TNF receptor associated factor-2
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30033686 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 89.7373 bits (221), Expect = 3.084e-18 Identity = 123/546 (22.53%), Postives = 236/546 (43.22%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDN--CEFDDELSAIEDHISICNKSKNSCPLFSKGCDRND----LLQDEMNQHLIKDIDF------HIKLIVKII-------DDLPATLKNTAQSKNAD---QSDNTAQSKNTAQSENAAQSE---KKIFSNLREMLHEFQ-EKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSES-QN-VMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C +L P CG RFC SC+ L+ S+ C CQ + I D+ V D+ + +++ C +++ C L + H+ KN C C R D +L+ ++ H+ K + H K V +I D P + + + +S+ T Q ++ +A Q K+ ++L + + Q E +K+ IQ + ++ S ++E K+M NE K L+ I+ ++LK + E + +++ + MKS ES QN V L +V +++ + + +G++E + D++ +H++R + M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 39 YKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKC----TACQ-ESIVKDK-VFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHL------KNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIER-QKEMLRNNESKILH------LQRVIDSQAEKLKELDKEIRPFRQNWEEADS-------------MKSSVESLQNRVTELESV-DKSAGQVARNTGLLESQLSRHDQM-LSVHDIR-----------LADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 537
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 89.7373 bits (221), Expect = 3.084e-18 Identity = 123/546 (22.53%), Postives = 236/546 (43.22%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDN--CEFDDELSAIEDHISICNKSKNSCPLFSKGCDRND----LLQDEMNQHLIKDIDF------HIKLIVKII-------DDLPATLKNTAQSKNAD---QSDNTAQSKNTAQSENAAQSE---KKIFSNLREMLHEFQ-EKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSES-QN-VMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C +L P CG RFC SC+ L+ S+ C CQ + I D+ V D+ + +++ C +++ C L + H+ KN C C R D +L+ ++ H+ K + H K V +I D P + + + +S+ T Q ++ +A Q K+ ++L + + Q E +K+ IQ + ++ S ++E K+M NE K L+ I+ ++LK + E + +++ + MKS ES QN V L +V +++ + + +G++E + D++ +H++R + M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 39 YKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKC----TACQ-ESIVKDK-VFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHL------KNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIER-QKEMLRNNESKILH------LQRVIDSQAEKLKELDKEIRPFRQNWEEADS-------------MKSSVESLQNRVTELESV-DKSAGQVARNTGLLESQLSRHDQM-LSVHDIR-----------LADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 537
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 89.7373 bits (221), Expect = 3.702e-18 Identity = 123/558 (22.04%), Postives = 238/558 (42.65%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDN--CEFDDELSAIEDHISICNKSKNSCPLFSKGCDRND----LLQDEMNQHLIKDIDF------HIKLIVKII-------DDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQS-EKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKS----VTDENEILKNEFQDLKALGVIIKESILDIQMKSGSE-SQNVMNLRTVSEQTYDEQQKLSGIVEKLQ------EKIDKLSQDLHEMRENVDS---------TKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C +L P CG RFC SC+ L+ S+ C CQ + I D+ V D+ + +++ C +++ C L + H+ KN C C R D +L+ ++ H+ K + H K V +I D P + + + + S + ++ NA + K + + + ++ + ++ SS +Q + N LK S+S+ K +S L NE+ +KS I + ++ S + + E+L+N + L + ++D Q + E + + R Q ++E + VE LQ E +DK + + ++S + + ++ M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 39 YKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKC----TACQ-ESIVKDK-VFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHL------KNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHV----NLLKEWSNSLEKKVSLLQ-----NESVEKNKS--IQSLHNQICSFEIEIERQKEMLRNNESKILHL-----QRVIDSQAEKLKELDKEIRPFR----QNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 562
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 89.7373 bits (221), Expect = 3.702e-18 Identity = 123/558 (22.04%), Postives = 238/558 (42.65%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDN--CEFDDELSAIEDHISICNKSKNSCPLFSKGCDRND----LLQDEMNQHLIKDIDF------HIKLIVKII-------DDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQS-EKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKS----VTDENEILKNEFQDLKALGVIIKESILDIQMKSGSE-SQNVMNLRTVSEQTYDEQQKLSGIVEKLQ------EKIDKLSQDLHEMRENVDS---------TKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C +L P CG RFC SC+ L+ S+ C CQ + I D+ V D+ + +++ C +++ C L + H+ KN C C R D +L+ ++ H+ K + H K V +I D P + + + + S + ++ NA + K + + + ++ + ++ SS +Q + N LK S+S+ K +S L NE+ +KS I + ++ S + + E+L+N + L + ++D Q + E + + R Q ++E + VE LQ E +DK + + ++S + + ++ M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 39 YKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKC----TACQ-ESIVKDK-VFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHL------KNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHV----NLLKEWSNSLEKKVSLLQ-----NESVEKNKS--IQSLHNQICSFEIEIERQKEMLRNNESKILHL-----QRVIDSQAEKLKELDKEIRPFR----QNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 562
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 87.8113 bits (216), Expect = 1.043e-17 Identity = 116/522 (22.22%), Postives = 219/522 (41.95%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSK-NADQSDNTAQS-KNTAQSENAAQSEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSES-QN-VMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C +L P CG RFC SC+ L+ S+ C A + S VK K DNC E+ A++ + C S+GC L+ + HL D F ++LP + + D D+ ++ K + + +S+ + + +L E +K+ IQ + ++ S ++E K+M NE K L+ I+ ++LK + E + +++ + MKS ES QN V L +V +++ + + +G++E + D++ +H++R + M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 39 YKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKC-----------------------TACQESIVKDKVFKDNC-CKREILALQIY----------CRNESRGCAEQ-LMLGHLLVHLKNDCHF---------EELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQVSLLQ--NESVEKNKSIQSLHNQICSFEIEIER-QKEMLRNNESKILH------LQRVIDSQAEKLKELDKEIRPFRQNWEEADS-------------MKSSVESLQNRVTELESV-DKSAGQVARNTGLLESQLSRHDQM-LSVHDIR-----------LADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 479
BLAST of TNF receptor associated factor-2 vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 49.6766 bits (117), Expect = 4.320e-6 Identity = 41/147 (27.89%), Postives = 66/147 (44.90%), Query Frame = 1 Query: 1231 WRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKM--CLRLW----KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATE------FASCSLKFSCYRTNEAW-KKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIK 1632 W+ID + NEA + + S F S G KM C L+ A + + L+ G +D +EWP+ + ISL+DQ E + K + NE + +P+ E+N G + F + N +K+DKIY++ Sbjct: 267 WKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKL---KANEKFLARPRGERNAAFGSQ--SFCSLAILQNYVKDDKIYVQ 408
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: traf3 (TNF receptor-associated factor 3 [Source:ZFIN;Acc:ZDB-GENE-040801-257]) HSP 1 Score: 109.768 bits (273), Expect = 7.024e-25 Identity = 121/574 (21.08%), Postives = 238/574 (41.46%), Query Frame = 1 Query: 73 PEDIFMDLWRVIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLD---RDVVSDHPMAVRLSQVKVKCIHD--NCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFH--------IKLIV--------KIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQ------SEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKL----------SQDLHEMRENV---DSTKKEFQIKIMEIEFESGKSEKS---GYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 PE F L ++ H + + C C+ +L P CG RFC SCI + L++ N CP L P+ D RDV + + +KV C + C+ L + +H+ IC + CPL G + +++ +M +HL + +K+ + + P N + +S+ ++ + +++ S K + +RE F ++ + ++ E V+S + YK L PS S + ++ ++ + + ++N L+ + ++ L E +L+++M E + + LR + E E + L G VE ++ + L S L + + + D +++ E++ + E + G W+I ++ + EA+ S + S F++ G KMC R++ + + G F ++ G YD +++WP++ +V + L+DQ A + + K ++ ++++P E N G L +T + N IK+D I+IK V+ Sbjct: 31 PEPGFSPLH---GGFRDHFVTTPEPKYCCETCRLVLCNPRQTECGHRFCESCINELLSKPNPVCPA-----DLLPLFEDKIFRDVCCNR----EIMALKVYCRSEKNGCKEQMCLQQVMEHLVICPYFEVPCPL---GKCKEKMMRKDMPEHLSRKCKHREVTCEFCSLKMALTELQKHKETVCPAFPVACPNHCSFSSILRSELSSHQHDCPKAQVTCSFIRYGCSYKGLNQEMREHESSFASEHLRMMAVRNTTLEAKVEDVKS-------ELMERYKVL-----PSLSSRLAEVERQYEEMREKNRQLEQKLVSMQMLMSSHSEKLLEVEM----ELRELRPLRAMRE----EVETLRGSVESMRSMVSSLDSSCVNSASGSHTLASLEQQLTRHDDLMSVHDVRLAEMDLKLQVLETASFNGTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLQWPFKQKVTLMLMDQGPARKHLGDAFKPD--PSSSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTVDT 567
