.133e-19
Identity = 22/45 (48.89%), Postives = 30/45 (66.67%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            VEK++     NGK  Y LKWK +  + N+WEPEE+L+C  LI+ F
Sbjct:   32 VEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF 76

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Mouse
Match: Cbx5 (chromobox 5 [Source:MGI Symbol;Acc:MGI:109372])

HSP 1 Score: 68.9366 bits (167), Expect = 2.129e-19
Identity = 31/63 (49.21%), Postives = 42/63 (66.67%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D A GF+RGL+P+ I G T     + F++KW   DE D+V A +ANVKCPQ+VI FYE   ++
Sbjct:  112 DIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTW 174

HSP 2 Score: 46.2098 bits (108), Expect = 2.129e-19
Identity = 25/58 (43.10%), Postives = 34/58 (58.62%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNL-KLKEFTQN 245
            VEK++      G+  YLLKWK +    N+WEPE++L+C  LI  F K   K+KE   N
Sbjct:   22 VEKVLDRRMVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMKEGENN 79

[Close]

BLAST of chromobox protein homolog 1 vs. UniProt/SwissProt
Match: sp|P23198|CBX3_MOUSE (Chromobox protein homolog 3 OS=Mus musculus OX=10090 GN=Cbx3 PE=1 SV=2)

HSP 1 Score: 67.3958 bits (163), Expect = 2.647e-19
Identity = 29/63 (46.03%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL P+ I G T  +  + F++KW   DE D+V A +AN+KCPQ+VI FYE   ++
Sbjct:  112 DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW 174

HSP 2 Score: 50.0618 bits (118), Expect = 2.647e-19
Identity = 22/45 (48.89%), Postives = 31/45 (68.89%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            VEK++     NGK  Y LKWK +  + N+WEPEE+L+C  LI++F
Sbjct:   32 VEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEDF 76

[Close]

BLAST of chromobox protein homolog 1 vs. UniProt/SwissProt
Match: sp|P83917|CBX1_MOUSE (Chromobox protein homolog 1 OS=Mus musculus OX=10090 GN=Cbx1 PE=1 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 3.302e-19
Identity = 30/59 (50.85%), Postives = 41/59 (69.49%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  112 GFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 170

HSP 2 Score: 44.669 bits (104), Expect = 3.302e-19
Identity = 21/45 (46.67%), Postives = 27/45 (60.00%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQ 242
            GK  YLLKWK +    N+WEPEE+L+C  LI  F ++ K    T 
Sbjct:   34 GKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETD 78

[Close]

BLAST of chromobox protein homolog 1 vs. UniProt/SwissProt
Match: sp|P83916|CBX1_HUMAN (Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 3.302e-19
Identity = 30/59 (50.85%), Postives = 41/59 (69.49%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  112 GFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 170

HSP 2 Score: 44.669 bits (104), Expect = 3.302e-19
Identity = 21/45 (46.67%), Postives = 27/45 (60.00%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQ 242
            GK  YLLKWK +    N+WEPEE+L+C  LI  F ++ K    T 
Sbjct:   34 GKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETD 78

[Close]

BLAST of chromobox protein homolog 1 vs. UniProt/SwissProt
Match: sp|Q5R6X7|CBX3_PONAB (Chromobox protein homolog 3 OS=Pongo abelii OX=9601 GN=CBX3 PE=2 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 6.805e-19
Identity = 29/63 (46.03%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL P+ I G T  +  + F++KW   DE D+V A +AN+KCPQ+VI FYE   ++
Sbjct:  112 DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW 174

HSP 2 Score: 48.521 bits (114), Expect = 6.805e-19
Identity = 22/45 (48.89%), Postives = 30/45 (66.67%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            VEK++     NGK  Y LKWK +  + N+WEPEE+L+C  LI+ F
Sbjct:   32 VEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF 76

[Close]

BLAST of chromobox protein homolog 1 vs. UniProt/SwissProt
Match: sp|Q13185|CBX3_HUMAN (Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4)

HSP 1 Score: 67.781 bits (164), Expect = 6.805e-19
Identity = 29/63 (46.03%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL P+ I G T  +  + F++KW   DE D+V A +AN+KCPQ+VI FYE   ++
Sbjct:  112 DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW 174

HSP 2 Score: 48.521 bits (114), Expect = 6.805e-19
Identity = 22/45 (48.89%), Postives = 30/45 (66.67%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            VEK++     NGK  Y LKWK +  + N+WEPEE+L+C  LI+ F
Sbjct:   32 VEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAF 76

[Close]

BLAST of chromobox protein homolog 1 vs. TrEMBL
Match: M9NNX2 (Heterochromatin protein 1-like protein 2 OS=Schmidtea mediterranea OX=79327 GN=HP1-2 PE=2 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 5.740e-70
Identity = 73/74 (98.65%), Postives = 74/74 (100.00%), Query Frame = 3

Query:   57 MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVPV 278
            MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVP+
Sbjct:    1 MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVPI 74