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: unm_sa808 (un-named sa808 [Source:ZFIN;Acc:ZDB-GENE-120727-21]) HSP 1 Score: 75.8702 bits (185), Expect = 9.719e-15 Identity = 52/194 (26.80%), Postives = 93/194 (47.94%), Query Frame = 1 Query: 1093 QEKIDKLSQDLHEMRENV---DSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 Q+KI+ LS + ++ V D T E + ++ E+ + G F WRI +F+K +AI + S +F++ G KMCLR++ +L F ++ G D +++WP+ +V + L+DQ+N F T+ ++++P SE N G L + I++D I+IK +V+ Sbjct: 91 QDKIEALSNKVRQLERQVGVKDLTVAEMEGRLREMS----ATTFDGVFIWRISDFTKKRQDAIAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGMSDALLKWPFNQKVTLMLLDQSNREHIIDA---FRPDITSSSFQRPVSEMNIASGCPLFCPLAKLEGKNSYIRDDTIFIKAIVD 277
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 73.559 bits (179), Expect = 2.675e-13 Identity = 51/196 (26.02%), Postives = 94/196 (47.96%), Query Frame = 1 Query: 1093 QEKIDKLSQDLHEMRENVDSTKKEFQIK-----IMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 QEKI+ LS + ++ + T ++ Q+ + E++F G F W+I FS+ +A+ + S +F+S G KMCLRL+ +L F ++ G YD +++WP+ +V + L+DQ N F ++ ++++P SE N G L ++ +++D I+IK +V+ Sbjct: 342 QEKIENLSNKVRQLERTL--TTRDLQLAESEQSLRELQF----CTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIID---AFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 528
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 73.559 bits (179), Expect = 2.675e-13 Identity = 51/196 (26.02%), Postives = 94/196 (47.96%), Query Frame = 1 Query: 1093 QEKIDKLSQDLHEMRENVDSTKKEFQIK-----IMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 QEKI+ LS + ++ + T ++ Q+ + E++F G F W+I FS+ +A+ + S +F+S G KMCLRL+ +L F ++ G YD +++WP+ +V + L+DQ N F ++ ++++P SE N G L ++ +++D I+IK +V+ Sbjct: 342 QEKIENLSNKVRQLERTL--TTRDLQLAESEQSLRELQF----CTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIID---AFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 528
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 73.1738 bits (178), Expect = 3.870e-13 Identity = 51/196 (26.02%), Postives = 94/196 (47.96%), Query Frame = 1 Query: 1093 QEKIDKLSQDLHEMRENVDSTKKEFQIK-----IMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 QEKI+ LS + ++ + T ++ Q+ + E++F G F W+I FS+ +A+ + S +F+S G KMCLRL+ +L F ++ G YD +++WP+ +V + L+DQ N F ++ ++++P SE N G L ++ +++D I+IK +V+ Sbjct: 355 QEKIENLSNKVRQLERTL--TTRDLQLAESEQSLRELQF----CTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIID---AFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 541
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 80.4925 bits (197), Expect = 2.365e-15 Identity = 113/551 (20.51%), Postives = 224/551 (40.65%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPN-----------KSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIH--DNCEFDDELSA-------------IEDHIS-ICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLP--ATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVE----SHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + ++ KC C+ +L P CG RFC +C+ L+ ++ C K C+ + + L ++ L + IH +C+F +ELS + DHI C + C K C RN + EM +H +D+D ++ P ++K+ +S+ +Q ++ + Q N + ML E ++K+ IQ + ++ S ++E + + + + + +++ E +IR L+ DE + +K+ ++ L+ + S L++ K+ + N + Q Q LS +H++R + M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ + + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 34 YKERFLKPVEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQF-EELSCPRADCKEKVIRKDLSDHIEKTCKYRETPC----KFC-RNQVPLVEMQKH--EDVD-----CPSVVISCPHMCSVKSLLRSEGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQ--NESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRN-LRQTGDEADGMKSNYESLQN-----RLSQLEVMAKNAAS----WNPGVLETQINRHDQMLS----------------VHDIR-----------LADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 530
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 76.2554 bits (186), Expect = 5.090e-14 Identity = 113/561 (20.14%), Postives = 219/561 (39.04%), Query Frame = 1 Query: 154 KCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPN-----------KSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIH--DNCEFDDELSA-------------IEDHI--------SICNKSKNSCPLF-----------------SKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQS-ENAAQSEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVE----SHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 KC C+ +L P CG RFC +C+ L+ ++ C K C+ + + L ++ L + IH +C+F+ ELS + DHI + C +N PL C LL+ E+N HL++ ++ K T K T Q A ++ + Q N + N +++ + N E ++K+ IQ + ++ S ++E + + + + + +++ E +IR L+ DE + +K+ ++ L+ + S L++ K+ + N + Q Q LS +H++R + M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ + + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 47 KCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFE-ELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYG---CTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQN---------ESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRN-LRQTGDEADGMKSNYESLQN-----RLSQLEVMAKNAAS----WNPGVLETQINRHDQMLS----------------VHDIR-----------LADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 555
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: egf (epidermal growth factor [Source:Xenbase;Acc:XB-GENE-951823]) HSP 1 Score: 67.3958 bits (163), Expect = 3.960e-11 Identity = 68/300 (22.67%), Postives = 126/300 (42.00%), Query Frame = 1 Query: 847 FGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALG--VIIKESILDIQMKSGSESQNVM-NLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDL----HEMRENVDSTKK------EFQIKIMEIEFESGKSEK---SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW-------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNT-GLGDKLIKFETFVHNTNL-----IKNDKIYIKCMVNNFKDI 1659 FG ++ ND+ + L+ T + ++ Q L++ V + DI S+ + ++ TV Q + L+E I++L L H++RE + + E + I ++ G+ E SG F WRI+NF+ + + ++S F++ G K+CLRL + Y+ + G YD+++ WP Q + +S++DQ+ A+++P +N G G + TF+H L +KND + ++C V D+ Sbjct: 249 FGCTEKMQRNDLARHLQEFTQAH--MRMMAQTLRSFSSSVTPTSHMPDISFCDPSQFEPAPPSVATVHSSHTPSQNDCTQETRNLRETIEQLEGRLVRQDHQIRELIAKMETQCTYVNELKHTIRSLDNRLGEMESQQCSGIFIWRINNFNSLLKNQEEERPVVIHSQGFYTGKPGYKLCLRLHLQLPSAQRCANYISLFVHTMQGEYDSLLPWPLQGTIRLSILDQSEGVAMQDQEEVMDTKPELLAFQRPTVARNPKGFG-----YVTFMHLQALKQRQYVKNDTLLVRCSVTTHLDL 541
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 66.2402 bits (160), Expect = 6.618e-11 Identity = 51/209 (24.40%), Postives = 98/209 (46.89%), Query Frame = 1 Query: 1042 EQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEF-ESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTN-LIKNDKIYIKCMVN 1644 E++ ++L+ + QEK++ L+ + ++ + +KE + +E ES S G F W+I F K +AI + S F++ G KMCLR++ +L F ++ G D ++ WP+ +V + L+DQ N F ++ ++++P SE N G L + + N +++D I++K +V+ Sbjct: 274 ERSSHAAEELARQLRAAQEKVEALTTKVRQLERTLG--QKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNREHVID---AFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIVD 477
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 63.1586 bits (152), Expect = 5.944e-10 Identity = 49/198 (24.75%), Postives = 93/198 (46.97%), Query Frame = 1 Query: 1081 VEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKS---GYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTN-LIKNDKIYIKCMVN 1644 VE+ ++L++ L ++ T + ++ + E+E +SE S G F W+I F K +AI + S F++ G KMCLR++ +L F ++ G D ++ WP+ +V + L+DQ N F ++ ++++P SE N G L + + N +++D I++K +V+ Sbjct: 256 VERSSHAAEELARQLRAADTRLERTLGQKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNREHVID---AFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIVD 450
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 92.4337 bits (228), Expect = 2.946e-19 Identity = 123/544 (22.61%), Postives = 238/544 (43.75%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRND----LLQDEMNQHLIKDIDF------HIKLIVKII-------DDLPATLKNTAQSKNAD---QSDNTAQSKNTAQSENAAQSE---KKIFSNLREMLHEFQ-EKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSES-QN-VMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C+ +L P CG RFC SC+ L+ S+ C CQ + I D+ V D+ + ++V C ++ ++L+ H+ + KN C C R D +L+ ++ H+ K + H K V +I D P + + + +S+ T Q ++ +A Q K+ ++L + + Q E +K+ IQ + ++ S ++E K+M NE K L+ I+ ++LK + E + +++ + MKS ES QN V L +V +++ + + +G++E + D++ +H++R + M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 38 YKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKC----TACQ-ESIIKDK-VFKDNCCKREILALQVYCRNEGRGCAEQLTL--GHLLV--HLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIER-QKEMLRNNESKILH------LQRVIDSQAEKLKELDKEIRPFRQNWEEADS-------------MKSSVESLQNRVTELESV-DKSAGQAARNTGLLESQLSRHDQM-LSVHDIR-----------LADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 536
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 92.4337 bits (228), Expect = 2.946e-19 Identity = 123/544 (22.61%), Postives = 238/544 (43.75%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRND----LLQDEMNQHLIKDIDF------HIKLIVKII-------DDLPATLKNTAQSKNAD---QSDNTAQSKNTAQSENAAQSE---KKIFSNLREMLHEFQ-EKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSES-QN-VMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C+ +L P CG RFC SC+ L+ S+ C CQ + I D+ V D+ + ++V C ++ ++L+ H+ + KN C C R D +L+ ++ H+ K + H K V +I D P + + + +S+ T Q ++ +A Q K+ ++L + + Q E +K+ IQ + ++ S ++E K+M NE K L+ I+ ++LK + E + +++ + MKS ES QN V L +V +++ + + +G++E + D++ +H++R + M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 38 YKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKC----TACQ-ESIIKDK-VFKDNCCKREILALQVYCRNEGRGCAEQLTL--GHLLV--HLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIER-QKEMLRNNESKILH------LQRVIDSQAEKLKELDKEIRPFRQNWEEADS-------------MKSSVESLQNRVTELESV-DKSAGQAARNTGLLESQLSRHDQM-LSVHDIR-----------LADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 536
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 90.8929 bits (224), Expect = 9.014e-19 Identity = 121/556 (21.76%), Postives = 237/556 (42.63%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRND----LLQDEMNQHLIKDIDF------HIKLIVKII-------DDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQS-EKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKS----VTDENEILKNEFQDLKALGVIIKESILDIQMKSGSE-SQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTK---------------KEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C+ +L P CG RFC SC+ L+ S+ C CQ + I D+ V D+ + ++V C ++ ++L+ H+ + KN C C R D +L+ ++ H+ K + H K V +I D P + + + + S + ++ NA + K + + + ++ + ++ SS +Q + N LK S+S+ K +S L NE+ +KS I + ++ S + + E+L+N + L + ++D Q + E + + R Q ++E + VE LQ ++ +L + +T + ++ M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 38 YKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKC----TACQ-ESIIKDK-VFKDNCCKREILALQVYCRNEGRGCAEQLTL--GHLLV--HLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHV----NLLKEWSNSLEKKVSLLQ-----NESVEKNKS--IQSLHNQICSFEIEIERQKEMLRNNESKILHL-----QRVIDSQAEKLKELDKEIRPFR----QNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 561
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 72.7886 bits (177), Expect = 5.174e-13 Identity = 52/214 (24.30%), Postives = 101/214 (47.20%), Query Frame = 1 Query: 1033 TVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENV---DSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTN-LIKNDKIYIKCMVN 1644 V+ + Q +L Q+KI+ LS + ++ ++ D + + K+ E+E S G F W+I +F++ EA+ + S +F++ G KMCLR++ +L F ++ GP D +++WP+ +V + L+D N F T+ ++++P S+ N G L + + N +++D I+IK +V+ Sbjct: 304 AVTAEACSRQHRLD------QDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEV----STYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVID---AFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 504
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 72.4034 bits (176), Expect = 6.112e-13 Identity = 49/194 (25.26%), Postives = 95/194 (48.97%), Query Frame = 1 Query: 1093 QEKIDKLSQDLHEMRENV---DSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTN-LIKNDKIYIKCMVN 1644 Q+KI+ LS + ++ ++ D + + K+ E+E S G F W+I +F++ EA+ + S +F++ G KMCLR++ +L F ++ GP D +++WP+ +V + L+D N F T+ ++++P S+ N G L + + N +++D I+IK +V+ Sbjct: 311 QDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEV----STYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVID---AFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2) HSP 1 Score: 90.8929 bits (224), Expect = 6.305e-18 Identity = 121/556 (21.76%), Postives = 237/556 (42.63%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRND----LLQDEMNQHLIKDIDF------HIKLIVKII-------DDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQS-EKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKS----VTDENEILKNEFQDLKALGVIIKESILDIQMKSGSE-SQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTK---------------KEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C+ +L P CG RFC SC+ L+ S+ C CQ + I D+ V D+ + ++V C ++ ++L+ H+ + KN C C R D +L+ ++ H+ K + H K V +I D P + + + + S + ++ NA + K + + + ++ + ++ SS +Q + N LK S+S+ K +S L NE+ +KS I + ++ S + + E+L+N + L + ++D Q + E + + R Q ++E + VE LQ ++ +L + +T + ++ M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 38 YKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKC----TACQ-ESIIKDK-VFKDNCCKREILALQVYCRNEGRGCAEQLTL--GHLLV--HLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHV----NLLKEWSNSLEKKVSLLQ-----NESVEKNKS--IQSLHNQICSFEIEIERQKEMLRNNESKILHL-----QRVIDSQAEKLKELDKEIRPFR----QNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 561
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2) HSP 1 Score: 89.7373 bits (221), Expect = 1.778e-17 Identity = 123/558 (22.04%), Postives = 238/558 (42.65%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDN--CEFDDELSAIEDHISICNKSKNSCPLFSKGCDRND----LLQDEMNQHLIKDIDF------HIKLIVKII-------DDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQS-EKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKS----VTDENEILKNEFQDLKALGVIIKESILDIQMKSGSE-SQNVMNLRTVSEQTYDEQQKLSGIVEKLQ------EKIDKLSQDLHEMRENVDS---------TKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 YK + + D+ KC C +L P CG RFC SC+ L+ S+ C CQ + I D+ V D+ + +++ C +++ C L + H+ KN C C R D +L+ ++ H+ K + H K V +I D P + + + + S + ++ NA + K + + + ++ + ++ SS +Q + N LK S+S+ K +S L NE+ +KS I + ++ S + + E+L+N + L + ++D Q + E + + R Q ++E + VE LQ E +DK + + ++S + + ++ M++ F+ ++ +G W+I ++ + EA+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ ++ + K + ++KKP E N G + +T + N IK+D I+IK +V+ Sbjct: 39 YKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKC----TACQ-ESIVKDK-VFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHL------KNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHV----NLLKEWSNSLEKKVSLLQ-----NESVEKNKS--IQSLHNQICSFEIEIERQKEMLRNNESKILHL-----QRVIDSQAEKLKELDKEIRPFR----QNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPD--PNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 562