HSP 2 Score: 141.739 bits (356), Expect = 5.740e-70
Identity = 66/66 (100.00%), Postives = 66/66 (100.00%), Query Frame = 2

Query:  326 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 523
            KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE
Sbjct:   76 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 141

[Close]

BLAST of chromobox protein homolog 1 vs. TrEMBL
Match: A0A504YE48 (Chromobox protein 1 (Heterochromatin protein 1 beta) OS=Fasciola gigantica OX=46835 GN=FGIG_04052 PE=4 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.434e-24
Identity = 41/64 (64.06%), Postives = 47/64 (73.44%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFE 520
            D  YGFDRGL P  I  VTKK+D +YF+IKW G  E DVVPA QAN +CPQLVIRFYE+   F+
Sbjct:   78 DEPYGFDRGLAPDFISMVTKKDDELYFLIKWKGRQECDVVPAAQANTRCPQLVIRFYESILHFK 141

HSP 2 Score: 52.7582 bits (125), Expect = 1.434e-24
Identity = 26/69 (37.68%), Postives = 43/69 (62.32%), Query Frame = 3

Query:   69 IEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVP 275
             EVE+++ V + NGK  Y +KWK +   +N+WEP  +LNC +L+K F   L  + F++     +T++VP
Sbjct:   14 FEVEELVDVRHVNGKPEYFIKWKGHPPEMNTWEPYSNLNCPSLLKKF---LAQRSFSRQ----VTVEVP 75

[Close]

BLAST of chromobox protein homolog 1 vs. TrEMBL
Match: A0A4E0RD81 (Chromobox protein 1 (Heterochromatin protein 1 beta) OS=Fasciola hepatica OX=6192 GN=D915_004599 PE=4 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.469e-24
Identity = 41/64 (64.06%), Postives = 47/64 (73.44%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFE 520
            D  YGFDRGL P  I  VTKK+D +YF+IKW G  E DVVPA QAN +CPQLVIRFYE+   F+
Sbjct:   78 DEPYGFDRGLAPDFISMVTKKDDELYFLIKWKGRQECDVVPAAQANTRCPQLVIRFYESILHFK 141

HSP 2 Score: 52.7582 bits (125), Expect = 1.469e-24
Identity = 26/69 (37.68%), Postives = 43/69 (62.32%), Query Frame = 3

Query:   69 IEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVP 275
             EVE+++ V + NGK  Y +KWK +   +N+WEP  +LNC +L+K F   L  + F++     +T++VP
Sbjct:   14 FEVEELVDVRHVNGKPEYFIKWKGHPPEMNTWEPYSNLNCPSLLKKF---LAQRSFSRQ----VTVEVP 75

[Close]

BLAST of chromobox protein homolog 1 vs. TrEMBL
Match: J3JTC0 (Uncharacterized protein OS=Dendroctonus ponderosae OX=77166 GN=109533696 PE=2 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 1.863e-24
Identity = 34/60 (56.67%), Postives = 45/60 (75.00%), Query Frame = 2

Query:  338 YGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            +GFDRGL+P+ I G T  +  + F++KW G DE D+VPA QANVKCPQ+VI+FYE   S+
Sbjct:  104 HGFDRGLQPEKIIGATNSSGPLLFLMKWVGTDEADLVPATQANVKCPQVVIKFYEERLSW 163

HSP 2 Score: 60.077 bits (144), Expect = 1.863e-24
Identity = 28/57 (49.12%), Postives = 37/57 (64.91%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQN 245
            VEKII    +NG + YLLKW  YD   N+WEPE +L+C +LIK F  +  +KE  +N
Sbjct:   21 VEKIIDCRIKNGVKEYLLKWIGYDDKDNTWEPESNLDCPSLIKTFEADRAVKEAEKN 77

[Close]

BLAST of chromobox protein homolog 1 vs. TrEMBL
Match: A0A224YJX0 (Chromobox protein 3 OS=Rhipicephalus zambeziensis OX=60191 PE=4 SV=1)

HSP 1 Score: 77.411 bits (189), Expect = 3.863e-24
Identity = 33/60 (55.00%), Postives = 42/60 (70.00%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFE 520
            GFDRGL P  I G T  +  + F+IKW  CDE D+VPA  ANV+CPQ+VIRFYE   +++
Sbjct:  108 GFDRGLDPDRIIGATDSSGELMFLIKWKDCDEADIVPARVANVRCPQVVIRFYEERLTWD 167

HSP 2 Score: 63.929 bits (154), Expect = 3.863e-24
Identity = 31/69 (44.93%), Postives = 40/69 (57.97%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVPVR 281
            VEKI+    R GK  YLLKWK Y  S N+WEPEE+L+C  LI  F +  K K  +Q+ ++      P R
Sbjct:   27 VEKILDRRVRQGKVEYLLKWKGYGDSENTWEPEENLDCPGLIAQFEEKRKQKAESQSTKMKDDADAPSR 95