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|O00463|TRAF5_HUMAN (TNF receptor-associated factor 5 OS=Homo sapiens OX=9606 GN=TRAF5 PE=1 SV=2) HSP 1 Score: 75.0998 bits (183), Expect = 6.823e-13 Identity = 119/560 (21.25%), Postives = 223/560 (39.82%), Query Frame = 1 Query: 118 KYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTY--CPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIH-DNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDF------HIKLIVKIID----------DLPATLKNT--------------AQSKNADQSDNTAQSKNTAQSENAAQSEKKIFSNLREMLHEFQEKNDK-SSVIQEIQRELNSLKVESHSIMKDMSAL-NEYKKLNETFGPSKS--PAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGI------VEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTN--LIKNDKIYIKCMVN 1644 +Y ++ + + KC C +L P CG RFC CI L E NT CP K + ++V D+ + + V C + C L +DH+ C C ++ C R +L+ ++ +HL F + K V +I+ + P N A A+Q D + A ++ ++ S LRE + EKN + I ++ + L + + + + + L E+K+ + FG + S P I Q S D++ L+ + L +QM + + QN +LR + E +QK++ + + L+E+ +K D H +K E + K++E +GK W++ ++ EA+ + + S SF++ G ++C R + +L F ++ G +D++++WP++ V + L+DQ+ F + ++K+P E N G + + N IK+D +++K V+ Sbjct: 32 EYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILS-LRELNTVPICPVD------KEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCS--NEKC-REPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQ-DCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNI----QVFASHIDKSAWLEAQVHQL-------------LQMVN--QQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNK--HDTHINIHKAQLSKNEERFKLLEGTCYNGK------LIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIME---TFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVD 550
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1) HSP 1 Score: 72.4034 bits (176), Expect = 4.275e-12 Identity = 49/194 (25.26%), Postives = 95/194 (48.97%), Query Frame = 1 Query: 1093 QEKIDKLSQDLHEMRENV---DSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTN-LIKNDKIYIKCMVN 1644 Q+KI+ LS + ++ ++ D + + K+ E+E S G F W+I +F++ EA+ + S +F++ G KMCLR++ +L F ++ GP D +++WP+ +V + L+D N F T+ ++++P S+ N G L + + N +++D I+IK +V+ Sbjct: 311 QDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEV----STYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVID---AFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Match: sp|Q12933|TRAF2_HUMAN (TNF receptor-associated factor 2 OS=Homo sapiens OX=9606 GN=TRAF2 PE=1 SV=2) HSP 1 Score: 72.0182 bits (175), Expect = 6.236e-12 Identity = 49/194 (25.26%), Postives = 96/194 (49.48%), Query Frame = 1 Query: 1093 QEKIDKLSQDLHEMRENV---DSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTN-LIKNDKIYIKCMVN 1644 Q+KI+ LS + ++ ++ D + + K++E+E S G F W+I +F++ EA+ + S +F++ G KMCLR++ +L F ++ GP D ++ WP+ +V + L+DQ N F T+ ++++P ++ N G L + + N +++D I+IK +V+ Sbjct: 311 QDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEME----ASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVID---AFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: T1E101 (TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 144.436 bits (363), Expect = 1.034e-33 Identity = 123/527 (23.34%), Postives = 241/527 (45.73%), Query Frame = 1 Query: 103 VIQKYKYHLID-NISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSEKKIFSNLREMLHEFQEKNDKSSV----IQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEI-----LKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTN-EAWKKPKSEKN-TGLG-DKLIKFETFVHNTNLIKNDKIYIKCMVN 1644 ++ KY +D ++++++ C LC ++ C CGC +C++CI YL++++ YCP C+ ++L+ DV + ++ R+S++ VKC + C + EL +++H+ C CP + GC+ LL+DEM +HL + H +LI+ ++L + + + ++ D S K + + A EK + + ++ E + K++ V IQE++ E+ +L S +K + + I RQ ++ + ++ E+ +KN+ +DL K+ I I+M S ++ + ++K++ ++ L+++ NVD F WRI+ +SK + V SDSF QS K CL L+ + L ++ G D+ +EWP + V +S+I+Q + + ++ Y+ N +A+ +PK E+N +G D L+++ ++ ND I + C+V+ Sbjct: 12 LLSKYNVKRVDESVNNDLLCILCNKLMRDACESACGCHYCYTCIRIYLSQNHNYCPGDKTECKEDYLNLEGDVFRNIRLSTRISRIVVKCPNIRCNYTSELLRLKEHLDKCTPESVECPCVTIGCEEEPLLKDEMAKHLTDQVLRHTQLIMSFCNELKSEINHNNETTKEDIS----HLKEVLRVQKALNDEKT--AQMEFLIEELRNKDNMILVLSQDIQEVKNEMITLLTSKESELKKLKS-----------------DIQIFRQEIEFMKNDLEVVGSTDIKNQVKDL-------KKEIFGIKMNIDSNNE-------------ERERKMNNLIR------------LNKLCPNVDMD-----------------------FMWRIEEYSKK-----RRTVTDVYSDSF--QSHNYKFCLNLYIYGDNLGLWCVIMKGEKDDFLEWPMRRTVTLSIIEQDSLKTHKTTVFQYDTYQRNKKAFDRPKDERNDYCIGTDSLVRYSYIKETPMILVNDSIIVACVVH 453
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: I1ZID8 (TNF receptor associated factor-2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 111.694 bits (278), Expect = 2.172e-24 Identity = 56/187 (29.95%), Postives = 102/187 (54.55%), Query Frame = 1 Query: 100 RVIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSEN 660 R++ Y + + + D +KC LCK +LV C RCGCRFC CI +Y++ N YCP + C+ + + + ++ +D+ + ++++++VKC + C+ EL IE+H+ +C +CP F GC++ ++ ++ HL H KLI+ II ++ +K + ++ KN QS+N Sbjct: 8 RLLITYNFEVEGGVPDNLKCDLCKNLLVNACQSRCGCRFCSKCIMEYVSRGNLYCPGGTSECKEENLTICSNIHTDYRVNRKIAKMRVKCPEETCKVYCELVDIEEHLRLCTMKSQNCPFFVLGCNQPKMVIQDLTNHLQNGTFQHSKLIIDIISNMRNDFFGLT-TKEVELREDINLIKNHFQSQN 193
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: F2YA57 (TNF receptor-associated factor OS=Cyprinus carpio OX=7962 GN=TRAF3 PE=2 SV=1) HSP 1 Score: 115.931 bits (289), Expect = 1.751e-23 Identity = 128/574 (22.30%), Postives = 239/574 (41.64%), Query Frame = 1 Query: 73 PEDIFMDLWRVIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLD---RDVVSDHPMAVRLSQVKVKCIHD--NCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSEKKIFSNLREMLHEFQEKNDKSSVI--------------QEIQRELNSLKVESHSIMKDMSALNEYK------KLNETFG--PSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQ-------------DLHEMRENVDSTKKEFQIKIMEIEFESGKSEKS---GYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 PE F+ L ++ H + + +C C+++L P CG RFC SCIT L++ N CP L+P+ D RDV + + +KV C + C+ L + DH+ +C + CPL G + +++ +M++HL + H ++ + + A ++ D + A + + S S LR L Q K+ V QE++ +S E +M + E K +L E + PS S + ++ + + + ++N L+ + ++ L E +L+++M E + + LR + E E + L G VE ++ + L L + D I++ E++ + E + G W+I ++ + EA+ S + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ A + + K + ++++P +E N G L +T + N IK+D I+IK V+ Sbjct: 31 PEPSFLPLH---GGFRDHFVTMPEAKYRCESCRHVLCKPRQTECGHRFCESCITDLLSKPNPVCPA-----DLEPLFEDKIFRDVCCNR----EIMALKVYCRSEKNGCKEQMSLQQVMDHLEVCPYFEVPCPL---GKCKEKMMRKDMSEHLSRKCK-HREITCEFCNH------KMALTELQKHKDTVCPAFPVACPNHCSFS-----SILRSELSSHQHDCPKAQVTCSFIRYGCSFKGLNQEMREHESSFASEHLRLMAVRNTTLEAKVEDVKSELMERYKVLPSLSSRLAEVETQYEEMREKNRQLEQKLVSMQKLMSSHSEKLLEVEM----ELRELRPLRAMRE----EVEALRGSVENMRSIVSSLDSGRVGSSSGSHTLGSLEQQLSRHDDMMSVHDIRLAEMDLKLQVLETASFNGTLIWKIRDYKRRKQEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPD--PNSSSFRRPTAEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTVDT 567
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: A0A2S0NLP0 (TNF receptor-associated factor OS=Ctenopharyngodon idella OX=7959 GN=TRAF3 PE=2 SV=1) HSP 1 Score: 114.39 bits (285), Expect = 5.699e-23 Identity = 117/547 (21.39%), Postives = 229/547 (41.86%), Query Frame = 1 Query: 157 CGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLD---RDVVSDHPMAVRLSQVKVKCIHD--NCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVK-----------------IIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQ------SEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKL----------SQDLHEMRENV---DSTKKEFQIKIMEIEFESGKSEKS---GYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 C C+ +L +P CG RFC SCIT L++ N CP L+P+ D RDV + + +KV C + C+ L + DH+ +C + CPL G + +++ +M +HL + H ++ + + P N + +S+ ++ + +++ + K + +RE F ++ + ++ E V+S + YK L PS S + ++ + + + ++N L+ + ++ L E +L+++M E + + LR + E E + L G VE ++ + L S L + + + D I++ E++ + E + G W+I ++ + EA+ S + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ A + + K + + ++++P E N G L +T + N IK+D I+IK V+ Sbjct: 56 CEACRLVLCIPRQTECGHRFCESCITDLLSKPNPVCPA-----DLEPLFEDKIFRDVCCNR----EIMALKVYCRSEKNGCKEQMSLQRVMDHLEVCPYFEVPCPL---GKCKEKMMRKDMPEHLSRKCK-HREITCEFCNHKMALTELQKHKETVCPAFPVACPNHCSFSSILRSELSSHQHDCPKAQVTCSFIRFGCTYKGLNQEMREHETSFASEHLRMMAVRNTTLEAKVEDVKS-------ELMERYKVL-----PSLSSRLAEVETQYEEMREKNRQLEQKLVSMQMLMSAHSEKLLEVEM----ELRELRPLRAIRE----EVEALRGSVESMRSVVSSLDAGRVGSGSGSHTLGTLEQQLSRHDDMMSVHDIRLAEMDLKLQVLETASFNGTLIWKIRDYKRRKQEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPH--SSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTVDT 567
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Match: A0A2I6ZHU7 (TNF receptor-associated factor OS=Mylopharyngodon piceus OX=75356 PE=2 SV=1) HSP 1 Score: 112.079 bits (279), Expect = 3.611e-22 Identity = 114/543 (20.99%), Postives = 230/543 (42.36%), Query Frame = 1 Query: 157 CGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLD---RDVVSDHPMAVRLSQVKVKCIHD--NCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVK-----------------IIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSEKK--IFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQ-------------DLHEMRENVDSTKKEFQIKIMEIEFESGKSEKS---GYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 C C+ +L +P CG RFC SCIT L++ N CP L+P+ D RDV + + +KV C + C+ L + DH+ +C + CPL G + +++ +M +HL + H ++ + + P N + +S+ ++ + +++ + ++ L + + E E + S ++ + +L+ + + ++ + YK L PS S + ++ + + + ++N L+ + ++ L E +L+++M E + + LR + E E + L G VE ++ + L L + D I++ E++ + E + G W+I ++ + EA+ S + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ A + + K + + ++++P E N G L +T + N IK+D I+IK V+ Sbjct: 56 CEACRLVLCIPRQTECGHRFCESCITYLLSKPNPVCPA-----DLEPLFEDKIFRDVCCNR----EIMALKVYCRSEKNGCKEQMSLQRVMDHLEVCPYFEVPCPL---GKCKEKMMRKDMPEHLSRKCK-HREITCEFCNHKMALTELQKHKETVCPAFPVACPNQCSFSSILRSELSSHQHDCPKAQVTCSFIRFGCTYTGLNQEMRE-HETSFASEHLRMMAVRNTTLEAKVEDVKSEL--MERYKVL-----PSLSSRLAEVETQYEEMREKNRQLEQKLVSMQMLMSAHSEKLLEVEM----ELRELRPLRAIRE----EVEALRGSVESMRSVVSSLDSGRVGSGSGSHTLGTLEQQLSRHDDMMSVHDIRLAEMDLKLQVLETASFNGTLIWKIRDYKRRKQEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPH--SSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTVDT 567
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261]) HSP 1 Score: 83.5741 bits (205), Expect = 1.453e-16 Identity = 122/541 (22.55%), Postives = 229/541 (42.33%), Query Frame = 1 Query: 136 NISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPI-DLDRDVVS------DHPMAVRLSQVKVKCIHDNCEFDDELSAIE-DHISICNKSKNSCPLFSKGCDRNDLLQDEMNQH-------------------LIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQ-SE---KKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 ++ + +C CK +L P +CG RFC C K L S P + C+ + I +++ ++S D+ + + KC +D C ++ L E H C + C + C LL D+ ++H KDI H ++ K P K+ + K + SK+ A+S++A Q SE + + N ++ HE +SS+I+ ++ L L ++ E+++ + G + P + + + Q + AL I+ +L+ +++ + V+ L ++ Q +Q+K +E L K+ +L + L MR D E + + E++F G F W+I +FS+ +A+ + S +F+S G KMCLRL+ +L F ++ G YD +++WP+ +V + L+DQ N F ++ ++++P SE N G L ++ +++D I+IK +V+ Sbjct: 35 SMEPKYQCQQCKGVLRKPFQAQCGHRFCVFCF-KQLTSSG---PIPCEACRAEGIFEMEHSMLSITEAFPDNAARREIDGLPAKCPNDGCSWNGTLKEYEVQHEGRCEFERVKC----EACQMMILLSDK-DRHNERECEARTLNCKYCKVTFSFKDIKAHDEICQK----FPMQCKDCGK-KKIPREKFAEHSKSCAKSKSACQFSEIGCRAVVDNGKQHEHE------QSSIIEHLRLMLAVLS----TVRVRSDGPGEWQE-DSGLGLYRGPEDAAPPGAHAAAHNAAGGPGVQ-QKMTALENIV--CVLNREVE-----RTVLRLEALTRQQQLDQEK----IENLSNKVRQLERTL-TMR---DLQLAESEQALRELQF----CTYDGVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQNNREHIID---AFRPDISSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 527
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252]) HSP 1 Score: 77.7962 bits (190), Expect = 1.011e-14 Identity = 122/555 (21.98%), Postives = 227/555 (40.90%), Query Frame = 1 Query: 157 CGLCKYILVVPCSIRCGCRFCHSCITKYL-NESNTYCPNKSKFCQLKP---------IDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDL-PATLKNTAQSKNADQSDNTAQ-SKNTAQSENAAQSEKKIFSNL-----------RE--------MLHEFQE--KNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLN---------ETFGPSKSPAIND------IRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKS-EKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI----KFETFVHNTNLIKNDKIYIKCMVN 1644 C C +L +CG R+C +C+ L N + C C+ P + LD SD+ + + +++V C++ C + L EDH S C + C + GC +L+ + HL K + L PA L+ + S ++ + A+ K ++ E+ + E +FS + RE LH E +N + SV +R + ++ H +DM+ L + LN +T K+ +++D + Q+L ++ +I++N + AL ++++ L + + ++ N MNL Q L +V + Q+++ +K+ QI ++ + + G F WRI + S+ EA S +F++ G K+C+RL+ + + G F ++ G YD ++ WP++ +V LIDQ F + ++++P SE N G L K + H +K+D ++IKC+V+ Sbjct: 29 CSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTK----CKEDPGSESDSSMMLTLDH-FFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPCNI---GCGLM-VLRKTLATHLEKGCPNNKTTCQVCCSALTPAELQKHSCSNGTEKDLSKAEKRKKDSKQESPKRKETCVFSEIGCTFKGNPDKVREHEVSSTSAHLHLLVEVVRNVQMSVPPPPERTVQYPALDLHLQNQDMTPLPDI-TLNGGELETDSGDTGANDKALSLHDDQAELEVGQQLHALQQRLQIMEN---IITALNREVEKTQLTVVVLE-RDNHNNMNLI----------QHLEAVVAEQQQRL----------------IRKDLQISSLQQSISAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHVVD---AFRPDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKH--AYVKDDTLFIKCVVD 538
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: ENSAMXT00000035169.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:3354744:3362219:1 gene:ENSAMXG00000029095.1 transcript:ENSAMXT00000035169.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 66.2402 bits (160), Expect = 1.751e-12 Identity = 40/149 (26.85%), Postives = 73/149 (48.99%), Query Frame = 1 Query: 1219 GYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 G W+I ++ + EA+ S + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ A + + K + ++++P E N G L +T + N IK+D I+IK V+ Sbjct: 4 GTLIWKIRDYKRRKAEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPD--PNSSSFRRPTGEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTVDT 150
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 70.8626 bits (172), Expect = 1.795e-12 Identity = 88/418 (21.05%), Postives = 168/418 (40.19%), Query Frame = 1 Query: 415 DHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEF-ESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 DHI +C K + C GCD + + +++++ H H+ L++ I + L+ + Q ++ + KI L + L E + K + S +Q + L +F P + + +L S + L Q+L+ L V E+I+ + + S M + Y+ Q +L Q+KI+ L+ + ++ V ++ I ME + E + G F W+I +FSK +A+ + S +F++ G KMCLR++ +L F ++ G D +++WP+ +V + L+DQ N F ++ ++++P S+ N G L + I++D I+IK +V+ Sbjct: 204 DHIKLCTKFRTPCRFHVVGCDMS-VEKEKIHDHERACSYEHLNLLLHFIMGIKVNLE-------------------SLQPQSLELASHKI-QELHQSLRELELKMGQLSAGAPVQGACAPPPPPPPT-------------LATSFTPLPTTVGAALELQLHSEKTKVAELSRRCQELE-LKVGTFENIVCVLNREMERSATTM-------EAYNRQHRLD------QDKIEILNNKVRQLERTVGL--RDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIID---AFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVD 568