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Cavefish
Match: cbx1a (chromobox protein homolog 1-like [Source:NCBI gene;Acc:103037352])

HSP 1 Score: 71.633 bits (174), Expect = 1.284e-19
Identity = 30/64 (46.88%), Postives = 42/64 (65.62%), Query Frame = 2

Query:  326 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            ++   GF RGL P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  134 QEKPRGFARGLDPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 197

HSP 2 Score: 44.2838 bits (103), Expect = 1.284e-19
Identity = 18/39 (46.15%), Postives = 26/39 (66.67%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK 224
            G+  +LLKWK +    N+WEPE++L+C  LI  F +N K
Sbjct:   63 GRTEFLLKWKGFTDEDNTWEPEDNLDCPDLIAEFMQNYK 101

[Close]

Query:  326 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            ++   GF RGL P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  134 QEKPRGFARGLDPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 197

HSP 2 Score: 44.2838 bits (103), Expect = 1.284e-19
Identity = 18/39 (46.15%), Postives = 26/39 (66.67%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK 224
            G+  +LLKWK +    N+WEPE++L+C  LI  F +N K
Sbjct:   63 GRTEFLLKWKGFTDEDNTWEPEDNLDCPDLIAEFMQNYK 101

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Cavefish
Match: cbx5 (chromobox 5 [Source:NCBI gene;Acc:103047453])

HSP 1 Score: 67.781 bits (164), Expect = 1.356e-18
Identity = 30/63 (47.62%), Postives = 41/63 (65.08%), Query Frame = 2

Query:  335 AYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 523
            A GF+RGL+P+ I G T     + F++KW   DE D+V A +AN KCPQ+VI FYE   ++ E
Sbjct:  124 ARGFERGLEPEKIIGATDSCGDLMFLMKWKDSDEADLVLAKEANHKCPQIVIAFYEERLTWHE 186

HSP 2 Score: 44.2838 bits (103), Expect = 1.356e-18
Identity = 21/50 (42.00%), Postives = 29/50 (58.00%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK 224
            VEK++      G+  Y LKWK +    N+WEPE++L+C  LI  F K  K
Sbjct:   43 VEKVLDRRVVKGRVEYFLKWKGFTDKHNTWEPEKNLDCPDLISEFMKTYK 92

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Cavefish
Match: cbx3a (chromobox protein homolog 3-like [Source:NCBI gene;Acc:103046426])

HSP 1 Score: 67.3958 bits (163), Expect = 2.379e-18
Identity = 27/63 (42.86%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            +   GF R L+P+ I G T  +  + F++KW   DE D+VPA +AN +CPQ+VI FYE   ++
Sbjct:  107 EKPRGFARNLEPERIIGATDSSGELMFLMKWKDSDEADLVPAREANTRCPQVVIAFYEERLTW 169

HSP 2 Score: 44.2838 bits (103), Expect = 2.379e-18
Identity = 18/35 (51.43%), Postives = 24/35 (68.57%), Query Frame = 3

Query:  105 NGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            NGK  + LKWK +  + N+WEPEE+L+C  LI  F
Sbjct:   35 NGKVEFFLKWKGFPDTDNTWEPEENLDCPELISAF 69

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Cavefish
Match: cbx3a (chromobox protein homolog 3-like [Source:NCBI gene;Acc:103046426])

HSP 1 Score: 67.0106 bits (162), Expect = 3.668e-18
Identity = 27/63 (42.86%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            +   GF R L+P+ I G T  +  + F++KW   DE D+VPA +AN +CPQ+VI FYE   ++
Sbjct:  114 EKPRGFARNLEPERIIGATDSSGELMFLMKWKDSDEADLVPAREANTRCPQVVIAFYEERLTW 176

HSP 2 Score: 43.8986 bits (102), Expect = 3.668e-18
Identity = 18/35 (51.43%), Postives = 24/35 (68.57%), Query Frame = 3

Query:  105 NGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            NGK  + LKWK +  + N+WEPEE+L+C  LI  F
Sbjct:   42 NGKVEFFLKWKGFPDTDNTWEPEENLDCPELISAF 76

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Sea Lamprey
Match: CBX1 (chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551])

HSP 1 Score: 74.7146 bits (182), Expect = 1.045e-21
Identity = 31/59 (52.54%), Postives = 41/59 (69.49%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL P+ I G T  +  + F++KW G DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  136 GFARGLDPERIIGATDSSGELMFLMKWKGSDEADLVPAKEANVKCPQIVISFYEERLTW 194

HSP 2 Score: 45.8246 bits (107), Expect = 1.045e-21
Identity = 21/41 (51.22%), Postives = 27/41 (65.85%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLK 230
            GK  YLLKWK +    N+WEP+E+L+C  LI  F +N K K
Sbjct:   55 GKVEYLLKWKGFGDEDNTWEPDENLDCPDLISEFLENYKNK 95

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Sea Lamprey
Match: CBX1 (chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551])