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 66.6254 bits (161), Expect = 3.230e-11 Identity = 52/216 (24.07%), Postives = 99/216 (45.83%), Query Frame = 1 Query: 1021 MNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEF-ESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 M + + Y+ Q +L Q+KI+ L+ + ++ V ++ I ME + E + G F W+I +FSK +A+ + S +F++ G KMCLR++ +L F ++ G D +++WP+ +V + L+DQ N F ++ ++++P S+ N G L + I++D I+IK +V+ Sbjct: 251 MERSATTMEAYNRQHRLD------QDKIEILNNKVRQLERTVGL--RDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIID---AFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVD 455
BLAST of TNF receptor associated factor-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 64.6994 bits (156), Expect = 2.080e-11 Identity = 38/167 (22.75%), Postives = 80/167 (47.90%), Query Frame = 1 Query: 1162 EFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVN 1644 E +++++E SGK W+I ++++ EA + S F++ G KMC R + + + G F ++ G YD ++EWP++ V +SL+DQ A S F+ + ++++P + N G L + ++ + +D ++++ +V+ Sbjct: 255 ERRLQVLETAGYSGK------LVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHL--SDTFTPDPASGSFRRPDGDMNVASGCPLFVSHVALEGSSYLVDDTVFVRVVVD 413
BLAST of TNF receptor associated factor-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 63.5438 bits (153), Expect = 5.338e-11 Identity = 34/149 (22.82%), Postives = 73/149 (48.99%), Query Frame = 1 Query: 1219 GYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 G W+I ++++ +A+ + S F++ G +MC R + + + G F ++ G YD ++ WP++ V ++L+DQ A S + K + ++++P S+ N G L + + + +++D I+IK +V+ Sbjct: 325 GKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPD--PASSSFRRPTSDMNIASGCPLFVSHVALESASYLQDDTIFIKVVVDT 471
BLAST of TNF receptor associated factor-2 vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 60.077 bits (144), Expect = 9.871e-10 Identity = 58/264 (21.97%), Postives = 106/264 (40.15%), Query Frame = 1 Query: 982 DIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRE------NVDSTKKEFQIKIMEIEFESGKSEK---SGYFYWRIDNFSKVWNEAIKSN----------NGKVNSDSFFSQSKGCKMCLRL-----------WKAEEYLCAG--------FCLIPGPYDNVIEWPYQMEVFISLIDQ-----TNATEFASCSLKFSCYRTNEAWKKPKSEKNT-GLGDKLIKFETFVHNTNLIKNDKIYIKCMV 1641 D+Q S SQ + + E +L I L+E++ LH++RE N E + +E +SE +G F WR++ FS++ + S ++S F++ G ++CLRL + L AG L+ G YD+ + WP++ + IS++DQ + TE + S A+++P +N G G +H+ + +++D + ++C V Sbjct: 310 DVQTAGASRSQGSRD--RAACDCAQELDRLREITRTLEERV---VLQLHQIRELSAKTDNQQGLLAEATRLVRSLEARVAESESRLCAGIFTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCERDSVHVTEMMDADPQLS------AFQRPSVHRNPKGFGYMNFMDINTLHHRSYLRDDCLVVRCEV 562
BLAST of TNF receptor associated factor-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008091.1 (pep scaffold:Pmarinus_7.0:GL477915:34322:50582:-1 gene:ENSPMAG00000007312.1 transcript:ENSPMAT00000008091.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 54.6842 bits (130), Expect = 2.884e-8 Identity = 27/77 (35.06%), Postives = 45/77 (58.44%), Query Frame = 1 Query: 1219 GYFYWRIDNFSKVWNEAIKSNNG-----KVNSDSFFSQSKGCKMCLRLWKAEEYLCAGFCLIPGPYDNVIEWPYQME 1434 G F W+I + V N ++ NG +++S +FF+ G ++ LRL ++ E++ A L PGPYD + WPYQ++ Sbjct: 325 GMFLWKIKH---VINRLREAGNGAERPPQIDSPAFFTTRYGYRLRLRLCRSGEHVSAYAMLGPGPYDATLAWPYQLK 398
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27]) HSP 1 Score: 96.6709 bits (239), Expect = 3.633e-21 Identity = 122/554 (22.02%), Postives = 215/554 (38.81%), Query Frame = 1 Query: 130 IDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLP-ATLKNTAQSKNA--DQSDNTAQSKNTAQSENAAQSEK--KIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMN---------LRTVSEQTYDE-----------------QQKLSGIVEKL------QEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWK------AEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFA------SCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVN 1644 ID + D C C+ L P +CG RFC CI L CP + Q + DR + + M +C D C++ ++ I H +C K SC S GC +L+ ++ +H+ K+ F + V +D+P TL + A + N K + + +A + + ++ R F V + RE + V H I+ L T G P + ++ +L+ EN K E + K +KE D + G + V N +R E E ++ L ++++L Q +KL++ L ++ ++ K + + + I+ + S G F W+ID F++ + EA N + S F++ G K+C RL+ + YL L+ G YD+++ WP+Q + I+LIDQ N + CS+ F ++P N G +T + + + +++K +V+ Sbjct: 3 IDVLEDRYICNACRMPLNHPMQAQCGHRFCKHCIDVILISPFPACPRDGQTIQALSVFHDRCALVE--MQALPCYCHGRC--DGCQWTGPVAMITVHEEVCAFIKVSCIHASDGCG-EIMLRFQLAKHVEKECPFRLITCVYCQNDVPERTLIEHLKKCPAFPIECPNECGVKRIERKKLSAHTRECPNALTDCR-----FSPLGCTYKVKKIALREHQNKHVIKHMIL-----------LGRTTG-EPQPNLLELENQLERFDGENTSFKTELERHKYEFAQMKERFNDQNARLGIVEKTVANQKGDIAEIWMRFDQENLVGEVRMRDKLKKFKVKTKANKECLLSLMKRLEVQDDSQTNPNKLNRRLSQLESSITIHKTKLFQEDLRIQIQQAIS-YDGTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQDNGMNISETFDPDPCSISF---------QRPTRNINVASGCPRFCSQTVLRTRGYMNENCVFVKVVVD 524
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36]) HSP 1 Score: 66.2402 bits (160), Expect = 1.679e-11 Identity = 35/149 (23.49%), Postives = 68/149 (45.64%), Query Frame = 1 Query: 1219 GYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 G + W+ID +++ + E + + S F+ G K C R++ + + G F L+ G +D ++ WP++ +V L+DQ + F T+ ++K+P S N G L T + +++D ++IK V+ Sbjct: 378 GTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQDRVHDIGD---TFRPDPTSSSFKRPTSNMNIASGCPLFISHTNLQTRAYVRDDTMFIKIAVDT 523
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO40665 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6K0]) HSP 1 Score: 62.3882 bits (150), Expect = 2.114e-10 Identity = 47/191 (24.61%), Postives = 96/191 (50.26%), Query Frame = 1 Query: 1099 KIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNE-AIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCA-----------GFCLIPGPYDNVIEWPYQMEVFISLIDQ-TNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLG-DKLIKFETFVHNTNLIKNDKIYI 1629 K+ ++ + H +++++ S I+I E+E K +G F W+I N+++++ + A K K+ S F++ G K+ +AE +L ++ G YD+V+ WP+Q V LIDQ + T + + + +C R ++ + +P K+ G G K + ET + + N ++++ ++I Sbjct: 190 KVKRIEMEKH-LQDSMASHLDMAHIRIRELEQRQEKICTNGKFLWKISNYTQLFQQSATKKEKEKLCSPPFYTGQYGYKL-----RAEAFLNGLGQGKGTHLSLYVVIMKGDYDSVLPWPFQQRVDFILIDQDDDFTSRQNKTWRLTCDRNSDYFGRPNKAKSLGFGCPKFVSQET-LKSRNFVRDNTVFI 373
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO41243 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z7]) HSP 1 Score: 60.8474 bits (146), Expect = 6.744e-10 Identity = 46/173 (26.59%), Postives = 78/173 (45.09%), Query Frame = 1 Query: 103 VIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKY-LNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSC--PLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNAD 612 V Y + +++E C +C L VP +CG RFC C+ + +S CP +P+DL +DV D + VKC C+++ EL +E H C+ +C P+ S R D+ ++HL+ + D+ + + D+ P L+ A ++N D Sbjct: 7 VPSGYDSEFVIAVAEEYTCRICHLPLRVPVQTKCGHRFCKECLDEASRRKSRAECPMDR-----EPLDLKKDVFLDKAAERTILSFLVKCPCKGCKWEAELRDLEAHARNCDYELVTCSNPMCSAQLPRMDV-----DEHLLVECDWRLIVCEYCGDESPYCLQK-AHARNCD 168
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91]) HSP 1 Score: 58.9214 bits (141), Expect = 3.550e-9 Identity = 38/143 (26.57%), Postives = 71/143 (49.65%), Query Frame = 1 Query: 1054 DEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRL------WKAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTN 1464 DE ++ +E+ E + K S D R + T K +++ EIE E +G F W++DNF + +I ++S F++ G KMCLR+ E++ ++ G +D ++EWP+ + +S++DQ++ Sbjct: 284 DEYRQFLAYLERKVEDV-KTSSD----RRIAELTHKLMRLETREIELEGRVC--NGTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHVSLFIHMMQGDWDGILEWPFIGRITLSILDQSD 419