HSP 1 Score: 71.633 bits (174), Expect = 1.669e-20
Identity = 29/59 (49.15%), Postives = 40/59 (67.80%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T  +  + F++KW G DE D+VPA +AN  CPQ+VI FYE   ++
Sbjct:  114 GFSRGLEPERIIGATDSSGELMFLMKWYGSDEADLVPAKEANTSCPQIVISFYEERLTW 172

HSP 2 Score: 44.669 bits (104), Expect = 1.669e-20
Identity = 22/53 (41.51%), Postives = 30/53 (56.60%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKE 233
            VEK++      GK  Y LKWK +    N+WEPEE+L+C  LI  +    K K+
Sbjct:   23 VEKVMDRRVVKGKVEYFLKWKGFTEEDNTWEPEENLDCPDLISEYLGTSKGKQ 75

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009664.1 (pep scaffold:Pmarinus_7.0:GL477881:602658:605312:-1 gene:ENSPMAG00000008728.1 transcript:ENSPMAT00000009664.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.7146 bits (182), Expect = 5.676e-16
Identity = 30/59 (50.85%), Postives = 43/59 (72.88%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T  +  + F++KW GC+E D+VPA +AN+KCPQ+VI FYE   ++
Sbjct:  138 GFVRGLEPEKIIGATDSSGELMFLMKWKGCEEADLVPAKEANLKCPQVVISFYEERLTW 196

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Sea Lamprey
Match: CBX1 (chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551])

HSP 1 Score: 73.1738 bits (178), Expect = 1.826e-15
Identity = 30/63 (47.62%), Postives = 42/63 (66.67%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            D   GF RGL+P+ I G T  +  + F++KW   DE D+VPA +AN+KCPQ+VI FYE   ++
Sbjct:  115 DRIRGFTRGLEPERIIGATDSSGELMFLMKWRDSDEADLVPAKEANLKCPQVVISFYEERLTW 177

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Sea Lamprey
Match: CBX1 (chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551])

HSP 1 Score: 67.0106 bits (162), Expect = 2.968e-13
Identity = 29/59 (49.15%), Postives = 41/59 (69.49%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF  GL+ + I G T  +  + F++KW G DE D+VPA +ANVKCPQ+VI+FYE   ++
Sbjct:  134 GFAGGLEAERIVGATDCSGELMFLMKWKGLDETDLVPAKEANVKCPQVVIKFYEERVTW 192

HSP 2 Score: 52.7582 bits (125), Expect = 1.873e-8
Identity = 25/52 (48.08%), Postives = 34/52 (65.38%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLK 230
            VEK++      GK  YLLKWK +    N+WEPE+HL+C  LI ++  +LKLK
Sbjct:   31 VEKVLDRRVVKGKVEYLLKWKGFSHGDNTWEPEDHLDCPELINHYLDSLKLK 82

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Nematostella
Match: EDO48908 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHT1])

HSP 1 Score: 53.9138 bits (128), Expect = 1.372e-8
Identity = 23/64 (35.94%), Postives = 37/64 (57.81%), Query Frame = 2

Query:  326 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            KD       G +   I G T+ +  I+F+I+W   D  D++P+  AN+K PQ+VI+FYE   ++
Sbjct:  132 KDDVDPIAEGWEADTILGATEVDGQIHFLIQWKSTDRADLIPSKVANLKWPQIVIKFYEERVTW 195

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Nematostella
Match: EDO27150 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TA22])

HSP 1 Score: 43.8986 bits (102), Expect = 2.970e-6
Identity = 20/55 (36.36%), Postives = 31/55 (56.36%), Query Frame = 3

Query:   66 VIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLK 230
            +   E I+    R+GK  Y +KWK Y    N+WEPEE++    L+K + + L L+
Sbjct:   10 IYAAETILKERVRDGKVWYFIKWKGYSQRYNTWEPEENVLDPRLLKAYQERLALR 64

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Medaka
Match: CBX1 (chromobox protein homolog 1 [Source:NCBI gene;Acc:101170765])

HSP 1 Score: 75.485 bits (184), Expect = 5.557e-20
Identity = 31/63 (49.21%), Postives = 43/63 (68.25%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            + A GF RGL+P+ I G T  +  + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  103 EKARGFGRGLQPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 165

HSP 2 Score: 41.2022 bits (95), Expect = 5.557e-20
Identity = 17/34 (50.00%), Postives = 23/34 (67.65%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF 209
            GK  +LLKWK +    N+WEPEE+L+C  LI  +
Sbjct:   31 GKVEFLLKWKGFSEEDNTWEPEENLDCPDLIAEY 64

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Medaka
Match: cbx3a (chromobox protein homolog 3 [Source:NCBI gene;Acc:100049459])

HSP 1 Score: 67.781 bits (164), Expect = 1.214e-19
Identity = 27/63 (42.86%), Postives = 40/63 (63.49%), Query Frame = 2

Query:  329 DHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            +   GF R L+P+ I G T  +  + F++KW   DE D+VPA +AN +CPQ+VI FYE   ++
Sbjct:  103 EKPRGFARNLEPERIIGATDSSGELMFLMKWKDSDEADLVPAREANTRCPQVVISFYEERLTW 165

HSP 2 Score: 47.7506 bits (112), Expect = 1.214e-19
Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNF---HKNLKLK 230
            VEK++     NGK  + LKWK +  + N+WEPEE+L+C  LI  F    KN+K K
Sbjct:   25 VEKVLDQRLVNGKVEFYLKWKGFTDADNTWEPEENLDCPELISAFLESQKNIKEK 79

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Medaka
Match: CBX1 (chromobox 1 [Source:NCBI gene;Acc:101155967])

HSP 1 Score: 71.633 bits (174), Expect = 4.488e-19
Identity = 30/59 (50.85%), Postives = 40/59 (67.80%), Query Frame = 2

Query:  341 GFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            GF RGL+P+ I G T     + F++KW   DE D+VPA +ANVKCPQ+VI FYE   ++
Sbjct:  192 GFARGLEPERIIGATDSTGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 250

HSP 2 Score: 42.3578 bits (98), Expect = 4.488e-19
Identity = 18/39 (46.15%), Postives = 26/39 (66.67%), Query Frame = 3

Query:  108 GKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLK 224
            G+  YLLKWK +    N+WEPE++L+C  LI  F ++ K
Sbjct:  122 GRVEYLLKWKGFSEEDNTWEPEDNLDCPDLIAEFLQSQK 160

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Medaka
Match: cbx5 (chromobox 5 [Source:NCBI gene;Acc:101174667])

HSP 1 Score: 67.781 bits (164), Expect = 7.558e-13
Identity = 30/63 (47.62%), Postives = 41/63 (65.08%), Query Frame = 2

Query:  335 AYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 523
            A GF+RGL+P+ I G T     + F++KW   DE D+V A +AN KCPQ+VI FYE   ++ E
Sbjct:  129 ARGFERGLEPEKIIGATDSCGDLMFLMKWKDSDEADLVLAKEANHKCPQIVIAFYEERLTWHE 191

[Close]

BLAST of chromobox protein homolog 1 vs. Ensembl Medaka
Match: cbx3b (chromobox protein homolog 3 [Source:NCBI gene;Acc:101159942])

HSP 1 Score: 53.9138 bits (128), Expect = 3.651e-8
Identity = 19/54 (35.19%), Postives = 36/54 (66.67%), Query Frame = 2

Query:  356 LKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSF 517
            L+P+ I G T +   + F++KW   +++ ++PA +A+ +CPQ+VI FYE   ++
Sbjct:  133 LEPECIIGSTDRKGELMFLVKWKNSEDVALLPAREASTRCPQVVIDFYEQKLTW 186

HSP 2 Score: 50.8322 bits (120), Expect = 3.741e-7
Identity = 23/48 (47.92%), Postives = 32/48 (66.67%), Query Frame = 3

Query:   75 VEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKN 218
            VEKII     NG+  Y LKWK +  + N+WEPE++L+C  LI+ F +N
Sbjct:   24 VEKIIRRRVFNGRVEYFLKWKGFTDAENTWEPEDNLDCPELIEEFLRN 71

[Close]

BLAST of chromobox protein homolog 1 vs. Planmine SMEST
Match: SMESG000055315.1 (SMESG000055315.1)

HSP 1 Score: 231.491 bits (589), Expect = 2.249e-76
Identity = 114/115 (99.13%), Postives = 115/115 (100.00%), Query Frame = 1

Query:  757 MDNKEYVKVSANFSENNQLLDEVWWDPGGCNLENDLDCIYDEVYDNQGMEAEKISYYETFLNVPNVSVNSKKTSLINIKKEILDLHSKLDNLHSLESQYMQQLNKYYNDMENLIQ 1101
            MDNKEY+KVSANFSENNQLLDEVWWDPGGCNLENDLDCIYDEVYDNQGMEAEKISYYETFLNVPNVSVNSKKTSLINIKKEILDLHSKLDNLHSLESQYMQQLNKYYNDMENLIQ
Sbjct:    1 MDNKEYIKVSANFSENNQLLDEVWWDPGGCNLENDLDCIYDEVYDNQGMEAEKISYYETFLNVPNVSVNSKKTSLINIKKEILDLHSKLDNLHSLESQYMQQLNKYYNDMENLIQ 115

[Close]

BLAST of chromobox protein homolog 1 vs. Planmine SMEST
Match: SMESG000054374.1 (SMESG000054374.1)

HSP 1 Score: 231.491 bits (589), Expect = 2.249e-76
Identity = 114/115 (99.13%), Postives = 115/115 (100.00%), Query Frame = 1