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 78.5666 bits (192), Expect = 6.173e-15 Identity = 112/542 (20.66%), Postives = 217/542 (40.04%), Query Frame = 1 Query: 139 ISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQL-----KPIDL--DRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIE-DHISICNKSKNSCP-----LFSKGCDR-NDLLQDEMNQHL--------IKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQ-SE---KKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSI--MKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIK-----IMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 + D+ KC C +L P +CG RFC C + + P + C+ +P+ + + D+ ++ + +C++ C++ + E H C + C + K DR ND +E + KDI H ++ K P K+ + K + N +K+ A+S++A SE K + N + HE + ++ + + ++++ ++ S L Y+ ++ G + S D+ +++ ++ + +L E + ++ + L S Q +Q+K +E L KI +L + L T K+ Q+ + E+++ G F W+I +FS EA+ + S +F+S G KMCLRL+ +L F ++ YD +++WP+ +V + L+DQ N F T+ ++++P SE N G L + +++D I+IK +V+ Sbjct: 24 MEDKYKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSG----PKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIKAHDEICQK----FPLQCKDCGKKKIPREKFND-HAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNREVE------------------------RSSLTLEAFSHQHRLDQEK----IENLSNKIRQLERSL---------TVKDLQLSEAEQMVRELQY----CTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNREHIID---AFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVD 512
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 78.5666 bits (192), Expect = 6.350e-15 Identity = 112/542 (20.66%), Postives = 217/542 (40.04%), Query Frame = 1 Query: 139 ISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQL-----KPIDL--DRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIE-DHISICNKSKNSCP-----LFSKGCDR-NDLLQDEMNQHL--------IKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQ-SE---KKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSI--MKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIK-----IMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 + D+ KC C +L P +CG RFC C + + P + C+ +P+ + + D+ ++ + +C++ C++ + E H C + C + K DR ND +E + KDI H ++ K P K+ + K + N +K+ A+S++A SE K + N + HE + ++ + + ++++ ++ S L Y+ ++ G + S D+ +++ ++ + +L E + ++ + L S Q +Q+K +E L KI +L + L T K+ Q+ + E+++ G F W+I +FS EA+ + S +F+S G KMCLRL+ +L F ++ YD +++WP+ +V + L+DQ N F T+ ++++P SE N G L + +++D I+IK +V+ Sbjct: 31 MEDKYKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSG----PKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIKAHDEICQK----FPLQCKDCGKKKIPREKFND-HAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNREVE------------------------RSSLTLEAFSHQHRLDQEK----IENLSNKIRQLERSL---------TVKDLQLSEAEQMVRELQY----CTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNREHIID---AFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVD 519
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: unm_sa808 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101155367]) HSP 1 Score: 74.3294 bits (181), Expect = 1.586e-13 Identity = 59/232 (25.43%), Postives = 112/232 (48.28%), Query Frame = 1 Query: 982 DIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKL-QEKIDKLSQDLHEMRENV---DSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 ++++KSG+ +NV+ + + + + S KL Q+KI+ LS + ++ V D T E + ++ E+ + G F WRI +F+K +A+ + S +F++ G KMCLR++ +L F ++ G D +++WP+ +V + L+DQ+N F T+ ++++P SE N G L + I++D I+IK +V+ Sbjct: 369 ELEVKSGT-FENVVCVLNREVERFTTTMEASNRQHKLDQDKIEALSNKVRQLERTVGLKDLTVAEMEGRLREM----AATTFDGVFIWRISDFAKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGLSDALLKWPFNQKVTLMLLDQSNREHIID---AFRPDVTSSSFQRPVSEMNIASGCPLFCPLSKLDAKNSYIRDDTIFIKAIVD 592
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601]) HSP 1 Score: 70.0922 bits (170), Expect = 2.034e-12 Identity = 46/214 (21.50%), Postives = 103/214 (48.13%), Query Frame = 1 Query: 1045 QTYDEQQKLSGIVEKLQEKIDKLSQ------DLHEMRENVDSTKKEFQIKIMEIEFESGKSEK-SGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAG------FCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNN 1647 Q DE + L G ++ ++ ++ L Q + R + + E ++ M++ F+ ++ +G W+I ++ + +A+ + S F++ G KMC R++ + + G F ++ G YD ++ WP++ +V + L+DQ + + + K ++ ++++P +E N G L ++ + + IK+D I+IK V+ Sbjct: 233 QLRDEMESLRGTLDTVRTRLSALEQGGRASLETQLNRHDDMLSVHEIRLADMDLRFQVLETASYNGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPD--PSSSSFRRPVAEMNIASGCPLFVSQSVLESGTYIKDDTIFIKVTVDT 444 HSP 2 Score: 53.1434 bits (126), Expect = 5.490e-7 Identity = 38/139 (27.34%), Postives = 64/139 (46.04%), Query Frame = 1 Query: 115 YKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLD---RDVVSDHPMAVRLSQVKVKCIHD--NCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHL 516 ++ H ++ + C C+ +L P CG RFC+SCI L+ N CP ++P+ D RDV + +KV C + C+ L I DH+++C + CPL G + +++ E+ +HL Sbjct: 34 FRDHFVEAPEAKYCCEACRLVLCQPRQTECGHRFCYSCINDILSCPNPVCPA-----DMEPLFKDKIFRDVCCHR----EIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCPL---GKCKERMMRKEIPEHL 160
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626]) HSP 1 Score: 63.1586 bits (152), Expect = 4.993e-10 Identity = 49/208 (23.56%), Postives = 98/208 (47.12%), Query Frame = 1 Query: 1045 QTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEF-ESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLW------KAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLI-KFETFVHNTNLIKNDKIYIKCMVN 1644 + Y+ Q +L Q+KI+ LS + ++ V + ++ I ME + + + G F W+I +F+K +A+ + S +F++ G KMCLR++ +L F ++ G D +++WP+ +V + L+DQ N F ++ ++++P S+ N G L + I+++ I+IK +V+ Sbjct: 369 EAYNRQHRLD------QDKIEILSNKVRQLERTV--SLRDLSIVEMEGKMKDMSAATYDGIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIID---AFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDETIFIKAIVD 565
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000027283.1 (SMESG000027283.1) HSP 1 Score: 1141.72 bits (2952), Expect = 0.000e+0 Identity = 557/567 (98.24%), Postives = 560/567 (98.77%), Query Frame = 1 Query: 70 MPEDIFMDLWRVIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSE------KKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNNFKDIGMVRTLNTLEQPNKTIGSIRILDLYKNFSSS 1752 MPEDIFMDLWRVIQKYKYHLIDNISDEMKCGLCKY+LVVPCSIRCGCRFCHSC+TKYLNESNTYCPNKSK+CQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSE KKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFES KSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNNFKDIGMVRTLNTLEQPNKTIGSIRILDLYKNFSSS Sbjct: 1 MPEDIFMDLWRVIQKYKYHLIDNISDEMKCGLCKYMLVVPCSIRCGCRFCHSCLTKYLNESNTYCPNKSKYCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSENAAQSEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESVKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLRLWKAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNNFKDIGMVRTLNTLEQPNKTIGSIRILDLYKNFSSS 567