Query:  757 MDNKEYVKVSANFSENNQLLDEVWWDPGGCNLENDLDCIYDEVYDNQGMEAEKISYYETFLNVPNVSVNSKKTSLINIKKEILDLHSKLDNLHSLESQYMQQLNKYYNDMENLIQ 1101
            MDNKEY+KVSANFSENNQLLDEVWWDPGGCNLENDLDCIYDEVYDNQGMEAEKISYYETFLNVPNVSVNSKKTSLINIKKEILDLHSKLDNLHSLESQYMQQLNKYYNDMENLIQ
Sbjct:    1 MDNKEYIKVSANFSENNQLLDEVWWDPGGCNLENDLDCIYDEVYDNQGMEAEKISYYETFLNVPNVSVNSKKTSLINIKKEILDLHSKLDNLHSLESQYMQQLNKYYNDMENLIQ 115

[Close]

BLAST of chromobox protein homolog 1 vs. Planmine SMEST
Match: SMESG000055314.1 (SMESG000055314.1)

HSP 1 Score: 153.295 bits (386), Expect = 2.957e-73
Identity = 73/74 (98.65%), Postives = 74/74 (100.00%), Query Frame = 3

Query:   57 MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVPV 278
            MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVP+
Sbjct:    1 MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVPI 74

HSP 2 Score: 141.739 bits (356), Expect = 2.957e-73
Identity = 66/66 (100.00%), Postives = 66/66 (100.00%), Query Frame = 2

Query:  326 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 523
            KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE
Sbjct:   76 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 141

[Close]

BLAST of chromobox protein homolog 1 vs. Planmine SMEST
Match: SMESG000054375.1 (SMESG000054375.1)

HSP 1 Score: 153.295 bits (386), Expect = 2.957e-73
Identity = 73/74 (98.65%), Postives = 74/74 (100.00%), Query Frame = 3

Query:   57 MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVPV 278
            MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVP+
Sbjct:    1 MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVPI 74

HSP 2 Score: 141.739 bits (356), Expect = 2.957e-73
Identity = 66/66 (100.00%), Postives = 66/66 (100.00%), Query Frame = 2

Query:  326 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 523
            KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE
Sbjct:   76 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 141

[Close]

BLAST of chromobox protein homolog 1 vs. Planmine SMEST
Match: SMESG000055314.1 (SMESG000055314.1)

HSP 1 Score: 141.354 bits (355), Expect = 7.507e-55
Identity = 66/66 (100.00%), Postives = 66/66 (100.00%), Query Frame = 2

Query:  326 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 523
            KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE
Sbjct:   55 KDHAYGFDRGLKPQIICGVTKKNDAIYFMIKWDGCDEIDVVPAVQANVKCPQLVIRFYENNFSFEE 120

HSP 2 Score: 92.4337 bits (228), Expect = 7.507e-55
Identity = 43/44 (97.73%), Postives = 44/44 (100.00%), Query Frame = 3

Query:  147 SSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVPV 278
            SSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVP+
Sbjct:   10 SSLNSWEPEEHLNCGALIKNFHKNLKLKEFTQNFQLPMTIKVPI 53

The following BLAST results are available for this feature:

BLAST of chromobox protein homolog 1 vs. Ensembl Human
BLAST of chromobox protein homolog 1 vs. Ensembl Celegans
BLAST of chromobox protein homolog 1 vs. Ensembl Fly
BLAST of chromobox protein homolog 1 vs. Ensembl Zebrafish
BLAST of chromobox protein homolog 1 vs. Ensembl Xenopus
BLAST of chromobox protein homolog 1 vs. Ensembl Mouse
BLAST of chromobox protein homolog 1 vs. UniProt/SwissProt
BLAST of chromobox protein homolog 1 vs. TrEMBL
BLAST of chromobox protein homolog 1 vs. Ensembl Cavefish
BLAST of chromobox protein homolog 1 vs. Ensembl Sea Lamprey
BLAST of chromobox protein homolog 1 vs. Ensembl Yeast
BLAST of chromobox protein homolog 1 vs. Ensembl Nematostella
BLAST of chromobox protein homolog 1 vs. Ensembl Medaka
BLAST of chromobox protein homolog 1 vs. Planmine SMEST

BLAST of chromobox protein homolog 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CBX1	7.364e-20	50.85	chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551]	[more]
CBX1	7.589e-20	50.85	chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551]	[more]
CBX1	7.589e-20	50.85	chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551]	[more]
CBX3	1.564e-19	46.03	chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553]	[more]
CBX3	1.564e-19	46.03	chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553]	[more]

BLAST of chromobox protein homolog 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of chromobox protein homolog 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HP1b	1.104e-20	45.76	gene:FBgn0030082 transcript:FBtr0071284	[more]
HP1b	1.104e-20	45.76	gene:FBgn0030082 transcript:FBtr0309871	[more]
HP1b	1.104e-20	45.76	gene:FBgn0030082 transcript:FBtr0301805	[more]
HP6	4.751e-13	45.90	gene:FBgn0031613 transcript:FBtr0077444	[more]
HP1e	2.336e-10	38.33	gene:FBgn0037675 transcript:FBtr0082016	[more]