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000014706.1 (SMESG000014706.1) HSP 1 Score: 229.565 bits (584), Expect = 4.687e-68 Identity = 147/526 (27.95%), Postives = 284/526 (53.99%), Query Frame = 1 Query: 97 WRVIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESN-TYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQK----LSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLR-----LWKAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDK-LIKFETFVHNTNLIKNDKIYIKCMV 1641 W++I++ + LI+ +++++ C +CK I++ + CGCR+C CI ++LN ++ YCP +K+C + ID DRD+ D + +R+SQ+ VKC + CEF DELS +E+H+ C++ CP GC + ++ Q+E+N+HL+ D H KL+V+ +++ L+N + S ++N EN +S K+ ++ +H+ + I + E N++K++ +S+ + A + +K + +++ + + +EN+ + LKA +K+ + Q K + + + E D ++ +S VE+L+E ++ L ++ ++ ++ + K F+ ++ ++E E ++++ F W+I+NFSKV +A ++ N ++ SDSFF G +MCL L K+ ++ F ++ GPYDN++ WP Q++V + LIDQ + F S + + NE ++KP S N+G G IK + + L +N++++IKC+V Sbjct: 8 WKIIKENNFKLINPLNEDLTCLICKGIMINASNAPCGCRYCCQCIKQHLNGTDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLVVKCPMETCEFTDELSMMEEHLKDCDRKFVGCPYSEIGCCKPEVRQNEVNKHLLNDSFPHNKLLVEYVNN----LRNEIEELKTQMS--KTNTENFCLIENLGESRKRFI--YQQAVHKKE--------IDILAEENNAMKIQINSLNFKIGAFKQNEKQEQV----------QLKEEMSRLVEENKAIGIHINSLKAEIATLKKE--NKQEKLEKTLKGLEGKQEEIEGKVDFAERANKVISDKVEQLKETVNNLQGNIDSVKLDIFTEKLSFENRLSDLE-ERFDNQENKVFIWKIENFSKVIADAKQNRNKRIYSDSFFVFENGYQMCLYVCPIGLGKSSGFVGVYFNIMQGPYDNILAWPCQIDVTLELIDQDDGLAFKSSTKLYDFNSDNEVYEKPISGMNSGSGYPFFIKLDYLLKMNQLFRNNQLFIKCIV 504
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000021123.1 (SMESG000021123.1) HSP 1 Score: 224.172 bits (570), Expect = 3.800e-66 Identity = 158/531 (29.76%), Postives = 272/531 (51.22%), Query Frame = 1 Query: 97 WRVIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESN-TYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMN-----LRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVD---STKKEFQIKIMEIEFE-SGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLR-----LWKAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLG-DKLIKFETFVHNTNLIKNDKIYIKCMV 1641 W++I + + LI+ ++D++ C +CK I+V + CGCR+C CI KYLNE++ YCP SK+C + ID DRD+ D + +R+SQ+ VKC + C+F DELS +E H+ C++ CP GC + D+ +DE+N+HL + H KL+V +++ L+N ++ N+ S T + N ++ A+S KK EFQ++ K I ++ +E NS+K++ +S+ M+ L + DE ++L E + +L+ + + ES +N + ++ ++ L V L +ID L++D+ ++ ++VD ++K+ +++KI +I+ + S K F W++++F++V + + SD FF G KM L L K+ + F +I GPYD+++ WP Q++V LI+Q F S F + A++KP +EKN GLG IK + + LIKND+++IKC V Sbjct: 8 WKIISEKNFQLINPLNDDLICLICKGIMVNATNAPCGCRYCCLCIKKYLNETDDNYCPGLSKYCGINWIDFDRDICVDRSINIRISQLIVKCPMETCDFTDELSMMEKHLKDCDRKFIGCPYSEIGCCKPDIRKDEVNKHLFNESFPHNKLLVDYVNN----LRNEMEALNSKISAITTE--NICLAKTLAKSNKKF---------EFQQRTFKRE-IDKLTKENNSMKIQINSLNIKMTVLKQ---------------------------DEKQVLVQE-----------RLGLLEGRQEKTEESVGKLNEANTTINGTVDRLTNDMNSLKEDVGSLNNEIDDLTEDVSKLEDSVDEINTSKESYEMKIDKIQVQLDNLSNKE--FIWKLEDFTEVVENCKTKSTKMIISDFFFVSENGYKMGLYAYPKGLGKSAGFFGIYFNIIKGPYDDLLCWPCQIDVTFELINQETKCSFISKKKLFENNPDHTAYQKPTTEKNNGLGYPYFIKLDYLLKQNQLIKNDQLFIKCFV 482
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000049812.1 (SMESG000049812.1) HSP 1 Score: 223.016 bits (567), Expect = 8.862e-66 Identity = 146/541 (26.99%), Postives = 282/541 (52.13%), Query Frame = 1 Query: 82 IFMDLWRVIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESNTYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKN----TAQSKNADQSDNTAQSKNTAQSE---NAAQSEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQI-------KIMEIEFESGKSE--KSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCLR-LWKAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLGDKLIKFETFVHNTNLIKNDKIYIKCMVNNFK 1653 +F +LW+++++ ++ + I E+KC +CK +++ C+ CGCRFC CI +YL++++ +CP +++FCQ++ ++ R+V DHP+++R+S+V VKC NCE EL +E+H++ C+K SCP + GC N++ DEMN HL + H L++ +I++L + +++ + K + + KNTA+ E N + KK +LR+ + E ++N K ++++++++++S + + M + ++ N ++ + +E +LKNE++ + + QM++ +E+ N + ++ + +QQ D L Q+ + R + K FQ+ +I +I+ G KSG+F W ID SK + + ++ S F+S G KMCL + ++Y+ GF L+ +DN +EWP++ V I +ID N S S+K+S + W+KP S++N D + + + ++ KN+K+ +KC ++ F+ Sbjct: 1 MFTNLWKMMRENQFESDNEICSELKCRICKCLMIKACNAPCGCRFCSDCIEQYLSKNDKFCPGQARFCQVQKVNFTRNVSEDHPISLRISKVIVKCPRQNCETKTELIKMEEHMNNCDKRPISCPFNTFGCAINEVASDEMNAHLNESSYCHSNLLIAMINNLNSQMESMMNENMELKQRMRRMEAKERKNTAKIEDLNNVILAVKKNNQSLRDEMTELSKENRK------FKQQIDTIELQSADLQQKMGEMEAREQENAG--------------EIELLNEEMVVLKNEYRSMSS------------QMETNAEAINQIRMQIERIEINSQQQS------------DALKQNCEQQRLQAN---KNFQLEMEKCANEIRQIQSTFGYENFLKSGFFEWEIDKISK------QKRDNRIYSKPFYSGPFGYKMCLAVIIGGDDYIAVGFNLMRSDFDNNLEWPFKYSVAIDVIDSANGNIIDSRSVKYSDCPDDVGWRKPTSDRN----DPICIYYNSISIKSVAKNNKLLLKCKIDKFE 484
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Match: SMESG000014700.1 (SMESG000014700.1) HSP 1 Score: 218.779 bits (556), Expect = 2.231e-64 Identity = 149/526 (28.33%), Postives = 259/526 (49.24%), Query Frame = 1 Query: 85 FMDLWRVIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCHSCITKYLNESN-TYCPNKSKFCQLKPIDLDRDVVSDHPMAVRLSQVKVKCIHDNCEFDDELSAIEDHISICNKSKNSCPLFSKGCDRNDLLQDEMNQHLIKDIDFHIKLIVKIIDDLPATLKNTAQSKNADQSDNTAQSKNTAQSENAAQSEKKIFSNLREMLHEFQEKNDKSSVIQEIQRELNSLKVESHSIMKDMSALNEYKKLNETFGPSKSPAINDIRQRLKSVTDENEILKNEFQDLKALGVIIKESILDIQMKSGSESQNVMNLRTVSEQTYDEQQKLSGIVEKLQEKIDKLSQDLHEMRENVDSTKKEFQIKIMEIEFESGKSEKSGYFYWRIDNFSKVWNEAIKSNNGKVNSDSFFSQSKGCKMCL-----RLWKAEEYLCAGFCLIPGPYDNVIEWPYQMEVFISLIDQTNATEFASCSLKFSCYRTNEAWKKPKSEKNTGLG-DKLIKFETFVHNTNLIKNDKIYIKCMV 1641 F +W++I++ + LI+++ ++ C +CK I++ + CGCR+C CI ++LNE++ YCP +K+C + ID DRD+ D + +R+SQ+ VKC + CEF DELS +E+H+ C++ CP GC + ++ Q+E+N+HL+ D H KL+V+ +++L ++ + +++N ++ +++ DKS + E + LK E +++KD A+ DI+ + D N + QD + I + ++Q K S+N+ L+ +E K+S V L+E ID + D K F +++EI + F W+I+N SKV A +SNN K+ SD +F G +MCL L K + + F ++ GPYD+++ WP +++V LI+Q N + F S S K+ + +KKP +E+N G IK + + +I+ D+I+IKC V Sbjct: 4 FEIVWKIIKENNFKLINSLKKDLTCLICKGIMINASNAPCGCRYCCQCIKQHLNETDQNYCPGSNKYCGINLIDFDRDICIDRSINIRISQLTVKCPMETCEFTDELSMMEEHLKDCDRKFVGCPYSEIGCSKPEVRQNEVNEHLLNDSFLHNKLLVEYVNNLRNEIEELKTQMSLVKTENIC------------------------LIESLEKRGDKSGL------EQSKLKEELSALVKD-------------------NAVKDIQ-----IKDLNNKINTLIQDRRNDE--ISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESID-----------DFDMLKFAFAKRLIEITAQLN----VKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKSGVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIKCNV 458 The following BLAST results are available for this feature:
BLAST of TNF receptor associated factor-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor associated factor-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of TNF receptor associated factor-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of TNF receptor associated factor-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor associated factor-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor associated factor-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor associated factor-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor associated factor-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor associated factor-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor associated factor-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of TNF receptor associated factor-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor associated factor-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor associated factor-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor associated factor-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30033686 ID=SMED30033686|Name=TNF receptor associated factor-2|organism=Schmidtea mediterranea sexual|type=transcript|length=1768bpback to top protein sequence of SMED30033686-orf-1 >SMED30033686-orf-1 ID=SMED30033686-orf-1|Name=SMED30033686-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=562bp MPEDIFMDLWRVIQKYKYHLIDNISDEMKCGLCKYILVVPCSIRCGCRFCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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