BLAST of chromobox protein homolog 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cbx1b	3.942e-20	50.85	chromobox homolog 1b (HP1 beta homolog Drosophila)...	[more]
cbx1b	3.942e-20	50.85	chromobox homolog 1b (HP1 beta homolog Drosophila)...	[more]
cbx3a	6.331e-20	44.44	chromobox homolog 3a (HP1 gamma homolog, Drosophil...	[more]
cbx3a	6.431e-20	44.44	chromobox homolog 3a (HP1 gamma homolog, Drosophil...	[more]
cbx1a	1.173e-19	48.44	chromobox homolog 1a (HP1 beta homolog Drosophila)...	[more]

BLAST of chromobox protein homolog 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
stab2	3.864e-21	49.21	stabilin 2 [Source:Xenbase;Acc:XB-GENE-491156]	[more]
zbtb11	5.184e-20	50.85	zinc finger and BTB domain containing 11 [Source:X...	[more]
tnfaip6	1.597e-18	49.21	TNF alpha induced protein 6 [Source:Xenbase;Acc:XB...	[more]
ENSXETT00000037867.1	4.473e-6	47.17	chromodomain Y like [Source:NCBI gene;Acc:10049195...	[more]
ENSXETT00000025504.1	4.504e-6	47.17	chromodomain Y like [Source:NCBI gene;Acc:10049195...	[more]

BLAST of chromobox protein homolog 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cbx1	5.501e-20	50.85	chromobox 1 [Source:MGI Symbol;Acc:MGI:105369]	[more]
Cbx3	1.133e-19	46.03	chromobox 3 [Source:MGI Symbol;Acc:MGI:108515]	[more]
Cbx3	1.133e-19	46.03	chromobox 3 [Source:MGI Symbol;Acc:MGI:108515]	[more]
Cbx3	1.133e-19	46.03	chromobox 3 [Source:MGI Symbol;Acc:MGI:108515]	[more]
Cbx5	2.129e-19	49.21	chromobox 5 [Source:MGI Symbol;Acc:MGI:109372]	[more]

BLAST of chromobox protein homolog 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P23198\|CBX3_MOUSE	2.647e-19	46.03	Chromobox protein homolog 3 OS=Mus musculus OX=100...	[more]
sp\|P83917\|CBX1_MOUSE	3.302e-19	50.85	Chromobox protein homolog 1 OS=Mus musculus OX=100...	[more]
sp\|P83916\|CBX1_HUMAN	3.302e-19	50.85	Chromobox protein homolog 1 OS=Homo sapiens OX=960...	[more]
sp\|Q5R6X7\|CBX3_PONAB	6.805e-19	46.03	Chromobox protein homolog 3 OS=Pongo abelii OX=960...	[more]
sp\|Q13185\|CBX3_HUMAN	6.805e-19	46.03	Chromobox protein homolog 3 OS=Homo sapiens OX=960...	[more]

BLAST of chromobox protein homolog 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
M9NNX2	5.740e-70	98.65	Heterochromatin protein 1-like protein 2 OS=Schmid...	[more]
A0A504YE48	1.434e-24	64.06	Chromobox protein 1 (Heterochromatin protein 1 bet...	[more]
A0A4E0RD81	1.469e-24	64.06	Chromobox protein 1 (Heterochromatin protein 1 bet...	[more]
J3JTC0	1.863e-24	56.67	Uncharacterized protein OS=Dendroctonus ponderosae...	[more]
A0A224YJX0	3.863e-24	55.00	Chromobox protein 3 OS=Rhipicephalus zambeziensis ...	[more]

BLAST of chromobox protein homolog 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cbx1a	1.284e-19	46.88	chromobox protein homolog 1-like [Source:NCBI gene...	[more]
cbx1a	1.284e-19	46.88	chromobox protein homolog 1-like [Source:NCBI gene...	[more]
cbx5	1.356e-18	47.62	chromobox 5 [Source:NCBI gene;Acc:103047453]	[more]
cbx3a	2.379e-18	42.86	chromobox protein homolog 3-like [Source:NCBI gene...	[more]
cbx3a	3.668e-18	42.86	chromobox protein homolog 3-like [Source:NCBI gene...	[more]

BLAST of chromobox protein homolog 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CBX1	1.045e-21	52.54	chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551]	[more]
CBX1	1.669e-20	49.15	chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551]	[more]
ENSPMAT00000009664.1	5.676e-16	50.85	pep scaffold:Pmarinus_7.0:GL477881:602658:605312:-...	[more]
CBX1	1.826e-15	47.62	chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551]	[more]
CBX1	2.968e-13	49.15	chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551]	[more]

BLAST of chromobox protein homolog 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of chromobox protein homolog 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO48908	1.372e-8	35.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27150	2.970e-6	36.36	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of chromobox protein homolog 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CBX1	5.557e-20	49.21	chromobox protein homolog 1 [Source:NCBI gene;Acc:...	[more]
cbx3a	1.214e-19	42.86	chromobox protein homolog 3 [Source:NCBI gene;Acc:...	[more]
CBX1	4.488e-19	50.85	chromobox 1 [Source:NCBI gene;Acc:101155967]	[more]
cbx5	7.558e-13	47.62	chromobox 5 [Source:NCBI gene;Acc:101174667]	[more]
cbx3b	3.651e-8	35.19	chromobox protein homolog 3 [Source:NCBI gene;Acc:...	[more]

BLAST of chromobox protein homolog 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000055315.1	2.249e-76	99.13	SMESG000055315.1	[more]
SMESG000054374.1	2.249e-76	99.13	SMESG000054374.1	[more]
SMESG000055314.1	2.957e-73	98.65	SMESG000055314.1	[more]
SMESG000054375.1	2.957e-73	98.65	SMESG000054375.1	[more]
SMESG000055314.1	7.507e-55	100.00	SMESG000055314.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30033701 ID=SMED30033701|Name=chromobox protein homolog 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1120bp
CCTTGTCAATAATTTTGAATTAGCTCAGGAAATACTTGTTTTAATCAGTT
TTGTTAATGTCTGAAGTAATTGAGGTTGAAAAAATTATTGCTGTTTCTAA
TCGAAATGGCAAAAGATGTTACTTGTTGAAATGGAAAAATTATGATAGTT
CATTGAATTCGTGGGAGCCCGAAGAACATTTAAATTGTGGTGCATTAATA
AAAAACTTTCATAAAAATTTGAAATTAAAAGAATTTACCCAAAATTTTCA
ATTACCAATGACTATAAAAGTTCCTGTTAGAATTGGTTTCTTATTAAACG
CTACATTTTATTATTATAGATTATTAAAGATCATGCTTACGGATTTGATA
GGGGACTAAAGCCACAAATAATATGTGGCGTTACTAAAAAAAATGATGCA
ATTTATTTTATGATAAAATGGGATGGTTGTGACGAAATAGATGTTGTTCC
AGCTGTTCAAGCTAATGTGAAATGTCCACAGCTTGTAATTAGATTCTATG
AAAATAACTTTAGTTTTGAAGAATAAATAATTGTTGTGTAGTTATTGTGT
CGTGTTATTGATTATTAAAATAAAATTTCATTGGTTAATGGTTATTCAGT
GTATGTTTCTTTTTAACAAGTCATAATTGGAAAATGACTTCCATATTAAA
AAAGAAAAAATGGCGGATTAATTTACCATGTGTCTCTAAATTTAAACCTA
TCAAGTTTAAGAAAATAAATCTTATTGGAAATAAGTTTAAGTTAAATCGC
CATCATATGGATAACAAGGAATATGTAAAAGTAAGTGCTAATTTTTCTGA
AAACAATCAGCTTCTCGACGAAGTGTGGTGGGATCCAGGTGGTTGCAATT
TAGAAAACGATTTGGACTGCATCTATGACGAAGTTTATGATAACCAAGGA
ATGGAAGCAGAGAAAATATCATACTACGAAACCTTCTTGAATGTTCCAAA
TGTTTCAGTTAACAGCAAGAAGACATCTCTAATTAATATTAAAAAAGAAA
TATTGGATTTACATTCGAAATTGGATAATTTACACAGCCTTGAAAGTCAA
TATATGCAGCAGTTGAATAAATATTATAATGATATGGAAAATTTAATTCA
ATAAATTTTTTGGCGTGGTG

protein sequence of SMED30033701-orf-1

>SMED30033701-orf-1 ID=SMED30033701-orf-1|Name=SMED30033701-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=157bp
MTSILKKKKWRINLPCVSKFKPIKFKKINLIGNKFKLNRHHMDNKEYVKV
SANFSENNQLLDEVWWDPGGCNLENDLDCIYDEVYDNQGMEAEKISYYET
FLNVPNVSVNSKKTSLINIKKEILDLHSKLDNLHSLESQYMQQLNKYYND
MENLIQ*

protein sequence of SMED30033701-orf-2

>SMED30033701-orf-2 ID=SMED30033701-orf-2|Name=SMED30033701-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=101bp
MSEVIEVEKIIAVSNRNGKRCYLLKWKNYDSSLNSWEPEEHLNCGALIKN
FHKNLKLKEFTQNFQLPMTIKVPVRIGFLLNATFYYYRLLKIMLTDLIGD
*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005719	nuclear euchromatin
GO:0005634	nucleus

Vocabulary: **biological process**
Term	Definition
GO:0045892	negative regulation of transcription, DNA-templated

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000429	neoblast
PLANA:0000484	secretory system
PLANA:0002032	epidermal cell
PLANA:0002109	X1 cell
PLANA:0002142	parenchyma
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR000953	Chromo/chromo_shadow_dom
IPR023780	Chromo_domain
IPR023779	Chromodomain_CS
IPR016197	Chromo-like_dom_sf
IPR008251	Chromo_shadow_dom

Main menu

chromobox protein homolog 1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 18

Owlery

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